LOCUS       DARYNN010000001        84004 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.001, whole genome shotgun sequence.
ACCESSION   DARYNN010000001 DARYNN010000000
VERSION     DARYNN010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 84004)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 84004)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..84004
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.001"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            <1..376
                     /locus_tag="TVB59_000001"
     CDS             <1..376
                     /locus_tag="TVB59_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="secretion protein"
                     /protein_id="HEL1008958.1"
                     /translation="QGGEKKDISYIEQEGDLSALFQSETDLSIKKKQQHRKETSQTTK
                     NHLFMTHIDSDNLVARYQPLLFNPEQRLAATDDQYGVLLAQKTIGITWQMLAILLVGA
                     VLTGYSLTRGRLSRQKHKRHHE"
     gene            692..933
                     /locus_tag="TVB59_000002"
                     /pseudo
     CDS             692..933
                     /locus_tag="TVB59_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678362.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type VII secretion protein"
     gene            936..2093
                     /gene="essB"
                     /locus_tag="TVB59_000003"
     CDS             936..2093
                     /gene="essB"
                     /locus_tag="TVB59_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VII secretion protein EssB"
                     /protein_id="HEL1008959.1"
                     /translation="MEKKMKTIIRELLVEDVKGDAEVAYTLLASEHSLFVPSKLEQAF
                     DKLILEASIDDMYDWSALEAMIVEEKLRHLLNLSELFDQLLDSKFTYSFTPDNLVFNR
                     NAEPQLIFRGIKDQVPPYQPLEREVFVNTLKCMTIALLDKKTSYDALMGGKLPFYKGN
                     LFCEAVAKAEALQELQELLATKYHEEQKDNKEHFSRVANKTISRLKLTTICSSVLALL
                     SLAGVLYFLLFAMPYQEMVASLRMAFINQDYSKVITTAKHTDSKALSQGDKYIVAYSV
                     IMTEPLTDKQKEELSKISNQSNEDYLRYWVLIGQARIDDAMDIASYLDDPQLLMYGLT
                     KKIDDVQRDPNLTAEARTEQLNSYKSKLDELKKAYLTPKEEKAAGSSSDKE"
     gene            2105..6481
                     /gene="essC"
                     /locus_tag="TVB59_000004"
     CDS             2105..6481
                     /gene="essC"
                     /locus_tag="TVB59_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VII secretion protein EssC"
                     /protein_id="HEL1008960.1"
                     /translation="MTYLIYDDNAYHLYSDTVYQLGPSSGSDIFLPLLEDITLSVEGS
                     GVVLLEESYSTGKHCVALSDEVTVTLLILEAVTKYLLPDSSLYISGETTAALQLLDYP
                     SELVLTLDSDSASCYSPVSYYLNGKWTKGKQPLKASDELVFSDGLVLSFQDQLLSIQS
                     LYAIQTALLPLTEAVAEDRASEFHRSPRIILREPEGKVTIASVPTDDEGKRQSLLKLI
                     ITPLAMIVFTGLSYVFFRGGGMLMMMMGMSVITIGSSIHSYFSDKKWHKEAQQQKIKD
                     YLAYLDTKYVELAGYREEQIEALLYHYPNMTTILEMAQKTDRRIYEKAPYHFDFLTYR
                     LGLGDTPASFHIDYSDSELTKHHEKAKQRVQELIAYYQVTAQVPIQNAIASPIGYIGA
                     RKVVIEQVQQLMMQIATFHSYHDVQFIPIFREEELPLWNWSRWLPHTKLKVLNSRGFV
                     YSQRTRDQLLTSLYQLIKERQLDSEQDKGTEKQYTPHYIVLITDMSLMLDHNIMEYIN
                     EDLSHLGIHYIFVEEVIESLPEHVKTVIDYRGDKHAQLILQEGLYLNKAFTPLQPLSM
                     KDKEVFARHMAGINHVETLRNAIPNSVTFLEMYGVNKVEELNLLKRWKENEAYQTMAV
                     PLGVRGRDDILYLNLHEKAHGPHGLIAGTTGSGKSELVQSYILSLAVNYHPYEVAFLL
                     IDYKGGGMANLFADLPHVVGTITNLDGNQANRALVSIKAELKKRQRIFLENDVNHIDQ
                     YTKLFKEGRVKEPLPHLLIISDEFAELKANQPEFMDELVSTARIGRSLGVKLILATQK
                     PSGVVNDQIWSNAKFKIALKVQDVADSREVIKTPDAAEITQVGRAYLQVGNNEIYELF
                     QSAWSGADYNPKGRHTIQHETTVYEITANGQYQAINKDLSGLDKKREAKSMPTELDAV
                     VAEAQQLFEDLHIPKVASPWLPPLSEKIYASDLQSTHFKDYWGQTQDLQPVLIGYQDI
                     PERQEQSPLYFHMEKAGHILLVSSPGFGKSTFLQGFALDVMRKQTPAQAHFYLYDFGT
                     SGLIALSDFPHVADYFTLDETDKIMKSLRYLSEEIKTRKHALSKAKATNLNQYNQLSK
                     DTFPALFVIIDGFDSVMDAPFVDAVYNVLNVIARDGASLGMYLVVTLSRLNTMRLQLQ
                     SNFKTKLSLFLFDNSDLSSVVGRSNIPLDDIKGRAIMKRDDIIQFQIALPYSSEYYTD
                     YMAEVKREVEAMRAVYQGALPAAIPMLPEKVTPDMIAAMSDSAQDFVIGLEREDVVPA
                     GFTFKKSILMASDSPAFVANYYKLLDFQLQRLADQYRTVILDPSQRIARQFFEDSQRF
                     STALDVGDTLRAIVEDFKKRLAAPGQDYQKWLVVIPDIAATALAAGISEEDFKQLVTE
                     GSQYGVTLIFVGAYQDLVNNTYDNFVKLANQLIEQVFLGMRISDQSHTRYAYISNEPS
                     LRPTQGYILYPEGYDFIQLLEI"
     gene            6494..6823
                     /locus_tag="TVB59_000005"
     CDS             6494..6823
                     /locus_tag="TVB59_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
                     /protein_id="HEL1008961.1"
                     /translation="MSTVTMLPLGSIVILKGNTKKMMIIARVIAAPIKGEVYRFDYGA
                     CLYPEGMMGDSLIYFNHDDIFKIIQEGYADDDNALMLETIAQALATTDIPKGDVSALN
                     DRKTVED"
     gene            6827..7261
                     /locus_tag="TVB59_000006"
     CDS             6827..7261
                     /locus_tag="TVB59_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5082 family protein"
                     /protein_id="HEL1008962.1"
                     /translation="MGQVDYNHINQLQRQVDQHRASLSTATAEIASIDEKLERLRCAK
                     ASVGAIQGDVHQIKVSVMAKRDQPDWKGERKDRLMSSWEEFSHDYRHFQLELDAYYDA
                     ICDTITRLENQKYEQQGLIGWCQSMINSLGNEIEKLFHIREG"
     gene            7263..7547
                     /locus_tag="TVB59_000007"
     CDS             7263..7547
                     /locus_tag="TVB59_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04197 family type VII secretion effector"
                     /protein_id="HEL1008963.1"
                     /translation="MFGVIQLSEVVFGAHVLSLTAAKASLSDVKASFPSHQSSSKVLD
                     LYQSEFEALSQLVAAYARLLEKDIALIAEAGQELALTDKQLGQAIGFRLQ"
     gene            complement(7618..8920)
                     /locus_tag="TVB59_000008"
                     /pseudo
     CDS             complement(7618..8920)
                     /locus_tag="TVB59_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400088.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            9301..10011
                     /gene="ccdA2"
                     /locus_tag="TVB59_000009"
     CDS             9301..10011
                     /gene="ccdA2"
                     /locus_tag="TVB59_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEL1008964.1"
                     /translation="MELTMLLMVSVFIAGLLSFFSPCIFPVLPVYLGILLDSDDSRSI
                     TIFGKKLYWYGIVKTLAFISGLSTIFIILGYGAGLLGNILYAAWFRYLLGAFVILLGI
                     HQMEIVTIKKLQFQKSVAFQNKKDRNAVLNAFLLGITFSFGWTPCVGPVLSSVLALAA
                     SGGSGAWQGGFLMIIYTLGLGLPFLLLSFASGIVLKHFNKLKPHIPLLKKLGGLLIVI
                     MGLLLMTGNLNSLSGLFE"
     gene            10025..10675
                     /locus_tag="TVB59_000010"
     CDS             10025..10675
                     /locus_tag="TVB59_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002933805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HEL1008965.1"
                     /translation="MKKTTFLTTGLACLALLTACSAKDKMAMNDSKKDHMTRTDDKSK
                     MKKDQKDKMSDKKDMMSDDKHMSDADKASKNDGQMAPDFELKSIDGKTYRLSDFKGKK
                     VYLKFWASWCSICLSTLGDTQSLATMKDKDFEVLTIVSPGHQGEKSEADFKKWFEGTD
                     FKDLPVLLDPDGKLLEAYGVRSYPTEIFVGSDGVLAKKHIGYAKKSEIEKTLKEIK"
     gene            10693..11805
                     /gene="msrB"
                     /locus_tag="TVB59_000011"
     CDS             10693..11805
                     /gene="msrB"
                     /locus_tag="TVB59_000011"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEL1008966.1"
                     /translation="MEHKWKLLLLVFGALVFLGGVLMVFQRGYATSYHNNQVKLPAKG
                     TSQLKKTANAKLPEKKKEIYLAGGCFWGVEEYFSNVDGVLDAVSGYANGRGDTTSYQL
                     LHQTGHAETVQVVYDANRISLKELLLHYFRIIDPTSLNKQGNDRGSQYRTGIYYTDPS
                     DLTTIDMVFQEKASDYKKKIVVEKAPLKSFTKAEEYHQDYLKKNPNGYCHINVNEASY
                     PVIDKTKYPKPSKEEIKKKLSKDEYRVTQNNETEKAFSNRYWDSFEAGIYVDVVTGEP
                     LFSSKDKFESGCGWPSFSRPISPDVLRYKTDKSFNMNRTEVRSRSGNSHLGHVFTDGP
                     KDQGGLRYCINSLSIRFIPKAEMEAKGYGYLLTAVD"
     gene            12073..12813
                     /locus_tag="TVB59_000012"
     CDS             12073..12813
                     /locus_tag="TVB59_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEL1008967.1"
                     /translation="MYSLLIVEDEYLVRQGIRSLVDFDQFAIDRIAEAENGQVAWELF
                     QENPYDIVLTDINMPKLNGIQLAELIKARAPKTHLVFLTGYDDFNYALSALKLGADDY
                     LLKPFSKSDVEEMLKKLKQKLEKLKKTEALQKLVDKPQQEGSEIKLAIQERLADSSLT
                     LKSLSSQLGFSPNYLSVLIKKDLGLPFQDYLIQERLKKAKLLLLTTDLKVYEIAEQVG
                     FEDINYFSQRFKQLVGMTPRQYKKGEGQ"
     gene            12810..14528
                     /locus_tag="TVB59_000013"
     CDS             12810..14528
                     /locus_tag="TVB59_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL1008968.1"
                     /translation="MKRYPLLVQLVSYFFLIVISLITILGVIYYQTSSHNIRQLIERE
                     TRQSIRQSSQFIDAYIKPLKETTSALASHAEIQSFAKAANSSHQEQVLALMTTVLSTN
                     SDLRSAVLVTKDGRMVTTNPKLIMTTSHDMMAEPWYKSAIDRKAMPVLTPARQLSSHS
                     KKDWVVSVTQEVVDETGNNLGVLRLDIGYNTIKSSLDQLQLGRRGFAFIVNDKHEFVY
                     HPKNTVYSSEREMAAMKPYLAVADGYTKPKDYFVYQRVIPDSQWTLIGVASLDQLYHV
                     QRQIFWSFLGTGLLATVICGLGTVFVLRSWIGPIRRLQALILAIQKGNRQLRAEEIGS
                     PELADLARQFNAMLDQIDSLMISVADKEKAIGQYRLQALASQINPHFLYNTLDTIIWM
                     AEFNDSQRVVDVTKSLAKYFRLALNQGNELISLADELDHARQYLFIQKQRYGDKLHYE
                     IKGLEKYQDFMIPKLILQPLVENAIYHGIKEVDRPGMIRVTVLEADRHVILSVWDNGK
                     GISLADDSSQALLECGGVGLKNVDQRLKLQYGHLYRMAITSEQAVFTEIKLYLPKPLD
                     GLNELP"
     gene            14567..15655
                     /locus_tag="TVB59_000014"
     CDS             14567..15655
                     /locus_tag="TVB59_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEL1008969.1"
                     /translation="MSLESDYFKRKSPVFEALIPYGFTQEGDTYCYQESFMEGDFKAL
                     ITIKSSGQLSARVIDTDLGEDYLPLRNDRQQGVYVGQVRQAYLELLGRLSAACFRSTP
                     FQTRQANQVATSISQQWNDPLDYPFEKFPNIATYRVSGKWYAMVLPLLADKLGQVPKV
                     LQGQMVEVLTVRIAPNQLTHLLQQRGVYPAYHMSKKTWISLLLDGTLADDQLWELVTK
                     SRQLANPNGLANPDGPDYWVIPANLSYYDIDAEFAANPDILWTQKASIKAGDYVFIYI
                     TAPTRSIRYACQVLRSDIPNQGYRKNAKIKTLMSLRLLHCYEDGLISLDLMKQYGVNA
                     VRGPRRLSPQLVAFLKEKEYFKDVKQKE"
     gene            15670..16374
                     /locus_tag="TVB59_000015"
     CDS             15670..16374
                     /locus_tag="TVB59_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B3/4 domain-containing protein"
                     /protein_id="HEL1008970.1"
                     /translation="MTQFIADQSFWELFPDAKLGVLLLRNYDNQEDSPQEVKQLLADS
                     HDIAKQYLTEESFSDNEIIQVYRQAYQRFKTKKGARSSIEALLKRVANGQVLSSINPL
                     VDIYNTASLRFGLPVGAEDSDCFVGDLRLTLTEGGDEFYLIGDSKNSPTLPNELCYKD
                     DAGAVCRCLNWRDGERTMITDRTKNAFLVIEALDSKTQARLQDALKFIEDKAKCYLKA
                     ETALYTLDQASPSITF"
     gene            16634..17122
                     /locus_tag="TVB59_000016"
     CDS             16634..17122
                     /locus_tag="TVB59_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003032586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HEL1008971.1"
                     /translation="MELFDKVDDTLKALAIDYQLVEHEPALTTEQADQFIEGIEGVRT
                     KTMFLTTRKKNHFYLIIMDDTKRLDMNRFKELVGEKQIKMASAECLLAKMQLPPGVVS
                     PFGLLNNEDKDIQVYVDKAIAHEARMSFHPNTNDKTIFIQTDDLFKFLAAIGYAVNIV
                     DL"
     gene            complement(17632..18105)
                     /locus_tag="TVB59_000017"
     CDS             complement(17632..18105)
                     /locus_tag="TVB59_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEL1008972.1"
                     /translation="MNKKETRHQLIRSLISETTIHTQQELQERLRKNGISITQATLSR
                     DMKELNLVKVTTGNDTHYEALAISQTRWEHRLRFYMEDALVMLRVVQHQIILKTLPGL
                     AQSFGSILDAMQISEIVATICGDDTCLIICEDNEQAKACFEILSHYTPPFFFSNK"
     gene            18246..18926
                     /locus_tag="TVB59_000018"
     CDS             18246..18926
                     /locus_tag="TVB59_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEL1008973.1"
                     /translation="MIRREDYQYLRKLDDFCHFSIEQFDKIVGQMEFRQAKKDHMLFF
                     EGDKRDRLFLVTSGYFKIEQSDRTGTFTYTDFIRHGTIFPYGGLFTDDYYHFSVVAMT
                     DVTYFYFPTDLFEDYSLHNQQQMKHLYSKMSSLLELHELKVRNLITSSASSRVIQSLA
                     ILLVEMGKDSDTLPFQLTTTDIAQMSGTTRETVSHVFRDLKKEGLIAVKGKYLTYLDK
                     NYFLQYTT"
     gene            19195..20430
                     /gene="arcA"
                     /locus_tag="TVB59_000019"
     CDS             19195..20430
                     /gene="arcA"
                     /locus_tag="TVB59_000019"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEL1008974.1"
                     /translation="MTAQTPIHVYSEIGKLKKVLLHRPGKEIENLMPDYLERLLFDDI
                     PFLEDAQKEHDAFAQALRDEGVEVLYLETLAAESLVTPEIREAFIDEYLSEANIRGRA
                     TKKAIRELLMSIEDNQELIEKTMAGVQKSELPEIPAAEKGLTDLVESSYPFAIDPMPN
                     LYFTRDPFATIGTGVSLNHMFSETRNRETIYGKYIFTHHPIYGGGKVPMVYDRNETTR
                     IEGGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKQNLGFKKVLAFEFANNRKFMHL
                     DTVFTMVDYDKFTIHPEIEGDLRVYSVTYENEELRIVEETGDLAELLAANLGVERVEL
                     IRCGGDNLVAAGREQWNDGSNTLTIAPGVVVVYNRNTITNAILESKGLKLIKIHGSEL
                     VRGRGGPRCMSMPFEREDI"
     gene            20440..20871
                     /locus_tag="TVB59_000020"
     CDS             20440..20871
                     /locus_tag="TVB59_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1008975.1"
                     /translation="MTRVIVGNQPFQRAASLYIRYQVFVLERQIDRQDEFDCFDDNDR
                     VYAVLYDGDQPVSTARFLPTAKDQARLTRVATLRQYRGRGYGAQVIEALEQYAREQAY
                     ERLVIHSEISAQSFYEGLGYQAFGEPYDEDGEPCQSVEKYL"
     gene            20886..21899
                     /gene="argF"
                     /locus_tag="TVB59_000021"
     CDS             20886..21899
                     /gene="argF"
                     /locus_tag="TVB59_000021"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000195397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEL1008976.1"
                     /translation="MTQVFQGRSFLAEKDFTREEFEYLIDFAAHLKDLKKRGIPHHYL
                     EGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRMF
                     DGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVKENFGKLEGLTLVY
                     CGDGRNNVANSLLVAGTLLGVNVHIFSPKELFPAEDIVKLAEGYAKASGAHVLVTDNA
                     DEAVKGADVLYTDVWVSMGEEDKFEERVKLLKPYQVNMELVKKAANDNLIFLHCLPAF
                     HDTNTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLFI
                     PKV"
     gene            22061..23554
                     /locus_tag="TVB59_000022"
     CDS             22061..23554
                     /locus_tag="TVB59_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEL1008977.1"
                     /translation="MTEEKKRGFKIPSSYTVLFIIIAIMAVLTWFIPAGAYETAKDGG
                     VISGTYQTVKSNPQGFFDILMAPVRGMLGVKGTEGAIQVSFFILMVGGFLRVVNKTGA
                     LDTGIASVVRKNKGREKLLIAILIPLFALGGTTYGMGEETMAFYPLLIPVMIAVGFDS
                     IVAVAIILIGSQIGCLASTINPFATGVAADAAGVSIADGMIWRIIQWVVLVGMSIWFV
                     YSYASKIEKDPSKSLVADKAEEHKEFFQLQNSGEDLTSRQRKVLAIFTLTFVIMILSL
                     IPWEDFDIQLFTNINTWLTTTPVLGGIIGKTMGAFGTWYFPEITMLFIMMGVLVAVVY
                     RMSEDDFFSAFLSGAGEFLGVAIICAVARGIQVIMNGGMITATILHWGETGLAGLSSQ
                     VFVVLAYIFYLPMSFLIPSTSGLAGATMGIMAPLGQFSNVPAHLVITAFQSASGILNM
                     ISPTSAIVMGALALGRIDLGTWWKFIGKFIVMVMLVSVLLLVVATFF"
     gene            23571..24902
                     /locus_tag="TVB59_000023"
     CDS             23571..24902
                     /locus_tag="TVB59_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEL1008978.1"
                     /translation="METYIQPRHQEACVAAIKKIVSYPSVLNEGENDTPFGQAIQDVL
                     EATLALCQDLGFNTYIDPKGYYGYAELGDQTEVLAILCHLDVVPAGDLKLWHKDPFTC
                     IEKDGCLYGRGTQDDKGPSMMALFATKALMDAGVVFNKRIRFIFGTDEETLWRCMNRY
                     NEVEEEATFGFAPDSSFPLTYAEKGLLQAKLVGKGSPKLNLEVGQAYNVVPARASYQG
                     DKLEALKEELDRLGFEYVVKDDELTVYGLAQHAKDAPDGINALIRLAKALVVLEPEPV
                     LDFLAHVVDEDGRAVNIFGPVQDEPSGGLSFNVAGLTLTKEMTEIRLDIRIPVLADKD
                     TLVDQLSQKAQDYGLAYEEFDYLAPLYVPLDSELVTTLLEVYRKKTGDQSPAQSSGGA
                     TFARTMANCVAFGALFPDAVQTEHQENEHIVLADAYRAMDIYAEAIYRLTR"
     gene            24920..25870
                     /gene="arcC"
                     /locus_tag="TVB59_000024"
     CDS             24920..25870
                     /gene="arcC"
                     /locus_tag="TVB59_000024"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEL1008979.1"
                     /translation="MTKQKIVVALGGNAILSTDASAKAQQEALVSTSKSLVKLIKEGH
                     EVIITHGNGPQVGNLLLQQAAADSEKNPAMPLDTCVAMTEGSIGFWLVNALDNELQAQ
                     GITKEVAAVVTQVIVDENDPAFKNPTKPIGPFLTEEDAKKQMAESGASFKEDAGRGWR
                     KVVPSPKPIGIKEANVIRSLVDSGVVVVSAGGGGVPVVKDPASKTLTGVEAVIDKDFA
                     SQTLSELVDADLFIVLTGVDNVYVNFNKPDQRKLEEVTVSQMKEYIAQDQFAPGSMLP
                     KVEAAIAFVENKSNAKAIITSLENIDNVLSANAGTQIIAG"
     gene            26090..27082
                     /locus_tag="TVB59_000025"
     CDS             26090..27082
                     /locus_tag="TVB59_000025"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEL1008980.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLIAKLDVVEVQGPILSRVGDGM
                     QDNLSGVENPVSVHVLNIPNATFEVVHSLAKWKRHTLARFGFNEGEGLVVNMKALRPD
                     EDSLDQTHSVYVDQWDWEKVIPDGQRNLAYLKETVETIYKVIRLTELAVEARYDIEAV
                     LPKKITFIHTEELVARYPDLTPKERENAITKEFDAVFLIGIGGVLPDGKPHDGRAPDY
                     DDWTSESENGYHGLNGDILVWNEQLGTAFELFSMGIRVDEEALKRQVDITGDQERLQF
                     DWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKKHIGEVQTSVWPQEVRDTYDNIL"
     gene            27254..27793
                     /gene="rsmD"
                     /locus_tag="TVB59_000026"
     CDS             27254..27793
                     /gene="rsmD"
                     /locus_tag="TVB59_000026"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEL1008981.1"
                     /translation="MRIVSGEFGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFKGGR
                     VLDLFAGSGGLSIEAISRGMSEAVLVERDRKAQAIIQANIKMTKASQQFTLLKMNAER
                     ALDHLSGQFDVVFLDPPYAKETIVANIEALVEKNLLSDDVMIVCETDRSVALPEAIAW
                     LGIWKEKQYGISKVTVYVR"
     gene            27783..28283
                     /gene="coaD"
                     /locus_tag="TVB59_000027"
     CDS             27783..28283
                     /gene="coaD"
                     /locus_tag="TVB59_000027"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEL1008982.1"
                     /translation="MSGKIGLYTGSFDPVTNGHMDMIKRASHLFEHVYVGIFNNPNKQ
                     SFFTFELRAQMLSEAVCALPNVTVVSAEHGLAVDLARELSVTHLIRGLRNTADFDYEI
                     GLEYFNHRLAPDIETIYLMATHDLQPVSSSRIRELIAFRAPITGLVPQAVINQVEKMN
                     ENNKKN"
     gene            28261..29298
                     /locus_tag="TVB59_000028"
     CDS             28261..29298
                     /locus_tag="TVB59_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEL1008983.1"
                     /translation="MKTIKKIKWWLIGFVALLFLLLTLFFPLPYYIEMPGGAYDIRSV
                     LTVNGKEDKEKGAYQFVVVSLSRATLAKLLYAWLTPFTEISTMEDTTGGYSDADYLRI
                     NRFYMETSQNSAVYQALTLAGKEVSFDYKGVYVLDVSKDSSFKGVLHLADTVTGVNGK
                     TFTTSADLIDYVSHLTLGDEVQVQFTTAGESKTEKGKIIKLKNGKNGIGITLTDHTQV
                     ISGDEVDFSTGGVGGPSAGLMFTLDIYDQINHEDLRKGRVIAGTGTIGKDGKVGDIGG
                     AGLKVAAAAAAGADIFFVPNNPVHKDVKKANPKAISNYEEAKKAAKRLKTAMKIIPVK
                     TVQDAISYLKK"
     gene            29860..30474
                     /locus_tag="TVB59_000029"
     CDS             29860..30474
                     /locus_tag="TVB59_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEL1008984.1"
                     /translation="MKRDILPEMYNYNKFPGPEFIHFDHYVKAEGIELLLLKNEKNAF
                     NTTSFGQRFTEILLKYDYIVGDWGNEQLRLKGFYKDHHDVKKASRISRLEDYIKEFCN
                     FGCAYFVLENPNPKDMPKEEERPSRRRKSSKANRRRNQPQHSQQAPAKDNFKKLTKDR
                     SADKPSFTSKKRPAPNKTKGNQRRSRTSQLNHKTDHFIIRKKDN"
     gene            30478..31560
                     /gene="rlmN"
                     /locus_tag="TVB59_000030"
     CDS             30478..31560
                     /gene="rlmN"
                     /locus_tag="TVB59_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEL1008985.1"
                     /translation="MKPSIYGLTRDELIAWAIDNGQKAFRATQIWDWLYRKRVQSFDE
                     MTNISKEFVAILKDSFCINPLKQRVAQESADGTVKYLFELPDGMLIETVLMRQHYGQS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNSGEITAQIMMVQNYFDKRAQDERVSHVVVM
                     GIGEPFDNYQNVMTFLRTINDDHGLAIGARHITVSTSGLAHKIREFANEGVQVNLAVS
                     LHAPNNELRSSIMRINRSFPLDKLFSAIEYYIETTNRRVTFEYIMLNKVNDGVEQAQE
                     LADLTKRIRKLSYVNLIPYNPVSEHDQYSRSPKERVAAFYDILKKNGVNCVVRQEHGT
                     DIDAACGQLRSNTMKKDRQKAAAART"
     gene            32842..33372
                     /locus_tag="TVB59_000031"
     CDS             32842..33372
                     /locus_tag="TVB59_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEL1008986.1"
                     /translation="MTNTLVENIYASVTHNISKKEASKNEKTKAVLNQAVADLSVAAS
                     IVHQVHWYMRGPGFLYLHPKMDELLDRLNANLDEMSERLITIGGAPYSTLEEFSQHSK
                     LDETKGSYDKSVAQHLARLVEVYLYLTSLYQVGLDITDEEGDAASNDLFTAAKADAEK
                     TIWMLQAERGQGPAIF"
     gene            33745..33978
                     /locus_tag="TVB59_000032"
     CDS             33745..33978
                     /locus_tag="TVB59_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEL1008987.1"
                     /translation="MKTLYDVQQLLKGFGIVIYMGKRLYDIEMMKIELQRLYDGGLLD
                     KQAYLTAELILRREHRLELKREGQENESKIDRD"
     gene            33953..34924
                     /locus_tag="TVB59_000033"
     CDS             33953..34924
                     /locus_tag="TVB59_000033"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEL1008988.1"
                     /translation="MSQKLIGIDLGGTTIKFGILTSEGDVQEKWAIETNVLEDGKHIV
                     PDIVASLKHRLDLYGLTKDDFIGIGMGSPGAVNRTDHTVTGAFNLNWRGTQEVGSVIE
                     RELGIPFAIDNDANVAALGERWVGAGDNNPDVVFMTLGTGVGGGIIADGNLIHGVAGA
                     GGEIGHMIVEPLKGFACTCGSQGCLETVASATGVVKVARLLAEAYEGDSSIKAAIDNG
                     EAVSSKDIFVAAEAGDAFANSVVEKVSYYLGLAAANISNILNPDSVVIGGGVSAAGEF
                     LRSRVEKYFMTFTFPQVRQSTKIKIAELGNDAGIIGAASLARQFITE"
     gene            34934..35314
                     /locus_tag="TVB59_000034"
     CDS             34934..35314
                     /locus_tag="TVB59_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEL1008989.1"
                     /translation="MSPLTMIGWVLLAGVIAYYLWNYVSYRRMAKQVDNDTFKELMRQ
                     GQVIDLRDPASFRARHILGARNFPAQQFTTSIKALRKDKPILLYENVRPQYRVKAVKT
                     LRKAGYTDLYVLKAGLDYWNGKVK"
     gene            35710..37551
                     /gene="typA"
                     /locus_tag="TVB59_000035"
     CDS             35710..37551
                     /gene="typA"
                     /locus_tag="TVB59_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEL1008990.1"
                     /translation="MTKFREDIRNVAIIAHVDHGKTTLVDELLKQSHTLDERKELQER
                     AMDSNDLEKERGITILAKNTAVAYNDVRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQNLTPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LEFPVVYASAINGTSSLSDDPADQEKTMAPIFDTIIDHIPAPVDNSAEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERKEIQEAKAG
                     DLIAVSGMEDIFVGETITPTDCVEALPVLRIDEPTLQMTFLVNNSPFAGREGKWVTSR
                     KVEERLLVELQTDVSLRVEPTESPDKWIVSGRGELHLSILIETMRREGYELQVSRPEV
                     IIKEIDGVKCEPFERVQIDTPEEYQGAIIQSLSERKGDMLDMQMVGNGQTRLIFLIPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPVVAGEIGGRHRGALVSIENGKATTYSIMR
                     IEERGTIFVNPGTEVYEGMIVGENSRDNDLGVNITTAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAARDKANKKKKSAE"
     gene            37633..37887
                     /locus_tag="TVB59_000036"
     CDS             37633..37887
                     /locus_tag="TVB59_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEL1008991.1"
                     /translation="MFYLIIAALITSYYLFMAPKSVRNTLGMIGLVGLVALLIVLAGL
                     SFIKIMQTPKEIFVGLAMIVLGYYALRDIQKIPKKPKSKH"
     gene            38033..39394
                     /locus_tag="TVB59_000037"
     CDS             38033..39394
                     /locus_tag="TVB59_000037"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEL1008992.1"
                     /translation="MKTITEFQNKKVLILGLAKSGEAAARLLARLGAIVTVNDSKPFE
                     ENPAAQALLEEGIRVICGSHPLELLDEDFYCMVKNPGIRYDNPMVVRALDKAISILTE
                     VELAYLVSEAPIIGITGSNGKTTTTTMIADVLNAGNHSALLAGNIGFPASEVAQAATA
                     KDILVMELSSFQLLGTEQFQPHIAVITNLVPTHLDYHGSFEDYIAAKWRIQHRMTDKD
                     YLVLNADQELVKSLAQKTKASPVFFSTKEKVDGAYLADGYLYFKEERLMSAAELGVPG
                     RHNIENALATIAVAKLRGISNQVISRTLSHFRGVKHRLQLVGTLNQVTFYNDSKSTNI
                     LACQKALSGFDNSKVILIAGGLDRGNEFDELVPDLVGLKKMILLGESAERMKRAADKA
                     GVSYLDAKDVAAATKIAFEQAKAGDIILLSPANASWDMYPSFESRGDEFLAAYDALKG
                     EAQ"
     gene            39391..40473
                     /locus_tag="TVB59_000038"
     CDS             39391..40473
                     /locus_tag="TVB59_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEL1008993.1"
                     /translation="MTKKIIFTGGGTAGHVTLNLILIPKFIKDGWEVHYIGDDKGIEH
                     QEIKKSGLDVTFHAIATGKLRRYFSWQNLLDIFKVGFGVMQSLFIIARLRPKALFSKG
                     GFVSVPPVIAARLLGVPAFIHESDLSMGLANRIAYRFATTMYTTFEQEQTLAKLKHVG
                     AVTKVTGPGSRSVTSKQLEAVLEYFDPNLKTLLFIGGSAGARVFNRFITDHPELKEDF
                     NIINISGDPSLNELSWHLYRVDYVTDLYQPLMEMADLVVTRGGSNTLFELLAMRKLQL
                     IIPLGKEASRGDQLENAHYFTTRGYAEQLLEQELTLPHFQEKVREVFAKQSDYLSAMK
                     SSSELQSPESFYQLLSADISSATKEN"
     gene            40474..41664
                     /locus_tag="TVB59_000039"
     CDS             40474..41664
                     /locus_tag="TVB59_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="HEL1008994.1"
                     /translation="MADKTKHSEEKAALTEWQKRNIEFLNKKQQQAEKDKKLKEKLLN
                     EKIAQAQGEAASKADQEDTDEAEEKTEVSQAGTDEGEPLPEASEQEVPSPKDKPLKVP
                     KEKSPKQQALQKGWPVLLVSFVVLCLSIFMITPYSKVKDFSVKGNKKTSVEDLVRDSG
                     IKSSDYWITLLASPGSYENAVLKANPWVKKVALRYGFPNHFRFDVTEFDIIAYAQVAE
                     GFQLILENGKRVAAVKQAALPKSFLILNLEHEKEIQDVINRLTKIPSDLVKAIKSVSS
                     ANSQTTKDLLLLEMHDGNLIRVPRSQLELKLPYYQKIKKNLDTASIVDMEVGIYTTTA
                     EIENMPEVPASAQASQADKPAEASPEQGEEQATQEQPSPETPANPEATNPSVAQPTEQ
                     ANQQ"
     gene            41876..43240
                     /gene="ftsA"
                     /locus_tag="TVB59_000040"
     CDS             41876..43240
                     /gene="ftsA"
                     /locus_tag="TVB59_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEL1008995.1"
                     /translation="MARNGFFTGLDIGTSSIKVLVAEFISGEMNVIGVSNVPSTGVKD
                     GIIIDIEAAAAAIKTAVEQAEEKAGMTIERVNVGLPANLLQIEPTQGMIPVPSESKEI
                     KDEDVDSVVKSALTKSITPEREVISLVPEEFIVDGFQGIRDPRGMMGIRLEMRGLIYT
                     GPSTILHNLRKTVERAGIKVENIIISPLAMAKAVLNEGEREFGATVIDMGGGQTTVAS
                     MRAQELQYTNIYAEGGEYITKDISKVLKTSMSIAEALKYNFGQADMAEASLTDTVKVD
                     VVGSDEPVEVTERYLSEIISARVRHILDRVKQDLERGRLLDLPGGIVLIGGGAIMPGV
                     VEVAQEIFGTNVKLHIPNQVGIRNPMFANVISLVEYVGMMSEVDVLAQNAVSGEELLR
                     RKPIDFTGQEAYLPDYNETRGFEPAPNYEQQVPQADYEPQEPAEPKQKISERVRGIFG
                     SMFD"
     gene            43264..44592
                     /gene="ftsZ"
                     /locus_tag="TVB59_000041"
     CDS             43264..44592
                     /gene="ftsZ"
                     /locus_tag="TVB59_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEL1008996.1"
                     /translation="MAFSFDTASIQGAIIKVIGVGGGGGNAINRMIDEGVAGVEFIAA
                     NTDIQALSSSKAETVVQLGPKLTRGLGAGGQPEVGRKAAEESEEVLTEALTGADMVFI
                     TAGMGGGSGTGAAPVIARIAKSLGALTVAVVTRPFGFEGNKRSNFAIEGIQELREQVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITSPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERIVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDMTLTEA
                     EEASEIVGQAAGQGVNIWLGTSIDDSMRDEIRVTVVATGVRQDKAEQASGFRQPRTYT
                     QSNAQQAAGAQYASEQVRQTAQPSFDRRSSSFDFDMGETREMPKSQQAMPAHGHNHNQ
                     GSAFGNWDLRRDNIARPAEGELDNQLNMSTFSSNDDIDDELETPPFFKNR"
     gene            44595..45266
                     /locus_tag="TVB59_000042"
     CDS             44595..45266
                     /locus_tag="TVB59_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEL1008997.1"
                     /translation="MDLQKNKDIVFENIRLATQAANRPENSVSVIAVTKYVDKAVAGQ
                     LIDMGIEHIAENRIDKFLDKYEALKDRQVTWHFIGTLQRRKVKEVINKVDYFHALDSV
                     KLALEIEKRADHPVKCFLQVNISEEESKHGFKIAELDAAIEEISKMEKLHLVGIMTMA
                     PIDASQQELRSIFQKANQLRKNLQSKKRKNMPFTELSMGMSNDYPIAIQEGSTFVRIG
                     TSFFH"
     gene            45279..45941
                     /locus_tag="TVB59_000043"
     CDS             45279..45941
                     /locus_tag="TVB59_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEL1008998.1"
                     /translation="MAIKDAFNKMISYFDTDGVSEVEEELSSKKQEEPVTKSQQTSRP
                     NQQQQAARASQPQQPKQARPQMQAQQRPQSQSRAAYAERPYQGQSQARVSHDYNDRRA
                     TSAPSASSRREQYQHAAHQEQTTIALKYPRKYEDAQEIVDLLIVNECVLIDFQYMLDA
                     QARRCLDFIDGASKVLYGTLQRVGSSMYLLTPSNVSVNIEEMNIPNNGQDIGFDFDMK
                     RR"
     gene            45946..46203
                     /locus_tag="TVB59_000044"
     CDS             45946..46203
                     /locus_tag="TVB59_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEL1008999.1"
                     /translation="MIFILLILLKLIKVYSYLLLVYALLSWFPGAYDSWLGRLVSDIV
                     EPILKPFRSLNLQFAGLDFTIYLVMIGLNVLSEILIRVLIS"
     gene            46200..46994
                     /locus_tag="TVB59_000045"
     CDS             46200..46994
                     /locus_tag="TVB59_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEL1009000.1"
                     /translation="MTVQTMLYQHFQPDEHPFIERMLDLIARVEANYLLEVTDFLNPR
                     EVTILKGLVAATNLQCFSSTDYYPSEYGRVIVAPDYYCLDKADFDLALIEVTYNAKFN
                     QLTHAQILGTLINELGIKRALLGDIFVEIGHAQVMINRQLLSYCLGTIAKIAKARVKL
                     KEIDLDQLLNLTANQQVLTDIMVSSLRVDRLIATVLKQSRNQAIRLVEAGKVKVNYQL
                     VTKASQPVAVGDLISIRGYGRFSILTDNGFTKNGKYKLTLSKMMRK"
     gene            47004..47759
                     /locus_tag="TVB59_000046"
     CDS             47004..47759
                     /locus_tag="TVB59_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HEL1009001.1"
                     /translation="MALTALEIKDKTFKTKFRGYSEEEVNEFLEIVVDDYEALVRKNR
                     DNEAKIRELEEKLSYFDEMKESLSQSVILAQETAEKVKSSANAEATNLVSKATYDAQH
                     LLDESKAKANQLLRDATDEAKRVAIETEELKRQTRVFHQRLVSAIESQLSLSNSPEWD
                     ELLQPTAVYLQNSDAAFKEVVKTVLNEDIPEADDSNSFDATRQFTPEELEELQRRVEE
                     SNKELEAYQVQREEQASEPEVNLSETQTFKLNI"
     gene            48030..50828
                     /locus_tag="TVB59_000047"
     CDS             48030..50828
                     /locus_tag="TVB59_000047"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEL1009002.1"
                     /translation="MKLKETLNLGKTAFPMRAGLPNKEPQWQKAWDEAEIYKKRQALN
                     EGKPAFHLHDGPPYANGNIHVGHALNKISKDIIVRAKSMSGYQAPFVPGWDTHGLPIE
                     QVLAKQGVKRKEMDLADYLDMCRQYALSQVDKQRDDFKRLGVSADWDNPYVTLDPSFE
                     ADQIRVFGAMADKGYIYRGAKPVYWSWSSESALAEAEIEYHDIDSTSLYYANRVKDGK
                     GILDTDTYVVVWTTTPFTVTASRGLTVGPDMDYVVVRPAGSDRNYVVAEGLLDSLAAK
                     FAWESFEILANHKGSDLEYIVTEHPWDSEVDELVILGDHVTLDSGTGIVHTAPGFGED
                     DYNVGMTYGLEVAVTVDERGLMMENAGPDFHGQFYGKVTPIVIEKLGDLLLAQEVINH
                     SYPFDWRTKKPIIWRAVPQWFASVSDFRQEILDEIDKTTFHPTWGKTRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTKEVTDHVADLFQEHGSIIWWQKEAKELLPEGF
                     THPGSPNGVFTKETDIMDVWFDSGSSWNGVMNARDHLAYPADLYLEGSDQYRGWFNSS
                     LITSVAVNGHAPYKAILSQGFVLDGKGEKMSKSKGNIISPNDVAKQYGADILRLWVAS
                     VDTDNDVRVSMDILGQVSETYRKIRNTLRFLLANTSDFNPHTDKVAYAELAAVDKYMT
                     IKFNKLVGAINTAYERYDFMTIYKAVVNFVTVDLSAFYLDFAKDVVYIEAANSLARRR
                     MQTVFYDILVNITKLLTPILPHTAEEIWSYLEHEPEDFVQLSELPQAQTFDNQDTILE
                     EWEAFMTLRAQAQKALEEARHDKIIGKSLEAHLTIYASPEVKTLLTALDSDIALLLIV
                     SQLTISEEPAPENAVSFDDVAFTVARAQGEVCERSRRIDPTTRMRSYNAFVCDHSAKI
                     IEENFPEAVAEGFDSAAN"
     gene            complement(51306..51608)
                     /locus_tag="TVB59_000048"
     CDS             complement(51306..51608)
                     /locus_tag="TVB59_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEL1009003.1"
                     /translation="MRLINTTSSHPELVRNQLQNTDAHLVEVYSAGNTDVIFTQAPKH
                     YELLISNKYRAIKEDELEVIREFFLKRKIDQSIVIPGHSKTLHTNNLIEISFQTSV"
     gene            complement(51670..52119)
                     /locus_tag="TVB59_000049"
     CDS             complement(51670..52119)
                     /locus_tag="TVB59_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEL1009004.1"
                     /translation="MTVPIFGDKIDDQHYTARYGVYAVIPNSAKTEIILVQAPNGAWF
                     LPGGEIEAGESQLQALERELVEELGFAADIGYYYGQADEYFYSRHRDTYYYNPAYLYE
                     VTSFQAISKPLEDFNHLAWFLPIADAITVLKRDSHRWGVEEWQKKHH"
     gene            complement(52279..54531)
                     /locus_tag="TVB59_000050"
     CDS             complement(52279..54531)
                     /locus_tag="TVB59_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEL1009005.1"
                     /translation="MLCQNCNLNESTIHLYTSINGKQRQIDLCQNCYQIMKTDPKNPI
                     LGGYNGNQKAQQPSQNPFFDDFFGDLNNFRAFGQLPNTPPTQSGGHNGGGHNGYRPNH
                     TQPAQEANKGLLEEFGINITEMAKRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGE
                     PGVGKTAVVEGLAQKIVDGDVPQKLQSKQVIRLDVVSLVQGTGIRGQFEERMQKLMEE
                     IRKRHDVILFIDEIHEIVGAGAVGDGSMDAGNILKPALARGELQLVGATTLNEYRIIE
                     KDAALERRMQPVKVDEPSVEETITILKGIQPKYEDYHHVKYSQSAIEAAANLSNRYIQ
                     DRFLPDKAIDLLDEAGSKMNLTLNFVDPKDIDKRLIEAENLKTQATRDEDYERAAYFR
                     DQIAKYKEMQAQKLDEQDIPIITDKTIEAIVEQKTNIPVGDLKEKEQSQLVNLAADLK
                     KHVIGQDDAVDKIAKAIRRNRVGLGAPNRPIGSFLFVGPTGVGKTELSKQLAIELFGS
                     ADNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEQVRRNPYSLILLDEIEKAH
                     PDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKTEASVGFGAAREGRTNS
                     VLGELSHFFSPEFMNRFDGIIEFQPLSKDNLLHIVHLMLDDVNHRLAHNNIRLDVTQK
                     VKEKLVELGYDPKMGARPLRRTIQDYIEDAITDFYLEHPAEKDMRAVLTSNGHIIIKP
                     VVKSQAKQAD"
     gene            54813..55043
                     /locus_tag="TVB59_000051"
     CDS             54813..55043
                     /locus_tag="TVB59_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003105222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1797 family protein"
                     /protein_id="HEL1009006.1"
                     /translation="MESHLVRIINRLELMVTDGGNLKRNFERDGVVVAEVAFVNDPEN
                     GPVFILRDIEARESYSFDSIDLIAMEIYDLLY"
     gene            complement(55525..56463)
                     /locus_tag="TVB59_000052"
     CDS             complement(55525..56463)
                     /locus_tag="TVB59_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1009007.1"
                     /translation="MKKTIRKYSVCSAAIALATMASLGTAGNARAEDYTRLESYPDPA
                     ELIRDGLGDGEVRVYLHTLRQFMQTYLQNLELQAKKGGPQGPVGPAGPRGERGEQGPV
                     GPMGPRGDKGETGETGPKGEQGPAGPKGDRGERGEKGEQGQRGEKGEQGQRGEKGEQG
                     QRGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGE
                     KGEQGQRGEKGEQKPKGDQGKDTKPSAPKAPEKTPAPKAPEKSAQPKAPAPKSAPAAQ
                     KSTLPATGETNHPFFTLAALSVITSAGVLNLKKKKS"
     gene            56805..57488
                     /locus_tag="TVB59_000053"
     CDS             56805..57488
                     /locus_tag="TVB59_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEL1009008.1"
                     /translation="MDFTFLPKYWAYFNYGVLVTMMISACVVFFGTIIGLLVTLIKRS
                     HIKPLSWLVSLYVWIFRGTPMVVQIMIAFAWLHFNDLPIVGFGVLDLDFSRLLPGIII
                     ISLNSGAYISEIVRAGIEAVPKGQLEAAYSLGIRPKNAMRYVILPQAFKNILPALGNE
                     LITIIKDSALLQTIGVMELWNGAQSVVTATYLPITPLLFAAFYYLMITTILSQLLGCL
                     ERKLAQGGR"
     gene            57490..58227
                     /locus_tag="TVB59_000054"
     CDS             57490..58227
                     /locus_tag="TVB59_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL1009009.1"
                     /translation="MTETVISIRQLHKSFGKHEVLKGIDLTINQGEVVVIIGPSGSGK
                     STLLRTMNLLEVPTKGHISFEGVDITDKANDIFKMREKMGMVFQQFNLFPNMTVLENI
                     TLSPIKTKGMSRAGAEQRAYELLERVGLRDKAAAYPASLSGGQQQRIAIARGLAMDPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAKEVADRVIFMDGGLV
                     IEEGSPVQVFEAPKEERTKDFLSKVLS"
     gene            58671..60365
                     /locus_tag="TVB59_000055"
     CDS             58671..60365
                     /locus_tag="TVB59_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEL1009010.1"
                     /translation="MDYKAVYQEWLHNDFFNEEIKADLEAIKHDEAEIQDRFYKVLEF
                     GTAGLRGKLGAGTNRMNIYMVGKAAQALANTIIDHGPEAVSRGIAISYDVRYKSKEFA
                     ELTCSIMAANGIKSYIYKGIRPTPMCSYAIRALNCISGVMITASHNPQAYNGYKAYWE
                     EGSQILDDIANQIAVHMDAIERFEDVKQIPFEEALASGLTSYIDDSIEEAYKKEVLGL
                     TINDTDIDKSVRVVYTPLNGVGNLPVREVLKRRGFDHVFVVPEQEMPDPDFTTVGYPN
                     PEVPKAFAYSERLGQEVGAAILIATDPDCDRVALEVRAADGSYVFLNGNKIGALLSYY
                     IFSQRHARHNLPDNPVLVKSIVTGDLSKAIAAKYDVETVETLTGFKNICGKANDYDIT
                     KEKTYVFGYEESIGFCYGTFVRDKDAVSASMMVVEMAAYYKQRGQSLLDVLQDIYKEF
                     GYYNERQVALELEGVEGQKRIARIMEDFRNEPIEHAGAMSLKTIVDFKDGYLDFPKQN
                     CLKYYFDDGSWYALRPSGTEPKIKLYIYTIGETEADSIAKLDAIESACQAKMDSVS"
     gene            60477..61331
                     /locus_tag="TVB59_000056"
     CDS             60477..61331
                     /locus_tag="TVB59_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEL1009011.1"
                     /translation="MVQIIDGKALAQKMQAALAKKVESLKAEKGIVPGLVVILVGDNP
                     ASQVYVRNKERAALAAGFKSETVRLSDSVCQEELIELIEQYNQDDTIHGILVQLPLPH
                     HINDKSIILAIDPKKDVDGFHPMNTGHLWSGRPNMVPCTPAGIMEMFHDYGIELEGKN
                     AVIVGRSNIVGKPMAQLLLDKNATVTLTHSRTRRLADICRRADILIVAIGQGHFITKE
                     FVKEGAVVIDVGMNRDVNGRLIGDVAFDEVSELASMITPVPGGVGPMTITMLLEQTYQ
                     AALRRVSQ"
     gene            61328..62182
                     /locus_tag="TVB59_000057"
     CDS             61328..62182
                     /locus_tag="TVB59_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEL1009012.1"
                     /translation="MIIDQSFVARVVVPRQADSHKGSYGRVLLVGGLYPYGGAIIMVA
                     LACVHSGAGLVTVATDRETIAALHSHLPEAMAIAVDDEELLLSQLGMADLILIGPGLS
                     ENSRAARLFELVLAHVADHQVLVIDGSALRLLAKRAADVKQLRCPLVLTPHQKEWEAL
                     SGLAIDQQYDAANQAALKHFPRATILVAKSSATKIYHGNQIYRLRVGGPYQATGGMGD
                     TLAGMIAGIAVQFPESSLVAKVACATYLHSAIADELAKTAYVVLPTAISYELPRWLKA
                     ISTGQKLG"
     gene            62466..63806
                     /locus_tag="TVB59_000058"
     CDS             62466..63806
                     /locus_tag="TVB59_000058"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEL1009013.1"
                     /translation="MADYLSVTQLTKYLKLKFDRDPYLERVYLTGQVSNFRKRPNHQY
                     FSLKDEGAVIQATMWAGAYKKLGFDLEEGMKLNVVGRIQLYEPNGSYSMIIEKAEPDG
                     IGALALQFEQLRQKLAGEGFFDERHKQALPQFVTKVGIVTSPSGAVIRDIITTISRRF
                     PGVSILLFPTKVQGEGAAQEVAANITKANQREDLDLLIVGRGGGSIEDLWAFNEEIVV
                     QAIFESRLPVISSVGHETDTTLADFVADRRAATPTAAAELATPITKTDIVSWIAEQQS
                     RSYQACLRYIRQGQERVDKLSYSVIFRQPERLYDAYSQRLDRLTTSLMTTFKETLSGA
                     KQEHLILEHRLASVNVQARLERYQDRLATAHRLLIANMTNQYDSKLAGFERAQAALLS
                     LDTSRIIARGYALLKKDGVVAACVKDIKKGDHLSIIMRDGQLEVEVEDVNEKNI"
     gene            63784..63999
                     /locus_tag="TVB59_000059"
     CDS             63784..63999
                     /locus_tag="TVB59_000059"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEL1009014.1"
                     /translation="MSTKKIFEERLQELEAIVTRLENGDVPLEEAISEFQKGMVLSKD
                     LQKTLQAAEKTLVKVMQADGTELEMDA"
     gene            63999..64868
                     /locus_tag="TVB59_000060"
     CDS             63999..64868
                     /locus_tag="TVB59_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEL1009015.1"
                     /translation="MDKLTRINATIHQYYDRQSTVSADLEEAILYSVDGGGKRLRPLM
                     LLELLEGFGLALTDAHYAVAAAVEMIHTGSLIHDDLPAMDNDDYRRGRLTSHKQFNEA
                     TAILAGDSLFLDPFALIAGADLPADLLVQLIQQFSLASGTFGMVGGQLLDMKGEHQLL
                     DIQELSDIHANKTGKLLTLPFVAAGIIAEQSADVLSCLWEAGRLVGQAFQIRDDILDL
                     TASFADLGKTPQKDLAAAKSTYPSLLGLERSRAILEESLSQALAIFSRLEREEGFESQ
                     AIIKRIEGLRLNG"
     gene            64861..65688
                     /locus_tag="TVB59_000061"
     CDS             64861..65688
                     /locus_tag="TVB59_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEL1009016.1"
                     /translation="MAKERVDVLAYRQGLFETREQAKRGVMAGLVISAISGLRFDKPG
                     EKIDEGIELRLKGEKLKYVSRGGLKLEKALQVFGISVQDKVTIDIGASTGGFTDVMLQ
                     AGARLVYAVDVGTNQLVWKLRQDSRVRSMEQYNFRYAKLADFSEGQPAFASIDVSFIS
                     LSLILPTLHCILQEGAEAVALIKPQFEAGREQIGKKGIVKDRLIHEKVIKQVADTALN
                     CGFIVKGLDFSPIQGGHGNIEFLAHLVKGKGSKAIDDQLIQSVVSSAHKEFKQHEKE"
     gene            65675..66145
                     /locus_tag="TVB59_000062"
     CDS             65675..66145
                     /locus_tag="TVB59_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEL1009017.1"
                     /translation="MKKSERLDLIKKMVLSHEIETQHELLKLLADYGLELTQATISRD
                     MNEIGIVKIPSGTGRYVYGLSQDSGKRVVQRPASIKKTILEMSEKTAGLEQHIHLNVV
                     PGNSKLIKRYLMTDFSGQLFSLIADDDSLLLIAKSEADADHIRQELSLWMQGLV"
     gene            66163..67824
                     /gene="recN"
                     /locus_tag="TVB59_000063"
     CDS             66163..67824
                     /gene="recN"
                     /locus_tag="TVB59_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEL1009018.1"
                     /translation="MLLEISIKNFAIIEEISLNFENGMTVLTGETGAGKSIIIDAMNM
                     LLGARASTEVIRHGADKAEIEGFFSVDANPHLAAVLAESGISMEEELILRRDIFANGR
                     SVSRINGQMVTVSTLKKLGQFLVDIHGQHDQEELMRPQLHQHILDSFGDEAFDQLKQS
                     YQQIFDRYKALRRQALEKQKNEKEHQARLDLLAFQIGEIEAADLVRGEDDLLNQERQR
                     LLNHKKIADTLTSAYLSLDNEDFSSLSQVRSSMNELLSIEDLAPEYQLISAGVSEAYY
                     ILEEVTKQLSDTIDQLDFDAGRLQDIELRLDSINSLTRKYGGGVNDVLDYYANITKEY
                     QLLSGDDRSSDELERELKVLEKQLVMTASQLSDKRHALALELEADIKAELRELYMEKA
                     DFKVHFTRSKFNREGNESLEFYISTNPGEGFKPLVKVASGGELSRLMLAIKAAISKKE
                     DKTSIVFDEVDTGVSGRVAQAIAKKIYKIGSYGQVLAISHLPQVIAIADNQYFISKES
                     KEESTVSKAKLLTQEERIEEIAKMIAGADVTETARNQARELLGKD"
     gene            68045..68917
                     /locus_tag="TVB59_000064"
     CDS             68045..68917
                     /locus_tag="TVB59_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL1009019.1"
                     /translation="MLKKRMGLASLLVLMTFVYQCCSVTAEQYSDTEVEVLQISEEKS
                     QIMENQEALKDLTTSSDQLKKEALKPKEAATNKSKQEASTVYLAEDDPVTIDSSDEES
                     NQDIIADSVPDLVIKGDQVDVSEVMVSVKEDSSKVAKQRTDAAQRYSIAKHQLTQKLE
                     AFNAATDQLLTMIAKKSDLTGQYYVVGHSLGEMLAAQNEKKLAEQLVMQQKHKKGLGS
                     SVTILDELGRVISDISGHKGMLPFNRKISFKVHQVRYDLPLTGDRTVLPAQLAGLLLL
                     LIGLMLPKVANKKS"
     gene            69055..69906
                     /locus_tag="TVB59_000065"
     CDS             69055..69906
                     /locus_tag="TVB59_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL1009020.1"
                     /translation="MELKMGTIKIVADSSMTIEPELIKSLDITVVPLSVMIDSKLYSD
                     NELKEEGQFLQLMRASKSLPKTSQPPVGLFADIYERLVKEGATAIVAIHLSPALSGTI
                     EASRQGAEIAAAPVTVLDSGFTDQALKFQVVEAARLAQAGASLEEILEAVEDIKRKTE
                     LYIGVSALEHLVKGGRIGRVTGLLSSLLNIRVVMEMKNDTLQTLVKGRGNKTFTKWLD
                     SYLAENSQRQIAEVAISYAGQRDFADSLKKTIATVFDGPITVLETGSIIQTHTGEGAF
                     AVMVRYE"
     gene            69899..70741
                     /locus_tag="TVB59_000066"
     CDS             69899..70741
                     /locus_tag="TVB59_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HEL1009021.1"
                     /translation="MNKRGFLGGLIFFFSVFALSFVILAVLIPKSDPQLKKSDFLKNK
                     KISLNYIAIGDSLTEGVGDLTNQGGFVPLLSGDLGDYFNATVNTENYGVSGNTSQQIL
                     TRMTENKEITEQLKKANLMTLTVGGNDVLAVIRKNLANLKVSSFKKPARQYQERLRKI
                     LDLARKDNQDLPIFVLGIYNPFYLNFQELTEMQTVINDWNKKTQEVVDDYDHVYFVPI
                     NDLLYKGVDGKEGIVQSTGEQTTIVNDALFSGDHFHPNNTGYQIMSDAVMETIRKNGK
                     EIKP"
     gene            70719..71306
                     /locus_tag="TVB59_000067"
     CDS             70719..71306
                     /locus_tag="TVB59_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HEL1009022.1"
                     /translation="MEKKLNLNWWKWAFLLLLAFNAAFLAVIGSRIIQIREPKSELIN
                     QKAAKNIKIGTLTTTKEQLNEAVVSYLKDFQTEKMTYKVYATSSTILFEGTYQLLGYE
                     VPLYIYFQPHRLTNGAIQLQVLSFSVGTLSLPEKDVLQYLKSSYKLPKFVEVLPKQSA
                     IIINLQQLENDANIYLKAQKIDLVKDDIRFDIYKK"
     gene            71404..71679
                     /locus_tag="TVB59_000068"
     CDS             71404..71679
                     /locus_tag="TVB59_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEL1009023.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVDAVFSAIEAFLAEGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIAASKVPAFKAGKALKDAVK"
     gene            complement(71740..72444)
                     /locus_tag="TVB59_000069"
     CDS             complement(71740..72444)
                     /locus_tag="TVB59_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosyltransferase"
                     /protein_id="HEL1009024.1"
                     /translation="MLVVQPSTIKAQSYDEGQTVVFEPYGNSFKPYYKFSEPDVTKYI
                     ITNRWRSQTAFTEAEKKMMYQYTYASASPINLALEQVMGDTSQLDAQLQQSVALLDSA
                     THKLTIPWNIIVYRYVYETFLTELGTSEEELARYYHDKTFDPQILSAIKPGTHYTKQG
                     FMSTTAIKNAAMPHRSVELRIQVPQGSQAAFVQPYSFYPYEMELLFPRQCTLEIIGAN
                     LSDDHTRLLIETRLLP"
     gene            complement(72755..73963)
                     /locus_tag="TVB59_000070"
     CDS             complement(72755..73963)
                     /locus_tag="TVB59_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1009025.1"
                     /translation="MRKNDYQLLASRAINKIGNTVYDYSNSSGIAGLGATGRQYLGYY
                     QLAEGLISLILNPIGGAIADRYKRRQLLLWTDAIGAISCGLLALIANPTIMLYGLITV
                     NALLAISYAFSGTAFRAYVVTLVETERLVHFNAQLEIVSQIISISSPMLAFLVMDCFG
                     IKTALALDSISFLLSFLCLYTIKDKERHITKQSSQGNRLQLLTDIKEGLQFIYHDNDI
                     FSLLIIASLVNFFIAAFNYLIPFSNQLLGSQSSYASLLSMGALGAILGAFMANKLFKN
                     NQQSLLLSLGLSGLGMLLITAMALLKLPVIVIALGNLWFECFLTIFNIHFFSIVQKKV
                     PEALLGRVFSSIVTTAILLMPLATTIMTCIPASVHLATFAVIGIGIMATASLAYYCNY
                     RQSSKKKPFI"
     gene            complement(74018..74911)
                     /locus_tag="TVB59_000071"
     CDS             complement(74018..74911)
                     /locus_tag="TVB59_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1009026.1"
                     /translation="MTNHQLGKAFRSIRQNRNITLQQLASKDVSLSQLSRFERGESDL
                     SVTKFLTALDSMQVEISEFMDIAANFKQTEQIQFMSQLIKLEYARDIEGFKQLQKQEL
                     AKHQADPDTNRYYLNSILLQGFICKCNPSIPFPKAYLDEVTDYLFRTESWHIYELILI
                     GNLYLFIDIPLLDKMGKEILNNHTYYESISTNKHLVTITLLNIWETCIHRHQLDYARY
                     YQKQILALLNNETKLYEKTIFLFLKGLEDYQRGQCLSGIKDMTTAISIFESLDCPHLA
                     HNYQKDFERFVASSSLICKKT"
     gene            75280..75453
                     /locus_tag="TVB59_000072"
     CDS             75280..75453
                     /locus_tag="TVB59_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009027.1"
                     /translation="MPIIVILGLAIFSVVKVIIFLCFYKAFEKKQLKKLEQDQKETKQ
                     AIDQEESKKAFPF"
     gene            complement(75498..76433)
                     /locus_tag="TVB59_000073"
     CDS             complement(75498..76433)
                     /locus_tag="TVB59_000073"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEL1009028.1"
                     /translation="MVSTATKIATFAFNNCLMNAAGVYCMTKEELLAIEASEAGSFVT
                     KTGTLAPRQGNPEPRYADTALGSINSMGLPNHGYQYYLDIVTEMQKDQASKHHFLSVV
                     GMSAEETETILKAIQASDYQGLVELNLSCPNVPGKPQLAYDFEATDQLLKKIFSYYTK
                     PLGIKLPPYFDIVHFDQAAAIFNQYPLAFANCVNSIGNGLVIDDEQVVIKPKNGFGGI
                     GGDYIKPTALANVHAFYQRLNSSIQIIGTGGVKTGRDAFEHILCGAAMVQIGTALHQE
                     GPAIFKRITKELQDIMAEKGYQTLDDFRGQLQYKP"
     gene            76676..77371
                     /locus_tag="TVB59_000074"
     CDS             76676..77371
                     /locus_tag="TVB59_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003084158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEL1009029.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIAFDLAFTSVLKRAIKTTNLALEYSDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPDMAKDDEHSAHTDRRYAHLDHSVIPDAENLKVTLERAL
                     PFWEDKIAPALVDGKNVFVGAHGNSIRALVKHIKQLSDDEIMNVEIPNFPPLVFEFDD
                     KLNLTAEYYLGGE"
     gene            77480..78001
                     /locus_tag="TVB59_000075"
     CDS             77480..78001
                     /locus_tag="TVB59_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEL1009030.1"
                     /translation="MKVKERREAITDRLSQAQEAISATSLAKALGVSRQVIVGDIALL
                     RAQQLDIISTPKGYILSNALFSHHYSARIVCQHGPEQTRQELELILAHDGIVTNVEVE
                     HPIYGMLTAPLNIKSSADINNFIEKLGASKAELLSSLTEGLHTHLLSCPDQEAFEEIK
                     RDLAAAGILYGEQ"
     gene            78396..78935
                     /locus_tag="TVB59_000076"
     CDS             78396..78935
                     /locus_tag="TVB59_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009031.1"
                     /translation="MTKKPTQLIAYSSILVAFAILIPMIMPIKLIIGPASFTLASHLP
                     LFLAIFISIPVAILVGIGTGLGFLLAGFPMIIVMRAFSHVLFAAIAAFMLKRQPKWLE
                     TPLRTFVFGIIANVIHGLAEFLVVYLMTATAATDLSYFWSMLMLVGFGSLLHGMVDFY
                     LALFIWRFLRQKGHLSVTS"
     gene            79074..79844
                     /locus_tag="TVB59_000077"
     CDS             79074..79844
                     /locus_tag="TVB59_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEL1009032.1"
                     /translation="MKTPEQILAATITIGEHKVAKPFLAKAILGFIGGAMISLGYLLY
                     VRIAASGLETFGAFSSILGACAFPIGLIIILMAGGELITGNMMAVSAAFFAKKIKAKD
                     LMANWLVITLFNILGALFVAFVFGHFLGLTATGSFKEEVIEVAHAKLAATPLQAIVSG
                     IGCNWFVGLALWLCYGASDATGKLLGTWFPVMTFVALGFQHSVANAFVIPAAIFEGGA
                     SWIDFATNFALVYVGNVLGGAIFVSLFYYKAYDHSKEA"
     gene            79956..82010
                     /locus_tag="TVB59_000078"
     CDS             79956..82010
                     /locus_tag="TVB59_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HEL1009033.1"
                     /translation="MASWIKKKKASIPRRIHLLFLVIVFLFVALILRLAQMQIYEKDF
                     YKAKLTASTVYKVKSSMPRGTIFDRNGKVLVSNRIKDVVTYTRSPKASAKDIKALAHQ
                     LAAYISYPEAKVTVRAKKDYYLADPEAYAKTVQALPQKDKVDRFGNKLVEAQIYQNAA
                     ASLKETDLTYSDQELKVIAIFNQMNAAAVFSTVKLKTSALSEQDIAIIMANKSKLPGI
                     SVGTDWERQVEETSLAAIIGRVSSEEAGLPKEEAKAYLKKGYSLNDRVGTSYLEKQYE
                     EVLQGKHEIREIKTSRSGEVISDKIVEKGQMGRNLKLSVPLDFQQGVEQILNQHFQTE
                     LKNGQAAYSEGIYAVALNPNTGAILAMAGLSHNPKTGELQKDALGTITDVFTPGSVVK
                     GATLAAGWQAGVIQGNQVLIDQPIQFGGSQPINSWFTSGQHPITASQALEYSSNTYMV
                     QVALRMMGQDYVTGMTLANTGMKETMKKLRAAYAEFGMGVATGVDLPGESSGYLIDQY
                     NTANVLTEAFGQFDNYTTMQLAQYVSTIANGGSRLAPHIVEGIYQDNDQSGPGKLSKA
                     IETTLLNKVHLAADSLAIIQDGFYQVVNSGSGYATGRALAGGPVTISAKTGTAETYAK
                     DKNGQALSTFNLNVVAYGPSASPQIAVAVMYPHATDSLAKAHQYVAKDIINLYMKMYK
                     NQ"
     gene            82022..82618
                     /gene="recR"
                     /locus_tag="TVB59_000079"
     CDS             82022..82618
                     /gene="recR"
                     /locus_tag="TVB59_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEL1009034.1"
                     /translation="MLYPIPIAKLIESYSKLPGIGVKTATRLAFYTIGMSDEDVNDFA
                     KNLLAAKRELTYCSICGNLTDDDPCHICTDSSRDKEIILVVEDSKDVSAMEKIQEYHG
                     YYHVLHGLISPMNGVGPDDINLKSLITRLMAGEATEVIVATNATADGEATAMYISRLL
                     KPAGIKVTRLARGLAVGSDIEYADEVTLLRAIENRTEL"
     gene            82766..83812
                     /locus_tag="TVB59_000080"
     CDS             82766..83812
                     /locus_tag="TVB59_000080"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEL1009035.1"
                     /translation="MSKQTLILLYGGRSAEREVSVLSAESVMRAVDYTKFFVKTYFIS
                     QTGQFIKTQEFSSRPTLTERLMTNDTIRLEQQIRPSDIYEEGAVVFPVLHGPMGEDGS
                     IQGFLEVLKMPYVGTNILSSSVAMDKITTKRVLESAGIPQVAYTVYIEGQDLDRCLAE
                     TEAVLSYPVFVKPANMGSSVGISKAESEEELRAAILLALTYDSRILIEQGVLAREIEV
                     GLLGNTDVKSTLPGEVVKNVDFYDYQAKYIDNEITMAIPAAIDESAMTSMRTYAETAF
                     KAIGACGLSRCDFFLGQDGQIYLNELNTMPGFTQWSMYPLLWEHMGLSYAELIEELVR
                     LAQEMFEKREGHLI"
BASE COUNT        23630 a        15813 c        20143 g        24418 t
ORIGIN      
        1 tcaggggggt gagaaaaaag acattagcta catcgagcaa gagggcgatc tgtctgccct
       61 atttcaatca gagacagact taagcattaa aaagaaacag cagcatcgaa aagaaactag
      121 tcagacgacc aagaatcacc tatttatgac tcatattgat agtgacaacc ttgttgcaag
      181 gtatcagcca ctcttattta acccagagca gcgtctggca gcaacagatg accagtatgg
      241 tgttttgctc gctcaaaaaa ctatcggcat cacttggcaa atgctggcca tacttcttgt
      301 gggagctgta ctgactggct attctctgac tagagggcga ttatcaaggc aaaaacacaa
      361 aagacatcac gagtagaatc gtctgtcaag agtatctact cactgaaaat agagggctag
      421 cttaggagac ttcctaatgc tgcatttata agaaaaggct ctcagctgtt ttgacagtat
      481 tgggcaaggc cttagggcct gtagcaaata tgaagagcag ctttgatcag caggtagcaa
      541 gtcagtcaat acaaatgctt gaaagcctac ctgctgagaa aagtgtgtgt tctacgatac
      601 tttagtgatg tgaatcacct caagaggctt tagctagctt ggcaggtgat gtcaggtgac
      661 atggaaactt atcaggaaag ggctaatttt tatggagaat tatattagta tcagtcttga
      721 ttgctcgcat ttttttcaca ggaatttgat ttgcgggtac caaggacaat gacctttaag
      781 gagctattac aaatcgtatc agatgcttat ggtttgggat ttcaggtggt aaatcccagt
      841 gctagaaatg agcaaggtgg tcagctgatg acaagcacca gtcgcatgga taccctaaaa
      901 aatggtgcac tgttagtatt ggaaaattta taaacatgga gaaaaagatg aaaacaataa
      961 tacgtgagct attggttgag gatgttaaag gagatgctga ggttgcttat accttactag
     1021 cttctgagca ttctcttttt gttccttcca agttagaaca ggctttcgac aagctgattc
     1081 tagaggctag cattgatgac atgtatgact ggtcagccct agaggcgatg attgttgagg
     1141 aaaagctaag gcatttgcta aatcttagtg agctgtttga tcagctcttg gactcaaagt
     1201 tcacctacag ctttacacca gataatctgg tctttaaccg taatgcagag ccacagttga
     1261 tttttcgggg aatcaaggat caggttcctc cttaccagcc gcttgagcgt gaggtctttg
     1321 tgaatacact gaaatgtatg acaattgcct tgcttgataa aaagaccagc tatgacgctc
     1381 tgatgggtgg caagcttccc ttttacaaag gcaatctttt ttgcgaagca gtggccaagg
     1441 ctgaggcgct gcaggagttg caggagcttt tagcgacaaa gtaccatgag gagcaaaaag
     1501 acaataaaga gcatttttct cgtgttgcta acaagacgat atcgcgcttg aaattgacca
     1561 ccatttgttc atcagtgctt gctttgttgt ctttggcggg cgttctttat tttctattgt
     1621 ttgctatgcc ttatcaggaa atggttgcta gtctgcgtat ggcttttatt aatcaagact
     1681 attctaaggt tatcacaaca gcgaagcata cagacagtaa ggccttaagc cagggtgata
     1741 aatatattgt ggcttactct gtcataatga cagagcctct aacagacaag caaaaggagg
     1801 aattaagtaa aatatcgaac cagtctaatg aagattattt acgctattgg gtgctgattg
     1861 gtcaagcaag gatagatgat gccatggata ttgcgagcta tctagacgac ccgcagctct
     1921 tgatgtatgg cttgactaag aagattgatg atgttcagcg agatcctaat ctgacagcag
     1981 aggcgcgtac agagcagctt aacagctata agagcaaatt agacgagctc aaaaaggcct
     2041 acctgacgcc taaagaggaa aaagcagcag gctctagcag tgacaaggag tgacggagga
     2101 atttatgaca taccttattt atgacgacaa tgcctatcac ctttattcgg ataccgttta
     2161 tcagttgggg ccttcatcag ggtctgatat tttcctgccc ttgctggagg atattacctt
     2221 atcagtggag ggatcaggtg ttgtcctact ggaagagagc tacagcactg gtaagcattg
     2281 tgttgctctt tctgatgagg ttacagtgac cttacttatt cttgaagctg tcactaaata
     2341 cctgctgcca gactcctcgc tttacatttc aggagagact accgcagcac ttcaattgct
     2401 tgattaccct agtgagctgg tgctgaccct agactctgat tctgccagct gctatagccc
     2461 ggtgtcttat tatctaaatg gtaaatggac gaaaggcaag cagcctctta aagcatctga
     2521 tgaacttgtt ttttcagatg gcttagtgct tagttttcag gatcagctgc tatcgattca
     2581 gtccttgtat gctattcaga cagcattgct gcctcttaca gaggcagtag ctgaggatag
     2641 agccagtgaa tttcatcgtt ctcctaggat tatcctgcgt gagcctgagg gaaaggtgac
     2701 gattgcttct gtacccacag atgatgaagg gaaaagacag tctttattaa agctgatcat
     2761 aacgcccctt gcgatgattg tctttacagg gctctcttat gtctttttcc gaggtggggg
     2821 aatgctcatg atgatgatgg gaatgtctgt gattacgatt ggaagctcca ttcattctta
     2881 tttttcagat aaaaaatggc ataaagaagc ccagcagcaa aaaatcaagg attatctagc
     2941 ctacttggat accaagtatg tggagctagc aggctatcgt gaggagcaaa tcgaagcact
     3001 gctgtatcat taccctaata tgacgactat tcttgaaatg gcacaaaaaa cagatcgccg
     3061 tatttatgag aaggctccat atcattttga ctttttgacc taccgcttgg ggctaggtga
     3121 tactccagcc agctttcaca ttgattattc agattctgag ctgaccaagc atcatgaaaa
     3181 ggcaaagcaa agggttcaag agctgattgc ttattatcag gtgacagcac aggtgcctat
     3241 ccaaaatgcg attgccagtc caatcggtta tattggagca cgcaaggtcg tgattgagca
     3301 ggttcagcag ctgatgatgc agatcgctac cttccatagc tatcatgatg tacagtttat
     3361 tcctattttt cgagaagaag agctgccatt gtggaattgg agccggtggc tgcctcatac
     3421 taagctaaag gtgctaaata gtcgtggctt tgtttatagt cagcgaacac gtgaccaatt
     3481 gttgacctcg ctttatcagc tgatcaagga gcggcaatta gacagtgagc aggataaggg
     3541 gacagaaaag caatacactc cgcattatat agtgctgatt actgacatga gcctcatgct
     3601 tgaccacaat atcatggaat acatcaatga ggatttgtct catctaggca ttcattatat
     3661 ttttgttgaa gaggtcattg aaagtctccc tgagcatgtc aaaacagtta ttgattatcg
     3721 tggagataag catgctcagc tcattttgca ggaggggctc tacctcaata aggcctttac
     3781 cccacttcaa cccttatcta tgaaggataa ggaggtcttt gctagacata tggcagggat
     3841 taatcacgtt gagaccttac gcaatgcgat tccaaatagt gtgacctttc ttgaaatgta
     3901 tggcgttaac aaggtcgagg agcttaatct cttaaagcgc tggaaggaaa atgaggctta
     3961 tcagacaatg gctgttccgc ttggggtgcg tggtcgtgat gacatcttgt acctaaacct
     4021 tcatgaaaaa gcccatggac cgcatggctt aattgcagga acgactggat ctggtaaatc
     4081 agagctggtt cagtcttata ttttgtcgct ggcggtgaat tatcacccct atgaggttgc
     4141 ctttttgctg attgactaca agggtggtgg tatggccaat ctctttgctg atttaccaca
     4201 tgtcgttgga accattacca acctagatgg caatcaggcc aatagggctt tggtatcgat
     4261 taaggcagag ctgaaaaagc gtcagcggat tttccttgaa aatgatgtca atcatattga
     4321 tcaatacact aagctattca aggaaggacg agttaaggag cccctcccac acctgttaat
     4381 catcagcgat gaatttgcag aattaaaggc caatcagcca gaatttatgg acgagctggt
     4441 ctcaaccgcc cgtattggtc gttctcttgg tgttaagctc attttagcaa cgcaaaagcc
     4501 aagtggtgtc gttaatgacc agatttggtc gaatgcgaag tttaaaattg ccttgaaggt
     4561 tcaagatgtt gcagattctc gtgaggtgat taaaacccca gatgcagcag agattactca
     4621 ggttggtcgt gcttatctcc aggttggaaa caatgaaatt tacgagctgt tccaaagtgc
     4681 ctggtctgga gcagactaca atccaaaagg acgacatacc attcagcatg agacaacggt
     4741 ctatgaaatc acagctaatg gtcaatacca agcgattaac aaggacctta gtggacttga
     4801 caagaagaga gaagcaaaat ccatgccaac agagctagat gcggttgtag cagaggctca
     4861 gcagctcttt gaggacctgc atattccaaa ggtggccagt ccttggctgc cgcccctttc
     4921 agaaaaaatc tatgccagtg atttacagtc cacgcatttc aaggactatt ggggacagac
     4981 acaggacttg cagcctgttt tgattggcta tcaggacatt cctgaacgcc aagagcagtc
     5041 cccactctat tttcatatgg aaaaggctgg gcatatcctc ttagtgtcta gtcctggctt
     5101 tgggaagtcc accttccttc aaggctttgc tttagatgtg atgcgaaagc aaacaccagc
     5161 acaggctcat ttttacctct atgattttgg gacaagtggc ttgattgcgc tttctgattt
     5221 tccacatgtg gcagattact ttaccctaga tgagacagac aagatcatga aatcacttcg
     5281 ttatttaagt gaagaaatca agacccgtaa gcatgcccta tctaaggcta aggcaaccaa
     5341 cctcaatcag tacaatcaat tatccaagga taccttcccg gctctttttg tcatcattga
     5401 tggctttgat agtgtcatgg acgcaccatt tgtagatgct gtctacaatg tcttaaacgt
     5461 tattgcgcgt gatggggctt ccttgggaat gtaccttgtt gtgaccttat caagacttaa
     5521 taccatgagg ctacagctgc agtctaactt taagaccaag ctatccctct tcttgtttga
     5581 taatagtgat ttatcaagtg tggttggtcg ctcaaatatc ccactagatg atatcaaggg
     5641 acgagctatc atgaaacgtg acgacattat ccaatttcag attgccttgc catatagcag
     5701 tgagtactat acagattata tggcggaggt aaaaagagag gtcgaggcga tgagggctgt
     5761 ttatcaaggt gctttgccag cggctattcc aatgctgcca gaaaaggtta caccggatat
     5821 gatagcagcc atgtcagact ctgctcagga ttttgtgatt ggtttggagc gagaggacgt
     5881 tgttcctgct ggctttacct ttaaaaagtc aatactgatg gcctctgata gcccagcctt
     5941 tgtggctaac tattataagc tgcttgattt tcagttgcag cgtctggctg accagtatcg
     6001 tacggttatt ttagatccta gtcagcgtat tgcaaggcaa ttctttgagg atagtcaacg
     6061 ctttagcaca gccttagatg ttggagacac tctaagggct attgtagagg actttaaaaa
     6121 gcgtcttgca gcacctggtc aggattatca aaaatggtta gttgtgattc ctgatattgc
     6181 agctacagcg ctggcagcag ggattagcga ggaagacttt aaacagcttg tgaccgaggg
     6241 cagccagtat ggggtcacgc ttatctttgt cggagcttat caggatctgg tcaataatac
     6301 ctatgataat tttgtgaagc ttgcaaatca gctcattgag caggtctttt taggcatgcg
     6361 gatcagtgac caaagccata cacgatatgc ttatatcagc aatgagcctt cacttagacc
     6421 gacccagggc tatatcctat acccagaagg ctatgacttt attcaattat tagagattta
     6481 gaaaggaaca aagatgtcaa cagttacgat gcttccactt ggtagtattg tcattttaaa
     6541 gggcaatact aagaaaatga tgattattgc gcgtgtgatc gcagctccaa tcaaagggga
     6601 ggtttaccgc tttgactatg gtgcctgcct gtatccggag ggcatgatgg gggatagttt
     6661 gatttacttt aatcatgacg atatttttaa gattattcaa gaaggctatg ctgatgatga
     6721 caatgctctg atgttagaga cgatagcaca ggctttagca acaacggaca ttccaaaagg
     6781 agatgtttca gccttaaacg atagaaagac tgttgaggac tagcttatgg ggcaagttga
     6841 ctacaatcat atcaatcagc ttcaacgtca ggttgaccag cacagggcca gtctatcaac
     6901 ggctacagca gagatagcgt caatagacga aaagctagag cgcttgcgtt gtgccaaggc
     6961 ttctgttgga gcgattcaag gagatgttca tcagatcaag gtctctgtga tggctaagag
     7021 ggatcagcct gattggaagg gagaacgcaa ggaccgcttg atgtcgagct gggaggagtt
     7081 ctctcatgac tatcgccact ttcagctgga gctagatgct tattacgatg ccatttgtga
     7141 tacgataaca cgcttggaga atcaaaaata tgagcagcaa gggcttatcg gctggtgtca
     7201 gagcatgatt aatagcttgg gaaatgagat tgaaaagcta tttcatatta gggagggcta
     7261 gcatgtttgg tgttattcaa ttatctgagg ttgtgtttgg ggcgcatgtg ttaagcctga
     7321 ctgctgctaa ggctagcttg tctgatgtca aagctagctt tcccagccat cagtcatcaa
     7381 gtaaggtgct agatctgtat cagtcagagt ttgaagcact ctctcagctt gttgctgcct
     7441 atgctaggct tttggaaaag gatattgcct tgattgccga ggctggtcaa gaattagccc
     7501 taacagataa gcagttggga caagctatag gatttaggtt acaataggag gagggtatgg
     7561 gatataagat tcactttgaa gccatcagtg ccgcccaaca aagcactcaa accacgatca
     7621 gtgcttgggg agaaaggtcg tcttctcttt tatgatgttc aaagcaaggt aaatactttt
     7681 cttgaagttg tcaacgtttc tgaatccaaa agcattgcgc ttgatacctt tgataaattt
     7741 gttagttgct tcaagcttgg cgttagaata aggcagttca atggcattga tgatatagtc
     7801 gttatagcgt ataaaggtgt ttaaagtcgt tttgaaggtg tgattgagat gaggcaaagc
     7861 atcttgactt aacccaaaga agagctctgt cttcttttct tgcaagtgaa aaagaagtca
     7921 ttggtacaga tcataatagc cttttaactc agggattcgt ttgaaaatct tattgagaca
     7981 ttgtctagga gttaatgttt ctctaaaggt cctagagtag aaagtattaa gagatagttt
     8041 ccagttatcc tttagactaa gcttccaata gtatttaaga gcccgatatt caagagcttt
     8101 cttatcaaat ggcttcatga gttgaatgcg agtttgattg agcgctctac tcatgtgcta
     8161 cacaatgtgg aagcgatcga gaacaatttt agcttttggg agtgaactag tccagtggac
     8221 taattcagcc tgagcttaaa aatagaagag cgaagggttt aatgagagga atgtaacttc
     8281 ctgacatatc gacagtaaca actttgccct tatttctagc ttctttggag tacttaaaga
     8341 agtgatttcg aatggttgtt tgacatctgt tattgcgaat gataatgatt ttcttggtgt
     8401 tgaaatcctg agcgataaag gctagtttgc ccttttgata agagaattcg ttccaggaaa
     8461 gcacctcagg taaggtggtg taatcctctt taaagtgaca ttgcttgagc ttatgataga
     8521 cggtagaggt agagatagcg agtttagcag caatatgcgt aaaagcttct ttattgagca
     8581 atagctgaga gatcttctgt ctaactggtt cagagatttg gcaatttttc ttcacgagat
     8641 tggtttcaga gacagctacc ttccgacagg tttgacattg aaacctgctc tttttcaatc
     8701 gaataaggct agggaagcca ccgatttcga tgaaagggat tttagagggc ttctggaagt
     8761 catacttaat ctgagctctc ttacagtgct tacacttagg aggttgatag tccaatgtag
     8821 cgatgacttc gatatgtgta tcatgctgga tagccttatc gaaggtgata ttttgatctt
     8881 taattccgat gagtagtgtg gtatgatgaa tctgttccat aagacacttt ctaatgatgg
     8941 tctggtcgct tttcatgata agccttatgg gactttttgt gtactcaaaa gccctataat
     9001 ctccatagtg gacttaccca ctacagaaat tataaagccc taaaaaccaa tctgaggttg
     9061 ttgcaacagg attggttttt tcttgtgatt gcagatcaga cttttcaaaa gaacaagcac
     9121 attatctcag ctagactggt gcttgatagc tcctgagccc ttgtttgctg tagttgatag
     9181 gactttgctg atggcctagt caggcatatc gtatcaaatt caagtttttt catgtcactg
     9241 tctatagttt gtctgcccta ctttaggtag aatagaggta acttaagaga ggagtttatt
     9301 atggaattaa cgatgctttt gatggtttca gttttcattg cagggctgtt atcattcttt
     9361 tccccttgta tctttccagt tctgccggtg tatttaggca ttttgttaga ttctgatgat
     9421 tctaggtcta ttactatttt tggcaagaaa ctatattggt acggtattgt taagaccctt
     9481 gcttttattt caggtctatc taccattttt atcattttag gctatggggc tggtttactg
     9541 ggtaatattt tatatgctgc ttggtttcgc tacctacttg gtgcctttgt gattttgtta
     9601 ggtattcatc aaatggaaat cgtaaccatt aagaagctgc aatttcaaaa gagcgtagca
     9661 tttcaaaata agaaggaccg caatgctgtt ttaaatgcct ttttgctggg aattaccttt
     9721 agctttggtt ggacgccctg tgttggacca gttcttagct cggtgcttgc cttagcggct
     9781 tcaggtggca gtggggcttg gcagggtggc ttcttgatga ttatttatac cttgggctta
     9841 ggcctaccat ttttactact atcttttgct tctggtattg tgttgaagca ctttaataaa
     9901 ttaaaaccac acattcctct attgaagaag ttaggtggct tacttattgt tataatgggc
     9961 ttactgttga tgacaggaaa tctcaatagt ttatcaggtt tatttgaata aaggagaaga
    10021 aacaatgaaa aaaacaacat ttttaacaac aggcttagca tgtcttgctt tattaactgc
    10081 atgttcggcg aaggataaaa tggccatgaa tgatagtaaa aaagaccata tgaccaggac
    10141 cgatgacaaa tcaaagatga aaaaggatca aaaagacaag atgtcagaca agaaggatat
    10201 gatgtcagat gacaagcaca tgtcagatgc tgacaaggct agtaagaatg atgggcaaat
    10261 ggctccagat tttgaattaa agagcattga tggcaagact tatcgtttgt cagattttaa
    10321 aggtaagaag gtttacttga aattttgggc ctcatggtgt tctatctgct tatcaacctt
    10381 aggtgataca cagtcattag ctacgatgaa ggataaggat tttgaggtct taaccattgt
    10441 ttcacctggt catcagggtg aaaaatccga ggctgatttc aaaaaatggt ttgaaggaac
    10501 agactttaag gatttaccag tcttgctcga tccagatggc aagctgctag aggcttatgg
    10561 tgtgagatct tatccaactg aaatttttgt tggcagtgat ggtgttttag ctaagaagca
    10621 tattggttat gcaaagaaat cagagattga aaaaacctta aaggagatta aataagcaaa
    10681 ggaggctgtc tcatggaaca caaatggaag ttattgctac tcgtttttgg agccttagta
    10741 tttttaggag gtgttttgat ggtctttcaa agaggctacg ctactagcta ccataataat
    10801 caggtcaagc tgcctgccaa agggacgtct cagctcaaga agactgctaa tgccaagctg
    10861 cctgagaaga aaaaggagat ttaccttgca ggaggctgtt tctggggtgt ggaggagtat
    10921 ttttcaaatg ttgatggtgt tctagatgct gtttctggct atgctaatgg tagaggcgac
    10981 acaacctctt atcaattgct gcaccagaca ggacatgctg agacggttca ggttgtgtat
    11041 gatgctaatc ggattagctt aaaggagctt cttttacact actttagaat cattgaccca
    11101 acaagcctca ataagcaggg caatgatcgt ggcagtcagt accgtacagg catttattat
    11161 acggatccat ctgatttgac tactattgat atggtctttc aggaaaaagc ttcggattac
    11221 aaaaagaaaa ttgttgtgga aaaagctccc ctaaagagct ttaccaaggc tgaggaatat
    11281 catcaggatt acctcaagaa aaatcctaat ggctactgcc atattaatgt caacgaggct
    11341 tcatacccag tgattgataa gacaaaatac cctaagccaa gtaaggaaga gattaaaaag
    11401 aagctatcaa aggatgaata tcgtgtgacc caaaacaatg aaactgaaaa agccttttca
    11461 aacaggtact gggattcctt tgaagcaggg atctatgtag atgtggtcac tggtgagccg
    11521 ctgttttctt ccaaggataa atttgaatca ggctgtggct ggccaagctt tagcaggcct
    11581 attagcccag atgtgctacg ctataagaca gacaagagct tcaatatgaa ccgtacagag
    11641 gtgagaagcc gctcaggcaa ttcccattta ggtcatgtct ttaccgatgg tcctaaggat
    11701 cagggtggtc tgcgttattg tattaacagt ttatccattc gatttattcc aaaggctgaa
    11761 atggaagcta aaggctatgg ttacctttta acagcagttg attagaagat tatcctaaga
    11821 tttgttataa taagatgagg aagcacagat ggttgattat agttattaag acctgaagat
    11881 tacttcagtc gatattgcta aatgtgatca ggctcatgcc ctttagtctt gcttaagagg
    11941 tagtagcttt taaaagagtg attacgataa gaggcatttg ctcagagctt gtcctattta
    12001 gctcttgtcg agctatgtgc agagcttgta tgactatggt cactaagcat tagaaatagt
    12061 aggagaaatg gtgtgtactc attacttatt gttgaagacg aataccttgt gcgtcagggt
    12121 attcgttctt tggttgattt tgaccaattt gccatcgatc gtatagcaga ggctgagaat
    12181 ggtcaggtgg cttgggagtt gttccaagaa aatccttatg acattgtttt aacagatatt
    12241 aatatgccaa agcttaacgg cattcaactg gcagagctta taaaggcaag ggctccaaag
    12301 actcatcttg tttttttgac aggttatgat gatttcaatt atgccctatc tgccttaaag
    12361 ctaggggctg atgactacct gctaaagcca ttttccaaat cagatgttga agaaatgctc
    12421 aaaaagctaa agcagaaatt agaaaagctc aaaaaaacag aggcccttca aaaactagtt
    12481 gataagccgc agcaagaagg ctcagaaatt aagctagcta tccaagagcg tttagctgat
    12541 tcaagcctaa cgctaaagag cctatcaagc cagttaggct ttagccctaa ctatctaagt
    12601 gttttaatca aaaaggatct aggtttgcct tttcaggatt acttgattca ggagcgtctt
    12661 aaaaaggcta agctcttatt attaacaacg gatttgaagg tttatgagat agcagagcag
    12721 gttggctttg aggatattaa ttatttttcc cagcgcttta agcagttggt tggaatgaca
    12781 ccaaggcaat ataaaaaagg agaaggccaa tgaagcgcta ccctctttta gtacaattag
    12841 tgagttattt ttttctgatt gtgatttcac taatcactat tctgggagtg atttattatc
    12901 agaccagctc tcataatatc aggcagctca ttgaacgcga aaccagacag agcattcggc
    12961 agagctctca atttattgat gcctacatta agccattaaa ggagacaacc tcagccttag
    13021 ctagccatgc tgagattcag agctttgcta aggcagctaa cagtagtcat caagagcagg
    13081 tgttggcact gatgacaact gtgctgtcga ccaattcaga cctgcgctca gcggttctgg
    13141 tgacaaagga tggtcgtatg gtcacaacca acccaaagct aatcatgact acctcgcatg
    13201 atatgatggc agagccctgg tacaagtcag ctattgaccg caaggccatg ccggtgttga
    13261 cccctgcaag gcagctgtcc tcgcattcta aaaaggattg ggtggtttca gttactcagg
    13321 aggtagttga tgagacaggg aacaatttag gggtgctgcg attggatatt ggctacaata
    13381 ccatcaaatc ctccctagat caattgcagc ttgggcgtag gggctttgcc tttatcgtca
    13441 atgataagca tgaatttgtc tatcacccta aaaataccgt ctatagctca gagcgagaaa
    13501 tggccgcaat gaagccttac cttgctgttg ctgatggcta tacaaagcct aaggattatt
    13561 ttgtttacca aagggtgatt ccagacagtc aatggacctt gattggagtt gcctctttgg
    13621 atcagctgta tcatgtgcag cggcagattt tttggtcctt tttagggacg ggtctgcttg
    13681 caactgtcat ctgtggtctt gggacagtat ttgttctgag aagctggatt ggtcctatca
    13741 ggaggcttca ggctctcatt ttagctattc aaaagggtaa ccgtcagctg cgtgctgagg
    13801 aaattggctc gcctgagtta gctgatttgg cacgtcagtt taacgccatg ctggatcaaa
    13861 ttgatagttt gatgatttca gttgctgaca aggaaaaggc tattgggcag tatcgtctgc
    13921 aagccttagc cagtcaaatt aatcctcatt ttttgtacaa caccttagat actattattt
    13981 ggatggcaga gtttaatgac agccagcgtg tagttgatgt caccaagtct ctggctaagt
    14041 atttccgctt ggccttaaat cagggaaatg aattgattag ccttgctgat gaattggatc
    14101 acgctcgtca gtatttgttt atccaaaagc agcgctatgg tgacaagctg cactatgaga
    14161 tcaaaggtct tgagaaatac caggacttta tgattcctaa gctgattctt cagcccttgg
    14221 ttgaaaacgc tatttatcat ggtattaagg aggttgatag acctggaatg atcagagtaa
    14281 ctgtattaga agctgatcgt catgtgatat tatccgtttg ggataatgga aagggcataa
    14341 gcttagctga tgacagcagt caggccctgc ttgagtgtgg cggtgttggt ttaaaaaatg
    14401 ttgaccagcg cttgaaatta cagtatggtc atctctatag aatggcaatc actagcgagc
    14461 aggctgtttt tactgagatt aagctttatc ttcccaagcc gcttgatggc ctaaatgagc
    14521 tcccctaatc aatctgccct tagtagaaca aggaaaagag aggtttatgt ctttagaatc
    14581 cgattatttt aagcgaaaaa gtcctgtatt tgaggccctt atcccttatg gctttaccca
    14641 agagggtgac acttattgtt atcaggagtc atttatggag ggagatttca aggccttgat
    14701 tacgatcaag tcgtctggtc agctctcagc tagagtgatt gatactgacc ttggggagga
    14761 ctatctcccc ttgagaaatg atagacagca gggagtttat gttggtcagg ttcgtcaagc
    14821 ttatctagag cttcttggac gtttatcagc tgcctgcttt aggtctaccc cttttcagac
    14881 aaggcaggcc aaccaagtgg caacaagcat tagccagcag tggaatgatc cactagatta
    14941 cccctttgaa aaattcccta atattgccac ttatcgtgtt tctggcaagt ggtatgcgat
    15001 ggtattgccc ctgctagccg ataaattagg acaggtgcca aaggtcttac aggggcaaat
    15061 ggttgaggta ttgactgtta gaattgctcc taatcagcta acacacctct tgcagcaacg
    15121 tggtgtttac ccagcctatc atatgtctaa aaagacctgg attagcctat tactagatgg
    15181 tacactagca gatgatcagc tctgggagct agtcacgaaa agtcgtcaat tggctaatcc
    15241 taatggccta gctaacccag atggaccaga ttactgggtg attcctgcta atctcagcta
    15301 ttacgatatt gacgcggaat ttgcagctaa tcctgacatt ctctggacgc aaaaggcttc
    15361 cataaaagct ggagactatg tttttattta tatcactgca ccgaccagat caattcgcta
    15421 tgcctgtcag gtcttgagat cagacattcc taatcaaggc tatcggaaaa atgcgaagat
    15481 taagacctta atgtcgctac gcttgttgca ttgctacgaa gatggtttga tttcccttga
    15541 tttgatgaaa cagtatgggg ttaatgctgt tcgcggtcca agacggttaa gcccacaatt
    15601 agttgcattt ttgaaggaaa aagagtattt taaagatgtg aaacaaaaag aatgataagg
    15661 agagcgggta tgactcaatt tatagcagat cagagctttt gggaattatt tcctgatgct
    15721 aagctaggtg ttttgttgct caggaactat gacaatcagg aagactcccc acaagaggtc
    15781 aagcaattat tggcagacag ccatgacata gctaagcagt atttgactga agagtcgttt
    15841 agtgacaatg agatcattca ggtctatcgt caagcctatc agcgttttaa gacaaaaaag
    15901 ggagccagat ccagtattga ggccctccta aagagggtgg caaatggtca agtcctatcc
    15961 tccattaacc ctctggtgga tatttacaat acagccagtc taaggtttgg tctgccagtt
    16021 ggcgcagaag atagtgattg ctttgtaggt gacttacgcc tgacgttaac agagggaggc
    16081 gatgagtttt acctcattgg tgattctaaa aacagtccaa ctctgccaaa tgagctctgc
    16141 tacaaggacg atgctggtgc tgtttgccgc tgcctaaact ggcgcgatgg tgaaaggaca
    16201 atgattaccg atcgcactaa aaatgccttt ttagtcattg aagcattaga tagcaagacc
    16261 caagcaagac tacaggacgc ccttaagttt atcgaagaca aggctaagtg ctacctgaag
    16321 gcagaaacag cactatatac gctggatcaa gcctcaccaa gtatcacgtt ttaatcaaaa
    16381 aaagctagga agccagtatt cctagttttt tcagttgttc aggtgctttt atttggtgtt
    16441 gtcgagggag atttccttat agctgcaaga tatgacatga cagggaaaca gtttttgctt
    16501 gtttgatcta atcaagcgat taataaaagc ttttaagctg ttggttatgc taaagggctt
    16561 tcttaatcct atcagagaac tttaaaaaat agtataatgt agttaactta tgatgatagc
    16621 taaggaggtc agcatggagt tatttgacaa ggttgatgat acgttaaagg ctttagcgat
    16681 tgactaccag ctggttgagc atgagccagc tttaaccaca gagcaggcag accagttcat
    16741 agagggcatt gaaggggtta gaaccaagac aatgttttta acgaccagga aaaagaacca
    16801 tttttatctg atcattatgg atgatactaa gagactggat atgaatcgct tcaaggagct
    16861 tgttggagaa aagcagatta aaatggcatc agcagaatgc ttgcttgcca agatgcagct
    16921 gccaccagga gttgtttctc cttttggtct tttaaacaac gaggataagg atattcaggt
    16981 ttacgttgat aaagctattg ctcacgaagc tagaatgagc tttcacccaa ataccaatga
    17041 caaaaccatc tttattcaaa cagatgacct ctttaagttt ctagcggcta taggttacgc
    17101 ggtcaatatc gtggatctat agctaaattc aaggttcttc tagcggttct tgctcacatc
    17161 agttcacaaa gctggtggcc tagccaatcc agggcaaaca aaaagcacaa tagcctttct
    17221 tgactactga gaatagccag tagacccttg tgtcatatgc ttatctggta tttgagctta
    17281 aatctcaagg cttttaagta gaggatcaaa caaagaaaac gaccagcaga ccttgcgtga
    17341 tgactgatta tcaagtctgg taggagctaa aatcagtcat ggtcttgagg cctaaaacgt
    17401 cccatttgtc gctcctgttg ctagggcatt agttgacatg tatacccacg actaaccaag
    17461 ccgaggagag ctgtcgctcc cttctcagga gcgtggattg aaatgcaaaa gggatctgat
    17521 agacatttct gcttttaaag ctagtccatc aaaaaaacgc atgacaccac tgtagtggga
    17581 catcatgcgt ttttgctaag ctaaagtgat ttgacgcttc ctttgaaagg gttatttatt
    17641 gctgaagaaa aagggtggtg tgtaatggct caggatttca aagcaagctt tggcctgctc
    17701 attgtcctca cagataatca gacaggtatc atcaccacag atagtggcta cgatttctga
    17761 gatttgcata gcatcaagga tagagccaaa ggattgtgcc agccctggta aggtttttaa
    17821 aataatctga tgctgaacaa ccctgagcat gacaagggcg tcctccatat aaaagcgcaa
    17881 acgatgctcc caacgcgtct gagaaatggc cagcgcttca taatgcgtgt cattaccagt
    17941 tgtaaccttg acaaggttaa gctctttcat atcacgtgat aaggttgcct gtgtgatgct
    18001 tatcccattt tttcgtaagc gttcctgtaa ttcctgctgt gtgtgaatag ttgtttcaga
    18061 aattagagat cgaattaatt gatgacgtgt ttctttttta ttcatttctt ataatattcc
    18121 cctaatgatt agtaacattc agagtataac aaaaagatgg cagtgtgtaa agttttagat
    18181 gaaccgctta caaaaatagc ctttttatgt taaaataaaa cgggtgctta gaaaaggaga
    18241 tttgcgtgat tcgaagagaa gattatcaat accttagaaa acttgatgat ttctgtcatt
    18301 tttcaattga acaatttgac aagattgtcg gccaaatgga atttagacaa gctaaaaagg
    18361 atcatatgtt attttttgaa ggtgataaga gggacagact ctttttagtg acctcaggtt
    18421 attttaagat tgagcagtca gatcggacag gaacctttac ctatactgat ttcatacgac
    18481 atgggacaat ttttccctac ggggggctgt ttacagatga ctactatcat ttttcggtgg
    18541 ttgcgatgac agatgtcacc tacttttatt tcccgactga tttgtttgag gactattcct
    18601 tgcacaatca gcagcagatg aagcatctct acagtaaaat gtcgtccttg ctggagcttc
    18661 atgagctcaa ggtgcgcaat ctcatcacct ccagtgcaag ctcacgtgtg attcaatcct
    18721 tggctatttt actggttgaa atgggaaagg atagcgatac tctgcctttt cagctgacga
    18781 ctactgacat tgcacaaatg agtggaacaa ccagagaaac cgttagtcat gtctttagag
    18841 atttgaaaaa ggaaggcttg attgcagtca aggggaaata cctcacctac ctagataaaa
    18901 actattttct gcagtacaca acctaagatc aagtcaaaag gcttcgctta aaaagttttt
    18961 tgactttttt caatttataa atataagatt tttcgttaaa atgtaaaaaa caaacaagaa
    19021 aacgtataca aaaacataaa cattcatttt caggcgaaaa agtgtaatcg tttacacaga
    19081 ttggctgtga gaaataccct atttttgaat gctgcttgga gtaaactagg ggtgtaagca
    19141 aaagctaaga gtcttagcag tgaattcaca aaacattaga aagaggtaat tcttatgact
    19201 gctcaaacac cgattcatgt ttactctgaa attggcaagc tgaaaaaggt tttgctccat
    19261 aggcctggca aggaaattga aaacctgatg ccagactact tggaacgtct attatttgac
    19321 gatattccat ttttggagga cgctcaaaaa gagcatgatg cttttgcaca agcattacga
    19381 gatgaaggcg tagaggtgct ataccttgaa acactagctg ctgaatcact tgtaacacca
    19441 gaaattcgtg aagccttcat tgatgaatac ctaagcgaag ctaatattcg tggaagggca
    19501 actaaaaaag ctattcgtga gctactgatg tctattgaag acaatcagga attgattgaa
    19561 aaaacaatgg caggtgtgca aaaatcagaa ttgcctgaga ttccagcagc agaaaaaggc
    19621 ttgactgact tggttgaatc aagctatcct tttgcgattg acccaatgcc aaacctttat
    19681 ttcacacgtg atccgtttgc aactattggt acaggtgttt cgcttaacca catgttctca
    19741 gaaacacgca atcgtgaaac aatctatggt aagtacattt tcacacatca cccaatctac
    19801 ggtggcggca aggtacctat ggtttatgac cgtaacgaaa ccactcgtat cgagggtgga
    19861 gatgagctgg ttctttcaaa agatgtgctt gcagtaggta tctcacagcg gacagacgca
    19921 gcatcaattg aaaagctctt ggttaacatc tttaaacaaa atcttggctt caagaaggtt
    19981 ttggcctttg aatttgctaa caatcgtaaa ttcatgcacc tagataccgt ctttacaatg
    20041 gtggattatg ataagttcac gattcaccca gaaatcgaag gagatcttcg cgtttactca
    20101 gtgacctatg aaaatgaaga gcttcgtatt gtagaagaaa ctggtgattt ggctgagctt
    20161 ttagctgcta atctgggagt tgagcgtgtt gagcttattc gctgtggtgg tgataacctt
    20221 gtggcagctg gtcgtgagca atggaacgac ggctcaaaca cgctaacaat cgcaccaggt
    20281 gtcgtggttg tttataaccg taacactatt acgaatgcca ttcttgaatc aaagggcttg
    20341 aagctcatta agattcatgg aagtgaattg gttcgcggtc gtggtggacc tcgttgcatg
    20401 tcaatgccgt ttgaacgtga agacatctag gagaggcaaa tgacaagggt tattgttgga
    20461 aatcagcctt ttcaacgggc agctagctta tatattcgct atcaggtttt tgtcttagaa
    20521 cggcagattg atcggcaaga tgaatttgat tgcttcgacg ataacgatcg cgtgtatgca
    20581 gtcttgtatg atggtgatca gcctgtatcc acagctcgct ttttacccac agctaaagat
    20641 caggctcgtc taacaagagt tgctacgctg cgtcagtatc gtggtagggg ctatggtgcg
    20701 caggtgatag aagcgcttga gcagtatgcc agagagcaag cttacgagcg attggttatt
    20761 catagcgaga ttagcgcaca gtcattttat gaaggtcttg gctatcaagc ctttggcgag
    20821 ccttatgatg aagacggtga gccttgtcaa tcagtagaaa aatatttata aaaaggagaa
    20881 tttaaatgac acaagtattt caaggacgta gcttcttagc agaaaaagac tttacacgtg
    20941 aggaatttga atacctcatt gattttgcag cacacttgaa agaccttaaa aagcgtggta
    21001 ttccacatca ctatttagaa ggtaaaaata ttgccctctt gtttgaaaaa acatcaacgc
    21061 gcacacgtgc tgcctttaca actgcggcga ttgatttagg agctcatcct gaataccttg
    21121 gcgctaacga tattcagctt ggtaaaaagg aatcaacaga ggacacagct aaggtattgg
    21181 gtcgtatgtt tgatgggatt gaattccgtg gctttagcca acgtatggtt gaagaattgg
    21241 cagaattctc aggtgttcca gtgtggaatg gcttgactga tgaatggcac ccaacccaaa
    21301 tgcttgcgga ctaccttact gtcaaggaaa actttggtaa gcttgaaggc ttgaccttgg
    21361 tttactgtgg tgatggacgc aacaacgttg ctaattcact gttagtagca ggtaccttac
    21421 taggtgtgaa tgttcatatc ttctcaccaa aagagctctt cccagcagaa gacatcgtga
    21481 agctggctga gggctatgct aaagcatcag gtgcgcatgt gttagttact gacaatgctg
    21541 atgaggctgt aaagggcgca gatgtgcttt acactgatgt gtgggtgtca atgggtgaag
    21601 aagacaagtt tgaagagcgt gtgaagctct tgaagccata tcaagtgaac atggagcttg
    21661 ttaaaaaagc cgccaacgac aaccttatct tcttacattg cttgccagcc ttccatgaca
    21721 caaatactgt ttacggaaaa gacgttgctg agaaatttgg tgtagaagaa atggaagtaa
    21781 cagatgaggt cttccgcagc aaatacgctc gtcactttga ccaagcagaa aaccgtatgc
    21841 acactattaa agcggttatg gccgcaactc ttggtaatct tttcattcca aaagtgtaag
    21901 ctgtgattgg taccttttaa tttattttag ctcatttcat taatttaaca tttaactact
    21961 aaaaaacgta ctttaactac atgacgagtc gttctggttc tcgtgtcctt gaccggaact
    22021 gggacggctt atttttatga aaaggtaaga ggtaatcact atgacagaag aaaaaaaacg
    22081 aggttttaaa attccttctt cttacactgt tttgtttatc atcattgcta ttatggcagt
    22141 attaacctgg tttattccag ctggtgctta tgagactgct aaggatggcg gtgtgatttc
    22201 agggacctac caaacggtta agtcaaaccc tcagggcttt tttgacattt taatggcacc
    22261 tgttcgaggc atgctaggtg tcaaagggac tgaaggggca attcaggttt ctttctttat
    22321 tttgatggtt ggtggctttt taagggttgt caacaagaca ggtgcgcttg atacagggat
    22381 tgcttctgtt gtgcgtaaaa ataagggtag agaaaagctg cttattgcga ttttgattcc
    22441 tttgtttgca cttggtggca caacctacgg aatgggagaa gaaacaatgg cgttttaccc
    22501 tcttcttatt ccggtaatga ttgcggttgg ctttgatagc attgttgcag tagctattat
    22561 cctgattggt tcacagattg gctgtttggc ctcaaccatc aatccctttg ctactggagt
    22621 ggcagcagat gcagccggtg ttagtatcgc agatggtatg atttggcgga ttatccaatg
    22681 ggttgtcctt gttggtatgt ctatctggtt tgtttacagt tacgctagca agattgaaaa
    22741 agacccaagc aagtccttgg ttgctgacaa agctgaagaa cataaggaat tcttccagct
    22801 gcaaaattcc ggtgaggatt tgactagtcg tcaacgaaag gttttagcca tttttacctt
    22861 gacatttgtc atcatgattc ttagcttgat tccttgggaa gattttgaca ttcaattatt
    22921 tacaaatatc aacacttggc taacaacaac acctgtttta ggtggtatta ttggtaaaac
    22981 aatgggagcc tttggtactt ggtatttccc agaaattacc atgctcttta tcatgatggg
    23041 tgttttagtg gctgttgttt atcgcatgag tgaagatgac ttcttctcag cctttctaag
    23101 tggtgcaggt gagttcctcg gtgttgcgat tatttgtgcg gtagcgcgtg gtatccaagt
    23161 gatcatgaat ggtggtatga ttacagcaac cattcttcat tggggtgaaa caggtcttgc
    23221 aggcttgtca tcacaggtct ttgttgtctt ggcctatatt ttctatttgc caatgtcctt
    23281 cttgattcca tcaacatcag gacttgccgg tgcaacaatg ggaatcatgg ctccgcttgg
    23341 acaattctca aatgttcctg ctcatttggt tatcacagcc ttccaatcag catcaggtat
    23401 cttaaacatg atttcaccaa cctctgctat tgttatggga gcgctcgcac ttggacgtat
    23461 tgatctaggt acttggtgga aatttatcgg caagtttatc gttatggtaa tgcttgttag
    23521 tgttttgttg ttagtagtag cgacattctt ttaagagata ggaggctcct atggaaacct
    23581 atatccaacc aagacaccaa gaggcttgtg tagccgcgat taaaaaaata gtatcttacc
    23641 cttctgtgct aaatgagggg gaaaatgaca caccctttgg ccaagccatt caagatgttc
    23701 ttgaagcaac cttagccctg tgccaagatc ttggttttaa tacctatatt gatcctaaag
    23761 gctattatgg ctatgctgaa ttgggcgatc aaacagaggt gcttgctatc ctttgtcact
    23821 tagatgtggt gcctgctggt gatttgaagc tgtggcataa agatcccttt acttgtattg
    23881 aaaaagatgg ctgcttgtat ggacgtggca ctcaagatga caaggggcca tcgatgatgg
    23941 cactctttgc cactaaagca cttatggacg ctggtgtggt ctttaacaaa cgcattcgct
    24001 ttatctttgg aacagacgaa gaaaccctct ggcgctgtat gaaccgttat aatgaagtag
    24061 aggaggaggc aacctttggt tttgccccag actcaagctt cccattgacc tatgctgaaa
    24121 aggggctttt acaagctaag ctagttggta agggatcgcc taaactcaat cttgaggtgg
    24181 gtcaggccta taatgtcgtt ccagctagag cctcttatca gggagacaag ttggaggcat
    24241 taaaggaaga gcttgacagg cttggctttg aatatgttgt caaagatgac gagctaaccg
    24301 tctatggact tgctcagcat gccaaggacg ctccagatgg gattaatgcc cttatcaggc
    24361 ttgcaaaggc tcttgtagtg cttgagccag agccagtcct tgactttctt gctcatgtgg
    24421 ttgatgaaga cggcagagca gtcaatattt ttggtccagt tcaggacgag ccatcaggag
    24481 ggcttagctt caacgtagct ggtcttacct taacaaaaga gatgacagag attcgtttgg
    24541 acattcggat tccggtctta gcagataaag ataccttagt agaccagtta agccaaaaag
    24601 cgcaggacta cggtctagct tacgaggaat ttgattattt ggcaccctta tatgtgccct
    24661 tggacagcga gctagtaact accctgttag aggtatatcg taaaaaaaca ggggaccaat
    24721 cgccagccca atcatcaggt ggagcaacct ttgctcgtac aatggctaat tgtgtggcct
    24781 ttggagcatt atttcctgat gctgttcaaa cagaacacca agaaaatgaa catatcgtct
    24841 tagcagatgc ctatcgtgca atggatattt acgcggaagc catctaccga ctaacacgat
    24901 aagatgagga gtatcatata tgacaaaaca aaaaattgtt gtcgcacttg gaggaaatgc
    24961 aatcctctca acagacgcgt cagctaaggc acaacaagag gccttggttt cgacatcaaa
    25021 atcactagtg aagttaatca aagaaggcca tgaggtgatt atcacgcatg gcaatggtcc
    25081 gcaggttggt aatctcttat tgcagcaggc agcagctgat tctgagaaaa atccagccat
    25141 gccattagat acctgcgttg ccatgacaga aggcagcatt ggcttttggt tagtcaacgc
    25201 cctagacaat gagctgcaag cccaaggcat cacaaaggaa gtggcagcag ttgtcaccca
    25261 ggtcattgtt gatgaaaatg accctgcctt taaaaatccg actaaaccaa ttggtccttt
    25321 cttaaccgaa gaagacgcta aaaagcaaat ggcagaatca ggtgctagct ttaaggagga
    25381 cgctggtcgt ggctggcgta aggtggtgcc atcaccaaag ccaattggta tcaaagaagc
    25441 taatgtgatt agaagcttag ttgattctgg tgttgtggtg gtcagtgctg gtggtggcgg
    25501 tgtgccagtt gttaaagacc ctgcaagtaa aacgcttacc ggtgtggaag ctgttattga
    25561 taaagacttt gctagccaaa ccctttcaga attggttgac gctgatctct ttattgtctt
    25621 gacaggtgtt gataatgtct atgttaactt taacaagcct gatcaaagaa aattggaaga
    25681 ggtaacggtt tctcaaatga aggaatacat cgctcaggac caatttgctc ccggaagcat
    25741 gctgcctaag gtggaggctg caattgcttt tgtggaaaac aaatcaaatg ccaaagctat
    25801 catcacatcg ttagaaaata ttgacaatgt tctctcagca aatgctggta cacaaattat
    25861 cgcaggctaa ttcagatgac tgcacaatga gcttaggctt ttgtgctttg ataggtttta
    25921 gctgataagc ttgaaaaatt gatttaaaag gttaaattag gttaatttag ccttttcttt
    25981 tacttttaat cggtgtataa taagcgtaat atttttttat ttttactcat gattagaatg
    26041 gtaaaaaata aaggtgactt agtcgcgaaa atgatttaaa ggaggagcta tgaaaaaaag
    26101 ctttattcat caacaagagg aaatttcctt tgttaaaaat acatttacgc agtatttgat
    26161 tgctaagctt gatgttgttg aggtgcaagg tcctatttta agtagggtcg gagacggcat
    26221 gcaggacaat ttatctgggg ttgaaaatcc ggtatctgtc catgtcttga acattcctaa
    26281 tgcaaccttt gaggtggtgc attcgctagc aaaatggaag cgtcatacct tagcacgttt
    26341 tggctttaat gaaggtgaag gtcttgtggt gaatatgaaa gcgctccgtc ctgatgaaga
    26401 ttcgctagac cagacgcatt cagtgtatgt ggaccagtgg gattgggaga aggttatccc
    26461 tgatggtcag cgcaatctag cttacctcaa agaaactgtc gaaacgattt acaaggttat
    26521 ccgcttgaca gagctagctg ttgaggcacg ctatgatatt gaagctgtct tgccaaagaa
    26581 aattaccttc attcacaccg aggagcttgt tgccagatac cctgatttga caccaaagga
    26641 gcgtgaaaat gctatcacaa aagaatttga tgcggtattt ttgattggta ttggcggtgt
    26701 attgccagat ggcaagccac atgacggtcg tgcgccagac tatgatgact ggaccagtga
    26761 gtcagaaaat ggctaccatg gcttaaatgg tgatattctc gtttggaatg agcagctagg
    26821 cacagccttt gagctattct caatgggaat tcgtgttgat gaagaggctc taaagcgtca
    26881 ggtggacatt actggagatc aggaacgcct acaatttgat tggcacaaat cgctgctaaa
    26941 tggtctgttc cccctaacca tcggtggagg aattggtcaa tcgcgtatgg ccatgttttt
    27001 gcttcgtaaa aagcacattg gagaggtcca aacatcggtg tggccacaag aggttcgcga
    27061 tacctacgac aatattttat agatgatacg gaggctaggt ttttacctat agcctctatt
    27121 tttgtcccta agtgatgctt cattagagct catttagtgc taagcaggct cgtcagttat
    27181 ataataggtc aaaaatttga aaaaatgaat catttttaag gcttgacact agatttttgt
    27241 tataatatca gttatgagaa ttgtatcagg tgaatttgga gggcgtcccc taaaaacgct
    27301 cgaaggcaag actactcgac ccacatcaga taaggtacgt ggcgcgattt ttaatatgat
    27361 tggtccttat tttaagggcg gacgtgtctt agacttgttt gctggatcag gtggcctatc
    27421 aatagaggct atttctaggg gcatgtcaga ggcagtgctg gttgagcgtg atcgtaaggc
    27481 gcaagccatt atccaagcca atattaagat gacaaaagct agccagcaat ttacgctatt
    27541 aaaaatgaac gctgagcgtg cacttgatca cttatccggt cagtttgatg tggtgttttt
    27601 ggacccacct tatgctaagg aaacgatagt agccaatata gaggccttgg tggagaaaaa
    27661 tcttttaagc gacgatgtga tgattgtttg tgagacggat cggtcggtag ctctgccaga
    27721 ggcaattgcc tggctaggga tctggaaaga aaaacaatat ggaattagca aggtaacagt
    27781 atatgtcagg taagattgga ctttatacag ggtcatttga cccagtgaca aatggacaca
    27841 tggatatgat taagcgtgct agccatttgt ttgagcatgt ttatgtcggg atttttaaca
    27901 atccaaataa gcagagcttt tttacttttg agctgcgagc tcaaatgcta agcgaagcgg
    27961 tttgtgcctt gccaaatgtg acagtggttt ctgccgagca tggtcttgca gttgacctgg
    28021 ctagggagct gtctgtgacc caccttatcc gagggcttcg caatacagct gattttgact
    28081 atgagatagg cttagagtat tttaatcata gactagcccc tgatattgag accatttacc
    28141 tgatggcgac tcatgacctg cagcccgtta gctccagtcg tatcagagag ttgattgcat
    28201 ttagagcgcc aattactggt ttggttccgc aggctgttat taatcaagtg gagaaaatga
    28261 atgaaaacaa taaaaaaaat taaatggtgg ctgattggct ttgttgcctt gctttttcta
    28321 ctgttgacac tgtttttccc cttgccttat tatattgaaa tgccaggtgg agcctatgat
    28381 attcgctcgg tattgactgt caatggcaaa gaggataagg aaaagggagc ttatcagttt
    28441 gttgtagtga gcctcagtcg ggccaccttg gctaaattgc tctatgcttg gctaacgcct
    28501 ttcactgaga ttagcaccat ggaagatact actggtggct atagcgatgc tgactacctg
    28561 cgaattaatc gcttttatat ggaaacctct caaaacagcg ctgtttatca ggcccttact
    28621 ctagcaggca aggaggtaag ctttgattat aagggtgttt atgtcttaga cgtcagcaag
    28681 gattctagct ttaaaggtgt gctgcaccta gcagatacag tgacaggtgt caatggtaaa
    28741 acatttacaa cgtctgccga tctgattgat tatgtttctc atttgacctt gggagatgag
    28801 gtgcaggtac aatttacaac cgctggtgag tcaaagactg aaaaaggaaa gattattaag
    28861 cttaaaaacg gtaaaaatgg gattggcatt accctgacag accacacaca ggtcatttct
    28921 ggtgatgagg tcgactttag cactggaggt gtgggtggac caagtgcagg cttgatgttt
    28981 actcttgata tttatgatca aatcaatcac gaagacttgc gcaagggacg tgtgattgct
    29041 ggtacaggaa ccattggcaa ggatggaaaa gttggagata ttggcggggc gggcctaaag
    29101 gtggctgccg ccgccgctgc tggtgctgat attttctttg ttccaaataa tcctgtgcat
    29161 aaggacgtca aaaaagcaaa tcctaaggct attagcaatt acgaggaggc taaaaaagca
    29221 gctaaacgac taaagacagc aatgaaaatt attcctgtga aaaccgttca agatgctata
    29281 agctacctta aaaaatagaa gcaatgcgaa gcaggctaat agggcatgct ctgtcttgct
    29341 tctagttggt ggaatttagc tagctcaaag gtcttgagac ctaagcataa ggtctagaca
    29401 gtattctaga gctagacctt atgcttgatc ctgaacaagg aagaccgcca aagaagaaca
    29461 aaatcctcag gccaaaagag cccgtaggga aatattgcca ttatctatca aggctttttg
    29521 aagaaaatca cttaaagaca gtagggcgtt aggctttact gtcttagttt ttcttgcctg
    29581 aagtcatggc tgctgatgat gttacatcaa ggcttactag ccagcagagc acaaggagca
    29641 gctttggctt aggtttattt tctctgctga ctagtaaaga aggttgctgt cagtctgctt
    29701 acaaaaacct aaaaatagtg tataataggt aggctatggg ctgtcaggag tcgctagcct
    29761 gcttacccag accagccctt tgagaagagc aagcatggct cttctcagaa taacccagga
    29821 ttaacagaca tcaaaattaa tgctaaggaa aggagctata tgaaaagaga tattttacca
    29881 gagatgtata attacaataa atttcccggt ccggaattta ttcattttga tcattatgtc
    29941 aaggctgaag gcattgagtt attgctgctg aaaaatgaaa aaaatgcttt taacacaacg
    30001 agctttggtc agcgcttcac agagatatta ttaaagtatg actatattgt tggagattgg
    30061 ggcaatgaac agctgcgtct caagggcttt tacaaggatc atcatgatgt caaaaaagct
    30121 agtcgtattt ctcgcctaga agactatatt aaagaatttt gtaactttgg ctgtgcctat
    30181 tttgttttgg aaaaccctaa tcccaaggac atgccaaaag aggaggaaag gccatcaagg
    30241 cgcaggaaat cgtctaaagc caatcgccgc agaaatcagc ctcagcatag tcagcaggca
    30301 cctgctaaag acaacttcaa aaagctaacc aaggataggt cagcggacaa gccaagcttt
    30361 accagcaaaa agcgcccagc tcctaataag accaagggaa accaaaggcg ctctcgtact
    30421 agtcaactga accataaaac ggatcacttt atcatcagaa agaaggacaa ttaatctatg
    30481 aaaccatcaa tctatggcct aacgcgcgac gagctaattg cttgggcgat tgacaatggt
    30541 caaaaggcat tcagagcgac acagatttgg gactggcttt acagaaaacg ggttcaatcc
    30601 tttgatgaaa tgactaacat ttctaaggaa tttgttgcca ttctaaagga cagcttttgt
    30661 attaatccct tgaagcagcg tgttgctcag gaatcagctg atggaacggt taagtatttg
    30721 tttgaattgc cagatggtat gctgattgaa acggttttga tgcgtcagca ctatgggcag
    30781 tcggtctgtg taactacgca ggttggctgt aatataggct gcaccttctg cgctagtggc
    30841 ttgattaaaa agcaacggga tttaaacagt ggtgaaatca ctgcacaaat tatgatggtg
    30901 caaaactatt ttgataagcg tgctcaagac gaacgtgtca gccatgttgt tgtgatgggg
    30961 attggagagc cctttgataa ttatcaaaat gtgatgacct ttcttcggac gatcaatgat
    31021 gatcatgggc ttgctattgg tgctcgtcac attactgttt caacctcagg cttggctcac
    31081 aagattcgtg aatttgccaa tgaaggagtc caagttaatc tggctgtgtc actgcatgca
    31141 cctaataatg agctgcgctc aagtatcatg aggatcaatc gttccttccc acttgataag
    31201 ctcttttcag caatcgaata ttacattgaa acaactaatc gtcgtgtgac ctttgagtat
    31261 atcatgctta ataaggttaa tgatggggta gagcaggcac aggaattggc agatttgacc
    31321 aaaaggattc gcaagctgtc ttatgttaac ctgattccct ataatcctgt ctcagagcat
    31381 gaccaataca gtagaagtcc taaggagcgt gtggcagcct tttatgacat tctaaagaaa
    31441 aatggagtga actgtgtcgt tcgtcaggag catggtacag atattgatgc tgcctgcggt
    31501 cagctgcgct ctaataccat gaaaaaggac cgacaaaaag cagcagctgc aaggacatga
    31561 tgacttggtc aaggttgctg atttgattga taggagatgg agataaaaat ctgacctcaa
    31621 ataaagcaaa caaataggtc tagttttctg agatcccgaa agcaggtctt gttcgttttt
    31681 taatgaatga gactaggtca taaagtacat gcgttaagaa tgtctaaagt gcagctcttt
    31741 ttgtcccagc ctccctcttt tatcttggta gcagttgtca agtaattgct aagcaacagt
    31801 gttttatctt tattggctgt aaaaaaagat atagtgcctt tattcacacc ttttctgaat
    31861 cacttgagcc ttgttctgac cgctcctttt ggtgcttctg atccatatag cctaagcttt
    31921 tcagagctat gaatcgaggc aaaataatag gtgttagccc tagctgcttg atgtagctag
    31981 ggcttttgtg acctagctgc cagtgagcct ttcaaatagc aatatggcta taaggcccag
    32041 tgtcagatag ggaataaaag ggattttctt agtttgtaga agtaggcagg ctagaattcc
    32101 gatcagactg gcaatttgga cgatccataa caaagagcta agcttgacca caagagcaag
    32161 attagctagg taaagaaaat ctccggcacc aatattgata ggaaaagcta cgcttagcag
    32221 tgcaagcaaa agcaatagca ctgttaacag gttaatgcta taaaatggca gcagaaacaa
    32281 aaagctcatc agccagatga gcaaaggata ctcttgactg tctaaatcaa aaaagcacag
    32341 tagcaaagag aagcatagga gataaagctg tgtccaggtc aagccgcaaa gggcagccag
    32401 tccgaaaatg aggctggtga ttatttctaa ataaggaagc ataacccagt gcttttgttc
    32461 atgcttagag ttgtaagtgg gctttgccat aggaaaaaag aggcttgaaa gatgaagttg
    32521 acctatatag agcttgaccc aagcctttgc ttgctgttca gaaaacaggt taagtattag
    32581 ccgaaagagg tttcccacaa gaaaaccaca atagcaataa aaaatagtgt tcatacttat
    32641 ttatccgaaa aacaatttaa attcttgcaa tattttaaaa aacggtgtac aatgaaacta
    32701 taaaacgaga atgattctaa ataagctgtt gatacttatc tgaattggct cgttatcgtc
    32761 gaatggagct gacaagagag tgacttttct tgctgcatac cattcatgcc cttttatatc
    32821 tatcagtaag gagagtttat tatgacaaac acactcgttg aaaacattta tgcatcagta
    32881 actcataata tttctaaaaa agaagcatca aaaaatgaaa aaaccaaggc tgttttaaat
    32941 caagcagtag cagatctatc tgtagcagct tcaattgttc atcaggttca ttggtacatg
    33001 cgtggtcctg gctttttata cctgcaccct aagatggatg agctattaga ccgcttgaac
    33061 gcgaacctag atgagatgag tgagcgcttg attactattg gtggggcacc ctactcaacc
    33121 ctagaggagt tttcacagca ttctaagcta gatgaaacaa agggaagcta tgataagtca
    33181 gtagctcagc atttagctcg tttggtagag gtttaccttt accttaccag tctttatcag
    33241 gttggtttag acattactga tgaagagggt gatgctgctt caaatgattt gttcacagca
    33301 gcaaaggctg acgctgaaaa gactatttgg atgctacagg cagagcgtgg tcaaggtcct
    33361 gctattttct aaagcgtcat acaactgata taacataaaa aaggcagagc gtggtatagc
    33421 cctgtctttt taacgccttt aaagtcagct attagtgcta gtgatgtcag gtctcacagc
    33481 ttttttatga tggatgacca acatttttag accttgtcac cacagcagag catgtggcat
    33541 ttagtccacc ttgggctcac gtcgatggtc ttacttatga tatatcaagg cttgtgacat
    33601 taccgttgcc ttttatcttc agtctgagct gctggttcct actgctgatg ctgcttgata
    33661 gtgttatagt gattttcaga aatatggaaa gcgattgcat aattgtcttg aaatctcatg
    33721 cgtaatttgc taaaatctag ttatatgaaa acattatacg atgtacagca gctgttaaaa
    33781 ggctttggta ttgttatcta catgggaaag cggctttatg atattgaaat gatgaaaata
    33841 gagctgcaaa ggctatatga tggtggcttg ttggataaac aggcttattt aactgctgag
    33901 ctgattttac gacgtgagca tcgattagag ctaaaaagag aagggcaaga aaatgagtca
    33961 aaaattgata gggattgatt tgggcggaac cacgattaaa tttggtattt taacctcaga
    34021 gggtgacgtt caggaaaaat gggcgattga gacaaatgtt ttagaggacg gtaaacatat
    34081 cgttccagat attgtcgcct cactcaagca tcgccttgac ctttatggac tgactaagga
    34141 cgattttatc ggtattggta tgggctcacc tggagctgtc aatcgcacag atcatactgt
    34201 tacaggggcc tttaacctca actggagagg cacccaagag gtgggatctg ttattgaaag
    34261 ggagctagga attccctttg ctattgataa tgacgcaaat gttgcggccc tcggcgagcg
    34321 ctgggtcggt gcaggtgaca ataatcctga tgtggtcttt atgaccttag gaacaggtgt
    34381 tggtggtggt atcatcgctg atgggaactt gattcatggt gtggctggag ctggtggtga
    34441 gattgggcac atgatagtag agccgcttaa gggctttgct tgcacctgtg gctcacaggg
    34501 ctgcctggag acagtggcct ctgctacagg tgttgttaag gttgctcgtc ttttagcaga
    34561 agcctacgaa ggagattcaa gcattaaggc agcgattgat aatggagagg ctgtctcaag
    34621 caaggacatt tttgttgcag cggaggctgg tgatgccttt gccaactctg ttgttgaaaa
    34681 ggtcagttat tatctaggac tggcagcggc taatatctca aatattttga accctgattc
    34741 ggtcgttatt ggcggtggtg tatctgctgc gggtgagttt ttacgttcac gtgttgaaaa
    34801 gtactttatg acctttacct ttccgcaggt tagacagtcc actaaaatca aaatagcaga
    34861 gcttggtaat gatgctggta ttattggtgc agctagcctt gcaagacaat ttatcacaga
    34921 ataggagtta atgatgtcac cacttacaat gattggctgg gtattgcttg cgggagtgat
    34981 tgcctattac ctttggaatt atgtttccta tagaagaatg gcaaagcagg ttgataatga
    35041 tacctttaag gagctgatgc gtcaggggca agtgattgac ctgcgcgatc cagcttcctt
    35101 tagggcaagg catatcctag gcgctagaaa ttttcctgcc cagcagttta ctacctctat
    35161 taaggctttg agaaaggaca agccaatctt gctttatgaa aatgtaagac ctcaatatcg
    35221 ggtcaaagca gtcaaaacat tacgtaaggc tggctatacg gacctttatg tcctaaaagc
    35281 gggactagat tattggaatg gtaaggttaa atagccttat agtccttttt gctgagctaa
    35341 cgtttgctgc tatgtgtcgg aacgttgcaa gcagcagctt atctaagctt gtcatgctag
    35401 tttcacagcc caaagtggct ggccgtataa acgcagctgc ttttagatgc cggtaggagc
    35461 ttttgtcagc ttctttaggg attgttttaa gtgatgtaga gaggccgttc tgagagaaag
    35521 ccttgtagtt agaaaaagag atgagaaagc taaggctctt gctgctgttg taagagttag
    35581 ctttcttttt cttttttgtg tggcgcattt aagggcttga aaacatttac aattccctca
    35641 gatcggtttt ttaaaaaaat ttgtgttata ctgttttagt taaaactatt tatgctacaa
    35701 gaggaaaaaa tgacaaaatt tagagaagat attcgtaacg ttgctattat tgcccacgtt
    35761 gaccatggga aaacaacgct cgttgatgaa ttactaaagc aatcccatac actagatgag
    35821 cgcaaagagc ttcaagaacg tgcgatggat tcaaatgacc ttgaaaaaga gcgtggtatt
    35881 accattcttg ctaaaaatac cgcagtagct tataacgatg ttcgtattaa tatcatggat
    35941 actcctgggc acgctgactt tggaggcgag gttgagcgta tcatgaaaat ggttgatggt
    36001 gttgtccttg ttgttgacgc ttacgaggga accatgcctc aaacacgctt tgtgctgaag
    36061 aaggccttag aacaaaattt aaccccaatc gttgtggtta ataagattga taagccatca
    36121 gctcgtccag ctgaggttgt tgatgaggtt cttgagcttt tcattgagct tggtgcagac
    36181 gatgatcagc tggagttccc tgttgtttac gcttcggcga tcaatggcac atcttcgttg
    36241 tcagatgatc ctgctgatca ggaaaaaaca atggctccga tttttgatac cattatcgat
    36301 catattccag cacctgttga taactcagct gagccccttc aattccaggt gtcacttctt
    36361 gattacaatg attttgtagg tcgtattggg atcggtcgtg tctttcgtgg gactgttaag
    36421 gttggagatc aggtgacgct ttcaaagctt gatggcacca ctaaaaattt ccgcgttact
    36481 aagctgtttg gcttcttcgg gcttgagcgc aaggagattc aagaggccaa ggctggtgac
    36541 ttgattgcag tttctggtat ggaggacatt ttcgttggtg agacgattac accaacggat
    36601 tgtgtggagg ctttgcctgt tcttcgcatt gatgagccga cacttcaaat gaccttcttg
    36661 gttaacaact ctccctttgc tggtcgtgaa ggcaaatggg taacctctcg taaggttgag
    36721 gagcgtttgc ttgtggagct tcaaacagat gtgtcccttc gtgttgagcc aacagaatca
    36781 ccagataaat ggattgtgtc aggtcgtggt gagctgcatc tatctatttt aattgagacc
    36841 atgcgtcgtg agggctatga gcttcaggta tcgcgtccag aggttatcat taaggaaatt
    36901 gatggtgtca agtgtgagcc ttttgaacgt gtacagattg acacaccaga ggaatatcaa
    36961 ggtgctatta tccaatcctt gtcagaacgt aagggggata tgcttgatat gcagatggtt
    37021 ggtaatggtc aaacgcgtct tatttttctc attcctgccc gcggcttgat tggttattcg
    37081 actgaatttt tatcaatgac acgtggctat ggtatcatga atcatacctt tgatcagtat
    37141 ctgccagtgg ttgctggtga gattggtgga cgccatcgtg gagcgctggt ttcgattgaa
    37201 aacggtaagg caacaaccta ctcaatcatg cgtattgaag agcgcggaac aatctttgtt
    37261 aacccaggaa ctgaggttta tgagggcatg attgttggtg aaaattctcg tgacaatgac
    37321 cttggggtta atatcacaac tgctaagcag atgaccaacg ttcgttcagc aacaaaggat
    37381 cagacagctg ttatcaaaac accacgtatt ctaacccttg aggaatctct tgaattcttg
    37441 aatgatgacg aatacatgga ggtaacgcca gaatcaatcc gcttgcgcaa gcaaattttg
    37501 aacaaagcag cgcgtgataa agctaataaa aagaaaaaat cagcagaata aaggctggtt
    37561 ggtctgagca tcacactccc ttgccgcttt aactagtaag ctaggttggc agaggattga
    37621 aaggagcttt ctgtgtttta tcttattatt gcagccttga ttacctctta ttacctgttt
    37681 atggcaccaa agagcgtccg taacacacta ggtatgattg gtttggttgg tttggttgcc
    37741 ctattgattg tgctagctgg cttaagtttt atcaaaatca tgcaaacgcc caaggaaatt
    37801 ttcgttggtc tagccatgat agtattgggc tactatgccc taagggacat tcaaaaaatc
    37861 cctaaaaaac caaagagtaa acattagcat caagcattga gtcaaatctt aatagggttt
    37921 gactttttct gtctttgtac tggccttatg cgctgctatc tgtaaaatct tgaaaaagca
    37981 gttaaataag ggtaaaatag tagtcaaata gacatagata gtgtggataa aaatgaagac
    38041 aataacggaa ttccaaaata aaaaggtatt gattcttggc ctggccaaat cgggcgaagc
    38101 agcagctagg cttttagccc ggttgggagc tattgtgaca gttaatgata gcaagccctt
    38161 tgaggaaaat cccgcagcac aggctcttct tgaggagggc ataagggtta tttgtggtag
    38221 ccaccccttg gagctgttag atgaagactt ttattgtatg gttaaaaacc cagggattcg
    38281 ctatgacaac ccgatggtgg tacgcgcctt agataaggct atttctattc taacagaggt
    38341 tgagctggct tatttggtat ctgaagcacc tatcattggt attacgggct caaatggtaa
    38401 aaccactaca accacaatga ttgctgatgt gctaaatgct gggaaccatt cagctctttt
    38461 ggctgggaat atcggctttc ctgcttcaga ggtggctcaa gctgctacag caaaggatat
    38521 actggtcatg gaattgtctt cctttcagct gctggggact gagcagtttc agccacatat
    38581 tgcagtcatt actaacctag tgcctactca tcttgattat catgggagtt ttgaggacta
    38641 tatagcggcc aagtggcgca ttcaacatcg aatgaccgat aaggattacc ttgtgttaaa
    38701 tgctgatcaa gagctggtaa aatcattggc tcaaaagact aaagcaagtc ctgtcttttt
    38761 ttctaccaaa gaaaaagttg atggtgctta tttggcagat gggtatcttt atttcaaaga
    38821 ggagaggctg atgtcagcag ctgagcttgg tgttcctgga aggcataaca ttgaaaatgc
    38881 tcttgccacc attgctgttg caaagctaag aggcatttct aatcaagtga tatcaaggac
    38941 tttgtctcac tttagggggg tgaagcaccg ccttcagtta gttggtacat tgaatcaagt
    39001 gaccttctac aatgacagca agtcaaccaa tatcttggct tgtcaaaaag ccttgtcggg
    39061 ctttgataat agcaaggtta tcctgattgc tggtggcttg gatcgtggca atgaatttga
    39121 tgagctggtg ccagacctcg ttggtcttaa aaagatgatt cttttagggg aatccgcaga
    39181 gcgtatgaag cgagctgcag acaaggcagg agtgtcctat cttgatgcca aagatgttgc
    39241 agctgccact aaaatagcct ttgagcaggc aaaggctggt gatattatct tgctgagccc
    39301 agccaatgct agctgggata tgtatccaag ctttgaaagc cgcggcgacg agtttttagc
    39361 agcctatgac gcgttaaaag gagaggctca atgaccaaga aaatcatttt taccggtggt
    39421 ggaacagctg gtcatgtcac tttaaacctt atcctcatac cgaagtttat caaagatggc
    39481 tgggaggttc actatattgg tgatgacaaa ggcattgagc atcaggagat caaaaagtca
    39541 ggtcttgatg tcacctttca tgctattgca actggaaaat taaggcgtta tttctcttgg
    39601 caaaacctgc ttgatatctt caaggtaggc tttggtgtca tgcaatcact ttttatcata
    39661 gctagactaa ggcctaaggc tctcttttca aagggaggct ttgtgtcggt tcctcctgtg
    39721 attgctgcaa ggcttttagg ggtgccggcc tttattcatg agtcggatct ttctatgggc
    39781 ttggctaata ggattgctta tcggtttgca acaacgatgt atacaacctt tgagcaagag
    39841 cagacactgg caaagctcaa gcatgttgga gcggttacca aggtgacagg tcctgggagt
    39901 cgatcggtga cttctaagca gcttgaagct gttttggagt attttgatcc taatttaaaa
    39961 acacttttgt ttattggagg ctccgcaggg gctagggtgt ttaaccgctt tatcactgac
    40021 catcctgagc taaaggaaga ctttaatatc atcaatatct ctggcgatcc tagcctaaat
    40081 gagcttagtt ggcatcttta ccgcgtggat tatgtgactg atctgtatca accgctcatg
    40141 gaaatggctg atctggtagt gactcgcgga ggctctaaca cactttttga attattagcg
    40201 atgagaaagc tccagcttat tatcccactt ggcaaagagg ccagtcgagg tgatcagctt
    40261 gagaatgctc attattttac aacaaggggc tatgctgagc aattattgga gcaggaattg
    40321 accctgcctc attttcaaga gaaagtgaga gaagtctttg ctaagcaatc ggactattta
    40381 tctgcaatga agagctctag cgagctccaa tcaccagaaa gcttttacca gcttttaagt
    40441 gccgacatta gctccgcgac aaaggaaaat taaatggcag ataagacaaa acattcagaa
    40501 gaaaaagccg ctttgaccga atggcaaaag cgtaatattg aatttctcaa caagaagcag
    40561 cagcaggctg agaaagacaa aaaactaaaa gaaaaattat taaatgagaa aatagcgcaa
    40621 gctcagggag aggcagcttc aaaggctgac caagaagata cagatgaagc tgaggagaaa
    40681 actgaggtaa gccaagcggg tactgatgag ggtgagccgc tgccagaagc atcagagcag
    40741 gaagtcccct ccccaaaaga caagccatta aaagtcccca aagaaaaaag tccaaagcag
    40801 caggcacttc aaaagggctg gcctgtattg ctggtgtcgt ttgtggtttt gtgcctgtcg
    40861 atttttatga tcacacccta tagtaaggtc aaggatttct ccgtcaaggg caataaaaaa
    40921 acaagcgttg aggacttagt tagagacagt gggatcaagt catctgatta ctggattact
    40981 ctattagcct ctccgggttc ttatgaaaat gcggttttaa aagccaatcc ctgggtgaaa
    41041 aaggtggctt tgcgttacgg ctttcccaat catttccgct ttgatgtgac agagtttgat
    41101 attattgcct acgctcaggt agctgaaggg tttcaactga tcctagaaaa tggcaagcga
    41161 gttgctgctg tcaagcaggc tgctttgcct aaatcctttt tgattttaaa tcttgagcat
    41221 gaaaaagaga ttcaagatgt cattaatcgc ttgaccaaaa tcccaagtga cctagtcaag
    41281 gctatcaaat cagtgtcatc ggccaattca cagacaacta aggatttgct gcttcttgaa
    41341 atgcacgatg gcaaccttat cagggtacct cggtcacagc ttgagctaaa gctgccttat
    41401 taccaaaaaa tcaagaagaa tcttgatact gctagcattg ttgatatgga ggttggtatc
    41461 tatacgacca ctgctgaaat tgaaaacatg cctgaggtgc cagcgtctgc tcaagcttct
    41521 caggcagata agcctgctga ggcttcacca gagcagggtg aagagcaggc cacacaggag
    41581 cagcctagcc ctgaaacacc tgctaatcct gaggccacaa atccctcagt cgcccagcct
    41641 actgagcagg caaatcaaca gtaatcgttt agggtaagag aagggggcaa aaaagcattt
    41701 aaggctctta aattaggccc ttgttgaacg gcaaaaaaac attaagttta tataacaaaa
    41761 aacgtaaaat ggtaacattt tacgtttttt tatgatataa tattccctga ataattctgc
    41821 tttttagcag tgtttttgaa tagtaaaagt ttggaaagta agtgaggtcg agtgaatggc
    41881 tagaaatggc ttttttactg gtttggacat tggaacaagc tcgataaagg ttttggtagc
    41941 agagtttatc tctggcgaga tgaatgttat tggtgtgagc aatgttccga gtactggcgt
    42001 aaaagatggc ataatcattg atatagaggc agcagccgct gctattaaaa ctgcagtaga
    42061 acaagctgaa gaaaaagcag gaatgacaat tgaaagggtc aatgttgggc tgccagcaaa
    42121 cctccttcaa attgagccga cacaaggcat gattcctgtt cctagcgaat caaaagaaat
    42181 caaagatgaa gacgttgata gcgttgttaa gtcagcacta actaagagca ttactccaga
    42241 gcgagaggtg atttccttag tccctgaaga gtttattgta gacggctttc agggcattcg
    42301 agatcctcgt ggcatgatgg ggatcaggct tgaaatgcgc ggtctgattt acactggacc
    42361 aagcacaatc ctgcataact taagaaagac agttgagcgt gctgggatta aggttgaaaa
    42421 catcatcatt tctcctttgg caatggctaa ggcggtgtta aatgaaggtg aacgtgaatt
    42481 tggtgctacg gtcattgaca tgggtggagg acaaaccacc gttgcctcaa tgcgagcaca
    42541 ggaattgcag tacaccaata tctatgcaga gggtggcgag tatatcacaa aggatatctc
    42601 taaggttctt aaaacgtcaa tgtcaattgc agaggccttg aagtacaatt ttgggcaggc
    42661 tgatatggca gaggcaagct tgactgacac tgttaaggtt gatgttgttg gcagtgatga
    42721 gccagttgag gtaacagagc gttacttatc agagattatc tcggctcgtg ttcgccatat
    42781 tctagatcgt gttaagcagg atttagaaag aggacgcctg cttgatttac ctggtggcat
    42841 tgtgctgata ggtggcggcg ccattatgcc gggcgtggtt gaggttgctc aagagatttt
    42901 tggaaccaat gttaagcttc atattccaaa tcaggttggt attcgtaacc caatgtttgc
    42961 caatgtcatt agcttggtcg agtacgttgg tatgatgtca gaggtggacg ttttagcgca
    43021 aaatgctgta tcaggcgagg aattgctaag acgtaagccg atcgacttta ctggccaaga
    43081 agcttacttg ccagactaca atgagactag gggatttgaa ccggctccta attatgagca
    43141 gcaagtgccc caagcagact acgagcctca agaacccgct gaaccaaagc aaaagatttc
    43201 agagcgtgtt cgtggcattt ttggaagtat gtttgattaa aagtaataaa gtgaggaaat
    43261 aaaatggcat tttcatttga tacggcatcc attcaaggtg caatcattaa ggtaatcggt
    43321 gttggtggag gtggcggaaa cgctattaac cgcatgattg atgagggggt tgcaggtgtt
    43381 gagtttatcg ctgcaaacac tgatattcag gcattaagct catcaaaagc agaaacagtt
    43441 gttcagcttg gtcctaaatt aactcgtggt cttggtgctg gaggtcagcc agaggttggt
    43501 cgtaaggcag cagaggaaag cgaagaggtt ctcacagaag ctttgactgg cgctgatatg
    43561 gtctttatca ctgctggtat gggtggaggc tctggaacag gagcagctcc agtgattgct
    43621 cgtatcgcta agagcctagg agccttgact gtggcagttg taacacgtcc atttggcttt
    43681 gaaggcaaca aacgcagtaa ttttgccatt gaggggattc aggagctaag agagcaggtt
    43741 gataccttat tgatcatctc aaataataac ctgcttgaaa ttgttgacaa aaagacacca
    43801 ttgcttgaag cgcttagcga agcagacaat gttttgcgtc agggtgtaca agggattact
    43861 gatctgatta caagccctgg cttgattaat cttgactttg ccgatgttaa gactgtgatg
    43921 gcaaataaag gcaatgcact tatggggatc ggtattggtt ctggtgagga acgtattgta
    43981 gaggcagctc gtaaggctat ctactcacca ttacttgaaa caacaattga cggtgctgaa
    44041 gatgttatcg ttaacgtgac aggtggactt gatatgaccc tcacagaggc tgaggaggca
    44101 tctgaaattg ttggtcaggc agcaggtcaa ggcgttaaca tctggctagg aacatcgatt
    44161 gatgactcta tgagagacga aattcgcgta acagttgttg caacaggtgt tcgtcaggat
    44221 aaggcggagc aagcctcagg atttcgtcag ccacgcacct acactcagtc taacgctcag
    44281 caggctgctg gagcacaata tgcttcagag caggtgagac agactgcgca gccaagcttt
    44341 gatcgtcgtt catcaagctt tgattttgat atgggtgaaa cacgtgagat gcctaagtct
    44401 cagcaagcta tgccagctca tggccacaat cataatcagg gctcagcttt tggaaattgg
    44461 gacttacgtc gagacaatat tgctcgtcca gcagaaggtg agcttgacaa tcaattgaac
    44521 atgtcaacct tctcatcaaa tgatgacatt gatgatgaat tagaaacacc accatttttc
    44581 aaaaatcgtt aatgatggat ttacaaaaaa ataaggatat tgtttttgaa aatattcgct
    44641 tagccactca ggcagccaac cggcctgaaa acagtgtgtc agttatcgct gtcacaaaat
    44701 atgtggacaa ggcagttgca ggtcagctga ttgatatggg gattgagcat atcgctgaga
    44761 accgtattga taagtttcta gataaatatg aagccttgaa agataggcaa gttacttggc
    44821 attttatcgg tactttacag cgtcgaaagg taaaggaagt gattaataag gttgattatt
    44881 ttcatgcctt agattcagta aaactggctt tagaaattga aaagagagct gaccaccctg
    44941 tgaagtgttt tctacaagtt aatatttctg aagaagaaag caagcatggt tttaagattg
    45001 ctgagcttga tgctgctatt gaggaaatca gcaagatgga aaagcttcat cttgtcggta
    45061 tcatgacaat ggcacctatt gatgccagtc agcaagagct tagaagcatt ttccaaaaag
    45121 caaatcaatt aagaaaaaac ttgcagtcaa aaaagagaaa gaatatgccg tttacagaat
    45181 tgagtatggg catgagtaac gattatccaa ttgctattca agaaggctca acctttgttc
    45241 gtattggaac atctttcttt cactaaatgg agaataagat ggcaattaaa gacgcattta
    45301 ataagatgat ttcttatttt gatactgatg gggtcagtga agtagaagag gagctatcct
    45361 ctaaaaagca agaagagcct gtgactaaat cacaacagac cagcagacct aatcagcagc
    45421 aacaagcagc tagagcgagt cagccccagc agcctaagca ggctagacct cagatgcaag
    45481 ctcagcaaag accacaatca caatcaagag ctgcctatgc tgagcgacca tatcaaggtc
    45541 aaagtcaagc acgtgtttct catgactaca atgacagaag ggcgacgtca gccccgtctg
    45601 cttctagtcg tcgtgagcaa tatcagcatg ctgctcatca agagcaaaca actattgcct
    45661 tgaagtatcc tcgtaagtat gaggacgccc aagaaattgt tgatcttttg attgttaatg
    45721 agtgtgtgct gatcgatttt caatacatgc tagatgctca ggcaaggcgt tgcctagatt
    45781 ttattgacgg tgctagtaag gtattgtatg gtactctgca aagggttggt tcttccatgt
    45841 atctgttgac cccatcaaat gtatctgtta atattgaaga gatgaatatc ccaaataatg
    45901 gccaagatat tggttttgat tttgatatga agagacgcta gtgtgatgat ttttatactg
    45961 ttgatacttc taaagctaat taaggtttat tcctatttgc tgctagtcta tgccttactg
    46021 tcttggtttc ctggagccta cgactcttgg cttggcaggc tggtcagcga tatagtagag
    46081 cctatcttaa aaccctttag atcattgaac ctacagtttg cgggcttgga ctttactatt
    46141 tacctagtga tgattggtct aaatgtttta agtgagatct tgataagagt gttgatctca
    46201 tgactgttca aacaatgctt tatcagcatt ttcagcctga tgaacaccca tttattgaaa
    46261 gaatgcttga cttgatcgct cgtgttgagg ctaattattt attagaggtt actgattttt
    46321 taaatccgcg agaggtcacg attttaaaag gcttagtcgc agcaaccaat ctgcagtgct
    46381 ttagctctac tgattattat cctagtgaat atggtcgtgt gattgttgct cctgactatt
    46441 attgtctaga taaggcagat tttgacttgg ctttgattga ggtgacctat aatgctaagt
    46501 ttaatcagct gacacatgca cagattttag gcaccttaat taatgaattg ggaatcaaaa
    46561 gagccttact tggcgatatt tttgttgaga taggtcatgc tcaggtcatg attaatcgac
    46621 agctgttaag ctattgttta ggaacgattg ctaaaatagc aaaagctagg gtcaagctca
    46681 aagaaattga tcttgatcag ctgttaaatc tgacagctaa tcagcaggtt ctgactgata
    46741 taatggtatc tagtctacgc gttgatcgct tgattgctac cgtattaaag caatctagaa
    46801 atcaggcgat aaggcttgtt gaagcaggca aggtcaaggt taactatcag cttgtcacta
    46861 aagcctctca gcctgtagct gttggtgatt taatcagcat tcgtggctac ggtaggttta
    46921 gcatactaac agacaatggc ttcacaaaaa atgggaaata taagctaaca cttagcaaaa
    46981 tgatgcgtaa ataaggagat ataatggcac ttacagcact agaaattaaa gataaaacgt
    47041 ttaagacaaa gtttcgtggc tacagtgaag aggaagtaaa tgaatttctt gagattgttg
    47101 tagacgatta tgaggctttg gttcgcaaaa atcgtgataa tgaagctaag ataagagagc
    47161 ttgaagaaaa gctgtcttac tttgatgaga tgaaggaatc attgagtcaa tctgttatcc
    47221 tagcccagga aacagctgaa aaagtgaaat cctcagcaaa tgctgaagca accaatttgg
    47281 tcagcaaggc aacctatgat gctcagcatt tacttgatga gtcaaaagca aaggctaacc
    47341 aactgttgcg cgacgcaaca gatgaagcaa agcgcgttgc tattgagaca gaggaattaa
    47401 agcgccagac acgcgttttc catcagcgct tggtttcagc tattgagtca cagctaagct
    47461 tatccaattc gcctgagtgg gacgaattgt tgcagccaac agctgtctac cttcaaaact
    47521 ctgatgcagc ctttaaagag gtggttaaaa ctgtccttaa tgaagatatt cctgaggctg
    47581 atgacagcaa ttcctttgat gcaacacgtc agtttacacc agaggagcta gaggagctgc
    47641 agcgtcgtgt tgaagaaagc aataaggagc tagaagccta tcaggtgcag cgagaagagc
    47701 aagctagcga gcctgaagtg aacctaagcg agacacagac ctttaaattg aatatttaat
    47761 cataagaaaa acaggattga atgcccaaaa tcacagcaag taggagatga tgagagtcct
    47821 atattccctg agcatgacaa ttatcatttt cttcaatcat cactgaatga cagtaagtga
    47881 cgagggaggc tcaccttacg agcaaagagg gaacagcaaa agggatttta ctgttctgaa
    47941 ttaaggtggt accacgagct ttcgtccttt ttgagacggg gctttttttg taattctgat
    48001 aagatattga ctaaaaggag tttgacaaga tgaaattaaa agaaacactt aacttaggca
    48061 aaacggcctt tccaatgcgt gccggtctac ccaacaagga gccacaatgg caaaaggctt
    48121 gggacgaggc tgagatttac aaaaaacgtc aagccttaaa tgaaggcaag cctgcctttc
    48181 acctgcacga tgggcctccc tatgcaaatg gtaatatcca tgtcggacat gcgctgaata
    48241 aaatttcaaa agacattatt gtacgtgcca aatctatgtc aggctatcaa gcgccttttg
    48301 ttccaggttg ggatactcat ggccttccta ttgagcaggt cttggctaag cagggggtta
    48361 agcgtaaaga gatggatctg gctgactatc ttgacatgtg tcgtcagtac gcgttaagtc
    48421 aggttgataa gcaaagagac gactttaagc gtctcggtgt atctgctgat tgggacaatc
    48481 cttatgttac cttagatcca agctttgaag ccgatcaaat tcgtgtcttt ggtgcgatgg
    48541 ctgataaggg ctacatttat cgtggggcaa agcctgtgta ttggtcatgg tcctctgaat
    48601 ctgctcttgc tgaggcagaa atcgaatacc atgatattga ttctacatcg ctttactatg
    48661 ctaatagggt taaagatggt aagggaatcc ttgatactga cacctatgtt gtggtttgga
    48721 cgaccacacc atttacggta acagcttctc gtggtctaac agttggacct gatatggatt
    48781 atgtggttgt tagacctgca ggttcagacc gtaactatgt ggtggcagaa ggactgctag
    48841 acagtctggc tgctaagttt gcttgggaat catttgagat tttggccaat cataagggct
    48901 ctgacttgga atacattgta accgagcacc cttgggacag tgaggttgat gagctagtca
    48961 ttcttggcga tcatgtgacg ctagattcag gtacaggtat cgttcataca gcacctggct
    49021 ttggtgaaga tgactacaac gttggtatga catatggact tgaggttgca gttacagttg
    49081 atgagcgtgg tttgatgatg gaaaatgcag gtcctgattt tcatggtcaa ttttatggca
    49141 aggtaactcc gattgttatt gaaaagcttg gagacctatt gcttgctcaa gaagtgatca
    49201 accactccta tccatttgat tggcgcacga aaaaaccaat tatttggcgg gctgttcctc
    49261 agtggtttgc ttctgtgtct gacttccgtc aagagattct agatgagatt gacaaaacaa
    49321 cattccaccc gacatgggga aagacacgac tctacaatat gattcgtgat cgtggcgatt
    49381 gggtgatctc tcgtcagcgt gcttggggtg ttccactgcc tattttctat gcagaggacg
    49441 gcacagccat tatgactaag gaggtaactg atcacgtcgc agatctgttc caagagcatg
    49501 ggtccattat ttggtggcaa aaagaggcta aggagctttt acctgaaggc ttcacacacc
    49561 caggctctcc aaatggggta tttaccaaag agacagatat catggacgtc tggtttgatt
    49621 cagggtcttc ttggaatggt gtgatgaatg ctcgtgatca tcttgcttat ccagctgacc
    49681 tctaccttga gggctccgat caatatcgtg gttggttcaa ctcatcactg attacctcag
    49741 ttgcggttaa tggtcatgca ccgtataagg ctatcctatc acagggcttt gtccttgatg
    49801 gtaagggtga aaaaatgtct aaatctaaag gaaatatcat ttcacctaat gatgttgcaa
    49861 agcaatatgg tgctgatatt ctccgtctct gggtagcttc tgttgataca gataatgatg
    49921 tgcgtgtgtc aatggatatc ctaggacagg tctctgaaac ctatcgtaaa atccgtaaca
    49981 cgcttcgctt cttgcttgct aatacatcag acttcaatcc acatacagat aaggtggctt
    50041 atgctgagct tgctgctgtt gataagtaca tgaccatcaa gtttaacaag ctagtaggag
    50101 ctatcaatac tgcctatgag cgttatgact tcatgacgat ttacaaggct gtggttaact
    50161 ttgtgacggt tgacttatct gctttctacc ttgattttgc caaagatgtg gtctacattg
    50221 aggctgctaa cagcctggca cgtcgtcgta tgcagactgt cttttatgat attttggtta
    50281 atatcactaa gctattgact ccgatccttc cacatacggc agaggaaatc tggtcatatt
    50341 tagagcatga gccagaagac tttgtacagc tatcagagct gccacaggct cagacttttg
    50401 ataatcaaga tactatccta gaggaatggg aagcctttat gacgcttcgg gcacaggcgc
    50461 aaaaggcttt ggaggaagca cgtcatgaca agattattgg taagtcctta gaagctcatc
    50521 tgacaattta tgcaagtcca gaggttaaga cactgttgac agctctagat agcgatattg
    50581 cactgctatt gattgtctct cagctaacca ttagtgagga gccagctcct gagaatgctg
    50641 tcagctttga tgatgttgcc tttacggtag ctcgtgcgca aggagaggtt tgtgagcgtt
    50701 cacgtcgtat cgatccaacg accagaatgc ggtcttataa tgcctttgtt tgtgaccaca
    50761 gtgcgaaaat tatcgaagaa aacttcccag aagcagtagc agaaggcttt gactcagctg
    50821 ctaattaagc aactaacagc tctgttcccg agttaaataa gcattggcgt gcttttgcca
    50881 atccagcagc aaggtgctag tcggtctggg cgtacctgcc ttactaggga ctctttgtgt
    50941 gggagctgat aagtgacctg ccttgagctt ggcaggtcta ggcttcttta taggttcacg
    51001 atttacgatt gactgggctt agagaagggc tagtcctgct aggcggcatt ggatatgaac
    51061 tgagtagtca tcatagctat aaaaaaacaa gcgcagactc acgtcagctt aatcgtgagc
    51121 ggcgcttgtt ttttcttggt tggggggtga aggcgaggag ctattaaagc taatattaag
    51181 cgatcaaaaa agcctagacc actagtcatg ttgtctaagc ttcagctgtt agagaggagc
    51241 tttctgagtg gaaggtagcc tatgctgata ggtgctgcct tagcctttta gcagtagtat
    51301 taaggctaga cagacgtctg gaaggaaatt tcaatcaaat tattggtgtg cagggttttt
    51361 gagtgacctg gaatcacaat agattggtca atcttacgct ttaagaaaaa ttcgcgaatc
    51421 acttcaagct cgtcctcttt gatggcacga tatttatttg aaatgagtag ctcataatgc
    51481 ttgggtgctt gcgtaaagat gacgtcagtg ttaccagctg agtaaacttc aacgaggtga
    51541 gcatctgtat tttgcagctg atttctgaca agctcggggt gactgctggt ggtattaata
    51601 agtctcataa atcttctcct gactattttt acttttatta tagcactatt tttaaattga
    51661 ttacggattt taatggtgct ttttctgcca ttcttcgacg ccccatctgt ggctatcacg
    51721 ctttaagact gttatggcgt ccgcaatagg aagaaaccaa gccagatggt taaagtcttc
    51781 caagggcttt gagatagctt ggaatgatgt cacctcgtac aggtaggcag gattatagta
    51841 gtaggtatcg cggtgacgag aatagaagta ttcgtctgct tgaccataat aataaccaat
    51901 atcagcagca aatcccagct cctcaactag ctcacgctcc agtgcctgta gctggctttc
    51961 accagcctct atttctcctc ctggcaaaaa ccaagcacca tttggagcct gcactaggat
    52021 aatctctgtt ttagccgagt taggaatcac tgcatagaca ccgtaacgtg cggtgtaatg
    52081 ctggtcatct atcttatcac caaatattgg aacggtcata tcgcttctcc tttgttttat
    52141 tatactaaat ttttggtcat tattctcata aaactgtaga tttatcaaaa atgtttcata
    52201 aaaaaatgct cgtcaaaaag agagaaaatg ctgtctgctt ttctctctgc ttttctctct
    52261 gctttttggt atgccctgtt agtccgcctg cttcgcctga gatttgacta caggcttgat
    52321 tataatgtgt ccattagagg tcaagacagc tcgcatgtct ttttctgctg ggtgctcaag
    52381 gtagaagtca gtaatggcgt cctcaatgta gtcctgaatg gtgcggcgca atggtcgtgc
    52441 tcccatctta ggatcatagc ctagctcaac gagcttttct ttgacctttt gggtgacatc
    52501 aaggcgaatg ttattgtgag caaggcggtg gttaacatca tcgagcatta aatgaacgat
    52561 atgtaaaaga ttgtccttgc ttagtggctg aaactcaata atgccatcaa agcgattcat
    52621 gaactcgggg ctaaagaaat gactgagctc tcctaaaaca gagtttgtcc gcccttctct
    52681 agcagcgcca aagcctactg aggcctctgt tttgccagtg ccagcatttg atgtcatgat
    52741 gataatagtg tccttaaagc taacggtacg tccttgtccg tcggttaatc gtccgtcatc
    52801 taggacctgt aaaaacatgt gcatgacatc agggtgagcc ttttcgatct catctaacaa
    52861 aatgagcgag taagggttgc ggcgcacctg ctctgttaac tgacctgcct cctcatagcc
    52921 gacgtagccg ggaggggcac cgacaagctt agccacagcg tgcttttcca tgtattcaga
    52981 catgtcaaag cgaatcatgt tatcagcaga gccaaaaagc tcaatggcta attgcttgga
    53041 aagctctgtt ttaccgacac cagttgggcc aacaaagagg aaggagccga taggacgatt
    53101 tggggctccc agtccaacac gattacgacg gatagctttt gcaattttat caacagcatc
    53161 gtcttgaccg ataacatgct ttttgagatc ggcggccaga ttgactagct gtgattgttc
    53221 cttttccttt aaatcaccaa ctggaatatt ggttttttgc tcaacgattg cttcgatggt
    53281 cttgtcagtg atgattggaa tatcctgctc atctagcttt tgagcctgca tttctttata
    53341 tttggcgatt tgatcgcgga aataggctgc tcgctcataa tcctcatcac gtgtggcttg
    53401 tgtcttgagg ttttcagcct caatcaaacg cttatcaatg tctttggggt caacaaagtt
    53461 aagggttagg ttcatctttg agccggcttc atctagcagg tcaatggcct tatcaggcaa
    53521 gaagcggtct tgaatatagc ggttggagag gttagcagct gcttcaatag ccgactggct
    53581 atatttgaca tggtgatagt cctcatattt gggttggatt ccttttagga tagtgattgt
    53641 ttcttcaacc gaaggctcgt ccaccttaac cggctgcatg cgtcgctcaa gggctgcgtc
    53701 cttttcgatg atgcgatatt cattgagagt ggtcgctccc actaattgaa gctcaccacg
    53761 agcaagtgct ggctttaaaa tatttcctgc gtccatgctg ccgtcaccaa ctgcaccagc
    53821 tcccacaatt tcatggattt catcaataaa tagaatcacg tcatggcgct tgcggatttc
    53881 ctccatgagc ttttgcatgc gctcttcaaa ttggccacga atacctgtcc cctgaacgag
    53941 gctaaccaca tcaaggcgaa tcacctgctt actctgtagc ttttgtggca catcgccatc
    54001 aacgattttt tgagcaaggc cttcaacgac agcagtctta ccaacacctg gttctccgat
    54061 taggacaggg ttatttttgg tacgacggtt gagaatctcg atcacgcgga taatctcatc
    54121 gtcacgtccg atgacaggat caatatcacc acgcttagcc atttcagtga tattaatgcc
    54181 gaattcctca agcaaacctt tgttagcctc ttgtgctggc tgtgtgtgat tgggacggta
    54241 gccattgtga cctccgccat tatggccgcc tgattgggta ggtggtgtat tgggcaattg
    54301 accgaaggct ctaaaattgt tcaggtcacc aaaaaagtca tcaaagaaag ggttttgaga
    54361 aggctgctgc gccttttggt tgccattata gcctcctaag ataggatttt tagggtctgt
    54421 tttcatgatt tggtagcaat tttgacagag gtcaatctgc ctttgctttc cgttaatgct
    54481 tgtataaaga tgaatggttg attcgtttaa attacagttt tgacaaagca tatcatacct
    54541 ccaaggggtt atctaaaaag tcaaggtcat ttagtcaaaa atggtcaaac tttatagtca
    54601 tattatagca ccttaggctt ggaaatcaag taaaaagctt cattattagc actttcaggt
    54661 atagagtgat aatctctata aatcttgctg ctcattggtt caaaaaagtc gtcaaagggg
    54721 ataaaataaa gagaaaatgg ctacttttct tgtttgtttt cgatgattta tgttaaaata
    54781 tatagggaca ataaacgaat aggagaaacg aaatggaatc acatttagtg agaatcatca
    54841 accgtctgga gctgatggta acagatggcg gtaatttaaa gagaaacttt gagcgagatg
    54901 gtgttgttgt tgcagaggtt gcatttgtca acgatcctga aaatggtcca gtctttattt
    54961 tacgtgatat tgaagcgcgt gagtcatatt catttgatag catcgatttg attgcgatgg
    55021 aaatttacga tttgttatat taagctattg atgatgacat gggcttgctg ggaggcaggt
    55081 cagacagagg acaagctggt gatttactgg tttgttttta ttatccctta aagcctcaag
    55141 acagctccag gaaaggcctt tctcctatgg tctttctagc cggtagggct tgatagtgat
    55201 taatagtgat ctgctctagc acggtcttga gcttttactg tcagaggctt gtgaccttag
    55261 ccactcgcag taaagggtac tggcccagta agcaaggtag gctaagtatc aatgtgaagt
    55321 tctaaccttg atcttagtga aatatttttg aggtgaatta agatgttaaa agtccttaga
    55381 atgctcattt ctaagggttt tgttgtgtct agctgttggt gtttgaaaga gcggtggtat
    55441 gataaagaga ggtcagaaaa gacctctctg atgtttgtga ttagctgtta gctattgcca
    55501 taggggaaag acacaatagc tagcttagct tttctttttc tttaggttta ggacgcctgc
    55561 gctagtgatg acgctaaggg ctgcaagggt gaagaatggg tgatttgtct cccctgtagc
    55621 tggtagcgtg ctcttttgag ctgctggtgc tgacttaggc gctggtgctt taggctgagc
    55681 tgatttttct ggagcctttg gtgcaggtgt cttttcaggt gcttttggag ctgatggttt
    55741 tgtatctttt ccttgatcac cctttggttt ttgctcgcct ttttcgccgc gttgtccttg
    55801 ctcgcctttt tcgccgcgtt gtccttgctc acctttttca ccgcgttgtc cttgctcacc
    55861 tttttcaccg cgttgtcctt gctcaccttt ttcaccgcgt tgtccttgct cacctttttc
    55921 accgcgttgt ccttgctcgc ctttttcacc gcgttgtcct tgctcacctt tttcaccgcg
    55981 ttgtccttgc tcaccttttt caccgcgttg tccttgctcg cctttttcgc cgcgttgtcc
    56041 ttgctcacct ttttcgccgc gttcgcctct gtcaccctta gggccggctg gtccttgttc
    56101 acctttagga cctgtttctc cggtttcgcc tttatctcca cgtggtccca taggcccaac
    56161 aggaccttgc tctccgcgtt cccctctagg tccggcaggc cccacaggtc cctgaggacc
    56221 acctttttta gcttgtagtt ctaagttttg taagtaggtt tgcatgaatt gtcttaatgt
    56281 atgtaggtat actcttactt cgccatctcc gagtccgtcc ctaattagtt cagctggatc
    56341 tggataggac tctaatcgcg tataatcttc agctcgggca tttccagctg ttcctaggct
    56401 ggccattgtt gctagggcaa tggctgctga gcagacgctg tacttgcgta ttgttttttt
    56461 catctttctc tcctttgatg atagtatcat tactttttca aaattctttc ccgaagaaga
    56521 gtttaacatg gtagcttgct atgagaaaca gctaggcgcc actttgtctc cgtagttttt
    56581 ttaattcaat gctgaatcgt ctgattttat cagagggtta ttgtttttaa aggcgaggag
    56641 ttgctttgct cagctagtct agcaagttca caggtcagct tatgtttctt atcaagcttg
    56701 tttgtttttg agaatatttt tcgataaaaa gatgttgtat taatattcat gttatagtat
    56761 aattatattc gttgccatga ctttatgaat gttaggagat aggaatggat tttacctttt
    56821 tacccaaata ctgggcttat ttcaattatg gtgtgcttgt aaccatgatg atttcagcct
    56881 gtgttgtctt ttttggcacg attataggtc ttttagtgac cctgataaaa cgcagtcata
    56941 tcaagccttt gtcttggctt gtcagtcttt atgtctggat ttttcgtgga acgccgatgg
    57001 tggtacagat catgattgct tttgcttggc tgcatttcaa cgatctgccc attgtaggct
    57061 ttggtgtgtt ggatttggat ttttcaagac tgcttcctgg tattattatt atttccttga
    57121 atagcggtgc ttacatatct gaaatcgtca gggctgggat tgaggcggtg ccaaaggggc
    57181 agctggaggc tgcttactct cttggtatcc gtcctaagaa cgccatgcgc tatgtgattt
    57241 tgcctcaggc ctttaagaat attttgccgg ccttgggcaa tgaattgatc accattatca
    57301 aggatagtgc cttgcttcag acgattggtg tgatggagct ttggaatgga gctcagtcgg
    57361 ttgtgacggc gacctatctg cctattacac ccttgctgtt tgcggccttt tattacttga
    57421 tgataacaac aatattgtcg caattattag gctgcttgga gcgcaagcta gcacagggag
    57481 ggagataaga tgactgagac agtgatttcg attcgtcagt tgcataagag ctttggcaag
    57541 catgaggtgc taaaaggaat agacctgacc attaatcagg gtgaggttgt ggtgattatt
    57601 gggccatctg gctcaggaaa gtccacgcta ttgcgcacga tgaatttgct tgaggtgcca
    57661 acaaagggac acatcagctt tgagggcgtc gatattacgg ataaggcaaa tgatattttc
    57721 aagatgcgtg agaagatggg catggttttt cagcagttta atctgtttcc caatatgaca
    57781 gtgctggaaa acatcaccct gtcacccatc aaaacaaaag gaatgtcaag ggctggcgcg
    57841 gagcagagag cttatgagct gcttgagcga gttgggctga gagataaggc tgctgcctat
    57901 ccggcaagct tatccggtgg tcagcagcag cgcattgcga ttgcgcgcgg cttggcaatg
    57961 gatcccgatg tgctgctctt tgatgagccg acctcagcgc ttgaccctga gatggtgggt
    58021 gaggttttgg ctgttatgca ggatttggca aaatcaggca tgacgatggt tattgtaacg
    58081 catgaaatgg gctttgccaa agaggtggcg gatcgcgtga tttttatgga cggtggtctt
    58141 gtgattgaag agggcagtcc agttcaggta tttgaagctc ctaaggagga gcggaccaag
    58201 gactttttga gcaaggtatt gtcatagctg gcgcagctaa agggcagcat gtcacctcaa
    58261 ggtctggcta ttagtcaatt ggctgtttgt tttgggcatt ttgtttgtaa aaggcttaga
    58321 aagtctggtt ggtgctgtag ccatatctgg ctttgctacg cttgggctgc tagctggtca
    58381 gtgggtatca tagtgattgg aggtgtggtc tctttattgg tcaacattgc tgtggcaggc
    58441 tagcacaggg gctttgcttg ttgtgctggg taaggggttt catttgcatg actgttaaca
    58501 ttgcttaatt gatgaattag gttgactttt gttttattgt ttgatactat tcaggtaagt
    58561 ctgtcattag aaagcgcttt gcttttttga tgatggaaat catgatcata tgatcacgtc
    58621 ttaggtaata tgttgttgtc aacatggtgg tctgaaagta ggaggataat atggactaca
    58681 aagctgttta tcaggagtgg ctgcacaatg attttttcaa tgaagaaatc aaggcagatt
    58741 tagaggcgat taagcatgat gaggctgaga ttcaagaccg tttttataag gtgcttgagt
    58801 ttgggacagc aggacttaga ggaaagctcg gtgctgggac caaccgtatg aatatttaca
    58861 tggttggtaa ggctgcgcag gctttagcta ataccattat tgatcatggg ccagaggcag
    58921 tctcacgcgg gattgccatc agctatgatg tgcgctataa gtctaaggaa ttcgcagaat
    58981 tgacctgctc gatcatggca gccaatggga tcaagtctta tatctacaag gggattcgtc
    59041 cgacaccgat gtgctcttat gcgattcgtg ccttgaactg tatctctggt gtcatgatta
    59101 ctgctagtca caatcctcag gcctacaatg gctacaaggc ttattgggaa gaggggtcac
    59161 agatcctaga tgacattgct aatcagatag cggttcatat ggacgctatt gagcgctttg
    59221 aggacgttaa gcagataccc tttgaggagg cattggcaag tggtctgacc agctatattg
    59281 atgatagtat agaggaggcc tataagaaag aggttttagg cttgaccatc aatgatactg
    59341 atattgataa gtcagtgcgt gtggtttata cacctttgaa tggcgttggt aatttgcctg
    59401 ttcgtgaggt attgaagaga cgaggctttg atcatgtctt tgtagtgccg gagcaggaaa
    59461 tgccagaccc agatttcaca acagttggtt atccaaatcc agaggtacca aaggcctttg
    59521 cttattcaga aagactaggg caagaagtag gagcagctat tctgattgcg actgatccgg
    59581 actgtgatcg tgtggcacta gaggttcgag ctgctgacgg tagttatgtc tttcttaatg
    59641 gtaataagat tggtgctttg ttgtcctact atatcttttc acagcgtcat gctaggcata
    59701 atcttcctga caatcctgtc cttgtcaaat caattgtaac aggggattta tcaaaagcta
    59761 ttgccgctaa atatgacgtt gaaacggttg agactcttac aggctttaaa aacatctgtg
    59821 gtaaggctaa tgactatgac atcacaaagg agaagaccta cgtctttggc tatgaggaaa
    59881 gcattggttt ttgttacggt acctttgtgc gtgataagga cgcggttagc gcctcaatga
    59941 tggtggtaga aatggctgcc tactacaagc aaaggggtca gtcactctta gatgtgcttc
    60001 aagacattta caaggaattt ggctattaca atgagcgtca ggtagcgcta gagctagagg
    60061 gtgttgaggg gcagaagcgt attgcacgta tcatggagga ctttagaaat gagcctattg
    60121 agcatgcagg tgctatgagc ttgaagacca ttgtagactt taaggacggc taccttgatt
    60181 ttccaaagca aaattgtttg aaatattatt ttgatgatgg gtcatggtat gcgctgagac
    60241 catctggaac agagcctaag atcaagcttt acatctatac tattggtgaa acagaggcag
    60301 acagcattgc taagctagac gctattgagt cagcttgtca agcaaagatg gacagtgtca
    60361 gctaattgtt caagctctgc aacagaaaat cagctaatca ataagcaaaa aggaaaagga
    60421 agtgacagtg cttccttttt tcgttataat agttaaaaaa ttagcaagga gtgcatatgg
    60481 tacagattat tgatgggaag gccctagcac agaaaatgca ggcagcattg gctaagaagg
    60541 tagagagctt aaaggcagaa aaaggaattg ttccaggcct tgttgtcatt ctggtaggag
    60601 acaaccctgc tagtcaggtt tacgtccgta ataaggaacg cgctgcctta gcagcaggct
    60661 ttaaaagtga aaccgttcgc ttgtctgatt cagtctgtca ggaagagttg atagagctca
    60721 ttgagcaata taatcaagat gatacgattc atggtatttt agtgcagctt cctcttccgc
    60781 accatattaa tgacaaaagc attatccttg ctattgatcc taaaaaggac gtcgatggct
    60841 ttcaccctat gaatacaggt catctgtggt caggtcgtcc gaatatggtc ccttgtactc
    60901 cggcagggat tatggagatg tttcatgact atggtatcga acttgaaggg aaaaatgctg
    60961 ttattgtcgg gcgctcaaat attgttggga agcctatggc gcagctactg ttggataaaa
    61021 atgctacggt aacgcttacc cattcgcgca cgcgccgact ggcagatatt tgtcgtcgtg
    61081 ctgatatctt gattgttgct attggtcagg ggcattttat cacaaaggag tttgttaaag
    61141 agggtgctgt tgttatagat gttggtatga atcgtgacgt caatgggcga ttgattggag
    61201 acgtcgcctt tgatgaggtg tcagagctgg ctagcatgat tactcctgtt ccgggtggtg
    61261 ttggaccgat gaccattact atgcttttgg agcaaaccta tcaagcagct ctaagaaggg
    61321 tgagtcaatg attatagatc aatcgtttgt tgctagggtt gttgttccgc ggcaggctga
    61381 ctcccataag gggagttacg gcagagtact gttagtaggt ggcttgtatc catacggtgg
    61441 tgctattatt atggtagcgc tggcctgtgt tcatagtggt gctggcctag taactgttgc
    61501 aactgataga gaaactattg ctgccttgca tagtcatttg ccagaggcga tggctattgc
    61561 ggtagatgat gaggaattac tgttatctca gctaggtatg gcagacctga ttttgattgg
    61621 tccggggctg tcggagaata gcagagcagc taggctgttt gaattggtcc ttgcacatgt
    61681 cgctgatcat caggtattgg tcattgatgg ctctgcctta aggcttttag cgaaaagggc
    61741 agctgatgtt aagcagctga ggtgccctct tgtgttaacg ccacaccaaa aggaatggga
    61801 ggcgctgtca ggtttagcga ttgatcagca gtatgatgct gccaaccaag cagctctcaa
    61861 gcattttcca agggctacga ttttggttgc taaaagctca gcaaccaaga tttatcatgg
    61921 caaccagatc taccggctaa gagtgggcgg accttatcag gctacaggtg gtatggggga
    61981 taccttggca ggtatgatag caggaatagc tgtccagttt ccagagtcaa gcttggtggc
    62041 taaggttgct tgtgcgacct atctgcactc tgcgattgct gatgagctgg caaagactgc
    62101 ctatgtggtt ttgccgactg ctattagcta tgagcttcct agatggctaa aggcaatcag
    62161 cacaggccag aagctaggtt gaggctgtgc tgcgaggtcg tttgggaaaa gcggttaatt
    62221 ggtaggcatg acagcagctg gtttcagtcg tttagctatt ttgagtttag agctgctagc
    62281 ttaagactgg gtgctgcttt atgattcaag gaagctatca ttggaaaaac ttgtgtcaag
    62341 ctgtagaagc cctagctggc ttcttttttt gtctcttttt tgctcactat ttatgtggaa
    62401 acatgatata attgcattag tatacagttg gagcagttag gcttcatgaa gtgaaaggta
    62461 aactgatggc agactattta tccgtcactc agctgacaaa atatttaaaa ttgaaatttg
    62521 atcgagaccc ttatctggag cgtgtctatc tcactggtca ggtatctaat ttcagaaaaa
    62581 gaccaaatca ccaatatttt tccttaaagg acgagggagc ggtgattcag gccaccatgt
    62641 gggcaggagc ttataaaaag cttggctttg atttagaaga gggcatgaag ctcaatgtgg
    62701 ttgggcgtat tcagctctat gagccaaatg gctcgtattc aatgatcatt gaaaaggctg
    62761 agccagacgg tattggtgct ttggcgctgc aatttgagca gctcaggcaa aagctggctg
    62821 gtgaaggctt ctttgatgag aggcataagc aggccctgcc gcaatttgtg acaaaggtag
    62881 gtattgtgac gagtccaagt ggggctgtga ttcgtgatat tatcacaacc atctcaaggc
    62941 gttttcctgg ggtgagtatt cttttgtttc caacaaaggt tcagggtgag ggggcagctc
    63001 aagaggttgc tgctaatatt actaaggcta accagcgtga ggatctggat ttgttgattg
    63061 ttggacgcgg cggtggctcg attgaggacc tgtgggcttt caatgaggaa atcgttgttc
    63121 aggctatttt tgagtctcgc ctgcctgtta tttccagcgt aggacatgag acagatacaa
    63181 ccttggctga ttttgtggct gatcgcagag ctgccacccc aaccgcagct gcagagctgg
    63241 cgacacctat tacaaaaaca gatattgtct cttggattgc tgagcagcag agccggtcct
    63301 atcaagcctg tctgcgctat atcagacaag ggcaggagcg ggtggataag ctttcttatt
    63361 ctgttatttt caggcagcca gagaggctct atgatgctta tagtcaacgc ttagataggc
    63421 ttacgacctc cttgatgacc acttttaaag agacattatc aggagctaag caggagcact
    63481 tgattttgga gcatcgttta gcctctgtca atgtacaggc aaggcttgag cgttatcagg
    63541 atcgtctggc aactgcgcat cgtctcttga tagccaatat gaccaatcaa tatgacagta
    63601 agctagcagg ctttgagcga gctcaagctg ccttgctgtc gcttgatacg agccgtatca
    63661 ttgcccgcgg ctatgccctg ttaaaaaagg acggtgtagt agctgcttgt gttaaggaca
    63721 ttaaaaaggg agatcatctt agtattatca tgcgtgatgg tcaattagaa gtagaggtag
    63781 aagatgtcaa cgaaaaaaat atttgaagag cgtttacaag aattagaggc tattgtgacg
    63841 aggctagaaa atggtgatgt gccactagaa gaggccatct ctgaatttca aaagggtatg
    63901 gtgctgtcca aggaccttca aaaaacctta caagcagctg aaaagacact tgttaaggtc
    63961 atgcaggcag atggcacaga gctagaaatg gatgcctaat ggataagcta acaagaatta
    64021 atgccacgat tcatcagtat tatgacaggc agtctactgt ttcagcagat ctggaggagg
    64081 ccattttata ttctgttgat ggtggaggaa agaggctccg tccactcatg ttattggagc
    64141 tgctagaggg ctttggtctt gccttgacag acgctcatta cgcggttgct gctgctgttg
    64201 agatgattca tacaggaagt ttgattcacg atgatttgcc tgctatggat aacgatgatt
    64261 accgtcgcgg gcgactaact agccacaagc aatttaatga agcaactgct attttggcag
    64321 gagatagtct ttttttggac ccttttgctc taatcgcagg ggcagatttg ccggctgacc
    64381 tgctggtgca attgattcag cagttttcct tagcgtcagg aacctttggc atggtcggtg
    64441 gtcagctctt ggacatgaag ggtgagcatc agctgctgga tattcaggag ctatctgata
    64501 ttcatgccaa taaaacaggg aaattgttga cccttccttt tgtggctgcg ggtatcatag
    64561 ctgagcagtc agcagacgtt ttgtcttgtc tgtgggaggc tggtaggctt gttggacagg
    64621 cctttcagat aagagatgat atattagacc ttacggctag ctttgctgat cttggcaaga
    64681 caccgcaaaa ggaccttgct gctgcaaaat caacctatcc gagtctgctt ggtttagagc
    64741 gctcaagggc tattttggag gagtctttga gtcaagcgct agctattttt agcagactag
    64801 aaagggaaga aggctttgag tctcaggcta ttatcaaaag gatcgagggg ttgcgactaa
    64861 atggctaaag aaagagtaga tgtgctagcc tatagacagg gactttttga aacgcgagaa
    64921 caggccaagc gcggtgtgat ggctgggcta gttatatcag ctataagtgg cttacgcttt
    64981 gataagcctg gtgaaaagat tgatgagggg atcgaactaa ggctcaaggg tgagaagctt
    65041 aagtatgtca gccgaggggg tctcaagctg gaaaaagcct tgcaggtctt tgggatctct
    65101 gtgcaggata aggtgacaat tgatattggt gcttcaacag gtggctttac agatgttatg
    65161 ctacaggcag gagctaggct ggtttacgct gttgatgttg gaaccaatca attggtctgg
    65221 aagctcaggc aggatagtcg tgttcgaagc atggagcagt acaattttcg ctatgcaaag
    65281 ctagcagatt tttcagaagg tcagccagcc tttgccagca ttgatgtgtc ctttatttct
    65341 cttagcctga tactgccgac attgcactgt attttgcagg aaggggcaga ggctgttgct
    65401 ctgatcaagc cacagtttga agcagggcgc gagcagattg gcaaaaaagg gattgtcaag
    65461 gatagactga ttcatgaaaa agtgattaag caggtggcag atactgctct taattgcgga
    65521 tttatcgtta aggggcttga tttttcgcct atccaaggtg gtcatggcaa tattgaattt
    65581 ttggctcatt tagtcaaggg aaagggctcc aaggctattg atgatcagct catacagagc
    65641 gttgttagca gtgcacataa ggaatttaaa cagcatgaaa aagagtgaac gattagattt
    65701 aataaaaaaa atggttttgt ctcatgagat tgagactcag catgagctat taaagctcct
    65761 agctgattat gggctagagc taactcaggc cactatttca agagacatga atgaaattgg
    65821 cattgtcaaa attccatctg gaactgggcg ttatgtctat ggcttgtcac aggatagtgg
    65881 caagcgggtg gtgcaaaggc ctgcctctat caaaaaaacg attttggaaa tgtctgaaaa
    65941 aacagcgggc ttggagcagc atattcacct caacgttgtt ccaggcaata gcaagctaat
    66001 caaacgttat ttgatgacag acttttcagg tcaattgttt agcctgattg cagatgatga
    66061 tagtttgctg ttgattgcaa aatcagaagc agacgctgat catatccgtc aggaattgtc
    66121 cctttggatg cagggattgg tctaaaaaat agagagaagc cgatgttatt agaaatttcc
    66181 attaagaatt ttgctatcat agaggaaatc tctttaaact ttgaaaacgg tatgaccgta
    66241 ctgactgggg agacaggggc aggaaagtcc attatcattg atgcgatgaa catgctgctg
    66301 ggtgcgcgcg caagcactga ggtgattcga catggtgctg ataaggcaga gattgagggc
    66361 ttcttttcgg ttgatgctaa tcctcattta gccgctgtgc tggcagaatc agggattagc
    66421 atggaagagg agttgattct tcgtcgtgat atttttgcta acggtcgtag cgtcagccgt
    66481 atcaatggtc aaatggtcac tgtcagcacc ctaaaaaaac ttgggcagtt tttagtggat
    66541 attcatggtc agcatgatca ggaggaattg atgcgtccac agctgcacca gcatattttg
    66601 gatagttttg gagatgaggc ctttgaccag ctcaagcagt cctatcagca gatttttgat
    66661 cgctataagg ctttgcgaag gcaggctctt gagaagcaaa aaaatgaaaa agaacatcag
    66721 gcgcgccttg acctgctggc ctttcagata ggggaaattg aggcagcaga tttggttaga
    66781 ggagaagatg acctgcttaa ccaagaaagg cagcgattgc tcaatcacaa aaagattgct
    66841 gataccttaa ccagtgccta cctttccttg gataatgagg acttttccag tctctcacag
    66901 gtccgctcta gcatgaatga gttgctgtct attgaggacc ttgccccaga gtatcagctt
    66961 atatcagctg gtgtgtcaga ggcttattat attcttgagg aggtcacaaa gcaattatct
    67021 gataccatcg accagcttga ttttgatgca ggcagattgc aggacattga gctgcgttta
    67081 gacagcatta atagtctgac aagaaaatat ggcggtggtg tgaatgatgt tttggactac
    67141 tatgccaata ttaccaagga ataccagtta ttaagcggag atgaccgttc ctctgatgag
    67201 ctagaaaggg aattaaaggt ccttgagaag caactggtga tgactgcctc acagctaagt
    67261 gacaagcgtc atgccctggc tctagagcta gaagccgaca tcaaagctga gctgagagag
    67321 ctttatatgg aaaaggcgga ctttaaggtc cactttacaa ggtcaaagtt taatcgagaa
    67381 ggcaatgaaa gcttagaatt ttatatctca accaatccag gtgagggctt taagccgctg
    67441 gttaaggttg cttcaggtgg tgagctttcc cgcttgatgc ttgctatcaa ggctgccatt
    67501 tctaaaaaag aggacaagac gagtattgtc tttgacgagg tggatactgg agtttcagga
    67561 cgtgtggccc aggccattgc taaaaaaata tataaaattg gcagctatgg tcaggtatta
    67621 gcgatttcgc atttgccaca ggtgattgct attgcagata accagtattt tatttccaag
    67681 gaaagcaagg aggagtcgac agtgtctaag gctaagctgt tgacacagga ggagcggatc
    67741 gaggagattg cgaagatgat tgcaggagct gatgtcacag agacagcaag aaatcaagcg
    67801 cgtgaattgc taggtaagga ctgagtatca tagcaaaagc agaacagtag ctttagagca
    67861 agcttgcctg ctgcacttgt cgctacatgt tcagaatgag ccacctgaaa ggcaagcaag
    67921 aaggctagct cttatgcgta tgctatcaga agctaagtct ttttgtctct tgcattggcg
    67981 agtgattgat tgataatatt atgataaata gaaggactaa aagaatactg actgaggagg
    68041 taaaatgctg aaaaaaagaa tgggcttggc tagtctgcta gtgttgatga cctttgtgta
    68101 tcagtgctgt tcagttactg ctgagcagta ttccgatact gaggttgagg tgctgcagat
    68161 tagcgaggag aaaagccaga tcatggaaaa tcaagaggcg cttaaagacc tcaccacgtc
    68221 gtctgatcag ctaaagaagg aagctttaaa gcctaaagag gcagctacca acaagagcaa
    68281 gcaagaggct tcgacagttt atttagctga ggacgatcct gtaaccattg atagctctga
    68341 cgaggaaagc aatcaagata tcatagcgga ttctgttcct gatttggtta ttaaaggtga
    68401 tcaggtggat gtatctgagg ttatggtctc tgtaaaggag gattcatcga aagttgctaa
    68461 gcaaagaact gacgcagcgc agcggtacag tatagccaag catcaattga cccaaaagct
    68521 tgaggccttt aatgcggcaa cggaccaatt gctgaccatg attgctaaaa aatctgattt
    68581 gactggtcag tattatgtgg ttgggcattc gttgggagaa atgctggctg ctcaaaatga
    68641 gaaaaagctt gctgagcaat tagtcatgca acaaaagcac aaaaaaggct taggctcatc
    68701 agtcactatt ttagacgaat taggacgtgt gatttctgac attagtggtc ataaaggcat
    68761 gcttcctttt aatcgtaaga tcagctttaa ggtacatcaa gtcagatacg atcttccact
    68821 aactggtgat cgaacagtgc tacctgccca gctggctggc ttactgcttt tactaatagg
    68881 tcttatgctg cctaaagtag ctaacaagaa aagctaagat atggtcttgg cttttttatc
    68941 ttttaagagg gtgagttttt gacagatgtt ttagctaaca ccaagagcta gataccagct
    69001 ttgctttatt tttaaaggag tgataaaata aagagacgat aaatgaggtt agaaatggaa
    69061 cttaagatgg gaactattaa aattgttgca gattcatcaa tgacgattga accagagcta
    69121 atcaaatctc ttgatattac ggttgtaccg ctttctgtca tgattgatag caagctgtat
    69181 tctgataatg agctaaaaga ggaagggcaa tttctacagc tgatgagagc tagtaagtca
    69241 ttgccaaaaa ctagtcagcc accggtaggg ctttttgcag atatttatga gcgattggtc
    69301 aaggaggggg cgacagctat tgttgccatt cacctctcac cagctctttc aggaacaatt
    69361 gaggcatcac gtcagggagc tgaaattgca gcagcaccag ttacggtatt ggactcaggc
    69421 tttacagatc aggctttgaa gtttcaggtg gttgaagcgg ctagactggc tcaagctggc
    69481 gctagccttg aggaaatcct tgaggcggta gaggatatta aacgaaagac agagctttat
    69541 ataggggtat cagcacttga gcacttggtt aaggggggac gaatcggtcg tgtgacaggc
    69601 ttgcttagct ccttgctgaa tattcgtgtg gtcatggaaa tgaaaaatga taccctgcaa
    69661 acacttgtta aaggacgcgg caataagacc tttactaaat ggctggatag ctatctagca
    69721 gaaaatagcc agcgacagat agctgaggtg gccatttcct atgctggtca gagggatttt
    69781 gctgatagcc tgaagaagac aatcgctacg gtctttgatg ggccaattac tgttttggag
    69841 actggctcaa tcattcaaac acatactggc gagggcgctt ttgcggtgat ggttagatat
    69901 gaataagcga gggtttttgg gaggccttat cttctttttc agtgtttttg ccttatcatt
    69961 tgtgatatta gctgtcctta ttccaaagtc tgacccacag ctgaagaaaa gtgattttct
    70021 aaaaaataag aagataagcc tcaattatat tgctattgga gactccttga cagagggagt
    70081 gggtgatctc accaaccaag gaggctttgt gcccttattg tctggtgatc ttggagacta
    70141 ctttaatgct accgttaata ctgaaaatta cggtgtttcc ggtaatacca gccagcaaat
    70201 tttaacgaga atgactgaga acaaggagat cacagagcag ctcaaaaaag ctaatctcat
    70261 gacattaacg gttggtggca atgatgtctt ggctgttatt cgcaagaact tagctaatct
    70321 taaggtatca agctttaaaa agccagcaag gcaataccaa gagcgcttac gcaaaatcct
    70381 tgatttggcc agaaaggata atcaggatct gccgatcttt gttttaggta tctacaatcc
    70441 tttttatttg aattttcagg agctaacaga aatgcagacg gtcattaatg actggaacaa
    70501 aaaaacacaa gaggttgttg atgactatga ccatgtttac tttgttccaa ttaatgatct
    70561 attgtacaaa ggagtagatg gtaaagaggg cattgtccag tcaacaggag agcaaacaac
    70621 gattgtgaat gatgctttgt tttcagggga tcattttcac cccaataaca caggctacca
    70681 aatcatgtca gacgcagtaa tggagacaat aagaaagaat ggaaaagaaa ttaaacctta
    70741 attggtggaa atgggctttt ttgctattat tggcttttaa tgcagccttt ttagcagtta
    70801 ttggaagtcg tattatacaa ataagagagc ctaagtctga gctgatcaat caaaaagcag
    70861 caaagaatat taaaataggg accttaacaa ccactaaaga gcaattaaat gaggcagtcg
    70921 ttagctacct aaaggatttt cagacggaaa aaatgaccta taaggtgtat gccacctcct
    70981 cgaccattct ctttgaagga acctatcagc tcttaggata tgaggtgccg ttatacattt
    71041 attttcagcc tcatcgctta accaatggtg cgatacagct gcaggttctc tccttttctg
    71101 tggggaccct ttctttgccg gaaaaggacg ttttgcaata cttgaaatcc agctataagc
    71161 tgccaaaatt cgttgaagtc ttacctaagc aatcggctat tattatcaat ctacagcaat
    71221 tggaaaatga tgccaacatc tatttaaagg ctcaaaagat tgatcttgtc aaggatgata
    71281 ttcgatttga catctataag aaatgagtct aactaacgtt taatacttga cctgtggctg
    71341 ttttttagat atgataatat ctgttaaagc gttaagctta ctaattattt ggaggattgt
    71401 taaatggcta acaaacaaga tttaatcgca aaggttgcag aagcaactga gcttacaaag
    71461 aaagattcag cagcagcagt tgacgctgtc ttttctgcaa tcgaagcttt tcttgctgaa
    71521 ggtgaaaagg tacaattaat tggttttggt aactttgagg ttcgtgaacg cgctgctcgt
    71581 aaaggtcgca acccacaaac tggtgaagaa attgaaattg cagcttcaaa ggttccagca
    71641 ttcaaggctg gtaaagctct taaggacgct gtaaaataat aaatcaaaaa aagccctatc
    71701 tcattaagct gtttagcctg tgagataggg ctttttccat taaggaagga gtcttgtttc
    71761 aataagtaat cttgtgtgat cgtctgaaag attagcgcca ataatttcta atgtgcactg
    71821 tcttgggaac aagagttcca tttcataagg ataaaatgag tagggctgta caaaagcagc
    71881 ctggctgcct tgagggacct gaattcttaa ttccactgag cgatgtggca tagcagcatt
    71941 tttgatggct gtagtactca taaagccttg ctttgtataa tgagtgcctg gcttgatcgc
    72001 tgataggatc tgcggatcaa aggtcttatc atggtagtaa cgagcgagtt cctcttcaga
    72061 agtgcccaat tctgttaaga atgtttcata aacatagcga tagacgatga tattccaagg
    72121 gatggttagc ttatgagtag cactatcaag taaggctaca gactgctgca gctgggcatc
    72181 caactggctg gtatctccca tcacctgttc tagggctagg ttaatagggc tggcagaggc
    72241 gtatgtatac tgatacatca tctttttttc tgcttctgta aaggctgttt gagacctcca
    72301 gcgattggtg ataatgtatt tggtaacatc aggctcacta aatttataat aaggcttaaa
    72361 gctattccca tagggctcaa aaacaactgt ttgtccttca tcataagact gtgccttgat
    72421 ggttgaaggc tgaacgacaa gcaacgataa gaaaaatgta aacaagcata gtgtacgaat
    72481 agctatcctt tgataagata actttgcgtt atgatgttga tgagtcattt agcttttcct
    72541 cctttacagt agtgccaaga gtgtcatcac ctaatgatga tgtctgttgc taacaggatt
    72601 agccttagtt gaaatgatta caaacttcct taatgtaaca aacataataa aaataaatta
    72661 tttttttatt atatattagt taagctcaga tgacaagcta tttgattttt ttctgagata
    72721 atgttacaag ggatttctaa caccaatgac taactcagat gaagggcttt ttcttggagg
    72781 attgcctata gttacaatag taggcaagac tggcagtcgc catgatacct attccaataa
    72841 cagcaaaggt tgctagatga acagaggctg gtatacaggt catgatggta gttgccagtg
    72901 gcattaagag aatagcagtt gtgacgattg agctaaagac tcgtcctagc aatgcctcag
    72961 gaactttttt ttgaacgata gaaaagaagt gaatgttaaa gattgttaaa aagcattcaa
    73021 accataaatt cccaagggca atcacaatga ctggaagctt caagagagcc atagctgtta
    73081 ttagaagcat ccctaggcca ctaaggccta gggataggag taagctttgc tgattatttt
    73141 taaagagctt gttagccata aaagctccta agatagcccc taaagctccc atcgaaagaa
    73201 gactagcata gcttgattgg ctgcctagca gctgattcga aaaaggaatt aaataattga
    73261 aagcagcaat aaagaaattc acaagagaag caataatcaa caaagaaaaa atgtcattgt
    73321 catggtagat gaattgcagc ccctccttaa tatctgttaa aagctgaagc ctattgcctt
    73381 ggctgctctg tttagtgatg tgcctttctt tgtccttgat tgtatataga catagaaagg
    73441 acaatagaaa gctaatgcta tctagagcca aggctgtttt gatgccaaag caatccatca
    73501 ctaaaaaagc aagcattggt gaggaaatac tgatgatttg agatacgatt tctagctgag
    73561 cattgaaatg aacaagtctt tctgtttcaa ctagtgtgac cacataggct cgaaaagcag
    73621 ttccagagaa ggcatacgat attgctaaaa gagcattaac agtgataagc ccataaagca
    73681 tgatagtagg gttagctatc agggctaaaa gtccgcagct gatagctccg atagcatctg
    73741 tccacaataa caattgtcgt cgtttataac gatcagcaat ggcgccaccg ataggattta
    73801 agatgagtga aataaggcct tcagctagct gataataacc caaatattgt cggccagttg
    73861 ctccgagtcc agcaatcccg ctgctgttgc tgtagtcgta aacagtattg cctattttgt
    73921 taatagctcg acttgcgagc agctggtagt cgtttttgcg catgataaaa cctccaaaag
    73981 attatgtggt tttattataa atcagttttt tagggtctta tgtttttttg caaataaggc
    74041 tagaggaggc tacaaatctt tcaaaatcct tttggtaatt gtgcgctagg tgaggacaat
    74101 ccaggctctc aaaaatggaa atagcagtag tcatatcctt aatgccagac aaacactgtc
    74161 ctctttggta gtcctctaag ccctttaaaa ataaaaagat ggttttttca tatagcttgg
    74221 tttcattatt gagtagggct agtatctgct tttgataata gcgcgcatag tcaagctgat
    74281 gtcggtggat acaggtttcc caaatattga gaagggtgat ggtaaccaaa tgcttattgg
    74341 ttgaaatgct ttcgtagtag gtatgattgt ttagaatttc ctttcccatt ttatctaata
    74401 agggaatatc aataaaaaga tagagatttc caattaaaat cagctcatag atatgccagc
    74461 tttcagtcct aaaaaggtag tcagtgacct catcaagata agccttagga aaaggaatgc
    74521 taggattgca tttacagata aagccttgga gtagaatgct gtttaaatag taacgattgg
    74581 tatcaggatc agcttggtgc tttgccaatt cctgcttttg cagctgcttg aatccctcaa
    74641 tatcgcgtgc atattccagc ttgatcagct gcgacatgaa ttgaatttgc tctgtctgtt
    74701 tgaagttggc agctatgtcc ataaattcgc tgatttccac ttgcatgctg tctaaagctg
    74761 ttaaaaactt tgttactgat agatcagatt cgccgcgttc aaagcgggat aactgagaca
    74821 aggacacgtc tttactggca agctgctgta aggtgatatt tctgttttgt ctaatgctgc
    74881 gaaatgcttt tcccaactga tgattagtca tattttttcc tcctctaatg agtatatcat
    74941 gtaaggcttc tgttgctgta ttttcccgta tgtgcaaacc ttgaaacttg tctgctgccg
    75001 ccacaaaggc atgaaaacat ttacactttt tgatagctat ttttatcatt gatgtagtct
    75061 ttttcgcaac atttgtacgg gatcatcaga ttaaaattaa gaaactgatg atgtgacact
    75121 gtaaacatgc taaaaatatg ttgaacaatg cctgtagctg gaaaatgggt acatgtattt
    75181 tcttcatgcc tgcgtcgtga cctgctgcta ttaaagcttg cttgaaaggg aaaaagagct
    75241 tataatagca gtgagaacat taaaaatgaa agtagagata tgccaataat tgttatcctt
    75301 ggacttgcta tcttttcggt ggttaaggtc attatttttc tatgctttta taaagcattt
    75361 gagaaaaaac aactaaagaa gctagaacag gatcaaaaag aaaccaagca ggcgattgac
    75421 caagaggagt caaaaaaagc ctttcccttt taacataaag ctagaaaaag tctgagacct
    75481 ttcgtctcag acttttttta aggcttatat tgtaattgac cacgaaaatc gtctagtgtc
    75541 tggtagccct tttcagccat aatgtcttgt agctccttag tgatacgctt aaaaatagct
    75601 ggaccttcct ggtgcagtgc tgttccaatt tgtaccatag ctgcgccgca taggatatgc
    75661 tcaaaggcat cacgtcctgt tttgacaccg cctgtgccaa tgatctgaat agaagagtta
    75721 agccgttggt aaaaggcatg aacattagcc agggcagttg gcttgatgta atcaccacca
    75781 ataccaccaa agccgttttt aggcttgatg acgacctgct catcatcaat aaccaagcca
    75841 ttgccaatgg aattaacaca gttggcaaag gctaaggggt attgattgaa aatggctgcg
    75901 gcttggtcaa aatggacaat atcaaaataa ggaggtagct tgatgcctag aggcttggtg
    75961 taataggaaa agatcttttt taggagctga tctgtggctt caaagtcata ggccagctga
    76021 ggcttacctg ggacattagg gcacgacagg tttagctcga caagtccttg ataatcagag
    76081 gcctgaatag cttttaggat agtctcggtt tcttcagcag acatgcccac aacagataaa
    76141 aagtggtgct tgcttgcttg atccttttgc atttctgtga caatatctaa ataatactgg
    76201 tagccatgat taggaagtcc cattgaattg attgagccaa gtgctgtatc tgcatagcga
    76261 ggctcagggt tgccctgtcg aggggctaga gtacctgttt ttgtcacaaa ggacccagcc
    76321 tcagaggcct caatggctag cagctcttcc ttggtcatgc aatacactcc agcagcgttc
    76381 atcaggcaat tattaaaggc aaatgtagcg atttttgtgg cagtagaaac catgttttcc
    76441 tccattttta gacaaatttt ttctattcta tcactagggc atgagaatag caaggcattt
    76501 ttgcaaaata cttgcttgaa ggctttcttt tgtgaggttt tagcgttttt catgatatta
    76561 acaaaatgat tttcaataaa gagaggaata gactagcttt tttgacctat tttttgtaaa
    76621 ataggagttg taaaaaggca agaagccttt aaacttaata aggagatatt aactaatggt
    76681 aaaattggtt ttcgctcgtc atggtgagtc agaatggaac aaagcaaacc ttttcactgg
    76741 ttgggctgac gttgatttgt ccgaaaaggg aacacagcag gctattgatg ctggaaaatt
    76801 gatcaaggaa gctggtattg catttgatct tgcctttaca tctgtgctta agcgtgctat
    76861 caagacaact aatcttgcac ttgagtattc tgatcagctt tgggtacctg ttgaaaaatc
    76921 atggcgcttg aacgagcgtc actatggtgg cttgactggt aaaaacaagg cagaagcagc
    76981 tgagcaattt ggtgatgagc aggttcatat ctggcgccgt tcatacgatg tgttgcctcc
    77041 tgatatggct aaagatgatg agcattcagc acatactgat cgtcgttacg ctcatcttga
    77101 tcattctgtt attccagatg cagaaaacct gaaggtaaca ctagagcgtg cccttccttt
    77161 ctgggaagat aagattgcac cagccttagt tgatggtaaa aatgtttttg ttggagcaca
    77221 tggtaactct attcgtgccc ttgtcaaaca catcaagcaa ttatcagatg acgagattat
    77281 gaatgtggaa atcccgaact tcccaccgct tgtgtttgaa tttgatgaca agctaaatct
    77341 tactgctgag tactacctcg gtggtgaata atgctgtgag gccagaccta gctctggctt
    77401 tttttgttat gtgataaaaa aggcgtttcc aacagaaatg tgatatgata gttaaaaagt
    77461 ggtaaaagaa gggaatctta tgaaagtaaa ggaacgccga gaagctatta cagataggtt
    77521 aagccaagca caagaagcca tctcagcaac tagcttagcc aaggcattgg gagttagtcg
    77581 tcaggtgatt gtcggagaca ttgccttact tagggcgcag cagcttgaca ttatttcaac
    77641 accaaaggga tatatcctgt caaatgcttt gtttagtcat cactattctg ctagaattgt
    77701 ttgccagcat ggacctgagc agacaaggca ggagttggag ttgatattag cacatgatgg
    77761 cattgtgacc aatgtggagg tagagcaccc tatttatggc atgctgacag caccgcttaa
    77821 cattaaaagc tcagctgata tcaataactt tattgaaaag ctcggagcct ctaaggcaga
    77881 attattgtcg tctttgacag agggtctgca cactcacctt ttgtcctgcc ctgatcagga
    77941 ggcatttgaa gagatcaaga gagatctagc agctgcaggc attctctatg gtgaacaata
    78001 atctgatagc agctggcttc acagggattt agtcttggct tgatagccaa tgtccctctt
    78061 ttgtcgtagg tgatagggac cgcaggacag ctcctagatg ctgaggccaa agtcttgtgg
    78121 ctgggcctca aatgaggtta aaagggaagg aagctgctat ggttatggtg aaagggctag
    78181 atttaccctt acttttttgc taggataatc ttttatgctg ttaggccgca gggcttggtg
    78241 ctgcaatggc tgagatgtgt ctgtcttttg tcttagcttt tggtgcttga gaagggctgg
    78301 gattgagctt atgctgtggt tgttttttga tttgctaggt gtcttgacat ctgtcgcgtt
    78361 tttggttata ctaacgacta gtaaaaggag atattatgac caaaaaacca acacaactga
    78421 ttgcctactc ttctattttg gtggcctttg ccatcttgat tccgatgata atgcccatta
    78481 agcttattat tggcccggct tcctttaccc tagctagtca tctgcccttg tttttagcca
    78541 tatttatatc cattccggta gcgatcttgg tggggatagg aacaggtctg ggctttttgc
    78601 tagcaggatt tcctatgatt attgttatgc gagccttctc acacgtgctt tttgcagcta
    78661 ttgcggcttt tatgctcaaa aggcagccta aatggctgga aacaccgtta agaacctttg
    78721 tttttgggat tatagcaaat gtgattcatg gcctagcaga gtttttagtg gtttatctga
    78781 tgacagcaac agcagcaact gatctttctt atttttggtc aatgctaatg cttgttggct
    78841 ttgggtcttt gctgcatggt atggtggatt tttatctagc cttatttatc tggcgcttct
    78901 taaggcagaa gggtcatcta tcagtgacaa gctaggattt ctgtgagtat ttatgtttta
    78961 gtagccaagg ctgttacagg ctgaggctct tttttctgaa agcgcttgca tttttttgaa
    79021 aaaatgctat actaaagagt gcgtttgtaa atatactaac aaaaggagat gtcatgaaaa
    79081 caccagaaca gatattagcc gcgacgatta cgattggtga gcataaggtt gcaaagcctt
    79141 ttttggctaa ggctatttta ggctttattg gcggtgcgat gattagtttg ggctacttat
    79201 tgtatgttag gattgcagct agtgggctgg agacctttgg cgctttttct agtattttgg
    79261 gtgcttgtgc ctttccgatt gggctgatca ttattttgat ggctggcggt gaattgatca
    79321 caggcaacat gatggcggtg tcggcagcct tttttgcaaa aaagattaag gccaaggact
    79381 tgatggccaa ttggctggtg attacccttt ttaatatttt gggagccttg ttcgttgcct
    79441 ttgtttttgg tcattttctg ggtctgacag ctactggcag ctttaaagaa gaggtcattg
    79501 aggtggccca tgccaagctt gctgcaactc ctctacaggc tattgtttca ggaattggct
    79561 gtaactggtt tgttggcctg gcgctttggc tgtgctatgg cgctagtgat gcgacaggta
    79621 agctccttgg aacctggttt cctgtgatga cctttgttgc ccttggtttt cagcatagtg
    79681 tggccaatgc ctttgttatt ccggcggcta tttttgaggg tggcgccagc tggatcgatt
    79741 ttgcgactaa ttttgctctc gtttatgtgg gcaatgtcct tggcggtgct atctttgtta
    79801 gtctctttta ttacaaggct tatgatcact ctaaggaagc ctgattagtg ctgttatatt
    79861 tttagactgg gagaccttat tctcagtctt atttttatat tttgtgataa aataggaaac
    79921 gacgtttaaa aaggaggagt tgataagcat ctaatatggc atcatggata aaaaagaaaa
    79981 aagcaagcat tcctaggcga attcatctcc tttttttggt gattgttttt ttgtttgttg
    80041 ccctgatttt gagattggca caaatgcaga tttatgagaa ggatttttac aaggcaaagc
    80101 tgacagcgtc aaccgtttac aaagtaaaaa gctctatgcc aaggggaacc atttttgacc
    80161 gtaatgggaa ggttctagtt tctaatcgta tcaaggacgt ggtaacctat acgagaagtc
    80221 ccaaggctag tgctaaggac attaaggctt tggctcatca gctagctgct tatattagct
    80281 atcctgaggc taaagtgaca gtcagagcca aaaaggatta ttatttggca gatccagagg
    80341 cttatgctaa gacggttcaa gccttacccc aaaaggacaa ggtggatcgc tttggtaata
    80401 aattagtcga agcacagata tatcaaaatg cggcagcctc tcttaaggaa acagacttga
    80461 cctattcaga ccaagagcta aaggttattg ctatttttaa ccaaatgaat gcagcagctg
    80521 tttttagcac tgtaaagctc aaaacatcag ccttatctga gcaggatatt gccatcatta
    80581 tggccaataa gtcaaaatta ccaggtattt cagttgggac agactgggag cgtcaggtgg
    80641 aggagacaag ccttgctgct attattggaa gggtctctag tgaggaagcc ggtcttccaa
    80701 aggaagaagc aaaggcttat cttaaaaagg gctattcgct taatgatcgt gttggaacct
    80761 cttatctgga aaagcaatac gaggaggtcc ttcaaggaaa gcatgaaatc agagaaatca
    80821 aaacgagcag atctggtgag gttatttcag ataaaatagt cgaaaagggt cagatggggc
    80881 ggaacctgaa gttgagcgtg ccacttgatt ttcaacaggg cgttgagcag atcttgaatc
    80941 agcacttcca gacagagctc aaaaatggtc aggctgctta ctcagaaggg atctatgctg
    81001 tggcgcttaa ccctaatacg ggagcgattt tagcgatggc aggtctatca cacaatccca
    81061 aaaccggtga gcttcaaaag gacgctttag ggactattac tgatgtgttt acacctgggt
    81121 ctgttgtcaa gggggcgacc ttggctgccg gctggcaggc tggagtgatt caggggaatc
    81181 aggtcttgat tgatcagccg attcaatttg gtggctccca gccgattaat tcttggttta
    81241 ccagcggtca gcaccctatt actgctagtc aggcgctgga atattcatca aatacttaca
    81301 tggttcaggt tgccttaaga atgatggggc aggattacgt gactggtatg accttggcca
    81361 atactggtat gaaggaaacc atgaaaaaat tgcgggcagc ctatgccgaa tttggcatgg
    81421 gagtggcaac tggcgttgat ttgcctggcg aatccagtgg ctacctcata gatcaatata
    81481 atactgcaaa tgttttgaca gaggcctttg gtcagtttga taactataca accatgcaac
    81541 tggcccaata tgtctcaact attgctaatg gcggcagtcg ccttgcgcct cacattgtag
    81601 aaggcattta tcaggataat gaccagtcag gaccaggtaa gctaagtaag gctattgaga
    81661 ctaccttgtt aaacaaggtg cacttagctg ctgatagttt agcgattatt caggacggtt
    81721 tttatcaggt ggtcaatagc ggtagtggct atgctacagg tagggctctt gcaggaggtc
    81781 ctgttaccat tagtgctaaa accggtaccg cagaaaccta tgctaaggat aaaaatggtc
    81841 aggctttatc tacctttaac ttgaatgttg ttgcctatgg tccgagtgct agtcctcaaa
    81901 ttgctgttgc tgtcatgtat cctcatgcga cagactctct agccaaggca catcaatacg
    81961 tggctaagga tatcattaat ttgtacatga agatgtataa aaaccaataa aggagaaacg
    82021 agtgctttac cctataccaa tcgcaaaatt aattgaaagc tattctaaat taccagggat
    82081 tggtgttaaa acagcgacaa gattggcttt ttacaccatt ggaatgtctg atgaggatgt
    82141 gaatgatttt gccaaaaatt tattagcagc taagcgagaa ttaacctatt gctctatctg
    82201 tggcaatttg acagatgatg atccctgcca tatttgcaca gatagcagtc gggataaaga
    82261 gatcatttta gttgttgagg attccaagga cgtttctgcc atggaaaaaa ttcaagaata
    82321 tcatggctat taccatgtgc tgcatggctt gatttctccc atgaatgggg ttggcccaga
    82381 tgacatcaat ctaaagagcc taatcacgcg tttgatggct ggagaggcaa cagaggtcat
    82441 tgttgcaacg aatgccacag cagatggaga ggcgactgcg atgtacatct cacgtctcct
    82501 aaagcctgct ggtatcaagg tgacgcgatt ggctagaggc ttggcagtag gatcagacat
    82561 tgaatatgct gatgaggtaa ccctgctgcg agcgattgaa aatcggacag aattatagct
    82621 tagcccattt tcagctctct gtcattagcc cttatgccat gtgataaggc cataaaggaa
    82681 ggcagatttt gtcagagtct tttgaaaagc aagctcgttt ttgttataat aagtggtagt
    82741 ctaattcaga tagggaaggt tatcaatgtc taaacaaacc ttaattttat tatacggagg
    82801 gcgttcggca gagcgtgaag tatcagtgct ttcagctgag agcgtgatga gagcagttga
    82861 ttacaccaaa ttttttgtta aaacctattt tatcagccag acaggtcagt ttatcaagac
    82921 acaggaattc tctagtcggc cgaccttaac agaaaggctg atgaccaacg acactattag
    82981 gctagagcag cagataaggc ctagtgatat ctacgaggag ggggctgttg tttttccagt
    83041 cttgcatggc cctatgggag aggacggttc tattcaaggc tttttagagg tgctaaaaat
    83101 gccttatgtg ggaactaata tcctctcatc aagtgttgca atggataaga ttaccaccaa
    83161 aagggtccta gagtcagctg gtatcccaca ggttgcttat accgtttata ttgaggggca
    83221 ggatttagac aggtgtctgg cagagactga ggcagtctta agctaccctg tgtttgttaa
    83281 gccggccaat atgggctcat ctgttggtat ttctaaggca gaatcagagg aggagttgcg
    83341 tgcagctatc ctgttggcct tgacgtatga cagtcgtatc ctgattgagc aaggggtttt
    83401 ggcaagagag attgaggttg gactgcttgg taataccgat gtcaaatcaa cccttccagg
    83461 agaggtagtc aagaatgttg acttttatga ttatcaggcc aaatacattg ataatgagat
    83521 cacaatggct attccggcag ctattgacga atcagctatg acaagcatgc gtacctacgc
    83581 agaaacagcc tttaaggcta ttggtgcttg tggcctgtcg cgttgtgatt tcttccttgg
    83641 tcaggacggt cagatctacc tcaatgaatt aaataccatg cctggcttta cgcagtggtc
    83701 catgtatccc ttgctctggg agcatatggg actgagctat gctgagctta ttgaggagct
    83761 agtcagatta gcacaggaaa tgtttgaaaa gcgtgaaggg catttaatat aagagacaaa
    83821 ggacggaagg agatatagca atcctctgtc ctttcgtttg gcctgattgg tagcgttttt
    83881 tggtcagaag cctttaaagc cctatcgtct acggttggct gtgccagctt tagcctgtct
    83941 atgaaggatc agcctgtagg cataaagtga aatagaaaga atattcctaa tatgttatgc
    84001 tata
//
LOCUS       DARYNN010000002        63018 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.002, whole genome shotgun sequence.
ACCESSION   DARYNN010000002 DARYNN010000000
VERSION     DARYNN010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 63018)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 63018)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..63018
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.002"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            80..808
                     /locus_tag="TVB59_000081"
     CDS             80..808
                     /locus_tag="TVB59_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1009036.1"
                     /translation="MIKEQPLYLQIVDVLEVKIRNTMSANDKLLSERELSDLFGVSRI
                     TIRLALKELELRGLIYKQQGKGTYVSGIKEPATDLSSAYSFTEEMKKQGRKPQTVILS
                     FEKIKTTAYLSGMLDLDVDTDVFELERLRIADGKPLMFERTYIPERGFEAITIDLLEK
                     KPLYDVFAEDFQEAIRLADEEFYASIALDYEAKLLGIKKGDPVLHIMRKTYNEKNRLI
                     EFTFSIARADQFRYRIQHHPNKKI"
     gene            820..1995
                     /locus_tag="TVB59_000082"
     CDS             820..1995
                     /locus_tag="TVB59_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEL1009037.1"
                     /translation="MFTKTQAELELLGAAITTREIKQQPELWSEVFESFLKQKKDLLA
                     FFDRIIESANRNKVKIIFTGAGTSEYIGNTICHYLEMTGDRENYLYYSIASTDLVAAP
                     SQYLFEEDTVVLVSFARSGNSPESVAAVSLVNQLVSNPYHLVITCAKEGALAQNAKKD
                     KRSYLFLLPEASNDAGFAMTGSFSCMMLAALLIFDQAHSLEEKKCYLDQIVGMVAAII
                     QQEADLQKLVSLEFQRLVYLGSGALAGLTQEAQLKILELTAGKIATVYDSSMGFRHGP
                     KSFIDDQTLVIGFVSNDPYTRRYDLDVLEEIREDAIAVDTVALQQQGGEGFSGHCFGL
                     DSSMLLPDAYLAFPLVFIAQTLALLSSIKVNNLPDTPSATGTVNRVVQGVKIYHYFK"
     gene            2005..3000
                     /gene="lacD"
                     /locus_tag="TVB59_000083"
     CDS             2005..3000
                     /gene="lacD"
                     /locus_tag="TVB59_000083"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEL1009038.1"
                     /translation="MYHLSKAKYRLLEKVSRKGIISALAFDQRGVLKRMMAAHQDTEP
                     TPWQIEALKALVSEELTPYASSILLDPEYGLPATKVRDEKSGLLLAYEQTGYDTTTTS
                     RLPDCLVDWSVKRLKEAGADAVKFLLYYDVDGDERINQQKQAYIERIGSECQAEEIPF
                     FLELLTYDEAITDNQSVAFAKLKAHKVNEAMKVFSTERFGVDVLKVEVPVNMAYVEGF
                     AEGEVVYSKEEAMQAFRDQEAASHLPYIYLSAGVSASLFQETLVFAAEAGARFNGVLC
                     GRATWSGAVAVYMSEGEEAARQWLRTEGFENIDRLNQVLEKTASPWTTKLTLDEA"
     gene            complement(3042..3761)
                     /locus_tag="TVB59_000084"
     CDS             complement(3042..3761)
                     /locus_tag="TVB59_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1009039.1"
                     /translation="MTIKYPKYRLIKEELQNQILNGHYHTGDKFYTEAELIKRFHVSS
                     ITIIRALKELEKEGFIRRRQGLGTFITRTRKEQLVQFSYLGTFKDQKEEVTVLSVVKG
                     NDPYYLNLLKLHKTEFYYTISRTRTINQQPYLYQLSYIPHDYLLCPERDLADYQSLYK
                     RFFLDFHIQMRSQSFTQQTQLTDHMPKDVATFLNMIDNTPCVLQTKLTRSTDNGRILE
                     YTESYKHWQFFKYALSSSDYQ"
     gene            3901..5664
                     /locus_tag="TVB59_000085"
     CDS             3901..5664
                     /locus_tag="TVB59_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEL1009040.1"
                     /translation="MKQFCIKEQFYLDGKPFKILSGAIHYFRIAPDSWSRVLYQLKAL
                     GFNTVETYIPWNMHEPRKGQFTFEGIADVEAFLDLAQECGLYAIVRPSPYICAEWEFG
                     GLPAWLLTENCRLRSSDEVFLKHVSDYYDVLLPKLVKRQLDNGGNILMFQLENEYGSY
                     GEEKAYLRKLKELMLAKGISAPLFTSDGPWPATLASGSLIDDDVFVTGNFGSNASKQF
                     ASMQDFFQAHQKQWPLMCMEFWLGWFNRWNEPIIRRDSKEAVDAIMEAIELGSINLYM
                     FCGGTNFGFMNGSSARLQKDLPQITSYDYDALLDEAGNPTKKYTLLQERLKECYPQLS
                     FAEPMISSTMALESIKLSARVSLFKTIKNVSAIKKSFYPCNMEELDQPTGYLLYRTHL
                     ARHSKEERLRVIDARDRIQLFLDEKHVKTQYQEEIGQDILIHQEGETTQLDILVENMG
                     RVSYGYKLTAPSQQKGLGRGLMADLHFVGDWEHFPLDFQELDWIDFSAGWTDEVPGFY
                     AYDFDCQQPADTYLDLSQFGKGIALVNGVNLGRFWKVGPTLSLYIPKGLLKQGQNRLL
                     IFETEGQFSESIRLTKEPIYK"
     gene            5682..6167
                     /locus_tag="TVB59_000086"
     CDS             5682..6167
                     /locus_tag="TVB59_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1009041.1"
                     /translation="MTIVAARIDGRLIHGQVANLWTTKLNISRIMVVDNEVISNDLEK
                     TALKLATPSGVKLSILSVEKAANNILEGRYDSQRLLIVARKPDSFLELIQKGVAISEL
                     NVGNMSQTPETRPVTRSINVVDEDIEAFKAISAKGCHLIAQMVPNDAPADFMPLLDKV
                     D"
     gene            6213..7094
                     /locus_tag="TVB59_000087"
     CDS             6213..7094
                     /locus_tag="TVB59_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEL1009042.1"
                     /translation="MIQWWQILLLTLYSAYQILDELTIVSSAGSPVFAGFISGIIMGD
                     VQTGLWIGGSLQLMVLGVGTFGGASRIDATSGAVIATAFSVAQGIEPELAISTIAVPV
                     AALLVYTDILGRFSTTFFAHRIDRHVENFNYRGIERDYLMGAVPWALSRALPVFLAVS
                     LGGGAVDTVVKFIDHYEWLANGLTLAGKMLPGLGFAILLHYLPVKRNLHYLALGFGLT
                     AMLTTIYTNLQVAGGALAGVAKDFNAAPFKGLPMIGIAIIGLSLATLHYKNGQQAPVA
                     EQKPGVSESGEIEDDEI"
     gene            7081..7899
                     /locus_tag="TVB59_000088"
     CDS             7081..7899
                     /locus_tag="TVB59_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HEL1009043.1"
                     /translation="MTKSNYKLTKQDFNQINKRSLFTFQWGWNYERMQGSSYLYMILP
                     QLRKIYGDGTPELKEMMKTHTQFFNTSNFFHTIITGIDLALEENEGLASKDAVNGIKT
                     GLMGPFAPIGDSVFGSLVPAIMGSIAAGLAKEGVWSGITGVLMWVCTQMIINVFRWKQ
                     LEIAYKEGTKLVTTMRDKLTAVVDAASVMGVFMVGALIATMINFQFTAAPKIGEKVIN
                     IQDLIDTIFPRLVPALFTGGIFWLLGRKGMSPTKAIVVIILFALVMSYFNILGV"
     gene            7903..8307
                     /locus_tag="TVB59_000089"
     CDS             7903..8307
                     /locus_tag="TVB59_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HEL1009044.1"
                     /translation="MAQTLILISHGAFCRELKQSTEMIMGPQDNILTAELQPNEGADD
                     FKEKLLRLIAGLDDVLVFADLMGGTPCNVASRLLMEGHQFELYAGMNMPMVIGFINAC
                     LIGEAFDFKAFACDNIHHVNTIISALADDDDD"
     gene            complement(8411..8671)
                     /locus_tag="TVB59_000090"
     CDS             complement(8411..8671)
                     /locus_tag="TVB59_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEL1009045.1"
                     /translation="MRKDIHPDYRPVVFLDTTTGYKFLSGSTKTSKETIEFEGETYPL
                     VRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAK"
     gene            complement(8796..9728)
                     /locus_tag="TVB59_000091"
     CDS             complement(8796..9728)
                     /locus_tag="TVB59_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEL1009046.1"
                     /translation="MTTFQTILEHIKHYQTIIIHRHQNPDPDALGSQAGLKEIIRHNF
                     PDKKVLITGFDEPSLAWISLMDQVSDDDYKEALVIVTDTANRPRIDDERYTMGACLIK
                     IDHHPNDDVYGDLSYVDTKTSSASEIIAEFAFSQGLALTDEAARLLYTGIVGDTGRFL
                     YASTSSKTLAIASQLRNYAFDFAAISRQMDSFPLKIAKLQGYVFEQLDIDDSGAARLL
                     LSQEVLNSFGISLAESSAIVSAPGKIDVVQAWVIFVELPDGQYRVRMRSKEKVINGIA
                     KRHQGGGHPLASGATSSGLEENEQIYQELIDLLT"
     gene            complement(9738..10166)
                     /locus_tag="TVB59_000092"
     CDS             complement(9738..10166)
                     /locus_tag="TVB59_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1009047.1"
                     /translation="MWVVKAFDQLTKDELFAIYKERVAVFVVEQQCPYPDIDDLDQKA
                     IHLFKQVDSELRAYCRLIPTDNSIKLGRVLVAQNARRTGLGRDLVHQALAYCQQHFPK
                     LPVYAQAQAYLEPFYSSFGFKAVSEIYLEDNIPHIDMIKN"
     gene            10424..11449
                     /locus_tag="TVB59_000093"
     CDS             10424..11449
                     /locus_tag="TVB59_000093"
                     /EC_number="3.5.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HEL1009048.1"
                     /translation="METKDLKKLAKAELHCHLDGSLSLDTIRQLAALAQVDVPQDDSE
                     LKQLVTAPETCESLMDYLKTFDVIRPLLQTPQALTLAAYDVVKQAALENVIYIEIRFA
                     PELSMDQGLTATQVVEAVLKGLEQGQKEFGIVAKAIVCGMRQSSLDISREIFANVLEW
                     ANKGLVGFDFAGNELDFPPAVLADLIKETQAYGLPFTLHAGECGCPNYIVDAIDLGIK
                     RLGHVTAIHNQKDLLAKFIANDVTAELCFTSNLQTKAARTVEDFPYMQLRQAGAKLSI
                     NTDNRTVSDTNLTKEYELFVKHFETSVTDFLEHNRDAIKASFASPAEKEALLDRLEKA
                     YQSYIKK"
     gene            11510..11956
                     /locus_tag="TVB59_000094"
     CDS             11510..11956
                     /locus_tag="TVB59_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEL1009049.1"
                     /translation="MALAKIVYASMTGNTEEIADIVANKLQELGHDVEVDECTTVDAS
                     ELEAADMAIVATYTYGDGDLPDEIVDFYEDLQDLDLSGKIYGVVGSGDTFYDYFCKSV
                     DDFDEQLAATGATKGADSVKVDLAAEEEDIARLESFAEQMSQALEA"
     gene            12285..12578
                     /locus_tag="TVB59_000095"
     CDS             12285..12578
                     /locus_tag="TVB59_000095"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEL1009050.1"
                     /translation="MGLETIRQDINAVDRQLIALLEKRMVLADQVAAYKQVHDVPVLD
                     QEREAEVLRSVSQQIRHKAFEPAILELFKTIMAVSRRYQAEQIAVGSNDDEAY"
     gene            12559..13790
                     /locus_tag="TVB59_000096"
                     /pseudo
     CDS             12559..13790
                     /locus_tag="TVB59_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622696.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
     gene            13936..14283
                     /gene="rplS"
                     /locus_tag="TVB59_000097"
     CDS             13936..14283
                     /gene="rplS"
                     /locus_tag="TVB59_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEL1009051.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGSRERIQIFE
                     GVVISRKSQGISEMYTVRKISSGIGVERTFPIHTPRVEKIEVVRHGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            14798..14869
                     /locus_tag="TVB59_000098"
     tRNA            14798..14869
                     /locus_tag="TVB59_000098"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:14831..14833,aa:Arg,seq:cct)
     gene            complement(14993..15796)
                     /locus_tag="TVB59_000099"
     CDS             complement(14993..15796)
                     /locus_tag="TVB59_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL1009052.1"
                     /translation="MSKSRRRNWKSLTIVLLTILTIFTANSVQSARKLRTFPDTTEIS
                     LGTKATEIPGILPFTGKYQIALGDLDHLQRATYAHIQLKDQDEPTLKRKALRFNPPGW
                     HNYQVINSRGKKTWLMDRGHLVGYQFSGLNDEPKNLVTMTKYLNTGFSDKNPLGMLYY
                     ENRLDNWLAIHPNFWLDYKVTPIYQNDELVPRQVVLQYVGIDQNGELLQIKLGGNKES
                     VDHYGITSVVLDNVSPLAALDYRTGMLLDENQHTEEGNNLATEELDEAA"
     gene            16424..16639
                     /locus_tag="TVB59_000100"
     CDS             16424..16639
                     /locus_tag="TVB59_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1009053.1"
                     /translation="MAYRLRNRLKELRARDGINQTQMAALAGVSRQTISLIERNEYTP
                     SIIIAMKIAKVFNEPIEQVFSLVEGER"
     gene            16636..17412
                     /locus_tag="TVB59_000101"
     CDS             16636..17412
                     /locus_tag="TVB59_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEL1009054.1"
                     /translation="MKAFMTEKDSTLVRILKSLLLGSGIGLVLGGLVGFGLARFNILE
                     NGFPISEEDTITGIKWGMRPLVIVLMLLSIYDIYQVVKEYARYVKLSDDETEELYRYI
                     NLKHAYALGFSAMAMVLNIVVFSLGYRVPIANNASYLGLTFPIYEALMLVVISVLHAY
                     ILKVYTRIRGVKMTLAPTLKELKQNILQQDEAELQANYQMSFEVVMGLSGFILPGIYV
                     ILLLLSMIFQRVELTGLIITASIHLYILVKSFKSAHDFYR"
     gene            complement(17481..18737)
                     /locus_tag="TVB59_000102"
     CDS             complement(17481..18737)
                     /locus_tag="TVB59_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEL1009055.1"
                     /translation="MITRLITFLTWTGQLVVAGVIAGVVAYVLTQAIHFIQAISFGYQ
                     SGSFSTMIATVAPERRFLSLLLAGAIAGLGWQLLAKKAKPIQPIQQTLSQQKDFSPWT
                     QFCHGWLQLITVSMGAPVGREGASREVAVALTAACNKAINASAAEQGLLLACASGAAL
                     GAVYQAPLATIVFIMEAIVKKCSVKHIYAAAITAFTAVQSVLVLSGHQDIQYLILPQA
                     WQLTTVLWAIIASPILAFLAFCYQQLLQNAPKAKPKSRWFIPRVLGAFGFSACLSLYF
                     PEILGNGKAGLLLLLHHDVSLSYTASLLLSKAAAVYAVFASGAKGGKIAPSMMLGGAS
                     GLLLASLSNQLGYLSVPLPLAIVIGATLFLGIINQIPLTAPLFLIEITGQPLISLVPL
                     AIVGLTSYLSQQLFQKSLFFNKHKKL"
     gene            complement(18823..19782)
                     /gene="nrdF"
                     /locus_tag="TVB59_000103"
     CDS             complement(18823..19782)
                     /gene="nrdF"
                     /locus_tag="TVB59_000103"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEL1009056.1"
                     /translation="MTTYYEAINWNEIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RRLSAVEKDLVGKVFGGLTLLDTMQSESGVEAIRKDVRTPHEEAVLNNIQFMESVHAK
                     SYSSIFSTLNTKKEIEDIFEWTNNNVFLQNKAKIINDIYENGSALQKKVASTYLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELSESEQESLR
                     DWMYDLLYQLYENEEQYTKTLYDEVGWTEEVMTFLRYNANKALMNLGQDPLFPDTAND
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGTVEAMTDDDYNYGL"
     gene            complement(19927..22086)
                     /gene="nrdE"
                     /locus_tag="TVB59_000104"
     CDS             complement(19927..22086)
                     /gene="nrdE"
                     /locus_tag="TVB59_000104"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEL1009057.1"
                     /translation="MSLKDLGDISYFRLNNEINRPVDGSIPLHKDKEALEAFFTENVI
                     PNTMSFSSINEKIAYLVDNDYIESAFIQNYSPEFISHLAKSIQAEGFRFKSFMAAYKF
                     YQQYALKTNDGNFYLESIEDRVMFNALYFADGDETLAKDLAIEMINQRYQPATPSFLN
                     AGRSRRGELVSCFLLQVTDDMNAIGRSINSALQLSRIGGGVGISLSNLREAGAPIKGY
                     AGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLSVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGITVPDKFYELARHNADMYLFSPYSVEREYGLPFNYIDITSMYDELVANPNI
                     TKTKIKARDLETEISKLQQESGYPYVINIDTANRSNPIDGKIIMSNLCSEILQVQTPS
                     LINDAQEFVKMGTDISCNLGSTNILNMMTSPDFGRSIRAMTRALTFVTDSSNIEAVPT
                     VKNGNSQAHTFGLGAMGLHSYLAQHHIEYGSPESIEFTDIYFMLMNYWTLVESNQIAR
                     ERQTTFVGFEKSTYASGAYFDQYITGECVPKSELVKSLFKDHFIPQAADWKALRQAIM
                     TDGLYHQNRLAVAPNGSISYINDCSASIHPITQRIEERQEKKIGKIYYPANGLSTDTI
                     PYYTSAYDMDMRKVIDVYAAATKHVDQGLSLTLFLRSELPKELYEWKTESKQTTRDLS
                     ILRHYAFNKGIKSIYYIRTFTDDGEEVGANQCESCVI"
     gene            complement(22107..22325)
                     /gene="nrdH"
                     /locus_tag="TVB59_000105"
     CDS             complement(22107..22325)
                     /gene="nrdH"
                     /locus_tag="TVB59_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEL1009058.1"
                     /translation="MITVYSKHNCMQCKMTKKFLEQHGAAFQEINIDEHPEKVDYVKS
                     LGFTAAPVIETEQIVFSGFQPAKLKDII"
     gene            22747..23010
                     /locus_tag="TVB59_000106"
     CDS             22747..23010
                     /locus_tag="TVB59_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEL1009059.1"
                     /translation="MASKDFHIVAETGIHARPATLLIQTASKFASDITLDYKGKAVNL
                     KSIMGVMSLGVGQGADVTITAEGADADDAIAAIEETMTKEGLA"
     gene            23015..24748
                     /gene="ptsP"
                     /locus_tag="TVB59_000107"
     CDS             23015..24748
                     /gene="ptsP"
                     /locus_tag="TVB59_000107"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEL1009060.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DVALQASQDELSVIREKAVESLGEEAAAVFDAHLMVLADPEMISQIKETIRAKQTNAE
                     TGLKEVTDMFITIFEGMEDNPYMQERAADIRDVAKRVLAHLLGVKLPNPATIDEEAIV
                     IAHDLTPSDTAQLNKQFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNDITKRVKDGD
                     LIAVNGITGEVIIDPSEEQILAFKEAGEAYAKQKAEWALLKDAQTVTADGKYFELAAN
                     IGTPKDVEGVNDNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDLPKEMNPFLGFRALRISISETGNAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKVVFEEEKASLLSEGVAVADDIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDSAKMAEYAHRALTECSTAEEV
                     LELAKEYITEA"
     gene            24950..26377
                     /locus_tag="TVB59_000108"
     CDS             24950..26377
                     /locus_tag="TVB59_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019322885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEL1009061.1"
                     /translation="MAKQYKNLVNGEWKLSENEIKIYAPATGEELGSVPAMSREEVDQ
                     VYASARAALADWRALSYVERTAYLHKAADILVRDAEKIGAVLSKEVAKGYKAAVSEVI
                     RTAEIINYAAEEGLRMEGEVLEGGSFEAASKKKIAIVRREPVGLVLAISPFNYPINLA
                     GSKIAPALIAGNVVVLKPPTQGSISGLLLAEVFAEAGLPAGVFNTITGRGSVIGDYIV
                     EHEAVNFINFTGSTPIGERIGKLAGMRPIMLELGGKDSAIVLEDADIALAAKNIVAGA
                     FGYSGQRCTAVKRVLVMESVADQLVAEIKGLVEKLLIGMPEDNADITPLIDTKAADFV
                     EGLVNDAADKGAQALTEIKRDGNLICPILFDRVTTDMRLAWEEPFGPVLPVIRVSSVE
                     EAISISNQSEYGLQASIFTTNFPQAFAIAEKLEVGTVHINNKTQRGTDNFPFLGAKKS
                     GAGVQGVKYSIEAMTSLKSVVFDIQ"
     gene            27030..28244
                     /locus_tag="TVB59_000109"
     CDS             27030..28244
                     /locus_tag="TVB59_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEL1009062.1"
                     /translation="MLPKRKLIDQRLDYAIIFPVFCLLIFGLVSVYVAASHDFPQSLA
                     TVMLQQVLWILLGAVIAFTLMFFSTEILWKLTPVFYLLGVLLMVLPLIFFSPRLVAAT
                     GAKNWITIGSTTLFQPSEFMKISYILAMSWLTVWFKRKQERSRFLDDWKLLGLYLVLT
                     LPVMVLLALQKDLGTAMVFLAILAGIILISGISWWLILPALVLVFLLVSAFFFVFLLP
                     EGKEFLLKMGMDTYQLNRISAWLTPFDFSDTIAYQQTQSMISIGSGGFFGKGFNQLEL
                     SVPVRESDMIFTVIAENFGFLGAASLLILYLILIYRMLRVTFASNNLFYTYISTGFIM
                     MILFHIFENIGAAVGLLPLTGIPLPFISQGGSSLISNLIGVGLILSMNYQHVLAHEKQ
                     SEHELSRSSRYV"
     gene            28340..28909
                     /locus_tag="TVB59_000110"
     CDS             28340..28909
                     /locus_tag="TVB59_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HEL1009063.1"
                     /translation="MKVMNYHDYIWDLGGTLLDNYEISTQAFIETLHFFKLSASHDAV
                     YQRLKKSTATAIQVFAPNEPQFLQYYKANEAKKLANPIWCLGAKDILKRIVASGSRNF
                     LISHRDHQVNDLLEQAGLLGYFTEVVTASNGFARKPNPESLLYLKEKYLISKGLVIGD
                     RRLDIEAGQAAGFDTLLVDGRKNLLEIVD"
     gene            28910..30862
                     /gene="gyrB"
                     /locus_tag="TVB59_000111"
     CDS             28910..30862
                     /gene="gyrB"
                     /locus_tag="TVB59_000111"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEL1009064.1"
                     /translation="MVEENKQLEDKAQEYDASQIQVLEGLEAVRMRPGMYIGSTAKEG
                     LHHLVWEIVDNSIDEALAGFASHIQVFIEADNSITVIDDGRGIPVDIQAKTGRPAVET
                     VFTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVRVYKNGHIHYQEFRRGAVV
                     DDLAIIGTTDVTGTTVHFTPDPEIFTETTEFDYQVLAKRIQELAFLNRGLKISITDKR
                     AGLEREEHFHYEGGIGSYVAFLNDKKDVIFDTPIYSDGELEGITVEVAMQYTTGYHET
                     VMSFANNIHTHEGGTHEQGFRTALTRVINDYAKKAKILKENEDNLTGEDVREGLTAVI
                     SVKHPNPQFEGQTKTKLGNSEVVKITNRLFSEALQRFLLENPQVARKIVEKGILASKA
                     RIAAKRAREVTRKKSGLEISNLPGKLADCSSNDASQNELFIVEGDSAGGSAKSGRNRE
                     FQAILPIRGKILNVEKATMDKILANEEIRSLFTAMGTGFGAEFDVSRARYQKLVIMTD
                     ADVDGAHIRTLLLTLIYRFMRPVLEAGYVYIAQPPIYGVKVGSEIKEYIQPGVNQEEE
                     LKAALERHSTGRSRPTIQRYKGLGEMDDHQLWETTMDPDNRLMARVTVDDAAEADRIF
                     DMLMGDRVEPRREFIEENAVYSTLDI"
     gene            31011..32735
                     /gene="ezrA"
                     /locus_tag="TVB59_000112"
     CDS             31011..32735
                     /gene="ezrA"
                     /locus_tag="TVB59_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEL1009065.1"
                     /translation="MSSGIILLIVAIVLLVIIAYLVGVIIRKRNDTLITSLEERKQAL
                     FGLPVNDEIEEVKSLHLIGQSQTSFREWNQKWVDLTLNTFTDIEKHIFEAEHLNDTFN
                     FIRAKHEINSVESQLNLVEEDITAIREALGILKEQEEKNSARVTHALDLYEKLQASVA
                     ENEDNFGSTMAEIEKQMKNIEAEFSQFVALNSSGDPVEAAEVLDKAEEHTIALGQITE
                     QIPAIVAKLEDDFPDQLDDLETGYRRLLEENYHFPEKNIEARFQEIRESIRANSSELV
                     TLDLDRARDENTHIQERIDSLYELFEREIAAYKVVAKNSKILPRYLAHAKHNNEQLKH
                     EIARLSRKYILSENEGLNIKAFDKDLKDIEDNVLEIAEAFDQQEKPFSELQLILDRSI
                     KTLASVESGQMDVFAAVKDIEKIESQARQHLEIYVTQLHMIKRYMEKRNLPGIPQDFL
                     STFFTTSSQLEALMDELSRGRINIEAVSRLSEVATAAIANLEELTYQVVQHATLTEQL
                     LQYSNRYRSFEAGVQNSFEHALKLFEVDNDYQASFDEISYALETVEPGVTERFVNSYE
                     KTRERIRF"
     gene            33107..33388
                     /locus_tag="TVB59_000113"
     CDS             33107..33388
                     /locus_tag="TVB59_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009066.1"
                     /translation="MKITKALCVAGAVAVLALAPISSSPAPTQTVFAATRGTEEYCHN
                     GWCSFLDEHGEWNTKREGESNSPLQRGSWWDWISYWSGYIWYSVYNWFR"
     gene            complement(33573..34028)
                     /locus_tag="TVB59_000114"
     CDS             complement(33573..34028)
                     /locus_tag="TVB59_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1694 domain-containing protein"
                     /protein_id="HEL1009067.1"
                     /translation="MDSLDTRLLKGASGENRFDPDQQRYYLGTYAERIVLALPLTEVD
                     HEKAKGYITAQLPHLKEAYFPLSFKLSSEFGSAYQMYYMKLAQQNALSATIVDEKGAV
                     SPFALIIHSDHAITKEETNLKAILDKPSDNKPAEQTKTKGKSLWQRLFH"
     gene            34259..35566
                     /gene="eno"
                     /locus_tag="TVB59_000115"
     CDS             34259..35566
                     /gene="eno"
                     /locus_tag="TVB59_000115"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEL1009068.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYLGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYTYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMIMPVGAPTFKEGLRWGAEVFHALKKILKARGLVTAVGDEGGFAPKFEGTEDG
                     VETILKAIEAAGYEAGENGIMIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQI
                     DYLEELVNKYPIITIEDGMDENDWEGWKALTERLGKRVQLVGDDFFVTNTEYLARGIK
                     EGAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAG
                     QIKTGSLSRTDRIAKYNQLLRIEDQLGEVAQYKGIKSFYNLKK"
     gene            complement(35702..35938)
                     /locus_tag="TVB59_000116"
                     /pseudo
     CDS             complement(35702..35938)
                     /locus_tag="TVB59_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400084.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            36147..36368
                     /locus_tag="TVB59_000117"
     CDS             36147..36368
                     /locus_tag="TVB59_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation repressor RelB"
                     /protein_id="HEL1009069.1"
                     /translation="MSTVTIRLNQEEEIFFKSYAQLTGQSLSSLFKKALERDIEDEYD
                     LKIYHQAYAEYKADPETISHADFKKELGL"
     gene            36370..36630
                     /locus_tag="TVB59_000118"
     CDS             36370..36630
                     /locus_tag="TVB59_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002998538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEL1009070.1"
                     /translation="MYRIEYSKKAQKQIKKVDKQIQRLLFAWIDKYLEGTDNPRANGK
                     GLTGNHANEWRYRIGDYRLICDIQDDKMVVLALEFGHRKDIY"
     gene            37283..37888
                     /locus_tag="TVB59_000119"
     CDS             37283..37888
                     /locus_tag="TVB59_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HEL1009071.1"
                     /translation="MGSTLIDESLAFNAFMKQWRISLARCGKQLTREELLSSINMLTA
                     AGICEFDLLWQRLAPKGCQRPKWSHQLERLFADTKPCLQVLSETYQLGIIANQAKGLK
                     ERLERFGISHYFALMISSSDVGLQKPDLALFRYALDQAGVLARDAVYIGDRVDNDIIP
                     AKALGMRAVRIHQGLAASSPDDRLYPSDVHISKLSDLLECF"
     gene            38356..41136
                     /locus_tag="TVB59_000120"
     CDS             38356..41136
                     /locus_tag="TVB59_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEL1009072.1"
                     /translation="MSNKKFFTYASLLALIAVPTVVEEVTAQPSAQLVYADELRLSPS
                     TDSSPVTKTDEADQPVAQSVSATEPVEALVIADKESALNPAVLADADGSQPIAVVRAG
                     QEGQPYTVTGKIISAVNGWGGHGFYIQDSQGSGLYIYPGSALGYVTGDVVQLTGTLTT
                     YKGELQLKTITKHHKINGELPTPIAEVTIPELEKASPSTLVKLSNVTVGDISSDKHET
                     SSFKVSDTAGNSVAVRLDNRTGVKTSDLLSKIGKGDVINLTAIHSTFDGKLQLKPFSL
                     EQFEVVKKVVREEEVTPLGRVVKIGQIQGASHTSPLLNQAVTVKEVVVTYLDDATHFY
                     VQDINGDNDKATSDGIRVFAQNAQVQAGDVLTISGTVEEFFGKGYDDRKQTDLTITQI
                     KASKVTKTGTAQVPAPLVLGKDRVAPANIIDNDGFSVFDPEEDAIDFWESLEGMLVAV
                     DNAKILGPMSHKEIYVLPGSSTRVLTNSGGILLPETGYNTDLIPVLFKKGKQTIKAGD
                     SYQGRLAGPVSYSYGNYKVFVDDSSRMPVLVDGQLKPEKTHIKKDLSKLSIASYNIEN
                     FSANPSSTKDEKVRRIAESFIYDLNAPDIIGLIEVQDNNGPTDDGTTDATQSAQRLID
                     AIKALGGPAYQYVDIAPENNADGGQPGSNIRTGFLYQPGRVSLSDKPRGGVNDAVKWV
                     NGELSLSVGRIDPTNPAWNSVRKSLAAEFIFQGHKVVVVANHLNSKRGDNSLYGRVQP
                     VTFKSEERRHVLARLLSQFTKEGASQQANIVMLGDFNDYEFTKTIKLIEEGDMANLVS
                     RHELSDRYSYFYRGNNQTLDNMLVSRNLLGRYEFDMVHVNSPFMEAHGRASDHDPLLL
                     QLSFGKDKPAAPSDQPKKTPAPAATTQASKAGRAQLLPKTGDKTALMVSILGLTAVFS
                     SFSLFRKCQERK"
     gene            complement(41558..41695)
                     /locus_tag="TVB59_000121"
     CDS             complement(41558..41695)
                     /locus_tag="TVB59_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003585727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL1009073.1"
                     /translation="MHQNPTERSVLLSTYEALQLMLAFGSFLLTLISLVVAIVILNNK
                     K"
     regulatory      41939..42057
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            42055..42561
                     /locus_tag="TVB59_000122"
     CDS             42055..42561
                     /locus_tag="TVB59_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEL1009074.1"
                     /translation="MTSFTVRDYVYIALVAALYVVLTITPPLNAISYGMYQFRVAEMM
                     NFLAFYHKKYIIAVTLGCMIANFYSFGLIDVLVGGGSTLIFVSLGVALFKQYQEEYLL
                     NGLLNKAFVYFSLFFATSMITVAIELYFFGAPFFLTWFTTAVGEFASLIIGSMIIDRL
                     SKRINLRQ"
     gene            42658..44616
                     /gene="ligA"
                     /locus_tag="TVB59_000123"
     CDS             42658..44616
                     /gene="ligA"
                     /locus_tag="TVB59_000123"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEL1009075.1"
                     /translation="MKKRIRELTDLLNQYRQEYYTNDAPSVSDSEYDKLYRELVELEQ
                     TYPAYILKDSPTQLVGSTILTGFQKYQHQYPLFSLQDAFSREELNAFDQRIKSAFPEA
                     EYLAELKIDGLSISLVYEAGVLKVGATRGDGTIGENITENIKNIKDIPKRLSQALDVT
                     IRGEAYMSRQAFKTINEERQENGEPEFANPRNAAAGTLRQLDTRIVAKRQLATFLYQE
                     VGLETADSQQKTLERLADLGFSVNSHYLLSSSMNDIWDFIQSIEASREELPYEIDGVV
                     VKVNQLAIQEELGFTVKAPRWAIAYKFPAEEKEAEIVSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRIGDTVVVYKAGDIIPAVLRVVEAKRRDQAPMPIP
                     TACPSCQSQLVHFEDEVALRCINPLCPSLVQRSLEHFASRQAMNIAGLGPAVVEKLYS
                     AGLVHDVADIYRLSLEDLLTLDGIKEKSAEKLLAAIEQSKANSAEKLLFGLGIRHIGA
                     KASRLILEAYGDLEALLAVTAEELAQIDGLGLVIGQSLVQYFQQEQAAQLLAELKSAG
                     VNLAYLGQRPDQQAALFGLTVVLTGKLEKLNRTQAMEKLEQLGAKVTGSVSKKTDLVV
                     AGSEAGSKLAKAQQLGIRIEDEDWLLNL"
     gene            44629..45651
                     /locus_tag="TVB59_000124"
     CDS             44629..45651
                     /locus_tag="TVB59_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEL1009076.1"
                     /translation="MKKQMRARLIYNPTSGQEIMKKNVAEVLDILEGFGYETSAFQTT
                     AAKHSALKEARRAAKAGFDLLIAAGGDGTINEVVNGIAPLEKRPKMAIIPAGTTNDFA
                     RALKVPRGNPVEAAKLIGKNQTIRMDIGRAKKDTYFINISAAGSLTELTYSVPSQLKT
                     MFGYLAYLAKGVELLPRVSNVPVKITHDHGIFEGEVSMIFAAITNSVGGFEKIAPDAK
                     LDDGMFTLILIKTANLFEIVHLLRLIIDGGKHVTDRRVEYIKTSKITIEPQSDKRMMI
                     NLDGEYGGDAPITLENLKNHITFFANTDLISDDALVLDQEELEIEEMVKKFAHEVEDL
                     EQGLEE"
     gene            45660..47960
                     /gene="pulA"
                     /locus_tag="TVB59_000125"
     CDS             45660..47960
                     /gene="pulA"
                     /locus_tag="TVB59_000125"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEL1009077.1"
                     /translation="MDNAVIVHYHSCKGHYFQLSLWQWRDGKLGKDAYFSRFDSFGAV
                     AYLTYPAPYFLSHAYVIVKDQFWQHQTVDFRIERDYGVPKTEVWLVDGDPTVYYSRQA
                     AVASRHDGRCDVHAFDMAVNSQAFDKRWGFSGWLGFRYQPEETSFRLWAPTAEKVELI
                     LYASTDERASVAKVLPMQRGQQYSPDHHAENTCGVWDISLRGDYNYHAYCYRVYYRRR
                     TFRDTRDPYAIATTANGKRSIVIAPEHLRPQGFSVKQGKEATWRLDNPNQAVIYEMHV
                     RDFSKSETSGVSLANRGKFKGLIETGTRNAFGDSTCFDYVKSLGITHIQLQPVFDHHQ
                     FFDENGDYAYNWGYDPENYNVPAASFTSNPHEPATRILELKEVIQAYHDAGINVIMDV
                     VYNHTYSSRESAFQLTVPDYYYRMNPNGSFQNGSGCGNETASEKEMYRKYMLDSILYW
                     TNEFNIDGFRFDLMGLHDIDTMNLIRQELDKIDPRILVFGEGWDMGVGLAAEQKAKKG
                     NASQMPGIGFINDDQRNAVKGAEVYGSLEKGFVSGAPTEGLVAKSILGSDELVSYCTP
                     SQVINYVEAHDNYNLNDLLWVLNPEDSKQDHVKRVQLASAMTILMQGIYFMQLGQEFL
                     RTKLYPTGQDKELTQADRERAMNSYNAPDNVNQVDWRQVSLERETVAIMKKLIYLKTK
                     TALFSYPSFEQIRQHVYIEHAGENTGFISFTVEDERKYRLIFSSFRNRLQSSANHVII
                     ETNDKRFQDSESMLDELTAMILDITQ"
     gene            48107..49986
                     /gene="glgB"
                     /locus_tag="TVB59_000126"
                     /pseudo
     CDS             48107..49986
                     /gene="glgB"
                     /locus_tag="TVB59_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004234331.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
     gene            50053..51192
                     /locus_tag="TVB59_000127"
     CDS             50053..51192
                     /locus_tag="TVB59_000127"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019785022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HEL1009078.1"
                     /translation="MKNGMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVITQYQPLALNNHIGNGSSWGLDGINSGATILQPYSATEGNRWFQGT
                     SHAIYQNIDYIDSINPEYVLILSGDHIYKMDYDDMLQTHKANMASLTVAVIDVPLKEA
                     SRFGIMNTDTNDRIVEFEEKPANPKSTKASMGIYIFNWQRLRTMLVDAEKNNIDMSDF
                     GQHVIPSYLESGERVYTYNFKGYWKDVGTIESLWEANMEYIGEENALDSRDRSWKIYS
                     KNHIAPPNFITEDAEVKDSLVVDGSFISGKVNHSILSTNVQVRKGAEVKDSFIMSDVI
                     IGEGARITRAIIGEGAVIGDHVIIDGSKDVQVVGYNEVVGVPNED"
     gene            51182..52315
                     /gene="glgD"
                     /locus_tag="TVB59_000128"
     CDS             51182..52315
                     /gene="glgD"
                     /locus_tag="TVB59_000128"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEL1009079.1"
                     /translation="MKIDKYSAILGSSIGFAEMKGLTDTRPLANLPFDGKYRLIDFQL
                     SNLANAGVRSIYGIFRGQNIRSVFDHIRSGREWGLNSLLSHYFLGFYNTKEDSKEADK
                     DYYQQILTYLKRSGSDQTIYMSCDILCNIELGQVIHLHNANHRNITVVYKKMPTKAIS
                     KANDILDIDETDTVVDRRSLSEGQEVEKMSAGIYIVNTPWLIEQMEKEAEKENPQKLR
                     FLLRDLIVSEGALGFEYTGYLANIHSVKSYFDANMDMLDPHKFYSLLYANQKVYTRVK
                     NEESTYFDAASEVNNAQFASGSIVKGYVEHSIVSRNCRITSQARVTNSILLPKAVIGE
                     GAVIDYAIIDKSVRVAPGVTIRGSAEEPIVVAKGTEVVEDMIK"
     gene            52312..53742
                     /gene="glgA"
                     /locus_tag="TVB59_000129"
     CDS             52312..53742
                     /gene="glgA"
                     /locus_tag="TVB59_000129"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEL1009080.1"
                     /translation="MKIMFVAAEGAPFAKTGGLGDVIGALPKSLVKNGHEVSVILPYY
                     DVVDQAFGQQVEDVLYFYTQVGWRRQYVGIKKLVKDKVTFYFIDNQGYFFRGRIYGDW
                     DDGERFAYFQLAAIEAMEKIGVIPDILHVHDYHTAMIPFLLKEKYHWIQAYQAIRTVF
                     TIHNIAFQGQFDPGMLGDLFDVGIERYEDGTLRWHDCLNWMKAAVLYADRVTTVSPSY
                     AHEIQTPAFGQGLDQVMRMEAGKLSGIVNGIDTDLFNPARDPHLPASFSAEDLSGKAA
                     TKQALQERLGLPVRADVPLIGMVSRLTDQKGFQLVLEELPHILQQDVQLVLLGTGDPD
                     YEAAFSWFAKAYPEKLSANITFDLPLAQQIYGACDLFLMPSAFEPCGLSQMMAMRYGA
                     IPIVHEIGGLKDTVASYNAYEKTGTGFGFDQFSGFWLTQTLLFALDIYHNHKEDWQTI
                     QQHAMTKDFSWDTASLAYLDLYKSLL"
     gene            53761..56157
                     /locus_tag="TVB59_000130"
     CDS             53761..56157
                     /locus_tag="TVB59_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004234325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HEL1009081.1"
                     /translation="MHVTKEQFIRDFKDTLHEEQLIKVPAATAAELFTSLAKLIRKYY
                     TDTWIERNRSLTEQQQKIAYYFSIEFLPGRMLETNLLNLGILDTVKEAFADLGIDFQA
                     VKHAEHDMALGNGGLGRLAAAFMDSLATTGYPGFGNGLRYRYGLFKQRIVNGYQVELP
                     DSWFGSIGNVWEIRKDHDIVDVKLFGNVYLKANQDGKLAPIYEGAQVLRAVPYDVPQI
                     GFENDVINNLRLWDVEIPEEHELDYPTIESRRAVKDITAILYPDDSSYEGKKLRLIQE
                     YFMTSAGIQTIIKSYLKQGLPLTELHQKVSVHINDTHPAVAPAELMRLLIDDYGLEWV
                     DAWATTVKTMSYTNHTILSEALEKWDAELFKTVLPRVYQIILEIDHRFVAEMAQKGID
                     PQIIENTRIVKDNQIYMANLAIIGGYSVNGVAKLHTELLKTDTLKDFYALYPEKFNNK
                     TNGIVQRRWTQIAAPELSAAIDRTIGKGWRKDIHQLRQLSQFTEDPAVLNDFYQVKQA
                     AKQRLARYILEKTGLEVSTEAIFDVQVKRLHAYKRQLLNVLHIMKLYLDLKANPDLDM
                     VPRVFIFGAKAAPGYHFAKSVIKIINELANLINHDTSLKGKLKVVFLENYNVSLAELI
                     IPAADISEQISLASKEASGTSNMKFMMTGAITLATLDGANIEIKDEVGEENIVIFGMD
                     KDQVYDHYAKHDYYSRGLYESDPQIKAVVDAFVNGTIPNSQHEGMEIYDALITHNDEY
                     FLLEDFSSYVKAQAKIDRLYRQKDRWSKMSLINIAHSDKFTSDDTITQYAKDIWQLKR
                     "
     gene            56499..56696
                     /locus_tag="TVB59_000131"
     CDS             56499..56696
                     /locus_tag="TVB59_000131"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEL1009082.1"
                     /translation="MNPIFALALACFGVSLAEGFLMANLFKSASRQPEIIGQLRSLMI
                     LGVAFIEGTFFVTLVMAFILK"
     gene            56730..57446
                     /gene="atpB"
                     /locus_tag="TVB59_000132"
     CDS             56730..57446
                     /gene="atpB"
                     /locus_tag="TVB59_000132"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEL1009083.1"
                     /translation="MEEAKVPMVELGPITFNLTLLAVCIVTILLIFGFVFWASRQMTL
                     KPKGKQTALEYLISFVNGIGEEHLDSHLQKSYSLLLFTIFLFVAVANNLGLFTKLETT
                     SGYNLWTSPTANLAFDLALSLFVTLLVHIEGIRRRGFGAYLKRFATPWPMTPMNLLEE
                     FTNFLSLAIRLFGNIFAGEVVTGLIVQLANYRLYWWPIAFLVNIAWTAFSIFISCIQA
                     FVFTKLTATYLGKKVNESEE"
     gene            57464..57958
                     /gene="atpF"
                     /locus_tag="TVB59_000133"
     CDS             57464..57958
                     /gene="atpF"
                     /locus_tag="TVB59_000133"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEL1009084.1"
                     /translation="MSVTIGELIGNFILVTGSVIVLLLLIKAFAWGAIEAVLQARSQQ
                     ISQDIDQAEQARLNAQQLEKEGQANLEASRSEASQIVEAAKETGKAQETRIVAEATEE
                     ADRLKAAALTDIEHSKSEAISAVKTEMSDLTVLLAEKIMGANLDKAAQSQLIDRYLDD
                     LGEA"
     gene            57958..58494
                     /locus_tag="TVB59_000134"
     CDS             57958..58494
                     /locus_tag="TVB59_000134"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEL1009085.1"
                     /translation="MTKKEQALIEQYAKSLVQVCQERDTLEALQADVLAILEVFKATN
                     LAKTLSSLAVPRAKRLELVRQLQGDNIVYLNNLLEVMLQNEREAYLYQVLLRVLSELA
                     SVSNQYDVTVTSAVPLSEEQKQRVRTVVSKRLAVKTGRLIEKVDPSLIGGFMISVNNK
                     VIDTSIRRQLQAFKMNLK"
     gene            58510..60015
                     /locus_tag="TVB59_000135"
     CDS             58510..60015
                     /locus_tag="TVB59_000135"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEL1009086.1"
                     /translation="MAINAQEISALIKKQIENFQPNFDVTETGVVTYIGDGIARARGL
                     DNAMSGELLEFSNGTFGMAQNLESNDVGIIILGDFSTIREGDEVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPVDGLGDIETTGFRPVETPAPGVMQRKSVFESLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTSVAIDAILNQKGQDMICIYVAIGQKESTVRTQVETLRRYGAL
                     DYTIVVTASASQPSPLLFIAPYAGVAMAEEFMYNGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERSAKVSDDLGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLQEDLFNSGIRPAIDAGSSVSRVGGSAQIKAMKRVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQPLHKPLPVEKQVVILYALTHGFLDDVPV
                     DDILAFEEALYDYFDAHYDHLFETIRTTKDLPQEAELDVAIQAFKAQSNFK"
     gene            60033..60908
                     /locus_tag="TVB59_000136"
     CDS             60033..60908
                     /locus_tag="TVB59_000136"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEL1009087.1"
                     /translation="MAGSLSEIKAKIISTEKTSKITSAMRMVSSAKLVKSEQAARDFQ
                     IYASKIRQITTDLLKSDLTTGSDNPMLVSRPVKKTGYIVITSDKGLVGGYNSKILKSI
                     MDMIQEYHAAGDYEIISIGSIGSDFFKARGMNVAFELRGLADQPSFDQVGRIISQSVG
                     MFVNEIFDELYVCYNHHVNSLTSQVRVQRMLPISDLVAEEAAEEGVTGFELEPNRHVI
                     LEQLLPQFTESLIYGAIIDAKTAEHAAGMTAMQTATDNAKHVINDLTIQYNRARQAAI
                     TQEITEIVAGANALE"
     gene            61076..62482
                     /gene="atpD"
                     /locus_tag="TVB59_000137"
     CDS             61076..62482
                     /gene="atpD"
                     /locus_tag="TVB59_000137"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEL1009088.1"
                     /translation="MSSGKIAQVVGPVVDVVFASGDKLPEINNALIVYKDGDKKQKIV
                     LEVALELGDGMVRTIAMESTDGLTRGLEVLDTGRAISVPVGKETLGRVFNVLGETIDL
                     EAPFADDVNREPIHKKAPAFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLTQ
                     MGIYPAVDPLASSSRALSPEIVGEEHYAVATEVQRVLQRYRELQDIIAILGMDELSEE
                     EKTLVGRARRIQFFLSQNFNVAEQFTGLPGSYVPVAETVRGFKEILEGKHDHLPEDAF
                     RAVGPIEDVIEKAKKMGF"
     gene            62495..62911
                     /locus_tag="TVB59_000138"
     CDS             62495..62911
                     /locus_tag="TVB59_000138"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003088947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEL1009089.1"
                     /translation="MTQMTVQVVTPDGIKYDHHAKFISVTTPDGEMGILPNHINVIAP
                     LQVHEMKIRRVSEDDRVDWVAINGGIIEIKDNVVTIVADSAERDRDIDVSRAERAKLR
                     AERDIAEAETTHDIDEVRRAKVALRRALNRINVSKK"
BASE COUNT        17823 a        11947 c        14760 g        18488 t
ORIGIN      
        1 atatttttca aaaaagtatt gacttttaga ttgtaatata atattattta agtggttata
       61 ataagttaga ggtgttagta tgataaagga acagccactc tacttacaaa ttgttgatgt
      121 attagaggtc aaaattagaa ataccatgtc agctaatgat aaattgttat cagaacgaga
      181 gctaagtgac ttatttggtg ttagtcggat aaccattaga ttggcactta aggagctaga
      241 gctgcgtggg cttatttaca aacagcaggg caaggggacc tatgtatcag gcataaagga
      301 gcctgctaca gacctgtcct cagcctatag ctttaccgaa gagatgaaaa agcaaggtcg
      361 taagcctcaa acagtcattc tttcatttga aaaaatcaag accacagctt acttgtctgg
      421 tatgttagat ttagatgttg atactgatgt ttttgagcta gagcgtctaa ggattgcaga
      481 tggaaagcca ttaatgtttg agcgcactta tatacctgaa aggggatttg aggcgataac
      541 gattgattta ttggaaaaaa agcccttata tgatgtgttt gctgaggatt ttcaggaagc
      601 tatccgattg gctgatgagg agttttacgc tagtatcgct ctagattatg aagcaaagct
      661 attagggatc aaaaaggggg atcctgtgct gcatattatg cgtaagacct ataatgagaa
      721 aaataggcta atcgaattta cctttagtat tgctagagca gaccagttta ggtaccgtat
      781 ccagcaccac cctaacaaga agatatagga ggtaaggaaa tgtttacaaa aacacaagca
      841 gaactagagc tacttggcgc agctatcacc actagagaaa tcaagcagca gccagagcta
      901 tggtcagagg tctttgagtc ttttctgaag caaaaaaaag acctcttagc cttttttgac
      961 aggattattg aaagcgctaa cagaaacaag gtaaaaatta tttttacagg agctggaact
     1021 tctgaataca ttggcaatac catttgtcat tatttggaga tgactggtga cagggaaaat
     1081 tatttatatt acagcattgc ttccacagac cttgttgcag ctccaagcca gtatctcttt
     1141 gaagaggata cagtcgtgct tgtttccttt gcaagaagtg gcaatagtcc tgaaagtgtc
     1201 gctgctgtta gtcttgttaa tcagctggtg tcaaatcctt atcatttggt gataacctgt
     1261 gccaaagagg gggccttagc tcaaaatgct aagaaggaca aaaggagcta tttattcttg
     1321 ctgcctgagg cctcaaatga cgctggcttt gctatgacgg gaagctttag ctgcatgatg
     1381 ctagcggcct tgttgatttt tgatcaagcg cattcccttg aggagaaaaa atgctattta
     1441 gatcagattg taggtatggt ggcagctatt attcagcagg aggctgattt acaaaagctg
     1501 gttagcttag agtttcaacg cttggtttac ctgggatcag gagccttagc ggggcttacg
     1561 caagaggctc aattgaagat tttagaatta acagctggca aaattgcaac agtctatgac
     1621 tcctcaatgg gctttaggca tggtccaaag tcatttattg atgatcagac attggttatt
     1681 ggttttgtta gcaatgatcc ttatacgaga aggtatgacc ttgatgtttt agaagagata
     1741 agagaggatg ctattgctgt tgatacggtt gcattacagc agcaaggagg tgagggcttt
     1801 agtgggcatt gctttggctt agactcgtca atgctattgc cagatgctta tttggccttt
     1861 ccgcttgttt ttatcgccca aacgcttgct ttgctgtcgt ctattaaggt taataattta
     1921 ccagatactc cttcggccac aggaacggtt aacagggttg tccaaggtgt taagatttat
     1981 cactatttta agtaggagaa caagatgtac catttatcaa aagctaagta tcgtcttctt
     2041 gaaaaggtca gtcgtaaggg catcatttcg gccttggcct ttgatcaacg cggggtttta
     2101 aagcgcatga tggcagccca ccaagacaca gagccaactc cttggcaaat cgaagcccta
     2161 aaggctctgg tatcagagga gctaaccccc tatgcctcct ctatcctgct agaccctgaa
     2221 tatggcctgc cagccaccaa ggtgcgtgat gagaagtctg gcttattatt agcctatgaa
     2281 caaaccggct atgacacaac caccactagc cgcctgccag attgtctggt ggactggtca
     2341 gtcaagcgcc tcaaggaggc cggagctgac gcagtgaagt tcttgctgta ctatgatgtt
     2401 gatggtgatg agcgtattaa ccaacaaaag caggcctata tcgagcgtat cggctcagaa
     2461 tgtcaggcag aggagatacc atttttcctt gagctattga cctatgatga ggcgataaca
     2521 gacaatcaga gtgtagcttt tgccaagcta aaggcacaca aggttaatga ggccatgaag
     2581 gtcttttcaa ctgagcgctt tggggttgat gtcctaaagg tagaggttcc tgtcaatatg
     2641 gcctatgttg agggctttgc agagggtgag gttgtttaca gcaaagagga ggctatgcag
     2701 gcctttcgtg accaagaggc agctagtcac ttgccctata tttatttgag tgcgggtgta
     2761 tcagctagtc tgtttcaaga gaccttggtt tttgcggcag aggcaggagc taggttcaat
     2821 ggtgtgctgt gtggtagggc cacttggtca ggagcagtag cggtgtacat gtcagagggc
     2881 gaggaggcag cgcgtcaatg gcttcgcaca gagggttttg aaaatattga tcgtctcaat
     2941 caggtgcttg agaaaacagc cagcccttgg acaacaaagc ttactcttga tgaagcctag
     3001 taaaggcatg ataaaagcaa tactaggaca ttgcttctgt attattggta atcactggag
     3061 gacaaggcgt acttgaaaaa ttgccaatgc ttgtaggact cggtgtactc tagaatacgg
     3121 ccattatctg tcgaccgagt gagcttggtt tgaaggacac aaggagtgtt gtctatcatg
     3181 tttaaaaatg tagcgacatc tttaggcatg tgatccgtca gctgtgtttg ctgggtgaag
     3241 ctttgtgatc gcatttgaat gtgaaaatcc aaaaagaagc gcttataaag cgactggtaa
     3301 tcagctaaat cacgctcagg gcacagcagg taatcatgag gaatataaga tagctggtat
     3361 aaatagggct gctgattaat cgttcgtgta cgggagatgg tgtagtaaaa ttccgtttta
     3421 tgaagtttca agagatttag atagtaggga tcatttccct taactacact aaggacagtc
     3481 acctcctctt tttgatcctt aaaggtacct agataggaaa attggactag ctgttctttt
     3541 ctggtacggg taatgaaggt tccaagtccc tgccttcttc tgataaagcc ttctttttct
     3601 agttctttaa gggctcgaat gatggttatg gagctaacat gaaagcgttt aatcagctcg
     3661 gcttcggtat aaaatttgtc cccggtatgg tagtggccat tcagaatttg gttttgcaat
     3721 tcttctttga ttagtcggta ctttgggtat ttgatggtca tagttactca ctcaataatt
     3781 gtttagtacg attatagcaa aaatagtaag ctgatgtcat atcttaccag ttattgctca
     3841 gatagcttgt caatcagtca ttgatcaaag gctgatggtt aatgaataaa aggagataat
     3901 atgaagcaat tttgcataaa ggagcagttt taccttgatg gcaagccgtt taagatatta
     3961 tcaggtgcca ttcattactt tagaatagct cctgatagct ggtctagggt gctttatcag
     4021 ctgaaggcct taggctttaa tacagtagaa acctatattc cttggaatat gcatgagcca
     4081 aggaagggac agtttacctt tgaggggatt gcagatgttg aggcattttt ggatttggca
     4141 caggaatgtg gcctatatgc tattgtcaga ccctctcctt atatctgtgc tgaatgggag
     4201 tttggtggtt taccggcttg gctattaact gaaaattgta ggctcagatc aagcgatgag
     4261 gtctttctta agcatgtatc agattattat gatgtgttac taccaaagct ggtgaagcgt
     4321 cagttagata atggcggcaa tattctgatg tttcagcttg aaaatgagta tggttcttat
     4381 ggtgaagaaa aggcttattt aagaaaatta aaagagctta tgcttgctaa aggcattagt
     4441 gcccctctct ttacctcaga tgggccttgg ccagccacgc tagcatcagg gagtctgatt
     4501 gacgatgatg tttttgtgac aggcaacttt gggtcaaacg cttcaaagca atttgccagt
     4561 atgcaggatt ttttccaagc acatcaaaag caatggcctc tgatgtgtat ggaattctgg
     4621 ttgggctggt ttaatcgctg gaatgagcca atcattcgaa gggactccaa ggaagctgtt
     4681 gatgcaatca tggaagctat agagctaggc agcattaacc tttatatgtt ttgtggtggc
     4741 actaattttg gctttatgaa tggctcgtca gctcgtctgc aaaaggattt accacagata
     4801 acctcctatg attacgacgc attactagat gaggcaggga acccgacaaa gaaatatacc
     4861 ctgctgcaag aacgtctcaa ggagtgttac cctcaattat cctttgcaga gccaatgatc
     4921 agttctacga tggccttaga gtctatcaag ttgtcggcaa gggttagtct ttttaagaca
     4981 atcaaaaatg taagcgctat caagaaaagt ttttatcctt gtaatatgga ggagctagat
     5041 caaccaacgg gctacctact gtatagaacg cacctcgcta gacatagcaa ggaggagcgg
     5101 ctcagggtca ttgatgctag agaccgcatt cagctctttt tagatgaaaa gcacgtgaaa
     5161 acccagtatc aggaggaaat cggtcaggat atactgatac atcaagaggg tgagaccaca
     5221 cagcttgata ttttagtcga aaatatggga cgtgtcagct atgggtacaa gctgacagca
     5281 ccaagccaac aaaaaggatt aggcagaggc ttaatggctg acttgcattt tgtaggtgat
     5341 tgggagcatt ttccactaga ttttcaagag ctggattgga ttgatttttc tgcaggttgg
     5401 accgatgagg tgccaggatt ttacgcctat gattttgatt gtcagcagcc ggcagatacc
     5461 taccttgatt tgagtcaatt cggaaaagga attgcccttg taaatggtgt taacctagga
     5521 cgtttttgga aggtcggtcc aacattatcg ctttatattc ctaagggact attaaaacaa
     5581 ggtcaaaata gactgctgat atttgaaaca gaagggcagt ttagtgagtc aattcgttta
     5641 actaaggaac caatttataa atagataaaa ggagaaaact tatgacaatt gttgcagcac
     5701 gtattgacgg ccggttaatt catggtcagg tagctaatct atggacgaca aagctaaaca
     5761 ttagccgtat catggtggtc gataatgagg tgattagcaa tgaccttgaa aaaacagcac
     5821 tgaagctagc cacacctagc ggtgttaaat tatctatctt atctgttgaa aaagcagcca
     5881 acaatatttt ggaagggcgc tatgattctc aacgcttgtt gatagtagcc agaaagccgg
     5941 atagcttttt ggagctgatt caaaaagggg ttgctatttc agagttaaat gtcggcaata
     6001 tgtcacagac accggagact cgtccagtaa cgcgttctat taacgttgta gacgaggata
     6061 tagaggcatt caaggctatt tcagccaaag ggtgtcatct cattgcccaa atggtgccta
     6121 atgatgcccc agcagacttt atgccgctgt tggataaggt tgattaagat gtgtcaaatc
     6181 aaaaacgaat ctgtttcagg aggtaaaagc ttatgattca atggtggcaa atcctattat
     6241 taacactcta ctcagcttat caaatattag atgagctaac aattgtctct tctgcaggct
     6301 cacctgtatt tgcaggattt atttcaggta tcatcatggg agatgtgcaa accggtcttt
     6361 ggattggtgg tagccttcaa ttgatggtgc ttggtgttgg gacctttgga ggagcttcgc
     6421 gtatcgatgc aacctctggt gcggttattg cgacagcctt ctcggttgct caaggcatag
     6481 agccagaatt agcgatttca accattgcag ttccggtagc ggccttgctg gtttatactg
     6541 atattctagg acgcttttca acgaccttct ttgctcaccg tattgaccgc catgttgaaa
     6601 actttaacta ccgaggcatc gagcgtgatt accttatggg agctgtacct tgggccctat
     6661 cacgtgctct gccggtattt ttagcggtct ctttaggtgg tggtgcggtt gatacagttg
     6721 ttaagttcat tgaccattat gaatggctag caaatggtct aactcttgca ggaaaaatgc
     6781 ttccaggctt gggctttgcg atcttgcttc actacctacc agttaaacgt aatctccatt
     6841 atctggcttt aggttttggc ttgacagcaa tgctaacaac catttacacc aaccttcagg
     6901 tagctggagg cgcccttgca ggagtagcca aggatttcaa tgccgcacca ttcaaggggc
     6961 tgccaatgat tggtattgct attattgggc tttccttggc aaccctccat tataaaaatg
     7021 gtcaacaagc acctgtagct gaacaaaaac ctggggtatc agaaagtggg gaaattgaag
     7081 atgacgaaat ctaattataa attaaccaaa caggatttta atcaaatcaa taagcgcagc
     7141 ctgttcacat tccaatgggg ctggaactac gagcgtatgc agggctctag ctatctttac
     7201 atgattttac cacagcttcg taagatttat ggcgatggaa ctccagagct aaaagaaatg
     7261 atgaagacgc acacgcagtt ttttaacaca tcaaatttct ttcatacgat tatcacagga
     7321 attgacttgg cgttggagga aaatgaagga cttgcctcaa aagatgctgt taatgggatt
     7381 aaaacaggct taatggggcc atttgctcca attggtgatt cggtctttgg ctccttagta
     7441 ccagctatta tgggctctat agccgcaggt cttgctaaag aaggggtttg gtcagggatt
     7501 actggtgtat tgatgtgggt atgtactcag atgatcatca atgtgtttcg ttggaagcag
     7561 cttgaaattg cttataaaga aggtacaaag ctcgtcacca ccatgcgtga taagctaact
     7621 gctgtagtag atgcagcctc agtcatggga gtattcatgg taggggcctt aattgcaaca
     7681 atgattaatt ttcagtttac cgcagcaccc aaaattggag agaaagttat caatattcaa
     7741 gatttaattg ataccatttt tccacgtcta gttccagcct tatttaccgg aggtatcttc
     7801 tggctgctag ggcgtaaggg catgtcacca actaaggcaa ttgttgtgat tattttattt
     7861 gccttagtga tgtcttattt caatatttta ggagtatagc tgatggcgca aaccttaatt
     7921 ctcattagtc atggagcttt ttgtcgagag ctaaaacaga gtacagaaat gattatgggg
     7981 ccacaggaca atattttaac agcagagctg caaccaaacg aaggtgccga tgactttaaa
     8041 gaaaagcttt taaggctaat tgcaggttta gatgacgtcc ttgtgtttgc agatttgatg
     8101 ggtggaacac cctgtaacgt tgccagtcgt ttgttaatgg aaggacatca gtttgagctg
     8161 tacgcaggca tgaatatgcc aatggtcatt ggtttcatta atgcctgttt gatcggtgaa
     8221 gcgtttgatt tcaaagcctt tgcctgtgac aatattcacc atgtcaatac cattatttca
     8281 gctctagcag atgatgatga cgactaacca agctcgctta tttgtcacgc accttacgga
     8341 gcgaaacgga ccaagagccg cataatcaaa aaagacactg ccaaatcttg gcagtgtctt
     8401 tgctgtaagc ttattttgct gcgtttgcgt ctttgagacc gtatttcttg ttgaaacgat
     8461 ccacacgtcc atcggcttgt gtaaactttt gacgacctgt gtagaatggg tgtgagtctg
     8521 atgaaatttc tacacgaaca agagggtaag tttccccttc aaactcaatg gtttctttag
     8581 aggtcttagt tgaaccgcta aggaatttgt agcctgtagt tgtatcaagg aaaacaactg
     8641 gacgataatc tggatgaatg tcttttctca tcttaaaaaa gttcctttct gccatgatac
     8701 tgtccgtatc atagttatta actactctag tttaacaaaa gttagtaagc ttgacaagct
     8761 ttttctatca ctattcatca ataagatgat aagtcttatg ttaagagatc aatcagctct
     8821 tggtagattt gctcattttc ctctaagcct gatgacgtgg caccgctagc aagagggtgc
     8881 ccgcctcctt gatgacgctt agcaatacca ttgatgacct tttctttact gcgcatgcgt
     8941 actcggtact ggccatctgg cagctcaaca aagataaccc aagcctgcac cacgtctatt
     9001 tttccaggag cagagacaat cgctgagctt tctgccaagc taataccaaa ggaatttagg
     9061 acctcctggc taagcagtag gcgggctgca ccactgtcat ctatatcaag ctgctcaaaa
     9121 acatagcctt gtagcttggc aattttaagt ggaaaggaat ccatctgcct cgaaatagca
     9181 gcaaagtcaa aggcataatt tcttaattgg cttgcaatgg ccagtgtttt actgcttgtt
     9241 gaggcataga gaaagcgtcc tgtatctccc acaatgccag tatataatag tctagctgcc
     9301 tcatcagtta aagccaagcc ttggctaaag gcaaattcag caataatctc actagcactt
     9361 gaggtcttgg tgtcaacgta ggagagatca ccatagacat catcgttagg gtgatgatca
     9421 attttaatga ggcaagcgcc cattgtgtag cgctcatcat caatgcgggg gcgattggca
     9481 gtgtctgtaa caatcactaa agcttcctta taatcatcgt cggacacctg atccatgaga
     9541 ctaatccaag ccagactagg ctcatcaaag cctgttatca ggaccttttt gtcagggaaa
     9601 ttatgcctga taatctcttt aagtcctgct tggctcccta gagcatctgg atcggggttt
     9661 tggtgccgat gaatgatgat ggtttgatag tgcttaatgt gttctaaaat agtttgaaac
     9721 gttgtcatag gtatccttta gtttttgatc atatcaatgt gaggaatatt gtcttccaga
     9781 taaatctcag agactgcttt aaacccaaat gagctgtaaa aaggctcaag ataagcctgc
     9841 gcttgagcgt agacgggaag ctttggaaag tgctgttgac aataggctaa ggcttgatga
     9901 actaagtcac gtcctagtcc tgttcgcctt gcattttgtg ctaccagtac tcgtcccagc
     9961 tttatgctat tgtcagttgg gattaagcga cagtaggccc taagctctga atcaacctgc
    10021 ttgaaaagat ggatagcttt ttgatccaaa tcgtcaatat caggataggg acattgctgc
    10081 tcaaccacaa aaacagccac acgctcttta tagatggcaa acaattcatc ttttgttaac
    10141 tgatcaaatg ctttaacaac ccacattagc tagcctccaa aatcactggt acaatttcct
    10201 ttatgataac ataatagcat atatcagcca taatggaacg aaaaaaacct gactcttaat
    10261 ggacgatgtc gtgatgataa ttacatcttg tctcaaaagc tggtaatcat cacaggcaca
    10321 gaaaaatgtg ccccttctgt tgctttttga gaaaaagttc acttgctttt tggtagtttt
    10381 ttggtatcat actaaaaaat agacttaatt aaggagatac agcttggaaa caaaagattt
    10441 aaagaagctt gctaaagctg agctgcactg ccatttagac ggttctttgt cattagacac
    10501 tattcgtcag ttggcggctt tggcgcaggt agatgttcct caagatgatt ctgagttaaa
    10561 gcagctggta accgcaccgg aaacctgtga atccttgatg gattatttaa aaacctttga
    10621 tgttatcaga ccattattac aaacgcctca ggctttaaca ttggctgctt atgatgttgt
    10681 gaagcaggct gcccttgaaa atgtcatcta cattgaaatt cgatttgctc ctgagttgtc
    10741 aatggatcag ggcttgaccg ccactcaggt ggtagaggca gttttaaaag gactcgagca
    10801 aggacaaaaa gagtttggca ttgtcgctaa ggctattgtg tgtggcatgc gtcagtcctc
    10861 actagacatt agcagagaga tttttgcaaa tgtcttagag tgggccaata aaggcttggt
    10921 aggctttgat tttgcaggca acgagctgga ctttcctcca gctgtcttag cagatttgat
    10981 caaagagacg caggcctatg ggttaccatt tacgcttcat gctggtgagt gtggctgtcc
    11041 aaactatatt gttgatgcta ttgatttagg tatcaaacgc ttagggcatg tgacggccat
    11101 tcataaccaa aaggatttat tggccaagtt tatcgccaat gatgtgacag cagagctgtg
    11161 cttcactagt aatctacaaa ccaaggctgc taggactgtt gaggactttc cttatatgca
    11221 gctaaggcag gctggcgcta aattatccat taacacagac aatcgaacag tatccgatac
    11281 caatctgaca aaggaatatg aactgtttgt caagcacttt gagacaagcg tcacagactt
    11341 tttagagcat aatcgtgatg ctattaaggc tagttttgcc agtccggctg aaaaagaagc
    11401 tttattggat cgtttggaaa aggcttatca gtcttacatc aagaaataat gcttttcttg
    11461 gcaaagtatg ataaaatata ctgacattta gttattttgg gaggaaatta tggcattagc
    11521 caaaatcgtt tatgccagca tgacaggaaa tactgaagaa attgctgata ttgttgctaa
    11581 taaattgcaa gaattgggac atgatgttga ggttgacgag tgtacaacag ttgatgcttc
    11641 agagcttgag gctgctgata tggcaatcgt tgcgacctat acctatggtg atggggactt
    11701 accagatgag attgtcgact tttatgagga cttgcaggat ttggatttgt caggcaagat
    11761 ctacggtgtc gtgggctctg gtgatacctt ttatgattat ttctgcaaat cagttgatga
    11821 ttttgacgaa cagctcgctg ccactggtgc cactaaggga gctgactcgg ttaaggttga
    11881 tttagctgct gaggaagagg atattgctcg cctagaatcc tttgctgagc aaatgtcaca
    11941 ggcattagag gcataagtaa gacttttgat acagattggt aaaacggtca gtggaggctt
    12001 gcgtttttta ccaccaaatg catgaaaaac tgatattttc tgatcgtttt ttcatgacta
    12061 tgtgctcttt ttcaagaaaa gtcatgccat tattagcctg aatgcaaaca attgatagtg
    12121 tcaaaatgtt gatcatatag taaaaaaatg catgtgacta gaaagcagtt acatgcattt
    12181 tcgtcatgcg tttgtcgtga ggcattttgg gggttacttg cttactgagc tgaaattcac
    12241 tataataaaa agataaataa agaaaagaag aagttaggtg aatgatggga ttagagacca
    12301 tacgacaaga cattaatgct gttgatcgtc agttgattgc tttgctggaa aagagaatgg
    12361 tcttggctga ccaagtagcg gcctataagc aggtacatga tgtgccagtg cttgatcaag
    12421 agcgagaggc tgaggtccta aggagcgtgt cacagcagat tcggcataag gcctttgagc
    12481 ctgccattct tgagctattt aagacaatta tggcagtatc aaggcgttat caggctgagc
    12541 aaatagcggt tggttcaaat gatgatgaag cctattaaaa acaatcaaga catcagtata
    12601 ggtgataatg tctatttggc ttttgcagcc ctgctcgttg gggtggtggt aggtgtgata
    12661 gatactgttt ttggacaagg cttgttgctc ttgtctgctg ttcgtgatgc tcatctcatt
    12721 tacctgttac cctgcttagc tcttgctgga cttgtgattg tgttcttata tgagcaatat
    12781 ggccaaatcg ctaagcaggg gatgggctta gtttttgatg tggggaatgg tgaaaaaaca
    12841 agactaccac tggtgttgat tccgttgatt atcctctcaa cctggctgac gcatttatgt
    12901 ggaggcagtg ctggtcgtga aggcgtagcg gttcaaattg gagcgacagg tcacattttt
    12961 ttggacgtct tagacatctt aaggacaagt cacagctgtt tttagtcatg ggaatggccg
    13021 caggctttgc gggcttattt caaacgccaa tgacagcggt tgtttttgcc ttagaggtcc
    13081 tgttgctagg aaatataagc tatttagcct tgctaccttc tcttatagca gcctttaccg
    13141 cctcttggac ctctcattgc ctaggcttag aaaaattttc agtcccgata gccaaggcct
    13201 tgaaaatcac cccgataacc tttgggaaat tagtgctact aggccttatt tttggcttgg
    13261 ctggtaatct ttttgcctcc ttgttagcaa gggctaagcc atacattgca gcaaggctgc
    13321 caaatcctta ttatcgtgtg ttgcttgttg gtggttttct atcgcttagc ctgctgctgt
    13381 gccattacgg gcgctatagt ggcctaggga ctaacttaat tacagcggcc tttagtcatc
    13441 agcctattgc taattatgat tggctattaa agctcttgtt taccattatc actctctcgg
    13501 ctggctttca gggcggtgag gtcactccac tttttgctat tggtgcggct ttaggaattg
    13561 tcctagcacc atggcttggc ttgccggctc agttggctgc agcccttggc tatgctgcgg
    13621 tatttggcag tgccaccaat acctttttag ccccgatatt tgttggatta gaggtttttg
    13681 gtgcaacaaa cgcaactgct tactttatcg tgatagcctt tgcttatatg gtgagccgaa
    13741 ggcattcaat ctacactaag caaagggtga ccactagcat cgcttcctag tgtcttggtc
    13801 agttttttgg agaaaatagc tttacaagtg gggcttattt tgttacaata ggctccgtgt
    13861 gtaatggacg cacaaaaatt acggctaatc cgctaagact cgcgcttaag attagtaaga
    13921 taaggagaat aaacaatgaa tccattaatt caaagcttga cagagggtca acttcgtact
    13981 gatattccta gcttccgtcc tggtgacact gttcgtgtgc acgcaaaggt tgtcgaagga
    14041 tctcgtgaac gtatccagat ctttgaggga gtagtcattt cacgtaaaag tcaaggtatc
    14101 tcagagatgt atactgttcg taagatttct agtggtatcg gtgtagagcg taccttccca
    14161 attcacacac cacgtgttga aaagattgag gttgtgcgtc atggtaaggt tcgtcgtgct
    14221 aagctttact acctacgtgc cttgcaaggt aaggcagcgc gtatcaagga aattcgtcgc
    14281 taaaaagagc atacgagagg tttttcactg tcttatgaaa ggactgctgg agcagcaggg
    14341 tctttgggac aagctttttt tcgcaggtat gtgaacctac gctcaattca agacatatca
    14401 aaggctcatt ctatgataga gtgggctttt tgattgtgat catgctttag tgcctaaata
    14461 aatgacagca gcctgactaa tgaaaggctt acttgacttt ggaaatgctc aaggcttgcg
    14521 ctaccagata gaagctgaca tcatgccata gcagtcaagg ggaagaagga ctagattttt
    14581 tggcgaggtg ttgatctgtg accctgatgt tgttgggaat atgagagtaa tttaaaattt
    14641 cgtcttgcat tctacctttt tctaggttac aatagacaag taacctgatt agtgaagcta
    14701 aaagacgtag cgatgggttc taaaaaagaa tgattctggc gtttttggct aacctaagct
    14761 gatagctttg ctaggcagtg tcttagtcat ctggtcagtc ctgctagttt aacggataaa
    14821 acaagcgcct cctaagcgct agctgtgggt tcgattcccg cgcgggacat taaaaacaaa
    14881 gtaaaaagag tctgagaagg tttgagctgc ccctaattgt tagatttttt tctaactctt
    14941 gaagtgtggg tcaaagacta tttgtctcag gactcttttt aattggtttt tactaagctg
    15001 cttcatctag ttcttcagtt gctaagttgt ttccttcttc tgtatgttgg ttttcatcaa
    15061 gtagcattcc tgtgcggtaa tctaatgctg ccaaaggtga tacattatcc agaacaactg
    15121 aggttatacc ataatgatca acggattctt tgttgcctcc caatttgatt tggaggagct
    15181 ctccgttttg atcaattcca acgtactgta acactacttg acgaggaact aattcatcat
    15241 tctgataaat aggagttacc ttataatcta gccaaaagtt agggtgtatg gctaaccaat
    15301 tgtctagtct attttcataa taaagcattc ctaaaggatt tttatcacta aaacctgtat
    15361 taaggtattt tgtcatagta actaaatttt tgggttcatc atttaggccg ctaaactgat
    15421 aaccgactag atgtccgcga tccattaacc aagtcttttt ccctctagaa ttaatgactt
    15481 gatagttatg ccagccggga ggattaaatc taagcgcttt tcttttgaga gttggttcat
    15541 cttgatcttt gagttgtatg tgtgcatagg tggctctttg taaatgatca agatctccca
    15601 gagctatttg gtattttcca gtaaacggta aaattcctgg tatttcggta gcttttgttc
    15661 ccaatgatat ttccgttgta tctgggaagg ttctaagttt tcttgcagat tgaacagagt
    15721 tagctgtgaa aatagtcaga atagttaaca aaacaattgt tagacttttc cagttacggc
    15781 gacgtgattt agacatatca atgccctcct ttttttgttt acgagttaag tatatcactt
    15841 ttaattaaaa aaacttaaaa ttaataaaat tattttaatt ataatattca tctaaattat
    15901 ctttattttt aattcaaaaa tataagcaat tgattcacat aaacaaattg agacgaacag
    15961 tagattgtag ctatatcaca ggtgagatag taatgatcgt gcgaaacaat aaactgattt
    16021 ttccatgcgg gatatttgtt atcagtgagt tgaatggaac tagcagctat tgttttattg
    16081 ttagtcatct agtgttttta aggtgcttat tttctgttac aacagtgatg acaacaggtt
    16141 aagctaagtt cgatggagct tggtttttta ttgttacaag aaagctcata gatggtgatt
    16201 gcattctttt atcatatgac aatgtttcta tttttgacaa atattattgt caaaaagtaa
    16261 atgatctgtt acactggagt tggactcatg aaagaaaaaa gtaatcagta ggataacaat
    16321 aacaaagcta ttttaagctt ataccattgt gtcaatggat tgttgccgga aatgactggt
    16381 gctttctgtt caatcaggag acagcattta ttaggagtga agcatggctt ataggttgag
    16441 aaatcggctc aaggagctac gagctagaga tggcattaat cagacgcaga tggcagcatt
    16501 agcaggtgtt tccaggcaga ccattagcct cattgagcga aatgaataca caccatctat
    16561 tattattgca atgaaaattg ctaaagtatt taatgaacca attgaacaag tatttagctt
    16621 agtggagggc gagagatgaa agcttttatg acggaaaagg acagtacgtt ggtgagaata
    16681 cttaagtcat tactgcttgg atcagggatt ggcttagtgt taggtggcct tgttggtttt
    16741 ggtttagcta ggtttaacat attagaaaat ggctttccga tatcagaaga agacaccata
    16801 actggaataa agtggggaat gagacccctt gttatcgtgc ttatgctgct gagcatttat
    16861 gatatttatc aagttgtcaa agaatatgct agatatgtca agctaagcga tgatgaaaca
    16921 gaggagctgt accgttacat taatcttaag catgcctatg ctttaggatt tagcgctatg
    16981 gctatggtct tgaatatagt cgttttttct ttgggatata gggtgcctat tgctaataat
    17041 gctagctatc ttggtttgac ttttcctatt tacgaggctc tgatgcttgt ggttattagt
    17101 gttctccatg cttatatttt gaaggtttat actcggattc gcggggtcaa gatgacgctt
    17161 gctcctacct taaaggaatt aaagcagaat atcttacaac aggacgaggc agaattgcag
    17221 gctaattatc aaatgtcttt tgaggttgtc atgggcctta gtggctttat attaccaggc
    17281 atttacgtaa tattattgct tttatctatg atttttcaaa gggttgagct gaccggacta
    17341 atcattactg ctagtattca cctctatatt ctggtgaaat cctttaaatc agcacatgat
    17401 ttttataggt aaggcgtaag gttttaccta ctcaagaatt gttatacagc aaaaaagctt
    17461 tgataagcca ttactggcga tcaaagcttt ttgtgtttgt tgaaaaagag gcttttttga
    17521 aagagctgtt ggctgagata gcttgtcaaa cctacaattg caagcggcac aaggctaatg
    17581 agaggttgtc cggtaatttc aatgagaaaa agaggagcag taagaggtat ctgattaatg
    17641 attcccaaaa agagggtcgc tccaatgaca atggccaagg gaagtggtac agagagataa
    17701 cctagctgat tgctaaggct tgccagtagc aagccactag ctcctccaag catcatagaa
    17761 ggagcaattt tgcctccttt agctccagag gcaaatactg catagacagc agctgcttta
    17821 cttagtaaga gcgaggcggt ataagatagg ctgacatcat ggtgtagcag caggaggaga
    17881 ccggccttgc cattgcctaa aatctctggg aaataaaggc ttaaacaagc actaaagcca
    17941 aaagccccta agacacgagg gataaaccat cggctcttag gctttgcctt tggtgcgttt
    18001 tggagcagct gctggtagca aaaggccaga aatgctaaga tgggactggc aatgatagcc
    18061 caaaggactg ttgtcagttg ccaggcttgt gggagaatga gatactgtat gtcctgatgt
    18121 ccgcttagaa caagcacact ttgaacagca gtaaaggcag ttatagctgc cgcgtaaatg
    18181 tgtttaactg agcatttttt gacaatagcc tccatgataa agacaatcgt agctaatggt
    18241 gcctggtaaa cagctccaag ggcagctcct gaagcacagg ctaaaagcaa tccttgctct
    18301 gctgctgatg cgtttatagc tttattgcaa gcggcagtca gtgccacagc aacctcacgt
    18361 gaagcacctt cacgaccgac aggtgctccc atggagacgg ttattaattg cagccagcca
    18421 tgacaaaatt gtgtccaagg gctgaaatcc ttttgctgac tgagtgtttg ttggataggc
    18481 tgaataggct tggctttttt agcaagtagc tgccagccga gaccagcaat agctccagcc
    18541 aacaatagag ataaaaaacg cctttctgga gctaccgttg caatcatggt gctaaaagac
    18601 ccagattggt atccaaagct aatagcctgt atgaaatgaa tggcttgagt gagcacgtaa
    18661 gccaccacac cagcaatcac accagctacc accagttggc ccgtccatgt taagaaagta
    18721 atcaatcgag taatcatatc ttttattata gcagataaaa agagcctgag actactcagg
    18781 ctccaaaata tagataaatc caatcttcat gagaagctgg acttatagcc cataattgta
    18841 atcgtcatca gtcatagctt caacagtacc aagaaggtag ccattaccaa cttgagagaa
    18901 gaaatcgtgg tttgacgtgc cggttgaaat accattcata acgattgggt tgacatcatt
    18961 ggcagtgtct ggaaaaagag ggtcctgacc aaggttcatc aaagccttgt tagcgttgta
    19021 gcgtaggaag gtcatcactt cctcggtcca gccaacctca tcatagaggg tcttggtgta
    19081 ttgctcttca ttttcatata gctgatacag caggtcatac atccagtcac gaaggctttc
    19141 ttgctcactc tctgatagct cattaaagcc cagctgaaac ttgtagccga tataagtgcc
    19201 atgaacggac tcatcacgaa tgatgagctt aataatttca gcgacattag ccagcttatt
    19261 gttgcccaga taatagagtg gtgtaaaaaa gccagaataa aatagaaagg tttcgagata
    19321 agtcgaggct accttttttt gaagggcact gccattttca taaatgtcgt tgattatctt
    19381 agccttattt tgaagaaata cgttgttgtt ggtccactca aaaatgtctt caatttcttt
    19441 tttggtgttt agggtcgaaa agattgatga gtaggattta gcatggacag actccataaa
    19501 ttggatattg ttaagaactg cctcttcatg cggggtgcgc acgtccttgc gaatggcttc
    19561 gactcctgac tcagactgca tcgtatcaag aagggttagc ccgccaaaga ccttacctac
    19621 taaatccttt tcaacagcag ataatctgcg ccagtcatca aggtcatttg atagtggaat
    19681 acgtgtatca agccagaatt gctccgtcag cttttcccag gttgacttgt caatgacatc
    19741 ttcgatttca ttccagttga ttgcttcata gtatgtggtc atgagtttct ccggtagatt
    19801 gtaatatagg gttaggtatg ctaggaggag agccttgagt gctggtctat cattaggaca
    19861 ggtgcactga cacatcagct aggctctgac attaaggact ggtccacctc actgccattc
    19921 acttggttag atgacacagc tttcacactg attggctccg acctcctcgc catcatcggt
    19981 aaaggtgcgg atataataga ttgattttat ccctttatta aaggcgtaat gtctcaaaat
    20041 agataggtca cgagtggttt gcttgctttc tgttttccat tcgtagagct cctttggcaa
    20101 ttcgctgcgc aaaaagagtg ttaacgacag tccctgatca acatgctttg tagcagctgc
    20161 atagacatca atcacctttc tcatgtccat atcataggca gatgtgtagt aaggaatggt
    20221 gtctgtagat aggccgttgg ctgggtaata aatcttgccg attttctttt cctgacgttc
    20281 ttcgatccgc tgagtaatcg ggtgaataga agcagagcag tcgttgatat aggaaattga
    20341 tccattagga gcaactgcca gacggttttg gtgataaagg ccatctgtca taatcgcttg
    20401 acgcagcgcc ttccagtctg ctgcttgcgg aataaagtga tccttgaaaa ggcttttaac
    20461 cagctctgat tttggcacac attctcctgt gatgtactgg tcaaaataag caccgctagc
    20521 atatgttgat ttttcaaagc caacaaaggt tgtctgacgc tcgcgagcga tctgattgga
    20581 ttcgacaagc gtccagtaat tcatcagcat aaagtaaata tcagtaaatt cgatagattc
    20641 tgggctgcca tattcgatat ggtgctgagc caaataggaa tgaagcccca tagccccaag
    20701 gccaaaggta tgtgcttgac tgttaccatt tttaacagtt gggactgctt cgatattaga
    20761 ggagtcagtg acaaaggtca gggcacgtgt catggctctg atggaacgac caaagtcagg
    20821 tgacgtcatc atgtttaaga tattagttga tcccagattg caggaaatat cagttcccat
    20881 tttgacaaac tcctgcgcat cattaatgag actaggcgtt tgaacctgta gaatttctga
    20941 gcataggttg ctcatgatga ttttaccgtc aatagggttt gacctgttgg cagtgtcgat
    21001 gttgataaca tagggatagc cagattcctg ctggagcttg gaaatctctg tctccaaatc
    21061 acgtgctttg atttttgttt tggtgatatt aggattggca accaattcgt catacatgct
    21121 agtaatatca atgtagttaa atggcaggcc gtattctctt tcaacactat aagggctaaa
    21181 gagatacatg tcagcattgt gacgagcaag ctcataaaac ttatctggta cagtaatacc
    21241 aagtgacaat gtcttgaccc gcaccttttc atctgcattt tcttttttgg tagacaaaaa
    21301 agcgataata tcagggtgaa agacgcttaa atacaccaca ccagcccctt gacgctgccc
    21361 tagctggttg gaataagaaa agctgtcctc aaatagcttc attacaggca caacaccaga
    21421 agcagctccg gcatagccct tgattggagc gccagcctca cgaaggttgg ataggctaat
    21481 gccaacacca cccccaatac gggataattg caaggcagaa ttaatagagc ggccaatggc
    21541 attcatatca tctgtcacct gaaggagaaa gcaagaaacc agctcaccac gacggctccg
    21601 tccagcattt aaaaaagaag gagtagcagg ttggtaacgc tgattaatca tctcaatggc
    21661 taagtcctta gctaatgttt catcaccatc agcaaaataa agggcattga acatgacccg
    21721 atcctctatg ctctctaagt agaaattgcc atcattggtt tttagggcat actgctgata
    21781 aaatttatag gccgccataa atgatttaaa gcgaaagccc tctgcttgaa tgctcttggc
    21841 tagatggctg ataaattcag gagaatagtt ttggataaag gctgattcaa tatagtcatt
    21901 gtctacaaga taggcaatct tttcgttgat agaagaaaat gacatggtgt taggaataac
    21961 attttcggta aaaaaagcct ccaaagcttc cttgtcttta tgaagtggaa tgctgccatc
    22021 aacaggacgg ttaatttcat tgttgaggcg aaagtaagaa atatcgccaa gatctttgag
    22081 actcatatca attgttcctt gtctagttaa ataatatctt ttaattttgc tggctgaaac
    22141 cctgagaata ctatctgctc tgtctcaata acaggagcag cagtaaagcc aaggctctta
    22201 acatagtcca ctttttctgg atgctcatca atattaatct cttggaaagc agctccatgc
    22261 tgttctaaaa atttcttagt cattttgcac tgcatgcaat tgtgctttga gtatactgta
    22321 atcattgctc gtccttccaa ctattagtct ttcactcaat tttaggaaaa atcaaatgac
    22381 tctaatagga tataaaaaat gttcctaaaa agcaaacgat ttatttcaga atagcacaag
    22441 atattgtggt tgtgtgtgag aatatttcta aatattgtgt tatcctctct tatcactgat
    22501 aattgctaca agaggcttgt agttcttaaa tgcatactaa tcaggttgga aggcttattt
    22561 gacattatga aaatcatcat gtaagaaata ttgacaacaa atgaaaatac aagaaaactg
    22621 tttcatgatt ttttcttgtt agaacattta accttgaaaa taaaaaagca ttgtgctata
    22681 atcacttatt gtaagggtta tcatgtgata gctcgaaaat acacaattca aaaggagaac
    22741 catattatgg cttcaaaaga ctttcacatt gttgcagaaa caggtattca tgcacgccca
    22801 gctaccttac ttattcaaac agcaagcaaa tttgcttcag atattacact tgactacaaa
    22861 ggtaaagcag taaatcttaa atcaatcatg ggtgttatga gccttggtgt tggtcaaggt
    22921 gctgacgtaa caatcacagc agaaggcgct gatgcagatg acgctattgc ggcaatcgaa
    22981 gaaactatga ctaaagaagg attggcataa gactatgaca gaaatgctta aaggaatcgc
    23041 agcctctgac ggtgttgctg ttgccaaagc atatctgcta gttcagccgg atttgtcatt
    23101 tgagactatc acagtcgagg atacaaatgc agaagaagct cgccttgatg ttgcactaca
    23161 agcttcacaa gacgagcttt ctgttatccg agaaaaagca gtagaaagcc taggcgaaga
    23221 agcggcagca gtttttgatg cccatttaat ggttcttgct gatccagaga tgatcagcca
    23281 aattaaagag actattcgtg cgaagcaaac gaatgctgaa acaggtctaa aagaagtgac
    23341 tgacatgttc atcacaatct ttgaaggcat ggaagacaat ccttatatgc aagagcgtgc
    23401 ggctgatatt cgagatgtcg ctaagcgcgt cttggctcat ttattaggtg ttaagcttcc
    23461 aaatccagct acaattgatg aagaagcaat tgttattgca catgatttga ctccttcaga
    23521 tactgcacag cttaacaaac aatttgtaaa agcatttgta acgaacattg gcggacgtac
    23581 gagtcattcg gctatcatgg cccgtacact tgagattgcg gctgtgcttg gtacaaatga
    23641 tattactaag cgtgtcaaag atggtgacct tattgctgtt aatggtatca ctggtgaggt
    23701 tattattgac ccaagtgagg agcagattct tgctttcaag gaagctggag aggcttatgc
    23761 gaagcaaaag gctgagtggg ctctgcttaa ggacgcacaa actgtcacag cagatggcaa
    23821 gtactttgaa ttagcagcaa acatcggtac acctaaggac gttgaaggtg tcaacgataa
    23881 tggtgctgag gcggtaggtc tttaccgtac tgagtttctt tatatggatt ctcaggattt
    23941 cccaaccgaa gatgagcaat atgaagccta caaggctgtt cttgaaggaa tgaacggcaa
    24001 gcctgttgtt gttcgtacaa tggatatcgg tggggacaag gagcttcctt actttgattt
    24061 accaaaggaa atgaacccat tccttggttt tcgtgcctta cgcatttcaa tctctgaaac
    24121 aggtaatgct atgttccgca cacaaattcg tgctttgctg cgtgcttctg tgcatggtca
    24181 attgcgtatc atgttcccga tggttgccct tctaaaggaa tttcgtgctg ctaaagtcgt
    24241 atttgaagaa gaaaaggcta gcttgctgtc tgagggtgtt gcggttgcag acgatattca
    24301 ggttggtatc atgattgaga tcccagcagc agcaatgctt gctgaccaat ttgccaagga
    24361 ggttgacttc ttctcaattg gtacaaatga ccttatccag tacacaatgg cagcagaccg
    24421 catgaacgag caagtgtcat acctttacca gccatataac ccatcaatcc ttcgtttgat
    24481 taacaatgtt atcaaagcag ctcatgctga aggtaagtgg gctggtatgt gtggtgaaat
    24541 ggcaggtgac caacaggctg tgccgcttct tgttggtatg gggcttgatg aattttcaat
    24601 gtcagcaaca tctgtgcttc gcacacgtag cctgatgaaa aagcttgatt cagcgaaaat
    24661 ggcagagtat gctcatcgtg cactcacaga atgctcaact gctgaagagg ttcttgagct
    24721 tgccaaagag tatattacag aagcttaaat agaaataacg aggagctggt tttgtccggc
    24781 tcttttttac tagaaaaatg actaatcaga tccatatgaa agcttgcttt ataaagtagt
    24841 ttgatgtttc aagttttatc agaattttca gactcttcct gtagcgaatt gttgaaatat
    24901 gctaaaaaag tgatagaata atagtaccat tataaaagga gaaaaaagtt tggctaaaca
    24961 atataaaaat ttagtgaatg gtgagtggaa gctctctgaa aatgagatca agatctatgc
    25021 accagcaacc ggcgaggagt taggtagtgt accagctatg tctcgtgaag aggttgatca
    25081 ggtttatgcg tcagctcgcg ctgctcttgc agattggaga gcgctttctt atgttgagcg
    25141 tactgcttat ttgcacaagg ctgctgatat tttggtgcgt gatgctgaga agattggtgc
    25201 tgttctctca aaagaggttg caaagggtta taaggctgct gttagtgagg ttattcgtac
    25261 agcagaaatt attaactatg cagcagaaga aggccttcgt atggaaggcg aggtccttga
    25321 gggtggcagc tttgaggctg ctagtaagaa aaagattgcg atcgtacgtc gtgagccagt
    25381 gggacttgtg cttgcgattt cacccttcaa ttatccgatt aacctagcag gctcaaagat
    25441 tgctccagcc cttattgcag gaaatgtcgt ggttcttaag ccgccgacac aaggctctat
    25501 ttctggcttg ctcttagcag aggtatttgc agaagcaggt cttcctgctg gagtctttaa
    25561 taccatcact ggacgcggct cagttattgg tgattacatc gttgagcatg aggctgtaaa
    25621 ctttatcaac tttactggct caacgccaat tggagagcga attggtaaat tagccggcat
    25681 gcgtccgatt atgcttgagc ttggtggtaa ggattcagcg attgtcttag aagatgctga
    25741 tattgcctta gctgctaaaa acattgttgc aggtgccttt ggctactcag gtcaacgctg
    25801 tacagcagtt aagcgtgtgc ttgttatgga aagcgttgca gaccagctgg tagcagagat
    25861 taagggctta gttgagaaat tacttatcgg tatgccagag gacaatgctg acatcacacc
    25921 attgattgat accaaagcgg cagattttgt tgaaggtctg gttaatgatg cagcagacaa
    25981 gggagcacag gcgcttactg aaatcaagcg tgacggtaat ttaatttgtc ctatcttgtt
    26041 tgatagagta acaactgata tgcgcttggc ttgggaggag ccatttggtc cggtgctgcc
    26101 agtgattcgt gtaagctctg tagaagaggc aatcagcatt tcaaatcaat ctgaatacgg
    26161 tttgcaagcg tctatcttta cgactaattt tccacaggcc tttgctattg ctgagaagct
    26221 tgaggttggt acagtacaca ttaacaacaa aacccaacgt ggtacagata atttcccatt
    26281 cctaggggct aagaaatcag gagctggtgt tcaaggggtc aaatattcaa ttgaggcaat
    26341 gacaagtctc aaatcagtcg tatttgatat tcaataacaa aaaagctagg gtatcttagt
    26401 ttgaaagcag ttgcacattt gtgcggctgt tttatttgtg tctctagttt taacagctag
    26461 ctatgcaaga aggtgagttg tcccaacctc aaagatgaga tctaaatatt taatgatttt
    26521 ggggtcgtaa aaaagtttag agtgttttga tctccttaag atgtgagtgt acaaagtctc
    26581 gccaacagcc agcaggacta gccattgagg tcaaggaagc tgctaaaata gctgatggtt
    26641 caaaagcttg gtgaaaggct taatatctat cattgctatt ttgagggctt tccattataa
    26701 tatgaatact agagctactt gtcggtctgc ctcttgagct gtgagatagc tgttggattt
    26761 agttgtctcc ttgtccacaa aaggcttaga ggcaaaggct gtggctatgc ttcttgcttc
    26821 ttttagtgaa gtgtatgaga tcttatgaaa actcatatag gctttggtat ctttgcaaga
    26881 ggactaatgg cttgctttac ttgccttgat agagggctgg gattgagggg tgatgacctg
    26941 cggtggtcat ctctagagct ccttgcttct ttttttatgt agactaatgg tttagactgc
    27001 tagcttcctt gtttagaaag taggacatca tgttacccaa gagaaaatta attgatcaac
    27061 gtcttgatta tgccattatt tttcctgttt tttgtttgct aatatttggt ctggtatctg
    27121 tatatgtggc agcaagtcat gattttccgc aaagcctcgc cactgttatg cttcaacagg
    27181 ttctctggat ccttcttgga gctgtgattg cctttaccct aatgtttttt agcacagaga
    27241 ttctgtggaa attaacacct gtcttttatc ttttgggtgt gctattaatg gttctgccac
    27301 tcatcttttt tagccctcgg ctggtagctg ctacaggggc gaaaaattgg attacgattg
    27361 gctcaacgac cttgtttcaa ccatcagaat ttatgaaaat atcctacatt ctggcaatgt
    27421 cttggttaac ggtctggttt aagagaaagc aggagagaag tcggttttta gatgattgga
    27481 agctcttggg cttatacctt gtcttgacgt tgccggtcat ggtcctgcta gcactgcaaa
    27541 aggacttagg aacagctatg gtttttttag ccatcttagc tgggattatc ttaatttcag
    27601 gaatttcttg gtggcttatt ttaccagctt tggtactagt ctttttactg gtttcagctt
    27661 ttttctttgt ttttttgttg ccagagggaa aagaattcct tttaaaaatg ggaatggata
    27721 cctaccaatt gaatcgtatt tcagcttggc tgacaccgtt tgatttctca gataccattg
    27781 cctatcagca gacgcaaagt atgatttcga ttgggagtgg tggctttttt ggtaagggct
    27841 ttaatcagct tgagctgtca gtaccagtca gagaaagtga tatgattttt acagtgatcg
    27901 ctgaaaattt tggctttctt ggtgcagcta gcttactgat cttgtattta atactgattt
    27961 accgcatgct tagggtgacc tttgcatcga ataacctttt ttatacctac atttcaaccg
    28021 gctttatcat gatgatacta tttcatattt ttgaaaacat tggcgcagca gttggtctgc
    28081 tacctttgac cggtattccc cttcccttta tttctcaggg cggctcttcc ttgatttcaa
    28141 atctgattgg ggtcggcctg atcctatcaa tgaactatca gcacgtcctt gctcatgaaa
    28201 agcaaagcga gcatgagctt agcagaagct cacgttatgt ttaagaggca tgtttggtcc
    28261 ttgttcggtt agaatgagct gccaatcagc ccttttttat ttgcttaatc gctataaaaa
    28321 taaagaaaaa tatgttataa ttaaggttat gaattatcat gattatattt gggatttggg
    28381 cggcactctc ttggataact atgaaatttc tacccaggct tttattgaga cgctgcattt
    28441 ttttaagctg tctgcaagcc acgatgccgt ttatcaaagg cttaagaaat caacagcaac
    28501 cgccattcaa gtatttgctc ccaacgaacc gcaattttta caatattaca aagcgaatga
    28561 ggctaagaaa ttagccaatc ctatttggtg cctaggtgca aaggacattc taaagaggat
    28621 tgtggcatca ggctcgcgta attttttaat atcccatcgt gatcatcagg tcaatgattt
    28681 gctggagcag gctgggcttt tgggctattt taccgaggtt gttaccgcct caaatggctt
    28741 tgccagaaag cctaaccctg agagcttact ttatttgaag gaaaagtacc tgatcagcaa
    28801 gggcttagtg attggtgatc gcagacttga tatagaagca ggacaagcag caggctttga
    28861 caccctgctt gttgatggta gaaaaaacct attggagata gtagattaga tggttgaaga
    28921 aaataaacaa ttagaagaca aggctcaaga gtatgacgct agccagattc aggtcttaga
    28981 ggggttagaa gccgttcgca tgcgtcctgg aatgtatatt ggctcaactg ccaaggaagg
    29041 cttacatcac ctagtttggg agattgttga taattctatc gatgaagcct tggcaggctt
    29101 tgccagtcat attcaggttt ttattgaggc agataattcg attaccgtta ttgatgatgg
    29161 acgtggtatc ccagttgata ttcaagctaa gacaggccgg cctgctgtag agacagtttt
    29221 tacagttttg catgccggtg gaaaatttgg cggtggtggc tacaaggttt ctggaggact
    29281 tcatggtgtt ggctcctcgg ttgttaatgc cttatccaca cagcttgatg ttcgtgtcta
    29341 taaaaatggg catatccact atcaggagtt taggcgtggt gctgtagttg atgatttggc
    29401 tatcattgga acgactgatg ttacgggaac aacagtgcat ttcacacctg atccagagat
    29461 ctttacagaa acaacagaat ttgactacca ggtcctggca aagcgtattc aagagctggc
    29521 ctttcttaat cgtggcttaa aaatctcaat tacagataaa cgagctggtc ttgaaagaga
    29581 agagcatttc cattacgagg gtggtattgg ctcttatgtt gcctttttaa atgacaaaaa
    29641 ggacgtcatc ttcgatactc cgatttattc tgatggtgag ctggagggga taacagttga
    29701 ggtggcgatg cagtacacta caggttacca tgagactgtt atgagctttg ccaacaatat
    29761 tcacacacat gagggtggta cccatgagca gggctttaga acagctctga cgcgcgtgat
    29821 taatgactat gctaagaagg ctaagattct caaggaaaac gaggataatc tgacaggtga
    29881 ggacgtccgc gagggcttga ctgctgttat ttctgtcaag cacccaaatc cacaatttga
    29941 agggcaaaca aagacaaagt taggaaattc tgaggttgtt aagattacca atcgcttgtt
    30001 tagcgaagct cttcagcgct ttctactaga gaatccgcag gttgcccgta agattgttga
    30061 aaaggggatt ctagcctcta aggctcgcat tgctgccaag agagcgcgtg aagtaacccg
    30121 caaaaaatca ggcctagaga tttccaattt gccagggaag ctggctgact gctcctcaaa
    30181 tgatgctagt caaaatgagc tttttatcgt ggagggggat tcggctggtg gatcagcgaa
    30241 gtcaggtcgc aatcgtgagt ttcaggctat tctgcctatt cgtggtaaaa ttttaaacgt
    30301 tgaaaaagca acgatggata aaatccttgc taacgaagaa atcagaagcc tctttactgc
    30361 tatggggaca ggctttggag cggagtttga tgtttctaga gctcgctatc aaaagctggt
    30421 catcatgact gatgcagatg tcgatggagc tcatatcaga acgcttttgt taacgttgat
    30481 ttatcgcttc atgcgaccag tattagaggc tggctatgtt tacattgctc agccaccgat
    30541 ttatggtgtt aaggttggca gcgagattaa ggaatacatt caaccgggag tcaaccaaga
    30601 agaggagcta aaggctgctc ttgaaagaca tagcacagga cgctcaaggc cgactattca
    30661 acgctataag ggcctaggag agatggacga tcaccagctt tgggaaacaa caatggaccc
    30721 tgataatcgt ctaatggcac gtgtgaccgt agatgatgcg gcagaggctg atcggatttt
    30781 tgacatgctg atgggcgatc gtgttgagcc aaggcgtgaa tttattgagg aaaatgcggt
    30841 ctatagtacg cttgacattt agtcaaatat attttgaaaa gcacctaaaa gtatgttata
    30901 atcgtaacgt tatagtgtat ttttgataat ataataaaag gcgattcttg ctagttgttc
    30961 ctactgaacc ggcagttgat caatcgcatc taaataataa ggagattaag atgtcaagcg
    31021 gaattatctt gctgattgtg gccatagtct tactagtgat tattgcttat ttagtgggtg
    31081 ttattatacg caagcgtaat gacacattaa ttaccagtct agaagaacga aaacaagctt
    31141 tatttggcct tcctgttaat gacgaaatcg aggaagtcaa gtctcttcac ttgattggtc
    31201 aaagccagac ctcatttcgt gaatggaatc aaaagtgggt tgatttgacc ctaaatacct
    31261 ttaccgatat tgaaaagcat atctttgagg ctgagcactt aaatgacacc tttaatttca
    31321 ttcgtgccaa gcatgagatt aatagcgttg agagtcaatt gaatctcgtt gaagaggata
    31381 ttaccgctat tcgtgaagca cttggcatat taaaggagca ggaagaaaaa aacagcgcgc
    31441 gtgttactca tgcactagat ttgtacgaaa agttgcaggc ttccgttgct gaaaatgaag
    31501 ataatttcgg atcaacaatg gccgaaattg aaaagcaaat gaagaatatt gaagcagagt
    31561 tttcacaatt tgttgccctt aattcatcag gtgaccctgt tgaagcagcg gaggttttgg
    31621 ataaggctga ggagcatacg attgccttgg ggcaaattac agagcagatc cctgctattg
    31681 tagcaaagct tgaagatgat tttccggatc aattggacga tctggagaca ggctatcgtc
    31741 gtttgctgga ggaaaattat cacttcccag aaaaaaatat tgaagcccgc tttcaagaga
    31801 ttcgtgagtc tattcgtgcc aattcatcag agctggttac ccttgatttg gaccgagcta
    31861 gagatgaaaa tactcacatt caagagcgta tcgactcact gtatgagctc tttgagcgtg
    31921 agattgcagc ctacaaggtg gttgctaaaa atagcaaaat attaccaaga tacctggctc
    31981 acgccaagca caacaacgag cagttgaagc atgagattgc tcgtctatca cgtaagtata
    32041 tcttgagtga aaatgaaggc ttaaatatca aggcctttga caaagacctc aaagatatcg
    32101 aagacaatgt ccttgagatt gctgaagcct ttgatcagca ggaaaagcca ttttcagagc
    32161 tacagctgat tcttgatcgt agtatcaaga cgttggcttc tgtagagtct ggtcagatgg
    32221 acgtctttgc tgctgttaaa gacattgaaa agattgagtc acaggctcgc cagcacttag
    32281 aaatctacgt cacacagctt cacatgatta agcgttatat ggaaaagcgc aatttaccgg
    32341 gaattccaca ggattttctg agtaccttct ttaccactag ttcgcagcta gaagcattga
    32401 tggacgaact aagtagagga cgtatcaaca ttgaagcggt gtcccgtctg tctgaggtgg
    32461 caacagctgc tattgctaat ctagaagagc taacctacca agtggttcag catgctacct
    32521 tgacagagca gctgctccag tactctaacc gttatcgttc ctttgaagct ggcgtgcaaa
    32581 atagctttga gcatgccttg aaattgttcg aggtggacaa tgactatcag gcatcatttg
    32641 atgagatttc ctatgccttg gagacagtcg agccaggagt gacagagcgt tttgtcaatt
    32701 cctatgagaa gacacgtgaa cgtatccgct tctaatgtga caagggttga tactttatat
    32761 tacgaaaaag cttgaaaaag cagtccatgc tgggctatgc tttttcaagc tttttgaatg
    32821 gtcaggctat ggcctccttg agctataccc aaaaagctgg ttcaagccag tcagtagaga
    32881 tagacaaggc cttagtgcta ttgggctgtt gctacatgag atattttgta ataaaatcag
    32941 acgattatcc atttaattaa aaaaaaaaaa aaaacgaaac tgcggaggaa acctgacgag
    33001 taactattta tggctatcaa tcagcatgtt acactctttt tggaaggcct agcaatcact
    33061 gactgtgagg ttaaccaaag aaaataagat gttaaggaga atatcaatga aaataactaa
    33121 agcattgtgt gtagcaggtg ctgttgcagt cctagccttg gcaccaatca gctcaagtcc
    33181 tgcaccaaca cagactgtat ttgctgctac acgtggtact gaagagtact gtcataatgg
    33241 gtggtgcagt tttcttgatg aacatggtga gtggaacacg aaacgtgagg gcgaatctaa
    33301 tagtccccta cagcgaggtt catggtggga ttggatttct tattggtctg gttatatatg
    33361 gtattctgta tataactggt ttaggtaacc tctcaacgcc actgctacca tactgataaa
    33421 tcccttagac tattctaagg gatttttact gcaaaaagca catagggaca aggcaataca
    33481 agctccagcc tgttcttagc tccctatacc ggtaaggatc ataacactca gaactccggc
    33541 agatgattgc aggagctatt ggagagtgag gactagtgaa agagcctctg ccagagggat
    33601 ttgcccttag tctttgtttg ttcagcaggc ttattgtcag agggcttgtc tagtatagcc
    33661 ttgagattgg tttcctcttt ggtgatggca tgatcactat gaatgatcag agcaaaagga
    33721 gagacagctc ctttctcatc tacaatagtg gcagatagag cgttttgttg ggccaatttc
    33781 atatagtaca tttgataagc agagccgaat tcagaggata atttgaatga caaggggaaa
    33841 taagcctctt tgaggtgagg cagctgggct gtgatgtagc ctttagcctt ttcatgatca
    33901 acctctgtca agggaagcgc taagacaatc ctttcagcat aggtccctaa ataatagcgt
    33961 tgttggtcgg ggtcaaatcg gttttctcct gaagctccct ttaagagtct tgtatctaat
    34021 gaatccatac aatcctttca agcatgtgat actgtcatta tactattaac tgcgccaaat
    34081 accaatgata aagcatttac taggtatttg atcggctttt ggaagaagat gaaatcaaag
    34141 aaaaacagca tgaaaacaac tctcttattt catgaaatta gtttttaagt tgcttaagac
    34201 cctagtttgt ggtattatta acatgtaaaa tattaaaact cataaggaga gtattataat
    34261 gtcaattatt actgatgttt acgctcgcga agtccttgac tcacgcggta acccaacact
    34321 tgaagtggaa gtttatactg aatcaggtgc tttcggacgt ggtatggttc cttcaggagc
    34381 ttctactggt gagcatgaag cagtagaact tcgtgatggc gacaaatctc gttaccttgg
    34441 tcttggtact caaaaggcag ttgacaacgt taacaacatt atcgctgaag cgatcattgg
    34501 ttatgatgtt cgcgatcaac aagctattga cagagccatg atcgctcttg acggtactcc
    34561 aaacaaaggt aagcttggtg ctaatgctat tcttggtgtg tctatcgctg tagcgcgtgc
    34621 tgctgctgac taccttgagg tgccacttta cacttacctt ggaggattca atactaaggt
    34681 tcttccaact cctatgatga atattatcaa cggtggttct cactcagacg ctccaattgc
    34741 tttccaagag ttcatgatta tgccagttgg tgcacctacc ttcaaagaag gtcttcgttg
    34801 gggtgctgag gtattccatg ctcttaagaa aatccttaaa gcgcgtggac ttgttactgc
    34861 tgttggtgac gaaggtggat ttgctcctaa atttgaagga actgaagatg gtgtagaaac
    34921 aatccttaag gctatcgaag ctgctggcta tgaagctggt gaaaatggta tcatgattgg
    34981 ttttgactgt gcgtcatcag aattctacga taaagagcgc aaagtctacg actacactaa
    35041 gtttgaaggt gaaggcgctg ctgttcgtac atctgcagag caaattgact accttgaaga
    35101 attggttaac aaatacccaa ttatcacaat cgaagacggt atggacgaaa atgactggga
    35161 aggctggaaa gcacttactg agcgcctagg caaacgtgtt caattggttg gtgatgactt
    35221 cttcgttaca aacactgaat accttgctcg tggtatcaaa gaaggtgcag ctaactcaat
    35281 ccttatcaag gttaaccaaa tcggtacttt gactgaaacc tttgaagcta tcgaaatggc
    35341 taaggaagct ggctacactg ctgttgtatc acaccgctca ggtgaaactg aagattcaac
    35401 aatcgctgac atcgcagtgg caacaaacgc tggccaaatc aaaacaggtt cattgtcacg
    35461 tactgaccgt atcgctaaat acaaccaatt gcttcgcatc gaagatcaac ttggtgaagt
    35521 tgcacaatac aaagggatca aatcattcta caaccttaaa aaataatttg attttagatt
    35581 aaaaggttga caagccttga ttttaaagca ttctaggact gtcctagagt gcttttagtt
    35641 ttagcttcat gtcaactgta gtgggtgact gatagctaag cacgagagga gacgaaggtc
    35701 gccttctctt tttcaatcgg ataaggctag ggaatcccca aatgtcgatg aagggaattt
    35761 tagaaggttt ctggaagtcg tatatgattt gtttcccttt gcagtgtcta cacctaggag
    35821 actgatagtc cagtgtagcg ctgacttcga tatgagtatc gtgctggata gtcttattca
    35881 aggtgatatt ttgatctttg attccgatga gtagtgtggt atgatgaatc tgttccataa
    35941 gacactttct aatgatggtc tggtcgcttt tcatgataag ccttatggaa ctttttgggt
    36001 actcaaaaag ccctataatc ttcataatga atttacccat tacagaaatt atagagccaa
    36061 tatttagagg attttagcct attggtagat tgacagtttc ttaagattgt gttacaatgt
    36121 aacacaaaga aacgaggtaa acgactatga gtacagttac tatcagatta aatcaagaag
    36181 aagaaatatt tttcaaaagt tacgcccaac tcacagggca aagtttatca agtctattta
    36241 aaaaagccct tgagcgggat attgaagatg agtatgattt aaaaatctat catcaagcct
    36301 atgctgaata taaagcagac cctgagacaa ttagccatgc tgattttaag aaagagctag
    36361 gcttataaca tgtaccgtat agagtattct aaaaaggctc aaaagcagat taagaaagta
    36421 gataagcaaa ttcagaggtt gctatttgct tggattgata agtatttaga gggaacagat
    36481 aacccacgcg caaatggcaa aggtttgacc ggaaatcatg ctaatgagtg gcgttatcgt
    36541 attggtgatt ataggcttat ttgtgatatt caagatgata agatggttgt tttagcgctt
    36601 gagtttgggc atcgtaaaga tatttactaa cgttgaggaa gtaagatggt caaaaataat
    36661 gcaattggta gcaactggaa agatgtaaga gctgagttat tcagcaagga agaattttag
    36721 aaagtgatgc tcgtattgct attatggaca agtatagtta aaaagtgtgc gtttttaatc
    36781 tgtatgatga agtaattgat aaagtaacag gtcaaaaggc tatcattgtc tgtattgcta
    36841 ataaattggt agatgattgt tatttaatcg aaccgctaaa ccattcttac ttaccagatt
    36901 ggcgtgagat aaatcagtta attcgatata aaaattagca ccttatcggg tgctaattcc
    36961 ttgcctgctg aactcataat ttaatacctt ttttactacc ccatatgttt cccctaatta
    37021 tgtgtacttg ctagatataa ggttaattgg gatagaattt tgaataaagt tgttgtattt
    37081 tgtaatagtg attgatattg ggataacctt aaaaaaataa tttgatttta gattaaaagg
    37141 tttacaagct ttgattttaa agcattctag gactgtccta gaatgctttt agttttgata
    37201 agcacaatcc gctgttgact gtataaaccg tatatgatac aaaataagag cttgtagcag
    37261 tgaagccact aactctagtg ctgtgggctc aaccttgatt gatgaatccc ttgcttttaa
    37321 tgcgtttatg aagcagtggc gtatcagtct agctcgttgt ggaaagcaat taactagaga
    37381 agaattacta tcctcaatca atatgctgac agccgcaggg atttgtgagt ttgatttgct
    37441 gtggcagcgt cttgctccta aggggtgtca gcgtcccaaa tggagccatc agctggagag
    37501 gctctttgcg gatacaaagc cttgtctaca ggtcttgtct gagacttatc agcttgggat
    37561 tattgctaat caggcaaagg gtctaaaaga gcgcttagag aggtttggga ttagtcatta
    37621 ttttgccctt atgatatctt cttctgatgt ggggctacaa aagcctgatc ttgctctgtt
    37681 tcgctatgca cttgatcaag caggcgtatt agcgcgtgat gctgtttata ttggggatcg
    37741 tgttgacaat gatattattc ctgctaaggc attgggaatg agagctgtca ggattcatca
    37801 agggcttgct gcgtccagtc cagatgatag gctttatcct agtgatgtcc atattagcaa
    37861 acttagtgac ctgttagaat gcttttaacc agtctttagc ttgaactagc ttttctttgt
    37921 ggtctttctg ggtgaatggc agcaagcttt ggagtcatgt tatggctaga ccttggatct
    37981 aagggcgctg agcgtctcat atgatgaggc cgatcaagta gtctccttga caagtagatt
    38041 attgtttggt gcttataggt ggctttaggt gatgactggt tttgcctcaa ctaaggctcg
    38101 ctattgctat ctggggtatc ttctgacttt tttaatgtgc tcttatctgg ttggattaga
    38161 cctgctcctt gcttgaggaa agctgttttt aacgctgatg agtctgggaa atggtgagat
    38221 tggtgttggc ttttactagt ttttttgcgt ttacttgggc taactttata tgagaaaaaa
    38281 agaaaaatat ttattttatc tgttattttt gttacaataa gcgtgtaaac taagatgcat
    38341 taaaaaggag tttttatgtc gaataagaaa ttttttactt atgcttcatt attggcatta
    38401 atcgctgttc ctactgtggt tgaagaggtg actgcacagc cttcagctca gcttgtttat
    38461 gcagatgagc taaggctatc accaagtacc gactcatctc cagtaacaaa gaccgatgag
    38521 gctgatcagc cagttgctca atctgtttct gcgacagaac cagtagaggc tcttgttatt
    38581 gcggataaag aaagcgcttt aaatcctgct gttctagctg atgccgatgg aagtcagccg
    38641 attgcagtgg ttagagctgg tcaagagggt cagccttata ccgttactgg caaaatcatc
    38701 agtgctgtta atggctgggg tggtcatggc ttttatatcc aggacagtca gggatcaggt
    38761 ctttacattt atccaggaag tgctttgggg tacgtgactg gtgatgtggt gcagctgaca
    38821 ggaacactga ctacttacaa gggtgagctt cagcttaaaa cgattacaaa gcatcataag
    38881 attaatggcg aattaccaac acctattgct gaggtaacca ttccggagct agaaaaagca
    38941 agcccgtcta ccctggtgaa gctttcaaat gtgactgttg gagacatttc atcagataag
    39001 cacgaaacct cctcttttaa ggtcagcgat acagctggca atagtgttgc ggtgcgtctt
    39061 gataatcgta caggtgttaa gacctctgac ttactctcta aaattggcaa gggtgatgtg
    39121 attaatctga cagctattca ctcaaccttt gatgggaagc tccagctcaa gccctttagc
    39181 cttgagcaat ttgaggtagt aaagaaggtt gttcgagaag aagaggtgac tcctcttggt
    39241 cgagtggtta aaatcggcca aattcaaggt gccagccaca cctcaccgct cttgaatcaa
    39301 gctgtaacag taaaagaggt ggtggtgacc tatcttgatg atgcaactca tttctatgtg
    39361 caagatatta atggtgacaa cgataaggcg acctcagacg gtattcgtgt ctttgctcaa
    39421 aatgctcagg tgcaggctgg tgatgtgctg accatttccg gaacagtgga ggagttcttt
    39481 ggcaaaggct acgatgaccg taagcagacg gatctgacca ttacgcaaat caaggcatct
    39541 aaggtcacta aaacagggac tgctcaggta ccagctccgc ttgtgctagg taaggatcgt
    39601 gttgctccag ctaatatcat tgataatgat ggctttagtg tttttgatcc agaagaggac
    39661 gctattgatt tttgggaatc cttggaggga atgcttgttg ccgttgataa tgccaagatt
    39721 ttagggccga tgtctcataa ggaaatttat gtgttaccag ggtcatcaac tcgagtgctg
    39781 actaactcag gtggtatttt acttcctgag acaggctata atacagacct gattcctgtt
    39841 ctctttaaaa aaggaaagca aaccatcaaa gctggtgatt cctatcaggg acgacttgca
    39901 ggtccggtat catatagcta tggtaattat aaggtgtttg tcgatgacag cagtcgtatg
    39961 ccagtcttgg ttgatggtca gctgaagcct gaaaagacac acatcaagaa ggaccttagc
    40021 aagctaagca ttgcctcata caacattgaa aacttctcag caaacccatc atcaacaaaa
    40081 gacgagaagg taaggcgcat tgcagaatcc ttcatctatg acctaaatgc tcctgatatt
    40141 attggtctca tcgaggttca ggacaataat ggacctactg atgatggcac aacagatgca
    40201 acacaaagcg ctcagcgctt gattgatgcc atcaaggcct taggtggacc agcttatcaa
    40261 tatgtggata ttgctccgga aaataacgct gatggtgggc agccgggcag taatattcgg
    40321 acaggcttcc tgtatcagcc aggacgtgtc agcctttctg ataagcctag aggtggtgtt
    40381 aatgatgcgg tgaaatgggt aaatggtgag ctaagcttga gtgttggacg tattgaccca
    40441 acaaatcctg cttggaatag tgttagaaaa tcattggctg ctgagtttat tttccaaggc
    40501 cacaaggttg tggtggttgc caatcatttg aattccaaac gaggcgacaa ttcattatat
    40561 ggacgtgttc agccggtaac ctttaaatca gaggaaagac gtcatgtctt agcaaggctt
    40621 ttgagccaat ttactaagga aggtgctagt cagcaggcta atatcgttat gttgggtgac
    40681 tttaacgatt atgagtttac gaagaccatt aagctgattg aagaaggaga tatggcaaat
    40741 ttggtgagca ggcatgagct ttctgaccgt tattcttact tctatagagg aaataaccaa
    40801 acgcttgata acatgcttgt ttcacgcaat ttgcttggtc gctacgagtt tgacatggtt
    40861 catgtgaatt caccatttat ggaagcgcat ggacgtgctt ctgatcatga tccgttgctt
    40921 cttcagctct cctttggaaa agacaagcca gcagcaccat cagatcagcc aaagaaaaca
    40981 ccagcaccag ctgcgacaac tcaagcctct aaggcaggac gtgcacagct attgccaaaa
    41041 acaggtgata agacagcgct tatggtaagt attttaggct taacagctgt ctttagctcc
    41101 tttagcctgt ttaggaaatg tcaggaaagg aagtaaagga tttctttggg gtaggccagc
    41161 agctgagcgg ctactgcgtt ttgtctgctg gtgctatata ggtggttgaa gcgagcgaag
    41221 agaggtatgc ttcctaggat catagcacaa tatcttatgc ttataaacga acacaatgct
    41281 ccttatgagc attcaaaacc tatactcaaa aggaatataa cagctgagtt aagagggatt
    41341 gcttttgaca gattgtggta aaaaaaggga tcttgaggaa ttggctagtg atctagctgc
    41401 caaaatgcga tgtcttgttt gactattttt ccctattggg atataatgac aatagaaaaa
    41461 gggtagttgt ttgcgcaact accctgtgca gaaccgttta agacggtggc agaatgaaag
    41521 ttaaaaaata atcgtcgacc taccaaagtt cagacggtta ttttttattg tttaatatga
    41581 cgattgcaac gactaagctg attaaggtaa gtaagaaact accaaaagcc agcatgagtt
    41641 gaagggcctc gtaagtagac aataaaacgc tcctttcagt tggattttga tgcattgccc
    41701 ataggcatca ccacctttca gaaatcagag ccaccgtctt agcttttctg taaagaacat
    41761 tatatcataa tcacatgaga aagccgttag attttaaact gatcaggcgg ctttttggtg
    41821 ttttgctgtc ttttagtgga atcgcctaag ctttgctgta tagtatggga ttttatgctt
    41881 tttgtaaggg cttaggctgc tatggcaggg tccatgtcct ttgtcaatag cttagtttta
    41941 tggtacaatg taggcgttgc ctagcaaccc ttggtgctta gttccctttc accaagcata
    42001 ttacaaacgt ggcggagctg tttatgctct agtctgacgt caaaggagaa acacatgaca
    42061 agttttactg ttcgtgacta tgtttacatt gctctagtgg ctgcccttta tgtggttttg
    42121 acaatcactc cacctttgaa tgctatttcc tatggcatgt atcaatttcg ggttgccgag
    42181 atgatgaatt ttttggcttt ttaccataaa aagtatatca ttgcggtgac cttgggctgt
    42241 atgattgcta atttttatag ctttggcttg attgatgttt tggtgggtgg aggctcaacg
    42301 ctcatttttg ttagcttagg tgtcgcttta tttaagcaat accaagagga atatctctta
    42361 aatggcttgc tgaataaggc ctttgtttat ttctcactat tttttgcgac ttctatgatc
    42421 accgttgcga ttgagcttta cttctttgga gcaccatttt tcctaacttg gtttaccact
    42481 gctgtagggg aatttgcttc acttatcatt ggctctatga tcattgatcg cttatcaaaa
    42541 cgcattaatt tacgacaata atagtaacat gtagccttcc gtttttggga ggctttttat
    42601 gattttcttc tagctaggca atagcttatt tgctatgttt tgtgataaaa taagactatg
    42661 aaaaaacgca taagagaatt gactgatctg ttaaatcaat accgtcagga gtattacacc
    42721 aatgacgctc cttctgtatc tgatagtgag tatgataagc tttatcgtga gcttgtagag
    42781 ctggagcaga cctatccagc ctatatccta aaggacagcc ccacacagct ggtgggcagt
    42841 acgattttga caggatttca gaaatatcag caccagtatc cgctctttag tttgcaggat
    42901 gctttttcac gtgaagagct taacgccttt gatcagcgga tcaaatcagc ctttcctgag
    42961 gctgaatacc ttgctgagct aaaaattgat ggcttgtcca tttcgctggt ttatgaggct
    43021 ggtgttctaa aggttggagc gacacgtggc gatgggacta ttggcgagaa tatcactgaa
    43081 aacattaaga atattaagga tattcccaaa cggctaagtc aagcacttga tgtgacgata
    43141 cggggggagg cctatatgtc gcgtcaggcc tttaagacga tcaatgaaga gcgtcaggaa
    43201 aatggtgagc cagaatttgc caatccaaga aatgcagcgg caggaacctt gaggcagctg
    43261 gatactagga ttgttgccaa gcgacagcta gcaacctttt tgtatcagga ggtaggccta
    43321 gaaactgctg atagccagca aaagaccttg gagcgcttgg ccgatttagg cttttcggtc
    43381 aatagccact atctgctgtc ctcatcgatg aatgacattt gggactttat ccagagcatt
    43441 gaagctagta gagaagagct accttatgag attgatggtg tggtggtcaa ggttaatcag
    43501 ttggcgatcc aagaggaact tggctttacc gtcaaggcac cacgctgggc tattgcttat
    43561 aagtttccag cagaagaaaa ggaagctgag attgtatctg tggattggac ggttggccga
    43621 acaggtgtgg tcacaccaac agctaatttg acccctgtgc agctggcagg caccactgtc
    43681 agtcgagcga ccttgcataa tgttgattat atcgcagaaa aggatattcg cattggggat
    43741 acggtggtgg tgtataaggc tggagatatt attccagctg ttttgcgggt ggttgaggct
    43801 aagcgtaggg atcaggctcc aatgcccatt cctacagcct gtccttcctg ccagagtcag
    43861 ctggtgcatt ttgaggacga ggtagctttg cgttgcatta accccttgtg tccgagcttg
    43921 gttcaacgga gcttggagca ttttgccagt cgtcaggcga tgaatatcgc tggtcttggt
    43981 ccagcggttg ttgaaaagct ttattctgct ggcctggtgc atgatgtggc agatatttac
    44041 cgactaagct tggaggattt gctgacgcta gatggtatca aggaaaagtc ggctgaaaag
    44101 ctcttggcag ctattgaaca atcaaaggca aactcagctg aaaagctctt gtttggactt
    44161 ggtattcgtc atattggcgc aaaggctagt cgtctgatat tagaggctta cggtgattta
    44221 gaggcgctgt tagctgtaac cgctgaagag ctcgctcaga ttgacgggct tggtctagtg
    44281 atcggacaat ccctggtgca gtattttcag caagagcaag ccgctcagct gctagctgaa
    44341 ttaaaatcag ctggggttaa tctggcttat ttaggccaaa ggcctgatca acaggctgcg
    44401 ctgtttggtt taacggtggt attgacagga aaattagaaa agctaaaccg tacccaagcc
    44461 atggaaaagc tagagcagct tggtgctaag gtaacaggaa gcgtttctaa aaaaacagat
    44521 ttagtggttg ctggcagcga ggcaggctct aagctggcta aggcccagca gctgggtatc
    44581 agaattgaag atgaggattg gttgctcaat ctttagtgag gtaataacat gaaaaaacaa
    44641 atgagggctc gtctgattta caatccaacc tctggtcaag aaatcatgaa aaaaaacgtt
    44701 gcagaggtgc tggatatttt ggaaggcttt ggctatgaaa cctctgcctt tcaaacgaca
    44761 gcagctaagc actcagcctt aaaggaagca agaagggcag ctaaagcagg ctttgacctc
    44821 ttgattgctg ctggtggaga tggtacgatc aacgaagtag tcaatggcat tgctccccta
    44881 gagaaaagac ctaagatggc gattattcca gcaggaacca ccaatgattt tgctagggcc
    44941 ttaaaggtac caagaggcaa tcccgttgag gccgctaagc tgattggtaa aaatcaaacc
    45001 atccgcatgg atataggacg tgctaaaaag gatacttatt ttatcaacat ttcagccgca
    45061 ggaagcctga cagagctgac ctatagtgtc cctagtcagc tcaaaaccat gtttggctac
    45121 ctggcttatc tggctaaggg agtggagctc ttgcctcgag tgagtaatgt tccggtgaaa
    45181 atcacgcatg atcatggcat ttttgaggga gaggtatcaa tgatttttgc agccatcact
    45241 aattctgttg gtggctttga aaagattgcc ccagatgcta agctagatga tggcatgttt
    45301 acccttattt tgattaaaac agccaacctg tttgaaattg tgcacctgct gcggttgatc
    45361 attgacggtg gtaagcatgt tacggatcgc cgcgtcgaat acattaaaac cagtaaaatc
    45421 accattgagc cccaatcaga taagcgcatg atgattaatt tagatggtga atatggtggt
    45481 gatgcgccaa ttaccctaga aaacttaaaa aatcacatca ccttttttgc aaatactgat
    45541 ttgatttcag atgatgccct tgtcctagac caagaggagc tggaaatcga agaaatggtc
    45601 aagaaatttg cgcatgaggt agaggattta gagcagggat tggaggaata gggctagtta
    45661 tggataatgc agttattgtt cattatcata gttgcaaggg acattatttt caattaagtc
    45721 tatggcaatg gcgagatggt aagctgggca aggacgctta tttttcgagg tttgacagct
    45781 ttggagcagt tgcttatctc acttatccag caccttattt tttgagtcat gcttatgtga
    45841 ttgtaaagga tcagttttgg cagcatcaaa ccgttgattt tcggattgag cgtgattatg
    45901 gggttccaaa gactgaggtg tggcttgttg atggtgatcc tacggtttat tattcgagac
    45961 aggctgctgt ggctagtcga catgatggta gatgtgatgt gcatgccttt gatatggctg
    46021 tcaatagtca ggcctttgac aagcgctggg gctttagtgg ctggctaggc tttcgctatc
    46081 agcctgagga gacgtctttt cgtttgtggg ctccaacagc agaaaaggtt gagctcattc
    46141 tctatgcttc gactgatgag agagctagtg ttgccaaggt tttgcccatg cagcgtgggc
    46201 agcagtactc gccagatcat catgcagaaa acacatgtgg tgtgtgggac atcagcctaa
    46261 gaggtgatta taattaccat gcttattgct accgggttta ttatcgcagg cgtaccttta
    46321 gagacactag ggatccttat gcgatcgcaa cgacagcaaa tggcaaaagg tcaattgtca
    46381 ttgcaccgga gcatttaaga ccgcagggct tttcagtgaa gcagggtaag gaggctacct
    46441 ggcgcttaga caatcctaat caggcggtga tctatgaaat gcatgttcgc gacttttcaa
    46501 aatcagaaac ctcgggcgtt agcttggcta atcgtggcaa atttaagggg ctgattgaga
    46561 caggcacgcg caatgctttt ggagattcaa cctgctttga ttatgtcaag tcccttggca
    46621 ttacgcatat tcagctccag ccggtctttg accatcatca attctttgat gaaaatggag
    46681 attatgccta taattggggc tatgaccctg aaaattacaa tgttccagca gccagcttta
    46741 ccagtaatcc gcatgagcca gctacccgta tcctggaatt aaaggaggtc attcaggctt
    46801 atcatgatgc aggcatcaat gtgatcatgg acgtggtgta caatcatacc tactcatcaa
    46861 gagagtcagc ctttcagctg acggttccgg attattatta ccgtatgaat cctaatggct
    46921 cctttcaaaa tggctctggc tgtggcaatg aaacggctag tgaaaaggaa atgtatcgca
    46981 aatacatgct tgattcgatc ctatattgga ccaatgagtt taacattgat ggcttcaggt
    47041 ttgatctgat gggcttacac gatattgaca ccatgaatct tatccgacaa gagctagata
    47101 agattgaccc aaggatactt gtttttggtg agggctggga tatgggagtt ggtctggcag
    47161 ctgagcagaa ggctaaaaaa ggaaatgcca gccaaatgcc tggaatcggc tttattaatg
    47221 atgatcagcg taatgcagtt aagggggcag aggtctatgg gagcttagag aagggctttg
    47281 tatcaggtgc accgacagaa ggacttgtag ccaagtctat tttgggcagt gatgagctgg
    47341 tctcttattg tacgcctagt caggtgatca attatgttga agctcatgac aactataacc
    47401 tcaatgattt gctgtgggtt ttgaatccag aggacagcaa gcaggatcat gtcaaacggg
    47461 ttcagctagc ttcagctatg acgattctca tgcaagggat ttactttatg cagctgggtc
    47521 aggaattttt acgaacaaag ctttacccaa caggtcagga taaggagctg acacaggcag
    47581 accgagaaag ggcgatgaat tcctacaatg cacctgacaa tgtgaatcag gttgactgga
    47641 gacaggttag cttggagcgc gaaacggttg ctattatgaa aaaactaatc tatctgaaaa
    47701 ctaaaacagc tttgttttca tacccatcat ttgagcaaat cagacagcat gtttacattg
    47761 agcatgctgg tgaaaatacg ggcttcatta gctttacagt agaagatgaa agaaagtatc
    47821 gattgatttt ctctagtttt agaaaccgct tgcaatcatc tgctaatcat gttataattg
    47881 aaacaaatga taagcgcttt caagatagtg agtccatgct agatgagctg acagcgatga
    47941 tccttgacat cacacaatag cctgagtgtt ctcaggttat ttttgtttgt tgtcaaggat
    48001 aaaagggctg tagttacagt tagcagagac ctattaggac cttgcttatc atatcgctta
    48061 gcgccttgaa aaagggttta ggagtaggga aagaagaggt gatgggatgg ataatgactt
    48121 agcgctttat acctttggca caggtgagaa ttttcacata caggattatc taggtgttca
    48181 tcggattaac aatgacacag gcaccagcta tgtctttagg gtatgggcgc ccaatgcaga
    48241 ggctgtcagc ttgattggag attttactga ttggcagtcc aatccacttg agatgagccg
    48301 aaatgaggct ggcgtgtggg aggttaccac tagcttgccg caggaaggag atatttataa
    48361 gtattgggtt aggcgccaag gtggtcagct tgttgaaaaa attgatccag tggcctttct
    48421 atttgaagct agaccaggaa cgggtgctat tgtcaaaacc cttccagcca aaaaatggcg
    48481 tgatagctta tggatgggac ggcgaaagcg ttttggcttt aggcagcgtc cggttaatat
    48541 ctatgaggtt catgcccatt catggaaaaa agacgaaaac gcaaggccct atgactttag
    48601 caagctaaaa gaagagctca ttccctatct caagagcatg cactacactc atgttgagtt
    48661 tatgccggtc atggctcacc ccttagatat gagctggggc tatcagctga tgggctactt
    48721 tgcctttgag tcaacctttg gaagcccaga agcctttcag gattttgttg aggcctgtca
    48781 tcttaataat attggtgttt tgattgattg ggtgccggga cattttacac aaaatgatga
    48841 cgccttagct tattttgacg gtacagctac ctatgaatat caggatcacc atcgtgctca
    48901 taattatggc tgggggccct aaattttgat ttgggtaaaa ctcaggtaca gtcctttttg
    48961 atttcaagtg cccttttttg gctggaggct tatcatgttg acggcattcg agtagatgct
    49021 gttagcaata tgctttactt ggattatgat caaggccctt ggactccgaa tcaatacggt
    49081 ggcaaccaaa accttgaggg gatagccttt cttcaaaaat taaccacagt tatcaaggaa
    49141 aaacaccctg atgtgatgat gattgcagag gaggcgacct cagctacccc aataaccagc
    49201 cctgttgcag aagggggact aggctttgat tataagtgga atatgggctg gatgaatgat
    49261 attcttaggt tttacgaaga ggatccttat taccgaaaat acgatttcaa tctcttgacc
    49321 tttagcttta tgtattgctt taaggagcat tacattttac ccttttctca cgatgaggtt
    49381 gttcatggca aaaaaagcct catgcataaa atgtgggggg accgctacaa tcaatttgca
    49441 ggcctaagaa atctttacac ctatcaaatc tgccacccag gcaagaagct gctttttatg
    49501 ggatctgagt ttggacagtt tttggaatgg aaatacgatc atcaattaga gtggcaaaat
    49561 ttagaggacg agctcaatgc caaaatgcag catttcacag ccagcctaaa tcagctatat
    49621 aaggaccata gcatgctgtg gcaaaatgat gaaacctatg acggcattga tattattgat
    49681 gcagacaata aggacgaatc agtcttgtcg ttttgtcgtc aaaacaataa aggagagctc
    49741 ctgctttgtg tctttaacat gacacctgtt gaaagaccag gctttaccat aggtgtgccg
    49801 atagcaggtc tttatcaaga aattttcaat acagagcttg aggcctttgg aggtgtctgg
    49861 aaggagcaca atcccttaac caacacagta gccaagaaat ggaagactta tccgcagacc
    49921 ttgagcttta ccctgcctgc actaggagca agcatctgga aaatcaagcg tcgtcagaag
    49981 caataagcta ttcattgctt acttagctgt ttcaaccaaa agaagtcact acagtcatga
    50041 aaggataacg aaatgaagaa tggaatgtta gccctcatat tagcaggggg acaaggaact
    50101 cgcttaggaa aattgacaca gagcattgca aagcctgctg tgcaatttgg aggtcggtat
    50161 cgtatcattg attttgccct atccaattgt gctaactcag ggattcataa tgtgggggtt
    50221 atcacccagt accagcctct tgccttaaat aatcatattg gcaatggttc gtcatggggc
    50281 ttagatggta ttaattctgg cgctacgatt ttacagccct actctgcaac agagggaaat
    50341 cgctggtttc aaggaactag ccatgctatc tatcaaaata ttgattatat tgatagcatt
    50401 aaccctgaat atgtgctgat cctgtctggt gatcatattt acaaaatgga ctatgatgac
    50461 atgcttcaga cgcataaggc taatatggct agcttgactg ttgctgtgat tgatgttcct
    50521 ctaaaggaag ccagtcgatt tggcattatg aacacagata ccaatgaccg cattgtcgaa
    50581 tttgaagaaa agcctgccaa tccaaaatca accaaggctt caatgggtat ttatatcttt
    50641 aattggcagc gccttcggac catgctggtt gacgcagaaa aaaacaacat tgatatgtct
    50701 gactttggtc agcatgtgat tccgtcttac cttgagtctg gcgagcgtgt ctacacctat
    50761 aactttaaag gctactggaa ggacgtcgga acgattgagt ctctctggga agccaatatg
    50821 gaatacatcg gtgaggaaaa tgccctagac agtcgtgatc gttcttggaa gatttattct
    50881 aaaaaccata tcgctccacc aaactttatc acagaggacg ccgaggtcaa ggattctctg
    50941 gtagtagatg gcagctttat ctctggtaag gtcaaccatt ctatcttgtc taccaatgtg
    51001 caggtaagaa agggagccga ggttaaggat tcctttatca tgagcgatgt tatcattggt
    51061 gagggtgcaa ggattacacg agctattatt ggtgagggtg cagtcattgg tgatcatgtg
    51121 atcattgatg gcagcaagga cgttcaagtc gtaggctata atgaagtagt gggggtacca
    51181 aatgaagatt gataaatatt ctgccattct aggcagctca attggctttg ctgaaatgaa
    51241 ggggctaaca gacacaagac cattagccaa cctacccttt gatgggaaat accggctcat
    51301 tgattttcaa ttgtccaacc ttgccaatgc aggtgtccgt agcatctatg gtatttttcg
    51361 tgggcaaaat atccgctcag tgtttgatca tatcaggtca ggtcgtgaat gggggcttaa
    51421 ttccttacta agtcattatt tccttggctt ttataacacc aaggaggatt ctaaagaggc
    51481 tgacaaggac tattatcagc agattttgac ctatttaaag cgctcagggt cagatcagac
    51541 catttacatg agctgtgata ttctctgcaa tattgagctt gggcaggtta ttcatctgca
    51601 caatgccaac catcgcaaca ttacggttgt ctacaagaaa atgccgacca aggccatctc
    51661 taaggctaac gatattttag atattgacga gacagatact gttgttgaca ggcgaagtct
    51721 gtctgagggg caggaggttg aaaaaatgtc agcaggcatt tacatcgtca ataccccatg
    51781 gttaattgaa cagatggaaa aagaagccga aaaagaaaac cctcaaaagc tacgcttcct
    51841 cttacgtgat ttgattgtgt cagagggcgc tcttggcttt gaatatactg gctatcttgc
    51901 caatattcac tctgttaaat cttattttga tgccaatatg gacatgctgg atccgcataa
    51961 gttttattca ctattatatg ctaatcagaa ggtctacacg cgtgtcaaaa atgaagagtc
    52021 aacctatttt gatgcggctt ctgaggtgaa caatgcccaa tttgcttcag gaagcattgt
    52081 caagggctat gtcgagcact caattgtctc tcgcaattgt cgcattacct cacaggcacg
    52141 tgttacaaat agtattttat tgccaaaggc agtgattggt gagggtgctg tcattgatta
    52201 tgctatcatt gataaatccg taagggttgc accaggtgtt actattagag gaagcgctga
    52261 ggagccaata gttgttgcca aggggactga ggttgttgag gatatgataa aatgaagata
    52321 atgtttgttg cagcagaggg agctcccttt gctaagacag gtggcctagg cgatgtcatt
    52381 ggggcattgc ctaaatcact tgttaaaaat ggtcatgagg tgtctgtgat actgccttat
    52441 tatgacgtgg ttgatcaagc ctttggtcag caggttgagg acgtcttgta tttttatacg
    52501 caggttggct ggagacgcca atacgtgggc attaaaaagc ttgtcaagga taaggtgacc
    52561 ttttacttta ttgacaatca aggttatttc tttagaggca ggatctatgg tgattgggac
    52621 gacggtgagc gctttgccta tttccagctg gctgccatag aagcaatgga gaaaatcggg
    52681 gttattccag atattttgca tgtgcatgat taccataccg ctatgattcc tttcctattg
    52741 aaagaaaaat accattggat tcaggcctat caagcgattc ggacagtttt taccattcat
    52801 aatatcgcat ttcaagggca gtttgatcct ggcatgctag gcgatttgtt tgatgttggt
    52861 atagagcgct acgaggatgg caccctgcgt tggcatgatt gcttgaattg gatgaaagca
    52921 gcagtcctat atgcagatcg ggtaaccact gtctcaccct cttatgcgca tgaaattcag
    52981 acaccagcct ttggacaagg cttggatcaa gtcatgcgaa tggaggcagg caagctatca
    53041 ggcattgtga atggtattga cactgactta tttaacccag caagggatcc tcatttgcct
    53101 gcttcatttt cagcagaaga cctatcaggc aaggcggcta ctaaacaggc cttgcaggag
    53161 cggttaggat taccagtcag ggcagatgtt ccattgattg gtatggtttc gcgcttgacg
    53221 gatcaaaagg gctttcagct tgttcttgag gaattaccgc atatcttgca gcaggacgtt
    53281 cagcttgtct tgttaggaac aggtgaccct gattatgagg ctgccttttc atggtttgcc
    53341 aaggcctatc cagaaaaact gtctgctaat attacctttg atctgccatt agctcagcag
    53401 atttatgggg cctgtgatct ctttttaatg ccaagtgctt ttgagccctg cggactttcg
    53461 caaatgatgg ctatgagata tggcgcgata ccgattgtcc atgagatcgg cggcttgaag
    53521 gatactgttg cctcctacaa tgcttatgaa aagactggaa ctggttttgg ctttgatcag
    53581 ttttcaggat tttggttaac gcagacgctc ttgtttgccc ttgatattta ccataaccac
    53641 aaggaggatt ggcagactat tcaacaacat gccatgacca aggatttttc atgggataca
    53701 gccagtctgg cctaccttga tttatataaa agcttactat aacacagaaa aggaatggga
    53761 atgcacgtca caaaagaaca atttattcga gattttaaag ataccttaca tgaggaacaa
    53821 ttgatcaagg ttcctgccgc aacagctgct gagcttttca cctcattagc aaagcttatc
    53881 cgtaaatact atacagatac ttggattgaa aggaatcgtt ccttaaccga acagcagcaa
    53941 aaaattgcct attatttttc gatcgaattt ttaccaggaa gaatgctaga aacaaatctt
    54001 cttaatttag gcattcttga tacagttaaa gaagcctttg ctgacttggg aattgatttt
    54061 caagcagtga agcatgcaga gcacgacatg gctctaggca atggaggtct aggacgtttg
    54121 gcagctgcct ttatggattc gctagcgaca acaggctatc caggctttgg aaatgggctg
    54181 cgttatcgtt atgggctgtt taagcaacgg attgtgaatg gttatcaggt agaattacca
    54241 gattcttggt ttggctctat tggtaatgtc tgggagatca gaaaggatca tgacattgta
    54301 gacgtcaagc tctttgggaa tgtttaccta aaagccaatc aggacggtaa gctagcgcca
    54361 atctatgagg gagctcaggt tttgagagct gttccctacg atgttcctca gattggcttt
    54421 gaaaatgatg tgattaacaa tcttcgcctc tgggacgtag aaatcccaga agaacatgag
    54481 cttgattacc caaccatcga gtcaagacgg gcagtcaagg acattactgc cattttgtac
    54541 ccagacgaca gcagctatga aggcaaaaag cttagattga tccaagaata tttcatgacc
    54601 agcgcaggca tccaaaccat tatcaaatcc tatttaaagc agggcttgcc acttactgag
    54661 cttcatcaaa aggtatctgt tcatatcaat gatacccacc cagcagtagc tccagcagag
    54721 cttatgcggc tcttgattga cgactatggc ttagaatggg tagacgcctg ggcgacaacc
    54781 gtaaaaacca tgagctatac caatcatacg attttgtcag aagccttaga aaaatgggac
    54841 gcagagctct ttaagactgt gctgccccgc gtttatcaaa tcattttaga gattgatcat
    54901 cgctttgttg ctgaaatggc gcaaaagggt attgatcctc agatcattga aaacactaga
    54961 atcgttaagg acaaccagat ttatatggct aatcttgcca ttattggtgg ctattcggtc
    55021 aatggcgttg ccaagctaca tacagagttg ttaaagacag atacccttaa ggacttttat
    55081 gccttgtatc ctgaaaaatt caacaacaaa accaatggta tcgtgcaaag acgttggaca
    55141 cagattgctg cgccagagct atcagcagct attgaccgca cgattggcaa aggctggcgc
    55201 aaggatattc accagcttcg acaattgagt caatttacag aagatccagc tgtgctaaat
    55261 gatttttatc aggtaaaaca agcagctaag cagcgcctag ccaggtatat cctggaaaaa
    55321 acaggtcttg aggtttcaac agaggctatt tttgatgtgc aggtcaaacg cctacatgcc
    55381 tacaagcggc agctcctgaa cgtcctgcat attatgaagc tttaccttga tttgaaggct
    55441 aatccagatt tagatatggt gcctagagtc tttattttcg gcgcaaaggc tgcaccaggc
    55501 tatcattttg ccaagtcggt gatcaaaatc atcaatgagc tggctaatct cattaaccat
    55561 gataccagtc tcaaaggaaa gctaaaggtt gtttttcttg aaaattataa cgtgagtcta
    55621 gcagagctca ttatccctgc ggcagatatt tcagagcaga tttcactggc ctccaaggaa
    55681 gcctcaggaa catcaaacat gaaatttatg atgactggtg ctatcaccct agcgaccctt
    55741 gatggggcaa acattgaaat caaagacgag gtcggagagg aaaacattgt gatctttggt
    55801 atggataagg atcaggtcta tgaccactat gccaagcatg attattattc aagaggccta
    55861 tatgagagcg accctcagat taaagcagta gtcgacgctt ttgtcaatgg caccattcca
    55921 aatagtcaac acgaaggtat ggaaatctat gatgccctaa tcacgcataa tgatgaatac
    55981 ttcttgctag aagacttttc ttcctatgta aaagcacagg ctaagattga tcggctctac
    56041 cgccaaaagg atagatggtc aaaaatgtcg ctcatcaaca ttgcccattc tgacaagttt
    56101 acatcagatg ataccatcac ccagtatgcc aaggacattt ggcagctaaa acgctaatcc
    56161 atcaaggaag aaaaagcatt agttacctta gattgaagag agtgtctttt gagaccattt
    56221 tcttcaatct tttttgattg caaaagacct tgggaatcag atcagctgcc tgcctaatac
    56281 tttggcctat caaggtattt tggaatttgt taatcttttt gttataatag tggtgtgaag
    56341 ctatttttta aatgaaaaag ccaacacttc aagatggtgt taaagtaagg ttagtattag
    56401 tctaagaaag cgtaaccaca ttaaagaaag ctgttgacat tctcaatttt aaggaataga
    56461 ataacaaagt aaaaaatttt taaaaggagt attctattat gaatcctatt ttcgcattgg
    56521 ctcttgcctg ctttggtgta tcacttgccg aaggcttttt gatggctaat ctctttaaat
    56581 cagcgtcacg ccaaccagaa attatcggtc aattacgttc cttgatgatc ctaggtgttg
    56641 cctttattga aggtaccttc ttcgttaccc ttgttatggc cttcattcta aaataacagc
    56701 ctatttgata tagaaaagga gggtattaaa tggaagaagc taaagtaccg atggtagagc
    56761 ttggtccaat aacctttaat ttgaccctac ttgctgtttg tattgttact atcctactga
    56821 tatttggctt tgttttttgg gcaagtcgtc agatgacatt aaaaccaaaa ggcaagcaaa
    56881 ctgcgttaga atatttaatc agctttgtta atggtattgg ggaagagcat ttggatagtc
    56941 atcttcagaa gtcttattcg cttttacttt ttaccatttt tctttttgtg gcagttgcca
    57001 acaacttggg cttatttaca aagctagaaa caaccagtgg ctacaaccta tggacatcgc
    57061 caacagctaa tttggccttt gacctagccc tatctctgtt tgtgacgctt cttgttcata
    57121 tcgaaggcat tagacgtcgt ggttttggcg cttatttaaa acgctttgcg acaccttggc
    57181 caatgactcc gatgaaccta ttagaagaat ttaccaactt cctatcactt gctatcaggc
    57241 tgtttggtaa tatctttgca ggagaggttg tgacaggctt gattgttcag ctggccaatt
    57301 atcgcctgta ttggtggcca attgctttcc ttgttaatat agcatggaca gccttttcca
    57361 tatttatttc ctgcatacaa gcctttgtat ttacaaaatt aacagcaacg tatttaggaa
    57421 aaaaagttaa tgaatcagaa gaataagaag ggaggacaaa cgaatgtcag ttacaattgg
    57481 tgagctcatt gggaatttta ttctggtaac aggctctgtc atcgtcttgt tgctcttgat
    57541 taaagccttt gcttggggtg ctatcgaagc tgttttacag gcacgctcac agcaaatttc
    57601 acaggatatt gaccaagcag agcaggcgcg tctcaacgcc cagcagcttg aaaaggaagg
    57661 tcaagccaat ctagaagcca gcagatcaga ggctagtcag attgttgagg cagccaaaga
    57721 aactggtaaa gcacaggaga cacgcattgt agcagaggct acagaagagg cagatcgcct
    57781 aaaagcagca gcgttgacag atatcgaaca cagcaagtca gaggctattt cagccgttaa
    57841 gacagaaatg tcagatttga cagttttact agcagaaaaa attatgggag ccaatcttga
    57901 taaggcggct caaagccagc ttattgatcg ctatcttgat gatttaggag aggcttaatg
    57961 accaaaaaag aacaagctct tatcgagcaa tatgcaaaaa gtcttgtgca ggtctgtcag
    58021 gagcgagaca ctcttgaagc actgcaggct gatgtgcttg ccattttaga ggtttttaaa
    58081 gctactaatc ttgctaagac attgtcaagc ttagcggttc cacgtgctaa aaggcttgag
    58141 ctagtaaggc agcttcaagg agataatatc gtttatctga ataacttgct agaagttatg
    58201 ctgcaaaatg agcgtgaagc ttatttatat caagtgcttc taagggtttt atccgagctg
    58261 gctagtgtct caaatcaata tgacgtgaca gttacatcag cagttccttt aagtgaggag
    58321 caaaagcagc gtgtgcgtac agtggtttca aagagacttg cagtaaagac aggtcgctta
    58381 atcgaaaagg tagatccttc tttaattgga ggatttatga ttagcgtcaa taataaggta
    58441 attgatacaa gcattcgtcg tcaattacaa gcatttaaaa tgaatttaaa atagaaagtg
    58501 gtgtgacttt tggcaattaa tgcacaagaa attagcgctt taattaaaaa gcaaattgag
    58561 aacttccagc caaatttcga tgtcacagaa actggagttg ttacctatat tggtgatggg
    58621 attgcacgtg ctcgtggctt agacaatgcg atgagtggcg agcttcttga attttcaaat
    58681 ggtaccttcg gtatggctca aaacctagag tcaaacgatg ttggtatcat tattcttggt
    58741 gatttttcaa cgattcgtga gggtgatgaa gtcaaacgta ccggtaaaat tatggaagtg
    58801 ccagtcggtg aagctctcat tggacgtgtg gtcaatccac ttggtcagcc tgttgatggc
    58861 ttaggtgaca ttgagacaac tggctttagg cctgttgaaa ctccagctcc tggtgttatg
    58921 cagcgtaagt ctgtttttga gtccttacaa accggtctaa aggctattga tgctttggtt
    58981 ccgatcggtc gtggccagcg cgagctgatt atcggtgacc gtcagacagg taagacgtct
    59041 gtagccattg atgccatctt gaatcaaaag gggcaggaca tgatttgtat ctatgtcgct
    59101 attggtcaaa aggaatcaac agttcggaca caggttgaaa ccctacgtcg ttatggtgct
    59161 ttggattata ccattgttgt aacggcttct gcttcacagc catcaccctt gctgtttatt
    59221 gcaccttatg ctggtgttgc gatggcagaa gagtttatgt acaatggcaa gcacgttttg
    59281 attgtttatg atgacctgtc taagcaggcg gtagcttatc gtgaattgtc gctcttgctt
    59341 cgtcgcccac caggtcgtga ggcctatcca ggagatgttt tctacctgca tagccgcttg
    59401 cttgagcgct cagctaaggt gtctgatgac ttaggtggtg gctcaattac agccttacca
    59461 tttattgaga cgcaggctgg ggatatctct gcctacattg cgacaaacgt gatttcgatt
    59521 acagatggtc agattttctt gcaagaggat ctctttaact caggaatccg cccagctatt
    59581 gatgctggct cgtcagtatc tcgtgtcggt ggctctgcac agatcaaggc tatgaaaagg
    59641 gttgcaggga ctttgcgtct tgacctagcc tcttatcgtg agttagaagc ctttacacaa
    59701 tttggctcag atctagatgc agcaacgcaa gcaaaattaa atcgtggtcg tcgtactgtt
    59761 gaaatcctaa agcagccact gcacaagccc ttgcctgttg aaaagcaggt ggtcattttg
    59821 tacgctttga cgcatggatt tttagatgat gttcctgtag atgatatttt agcctttgaa
    59881 gaagcacttt atgactactt tgatgcgcat tatgatcact tatttgaaac aatccgtaca
    59941 accaaagacc ttccgcagga ggctgagctg gacgttgcta ttcaggcctt caaagcacag
    60001 tcaaacttta aataaaagag gggggtacta gtatggcagg ctctctaagt gaaattaagg
    60061 ctaaaatcat ttcaaccgaa aaaacaagca aaatcactag cgccatgcgt atggtttctt
    60121 ctgcaaagct tgttaaatct gagcaagcag ctcgtgattt tcaaatctat gcttcaaaga
    60181 ttcgtcagat tacaacagac ttactgaaat cagacctgac aacaggctca gataatccca
    60241 tgctggtgtc tcgtcctgtg aaaaagacag gctatattgt tattacctct gataaaggac
    60301 tggtcggtgg ttacaattca aaaatcttaa agtccattat ggacatgatt caggaatacc
    60361 atgccgctgg cgattatgag attatctcaa ttggcagcat cggctcagat ttttttaagg
    60421 ccagaggtat gaatgttgcc tttgagctgc gcggcctagc agatcagcca agctttgatc
    60481 aggtcggaag gattatctct cagtctgtag gtatgtttgt caatgagatt tttgatgagc
    60541 tgtacgtctg ctacaatcac catgtcaata gcttgacgag ccaggttcgg gttcagcgca
    60601 tgctgccgat ttctgatttg gttgccgagg aggccgcaga agaaggtgtc actggatttg
    60661 aattagagcc aaaccgtcat gtgattttgg agcagctgct gccgcaattt actgaaagct
    60721 taatttatgg tgcgattatt gatgcaaaaa cagcagagca tgctgctggc atgactgcaa
    60781 tgcagactgc cactgacaat gccaagcatg tgatcaatga tttgaccatc cagtacaatc
    60841 gtgcgcgtca ggcggccatt acacaagaaa ttacagaaat tgtagctggt gctaatgcac
    60901 ttgaataagc ttattgtatg ctgatagcgc tctagcagag acctattagc acttaatgtc
    60961 atcttcaaag ctagatgaca tttgggatta atgagctagg ggccttttac ccttagctac
    61021 tcgaatttag aaaaattcag cttaatcccc tactatcgaa tataaggaga aaaacatgag
    61081 ctcaggcaaa attgctcagg ttgttggtcc agttgtagac gttgtgtttg cgagtgggga
    61141 caaactacca gagattaata atgcgttgat agtttataaa gatggcgata aaaagcaaaa
    61201 aatcgttctc gaggttgccc tagagcttgg agacggtatg gtacgtacaa ttgctatgga
    61261 atcaaccgat gggcttacac gtggattaga ggttcttgat actggtcgtg ccattagtgt
    61321 accagttggt aaagagactc taggtcgtgt tttcaacgtt cttggtgaaa ccatcgacct
    61381 agaagcacca tttgcagatg atgttaatcg tgaaccgatc cataaaaaag caccagcctt
    61441 tgatgaattg tcaacatcat cagaaattct tgaaacaggt atcaaggtta ttgacctgct
    61501 tgccccttac ttaaagggtg gtaaggtcgg tcttttcggt ggtgccggag ttggtaaaac
    61561 cgttcttatc caagaattaa tccacaatat cgctcaagag catggtggga tctcggtatt
    61621 taccggtgtt ggtgagcgta cgcgtgaagg aaatgacctt tactgggaaa tgaaggaatc
    61681 aggcgttatt gaaaaaacag ccatggtttt tggtcagatg aatgaaccac caggagcccg
    61741 tatgcgtgtt gccttgaccg gcttgacaat tgctgaatat ttccgcgatg ttgaaggcca
    61801 agacgtcctg ctcttcattg acaatatttt ccgctttact caagcaggct cagaggtatc
    61861 agcccttcta ggtcgtatgc cttcagccgt tggttaccag ccaacacttg ccactgaaat
    61921 gggacaattg caagagcgta tcacctcaac gaaaaaaggc tctgttacct ctatccaagc
    61981 catctacgtg ccagctgatg actacactga tccggcgccg gcaacagcat ttgctcactt
    62041 ggattctaca actaaccttg agcgtaagct gacgcagatg gggatttacc cagcggttga
    62101 tccactggct tcaagttcac gcgcgctgtc accagaaatt gttggtgagg agcactatgc
    62161 agtagccaca gaggttcagc gtgtcttgca gcgctatcgt gaattgcagg atatcattgc
    62221 tatcttaggt atggacgagc tgtcagaaga ggaaaagaca ttggtaggac gtgcgcgtcg
    62281 gattcagttc ttcttatcgc aaaactttaa cgtcgcagaa cagtttacag gccttcctgg
    62341 ctcttatgtt ccagttgccg aaaccgttcg tggcttcaag gaaatcctag aaggaaagca
    62401 tgaccacctt ccagaagacg cctttcgtgc tgttggacca attgaggacg tgatcgaaaa
    62461 agctaagaaa atgggctttt agtgaggtga tgccatgaca caaatgactg ttcaggtggt
    62521 tacgccagat gggatcaaat atgatcatca tgctaagttc atctcagtaa cgacaccaga
    62581 tggtgagatg gggatcttac ctaaccacat caatgtgatt gctcctttac aggtgcatga
    62641 aatgaagatt cgtcgtgtca gtgaagacga tcgcgttgat tgggttgcta tcaatggtgg
    62701 gatcattgag atcaaagaca acgtggttac cattgttgca gattcagccg aacgtgatcg
    62761 tgatattgat gttagccgag cagagcgggc aaaattgcga gcagagcgtg acattgcaga
    62821 ggctgaaacc actcatgata ttgatgaggt gcggcgtgct aaggttgctt tgcgacgtgc
    62881 cttgaaccgc atcaatgtta gtaaaaaata gtaaaatgag tctaacctac caatttaacc
    62941 aagacagagc gagtagcgct gcttaggaaa gggtgtagat agactctttt atctttttat
    63001 agaaaaaata ccctcttt
//
LOCUS       DARYNN010000003        61154 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.003, whole genome shotgun sequence.
ACCESSION   DARYNN010000003 DARYNN010000000
VERSION     DARYNN010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 61154)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61154)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61154
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.003"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(272..1951)
                     /locus_tag="TVB59_000139"
     CDS             complement(272..1951)
                     /locus_tag="TVB59_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009090.1"
                     /translation="MTKKVASLVLIGLDSLILAGFYWIYLPPMNVMSLEFWFFVILAL
                     ILAMVSLFILSLFGLKKTVTSFFTQKSGRKDVTSGLSLKQLTGGIKWLGLALAVIIAG
                     LSLLLAVNTRMFRAKSYAHVIKVKDADFNKDFPDTDLSALALLDRDSAEKIGDTYLGT
                     IDKVSQFGISDEYRQITIGKLPYRVSPLEYKSFWKWLTNRKDGIGYYVKVNQTTGKAE
                     LVKLNQPMKYSHSEFMFRDTMRHLRFQYPMTIFSDPSFEVDDDGNPYYVATTYAPKFG
                     LSSQEPTGVILLDAVSGKSQYYELKDVPKWVDRVYSADNVLERVNDYYTYQKGYWNTV
                     FSQTDVKQTTDSYNYITIGSDIYLYTGITSATADSSNLGFILVNMRTREVTNYKLPSA
                     TEASAMKSAEGEVQEKKYTATAPTLVKLNDKAYYLISLKDGAGLIKSYALVDAEDYQQ
                     VTVNNDIQTLISQFTDKDTSSLSVSDTNDQKVKMITGQVEQLASQIISGTTVYYISSK
                     GQIYKIKASSETSDRLPFLKVGDQFKAQLADDNYLNHMTIESSSADQAITE"
     gene            complement(2126..7030)
                     /locus_tag="TVB59_000140"
     CDS             complement(2126..7030)
                     /locus_tag="TVB59_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEL1009091.1"
                     /translation="MEKKERFSLRKYKSGMVSVLIGILFLTGMGSVVAEEQGVSSAHV
                     SAGQHQESREVLSVSQASEGAAVNAQDIDSQSSKAEEKTEEAMATGLVSSEMEALTES
                     NQSVKQQEESRELPPVNMDTHRWIKTEGAWNRGYKGQGKVIAVIDTGIDASHHAMRIT
                     NPAAAKFTSKADIDQRKKAAGIQYGVWLSDKVVFAHNYVENNDKVKEIKDDPFEGLDD
                     LDFDVIVQQIDIRRNRPQSIEAPQETVIKLDDTSGGTIIDWQDTDDDSKYESHGMHVT
                     GIAAGNGLKAAAAGERFLGIAPEAQVMFMRVFTHDLMGTGDPLFIKAIEDAVALGADV
                     INLSLGSANGSQLNGNRALMAAIEKARQAGVSVVVAAGNERAFGSDHADPLVTNPDYG
                     LVGAPSAGRTPTSVASINNKVIIERLMTVEGLKDRADLNHGKAIYLESVDFKDIKTSL
                     GFDVPYSFVYVKALTKEGYQEREVSGKIVLVQRDPNRKYDDIIAEAKQYGAAGVLIFN
                     NEPGKANRTMRLSSKGMVLPSAFISHEFGMAMAALNGNGTGTLTFDAEVSKAISQKGN
                     EMNYFSNWGLTSDGYLKPDITAPGGDIYSTFNDDHYGSQSGTSMATPHIAGASLLVKQ
                     YLEALQPQLAKDKLADLVKNILMSNAQIHINPKTNTTTSPRQQGAGLLNIETAVTSGL
                     YLTGKDNYGSISLGNVTDQISFEVTIHNLSNQAKSLRYQTELLTDQVDTKEGRFALRS
                     RSLKTYQGEQVDVPAQGHKTITITLDASNFTEELSKQMPNGYYLEGFVRFVDSKDEHK
                     DNINIPFVGFKGAFENLPVVEASIYELKAQGKTGFYFDSSGLKDEIYVGNHFTGLVTV
                     GTDTNVSMTTIADNGLHTLGTFRNKDGKFVLERNAVGYPVLAISPNGDNNQDFAAFKG
                     VFLRKYQGLQARVYKGTDTDRKELLWTSPSALQGDKNFNSDIRFAKSTTLLETGFSGK
                     SLTGADLPDGKYHYVVSYYPDVVGAKRQEMVFEVIVDRQTPELGTASYNPVTHRFRPS
                     QWLDRGQAGVLRDSVFYLETKDDKPYTITINDGLKYVTVSDNKQFVERLADGSFVLPV
                     DQVALGDFYYMVEDFAGNVAIAKLGNHLPEKIGQAELALTLTDINAQHQLSYSDNLNM
                     TAADTGLVTNEAELLIISRNRPQSRLAKLGQTAVISPNDDGNKDFVAFKGLPHQVYQD
                     LKVTVFAQEDTAMTSPIWSSQPGASVANVDSTAWYGTRASGARVMSGHYRYVVSYLDA
                     NGMPQAEAYAVTVSHQKPVITPASFQADGATEVFRPGPSKGQSPIGIVREEVFYLVKK
                     DGRKFDLTVEDQLIRFKDNKVMIAQNADGTYTIPKVEGVAEADYYYLVEDEAGQIAYM
                     SLAALRAVGPDKGVVSVALALDVLENKKEPAFTYLIRDEQGKPIEQLDYFNSSANSLI
                     LPFGRYTVELLAYDNHLFELRSDNLVSFSLDADTRLASVAFEMTRPIVASVWLLFNQV
                     LPEGSRVSLKAANGQLISLAPSLYVPSAYGKTLRQGSYEVLVELPEGYQLIGQGGLEV
                     SHNGVIELTFEVIKAKQPQLEHQAGGLTHYTGSSITSSALTAQAVKKAQVLPSTGEQA
                     AVNLVLLGLLSLGAAGSCQRQKKY"
     gene            7383..8210
                     /locus_tag="TVB59_000141"
     CDS             7383..8210
                     /locus_tag="TVB59_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEL1009092.1"
                     /translation="MKLISWNIDSLNAALTGESPRALLSRAVLDTLVAQDADIIAIQE
                     TKLSAKGPTKKHLESLLGYFPNHLNVWRSSVEPARKGYAGTMFLYKKELNPIVTFPDI
                     GAPTTMDAEGRIITLEFNDFFVTQVYTPNAGDGLRRLEERQLWDQKYADYLAQLDAQK
                     PVLATGDYNVAHKEIDLANPASNHRSPGFTDEERLGFTNLLNRGFTDTFRFIHGDIPN
                     VYSWWAQRSKTSKLNNTGWRIDYWLTSNRLIDKVSRSEMISSGERQDHTPILLEIDL"
     gene            complement(8286..8639)
                     /locus_tag="TVB59_000142"
     CDS             complement(8286..8639)
                     /locus_tag="TVB59_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEL1009093.1"
                     /translation="MITIYQYPKCSTCQKALAELKTLVSEVDIIDIKANPPKAEQLKQ
                     WLEHSDYSLKSFFNTSGMRYRELGLKDKVNSLSVEEAAELLATDGMLIKRPILLQDNQ
                     VLQVGYRTAYKDLGL"
     gene            complement(8643..9155)
                     /locus_tag="TVB59_000143"
     CDS             complement(8643..9155)
                     /locus_tag="TVB59_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEL1009094.1"
                     /translation="MWGGQILPLYECVYQSPLGKISLVATDVALIGAWFEGQRYFQAG
                     IKVQPIWQEQHALLKRACLWLDAYFERKPYPMLDCLSPQGTDFQRAVWRELQTIRWGE
                     TLSYGELAKRLQCRSAQAVGGAIGRNPLSIFIPCHRVLAADGRLIGYAGGLEKKAWLL
                     RHEQISVNKE"
     gene            complement(9612..10166)
                     /locus_tag="TVB59_000144"
     CDS             complement(9612..10166)
                     /locus_tag="TVB59_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1009095.1"
                     /translation="MEIRLAFPNELSQIMTVINSAKSALAQSGSSQWQKADGYPAYQD
                     IAADVLQGQGYVALLEGQIVAYAAVIDGQEDAYDKIYDGRWQHNHHRYVTFHRVAVLS
                     DRTGQGIAQTFLQGLIEGQHGPDFRIDTHEHNQVMRHIIEKLGFVYCGKVPIDGERLA
                     YQKIKKSHERAAYQEISEDSRYSY"
     gene            10377..11006
                     /locus_tag="TVB59_000145"
     CDS             10377..11006
                     /locus_tag="TVB59_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEL1009096.1"
                     /translation="MIKEFCAENLTMLNQLTSQSVNRVELCDNLAVGGTTPSYGVIKE
                     ACDLLHDKQISVATMIRPRGGDFVYNDLELRAMEADILKAIEAGTDALVIGLLTKDNQ
                     LDTDAIEQLLPATQGLPLVFHMAFDLIARDQQIASLEQLIDYGFVRILLHGSSDTRSI
                     YENIDHIKQLVKAAQHRIEIMIGGGVTADNCQELSQLTGTAIVHGTKII"
     gene            11465..12550
                     /locus_tag="TVB59_000146"
     CDS             11465..12550
                     /locus_tag="TVB59_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009097.1"
                     /translation="MTTRYFYKLLLTMLTLALGGFSLSACHSKISKPYQVAIFDKDHV
                     RTFMEKVDSLVPVETISRTQHKLFERESFKQAKQGYFAKTREGNDLKVLLTHIDQASL
                     EEKVLHADGNDAYTSTTDGDYFYTTAVFADRIDCYKYDRHLKKQAHKSILNQDTINAS
                     NQFLVIDDALYLLVSAVDIKSQQPKTELWKMDKSFTITDRIDLDESTAYLRMVNVGRT
                     LYITQAADGILETGEPRPGNKVMTYDLDSGQKSYLMLHVNSPRAIYHHAKTNELIIEN
                     DQHYNPDFAWTIYQLDTGEERTIRFEELAGQETSSPYFMMTSSNYYFLFPKRLYRYDC
                     SNHQMTCINLDQYGVTHAHALIAKPTP"
     gene            12736..13947
                     /locus_tag="TVB59_000147"
     CDS             12736..13947
                     /locus_tag="TVB59_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL1009098.1"
                     /translation="MYESPEKIPYQLPLYDKYEGNNSLFRDNASPNFRADVKDITATL
                     VAVLSNGYPTGKSSFCKDYCPDEIRARQLTQLAIWYFTDGISEETLKSNYSLNDLEFQ
                     GLKYLIQAGKTAGTSNNRTLDIYISKDRNSKFQNLLGSTLVVKTPENKENCQCTKIYI
                     EENGKDGYYLYIYEDTNKNDKYDKNKDKLLQKKYIKNGKDGKPGLNGQRGPQGEPGKQ
                     GPQGPRGDKGETGEKGQDGKPGKQGDRGPAGPQGPRGDKGETGEKGDPGRNGKDGKPG
                     EKGDPGQQGIPGPKGDPGKDGEKGERGEQGPRGENPTPTPDPMPQPMPDPAPKPESKP
                     EPKPIPQPEVKPQPETKPQQPNKPSTITSQPSGKALPKTNDTGSLITVLGTGLLSLLG
                     LGFLTRRKRKQ"
     gene            14258..15349
                     /locus_tag="TVB59_000148"
     CDS             14258..15349
                     /locus_tag="TVB59_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL1009099.1"
                     /translation="MRKTMKKMLAASTVCIIMSGSFIGGAARVLAEQYYGYDDGTKDG
                     GDWPVFLYVTPTNHPERKTDKEHCVYCFNRLNSSPELWESQFKDPSKLGIKLPIYEKK
                     EGDESLLRAKSQKPSDNLTSKLVTVLSNGYPNKTLGNLSEDQSRRLTQLAIWHFTDGY
                     ATNHFKDGYHLNKDEDSELKKLIETAEKNFQTTAHTYSLNLYVTSSYNYSTGKFYQHL
                     LGSTLTPKLPNPNPGPKPPGGNNPHHLPGENGQTKYPEGESGEAGAPKKPEPKPEPKP
                     EPMPKPEPKPQPEPMPEPKPKPEPQPKPAPQPEVKPQKPTKPSNTTSQSSGKGLPRTN
                     EAGSLMTGLGTGLLSLLGLGFLTRRKRKD"
     gene            complement(15482..16600)
                     /locus_tag="TVB59_000149"
     CDS             complement(15482..16600)
                     /locus_tag="TVB59_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1009100.1"
                     /translation="MIPFIKALFIKIRRKKTSYITFILLPMLTTMLALSLSFTGGSQA
                     KIGILDKDKSQVSKQFVSQLKHNKKYQIYTRLEEKAIDQYLKAKTLEAVLTIEPGFGE
                     KVLKGDTQKIALRSIADSQITEWFKAQANYLLENYNIIGDAAAGNQEVFKKISAHNTK
                     LSYKVKEITLADRSQSKSVSSTTTGFLLILMLGSTSVLYGGILLDKSSQIYNRLVLSR
                     LSSLQYMLSYVCVGIVAFAIQIVIMLGLLRVANVSFYIPTAIVLLTFFLYSLLAIGFG
                     LMIGAVSKNAQQSSQLANLIVMPTSMLAGCLWPLSITPPYMQAIGKLLPQHWVLTIIS
                     TFQNGGNLGEAWPYFLALFVAAMTLMVLASVLMKPLHR"
     gene            complement(16597..17724)
                     /locus_tag="TVB59_000150"
     CDS             complement(16597..17724)
                     /locus_tag="TVB59_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1009101.1"
                     /translation="MILFHLIKKESLQIFRDRTALLMMVVFPILMILILSFAFKSSFN
                     TAATVPKLTVRYQLEGKETEYQKNFITFLKLLNKELHLEAKETKDIAKAKQKVSEGAL
                     TAALEVKSDQNIEVTTNSINQQNADLINMLVNIYVDNAKTYDSIANLYPEAISNIKKR
                     KIDYIASSSVQTSKGMSSADYYAISMFTMITFYSIMSAMNLVLSDRQQGVASRIYLTG
                     VSNSAILLGKLIGGMLATAVQLTILYVFTRFVLRVNWGTNDWQIIGVTASLVYLSVAI
                     GIGLATGIRNQSFLTVASNAVIPVFAFLGGSYIPLSTLNSALINQLSNISPIKWVNDS
                     LFYLIFGGQSNPIPVTLMVNLGIGTAFILFALVRMRKQVAA"
     gene            complement(17733..18656)
                     /locus_tag="TVB59_000151"
     CDS             complement(17733..18656)
                     /locus_tag="TVB59_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1009102.1"
                     /translation="MSFVELKDVVKVYRGGKKAIDHVSLTIEEGRIYGLLGPNGAGKS
                     TLINAILGLIPLNAGEVTVLQQSYKSIRKISSKIGYVPQDIAVYPDLTAYENVELFGS
                     LYGLKGSELKEQVLKSLEFVGLKSQASQFPSQFSGGMKRRLNIACALVHSPKLIIFDE
                     PTVGIDPQSRNHILESIRLLNEQGATVIYTTHYMEEVEALCDYIYIMDHGQVIEEGSQ
                     AELERRYESDFTKQIMVTVAADQAIDLSNKPNWRLMDNELEAVLLIEHEDIGSVVRQL
                     TDAHIAFSEIRHKHLNLEEIFLHLTGKKLRD"
     gene            complement(18679..19365)
                     /locus_tag="TVB59_000152"
     CDS             complement(18679..19365)
                     /locus_tag="TVB59_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin associated protein SagF"
                     /protein_id="HEL1009103.1"
                     /translation="MIIILALLSFLILVTLFLTSHKRRRLVRWHLRHIRAMSYQQWLD
                     LLLGLIQLGLVLVCLLFSDALALDGLLTFLGRVSFGWEIICYVLLYSIALVELTLLVL
                     VLLFDLMLKKDSRLLLGKMTWLAFKPDRAAASFLLLSLVTLVDAFCYLGLCLFLGKDS
                     VAGLTLVVLGYALVKACRYSGWLQQLLALCLFSVIGVWCVTAALLYGWLIGSLLLTLT
                     YLLISFKEQR"
     gene            complement(19362..20033)
                     /locus_tag="TVB59_000153"
     CDS             complement(19362..20033)
                     /locus_tag="TVB59_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEL1009104.1"
                     /translation="MPLYTQCLNLCFLMATFCPSIAMQAIFGQGRDSYSFNLIGFLRA
                     VLVYYALVLTGIYLLSPPIKAPLGHSDGRLLIIGFILSFVVLFVEVAFLHLSRCWQKK
                     EWLPLVLSFVGTTQKWPQIGYPLVLACCEEITYRLIWFNILWLQWRLPIALVLLITSL
                     CYALNHFLMGRSIFYAKILTGLIYGSIYYVSQSLWLVLLVHVGGNLWVEGLSHLQSMH
                     KKVVR"
     gene            complement(20008..21366)
                     /locus_tag="TVB59_000154"
     CDS             complement(20008..21366)
                     /locus_tag="TVB59_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcaO-like family protein"
                     /protein_id="HEL1009105.1"
                     /translation="MLHYYPSFNHILDKLKGLSGNRTGILNQSQVPICNHPHDVYLKS
                     VTGQMPDYHKQFIGELSQVSYHIIGYGSHYEEALIKYLGESIERYATVIAGELLSDRI
                     VYASYKELSQTDPVMPLEYLQVFTQEQIDRCHDLHMIMCDKMVTQDDVLGWVKCPMFF
                     EDKEMYVPAQMLCVGYKTNQAVGEKHIIPGFSTGTASHTTLEAAMCNSLIEYIQIDSM
                     MLSWHTKKPCPRVIIDDPEILALLEEARLGKDSLYEIIPIDMTVGEDNPLYTFGIILK
                     NKSNEGPYLLFGVQAGLDPKHTLLRGIMEASAISYSYYYNLFYNPTSTQNAESDSPLF
                     LDLDSNVFYYAHPKDQELKWKAFEPLISGEVRLSDLTNHAGKDKKEDLKTLLAYTKKV
                     SPNAVFLDITPPEASEKGWYVTRVLTPELLEMCIPAFPFANHPRMRQFGGVTNAFVHP
                     MP"
     gene            complement(21379..22443)
                     /locus_tag="TVB59_000155"
     CDS             complement(21379..22443)
                     /locus_tag="TVB59_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin associated protein SagC"
                     /protein_id="HEL1009106.1"
                     /translation="MKYQLNSNVRIVQFDDTFCFRKGLWDFNEAVLDIAQEPQALKEA
                     YYSIISDWFNGKVIDTDTYEKTLESDLFAKLSEVITALYYNDLLMLEDAYALEENIMK
                     VLTGNYHFIAESGQAKDTAPVLFISDSSYVNESAELLAKHLNLNLQVASDELKMLIQE
                     TDVTSRLDALEHHRNMKCLSEKLADYQSIVICQGRLNIMMLRHLNEISVALKKQLVLG
                     FVDGPFIHACTLNPPHSADFDSLERRVLARLQDHTLYQRFASQQLPPTQPVSSSYVPL
                     LNVLMNLVVSEAFIIAQTGSSKFEGRLLSVYLPTLEIQVQDILKMSNSQTQGALTKLR
                     YEDQQISTREIVKKLLQEES"
     gene            complement(22440..23390)
                     /locus_tag="TVB59_000156"
     CDS             complement(22440..23390)
                     /locus_tag="TVB59_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="HEL1009107.1"
                     /translation="MPFFSKEKQRSDNQSDLTREEARQLFEFNTNHLSLSTYHHQTVL
                     KTSKQLVAQHLMPDETDNLSQRFLMNYKANNNYLGFKTSVAEFFTDSAVTTFSNSDYF
                     EDRANTIALPKAKKVSAALSTCITNRRSHRQFIDEEMPLQDLADLLYYACGVSSQAII
                     KEGMTKTVALRNCASGGGLYPITLFFYARNVETLKDGFYEYLPYQHALRCHHLSDQED
                     IRAFAEYGPITAENCNVILIYVYQYIKNTRKYGNQATAYAFIEAGEIAQNVQLVSTAL
                     VYGSVDIGGYNKEYLQEKLGLDGLTQHVIHMTIIGNKESQ"
     gene            complement(23618..23782)
                     /locus_tag="TVB59_000157"
     CDS             complement(23618..23782)
                     /locus_tag="TVB59_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin S family TOMM toxin"
                     /protein_id="HEL1009108.1"
                     /translation="MLQFASNILATSVAETTQVAPGGCCCCCSCCCCVSASWGNTTIN
                     NNYGAAEPKA"
     gene            complement(24311..24568)
                     /locus_tag="TVB59_000158"
     CDS             complement(24311..24568)
                     /locus_tag="TVB59_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEL1009109.1"
                     /translation="MDPKKIARINELAKKKKTVGLTGPEKVEQAKLREEYIEGYRRSV
                     RHHIEGIKIVDEDGNDVTPEKLRQVQREKGLHGRSLDDPES"
     gene            complement(25105..27144)
                     /locus_tag="TVB59_000159"
     CDS             complement(25105..27144)
                     /locus_tag="TVB59_000159"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014712716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEL1009110.1"
                     /translation="MTKDLLVELGLEELPAYVVTPSEKQLVERMADFLKANRLSYDAI
                     EGFSTPRRLAVRVLGLADQQTDLTEDFKGPSKKIALDADGQFSKAAQGFVRGKGLTVD
                     DIEFREVKGEEYVYVTKHEAGKQAKDVLAAVPEVLASLTFPVSMHWANNSFDYIRPVH
                     SLIVLLDDEPLELDFLDIHSGRISRGHRFLGEETSITSADSYEADLRSQFVIASAKER
                     QEMIIAQIRAIEAEQKVQVDIDEDLLNEVLNLVEYPTAFMGSFDPKYLEIPEEVLVTS
                     MKNHQRYFVVRDQAGKLMPNFISVRNGNAKHLQNVIKGNEKVLVARLEDGEFFWREDQ
                     KLSIEDLVAKLAHVTFHEKIGSVAEHMERTKVIAAFLADQAGLSEAEKSAVARAAQIY
                     KFDLLTGMVGEFDELQGIMGEKYALLTGEAAAVATAIREHYLPNSAEGELPETKVGAV
                     LALADKLDTLLSFFSVGLIPSGSNDPYALRRATQGIVRILEHFGWSIPMDKLIDSLYE
                     LSFDSLTYQHKAEVLDFICARVDKMMGSAIPKDIREAVLASSSFVVPELLARAEALAA
                     ASQLDTYKPAVESLSRVFNLAKKAVDAVLIDASLFENDYERALAQAVDSLVLSGSAKE
                     QLAQVFALSPVIDDFFDHTMVMTEDEAIRRNRLALLAELVKKVETIAAFDRLNTK"
     gene            complement(27510..28421)
                     /gene="glyQ"
                     /locus_tag="TVB59_000160"
     CDS             complement(27510..28421)
                     /gene="glyQ"
                     /locus_tag="TVB59_000160"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEL1009111.1"
                     /translation="MSNKLTFQEIILTLQQYWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLQSLER
                     LGIDPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAE
                     VTYGLERLASYIQEVDSVYDIEWAPGVKYGEIFLQPEYEHSKYSFEVSNQDMLLENFE
                     IFEKEAERALAQGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRHLARSVA
                     KTFVAERKKLGFPLLDDASRVALLAED"
     gene            complement(28787..29320)
                     /locus_tag="TVB59_000161"
     CDS             complement(28787..29320)
                     /locus_tag="TVB59_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEL1009112.1"
                     /translation="MIILLLMLLMFAIRLVFLKKSIKNEKAILANGGKEFGAQNTKFL
                     TLLHIMIYVFAVTEALLKQIKFDGISFLGLLLMIFSIAVLYEVTRILGDIWTVKLMLA
                     KDHKYVDHWLFKTVKHPNYFLNIAPELVGIALLCHAQITAMLLFPCYIIVIYLRIREE
                     NRLLSEVIIPNGTRPKS"
     gene            complement(29587..29811)
                     /locus_tag="TVB59_000162"
                     /pseudo
     CDS             complement(29587..29811)
                     /locus_tag="TVB59_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515130.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(29841..30680)
                     /locus_tag="TVB59_000163"
     CDS             complement(29841..30680)
                     /locus_tag="TVB59_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEL1009113.1"
                     /translation="MIKTVTMANGLAIPVLGFGTFKAADGEEAYQSTLAAIKAGYRHI
                     DTAAIYHNEKSVGQAIRDSGVPREELFITTKLWNDAHSYDGAKAALAASLERLGLEYV
                     DLYLIHWPNPKALRDCWQAANAAAWSYMEEAVEAGLVRSIGVSNFMVHHLEALKQTAT
                     ITPAVNQIRLAPGCYQKETVDYCRRHHILLEAWGPLGQGEIFADDTMQALAKKYNKTV
                     AQLALAWSIAEGFIPLPKSVHKERIVENMAIFDCEISPEDSERIRCLPGMSAIPDPDT
                     KDF"
     gene            complement(30767..31915)
                     /gene="nagA"
                     /locus_tag="TVB59_000164"
     CDS             complement(30767..31915)
                     /gene="nagA"
                     /locus_tag="TVB59_000164"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEL1009114.1"
                     /translation="MTSYIKADCFYYPNEVKPAGYLELNNGTFGYWTATVDDQAEVID
                     YTGYQIAPGLVDTHIHGYAGADVMDNSAEGLHAISEGLLSTGVTSFLPTTLTSTFEHL
                     EQVSATVASVADQVKGAKIQGIYFEGPYFTEEYKGAQNPIYMKNPRLDEFAAWQKAAK
                     GLIKKIALAPERDGVEAFVSEVTKQGVTVALGHSNGTYTEAKKAVAAGASVWVHAYNG
                     MRGLTHREPGMVGAVYNIPGTVAELICDGHHVSPVACDILMQQKGHEHVALITDCMRA
                     GGSPDGDYMLGEFPVIVENGTARLKDSGNLAGSILKLKDGIKNVVAWGIASPAEAIHM
                     SSYVPAASVGIEDVCGQIKAGHAADFIVLDKDLELVATYLNGQKAFEA"
     gene            complement(32032..33673)
                     /locus_tag="TVB59_000165"
                     /pseudo
     CDS             complement(32032..33673)
                     /locus_tag="TVB59_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983536.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
     gene            33864..34610
                     /locus_tag="TVB59_000166"
     CDS             33864..34610
                     /locus_tag="TVB59_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009115.1"
                     /translation="MRKPTKETHYLIISLLTIAIAGGAYLIFSSLSPKPATITTQSKG
                     YELLTKAQALVKEAEDNPTKEAIAKAQKAINQLKKTQSKEELQARLTAISLKHNQEDV
                     AIKVLKAAEDNPSPELKEAAQKAISKLSDEAKKAALQARLDAIGLSKPSTAQPETATP
                     AAEKNIAPAPAAPQIKHTTPSSGGTTPAPNPKPSPKPNPQPSPSPAPENPEPTPSPNP
                     QPNPQPETNTPSPQPPATEQSENTAPAGQN"
     gene            complement(35216..36058)
                     /locus_tag="TVB59_000167"
     CDS             complement(35216..36058)
                     /locus_tag="TVB59_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL1009116.1"
                     /translation="MTWKIVSDSGCDIRALKSQSNHLRFERVPLTLQIGSDIFRDDDG
                     LDIDQMMETMYQSSKPATSSCPSPDAFLQAYRGADNVIAITITGTLSGSHNSARLAQN
                     DLLEENPNANIHVIDSLSAGGEMDLIVLELERLINQGLSFDEVVEKITAYQEKTRLVF
                     VLAKVDNLVKNGRLNKLIGKVIGLLNIRMVGQASKEGTLELLQKARGQKKAVSAVLEE
                     IQKAGYKGGRVFISHAKNPKICEQIAEKIRAIYPEAEIQTSPASGLCSFYAEAEGLLM
                     GYEV"
     gene            36190..36747
                     /locus_tag="TVB59_000168"
     CDS             36190..36747
                     /locus_tag="TVB59_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEL1009117.1"
                     /translation="MAGKPISKQSLQNLAHCNQESRRLTREAIEIALLSLLEKKPLGH
                     ITISELVARAGVSRNAFYRNYSSKEDILECLLTSVIRRIFRGLKAFDLKTQAYQAWLY
                     LFTEAKKEATLLSIIFNHHLQQLLTQMVTKRLRAYQKWQEKKLSHYALLFWSNAIVSV
                     LSNWISDDMVVPAEEMAAMGLPLLA"
     gene            complement(37158..37982)
                     /locus_tag="TVB59_000169"
     CDS             complement(37158..37982)
                     /locus_tag="TVB59_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL1009118.1"
                     /translation="MIQLIAIDLDGTLLDSKKHIPKENIKAIQAAAQEGIKVVLCTGR
                     PQSGTRPYFEQLGLSDKEEYLILNNGCSTYRSPSWELLHYQSLTFSAIEHLYQLSQPF
                     SDIYLTLTGERDYLVIDSKVPDMVQADGDLVFTKVKATNLSQLSNSSQIIFQAMYMGE
                     KAALDTFEALVREKLSASFSVVRSQETILEVMPECVTKASALKELTADLKLRPDQVMA
                     IGDAANDLEMLAYAGLGVAMGNADEAIKKVADKVSLSNDQAGVAHAINQFALTKGS"
     gene            complement(37987..38601)
                     /locus_tag="TVB59_000170"
     CDS             complement(37987..38601)
                     /locus_tag="TVB59_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimeric intracellular cation channel family
                     protein"
                     /protein_id="HEL1009119.1"
                     /translation="MTIDMWELLSIIGTIAFALSGAIVAMEEEFDVLGIFILGFVTAF
                     GGGAIRNTLIGLPIEALWGQRPEFACAFIAIILIMLFPKLVAKGWVRAAVLTDAIGLA
                     AFSVQGALHAVRLAQPLSAVIVAAVLTGAGGGVVRDVLAGRKPTVLRSEIYAGWSIIA
                     ALVLYFKLATSNVECYLLVVLLTVMRMIGNKRQWHLPKIKWKED"
     gene            complement(38762..39634)
                     /locus_tag="TVB59_000171"
     CDS             complement(38762..39634)
                     /locus_tag="TVB59_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEL1009120.1"
                     /translation="MKKVMMSLLILATATLGACQASHQSDQPKQEQKEPQAKKGRLFL
                     SNMNSAKSQQEVRAALSHQLKEANVNAFMAGVQEYNSLVGKTGLTGAFTYQKQPDYDV
                     VAIDELWSQKQGNFIGTNCRINTFMLLKDSMTIAPTSSDDTLLFMDEDAITTSQLFTQ
                     AETERFKQLFSRVKTEATKDIQVHAKHMQEHFSAVSFNGPAKMLAVVIHDQLDGDYLF
                     IGHVGVLVEYKSKYLFVEKLSFQEPYQAILFDQKQDCYQYLYHKYKTYQTKTSAEPFL
                     MENNKAVNLASYRS"
     gene            complement(39845..40330)
                     /locus_tag="TVB59_000172"
                     /pseudo
     CDS             complement(39845..40330)
                     /locus_tag="TVB59_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515109.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
     gene            complement(40333..40599)
                     /locus_tag="TVB59_000173"
                     /pseudo
     CDS             complement(40333..40599)
                     /locus_tag="TVB59_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003106440.1"
                     /note="catalyzes the reversible reaction of
                     dihydroxyacetone phosphate with glyceraldehyde 3-phosphate
                     to produce tagatose 1,6-bisphosphate; in Streptococcus
                     pyogenes there are two paralogs of tagatose-bisphosphate
                     aldolase, encoded by lacD1 and lacD2; expression of lacD1
                     is highly regulated by environmental conditions while
                     lacD2 specializes in an efficient utilization of
                     carbohydrate sources; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
     gene            complement(40601..41533)
                     /locus_tag="TVB59_000174"
     CDS             complement(40601..41533)
                     /locus_tag="TVB59_000174"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEL1009121.1"
                     /translation="MILTVTLNPSIDISYPLNRLTLDTVNRVDRTTKTAGGKGLNVTR
                     VLAEAGQSVVATGFIGGKLGDFVIHQLQEQGISNQFFKIKGETRNCIAVLHEGMQTEI
                     LEAGPYIDMDEAEGFLNHMSIIAKQFDVLTFSGSLPKGLAAHYYQDLITMARVYGSKV
                     VLDCSGAPLKAVLAGKDKPTVIKPNLEELEDLIGQPVTLDEERLISLLSQPLFEGIEW
                     IIVSLGAQGAFAKHHNRFYRVTIPKIEVVNPVGSGDATVAGIAWALAEGDDDETLLKK
                     ANVLGMLNAQETRTGHVNMAHFDELFDRIQVEEV"
     gene            complement(41543..42058)
                     /gene="lacB"
                     /locus_tag="TVB59_000175"
     CDS             complement(41543..42058)
                     /gene="lacB"
                     /locus_tag="TVB59_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEL1009122.1"
                     /translation="MKIAIGCDHIVTDEKMAVSDFLKSKGYEVIDCGTYDHTRTHYPI
                     FGKRVGEAVANGLADLGVCICGTGVGITNAVNKVPGIRSALVRDMTTALYAKEELNAN
                     VIGFGGKITGELLMCDIIEAFIKADYKETEENKKLIAKIAHLESHNANQEDPDFFTEF
                     LDKWDRGDYHD"
     gene            complement(42074..42499)
                     /gene="lacA"
                     /locus_tag="TVB59_000176"
     CDS             complement(42074..42499)
                     /gene="lacA"
                     /locus_tag="TVB59_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEL1009123.1"
                     /translation="MTIILGADAHGNDLKEAIKGFLQQEGFDVTDVTAIADDFVDNTL
                     AVARALKADEESLGIMIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNARMIT
                     MGAEIVGQELAKNIAKGFVTGHYDGGRHQIRVDMLNKMA"
     gene            42635..43417
                     /locus_tag="TVB59_000177"
     CDS             42635..43417
                     /locus_tag="TVB59_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEL1009124.1"
                     /translation="MLKRERLLTIMEKVNANGFITVTDIMESLRVSDMTARRNLDELA
                     RAGKLVRIRGGAQSISMPQKLERSNTEKLTVQIEAKKEIARYASQLINDGETIFIGPG
                     TTLECLAEALINRHIRIITNSLPVFTILNKSKTVDLILIGGEYRAITGAFVGSLASQT
                     ILSLKFAKAFISCNGIYKNDIATYSENEGVIQRLACDNAIEKYLLADNQKFNAYDFYS
                     FYHLDNIDAIITDSKISDSVKERYRQFAKLLIARPADNQVSS"
     gene            complement(43833..44384)
                     /locus_tag="TVB59_000178"
     CDS             complement(43833..44384)
                     /locus_tag="TVB59_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEL1009125.1"
                     /translation="MSVTSSMLTLILCMTILWLIGVRNKLERYRIVIEESKRNVDIAL
                     EKRYDTISEMLKIAKSYAKHEEKVFTELVKLRQGLSLEETNDVMRTQEQALNEVFAVG
                     EAYPEMRSSEQFLSLQNEIAKENAALAAAKRIVNSNISLFNQAVVAFPVSIVASLINI
                     KQMTFLDIDLDHKKSLDQLDYTI"
     gene            complement(44397..45347)
                     /locus_tag="TVB59_000179"
     CDS             complement(44397..45347)
                     /locus_tag="TVB59_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3137 domain-containing protein"
                     /protein_id="HEL1009126.1"
                     /translation="MNENTKRLTDPIVLEKSRAIEASPEHHQKLEQIKSEMSGNARKN
                     NLGWLAMVIGAIILYGMVDRSLALFLIIFVGGLVWPRLKTFKTANELSYVDHFLLPVL
                     QEALPDVKIDYYSGIELSLLKLATPSSRWYDSNCHIIFGDDMQTEFCNLYAYHEENED
                     DNWHRVTDFNGQVLLAKYHTAIKGYIRIVPTQKGFLGREKVHSGYKAKLKGEVQLEME
                     DIRFNETYNVYCTDELSARMLLNPYMLAVLDEWREEMPVAVYMNGDTVVVSFYSGQQL
                     LKTPSSRGAIEKLSLSSEYENIQDKLVKMYRLLDTLNHQL"
     gene            complement(46218..48449)
                     /locus_tag="TVB59_000180"
     CDS             complement(46218..48449)
                     /locus_tag="TVB59_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HEL1009127.1"
                     /translation="MVKETYLLEGMHCTSCALAIEQAVKQLPGVEGAAVDVTTEKLSV
                     SYSTDSLSSAELIQAVRKAGYRAELLDETNMRGQLERLEEQASNEWYRFLWSALFSLP
                     LLYLAMGPMLGLVLPVALAPQSHAISYGLVQLLLTLPVLFLNRQYYENGFKALIKKRP
                     NMDSLVTLATSFAFIYSSYSCFKIVAGAAQFAHQLYFESVVVILTLITLGSYLEGRTK
                     GRASQAIQKLMSLRVTDVRVIREGALQLIPLEQVTNEDICFIQPGERVAVDGLIVEGQ
                     STVDESMLTGESLPVDKVTGDSVFAGTINGQGALRVKPSRLGNDTLLSQIIELVEQAQ
                     QAKAPIAALADRVSGVFVPIVLSLSLLSFLFWLFVMRESFDFALTIAIAVLIIACPCA
                     LGLATPTAIMVGSGRAAEQGILFKGGDILEKAYQVRTIVFDKTGTLTEGQAQLQRIIP
                     LAASEKQGLQEVASLEQYSQHPLGEALVRVAQEKGYDLLAVTDFQSLVGLGVTGVIDQ
                     HRLAVGNSELMSQQGIAISAAQTYAEQAALKGQTVVYYAKDNQLCALLLIADRLKADS
                     KAAIRALQDLGLQTVMLTGDNALTAQAIANEVGIDQVFSQVLPAQKAQIIADLKASGQ
                     LVAMVGDGINDAPALTLADIGISIGSGTDIAIEAADVILMTSAVRDVVECLELSRQTI
                     RVVKQNLFWAFSYNSLMIPVAMGILHVFGGPLLSPMLAGFAMSLSSISVVLNALRLRH
                     KKW"
     gene            complement(48449..48883)
                     /locus_tag="TVB59_000181"
     CDS             complement(48449..48883)
                     /locus_tag="TVB59_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEL1009128.1"
                     /translation="MDTISDAEWEVMRVVWANGSMKSSEIIAILHEKHHWSDSTVKTL
                     IGRLVKKKALRADRQGRSYIYQSLLDQDRRQLAMLRERLDGMCQRHHSRLLLALLKDT
                     PMTLEDIQAFQLLLEAKKVGAVSHVRCDCVPGQCHCQKKERI"
     gene            49113..50150
                     /locus_tag="TVB59_000182"
     CDS             49113..50150
                     /locus_tag="TVB59_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEL1009129.1"
                     /translation="MIKEKTLTYLKRQLILLALLLTAIGSQTIVQASTRSWKSWFIEQ
                     YFWLKRDKSYYAEQDENTFYNYVKSAGEKSNQGFNLTQNEVNGTLKTEYRDNMQVHSW
                     NENSTNPSNQKVILYLHGGSYLNNPTSYHIDMLKTLSTSLDAKIVLPIYPKAPTYTYD
                     VAMPRLVSLYQDILKSTNNNANNITIMGDSAGGGLALGLALALKNEDIKQPKDIILLS
                     PWLDVTLSNPEIPNYEASDPILSAWGLRIVGDIWARRGENNTKHPYVSPIYGDTSNLA
                     PITMFVGTHEIFYPDITKFDGMLKQKGHKHQLFVGEKMNHVYPIYPIEEAKTAQYQII
                     DTIKKEYEPQK"
     gene            complement(50222..50572)
                     /gene="rbfA"
                     /locus_tag="TVB59_000183"
     CDS             complement(50222..50572)
                     /gene="rbfA"
                     /locus_tag="TVB59_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEL1009130.1"
                     /translation="MTNHRIDRVGMEIKREVNEILHKKVRDPRVQGVTITEVQMLGDL
                     SVAKVYYTIMSDLASDNQKAEIGLKKATGTIKRELGKQLTMYKIPDLVFEKDNSIAYG
                     NKIDQLLRELEKKQ"
     gene            complement(50762..53632)
                     /gene="infB"
                     /locus_tag="TVB59_000184"
     CDS             complement(50762..53632)
                     /gene="infB"
                     /locus_tag="TVB59_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEL1009131.1"
                     /translation="MSKKRLHEIAKEIGKSSKEVVERAKSLGLDVKSHASSVEEADAN
                     KIASSFSAGVTKNVQAGSAKDKQVAEQKAKAAKATTPQPAASKAAEKPAAATQEASQP
                     VAVKPKSRNFKAEREARAKEQVARRQAGQNRSNDRKSDYRQLGRSQGQQTERAGHKSQ
                     NQQRDRRFDNRPSSGNNRNDGHRQAGNRDKNRSFNANSRQQDTGRQGQTQAGAPKIDF
                     KARAAALKAEQNAEYARQRESRFREQEEAKRLEQQARQEAKAAALKAQTEDKKHREAS
                     AKATESVASMAAASVAKPVDKRRKKQNRPDKGHDRDHGLEDGQKKNKKSWNSQNQVRN
                     QKNSNWNNNKKNKKGKHHKNSNTAPKPVTERKFHELPKEFEYSEGMTVAEIAKRIKRE
                     PAEIVKKLFMMGVMATQNQSLDGDTIELLMVDYGIEAKAKVEVDEADIERFFTDDSYL
                     NPENIVERAPVVTIMGHVDHGKTTLLDTLRNSRVATGEAGGITQHIGAYQIEEAGKKI
                     TFLDTPGHAAFTSMRARGASVTDITILIVAADDGVMPQTIEAINHSKAAGVPIIVAIN
                     KIDKPGANPERVISELAEHGIISTAWGGECEFVEISAKFNKNIDELLETVLLVAEVEE
                     LKADPTVRAIGTVIEARLDKGKGAVATLLVQQGTLHVQDPIVVGNTFGRVRAMTNDLG
                     RRVKSAEPSTPVSITGLNETPMAGDHFAVYADEKAARAAGEERAKRALLKQRQNTQRV
                     SLDNLFDTLKAGEIKTVNVIIKADVQGSVEALAASLLKIDVEGVRVNVVHSAVGAINE
                     SDVTLAEASNAVIIGFNVRPTPQARQQADTDDVEIRLHSIIYKVIEEVEEAMKGKLDP
                     EYQEKMLGEAIIRETFKVSKVGTIGGFMVVNGKVTRDSSVRVIRDSVVIFDGKLASLK
                     HYKDDVKEIGNAQEGGLMIEGFNDIKVDDTIEAYVMEEITRK"
     gene            complement(53652..53954)
                     /locus_tag="TVB59_000185"
     CDS             complement(53652..53954)
                     /locus_tag="TVB59_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEL1009132.1"
                     /translation="MNSLNRLSHLIGLAQRAKKVISGEELVIKAIRHQEVNLVFLAND
                     AGPNITKKVTDKSNYYNVEVSTVFSALELSAALGKPRKVVAIADAGFSKKMRTLMK"
     gene            complement(53947..54243)
                     /locus_tag="TVB59_000186"
     CDS             complement(53947..54243)
                     /locus_tag="TVB59_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEL1009133.1"
                     /translation="MPKVKKIPLRKSLVSGEIIDKRDLLRIVKNKEGQIFIDPTGKQN
                     GRGAYIKLDNQEALMAKKKQVFNRSFSMEVPESFYDEVIAHVDHKVKRRELGLE"
     gene            complement(54259..55413)
                     /gene="nusA"
                     /locus_tag="TVB59_000187"
     CDS             complement(54259..55413)
                     /gene="nusA"
                     /locus_tag="TVB59_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEL1009134.1"
                     /translation="MSKEMLEAFRILEEEKHIDKADIIEAVTESLKSAYKRRYGQAES
                     CVIEFNDKTADFQVFTVREVVEEVFDSRLEISLNDALAISSAYELGDKIRFEESVSEF
                     GRVAAQSAKQTIMERMRRQMREITFNEYKQHEGEIMTGTVERFDQRFIYVNLGSLEAQ
                     LSHQDQIPGETFKSHDRIDVYVYKVENNPKGVNVFVSRSHPEFIKRIMEQEIPEVFDG
                     TVEIMSVSREAGDRTKVAVRSHNPNVDAIGTIVGRGGSNIKKVISKFHPKRYDAKTGL
                     EIPVEENIDVIQWVDDPAEFIYNAIAPAEVDMVLFDDDDLKRATVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEYERLEAEKEAAMTEAVATEELLTNEEV"
     gene            complement(55523..56005)
                     /gene="rimP"
                     /locus_tag="TVB59_000188"
     CDS             complement(55523..56005)
                     /gene="rimP"
                     /locus_tag="TVB59_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEL1009135.1"
                     /translation="MNIANTAIIDIVTQIVEPVIKAPYELVDIEYDKMGNDYVLSILV
                     DKASGITVEDTAELTELISPLLDTISPDPFPDQYMLEVSSPGLERPLKTAESLKAAVG
                     SYINVSLYRAIDKVKVFQGDLVAFDGDTLTIDYLDKTRHKTVEIPYQAVAKARLAVKL
                     "
     gene            complement(57386..57565)
                     /locus_tag="TVB59_000189"
     CDS             complement(57386..57565)
                     /locus_tag="TVB59_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEL1009136.1"
                     /translation="MLTYDEFKQAIDDGYITGDTVAIVRKNGQIFDYVLPHEEVRSWE
                     VSIEEIVEEVLRELE"
     gene            57804..58790
                     /locus_tag="TVB59_000190"
     CDS             57804..58790
                     /locus_tag="TVB59_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL1009137.1"
                     /translation="MSKKLRNSLARIVVAAFASFAVMAIPTYHHSTVLAKTVSVNQTY
                     GEYKDYYTVIGESNIDQSAFPKIYKTTERVYKGQGTSEKRVTVSDVVYNPLDGYKRST
                     GAYGVVTKDMIDMSKGYREKWETNPEPSGWFRFYNRADNEEISEKEYDSRRTKSYKVT
                     NNVPVVLTTLKGKQYNSHLFVRSHLFADSLGGKSIRKNAITGTQMQNVGTRKGGMQYI
                     EKKVLSHITKNPDVYVFYSAIPEYQGTELLARSVLVSALSSDGVINETVRVFNTADGF
                     NINYEKGGLLTESPVSEIDNIEDSTTDEIENSVDDSEEIVYNDTTTEEEEEN"
     gene            complement(58853..59662)
                     /locus_tag="TVB59_000191"
     CDS             complement(58853..59662)
                     /locus_tag="TVB59_000191"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009138.1"
                     /translation="MPLKVIDSLLDGGLEDNSADPIKKSTLDVYYRYLLDSNLTIPYN
                     RIAKYVYENEQSDEVNEILENKIKFIVTKFQGGSKDKDILIKNLDKIKNNYMLAQVQK
                     EFIVENSKITRDGLKQIRKSTDNLEKQSNRMEKNVRVAEKELKQFKKTKSQIYTDFVT
                     ILGVFSSFVFIMFGGFSALSTMIGTLSTTEVSIGKTLVISSILLGFLLILIYSMLSWI
                     SIIIDKPIPLNCCSCNGNKLKHIGNTFLNNGYFFFLLIICVLCFMLGNYFK"
     gene            complement(59653..60174)
                     /locus_tag="TVB59_000192"
     CDS             complement(59653..60174)
                     /locus_tag="TVB59_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015986726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4065 domain-containing protein"
                     /protein_id="HEL1009139.1"
                     /translation="MHALFVANYIIEYSNKKGYPINNLKLQKLLYFVNVRNILENGAP
                     LFEESMEKWKYGPVVPDVYHEYKRFGAFSISTDEMIMEYVEFSHSPFADLEITEYNPE
                     NVENTGLIENTVAALNNRDPFELVNITHRHTPWKKDEDRIMEGIQGIKYTIEEIKDYF
                     GNHPEEKLWVQCH"
     gene            complement(60327..>61154)
                     /locus_tag="TVB59_000193"
     CDS             complement(60327..>61154)
                     /locus_tag="TVB59_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL1009140.1"
                     /translation="ELLIQLIEQNDLQKWDAEALAKRKESQMISSQCREVIEFYINLA
                     NAGMGVDKDGAYGTQCADVPCYAAKHWFGVDLWGNAADLLDSASAQGWEVHRMPTDAN
                     PRAGAFFVMDAWFGGINYGHTGLVYVDSDGYTMQTIEQNIDGNADALYVGGPARFNTR
                     DFTNVAGWFYPPYQGDVAAQTVSTDPQTSDTIVETPKTGTFTLDVAEINIRRWPSLAS
                     EVVGSYKQGDTVNFDSEGYANGYYWISYVGGSGKRNYLAIGQTDKDGNRISLWGKLN"
BASE COUNT        17985 a        14367 c        11676 g        17126 t
ORIGIN      
        1 agaattttta atcaaaacta tcctgcaatc agctgtttag ccattttaaa aggcaaacaa
       61 aaaccatgcc acattgcaat gacatggttt tcttcaagaa aggagcgagc tttggtttgg
      121 tactttctac aactgatctc caatagcagc tgctcctcgt tagtccctga gccacaggtg
      181 actgagcttt cctgcggcta ctctgatagt accagctact cttacaactg cataaagcag
      241 tggctgccag ccaagctaaa gctaaacaat attactctgt tatagcttgg tctgctgacg
      301 agctctcaat ggtcatgtga ttgaggtagt tgtcatcagc cagctgagcc ttaaactggt
      361 ctccgacctt taggaaaggc agacggtcac tagtttcact gcttgccttg attttataaa
      421 tctgaccctt ggaggaaatg taataaaccg ttgttcctga gataatctgg ctggccaatt
      481 gctccacctg cccagtaatc atcttgacct tctgatcatt ggtgtctgac actgacagcg
      541 agcttgtgtc cttatctgtg aattgtgaga ttaaggtctg aatgtcatta ttcactgtta
      601 cctgctgata atcctctgca tcaaccaagg cataggattt tatcagacca gccccgtcct
      661 tcaatgagat aaggtaataa gccttgtcat ttaacttgac tagggttggt gcagttgcag
      721 tgtatttctt ctcttgaact tcgccctcgg ctgatttcat ggcagaggcc tctgttgcag
      781 aaggcagctt atagttagtg acctctctgg tacgcatgtt aaccaaaata aagccgagat
      841 ttgacgaatc agctgttgct gaggtgattc ctgtatagag gtaaatgtct gagccgatgg
      901 taatgtagtt atagctgtct gttgtttgct tgacatctgt ctggctaaag acagtgttcc
      961 aatagccctt ttgataggtg taatagtcat taaccctctc caaaacattg tcagcagaat
     1021 agacacgatc aacccatttt ggaacgtcct ttagctcata gtattgagac ttgccgctaa
     1081 ccgcgtctaa caggatcaca cccgtcggct cctgagagga caggccaaat tttggggcgt
     1141 aggttgttgc gacatagtaa gggttaccat cgtcatcaac ctcaaatgac gggtctgaaa
     1201 aaatggtcat cgggtactgg aagcgcaaat gcctcatggt gtctctaaac ataaattccg
     1261 aatgagaata cttcataggc tgatttaact tgactagctc tgccttacca gttgtctgat
     1321 tgaccttgac ataatagcca atgccgtcct tacgattggt tagccatttc cagaaggatt
     1381 tgtactccaa gggagaaaca cgataaggga gcttgccgat cgtaatctga cggtactcat
     1441 cagaaatacc aaactgcgat accttatcaa tggtcccaag ataagtatct ccaatctttt
     1501 cagccgaatc tcgatccagc aatgccaagg ctgacagatc agtgtctgga aaatccttgt
     1561 taaaatcagc gtcctttacc ttaatcacat gagcatagga cttagcacga aacattctag
     1621 tattaacagc taacagcaag gacaagccag caatgataac agcaagggca agaccaagcc
     1681 actttatgcc accggttaat tgcttgagtg aaagacctga ggtcacgtcc ttgcggccag
     1741 acttttgcgt gaaaaagctg gtcactgttt ttttcaaccc aaacaaggac aggataaaaa
     1801 gactcaccat cgccaagata agcgcaagaa tcacgaaaaa ccaaaattct aagctcatca
     1861 cgttcattgg cggcaaataa atccagtaaa agccagccag gatcaagctg tctaagccaa
     1921 tcagcaccaa agaagcaact ttttttgtca tactaatctc ctcgtcacac cctaaggcta
     1981 tcaggggtat tcaatatctt ctcaccgcta ttgtaccaca tttcccctca aaagatgaca
     2041 tctcagccag acatttttat cagctcttag agcacctcag ctagaatgat caatacagct
     2101 gacaggctac gctcatagag cttgcttagt acttcttttg acgctggcaa gagcctgctg
     2161 ctccaagact gagcaagcct agcaggacta gattgaccgc tgcttgctca cccgttgatg
     2221 gtaggacttg ggctttttta actgcttgtg ctgttagggc agagctagtg attgatgagc
     2281 cggtataatg agtcaagcct ccagcctgat gttctagctg aggctgctta gctttgataa
     2341 cctcaaaggt aagctcaatc acgccattat gtgatacctc tagacctcct tgaccgatta
     2401 gctgatagcc ctccggtagc tcaacgagga cctcatagct tccttgtcgc agtgttttac
     2461 cataggcact tggaacatag agagacggag ctagagaaat caactgacca tttgctgctt
     2521 tcaggctgac cctgctgcct tctggcaaga cttggttaaa caagagccaa acagaagcca
     2581 caataggcct tgtcatctca aaggcaactg aagcaagcct tgtatccgca tctagactaa
     2641 agctaaccaa gttgtcagac cttagctcaa acagatgatt atcataagcc aagagctcaa
     2701 cggtgtagcg tccaaatggc aatatcaagc tattagctga gctattgaaa tagtccaact
     2761 gctcgattgg cttgccctgc tcatcacgaa taagataagt aaaggctggc tcttttttgt
     2821 tctcaagcac atcaagtgcc aaggcaacgg acactactcc cttgtctggt cctacagctc
     2881 gcaaagcagc taagctcata taagcaatct gacctgcctc gtcttccact agataataat
     2941 aatctgcttc tgcaacgcct tcaaccttag gaatggtgta ggtgccgtct gcattttgag
     3001 caatcatcac cttattatcc ttgaatctga tcagctgatc ttcgacagtt agatcaaact
     3061 tgcgtccatc tttcttgaca aggtagaaga cctcttctct aacaatacct attggacttt
     3121 gtcccttgct tggtcccgga cgaaagacct cagtagcacc atcagcttgg aagctagctg
     3181 gcgtaatgac tggcttttga tggctaactg tcaccgcata ggcctctgct tgaggcatac
     3241 cattagcgtc tagataagaa acaacatagc gataatgtcc tgacatcacc ctagctcctg
     3301 aggctcttgt gccataccaa gcggtgctgt caacattagc cacgcttgca cctggttggc
     3361 tagaccagat tgggcttgtc atagctgtat cctcctgggc aaagaccgtt acctttagat
     3421 cttgatatac ttgatgtggc aagcccttga atgccacaaa atccttgttt ccatcatcat
     3481 tcggcgagat gacagcagtt tgacctaatt tagccaaacg actctgtggt ctattgcggc
     3541 taataatgag aagctctgct tcatttgtca ccagtcctgt atctgcagca gtcatgttga
     3601 ggttatcact gtagctcagc tgatgctgag cattaatatc agttagggtc aatgccagct
     3661 cagcctgacc gattttttct ggcaagtgat ttcccagctt agcaatggca acattgcctg
     3721 caaaatcctc gaccatgtaa taaaaatcac caagcgccac ctgatcaact ggcaggacaa
     3781 aagagccatc tgctaagcgc tcaacaaact gcttattgtc tgatacggtc acatacttta
     3841 agccatcatt aatggtaatc gtataaggct tgtcatcctt tgtttccaag taaaaaacac
     3901 tatctcgaag aacaccagcc tgaccgcgat caagccactg agacggtctg aagcgatggg
     3961 tcacagggtt atagcttgct gttcctagct ccggcgtttg acgatccaca atcacctcaa
     4021 agaccatttc ttgacgtttc gctcctacca catctggata ataagaaacc acataatggt
     4081 atttgccatc tggtaggtca gctccggtca gcgatttacc actaaagcct gtttctaaca
     4141 gcgttgttga cttggcaaag cgaatatcac tgttaaagtt tttatcccct tgaagggctg
     4201 atgggctcgt ccagagcaac tccttacggt ctgtatctgt tcccttatag accctggctt
     4261 gcaggccttg gtatttacgt aagaacaccc ctttgaaggc agcaaagtct tgattgttgt
     4321 cgccatttgg agagatagcc aacacaggat agccaactgc atttcgctcc aacacaaatt
     4381 taccgtcttt attacgaaag gttcctagtg tgtgcaagcc attgtcagca atagtagtca
     4441 tagagacatt ggtatctgta ccaacagtca ccagcccagt aaaatgattg ccgacataaa
     4501 tctcgtcctt tagccctgag ctgtcaaaat aaaagccagt ttttccttga gcctttagct
     4561 cataaataga ggcttcaaca acaggtaggt tttcaaaggc tcccttaaag ccaacaaatg
     4621 gaatgttgat gttatccttg tgctcgtcct tgctatccac aaagcgaaca aagccctcta
     4681 gataatagcc atttggcatt tgcttagaga gttcctctgt aaagtttgag gcatctaggg
     4741 taatggtaat ggtcttgtgt ccttgagcag gtacgtcaac ctgttctccc tgataggttt
     4801 tcagagatct tgaacgtaag gcaaaacgtc cttccttagt atccacctga tcagtcaaca
     4861 attctgtctg gtagcgcagc gacttagcct gattagacaa gttatggatt gtcacctcaa
     4921 agcttatctg atcagtcaca tttccaagag aaatactgcc atagttgtct ttacctgtca
     4981 ggtacagacc actggttacc gcggtctcta tattcaagag ccctgctccc tgctggcgtg
     5041 gcgatgtggt ggtattggtc ttagggttga tgtggatctg agcattactc atcagtatat
     5101 ttttgaccag atctgctagc ttatccttgg caagctgtgg ttgaagcgct tctagatatt
     5161 gcttgaccaa aaggcttgcc cctgcaatgt gtggggttgc catactagtt cctgactggc
     5221 tgccatagtg atcatcgttg aaggtcgagt aaatatctcc acctggagca gtgatgtcag
     5281 gcttcaaata gccatctgag gtcaagcccc agttagagaa atagttcatc tcatttccct
     5341 tttggctaat ggccttagag acctcagcat caaaggtcag agtgcctgtt ccattgccat
     5401 ttaaagcagc cattgccatg ccaaattcat gagagataaa ggcagatggc agcaccatcc
     5461 cctttgaact cagacgcatg gtgcggttag ccttgcctgg ctcattgtta aaaatcaaga
     5521 ccccagctgc cccgtactgc ttggcctctg ctataatatc gtcgtatttc cgattaggat
     5581 cacgctgcac caagacaatc ttgccactca cttcgcgttc ttggtagcct tcttttgtca
     5641 aagctttgac ataaacaaat gagtatggta catcaaagcc aagactagtc ttaatgtcct
     5701 tgaaatcaac agattccaaa tagatagcct ttccatgatt taagtcagcc ctatctttca
     5761 agccctccac cgtcatcaga cgctctataa tcactttgtt attaatagac gcaactgagg
     5821 taggagtccg gcctgctgat ggagccccca ctaagccata atcaggattt gtcaccaacg
     5881 ggtctgcatg atctgaccca aaggcacgct cattacctgc agcaacgacc acagagacac
     5941 cagcctgcct tgccttttcg atagctgcca tcagggcacg attcccattc aattgagacc
     6001 cattggccga gcccagactt aaattaatca catcagcgcc caatgccaca gcatcttcga
     6061 tggctttaat aaataagggg tccccagttc ccatcaaatc atgggtaaaa acccgcataa
     6121 acatgacctg agcctcagga gcaatgccta aaaagcgttc gccagctgct gccgccttga
     6181 gcccatttcc agctgcaatg cctgtcacat gcatgccatg cgattcatat ttgctgtcat
     6241 catctgtatc ttgccagtca atgatagttc ctcctgatgt gtcatcaagc ttgatgaccg
     6301 tttcctgagg tgcctctatt gactgcggac ggttcctcct aatatcaatc tgctgcacaa
     6361 tcacatcaaa atccaagtcg tcaaggccct caaacggatc gtcctttatc tcctttacct
     6421 tatcattgtt ttccacatag ttgtgggcaa agactacctt atcgcttagc cagacaccgt
     6481 actgaatgcc tgctgctttt ttgcgctggt caatatctgc ctttgatgta aacttagcag
     6541 ctgctggatt tgtaatgcgc atggcatggt gactagcgtc aataccagta tcaataacag
     6601 caataacctt accttgaccc ttatagcctc tattccaagc tccttctgtt tttatccagc
     6661 ggtgagtatc catatttact ggaggtagct cgcgcgattc ttcttgctgc ttgactgatt
     6721 ggttagattc cgttagcgct tccatttcgg aagaaactaa tccagtcgcc attgcctcct
     6781 ctgtcttttc ctctgcttta cttgactggc tgtcgatgtc ctgagcatta acagcagctc
     6841 cctcactagc ctgagagaca gacaatacct cccttgattc ttgatgttgt cctgctgaca
     6901 cgtgagctga gctaactccc tgctcctcag ccacaactga tcccatccct gtcagaaaaa
     6961 ggattccgat caacacagaa accattcctg atttatattt cctcagtgag aagcgttctt
     7021 ttttctccac ttgatgtcct cctagattta ttaaaaaagg ttattttaaa caaatgattc
     7081 atttatgttt taatcaataa tgtctaagct atttaaccat tttttaatca caaaagcaat
     7141 aagactagaa gctctcagtt tatgtcattt tttaatcatt caactcactg aaatgaggcc
     7201 tctcagaacc tgtctcatca acagataagg ctaaactcag ccgctagact tcaaaaatgt
     7261 cacaccattt ttagacatta cctgtcctca tacctataac agaaccaagc ttccacagtc
     7321 gccttggcct tatttttttg ttacaatata ggttaagatt atcatttaga aagcgaagaa
     7381 aaatgaaact catctcatgg aacattgatt ctttaaatgc tgcgctcact ggtgaatctc
     7441 ctagagccct cttatcacgc gctgtacttg atactctcgt ggcacaggac gctgatatta
     7501 ttgcaattca agagacaaag ctatctgcca aaggccctac caaaaagcac cttgagagct
     7561 tgcttggcta ctttcctaat catctcaatg tttggcgttc atctgttgag cccgccagaa
     7621 aaggctatgc cggaaccatg ttcctctata aaaaagagct caatcccatt gtcacattcc
     7681 cagatatcgg agctcctacc actatggacg ctgaagggcg tatcatcacc ctagaattta
     7741 acgatttctt tgtcacacag gtctacaccc caaatgccgg tgatgggctt agacgcttgg
     7801 aagagcgcca gctctgggac caaaaatatg ccgactacct agcccagctc gatgcccaaa
     7861 agcctgtttt ggctactggt gattacaacg ttgcccacaa ggaaatcgac ctggctaacc
     7921 cagctagcaa ccaccgctct ccgggcttta cagatgagga gcggcttggc tttacgaacc
     7981 tgcttaaccg agggtttaca gatacctttc gctttattca tggcgatatt ccaaacgttt
     8041 atagctggtg ggcacagcgc agcaagacca gtaaattgaa caataccggc tggagaattg
     8101 attactggct cacgtcaaat cggttgattg ataaggttag tcgctcagag atgatttcct
     8161 caggagaacg tcaggatcac acaccgattt tattagaaat tgatctatag actagaagca
     8221 ttcggacaaa tcaacccaga cattaaaaaa aaatggctct gcaagagaac cgttttttta
     8281 atcgcttaaa gacctagatc cttataggct gttcgatacc ctacctgcaa gacctgatta
     8341 tcctgtaaga ggatcggccg cttaatcagc atgccatctg ttgccaaaag ctccgctgcc
     8401 tcctcaacgc tcagtgaatt aaccttatct ttaagcccaa gctcacgata acgcatacca
     8461 ctggtattga aaaagctttt gaggctataa tctgaatgct ctagccattg tttcagctgc
     8521 tcagctttag ggggattggc cttaatatca atgatatcaa cctcagaaac cagggtcttt
     8581 agctcagcaa gggctttttg acaggtacta cactttgggt attggtaaat ggtaatcatt
     8641 agctactcct tattaacact aatttgctcg tgcctgagca accaggcctt cttttcaagt
     8701 cctccagcat agccaatcaa gcgaccatca gcagccagta cacgatgaca gggaataaaa
     8761 atacttaaag gattacgtcc tatggcacca ccaacagcct gagccgaacg acactgcagg
     8821 cgcttggcaa gctcaccata gctcaaggtc tctccccatc ttatcgtctg caattctcgc
     8881 cagacagctc gctgaaaatc agtaccctgt ggagataagc aatcaagcat gggatagggc
     8941 ttcctctcaa agtaagcgtc aagccacaaa caggctcttt ttaacagggc atgctgctcc
     9001 tgccagatgg gctgcacttt aatcccagcc tgaaaatacc tttgaccttc aaaccaggct
     9061 cctatcaaag caacatcagt cgcaaccaag gatatttttc ctaagggcga ttgatacaca
     9121 cactcgtaca atggcaagat ctgacctccc cacataatag cttattccct tgactattta
     9181 ttataagaaa aagcctagct aaaggcaaga aggagccctc tgacaccaca acaaacgcat
     9241 gaaaaaacaa tagcggctct ttcaatgctg ccatacaatc gttagtgtca aaagtcgctt
     9301 actatacagc tgcccccctt gaaaaacgaa gctggaaaga cacaacatgc taaagctgtt
     9361 tcacgcgctg gtgcctgatt agatgttctt ctaattaaag gccaatgttc tgattaaaaa
     9421 gtcatttcat gcgctgatac ctactcaaat aaaaacacat agcgtggggc tagaccaatc
     9481 cctcacaagt catcaatagt tcgtctatga gctacacttt atcacattgg gataggcaga
     9541 catatttgcc ggctcagttg tacttgcctg atagctaacc aaaagcccga taagcttttt
     9601 ccgatcctat atcaatagct gtagcggcta tcctcgctaa tctcctgata agcggctctt
     9661 tcatggcttt tcttaatttt ttgataggct aagcgctcgc catcaattgg taccttgcca
     9721 cagtaaacaa agcctaactt ttcaatgata tgccgcatga cctgattatg ctcatgagta
     9781 tctatccgaa aatctggtcc atgctgcccc tcaatgagcc cttgcaaaaa ggtctgagca
     9841 attccctgac cagtcctatc actcagcacc gccacacgat gaaaggtcac ataacggtgg
     9901 tgattatgct gccacctgcc atcataaatc ttgtcgtagg cgtcctcttg gccatcaata
     9961 acagccgcat aagcaacaat ctgcccctca agcaaagcca catagccctg cccttgcaac
    10021 acatcagcag caatatcctg ataagcagga tacccatctg ctttctgcca ttggctggag
    10081 cctgattggg ctaaggcaga cttagctgaa ttgatcactg tcatgatctg actaagctca
    10141 ttaggaaaag caagtctaat ctccatcgtt cacactcaca atctattctg atttgatgat
    10201 gctatgctac cgcaaaaagc cttacacctt gtcactctgc tagggacacc tcatagcggt
    10261 atgcctgctt ctcatctcag ctgagtatag cacaatagtc atcatttgac aaaaagcctc
    10321 ttcaaggatt gccagcaatc atgctataat aaagtaaatc acaaaggaga accattatga
    10381 ttaaagaatt ttgtgctgaa aacctaacca tgctaaacca attgaccagc cagtcggtca
    10441 atcgtgttga gctctgcgac aatcttgcag tcggtggcac cacaccctct tatggtgtca
    10501 tcaaggaagc ctgcgacctc ctacatgaca agcagattag tgtcgcaaca atgatccgcc
    10561 caagaggagg tgattttgtc tataacgacc ttgaattgcg tgctatggaa gcagatatct
    10621 taaaggctat cgaagcagga actgatgcct tggtcatagg cttactcact aaggacaacc
    10681 agcttgacac cgatgctatc gaacagctcc taccagctac acaaggactc cctctggttt
    10741 ttcacatggc ctttgacctg attgctcgcg accaacaaat cgcaagccta gagcagctca
    10801 ttgactatgg ctttgtacga atcctgcttc atggctcaag cgataccaga tccatctatg
    10861 aaaacattga ccatatcaag cagttagtca aggctgctca gcaccgaatc gaaatcatga
    10921 ttggtggagg tgtcacagct gataactgcc aagagctaag tcaactaaca ggaacagcta
    10981 ttgtgcatgg cacaaaaatc atctaactat cagctcaaat aaaggaaaag tcactcccta
    11041 caaggaggta aataatagca gcccttctcg ttgaaggcca tacctgagcc cttagactag
    11101 gctcctagca aactaatagt ataggacctt cgctgccttt acatcaaaaa ggctgccgtc
    11161 cagaaaaaga gaaagccaca cattgataga aaaccatagc tggctctact actatcagta
    11221 tctatcatca gcttctgagc tgcctaaaag tttcggtgat cattaacaag tacagactat
    11281 ttgtttctaa attagatcat aaaacagaca attataggaa gcgacaagtg aatcattatt
    11341 cattttttat tgattactat gatactataa gtaaggatag cgctttcttt ttgtctttgc
    11401 tttgcctgac tattaggctc tagatttatt ttttaccata ctaatataag aatcggaata
    11461 aataatgaca acaaggtatt tttataagct attgctaacg atgttgacac tagcattagg
    11521 aggattttcc ctatctgctt gccactccaa gattagtaag ccctatcaag tcgctatttt
    11581 tgacaaggat catgttagga cctttatgga aaaagttgac agtctggtgc ctgttgagac
    11641 catctctcga acacagcaca agctatttga gcgagaaagc tttaagcagg ccaagcaagg
    11701 gtattttgca aagacaagag aaggaaatga cctcaaggtt ctgttaactc acattgatca
    11761 agcaagccta gaagaaaaag tccttcatgc tgatggcaat gacgcctaca cctctacaac
    11821 tgatggtgat tacttttaca caacagctgt ctttgccgat cgtattgact gctacaagta
    11881 tgaccgccac ttgaaaaaac aggctcacaa gtctattcta aatcaagaca ccattaatgc
    11941 cagcaatcag tttctggtga ttgatgacgc tctgtacctg cttgtcagcg ctgtagacat
    12001 caagagtcag cagcccaaaa ctgagctatg gaaaatggac aaatccttta ctatcactga
    12061 tcggatagat ctggacgaaa gcactgccta tctgcgcatg gtcaacgtcg gacgaaccct
    12121 ttacattacc caggctgctg atggcatttt agaaactgga gaacctagac ctggtaacaa
    12181 ggtgatgacc tatgacttag atagcggtca aaagtcctat ctcatgcttc atgtcaatag
    12241 tcctagagcc atttaccacc atgccaaaac caatgagctt atcatcgaaa atgatcagca
    12301 ttataatcct gactttgcat ggaccatcta ccagctagat accggagagg agagaaccat
    12361 tcgctttgag gagctagccg gtcaggagac aagctctccc tactttatga tgacctcaag
    12421 caactactac ttcctctttc caaaaaggct ttaccgatac gattgtagta accatcagat
    12481 gacctgcatc aacctagatc agtacggagt gacgcacgcc catgccttga tcgctaagcc
    12541 cacaccataa atcacaacag gcctaatcac cactcattca tctacacccc aatgcttaga
    12601 caaagcagtg tactgacccc caaaagttgg acacgacata ttagtgaaag gatttagttc
    12661 tgtattgcac agggctaagt cctttcacta atatgtcgtg tccaactttt gggggtcagt
    12721 acactttggg aaagtatgta tgaatctcca gaaaaaatac cttatcaact acctctatat
    12781 gacaagtatg agggaaataa tagtttattt agagataatg cctcaccaaa ttttagggcg
    12841 gatgtcaaag atattacagc tactttagtg gctgttttaa gtaatggtta tccaaccggg
    12901 aaaagcagtt tttgtaaaga ctactgtccc gatgaaatca gggcaagaca attaacccaa
    12961 ttagctattt ggtattttac agatggtatt tctgaagaaa cgttgaaatc aaattatagt
    13021 ctaaatgatc ttgaatttca aggattaaag tatttaatac aggctggcaa aactgctggg
    13081 actagtaaca atcgaacttt agatatctat atatctaaag atagaaattc aaaatttcaa
    13141 aatcttttag gttctacctt agtagttaaa actccagaaa acaaagagaa ctgtcaatgt
    13201 actaaaattt atatagaaga aaatggaaaa gatggttatt atctttacat ctatgaggat
    13261 acgaataaaa acgataaata tgacaaaaac aaagataaac tactacagaa aaaatacata
    13321 aaaaatggga aagacggcaa gcctggccta aatggtcaac gtgggcctca gggcgaacct
    13381 gggaaacaag gaccacaagg tcctagaggt gataaagggg aaaccggaga aaaaggacaa
    13441 gatggtaaac cgggcaaaca aggtgatcgt ggtccggctg gacctcaggg gcctagaggt
    13501 gacaaagggg aaactggaga aaaaggagac cctggacgta atggtaaaga cggtaaacca
    13561 ggtgaaaaag gggatcctgg gcaacaaggc attcctgggc ctaagggtga tcctggaaaa
    13621 gatggagaaa aaggtgaacg tggggagcaa ggacctcgtg gagaaaatcc cactcctacc
    13681 ccagatccaa tgccacaacc aatgcctgac cctgcaccta aaccagaatc caagccagaa
    13741 cctaagccga tacctcaacc agaggttaag cctcagccag agacaaaacc tcaacaacca
    13801 aacaagccat caaccattac tagccaacct agcggcaaag cactaccaaa aacaaacgac
    13861 acaggcagct tgataacagt attgggaaca ggcttgctct ctcttcttgg actgggcttc
    13921 ttaactagac gcaaaagaaa acaataatta aagcactatc tatagctttt taatcattgg
    13981 ctatcaaaca aatcacaaaa aagcttatcg ttttactcct aacgataagc tttttcgtat
    14041 tctctattac ttggtcccaa tactattttt ccagctttag gctggttttg ttaatccaaa
    14101 ataatatcag acaatttccg ttttaattaa aaaaaaaaac gaaactgcgg aagctaatta
    14161 tcagaaaatg attcacagct tagagtcacc atgttaagct attctacgga gaagaaaggt
    14221 ttgggaatga ctatttctaa actcaaagga gagaaacatg agaaaaacaa tgaagaagat
    14281 gctagcagcc tcgacagtct gcatcatcat gtcgggcagc tttatcggag gcgcggcaag
    14341 agtactggca gagcagtact atggctatga tgatggaaca aaagacggtg gagactggcc
    14401 agtattttta tatgtaacac caacaaatca ccccgaaaga aaaaccgata aagagcactg
    14461 tgtctattgc tttaacaggt taaatagttc acctgagctc tgggaatctc aatttaaaga
    14521 tccaagtaag ctaggtataa aactccctat ctatgaaaag aaagaaggag atgaaagcct
    14581 tttaagagct aaatctcaga agcccagtga taacttaact tcaaaattag ttactgttct
    14641 ttcaaatggc tatcctaata agacattagg taatttaagt gaagatcaaa gtcgccgatt
    14701 aacacagcta gctatttggc actttactga tggatacgct acaaatcatt tcaaagatgg
    14761 ttatcatcta aacaaagatg aagattcaga attaaaaaag ttaattgaaa ctgctgaaaa
    14821 aaacttccaa actacagcac atacctatag cttaaatctt tatgtaactt catcatataa
    14881 ttatagtaca ggtaaatttt atcaacatct tcttggttcc actttaacac caaaacttcc
    14941 gaacccaaat ccaggaccta aaccaccagg tgggaacaat ccacatcatt taccaggtga
    15001 aaatggtcaa actaaatatc cagaaggaga aagcggtgag gcaggagctc ctaaaaagcc
    15061 cgagcctaaa ccagagccta agccggaacc aatgcctaag ccagagccta agccacaacc
    15121 tgagcctatg ccagaaccta agcctaaacc ggaacctcag cctaaaccag cgcctcaacc
    15181 agaggttaag cctcaaaaac caaccaagcc atcaaacact actagccagt ctagcggcaa
    15241 gggactacca agaacaaatg aagcaggcag tctaatgaca ggacttggaa caggcttact
    15301 ctctcttctc ggattaggct tcctaacaag acgcaaaaga aaagactaag acactaaaag
    15361 attatctata gtcgtttagt tgatcagtat ctagtctaat acaacacaaa agccttatcg
    15421 cgccataaat ggaacgataa ggctttttaa gcttggttca aaaagggtaa gacaacttag
    15481 tctagcgatg taaaggcttc atcagcacgc ttgctagtac cattaaggtc atggctgcta
    15541 caaacaaggc caagaaataa ggccaagcct cacctagatt accgccattt tggaaagtgc
    15601 tgatgatggt taacacccaa tgttgtggga gtagctttcc aatcgcctgc atataaggcg
    15661 gcgtaatact aagcggccac aaacaacccg ccagcataga ggttggcatc acaatcagat
    15721 tagccaattg actgctttgt tgcgcatttt tagaaaccgc accaatcatt aagccaaagc
    15781 ctatagctaa caaactataa agaaagaaag tcaacaaaac aatggctgtt ggaatgtaaa
    15841 agctgacatt tgctaccctg agtaatccca gcataatcac tatttgtatc gcaaaggcaa
    15901 caataccaac acagacatag ctcagcatgt attgaaggct tgatagcctt gataagacta
    15961 agcgattgta gatttgactg gacttatcaa gcaagatacc accgtacaag acactggtgc
    16021 tgcctagcat taggatcaat aaaaagccag ttgttgtcga ggaaacagac ttactttggg
    16081 aacgatcagc tagggtgatt tctttgacct tgtaggatag cttcgtgtta tgagctgaaa
    16141 tcttcttgaa aacctcttga ttgcctgctg ccgcatcacc aatgatattg taattctcca
    16201 agagataatt agcctgcgcc ttaaaccatt ctgttatttg actatcagca atcgaacgta
    16261 gagcgatctt ttgagtgtct ccttttagaa ccttctcacc aaagcccggc tcaatggtca
    16321 gcacagcctc cagtgtcttg gcctttaggt attgatcaat agccttttcc tctagcctag
    16381 tatatatctg atatttttta ttgtgcttta attgcgacac aaactgcttg gaaacctgac
    16441 tcttatcctt atctaagatc ccaatcttag cttgacttcc ccctgtaaag ctcaaggaca
    16501 aggccagcat tgttgttagc ataggcaaca ggataaaggt gatatagctt gtttttttac
    16561 gtctaatttt gataaataag gctttaataa aaggaatcat gctgccacct gctttctcat
    16621 tctgaccaaa gcaaagagga taaaggctgt tcctatacca agattaacca ttaaggtaac
    16681 cggtatggga ttggactgcc caccaaaaat aagataaaac aaactatcat tgacccattt
    16741 tatcggggaa atattagaca gctgattaat caaggcgcta tttaaggttg acaaaggaat
    16801 atagcttcct cccaaaaagg caaagacagg aatgactgca ttagacgcta ccgtcaaaaa
    16861 ggattgattt ctaataccag tcgcaagccc gataccgatg gcaacagaca aataaactag
    16921 cgaggccgtc acaccgataa tctgccagtc attagtcccc caattaacac gtaacacaaa
    16981 tcgggtaaag acataaagaa tggttagctg gactgctgtt gctagcatac caccaattaa
    17041 ttttccaagc aaaatagcac tatttgagac ccctgtcaaa taaatgcggc tagccacccc
    17101 ttgctgacga tctgatagca ccagattcat cgctgacata atgctataaa aggtaatcat
    17161 ggtaaacatg gaaatagcat agtaatccgc tgagctcatg cctttactgg tttgcacaga
    17221 gctagaggcg atatagtcta tttttctttt cttgatgttg ctaatggctt ctggataaag
    17281 gttagcaatc gaatcatagg tcttggcatt atccacatag atattgacaa gcatattaat
    17341 caaatcagca ttctgttggt taatgctgtt ggtggtcacc tcaatgtttt ggtcgctctt
    17401 aacctctaga gctgccgtca aggcgccctc gctgaccttt tgcttagcct tagcgatatc
    17461 cttggtttct ttagcttcta aatgaagctc tttatttaac agctttaaaa acgtgataaa
    17521 gttcttttga tactctgttt ccttgccctc aagctgataa cgaaccgtca atttaggaac
    17581 agtagctgct gtattaaagc tggacttaaa agcaaagctt aaaatcagaa tcatcaagat
    17641 aggaaaaacc accatcatca acaaagcagt ccgatcccta aaaatctgta agctttcttt
    17701 tttgattaaa tgaaataaga tcataacaac ccctaatctc ttagcttctt accagtcaaa
    17761 tgcaggaaga tttcttctaa attcaaatgc ttatgcctaa tctcactaaa agcaatatga
    17821 gcatctgtca gctgacgaac aaccgagcca atgtcttcat gttcaatcag gagaactgct
    17881 tcaagctcgt tatccatcag tctccaattg ggcttattag agagatcgat tgcttggtca
    17941 gctgcgactg tcaccatgat ttgctttgtg aaatcagact catagcgtct ttctagctcg
    18001 gcctgactgc cctcttcaat cacctgacca tgatccataa tgtaaatgta atcacataag
    18061 gcctcaacct cttccatgta gtgggtcgtg taaataacag tagctccttg ctcatttaac
    18121 aagcgaatag actctaaaat atgattacga gactgtgggt caatccctac cgtcggctca
    18181 tcaaagatga ttagcttagg agaatgcacc aaagcacagg caatgtttaa ccgtcttttc
    18241 atacctcctg aaaactggct tggaaactgg cttgcctgtg attttaaccc tacgaactcc
    18301 aagcttttta aaacctgctc cttgagctca cttcccttta agccatagag agagccgaaa
    18361 agctcaacat tctcataggc tgttaaatca ggataaacag caatatcctg agggacatag
    18421 ccaatcttgg aactaatttt tcgaatagat ttataagatt gctgtaaaac agtcacttcg
    18481 ccagcattca aagggattaa ccctaaaata gcattgatta aggttgactt accagcgcca
    18541 ttaggcccta aaaggccgta gattctccct tcctcaattg tcagtgagac atgatctatt
    18601 gcctttttgc cgcctcgata gaccttgaca acatctttta actctacaaa actcatatat
    18661 tattccttct ttccaactct aacgctgctc tttaaaacta attaacagat aagttaaggt
    18721 caataaaagc gaaccaatca accaaccata taataaggct gctgtcacac accagacacc
    18781 aatcacacta aagaggcata gggctagtag ctgctgtagc cagcctgagt aacgacaggc
    18841 cttgaccaag gcatagccca aaaccacaag cgtaagacct gccactgaat cttttcctaa
    18901 aaagagacat agacctaagt aacaaaaagc atcaaccagt gtgacaagac ttaacaaaag
    18961 aaagctagct gctgccctat ctggtttaaa ggctagccaa gtcatttttc ctaagagcag
    19021 gcgactgtcc tttttcagca taagatcaaa aagcaagacc aaaaccaaca gggtcagctc
    19081 taccaaggct atgctataca atagcacata acaaatgatt tcccagccaa aggatacgcg
    19141 acccaaaaag gtcagcaaac catcaagagc taaagcatca gaaaataata gacaaacaag
    19201 cactagacca agctggatta gaccaagcaa tagatcaagc cattgctgat aggacattgc
    19261 cctgatgtgc cttaaatgcc atctgactaa gcgccgtctt ttatgacttg ttagaaaaag
    19321 ggtcactagg attaaaaagg atagcaatgc tagtattatg atcatcgtac caccttctta
    19381 tgcattgatt gaagatgact caagccttca acccataaat tgcctccaac atgaacaagc
    19441 aacaccagcc ataagctctg actaacataa taaatacttc cgtaaataag accagtcagt
    19501 attttggcgt aaaaaatgga tctgcccatc aggaaatggt ttagggcata gcacaggctg
    19561 gtgatcaaca agacaagagc aattggcaat cgccattgaa gccacaagat gttaaaccaa
    19621 atcaaacgat aggtgatttc ctcacagcag gccaaaacca agggatagcc tatctgtggc
    19681 catttttgtg tcgttccgac aaatgatagg actaagggaa gccactcttt tttttgccag
    19741 cagcggctaa gatgtaaaaa agcaacctca acaaagagca caacaaagct caagataaaa
    19801 ccaatgatca aaagacgacc atcactatga cctaagggcg ctttaatagg aggtgacagc
    19861 aggtaaatcc ctgttaagac tagggcataa taaaccagta cagctcttaa aaaacctatt
    19921 agattaaagc tatagctatc acgaccctgg ccaaaaatag cctgcattgc gatcgaagga
    19981 caaaaggtag ccattaaaaa gcataggtta aggcattggg tgtacaaagg catttgtcac
    20041 acctccaaac tgtctcatgc gtggatgatt agcaaatgga aaggcaggaa tgcacatctc
    20101 aagaagctca ggagtgagga cacgtgtcac gtaccagcct ttttctgagg cctcaggagg
    20161 agtaatgtct aaaaagacag cattaggact tactttttta gtgtaggcta gtagtgtctt
    20221 taaatcctct tttttatctt tcccagcatg gtttgtcagg tcactaagac gaacctctcc
    20281 tgaaatcaag ggctcaaagg ccttccattt aagctcctga tcctttggat gagcatagta
    20341 aaagacgtta ctatctaggt ctaaaaacaa gggagagtca ctctcagcat tttgtgttga
    20401 cgttggatta taaaacaaat tatagtaata gctatagcta atagctgaag cttccatgat
    20461 tcctcttaac agggtatgct taggatccaa gcccgcctga accccaaata agagataagg
    20521 accttcattg gacttgtttt taaggataat accaaaggta taaagcggat tatcttctcc
    20581 aacagtcatg tcaataggga taatctcata aagactgtcc ttaccaagtc tagcctcttc
    20641 caaaagagct agaatttccg gatcatcaat aatcactctg ggacaaggct ttttagtatg
    20701 ccagctaagc atcatagagt cgatttgaat atactcaatc aagctattac acatggctgc
    20761 ttccagcgtt gtatgagagg ctgtccccgt tgaaaagcct ggaatgatgt gcttttcgcc
    20821 tacagcctga ttggtcttat agccaacgca aagcatttgg gcaggcacat acatctcctt
    20881 atcttcaaaa aacatcggac acttaaccca gcccaagaca tcgtcttgcg tcaccatttt
    20941 atcacacatg atcatgtgca aatcatggca acggtcaatt tgttcctgcg taaaaacctg
    21001 caaatactct aagggcatga caggatccgt ctggctcaat tccttataag aagcataaac
    21061 aatccggtct gataataatt ccccagcaat aacagtggca taacgctcaa tgctttcacc
    21121 taagtatttg atcaaggctt cctcataatg actgccataa ccaatgatat gatagctcac
    21181 ctgactcagc tcaccaataa attgcttgtg gtagtcaggc atctgtcctg tcacactctt
    21241 taagtaaaca tcatgaggat ggttacaaat aggaacctga gattgattta agataccagt
    21301 tcggttacca ctaaggccct ttagcttatc aagaatatgg ttgaacgaag ggtaataatg
    21361 tagcatcctt agacctcctt atgactcttc ttgaaggagt tttttaacaa tctcacgtgt
    21421 tgaaatctgt tgatcctcat accttaattt tgtcagagcc ccttgtgtct gagaattaga
    21481 cattttcaaa atatcctgca cctgaatctc aagcgttggc aaatagacac ttaacaaacg
    21541 cccttcaaat tttgagcttc ctgtttgagc aataataaag gcctcactga caaccagatt
    21601 cattaacaca tttaacaaag gtacataaga ggagctaaca ggctgtgttg gcggcaactg
    21661 ctgacttgca aagcgctgat aaagcgtgtg atcctgtaaa cgtgccagca cccttctctc
    21721 caagctatca aaatcagcac tatgaggagg atttaaggta caagcatgga taaacggccc
    21781 atcaacaaag ccaagcacca attgtttttt caaggccaca ctgatttcat taaggtgacg
    21841 cagcatcata atattcaacc ggccttgaca aataacaata ctctgatagt ctgcgagctt
    21901 ctcagataag cacttcatgt tgcgatggtg ctccagagca tctaagcgag aggtaacatc
    21961 tgtttcttga atgagcattt ttagctcatc gctagccacc tgaaggttta agttcaggtg
    22021 cttggccagc agctcagcag attcattgac atagcttgaa tcactgataa ataagacagg
    22081 tgcagtatcc ttagcctgtc ctgattcagc tatgaaatga taattgcctg ttaagacctt
    22141 catgatattt tcttcaagag cataagcgtc ttcaagcatc aataggtcgt tataatacaa
    22201 ggctgtgatg acctctgaca attttgcaaa taagtcagac tctagtgttt tttcgtaggt
    22261 atcagtatca ataactttcc cgttaaacca atcggagatg atactgtagt aggcttcttt
    22321 taaggcttgt ggctcttgtg caatgtctaa aacagcttca ttaaaatccc ataggccttt
    22381 tctaaagcaa aacgtatcgt caaattgcac aatgcgaaca ttgctattta attgatattt
    22441 cattgagact ccttatttcc aataatcgtc atgtgaatca catgctgggt caagccatcc
    22501 aagcctagct tttcttggag gtattcctta ttgtaccctc caatatcaac acttccatat
    22561 accaaagctg ttgagaccaa ttgaacattt tgagcaatct ctccagcttc aataaaggca
    22621 taagcagtag cttgatttcc atatttacgt gtgtttttga tgtactgata aacatagata
    22681 agaatgacat tgcagttttc ggcagtgatc ggtccgtatt cggcaaaggc tctaatatcc
    22741 tcctgatcac taagatgatg acacctcagc gcgtgctgat aaggaaggta ttcataaaaa
    22801 ccgtccttga gtgtttctac gtttcttgca tagaaaaata aggtgatggg gtacagaccc
    22861 ccaccagaag cacaatttct taaggctact gtcttagtca tgccttcttt gatgattgcc
    22921 tgagagctga caccacaagc ataataaagc aaatcagcca aatcctgcaa aggcatctcc
    22981 tcatctataa actgcctatg acttctccgg ttggtgatac aggttgatag ggctgctgag
    23041 accttcttag ctttaggaag tgctatcgtg tttgccctat cctcaaaata gtcactattt
    23101 gaaaaggtgg tcactgcaga atccgtaaaa aactcagcca cactggtctt aaaccctagg
    23161 taattgttat tagccttgta attcatcaaa aaccgttggc taagattgtc tgtttcatca
    23221 ggcatcaaat gctgtgccac aagctgtttt gatgttttta ataccgtttg atgatgatag
    23281 gttgataacg ataagtgatt ggtattaaat tcaaataact gtcgtgcttc ttctcttgtt
    23341 aggtcacttt ggttatccga acgttgtttt tccttagaaa aaaatggcat aactgtcttc
    23401 ctgtaatata ttaataaata atagtaatta gcaggtaccg actagtacct gctaattact
    23461 acaagacgtt gacatcaagc tgattgtctt cgtctcttgt catgtaacac ccctatccaa
    23521 caccagctaa caccatcaat tacaaactgt aaccttagtc gctagcaaac taatgattgt
    23581 gacctagcta ttaactatta aatagaagta ttaaagttta cgcttttggc tcagctgcac
    23641 cataattgtt gtttatggta gtattgcccc atgaagctga gacgcagcaa caacaagaac
    23701 agcaacagca gcaaccacca ggagcaactt gagttgtttc tgctacacta gtagctaaaa
    23761 tatttgaagc aaattgtaac ataatgctta cctccttata tcgcctgatc ggtaaaacaa
    23821 aacactgata agagttaaat gagaatacct ctcaactgat agcaaaagca atcatgagca
    23881 ggtatccagc aacacaaggc tagctatttt gtatcgccct tgttaaagtg accattcaat
    23941 tcttaccaac tatattatat taaaattcaa gacatatgta aatactttct ttaatatttt
    24001 cttacaaaaa tgtcattatt tttccagaaa ggttagctta ttgagcttga caaagtctta
    24061 agcctatctc tttaatggca tttataaact atcagtcttt ttaatgaaac gcattaaaat
    24121 aggtagagat attattatct ctacctaaac tgtattgatg agacagatgg ctagtacctc
    24181 acaattaacc atttctaaaa ataatgactc ttttgtcgaa agacctaatg attaaagcta
    24241 tttgtctttg tttatctttt tctcattagt aacattaaat catggcaaaa tatttatatt
    24301 catttaataa tcaagattcc ggatcatcaa gtgaccgtcc atgcagacct ttttcgcgct
    24361 gcacctgtct taatttctca ggagtaacat cgtttccgtc ttcatcaaca atcttaatgc
    24421 cttcaatgtg atggcgcact gagcggcgat agccctcaat gtattcctca cgcagcttgg
    24481 cctgctctac cttttcagga ccagtcaagc caactgtttt tttctttttt gcaagctcgt
    24541 taatacgagc gattttttta ggatccataa atcacatata agggctgcac caaaagcagt
    24601 gagcagctga tgaggcttga tgatgggcta gacagcctct ttaggaccgt tactaggacc
    24661 tttcaagtcc tttttcacca gctgtgccag caagggctgc ctgcaaatgg ggctgcctct
    24721 aatcctttct ctttcgtttg tgacatagag tactgcactc tttttgtcta tatctaaggc
    24781 tgtgccagca gctgcttagc cttatgcttc tgccaagaag gctgtagcaa gcttcttgtg
    24841 aaaagctaaa atccatgctc actttactaa cagtgttcct gatgctttta ttgaccactg
    24901 accagcacag ctattgctag caaagctagc ccaagacgat atctcgtagt aagcaagagg
    24961 actgatttga ctaagtatca attgcttgat aagtcttgag tgcttaggga aggacttatc
    25021 ccaaggcagg taatcagtca cctatatcat ctagggaata cgaacagcta acacagggcg
    25081 atgtgcttaa tcttacacag cgaattattt agtatttaat cggtcaaagg ccgcaatggt
    25141 ctctaccttt ttaaccagct ctgctaacag cgctaaacgg ttacgtctaa tagcttcgtc
    25201 ctctgtcatg accatcgtat ggtcaaaaaa gtcatcaata actggactaa gggcaaagac
    25261 ctgagctagc tgttctttgg ctgatccaga tagcactagt gaatcaacag cctgtgccaa
    25321 agccctttcg tagtcatttt caaagaggct agcatcaatc agcacagcgt caactgcctt
    25381 tttcgctaga ttaaagacgc gagacagcga ctcgacagca ggcttgtagg tgtctagctg
    25441 gcttgccgca gccagagcct ccgctcttgc taacagttct ggtacaacaa agcttgagct
    25501 agccagaact gcttcacgta tatcctttgg aatggctgag cccatcattt tatccacacg
    25561 tgcacaaata aagtccagca cctcagcctt atgctgatag gtcaagctat caaatgacag
    25621 ctcatatagg ctatcaatca gcttatccat aggaatgctc cagccgaaat gctcaagaat
    25681 tcggacgatc ccctgagttg cacgacgtag ggcataaggg tcatttgagc ctgacggtat
    25741 caaaccaaca gagaaaaagg acagcagggt gtctagctta tcagcaagag caaggacagc
    25801 accaaccttt gtttcaggca gctctccttc tgccgaattt ggcaaataat gctcacgaat
    25861 tgctgttgcg acagcagcag cttcgccagt taaaagggcg tatttctccc ccataatgcc
    25921 ctgcaactca tcaaattccc caaccatacc agttagaagg tcaaatttat aaatctgggc
    25981 agcacgagcg acagcacttt tttctgcttc tgagagccca gcctggtcag caagaaaggc
    26041 tgcaataacc ttggtccgct ccatatgctc agccacagag cctatctttt catggaaggt
    26101 cacatgagct agcttagcaa ccaaatcttc aatagataac ttttgatcct cacgccagaa
    26161 aaattctcca tcttcaagac gagcaacaag caccttttca ttgcccttaa tcacattttg
    26221 aagatgctta gcattaccgt tacgaacaga aataaaattc ggcattagct tgccagcctg
    26281 atcacgcacg acaaaataac gctgatggtt cttcattgag gttactagaa cctcttctgg
    26341 gatttccagg tacttgggat caaaacttcc catgaaggca gttgggtatt ctactaggtt
    26401 gagcacctca tttaagaggt cctcatcaat atccacctga accttttgct ctgcttcgat
    26461 ggctctgatt tgtgctatga tcatctcttg acgctcctta gcagaggcaa tgacaaattg
    26521 gctgcgcagg tcagcctcat aggaatcagc acttgtaatg ctagtctctt ctccaaggaa
    26581 gcgatgtccg cgactgatac gtcccgaatg aatgtctaaa aagtcaagct ccaaaggctc
    26641 atcatctaac agtacaatca agctatgcac cggacgaata tagtcaaagc tattgttagc
    26701 ccagtgcatg ctgactggga aggtcaagga agcaagaacc tctggcaccg ctgctaagac
    26761 gtccttagcc tgcttgcccg cttcatgctt ggtgacataa acgtattcct cacctttgac
    26821 ctctcggaat tcgatgtcat caacagtcaa gccctttcca cgaacaaagc cctgagcggc
    26881 ttttgaaaat tgaccatctg cgtcaagagc aattttttta gagggtccct taaaatcctc
    26941 tgtcagatca gtctgctgat cagctaagcc cagcacacgc actgctaaac gacggggcgt
    27001 tgaaaagcct tcgattgcgt catagctaag ccgattggcc ttaagaaaat cagccatacg
    27061 ttcaacaagc tgcttttcac taggtgtgac aacgtaggca ggaagctctt caagaccaag
    27121 ttctacaagt aaatcttttg tcatcattaa aatcctatgg gcatcaaatc taaaagagaa
    27181 gaccaaaccg atcctagcat gccttgggca agcttggacg atcctttgtc tacaagattt
    27241 gtcccatctt tctttccttt cttcaagtta tggggtaggt ttaggagacc aaatcactag
    27301 ctcctaatcc tgcaagcctg ctaataagct gcctgttaga caagatcact tagcagaaag
    27361 actgagctta acaggactag tcatcaggcc tttaagtctc atcgctttta aaaagcacct
    27421 accagatagg taagctgcta gcagcaacta gagcttacaa gatcatacaa gctgcattga
    27481 ctacaaggaa ctagtttaga tccagctgct tagtcctctg ccagcaaggc tactcggcta
    27541 gcatcatcca acaatgggaa gccaagcttt ttacgctctg caacaaaggt tttagcaacg
    27601 ctacgagcta aatgacgaat ccgagcaata tagccagcac gctctgtcac agagactgca
    27661 ccacgagcgt caagcaggtt aaaggtatga gagcatttca agacatagtc ataggctggg
    27721 tggacaagcc cttgtgctaa agcacgctct gcttcttttt caaatatctc aaagttttca
    27781 agcagcatgt cctgattgga tacctcaaag gaatacttgg aatgctcata ttctggctga
    27841 agaaaaatct cgccgtactt aacaccaggt gcccattcga tatcatagac cgaatccacc
    27901 tcttgaatgt atgaggccaa gcgctctaag ccataggtga cctctgctgt cactggtgat
    27961 gttgctaggc ctcccacctg ctggaagtag gtaaattgtg taatctccat accatcaagc
    28021 cagacctccc agccaagtcc agctgagccg gttgaaggat tttcccagtt gtcctcaaca
    28081 aatcgaatat catgctccaa tggatcaatg ccaagtcttt caagagattg caggtaaagc
    28141 tcctgaatat tacttggaga aggcttcatc accacttgaa attgatggtg ctgatacaga
    28201 cgattgggat tttcgccgta tcggccgtca gcaggacgac gagatggctc cacataggca
    28261 gcattccaag gctctggacc aatagcgcga aggaaggtat aaggactcat ggttcccgct
    28321 cctttttcat tgtcataggc ttgcattagc atacaacctt gatcattcca atattgctgt
    28381 agcgtcaaaa taatctcttg aaaggtaagt ttgttactca tgatttcctc tttctatttt
    28441 ttatgtcttg tcgcaggcgc taaccaagag ctggctatgg cttgactgct ggttggctct
    28501 taaacagctt ttcaaagaga aaaaccgcgc ctatagccac ctacacctaa aggcataggg
    28561 gcgtcaaaac gcggttccac cctaatttat tacttcattt gatcttgttg ataaacagat
    28621 gtcaagcaag ctacaaacac ctgagcctac tctttagaga aagcgccaac cagcagtacc
    28681 atcactcggc tctcaccagc cccgagctcg ctttagatca gaaacctgct attttctttc
    28741 ctattggtta gtttatcaca aaatcctatg attgtctaat caactattat gattttggac
    28801 gagttccgtt tggaataata acctcagaca agagcctatt ttcttcacga atgcgcagat
    28861 aaatcacaat aatatagcaa gggaaaagca gcattgccgt aatctgagca tggcaaagca
    28921 aagcaatacc aaccagctct ggagcaatgt ttaaaaagta attggggtgc ttaacagtct
    28981 taaagagcca atgatcgaca tatttatggt cctttgccag catcagcttc actgtccaaa
    29041 tatctcccaa gatccgagtt acctcatata gcacagctat cgaaaaaatc atcagcagca
    29101 agccaagaaa gctaatgcca tcaaacttaa tctgcttgag caatgcctct gtcacagcaa
    29161 agacataaat catgatatgc agcagggtca aaaacttagt gttttgcgca ccaaattcct
    29221 tgcccccatt agccaggata gccttctcgt ttttgatcga tttttttaag aatactaaac
    29281 gaatagcaaa catcaagagc atcaataaca ggataatcaa agtaagactc ctttattcta
    29341 gtttaatctg tttctttcac gaaacactaa ttaagattat agctaagtta cacagccttg
    29401 tcaaaccgtt ttcaaaaaaa agatgtcttt ctttgatctc taaaaacaag aggtcgtcac
    29461 acagcaccat caagagacct catcaaagct ttaaggtcgt accaaatcac catcaaaaga
    29521 cagctcctag actcagtcaa ttcacgagca gcaagcagca cccaagaggc attttgcagg
    29581 cctgacctac ttcgcctgtc gtaaacacaa atcctcaata tggtaaatag cgtcacattg
    29641 cgctgcaacc tcatcgctgt gtgttgccat taagacaatc atatcctcag tctgacaagc
    29701 tctgatggct tgtaagacct cctgctcagc ctcaatatcc agggcgcctg ttggctcatc
    29761 tgccaataac agctgcggtg ttttgaccaa agcacgagca aggaccacta atgtagctca
    29821 cttaatccct gcagctcttg ctaaaagtcc ttggtatcag gatctgggat agctgacata
    29881 cccggcaggc aacgaatgcg ctctgaatcc tctggactaa tctcacaatc aaaaatagcc
    29941 atattttcta ctatgcgttc cttgtgcacc gacttaggta gaggaataaa gccctcagca
    30001 atagaccaag caagggctag ctgagccact gtcttgttgt actttttagc caatgcctgc
    30061 atggtatcat cggcaaatat ctctccttgt cctaatggac cccaggcctc tagcaaaatg
    30121 tgatgcctgc ggcaataatc aaccgtctct ttttgatagc agccaggcgc caagcgaatc
    30181 tgattgactg ctggtgtaat ggttgctgtc tgtttaagag cctccagatg gtgaaccata
    30241 aagttgctga caccaatcga gcgaaccaag cctgcttcaa cagcctcctc catataagac
    30301 caagctgctg cattggctgc ttgccagcaa tccctaagag ccttaggatt tggccaatga
    30361 atcagataaa ggtctacata ctctagtcca aggcgctcaa gagaggctgc taaggctgcc
    30421 ttagcgccat catagctatg agcatcattc cagagcttag tggtaataaa gagttcttca
    30481 cgaggaacgc ccgaatcccg aatggcctgt ccaacacttt tttcattgtg ataaatggca
    30541 gctgtgtcaa tatgacgata gcctgcctta atcgctgcta gggtggattg gtaggcctcc
    30601 tcaccatcag cagccttaaa ggtcccaaag ccaagcactg gaatagcaag accattagcc
    30661 attgttactg ttttaatcat atctaaaacc tcctttttca ttgtagcaca atgataagca
    30721 aagcaaaaag aattgagctg atcaccagcc caattccttt gctgtattaa gcctcaaagg
    30781 ccttttgacc atttaggtag gttgctacta attctaagtc cttatcaaga acaataaagt
    30841 cagcagcatg acctgccttg atttggccac agacatcttc aataccaacc gaagcagctg
    30901 ggacgtaaga ggacatgtga attgcttctg ctggacttgc aattccccag gcaacaacat
    30961 ttttaatgcc gtcctttaat tttaagatag agcctgctag attaccacta tccttcaagc
    31021 gagctgtgcc attttccaca ataaccggaa actctccaag catgtaatca ccatctggtg
    31081 aaccgcctgc acgcatacag tccgtaatca aagccacatg ctcatgaccc ttttgctgca
    31141 tcaaaatatc gcaagcaaca ggtgagacat gatgaccatc gcagatcagc tctgcaaccg
    31201 ttccaggaat attataaaca gccccaacca taccaggctc acgatgagtc aagccacgca
    31261 tcccattgta ggcatgaacc caaacactag ctcctgctgc tactgccttt ttagcctcag
    31321 tataggtacc atttgagtga cctaaagcta ctgtgacacc ctgcttggtc acctcagaga
    31381 caaatgcttc tacgccatca cgctcaggag ccaaagctat ttttttgatc aagcccttag
    31441 ctgctttttg ccaagctgca aattcgtcta agcgaggatt tttcatatat atcgggtttt
    31501 gggctccctt gtattcctca gtgaagtaag gcccttcaaa ataaatcccc tgaatctttg
    31561 ctcctttgac ctgatcggca acagaagcaa cggttgcaga cacctgctct agatgctcaa
    31621 aggttgacgt tagggtagtc ggtaagaagg aggtcactcc tgttgataag agaccctcac
    31681 tgatggcatg gagaccttct gctgaattat ccatcacatc agcaccagca tagccatgaa
    31741 tatgagtatc tacaagtcct ggtgctattt gatagcctgt ataatcaata acctctgcct
    31801 gatcatcaac agtagccgtc caataaccaa atgtgccatt atttagctcc aaatagcctg
    31861 ctggctttac ctcgttgggg taataaaagc aatctgcttt aatatagctt gtcatctttt
    31921 ttcctccctt tttcgtttat tatacgcctt aattcttatt ttgtaaatgg tatataccag
    31981 tccttctgtt aaaaagaaaa acctgaatac tatttcaagt tttccctttt attagagctg
    32041 tcctgaaagt actttctcag ctagatttag ggcgtggtca gtgatacgtg tgtaatgaga
    32101 tataatgtca ataaaattaa tccctgcctg tgctgtgcat tcgccacgat tgaggcgttc
    32161 gatgtgtgtt ttacgcaatt gacgctcttt ttgctcaatc gtcctatgac gctcaacaat
    32221 agactgggct agagccttgt cactatccac aatcgcccta atcgcatcta aagttaaaca
    32281 gtgggtcagg tgatacattt ctgttaattc accacgtgca gctgctgaaa agccaatctg
    32341 ctttgctgta atcccctcaa tgagagtcgc taacgactca gagtggtcac caattcgctc
    32401 caaatcacga gacgaatcca acagacctgc taaaacctca ttttcactag gactaagggc
    32461 ttcattggaa atatcaacga ggtaagtggt gagctcctca tcaatcgtat tgaccgcctt
    32521 ctcatatcgc ctcacctttt cgccaaactt gtcttctgct gtcataatgt agctataaga
    32581 cgcctcaaaa gcctgaatag cataggaagc cagatgtacc aattccttgt gggcatttcc
    32641 caaggcaata gaaggagcct gagtgattag taaacggtcc aaatacaagg cttcatattt
    32701 gacgatttcg tcttcacctg gaattaaggt ggtcacaagc tttgccagag tgttgataaa
    32761 aggaagcagc aacagggtat ttgtgatgtt aaaggtccca tgtgaaaagg caatggtcat
    32821 ctcaggtgac agggccaaaa cagactgaag ccatagcata aaggaggtaa atggcatcag
    32881 taaaatcata aagatgaccg tcccaataac attaaaaaga atatgagcag cagcaacacg
    32941 cttagctgca atattagagc caatagctgc caaaaccgct gtgatacagg taccaatgtt
    33001 agagccaagc aaaataggaa tcgcaccctg cagggtcaat aggccacccg aaaaaagccc
    33061 ctgtaaaata ccaataatgg ccgccgagga ttgaatcagc atggtcaatg ctgtcccgat
    33121 aaaaacaccc tgaaagggct tgtctccaag cgtcgctagg taatgctgaa aggctgagac
    33181 tgattttaaa ggatccatcg catcacccat gaggttgaga gaaaagaaaa ttcctcctac
    33241 accaaaaatg atacgaccta ggttattgag ttttttattt gacgtgaaaa agagacaggc
    33301 tgctccaata aaaatcatgg gcagggcgta atctcccagc ttaaaaccaa tcaaaaagga
    33361 ggtcactgtt gttccaatgt tggcccccat gacaatacca atcgcctgct gtagggttaa
    33421 aaggcctgca gatactaggc caactgtaat caccgtcaca cccgagctag actgaatcaa
    33481 agcagacata gctattccaa ccaagatacc aaagaagggg ttgcttgtgt acttgtcaat
    33541 gtaataccta agcttatcac ctgcggcctg ctgcaagtcg tctcccatgt atttgatact
    33601 gaaaagaaaa agacctaagc cctgtactgc cccccaaaaa atgaaacgca atgtcttgcc
    33661 aatttaccga cacaatattg tcctcactcg cttatttatt ctcttctatt ttaatgtatt
    33721 tattcagtta tcacaagggt tttttaatcc ttttaaatag tgctcattta gaacctattt
    33781 tagagcccta gtcctctttt cattttccta tattcagggt ataatagtgc tactcaagcg
    33841 acaatgattt caaaggagat accatgagaa aaccgacaaa agagacccac tacctcatca
    33901 ttagcttgct tactattgcc attgcaggag gggcctacct tatttttagt agcctctctc
    33961 caaagccagc taccattacc acccaatcta agggctatga gctgttaact aaggctcaag
    34021 cattagtcaa ggaggccgaa gacaacccaa ctaaagaagc tatcgcaaag gctcaaaaag
    34081 caattaatca gctaaaaaag acccagtcta aggaggaatt acaggctcga ctaacagcta
    34141 tcagcttaaa gcacaatcaa gaagacgttg ctatcaaggt cctaaaggca gccgaggaca
    34201 atccaagccc tgaacttaag gaggctgcac aaaaagccat tagtaagctc tctgatgagg
    34261 ctaaaaaagc tgccttacag gctagacttg acgctattgg actttcaaag cctagcactg
    34321 cacagcctga gactgcaaca ccagcagcag aaaaaaatat agcaccagct cctgcggctc
    34381 cacaaataaa gcataccaca ccgtcttctg ggggaacgac gccagcaccg aaccctaaac
    34441 ctagtcctaa gccgaatcct cagcctagtc ctagtccagc tccagagaac ccagagccaa
    34501 cgcctagtcc taaccctcag ccaaatcctc aaccagaaac caacacacct agccctcagc
    34561 cacctgcaac agagcaaagt gaaaacactg ctccagcagg acaaaactaa gaaagggcag
    34621 ccagagctgc tgtagcttag ttacacttct tagtacaggc aataagggct tagctactga
    34681 aataatgcta aacttacgac taataagctc tctgataaaa agaggcttta ggtgattaaa
    34741 aacagctggt tctaaaagga ttccagctgt ttttgtgctt cttaattgat tttgaggtag
    34801 gaagagaagg gaggcttaat caagtcgata agtaatccca tatcctctcc taactctcta
    34861 tcagcttggc tatgattata gagcggctca cccttacgcg ctttggtgat tcgtcatgga
    34921 tattctgact ggcttgacca tttgagtttt ttcctcagtg tcactcccta agacttttaa
    34981 gggactgacg aggtgattag catgcacaac aaaaagccct taaacacacc tttaaggacc
    35041 ttgtattcag cttaatgcct ctatagtatc agggatattt gttaaggcag ctctcagcta
    35101 aagacttgtg ataaagacct atgcctatcc gaccactagc tagagtcaag ctgtgcatag
    35161 ctcagcctct atgactaaca gaaaccagag gcagcgttag atcactttgc ttagcttaaa
    35221 cctcatagcc catgagaagc ccttcagctt ctgcatagaa gctgcatagg cctgaggctg
    35281 ggctggtttg aatctctgct tctgggtaaa tcgctctaat tttttccgca atttgctcac
    35341 agatcttagg gtttttggcg tgggagataa agactcggcc tcctttatag cctgcctttt
    35401 gaatctcttc taaaacagct gacactgcct ttttttgacc tctggccttt tgaagcagct
    35461 caagcgtgcc ttccttactt gcctgtccta ccattctgat gtttaataag ccaatcacct
    35521 taccaatgag cttattcaga cggccatttt taaccagatt atcaaccttg gccaacacaa
    35581 aaacaagcct ggttttttcc tgataagctg taattttctc aacaacctca tcaaaagaaa
    35641 gcccctgatt gatcaaccgc tctagctcta acacaatcaa atccatctca ccacctgctg
    35701 acaaagagtc aatcacatgg atattggcat tcggattttc ctcaagcaag tcattttgag
    35761 ccaatctagc actattgtga ctgcctgaga gcgtaccggt aatggtaatg gcaatgacgt
    35821 tatctgctcc cctgtaggct tgtaaaaaag catcaggact tgggcagctt gaggttgctg
    35881 gcttagagga ctgatacata gtctccatca tttgatcaat atctagacca tcatcatctc
    35941 taaaaatatc tgaaccaatc tgtagggtta gcggcacacg ctcaaagcgc aggtgattgg
    36001 attggctttt tagggctcta atatcgcagc ctgaatccga tacaattttc caggtcattc
    36061 gttttcctct tttccttcat agtctgtttt ggttgacaaa gtaagcattt tcccataaaa
    36121 ttatatcatc actagctaga cttttgctag ctaaacgaca tcagatgtaa cacttgaaag
    36181 gtatttgtaa tggctggtaa accaatttct aaacagtccc ttcaaaattt agcccactgc
    36241 aatcaggaat ccagacggtt aacacgagaa gctattgaaa ttgctctgct tagcttacta
    36301 gaaaagaagc ccttaggaca cattaccatt tcagaattgg tagctagagc tggggtttca
    36361 agaaatgctt tttaccgcaa ttacagctca aaggaggata ttcttgagtg tctgttgact
    36421 tctgttatca gacgtatctt tcgtggactg aaggcctttg atctaaagac acaggcctat
    36481 caggcatggc tttatctgtt tacagaggcc aaaaaagaag cgacgctact tagtattatc
    36541 tttaaccatc acctgcagca gctcttgacg cagatggtta ccaagcgttt gagagcctac
    36601 caaaagtggc aggaaaaaaa gctgtctcac tacgcactgc tcttttggag caacgctatt
    36661 gtctcagtcc tttccaattg gatttctgat gatatggttg ttcctgctga ggagatggct
    36721 gctatggggc tgcccttatt agcctagttg tctctagatc acctatagct cctagacaac
    36781 ttcccaagaa accaagcttg cagcatcaga caggacgctt ggctggcttg acttaagcac
    36841 tggcactgcc taccaagata tgtactagcc ctactacagg caaggtgtga cttgtcgctc
    36901 gctgttgtgc agaggcttaa aggctcttac atttagctgg acaataaaaa aagactgaag
    36961 aggctggctg gattagcctg ctcttcaatc cagaacctcc tttgttggag gttttttcgt
    37021 gttttatttt tcagtcgatc tcacacacct aggcttgtgg tgttccaaga cagctcagct
    37081 ctagtcaaca cctctaaaac tgagcttatc atctctagct tttggaggcc ttttctgacg
    37141 ggctggtttg actgtgctta agagcccttt gtcaatgcaa attgattaat ggcatgggcc
    37201 acgcctgctt gatcattgga gaggcttacc ttgtcagcga cctttttaat tgcctcatca
    37261 gcgtttccca tagcgacacc taagccagca taggctaaca tttcaagatc atttgctgca
    37321 tctccaattg ccatcacttg gtctgggcgc agcttcagat cagcggttaa ttccttcagg
    37381 gcagaggcct tggtcacaca ctccggcatt acctctagga ttgtttcttg actgcgaacc
    37441 acactaaagc ttgcgctgag tttttctcta acaagagcct caaaagtatc tagggcagcc
    37501 ttttctccca tgtacatggc ctgaaatatg atttgactgc tgttggataa ctgagatagg
    37561 ttagtagcct ttacctttgt aaaaaccaaa tcaccatcag cctgaaccat atctggaacc
    37621 ttgctatcta tcacaagata atcacgctct ccagtcaggg tgaggtaaat atctgaaaag
    37681 ggctgagaca gctgataaag gtgctcaata gctgaaaagg tcaggctttg ataatgtagc
    37741 agctcccagc ttgggctcct ataggtgcta cagccattgt ttaaaataag gtactcctcc
    37801 ttatcactca agcctaattg ctcaaaatac ggccttgtcc cagactgggg gcggcctgtg
    37861 cagagaacaa cttttatccc ctcttgtgca gctgcttgga tagccttaat attctctttt
    37921 ggaatgtgct ttttgctatc aagcagagta ccgtctaaat caattgctat aagctgaatc
    37981 atcgtctcag tcctctttcc attttatctt aggtaggtgc cattgtcttt tgttgccaat
    38041 catacgcatg actgtcaata aaacaaccag caagtagcat tcaacatttg aagtggccag
    38101 cttaaaataa agcacaagtg ctgctataat agaccagcca gcataaatct cacttctaag
    38161 aacagttggc ttacggcctg ccaggacatc tctgaccaca cctccgcctg cccctgtaag
    38221 aaccgctgct acaataacag cgcttaaggg ctgggctagt cgaacagcat gtagagcccc
    38281 ctgaacacta aaggctgcaa gtccgatagc atcagtcagc accgctgctc tcacccagcc
    38341 cttagccaca agcttaggaa atagcatgat cagaataata gctataaaag cgcaggcaaa
    38401 ttctggtctt tgtccccaca aggcttcaat aggcagcccg atcagggtat ttctaatagc
    38461 cccaccacca aaggctgtga caaagcctag aataaaaatc cccagaacat caaactcctc
    38521 ctccatagcg acaatagcgc cggacaaggc aaaggctatc gttccaataa tgcttaaaag
    38581 ctcccacata tcaattgtca taactcacct aatgcttcct aatcccctat tagtctacca
    38641 tctttttaat caaaatataa gtcaaaataa gagcaaggtc ctcaaaaatc ctactgatga
    38701 cctgtttttg tttgcaccaa agatttagcc cctatatagg ctaggctcct agtagcagga
    38761 gttaggagcg atagcttgcc aaattcacag ccttgttatt ttccatgaga aagggctctg
    38821 ctgatgtctt ggtttgatag gtcttgtatt tatggtagag gtattggtag caatcctgtt
    38881 tttgatcaaa gaggatggct tggtagggct cttggaagga caatttctca acaaacagat
    38941 acttgctctt atactccact agcactccca catgaccaat aaaaaggtaa tcaccatcta
    39001 gctgatcgtg aatcacaaca gcaagcattt tggctgggcc attaaagcta acagctgaga
    39061 aatgctcttg catatgcttg gcatgcacct gaatatcctt ggtggcttcc gttttcactc
    39121 ttgaaaacag ctgcttaaag cgctctgtct ctgcctgtgt aaagagctgg cttgtggtaa
    39181 tggcgtcctc gtccataaat aaaagcgtat catcactgct ggtaggcgca atcgtcatgc
    39241 tatcctttag aagcataaag gtgttgatcc ggcaattagt tccaatgaaa ttgccttgct
    39301 tttgcgacca caactcatcg attgctacca catcatagtc aggctgcttc tgataggtaa
    39361 aggcccctgt caagcctgtt ttgccaacta ggctattata ttcttgtaca ccagccataa
    39421 aggcattgac attagcttcc ttcagctgat gtgatagggc agccctgacc tcctgctggc
    39481 tctttgcact gttcatgttg gataggaaaa gacgtccctt cttagcctgt ggctcttttt
    39541 gctcctgctt gggctgatca gactggtgag aagcctggca agccccaaga gttgccgtag
    39601 caaggattag caaagacatc attacttttt tcatcataac ctccttttta atgagtcatt
    39661 caagctggta ctctccatca tcaccaaatg agattatcag cagctggcag ctaatacgag
    39721 gttgctacaa cccacttgtt atctctttat gtcatgacct catcgttacc agtatagcat
    39781 aaaaaagaaa agcaccagct cttgaagcct tgcagccctt gtgccggtgc ttttcgttag
    39841 gagattacac tgaaatagtt tttgtggtag ctagctgctg ataccaataa gcgctttttt
    39901 tagggtaacg cttttgggtt tcaaaatcaa catagaagag gccataacgc ttatcatagc
    39961 catttgacca agaaaagacg tccatcaagg accagataaa atagccctta acattagccc
    40021 cagcaccgat agcgtctgca atcacagcca aatgctgctt gatgtaatca attctagcgt
    40081 catcatcaat cctgccatca atacaggtat ccttgtagcc aaggtcattt tcagtgatat
    40141 aaatcttttt atagcctgga tagtctgcct tgatccgcat gatttgatcg taaagcccct
    40201 gtggatagat catccaatcc cagtctgtac gcggcacatc aacatcaaac acgcgttgac
    40261 caaccccctt tatctgatat ttggagccgc ctttttctcc cttgccatta tgaatgattt
    40321 cggtctcacc atggctaata ataagccaga cttctcatca cgtaccttag tggctggcag
    40381 gccatattca gggtctagca ggatagagga ggcatagggg gttagctcct ctgataccag
    40441 agcctttagg gcttcgattt gccaaggagc tggctctgtg tcttggtggg ctgccatcat
    40501 gcgctttaaa gccccgcgtt gatcaaaggc caaggccgaa atgattccct tacgactgac
    40561 cttttctaaa taagcttttt tgtttcttgt taatgtcatc ttatacctcc tctacttgaa
    40621 tacggtcaaa tagctcatca aaatgtgcca tgttaacatg acctgttctt gtttcttgcg
    40681 catttaacat gcctaaaaca ttggcttttt tcagaagcgt ctcatcgtca tctccttctg
    40741 ccaaagccca agcaatccct gccacagtag cgtcaccaga tccaacagga ttgactacct
    40801 caattttagg aatggtaaca cggtaaaacc tgttatgatg tttggcaaag gccccttggg
    40861 caccaagaga aacaataatc cattctatcc cttcaaataa aggttgactc aacagagaga
    40921 ttaaacgttc ctcatctaat gtgacaggtt ggcctatcaa atcctccaat tcttccaaat
    40981 tgggtttgat aacagttggt ttatctttgc cagccagtac cgcttttaaa ggagcaccag
    41041 agcaatctaa aaccactttg ctgccataga ctctcgccat agtaatcaag tcttgataat
    41101 agtgagcggc cagaccctta ggcagactgc ctgaaaaggt taagacatca aactgcttag
    41161 caataatact catgtggttc aaaaagcctt cggcctcgtc catatcaatg tagggaccag
    41221 cttccagaat ttccgtctgc atgccttcat gtaaaacagc aatacaattt ctcgtttccc
    41281 ctttgatttt gaagaattgg ttagaaatgc cctgttcttg taactgatga atgacaaagt
    41341 cacccagttt cccaccaata aatcctgttg ccacaactga ctgaccagct tctgctaaca
    41401 ctctggtcac attcagcccc ttaccaccgg ctgtttttgt cgttctgtca acacgattaa
    41461 ccgtgtccaa agtcagacga tttagaggat aggaaatatc aatggatggg tttaaggtta
    41521 ccgttaaaat catcgcttct ccctaatcgt ggtagtcacc gcgatcccat ttgtccaaaa
    41581 actctgtaaa gaagtcagga tcttcttggt tagcattatg actttccaaa tgggctatct
    41641 tagcaattaa cttcttattc tcttcggttt ccttatagtc tgcctttata aaggcctcaa
    41701 taatatcaca catcaaaagc tcacctgtga ttttaccacc aaagccaatc acattggcat
    41761 tcaattcttc tttggcataa agcgctgttg tcatatccct aacaagcgct gagcgaatgc
    41821 caggaacctt gttgacagca ttagtgatcc caacaccagt gccacagata cagacaccaa
    41881 gatcagctag gccattggcg acagcctcac caaccctttt cccaaaaatc gggtaatggg
    41941 tgcgggtatg gtcataggtc ccacagtcaa tcacttcata gccctttgat ttcaaaaaat
    42001 ctgaaacagc cattttttca tcagtcacaa tatgatcaca gccaatagca attttcatga
    42061 tatcctccct tcgttaagcc attttattga gcatgtcaac acgaatttga tgacggccac
    42121 catcatagtg accagtcaca aaacctttag caatattctt agccaattct tgacccacaa
    42181 tttctgctcc catggtaatc atgcgggcat tgttatgacc gcgagtcatg taggcagagc
    42241 gttcatctga cacttccgca gcgaccatac ctttgatttt ggtagcgacc ataaatggcc
    42301 ctgctccata agcatcaatc ataatgccta gactttcctc atcagccttg agcgccctag
    42361 caactgctag agtattgtca acaaagtcat cagcaatcgc cgtcacatct gtcacatcaa
    42421 agccttcctg ctgcaaaaag cctttaatag cctcttttag atcatttcca tgtgcatctg
    42481 cacctaagat aatagtcata ggatctcctt ttattgtcat taccgttcaa aattgtttat
    42541 ttttgttttg ttttttatta ttttgttgtt tattgaaaaa agagactgtt tatgctatta
    42601 tgagttaaca atacaccaga gaaagtagcg gcctatgctt aagcgtgaaa gattgttaac
    42661 aattatggaa aaggtaaacg ccaacggctt tatcactgtc actgatatta tggaaagcct
    42721 aagggtttca gatatgacag ccaggcgaaa tttagatgag ctagcaaggg ctggaaaatt
    42781 agtacgtatt cgtggcggtg cccagagcat ttctatgcct caaaagctgg agcgttcaaa
    42841 cactgaaaag ctaaccgtac aaattgaagc taaaaaagag attgccagat acgctagtca
    42901 gctcattaat gatggtgaga ccatttttat aggccctggg acaacactag aatgcttggc
    42961 tgaggctcta atcaaccgtc acatccgtat tattaccaac agtctgcctg tttttacgat
    43021 tcttaataaa agtaaaactg ttgatctcat tcttatcggt ggtgagtacc gagccatcac
    43081 aggagccttt gttggcagcc ttgcaagcca gaccatctta tccttgaagt ttgccaaggc
    43141 cttcatcagc tgcaacggta tttataaaaa tgacattgcc acctacagtg aaaacgaagg
    43201 ggttattcag cgcctagcct gtgacaatgc catcgaaaaa tacctgctcg ctgacaacca
    43261 aaagtttaac gcctatgact tttacagctt ttatcacctt gacaatatcg acgccattat
    43321 cactgactcc aagattagtg acagcgttaa ggagcgttac cgccaatttg ccaagctctt
    43381 aatcgcaagg ccagctgaca atcaggtcag cagctagaca gcctgcctct ctatctgttt
    43441 ccaccctgag tccagcaggt aaacaaagct atcaaacgaa atagcatcat aaaagcgcat
    43501 gaagccacta atattgcaat ggggcttcat gcctttttta acctatcaca cgttaagcaa
    43561 agcaaaaaga ggctaggaca aaaatccttc ctcttttaaa atcgtcaaac tatagagttg
    43621 attggagggc tcttagccct catttttcaa gcgatgtggc ctttttaatc agctgctcga
    43681 gggtggataa cctaatcaac atcgccaggt catgacgatt gaatggttat tccactcttt
    43741 ttctacgctg agggctgtga aagggctcat acgacagctt agccgctttc taacagctat
    43801 ttacctacct cacctcttaa cgagcagaca gcctaaatgg tatagtccag ctgatcaaga
    43861 ctctttttat ggtcaaggtc aatatcaaga aaggtcatct gcttgatatt gataaggctg
    43921 gctacaattg ataccggaaa agcaaccacc gcttgattga agagactaat attactattg
    43981 acaatgcgtt ttgctgctgc caaggctgca ttttccttag caatctcatt ttgcaggctc
    44041 aaaaactgct cagaggagcg catttccgga taagcctctc ctacagcaaa aacctcattc
    44101 aaggcctgct cctgtgtcct catcacatca tttgtttcct ccaaggaaag cccctgacgc
    44161 agcttcacga gttcagtaaa gaccttttcc tcatgcttgg cataggactt agcgattttt
    44221 agcatttccg aaatggtatc atatctcttc tcaagagcaa tatcgacatt tcgtttagac
    44281 tcctctataa cgattcgata cctttctaat ttgtttctca ctccaataag ccatagtata
    44341 gtcatgcaaa gaataagtgt taacatagat gacgtcactg acataaaaaa gcctccttaa
    44401 agctgatgat ttagtgtatc caacaagcgg tacatcttaa caagcttgtc ttgaatgttt
    44461 tcatattcgc tacttaacga tagcttttca atagcccctc tagagctagg ggttttcaag
    44521 agctgttgac cggaatagaa ggacacaaca acagtatcac cattcatata aactgctaca
    44581 ggcatctcct ctctccattc atcaagcact gccagcatat aaggatttaa gagcattcta
    44641 gcgcttaatt catctgtgca gtacacattg tacgtttcat taaagcgaat gtcctccatt
    44701 tccagctgca cctcaccctt tagcttagcc ttgtagccac tatggacctt ttctctgccc
    44761 aaaaagccct tttgagtcgg cacaattcta atataaccct tgatagctgt atgatattta
    44821 gccagcagca cctgtccgtt aaaatcagtg acccgatgcc agttatcatc ctcattttcc
    44881 tcatggtagg cataaagatt gcaaaattct gtctgcatgt catctccaaa aataatatgg
    44941 caattactgt cataccatct ggaggacggt gttgcaagct ttagtaagga gagctcaatc
    45001 cctgaatagt aatctatctt gacatctggc agggcctctt gtaaaacagg cagcaaaaag
    45061 tgatccacat aggagagctc atttgctgtt ttgaatgttt tcagccgcgg ccaaaccaag
    45121 ccccccacaa agataatgag aaataaggca agagatcggt caaccatgcc atacaagatg
    45181 attgcgccta tcaccattgc cagccagccc agattattct ttctagcatt tccactcatc
    45241 tcgcttttaa tttgctccag cttttggtga tgctcaggcg aagcttctat agctctactc
    45301 ttctccaaaa caataggatc tgtcaatcgc ttagtatttt cgttcatctc acttactcca
    45361 gatacttctc catcagcagc gctcagctgc tcttgataac accagtcact ttatgctttt
    45421 gcttaaccta taaatgacaa ttgcgttaca gctaatttat aatattatac catttttaaa
    45481 ctattttttc tattattata tttaaatgac gctcaataat aaccacataa tgttaatata
    45541 gacatcattg tgctcttttt tacctaatca tgttgtgagc aatacccccg tttatcagcg
    45601 gaaaccataa aggcctctat gagatcaaga ctatcagcgc cagcccttct tttggagtca
    45661 ctattcagct tgttcttcgc atgctgtctt tgcctgacca tgattcagct gctctttttg
    45721 attgcttgtt atgctcactt tttccgtctc atgctgagca agaaaaaaca gcaaaccctt
    45781 gcttggttta ctgctcttct gttgatgtta gtcaaaaaat aagccgggag ctaatgacac
    45841 cctattaact cataaagcct gttatccttt ctttgtcata gaacaattca cttagtctat
    45901 tctcaaccaa aatacgaagc ctgcttaaac cgtcttctca tattaacagc taaaaagtgg
    45961 tgtcaatatg aagaaaccta tgatcggtaa caataatagc acctttaaat ctctcagcga
    46021 taatgtaagg ttatcctata cctgtcatat ttttcggtgc tatttgccat atcaggttgc
    46081 tatagcactt ggtggcttct ggtagcctta accaataaat gatctgcttt tttattcctg
    46141 ctctttgttt tgtttatgcc ttttgtcggc gcaggccttt agctttacta tactgacggt
    46201 aaggtcggtg agagccttta ccatttttta tgccttaatc gcaaagcatt taacaccact
    46261 gatattgagc taaggctcat cgcaaagcca gccagcattg ggcttaatag agggccgcca
    46321 aagacatgaa ggatacccat agcaacgggg atcattaggc tattatagct aaacgcccaa
    46381 aataaatttt gcttaaccac tctgatggtt tgacgactga gctctaggca ttccaccaca
    46441 tcacgcactg ctgaggtcat caggataaca tctgccgcct caatcgcaat atccgtacct
    46501 gagcctattg agattccaat atccgctagg gtcaaggccg gtgcgtcgtt gattccatca
    46561 ccaaccatag caaccagctg tccgctagcc ttcaaatccg cgataatctg ggccttttga
    46621 gcaggcagca cctgactaaa gacctgatca attcccacct cattagcaat cgcttgagct
    46681 gtgagggcat tatctcctgt tagcataacc gtttgaagac ctaaatcctg caaggccctt
    46741 atagctgcct tactgtcagc ctttagccta tcagcaatca gcaataaagc acatagctga
    46801 ttatccttgg cataatacac tacggtttgc ccctttaagg cagcttgctc ggcataggtc
    46861 tgagcagcgc ttatcgcaat cccctgctgt gacatcagct cactattgcc aacagctaag
    46921 cgatgctggt caatcacacc agtgacaccc aagcccacaa gcgattgaaa atcagtcaca
    46981 gccagcaagt catagccctt ttcctgtgct actctaacaa gcgcttctcc aagagggtgc
    47041 tgcgaatact gctctaagga agccacctcc tgaagtccct gcttctcact agcagcaagg
    47101 gggatgatcc gctgtagctg agcctgaccc tctgtcagcg ttcctgtttt atcaaaaaca
    47161 attgtccgca cctgataagc cttctctaaa atatctcctc ccttaaaaag gatcccctgc
    47221 tcagctgcac gacctgagcc aaccataatc gcggtgggag ttgctagacc cagagcacag
    47281 ggacaagcaa taatcaaaac agctatagct attgtcaggg caaaatcaaa gctctctctc
    47341 ataacaaaga gccaaaaaag aaagctcagc agggataaac ttaatacgat agggacaaag
    47401 actcctgata ccctatcagc aagtgcagca atcggagcct tggcttgctg tgcttgctcc
    47461 accagctcaa taatctgtga aagcaaggtg tcattgccaa gcctagaggg ctttaccctt
    47521 agcgctcctt ggccattgat tgtgccagca aacacactat cacctgtcac cttatcaact
    47581 ggtaggcttt ctcctgttag catggactca tcaaccgtag actgcccctc tactatcagc
    47641 ccatcaacag ccacccgttc acccggttga ataaagcaaa tatcctcatt agtcacctgc
    47701 tctaagggaa taagctgaag tgctccctca cgaataaccc tgacatcagt tacccttaag
    47761 gacattagct tctgaatagc ctgcgaggcc cgtcccttgg tacgcccctc caaatagctg
    47821 ccaagggtaa tcaaggtcag aataaccaca acagattcaa aataaagctg gtgagcaaat
    47881 tgagcagctc cagctacaat cttaaaacag ctatatgagc tgtaaataaa agcaaagcta
    47941 gtggctaagg tcacaagcga atccatatta ggccgcttct ttatcaatgc cttaaagcca
    48001 ttttcatagt actgccgatt caagaaaaga acaggcaggg tcagcaaaag ctgaacaaga
    48061 ccatagctta tagcatgcga ctgaggtgct agagcgaccg gcagcaccaa tccaagcata
    48121 ggtcccattg caaggtatag cagcggcaga ctaaagagag cagaccacag aaagcgatac
    48181 cattcattgc tagcctgctc ctctaggcgc tctagttgcc ctctcatatt ggtctcatca
    48241 agcagctctg ctctgtagcc tgcctttctt actgcttgaa tgagctctgc tgagctgagg
    48301 ctgtcagttg agtagctcac tgatagcttc tcagtcgtca catcaacagc tgccccctca
    48361 acacctggca gttgcttaac agcctgttca atcgctagag cacaggaggt gcagtgcatt
    48421 ccctctaata gataggtctc tttaacaatc atatcctctc ctttttctga caatgacatt
    48481 gtcctggcac acaatcacac cttacatggg atactgctcc gactttttta gcctctaaga
    48541 gcaactgaaa agcctgaata tcttccaggg tcattggggt atcctttagt aatgccagca
    48601 acaagcggct atggtggcgt tgacacatgc catcaagcct ctctcgtagc atagcaagct
    48661 gtcgcctgtc ctgatcaagc aaggactggt aaatatagga ccgtccctgt ctatcagccc
    48721 ttagggcttt tttcttaacc aagcgtccaa tcaaggtctt aacggtagaa tcagaccaat
    48781 ggtgcttttc atgaagaata gcaataatct cagagctctt catgctccca ttagcccaaa
    48841 caacacgcat aacctcccat tctgcatcag atatcgtatc catattgcta cctctctttc
    48901 atctacggtt ttattaagta tagcttattt gtttacgttt gtaaacaaat aataactaaa
    48961 aaaggtctct ttatgagaaa cagcgtcaaa aaaggactga cagctaaagt cagcagctag
    49021 cttttaatag tctgaacttt ccagtcttat ctgattaact ttatattgac aaaatgagtc
    49081 cttgtatatt actatatgac agtaatactg taatgattaa ggagaaaaca ttgacgtatc
    49141 ttaaaagaca gctaattcta ctagcccttc tactcacagc tataggtagc caaacaatcg
    49201 ttcaggccag cacgcgatcc tggaaaagct ggtttattga gcaatatttt tggcttaaac
    49261 gagacaaaag ctattatgcc gagcaggatg agaatacctt ctacaactac gtcaagtcag
    49321 ctggtgaaaa gagcaatcaa ggctttaatc tcactcaaaa tgaggtcaac ggaacattaa
    49381 agacagagta tagagacaac atgcaggttc acagctggaa tgaaaactct actaatccat
    49441 caaatcaaaa ggtcattctc tatctgcatg gtggctccta cctaaacaac ccgacctcat
    49501 accatattga catgctcaaa accttgtcaa ctagccttga tgctaagatt gtattgccga
    49561 tttacccaaa ggctccgacc tatacctatg atgtcgctat gccaagatta gttagtcttt
    49621 atcaggatat tctaaaaagc actaataaca atgctaacaa tatcaccatc atgggagact
    49681 cagccggagg cggtctggca ctaggtttgg cactagcatt gaaaaatgaa gatattaagc
    49741 agcctaagga cattatcctg ctctcacctt ggcttgatgt caccctatca aatccagaga
    49801 tcccaaatta cgaagcctct gatcctatct tatcggcttg gggactgcgc atagtaggtg
    49861 atatctgggc acgacgcggg gaaaataaca ctaagcaccc ttatgttagc cctatctatg
    49921 gagatacaag caacctagca cctatcacca tgtttgtagg aactcatgaa atcttctacc
    49981 cagacattac aaaatttgat ggtatgttaa aacaaaaagg acataagcac cagctatttg
    50041 tcggggaaaa gatgaaccat gtttatccta tttacccgat tgaagaggcc aagacagcac
    50101 aataccaaat cattgatacc ataaaaaaag agtacgaacc ccaaaaataa taatacaaaa
    50161 atgcctacca gacttgagtt ttttgccaaa gcctggtagg cattttctga tcacagcatg
    50221 actactgttt cttttctagc tcacggagca attgatcaat tttattacca taggcgatag
    50281 aattgtcctt ttcaaaaacc aaatccggaa ttttatacat ggttaattgc ttaccaagct
    50341 cacgcttaat ggttcctgtt gcttttttta agcctatttc agccttttga ttgtctgaag
    50401 ctaggtcact cataatggta tagtaaacct tagcaactga caaatcgccc agcatttgca
    50461 cttctgtgat cgtaacaccc tgcacacgtg gatcacgaac ctttttgtgt aaaatctcgt
    50521 tgacctcacg cttgatttcc ataccaacac gatcaatacg atgatttgtc atggcccttc
    50581 ctttctattg tcaaatagta caggctctca gtagctcaat aacaagagaa aagcttgatg
    50641 actttcaagc ctttttctct attaggctga tggctatact attaatagtg actgttcaaa
    50701 tcaagtggtg acattgtcta ttgtcttgag acgaggctat ttaagctact agccaccacg
    50761 attatttacg ggtaatttct tccatgacgt aagcctcaat ggtatcatcg accttaatgt
    50821 cattaaagcc ttcaatcatc aaaccaccct cttgggcatt cccaatctcc ttaacatcgt
    50881 ccttataatg cttaagactg gctagcttac catcaaagat aaccacgcta tcacgaatga
    50941 cacgtacact tgaatcacgc gttaccttac cattaacaac cataaagcct ccgattgtcc
    51001 caaccttaga gaccttaaag gtttcacgaa taatagcctc accaagcatt ttttcttgat
    51061 actcagggtc aagcttacct ttcatggctt cctcaacctc ttcgatcacc ttataaataa
    51121 tgctatgcaa gcgaatctca acatcgtctg tatcagcctg ctgacgcgcc tgtggtgttg
    51181 gacgcacatt gaagcctatg ataacagcgt ttgaagcctc tgccaaggtc acatctgact
    51241 cattgatcgc accgacagca gagtgaacaa catttactcg aacgccctca acatcaattt
    51301 taaggagtga ggctgccaaa gcttccacag agccctgcac gtctgccttg atgatcacgt
    51361 taacggtttt gatttcccct gccttgaggg tatcaaatag gttatcaagg ctgacacgct
    51421 gcgtgttttg acgttgcttg agaagggcac gcttagcacg ctcctcccct gctgcacgcg
    51481 ctgctttttc atcagcatag accgcaaaat gatcacccgc cataggggtt tcattgagac
    51541 cagtaataga taccggtgtg gacggctcag ctgatttcac acgacgacca aggtcatttg
    51601 tcatggcacg cacacgacca aaggtgttac caacaacgat tgggtcttgt acgtgtaggg
    51661 ttccttgttg gaccagaagt gtcgcaaccg cacccttacc tttgtcaagt ctagcctcaa
    51721 tgaccgtacc aatcgcacga accgtaggat cagcctttag ctcttcaacc tcagctacca
    51781 aaagcactgt ttctagcagc tcatcaatgt ttttgttaaa tttggcagag atttcaacaa
    51841 actcacactc accaccccaa gcagttgaga tgatcccatg ctcagccaat tctgaaataa
    51901 cacgctcagg attagcccct ggcttgtcaa tcttgttgat ggcaacgata attggaacac
    51961 cagccgcctt agaatggtta atagcttcaa tggtttgtgg cattaccccg tcatcagcag
    52021 ctacaatcaa aatggtaata tctgtcactg acgctccacg tgcacgcatg cttgtgaagg
    52081 cagcatgtcc tggtgtatcc aagaaggtaa tcttcttgcc tgcctcctca atctggtaag
    52141 ctccaatatg ctgggtgatc cctcctgctt ctcctgttgc aacacgagaa tttctaaggg
    52201 tatcaagcag ggtcgtctta ccatgatcga cgtgtcccat aatggtaaca accggtgcac
    52261 gctcaacaat attctcagga ttaaggtagc tatcatcagt aaagaagcgc tcgatatcag
    52321 cttcatcaac ctccaccttg gccttagctt caatgccata atccaccatt aagagctcaa
    52381 tggtatcacc atctaaggat tggttttgcg ttgccatcac acccatcata aataatttct
    52441 tgacaatctc agccggctca cgcttgatcc gttttgcaat ttcagcaacg gtcattcctt
    52501 ctgaatattc aaattctttt ggtaattcat ggaatttacg ctctgttact ggttttggag
    52561 ctgtgttgct attcttatga tgcttacctt ttttgttttt cttgttgtta ttccagttac
    52621 tattcttttg atttctcact tggttttgac tattccaact cttcttattt ttcttttgtc
    52681 catcttctag gccatgatcc cgatcatgcc ctttgtctgg acgattttgt tttttacgac
    52741 gcttatcaac cggttttgct accgatgcag cagccatact agcaaccgac tcagtagcct
    52801 tagctgaggc ttcacgatgc tttttgtcct ctgtctgagc cttgagggcg gctgccttag
    52861 cctcttgcct tgcctgttgc tctaagcgtt tagcctcctc ttgctcacga aagcgtgatt
    52921 ccctttgtct ggcatactct gcgttttgct cagcctttaa ggcagcagca cgcgccttaa
    52981 aatcaatctt aggagcaccg gcttgggtct gcccttgacg tcctgtatcc tgttgacgac
    53041 tattagcgtt aaaggaacgg tttttgtcac gattaccagc ttgtctatgc ccatcgtttc
    53101 ggttatttcc agatgatggc ctgttatcaa agcgtctatc tctttgctga ttttgtgact
    53161 tgtggccagc tcgctccgtc tgctgacctt gtgatcgtcc aagttgacga tagtctgact
    53221 tgcggtcatt agagcgattt tgcccagcct gccgtctcgc tacctgctcc ttggcacgtg
    53281 cttcacgctc tgccttgaaa ttgcggctct ttggcttaac agcaaccggc tgtgatgctt
    53341 cttgtgtcgc agcagctggc ttttctgctg ctttagaggc tgctggctgt ggtgtagtgg
    53401 ccttagctgc ttttgctttt tgttctgcta cttgcttgtc ttttgctgaa cctgcttgaa
    53461 cattcttagt cacacctgct gaaaagctag aggcaatttt gttagcatct gcttcttcga
    53521 cgcttgacgc atggcttttg acatctaatc ctaaggattt agcacgctca acgacttctt
    53581 tactactttt gccaatttcc ttggcaattt catgtaatct tttctttgac aatttgtgtc
    53641 ctcctattcg tctatttcat aagagtcctc attttctttg aaaatccagc gtctgcaatg
    53701 gcaaccacct tacgaggctt gccaagtgca gcacttaatt ccagtgcact aaacactgtg
    53761 gagacttcta cattgtaata attactttta tctgttactt ttttagtgat atttgggcca
    53821 gcatcattgg ctaaaaaaac aagattgact tcctgatgtc gaatggcttt aatgaccaat
    53881 tcctcacctg aaatcacttt tttggcccgc tgagccagtc cgatcaaatg agataatcta
    53941 tttaaactat tcaaggccta gctctcttct tttaactttg tgatcaacat gtgcaatcac
    54001 ttcatcgtaa aagctctctg gcacctccat tgagaagcta cgattaaaca cctgtttttt
    54061 ctttgccata agtgcttctt ggttatctag cttgatataa gcaccacgcc cattttgctt
    54121 gccggttgga tcaataaaaa tctgcccctc cttatttttg acaatacgaa ggaggtcacg
    54181 cttatcaatg atctcaccag aaacaagcga cttacgtaaa ggtatttttt ttactttagg
    54241 cataaaacac ctcttttctt acacttcctc gttggttaag agctcctctg tagctactgc
    54301 ttcagtcatt gctgcttctt tttctgcttc aaggcgttca tattcactgg ctgatttgat
    54361 gtcaatgcga tagcctgtca aatgagctgc caaacgaacg ttttgaccac gacgaccaat
    54421 agcaagcgat agcttattat caggcaccac cacagtcgca cgcttaagat cgtcatcatc
    54481 aaagagaacc atatcaacct cagcaggtgc aatggcattg tagataaatt cagcagggtc
    54541 atctacccat tggataacgt caatattttc ttctactggg atctcaagtc ctgtcttagc
    54601 atcatagcgc tttggatgga atttactgat aacctttttg atgttgctgc cgccacgacc
    54661 aacaatcgtt ccaatcgcat caacattggg attgtggcta cgcacagcaa ccttagtacg
    54721 gtcaccagcc tcacgagaaa cactcataat ctcaacggtc ccatcaaaaa cctctggaat
    54781 ttcctgttcc ataatgcgct tgatgaactc agggtgacta cgactaacaa agacgttaac
    54841 cccctttgga ttgttttcca ccttgtagac atagacatca atccgatcat gtgatttgaa
    54901 ggtttctcct gggatttgat cctgatgtga gagctgagcc tctaaggaac caaggttaac
    54961 ataaatgaaa cgttggtcaa aacgctcaac cgtacccgtc atgatttcac cttcatgctg
    55021 cttgtactca ttgaaggtga tttctcgcat ctgacgacgc atcctttcca taatggtttg
    55081 ctttgcagat tgagcagcca cacgtccaaa ctcgctgact gattcttcaa aacgaatctt
    55141 atctcctaac tcataggctg agctaatggc aagggcatcg ttcaggctaa tttccagacg
    55201 gctatcaaat acctcttcaa caacctcacg aaccgtaaaa acctgaaaat ctgctgtttt
    55261 atcattaaat tcaatgacgc aggattctgc ttgaccataa cgacgtttat aagctgattt
    55321 cagtgattca gtgactgcct caatgatatc tgccttatca atgtgttttt cttcttccaa
    55381 aatacggaag gcttctagca tttctttgct cataatgttg tctaccttgc tctcaaagct
    55441 tggtaaaaat cctttcttat cttataaatt aatccattta gggcttagcc aaccgactaa
    55501 agcaaatcgc tcagcaattg ccttataatt tgacagctaa acgagcctta gccactgctt
    55561 ggtaaggaat ctcaactgtt ttgtgacgcg tcttatctag ataatcaatg gttagggtat
    55621 caccatcaaa agccactaaa tctccttgaa aaaccttcac cttatcaatt gcccgataga
    55681 ggctgacatt aatatatgag cctacagcag ccttcaagct ctcagcagtc tttaatggac
    55741 gctctagccc aggactggaa acctccagca tatactgatc tgggaaaggg tctggagaaa
    55801 tcgtatctaa gagtggactg attagctctg taagctcagc agtatcctca acggtaatcc
    55861 cagaagcctt atcaactaag atactaagga cataatcatt gcccattttg tcgtattcga
    55921 tgtcgaccaa ttcatagggt gctttaatta caggttctac gatttgggta acaatatcaa
    55981 taatagctgt gtttgcgatg ttaataacct cctttactga tgactgctat acctctatag
    56041 ccttgtcctc ttgataatca acacaaaagt ggcgagatat ttctcaccac ccttctgtat
    56101 tgctttaacc tattatacca caatcaaaat gaattgcaag aaaatcccta ctaaaagtgt
    56161 caataagacc tcaaaaatcc tattttttaa aaggagagga gatctttaac cttgcttttt
    56221 tctctttcct tatcccctct aacctctgta ttcatatgat aaaataaaat attaaagggt
    56281 aaaaaagaca actaaaatat tatttgcggc tgcttcatgg tctttaccaa aacgaaaaaa
    56341 cctcccatca gaacagatct atgcatatgc gagagaggcc attggtaact caataacatc
    56401 attaataaag cttaaattag ttcaatttgt aattttaata ccactattta tcggtaatat
    56461 aagtttatct gaggatatta aaaatattaa tgctattttt aaagacagca ttagttaatg
    56521 atataataaa agctgtaatc tccctcatta tatcataaaa acgatttcaa aaacagactt
    56581 gtatttcaag tgacatttga tatacttgaa gatgggaata ctgcttgagt ggaggcattg
    56641 taggtctagt tcaacgtaaa gcagcagctg aaatcgcaaa actaatactt aaagtgggga
    56701 tcaagaatgt agcccctgct gcagctgcag catcattaat ttggagcttt ggaagatgca
    56761 tgtggtttta atgtcaaaaa gatatagtat ttgtataaca tttcttgtta ttatttcgcg
    56821 attcgtttgg tttgccctta caggaagaag tcctttttat gactttattg ggactatatt
    56881 tttaggagta gtggttttac taattagtca aaaagtattg aaaaaattaa agtgataaaa
    56941 ttattaaccc gacaatagcg aagcagaatg tgatattatt gatatgttcc ataagatact
    57001 ttctaatgag attgttagtg cttctcatga taagtcttat gggacttttt tgtactcaaa
    57061 aagccctatc atttccatac tggataaatc cactacagaa atgatagagc ctaaaatata
    57121 tgttcaccaa ttggataagt taaaagaaaa aaatgaccat caggtcaaaa gcatttttca
    57181 aaatctcaaa tttgacgggt gaaaaacagg cgaagactcc gaaacccttg atataccaat
    57241 aggataaaag gagaggaggg gattgctggt ggttatttca ccgttttcaa cctttgcaaa
    57301 acacttaaac gttggtgttt tgagaatata aaaaggatag aaaaagacga aaaaacaaaa
    57361 ataaacgggt gattgacggg taatgttact ccaattcccg cagcacttct tccactattt
    57421 cttctattga cacctcccac gacctcactt cctcatgcgg caatacataa tcaaaaatct
    57481 gtccgttttt gcgcacgatc gctactgtgt ctcctgtgat atatccgtca tcaattgcct
    57541 gtttaaattc gtcgtatgtt agcataaagc acctccttat cttattattc gtattttaca
    57601 ggaaataata taattaaatt taaagcttat ttaaaattaa ataacatcta ttttatgaca
    57661 aactaactta ttaactattg acgaatatta gataaaaaga aattttagta caatattggc
    57721 aacaaattaa ttttattaat tttaagtttt tttaatttaa agtggtatac ttaacctgta
    57781 aataattaaa ggaggacatg gatatgtcta aaaagcttag aaactctctc gccagaatag
    57841 ttgttgcagc attcgcatca tttgctgtga tggcgattcc aacttatcat cacagtacag
    57901 tcttagctaa aacagtctca gtaaatcaga cttatggtga atataaagac tattatactg
    57961 taattggtga gtcaaacatt gaccaatctg cttttcctaa gatatataaa acaaccgaga
    58021 gagtctataa aggacaaggt acaagcgaaa aaagagtaac cgtatctgat gtagtttata
    58081 acccattaga tggctataaa cgttcaacag gcgcttacgg cgttgtcaca aaagatatga
    58141 ttgacatgtc taaaggatac cgtgaaaaat gggaaacaaa tcccgaacca agcggttggt
    58201 tcagatttta taatagagcc gataatgaag aaattagtga gaaagaatat gattcaagac
    58261 gtactaagtc atacaaagtt accaacaatg tacctgtagt gttaacaaca ttaaaaggta
    58321 aacaatacaa cagtcactta tttgtacgta gccatctctt tgccgatagc cttggaggaa
    58381 agtccatacg gaaaaacgct attactggaa ctcaaatgca aaatgtagga acacgtaaag
    58441 gtgggatgca atatattgag aaaaaagttt taagccatat cactaagaat cctgatgttt
    58501 atgtattcta cagcgccatc cctgaatatc aggggactga gttattagca agatcagttt
    58561 tagtatctgc tttatcttcc gatggagtaa ttaatgaaac tgttcgtgtt ttcaacaccg
    58621 ctgatggatt taatattaat tatgaaaagg gtggactctt aacagaaagc cctgtaagtg
    58681 aaattgataa tattgaagat tctacaacag acgaaataga aaattctgtg gatgattcag
    58741 aagaaatagt ttataacgat actactaccg aagaagaaga agaaaactaa gatttcaaaa
    58801 aatttttaga cacacaaaaa ccgcccagaa attaatctga gcggttgttt ttttatttaa
    58861 aatagttacc tagcataaag cacaagacac aaattatcaa taaaaagaaa aaatatccgt
    58921 tgttaagaaa tgtattccct atgtgtttta gcttattgcc attacaacta caacagttta
    58981 gtggaatggg tttatcaata attatagata tccaactaag catagagtat attagaatca
    59041 acaaaaatcc taatagaata gacgatatga ctaaagtttt accaattgat acctcagttg
    59101 tactgagagt cccaatcata gttgacaaag cactaaatcc tccaaacata ataaagacaa
    59161 acgacgaaaa tacacccaaa atagttacaa aatcagtata tatttgtgat tttgtttttt
    59221 taaactgttt taattctttt tccgcaactc ttacattttt ttccattctg ttagattgct
    59281 tttctaaatt atctgttgat tttcgtattt gctttaatcc atctctggtg atttttgagt
    59341 tttccactat aaattctttt tgaacttggg caagcatata gttatttttt attttatcaa
    59401 ggttttttat taagatatct ttatcttttg aaccgccttg aaatttagtt acaataaatt
    59461 tgattttatt ttctaaaatc tcattaactt catcgctttg ttcattttca tatacatatt
    59521 ttgcaattct attataaggt atagtcaagt tagaatcgag taaataacga taataaacat
    59581 ctaaagtcga ttttttaata ggatcagcac tattatcttc caagccaccg tccagcaatg
    59641 aatcaataac ttttaatggc attgaaccca tagtttctcc tcgggatgat ttccaaaata
    59701 atctttgatt tcttcaatag tatatttaat tccttgaata ccttccatta ttctatcctc
    59761 atcctttttc caaggtgtgt gtctatgagt aatattaaca agttcaaatg gatcacgatt
    59821 atttagggca gccaccgtat tctcaatcaa tccagtattc tcgacatttt ctggattgta
    59881 ttcggttatt tctaggtcag caaatgggct atggctgaat tcaacatatt ccataatcat
    59941 ctcgtctgta gagatggaaa aagctccaaa acgtttatat tcatgataga catcaggaac
    60001 aactggtcca tacttccact tttccatact ttcttcaaaa agaggagctc cattttcaag
    60061 aatatttctt acattcacga agtataataa tttttgcaat ttaagattat tgattgggta
    60121 gcctttttta tttgaatact caattatata atttgcaaca aataatgcat gcatctcaat
    60181 tacacctcct ttttcttaat tataacatat ttgtcaagta ctatatcttg ttagctaaaa
    60241 aattagctaa cactacatat tgattttgat aacaaaaata cccccgcaaa agcgagggca
    60301 tttgtcttat ctcggagctt tacctcctaa tttaatttcc cccaaaggct gatacggttt
    60361 ccatctttat cagtctgtcc aatcgctagg taattacgct taccagagcc accgacatag
    60421 ctaatccagt agtagccatt agcgtagccc tcgctgtcaa agttaacggt gtcaccttgc
    60481 ttatagctgc ctactacttc gctggcgaga cttggccaac gtctaatgtt aatctctgca
    60541 acatctagcg taaaagtacc tgtttttgga gtctctacga tcgtgtctga ggtttgcggg
    60601 tctgtgctga ccgtttgtgc agcaacatct ccctgataag gaggataaaa ccagccggcc
    60661 acattagtaa agtcacgagt attaaaacgg gccggacccc ctacatacaa cgcatctgca
    60721 ttaccatcaa tattttgctc gatagtctgc atagtgtaac catctgagtc aacgtacaca
    60781 agacccgtat gaccataatt gataccacca aaccaagcgt ccatgacaaa aaatgcccca
    60841 gctcgtggat ttgcatctgt aggcatgcga tggacttccc agccctgcgc acttgcgcta
    60901 tctagtaagt ccgctgcgtt gccccagaga tcgacaccaa accagtgctt agctgcgtaa
    60961 caagggacat ctgcacattg cgtgccataa gccccgtcct tatcaacacc cataccagca
    61021 ttagccaaat tgatgtaaaa ctcgataacc tctcgacact gcgaactaat catttgtgac
    61081 tcctttcttt ttgctagggc ttccgcgtcc catttttgta ggtcgttttg ctctattagt
    61141 tggataagca gctc
//
LOCUS       DARYNN010000004        60752 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.004, whole genome shotgun sequence.
ACCESSION   DARYNN010000004 DARYNN010000000
VERSION     DARYNN010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 60752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 60752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60752
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.004"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(<1..191)
                     /locus_tag="TVB59_000194"
     CDS             complement(<1..191)
                     /locus_tag="TVB59_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEL1009141.1"
                     /translation="MSQTYERIMVAIDGSHGSELAFHKGVNVALRNGAALILTHVVDT
                     RALQSVATFDSYIYDKLEQ"
     gene            478..1692
                     /locus_tag="TVB59_000195"
     CDS             478..1692
                     /locus_tag="TVB59_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEL1009142.1"
                     /translation="MKIIEKSSKLEHVAYDIRGPVLDEANRMIANGEKILRLNTGNPA
                     AFGFEAPDEVIRDLILNARSSEGYSDSKGIFSARKAIMQYCQLKGFPDVDIDDIYLGN
                     GVSELISMSLQALLDNGDEVLVPMPDYPLWTACVSLGGGHAVHYLCDEEAEWYPDIAD
                     IKAKITERTKAIVIINPNNPTGALYPREVLEEIVAIAREHQLIIFADEIYDRLVMDGG
                     EHIAIASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKRHVRGYIEGLNMLANMRL
                     CSNVLAQQVVQTSLGGRQSVDELLLPGGRIFEQRNFIYQAINAIPGLSAVKPKAGLYL
                     FPKIDRNMYRIDDDEEFVLQLLKQEKVMLVHGRGFNWKEPDHFRVVYLPTVEELADVQ
                     EKITHVLKQYKR"
     gene            1864..2646
                     /gene="codY"
                     /locus_tag="TVB59_000196"
     CDS             1864..2646
                     /gene="codY"
                     /locus_tag="TVB59_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001133183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEL1009143.1"
                     /translation="MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNAC
                     IINGGGSLLGYAMKYKTNTDRVEEFFETRQFPDAYVKAASRVYDTEANLSVENELTIF
                     PIESKDIYPDGLTTIAPIYGGGMRLGTLIIWRNDNEFSDDDLVLVEISSTVVGIQLLN
                     LQTENLEETIRKQTVVNMAINTLSYSEMKAVAAILSELDGNEGRLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVINEGIFDKLKEF"
     gene            3263..3820
                     /locus_tag="TVB59_000197"
     CDS             3263..3820
                     /locus_tag="TVB59_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEL1009144.1"
                     /translation="MKALISIDYTNDFVADDGSLTAGAPAQVISEAMASVVEAAFEAG
                     YYIFFAIDAHEEGDSFHPEAALFPPHNIIGTRGRDLYGPLMTVYTRYQQDQRVFWLDK
                     RHYSAFSGTDLDIRLRERGVTTLVLTGVLTDICVLHTAIDAYKLGYKLEIITSAVASN
                     STENHQWALNHCRTVLGAKLLDRLS"
     gene            4294..4596
                     /gene="gatC"
                     /locus_tag="TVB59_000198"
     CDS             4294..4596
                     /gene="gatC"
                     /locus_tag="TVB59_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008086915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEL1009145.1"
                     /translation="MKISEEEVRHVAALSKLSFSESETTEFATTLSKIVDMVELLNEV
                     DTTGVAITTTMADKKNIMRADIAEAGVDRKLLFQNVPEKENHFIKVPAILDDGGDA"
     gene            4596..6062
                     /gene="gatA"
                     /locus_tag="TVB59_000199"
     CDS             4596..6062
                     /gene="gatA"
                     /locus_tag="TVB59_000199"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEL1009146.1"
                     /translation="MSFNHHTIEELHELLVAKDISAVELTKATLEDIKAREEAVGSFI
                     TIACEAALKQAAALDAKGIDPDNVMSGIPLAVKDNISTKGILTTAASKMLYNYEPIFD
                     ATAVANAYDKDMIVIGKTNMDEFAMGGSTETSYFKKTKNAWDHSRVPGGSSGGSATAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGVVGLKPTYGAVSRYGLIAFGSSLDQIGPFAPTV
                     RENAQLLSVIAGSDRKDSTSAPVQIADYTIKIGQDIKGMKIALPKEYLGEGIDPKIKE
                     TVLAAAKHFEKLGAIIEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGFRAADA
                     KSLEDIYVKTRSQGFGDEVKRRIMLGTFSLSSGYYDAYFKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPTAAFELDTLNHDPVAMYLADLLTIPVNLAGLPAISIPAGFADGLPVG
                     LQLIGPKYSEEVIYQVAVAFEATTDYHKQQPMIFGGDR"
     gene            6062..7501
                     /gene="gatB"
                     /locus_tag="TVB59_000200"
     CDS             6062..7501
                     /gene="gatB"
                     /locus_tag="TVB59_000200"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEL1009147.1"
                     /translation="MNFETIIGLEVHVELNTNSKIFSPSSAHFGEDPNASTNVIDWSF
                     PGVLPVMNKGVIDAGIKAALALNMSIHQHMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIDITLEDGSTKKIRIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEIIQYTGISDVKMEEGSMRVDANISLRPYGQEAFGTKTELKNLNS
                     FSNVRKGLEFEVERQAKILRSGGVIRQETRRYDEASKGTILMRVKEGAADYRYFPEPD
                     LPLFEIDDAWIEDMRAELPRFPADRRASYINALGLSAYDAGQLTATKALSDFFEQAVA
                     LGGDPKQVSNWLQGEMAQFLNAEGKTIDQIALTPENLVEMIAIITDGTISSKIAKKVF
                     VHLAKHGGSARAYVEKAGLVQISDPAVLIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQIAQQLLAQELQKLLD"
     gene            7730..8674
                     /locus_tag="TVB59_000201"
     CDS             7730..8674
                     /locus_tag="TVB59_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEL1009148.1"
                     /translation="MSRNGKGSTMILLAGIAWGLSGVSGQYLIAHGVGINALTSLRLI
                     ISGLVLSAMAYVRQREAVISLLKDKRLLRELLIYSLFGLTLNQYAYLLAIRYSNAGTA
                     TVLQYLSPILVLVYLSFKSRRLPAVGESCAICLAILGTVIMACHGDLSHLAINPIGLF
                     WGLFAAVTYAYCVIKPAKLIADWGSLLIVGLAMLMGGVIFPILTRAWQYPLAMTYGNL
                     RALFGIIGIGTIFAYTFFLKGASIIGPIKATLLASIEPVASVCFAIILMKEIFHPIDL
                     LGMALILIAVLVISLRDLLLTKRKKQLALNIKRPPSSD"
     gene            8725..8964
                     /locus_tag="TVB59_000202"
     CDS             8725..8964
                     /locus_tag="TVB59_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEL1009149.1"
                     /translation="MVWSLIVGAIIGMVAGRITEKSHSMGCFTMTAAGLIGSAVGQKL
                     FGDWGIQLAGMAVFPSILGAAIVIIVASALFGKKQ"
     gene            9161..10276
                     /locus_tag="TVB59_000203"
     CDS             9161..10276
                     /locus_tag="TVB59_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KxYKxGKxW signal peptide domain-containing
                     protein"
                     /protein_id="HEL1009150.1"
                     /translation="MRKTEGRFRTWKSKKQWLFAGAVVTSLLLGAALVFGGLLGSLGG
                     SSHQARPKEQPVSSIGDDDKSHKSSSDSMVSRPPKKDNLQPKPSDQPTNHQHQATSPS
                     QPTAKSSGHHGNQPQSLSVNSQGNSSGQASEPQAIPNQGPSQPLGLRGGNSSGSGHHH
                     QPQGKPQHLDLGKDNSSPQPQPKPQGNSPKLPEKGLNGENQKEPEQGERGEAGPPLSG
                     LSGNNQGRPSLPGLNGENQKEPEQGERGEAGPPSTPNLEGNNRKNPLKGLDGENKPKE
                     DLDGKGLSGENDESPKLKDEHPYNHGRRDGYRVGYEDGYGGKKHKGDYPKRFDESSPK
                     EYNDYSQGYNDNYGNGYLDGLADRGGKRGYGYSYNPD"
     gene            10540..10806
                     /locus_tag="TVB59_000204"
     CDS             10540..10806
                     /locus_tag="TVB59_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003067640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEL1009151.1"
                     /translation="MKAIITVVGKDNQGIVAGVSGQIAALGLNIDDISQTVLDDYFTM
                     MAIVSSSEKQDFAHLREVLQAYGKQLQVTINIQSAAIFDAMHNI"
     gene            10821..12158
                     /locus_tag="TVB59_000205"
     CDS             10821..12158
                     /locus_tag="TVB59_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEL1009152.1"
                     /translation="MDIRQVRETVEMIEEQHFDIRTITMGISLLDCIDSDIDRAAAKI
                     YQKITTKAANLVAVGDDIAAELGIPIVNKRVSVTPIALIGAATDAEDYLSLAKALDQA
                     ACDIGVDFIGGFSALVQKGYQKGDKILIESIPQALAQTQKVCASVNVGSTRSGINMTA
                     VADMGRIIKETAKASEIGAAKLVVFANAVEDNPFMAGAFHGVGEADTVINVGVSGPGV
                     VKRALEKVRGESFDVLAETVKKTAFKITRIGQLVGQMASERLGVGFGVVDLSLAPTPA
                     VGDSVARVLEEMGLEIVGTHGTTAALALLNDAVKKGGVMACNRVGGLSGAFIPVSEDE
                     GMIAAVQGGSLNLEKLEAMTAICSVGLDMIAIPEETPSETIAAMIADEAAIGVINQKT
                     TAVRIIPKGKEGDMIAFGGLLGTAPVMAVNPHSSADFIARGGQIPAPIHSFKN"
     gene            12233..12940
                     /locus_tag="TVB59_000206"
     CDS             12233..12940
                     /locus_tag="TVB59_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEL1009153.1"
                     /translation="MTKTRLYIVRHGKTMFNTIGRAQGWSDTPLTKAGEEGIRELGLG
                     LKAAGIPFKAAFSSDSGRTMQTMEIILRKSENEFLPYTRDKRIREWCFGSLDGAYDSE
                     LFLGVLPRTKAFENRDNLRDVPYSELAESIVEVDTANWAEPWEVLSKRIYEGFEAIAL
                     AVENAGGGNAIVVSHGMTIGTFMWLIDPDREKQYIDNGSVTVVEYENGQFTIKTIGDM
                     SYRYRGREIIESIRDEE"
     gene            12930..13673
                     /locus_tag="TVB59_000207"
     CDS             12930..13673
                     /locus_tag="TVB59_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HEL1009154.1"
                     /translation="MKNNTIRVLLQALVVLLFLSGVYLFIKPEKQAVGPKANQTVPAP
                     KAAKQAKKTTDLPKVSTTDWQLVLVNRDHPQEEMSPELVEINGIPIDKRIEQETADFL
                     AAAQTIEPQEHLIAGYRSVVQQEELYQSYIAQELANDPSLTQEAAEALVRKYAQPAGT
                     SEHQTGLAIDMSTVDNLNASDPKVAQEIQKIAPQFGFILRYPKGKQTSTGIEYEDWHY
                     RYVGKASALYITAHSLSLEEYLTRLKEKK"
     gene            13670..14242
                     /locus_tag="TVB59_000208"
     CDS             13670..14242
                     /locus_tag="TVB59_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEL1009155.1"
                     /translation="MRKRLKFSYFLVFLVFIMVALIGPLLFNAKGTSASQEMSVPYTE
                     RQFIQLVAKEVKPLAKNYGIRPSILIGQIILETNYGRTLLAAKYHNLFSLQPAPGQAS
                     ISLKKQAASKHKTAYAIYRDREDSIRAYLSWLSQGTGEEKKLYQSLATEKGYKKPAKS
                     LQTYRYSDDKGYAQRLVQLIEARGLTSYDD"
     gene            14692..15726
                     /gene="hrcA"
                     /locus_tag="TVB59_000209"
     CDS             14692..15726
                     /gene="hrcA"
                     /locus_tag="TVB59_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015911815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEL1009156.1"
                     /translation="MITERQSNILNLIVDLFTQTHEPVGSKALQSLIASSSATIRNDM
                     AKLEKLGLLEKAHTSSGRMPSAAGFKYFVEHSLNLGSIDEQDLYQLVKAFDFEAFKLE
                     DVLLRASQMLSDTTGYTAAILDVEPARQRLTGFDIVQLSSHDALAVLSLDESKPLTVQ
                     FAIPKNFMNRDLLVLKGIVADRLLGKDVMTVHYKLRTEIPQIVQKYFTVTDNVLDLFD
                     YIFVGLFRETIFVSGKVAALDYAGLATYQFLDEEQRLALSIRQSLSEEEMATVQVADS
                     SEPALANVTLLTYKFLIPYRGFGLLSLIGPVDMDYRRSVSLINVIGQLLAVKLRDYYR
                     YLNSNHYEVH"
     gene            15771..16340
                     /gene="grpE"
                     /locus_tag="TVB59_000210"
     CDS             15771..16340
                     /gene="grpE"
                     /locus_tag="TVB59_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEL1009157.1"
                     /translation="MSKKPKEELKDQEDILDEAAEEAVEPVEEADQSAELIADEAAEE
                     PSELELALQRAEDFENKYLRAHAEMQNIQRRANEERQSLQRYRSQDLAKKILPSLDNL
                     ERALAVEGLTDDVKKGLEMVQESLVQALKEEGIEEVPVEAFDHNLHMAVQTLPADDDH
                     PADSIAQVFQKGYKLHERLLRPAMVVVYN"
     gene            16745..18574
                     /gene="dnaK"
                     /locus_tag="TVB59_000211"
     CDS             16745..18574
                     /gene="dnaK"
                     /locus_tag="TVB59_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEL1009158.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVAANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLATAGDNKLGGDDFDQKIIDFLVAEFKKEN
                     GIDLSQDKMALQRLKDAAEKAKKDLSGVTQTQISLPFITAGAAGPLHLEMSLSRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQHIVIKSNDGLSEEEIERMMKDAEANAEADAKRKEEVDLKNE
                     VDQAIFATEKTIKETEGKGFDTERDAAQTALDELKKAQESGDLDDMKAKLEALNEKAQ
                     ALAVKMYEQAAAAQQAQAGAEGAADTGSTNSGDDVVDGEFTEK"
     gene            18731..19867
                     /gene="dnaJ"
                     /locus_tag="TVB59_000212"
     CDS             18731..19867
                     /gene="dnaJ"
                     /locus_tag="TVB59_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015911812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEL1009159.1"
                     /translation="MNNTEYYDRLGVSKDASADDIKRAYRKMSKKYHPDINKEPGAEQ
                     KYKDVQEAYETLSDSQKRAAYDQYGAAGANGGFGGGAGGFGGFDGGGFGGFEDIFSSF
                     FGGGGMRNPNAPRQGDDLQYRVNLSFEEAVFGTEKEVSYHRESTCSTCAGSGAKPGTS
                     PTTCRKCHGSGVINVDTQTPLGMMRRQVTCDVCHGSGQEIKEPCHTCHGTGHEKKVHK
                     VSVKIPAGVETGQQIRLQGQGEAGFNGGPYGDLFVILNVLPSKQFERNGSTIYYSLNI
                     SFVQAALGDTVDIPTVHGDVAMSIPAGTQTGKVFRLKGKGAPKLRGGGQGDQHVTVNI
                     VTPTKLNEAQKEALKAFAEASGEKPIAPKKKGFFDKVKDALEDI"
     gene            20187..20978
                     /locus_tag="TVB59_000213"
     CDS             20187..20978
                     /locus_tag="TVB59_000213"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEL1009160.1"
                     /translation="MTFQNIIFELEEDLAILTLNRPEVSNGFNIPACQEILEAIRLVK
                     DNPSLRFLVIKAKGKVFSVGGDLVEMQNAVERDDVQSLVRIAELVQDISFAIKQLPKP
                     VILCADGAVAGAAFNIALAVDFCIASTQTKFIQAFVNVGLAPDAGGLFLLTRAVGLNR
                     ATHLVMTGEGVTAEKGLEYGFVYRAAESDKLDKTCSQLLKRLRRGSSNSYAGMKSLVW
                     QSFFAGWEDYAQKELAIQEELAFKEDFKEGVRAYGDRRRPNFRGK"
     gene            21058..21492
                     /locus_tag="TVB59_000214"
     CDS             21058..21492
                     /locus_tag="TVB59_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEL1009161.1"
                     /translation="MEYNKINQYLVDIFNRILVIEEMSLKTSQFNDVSLKEMHTIEII
                     GKYQQVTPSDIARELMVTLGTVTTSLNKLELKGYIERTRSSVDRRVVYLSLTKKGRLL
                     DRLHARFHKNMVGHVIADMNEDEMQALLRGLGNLHQFLEDLV"
     gene            21492..22466
                     /locus_tag="TVB59_000215"
     CDS             21492..22466
                     /locus_tag="TVB59_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEL1009162.1"
                     /translation="MVFSKISQVAHYTPKQVISNDDLSQIMDTSHEWISSRTGIEKRH
                     ISTVEMTSDLAIRVAEQLLAGSGYDATALDFIIVATISPDASMPSTAAKVQAAIGATN
                     AFAFDMTAACSGFVFALAMADKLIASGAYQRGLVIGAETLSKIIDWQDRSTAVLFGDG
                     AGGVLLEASEQQHFLAEALHTDGAQGQSLTSGQSSLRSPFSQGQEVNSFLQMDGRAIF
                     DFAIRDVSRSITAIIEQSGLAKEELDYLLLHQANRRILDKMAKKIGMPREKFLENMMH
                     YGNTSAASIPILLSESVQNGQLKLDGSQHILLSGFGGGLTWGSLIVKI"
     gene            22524..22748
                     /locus_tag="TVB59_000216"
     CDS             22524..22748
                     /locus_tag="TVB59_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEL1009163.1"
                     /translation="MAVFEKVQEIIVEELGKDAEEVTLETTFDDLDADSLDVFQVISE
                     IEDAFDIQIETEEGLNTVGDLVAYVEEKTK"
     gene            22943..23929
                     /gene="fabK"
                     /locus_tag="TVB59_000217"
     CDS             22943..23929
                     /gene="fabK"
                     /locus_tag="TVB59_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEL1009164.1"
                     /translation="MKTRITELLNIDYPIFQGGMAWVADGDLAGAVSNAGGLGIIGGG
                     NAPKEVVKANIDRVKAITDKPFGVNIMLLSPFADDIVDLVIEEGVKVVTTGAGNPGKY
                     MERLHEAGIIVIPVVPSVALAKRMEKLGVDAVIAEGMEAGGHIGKLTTMTLVRQVVDA
                     VSIPVIAAGGIADGRGAAAAFMLGAEAVQVGTRFVVAKESNAHQSFKDKILKAKDIDT
                     VISAQVVGHPVRSIKNKLTSAYAKAEKEFLADRKAASDIEEMGAGALRNAVIDGDVIN
                     GSVMAGQIAGLIRAEESCEAILKDIYYGAAAVISQEAKRWQALAADDKNETI"
     gene            23942..24862
                     /gene="fabD"
                     /locus_tag="TVB59_000218"
     CDS             23942..24862
                     /gene="fabD"
                     /locus_tag="TVB59_000218"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEL1009165.1"
                     /translation="MTKTAFLFAGQGAQTLGMTRDLYDQYAIARDTFDQASQLLGYDL
                     RKLIDTDQDRLNQTAYTQPAILTASVSIYRILTSYGVHPDMVAGLSLGEYSALVAAGV
                     LSFETALELVAKRGRFMEEAAPAGSGKMVAVMNTEARLIEEACQEASSVGVVSPANYN
                     TPGQIVIGGTAEAVNAALEILKAKGVKRLIPLNVSGPFHTALLAPASQRLAEELSKIQ
                     FQDFDLPLVGNTEAKVMEKDRIAELLARQVMEPVRFYDSIEVMKANGITQFVEIGPGR
                     VLTGFIKKIDKKLLCSSVEDMPSLQLYLGK"
     gene            24879..25613
                     /gene="fabG"
                     /locus_tag="TVB59_000219"
     CDS             24879..25613
                     /gene="fabG"
                     /locus_tag="TVB59_000219"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEL1009166.1"
                     /translation="MEIKGKNVFITGSTRGIGLAMAHQFAGLGANIVLNGRSAISDEL
                     VETFKDYGVKVVPISGDVSEGADAKRMVDEAIEQLGSVDILINNAGITNDKLMLKMSE
                     EDFERVLKINLTGAFNMTQSVLKPMTKARQGAIINVSSVVGLTGNIGQANYAASKAGL
                     IGFTKSVAREVAARGIRVNAIAPGFIESDMTGVLSEKMQEQILNQIPMKRIGKGQEVA
                     QAASFLASQDYITGQVLAIDGGMTMQ"
     gene            25629..26861
                     /gene="fabF"
                     /locus_tag="TVB59_000220"
     CDS             25629..26861
                     /gene="fabF"
                     /locus_tag="TVB59_000220"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEL1009167.1"
                     /translation="MTLNRVVVTGYGVTSPIGHTPEEFWSSLKAGHIGIKPITKFDTS
                     DFAVKNAAEIQDFPFDKYFVKKDLNRFDMYSLYALYAATEAIEHAGLDIEAIDSDRFG
                     VIVASGIGGIQEIEEQVIRLHEKGPKRVKPMTLPKALPNMAAGNVAMKLNAQGVCKSI
                     NTACASSNDAIGDAFRTIKFGLQDVMMVGGSEAAITKFAIAGFQSLTALSTTEDPSRS
                     SIPFDKDRNGFIMGEGSGMLVLESLEHAQKRGATILAEIVGYGNTCDAYHMTSPHPEG
                     LGARKAINLALQEAGIDAAAIDYVNAHGTSTPANEKGESQAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIATIEAIRHNYVPMTAGTKELSDDIEANVIFGQGKEADIRYAMSN
                     TFGFGGHNAVLAFKRWED"
     gene            26863..27336
                     /locus_tag="TVB59_000221"
     CDS             26863..27336
                     /locus_tag="TVB59_000221"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEL1009168.1"
                     /translation="MNIQEIKDLMAQFDASSLREFSFKSSDGELLFSKNEHRPMAAPA
                     PEPVTLHQEVAPISLTQEIVSKQESIPASSGLQEPEGEVVDSPLVGVAYLAAGPDKPP
                     FVTVGDSVKKGQTLLIVEAMKVMNEIPAPCDGIVTEILVANEDVVEFGQGLVRIK"
     gene            27333..27755
                     /gene="fabZ"
                     /locus_tag="TVB59_000222"
     CDS             27333..27755
                     /gene="fabZ"
                     /locus_tag="TVB59_000222"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002922202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEL1009169.1"
                     /translation="MMDIKQIQEALPHRYPMLLVDRILEASDDEIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKEENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTARFIKRRGTIAVVEAKAEVDGKLAASGTLTFAFGQ"
     gene            27789..29153
                     /gene="accC"
                     /locus_tag="TVB59_000223"
     CDS             27789..29153
                     /gene="accC"
                     /locus_tag="TVB59_000223"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEL1009170.1"
                     /translation="MFNKILIANRGEIAVRIIRAARELGISTVAVYSEADREALHTIL
                     ADQAICIGPSRSKESYLNMNSVLSAAVVTGAQAIHPGFGFLSENSKFVTMCEEMNIKF
                     IGPSGAVMDKMGDKINARAEMIKAGVPVIPGSDGEVYNAQEALEIARQIGYPVMLKAA
                     AGGGGKGIRKVESEADLEAAFNAASQEALGAFGNGAMYLEKVIYPARHIEVQILGDSQ
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGTTLRQRMGEAAVRAAKAVSYENAGTIEF
                     LLDEASGDFYFMEMNTRVQVEHPVTEFVTGVDIVKEQLRIAAGLPLSVRQEDIVITGH
                     AIECRINAENPSFNFAPSPGKITDLYLPSGGVGLRIDSAVYSGYTIPPYYDSMIAKII
                     VHGDNRFDALMKMQRALFELEIEGIMTNIDFQMDLISDKQVIAGDYDTSFLMETFLPS
                     YNKD"
     gene            29162..30028
                     /locus_tag="TVB59_000224"
     CDS             29162..30028
                     /locus_tag="TVB59_000224"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEL1009171.1"
                     /translation="MALFSKKDKYIRITPNNSLKSSVSRNVPEVPDELFAKCPACKHM
                     IYQKDLGPAKICPTCSYNFRISAQERLTLTVDEGSFQELFTDIETKDPLRFPDYQAKL
                     QKARQATGLHEAVLTGTALVKGQRLALAIMDSHFIMASMGTVVGEKITRLFELAISER
                     LPVVIFTASGGARMQEGIMSLMQMAKVSAAIKKHSNAGLFYLTILTDPTTGGVTASFA
                     MEGDMIIAEPQSLVGFAGRRVIETTVRENLPDDFQKAEFLKEHGFVDAIVKRTDLRDR
                     IAHLVAFHGGVS"
     gene            30025..30795
                     /locus_tag="TVB59_000225"
     CDS             30025..30795
                     /locus_tag="TVB59_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEL1009172.1"
                     /translation="MTDVARILKEARDQGRMTALDYASLIFDEFMELHGDRQFADDGS
                     IVGGIAYLADQPVTVIGIQKGKNLQDNLARNFGQPHPEGYRKALRLMKQAEKFGRPVI
                     TFINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADQ
                     VWMLENTMYAVLSPEGFASILWKDGSRATEAAELMKITAAELYQMGVIDRIIPERGYF
                     SSEIVEMIKSHLIDEITQLQAKPLEELLDQRYQRFRKY"
     gene            complement(31027..32304)
                     /gene="serS"
                     /locus_tag="TVB59_000226"
     CDS             complement(31027..32304)
                     /gene="serS"
                     /locus_tag="TVB59_000226"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEL1009173.1"
                     /translation="MLDLKRIRTDFDTVAAKLKTRGVSEAILTSLKALDEQRRTLLVQ
                     TEELKAQRNIASAAIAQAKRQKEDASQQIADMQQLAANIKAIDAKLADIDQEITGIIT
                     VLPNTPHDSVPIGADEEDNVEIHRWGKPRQFDFDIKAHWDLGEALDILDWERGAKVTG
                     ARFLFYKNLGARLERALYNFMLDEHLKEGYQEIIPPYMVNHDSMFGTGQYPKFKEDTF
                     ELDGTNFVLIPTAEVPLTNYYRGDIIDGKELPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPETSYEELEKMTANAEHILQKLKLPYRVLALCTGDMGFSAAKTY
                     DLEVWIPAQNTYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEVLRPYMGGLEVIKPR"
     gene            32904..33956
                     /locus_tag="TVB59_000227"
     CDS             32904..33956
                     /locus_tag="TVB59_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HEL1009174.1"
                     /translation="MTLDKNRHYGLDLLRIISMFMIVITHVLGKGGLRSTVEGEADSY
                     FIVTWMIQVLVYGAVNCYALISGYVGIKSPYKYSKIVNIWVQVFFYSFLMTLLFALFG
                     FPVSLENWRQALFPIVSGNYWYITAYFGLLIFMPMINGGLNTLSNKQLGRLVLLVFAI
                     FSLIPALMNQQVDEFSLSKGFEMTWLIILYIIGAYLRRIELSRFSHKLLIAVYMGSLV
                     VTYIMKFMVGNIWYWYVSPSLTLGAIALFILFAKLKLTSETLLLRFIVIVSPTTLGIY
                     LVHLHPLLVKFIIRDFAEPFVNAPILLYPLLIFGVGIVIYFLSFLVEQARLMLFKKLG
                     FQNLLKWVDKKIPFAD"
     gene            complement(34277..34660)
                     /locus_tag="TVB59_000228"
     CDS             complement(34277..34660)
                     /locus_tag="TVB59_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEL1009175.1"
                     /translation="MAQSLNQRVILQTTAVSYLGIGGKVGKILLGDKALEFYNDKNVE
                     DFIQIPWTAINQIGANVSGKKVSRHFEIFTDQGKFLFASKDSGKILKVARETIGNDKV
                     IKLPTLVQTIIAKLFHHQKKDKKSH"
     gene            complement(34794..35705)
                     /locus_tag="TVB59_000229"
     CDS             complement(34794..35705)
                     /locus_tag="TVB59_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEL1009176.1"
                     /translation="MTEQIKLTKADRKRVWWRSQFLQGSWNYERMQNMGWAYALIPAL
                     KKLYTTKEDRAAALERHMEFFNTHPYVAAPIIGVTLALEEERANGTAIDNAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGALGASLAQTGNLVGPLLFFFGWNIIRMAFLWYTQE
                     FGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVSINFTINLPGKQLSEGA
                     YVVFPEGAVKGAELKSILGQAMGGMSLDKVQSQTLQGQLDSLIPGLAGLLLTFLCMWL
                     LKKKVSPIAIIIALFAFGIIAHLLHIM"
     gene            complement(35721..36530)
                     /locus_tag="TVB59_000230"
     CDS             complement(35721..36530)
                     /locus_tag="TVB59_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEL1009177.1"
                     /translation="MSDISLISAILVVIVAFFAGLEGILDQFQMHQPLVACTLIGLVT
                     GHLEAGVMLGGTLQMLALGWANIGAAVAPDAALASVAAAIIMVKGGDFTQKGITFAYS
                     TAIPLAVAGLFLTMIVRTISTVLVHAGDKAALEGNFSAIERFHFAALLLQGLRIAVPA
                     ALLVAVPTEAVQSVLKAMPAWLNEGMQIGGAMVVAVGYALVINMMATREVWPFFALGF
                     ALAAVTQLTLIAMGVIGVAIAFIYLNLSKQGGNGGGRAGSADPIGDILEDY"
     gene            complement(36701..37693)
                     /gene="manX"
                     /locus_tag="TVB59_000231"
     CDS             complement(36701..37693)
                     /gene="manX"
                     /locus_tag="TVB59_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEL1009178.1"
                     /translation="MGIGIIIASHGKFAEGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYGHFNNAIAQFDADDEILVLADLWSGSPFNQASRVAGENPDRKMAIITGLNLPMLIQ
                     AYTERLMDANAGVEQVAANIIKESKDGIKALPEELNPVEEASTANGGGQALQGAIPKG
                     TVIGDGKLKINLARIDTRLLHGQVATAWTPASKADRIIVASDSVAKDELRKQLIKQAA
                     PGGVKANVVPINKLIEASKDPRFGNTHALILFETVQDALRAIEGGVEIKELNVGSIAH
                     STGKTMVNNVLSMDKDDVAAFEKLRDLGVSFDVRKVPNDSKKNLFELIQKANVQ"
     gene            complement(38045..38856)
                     /locus_tag="TVB59_000232"
                     /pseudo
     CDS             complement(38045..38856)
                     /locus_tag="TVB59_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983364.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
     gene            39115..40575
                     /locus_tag="TVB59_000233"
     CDS             39115..40575
                     /locus_tag="TVB59_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEL1009179.1"
                     /translation="MEKFFKLKENGTTVSTELMAGVTTFFAMSYILFVNPSILSAAGM
                     PSQAVFLATIIAAAISTLIMGLFANVPYALAPGMGLNAFFTYTVVFSLGFSWQEALAI
                     VFLCGLFNIFITVTKLRKSIIKAIPVSLQHAIGGGIGVFVAYLGFKNANLITFSLSSA
                     EIVTVNGVEPAKATAETFANGVFSVNANGGVVPAISTFTDPSVLLAVFGLLLTAVLVL
                     KNVRGAILIGITVTTLAGIPIGVVDLSAVNFADNHISSAFAELGTTFLAAFGGMASLF
                     SDSSRLPLVLMTIFAFSLSDTFDTIGTFVGTGRRTGIFSEEDERALENSSGFSSKMDR
                     ALFADAIGTSIGALFGTSNTTTYVESAAGIAEGGRTGLTAVSTAVCFVLSVLLLPIVG
                     IVPAAATAPALIIVGVMMVSSFLDVDWSDFDVALPSFFAAFFMALCYSISYGVAGSFI
                     FYCLVKLVKGKTKEIHPILWGATFLFVLNFIILALL"
     gene            40941..41384
                     /gene="tsaE"
                     /locus_tag="TVB59_000234"
     CDS             40941..41384
                     /gene="tsaE"
                     /locus_tag="TVB59_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEL1009180.1"
                     /translation="MFYSKNENELIAYGQGIGRQLKAGDVLVLTGDLGAGKTTLTKGV
                     AKGLGIDQMIKSPTYTIAREYEGRLPLYHLDVYRIGDDPDSIDLDDFIFGGGVTVIEW
                     GELLAKGTLHDYLEILITKTETGRQVDYLAHGHRSEALLEELKHV"
     gene            41377..41904
                     /locus_tag="TVB59_000235"
     CDS             41377..41904
                     /locus_tag="TVB59_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1009181.1"
                     /translation="MSEQVVTIEEAKASDASALITLIKEAADETDFITGTEDVIAATV
                     EVLECFLEASQESLTDICLLLKVGDILAGLLNIAGKAYRETSYVGDCFMLVLKPYRNH
                     GLGQLLMETTLDWARETKQLCALELEVQARNTCAYHIYEKYGFKIEGVKRKDVKSRNG
                     DYQDVYLMRKYLERE"
     gene            41905..43167
                     /locus_tag="TVB59_000236"
     CDS             41905..43167
                     /locus_tag="TVB59_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEL1009182.1"
                     /translation="MKIGKKIFLMLTAIVLLTLGAMGVYLTNAYTFSTGELSKTFKDF
                     ATSSKKSDAIQQTEPFSILLMGVDTGSSHRTSTWQGNSDSMILVTINPKTKKTTMTSL
                     ERDILITLSGPNDNEMNGAEAKLNAAYAAGGAQMAIMTVQDLLNITIDKYVQINMQGL
                     IDLVNAVGGITVTNEFDFPISIADNEPEYQATVAPGTHKINGEQALVYARMRYDDPEG
                     DYGRQKRQREVIQKVLKKILALNSISSYRKILSAVSGNMQTNIEISSRTIPNLLGYTD
                     ALKNIKTYQLKGEGATLSDGGSYQIVTSDHLLEIQNRIRAELGLEKLSQLKTTATVYE
                     NLYGSLKTQSTQDSSYYYNSGSLPAYTDSSTQYSTYSSETSSSSSYQDTTAGTQESGA
                     ANVTPSPQADSPAEQQSSGATTGTPAAP"
     gene            complement(43337..43633)
                     /locus_tag="TVB59_000237"
     CDS             complement(43337..43633)
                     /locus_tag="TVB59_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HEL1009183.1"
                     /translation="MTLKTMTTIGLTSVLAYQVYRKRHQIKETLVAMQTSKKAIQADV
                     DRIKANLAIIQKEARTLQAAGTELAYKWQAFNQEAQAHLTEIQQRMSKYQQETP"
     gene            complement(43630..44049)
                     /locus_tag="TVB59_000238"
     CDS             complement(43630..44049)
                     /locus_tag="TVB59_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003108095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEL1009184.1"
                     /translation="MENCIFCSIISGEIPSSKVYEDEQVLAFLDISQTTAGHTLLIPK
                     KHVRNILAMDAETASQTFERLPKIARAIQKATGATAMNIINNNEELAGQTVFHAHVHL
                     VPRYSQEDGIAIQYTTHEPDFPALAALAQQISQEISQ"
     gene            complement(44502..44945)
                     /locus_tag="TVB59_000239"
     CDS             complement(44502..44945)
                     /locus_tag="TVB59_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009185.1"
                     /translation="MNLSRFLTFGLVSLSALSISGLVQTEAKANEWQTIFEKPQEVVI
                     TDGWQTISEKPQEVSTANEWQVSSEEAQESVPDKFSQNEDPSLWAVPDKFSQNEDPSL
                     WAVPDKFSQNEDPSLWAVPDKFSQNEDPSLWAVPDKFSQNEDPSL"
     gene            45482..46207
                     /locus_tag="TVB59_000240"
     CDS             45482..46207
                     /locus_tag="TVB59_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019322154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1009186.1"
                     /translation="MLNIENVTGGYLNIPVLKDISFSVGNGELVGLIGLNGAGKSTTI
                     NEIIGFLKPYKGRISIDGLTLAEHEADYRKKIGFIPETPSLYEELTLAEHINTVAMAY
                     DIDVELAHKRAEPFLELFRLTDKLDWFPVHFSKGMKQKVMIICAFVIDPSLFILDEPF
                     LGLDPLAIADLIKALEVEKAKGKSILMSTHVLDSAEKMCDRFVILHQGQVRAQGTLAD
                     LQAVFGDASASLNDIYLALTKEG"
     gene            46211..47245
                     /locus_tag="TVB59_000241"
     CDS             46211..47245
                     /locus_tag="TVB59_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1009187.1"
                     /translation="MKALFRKRRQEFQHKHTKYLPYVFNDHFVLVLLFLLGFILFQYS
                     QLLKHFPANPLPIQLGLLIAVLFLLNLGSVATYLEKADQHFLLTKEAEVIAHIRSAER
                     LSFILWSSLQTVLLLPLFPLFQRLGVSLLAFVLLLGVLVLAKRLLLKRKVASFLSSKG
                     LDWEKAIAFEADRQQAILKFYALFTNVKGISTKVKERPYLNPILKLIKADSKKVWTNL
                     YLRAFLRSSDYLGLWLRLLLLSCLSLAFISNPYLAVGLALVFHYLSLFQLLSLYHHYD
                     YHYMSGLYPTKPQHKQRNLLSLLRQLSGLMLIVNLVLCRSWQNALVLIVAMGLLNLLY
                     LPYKLKKMID"
     gene            47308..48099
                     /locus_tag="TVB59_000242"
     CDS             47308..48099
                     /locus_tag="TVB59_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEL1009188.1"
                     /translation="MTTTEQDLVLTPLRGKSGKAYKGTYPNGESVFIKLNTTPILPAL
                     AKEQIAPQLLWAKRMGNGDMMSAQEWLNGRTLTREDMNSKQIVHILLRLHKSKQLVNQ
                     LLQLNYKIENPYDLLVDFEQNAPLQIQQNSYLQAIVKELKRSLPEFRSEVATIVHGDI
                     KHSNWVITTSGMIFLVDWDCVRLTDRMYDVAYLLSHYIPRSRWADWLSYYGYKNNDKV
                     MQKIIWYAQFSYLTQILRCFDKRDMEHVNQEIYALRKFREMFRKK"
     gene            48099..48734
                     /gene="trmB"
                     /locus_tag="TVB59_000243"
     CDS             48099..48734
                     /gene="trmB"
                     /locus_tag="TVB59_000243"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEL1009189.1"
                     /translation="MRVRKRKGAQEHLENNPHYVILEPEAAKGRWCEVFGNDHPIHIE
                     VGSGKGAFITGMALKNPEINYIGIDIQLSVLSYALDKVLASQAPNVRLLRVDGSSLTN
                     YFDAGEVDMMYLNFSDPWPKSRHEKRRLTYKSFLDTYKQILPENGEIHFKTDNRGLFE
                     YSLASFSQYGMTLKQVWLDLHASDYQGNVMTEYEARFAKKGQIIYRLEATF"
     gene            48794..48880
                     /locus_tag="TVB59_000244"
     tRNA            48794..48880
                     /locus_tag="TVB59_000244"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:48828..48830,aa:Ser,seq:gga)
     gene            complement(48927..50006)
                     /locus_tag="TVB59_000245"
     CDS             complement(48927..50006)
                     /locus_tag="TVB59_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEL1009190.1"
                     /translation="MAFYRKLDSGWEYRITYRDSQGKKREKSKRGFKTKTLAKVAAQQ
                     AETDLNTLTADLLDITVLDYNKRWADIYKRPHITAKTWQTYTKNFKHIEHYFGTRKLK
                     SITHTFYQQVLNDFGEKVAQQTLDKFHYQIKGACKMAIRDGIIRDNFADEAIVRSQKP
                     AKEESEKFMEESEYLAFIKTAKEKIKYPSYLTTYIIAITGLRFAEAQGLTWKDIDFDN
                     GYVDVNKTFDYSISQNFRPTKNEQSIRKVPIDNNSVELLKYFKDNHYQDNKLSRICFG
                     ASNNATNKVIKRVTGRNLTNHSLRHTYASYLIAQGVDLISVSKLLGHENLNITLKVYA
                     HQIESLKEKNDHQVKNIFQNLKIDG"
     gene            complement(50125..50676)
                     /locus_tag="TVB59_000246"
     CDS             complement(50125..50676)
                     /locus_tag="TVB59_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015986700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009191.1"
                     /translation="MDITKLKGFAIAAAGKAKDGAIKANELRKKASQESKMILPPALN
                     LGLGTPTAIRKTIDGKYYIGFYSETPELYEFVNLQFDGSRIIEKTVTKGKTTQRGRSG
                     SVLGGAAIGTVLAPGVGTIVGGMTGGARKKKGTINTTATTTSEEIPGKATVALRNIQT
                     GEVKTLKTKLTQAQYVNVNNFFK"
     gene            complement(50687..51070)
                     /locus_tag="TVB59_000247"
     CDS             complement(50687..51070)
                     /locus_tag="TVB59_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEL1009192.1"
                     /translation="MMTPETVCQEKGIDLVYFDGRGTNTPGMFNKKHNVIAIDTYLDG
                     IYKHKVIYHELGHREHTASYYKLNKEKAELQADRCMIHHLLKEELSYWDNMEDFNYIQ
                     FMEKYELTSIADEVMVKEELEFLIS"
     gene            complement(51084..51443)
                     /locus_tag="TVB59_000248"
     CDS             complement(51084..51443)
                     /locus_tag="TVB59_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1009193.1"
                     /translation="MTMFEVYSRIEALAKKRGVSLQKVATDIGLSENYIYNLKSKKTA
                     NTDPIEKIANYFNVSTDYLLGRTDNPKIAQDGHASVAIDLKKDAEETFFFDGHELNDE
                     DIDLITSILETRIKNRK"
     gene            52199..52390
                     /locus_tag="TVB59_000249"
     CDS             52199..52390
                     /locus_tag="TVB59_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009194.1"
                     /translation="MSDNTVAVEKIKKYLLDNKLKQVDLAVTYNKEPQDVANILAGRK
                     KDPASNRFVLKVISDLKIR"
     gene            52411..52641
                     /locus_tag="TVB59_000250"
     CDS             52411..52641
                     /locus_tag="TVB59_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009195.1"
                     /translation="MLNAILERNLMTDAEKQNYDALFINIFERLEKLEEGYDFSSVAT
                     TTGVQNSGGVQYRECQEDGTVVKTVSKRSLGY"
     gene            52707..52982
                     /locus_tag="TVB59_000251"
     CDS             52707..52982
                     /locus_tag="TVB59_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015986704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1009196.1"
                     /translation="MDSRLLQMLDEFEAGLIDRKVKVMKMINNETETYPLELNKKQVS
                     KMFGIDPKTFDARFNSHKDFPRIETGGREKYPRDLVIEWYHRNWSIT"
     gene            52979..53149
                     /locus_tag="TVB59_000252"
     CDS             52979..53149
                     /locus_tag="TVB59_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015986705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009197.1"
                     /translation="MNKLELFLLATTIVLAIIARVQYEIIKKHNSPENKRKIFREVAL
                     ENSKKWSAERYV"
     gene            53142..53345
                     /locus_tag="TVB59_000253"
     CDS             53142..53345
                     /locus_tag="TVB59_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000049475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009198.1"
                     /translation="MSKWELQKQLLENATDFESTVEALLDLNESGEISDLELLLNLKD
                     KFRSYSKEKIRILNEILKLGGAE"
     gene            53342..53728
                     /locus_tag="TVB59_000254"
     CDS             53342..53728
                     /locus_tag="TVB59_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009199.1"
                     /translation="MMTTFEKIIKKINRIEGELVKPEAERRDSLPILSAQLGSIKQDL
                     KLMLWIELPSLNNVEKYEALYQGNDFKFSETFLERQATRKAFWRRLAKETFKEDQDRR
                     NFVKLAEKEFKGATLSWQEFLWGKKK"
     gene            53725..53877
                     /locus_tag="TVB59_000255"
     CDS             53725..53877
                     /locus_tag="TVB59_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009200.1"
                     /translation="MNISIKLIGETLAGLNDILRQGGLSCSQNQALADAVFILTALKQ
                     VIEERK"
     gene            53874..54077
                     /locus_tag="TVB59_000256"
     CDS             53874..54077
                     /locus_tag="TVB59_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009201.1"
                     /translation="MNYLEYALVYLERELEIIDNEVIEVELPGGDWEFVPNPYYEKGL
                     HDSPHYRSQVAKDILDIKGLLGR"
     gene            54165..54464
                     /locus_tag="TVB59_000257"
     CDS             54165..54464
                     /locus_tag="TVB59_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009202.1"
                     /translation="MIEVTFKAESMAGVFDAMREALDMPKTVTKDVVEEKPAPKKKEE
                     SVTLTLADIKKMAKAKVEEGKSKDIKEVLKEMNVAKVGELEEYQFAEFVEKLEAL"
     gene            54464..55621
                     /locus_tag="TVB59_000258"
     CDS             54464..55621
                     /locus_tag="TVB59_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015986706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2800 domain-containing protein"
                     /protein_id="HEL1009203.1"
                     /translation="MPVENHALLSASSAHRWLYCPMLPRLEADYPSRDTVYTQEGTSA
                     HELSEIKLMYKSGKITKRKFNTLTKTFKENSDFYNEEMEEMTELYTDIVMEHLNAYEN
                     AEIELEKRVDFSDWVPGGFGTSDVVILADGVIEIIDLKYGKGMPVSANQNPQMGLYAL
                     GAYASYDMVYDFDRIKMTIIQPRLDSVSSVDIYVEELLYWADNVVLPMAAQADAGIGD
                     WNLSEKVLQWSPVAAKLVPRAQENWELIDKYDYQEPVYLSDEAVAEILDKASAIKKWV
                     ESVEAYALKEALSGKEVPGYKIVEGRSNRVITDKDKAIDILQDNGFDDEIFKPKELLA
                     MGALEKLIGKTTFADLLAEVIDKPQGKPVLVPEKDKRPAINSLEQAIKDFE"
     gene            55635..56198
                     /locus_tag="TVB59_000259"
     CDS             55635..56198
                     /locus_tag="TVB59_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2815 family protein"
                     /protein_id="HEL1009204.1"
                     /translation="MTTTPNTTKVVTGKVRLSYVALLEPKAFEGQEAKYSTVILIPKT
                     DKVTIKKIKDAQKAAYEAAKDNKLKGVKWERVKTTLRDGDEEMDTEEHPEYAGHVFMS
                     VSSKTKPQIIDKYKNPVDSADEVYSGVYARVSLNAYAYNTAGNKGISCGLNNVQIVAK
                     GDYLGGRSSADADFDEWNEEEDEDDIL"
     gene            56241..58163
                     /locus_tag="TVB59_000260"
     CDS             56241..58163
                     /locus_tag="TVB59_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase"
                     /protein_id="HEL1009205.1"
                     /translation="MRHLNIDIETYSSNDIKNGVYKYADAEDFEILLFAYSIDGGEVE
                     CLDLTRQSLPEDIKDMLFDDKVRKHAFNAQFERVCLSRYLGLPYYLDPCQWQCTMVLA
                     QELGLPSSLEKCALYLKLAQEKDTSGKNLIRYFSLPCKPSKTNGGRTRNLPEHAPEKW
                     QMFIDYCIQDVVVEMAIAEKLESVPVHDREWDYYACDQRINDRGVALDKELVASALYC
                     KDVKMESLSGELKAITGLANPNSRAQLLPWLKEHGYSANGLTKADVEQELKTAEGELK
                     RVLELKLQTAMSSLKKYEAMERAMCSDGRVHGLLQFYGASRTGRWAGRVVQVQNLARN
                     YIKDLDDAREYVKKRDIDAVEILYDSLNDTLKQLVRTALVAKDGCTFYVSDFSAIEAR
                     VIAWFAGEQWRLDVFSTHGKIYEASASQMFGIPIEEIDKELRQKGKISELALGYQGGP
                     GALKQMGALNMGVKEEELQGLVDDWRRANKKIVQFWKDVQRAAIKAIKSRAPIKLGKL
                     RFRYRKGFLFITLPSGRNLAYARAKVEPGDYGDKIIYEGQGDKAYFTAQETYGGKLVE
                     NIVQATARDILAEALLRIEAAGYGVVFHVHDEAIIEGSGLTIEEVNDLMAQAPEWAEG
                     LPLNSEGYVTKYYMKD"
     gene            58168..60552
                     /locus_tag="TVB59_000261"
     CDS             58168..60552
                     /locus_tag="TVB59_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEL1009206.1"
                     /translation="MKQEKLIVKSSPLQELHIATGSSRTAKTWKNITLTWQELVERLE
                     KPTVTQETFAEYQKMSRAEKGQAKDVGGFVGGWLKQGKRKNENVQSRSLVALDADSPS
                     KDFLDRLDLLADYAYVLYSTHSHSKKAAKYRLIIPTDRLMMPDEYEPVARYLANQLGM
                     SNFDDTTYQSVRLMFWPSHSRDADFTFKYNDEAFLSVDEVLDTYPDWHDSSFWPESPT
                     HAVKRQREAKKQGDPLSKKGLIGAFCRNYDIRQAIATFLPEVYEEGTTPDRYTYTDGS
                     TANGLVIYDDVFAYSHHGTDPVGDTLVNAYDLVRIHKFGEQDSEAKDNTPTNKLPSSK
                     AMNAFVCDLPEIKDYLMAEALGDFDEELPVEDDRSWLEIDERGEPEVNSYLLATQIIK
                     EVPIYWDGLEFLRYDAKKGIWLPNAEEYLKSYISTKKLGKITKIRHISETIVAIKAQA
                     FSSEVFTESDLNKIVLVNGVYDLRDNSFKTKFDPELHARSSHPVAYAPEAACETFEGF
                     LRETVGAENIDFIFEWFGYNFYREYTIQKMLFIYGSGGTGKSTLINILREMIGADNYS
                     AVTLQYLMQERFAKIGLYRKTANFDTDAKPQYLADGATLKMLTGEDTIHADRKNKEPI
                     NFYNYAKLSFAMNELPPMRDFSGGLKRRMMILEMDKVLTQEVKAKYPLDKIMSEVPGI
                     FNRAMEGLRNALSKRDFSISASMRSSVEKWEKGNDVVAMFLEDECELGEDFKVPVRDV
                     YPAYKFYCQDSGYKPLARNSFTQRMNELNFENKNAKMGGKTVRCWIGFRIKGEF"
BASE COUNT        17318 a        11661 c        14292 g        17481 t
ORIGIN      
        1 tcctgctcca acttgtcata aatgtagcta tcaaaggttg caacgctttg cagcgcacgt
       61 gtatcaacaa catgggtcaa aatcaaggca gcaccattac gcaaagcgac attaaccccc
      121 ttgtgaaagg ctaattcgga gccatgagag ccatcaatag cgaccatgat acgttcatat
      181 gtttgtgaca tcggtttatc ctcctttgaa ctttatctct atagctatta tacctttttt
      241 gaggagaaat tgaaaacgtt ttaatgattt tctgagctat tgttcaccaa atagcccagc
      301 tattccctga ggtgaggata ccttgagcta gaagctagct tagatagcct tattaatagc
      361 tgctgcttag cttgcttaga gctttggttg agcttttggc attctttaag ctcatagaaa
      421 agtgctttct attttaattg ttttggttta taatatgggt tacgaggtaa tgagactatg
      481 aaaataattg aaaaatcatc aaaattagaa cacgtagcct acgatattcg aggtccagtc
      541 ctggacgagg ctaatcgtat gatagctaat ggtgaaaaga tccttcgatt aaatacaggt
      601 aacccagcag cctttggctt tgaggctcca gatgaggtta ttcgtgattt gattctcaat
      661 gctcgctcca gcgagggcta ttctgatagc aaggggattt tttcagctcg taaggccatc
      721 atgcaatatt gtcagctaaa gggctttcct gatgttgaca ttgatgatat ttatttggga
      781 aatggtgtct cagagctgat ttcgatgtct cttcaagcct tgctcgataa tggtgatgag
      841 gtgctggtgc caatgcctga ctatcccctt tggacagcct gtgtcagcct aggtggtggg
      901 catgcggtgc attacctgtg tgatgaagag gctgaatggt atcctgatat tgctgacata
      961 aaagccaaga tcactgagcg cacaaaagct atcgtcatta tcaatcccaa taacccaaca
     1021 ggtgctctct accctcgaga ggtcttagag gagattgttg caattgccag agagcatcag
     1081 cttatcattt ttgcagatga gatttatgat cgtttggtca tggacggtgg ggagcatatc
     1141 gcaattgcca gccttgcacc tgatgttttt tgcgtgtcaa tgaatgggct gtcaaaatca
     1201 caccgtattg ccggctttcg agtgggctgg atggtcttgt caggccctaa aagacatgtc
     1261 agaggttaca ttgaaggctt gaacatgctg gcaaacatgc gcttgtgctc caatgtctta
     1321 gcgcagcagg tggtgcagac ctccttagga ggacgtcagt ctgttgatga gctcttgctt
     1381 ccgggtggtc gcatctttga gcaacgtaac ttcatttacc aggccattaa tgccattcca
     1441 ggcctatcag ctgtaaagcc taaggcaggc ctctatttgt ttccgaaaat tgatcgaaat
     1501 atgtaccgca ttgatgacga cgaggaattt gtcctacagc ttttgaagca agaaaaggtc
     1561 atgctggtac atgggcgtgg cttcaactgg aaggagcctg atcattttcg cgtggtctat
     1621 ctgccaacag tagaagagct agctgacgtg caagaaaaga tcacgcatgt tctcaagcaa
     1681 tacaagcgct aatatgattc tcatacaaaa attggatcgc gagatccttt ttgtttttca
     1741 gcaaaataag gctctggcct catccgaatt gtaggtataa tagccaattt tctgataatt
     1801 ccttgcaaaa gctagggtcc tttgatataa ttgtaacgca aataattaaa aggaaaagaa
     1861 aaaatgccaa atttattaga aaaaacccgt aagattactt ctattttgca acgttctgta
     1921 gacagcttgg aaacagaact cccctataac actatggctt cacgcttagc agatattatt
     1981 gattgtaatg cttgtatcat caatggtggc ggcagcttac ttggctatgc gatgaagtac
     2041 aagaccaaca cagaccgcgt cgaggaattt tttgaaacaa gacagttccc agatgcttat
     2101 gtcaaggcag ctagtcgtgt ttatgacact gaagcaaacc tttctgtgga aaatgaacta
     2161 acgatttttc ctattgagtc aaaggatatc tatcctgatg gtttaaccac gattgcccct
     2221 atctatggtg gcggcatgcg cttaggtacc ttgatcatct ggcgtaacga caatgaattc
     2281 agtgatgatg accttgtttt agttgaaatc tcaagcactg tggtcggtat tcagctgtta
     2341 aatcttcaaa cagaaaacct agaagaaacc attcgtaagc agacagttgt taatatggca
     2401 atcaacactc tatcttactc tgaaatgaag gctgttgcag ctatccttag tgagctagat
     2461 ggcaatgaag gacgcctgac cgcttcagtg attgcagatc gtattggaat cacacgatct
     2521 gtcatcgtga atgcccttag aaagctagag agtgcaggta tcattgagag tcgctctcta
     2581 ggaatgaaag gcacttatct caaggtgatt aacgaaggca tctttgacaa gctaaaggaa
     2641 ttttaatagc tcagatgcga tcgtctgcta agcccaaggc ttgcctttag ctttgctagc
     2701 tgtgattagt cagagcaggt agtgaaagtg ttagctatga tcaaagtctt gctgcttata
     2761 gagcagccat tcattagcca gagccctgct tggtaagggc tagacttggt ctttatgacg
     2821 gcttatcgga gtttcttagc agctgtggag gacttcacac attattatag cgtcccctca
     2881 aaggttctag cattggctgg cttttgaggg gtattttttg tattttcgct gtgattcagc
     2941 atgagatgaa catgacagat gcatgaaaga tttttagcaa gaaaataagg ctttctgtat
     3001 ttcaatgttc agctatttca ggaatatatc ttattttcat atagaaaaac gttgaaagtg
     3061 tctacttaaa tctatactat agttcagaaa taactgtttt tcgcctttat cgtgtataaa
     3121 tcaatccgct gtcttgacag ctgtcgtgtt tagtggtaaa ctataagtgt ctaatcatac
     3181 tgaatattaa aagcaggctt agttcttatg gcttgctgtc atgcagctaa gagagcataa
     3241 gctttttggg gagggataag ctgtgaaggc cttgatttct attgattaca cgaatgactt
     3301 tgtagctgat gatggtagcc tgacggcagg agcacctgct caggtgattt cagaggcgat
     3361 ggctagcgtt gttgaggctg cctttgaggc cggctactat atcttttttg cgattgatgc
     3421 ccacgaggag ggagatagct ttcatccgga ggcagccttg tttccgccgc ataatattat
     3481 cgggacaagg ggtcgggacc tgtatggtcc tttgatgacc gtatatacca gataccagca
     3541 agatcagcgg gtcttttggc tggataagcg gcattattct gccttttcgg ggactgattt
     3601 ggatattcgt cttcgtgagc gtggcgtcac gacgctggtc ttgacaggtg tgctgacgga
     3661 tatttgtgtc cttcatacag cgattgatgc ctataaattg ggctacaagc ttgagattat
     3721 cacatcagca gtggcgagca attcaacaga aaatcaccag tgggcgctga accactgtag
     3781 gactgtccta ggagcaaagc ttcttgatcg gctttcttag gcgatcgttc gatcagctgg
     3841 gataggctaa tcaagtaagg cagtattagc tgctgcttgg ctcagcgctg atcttaaggg
     3901 cttcttagtg agatcttttg gtcttggcta ggaggctttt tgttattaag tttttcgcta
     3961 atcccagcta cgcatacacg tgaataaaat gcaggtagct atgctctagc cacattgccc
     4021 ttttaacctc atcaattgct caaatgcagt ttagttatag cctggctgtt cttgaaaaaa
     4081 gcaggttgag cttatgaaaa acgttatcag aaaacgtcag ttgccacatg catttgacgt
     4141 gaaatcccag cagtccgcta tggtaaataa agctaattat gatataatgg ttaagactat
     4201 gtaaaattgg gttattcagg ctattatcaa gcgtttgaaa cagcaaggcc ttgtggctga
     4261 tgatggtctg ctttaccttg gataggagaa ttcatgaaaa tttctgaaga agaggttcgc
     4321 cacgttgcgg ccctatcaaa gctatccttt tcagaaagtg aaacaactga gtttgcgaca
     4381 acattatcaa aaatcgttga catggttgaa ttgctaaatg aagtggatac gacaggtgtt
     4441 gccattacca ccacaatggc agacaagaaa aatatcatgc gagctgatat cgctgaggct
     4501 ggagtggatc gcaagctcct gtttcaaaat gttcctgaaa aagaaaatca tttcatcaag
     4561 gtaccagcta ttcttgatga cggaggagat gcctaatgtc ttttaatcat catactatag
     4621 aagaattaca tgagcttctt gttgcaaagg acatttctgc agttgagcta acaaaggcaa
     4681 cccttgagga tatcaaggcg cgtgaggagg ctgtgggttc tttcattacc attgcttgcg
     4741 aggctgcttt aaagcaggct gctgcacttg atgctaaggg gattgatcct gacaatgtga
     4801 tgtcaggaat accactagct gtcaaggaca atatctcaac caaggggatt ctgacaactg
     4861 ctgcttctaa gatgctttat aattatgagc cgatttttga tgcgacagcg gtagctaatg
     4921 cctacgacaa ggatatgatt gttattggta agaccaatat ggacgagttt gctatgggtg
     4981 gctcaacaga aacgtcttat ttcaagaaaa ccaaaaacgc ttgggatcat agcagggttc
     5041 ctggtggttc atcaggtggc tctgcaacag cagtagcttc aggtcaggtt cgcttatctc
     5101 ttggctcaga cactggcggc tctattcgtc agccagcagc ctttaatggt gttgttgggc
     5161 ttaagccgac ctatggggct gtttctcgct atggcttgat tgcctttggc agctcgctag
     5221 atcagatagg gccttttgcg ccaacggtaa gagaaaatgc ccagctgcta tcggtcattg
     5281 cagggagtga ccgcaaggac tcaacctcag cacctgtaca gatcgctgac tacacaatta
     5341 agatcggtca agacatcaag ggcatgaaga ttgcactacc taaggaatac cttggcgaag
     5401 gcattgatcc taagattaag gagacggttt tggctgctgc taagcatttt gagaagctag
     5461 gagctatcat tgaggaggtc agtctgccac atagcaagta tggggtggct gtctattata
     5521 tcatcgcttc atctgaggcc tcatcaaacc tacagcgctt tgatggtatt cgctatggct
     5581 ttcgtgctgc tgatgccaag agccttgagg acatctatgt caagacgcgt agtcagggct
     5641 ttggtgatga ggttaagcgt cgtatcatgc ttggtacctt tagcttatca tcaggctatt
     5701 acgatgctta tttcaaaaag gcaggtcagg ttcggacgct gatcattcaa gactttgaga
     5761 aggtttttgc tgattatgac ttgattttag gaccaacagc accaacagca gcctttgagc
     5821 ttgatacgtt gaatcatgat cctgttgcca tgtatttggc tgatcttttg accattccgg
     5881 tgaatctagc gggcttgcct gcaatctcta ttccagcagg ctttgcagat ggcttgcctg
     5941 ttgggcttca attgatcggt ccaaaatata gcgaagaggt catctatcag gtagcggtag
     6001 cctttgaagc gactactgac taccacaagc agcagcctat gatttttgga ggtgacaggt
     6061 aatgaatttt gaaaccatta ttggacttga ggtccatgtg gagttgaata ccaattctaa
     6121 gattttctca ccttcatcag ctcattttgg agaggatcca aatgccagca ctaatgtgat
     6181 tgactggtct ttcccaggtg tccttccagt gatgaacaag ggagtcattg atgcgggaat
     6241 caaagcagca cttgctctta acatgtctat tcatcagcac atgcactttg accgtaagaa
     6301 ttatttctac ccagacaatc ccaaggccta tcagatttca cagtttgatg agccgattgg
     6361 ctacaatggc tggattgata ttactcttga ggacggctca accaagaaaa tccgtattga
     6421 gcgtgctcac ctagaagagg atgccggcaa aaatacgcat ggtacagatg gttattccta
     6481 tgttgacctc aatcgtcagg gagtgccctt gattgagatc gtctcagagg ctgacatgcg
     6541 ctctccagag gaggcctatg cttacctgac tgccctaaag gaaatcattc agtatactgg
     6601 tatttctgat gtcaagatgg aagaggggtc catgcgtgtg gacgccaata tctccttgcg
     6661 accatacgga caagaggcct ttggtacaaa aacagaattg aaaaacctga actcatttag
     6721 caatgtgcgt aaggggcttg agtttgaggt ggagcgtcaa gccaaaatcc tacgctctgg
     6781 cggtgttatt cgtcaggaga cacgtcgtta tgacgaggca agtaagggaa cgattctcat
     6841 gcgtgtcaag gagggagcag cagactaccg ctatttccca gagccagatt tgccattgtt
     6901 tgagattgat gacgcatgga ttgaggatat gcgtgcagag cttccaagat ttccggcaga
     6961 caggcgagct agctacatta atgctcttgg cttgtcagcc tatgatgcag gtcagctgac
     7021 agcaacaaag gctttgtctg atttctttga gcaggctgtg gcacttggtg gtgatcctaa
     7081 gcaggtgtct aattggcttc agggtgagat ggctcaattc ttaaatgctg agggcaagac
     7141 gattgatcag attgccttga ccccagaaaa tctcgtggaa atgattgcga tcatcactga
     7201 tggcacgatt tcatcaaaaa tcgccaagaa ggtttttgtt catttggcaa agcatggcgg
     7261 ctcagcgcgt gcttatgtgg aaaaggccgg cttggttcaa atttcagacc cagctgtctt
     7321 gattccaatc attcatcagg tgtttgctga caatgaggct gctgtggcag atttcaaatc
     7381 aggcaagcgc aatgctgaca aggcctttac tggttttctg atgaaggcca caaaggggca
     7441 agccaaccca cagatagctc agcaattgtt agcccaagaa ttgcaaaaat tgctggatta
     7501 aggagtcgtt atgactggca ttgagtctga aacagagttt tcaggctctt tatgatggta
     7561 ggctctttag gacaattctg tgataatacc tcgctatccg aagctgtaag aggtagctta
     7621 tcggtctgtt gttaatgact gttaagcagg cttggtgaag tctaggctag agctatcaag
     7681 gtattatgag tggccttatc atggcatgga ttaaaaagag gaagataata tgtcaagaaa
     7741 tggaaaaggc agtaccatga ttttactagc cggaatcgcc tggggtctct caggggtgtc
     7801 agggcaatat ttaattgctc atggggtcgg catcaatgcc ttgacctcac taaggctcat
     7861 tatttcaggg cttgtgctgt cagctatggc ttatgtgcgg caaagagagg ctgtcatcag
     7921 cttactcaag gacaaaaggc ttttaagaga gctgttgatt tacagtctat ttggtctcac
     7981 acttaatcaa tatgcctatc tgcttgctat tcgttactct aatgctggta cagccacagt
     8041 cctgcaatac ctttccccca ttttggtgct ggtctaccta tcgttcaaat caagacgcct
     8101 gccggctgtg ggagagagct gtgctatttg cctagcgatc ctaggaacgg ttatcatggc
     8161 ctgtcatggt gatctttccc atctggcaat caatcctatt ggacttttct gggggctttt
     8221 tgcagcggtg acctatgctt actgtgtcat caagcctgct aagctgattg ccgactgggg
     8281 gagcttgctg attgttggtc ttgccatgct gatgggagga gtgatttttc cgatcctgac
     8341 aagagcatgg cagtacccat tggcaatgac ttatgggaat ctacgggccc tgtttggcat
     8401 tatcggtatt gggacaattt ttgcctacac cttttttcta aagggggctt caatcattgg
     8461 accgatcaag gctaccttgc tggcttcaat tgagccggtt gcctctgtct gctttgcgat
     8521 tatcctgatg aaagagattt ttcaccctat tgatctgtta ggaatggcct tgattttaat
     8581 agcagtgctt gtgatatcgc tgagagactt attgcttact aagagaaaaa agcagcttgc
     8641 tcttaatatc aagcgaccac catcatctga ctgatataag gcaagggtat ggtataataa
     8701 gacaaaacat aaaggagatt tgcgatggtt tggtcattaa ttgttggagc tattatcggc
     8761 atggttgcag gtaggataac agaaaaaagc cattcgatgg gctgtttcac aatgactgct
     8821 gctggtttga taggctctgc agttggtcaa aagctgtttg gcgactgggg tattcagctg
     8881 gcaggcatgg ctgttttccc ttcaattcta ggagcagcta ttgtgataat tgttgcttca
     8941 gcgctctttg gcaaaaaaca ataagccagg agtacttgtg acgttcaaat atataaaaat
     9001 ccttgtatca gtatgatacg aggatttttt ggttatcaga tttgtaaaaa caatcgaata
     9061 tatcagatga taaaaattta aaagaaatat gataaagtct tgactatata tactatttct
     9121 tggtattttt accaaaaaat atggagagag ttaaaaaagt atgagaaaaa cagaaggacg
     9181 ttttcgcaca tggaagtcca aaaaacaatg gctatttgcc ggtgcagtgg tgaccagctt
     9241 gctgctggga gctgcacttg tctttggagg tttattagga agtcttggtg gctcatccca
     9301 tcaagcgagg ccaaaggagc agccagtcag ctcgattgga gatgacgata agtcgcacaa
     9361 gagctcatca gattcaatgg tcagtcggcc accgaaaaag gataacttgc agcctaagcc
     9421 ttcagatcag cctactaatc atcagcatca ggctactagc ccgtcccagc cgacagcaaa
     9481 gagctcaggt catcatggga atcaacctca gtctctcagt gtgaacagcc aaggaaatag
     9541 tagtggacag gcctcagagc ctcaggctat tcctaatcaa gggccttccc agccactggg
     9601 gctgagagga ggtaacagct ctggttcagg tcatcaccat cagccacaag gaaagccaca
     9661 gcacttagat ctaggtaagg ataattctag cccgcagcct caaccaaagc ctcagggcaa
     9721 tagtcccaag ctgccagaaa aaggcttgaa tggtgaaaat cagaaggaac cggagcaagg
     9781 tgaacgaggt gaggctggtc ccccactttc agggttgagt ggtaataatc aaggccgtcc
     9841 ttcgcttcca ggcttgaatg gtgagaatca gaaggaacca gagcaaggtg aacgaggtga
     9901 agccggtccc ccatcaactc cgaatttaga aggaaataat cgtaaaaatc ctttaaaagg
     9961 attagatgga gagaataagc caaaggaaga tttagacggt aaaggcttaa gcggagaaaa
    10021 tgatgaatca ccaaaactta aagacgaaca cccctacaat catggtcgtc gtgatggtta
    10081 ccgagttggc tatgaggatg gatatggtgg caaaaagcac aaaggagatt atcctaagcg
    10141 gtttgatgag tctagtccaa aggaatataa tgactatagt caagggtata atgataatta
    10201 tggaaatggc tatttagatg gtctagctga tagaggtggt aagagaggat acggctattc
    10261 ttacaatccc gactaatctt ctgctatccc ttaattaacc tacaaaaaag ctgggcttcc
    10321 ttagacccag cttttttggc agcttcaaac gtcttatctt ttattagctg ctattatatt
    10381 ataaagtcta aatattaata aacggtatca attggataac aaactctttt ttctggtacc
    10441 cattgttcta tttttgcaag gggctaccag acctcttgtc tctgatagct ttctcttttt
    10501 gtttgtgata aaatataaca catattgagg aggtgtgcca tgaaagctat cattacagtt
    10561 gttggtaagg acaatcaagg gattgtcgca ggtgtttcag gacaaattgc tgcattaggg
    10621 ttaaatattg atgacatttc acagaccgtt ttagatgatt attttaccat gatggccatt
    10681 gtctcaagca gtgaaaagca ggattttgct catctgcgtg aggtgcttca ggcttatgga
    10741 aagcaattgc aggtgacgat taatattcaa agcgcagcga tttttgatgc tatgcataac
    10801 atataaggag cttgatgact atggatatta gacaggttcg tgaaacagtt gagatgattg
    10861 aggagcagca ttttgatatt cgtaccatta cgatgggaat ttccttgctg gattgtattg
    10921 attcggatat tgatagagct gccgctaaga tttaccaaaa gattacgaca aaggcagcta
    10981 atcttgtggc ggttggtgat gacattgcag cagaactagg tattcccatt gttaataagc
    11041 gcgtctctgt aactccgata gcccttattg gggcggcaac agacgcagaa gactacctgt
    11101 cgcttgcaaa agctctggat caggctgcct gtgatatcgg agttgacttt atcggtggct
    11161 tttcagctct tgtgcaaaaa ggctatcaaa agggtgataa gattttgatt gagtctattc
    11221 ctcaggcttt ggctcaaaca cagaaggtct gcgcttcggt caatgttgga tcaacaaggt
    11281 ctggtattaa tatgacagca gttgcagaca tggggcgtat catcaaggaa accgccaaag
    11341 cctctgagat aggggcagca aagctagtag tctttgctaa tgctgttgag gacaatcctt
    11401 ttatggcagg agcctttcat ggtgtcggtg aggcggatac ggtgattaac gttggtgttt
    11461 caggacctgg tgtggtcaaa agagccttgg aaaaggttcg tggtgaaagc tttgacgttc
    11521 tagccgagac cgtcaaaaaa acggccttta aaatcacgcg tatcggtcag ctagtgggac
    11581 agatggcaag tgagcggcta ggtgtgggct ttggtgttgt ggatctgtcg ctagctccca
    11641 ctccagcagt tggtgactct gtggcacgtg tcttagagga gatgggactt gaaatagttg
    11701 gcacacatgg cacgacagct gccctagctt tacttaatga cgcagtcaaa aagggtggtg
    11761 tcatggcttg caaccgagtg ggtgggttgt caggtgcctt tatccctgta tcagaggacg
    11821 agggcatgat tgcagcagtg cagggaggct cgcttaatct tgaaaagcta gaagccatga
    11881 ctgccatttg ctcggttggt ttggatatga ttgcgatccc agaggagaca ccgtctgaaa
    11941 ccattgcagc catgattgct gatgaggcag ctatcggggt gattaatcaa aagacaacag
    12001 ctgttcgtat tattccaaag ggtaaggagg gtgatatgat tgcttttggt ggtcttttag
    12061 ggacagctcc ggttatggct gttaatccgc attcatcggc tgactttatt gctcgtggtg
    12121 ggcagatacc agctcctatc catagcttta agaattaacg gctagcactt gcatggtttt
    12181 gcaagtgttt tcttttaatg ctataatagc agagagactt tggaggttca ttatgacaaa
    12241 aacaagatta tacattgtca gacatggcaa gacgatgttc aacaccattg gtcgtgcaca
    12301 gggttggagt gataccccct tgacaaaggc aggagaagaa gggattcgtg aattgggact
    12361 tggtttgaag gctgctggta ttccattcaa ggctgctttt tcgagtgatt caggtcgtac
    12421 catgcagaca atggagatta ttctacgaaa gtctgaaaat gagtttttac cctacactag
    12481 agataagcgg attcgtgagt ggtgctttgg tagtctagat ggggcttatg attccgagct
    12541 gtttttaggt gttttaccta gaacaaaggc ctttgaaaat cgtgacaatc tgcgtgatgt
    12601 gccttattca gaattagcag agagtattgt cgaggttgat actgctaact gggcagagcc
    12661 ctgggaggta ttgagcaagc gtatctatga gggctttgag gctatcgcgc ttgctgttga
    12721 aaatgcagga ggtggcaatg ctatcgtggt tagtcatggc atgaccattg gaacctttat
    12781 gtggctaatt gacccagata gggaaaagca atacattgac aatggaagcg tcactgttgt
    12841 ggaatatgag aatgggcagt ttaccatcaa aacgattgga gatatgagct accgctatcg
    12901 tggtcgtgag ataattgagt caataagaga tgaagaataa cactataaga gtccttttac
    12961 aggccttggt cgtcctgttg tttttatcag gggtttacct ctttatcaag cctgaaaaac
    13021 aggctgtagg ccccaaggct aatcaaacag tacctgcccc aaaggcagct aagcaggcta
    13081 aaaagactac tgatctgcca aaggtatcaa ctacggactg gcagctggtc cttgtcaatc
    13141 gcgatcaccc tcaagaggaa atgagtcctg agttggttga gattaatggg attcctattg
    13201 ataagcgcat tgagcaggag acggctgatt ttctagcagc ggcgcagacg attgaacctc
    13261 aggagcactt gattgctggt tatcgttcgg ttgtccagca agaagagctt tatcagtctt
    13321 atattgccca agagctggca aatgatccta gcctgaccca agaggcagct gaagccttgg
    13381 ttcggaaata tgcccagcca gcaggcacta gtgaacatca gactggtcta gccattgata
    13441 tgagcacagt agataactta aacgctagtg atcctaaggt ggcacaggag attcaaaaaa
    13501 tagctccaca atttggtttt attttgcgct atccaaaagg gaagcagact agcacaggga
    13561 ttgagtatga ggactggcat tatcgctatg ttggtaaagc ctctgcccta tacattaccg
    13621 ctcatagcct cagcctagaa gaatacctaa cacgattgaa ggagaaaaaa tgagaaaacg
    13681 acttaaattt tcctattttc tagtgttttt agtgttcatt atggtggctt tgattggtcc
    13741 cttgctgttc aatgccaaag gcacatcggc cagtcaggag atgtctgttc cctatacaga
    13801 gaggcaattt atccagttgg ttgctaagga ggtcaagcca ttggccaaaa actatggcat
    13861 tcgtccttct attttgattg gtcagattat tttagaaacc aattatggca gaaccctgtt
    13921 ggcggccaaa taccacaacc ttttttcact gcagccagct ccagggcagg cttccattag
    13981 cctcaagaag caagcagcct caaagcacaa gacagcctat gctatctatc gggacagaga
    14041 ggactctatc agagcttact tatcatggct tagtcaaggc acaggcgagg agaaaaagct
    14101 ttaccaaagc ctagcaaccg aaaaagggta taaaaaacct gctaaaagtc tgcagaccta
    14161 tcgctattct gatgataagg gctatgccca aaggcttgtg cagctgattg aagcaagagg
    14221 tttgacaagc tatgatgatt gaggagatga aaaagacacc gaaacaaccg gtaagctcag
    14281 gtatttgctt tagtaggtat tgcaactttc tatcagcttg aaggtgtaag ccttaagagt
    14341 aggagctgtg agcacgcagc ctgatttatc ctgctctact aaaggcttga ttgttaggcc
    14401 ttaaggcttc aggcagttaa gctaatcccc cttacagctt agcgctcctt ttagctagcg
    14461 agtcgggaga agccaatacc agtctgagag gtagtaagtg gctctctatt acttctttca
    14521 agcataatgt caaaggcaac actgtcaatg ttttataaaa attagcactc taaaaaaaga
    14581 gtgctaattt tttgagtttt tttcttgaca tgctagttta aaaggatata atagaattat
    14641 aaattagcag tccgatgtat agagtgctaa cagaaaggga gtgattggtt tgtgatcaca
    14701 gagagacaat ctaatatttt gaatcttatt gtagatttat ttacacagac ccatgaacca
    14761 gttggctcta aggctttgca gtcacttatt gcttctagta gtgccactat tagaaatgac
    14821 atggcaaagc ttgaaaaact aggattgctg gagaaggctc acacatcaag tgggcgcatg
    14881 ccaagtgcgg caggctttaa atattttgta gagcattctc ttaatcttgg cagcattgat
    14941 gagcaggacc tttatcagct ggtcaaggcc tttgattttg aggcctttaa gctggaggac
    15001 gttttgctaa gagccagcca gatgctatcg gatacgaccg gctatacggc ggcgatttta
    15061 gatgttgagc ctgcaaggca aaggctgaca ggctttgata ttgttcagct atctagtcat
    15121 gatgccttgg cagttttgag cttagatgag tccaagccgt tgaccgtaca gtttgccatt
    15181 cctaagaatt ttatgaatcg tgatttgctg gtgcttaagg gcattgttgc tgatcgctta
    15241 cttggcaaag atgttatgac tgttcattac aagctgcgaa ccgaaatccc tcagattgtt
    15301 cagaagtatt ttacggtgac agacaatgtt ttggatttgt ttgattatat ctttgtcggg
    15361 ctttttcgag aaacgatttt tgtctctggc aaggttgctg cccttgacta tgctggtctt
    15421 gcgacctatc agtttcttga tgaggagcag cgcttagccc tatctatcag acagagtcta
    15481 tcagaggaag agatggcaac ggttcaggtt gctgacagca gtgagccagc cctagcaaac
    15541 gtgaccttgc tgacctacaa gtttttaatt ccatacagag gatttggcct cttaagctta
    15601 attgggccag ttgatatgga ttatcgtcgt agtgttagct tgattaatgt gattggtcag
    15661 ctactggctg tgaagctaag agattattac cgttacttaa acagcaacca ttatgaggtt
    15721 cactaaggcc ttaatatgat ttaagaaaat gtaagaaagg ggtagacacc ttgtctaaaa
    15781 aaccaaaaga agagctcaag gatcaagagg acattcttga tgaggctgct gaggaagcag
    15841 tagagccagt tgaagaagct gatcaatcag ctgagcttat tgctgatgaa gcagccgagg
    15901 aaccatctga gctagagttg gctctccagc gagcagaaga ttttgaaaat aaatacctca
    15961 gagctcacgc agaaatgcaa aatattcagc gtcgtgcgaa tgaagaacgc caaagcttgc
    16021 agcgctatcg ttcacaggat ttagctaaaa aaatccttcc aagcttagat aacttggagc
    16081 gtgctttggc tgttgagggt ctgacagatg atgtcaaaaa aggcctagaa atggtgcaag
    16141 aaagccttgt tcaagccctt aaagaagaag gtattgaaga ggttcctgtg gaagcctttg
    16201 accacaatct gcacatggca gtccaaaccc taccagcaga tgatgaccac ccagcagata
    16261 gtatcgctca ggttttccaa aaaggctata agcttcatga gcgcttacta agaccagcga
    16321 tggtggttgt gtacaactag tcactaatga tggccattga aatggctcgt cattagacgg
    16381 caaccgctgt ggcggcttgc ctagactcct tactagctcg atagcaaaat ggtatcgatt
    16441 ttgctatctc acgtcgcaat tatcccgtga tgatagctaa tcaataaaat gaatcatgtc
    16501 cgaaatgacg gtaaactatg aaaataagaa ataagattgc tgctttttgc gctagcaaaa
    16561 gcgaacgaag tgagcattac cgatactctt cgccgtggca aaagtcataa aacactagtg
    16621 ttttatgact cggaaaattt gagactttag gctcaaattt cagctatgag attccatagg
    16681 aagctgctag cgtccgtgcc acataagagg agtatcataa atatataaaa gaggaaaaaa
    16741 tattatgtct aaaattatcg gtattgactt aggaacaaca aactcagcag tagcagttct
    16801 tgaaggaaca gaaagcaaaa tcattgccaa cccagaaggc aaccgcacaa ccccttcagt
    16861 agtgtcattt aaaaacggtg aaatcattgt cggtgacgct gccaagcgtc aagcagtgac
    16921 aaaccctgac actgttatct caatcaaatc aaagatggga acctctgaaa aggttgctgc
    16981 taatggtaaa gaatacacac cacaagaaat ctcagcaatg attcttcaat accttaaagg
    17041 ctatgcagag gactaccttg gtgaaaaggt aacaaaggct gttatcacag ttcctgccta
    17101 cttcaacgat gcacaacgtc aagctactaa ggacgcaggt aagattgctg ggcttgaggt
    17161 agaacgtatc gtcaacgaac caactgcagc agctcttgct tacggtcttg acaagacaga
    17221 taaagaagaa aagatcttag tctttgacct tggtggtggt acctttgacg tgtctatcct
    17281 tgaattgggt gatggtgtct ttgatgtgct tgcaactgct ggtgacaaca agctcggtgg
    17341 tgacgacttt gaccaaaaaa tcattgattt cttagtagca gaattcaaga aagaaaacgg
    17401 tattgaccta tcacaagata aaatggctct tcaacgcttg aaggacgctg ctgaaaaagc
    17461 taaaaaagac ctttcaggtg tcactcaaac tcaaatttca ttgccattca tcactgctgg
    17521 cgctgctggt ccgcttcact tagagatgag cctgtctcgt gcaaaatttg atgacctgac
    17581 tcgtgattta gtagagcgta cgaaggttcc tgttcgccaa gcgctgtctg atgcaggctt
    17641 gagcttgtca gaaatcgatg aggttatcct tgttggtggt tcaactcgta tcccagctgt
    17701 ggttgaagct gttaaggctg aaactggcaa agagccaaac aaatcagtga accctgatga
    17761 agttgtagcg atgggtgctg ctatccaagg tggtgtgatc actggtgatg ttaaagacgt
    17821 tgttcttctt gacgtgacac cattgtcact tggtatcgaa acaatgggtg gcgtctttac
    17881 aaagcttatt gaccgcaaca caacaattcc aacctctaaa tcacaggtct tctcaactgc
    17941 agcagacaac cagccagctg ttgatatcca cgtgcttcag ggtgaacgcc caatggcagc
    18001 agataacaaa acacttggac gcttccaatt gacagacatt cctgcagccc ctcgtggtat
    18061 cccacaaatc gaagtaacct ttgacatcga caaaaacggt attgtttctg ttaaggcaaa
    18121 agacctaggt actcaaaaag aacaacatat tgtcatcaaa tctaacgatg gtctttctga
    18181 agaagaaatt gaacgcatga tgaaagacgc tgaagccaat gctgaagccg atgcaaaacg
    18241 taaggaagag gttgacctta aaaatgaagt tgaccaggct atctttgcaa ctgaaaagac
    18301 tattaaagaa actgaaggca aaggctttga cacagagcgt gatgctgctc aaacagctct
    18361 tgatgagctt aagaaggctc aagagtcagg cgaccttgat gatatgaaag ctaagcttga
    18421 agcgcttaat gaaaaagcac aagcccttgc tgttaaaatg tacgagcaag cagccgcagc
    18481 acaacaagcc caggctggtg cagaaggtgc agcagataca ggctcaacaa acagtggcga
    18541 tgatgttgta gatggtgagt tcactgaaaa ataagctgtg aggagctaag gtcgctcagt
    18601 aaagctagaa actgaggcga tagtcccctc ccctaattgc tagaaaatag catagcaagg
    18661 ctaaataaat aaaaatcaaa taggcggggc gcctcgctcc gtctgttttt gtcaatgaag
    18721 gaaagaataa atgaataata cggaatacta tgatcgtctt ggggtctcaa aggacgcttc
    18781 ggccgatgat attaaacgag cttaccgtaa gatgtctaag aaataccacc cagacatcaa
    18841 taaagagccg ggagctgagc aaaaatataa ggacgtacag gaagcctatg aaaccctaag
    18901 cgattcacaa aagcgtgcag cctatgatca atacggggca gccggagcaa acggtggctt
    18961 tggtggtggc gcaggcggtt ttggcggctt cgatggtggt ggctttggcg gctttgagga
    19021 tattttctca agcttttttg gcggtggtgg tatgcgtaat cccaatgctc cacgtcaggg
    19081 cgatgacctt caatataggg taaacctttc ttttgaggaa gctgtttttg gtaccgaaaa
    19141 agaggtcagc tatcatcgtg aatcaacctg tagcacctgt gcaggctcag gagctaagcc
    19201 tggaacaagt cctacaacct gccgtaaatg tcatggctca ggggttatca atgttgatac
    19261 gcagacccca cttggcatga tgcgtcgtca ggtgacctgt gatgtctgtc atggcagcgg
    19321 tcaagaaatc aaagagcctt gccatacctg tcatggaact ggtcatgaaa agaaggttca
    19381 taaggtttca gtaaaaatcc cagcaggtgt tgaaaccggc caacaaatcc gcctacaggg
    19441 tcagggggaa gcaggcttta atggtggacc ttatggtgat ttgttcgtta ttttaaacgt
    19501 gcttccaagt aaacagtttg agcgcaatgg ctctactatt tactacagct tgaatatttc
    19561 atttgttcag gctgctttgg gagatacagt agatatccca acggtccatg gtgatgttgc
    19621 catgtctatt cccgctggaa cacaaactgg taaggtattt cgcttgaagg gcaagggggc
    19681 tcctaagctt cgaggcggag gccaaggaga ccagcatgta actgtaaaca ttgtaacgcc
    19741 taccaagctc aatgaggctc aaaaggaggc cttgaaggct tttgcggagg ctagtggcga
    19801 aaagccgatt gctccaaaga aaaaaggttt ctttgacaag gtcaaagacg ctctagagga
    19861 tatttaagcg ggtcttgttt acacactcta tgagcgattg atcacaattg tatagaatgg
    19921 ttgagcatag cacatgccaa agtttcagag tctaggacac ttttgtctta ggctctttta
    19981 ttagaggtat agaggctagg tctgagcttg gttttagggc tgcatgcttt aaattgcgca
    20041 gtcaatttta atgtattttt tacaatcttt ttcttgcata acgactgatt ctagtgtact
    20101 atagtctagt aattaatttg attgtcaaat tatttggtca taaaattatt tggtaatcaa
    20161 ataagctgtc agaaaagagg agtgatatga cgtttcaaaa tatcattttt gagcttgaag
    20221 aggatctggc cattttaacc ttaaatcgtc cagaggtgtc taatggcttt aacattccag
    20281 cctgtcagga gattctggag gctattaggt tggttaagga taacccctct ctgcgctttt
    20341 tagtgattaa ggcaaagggc aaggtctttt cagtcggtgg tgacttggtt gagatgcaaa
    20401 atgctgttga aagagatgat gttcagtctc tagttaggat tgctgagctg gttcaggata
    20461 tttcctttgc tatcaagcaa ttgccaaagc cggttatcct ctgtgctgat ggtgcggtgg
    20521 ctggtgcggc ctttaatatt gccttagcgg tggatttttg tattgctagc acccagacaa
    20581 aatttattca ggcctttgtt aatgtcggct tagcgccaga tgctggtggt cttttcttgt
    20641 taacacgtgc cgttggtcta aatagagcga ctcatctggt gatgaccggt gagggggtca
    20701 cagcagaaaa agggcttgag tacggatttg tctatcgagc tgctgagtca gataagcttg
    20761 ataagacctg tagtcagctg ttaaagcgtt tgaggcgtgg ctcttcaaat tcctacgccg
    20821 gcatgaaatc tttggtatgg caaagctttt ttgcaggttg ggaggattat gcccaaaaag
    20881 agcttgctat tcaagaggaa ttggccttta aggaggactt taaagagggc gtcagggctt
    20941 atggagatag gaggcggcca aattttcggg ggaaatagct cttatgtgct tgcaaaatac
    21001 tttgatgtct gatatacttt gatagtcaaa gtattttaca gctagggagg tgtttacttg
    21061 gaatataata agattaatca atatttagtt gatattttca acagaatttt ggttattgag
    21121 gaaatgagct taaaaacaag tcaatttaat gatgtttctc taaaggagat gcacacaatt
    21181 gagattattg gaaaatatca gcaggtaacg ccaagtgaca tcgcaagaga gctcatggtt
    21241 accttaggaa cggttaccac tagcttaaac aagctagagc taaagggcta tattgaaaga
    21301 acaagatcaa gcgtggatag acgggttgtt tacctgtcac tgaccaaaaa ggggcgtctt
    21361 ctggatcgtc tccatgcaag attccataaa aatatggtcg gtcatgtgat cgctgatatg
    21421 aatgaggacg aaatgcaagc cctgttacgt ggcttgggga acttacatca gtttttggag
    21481 gatttggttt aatggtcttt tcaaaaatta gtcaggtagc tcattatacg cctaagcagg
    21541 ttattagtaa tgacgatctg tcgcaaatca tggacaccag ccacgaatgg atttcgtcac
    21601 ggactgggat tgagaagcgt cacatttcca ctgtggagat gaccagtgat ttagccattc
    21661 gggtagcaga gcaattgtta gcagggtcag gatatgatgc gactgcactt gattttatca
    21721 tcgttgctac gattagccca gatgctagca tgccatcgac ggcagcaaag gttcaggctg
    21781 ctatcggtgc tactaatgca tttgcttttg atatgacagc ggcctgcagt ggctttgtct
    21841 ttgccttagc aatggcggat aagttgattg catcaggggc ttatcaaaga ggcttggtta
    21901 ttggagcaga gaccctgtct aagattattg attggcagga tagaagcaca gctgttttat
    21961 ttggagatgg tgctggtggg gttttattag aggccagcga gcagcagcat tttctagctg
    22021 aggccttaca tactgatggt gcgcaaggtc aaagcctgac atcaggtcag agcagtctgc
    22081 gctcaccatt ttctcaagga caggaggtca actcctttct tcagatggat ggtcgtgcta
    22141 tctttgactt tgcgattaga gatgtttcaa ggagcattac agcaattatt gagcaatcag
    22201 gcttggccaa ggaggagtta gactatctgc ttttacatca ggccaatcgg cgtattttag
    22261 ataagatggc taagaaaatt ggtatgccaa gagagaaatt tctggaaaat atgatgcact
    22321 atggcaatac cagtgcagct agtataccga ttttgctatc tgaatcagtc caaaatggac
    22381 agcttaaatt agacggcagc cagcatattt tactgtcggg cttcggtgga ggtttgacat
    22441 ggggcagtct aattgttaaa atctagttat atcatgtgcc tagcacattt ataaaataaa
    22501 tatttatatt aaggagacat aaaatggcag tatttgaaaa agtacaggaa attatcgttg
    22561 aggagcttgg caaggacgca gaggaagtaa ccttagaaac tacctttgat gatttagatg
    22621 ctgactcact tgatgttttc caagtgatct cagaaattga agatgccttt gacattcaaa
    22681 tcgaaacaga agaaggctta aacacagttg gtgaccttgt tgcctacgtt gaagaaaaaa
    22741 caaaataaag ctcaaacaag cgagaatact gattaaccag cctgctgatt aatgaactgc
    22801 tttagttggt caattgatat gtaataatcg aaccatcagg gtgagattag accctctttc
    22861 aggctctaac tcgctctttc ttcttattat gatagtttga ttatcaaatt attctcctga
    22921 tttctttgca tagaaggtta ttatgaaaac acgtattaca gaattactta atattgatta
    22981 tcccattttt cagggaggta tggcctgggt ggctgatggt gatctagcag gtgctgtctc
    23041 caatgctggt ggtcttggga tcattggtgg aggaaacgct cctaaagagg tggtcaaggc
    23101 aaatattgat cgtgtcaaag cgatcacaga taagcccttt ggggttaata tcatgctgct
    23161 atctcccttt gcagatgaca ttgtcgattt ggtgatcgaa gaaggtgtca aggtggtgac
    23221 cactggcgct ggaaatccag ggaaatacat ggagcgcctt catgaggcag gtattatcgt
    23281 gattccagtt gttcctagcg ttgccctggc taagcgcatg gaaaaattag gcgttgatgc
    23341 tgttattgct gaaggaatgg aggctggtgg ccatatcggt aaattgacaa cgatgacctt
    23401 ggttaggcag gtggtagatg ctgtttctat tccagttatt gcagcaggtg ggattgcaga
    23461 tggtcgaggt gcagcagcag cctttatgct gggtgctgag gctgttcagg ttggaactcg
    23521 atttgttgtg gcaaaggaat ctaatgctca ccaaagcttt aaggataaaa ttttgaaggc
    23581 taaggacatt gatactgtca tttcagctca agttgttggt catccggtac gctctatcaa
    23641 aaataagcta acatcagctt atgctaaggc tgaaaaagaa tttttagcag atcgtaaggc
    23701 tgctagtgac atcgaagaaa tgggagcagg agctctgcgc aacgctgtga ttgatggtga
    23761 tgtgatcaat ggctctgtca tggcagggca gattgcaggc ttaattagag cagaagaaag
    23821 ctgtgaagcc atcctaaagg atatctacta tggtgcagca gcagtgatta gtcaagaagc
    23881 taagcgctgg caagctcttg cagctgatga caaaaacgaa acgatataaa taaggagaag
    23941 tatgacaaaa acagcctttt tatttgctgg tcagggtgct cagacactag gcatgacaag
    24001 agatttgtat gaccaatatg ccattgctcg tgacaccttt gatcaggcta gtcagctttt
    24061 aggctatgat ttacgcaagc tcattgatac cgaccaggat cggttgaacc agacagccta
    24121 cacgcagcca gcaatcttaa ccgcttcagt ctccatttat cgtatcttaa cctcttatgg
    24181 ggttcatcct gatatggtgg cggggctttc tcttggagaa tattctgctc tagttgcggc
    24241 aggtgttctg agttttgaga ctgccctaga gctagttgca aaaaggggac gctttatgga
    24301 ggaggcagcg cctgctggct ctggtaagat ggtagctgtg atgaatacag aggctaggct
    24361 tattgaggag gcttgtcaag aggcttcttc ggttggtgtt gtgtcacctg ctaactataa
    24421 tacgccagga cagattgtta ttggtgggac agctgaggct gtcaatgcgg cacttgaaat
    24481 cttaaaagca aagggagtga agcgtttaat tccgctgaat gtctcaggac ctttccatac
    24541 agcactttta gcgcctgcta gtcaaaggtt ggcagaggag ctcagcaaga ttcaatttca
    24601 ggactttgat ctgccactgg ttggaaatac agaggctaag gtcatggaaa aggatcggat
    24661 tgcagaatta ttggcgcgtc aggtcatgga gcctgttcgt ttttatgata gtatcgaggt
    24721 tatgaaggct aacggtatca cccagtttgt tgagattggc cctggcaggg ttttaacagg
    24781 ctttattaaa aaaatcgaca aaaagctgct atgcagcagt gttgaagata tgccaagcct
    24841 acaattgtat ttgggaaaat aggagggaat gctaagctat ggaaattaaa ggaaaaaacg
    24901 tttttatcac agggtcaaca agaggcattg gactagcaat ggctcatcaa tttgcaggac
    24961 taggcgccaa catcgttctc aatggtcgct cagcgatttc tgatgagctg gtggagacct
    25021 ttaaggatta cggtgtgaag gttgtgccga tctcaggaga tgtttcagag ggggctgatg
    25081 ctaagcgaat ggttgatgag gctattgagc agcttggctc tgtggacatt ttgattaaca
    25141 atgctggcat cactaatgat aaattaatgc ttaagatgtc agaggaggac tttgagcgtg
    25201 ttctcaaaat caatctgaca ggagcattta acatgacaca atcggtctta aagccgatga
    25261 caaaggctcg tcagggtgct atcatcaatg tgtctagtgt tgtcggccta acaggaaata
    25321 tcggtcaagc aaattatgca gcgtccaagg caggcttgat tggctttacc aagtcagttg
    25381 ctcgtgaggt tgcggcgcgt ggcattcggg taaatgcgat tgcaccgggc ttcatcgaat
    25441 ctgatatgac aggtgtcctt tctgaaaaga tgcaagagca aatcttaaat caaatcccaa
    25501 tgaagcgtat tggcaagggg caagaggttg ctcaggcagc aagcttccta gctagtcagg
    25561 attatattac tggtcaggtg cttgccattg acggcggcat gacaatgcaa taaaatagag
    25621 gtattaaaat gacattaaac agagtagttg taacaggtta tggcgtgact tccccaattg
    25681 ggcatactcc agaggagttt tggtcaagct taaaggcagg tcatattggt attaagccta
    25741 tcacaaaatt tgatacgagt gacttcgctg ttaagaatgc agcagagatt caggattttc
    25801 catttgataa gtattttgtc aaaaaggatc taaatcgctt tgacatgtat tccttgtatg
    25861 ccttatatgc tgcgacagag gcgattgaac atgctggcct agatattgaa gcgattgatt
    25921 ctgaccgctt tggtgttatt gtagcgtctg gtattggagg cattcaagag attgaagagc
    25981 aggtgattcg gttacatgaa aaaggaccaa agcgcgttaa gccgatgact ctaccaaagg
    26041 ccttgccaaa tatggcggct ggtaatgttg ccatgaagct gaatgcccaa ggcgtatgta
    26101 agtcaatcaa tacagcctgt gcctcttcaa acgatgctat tggcgatgcc tttcgtacaa
    26161 ttaagtttgg tcttcaagac gtgatgatgg ttggaggatc agaggcagcc attacaaaat
    26221 ttgccattgc gggcttccag agcttgactg ccttgtcaac aactgaggac ccaagccgca
    26281 gctctattcc atttgataag gatcgaaacg gttttatcat gggtgaagga tcaggtatgc
    26341 ttgttttgga aagcttagag catgctcaaa agcgcggtgc gactatttta gctgagattg
    26401 ttggctacgg caatacctgt gacgcttacc acatgacctc accacaccca gaaggacttg
    26461 gtgctcgtaa ggccattaat ctagcattgc aggaggccgg tattgatgca gcagctattg
    26521 actacgtgaa tgctcatggc acctcaactc ctgctaatga aaaaggagaa agtcaggcta
    26581 ttgttgcagt gcttggtaaa gaggttcctg tctcatcaac caagtccttt acaggccacc
    26641 tactaggggc agctggtgct gtggaagcta ttgcaaccat agaagcaata cgtcacaatt
    26701 atgttccaat gacagctggg acaaaggagc tgtcagatga tattgaagca aatgttattt
    26761 ttggccaagg aaaagaagcc gatattcgtt atgccatgtc aaataccttt ggctttggag
    26821 gtcataacgc tgtattagcc tttaagcgtt gggaggatta aaatgaatat tcaagagata
    26881 aaggatttga tggcacagtt tgatgcgtca agcctacgcg aattttcatt caaatcaagt
    26941 gatggggagc tgttatttag taaaaatgag caccgtccga tggcagctcc agctcctgag
    27001 cctgttactt tgcaccagga ggtagcccct attagcctga cgcaggagat tgtctctaaa
    27061 caggaatcaa tccctgcttc ttcaggtctg caagagccag aaggagaagt agttgacagt
    27121 cctcttgttg gtgtggccta tcttgctgcc ggtcctgaca agcctccatt tgttactgtt
    27181 ggtgatagcg ttaaaaaggg acagacattg ttaattgttg aggcgatgaa ggtcatgaac
    27241 gagattcctg ctccttgcga cggtatcgtg acagagattt tagtggccaa tgaggacgtg
    27301 gttgagtttg gacaaggatt ggtacgcatt aaatgatgga tataaaacag attcaagagg
    27361 cattgccaca tcgctaccca atgctgcttg ttgatagaat tttagaggct tcagacgatg
    27421 aaattgttgc catcaaaaat gtcactatca atgagccctt ctttaacggt cattttcctc
    27481 agtatccagt catgccaggt gttttgatca tggaggcctt ggcacaaact gctggcgtct
    27541 tggagctatc aaaagaggaa aataaaggca agcttgtttt ttacgctggt atggacaagg
    27601 taaaatttaa aaagcaggtg gttccgggag accagctagt catgacagct aggtttatta
    27661 agcgtcgtgg gacaatagca gttgttgagg ccaaggcaga ggttgatggc aaattagcag
    27721 ctagtgggac cttgaccttt gcttttgggc agtaaaagac taatcgtctg tggaggaaaa
    27781 aagaacctat gtttaacaaa atcttaattg ccaatcgtgg tgaaatagca gtgcggatta
    27841 ttcgtgcagc acgagaatta ggcatttcca cagttgctgt ttattctgag gctgatagag
    27901 aggctttaca tacgatcttg gcagaccaag ccatctgtat tggaccgtca agatcaaagg
    27961 aatcctatct caatatgaat tctgtcttat cagcagctgt ggtgacaggg gcgcaggcta
    28021 tccacccagg gtttggtttt ttaagtgaaa attcaaaatt tgtgaccatg tgcgaggaaa
    28081 tgaacatcaa gtttattggc ccctcaggag ctgtcatgga taaaatgggc gacaaaatca
    28141 acgcccgcgc tgagatgatt aaggcaggtg ttcctgttat tccaggctca gacggcgagg
    28201 tttacaatgc ccaagaggct cttgagattg caaggcagat tggctatcca gtaatgctaa
    28261 aggctgctgc aggcggtggc ggcaagggaa tccgaaaggt tgaatccgag gctgatttag
    28321 aggctgcttt taacgctgct agtcaagaag ctttaggagc ctttggtaat ggtgccatgt
    28381 atttggagaa ggttatttat ccggcaaggc atattgaggt gcaaatttta ggtgattcac
    28441 aggggcatgt gatacacctt ggagagagag attgctcctt acagcgtaac aatcaaaagg
    28501 tactggagga aagcccttcg attgcgattg gcacaacact gcgtcaaagg atgggtgaag
    28561 ctgctgttcg tgctgccaag gcggtgtcct atgagaatgc tggcacaatt gagttcttat
    28621 tagatgaagc cagcggtgat ttttacttta tggagatgaa tacgcgtgtt caggtagagc
    28681 accccgtaac agagtttgtt acaggcgttg acattgtcaa ggagcaattg cggatcgcag
    28741 caggtcttcc tttatcagtt cgtcaagagg atattgtgat tactggccat gctattgagt
    28801 gtcgtattaa cgcagaaaat ccaagcttta attttgcacc aagccctggt aagattacag
    28861 atctttacct accaagcgga ggtgttgggc ttaggattga ttctgctgtt tacagtggtt
    28921 atacgatacc gccttattat gatagtatga ttgctaagat tatcgttcat ggagataacc
    28981 gatttgatgc tttgatgaag atgcaaaggg ctctgtttga gttagagatt gaaggtatta
    29041 tgaccaatat tgattttcag atggacttga tttcagacaa gcaagtgatt gcgggtgatt
    29101 acgatacgtc gtttttgatg gaaacctttt tacccagcta caataaagat taggagtaga
    29161 tatggcctta tttagtaaaa aagacaaata tatccgtatt actcccaata attctctcaa
    29221 aagctctgtc agtcgtaatg ttccagaggt gccagacgaa ttatttgcca agtgtcctgc
    29281 ctgtaagcac atgatttatc aaaaggatct ggggccggca aagatttgtc cgacctgctc
    29341 ctataatttt aggatttctg ctcaggagcg cttgacttta accgttgatg aaggctcttt
    29401 tcaggaattg tttacagata ttgaaaccaa ggatccatta agatttccag actaccaagc
    29461 caagctgcaa aaggccaggc aggctactgg cttgcatgag gctgtcctga ctggaacagc
    29521 tctggtcaag ggacaaaggc ttgctctagc catcatggat tcgcatttta tcatggcaag
    29581 catggggacc gttgttggtg agaaaatcac tcgcttattt gagctggcta ttagtgagcg
    29641 gctcccagtt gttattttta cagcgtctgg tggagcccgt atgcaagagg gcattatgag
    29701 tctgatgcag atggctaagg tttctgcagc tataaagaaa cattcaaatg ctgggctttt
    29761 ttacctgact atcctaactg atccgaccac aggtggtgtg acagcgagct ttgcaatgga
    29821 gggtgatatg attattgcag agccccagtc cttggttggt tttgctggtc gacgcgtcat
    29881 tgagacgaca gttagagaaa atttaccaga tgattttcaa aaggcagagt tcttaaaaga
    29941 gcatggcttt gttgacgcta ttgtgaagcg gactgacctg cgtgatcgga ttgctcattt
    30001 ggtggcattt catggaggtg tatcatgaca gacgtcgcaa gaatattaaa ggaagcgcgt
    30061 gaccagggtc gaatgacagc tctagattat gccagcctga tttttgatga gtttatggag
    30121 ttgcatgggg atcgtcagtt tgctgatgat ggctctattg ttggtgggat tgcctatttg
    30181 gctgatcaac cggtcacagt gattggtatt caaaaaggaa aaaatcttca agataatctg
    30241 gctagaaatt ttgggcagcc gcaccctgag ggctatcgta aggccttacg cttaatgaag
    30301 caggctgaaa aatttggtcg tccagtgatt acctttatca atacagcagg agcttatccg
    30361 ggcgtaggtg ctgaggagcg cggtcaaggt gaagctattg ctagaaactt gatggaaatg
    30421 agtgacctca aggttcctat cattgctatt attattggcg aaggcggctc aggcggtgct
    30481 ttagctttag ctgttgctga tcaggtttgg atgctggaaa acaccatgta cgctgttctt
    30541 agcccagaag gctttgcctc tattctctgg aaggatggct ctagggctac tgaagctgct
    30601 gagctcatga aaattaccgc agctgagctg tatcaaatgg gcgtcattga tcggattatt
    30661 ccggagcggg gttatttttc gagtgagatt gttgagatga taaaatcaca cttaattgac
    30721 gaaatcactc agctacaggc caagccctta gaggaattat tggatcagcg ctaccagcgc
    30781 tttagaaaat attaaggaca tcaaaaaaga cctctgtaag gctagcagtt agctaggagt
    30841 tacagaggtc ttctttattg ttaggatcaa tctcattaat cggctctttg tccccctaca
    30901 attgataaag agcctttttt gtacatagaa aaaagcccta tcatttctac tgtgtcctta
    30961 tctactacag aaatgataga gcccattaat cgtcttgttg gcaccttatc cggccagtct
    31021 ttggctttaa cgtggcttga tcacctctag tccacccata taaggacgaa gcacttctgg
    31081 aatcgtcact gagccgtcct cattttggta attttctagg atagcagcta cggtacgtcc
    31141 gacagcaagc ccagagccat ttagggtgtg cagtagctta accttgccat ctgcctcatc
    31201 gcggtagcga atttgtgcgc ggcgtgcttg gaaatcttcg gtatttgagc agcttgagat
    31261 ttcgcgatag gtgttttgag cagggatcca aacctctaaa tcataggttt tagcggccga
    31321 aaagcccata tccccagtac aaagagccaa gacacgataa gggagcttta gcttttggag
    31381 aatatgctcg gcattggcgg tcattttttc cagctcttca taagatgttt cgggcttagc
    31441 aaacttaacc atttcgacct tatggaattg gtgtaagcga atcaagccac gagtgtcgcg
    31501 gccagcagag ccagcctcag agcgaaatga tgggctcatt gcagtaaagt agattggcag
    31561 ctccttacca tctatgatgt caccacgata gtaattggtt aatgggactt cagcagttgg
    31621 gataagaaca aagtttgtcc catctagctc aaaggtatcc tccttgaatt ttggatattg
    31681 accagtgcca aacatagagt catgattaac catataagga ggaatgattt cttgatagcc
    31741 ctcttttagg tgctcatcaa gcatgaagtt ataaagggca cgctccagcc ttgcaccaag
    31801 atttttatag aataagaagc gagcaccggt aacctttgcg ccacgctccc aatcaaggat
    31861 atctaaggct tctccaagat cccaatgcgc cttgatgtca aaatcaaact gacgtggctt
    31921 tccccagcga tgaatctcta cattgtcctc ttcatcagct ccaataggaa ctgaatcatg
    31981 gggagtattt ggcaaaacag tgatgatacc ggtaatttct tggtcaatgt cagctagctt
    32041 agcatcaatt gccttgatgt tagcagctag ctgctgcatg tcagcaatct gttggctggc
    32101 gtcttccttt tggcgtttgg cttgagcgat agcagcagag gcgatattac gctgggcttt
    32161 tagctcttct gtttgaacaa gcagggtgcg ccgctgttca tctaaggctt ttagagaggt
    32221 taggatagct tctgacacac cacgtgtttt gagcttagca gcaacagtat caaaatcagt
    32281 acgaatacgc ttaagatcta gcataaataa atctcctttg agctggtgat aagatagtca
    32341 gttataaaat agcatgagca aagctagctg atcgcttttt tatttctgac gagataaaaa
    32401 agcacagcct atgaatacac tggagcgcct aagcgcggtt ccatccagct tcacaatctg
    32461 tgcacttaat tcatatttaa ttggtagacg gtagaatttc gtatgactcc tctatctgtt
    32521 ttcagcaacc acagactctc tgaaagacag agccagacta cttatccgct agacctatta
    32581 taacaaaaaa ggagaaaaag taaactccca aatgagtgtc agctacatca aacgcgcgaa
    32641 ctagttattt tggaattaga gtagacactt tcaatgtttt tcctatagta aagtctataa
    32701 aaaacaagac atatccttga aatacagaaa gctttctttt cttgctaaaa ctttttcatg
    32761 tgtctgtcac ggagcgtcag taatacaaaa ggctgatgac aagtagagct taggtcagag
    32821 gcacaaaaaa tctcgttgtc agacaaaatc aaatcgttaa atattaaaaa ttgtggtaaa
    32881 ctaatattat gcgtaaaaat gtaatgacat tagataagaa ccgccattac ggtttagatt
    32941 tattgcgaat catttccatg tttatgattg tgatcacaca tgttttggga aagggcggct
    33001 tgcggtcaac tgtcgaaggt gaggcagatt cttattttat tgttacctgg atgattcagg
    33061 ttcttgttta tggggcggtc aattgctatg cgttgattag tggctatgtg ggcattaagt
    33121 cgccctataa atattccaaa atcgttaata tttgggtaca agtcttcttt tatagctttc
    33181 tgatgaccct tttgtttgct ctatttggct ttccagttag cttagagaat tggcgtcagg
    33241 ccctctttcc catagtgagt ggcaattatt ggtatatcac cgcctacttt gggttactga
    33301 tttttatgcc tatgatcaat ggtggcctca ataccttatc caataagcag ctaggccgat
    33361 tggtactgct ggtttttgct attttttcgt tgatcccagc tctgatgaac cagcaggtcg
    33421 atgaattttc cttaagcaag ggctttgaaa tgacttggct gattattctc tacattatcg
    33481 gagcctatct aaggaggata gagctaagta ggtttagtca taagcttctt attgcggttt
    33541 atatgggatc tttggtagtt acctatatca tgaaatttat ggtgggaaat atttggtact
    33601 ggtatgtatc acctagcctg accttgggag ctattgcctt atttattctt tttgctaagc
    33661 tgaagctgac atcagaaaca ctgctgctac gctttattgt gatcgtgtct ccaacgactc
    33721 taggtattta tctggtgcac ttacacccct tgctggtcaa atttattatt cgcgattttg
    33781 cagagccctt tgtcaatgct cctatccttt tatacccact actgatattt ggcgtcggca
    33841 ttgtgattta ttttttgtcc tttctggttg aacaggcaag gctgatgctt tttaaaaaac
    33901 taggctttca aaatttgttg aaatgggtgg acaagaaaat cccctttgca gattgatgag
    33961 gaataaggtt agatttagat tgtagaaagg attcacttaa gcttgttttt caagcttttt
    34021 cttttaatca aaaaaacaaa agaattctga aaaatactgt aatatcagca ttttccagag
    34081 ttttcattat atgatagtca atttctaaat tttcaatttt tctatcgctg atagggtttg
    34141 tctacattct gtaagcttgt ttttcaagct tttttgttag caacgaaaaa aactcttaga
    34201 catattgcta tggtgctatg tctaagagta ttatcatgct ggtctatgac cgtaatattg
    34261 aattaaggca ggcccatcaa tgagatttct tatccttttt ttgatgatga aatagctttg
    34321 ctattatggt ctggaccaag gttggtagct tgatgacctt gtcattgcca attgtttctc
    34381 tagcaacctt caagattttt cctgaatcct ttgaagcaaa gagaaatttg ccttgatcgg
    34441 taaagatttc aaagtgacga ctgacctttt tgccagaaac attggcaccg atttggttaa
    34501 tggccgtcca gggaatttga atgaagtcct caacgttttt atcattgtaa aattccaaag
    34561 ccttatctcc aagtaagatt ttcccaacct ttcctccgat tccaagatag gagacggctg
    34621 ttgtctgaag gatcaccctt tgatttaaag attgtgccat aataagtcct ttagtgtttt
    34681 tgtctattat aacataaaaa tatagcttgt agcaggctga atactggcct ttgctaaggc
    34741 tctagacagc caaaaattaa ggaactggga agcccccaat tccttaattt ttattacatg
    34801 atgtgaagaa ggtgtgcgat gataccaaat gcaaacaagg caatgatgat tgcgattggt
    34861 gatacttttt tcttcaataa ccacatgcaa aggaaggtaa gtagtaatcc agcaagtcct
    34921 gggatcaatg agtctaattg cccttgaagg gtttgtgatt gaactttatc aaggctcatg
    34981 ccacccatag cttgtccaag aatacttttt agctcagcac ctttaacggc tccctcaggg
    35041 aagacaacat aggcaccttc agaaagctgc ttgcctggaa ggttgatggt aaagttgata
    35101 gatacccagc gttgtacaag gacagcaagg ataaacatac caaggataga agctccctta
    35161 gtgatgtctt gtaggatacc acctgacatg tctttggtga tttcagatcc agccttgtag
    35221 ccaaattctt gagtgtacca caagaaggcc atacggataa tgttccagcc aaagaagaaa
    35281 aggagtggac cgacaaggtt accagtttgt gcaagagaag caccaagagc accaaggata
    35341 ggacgcactg taaaccagaa gacaggatca ccgatacctg caagaggtcc catcataccg
    35401 atcttaaccc cttggatagc agcgttgtca atagcagtac cgttggcacg ttcttcttca
    35461 agggcaagcg ttaccccgat gataggagca gccacatatg ggtgagtgtt aaagaattcc
    35521 atatgacgct caagtgcagc agcacgatct tctttagttg tgtaaagctt tttaagtgct
    35581 gggataagtg cataagccca acccatgttt tgcatacgct catagttcca agacccttga
    35641 aggaattgtg aacgccacca aacacgttta cggtcagctt ttgttaattt aatttgttca
    35701 gtcattaatc ttaccccttt ctagtagtct tctaggatat cgccgattgg gtcagcagag
    35761 cctgctcgac ctccaccgtt accaccttgt tttgaaaggt taaggtagat aaaggcaata
    35821 gccacaccga taacacccat agcgataagt gttaattggg tcacagctgc aagggcaaaa
    35881 ccaagtgcga agaatggcca tacctcacgt gtagccatca tgttgataac aagagcgtaa
    35941 cctacggcaa caaccatagc accaccgatt tgcatacctt cattcaacca agctggcata
    36001 gccttcaaga cactttgaac ggcctcagtt ggcacagcaa caagaagtgc agctggtaca
    36061 gcaatacgca agccttgaag aagaagtgca gcaaagtgga agcgctcgat agcagagaag
    36121 ttaccctcta aagcagcctt gtccccagcg tgaacaagta cagttgaaat ggtacgaaca
    36181 atcatagtaa ggaaaagacc tgcaaccgca agaggaatag ctgttgagta tgcaaaggta
    36241 atcccttttt gagtaaagtc gccaccctta accatgataa tagccgctgc aacagatgca
    36301 agagcagcgt caggagctac agcagcacca atgtttgccc aaccaagtgc aagcatttga
    36361 agagtaccac caagcataac acctgcttca aggtgaccag tcacaagtcc gattaaggta
    36421 cacgcaacaa gtggttggtg catttgaaat tggtccaaga taccttcaag accggcaaag
    36481 aaggcaacga taacgaccaa gattgcagaa attaatgaaa tatctgacat tttgttatcc
    36541 tttcgtatat gagtcaattg tcaatggaca atataaagcg ttattaagtg atgatgattt
    36601 gtctagaagc aatcatcagg cttatcatat catcgcagca ttgtagatga ggcagacagc
    36661 ttgttgcgtt aaacaagcct acctcttatt tctaaattgc ttattgcaca tttgcttttt
    36721 ggataagctc aaataggttt ttcttagaat catttggcac cttacgaacg tcaaatgaaa
    36781 cacctagatc acgtaatttt tcaaaggcag caacgtcatc cttgtccata gacaatacgt
    36841 tgttaaccat tgttttacct gttgaatgcg ctattgatcc aacgttcagc tctttgatct
    36901 caacgccgcc ttcaatcgca cgaagggcgt cctgaacagt ttcaaacagg ataagagcgt
    36961 gagtgttgcc aaagcgtggg tccttagaag cctcaatcaa tttattgatc ggaacaacat
    37021 tagccttaac cccaccagga gccgcctgct tgatcaattg cttacgaagc tcgtccttag
    37081 ccacagaatc tgacgctaca ataatacgat cagccttaga agctggtgtc catgcagttg
    37141 ctacctgacc atgaagaaga cgagtgtcaa tacgagcaag gttgattttt agcttaccat
    37201 ctccaatgac agttccctta ggaatagctc cttgaagcgc ttgaccacca ccattagctg
    37261 tagaagcctc ctcaactgga ttgagctctt caggaagggc tttaataccg tccttagatt
    37321 ctttaatgat gtttgcggct acttgttcaa cacctgcatt ggcgtccatc aaacgctcag
    37381 tataggcttg aataagcatt ggcaaattta gaccagtgat gatagccatt ttgcgatcag
    37441 gattttctcc tgccacacga ctagcctgat taaatggaga accactccaa aggtcagcta
    37501 gtacaaggat ttcatcatca gcatcaaatt gtgcgatagc attgttgaag tgtccataca
    37561 agtcatctgg tccttcattt ggcatgaaag tcacaacttg aactttctct tgttcaccaa
    37621 aaatcataga accagattga tgaatacctt cagcaaattt accatggctg gcaataataa
    37681 taccgatacc cattcttgtt cttcctcctt attaaaatat ttttcgttga aatgaagaag
    37741 aataatctcc ttccaaatag catttggcaa ttctttttca cttgaacgaa attcaagaac
    37801 gtctctattt taaaacgttt tcacttaaaa atcaagccct ttcggaaaaa tcttacgaaa
    37861 tatgaaaaaa ttttcataat gcgctgccga ataagtagaa tattgataat aaagggattt
    37921 ttatgccgca taaaaaagaa aatatgctga aaaataacga aaatattaga aattctttca
    37981 tcaattgacg gaaacggcat taagaaaacc atcgttttct gaaaaacaat ggtttcgttt
    38041 gctttcacaa gaaaagctct tctagttttc tggcgacccc gtcctcttcg ttagagtaag
    38101 ctagctgctg gtcggcaaag ggcagcagca cagggctggc atttttcatg gcatagccgg
    38161 ttccggcaaa ggccagcatt tctgtgtcgt tatgctcatc accaaaggcg attaaatcct
    38221 taggctcctt gttgtaaatg ctaagcaggt attttaaggt ataggcctta ttaatgtttt
    38281 tgggggacat ctcaaggata tttaagggac caccccaaga gtccacctca atttcgtcct
    38341 tgaagaaggc gcgcatggcc ttggctaggg catacttatc ctcatgatgc gtttgcatga
    38401 gaagagcatt tggatcctgc gtgattttgt cgatctgtaa agccatatct ggtgtgatgg
    38461 cctcaaacca aaaaggttgg ggtcaatgct ctcaggccta ttcatggtaa tgtagaaggc
    38521 ttttcggtac tcactagcaa taaagtccat ctggaagtcc tcctgcactg ctaggagttt
    38581 gagaaggtat gccttatcaa gagtcacatt atgctcgtat ttccatcttt gctcaggtag
    38641 gtgggtcaaa gagccattaa agctaatcat aggtgtcttt agctctagct gaaggtagta
    38701 gtcaatagcc atacgataag gacgtcctgt cgagatgatg acctcatgtc ccttagcttg
    38761 gacggcctta atggtttttt gagtataggt agagatggta ttgtcgtgat gcaataaagt
    38821 cccgtctaaa tcaatagcaa ttagtttttt agtcatacac tagattataa caaattttag
    38881 gatcagtgga agagaaaatt gctgcttgga cggttaatag aaaaaaaggc tgttaaattt
    38941 tgaacgatca tggcaaataa acgaaaaaag ctattgaaaa tagaacgata aaatgttacg
    39001 atgaatatat cgttcgtaaa aacgataata atcatttggt tttaagagaa aaagcttatc
    39061 tgatgagata agggcttttt tgattttgcc tatcaataag gagactccat tcaaatggaa
    39121 aagtttttta agttaaaaga aaatggcacg acggtttcaa cagagctgat ggctggtgtg
    39181 acgacttttt ttgcgatgtc atatatctta tttgttaacc caagtatttt gagtgcagcg
    39241 ggtatgccgt cgcaagcggt gtttttagcg accatcatcg cagctgctat ctctaccttg
    39301 atcatgggtt tgtttgctaa tgtgccttac gcattggctc ctggtatggg acttaatgct
    39361 ttctttactt acactgttgt ttttagctta ggattttctt ggcaggaggc cttggctatt
    39421 gtctttcttt gtggtctgtt taatatcttt atcactgtca caaagcttcg caagagcatt
    39481 atcaaggcta ttccagtaag cctgcagcat gctattggcg gaggtattgg agtctttgtt
    39541 gcttatctag gttttaaaaa tgctaacctg atcacctttt cgctatcatc tgctgagatt
    39601 gttactgtaa atggtgttga gccagctaag gcaactgctg aaacatttgc taatggcgtc
    39661 ttctctgtta atgctaatgg tggtgtggtt ccagctattt caaccttcac cgatccgagt
    39721 gttttgctag cagtttttgg tctgctgcta acagcagtgc ttgtgcttaa gaacgttcgt
    39781 ggagccatcc taattggtat tacagttaca actttagccg gtattcctat tggagtggtt
    39841 gatctttctg ctgttaattt tgcagacaat cacatcagct cagcctttgc tgaattaggg
    39901 acaacattct tggctgcctt tggtggcatg gcgtcactgt ttagtgattc aagtcgcttg
    39961 ccgcttgttt taatgacgat ctttgccttt agtctatctg atacctttga tacgattgga
    40021 acttttgttg ggactggtcg tcgaacaggg attttctctg aggaggatga gagagctttg
    40081 gaaaacagct ctggctttag ctcaaaaatg gaccgtgcgc tctttgctga cgctattggt
    40141 acttcaatcg gagctttatt tggcacctca aataccacaa cctacgttga gtctgctgct
    40201 ggtattgcag agggaggacg tacaggtcta acagctgtat caactgctgt ctgctttgtc
    40261 ttatctgttt tactgctgcc gatcgtggga attgttccag ccgctgcgac tgcaccagcc
    40321 ttaatcattg tcggggttat gatggtatcg tccttccttg atgttgattg gagcgacttt
    40381 gacgttgccc taccgtcctt ctttgctgct ttctttatgg cactttgcta ctctatttca
    40441 tacggtgtgg ctggctcctt tattttctat tgcttggtga agcttgtgaa gggcaaaacc
    40501 aaggagattc acccgattct ttggggagca accttcttat ttgttttgaa ttttatcatt
    40561 ttagcgttat tgtaaacgac taatgaggta cttaggtgcc tcttttttgc tgggacaata
    40621 aagacaggga ttaccgtttg gactgggact atggactttc taagctcata ggcattgcca
    40681 ccttttccta gtcctatatt taggctaagt cttaaggttt tagagctgcg ggttgatttc
    40741 tagagcattc agccctggct atcacagcag aatgccatga tgttaggtcc atgtgatttg
    40801 ctgctggctc ttttgattta tgagatgtta aagctgattg agctttgacg acattatatg
    40861 aggactgacg agcctagaat attttgctga caggctggct taggcttgga agaccgtttt
    40921 ttttctgtta taatagcctt atgttttata gcaaaaatga gaatgaatta atcgcttacg
    40981 ggcaaggcat tggtagacag ctaaaggcag gagatgtgct tgtcttgact ggtgacttag
    41041 gtgctggtaa aacaacgctg accaaggggg ttgctaaggg tttggggatt gatcagatga
    41101 ttaaaagccc aacctatact atcgctcgag aatatgaggg aagactaccc ttgtatcatt
    41161 tagatgttta tcggattggt gatgatccgg actctattga tttagatgat tttatctttg
    41221 gtggtggggt tactgtgatt gagtggggcg agcttttagc caagggaacc ctgcatgact
    41281 accttgaaat tttaataaca aaaacagaaa caggccggca ggttgattat ctagcacatg
    41341 gtcatcgatc agaggcactt cttgaggagc ttaagcatgt ctgagcaggt ggtgacaatc
    41401 gaagaggcca aggcctcaga tgcgtcagct ttgatcactc taattaaaga agctgctgat
    41461 gagacagatt ttatcacagg gactgaggac gtcatagctg ctaccgtaga ggtgcttgag
    41521 tgttttctag aggctagtca ggagtctttg acagatattt gccttttgct aaaggtggga
    41581 gatatattag ctggtctgct aaatatagct ggcaaagcat atcgtgagac tagctatgtt
    41641 ggcgattgct ttatgctggt cttgaaaccc taccgcaatc atggcctagg acagcttttg
    41701 atggagacta cccttgattg ggccagagaa acaaagcagc tttgtgcttt ggagctggag
    41761 gttcaggctc gaaatacttg tgcctatcat atttatgaga aatatggctt taaaatagag
    41821 ggcgtcaaaa gaaaggacgt caaatcaaga aatggagact atcaggatgt ttaccttatg
    41881 cgtaaatatc tggaacgtga atagatgaaa attggaaaaa aaatcttttt aatgctgaca
    41941 gctattgtgc tgttgacctt gggggctatg ggagtttacc taaccaatgc ctataccttt
    42001 tcaactggag aattgtcaaa gacctttaag gattttgcaa cgtcctccaa aaaaagtgat
    42061 gccattcaac agacagagcc cttttcaatt ctattgatgg gagttgacac aggatcgtct
    42121 cacagaacct ctacctggca aggaaatagt gattctatga ttctggttac gattaaccct
    42181 aagaccaaaa agacaaccat gacaagctta gaaagagaca ttctcatcac tttgtcaggt
    42241 ccaaatgata atgagatgaa tggagcagaa gctaagctga atgctgctta tgcagctggt
    42301 ggtgcccaaa tggctatcat gaccgttcag gacttgctga atatcacgat tgacaaatac
    42361 gttcagatta acatgcaagg gctcattgat ttggttaatg ctgttggtgg cattactgtt
    42421 accaatgaat ttgactttcc tatctctatt gcagataatg agcctgagta tcaggctacc
    42481 gttgcaccag gaactcacaa gataaatgga gagcaggcct tggtctatgc tcgaatgcgc
    42541 tatgatgatc cagagggaga ctacggtcgg cagaagcgtc agcgcgaggt tattcaaaag
    42601 gtgctgaaaa agattcttgc ccttaacagt atcagctcct accgaaagat cttgtcagct
    42661 gttagtggta atatgcaaac caacattgaa atatcatcac gaaccattcc taatctttta
    42721 ggctatacag acgcccttaa aaatatcaaa acctatcagc taaagggtga gggagcgacc
    42781 ttgtcagatg gcggctccta tcaaattgtg acctcagatc atcttttaga aatccaaaat
    42841 cgcattcgtg ctgaattagg ccttgaaaag cttagtcagc taaaaacgac tgccacagtt
    42901 tacgaaaacc tttatggctc gttaaaaact cagtctactc aggatagcag ctattattac
    42961 aattcaggta gcctaccggc ctatacagac tcatctaccc agtactcaac ctattcctca
    43021 gagacgtcct ctagcagcag ctatcaggac acaacagctg gtacacaaga gtcaggagca
    43081 gctaatgtga ctcctagccc tcaagcagac tcaccagcag agcagcaatc aagtggtgca
    43141 accactggta cgccagcagc gccttagggt acagccaaaa aaacgaagaa atctcatcaa
    43201 ggcttgatcc tgtgagtgat ttcttcgtct tttttgtaca tacaaaaaga gcccataatc
    43261 cctatagcgg acttgtccac tacagaaacg atagagccct tttttgtcac cttgaggctt
    43321 ggtagtctgc ttaggcttat ggggtttcct gctggtactt gctcatacgt tgttggattt
    43381 cagtcagatg ggcctgagct tcttggttaa aggcctgcca tttgtaggct aattctgttc
    43441 ctgctgcttg aagcgttcga gcctcctttt gaatgatggc gagatttgcc ttaatcctat
    43501 caacatcggc ctggatagcc ttcttagagg tttgcatggc tactagagtt tctttgattt
    43561 gatgacgttt acgatacact tggtaggcta aaacggatgt gagaccaatt gtggtcattg
    43621 tttttagagt cattggctaa tctcctgact aatttgttgt gccaaggctg ctagggctgg
    43681 gaagtcaggc tcatgtgttg tatactgaat agcgatcccg tcttcttggc tgtagcgagg
    43741 aacgaggtgc acatgcgcgt gaaaaacagt ctgaccagct agctcttcat tattattaat
    43801 aatgttcatt gcagtagcac ctgttgcttt ttgaatggcg cgagcgattt taggtaatcg
    43861 ttcaaaggtc tggctagctg tctcggcgtc cattgctagg atatttcgga catgcttttt
    43921 aggaatcaag agggtatgac ccgctgttgt ttgcgaaata tccaaaaaag cgagtacctg
    43981 ctcatcctca taaaccttgg aggagggaat ctcaccgcta ataatgctgc aaaagataca
    44041 attttccatg tgataatcct ttcgtctgcg tagcaatggc tcaaatcagt agttgaataa
    44101 ttttagaata agaaatcagt agttgctcag tgaccatagc tatctcatac tatagttatc
    44161 ttagcatgta ctggtctata ttgcaattgt ttatagctgg tgctaatggt tatcgaccac
    44221 atgactagca aagccttttg aatcatgata atggactaag caattatggt taagcacata
    44281 actaagcctg ctacttgctg caagctaggt ccgtcaaagg tgtgcatttg cgcactatcg
    44341 tacggtagtg acatggcaca atatttgtaa ggacaagagt ttcagagagt atgaggtgct
    44401 ggaacttctt gacagttaag gctgagaaag cttttagaac aaaaaaagat tgaagcgtca
    44461 gcaacatagg ccttatcttc aatcgagtgc ggatggcttt actacaggct agggtcctcg
    44521 ttttgcgaga atttatcagg aacagcccat aggctagggt cctcattttg tgagaattta
    44581 tcaggaacgg cccataggct agggtcctcg ttttgtgaga atttatcagg aacggcccat
    44641 aggctagggt cctcgttttg tgagaattta tcaggaacag cccataggct agggtcttcg
    44701 ttttgtgaga atttatcagg aacagactct tgagcttctt cagagctgac ctgccattcg
    44761 ttagccgtgc ttacttcctg aggcttttca gagatagttt gccagccatc tgtgataacc
    44821 acctcctgtg gcttttcaaa gatagtctgc cattcgttag ccttagcctc tgtttggact
    44881 aggcctgaaa ttgaaagtgc tgaaagtgat accaaaccaa atgttaaaaa gcgtgacaaa
    44941 ttcataacat acctcctttg tcattaaaga cgcaacactt atttacatgt taacgataac
    45001 attatattat taaaaattca atacaataag ataatattat catgattttt tagatgacgc
    45061 cttagatgag ctgctattta ggatcaccag gtcattcgaa tatgatgtga tagatggtta
    45121 ggactgatag atcaagctaa tatagcctct gtttttatag ctaggccttt ttcttgatga
    45181 tcttaaaata gacttcagat tcactcagcg tttttagctg atgggagcat tgatcaaaac
    45241 agttaacgct ctgtgcagaa atttgttata atagctaata taagtgtacc cttagtatta
    45301 gctgccccag ctttcttaag tagggtcaag ctaattggtc ttatcagtgc ttcaaagcgc
    45361 tggataggct gatgatgaca aagcattgcc tagtaagtcc tatctgtcta ggctaataac
    45421 ctgtcatcta gggaagctag tatgcaaagc tacaatagat tagatattag aaagaaatga
    45481 tatgttaaac attgagaatg tcactggagg ctaccttaat attccagttt tgaaggatat
    45541 tagcttttct gtcggaaatg gagagctagt agggcttatt ggtctaaatg gtgctggtaa
    45601 gtcaacaacg attaatgaaa ttattgggtt tttaaagcca tataagggaa ggatttccat
    45661 tgatggctta accttggcgg agcatgaagc tgattatcgc aagaaaattg gctttatccc
    45721 agaaacacca agcctgtatg aggagctgac cttagcagag catatcaata cggtagctat
    45781 ggcctatgat attgatgtgg agctggcaca taagcgagct gagcccttct tagagctgtt
    45841 tcgtttgacg gataagctgg attggtttcc ggtgcatttt tctaagggaa tgaagcaaaa
    45901 ggttatgatt atttgcgctt ttgtcattga ccctagtctt tttattcttg atgagccctt
    45961 tttggggctt gaccccttag caattgctga tttgattaag gctttagagg ttgaaaaggc
    46021 aaagggcaag tcaattctaa tgagtaccca tgtgctggat tcggcagaaa aaatgtgtga
    46081 ccgttttgtg atattgcatc agggacaggt gcgtgcacaa gggactctgg cggatttgca
    46141 ggcagtcttt ggagatgctt cagctagtct taatgacatt tacctagcgc tgacaaaaga
    46201 ggggtaagct atgaaggcat tatttcgtaa gcgtcgtcag gagtttcagc acaagcatac
    46261 caagtatctg ccttatgtct ttaatgatca ttttgttctt gtcttgctgt ttcttttggg
    46321 ctttattctt tttcagtaca gtcaactact caagcatttt cctgctaatc ctctaccgat
    46381 tcagctaggt ttgttgattg ctgtcttgtt tttgcttaat ctggggtcag ttgctaccta
    46441 tcttgaaaag gctgatcagc attttttgct gaccaaggag gcagaggtta ttgcccatat
    46501 caggtcagca gagcgcttgt cctttattct ttggtctagc cttcaaacgg tcttgctgtt
    46561 acctttattt cctttgtttc aaaggcttgg tgtttccttg cttgcctttg tgctattgct
    46621 tggtgttttg gtgctggcta agcgcttact gttaaagcgt aaggtggcaa gctttttgag
    46681 ctccaagggg cttgattggg aaaaagcgat tgcttttgag gcagatcgcc agcaggccat
    46741 tttaaagttt tatgctttgt ttacaaatgt taaaggaatc tcaaccaagg ttaaggaaag
    46801 gccttacttg aatcctatac ttaagcttat caaggcagat agtaaaaagg tttggacaaa
    46861 cctatattta agagcatttt tacgcagctc tgattatcta gggttatggt tacgtctgtt
    46921 gttgcttagt tgcttgtcac ttgcctttat ttccaaccct tatttagcag taggcttggc
    46981 cttggtcttt cattatctaa gtctttttca gttattatca ctttatcatc attatgatta
    47041 ccattatatg agtgggcttt acccgactaa accacagcat aagcaaagga atctactttc
    47101 tttgttgagg caattaagtg gtttgatgct tatcgtcaat cttgtgctct gccgttcttg
    47161 gcaaaatgct cttgtgttga ttgtggcgat gggattatta aatcttcttt acttaccgta
    47221 caagttaaag aagatgattg actaagtcct ttaaaacaag taaaataggg ataactggtt
    47281 acagaagata gaaaaggagg ggataaggtg acaacaaccg aacaggatct tgtattgact
    47341 cccttgcgcg gaaaaagtgg caaagcctac aaagggacct atccaaatgg cgaaagcgtc
    47401 tttatcaagc ttaatacaac accaatccta cctgccttag caaaggaaca gattgcccca
    47461 caattgcttt gggcaaagcg tatggggaat ggcgatatga tgagtgctca agagtggctc
    47521 aatggtcgta ctctgactag agaggatatg aacagtaagc aaatcgtcca tattctgctg
    47581 cgcctccaca agtccaagca gttggttaat caattgcttc agctcaacta taaaattgaa
    47641 aatccttatg accttttagt agactttgag caaaatgcac ctttgcaaat tcaacagaat
    47701 tcttatttac aggctatcgt caaggagcta aagcgcagcc tacctgaatt tcgctctgag
    47761 gtggccacga ttgtacatgg tgatatcaag catagcaact gggtgattac caccagtggc
    47821 atgatttttt tggtggactg ggattgtgtg cgcctaacag atcgaatgta tgatgtggct
    47881 tatttgctaa gccactatat tcctcggtcg cgatgggcag actggctatc ctattatggc
    47941 tataaaaata atgataaggt catgcaaaag attatttggt atgctcaatt ctcttatcta
    48001 actcagattt taaggtgctt tgataagaga gatatggagc atgtcaatca agagatttac
    48061 gctcttagaa aatttagaga aatgtttaga aagaaataat gcgagttaga aaacgaaagg
    48121 gtgcgcagga gcacttggaa aacaatcctc actatgtcat tttagagccg gaggctgcta
    48181 aggggcgctg gtgtgaggtc tttggtaatg atcatccgat ccatattgag gttggctcag
    48241 gcaagggagc ctttatcaca ggtatggcgt tgaaaaaccc agagatcaac tatattggca
    48301 ttgacattca gctatcagtg ctaagctatg ctttagataa ggtcctagcc tctcaggctc
    48361 ctaatgttag gctcttgcgg gttgatgggt caagcctgac caattatttc gatgccggtg
    48421 aggttgatat gatgtatttg aatttttcag atccttggcc caaaagcagg catgaaaagc
    48481 gtcgactaac ctacaaatcc tttttagaca cttataagca gattttgccg gaaaatggtg
    48541 aaattcattt taaaacagat aatcgtggct tatttgagta tagcctagcg agcttttcac
    48601 agtacggtat gaccctcaag caggtctggc tggatttaca tgctagtgat tatcaaggaa
    48661 atgtgatgac tgagtatgag gctagatttg ctaaaaaggg acagattatt taccgcctag
    48721 aagcaacatt ctagtagcta ttttgacaaa aatatgatac actactgagg ttgagttgat
    48781 cagcctttta cttggagagg tcgcatagtg gccgagtgcg cacgcttgga aagcgtgtag
    48841 tccttaacgg ggctcggggg ttcgaatccc ctcctctcct tttatcctat tgatatatca
    48901 aggggttcgg tggtttcacc cgttttttac ccgtcaattt tgagattttg aaaaatgttt
    48961 ttgacctgat ggtcattttt ttcttttaga ctttctatct gatgagcgta aaccttgagt
    49021 gtgatgttga ggttttcgtg acccagcagc ttggatactg atattagatc aacgccctgc
    49081 gctatcaaat aagaagcgta agtatgtctt agcgagtgat tggttagatt tctgccggtc
    49141 actcttttta taactttgtt cgttgcattg tttgacgctc cgaaacagat acgacttagt
    49201 ttattatctt gataatgatt atctttaaaa tattttaata attccacact attgttatca
    49261 atagggacct tcctgatgga ttgctcgttt tttgtaggcc tgaaattttg agaaatcgag
    49321 taatcaaaag ttttattaac atcgacatag ccattgtcaa aatcaatatc tttccatgtc
    49381 aacccttgag cttctgcaaa tcgtaaacct gttatagcta tgatatatgt cgtaaggtat
    49441 gatgggtact tgattttttc cttagcagtc ttgataaaag caaggtattc agattcctcc
    49501 ataaattttt ccgattcttc tttggcgggt ttttgcgacc taacgatggc ttcatcggca
    49561 aaattatccc taataatgcc gtcacgaatg gccattttac aagcaccctt gatttgataa
    49621 tgaaatttat ccagagtttg ttgggctact ttttcgccaa agtcattaag gacttgctga
    49681 taaaaggtgt gtgtgatact cttgagcttc cgagtcccga aataatgttc gatgtgctta
    49741 aagttcttag tatatgtctg ccacgtcttt gcggtaatgt gaggtctttt atatatgtct
    49801 gcccaacgct tgttgtagtc taaaacagta atatctaaaa ggtctgccgt cagcgtgttt
    49861 aaatcagttt ctgcttgctg ggcggcaact tttgcaagtg tttttgtttt aaatccacgt
    49921 tttgattttt ctcttttttt accttgactg tcacgatagg tgatgcgata ctcccacccg
    49981 gaatctaatt ttcgataaaa tgccattgtt ttcacctcat ttttctgtta aaatgggtac
    50041 aagaaaacga gccatttaat gcttttttct tgtatggttt tgcctttcac acaaactttg
    50101 gtcggggagt gtgagaggct ttttttattt aaagaaatta ttaacattta cgtactgagc
    50161 ctgcgtaagc ttagttttta aggttttaac ttctccggtt tgtatatttc ttaaggctac
    50221 cgttgctttt ccaggtattt cttcagaagt ggttgtggca gtagtgttaa tggttccttt
    50281 tttctttcta gccccaccag tcattccacc gacaatggtt ccaacgcctg gtgccaaaac
    50341 tgtacctatt gctgcccctc ctagaacact accagaacgc cctctttgag tagttttccc
    50401 ttttgttact gttttttcaa taattcgtga accatcaaat tgaaggttaa caaactcata
    50461 aagctcagga gtttcagaat aaaaaccaat ataatatttt ccatctatgg tttttcgtat
    50521 ggccgttggt gttcctagtc ctaaatttag ggcagggggt agtatcattt tgctttcttg
    50581 tgaggctttt tttcttagtt cgttagcttt aattgcacca tctttagctt tcccggcagc
    50641 tgctatggca aatcctttta atttagttat atccatgctt atctccttaa ctaattaaaa
    50701 actctaattc ttccttgacc atcacttcgt cagcgattga ggtcagttca tatttttcca
    50761 tgaattggat gtagttgaaa tcctccatat tatcccaata cgatagctct tcttttaaga
    50821 gatggtgtat catacatcta tctgcttgta gctctgcttt ttctttgttt agtttgtaat
    50881 aactcgcagt atgttctctg tgtcctagtt catgatagat gactttgtgt ttatatatac
    50941 cgtcaagata agtgtcaatc gcaatgacgt tgtgtttttt attaaacatt ccgggggtgt
    51001 ttgtacccct accgtcaaag tatactaaat cgattccttt ttcctgacag actgtttctg
    51061 gtgtcatcat agagcagtcc tctctatttt ctatttttga tgcgcgtttc caatatagat
    51121 gtgataagat ctatatcctc gtcgttgagt tcgtggccat cgaagaagaa agtttcttct
    51181 gcatcttttt tcagatcaat tgcgacagaa gcgtgcccat cttgagcaat cttaggatta
    51241 tctgtcctgc caagtaaata gtcggtagaa acattaaagt agttagctat tttttctatt
    51301 gggtctgtat tagccgtttt tttacttttt aaattataaa tatagttttc gctcaaccct
    51361 atatcagttg cgaccttttg gagagatact cctctttttt tagctaaggc ttcaattctt
    51421 gaatacacct caaacattgt catatcaacc tttctgaaag tatgacaaaa aatatttaac
    51481 tttttcgagt aaaaattatt gacttagttc acacgataga gtaaaatagt ttttgtaaga
    51541 tagttagtta gtaaaaaacg aagttaaact ttttacaaat ctttttaaag tagttgggga
    51601 actgcgcaat ataaaagagt tataaaggtt ataactaggt ttttcttatg ccttcatttt
    51661 acattaacgt gtaaaataag tcaacacaaa aatgttattt ttttactaac tttcttactt
    51721 acaaaaataa aacaccacct agctgctatc tagatggtgc tacggaaatt attctgctca
    51781 aactaatagc agtagtcaac aacacttcac cggtatcgtc cccggcactg tagttggagt
    51841 agaaaatgat tctcgatttt gatttcctat tcttcgtcgc ttttgcgagc gacagccagt
    51901 ttgcaatttc tgtggtcgtc cggccaggac gccaatgaag atataggaac ccctattgaa
    51961 tcttgctagt caagtgcggt aggcaaaagg aaaacctaca aacgaatcca tcttctactg
    52021 agacacagtc tccttcaaaa actcggacaa atgatacgtc ctcctttcat acaaagggta
    52081 tttacattat atatttgtaa gtcgaaaaaa tcaagatgga tactgtttga atcgagcaga
    52141 ataacgtttc cgttaagttg ttttaaataa atctacttac tagaaaggag tctaacgcat
    52201 gtcagacaac acggtcgctg ttgaaaaaat taagaagtat ctgcttgaca ataagctaaa
    52261 acaagttgac ttagcagtta cctataataa agaaccgcaa gatgtggcga atatcttagc
    52321 tggaagaaaa aaagatccag catcaaatcg ttttgtcttg aaagttattt cagatttgaa
    52381 aattagatag aagagaatta tatgaaccaa ttgcttaacg caatactaga aaggaacctt
    52441 atgacagacg cagaaaaaca aaactatgat gcccttttca ttaatatttt tgaacgttta
    52501 gaaaaactgg aggaaggcta tgattttagc tccgtagcta caactacggg ggtccaaaat
    52561 agcggcggtg ttcaatatcg tgaatgccaa gaagacggaa ctgtagtcaa aacagtatcc
    52621 aagaggagct taggctactg atgattatat caaaaaagtc cgacgggaat cgggctcaac
    52681 aataatactt atgaggtaat tttatcatgg atagcagatt attacaaatg ctagatgagt
    52741 ttgaagcagg ccttattgat cgcaaggtca aagtcatgaa aatgattaac aatgaaacgg
    52801 aaacttatcc gctagaactc aataaaaagc aagtcagtaa aatgtttggg attgacccta
    52861 aaacatttga cgcaagattt aacagccaca aagatttccc acgtatcgaa acgggaggtc
    52921 gggaaaaata tccacgagac ttggtcattg agtggtatca cagaaattgg agtataacat
    52981 gaacaaacta gaattatttt tattagcgac aacaatcgtc ttagcaatca tcgctagggt
    53041 gcaatatgaa attattaaaa aacataactc acccgagaat aagcgaaaaa tttttaggga
    53101 agtagcttta gaaaacagca agaaatggag tgcagaacgt tatgtctaaa tgggaattac
    53161 aaaaacaact actggaaaat gcgacagatt ttgagagcac agttgaggct ttacttgact
    53221 taaacgagtc tggcgaaata tctgatctgg aactcttact gaacttaaag gataaattca
    53281 gaagctattc caaagaaaaa atacgtatcc ttaatgaaat tctcaagcta ggaggtgcag
    53341 aatgatgaca acttttgaaa agattattaa gaaaattaat cggattgagg gggagttagt
    53401 taaacctgaa gctgaaagac gagatagctt acctatccta tctgctcagt tgggttctat
    53461 taaacaagat ttaaaattga tgctttggat tgagctgcct tcgttaaata atgtggagaa
    53521 atacgaagct ctttatcaag gaaatgattt taaattcagt gaaactttct tagagcgtca
    53581 agcgacaaga aaagcctttt ggagacgatt agctaaggaa acttttaaag aagaccagga
    53641 taggaggaac tttgttaagt tggctgagaa agaatttaaa ggtgcaactt tgtcatggca
    53701 agaatttttg tggggtaaaa agaaatgaat atttcaataa aactcatagg tgaaacccta
    53761 gctggtttaa atgatatttt acgccagggg gggctctctt gctcccaaaa ccaagcctta
    53821 gcagacgcag tttttatatt aacagcttta aaacaagtaa ttgaggagag aaaatgaact
    53881 atttagaata tgcactagtt tatcttgaac gtgagttaga aattattgat aacgaagtta
    53941 tcgaagttga gttgccgggc ggggattggg agtttgtgcc taatccctac tacgagaaag
    54001 gtctacatga tagcccacac tatcgtagtc aggttgctaa agacattctt gatattaaag
    54061 gacttttggg gaggtgaggc tattgattgc atcaaaaaag acggcttagg aaaccgtcaa
    54121 caattataca cacttaaatt ataacacaga aagagagaaa cacaatgatt gaagtaactt
    54181 ttaaagcaga gagcatggca ggtgttttcg atgctatgcg tgaagctctg gatatgccga
    54241 agacagtaac caaggatgtt gttgaagaaa aaccagctcc taaaaagaaa gaagagtctg
    54301 taactttgac attagctgat attaagaaaa tggctaaagc caaggttgaa gaagggaagt
    54361 caaaggacat caaggaagtc ttgaaagaga tgaacgtcgc aaaagttggt gaacttgaag
    54421 aataccagtt tgcggagttt gttgagaagt tggaggctct ctaatgccag tagaaaatca
    54481 cgcactactg tctgcttcta gtgctcacag atggctctat tgccctatgt tacctagact
    54541 ggaagcagac tatcctagcc gcgacaccgt atacactcaa gagggcacaa gcgcccacga
    54601 gctttctgaa atcaaactga tgtacaagtc tggtaaaatc accaagcgta aatttaacac
    54661 gttaaccaag acttttaagg aaaactcaga cttctacaac gaagagatgg aagagatgac
    54721 ggagctttac acagatattg ttatggagca cctaaatgct tatgagaacg ccgaaattga
    54781 acttgaaaaa cgggttgatt ttagcgactg ggtgcctggc ggttttggga cttcggatgt
    54841 cgtcattttg gcggatggag tcattgaaat tattgatctt aagtatggta agggcatgcc
    54901 tgtgtctgct aatcaaaacc cgcagatggg actgtacgct ctaggagctt atgcttccta
    54961 cgatatggtc tatgactttg accgtatcaa gatgactatc attcagccgc gtttagattc
    55021 ggttagttct gttgacattt acgtggagga gttactctac tgggcggata atgttgtctt
    55081 gcctatggcc gctcaagcag acgcaggcat tggtgactgg aacctaagtg aaaaagtatt
    55141 gcagtggtct cctgtcgcag ctaaattggt accaagagcg caagaaaatt gggaattaat
    55201 tgataaatat gactatcagg agcctgtcta tttatctgat gaagccgtcg cagagatcct
    55261 tgacaaagcc tcagctatca agaagtgggt tgagtcagtt gaagcctatg ccttgaaaga
    55321 agcactctca ggaaaagaag ttccaggcta taagattgtc gaaggtagaa gtaatcgagt
    55381 tatcactgat aaagacaaag caattgatat tttacaagat aacggctttg acgatgagat
    55441 ttttaaaccg aaagagctgt tagcaatggg agcccttgaa aagttaatag gtaaaaccac
    55501 ttttgctgat ttattagcag aagtaattga taaaccacag ggcaaacctg tacttgtccc
    55561 tgaaaaggat aagcgcccag caataaacag tttagaacaa gcaattaaag attttgaata
    55621 ggagaaaaat aattatgaca acaacaccaa acacaactaa agtagtgacc ggaaaagtac
    55681 gcctaagcta tgtagcttta ctagagccta aagcctttga aggccaagag gctaagtatt
    55741 caacagttat cttaattcca aaaacagaca aagtcacaat caagaaaatt aaagacgcgc
    55801 agaaagctgc ttatgaggct gccaaggaca ataaactcaa aggggttaaa tgggagcgcg
    55861 ttaagacaac gcttcgtgac ggcgacgaag aaatggatac cgaagagcac ccagagtacg
    55921 ctggacacgt gttcatgtca gtgtcaagta aaactaagcc acaaatcatt gacaagtata
    55981 aaaaccccgt tgactcagcg gatgaagttt actctggcgt ctatgctcgc gtatcactta
    56041 atgcctatgc ttacaacaca gcgggaaata aaggaatctc ttgcggatta aacaacgtcc
    56101 aaattgttgc taaaggagac taccttggcg gccgttcgtc agctgatgca gattttgacg
    56161 agtggaacga agaagaggac gaagacgata ttttatagta gagagcctct ttagaggctc
    56221 ctcattttta aaggagaggt atgagacatt taaatattga tattgaaacc tatagttcga
    56281 atgacatcaa aaatggggtt tacaagtacg ctgacgctga agattttgag attttacttt
    56341 tcgcttactc tatagatggc ggagaagtag agtgccttga tttgacaagg cagtctctac
    56401 ctgaagacat caaagatatg ttatttgatg ataaagtccg aaagcacgcc tttaatgccc
    56461 aattcgaaag agtttgtctc agtcgttacc tcggcctacc ttactatcta gatccttgcc
    56521 aatggcaatg caccatggtg ctggcccaag agttgggtct gccttcaagc ttggaaaagt
    56581 gtgcgctgta tttaaaatta gcacaggaaa aagatacctc gggtaaaaac ttaatcagat
    56641 acttttccct gccttgcaaa ccaagtaaaa ctaacggtgg gagaactaga aatttaccag
    56701 aacacgcccc cgaaaagtgg caaatgttta ttgactactg tatccaagac gttgttgttg
    56761 agatggcaat cgccgaaaaa ctagaatcag ttcctgtgca cgaccgcgaa tgggactact
    56821 acgcctgcga ccagagaatc aacgacagag gcgtggcact tgataaagag ttagttgctt
    56881 cggctttgta ttgtaaagat gttaagatgg aaagtttgtc tggtgagcta aaagccataa
    56941 caggacttgc taacccaaac agtagagctc agttgctacc gtggctaaaa gaacacggtt
    57001 attcggctaa cgggctgact aaagcagatg ttgaacagga acttaagacg gctgaaggag
    57061 aacttaagag agtcttagaa cttaaactac aaaccgctat gtcaagtcta aaaaaatatg
    57121 aagctatgga aagagctatg tgctcagacg gacgagttca tgggctactt cagttttacg
    57181 gggctagccg gacaggaaga tgggcgggca gagttgtcca agtacagaat ttagctagga
    57241 attatataaa ggatctagat gatgccaggg agtatgttaa aaagcgtgac attgatgctg
    57301 tggagatttt atacgatagc cttaatgaca ctctaaagca gctcgtgcga accgctctcg
    57361 tggctaaaga tggctgtacc ttctatgtct ctgacttctc agcgattgag gctagggtga
    57421 ttgcatggtt tgctggagag cagtggaggc ttgacgtgtt ttcgacgcac gggaaaatct
    57481 acgaggcgtc tgccagtcag atgttcggaa ttccaattga ggagattgac aaggaactac
    57541 gccaaaaggg caaaatttca gagttagcac ttggctatca aggaggtcct ggagcgctta
    57601 agcagatggg ggctctaaat atgggagtca aggaagagga gcttcaaggg ttagttgatg
    57661 actggcgcag ggccaataag aaaatcgtcc aattttggaa agacgtacaa agagccgcca
    57721 tcaaagccat caaatcgaga gcaccgataa aacttggaaa actacgattt agataccgga
    57781 aaggtttcct ctttataaca ttgcctagcg gtaggaactt agcttatgca agagccaagg
    57841 ttgagccagg cgactatgga gacaaaatca tctatgaggg ccaaggagat aaggcctact
    57901 tcacagcgca agagacttat ggcggtaagc ttgtcgaaaa tatcgttcag gcgacggcta
    57961 gggatattct agccgaagcg cttctgagaa ttgaagctgc aggctatggt gttgttttcc
    58021 acgttcatga tgaggctatt atcgaaggct caggcctgac aatcgaagag gttaatgatt
    58081 tgatggctca ggctcctgaa tgggcggagg gtcttccttt aaatagcgaa ggctatgtaa
    58141 caaagtatta tatgaaggat tagatagatg aagcaagaaa aactaatagt aaagtcttct
    58201 cccctgcaag agcttcatat cgcaacaggt agttcgcgaa cagctaagac atggaaaaat
    58261 atcacgctaa cttggcagga gctggttgag aggttagaga aacctacagt cacccaagag
    58321 acgtttgcgg agtaccagaa gatgtctcga gcagaaaaag ggcaagcaaa agacgtaggg
    58381 ggctttgtcg gtggatggct aaagcaaggt aagcggaaaa atgaaaacgt tcaaagtagg
    58441 tccttggttg cgcttgacgc agatagccca agtaaagatt tcttagatag gctagacctg
    58501 cttgcggatt atgcctacgt actctacagt actcacagcc actcaaaaaa agctgctaag
    58561 taccgtctta ttatccctac tgaccgttta atgatgcctg atgaatatga gccagtcgct
    58621 agatatttgg ctaaccaact aggcatgtca aactttgatg acacgactta tcaaagcgtg
    58681 cgcttgatgt tctggccgag tcactcaaga gatgcagact ttacgtttaa atataacgac
    58741 gaggcttttc tgagtgttga tgaggtgctt gatacatacc cggactggca tgactcaagc
    58801 ttctggccag aaagcccgac gcacgctgtt aaaagacagc gtgaagctaa aaaacaaggt
    58861 gacccgctta gtaaaaaagg acttattgga gccttttgtc gtaactatga cattagacag
    58921 gccattgcaa cattcttacc tgaggtttat gaagaaggaa cgactcctga taggtacacc
    58981 tacactgatg gctcaaccgc aaacggctta gttatctatg atgatgtctt cgcttatagc
    59041 catcacggga cagatcccgt gggggatacg cttgtaaatg catacgacct tgttcgtatc
    59101 cataaattcg gagagcaaga tagcgaggct aaagataata ctcctactaa taagctacca
    59161 tcaagcaaag cgatgaatgc ttttgtctgt gacttacccg aaattaaaga ttatctaatg
    59221 gcggaggctt taggcgattt cgatgaagag ttaccagtcg aagatgacag aagctggctt
    59281 gaaattgatg agaggggcga accggaggtc aatagttatt tgctagcaac gcagattatt
    59341 aaggaggttc cgatttattg ggatggctta gaatttttac gctacgacgc taaaaaaggc
    59401 atctggttgc caaacgctga ggaatatttg aagagttata tctcaactaa gaaactcggt
    59461 aaaatcacta agattaggca cattagcgaa accattgtag cgattaaagc acaggctttc
    59521 tcaagcgaag tgtttaccga gagtgatctt aacaagatag tgctagtaaa tggagtctat
    59581 gacctgaggg ataacagctt taagactaag tttgatccag aattgcatgc caggtcaagc
    59641 catcccgttg cctatgcccc cgaggcggcc tgtgaaacct ttgagggttt tcttagggag
    59701 accgtcggag ctgaaaatat agatttcatc tttgagtggt ttggctataa cttttatcgt
    59761 gaatacacta ttcaaaaaat gctattcatc tatggcagcg gcggtacggg taaatcaaca
    59821 ctgattaata ttttacgtga aatgataggt gctgataatt attcagccgt gacactgcag
    59881 tacctgatgc aagaacgctt tgcaaaaatc ggcttatatc gtaagacagc caacttcgat
    59941 accgatgcta aacctcaata cttagcagat ggcgcaacgc ttaaaatgtt gactggggaa
    60001 gatacgatac acgcagaccg gaaaaacaaa gagcctatta atttttacaa ttacgccaag
    60061 ctgtcttttg ccatgaatga gctcccacct atgcgagatt tcagtggagg acttaagcgc
    60121 cgcatgatga tccttgagat ggataaggta ttaacgcagg aggttaaggc aaaataccca
    60181 ctagataaga ttatgagtga ggtgcctggt atctttaaca gagcgatgga ggggcttaga
    60241 aatgccttaa gtaagagaga tttcagtatt agtgccagca tgaggtcaag tgtcgagaaa
    60301 tgggaaaaag gcaacgatgt cgtggccatg ttccttgaag acgagtgtga acttggtgaa
    60361 gacttcaaag ttcctgttag ggacgtctac ccagcctata aattctattg tcaggattca
    60421 ggctacaaac ctttagctag gaattcgttt acgcaaagga tgaatgaact gaattttgaa
    60481 aataagaacg caaaaatggg gggcaagacc gtaagatgtt ggataggttt taggataaaa
    60541 ggagaatttt aaagggttac gtttttcaat aaaaaaggta aacaggagac ataaggttac
    60601 gtagttacgc agaattcaga ctgataaaaa attttataag ttgaaaaaaa acgtaactac
    60661 ataactttcc tgaaaaaact ttcctgttta agtcgattta cataactaac gcaactttta
    60721 tgcaacctca aaaaaccttt catagcaata gt
//
LOCUS       DARYNN010000005        56683 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.005, whole genome shotgun sequence.
ACCESSION   DARYNN010000005 DARYNN010000000
VERSION     DARYNN010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 56683)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56683)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56683
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.005"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(140..505)
                     /gene="rplL"
                     /locus_tag="TVB59_000262"
     CDS             complement(140..505)
                     /gene="rplL"
                     /locus_tag="TVB59_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEL1009207.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     GGAEEATKDSFDVELTSAGDKKVGVIKAVREITGLGLKEAKGLVDGAPANIKEGVAAA
                     EAEEIKAKLEEAGATITLK"
     gene            complement(570..1070)
                     /locus_tag="TVB59_000263"
     CDS             complement(570..1070)
                     /locus_tag="TVB59_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEL1009208.1"
                     /translation="MSEAIIAKKAEQVELIAEKMKAAVSIVVVDSRGLTVDQDTVLRR
                     SLRESGVEFKVIKNSILTRAAEKAGLDELKDIFVGPSAVAFSNEDVIAPAKVINDFAK
                     TAEALEIKGGAIEGVVSSKEEIQALAALPNREGMLSMLLSVLQAPVRNVAYAVKAVAE
                     SKEGAA"
     misc_feature    complement(1099..1234)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(1366..2007)
                     /locus_tag="TVB59_000264"
     CDS             complement(1366..2007)
                     /locus_tag="TVB59_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEL1009209.1"
                     /translation="MIEKGKFIASWLWLLALAVLITIYLSWLLYPIEVDYLQLEQAVL
                     MCKKSILHNYNILLTYLTNPFVRELKLASFSASRAGLKHFTDVKMLFHITQLIFSLLM
                     LPTIIYFYQSIKKGRVMLLRRGLIAAALLPIVIACFALMIGFDQFFTLFHQILFVGDS
                     SWLFDPLTDPVIWILPEAFFGHCFALFFFIYEMILWSLIGLSYSNQSSQVAYH"
     gene            complement(2004..2771)
                     /locus_tag="TVB59_000265"
     CDS             complement(2004..2771)
                     /locus_tag="TVB59_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEL1009210.1"
                     /translation="MPYKAYLIDLDGTIYQGKNRIPAGERFIKRLQEKGIPYLLVTNN
                     TTRTPEMVQEMLANQFNVHTGLETIYTATMATVDYMNDMNRGKTAYVIGETGLKSAIA
                     EAGYTEDTENPAYVVVGLDTEVTYEMLSIATLAIQKGALFIGTNPDLNIPTERGLMPG
                     AGALNALLEAATRVKPVFIGKPNAIIMNKALEILKVPRSEVAMVGDNYLTDIMAGIQN
                     DMATILVTTGFTKAKEVPSLPIKPDHVLASLDEWELL"
     gene            complement(2771..3523)
                     /locus_tag="TVB59_000266"
     CDS             complement(2771..3523)
                     /locus_tag="TVB59_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEL1009211.1"
                     /translation="MGLRYSESLKLSFDFCDVKADVKLPLLLAHCLMVSARQSAEIGR
                     GNEVLLQQYGLIWVVTDYDVTIDRMPRFGETVTIETQAISYNKLFCYRQFHIYDQAGH
                     AIMTILSHFALLNPQTRKAAAIPDDLVVPYQADFVKKIKRPIKIDELQDPMVQAYQVR
                     YFDIDMNGHANNSKYLDWMYDVLGYEFLLHHRPCHLTLTYIKEVRPSTQITSGYHLEH
                     LTSYHEIRSSGQLNAQAIIKWQPITTKESETN"
     gene            complement(3534..4664)
                     /locus_tag="TVB59_000267"
     CDS             complement(3534..4664)
                     /locus_tag="TVB59_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEL1009212.1"
                     /translation="MSKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDAYLEALIKE
                     FESYQISSLKTLYIGGGTPTAITANQLDYLLSHLQQHLQLDQLEEFTIEANPGDLTED
                     KIAVLRQSAVNRISLGVQTFNDKQLKQIGRSHTEAQIYTTIASLKEAGFQNMSIDLIY
                     ALPGQTMQQVKENVAKALALDIPHLSLYSLILEHHTVFMNKMRRGKLHLPTEDLEAEM
                     FEYIISEMEASGFEHYEISNFTKPGFESRHNLMYWNNDEYFGCGAGASGYLDGIRYRN
                     RVPIQHYLKAVADGNARLSEEVLTKEEMMEEELFLGLRKKSGVSVSRFQEKFGLSFES
                     RYGPVVRELQNQGLLVEDKDFIRMTKKGLFLGDSVAEKFILD"
     gene            complement(4731..5417)
                     /locus_tag="TVB59_000268"
     CDS             complement(4731..5417)
                     /locus_tag="TVB59_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1009213.1"
                     /translation="MLSSSIRIGGNMIKHRVDRIASQLDELTQKLYLTMIPEYQEGYA
                     NYIYQTDQPDVQRRRIKHINKTFHRLLSESSFYLMPMTQHSAEIIAHDWIYSPAYECY
                     SMTADPEDYQSILSPKARGEHYFQVLRNGVLFGFASFFEQESELEIGLGMAPDTTGQE
                     DGVSFLGSIEAFASTTYPQETYVLNVASFNKGAQSLYQKMGYQPTSSFEQYANGSSHS
                     FVRMEKKKQP"
     gene            complement(5451..6803)
                     /locus_tag="TVB59_000269"
     CDS             complement(5451..6803)
                     /locus_tag="TVB59_000269"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEL1009214.1"
                     /translation="MGKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETERPRV
                     FVARDTRISGEMLEAALIAGLLSVGIEVYKLGVLATPGVSYLVRTEKASAGVMISASH
                     NPALDNGIKFFGSDGFKLADEQELEIEALLDAKEDLLPRPSAEGLGALVDYPEGLRKY
                     ERFLVTTGADLDGLKIALDTANGAASVSARNVFLDLNADITVIGENPNGLNINDGIGS
                     THPEKLQDLVTETASDIGLAFDGDSDRLIAVDENGAIVDGDKIMFIIGKYLSEKGLLA
                     KNTIVTTVMSNLGFHKALDSCGIHKKVTAVGDRYVVEEMRQFGYNLGGEQSGHVIIMD
                     YNTTGDGQLTAVQLTKIMKETGKTLSELASEVTIYPQKLVNIRVDNSMKERAMEVPAI
                     AEVIAQMEGEMAGNGRILVRPSGTEPLLRVMAEAPSNEEVDYYVDTIAAVVRAEIGLD
                     "
     gene            complement(6856..7812)
                     /locus_tag="TVB59_000270"
     CDS             complement(6856..7812)
                     /locus_tag="TVB59_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEL1009215.1"
                     /translation="MKRFLNSRLGLGLVSIFFAIILFLTAASSSHNHSNSQIYSPIET
                     YTHSLKDVPIDIKYDSDQYFISGYSYGAEVYLTSTNRIKLDSEVNSDTRSFKIVADLT
                     KSKPGTATVTLKVINLPTGVTATVSPDKISVTIGNKKTKTFPVRGSVDSKQLAKGYEI
                     SKIETGIDKVEVTSDESTIALIDHVVAKLPDDQVLDANYSSRVTLQAVAADGTILASA
                     IDPAKANLSVSVKKITKSVPIRVEAVGLMDDSLSDIQYKLSKQTAVISGSREVLETID
                     EVVAEVNISDVTKNTSKTVSLVSNQVSIEPSVVTVQLTTIKK"
     gene            complement(7809..8660)
                     /locus_tag="TVB59_000271"
     CDS             complement(7809..8660)
                     /locus_tag="TVB59_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEL1009216.1"
                     /translation="MSNLSSIDTKFLLSLIDDPLMLVVHLLDILIVAYLIYRFIKSLA
                     GTKIMSLVQGVIFFIIIRVIAEWIGFTTITYLMNQVITYGVIAGVVIFAPEIRAGLEK
                     FGRSTQVFLQKQSLSDEEMLVDALLKSVAYMGPRKIGALIAIEQTQTLQEYIATGIPL
                     NADISSQLLINIFIPNTPLHDGAVIVANNKIAAACAYLPLSESMSISKEFGTRHRAAI
                     GLSENSDAVTIIVSEETGAVSIARKGQFLHDLSTEELEAVLKTHLMNEPGATLPWYKK
                     ILGGKAK"
     gene            8762..10105
                     /locus_tag="TVB59_000272"
     CDS             8762..10105
                     /locus_tag="TVB59_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEL1009217.1"
                     /translation="MKLKTLLAIAAGRTAQLILNKIGRGSTYPGRLALMWDKDILDTL
                     AKDYEIVVVTGTNGKTLTTALTVGILKEAFGEVLTNPSGANMMTGITSAFLSAKRKKT
                     GKPIAVLEIDEASLARVTTYIKPSLFVYTNIFRDQMDRYGEIYTTYQMIVDGASQAPK
                     ATILANGDSPIFASKDLVNPVKYYGFDTPKHEPRLAHYNTEGILCPKCEQILRYRLNT
                     YANLGDYTCLNCDFQRPKLDYKLTQLTSITHHSSAFVIDDQTYRINVGGLYNIYNALA
                     AVAVAEFFGISADQIKAGFNKSKAVFGRQETFSINGKACTLVLIKNPVGASQALEMLR
                     LADYPFSLSVLLNADYADGIDTSWIWDADFELINQMDITEINAGGVRHSEIARRLRVT
                     GFDEAKITSFDKLEGIMQAIENQEAEHAYILATYTAMLAFRELLASRHIVEKEMI"
     gene            10105..10893
                     /locus_tag="TVB59_000273"
     CDS             10105..10893
                     /locus_tag="TVB59_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEL1009218.1"
                     /translation="MTYTSLQSPENRDYQYDLHIAHLYGNLMNTYGDNGNVLMLKYVA
                     EKLGAKVRVDIVSIGDTFDQDDYDIVFFGGGQDYEQAIVARDLPSKKEALAAYIHQNK
                     VLLAICGGFQLLGQYYIQANGLKINGIGVMGHYTLNQDNNRFIGGIKIHNDDFDETYY
                     GFENHQGRTFLSDDEKPLGRVIYGNGNNKEDQTEGVHYKNVYGSYFHGPILSRNVSLA
                     YRLVTTALKEKYGSTVSLAAYDKILQHETSEEYADVKSKASFDS"
     gene            complement(11517..12506)
                     /locus_tag="TVB59_000274"
     CDS             complement(11517..12506)
                     /locus_tag="TVB59_000274"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007893175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEL1009219.1"
                     /translation="MKYIVNKSHNPAFNIALEAYAFRELVDEDELFILWINEPAIIIG
                     KHQNTIQEINKEYIEQHGIHVVRRLSGGGAVYHDLNNLNYTIISNKTTEGAFDFKTFS
                     QPVIETLADLGVKANFTGRNDIEIDGKKICGNAQAYYKGRMMHHGCLLFDVDMTVLGD
                     ALKVSKDKIESKGVKSVRARVTNILNELPEKISVEAFSDKILVKMKETYPDMTEYVLS
                     EDELAKIQQSAEEQFGSWDWTYGKAPEYTIERNVRYPAGKISTFANVENSVIKNLKIY
                     GDFFGIKDVQDIESLLIGCKYEYADVLERLQTIDTTQYFSRMTVEEVAKAIVA"
     gene            complement(12748..14517)
                     /gene="lpdA"
                     /locus_tag="TVB59_000275"
     CDS             complement(12748..14517)
                     /gene="lpdA"
                     /locus_tag="TVB59_000275"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEL1009220.1"
                     /translation="MAVEIIMPKLGVDMQEGEIIEWKKQEGDTVSEGDILLEIMSDKT
                     NMELEAEDSGVLLKIIRQAGETVPVTEVIGYIGAAGEAIDVSSPAAADVNVARTTEDL
                     QAAGLEVPKAPDQGSAPSAPKAELAADEYDIIVVGGGPAGYYAAIRGAQLGGKIAIVE
                     KSEFGGTCLNVGCIPTKTYLKNAEILDGIKIAAGRGINLASTNYTIDMDKTVDFKNTV
                     VKTLTGGVQGLLKANKVTIFNGLGQVNPDKTVTIGVQTIKGRNIILATGSKVSRINIP
                     GIDSKLVLTSDDILDLREMPKSLAVMGGGVVGIELGLVWASYGVEVTVIEMADRIIPA
                     MDKEVSLELQKILSKKGMTIKTSVGVSEIVEANNQLTLKLNNGEEVVAEKALLSIGRV
                     PQMNGLENLNLEMDRNRIKVNDYQETSIPGIYAPGDVNGTKMLAHAAYRMGEVAAENA
                     MHGSTTRKANLKYTPAAVYTHPEVAMVGLTEEQAREQYGDVLIGKNSFTGNGRAIASN
                     EAHGFVKVIADAKYHEILGVHIIGPAAAEMINEAATIMEAELTVDELLLSIHGHPTFS
                     EVMYEAFADVLGEAIHNPPKRKK"
     gene            complement(14726..16135)
                     /locus_tag="TVB59_000276"
     CDS             complement(14726..16135)
                     /locus_tag="TVB59_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEL1009221.1"
                     /translation="MAVEIIMPKLGVDMQEGEIIEWKKQEGDTVSEGDILLEIMSDKT
                     NMELEAEDSGVLLKITRQAGETVPVTEVIGYIGAAGESVDNSTASSEKTTEIPVPTSA
                     EANTTTVPKEAASTAPQVASVANAPAFGEKVRATPAARKAASEMGIELNQVPGTGPKG
                     RIHKEDVEGFKGAQPKATPLARKIAADKGVDLAAVVGTGIGGKITKEDILAVLGAAAP
                     AVEKASIAEEKPAKELPEGVEIKKMSAMRKAISKGMTHSYLTAPTFTLNYDIDMTEMI
                     ALRKKLIDPIMAKTGLKVSFTDLIGLAVVKTLMKPEHEYMNASLINDANDIELHRFVN
                     LGIAVGLDDGLVVPVVHGADKMSLSEFVLASKDVIKKAQGGKLKATEMSGSTFSITNL
                     GMFGTKTFNPIINQPNSAILGIGATIPTPTVVDGEIVARPIMAMCLTIDHRLVDGMNG
                     AKFMVDLKKLMENPFELLI"
     gene            complement(16259..17257)
                     /locus_tag="TVB59_000277"
     CDS             complement(16259..17257)
                     /locus_tag="TVB59_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEL1009222.1"
                     /translation="MTETKLMALREAINLAMTEEMRKDDTIYLMGEDVGVYGGDFGTS
                     VGMIEEFGAKRVKDTPISEAAIAGAAIGSAITGLRPIVDLTFMDFITIALDAIVNNGA
                     KNNYMFGGGLITPATFRVASGSGIGSAAQHSQSLEAWLTHIPGIKVVAPGTANEAKGL
                     LKSAIRDNNIVIFMEPKALYGKKEEVNQDPDFYIPLGKGDIKREGTDVTIVSYGRMLE
                     RVLQAAEELAADGINVEVVDPRTLIPLDKELIINSVKKTGKLMLVNDAYKTGGFIGEI
                     AAMVTESEAFDYLDHPIVRLASEDVPVPYARVLEQAILPDVAKIKAAIVKMVNKGN"
     gene            complement(17337..18305)
                     /locus_tag="TVB59_000278"
     CDS             complement(17337..18305)
                     /locus_tag="TVB59_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEL1009223.1"
                     /translation="MVTVSKEQHLDMFLKMERIREFDSRINKLVRRGFVQGMTHFSVG
                     EEAANVGAVAHLTYDDIIFSNHRGHGQSIAKDMDLNKMMAELAGKVTGVSKGRGGSMH
                     LADFEKGNYGTNGIVGGGYALAVGAALTQQYKGTNNIVVAFSGDGATNEGSFHESVNM
                     AATWKLPVIFFIINNRYGISMSINNATNTPHLYTRAEAYGIPGFYCEDGNDVMAVYET
                     MSKAVEHVRGGNGPAVVEVESYRWFGHSTADAGKYRTKEEVDEWKEKDPMLKYRAYLT
                     GEGIATDEELDALQAQVKQEIDDAYEFAQNSPDPDISVAFEDVWVD"
     gene            complement(18811..20721)
                     /locus_tag="TVB59_000279"
     CDS             complement(18811..20721)
                     /locus_tag="TVB59_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEL1009224.1"
                     /translation="MIILQGNNIERSFSGEVLFQNLSLQVGERDRIALVGPNGAGKST
                     LLKILVGEEEPTSGEVSRKRDLTLSYLAQNSRFESDKTIYQEMLKVFAELRVDEQRLR
                     QMEADMASRSGQALDQLMSDYDRLSESFRLRNGFTYESDIRAILNGFKFDESMWEMKI
                     SELSGGQNTRLALAKMLLEKPELLVLDEPTNHLDIETIAWLEHYLVNYQGALIIVSHD
                     RYFLDKVATITLDLTKNSLDRYVGNYSRFIDLKAEKLAAEEKHYDKQQKEIAKLEDFV
                     QKNIVRASTTKRAQARRKQLEKLERLDKPSSSRKSASMTFQIDKPSGNVVLQVTDAAI
                     GYNDHILAEPIHLDVRRLDAIAIVGPNGIGKSTLLKSIIGEIPLIKGTCHYGTNVETG
                     YYDQTQSHLTGSNSVLEELWRDFPTTAELEIRSRLGAFLFSGEDVKKSVAMLSGGEKA
                     RLLLTKLSMKKDNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     KVLEITEAGSTLYLGDYDYYVEKKAEREELARLAAADHVVETDVAEAAVTDYQLQKAS
                     QKEYRRLTRRFEEIEQTLEGLEAQAKAIEAQMLVSNDTTQLIDWQKELDQLNQKQETL
                     LLEWEDIAGQLE"
     gene            complement(21131..21916)
                     /locus_tag="TVB59_000280"
     CDS             complement(21131..21916)
                     /locus_tag="TVB59_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEL1009225.1"
                     /translation="MASISIEYHSEILAMERHVKVIYPDQSELSPEEQGYQDIPVLYL
                     LHGMGGNENSWQKRTNIERLLRHTNLIVVMPSTDLGWYTDTTYGMNYYQAIAEELPRL
                     LASFFPNMTTKREKTFVAGLSMGGYGAFKWALKSNRFSYAASFSGALHFSPEMLLQQG
                     IGELPYWQGVFGDLNAPDIKKHYLTSIAAESDGQTQLYAWCGYEDFLFEANEKAVAEL
                     RRLGLTIDYRKDHGRHEWYYWNQQLEALLDWLPIAYHKEERLS"
     gene            complement(22022..23683)
                     /locus_tag="TVB59_000281"
     CDS             complement(22022..23683)
                     /locus_tag="TVB59_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEL1009226.1"
                     /translation="MTDINIIALGGVREYGKNFYLVEINDSMFILDAGLKYPETEQLG
                     VDLVIPSLDYVIENKDKVQGVFLSHGHADAIGALPYLLAEVPVPVFGSELTIELAKLF
                     VKANNSTKRFKNFHVVDSDTEIEFKDGLVSFFKTTHSIPESLGVVIGTDKGNIVYTGD
                     FKFDQASREGYQTDLARLADIGKEGVLALLADSANATSNEQTASEAEVGEEMDKVIAH
                     ADGRIIIAAVASNLVRIQQVFDSAAAYSRRVVLTGTDAENIVRTALRLKKLVIADEKL
                     LIKPKDMSKFEDHELIVLEAGRMGEPINSLQKMAIGRHRHVQIKDGDLVYIVTTPSAA
                     KEAMVARVENLIYKAGGSVKLITQHLRVSGHANARDLQLMINLVKPKYLFPIQGEYRD
                     LAAHAHLAEEAGILPENIHIMKRGDIMVLDEDGFLHEGAVPASDVMIDGNAIGDVGNI
                     VLRDRKVLSEDGIFIVAITVSKKEKRIISKAKVNTRGFVYVKKSRDILRESAELVNTT
                     VGNYLQGDHFDWSELKGSVREELSRFLFEQTKRRPAILPVVMEVR"
     gene            complement(23893..24651)
                     /locus_tag="TVB59_000282"
     CDS             complement(23893..24651)
                     /locus_tag="TVB59_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1009227.1"
                     /translation="MRKIIELIHATVEVNNGFDETKAILDDVSLTIYEHDFLTILGGN
                     GAGKSTLFNVIAGTLLLSKGQIKLLGHDVTHLPAEKRASYLSRVFQDPKMGTAPRMTV
                     AENLLIARQRGERRGLSSRRISHYMADFADLVKRVGNGLENHLETPTGLLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSQALMALTDDFVAKDRLTALMITHHMEDALNY
                     GNRLIVMKNGKIIQDLDQKRKSQMTIADYYQLFD"
     gene            complement(24648..25517)
                     /locus_tag="TVB59_000283"
     CDS             complement(24648..25517)
                     /locus_tag="TVB59_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1009228.1"
                     /translation="MIISSVSQGLLWGILGLGIYLTFRILNFPDMTTEGSFPLGGAVA
                     VTLLNLGLNPILATLAAMLAGALAGFATGLLYTKGKIPTLLAGILVMTSCHSIMLMVM
                     GRANLGLHDIKRIQDYLPFAADTNVLVAGLVVATLVIFLLMYFLYTNIGQAYIATGDN
                     RDMAKSFGIHTDRMELMGLAISNALIALSGALVSQQDGYADVSKGIGVIVIGLASIIV
                     GEVLYSTGLTLLERLIAIVVGSILYQFLISVVIALGFNTNYLKLFSAIILALCLMVPV
                     LKKAIIKEASLSR"
     gene            complement(25531..26526)
                     /locus_tag="TVB59_000284"
     CDS             complement(25531..26526)
                     /locus_tag="TVB59_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEL1009229.1"
                     /translation="MKHKGLIVTVIALFLMVAASLVLKEGKKQPQLASKRVVKVGILQ
                     LVTHEALDQIAQGIKDELKKHHQPEQKVSITLMNAEGDQSKIQTMSKQLVKTNDIVVG
                     IATPAAQGLAAATKTIPVVMSAISDPVGAKLVKHLDRPEANVTGLSNKVPVRQTVDLI
                     KEMTPQVKRVGVLYASSEDNSISQVKDFTALAEKQGLEVLAYAVPSTNEVTTTMSVMT
                     EKVDAVFIPQDNTIASAFSAVIVASNAAQLPVYSSVDTMVEQGSLASISQSQYQLGVE
                     TARQVLQLMAGKEVSEVPVEVVDDGKPFLNLKAARDLGLMISKDLLKRSDLTGKQ"
     gene            26878..28548
                     /locus_tag="TVB59_000285"
     CDS             26878..28548
                     /locus_tag="TVB59_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NFACT family protein"
                     /protein_id="HEL1009230.1"
                     /translation="MSFDGFFLHHLTQELNHSIVNGRIQKVNQPFDNELVLTIRNHRQ
                     TYKLLLSAHPVFGRIQLTQTDFQNPQFPNTFTMIMRKYLQGAIIEGFEQIDNDRIIEM
                     TVSNKNEIGDAIKTTLIIEIMGKHSNIILVDRHENKIIESIKHVGFSQNSYRTILPGS
                     AYIEPPKTTAVNPFTISDIALFEVLQTQELSAKNLQKHFQGLGRDTAQELSSLLTTDK
                     LKRFRDFFQRPSQPSLTQTSFAPVAFSNTLKTFQNLSQLLDYYYHDKAERDRINQQAS
                     DLIHRVQNELEKNRSKLIKQEAELLATENAEDFRQKGELLTTYLSLVPNDQDSVELDN
                     YYTGQKITIALDKALTPNQNAQRYFKKYQKLKEAVKHLSGLIADTQQTIAYFESVDYN
                     LSQATIDEIEDIREELIQAGFVKSRKHNKHHKRKKPEQYLASDGKTIIMVGRNNLQNE
                     ELTFKMAKKGELWFHAKDIPGSHVIIKDNLSPSDEVKTDAAELAAYYSKARLSNLVQV
                     DMIEAKKLHKPSGAKPGFVTYTGQKTLRVTPIESKIQAMKCSPSASSS"
     gene            complement(28637..29875)
                     /locus_tag="TVB59_000286"
     CDS             complement(28637..29875)
                     /locus_tag="TVB59_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEL1009231.1"
                     /translation="MLNSEKMIASLEQQDLEQAESYFQRALQEDDAETLLALAEYLES
                     IGFLLHAKTIYLQVCEAYPEVNINLAQIAAEDNVIEEAFMYLDRIPEDSADYLSALLV
                     MADLYDLEGLTDVAREKLLQAAELSQEPIVIFGLAEIEMSLEHFSEAIEQYARLDNRH
                     ILELTGISTYQRIGRAYAYLGKFEAAVEFLEKALAIEYDDETVFELATILYDQAAYQK
                     ANLYFKQLETMNADFLGYEYPYAMSLREEHRTEEALRLVQQGLRKNAFDPQLLLLASQ
                     LAFELHDPAGSERYLLRAKEVAVDDEEVIMRLSSLYLDMERFEEVIALEHEEIDHVLT
                     KWNLAKAYQALEQQEKALTIYKDIEGDLKENPDFLQDYAYLLREFGYTDQAVKQAKRY
                     LQQVPDDIHMQGFLDDLRDD"
     gene            complement(29865..31046)
                     /locus_tag="TVB59_000287"
     CDS             complement(29865..31046)
                     /locus_tag="TVB59_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEL1009232.1"
                     /translation="MSLHSKPNHHDSLFYKWFLNNQAVMVLLITLLVFLTIFVFTKIS
                     FLFTPILSFLAIIMLPLVISTILYYLTKPLVDMVEKLGPNRTASIFIVFGLVILLFFW
                     AISGFIPMIQDQLRSFVEDLPKYVAKVNLEANKLLENEWLVSYRSNLQDMLTSMSQKA
                     LDYAQSFSKNAIDWAGNFAGAIARITVAIIMSPFILFYFLRDSGHMKNGLVNVLPIKL
                     RQPMARVLGEINKQLSGYVQGQVTVAIVVGLMFSVMFSLVGLNYSITFGIIAGFLNMI
                     PYLGSFLAMIPVVIMGMVQGPLMLIKVLIIFVIEQTIEGRFVAPLVLGNKLSIHPITI
                     MFLLLTAGSMFGVWGVFLVIPVYASVKVVVKELFDWYKDITGLYEEEPTEAERVAEDV
                     K"
     gene            complement(31109..31585)
                     /locus_tag="TVB59_000288"
     CDS             complement(31109..31585)
                     /locus_tag="TVB59_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017285310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEL1009233.1"
                     /translation="MTKLATICYIDNGEALLLLHRNKKENDVHQGKWISVGGKLEPGE
                     SPDDCARREILEETHLLVKAMDFKGVITFPDFTPGHDWYTYVFKVTDFEGDLIADEES
                     REGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFRYDDHNKLVEKTVTFY"
     gene            complement(31763..32809)
                     /gene="rfbB"
                     /locus_tag="TVB59_000289"
     CDS             complement(31763..32809)
                     /gene="rfbB"
                     /locus_tag="TVB59_000289"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003002700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HEL1009234.1"
                     /translation="MSEYKNIIVTGGAGFIGSNFVHYVYNHHPEVHVTVLDKLTYAGN
                     RANLEEILGDRVELVVGDIADAELVDKLAAKADAIVHYAAESHNDNSLNDPSPFIYTN
                     FVGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTADTNYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSTGVWAILTKGRIGETYLIGADGEKNNKEVLELILDKMGQPKD
                     AYDHVTDRAGHDLRYAIDSTKLRQELGWEPQFTDFSEGLEQTIQWYTDHQDWWRSEKE
                     AVEANYAKTQEVIR"
     gene            complement(33001..33597)
                     /locus_tag="TVB59_000290"
     CDS             complement(33001..33597)
                     /locus_tag="TVB59_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007893267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HEL1009235.1"
                     /translation="MTEQFFDKALACREIEAIPGLLEFDIPVRGDNRGWFKENFQKEK
                     MIPLGFPEQFFAAGKLQNNISFSRKHVLRGLHAEPWDKYISVADEGKVLGAWVDLREG
                     DSFGHTYQTVIDASKGIFVPRGVANGFQVLTDKVAYTYLVNDYWALELKQKYAFVNYA
                     DPSLGIAWESLEQAEVSEADKSHPFLEAVKPLRQEDLS"
     gene            complement(33597..34466)
                     /gene="rfbA"
                     /locus_tag="TVB59_000291"
     CDS             complement(33597..34466)
                     /gene="rfbA"
                     /locus_tag="TVB59_000291"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HEL1009236.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPIYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLPRFEELLGDGSEFGISLSYKEQPSPDGLAQAFIIGEEFIGDDRV
                     ALILGDNIYHGNGLTKMLQKAAAKEKGATVFGYQVKDPERFGVVEFDDEMNAISIEEK
                     PAVPKSHFAVTGLYFYDNDVVEIAKSIKPSARGELEITDVNKAYLERGDLSVELMGRG
                     FAWLDTGTHESLLEAAQYIETVQRLQNAQVANLEEIAYRMGYITKEDVYQLAQSLKKN
                     EYGQYLLRLIGEA"
     gene            complement(34523..35632)
                     /locus_tag="TVB59_000292"
     CDS             complement(34523..35632)
                     /locus_tag="TVB59_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEL1009237.1"
                     /translation="MTTIAIIGAGIVGSSAAYYLKKQGYQQVTIFDDGNGQATKAAAG
                     IICPWFSKRRNKAWYQLARLGADCYQDLIKELQKEGLSTHFYKQTGVYLLKKNEDKLE
                     ELYQLAIRRKQESPLIGDLAIRCRSDIRVDFPDLQGFEQLVWASGAARVDGADLCQCL
                     LEASGYQVVKKRVGISIEKQGYLVDGMVFDRLILAAGAWLPELLEPLGYQVDIRPQKG
                     QLIDYHIANVTTDNYAVVMPEGELDIIPFEHDRLSVGASHENDKGYDLEPDVAVLEAL
                     EQEALTYYPKLSSASDVSYRVGIRAYTRDFSPFFGQVPQLPGVYAASGLGSSGLTLGP
                     LIAQQLIALLLGQKASLDTSQYPIHHYIRRINDKK"
     gene            complement(35687..36475)
                     /locus_tag="TVB59_000293"
     CDS             complement(35687..36475)
                     /locus_tag="TVB59_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019781659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEL1009238.1"
                     /translation="MKARTIIEKYESYCPLELSMSGDVCGLQIGSLDKEVKRVMITLD
                     VRENTVAEAIAAKVDLIITKHAPIFKGLKDLVSSPQRDIVLELVKHDISVYVSHTNID
                     IVSDGLNDWFCELLGIEQTEVLVETQDGYGIGRVGNVAEQSLEELGLTVKEAFGLDVV
                     RLVRYTGQNPLISRVAICGGSGDKFYQAALAKGAQVYITGDIYYHTAQEMLTEGLLAI
                     DPGHHIESLFIDKLLAKMQAWKKEEGWQVTIMASKASTNPFSHL"
     gene            complement(36465..37151)
                     /locus_tag="TVB59_000294"
     CDS             complement(36465..37151)
                     /locus_tag="TVB59_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEL1009239.1"
                     /translation="MESHLSKRLRHVASYVPDGAKLLDVGSDHAYLPIFLVETEHIQE
                     AIAGEVVKGPFVSALKNVSQYGLTEHIEVRLANGLAAFEARDAVDCITICGMGGRLIA
                     DILAAGKEKLQGIERLILQPNNREDELRAWLSANAFCISAETIMTENGKYYEIIVAEP
                     GQQSLTDQEQRFGPFLSQERSSVFVAKWQKERDKLVYALSCVPATKPVERASISQKIK
                     AIEEVISHES"
     gene            complement(37225..37887)
                     /gene="nth"
                     /locus_tag="TVB59_000295"
     CDS             complement(37225..37887)
                     /gene="nth"
                     /locus_tag="TVB59_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEL1009240.1"
                     /translation="MRIGRERLKKVLSIIGEMFPEAKGELNWDQEKPFQLLITVILSA
                     QTTDKAVNKVTPKLWQSYPELSDLAQANVSDVEDHLRTIGLYKNKAKNIIKTAQQLLT
                     QFDGQVPKTHKELESLPGVGRKTANVVLAEIYGVPAIAVDTHVSRIAKRLNISAPDAD
                     VTEIEADLMAKLPKKDWIITHHRLIFFGRYHCLAKHPKCDTCPVQSYCSYYKTTYGKK
                     KV"
     gene            complement(37887..38564)
                     /locus_tag="TVB59_000296"
     CDS             complement(37887..38564)
                     /locus_tag="TVB59_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEL1009241.1"
                     /translation="MSFLEHYQSGNLVLPTALLFHYKDIFKSSDDFLVWQFFYLQNTT
                     RLDELAPSQIANALGKSVAEVNKAISSLTSQGLLDMKTIELAGEIEIIFDASPVLVTL
                     DQLLARDEKGEHEQQNTNQLKLLVDEFERELGRFLSPMELEDLEKTIHDDQTDLDLVR
                     EALREAVFNGKTNWKYIQAILRNWRKEGITSLRQLEEKKRAREDMTASEVTVSDDFLA
                     AMNLWSN"
     gene            complement(38631..39149)
                     /locus_tag="TVB59_000297"
     CDS             complement(38631..39149)
                     /locus_tag="TVB59_000297"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEL1009242.1"
                     /translation="MDLTQYIASIENYPKEGITFRDISPLMASGKAYSYAIREIVQYA
                     CDKDIDMIVGPEARGFIIGCPVAVELGIGFAPVRKPGKLPREVISASYEKEYGLDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIDLVEKLGGIVAGCAFLIELDGLNGRQAIG
                     DYDCKVLMHFPG"
     gene            complement(39229..39597)
                     /locus_tag="TVB59_000298"
     CDS             complement(39229..39597)
                     /locus_tag="TVB59_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009243.1"
                     /translation="MRLWHQDLITRLPRQQLLGQHRECAALRGAGWGRPHATVDYVFA
                     HSLYKLYQYHLLIMQEMQARGYQPDVSWQDKNYRGKSLAAYEDLEEVALTSPIYPEHQ
                     EAYLQECLTNLKEKGIDLDD"
     gene            complement(39606..41816)
                     /gene="recJ"
                     /locus_tag="TVB59_000299"
     CDS             complement(39606..41816)
                     /gene="recJ"
                     /locus_tag="TVB59_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEL1009244.1"
                     /translation="MITSKYQWTIADKEPDAGFFKLAQAKGLSQTAAKLIYDRGVHTE
                     EELTSFLTADLSQLHDPYLLNDMEKAVHRIRQAIEGLERILVYGDYDADGMTAASIVK
                     ETLEMMGAEPLVYLPNRFTDGYGPNQSVYKYFIEQEQVSLIITVDNGVSGHEAVAFAQ
                     AQGVDVIVTDHHSLPAELPDAFAIIHPEHPAAAYPFQKLAGCGVAFKLASALLETIPV
                     DFLDLVAIGTIADMVSLRGENRILVKNGLAVLKETERLGLQELMKLSEVDLAHFDEDV
                     ISFKLAPQLNALGRLDDPNPAIDLLTGFDDEELHELALMISSKNEERKVLVQEIFAQA
                     MAMLDLDKPVQVLAKSGWHPGVLGIVAGRIMEEIGQTVLVLTIDEGLAKGSARSLESI
                     NIFEALNSNRSLFTAFGGHEGAAGMTLPSDRLEELSELLCQYVAAKGHDGQEKNTLLI
                     NGELDLEALSIDSLNKLLLLAPFGMDNKKPVFYLKDFTIKQARTIGQQQSHLKFKVSK
                     GAVEADVLAFGQGHLIQEYQQSQGLELAVSLAINHWRGHTSLQLMLVDARVTGVQLFD
                     IRARTARAPEHIPTAVEDQQAKVVVIDEVPDDIDALKGLFRHREFEAIYFKNHIKRPY
                     YLTGYGSREQFAKLYKTIYQYPEFDLRHKLTLLSDYLKIEKILLVKMIQIFEELGFVV
                     IEDGLMRVKTDAPKRSIADSVIYQQLKELVKFQELMALGSPQEIYQYLMTSEEK"
     gene            complement(41813..42577)
                     /locus_tag="TVB59_000300"
     CDS             complement(41813..42577)
                     /locus_tag="TVB59_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEL1009245.1"
                     /translation="MAQRIILITGASGGLAQAIIRQLPREDYLILLGRSKDRLDSLYQ
                     ARGNKECYEIAIQDPAAIEALVDELYQRHGRIDVLINNAGFGAFKAFDDFSAEEIEAM
                     FRVNSLASIHFARLLGHKMAEQGSGHIMNIVSMAGLIASAKSSIYSATKFAVIGFSNA
                     LRLELAERQVYVTTVNPGPIATSFFEQADPSGQYLASVAGFTLQADTVAKKIIAAIGK
                     KKREINLPISLALAHKCYTLFPTISDYLARKVFNYK"
     gene            complement(42577..43506)
                     /locus_tag="TVB59_000301"
     CDS             complement(42577..43506)
                     /locus_tag="TVB59_000301"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEL1009246.1"
                     /translation="MELQFLGTGAGQPAKHRNVSSLVLKLLDEINEVWMFDCGEGTQR
                     QILETTIKPRKIKKIFITHLHGDHIFGLPGFLSSRAFQASEEQTDLEIYGPVGIKSYV
                     TNSIRISGSKLPYQIHYHEFDDTSMGKILETDKFIVYAERLAHTIFCMGYRVVQKDLE
                     GTLDAEALRAVGVPFGPLFGKVKNGQDIELEDGTKIFAKDFISEPRKGKIITIIGDTR
                     KTSASVRLAKDADVLVHESTYGKGDERMARNHGHSTNMQAAQIARDAGAKRLLLNHVS
                     ARFLGRDCRQMEKDAATIFENVKVVRDLEEVII"
     gene            complement(43521..44159)
                     /locus_tag="TVB59_000302"
     CDS             complement(43521..44159)
                     /locus_tag="TVB59_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEL1009247.1"
                     /translation="MTDYIQLAKTYGGFTSLDTVYLQNCLKGLTDQQKLATITPPPSV
                     INAYFAEMYQKQSPKAATDYYFELSRALKLFTSEPSFDEVKPFVRLNLLGQSYGFVFE
                     NEAQEAIVFAEKEQGQPEESLLLELAQIFPQYVVYVEDGRIKMKSCQFEQGEPEDITP
                     EHALLTTIYRFSNEMTLLKGFNSDELLALSQAFKGKKYYQFAQREFMIYLVH"
     gene            complement(44152..45390)
                     /gene="hflX"
                     /locus_tag="TVB59_000303"
     CDS             complement(44152..45390)
                     /gene="hflX"
                     /locus_tag="TVB59_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002888940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEL1009248.1"
                     /translation="MIETKARQERVILLSVVLQAADHAELSMTELASLAKTAGAEVVD
                     CYLQKRERYDSKTFVGSGKLAEIKEMVAANEIDTVIVNNRLTARQNANLEDALGIKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYMLPRLVGQGVMLSRQAGGIGSRGPGESQ
                     LELNRRSIRHQIADIERQLAAVEKNRQTIRDRRMTSDVFNIGLIGYTNAGKSTIMTIL
                     TGDKQYEADELFATLDATTKQIYLQNQFQATLTDTVGFIQDLPTELVAAFKSTLEESR
                     HVDLLLHVIDASDPNHLEHERVVLDILKDLDMLDIPRLAIYNKMDKTASLTATVFPNV
                     RLSARDKNSRSLLRQLLIDQIRDMFEPFSIKLCQDQAYKCYDLNRLALLEPYSFDKEI
                     EEISGYIAPKNKWRLEEFYD"
     gene            complement(45475..46365)
                     /gene="miaA"
                     /locus_tag="TVB59_000304"
     CDS             complement(45475..46365)
                     /gene="miaA"
                     /locus_tag="TVB59_000304"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEL1009249.1"
                     /translation="MTKEKIIVIVGPTAVGKTALGIALAGAFNGEIISGDSQQVYRHL
                     DIGTAKASAREQALAVHHLIDIREVTESYSAFDFVQDAKRAIEDIVSRGKLPIIVGGT
                     GLYLQSLLEGYHLGGDLDQKELLAYRQQLETLTDTELYQLLASKGIHLDQVNRRRAIR
                     SLELNQFARDLENQEAPYNPLIIGLTDEREVIYERINKRVDLMMASGLLEEARWLFEQ
                     YPAVQASRGIGYKELFPYFQGQASLEEATATLKQQTRRFAKRQLTWFRNRMAVRFDSI
                     SESSYPQAIYDRVERFLKEP"
     gene            46498..46674
                     /locus_tag="TVB59_000305"
     CDS             46498..46674
                     /locus_tag="TVB59_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEL1009250.1"
                     /translation="MAKKHGFAKGLATGVLATAATVAGAVFAVKKTIIDPEEEKAAFV
                     EENRKKAARRRVAR"
     gene            complement(46830..47467)
                     /locus_tag="TVB59_000306"
                     /pseudo
     CDS             complement(46830..47467)
                     /locus_tag="TVB59_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677749.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
     gene            complement(47624..49888)
                     /gene="glgP"
                     /locus_tag="TVB59_000307"
     CDS             complement(47624..49888)
                     /gene="glgP"
                     /locus_tag="TVB59_000307"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEL1009251.1"
                     /translation="MKRFTDYTEMTLGKSLASASNEEIYLSLLSYLKEEASKKAKNTA
                     KRKVYYISAEFLIGKLLSNNLINLGIYKDIKEELAAAGKSIAEVEDVELEPSLGNGGL
                     GRLASCFIDSISSLGINGEGVGLNYHCGLFKQVFRHNEQTAEPNFWIEDDSWLVPTDI
                     SYDVPFKNFTLKSRLDRIDVLGYKRDTKNYLNLFDIEGVDYGLIKDGISFDKTDIAKN
                     LTLFLYPDDSDKNGELLRIYQQYFMVSNAAQLLIDEALERGSNLHDLADYAYVQINDT
                     HPSMVIPELIRLLTQKHGFDFDEAVSVVQKMVGYTNHTILAEALEKWPLDFLNEVVPQ
                     LVTIIEQLDALVRARVSDPAVQIIDETGRVHMAHMDIHFATSVNGVAALHTEILKNSE
                     LKAFYELYPEKFNNKTNGITFRRWLEFANQELADYIKELIGDAYLTDATRLEKLMAFA
                     EDQAVHARLAEIKHHNKVALKRYLKDNKGIELDEHSIIDTQIKRFHEYKRQQMNALYV
                     IHKYLEIKKGNLPKRKITVIFGGKAAPAYIIAQDIIHLILCLSELINNDPEVSPYLNV
                     HLVENYNVTVAEHLIPATDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIA
                     ELAGMDNIYTFGKDSDTIIDLYATGGYVSKDYYDAHPAIKEAVNFIISPELLELGNEE
                     RLDRLYKELISKDWFMTLIDLEEYIAVKEQMLADYDNQDLWLTKVVHNIAKAGFFSSD
                     RTIEQYNQDIWHSY"
     gene            complement(49914..51416)
                     /gene="malQ"
                     /locus_tag="TVB59_000308"
     CDS             complement(49914..51416)
                     /gene="malQ"
                     /locus_tag="TVB59_000308"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEL1009252.1"
                     /translation="MTKRASGILMHISSLPGRFGIGSFGKEAFEFVDFLKETKQTYWQ
                     ILPLTTTSFGDSPYQSFSAIAGNTHFIDLELLAKDGYLQEADYAAVDFGSNPESVDYA
                     QVFQARRPLLEKAVQAFVSTEEGLRQLAEFEATASWLNDFAEFMAIKEHFDHKALQEW
                     DDRAIVKREEAALLHYRKLLAKGITYHKVCQYFFYQQWLALKTYANQNGITIIGDMPI
                     YVSADSVEVWTMPELFKVDADKKPIYIAGVPADGFSEDGQLWGNPIYNWESHEQTGFA
                     WWIHRIKESFKLYDKLRIDHFKGFSDFWEIPGGDVTAKNGHWESAPGIALFKAVREAL
                     GELPIIAENLGYIDEKAEQLLASTGFPGMKILEFGLFDVTSQSFDLPHNYDHNCIVYT
                     GTHDNEVVNGWYEHLSAEQVEFVNHYIHKAAAESITKAMLRTIFATVCDTAILCMQDL
                     LDKSADSRMNMPNTVGGNWQWRMLEDDIKAEHKAYLIHLTELYGRANNHH"
     gene            complement(51623..52645)
                     /locus_tag="TVB59_000309"
     CDS             complement(51623..52645)
                     /locus_tag="TVB59_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1009253.1"
                     /translation="MVTIKDVALKAGVNPSTVSRVLKDNRSISQKTKEKVRRAMSELG
                     YVPNVAAQMLASGLTHNIGLVFPPIITNDRLSDPFFMEILSTITNEAKKHHFTVSIAT
                     GMSVEDLLSQVKLMHLQKRVDGFIILYSEQEDPVRGYLMTNQIPFVIVGAPEGDENKI
                     TYIDNDNQLMAKTAVDHLYQKGHRQILFITDDMEAEVASERYIGYLKGCLKLSLENKP
                     MLLFDRKDPISIEKVIETIRSFKATALIVIGDVLSVRMVQLLSFYDIKVPDDISIITF
                     NNSSYSKLIHPYLTTFDINVENLGRTSFRQLLDIINANEQTLSQKILVPFSLKKRESV
                     RDINAK"
     gene            52892..54145
                     /locus_tag="TVB59_000310"
     CDS             52892..54145
                     /locus_tag="TVB59_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEL1009254.1"
                     /translation="MKSWQKVIVSGASLTLASALLVGCASGSKDKTETASGTDSKTIK
                     LWVPTGAKKSYTDVVAKFEKDSGYKVKVIESEDPKAQEKIKKDASTAADVFSLPHDQL
                     GQLVESGIIQEVPEEYTKEIADTATDQAILGAQYKGKTYAFPFGIESQVLFYNKTKLA
                     ADDVASYDTITSKATFGGTFKQANAYATGPLFMSVGNTLFGESGEDTKGTNWGNEKGV
                     AVLKWISDQASNKGFVNLDANNVMSQFGDGSVASFESGPWDYEAAQKAIGKENLGVAV
                     YPKVTIGGETVQQKAFLGVKLYAVNQAPAKGDTKRIAASYKLASYLTNAESQENQFKT
                     RNIVPANKTVQASEAVQSNELAKTVITMGSSSDYTVVMPKLSQMGTFWTESAAILSDA
                     FNGKIKEGDYLAKLQQFDKDIAATK"
     gene            54445..55806
                     /locus_tag="TVB59_000311"
     CDS             54445..55806
                     /locus_tag="TVB59_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1009255.1"
                     /translation="MTQAGLASQVTVKEALTKGSFDIKLSAIIMGFANFANKQFVKGT
                     LFLLSEVVFFIAFVSQIIPAIGGLITLGTQTQGMTTKTIDGISIQVAVDGDNSMLMLI
                     FGLASLIFCLLFAYIYWCNLKSARHLYMLKQEGAKIPSFKEDFVSLANGRFHMTLMTI
                     PLIGVLLFTVLPLIYMICLAFTNFDHNHLPPKSLFDWVGLSNFGNVLSGRMAGTFFPV
                     FSWTLIWAVFATVTNFFFGIILALLINTKGLKLKKMWRTFFVITIAVPQFISLLIMRN
                     LLNDQGPLNALLSKLGLIHHSLPFLSDPIWAKFSIIFVNMWIGIPFTMLIATGIIMNL
                     PSEQIEAAEIDGASKFQVFKSITFPQILIIMTPNLIQQFIGNINNFNVIYLLTGGGPT
                     NSAYYQAGTTDLLVTWLYKLTVTAADYNLASVIGILIFTVSAIFSLLAYTRTASYKEG
                     AAK"
     gene            55806..56642
                     /locus_tag="TVB59_000312"
     CDS             55806..56642
                     /locus_tag="TVB59_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1009256.1"
                     /translation="MKNKRRFQLGLVYAILTVLSIIWLLPIAWVVLTSFRAEGTAYVD
                     YFLPKHLTLDHYIKLFTNETFPFGRWFVNTFVVAIFTCIISTFITVAMAYSLSRIKFK
                     FRNRFLKLALVLNMFPGFMSMIAIYYILKALGLTQSLTALVLVYSAGAALGFYIAKGF
                     FDTIPYSLDESAMIDGATRMDIFFKITLPLSKPIIVYTALLAFMGPWVDFIFAQVILG
                     DATSRYTVAIGLFSMLQPDTINDWFMAFTAGSVLIAIPITLLFMFMQKYYVEGVTGGS
                     VK"
BASE COUNT        16457 a        13420 c        10674 g        16132 t
ORIGIN      
        1 aaaataaaaa ccctgccaaa aaatctttgg tagggttttt agcaggaaac caaatcaatt
       61 tatcagtttc tctaaatcgc tctaagcaat cattaaacct tgatttacta ggcttccgca
      121 atcaaattgc gatactctat tatttaagag tgatagttgc tccagcttct tcaagcttag
      181 ctttgatttc ttctgcttct gctgctgcaa caccttcttt gatgttagca ggtgcgccgt
      241 caacaagacc tttagcttct ttaagtccaa gacctgtgat ttcacgaact gccttgataa
      301 caccaacttt tttgtcacca gcagatgtca actcaacgtc aaatgaatcc ttagtagctt
      361 cttcagcacc accagcagca gctacagcta caggagcagc tgcagtcaca ccgaattctt
      421 cttcgatagc ttttacaaga tcgttaagct caaggattga agcttcttta atttcagcaa
      481 taatgttttc aatgtttaat gccattgtca tttcctccaa atagttatat taaataatga
      541 tttgtagctc taggctacct ctaaaggcct tacgcagcgc cttctttgct ttctgcaaca
      601 gccttgacag cgtatgcaac gttgcggact ggagcttgaa gtacagaaag aagcatagaa
      661 agcattcctt cgcggtttgg caatgctgca agtgcttgaa tttcctcttt tgaagaaaca
      721 acaccttcga tagcaccacc tttaatctca agtgcttcag cagttttagc aaagtcgttg
      781 atgactttag ctggtgcgat aacatcttca tttgaaaatg ctactgcaga tggtcctacg
      841 aatatatctt ttagctcgtc aagacctgct ttttcagctg cacgagtcaa gattgagttt
      901 ttgataacct tgaactcaac gccactttca cgaagtgaac gacgaagaac agtatcttga
      961 tcaactgtaa gaccacgtga atctacaaca acgatactta cagctgcttt cattttctca
     1021 gcgataagct caacttgttc agctttttta gcgataattg cttcactcat tagttttacc
     1081 tccgttttta tttttgggct aggcacaaaa aaatcgcacc taaacctaga cacgaaagta
     1141 caaatacgtt atcttcaata atgacgtttt gtgcctcggc aggaatatta tgagcacgct
     1201 cccctgctgt cttaggtcag ttttattcaa aaccatagtt agtatagcct ttttaaatga
     1261 ctttgtcaac ctatttttta gaaaatctta aataaaaaag gaaagctctt ggctttccgc
     1321 taaatagatc tgattagtgg ctcaaaagcg cctcctaact taagcctaat gataagcaac
     1381 ttgtgacgat tgattgctat aacttagccc gatcaagctc cacagtatca tctcataaat
     1441 aaagaagaac aaggcaaagc aatgcccaaa aaaggcctct ggcaaaatcc aaatgacagg
     1501 atctgtcagc ggatcaaaca accagcttga atctcctaca aagagaattt gatgaaaaag
     1561 ggtaaagaac tgatcaaagc caatcattaa agcaaagcaa gcaatcacaa ttggcaataa
     1621 ggctgctgct attagccctc ttcgaagcag cataaccctt ccttttttga tgctctgata
     1681 aaaatagata atggttggca acataagcag gctaaagatc agctgtgtta tatgaaacag
     1741 cattttcaca tctgtaaaat gctttagacc agctcttgat gctgaaaagc tggctagctt
     1801 tagctcacga acaaaaggat tggttaagta agtcagcaat atattatagt tgtggagaat
     1861 agactttttg cacatcaaaa ctgcctgctc tagttgcaaa taatcaacct caatcggata
     1921 aagcagccaa gataaataga tagttatcaa aactgccagt gctagtagcc aaagccaact
     1981 ggcaatgaac ttgccttttt caatcataat agctcccact catctaagct agccaagaca
     2041 tgatcaggct taattggaag gcttggaacc tcttttgcct ttgtaaagcc ggttgttact
     2101 agaatagttg ccatatcatt ttgaattcct gccatgatat ctgtcaggta attgtctcca
     2161 accatagcca cctcagaacg tggtaccttt aagatctcta gggctttatt catgataatc
     2221 gcatttggct ttcctataaa tactggcttc actctagttg ctgcctcaag gagcgcattt
     2281 aaagcgccag cacctggcat tagcccacgc tctgttggaa tatttaagtc aggattggtc
     2341 ccaataaaca aggctccttt ttgaatggca agtgttgcaa ttgataacat ttcataggta
     2401 acctcagtat ctaagccaac aacaacatag gctggatttt ctgtatcctc ggtatagcct
     2461 gcctctgcaa tggcagactt taagccagtc tcgccaatca cataggctgt tttgcctcga
     2521 ttcatatcat tcatgtaatc aacggttgcc attgtagcgg tgtaaatggt ttcaagacct
     2581 gtatgaacgt taaattgatt ggctagcatt tcctgaacca tttcaggtgt tcttgtggtg
     2641 ttgttggtaa ctaagagata agggatacct ttttcctgta aacgcttgat aaagcgctca
     2701 ccagccggga tacgattttt cccttgatag atggttccat ctaaatcaat taaataagct
     2761 ttatagggca ctaatttgtc tcactttctt tagtcgttat aggctgccat ttgataatgg
     2821 cctgcgcatt aagctggcct gatgacctga tctcatggta ggaggtcaaa tgctctagat
     2881 gatagcctga ggttatttga gtgctgggcc tcacctcttt gatataggtc aaggtaaggt
     2941 ggcaaggtct gtggtgtaat aaaaattcat atcccaaaac gtcatacatc caatccaaat
     3001 acttactatt attggcatga ccattcatat caatgtcaaa ataacgaacc tgataagctt
     3061 gaaccatagg atcctgaagc tcatctattt tgataggacg cttgattttc ttaacaaagt
     3121 cagcctgata aggcaccacc aaatcatctg gtatcgcagc tgccttacgt gtttgaggat
     3181 ttagcagggc aaaatgagat aaaatggtca tgatggcatg acctgcctga tcataaatgt
     3241 gaaattgccg gtaacaaaat aatttattgt aagaaatagc ttgcgtttca atggttactg
     3301 tttccccaaa ccttggcata cgatcaatcg ttacatcata atccgtaaca acccaaatca
     3361 agccatattg ctgaagtaac acctcattgc ctcgtccaat ttcagctgat tgtcttgctg
     3421 ataccattaa gcaatgtgct aataaaaggg gcagcttgac atcagcctta acatcacaaa
     3481 aatcaaaaga cagcttaagg ctttcgctat accttaatcc cataacacac ctcctaatct
     3541 aagatgaatt tttcagcgac agaatcacct aaaaagaggc cttttttggt cattctgata
     3601 aagtccttgt cctctaccaa aagcccctga ttctgaagct ctctcacaac aggaccatag
     3661 cgtgactcaa atgataggcc aaatttttct tgaaaccgac tgactgatac tcctgatttt
     3721 tttcgcagac caagaaaaag ctcctcctcc atcatctcct ccttggtgag cacttcctca
     3781 cttaacctag catttccatc tgctactgcc tttaggtaat gctgaatagg aacccggttg
     3841 cggtaacgaa tcccatcaag atagccagaa gcccctgcgc cacagccaaa atactcatca
     3901 ttattccaat acatcagatt gtgcctgctt tcaaagccag gcttagtaaa attagaaatt
     3961 tcgtaatgct caaagccact ggcttccatt tcagaaataa tatactcaaa catctcagct
     4021 tccaaatcct cagtgggcaa atggagcttg ccacgacgca ttttgttcat aaaaacagtg
     4081 tgatgctcta ggataaggct atacaggcta aggtgaggaa tatctaaagc aagtgcctta
     4141 gccacatttt ccttgacctg ctgcatggtc tgtccaggca aagcataaat gagatcgata
     4201 gacatatttt gaaagcctgc ctccttaaga ctagcaatgg tcgtataaat ctgagcctca
     4261 gtatgactgc gtccaatctg ctttaattgc ttgtcattaa aagtttgaac gcctagggaa
     4321 atccgattga cagccgattg ccttaatact gcaatcttat cctcagtcaa atcacctgga
     4381 ttggcctcga tggtaaattc ttcaagctgg tctagctgta ggtgctgctg caaatggctc
     4441 agcaaataat caagctgatt ggctgttatg gctgttggtg ttccaccgcc aatataaagt
     4501 gtcttcaagg agctgatctg ataggattca aattccttaa tcagtgcctc taggtaggca
     4561 tcgacaggct gatttttgat aaatacctta gaaaaatcac aatagtagca aatttgtgtg
     4621 caaaaaggaa tatgcacata ggctgaggtt ggtttttttg acatggtaat attatatcat
     4681 tttagctcag aaattcatgc caagtgatta gctttttgac atgtactaac ctaaggctgc
     4741 ttctttttct ccattctcac aaaggaatga ctactcccat tagcatactg ctcaaagctt
     4801 gaggttggct gatagcccat tttttggtag aggctttgtg cgcctttatt aaagctagcg
     4861 acatttaaaa cataggtttc ttgcggataa gtagtgctag caaaggcttc aatgctgccc
     4921 aaaaaagaaa caccatcttc ctgaccagta gtatcagggg ccataccaag accaatctca
     4981 agctctgatt cctgttcaaa aaagctggca aagccaaaaa gaacaccatt gcgaagcact
     5041 tgaaagtaat gctctccacg cgccttgggt gacaatattg actgatagtc ctcaggatca
     5101 gcagtcatgc tatagcactc ataagctggg ctatagatcc agtcatgcgc aatgatttca
     5161 gcactatgct gtgtcatcgg catcaggtaa aaagaagact cagacaataa gcgatgaaag
     5221 gtcttgttga tatgctttat gcgacgccgc tgcacatcag gctgatctgt ttgataaatg
     5281 taattagcat agccctcctg atattctgga atcattgtca aatacagctt ttgggtcaac
     5341 tcatcaagct gactagcaat cctatccact ctatgcttta tcatattacc tccaattcta
     5401 atgctgcttg atagcataaa aagtgccgaa gcaacgacac tttttctaga ttaatcaagg
     5461 ccaatttccg cacgaacaac cgctgcaatg gtatcaacat aatagtcaac ttcttcattg
     5521 cttggtgcct ctgccatcac acgcaacaat ggctctgtgc cgctaggcct taccaaaatg
     5581 cgaccattac cagccatttc tccttccatc tgagcaataa cctcagcaat agcaggcact
     5641 tccatagcac gctccttcat gctgttgtca acacgaatat taacaagctt ttgtgggtaa
     5701 atagtgacct cactggccaa ttcggagaga gttttacctg tctccttcat gattttggtg
     5761 agctgaacag ctgtcagttg accatcacca gttgtattgt aatccatgat aatgacatgc
     5821 cctgattgct caccaccaag attgtagccg aactgacgca tctcctcaac aacgtaacga
     5881 tcaccaacag ctgttacctt cttatgaatg ccacagctat ctaatgcctt gtgaaaacca
     5941 aggttagaca tcactgttgt cacaatcgta tttttagcta gcaagccctt ctcagaaaga
     6001 tacttgccta tgataaacat gatcttgtcg ccatcaacaa tagcaccatt ttcatcaaca
     6061 gcaattaaac gatcactatc gccatcaaaa gccaatccaa tatcagaggc tgtttctgtc
     6121 accaagtcct gaagcttttc agggtgtgta gagccgatac catcattaat gtttaatcca
     6181 tttggattct caccaataac tgtaatgtct gcatttaaat ctaaaaagac attacgagct
     6241 gaaacagaag ctgcaccgtt agcagtatca agagctatct ttaaaccgtc taaatctgct
     6301 ccagtagtaa ccaagaatct ctcgtacttg cgcaagcctt ctggataatc aaccaaggct
     6361 cctaagccct ccgcacttgg acgtggtagg aggtcctctt tggcatctaa gagcgcttcg
     6421 atttctagct cttgctcatc agccaattta aagccatcac tcccaaaaaa cttaatgcca
     6481 ttgtcaagag caggattgtg actagctgaa atcatgacac cagcactagc cttttctgta
     6541 cggaccaaat aggacacacc aggagttgca agaacaccaa gcttatagac ctctatccca
     6601 acagaaagca agccagcaat cagggctgcc tctagcattt caccagagat acgggtgtca
     6661 cgagcgacaa aaactctagg cctttcagtc tcatgctgac ttagcacata accaccgaac
     6721 cgaccaagct taaaagcaag ctctggggtc aactctacat tagcctcgcc tcgaacacca
     6781 tccgttccaa aatattttcc cataatttat atcagctaaa cgcttcctcc attccatttt
     6841 cctagctatt atgctttatt ttttaattgt tgtcaactga acggttacta ccgaaggctc
     6901 tatagaaacc tgatttgaaa ccaagctgac cgttttgctc gtgtttttgg tgacgtcaga
     6961 aatattgacc tctgccacca cctcatcaat agtttcaagg acctcccgac taccagaaat
     7021 aacagcggtc tgcttggaga gcttatactg gatatctgac agactgtcat ccattagtcc
     7081 aactgcctcg actcgaatag gaactgattt ggtgattttt ttgacagaaa ctgacaaatt
     7141 agccttggct ggatcgatcg cactagctaa aatggtacca tcggcagcta ctgcctgcag
     7201 ggttactcgg ctgctataat tagcatctag cacctgatca tcaggtaatt tagcgacaac
     7261 atgatctatc aaggcaatag tagactcatc acttgtgacc tcaaccttgt caatacctgt
     7321 ttcaattttg ctaatctcat agcccttagc cagctgctta ctatcgacgc tgccacgcac
     7381 cggaaaggtc tttgttttct tatttccaat cgttaccgaa atcttatcag gagaaacagt
     7441 tgctgtcaca ccagtaggta gattgataac ctttagggtc accgttgcag tacctggctt
     7501 actctttgtt agatcagcta cgatcttaaa gcttctagtg tcactgttta cctctgaatc
     7561 cagctttatg cggttggtag aggtcagata aacctctgca ccgtaagaat agccgctgat
     7621 gaagtactga tcactatcat acttgatatc aataggaacg tcctttaagc tatgggtgta
     7681 ggtttcaata gggctataaa tttgagaatt agaatgatta tgactgctag aagcagcggt
     7741 caaaaaaaga ataatcgcaa aaaagattga cactaagccc agcccaagac gactatttaa
     7801 aaacctcttc atttagcttt gcctcctaag atttttttat accaaggtaa tgtcgcaccg
     7861 ggctcattca tcaaatgagt cttgagaacc gcctcaagct cttctgttga aaggtcgtgt
     7921 aaaaattgac ccttacgagc gatagagaca gctcctgtct cctcagaaac aattatcgtt
     7981 acagcatcag aattttctga aagtccaatt gctgctctgt gacgtgttcc aaattctttg
     8041 gaaatcgaca ttgattcaga caaggggaga taagcacagg ctgcagcaat tttattgtta
     8101 gccacaatga ccgcaccatc atgcagcggt gtgtttggga taaagatatt gatcaatagc
     8161 tgactagaaa tatcagcatt taggggaatt cctgttgcga tatattcctg caaggtctgc
     8221 gtttgctcaa tagcaatcag agcaccaatc ttccgcggtc ccatataagc aactgatttt
     8281 aagagcgcat caaccagcat ctcctcatca ctcaagcttt gcttttgcaa aaatacctgt
     8341 gttgatcggc caaatttttc aagccccgct cgaatttccg gagcaaaaat caccacacct
     8401 gcaatcactc cataggtgat gacctgattc atcagatagg ttatagtcgt aaaccctatc
     8461 cactcggcaa tcacacgaat gatgataaag aatataaccc cttgtaccaa ggacatgatc
     8521 ttagttcctg ccaaggattt aataaaacgg taaatcaaat aggctactat taaaatatcc
     8581 agcaaatgaa ccaccaacat caaggggtca tcaatcaggc ttagtaaaaa ttttgtgtca
     8641 atacttgata aattactcat acaattctca tttctatgtc agatagatac ctctaacatt
     8701 atatcacgtt tcaagatgtt ttccctatct aaaatttaag aacttatgtt aaaatattaa
     8761 catgaaacta aagacactac tcgctatagc agccggaagg actgcgcagc tcattttaaa
     8821 taaaatcgga agaggctcaa cctaccccgg acgattggcc ttgatgtggg ataaggatat
     8881 tttagacaca cttgccaagg actatgagat tgttgttgtg acagggacaa atgggaaaac
     8941 cttaaccaca gctctaactg ttggtatcct aaaagaagcc tttggtgagg ttttgactaa
     9001 tccaagtggc gccaacatga tgacagggat tacctctgcc tttttatctg ctaaaagaaa
     9061 aaaaacaggc aagcctattg ccgtcttaga gattgatgag gcaagccttg caagggtaac
     9121 aacatacatt aagccaagtc tttttgttta cactaatatc tttcgagacc agatggatcg
     9181 ctacggtgag atttacacca cctatcagat gattgttgat ggtgctagtc aagcgccgaa
     9241 ggcaaccatt ctagctaacg gtgatagccc tatctttgcc tcaaaggacc tggttaatcc
     9301 tgttaaatat tatggctttg acacacctaa gcatgagcca cgcctagctc actacaacac
     9361 tgaaggcatt ttgtgcccaa aatgtgaaca gattctccgt tatcgtctca acacctatgc
     9421 taatctagga gactatacct gcttaaattg tgatttccaa aggcctaagt tggattacaa
     9481 gctaacgcaa ttaaccagca ttacccatca tagctcagcc tttgtgattg acgatcagac
     9541 ttatcgcata aatgttggag gactctataa catctataat gccctcgcag ctgttgctgt
     9601 tgctgagttt tttggcattt ctgctgatca gattaaggct ggcttcaata aaagcaaggc
     9661 tgtttttggt cgtcaggaaa ccttctccat caacggtaaa gcctgtacgc tggttctcat
     9721 taaaaaccct gtgggtgcta gtcaggcact agaaatgctg cgcctagccg attatccctt
     9781 tagcctatct gtgcttttaa atgctgatta tgctgacggt attgacacaa gctggatttg
     9841 ggatgctgat tttgaattga ttaatcaaat ggacattact gagatcaacg ccggtggggt
     9901 tcggcattct gaaattgcaa gacgcttacg agtgacaggc tttgatgagg ctaaaatcac
     9961 atcattcgat aagcttgaag gtatcatgca agccattgaa aaccaagagg ctgagcatgc
    10021 ctatatccta gcgacctata ctgctatgct agcatttcgt gagctgcttg ccagccgcca
    10081 cattgtcgaa aaggagatga tctaatgacc tatacctcgc tacaatctcc ggaaaatcgc
    10141 gattatcaat acgaccttca tattgctcac ctttatggta atttgatgaa tacctatggc
    10201 gataacggca atgtcttgat gttgaagtat gtcgctgaaa agctaggcgc taaggttaga
    10261 gttgatattg tatccattgg ggataccttt gaccaagatg attatgacat tgttttcttt
    10321 ggtggtggtc aagattatga gcaagccatt gttgctagag atttgccatc aaaaaaagag
    10381 gccttagcag cctatattca ccaaaataag gtactccttg ccatttgtgg tggctttcag
    10441 ctgctgggac agtactatat tcaagccaat ggccttaaaa tcaatggcat tggggttatg
    10501 ggacattata ccttaaacca agataataac cgctttatcg gaggcattaa aattcacaat
    10561 gatgactttg acgaaaccta ctatggcttt gaaaatcatc aaggacggac ctttttatct
    10621 gacgatgaaa agcctcttgg acgtgtcatt tatggaaatg gtaataataa agaggaccaa
    10681 actgagggcg tccactataa aaacgtttac ggcagctact ttcatggacc aatcctttcg
    10741 cgtaatgtca gcctggccta tcgcctagtc acaactgctc tcaaagaaaa atatggctcg
    10801 actgtttcct tagcggccta tgataagatc ttacagcatg agacctcaga ggaatacgct
    10861 gatgttaaaa gcaaggctag ctttgacagt taagtccttc tcatagcctg attaaaccac
    10921 aacagacatg caaaacagtt attcccgaat gaaaatatag atttaaatag acaccctcaa
    10981 tgtttttcct atcataaaat ccataaaaga taagacatat tcttgcaata actgaacatt
    11041 gaaagacaga aagctttctg tccttactaa acatctttca tgcgtctgtc gtgctgatca
    11101 agcgagataa ccccaaaaaa gtgctagcac agtaacaaaa tggctatgac catatgtctg
    11161 tgcagctcta ctgtcactgc atagacaggc tagaggggac gccctacttg gttcagcgat
    11221 ctaggggtag gtctagcttg tttgtgctga gtctgtttcg gtagcaaaga ttgaatcctg
    11281 ctataagata ctctcaaaaa gattaaccca aaagccttgc aacacattta acgtttttag
    11341 ggataagtac cgatatgcag acacatagca ggagatctat gtgtctggta ccaaaggaca
    11401 caaaaaacta aagtaacaca ctaaaagcca catgataccc atttgatagg gggcgtcatg
    11461 tggctttttt ctatctcact gttcattaca aaaagccaaa ccagcttctt tttgcattag
    11521 gcaacaatgg cctttgccac ctcttctact gtcatacgtg agaaatattg tgttgtatca
    11581 atggtttgaa gacgctcaag cacatcagca tactcgtatt tgcaaccaat gagtaggctt
    11641 tcaatatcct gcacgtcctt aataccaaag aaatcaccgt agatcttaag attcttaata
    11701 acagaatttt caacattagc aaaggttgag attttaccgg cagggtagcg aacattacgt
    11761 tcaatcgtgt attcaggtgc ctttccatag gtccaatccc agctcccaaa ttgctcctca
    11821 gccgattgtt gaatcttagc cagctcgtcc tctgacaaga cgtattctgt catgtctgga
    11881 taggtctcct tcattttaac caaaatcttg tctgaaaatg cttctacgct gattttttct
    11941 ggcagctcat ttaaaatatt ggtcacgcgg gctcgtacag atttgactcc tttggactca
    12001 atcttatcct tactgacctt gagcgcatca ccaagaacag tcatatccac atcaaacaag
    12061 agacagccat gatgcatcat acgtccctta taataggctt gagcattgcc acagattttc
    12121 ttgccatcaa tttcaatgtc attgcgacct gtaaaattag ccttaactcc taaatcagcc
    12181 aaggtctcaa taactggctg tgagaaggtt ttaaaatcaa aggctccttc tgttgtttta
    12241 ttggaaataa tcgtgtagtt aaggttattg agatcatggt aaactgcacc accgccagac
    12301 aagcgacgaa ccacatgaat accatgctgt tcgatgtact ccttgttgat ttcctgaatg
    12361 gtattttgat gcttaccaat aataatagcc ggctcattga tccagaggat aaacaattca
    12421 tcctcatcaa ccaattctct aaaggcataa gcctctagag caatgttaaa ggcagggttg
    12481 tggctcttat taacaatgta tttcatttct atctcctata gcgataatcg ttatcatatt
    12541 ctattcttta ttctaatgga aactcttaca aaagacaagc taaaagaggc tagcaaaagc
    12601 aagggaacta gtaaatgctt cctcaatcaa gaaccatctg caagctagca gtaaagcttg
    12661 atctaactta aagagccttc cttgtatcaa cgaaagagct gagaaatctt tttcccagcc
    12721 cttttttatc gcagctatat agctagctta ttttttacgt tttggtgggt tatgaatggc
    12781 ttcgccaagc acatctgcaa aggcttcgta catcacctct gagaaggttg ggtgtccatg
    12841 aattgacaat agcaattcat caactgttag ctcagcctcc atgattgtgg ctgcttcatt
    12901 gatcatttca gcggctgctg gaccaatgat gtgaacacca agtatttcat ggtatttagc
    12961 atctgcaata acctttacaa agccatgagc ctcgtttgac gcaatagcac gaccatttcc
    13021 tgtaaagcta tttttaccaa taagaacatc gccatattgc tcacgagcct gctcttcagt
    13081 taaaccaacc atagcgacct cagggtgagt atagaccgcc gctggagtgt attttaggtt
    13141 agccttacgt gttgtgctgc catgcatggc attctcagca gccacctcac ccatacggta
    13201 agcagcgtgg gcaagcattt tagtgccgtt aacatcaccc ggtgcataaa tgcctgggat
    13261 tgacgtttct tggtagtcat taaccttaat gcggttacgg tccatttcaa ggttgaggtt
    13321 ttcaagacca ttcatctgtg gcacacgtcc aatagatagc aaggcctttt cagcaacaac
    13381 ctcttcgcca ttattaagct tcaaggtcaa ctggttgttg gcttcaacaa tctcagagac
    13441 accaactgag gtctttattg tcatgccttt cttagaaagg attttttgaa gctccagtga
    13501 aacctccttg tccatggcag gaataatgcg gtcagccatt tcaataactg taacctctac
    13561 accgtaagag gcccaaacaa gaccaagctc aataccaaca acaccaccgc ccataacagc
    13621 aagtgatttc ggcatttcac gcaaatcaag aatatcatca gatgtcaaga caagcttaga
    13681 atcaatccct ggaatattga tgcgtgagac cttagagcct gtcgcaagaa taatattgcg
    13741 ccctttaatg gtttgcacac caatggtaac cgttttatca ggatttacct gaccaaggcc
    13801 attaaagatg gttaccttgt tggctttaag aagcccttga accccacctg ttagcgtctt
    13861 aacaaccgta tttttaaagt caactgtctt atccatgtca atagtatagt tggttgaagc
    13921 aaggttaatc ccgcgtcctg ctgcaatctt gatgccatca aggatttcag catttttgag
    13981 gtaggttttt gttgggatac agccaacgtt taagcaggta ccgccaaatt cagatttttc
    14041 aacgatagca atcttgccgc ccagctgagc accacgaata gcagcgtagt aacccgcagg
    14101 accgccaccg acaacaatga tgtcatattc atcagcagca agctctgcct ttggtgctga
    14161 tggcgctgat ccttgatccg gtgcctttgg cacctcaaga ccagccgcct gtaaatcctc
    14221 ggttgtacgc gcaacattga catcagccgc tgctgggctt gatacatcga tagcttcacc
    14281 cgcagctcca atgtagccga taacttcggt tacagggact gtctcacctg cctggcgaat
    14341 gatttttaaa agcacacctg agtcttctgc ttctaattcc atattggtct tgtctgacat
    14401 gatttccaga agaatgtcac cctcgctgac agtgtcaccc tcctgctttt tccactcgat
    14461 gatctcgcct tcttgcatgt caacaccgag ctttggcata ataatttcaa cagccataat
    14521 gatattgtaa ggaacgttca aatgcaatca gatgccttaa caatcagcac tggctaacat
    14581 aagcctgcta aaagccctgc atttagctca tagctagtga ctacgagctc gttccagatc
    14641 ctttctatag ttttaaagaa ttatcttttc gttactttgt ttctgaaata tgctctcttt
    14701 gcatcgcagg ccataaggcc tgtcatcaga ttagcagttc aaatggattt tccatcaatt
    14761 ttttgagatc aaccatgaat ttagcaccat tcatgccgtc caccagacgg tggtcaattg
    14821 tcagacacat tgccatgatt ggacgtgcaa caatctcacc atcgaccact gttggggttg
    14881 gaatggttgc cccaatacct agaatagctg aattaggctg attgataatt ggattgaagg
    14941 ttttggtgcc aaacataccc agatttgtga tggagaaggt tgagcctgac atttcggtag
    15001 cctttagctt gcctccttga gcctttttga taacgtcctt agaagcaagg acaaactctg
    15061 agagactcat cttatctgca ccatgaacaa ctggcacaac tagcccatca tcaagtccta
    15121 cagcaatacc aaggttgaca aagcgatgaa gctcaatatc attagcatca ttaatcaatg
    15181 acgcattcat gtattcgtgc tctggcttca tcaaggtctt aacaacggct aaaccaatca
    15241 agtcagtaaa gctaaccttt agccctgttt tagccatgat tgggtcaatc agcttcttgc
    15301 gcaaggcaat catttcggtc atgtcaatgt cataattaag cgtaaaggtt ggtgctgtaa
    15361 ggtaggaatg tgtcataccc tttgaaatag ccttacgcat agcagacatc ttcttaattt
    15421 caacaccctc tggaagctcc ttagcaggct tttcttcagc aatagatgct ttttccacag
    15481 caggtgctgc tgcgccaagc acagccaaaa tgtcctcctt ggtaatcttg ccaccaatac
    15541 ctgttccgac caccgctgca aggtcaactc ccttgtcggc agctatctta cgagcaagtg
    15601 gcgttgcctt aggctgagct cctttgaagc cttcaacgtc ttctttgtgg atacggccct
    15661 ttggtcctgt tcctggcact tggttaagct caattcccat ttctgaagct gctttacgag
    15721 ctgctggcgt tgcgcgtacc ttttctccga aggctggagc attggcaact gatgctacct
    15781 gaggcgctgt tgaggctgct tctttcggta cagttgttgt attagcttct gctgatgttg
    15841 gtactggaat ttcagttgtt ttctcacttg aagcagtact attatcaaca gattcacctg
    15901 cagcaccaat atagccgata acctcagtga cagggactgt ttcacctgcc tggcgagtga
    15961 tttttagaag cacacctgaa tcctctgctt caagctccat atttgtcttg tctgacatga
    16021 tttcaagaag aatgtcaccc tcgctaacag tgtcaccctc ctgctttttc cactcgatga
    16081 tctcgccttc ttgcatgtca acaccgagct ttggcataat aatttcgaca gccatatatt
    16141 tcctttcatt taatcccgca gcccatgatc ttaagaccag atacagctgc tgaaaaaagg
    16201 gatactgttt tatcagcctg atgaagaaag cctctaagct aagacttcct ttgccatgct
    16261 aatttccctt gttgaccatt tttacaatag cagccttgat tttagcaaca tctggtaaga
    16321 tagcttgctc aagaacacgt gcataaggta ctggtacgtc ctcactagca agacgcacaa
    16381 ttgggtgatc aaggtaatca aaggcttcac tttcagtgac cattgctgca atctcaccga
    16441 taaagccacc agtcttatag gcatcattaa caagcataag cttccctgtc ttcttaacag
    16501 aattaataat taattcctta tctagtggga taagggtacg tggatcaaca acctccacat
    16561 taataccatc agctgcaagc tcttcggctg cctgaaggac acgctctagc atacgcccat
    16621 aggaaacaat ggttacatca gtcccttcac gcttgatatc ccccttgcca agtgggatat
    16681 aaaaatctgg atcctgattg acctcttctt ttttaccgta caaggcctta ggctccatga
    16741 aaataacaat attgttatca cgaatagctg actttaaaag tccctttgct tcgttagcag
    16801 ttccaggtgc aaccaccttg atcccaggaa tatgcgtcaa ccaagcctca agagattgcg
    16861 aatgctgagc tgcagatcca attcctgagc cagaagcaac acgaaaagtt gctggcgtga
    16921 tcaagccacc accaaacatg tagttgtttt ttgccccatt attaacaatt gcatcaagtg
    16981 caatggtaat aaagtccata aaagtaaggt caacaatcgg acgaagccct gtaattgctg
    17041 aaccaatcgc tgcacctgca atagcagcct ctgaaatcgg cgtatccttg acacgtttgg
    17101 caccaaattc ctcaatcatg ccaacagaag taccaaagtc tcctccgtaa acacctacgt
    17161 cctcacccat aaggtaaatc gtgtcatctt tgcgcatctc ctctgtcatg gcaagattga
    17221 tagcctcacg caaagccatt aattttgttt ctgtcattat tatctcctaa tgtttacaaa
    17281 atagaattgt caatgttact gtgaatagat ttttgctcga tgtgctagca gatcagctag
    17341 tctacccaaa cgtcctcaaa ggctacagaa atgtctggat ctggactatt ttgtgcaaac
    17401 tcataagcgt catcaatttc ttgcttgacc tgtgcttgaa gcgcatctaa ttcttcatct
    17461 gtagcaatgc cttcacctgt taggtaagcg cgatacttaa gcattgggtc cttttccttc
    17521 cactcatcaa cctcttcttt ggtgcggtat ttgccggcat cagcagttga atgaccaaac
    17581 caacggtaag actcaacctc aacaacagca ggaccattgc caccgcgaac atgctcaaca
    17641 gccttactca tggtttcata aactgccatc acatcgttgc cgtcctcaca ataaaagcct
    17701 ggaataccat aagcctcagc acgcgtgtag aggtgaggtg tatttgtggc attgttaatg
    17761 ctcatggaaa tcccatagcg gttgttaatg ataaagaaaa tcacaggaag cttccaagtt
    17821 gctgccatat tgacagactc atggaaggag ccctcatttg ttgcgccatc tccagaaaag
    17881 gccacaacga tattgttggt ccccttgtat tgctgtgtca aggcagcacc taccgcaagg
    17941 gcatagccac ctccaacgat accatttgtt ccatagtttc ctttttcaaa atcagccaag
    18001 tgcattgagc cgccgcgtcc ctttgacaca cctgttacct taccggctag ctcagccatc
    18061 attttattga ggtccatatc tttagcaata gattgcccat gcccgcggtg gtttgaaaaa
    18121 ataatatcat cataggtcaa atgtgccaca gcgccaacgt ttgctgcctc ctcaccaact
    18181 gagaagtgtg tcatgccctg cacaaatcca cgacggacaa gcttattaat acgtgaatca
    18241 aattcacgaa tacgctccat tttaaggaac atatctaaat gttgttcttt agaaactgtt
    18301 accatttcgg cctccatatt atcatattac ttcctaatca taaaactttt cttcacaatt
    18361 tgcaaggatt ttaatcgctt tctttgtgac tataaaagct tttttaagac gttttagttt
    18421 gtggtttcac aagctagatt gttatagcat ctgttacatt tatatataac agattgaaaa
    18481 atgagtcagt gtttattcag ggaggtcaag cacctattga ctttgatagt cagaaatatc
    18541 atcactcttt aagaggaaaa taggctctaa atgacctgtt tcttctagca caatcatgat
    18601 cacctaccaa acgaacgctt tgcttgcctc gctccgatag aggcgaaatg aactaaaaat
    18661 cgcataacta aaaatgcctg attttacctg aaaatcagac atttaaaagc tttaagacat
    18721 tagactcagg ctctaattat aatcctctaa gaaaagcctg ctaccttgca ctacccaaga
    18781 atagcaaggc aatttcatta tctcaccagg ctactccagc tgtcctgcaa tgtcctccca
    18841 ctccagcagc aaggtctcct gtttctgatt aagctgatcc aactcttttt gccagtctat
    18901 cagttgagtc gtatcatttg atactagcat ttgagcttct atagccttag cctgtgcttc
    18961 tagcccttct aaggtctgct caatctcctc aaagcgcctt gttaagcgac ggtattcctt
    19021 ttggctggcc ttttgaagct gataatcagt tacagcagct tctgctacat cagtctctac
    19081 tacgtgatct gcagcagcta gacgggctaa ttcctcccgc tctgcctttt tttctacata
    19141 atagtcgtag tcccccagat agagtgttga gcctgcttca gttatttcta aaaccttagt
    19201 ggccactcgg ttgataaaat acctgtcatg actaacaaac aacaaggtcc catcaaagtc
    19261 aatcaaggca ttttctagaa cctctttgct atcaatatcc aggtggttgg ttggctcatc
    19321 tagaatcaga aaattgtcct ttttcataga taattttgtt aagagcagcc gagccttttc
    19381 gcccccagat agcatggcca cagacttttt gacgtcctca ccagaaaaga gaaaggcacc
    19441 taagcggctg cggatctcaa gctcagctgt cgttgggaaa tcacgccaaa gctcctccaa
    19501 tacagaatta ctaccagtca gatgagattg cgtttggtca taatagcctg tttcaacatt
    19561 agtcccataa tggcatgtcc ctttaatcaa aggaatctct ccaataatgg atttgagtag
    19621 ggttgacttg ccaataccat ttggcccaac aatagcgatt gcatctaacc tacggacatc
    19681 tagatgaatt ggctcagcta aaatatggtc attgtagcca atagcggcgt ctgtcacctg
    19741 caaaacaaca tttcctgagg gcttatcaat ctgaaaagtc atactagctg atttgcgaga
    19801 gctacttggc ttgtctaagc gttctagctt ttctagctgc ttgcgtcttg cctgagcacg
    19861 cttggtcgtt gacgctcgaa caatgttttt ttggacaaaa tcctctagct tagcaatctc
    19921 tttttgctgc ttgtcataat gcttctcttc tgctgcaagc ttttcagcct ttaaatcaat
    19981 aaagcgtgag taattaccaa catagcggtc taagctattt ttagtcagat caagtgtgat
    20041 ggttgcgacc ttatccaaga aatagcggtc atgactgaca atgatcaagg ctccctgata
    20101 atttaccaga taatgctcca gccaggcaat ggtttcaata tctaaatggt tggtcggctc
    20161 atcaagcacc aatagctctg gcttttctag tagcattttt gccagggcca aacgggtatt
    20221 ttgcccacca gaaagctctg agattttcat ttcccacatg ctttcgtcaa acttaaagcc
    20281 atttaaaata gctcgaatat ctgactcata ggtgaagcca tttcgcaagc gaaagctttc
    20341 tgacagccgg tcatagtctg acatgagctg gtccagagct tgccctgatc gactggccat
    20401 atcagcctcc atttgcctta gtcgctgctc atcaaccctc aattcagcaa atacctttag
    20461 catttcctga taaatggtct tgtcagactc aaatcggcta ttttgtgcca aataagatag
    20521 ggttaagtcc ctttttcgac taacctcacc gctagttggc tcttcttctc caactaaaat
    20581 cttaagaagg gttgatttgc cagcaccatt tggcccaacc aaggcaatgc gatcacgttc
    20641 accaacctgc agcgataggt tttgaaaaag cacctctcct gaaaaagagc gctcaatgtt
    20701 atttccttgt aatataatca tacccttatt gtagcaaaaa aatgcccttt tggggggcac
    20761 ttttagttat ttttacaggt aagataagac tcatcaacaa gctaaagaca taagccttag
    20821 gctaacatcg cttatcaccc ttagtggtat ttatctgatg agacaaactg ctgcttgaaa
    20881 aaccagtggg ttgacctgtt agcgtatcca acaatcgcac cacctgctca gttatgcttg
    20941 aaatgctatt agccagtgag gaatcactat ggttcgaata ataaatcaaa ccaaaaataa
    21001 gcaataccaa tactattagg gtctgcaaac agcctctgac aagctgccag acaagcttca
    21061 gcagaagctt tgggaggcat aagaggatag tcagtagttt tttcatcgta ataagcctaa
    21121 attctttcgt ttaggatagc ctttcttcct tgtggtaagc aatcggcagc caatctaata
    21181 gggcctctag ctgctgattc caataatacc attcgtgcct gccatgatcc ttacgataat
    21241 caatagtcaa gccaagcctt ctcaactcag caactgcctt ttcattggct tcaaacaaaa
    21301 agtcctcata gccacaccaa gcgtatagct gggtttgacc atcactttct gctgctatac
    21361 ttgtcaaata atgctttttg atatcaggag cattcaaatc tccaaaaaca ccctgccaat
    21421 aaggcagctc acctatacct tgctgtaata gcatttccgg cgaaaaatgc aaggccccag
    21481 aaaaggaagc agcataggaa aagcgattgc tttttaaggc ccatttaaag gcaccatagc
    21541 ctcccattga cagcccagca acaaaggttt tttcacgctt agtggtcata ttaggaaaga
    21601 aagaagctaa tagccgagga agttcctctg caatagcttg gtaataattc ataccgtagg
    21661 tggtatcggt ataccagcct aaatcagtcg atggcatcac cacgattaaa ttggtatggc
    21721 gaagcagcct ttcaatatta gtccgctttt gccaggaatt ttcatttcct cccataccat
    21781 gtaacagata aagaactgga atatcttggt agccttgctc ttctgggcta agctcagact
    21841 gatcagggta gatcaccttg acatgtcttt ccatagccaa gatctctgaa tgatactcaa
    21901 tgctaatgct tgccatcagc tcacctcctt tttaatatca ccaaagcata aggaaagccc
    21961 actcttaaga cctaaaagcc agatcctatt tgaccagctt ttaggcaggg ctgtatctgt
    22021 attaacggac ctccataaca accggaagaa tagctggccg acgcttggtc tgctcaaata
    22081 aaaaccttga gagctcctct ctaacagagc ctttcaattc actccaatca aaatgatccc
    22141 cttgcagata attgccaact gttgtgttga ccaattcagc actttctcgt aaaatatctc
    22201 tgctcttttt cacatagaca aatccgcgag tgttgacctt agccttagag ataatacgtt
    22261 tttccttttt agatactgtg atcgcaacaa taaaaatacc gtcctctgat aagaccttac
    22321 ggtctctcaa aacaatattg ccaacatcac caatggcatt tccatcaatc atcacatcac
    22381 tagcaggaac cgcaccctcg tgtaagaagc catcctcatc aagcaccatg atgtcaccac
    22441 gcttcataat atgaatattt tcaggtagta taccagcctc ctcagctaaa tgagcatgag
    22501 cagctagatc gcggtattca ccttgaatcg ggaacaggta ttttggtttg acgagattaa
    22561 tcatcagctg caggtcacgc gcattggcat gtccagaaac acgtaaatgc tgcgtgatga
    22621 gcttaacaga gccacctgct ttatagataa ggttttcaac acgagcaacc attgcttcct
    22681 tggcagcgct tggcgttgtg acaatgtaaa ccagatctcc gtccttgatt tgcacgtggc
    22741 gatgacgccc tattgccatt ttctgtaggc tattaatcgg ctcacccata cgtccagcct
    22801 ccagaacaat caattcgtga tcctcaaact tagacatatc ctttggcttg attaatagct
    22861 tttcatcagc aatcactagc tttttaagac gaagtgctgt tctgacaata ttttcagcgt
    22921 cagtacctgt cagtaccact cgcctgctat aggctgctgc agaatcaaag acctgctgga
    22981 tacgaacaag atttgaagcg acagctgcaa tgataatccg cccgtcggca tgagcaatca
    23041 ccttatccat ctcctcgcca acctcagctt cgctggcagt ctgctcattg cttgtggcat
    23101 tggccgagtc agctaatagg gctaacaccc cttcttttcc aatgtctgcc aagcgagcta
    23161 ggtctgtctg atagccctca cgcgaagcct ggtcaaactt gaaatcacct gtatagacaa
    23221 tattcccctt atcggttcca ataaccacgc ctaaactttc aggaatagaa tgtgttgtct
    23281 taaagaagga aaccaagcca tctttaaatt caatttctgt gtcactgtcg accacatgga
    23341 aattcttaaa tctcttggtg ctattattgg ccttgacaaa caattttgct agctcgatgg
    23401 tcaattctga accaaatact ggcactggaa cctccgccaa caggtaaggc aaagctccga
    23461 tagcatcagc atgcccatga cttaaaaaga ctccctgaac cttgtccttg ttttcaatta
    23521 cataatcaag acttggaatt accaaatcta cacctagctg ttctgtttca gggtatttca
    23581 agccagcatc caaaatgaac atggaatcgt taatctctac tagatagaag tttttcccgt
    23641 actcacgtac gcctcctaat gcaataatgt ttatatcagt catgatactc ctttttttat
    23701 attagttatt acaaacggtc cttactgggt aagtcgaatt actgtcttgc agctaagctg
    23761 cactctttta cagtatatca tattttaggg cttattacct caaattgcct tgagactttc
    23821 tcaatctttt caatagatta tcaaaaaagc caagggaagg ctttcattcc aatggctttt
    23881 agagtattta ttttagtcaa aaagctggta ataatcagca atggtcattt gagattttct
    23941 cttctgatca aggtcttgaa tgattttacc atttttcatc acaatcaggc gattaccata
    24001 gttaagagcg tcctccatgt gatgcgttat cattaaggct gtcaagcgat ccttagctac
    24061 aaaatcatca gtcaaggcca ttaaggcttg gctggtctta gggtctagcg ctgcagtatg
    24121 ctcatctaat agtaaaagct ctggtctttt tagggttgcc atgagtaagc taagggcctg
    24181 tctttgaccg cctgataaga gaccagtcgg agtctccaga tgattttcca agccatttcc
    24241 aactcgcttg accaagtcag caaagtctgc catataatgg ctaatcctgc gtgatgacaa
    24301 gcctcgcctt tcccctcttt gccttgcaat caaaaggttt tcagctactg tcattcgagg
    24361 tgctgttccc attttaggat cctgaaaaac acgtgatagg tagctagctc ttttttctgc
    24421 tggcaggtgc gtcacatcat gccctaaaag cttaatttga cccttgctta acaatagcgt
    24481 cccagcaatc acattaaaaa gggttgattt accagcgcca ttcccaccaa gaatcgttaa
    24541 aaaatcatgc tcataaatgg tcaaggaaac atcatctaaa atagccttag tctcatcaaa
    24601 gccattattg acttcgacag tagcgtgaat taattcaata atttttctca tcgtgataag
    24661 ctagcctcct taataattgc tttttttagc acaggcacca tcaggcaaag tgctaatata
    24721 atggcactaa atagcttaag ataatttgta ttaaagccaa gagcaataac tactgagatt
    24781 aaaaattgat acaggataga accaaccaca atggctatca agcgctcaag cagggttagg
    24841 cctgtagaat ataaaacctc accaacaata atactcgcaa ggccaattac aatcacacca
    24901 atcccctttg aaacatcagc atagccatct tgctgactaa ccaaggcacc agataaggct
    24961 atcaaggcat tagagatcgc taagcccata agctccatac gatcagtatg aatcccaaag
    25021 ctcttagcca tatcccgatt atctcctgtg gcaatataag cctgaccaat attggtgtaa
    25081 agaaaataca ttaacaaaaa aatcaccaat gtagctacaa ccaaaccagc taccaacaca
    25141 ttggtgtcag ctgcaaaggg aaggtagtcc tgaatgcgct tgatatcatg caagcccaaa
    25201 ttggccctgc ccataaccat aagcataatg gaatggcagg aggtcatgac tagtatgccg
    25261 gcaagaagtg ttggtatctt tccttttgtg tataacaggc ctgtggcgaa gcctgccaag
    25321 gcacccgcca gcatagcagc cagagtagcc aggataggat ttaaaccgag attgagcaga
    25381 gttactgcta cagcacctcc taaaggaaag gacccttctg ttgtcatatc tgggaaattc
    25441 aatattctaa aggtcaggta aatccccaag ccaagaattc cccataacaa gccttgtgat
    25501 acagatgaaa taatcatatg aactcctttt ctattgctta cctgtaaggt cagaacgctt
    25561 cagcaggtct tttgagatca taagacctaa atcccttgct gcctttagat ttaaaaatgg
    25621 cttaccgtca tcaactacct cgacaggaac ctctgatacc tcttttccag ccataagctg
    25681 cagcacctgc ctagctgtct caacccctaa ttggtattga ctttgtgaaa tagaagcaag
    25741 actcccttgc tcaaccattg tatcaacact tgagtagacc ggaagctgtg ctgcatttga
    25801 ggcaacaatc accgctgaaa aagcactggc aatagtatta tcctgtggga taaaaacagc
    25861 atctaccttc tcagtcatca cagacatggt cgtggtaacc tcatttgttg aggggacagc
    25921 gtaagctaga acctccaagc cttgcttttc tgcaagagct gtaaagtcct tgacctgtga
    25981 tattgaattg tcctcactgc ttgcataaag gacaccgacc cttttgacct gaggggtcat
    26041 ctccttgatc agatcaaccg tctgtcgaac aggaacctta tttgataagc cagtaacatt
    26101 tgcctcaggc ctgtctaagt gcttgactaa tttagcacca actggatcag aaatagctga
    26161 catcacaacc gggatagtct tggttgctgc tgctaatcct tgagctgcag gcgttgcgat
    26221 gccaacaaca atatcgtttg ttttgaccag ctgcttgctc atggtctgaa tcttactttg
    26281 atctccttct gcattcataa gggtaatgct gaccttttgc tctggctgat gatgcttctt
    26341 tagctcgtct ttaatgccct gtgcaatctg gtcaagcgcc tcatgagtaa ccagctgcaa
    26401 tataccaacc ttaaccacac gcttgctggc taactgtggc tgttttttgc cctcttttag
    26461 cactagcgaa gcagcaacca ttaaaaagag tgcaatgact gttacgataa gacctttatg
    26521 tttcatgttc tacctcttaa tttccattct tactccgttg ctaacattta gagtactcac
    26581 aaaaagaaaa aacgcttagt aatcagctac taggcgcttt ttttgaaatc caatgtcagc
    26641 gcatagatac ctttttagaa gtactctaaa agtcgtatct atgctaaccc ataaacacaa
    26701 ctttatctat gccagctttg ccaatttatc atatgctgtg tttgcttcat cttggatttc
    26761 ctttcttgtt tttttacatt ataacctaaa agctcaaaaa tacaagagca tttgaacata
    26821 tttttccatt attttttgtg gtataatgaa agaattagaa ctcaggaggg agaaaccatg
    26881 tcatttgacg gctttttctt acatcattta actcaagagc tcaaccatag tattgttaat
    26941 gggcgcattc aaaaagtcaa tcaacccttt gataatgagt tggttctgac tatccgtaac
    27001 catcgccaaa cttacaagct cttgctctca gctcatccgg tttttggacg cattcaactg
    27061 acccaaacag actttcaaaa tcctcaattt cccaatacct ttaccatgat catgcgcaaa
    27121 taccttcaag gagctatcat tgaaggcttt gagcagattg ataatgaccg catcatcgaa
    27181 atgaccgtct ctaacaaaaa tgagattggc gatgccataa agacgacatt gatcatcgaa
    27241 attatgggca agcacagcaa tattattctg gttgaccgtc atgaaaacaa aattatcgag
    27301 tctatcaagc acgtcggctt ttcccaaaat tcctaccgga ctattttacc aggatcagcc
    27361 tatatcgagc ctccgaaaac aactgctgtc aatcctttta cgatctcaga tatcgcttta
    27421 tttgaagtcc tgcaaacaca ggagttatct gctaaaaatc ttcaaaagca tttccaaggg
    27481 cttggccgag ataccgcaca agagctatcc agtctcctga caactgataa gctaaaacgg
    27541 tttagagact tttttcaaag acctagtcag ccaagtctaa ctcagacctc ctttgctcca
    27601 gttgccttct caaacacact gaagaccttc cagaatctat ctcagctgct agattattat
    27661 tatcatgaca aggctgagag agatcgtatc aaccagcagg ccagtgacct gatccaccgc
    27721 gttcaaaacg aattggaaaa aaatcgcagc aaactgatta agcaagaggc tgagctgcta
    27781 gccactgaaa atgcggagga ctttcgccaa aagggtgagc tcttaacaac ctatctgagc
    27841 ctggtgccaa atgaccagga ttcagttgag cttgataact actataccgg ccaaaaaata
    27901 accattgcac ttgataaggc gttgactccc aatcaaaatg cccaacgcta ttttaaaaaa
    27961 tatcaaaaat taaaagaagc tgtcaagcac ctctcaggtc tcatcgctga cacgcaacaa
    28021 accatcgctt attttgaaag cgttgattac aatctatctc aggcaacgat tgatgaaatt
    28081 gaggacattc gagaagagct tattcaggct ggctttgtga aaagccgtaa gcataacaag
    28141 caccacaaac gtaaaaagcc agagcaatac ctggcttcag atggcaaaac aattattatg
    28201 gtcggacgta acaatctgca aaatgaggaa ttaaccttta aaatggccaa aaaaggcgag
    28261 ctctggtttc atgctaagga tattcccggc agccatgtga tcattaagga caatctaagc
    28321 ccaagcgacg aggtcaaaac tgatgctgct gaattggcgg cctattattc taaagcaaga
    28381 ctttccaatc tcgttcaggt ggacatgatt gaagccaaaa agctgcacaa gccaagtggt
    28441 gcaaagcctg gctttgtcac ctatacagga caaaagacac taagagtgac acctatagaa
    28501 agcaagattc aagccatgaa gtgctcccct tcagcctctt cctcatagga ctacagcaat
    28561 aaagataaaa aaagctacag cctcacactt ggagataggt ccagtcttaa agctgcggct
    28621 tttttatcat tacttgttaa tcatctctca aatcatctaa gaagccttgc atatgaatat
    28681 catctggaac ctgctgcaaa tacctttttg cctgcttaac tgcttgatca gtatagccga
    28741 attcccttaa taaataagca taatcctgta aaaagtcagg attttctttt aggtctcctt
    28801 cgatatcttt atagatagtg agggcttttt cttgctgctc cagagcctga taggccttgg
    28861 caagattcca tttagttagc acatgatcaa tctcctcatg ctcaagagca atgacctcct
    28921 caaaacgctc catatccaag tacaggctag ataagcgcat gatgacctct tcgtcatcaa
    28981 cagctacttc cttggccctg agcaaatacc gctctgagcc agctggatca tgcaattcaa
    29041 aggcaagctg tgaagcaagc aacagcagct gggggtcaaa ggcattttta cgcagaccct
    29101 gctgaactag gcgtaaggcc tcttctgtcc gatgctcctc acgcaagctc atggcatagg
    29161 ggtactcgta gcctaaaaag tctgcattca tcgtttctaa ttgcttgaaa tagagattgg
    29221 ccttttggta agcagcctga tcatataaaa tcgtcgccag ctcaaacact gtctcatcgt
    29281 catactcaat ggcaagagcc ttttcaagaa actctacagc agcttcaaat ttccctaaat
    29341 aagcataggc acgccctatg cgctggtagg ttgagatacc tgtcagctca agaatgtgac
    29401 gattatcaag cctagcatat tgctcaatag cctcgctaaa gtgctccaga gacatctcga
    29461 tttcggctaa gccaaagatc actatcggct cctgactcaa ttcagctgct tgaagtagct
    29521 tctcacgcgc cacatcagtt agcccctcca aatcataaag atcagccatg acgagcagag
    29581 cagacaaata atcagcacta tcctctggaa tcctatcaag gtacataaag gcctcttcaa
    29641 tgacattatc ctcagctgca atctgagcaa gattaatatt gacctccgga taagcctcac
    29701 agacctgcaa ataaatcgtc ttagcatgca gtaaaaaacc aatactctct aggtattctg
    29761 ccaaagccaa caaggtctca gcatcgtcct cctgcaaggc tctttgaaaa tagctttctg
    29821 cctgctctaa atcctgttgc tctagtgagg caatcatttt ttcactattt aacatcttca
    29881 gcgaccctct cagcttctgt aggctcttcc tcatacaggc ctgtaatatc cttgtaccaa
    29941 tcaaatagct ccttcacaac aaccttaaca gaagcataaa ctggaatgac aagaaagaca
    30001 ccccagaccc caaacattga ccctgctgtc aataataaaa acataatggt aatcgggtga
    30061 atgctcagct tatttccaag cactagcggc gcgacaaaac gtccttcaat cgtttgttca
    30121 ataacaaaaa taatcaacac cttgatcagc atcaagggtc cttgcaccat tcccataatc
    30181 actacaggaa tcatggctaa aaagctcccc agataaggaa tcatattaag aaagcctgca
    30241 ataataccaa aggtaataga atagttcaaa ccaacaaggc taaacatcac tgaaaacatg
    30301 agaccaacca caatcgcaac ggtcacctgt ccctgcacat agccagataa ttgcttgttg
    30361 atttctccta agacacgtgc cataggctgg cgcagcttaa tcggaagcac attgaccaaa
    30421 ccatttttca tatggccact gtcacgcaga aaataaaaga gaataaaagg tgacatgatg
    30481 attgcaacag taatacgggc aatagctcca gcaaaatttc ctgcccaatc aatagcattt
    30541 ttagagaagc tttgcgcata atctagagcc ttttggctca tactagtcag catatcctgc
    30601 aggttggacc tgtagctaac cagccattcg ttttcaagta gcttattagc ctctagattg
    30661 accttggcaa catatttggg aaggtcttcg acaaagctcc ttagctggtc ttgaatcata
    30721 gggataaagc cagaaatagc ccagaaaaat aggagaatta ctaagccaaa gacaataaaa
    30781 atagaggctg tgcgatttgg acctagcttc tcaaccatat caactaatgg cttggtcaaa
    30841 taatacagga tagttgagat aaccagcggc agcatgataa tggccaaaaa tgacaagatc
    30901 ggtgtaaaga ggaaggatat ttttgtaaag acaaaaatag tcagaaaaac cagcagcgtg
    30961 attaacaaaa ccatcaccgc ctgattattt aaaaaccatt tgtaaaatag actatcatga
    31021 tgattaggct tagaatgcaa tgacattaat ggtatcgtcc tttcttaatt gtggcatcat
    31081 tctgatgaga gcttttaggt tagttgactt aataaaaggt gactgttttt tccactagct
    31141 tgttgtggtc atcataccta aatttagcag aaaaaaacgg ccggtcttcc agtatccact
    31201 tgaaaatgtc gtaatctccc tcccaggttg gcttttccag cacctgatca tagggaaccc
    31261 attctagggt cccttctctg gactcctcat cagcaattaa gtcaccttca aagtctgtca
    31321 ccttaaacac gtaagtatac caatcatgcc ctggtgtaaa atcaggaaag gtaatcactc
    31381 ccttaaagtc cattgctttt accagcaggt gagtttcctc taaaatttca cgtctggcac
    31441 agtcatcagg agattcgcct ggctctaatt tgccaccaac tgaaatccac ttaccttggt
    31501 gaacatcatt ttccttcttg ttgcgatgca gcagcaataa agcctcaccg ttatcaatat
    31561 aacaaatcgt tgctaactta gtcattcata cccttccttt gtttagttgt tactattata
    31621 ccaatctctg agaaatatgc catcatttta tcatttaagc acatcaaaca agaaaaccac
    31681 aatcactaca actcttagcc ctgtactagc aaaaaagcct tgataaggca acgtctgctg
    31741 actcatcaag acttatcact atttaacgaa tcacttcctg tgtcttagcg taattggctt
    31801 caactgcttc tttttcggaa cgccaccaat cctgatgatc agtataccat tggatcgttt
    31861 gctcaagtcc ttctgaaaaa tcagtaaact gtggctccca gccaagctcc tgacgaagct
    31921 ttgtcgaatc aatagcatag cgtaaatcgt ggcctgcacg atccgttaca tggtcataag
    31981 cgtccttagg ctgccccatt ttatccagga ttaattccag cacttcctta ttattttttt
    32041 cgccgtcagc tccaataagg taggtctcac caatacgtcc cttggtcaaa atggcccaaa
    32101 caccagttga gtggtcattg gtgtgaatcc agtcacgaac attctttcct tcaccataca
    32161 attttggctt gataccagac aagatattag tgatctgacg agggataaat ttctcgatat
    32221 gctggtaggg accataatta tttgaacagt ttgaaatggt tgccttcacg ccaaaggagc
    32281 gaacccaggc cttaacaatc aaatcagagg ctgccttggt tgatgaataa ggtgacgacg
    32341 gattatagtt agtatcagcg gtgaattttt cacctggccc ctcaccatga cctggcaaat
    32401 cctcacgcag tggcagatcc ccataaacct catcagtgga cacatgatgg aagcgaatat
    32461 catatttacg agccgcctct aagagtgtat aagtcccaac gaagttcgtg taaataaatg
    32521 gacttgggtc attgagtgaa ttatcattgt ggctttcagc agcatagtgg acaatagcat
    32581 ctgccttagc ggccagctta tctaccaatt cagcatcagc aatgtcacca acaaccaact
    32641 ccacgcgatc acccaaaatc tcctcaaggt tggcacgatt gccagcgtag gtgagcttat
    32701 ccaaaacagt tacgtgaacc tctgggtgat ggttgtaaac ataatgtacg aagtttgaac
    32761 cgataaagcc agcgccaccg gtaacaataa tgtttttata ttcagacatg ttttttcttt
    32821 tcctttgttt tcagctatca gcactcaaaa tgcagcttaa tccgacaggc aagctcagtt
    32881 accagtgaaa acagcgacta agctgcctca cctcattgct cctaccatcc ataaggtcct
    32941 tcctatcaga aggatacaga gacactccca tcaaaagcca tagcttattt caaatgctaa
    33001 ttatgataaa tcttcttgtc tcaaaggctt aacggcctct aggaagggat ggcttttatc
    33061 tgcttctgaa acctctgctt gttcaagact ttcccacgca atcccaaggc ttgggtcagc
    33121 ataattaaca aaggcatatt tttgcttgag ctcaagcgcc caataatcat tgaccagata
    33181 ggtataagcc accttatcag tcagtacttg aaagccatta gcaacacctc gagggacaaa
    33241 aatccccttt gaagcgtcaa tgactgtttg ataggtatgc ccaaagctat caccctcacg
    33301 aagatcaacc caagctccaa gaaccttacc ctcatcagca acagagatgt acttgtccca
    33361 aggctctgca tgcaggcctc gaagcacatg cttgcgcgaa aatgaaatat tgttttgcag
    33421 cttacctgcg gcaaaaaact gctcaggaaa gcctagagga atcatttttt ccttttgaaa
    33481 attttcctta aaccagccac gattgtcccc tcgaacaggg atatcaaact ccaaaagtcc
    33541 aggaatggct tcaatttccc gacaggctaa ggctttatca aaaaattgtt ctgtcatcaa
    33601 gcttctccaa tcaaccgcag caggtactgc ccgtattcgt ttttcttaag cgactgcgct
    33661 agctggtaga catcttcttt agtgatataa cccatgcgat aggcaatctc ctctaggttg
    33721 gccacctgag cgttttgcaa gcgttgaact gtctcgatgt attgggcagc ctccagcagg
    33781 ctttcatgag tgccagtatc tagccaggca aagccacgtc ccatcaactc aaccgatagg
    33841 tcgccacgct ctaaataggc tttattaaca tcagtaatct caagctctcc tctggcactt
    33901 ggtttaatgc ttttagcaat ctcgactaca tcattgtcgt aaaaataaag gcctgttaca
    33961 gcaaaatgtg acttaggaac tgccggcttt tcttcgatag aaatggcatt catctcatcg
    34021 tcaaactcca caaccccaaa acgctccgga tccttgacct gataaccaaa aacagtggct
    34081 cctttttcct tagctgctgc cttttggagc attttcgtaa ggccgtttcc atgatagatg
    34141 ttgtcaccta aaatcaaggc aactcgatca tcaccaataa actcctcacc aatgataaag
    34201 gcctgtgcta agccgtcagg acttggttgc tccttgtagg acaagcttat cccaaactct
    34261 gagccatcgc ctaatagctc ttcaaatctt ggaagatctt ggggagttga aataatcaaa
    34321 atgtctcgaa tccctgccag catcagtgtt gataagggat aataaatcat tggcttatca
    34381 taaattggca tcaattgctt tgaagctgca cgagtaagag ggtacaagcg tgttcctgat
    34441 cctcctgcca gaataatacc tttcatcgta gctctcctca ttttataata cgtcactatt
    34501 ttatcatttt ttaaaaacag tgtcactttt tatcattaat ccgacgaata taatgatgaa
    34561 tcgggtattg actagtatct aagctagctt tttgccccaa aagcagggca atcagctgct
    34621 gagcaatcaa aggacctagg gtcaagccag atgagcctag accgcttgcg gcgtaaacac
    34681 ctggtagctg aggtacctgc ccaaaaaatg gagaaaaatc tctggtatag gctcgaatgc
    34741 ctacgcggta agaaacatca gaggcagaac tcagcttagg gtaataggtc aaggcctcct
    34801 gctccaaggc ctctaaaaca gctacatcag gctcaaggtc atagccctta tcattttcat
    34861 gactcgctcc tacagacaac ctatcatgct caaagggaat aatatccagc tccccctctg
    34921 gcatgaccac tgcgtagtta tctgtagtca cattcgcaat gtgataatca atgagctgtc
    34981 ctttttgcgg tcgaatatcc acctgatagc caagtggctc aagcaattct ggcagccaag
    35041 caccagcggc tagaatcagc cgatcaaaga ccataccatc aacgagatag ccttgctttt
    35101 ctatgcttat gccaacacgc tttttaacca cctgatagcc actagcttca agcaaacact
    35161 gacataggtc tgccccatca acacgtgcag ccccagaagc ccataccagc tgctcaaaac
    35221 cctgtaaatc aggaaaatca accctaatgt ccgaacgaca ccttatcgcc aaatctccaa
    35281 tcaaaggcga ctcttgcttg cgtctaatgg ccagctggta gagctcctct agcttgtcct
    35341 cattcttttt taataaataa acaccagtct gcttataaaa atgtgtagaa agcccctctt
    35401 tttgcagctc cttgattaag tcctgataac aatctgctcc taaccgagcc agctggtacc
    35461 aagccttatt ccttcttttt gaaaaccaag ggcagataat gccagcggct gccttagttg
    35521 cttgaccatt accatcatca aaaatagtaa cctgctgata cccttgtttt tttaaataat
    35581 aagcggcgct tgaacctaca attccagctc caatgattgc tatcgttgtc attgccgttt
    35641 ccattctatc atactgctta ccaagcatag gccatactca gtcatgctat agatgactaa
    35701 agggatttgt tgacgccttg ctagccataa tggttacttg ccagccttcc tcttttttcc
    35761 aagcctgcat cttggcaagt agtttatcaa taaataagga ctcgatgtga tgccctggat
    35821 caattgccag caggccttct gtcagcattt cctgtgctgt gtgataataa atgtcaccag
    35881 taatataaac ttgagctccc ttagcaagcg ctgcctgata aaatttatca ccactgcccc
    35941 cacaaatagc cactcgcgaa atcaaagggt tttgaccagt atatcgaacc agccgaacca
    36001 catcaagccc aaaggcttct ttaactgtaa gtcctaactc ctccaagctt tgctctgcta
    36061 catttccgac acgtccaata ccatacccat cttgcgtctc aaccaatacc tctgtctgct
    36121 caatgcccaa cagctcacaa aaccaatcgt tgagcccgtc agagacaata tctatattgg
    36181 tatgactgac atagacagaa atatcgtgct tcaccagctc aaggacaata tctcgctgtg
    36241 gcgaggagac caagtccttc aagcccttaa aaataggagc gtgcttggtg ataatcaggt
    36301 ctaccttggc cgcaatagct tcggcaacgg tattttctct cacatcaagg gtgatcatta
    36361 cccttttgac ctccttatcc agagagccaa tttggaggcc acacacatct cctgacatgg
    36421 atagctcaag cggacaatag ctttcatatt tttcgatgat tgttctagct ttcatgactg
    36481 atgacctcct caatcgcttt tattttttga gaaatgctag cgcgttcaac aggcttcgtt
    36541 gctggcacac aagacagggc atagacaagc ttatctcgct ctttttgcca tttagccaca
    36601 aagactgatg acctttcctg agacaagaaa ggaccaaagc gctgctcctg atctgttaga
    36661 ctttgttgac caggctctgc aacaatgatt tcataatatt tgccattttc tgtcatgatg
    36721 gtttcagcac taatacaaaa agcattggca gatagccaag cacgcagctc atcctctcga
    36781 ttattgggct gtaaaatcaa gcgctcaatc ccttgcagct tttccttacc agccgctaaa
    36841 atgtcagcta ttaaacgccc tcccatgcca cagatggtta tgcagtctac agcatctctc
    36901 gcctcaaagg cagctaagcc attagccaga cgcacctcaa tatgctctgt caaaccatat
    36961 tgtgacacat tttttagggc tgatacaaaa ggtcccttga ccacctcacc tgcaatcgcc
    37021 tcttgaatat gctcggtttc aaccaaaaaa ataggaagat aagcatgatc acttcccacg
    37081 tctaaaagct tagcaccatc agggacatag gatgccacat ggcgtaagcg ctttgataaa
    37141 tgactttcca ttttcttaat ccttctaaca actaatcgta tcactattat agcaaaatac
    37201 agaccaatta aaaagaaagc cacatcagac cttcttttta ccataggtag tcttgtaata
    37261 gctgcaatag ctctgtactg ggcaggtatc acacttagga tgcttagcca agcagtgata
    37321 gcgtccaaaa aagatcaaac ggtggtgggt gatgatccaa tccttcttag gaagcttggc
    37381 catcaaatca gcttcaattt cagtaacatc ggcatctggg gcagaaatgt tcaagcgctt
    37441 ggcaatcctt gacacatgcg tgtcaactgc gattgcaggg acaccataaa tctctgccaa
    37501 gaccacatta gcagtcttac ggcctactcc tggtaaggat tcgagctcct tatgggtttt
    37561 tggtacctga ccatcaaact gtgtcagtag ctgctgagct gtcttgatga tattttttgc
    37621 cttattttta tacaagccaa ttgtccttag gtgatcctca acatctgaca catttgcctg
    37681 agccaaatct gaaagctctg ggtagctttg ccacagctta ggggtaacct tgttgactgc
    37741 cttatcagtt gtctgcgctg ataggataac cgtaataaga agctgaaagg gcttttcttg
    37801 gtcccaattc agctcgccct tagcctctgg aaacatctca ccaatgattg atagaacctt
    37861 ttttaatcgt tctcttccta tcctcattag ttactccaaa ggttcatcgc cgcaagaaaa
    37921 tcatctgaaa ccgtcacttc agacgccgtc atatcctctc tggcacgctt tttttcctca
    37981 agctgcctga ggcttgtaat tccctccttg cgccaatttc ttagaatagc ctgaatatat
    38041 ttccaattgg tttttccatt aaagacagcc tctctcagcg cctcacgcac taaatccaga
    38101 tctgtttggt catcatgaat ggttttttcc aaatcctcta gctccatcgg actcaaaaaa
    38161 cgacccagct cacgctcaaa ctcatcaaca agaagtttca attggttggt gttttgctgt
    38221 tcatgctcac ccttttcatc acgcgccaat agctggtcta aagtgactaa tacaggacta
    38281 gcatcaaaaa tgatctcaat ctctccagcc agctctatgg ttttcatatc taataacccc
    38341 tgactggtca aggaagaaat agccttattc acctctgcta cagacttacc caaggcatta
    38401 gcaatctgac taggtgccaa ttcgtcaagc ctagtcgtat tttggagata gaaaaactgc
    38461 caaaccaaaa aatcgtctga gctcttaaaa atatccttgt aatgaaacag taaggcagtt
    38521 ggaaggacca aattgccaga ctgataatgc tctaaaaaac tcataattcc cctgccaaac
    38581 gtaatagccc aacctagctt ttaatcagta ctgccattag caagcactga ttaaccagga
    38641 aaatgcatca ataccttaca atcgtaatca ccaatagcct gacgaccatt caagccgtcc
    38701 agctcaatga gaaaagcgca gccagcaaca atgccgccca gcttttcaac cagatcaata
    38761 gtagccttta ctgtaccacc tgttgctaat aagtcgtcca caataaggac acgttggccc
    38821 ggcttaatag catcagcatg catggtcaag gtgtctagac catactcctt ttcatagcta
    38881 gcagaaatca cctctcttgg caatttaccc ggcttacgaa caggagcaaa gccaattcct
    38941 agctcaactg cgaccggaca gccaataata aagccacgag cctccggtcc aacaatcatg
    39001 tcaatgtcct tatcgcaggc atattgcaca atctcacgaa tagcatagct gtaggccttg
    39061 ccactagcca ttagcggcga aatatcacga aaggtaatcc cctcctttgg gtaattctca
    39121 attgaagcaa tatattgtgt taaatccatc gtaaaatagt ctttctaatg tcttttaaat
    39181 taaaatcttt cctattatag catgaaagtc taaaaaggta aatgattcct aatcatccag
    39241 atcaatccct ttttccttta aattagtcag gcattcctgt aaataggcct cttgatgctc
    39301 aggataaatc ggtgaggtca gtgccacctc ctctaagtcc tcataggcgg caaggctttt
    39361 tcctcggtaa tttttatcct gccagctcac atctggctgg tagccccgcg cctgcatttc
    39421 ctgcataatc aacaggtgat actggtaaag cttataaaga gaatgggcaa acacatagtc
    39481 aaccgtcgca tgtggtctcc cccagcctgc tcctcgcaag gccgcacatt cacgatgctg
    39541 ccccaacaat tgctgccttg gtaggcgtgt gattaaatcc tgatgccaaa gacgcataag
    39601 ctctcctatt tctcttcact agtcattaaa tactgataaa tctcctgcgg actgcccaag
    39661 gccataagct cttgaaactt taccagctct tttagctgtt ggtaaatgac actgtcagcg
    39721 atgctacgtt ttggggcatc agtctttacc ctcatcagcc catcttcgat tactacaaag
    39781 cctaactcct caaaaatttg tatcattttg accaagagga ttttttcaat cttgaggtaa
    39841 tcacttagca aggtcagctt atggcgaaga tcaaattctg ggtattgata gatggtctta
    39901 taaagcttgg caaattgctc tctactgcca tagcctgtta ggtaataagg gcgcttaata
    39961 tgatttttaa agtaaatcgc ttcaaattcc cgatgtctaa aaaggccttt caaggcatca
    40021 atatcgtcag gaacctcatc tatgacaaca accttggcct gctggtcctc aacagctgta
    40081 ggaatatgct caggtgccct agcagtcctt gctcgaatat caaacagctg caccccagtc
    40141 actctagcgt caaccagcat taattgcagg ctagtatgac ctcgccagtg attgatcgca
    40201 agactaaccg ctaattccaa gccctgtgat tgctggtact cctgtatcag atgtccctga
    40261 ccaaaggcca agacatcagc ctcaacggct cctttgctga ccttgaactt caagtgactt
    40321 tgttgctgac caatggtcct tgcctgctta atcgtaaaat cttttaagta aaaaacaggc
    40381 tttttattat ccatgccaaa gggtgctaga agtagcagct tgttcagact atctatactc
    40441 aatgcttcta aatccaattc accattgatc aatagagtgt ttttttcctg accatcgtgt
    40501 cccttggctg ccacgtattg gcaaagtagc tctgatagct cctctaggcg atcagatggc
    40561 agagtcatgc ctgctgcccc ctcatgacca ccaaaggctg taaataagct cctattgcta
    40621 ttaagtgctt caaagatatt aatgctctct aagcttctgg ctgagccctt ggctagcccc
    40681 tcatcaatgg tcaaaacaag aacagtctgc ccaatctcct ccatgatccg accagctaca
    40741 atccctaaga cccctgggtg ccagccagac ttagctaaaa cctgcacagg cttgtctaga
    40801 tcaagcatag ccattgcttg agcaaaaatc tcctgtacca agacctttct ttcctcattt
    40861 ttactactaa tcatcaaggc aagctcatga agctcttcgt catcaaagcc tgtcagtaga
    40921 tcaatagctg gatttggatc gtcaagacgc cctagagcat tgagctgcgg agcaagctta
    40981 aagctaataa catcttcatc aaaatgcgct aagtcaacct ctgaaagctt catcagctcc
    41041 tgcaagccta gtctttctgt ctcttttaga acagccagcc cgtttttgac aaggatacgg
    41101 ttttcacctc gtaggctgac catatcagca attgtcccaa tagcaaccag atctaaaaag
    41161 tctactggaa ttgtctctaa cagagctgaa gccaacttga aggcgacgcc acagccagct
    41221 agtttttgaa agggataagc agcagctggg tgctcagggt gaataatagc aaaggcatca
    41281 ggtagctctg ctggcaggct gtggtggtct gttacaataa catctacccc ctgtgcttgc
    41341 gcaaaggcaa ccgcttcatg gcctgaaaca ccattgtcaa cggtaataat cagcgaaacc
    41401 tgctcttgct cgatgaaata cttgtaaaca ctttgattgg gaccatagcc atctgtaaag
    41461 cgattaggca aataaacaag aggctctgct cccatcattt ccagcgtttc cttgacaata
    41521 gacgccgctg tcatgccatc tgcatcataa tctccgtaga ccaaaatcct ctcaagcccc
    41581 tcaatggcct gacgaatgcg atgaacagct ttttccatat catttagcaa ataagggtca
    41641 tggagctgtg ataggtcagc tgtcaaaaag ctggtaagct cctcttcggt atgaacacct
    41701 cggtcataga tgagctttgc agctgtctga ctaagtccct ttgcctgagc tagcttaaag
    41761 aagccagcat ctggctcctt atcagctatg gtccactgat atttggacgt aatcatttat
    41821 aattaaatac ctttcttgca agataatcag atatagttgg aaacaaggta taacacttat
    41881 gagcaagggc taggctaata ggcagattaa tctctcgttt cttttttcct attgcagcaa
    41941 tgattttttt cgccacagta tccgcctgca gcgtaaagcc tgcaacactg gctaaatact
    42001 gcccgcttgg gtcagcctgc tcaaaaaagg aggttgcaat cgggcctgga ttaacagttg
    42061 tcacataaac ctgcctttct gccagctcca agcgaagggc attagaaaag ccaatgactg
    42121 caaactttgt cgcagaatag atacttgact tggcagaagc tattaagcct gccattgaga
    42181 caatattcat aatatgtcca gagccctgct ctgccatttt gtggccaagc aagcgtgcaa
    42241 aatgaatgct ggctaagcta ttcacacgaa acatggcctc aatctcttct gcagagaaat
    42301 catcaaaggc cttaaaagca ccaaagcctg cattgttaat caaaacatca atcctgccat
    42361 ggcgctggta aagctcatca acaagagcct caatagcagc agggtcttga atagcaatct
    42421 cgtagcattc cttattaccg cgagcctgat atagactgtc taacctgtct ttgctgcgcc
    42481 ctaacaaaat caggtaatct tctcttggaa gctgtctgat gatagcctgt gcgagcccgc
    42541 cagaagcacc tgttatcaga ataattctct gtgccattaa atgatcactt cctctaaatc
    42601 gcgaacaacc ttcacatttt caaaaatagt tgccgcatcc ttttccattt gacgacagtc
    42661 acgtcctaaa aagcgtgctg aaacatgatt cagtaaaaga cgcttagcac ctgcatcacg
    42721 cgcgatttga gcagcctgca tgtttgtcga atgcccatga ttacgggcca ttctttcatc
    42781 acccttcccg taggtggact catgcaccag cacatcagca tcttttgcca atctaacact
    42841 agcagatgtc ttgcgtgtat cgccaataat ggtgatgatc tttccttttc gaggctctga
    42901 aataaagtcc ttggcaaaaa ttttggtgcc atcctctagc tcaatatcct gcccattttt
    42961 aaccttgcca aaaagtggac caaagggcac tcctactgct ctaagagctt ctgcatcaag
    43021 tgttccttct aaatcctttt gaaccacacg ataccccata caaaagatgg tatgtgccaa
    43081 gcgctcagca taaacaataa atttatctgt ttctaaaatc ttgcccatag aggtgtcatc
    43141 aaactcatga taatgaatct gataaggcaa tttagagcct gatatcctga tgctgtttgt
    43201 tacataggat tttatcccaa caggtccata aatctcaagg tccgtctgct cctcactagc
    43261 ttgaaaagcc cgactagata aaaagccagg caagccaaaa atatgatcac catgcagatg
    43321 cgtgataaaa atcttcttga tttttcgtgg cttgattgtt gtttctaaaa tttgccgctg
    43381 ggttccctcg ccacaatcaa acatccacac ctcattgatt tcatctaata gctttagcac
    43441 taagcttgaa acgttgcgat gcttggctgg ctgcccagct ccagtaccta aaaattgtaa
    43501 ttccatacag tctattcttt ctaatgcaca aggtaaatca tgaattctct ttgtgcaaac
    43561 tgataatatt tctttccttt gaatgcttgg ctaagagcca acaattcatc actattaaag
    43621 ccctttagca gggtcatttc gtttgagaaa cgatagatcg tggttaacaa agcatgctca
    43681 ggtgttatgt cctctggctc tccttgctca aattggcagc tcttcatctt gattctacca
    43741 tcttccacat aaaccacgta ttgtggaaaa atctgagcca gctccagcag cagcgattcc
    43801 tcaggctgcc cctgctcttt ttcagcaaaa acaatcgcct cctgtgcttc attttcaaag
    43861 acaaagccat aggattgccc caacaaattt aagcggacaa agggcttcac ctcatcaaat
    43921 gacggctctg aggtaaacag cttcaaggcc cttgatagct caaaataata atctgtcgct
    43981 gcttttggtg attgcttctg atacatttct gcaaaataag cattaatcac acttgggggt
    44041 ggcgtgatgg tagctaattt ttgctggtct gtcaagccct ttaagcaatt ttgcaaataa
    44101 accgtatcta aactcgtaaa gcctccataa gtctttgcca attgaatata atcagtcata
    44161 aaattcttct aatctccatt tatttttggg agcaatgtag ccagaaatct cttcaatctc
    44221 cttatcaaag ctataaggct ccaataacgc caacctgttg aggtcatagc atttgtaggc
    44281 ttgatcctga cagagcttga tcgaaaatgg ctcaaacatg tcccgaatct gatcaataag
    44341 caactgtctt aagaggctac gactgttttt atcacgtgct gacagcctga catttggaaa
    44401 aacagttgca gtcaagctag ctgtcttatc catcttgtta taaatagcca gccttggaat
    44461 atccagcata tctaaatctt tcaagatgtc tagaacaacc ctctcatgct ccaaatgatt
    44521 agggtcactg gcatcaatca catgcaagag caaatcaaca tgccgacttt cctctaatgt
    44581 cgacttaaaa gcagccacga gctccgttgg taaatcttgg ataaagccta cagtatctgt
    44641 cagagttgcc tgaaactgat tttgcagata aatttgcttg gtggtggcat caagtgttgc
    44701 aaataattca tcagcctcat attgcttgtc accagtcaaa atagtcataa tagtagactt
    44761 acctgcattg gtatagccga tcaatccaat attaaagaca tcagaggtca tgcggcgatc
    44821 acgaatcgtt tgacggtttt tttcgacagc agctagctgc cgctcaatat ctgcaatctg
    44881 atgacgaatg gagcgccggt tcagctccag ctggctctca cccggcccac gactcccaat
    44941 gcccccggcc tgacgactaa gcataacacc ctgtccgacc agtcttggca gcatgtattt
    45001 gagctgcgct aaatgcacct gcaatttccc ttcatggctt ctagcccgca tcgcaaaaat
    45061 atcaagaatc agctgcatgc gatcaatgac cttaatacct aaggcgtcct ccaaattggc
    45121 attttgccga gccgttaaac gattgttaac aatcactgta tcaatctcat tggcagcaac
    45181 catttctttg atttcagcca gcttaccaga gccaacaaag gtcttgctat catagcgctc
    45241 cctcttttgc agatagcaat caacgacctc tgcacctgcg gtcttggcta gactagccag
    45301 ctctgtcatt gatagctcag catggtcagc tgcttgtagg accacgctta gtaaaataac
    45361 tctttcctgc cttgcctttg tctctatcat gaacgcgact aatcctccaa attccgtagt
    45421 gtttattata gcatagtttt agctattttc agctagtttg ccatcgatag cttcctaagg
    45481 ctccttcaaa aagcgctcca ccctatcata tattgcctgc ggataggacg actcgctaat
    45541 cgagtcaaag cgcactgcca tacggttacg aaaccaagtc agctgtcgtt tagcaaagcg
    45601 gcgtgtttgc tgctttagtg tggctgttgc ttcttctaaa ctagcctgac cctgaaagta
    45661 agggaagagc tccttataac cgatccctcg actagcctga acagctggat actgctcaaa
    45721 aagccacctt gcctcctcca ataggccaga agccatcatc agatccaccc gcttattaat
    45781 ccgctcataa ataacctctc gctcatcagt caagccaatg atcaaggggt tatagggggc
    45841 ctcttgattt tctaaatccc tagcaaattg atttagctca agtgagcgaa tggcacgcct
    45901 gcggttaacc tgatcaaggt gaatgccctt actagctaat agctgataaa gctctgtatc
    45961 tgtcagtgtc tctagctgct gccgataagc aagtagctcc ttttgatcaa gatctcctcc
    46021 tagatgatag ccctctaaca ggctttgcaa atacaggccg gtaccaccga caataatcgg
    46081 cagtttaccg cggctaacaa tatcttcaat agctcgctta gcgtcctgca caaaatcaaa
    46141 ggctgagtaa gactctgtca cctcacgaat gtcaatcaaa tgatgaaccg caagagcctg
    46201 ctccctggca ctagccttag ctgtcccaat atcaaggtga cgataaacct gctgactatc
    46261 tccagatata atttcaccat taaaggcacc agccaaggca atccctagag ctgtcttgcc
    46321 aacagcagtc gggcctacaa tcacaattat cttttctttt gtcatttatt gtctttctac
    46381 ttaaaaagca gctgaaaaag tcttttactt gaattttcta atctttttcg ctaccatata
    46441 ttataacata agattgagag acagttatgg tcctcttaat agaaatggag aatgattatg
    46501 gctaaaaaac atggattcgc aaagggtctt gctacaggtg ttcttgctac tgctgctacc
    46561 gttgcaggtg cagtatttgc tgttaaaaag actattattg accctgagga agaaaaagca
    46621 gcatttgtag aggaaaatcg taaaaaagca gcacgtcgtc gtgttgctcg ctaatcacta
    46681 atagatgaaa gattcgacag gctttatcaa tagcctgtcg aattttttat gctgtgagac
    46741 caagcttttt gcttagacac ataaaagaaa cagctcgtca gcgccgcata ctgcctactt
    46801 cattgaccaa caaacagggc aaactaaggc taattttcac tgatatgaca tgtttcgact
    46861 ataaagcggt tttgtgattg attgatcaca atatcaaatt gctggtgata agggtgcaga
    46921 taacgagcat attgagcgcg cctattgaca tgatgaactc cggattgcga cctctaacgc
    46981 tagtatctct accaagccgc ctttggagct ctgtgtcacc atctgtataa aagtaaagcg
    47041 ataagtcaaa caactctggc tctaaaaagg ttgtcgacat gccttcagca ataaggatgg
    47101 gcacattccc cttcaccaaa aaagagggag accaaggggt atcaatactc aaaaaatcca
    47161 gtccttgctt aaacatcatg atgtcacgcc tcagactggc caattcgtgc ctagcagggt
    47221 gacaggctgt tatactacca agtacctcct ctccctgatc agggtagcta atcaaaacag
    47281 cctgactaaa atcattagcg atgatatagg catctgtttc taacaattgg ctttgtccat
    47341 caggcaaaag ctgctgtaag cgcttagcaa aggttgattt accagatgca ccatgaccac
    47401 taattctaat aagcattttc tcacgattgg ctgctgcagt tacaatagct tgaagtagct
    47461 tctccattat ctctcctcat caaataacat tctaataata ggacatcatt ctacatcgaa
    47521 aaacaagccg gtctcccgaa acagcctgac tgacagtaaa aaaagattga agggcaatcc
    47581 aataaggaaa gcttctccaa tctgattaat agtctataat ggcttaatat gagtgccaaa
    47641 tgtcttggtt atattgttca atcgtacggt ccgatgaaaa gaagccagcc ttagcaatat
    47701 tatgcacaac ctttgtcagc cataggtcct gattgtcata atcagccagc atttgttctt
    47761 tgactgcaat gtattcctca aggtcaatca aggtcataaa ccagtcctta gagattaact
    47821 ccttatagag acggtcaaga cgttcctcat taccaagctc taataattct ggactgataa
    47881 taaagttaac tgcttccttg atagctgggt gggcatcata atagtcttta gacacataac
    47941 cacctgtggc ataaagatca ataatggtat ctgaatcctt accaaaggtg tagatattat
    48001 ccataccagc aagctcagcg atttccacat tagccccgtc catagtacca agcgtcaagg
    48061 caccattgag catgaatttc atattaccag tacctgaagc ttcctttgaa gctagagaaa
    48121 tttgctctga aatatcagtt gcaggaatca aatgctctgc tactgtcaca ttgtaatttt
    48181 caacaaggtg aacattaagg tatggactta cctccggatc gttattgata agctctgaca
    48241 agcaaagaat caaatgaata atatcctgtg caatgatata agccggtgca gccttaccac
    48301 caaagataac tgttatttta cgcttcggca ggttgccttt tttgatctct aagtatttat
    48361 gaatcacata aagggcattc atctgctggc gcttatattc gtggaagcgt ttaatttggg
    48421 tatcaatgat tgaatgctca tcaagctcaa ttcccttatt atccttgagg tagcgcttta
    48481 aggctacttt attatggtgc ttaatttcag ccaatcttgc atgaacagct tgatcctcag
    48541 caaaggccat taatttttca agccttgtcg catcagtcaa gtaagcatca ccgataagct
    48601 ctttaatata gtccgccaac tcttggttgg cgaattctag ccaacgacgg aaggtaatac
    48661 cattggtttt gttgttgaat ttttctggat acagctcata gaaggccttc aattcgctat
    48721 ttttcaggat ttcagtgtga agggcagcaa cgccgttgac acttgtggca aaatgaatat
    48781 ccatatgtgc catatgcacg cgacctgttt catcaatgat ttggacagct ggatctgata
    48841 cccttgcacg aacaagagca tctaattgct cgataatcgt taccagctgc ggcacaacct
    48901 cattaaggaa gtcaagaggc catttttcca aggcttctgc aaggatcgtg tgattggtgt
    48961 aaccaaccat cttttgaacc actgaaacag cctcatcaaa atcaaagcca tgcttttgtg
    49021 tcaatagacg aatcaattct ggaatgacca ttgatggatg ggtatcattg atctgcacgt
    49081 atgcgtaatc agctaagtca tgcaggtttg agccacgctc aagcgcttca tcgatcaaga
    49141 gctgagcggc attagatacc atgaaatatt gctggtaaat gcgaaggagc tcaccatttt
    49201 tatcagaatc atcagggtaa aggaacaggg tcaggttttt ggcaatgtca gtcttatcaa
    49261 atgaaatgcc atctttaatc aagccataat caaccccttc aatatcaaaa aggttaagat
    49321 agttcttggt gtcacgctta tagcccaaaa catcaatacg gtctaagcga gatttcaggg
    49381 taaagttttt aaagggaaca tcatatgaaa tgtcagtcgg tactagccaa gagtcatcct
    49441 ctatccaaaa attaggctct gctgtttgtt cattgtgtct aaagacctgc ttgaacaagc
    49501 cacaatgata attcaagcca accccttcac cattaatgcc aaggcttgag atagaatcaa
    49561 taaagcaaga agccaaacga ccaagaccac cattaccaag cgatggctcc aattcaacgt
    49621 cctctacctc agcaattgat ttgcccgcag cagccagctc ctctttgatg tccttataaa
    49681 tacctagatt aatgagatta ttagaaagca acttaccaat caaaaattct gctgagatgt
    49741 aataaacctt acgtttagct gtgttttttg cttttttgct tgcttcttct ttgagatagg
    49801 aaagcaacga aagatagatt tcctcgttgc ttgcacttgc aagagatttt cctaatgtca
    49861 tttcagtata atctgtaaag cgtttcatga tatcctcttt tcaatatagt attctagtga
    49921 tgattattgg ctcgaccgta tagctcagtc aaatggatta aataggcctt gtgctctgct
    49981 ttaatatcgt cctcaagcat gcgccactgc cagttgccac cgacagtgtt tggcatattc
    50041 atgcggctat cagctgactt atccagcaaa tcctgcatac acaggatagc agtatcacac
    50101 acagtcgcaa agattgttct tagcatggcc ttggtgatgc tttcagcagc tgccttatgg
    50161 atataatgat taacaaactc aacctgctct gcgctcaagt gctcatacca gccattcacc
    50221 acctcattgt catgcgtacc agtgtagaca atgcaattgt gatcatagtt atgcggcaaa
    50281 tcaaagcttt gacttgtcac atcaaacaaa ccaaactcta aaatcttcat gcccggaaag
    50341 ccagtagatg ccagcagctg ctcagccttt tcatcaatgt agccaaggtt ttctgcgata
    50401 attggcagct cacccaaggc ctctcgaaca gctttaaata gagcaatacc aggagctgac
    50461 tcccaatgac catttttagc agtcacatca ccaccaggaa tttcccaaaa atctgagaag
    50521 cccttgaaat ggtcaattct aagcttatcg tacagcttga agctctcttt gatccgatgg
    50581 atccaccaag caaagcctgt ttgctcatgg ctctcccagt tgtaaatagg attgccccaa
    50641 agctgcccgt cctcactaaa gccatcagca ggtacacctg caatgtaaat cggcttttta
    50701 tctgcatcca ccttaaagag ctctggcatc gtccaaacct caacgctatc agcagacacg
    50761 tagattggca tatcaccaat gatagtaatg ccattttgat tagcataggt cttcagcgct
    50821 agccactgct gataaaagaa atattggcag accttatgat aggtgatgcc tttggccaac
    50881 agcttgcggt aatgaagcaa ggcagcctct tcacgcttaa caattgctct atcgtcccat
    50941 tcctggaggg ccttgtgatc aaaatgctct ttaatagcca taaattcagc aaaatcattt
    51001 agccagctcg cagttgcttc aaattcggcg agctgtctta agccttcctc agttgagaca
    51061 aaagcctgaa ctgctttttc taataaaggg cgtctggctt gaaagacttg agcgtaatca
    51121 acagactccg gatttgagcc aaaatcaaca gcagcataat cagcttcctg caaataaccg
    51181 tcctttgcca gcaattcaag gtcaataaaa tgcgtatttc ctgcaatagc tgaaaaagat
    51241 tgataaggag aatctccaaa gctagttgtt gttaagggca aaatctgcca ataggtctgc
    51301 ttggtttcct ttaaaaagtc aacaaattca aaggcctctt taccaaagct cccaataccg
    51361 aagcgtcccg gaagcgagct gatatgcatc agaataccac ttgcacgttt agtcattctt
    51421 tttttctcct tgtaaaatct taatgttgaa attataacgc aaccgtttgc gcaagtcaat
    51481 atcttttcaa aaaaaaagag actttttcgg catgctagag ctgctcaagc cttgataata
    51541 atgagggaag cagctaggac aaaaacaaaa aaaggattgg agagacagcc taagcagctg
    51601 ctcttccatc ctcatctcac tcctatttgg cattaatatc cctgacactc tctcgctttt
    51661 tgaggctaaa gggaaccaaa attttctgac tcagggtttg ttcattggca ttgataatgt
    51721 ctaagagctg cctaaaggag gttcttccca aattttcaac gttaatatca aatgttgtta
    51781 agtaagggtg aatcaatttc gaatagctag aattattaaa ggtaataatc gaaatatcat
    51841 ctggcacctt aatgtcataa aaggacaaga gctggaccat tcgcaccgac aaaacatcac
    51901 caatcacgat taaggctgtg gccttaaagc tacgtatcgt ttcaataacc ttttcgatgc
    51961 ttattggatc ctttcgatca aataacagca tcggtttgtt ttccaaggat aatttcaagc
    52021 agcccttgag atagccaata tagcgctcag aagctacctc tgcctccata tcgtctgtga
    52081 taaacaggat ctgtcggtga cccttttgat agagatgatc aactgcggtt ttagccatta
    52141 gctggttgtc attgtcaata taggtgattt tgttctcatc accttctggt gcgccaacaa
    52201 tgacaaaagg aatctggttg gtcatcaaat agcctctaac aggatcttct tgctcagaat
    52261 ataatataat aaagccatca acacgctttt gcaggtgcat taacttaacc tggctcaata
    52321 aatcctcaac agacatacct gttgcaatgg aaacagtgaa atgatgtttc ttagcttcat
    52381 tggtaatggt cgatagaatt tccataaaaa agggatcact caaacgatca ttagtgataa
    52441 tcggcggaaa aaccaggcca atattatgtg tcaggccact agcaagcatt tgcgcagcta
    52501 cattcggaac atagccaagc tcgctcatag ctcttctaac cttttccttt gtcttttggg
    52561 agatagatcg attatccttg aggacacgac tgacggtcga aggattaaca cctgctttta
    52621 aggcaacgtc ttttattgta accatataaa cctcatttaa tacctgataa tgacgctatg
    52681 tcaggctttt tcacatgtat tttgctttta ttatacaatt atctcctaaa aaatcaactc
    52741 tcgccctgca agaaggcgac ataaaaaact gctgtcctca tgatcgaaaa aatgttaaaa
    52801 aaatcaactt tttttaaaaa aagactagac tttttctgta aacggttgca taatattaag
    52861 tgtaagaaat atatcttagg aggaaatcgc tatgaaatca tggcaaaaag ttatcgtcag
    52921 tggggcaagc ttgacacttg ctagcgcctt attagtaggg tgtgcatctg gttcaaagga
    52981 caaaacagaa actgcatcag gtactgattc aaaaacaatt aagctttggg taccaacagg
    53041 agctaaaaag tcatacacag atgttgtcgc taaatttgaa aaggactctg gctacaaggt
    53101 taaggtgatc gagtcagagg atccaaaagc acaagaaaaa atcaaaaaag atgcttctac
    53161 tgctgccgat gtcttttcac ttcctcatga ccagcttggt cagctcgtag aatctggcat
    53221 tatccaagaa gtcccagagg aatacactaa agagatcgct gatacagcaa ctgatcaagc
    53281 tatccttggt gctcaataca agggtaaaac ctatgccttc ccatttggta ttgagtcaca
    53341 ggttctcttc tacaacaaaa ctaagctagc tgctgatgat gttgcttcat acgataccat
    53401 cacgtctaag gctaccttcg gtggtacctt caagcaggct aatgcttatg ctactggtcc
    53461 attgttcatg tctgttggta acacattatt tggtgaaagc ggtgaagaca ctaaaggaac
    53521 taactggggc aatgaaaaag gggttgctgt tcttaaatgg atttcagacc aagcctcaaa
    53581 caaaggattt gttaacttag atgccaacaa cgtcatgtct cagtttggag acggttcagt
    53641 tgcttcattt gaatcaggtc cttgggatta cgaggcagca caaaaggcta tcggtaaaga
    53701 aaaccttggt gttgctgttt atccaaaggt aactatcggt ggcgaaaccg ttcaacaaaa
    53761 ggccttcttg ggagtgaagc tctatgcggt taaccaagct cctgctaagg gagataccaa
    53821 gcgtatcgca gccagctaca agcttgcttc atacctaaca aatgctgaaa gccaagaaaa
    53881 ccaattcaag acacgtaaca tcgtaccagc taacaagacc gttcaagctt cagaggctgt
    53941 tcaatcaaac gagcttgcaa aaacagttat cacaatggga tcttcttcag attatactgt
    54001 tgttatgcct aagcttagtc aaatgggtac cttctggact gaaagtgctg caatccttag
    54061 cgatgccttc aatggtaaaa tcaaagaagg tgactacctt gctaagctac agcagtttga
    54121 caaggacatt gcagcaacaa aataagctat ctcatttata atactatcct aaacaagtac
    54181 agaggtgggc tattttaacg ctatcctttc tactcatctc taaaggggtg gaactaagca
    54241 tcattatttt ttcagggctt agtccactcc tacttgtttt tgatatgacg taaagcttgg
    54301 tgctacttaa atttttaatc gcttaaagat ttaggtaaca cttagctatg tggtcgttag
    54361 caccaaacgc ttatgaccac agcatctgaa caagagagtc aggtaatcct actttcttgt
    54421 atcctaacat aaaggagaac atatatgact caggcaggct tagcatctca ggttactgta
    54481 aaagaggctt taacaaaggg aagcttcgat attaaactat ccgctatcat catgggcttt
    54541 gccaattttg ctaataaaca attcgtcaaa ggaacactct ttttattgag tgaggtggtc
    54601 tttttcatcg cctttgtttc acaaatcatt cctgctattg gcggcctcat taccctagga
    54661 acacaaacac agggcatgac aaccaaaact atcgacggta tcagcattca ggttgctgtt
    54721 gatggagaca attcgatgct aatgctgatt tttggcttag cctctctgat tttttgtttg
    54781 ttatttgcct atatttattg gtgtaaccta aaaagcgccc gtcacctcta catgctaaag
    54841 caagaagggg caaaaatccc aagctttaag gaggattttg ttagtctagc aaatggtcgt
    54901 ttccatatga ccttgatgac aattccattg attggtgtgc ttctgtttac ggtacttcct
    54961 ttgatctaca tgatttgctt agcatttact aactttgatc acaatcacct cccgccaaag
    55021 tcactttttg attgggttgg tctttccaat tttggtaacg tgttaagtgg tcgtatggca
    55081 ggaaccttct ttcctgtttt ctcatggaca ctgatttggg ctgtctttgc cacagtgact
    55141 aacttcttct ttggtatcat tttagcactc ttgattaata ccaaaggctt aaaattgaaa
    55201 aaaatgtggc ggaccttctt tgtgattacc atcgcagttc ctcagtttat ttcactgctg
    55261 attatgcgaa atctgctaaa tgaccaaggt cccttaaatg ccctgcttag caaattaggg
    55321 ttaatccacc attctctacc gtttttatct gatccaattt gggctaaatt ctctattatt
    55381 tttgttaata tgtggatcgg tattccattt accatgttaa tcgcaacagg tatcattatg
    55441 aacctgccaa gcgaacaaat tgaggctgca gagattgatg gggcaagtaa attccaggtc
    55501 ttcaaatcaa tcaccttccc tcaaatcctc attatcatga caccaaacct gattcagcaa
    55561 tttattggaa acatcaataa cttcaatgtg atctatctct taactggtgg tgggccaacc
    55621 aattcagcct attaccaagc tggaaccacc gatctattgg tgacttggct ctataaattg
    55681 actgttacag cagcagatta taatctagcc tctgttattg gtatcttaat ctttaccgta
    55741 tcagcaatct ttagcttact ggcttacaca agaactgcat catacaagga aggagcagcg
    55801 aaataatgaa aaacaaacgt cgatttcagc ttggattagt ttacgccatt ttaaccgttc
    55861 tctcaatcat ttggctttta cctatcgctt gggttgttct gactagcttt cgtgctgaag
    55921 gcactgctta tgtcgattat tttcttccca agcacctcac attagaccat tatattaagc
    55981 tctttacaaa tgaaacattt ccttttggga gatggtttgt caataccttt gttgttgcta
    56041 tctttacctg tatcatctca acctttatta cagtggcgat ggcttactcg cttagtcgga
    56101 tcaaattcaa gtttcgcaat cgtttcttaa agcttgcact agtgctaaac atgtttccag
    56161 gctttatgag catgattgct atctactata tcctaaaagc acttggcctt acgcaaagtc
    56221 ttaccgccct agtccttgtt tattctgccg gtgctgcact tggattttac attgctaagg
    56281 gcttctttga taccattcct tattcgcttg acgaatctgc catgattgat ggggctactc
    56341 gtatggatat tttctttaag attaccctac cgctatcaaa gccaatcatt gtttacactg
    56401 cactccttgc ctttatggga ccttgggttg actttatctt tgcccaagtg attttaggag
    56461 atgcaaccag cagatatacg gtagctatcg gactcttttc aatgctgcag cctgacacca
    56521 tcaatgactg gttcatggcc tttaccgctg gatctgtgtt aattgctatt ccaatcacat
    56581 tgctctttat gtttatgcaa aaatactatg tagagggcgt tacaggtggt tctgtcaaat
    56641 agcagtaatg atcacgataa cccttactca aaaaatcctt ccc
//
LOCUS       DARYNN010000006        53540 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.006, whole genome shotgun sequence.
ACCESSION   DARYNN010000006 DARYNN010000000
VERSION     DARYNN010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 53540)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53540)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53540
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.006"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            127..2313
                     /locus_tag="TVB59_000313"
     CDS             127..2313
                     /locus_tag="TVB59_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HEL1009257.1"
                     /translation="MKNFKTFITSFINTRLGFVLTLLFCFWIKTLWAYHADFSLDLGN
                     AYQVFLTIINPIPLALLLLGFTLYIKNTRAFYISSWIVYIILNLLLISNSIYYREFSD
                     FITVSAMLASSKVSAGLGDSALNLLRIWDIVYVLDFIILISLSVTKTIKKDPRPFNKR
                     ASFAVTALSCLLLSVNLFLAEIDRPELLTRGFSNTYIVRALGLPAFTIYSGNQTYQAQ
                     KERNGATAEELVDVKQYVKNHYAAPDPQYFGIGKGKNVIVIHLESFQQFLIDYKLKDD
                     DKDYEVTPFINSLYHSNATLAFSNFFHQVKAGKTSDAETMMENSLFGLNSGSFMVNYG
                     GENTQFATPSILAQNGGYTSAVFHGNVGTFWNRNNAYKQWGYHYFFDSSYFSKQTDKN
                     SFQYGLNDKYMFRDSIKYLEQLQQPFYTKFITVSNHYPYTSLRGESSEEGFPLAKTDD
                     ETINGYFATANYLDSALKSFFDYLKATGLYDNSIFVLYGDHYGISNSRNVSLAELLGK
                     DPETWSEYDNAMLQRVPYMIHIPGYTNGGIKETFGGEIDSLPTLLHILGIDTSKMVQL
                     GQDLLSPQNSQMVAQRTSGTYITPDYTSYSGRLYNTQTGLEITNPDEMTMAKVKEIRA
                     AVAQQLAASDAIQTGDLLRFDTDNGLKPVDPTTFIYTKQLKQLKEISEKLGSHSTSIY
                     SKNGNKSTQKLFKAPSYLELNPKEAEKPESTSSSDPKEESVKEQSQ"
     gene            complement(2425..3144)
                     /locus_tag="TVB59_000314"
     CDS             complement(2425..3144)
                     /locus_tag="TVB59_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1009258.1"
                     /translation="MPRFSKAFQYMGATTMLGLSLLAANVNANTNADTVTVDLTYTAY
                     SNLTNEQKAGIQKGTPNEVPIQDKLHYVLVYDKSCGVTASPKGMMSTPKANAKVLPKT
                     GGAADGLVGLAVGLGLLSVSGYLIYKNRKSGSYVLIALLVAGGATTAVSAVDVVRHLN
                     DIVTKTTVKGVSFTYTPEEKVDDYCYVGYIVTQENSPAPTPEPKPDPVPTPEPKPEPK
                     LDPVPTPEPTPDPEYFEAIPQ"
     gene            complement(3750..4109)
                     /gene="rplT"
                     /locus_tag="TVB59_000315"
     CDS             complement(3750..4109)
                     /gene="rplT"
                     /locus_tag="TVB59_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEL1009259.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AAAFTALADAAKAKLGK"
     gene            complement(4170..4367)
                     /gene="rpmI"
                     /locus_tag="TVB59_000316"
     CDS             complement(4170..4367)
                     /gene="rpmI"
                     /locus_tag="TVB59_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEL1009260.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAFTSHRFHGKTKKQRRHL
                     RKAGMVHAGDFKRIKAMVTGL"
     gene            complement(4407..4937)
                     /gene="infC"
                     /locus_tag="TVB59_000317"
     CDS             complement(4407..4937)
                     /gene="infC"
                     /locus_tag="TVB59_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEL1009261.1"
                     /translation="MKIIAKKDLFINDEIRVREVRLVGLEGEQLGIKPLSEAQSLADA
                     ANVDLVLIQPQAVPPVAKLMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPVIDKGD
                     FETKLRNGRKFLEKGNKVKVSIRFKGRMITHKEIGAKVLADFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPISDKK"
     misc_feature    complement(4952..5074)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            complement(5098..5778)
                     /locus_tag="TVB59_000318"
     CDS             complement(5098..5778)
                     /locus_tag="TVB59_000318"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEL1009262.1"
                     /translation="MKAIRIAIDGPASSGKSTVAKIIAKNLGYTYLDTGAMYRSATYI
                     ALKNGYHKEDVNLILQELAKRPISFKKAADGSQLVFLGDQDVTMAIRQNDVTNNVSWV
                     SALPEIREELVNQQRRIARTGAIIMDGRDIGTVVLPDAELKIFLIASVEERAQRRYQE
                     NIEKGIAADFDTLKAEIAARDYKDSHRQVSPLKAADDAIIFDTTGITISAVVQFIQEK
                     AEKIIDMA"
     gene            complement(5793..6290)
                     /locus_tag="TVB59_000319"
     CDS             complement(5793..6290)
                     /locus_tag="TVB59_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEL1009263.1"
                     /translation="MAKEPWEEKIVDDNKATRTRKSRGALISTPWLTALLSVFFVIIV
                     AILFIFFYTSNSGSNKQNETTGFYGASTQKKTTKKVSSKPKTKPKASSNSSAASDTTS
                     PSKTETAPSTEAAGKTITVLAGEGATSIAARAGISVEQLQALNPDHMTQGYWYANPGD
                     EVNIK"
     gene            6339..6536
                     /locus_tag="TVB59_000320"
     CDS             6339..6536
                     /locus_tag="TVB59_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEL1009264.1"
                     /translation="MKVSILPEKCIACGLCQTYSALFDYHDDGIVKLAQSDESSQLID
                     PNDHDAILAVKSCPTKALTLE"
     gene            complement(6523..7011)
                     /locus_tag="TVB59_000321"
     CDS             complement(6523..7011)
                     /locus_tag="TVB59_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HEL1009265.1"
                     /translation="MIKLFGKVRYHWQPELSWSIIYWSIAVAPIFIGLSLLYERTEIP
                     SRVFVLFALFAILVGLGLHRYFVIENNGVLKIVSLKLFAPHRLMIASITKIEVTKSTV
                     CLFVGDKSYLFYMRKWPKKYFLDDLAINPYFKGEVILLDNFIKLDYFEAYQYEKKPLT
                     RG"
     gene            complement(7056..8279)
                     /gene="pepT"
                     /locus_tag="TVB59_000322"
     CDS             complement(7056..8279)
                     /gene="pepT"
                     /locus_tag="TVB59_000322"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEL1009266.1"
                     /translation="MTYETLLERFLNYVKINTRSNPASTTTPSTKSQADFALTVLKPE
                     MEAIGLQDIHYNPANGYLIGSLPANSSKLTRKIGFIAHMDTADFNAEGVAPQIIESYQ
                     GGEIKLGQSGYSLCPEDFPNLNQYLGQTLITTDGTTLLGADDKSGIAEIMTAIEFLVA
                     NPQIEHCDIKVAFGPDEEIGVGADKFDVNAFDVDFAYTIDGGPLGELQYETFSAAALE
                     LKVLGRNVHPGTAKNQMINALQLAMDFHSQLPVDDRPEKTDGYQGFYHLHSMSGTVEE
                     AQASYIIRDFEDSSFEARKAFVTQLAEEMNSQLGAERVFVTVTDQYYNMKKVIEKDMT
                     PVNLAKAVMEDLAIKPVIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEFVSLQT
                     MEKAVDVILGIVQKA"
     gene            complement(8449..9468)
                     /gene="galE"
                     /locus_tag="TVB59_000323"
     CDS             complement(8449..9468)
                     /gene="galE"
                     /locus_tag="TVB59_000323"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEL1009267.1"
                     /translation="MLGSILVTGGAGYIGSHTCVELLAAGYDVVVVDNLCNSNPKSLA
                     AVASIAGREVTFYQGDIRDQQLLTDIFSKHPIVSVIHFAGLKAVGESSRIPLDYYDNN
                     ISGTLTLLKVMTAFNCKKIIFSSSATVYGDPHTVPILETFPLSVTNPYGRTKLMLEEI
                     FKDLYASDNEWHIVLLRYFNPIGAHESGDLGEDPKGIPNNLLPYVSQVAVGKLDCVGV
                     FGDDYETKDGTGVRDYIHVVDLAKGHVAALAKFAEEPSLSIYNLGTGTGYSVLDIIEA
                     FSQVVGRSIPYKILPRRQGDIAACYADASKAKKELNWTAEYGLERMCTDTWRWQSKHP
                     NGYED"
     gene            complement(9536..11905)
                     /locus_tag="TVB59_000324"
     CDS             complement(9536..11905)
                     /locus_tag="TVB59_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HEL1009268.1"
                     /translation="MLDMILFSLSSLYLSIFAVSKNTLNKGAYGSWLVLVLIAGMACL
                     LIKHASSKLLIVSVAVSSYYAVANSYITLAINKNNSRFTISNRTIQEMLLSLAALVSL
                     LILGVLLKKYLFKKDYQSNRGIQVILLSQAFSVLTLNSSLFKTVIKQNDYWPLDSQSN
                     LVSLNLFKYSFCSYMLTFVVYYLIVTAFIEVLSKRWGLRLALVTSLFLGIIFNYFIQA
                     GITAYGDFHGAVIIPGATLFQVLVLTLFFVLVFLLINNYIIALFVNTVIGALISIVNI
                     EKYKQRSEPLLFSDLKWIKEIKFFLNYISLTQIISIILILVLSGLLIYVLYKRYFREK
                     ILSALYLRLMSIGSILLVFASILFVFSQNKDGEIKKGIPVLSSVYNVFDIDWYGLTTN
                     ARFQSLSFVWFKQVTTSTINQPSGYSKSAMQKIYQKYQARAADINKQRHQRISDQTVI
                     YILSESFADPARISGVQLAKDPIAEIHHIMETTTSGLMTSDGYGGGTANMEFQSLFGL
                     PKYNLNPTVSILYSDVFPKLKFSPAISNAFSPKDRIVLHLASANNYSRKIVYNKLGFD
                     TFIATEDSADKPKHLIRMSSSYSDESTYDNILDQLNPKRSQFFSVITMQNHGPWYTEL
                     RDVDVSLAGLDQSETDSLQSYVNLLSITDKSTKAFLSALEKVDKPITVVFYGDHLPGF
                     YPDQVFKNDEEVKYLTDYFIWSNHQTNKLARPRVNSSDFTSLLLEHTDSKVSPYYALL
                     TDVLDTRNSDDSQLTAAQKQVASDLKLLEYDLIEGKGYINAYPDFFKMK"
     gene            complement(11985..13148)
                     /locus_tag="TVB59_000325"
     CDS             complement(11985..13148)
                     /locus_tag="TVB59_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEL1009269.1"
                     /translation="MKTIAIFSGFTSPHLGGVERYTEKIAQQLVSLGYRIIIVTSNSH
                     QLSPIERDQAITYYRFPSKQLFKQRYPILDKNDLYHSMLAELMEERIDFVICNTRFYL
                     TSLMGLKLAKRKAIPSIVIEHGGGYVQVGENVKGHQLLDLFAKVYEHVITFFVKAYQP
                     DFYAVSKRSMAWLKTFGIKAKGVIYNSVDSDLYEVFKSKAYLPALQDKVIITFAGRVI
                     KEKGILLLLEAFEQLTYKDRAVLVVAGDGPLLASLRDSYKEDQSIIFTGKLNFAETMS
                     LLSQSDIFVNPSIYAEGLPTAVLEAGMLKCAVLATDRGGVKEVITSPSQGIIIDDTVS
                     DIKRQLDHLIEHKEKRCDLQEAIHQQVLSGFTWEVTVRQLVTEVIASESESNV"
     gene            complement(13162..14646)
                     /locus_tag="TVB59_000326"
     CDS             complement(13162..14646)
                     /locus_tag="TVB59_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2142 domain-containing protein"
                     /protein_id="HEL1009270.1"
                     /translation="MLDTLFDKLQKASKALLVLLGAFLVLLLLYTQSTDLPIKFLAIL
                     VAIAALLIIFLPSNMEYATVLIIVVMGSVSAFISPINDIPDERVHFARALYLSEGNLN
                     LTNDDSKLLVTDDINLMDHNNGKPLRFQLWSRDHTDEAISFKEIRSTNGYYNFAYIPQ
                     VIGLFIGRSLGLTMGLSYLLGRLCNVLAYAILVFVALRLLTAGKQLLAVGSLLPMNIY
                     LAGSYNQDCVSIGLIILTISLFVQMATTEKIPLSKLFWYTLLCSIITFTKLPYILLIL
                     LLLFIPSRQFGAKASRTFLLKLLSILTVLVVTVFWLKVYGQIKSPQVDMADFLQKVNA
                     KEQLLTVLRNPIVYGFMLLRHTLAHILNPSGIYMFGPLSYGMVELMPISMVYYFAVVI
                     TNANKLQLPTLSRFGMGLMSLGIIGGITFSLYLTFTPVGDLNVLGVQDRYFLGVIPLV
                     LVLLASNNKYLEKAQGLLSNKQVLIGSLLLILGMITRTMLQYYT"
     gene            complement(14650..15891)
                     /locus_tag="TVB59_000327"
     CDS             complement(14650..15891)
                     /locus_tag="TVB59_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HEL1009271.1"
                     /translation="MKTSSRIQSDQSIFIWNVLGTSSTALISVILLMIVSRVLSKSAS
                     DTFSFAYAIGNQLITIGLFQIRNFQSTDILHKYRFKDYFYTRLVTCFLMIAISVLYIY
                     LGSYSGFKGLVIWLICLYRCTDAISDVFQGMFQQRERLDIAGKSLFYRNMLVILGFTL
                     CLVLTKQLVLSLIVICLISVACIVLFDITPSVSFTSLERRIDAQSILGLLKESFPLFL
                     NGFLLIYIYNQPKFVLEQLYSKQLIPAGVQTEFNILFMPIFMINLIFLFLRPMITQLA
                     IYHSKEDKKSFAQLERRLSLVLLLASLAILLASYFVGLPVLSLVYGIDLRHYQLDFML
                     LIFGGIISTFATYIDNLITIIRKQHLLVIPYVVSFISSLAITGSLARSFGVIGVTYGF
                     IISMMIWLLLSYGLYIMEKRK"
     gene            complement(15875..16231)
                     /locus_tag="TVB59_000328"
     CDS             complement(15875..16231)
                     /locus_tag="TVB59_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2304 domain-containing protein"
                     /protein_id="HEL1009272.1"
                     /translation="MFIGLQLILIIVALLTAMFILDSIRRSKILIEDSFFWLFFSLIV
                     LLLSLFPNAAVYFSRLLGFESPANFVFLSIIFLLIINQFFITQKLSRTEIKLKKMIQY
                     LALNEKEKQEEDENQQ"
     gene            complement(16236..16925)
                     /locus_tag="TVB59_000329"
     CDS             complement(16236..16925)
                     /locus_tag="TVB59_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEL1009273.1"
                     /translation="MKKDLLVMIPAYNEEESIEKVVENIKRHFPQYDYVIINDGSSDR
                     TSEICHHNHYNIIDLPENLGLSGAIQTGFKYAFKKGYAKALQFDADGQHLPEYIEALS
                     DSINAGADCVIGSRFVSAEKNRSLRMIGNSLISFFIKLTTGKRITDPTSGMRMFNQEL
                     IRIFATNINYTPEPDTISYLIRQGYRVSEVQVQMNDRLAGQSYLTLSRSIKYMVHMFI
                     SIILIQNFRKR"
     gene            complement(16955..18700)
                     /locus_tag="TVB59_000330"
     CDS             complement(16955..18700)
                     /locus_tag="TVB59_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-Rha alpha-1,3-L-rhamnosyltransferase"
                     /protein_id="HEL1009274.1"
                     /translation="MKRLLLYVHFNKYHKVSDHVYYQLEQMRALFSKIVFISNSDIHQ
                     EDLEQLEQRHLMDQFIQRHNKGYDFAAWHDGMKALGCEHLVDFDSITIMNDTCFGPLW
                     DMKPYYLKYEADEAVDFWGMTNNRATKAFKEHIQSYFISFKKSLVHSKEFRQFWENIV
                     ELTDVQDVIHNYETRITTVFVEAGFRYKTVFDTTKEDSSSMLHADFSYYNPTAILKHH
                     VPFIKVKAIDANQHIAPYLLDFIDQKTTYPASLIVDHMSQVHPPDAKYLLAHKYLPEQ
                     PISIDQSKKIAVHLHVFYVDLLSEFLEAFSHFHFDYDLLITTDSKAKKAEIKEILRES
                     GASADILVTGNIGRDVLPMLTLKERLSQYDYIGHFHTKKSKEADFWAGQSWRTELIDM
                     MVKPADQILTALAADAIGIVIADIPSFFRFNKIVDAWNEHLIAPEMNQLWQAMGLTKR
                     IDFQTMDTFVMSYGTFVWFKYDALKPLFDLDLSEADIPAEPLSQNSILHAIERLLIYI
                     AWDRHYDFRISRNEKLLTPFIDNKLLNLREGSVPHTYVDFDYMGGIKGALKYIVIGPA
                     KAIRYIIKRLLKRRV"
     gene            complement(18697..19704)
                     /locus_tag="TVB59_000331"
     CDS             complement(18697..19704)
                     /locus_tag="TVB59_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEL1009275.1"
                     /translation="MKKVSIICTNYNKGPWISEALDSFLAQQTSFDVEIIVIDDASTD
                     YSRQILMDYQASFPDRIRLIVNEVNLGIARTWVKACLEAKGQYIARCDGDDYWTDTLK
                     LQKQVDLLDSSPDSKWSNTDFDFVDTDGKLIQSNAFESGFTPLTDTYEKMLALKGMTM
                     SSTWLVEADLMRAVNQRIDLETSDDTFDIQLELFQSTSLAYLKDSTTVYRMTDNSDSR
                     PAAEEKMLGRIQGLLETQLSYLSKYPTANMEAIAKALLKQDAKNEIRIHQLSHTIHQL
                     RQTLADQEALQAEKIDQLQQQLDHQRQEVEALTHQYNCVVTSRRWRYLSKLLELFRRK
                     K"
     gene            complement(19725..20933)
                     /locus_tag="TVB59_000332"
     CDS             complement(19725..20933)
                     /locus_tag="TVB59_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1009276.1"
                     /translation="MANKEIAVTVDHVSKSFKLPTEATKSFRTALVNRFKGIKGYTEQ
                     HVLRDISFDVYKGDFFGIVGRNGSGKSTLLKIISQIYVPEKGQVTVEGKMVSFIELGV
                     GFNPELTGRENVYMNGAMLGFTTEEVDDMYDDIVDFAELHDFMNQKLKNYSSGMQVRL
                     AFSVAIKAQGDVLILDEVLAVGDEAFQRKCNDYFMERKESGKTTILVTHDMGAVKKYC
                     NRAVLIENGLVKAYGEPFDVANQYSVDNTELKNAEQGAAAEPVSDLASQLEVRLTSKP
                     SLSPDEPISFEISYHVLKDEPTYVAFSLTDIDRNIWVYNDNSQDQPTSGPGHKNISYQ
                     CQLSHLNDIKLKLEVTVRDQNGQMLLFLTANHSPLVVLQRNDIAPDDLSALDSASGLY
                     QRNGSWLINQ"
     gene            complement(20933..21736)
                     /locus_tag="TVB59_000333"
     CDS             complement(20933..21736)
                     /locus_tag="TVB59_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1009277.1"
                     /translation="MELLSKKNRILLKELVKTDFKLRYQGSAIGYLWSILKPLMMFTI
                     MYLVFIRFLRTGGDVPHFPVALLLANVIWSFFSEATSMGMVSIVSRGDLLRKLNFSKH
                     TIVFSAVLGALINFSINLLVVLVFAAINGVTLSPHAYLALPLFVELAVLTVGVALMLS
                     TVFVYYRDLAQVWEVLLQAGMYVTPIIYPITFVFDRHPLAAKILMLNPLAQIIQDLRY
                     LLIDRANVTIWQMSTNWCYIIIPYLIPFVLLALGVAVFNKNAKKFAEII"
     gene            complement(21736..22671)
                     /locus_tag="TVB59_000334"
     CDS             complement(21736..22671)
                     /locus_tag="TVB59_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEL1009278.1"
                     /translation="MKINILMSTYNGARFLAEQIQSIQRQTVQDWTLLVRDDGSTDKT
                     LAIIQAFAKKDPRICLINADVQENLGVIRSFHTLLTYEKADIYFFSDQDDVWLDNKLE
                     LTLAEAQKHKISEPLLVYTDLKVVNQDLEVRHESMIQTQSHHANTQLVQELTENTVTG
                     GTMMINHALAEQWVSCEHVVMHDWYLALIAAAQGELVYLDVATELYRQHDANVLGART
                     WSKRLKQWRKPHKLIEKYWWLIVSSQHQARQLLDLQLNPADRRLIEAYVGLLDRPFYQ
                     RLSDFKAYGFRKNRAFHTLVFMALIMTKFGYRRKE"
     gene            complement(22661..23815)
                     /locus_tag="TVB59_000335"
     CDS             complement(22661..23815)
                     /locus_tag="TVB59_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1972 domain-containing protein"
                     /protein_id="HEL1009279.1"
                     /translation="MQDVFIIGSRGLPAKYGGFETFVEELVTNQTNKSITYHIACLSD
                     SKHKEHFVYKGADCFYINPPKLGPARVIAYDMMAISHALAYIDRYHIQKPIFYVLGNT
                     IGGFIAPFAKQIHQRGGRLLINPDGLEWKRSKWSKPVQQYLKYAEKQMTKHADLVISD
                     NIGIEAYIKKSYPWAKTTFIAYGTEIGRSCLSTSDEKVRTYFQTFEITENQYYLILGR
                     FVPENNYETAIREFMASSTQRDLVIICNHDKNPYFERLVSATGCDKDARVKFVGTQYD
                     KQLLAYIREHAFAYIHGHEVGGTNPGLLEALAHTQLNLVLGVTFNQSVAKTAALYWTK
                     EKGSLTGLINRVDQKESFADLGERAKQIIAKEYTWEKIVGEYEALFLDED"
     gene            complement(23940..24788)
                     /gene="rfbD"
                     /locus_tag="TVB59_000336"
     CDS             complement(23940..24788)
                     /gene="rfbD"
                     /locus_tag="TVB59_000336"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HEL1009280.1"
                     /translation="MILITGSNGQLGTELRYLLDERSVDYVAVDVAEMDITNATKVEE
                     VFAQVKPSLVYHCAAYTAVDAAEEEGKALNEAINVAGTEHIAKACERYGATLVYISTD
                     YVFDGQKPAGQEWLETDTPDPQTAYGRAKRLGELAVERYTKQFYIIRTAWVFGHYGKN
                     FVFTMQNLAKTHSRLTVVNDQHGRPTWTRTLAEFMCHLADNRKPYGYYHLSNDAKEDT
                     TWYDFAREILKETAVEVVPVDSSAFPAKAKRPFNSTMNLDKAKATGFVIPTWQEALEA
                     FYKQQQ"
     gene            complement(24930..25268)
                     /locus_tag="TVB59_000337"
     CDS             complement(24930..25268)
                     /locus_tag="TVB59_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEL1009281.1"
                     /translation="MTETLKYTEEQVAAIKDRILEALGTVIDPELGIDIVNLGLVYEI
                     RFDDNGHTEIDMTLTTMGCPLADLLTDHIHDAMRDVPEVTKVEVKLVWYPVWSVEKMS
                     RYARIALGIR"
     gene            complement(25566..26675)
                     /gene="rpoD"
                     /locus_tag="TVB59_000338"
     CDS             complement(25566..26675)
                     /gene="rpoD"
                     /locus_tag="TVB59_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEL1009282.1"
                     /translation="MAKEKEITTFNVQIAEFIRHHKKEGTATDDEVTEKLVIPFTLDA
                     DQIDDLLERLTDGGISITDKEGNPSSKYVVEEPKPEELTDEELIGSNSAKVNDPVRMY
                     LKEIGVVPLLTSDEEKVLAVAVAAGDMEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMEMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRVVLREQLDEVLDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRHPSRSKQLRDFIED"
     gene            complement(26684..28498)
                     /gene="dnaG"
                     /locus_tag="TVB59_000339"
     CDS             complement(26684..28498)
                     /gene="dnaG"
                     /locus_tag="TVB59_000339"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEL1009283.1"
                     /translation="MGFLWGGDGLAIDKEMISQIKHNVNIVDVIGEVVHLSRAGRHYL
                     GLCPFHKEKTPSFNVIEDRQFFHCFGCGKSGDVFKFIEEYRQVPFLESVQIVADKAGM
                     AVTVAPSQTSLSQKQHPHQALIDLHEDAAKFYHAVLMTTKIGQRAKEYLYQRGLDDQL
                     IEYFRIGLAPNEMDYLYQALSKKYTEAQLTASGLFHVSEQSNAIYDAFRHRIMFPLCD
                     DKGNMIAFSGRIWAREDIEKQQAKYKNSRATVLFNKSYELYHLDKAKPIIAKTHEVFL
                     MEGFMDVIAAYRAGYGNTVASMGTALTPEHVRHLKQLTQKVVLTYDGDDAGQNAIAKS
                     LELLADFQVEIVKIPNRMDPDEFVQQHSPEALAELLQHSRISSVEFLIDHLKPENMDN
                     LQSQIAYVEHISQIIAQAPSITAQNSYINKVADLLPDFDYFQVEQSVNALRLQDRQSL
                     QQGQASQPKASLVTLPINKSMTALAKTESHLLHRLLHHDYLLNEFRHRPDFYFDTPAL
                     QTLYEQLKATGQITSYDLSQLSEEVNQAYYRVLEENLPDEIASGEIEDILSRQMTLLK
                     QRELHRQGKQIRESSSKGDHQMALEALERFIAEKRKME"
     gene            28745..29119
                     /gene="mscL"
                     /locus_tag="TVB59_000340"
     CDS             28745..29119
                     /gene="mscL"
                     /locus_tag="TVB59_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEL1009284.1"
                     /translation="MLKELKAFLFRGNIIDLAVAVIVGSAFSAIVTSFVNDIITPLIL
                     NPALKAANVENIAQLAWNGIKYGSFLSAIINFLIVGTSLFFVVKVAQKAMPKKGEEEP
                     AKPKTPTQEELLLDIRDLLAKK"
     gene            complement(29345..29521)
                     /locus_tag="TVB59_000341"
     CDS             complement(29345..29521)
                     /locus_tag="TVB59_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEL1009285.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVTKAGTLQESRKREFYEKPSVK
                     RKRKSEAARKRKKF"
     gene            complement(29676..30488)
                     /locus_tag="TVB59_000342"
     CDS             complement(29676..30488)
                     /locus_tag="TVB59_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEL1009286.1"
                     /translation="MNMKRLLVGALAMVSVFALAACGQANKTSLQDRIQEKGKLVVAV
                     SPDYAPFEFKALVDGKDTIVGADIELAQAIADELGVKLELSAMNFDNVLSSLQTGKVD
                     IAISGLSYTKERAKVYDFSEAYYETENAILVKASDAKHYANKDSLVGKKVAVQKGSIE
                     EGLVKEQLNKANCVSLTVMGEAINELKSGQVQAVDLEAPVAAGFLAQHKDLALAPFKL
                     QASDGDAKAVAMPKGSDDLRQTINKVIKQLNKDGKYKAFIQEAALLTGNAVE"
     gene            complement(30556..31671)
                     /locus_tag="TVB59_000343"
     CDS             complement(30556..31671)
                     /locus_tag="TVB59_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HEL1009287.1"
                     /translation="MKLPVFGVEEWLNQHEKRAVYDIAGSSIASLTLEELFDLTQEQP
                     QAFYQQLHQKPLDYGWIEGSPDFKQAVAGLYQQQKARNILQTNGATGANFLVIYALLE
                     AGDHVIAHYPSYQQLYDIPASLGVEVDYWQIREEQAWLPDLNELGAMIRPNTKMIMIN
                     NANNPTGAYMTKPYLEELINIAREHDIYLLSDEVYHSFTSDHLLAVADLYDKGITVNS
                     MSKTFSIPGIRVGWVAASETICDQLRLYRDYTMICAGVFDDMVASLALKHADKLLQRN
                     QAIIRTNLAILEDWITGEARASYHRPNEVSTAFVRLDIDEDMEAFALRLLEDYGTLVV
                     PGNRFNQANHVRIGYCCQPQVLQAGLSRLSQCLKNIQ"
     gene            complement(31941..35582)
                     /gene="addA"
                     /locus_tag="TVB59_000344"
     CDS             complement(31941..35582)
                     /gene="addA"
                     /locus_tag="TVB59_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEL1009288.1"
                     /translation="MRIDEGFLTPEAIARLQQEEALSDKTHKRTAQQIEAIYSSGQNI
                     LVSASAGSGKTFVMVERILDKILRGIPVDCLFISTFTVKAATELIERIEKKLHTAIAE
                     TQDYQLKAYLNDQLQALSQADIGTMDAFAQKLVHQHGYVLGISPHFRIIQDKAEQDIL
                     KREVFRQVFEDYMSQTDNKAFIQLVQNFSGRRKDSSAFREIVDSIYAFSQSTANPSSW
                     LAEVFLRGSKTYTSFTDIPDQAVDALLACMQDTADQLRDLTDMEGYAQTTKAGKLTAK
                     YTKHLKMIDSLYEWALHFDSLYGKARLGQLAQELTALLPSGADITVAGHKYPIFKSLQ
                     EQLVRFRHLETILAYQQESLPLLEVLQAFVISFSEAYLAAKMQENAFEFSDIAHFAIE
                     ILQQAPDIRQAYQGHYHEVMVDEYQDNNHMQERLLELLSNGHNRFMVGDIKQSIYRFR
                     QADPQIFNQKFKDYQSNPEHGKLILLKENFRSQSEVLNVTNAVFSRLMDESLGEITYD
                     DKHQLVAGSEGQRQPYPNNRAQLLLYDTDQVQEGTEEALANDGISAGEVILVAKEIIR
                     LYNEEKVAFEDITLLVSSRTRNDTIFQVFNQYGIPLVADGGQENYLKSVEVMVMLDTL
                     RSINNPLNDYALVALMRSPMFSFDEDQLARISLQGSSQKQPQAFYDKLSNSLRGQGEH
                     PELIGQELMTKLADFDGTLRDWRQFAKLHSLYELIWKIFNDRFYFDFVASQPKAEQAQ
                     ANLYALAIRADQFEQSGYKGLSRFIGMIDKVLETQNDLADVEVERPKHAVNLMTIHKS
                     KGLEFHYVFILNCDKRFAMADLQAPIILNRDEGIGIKYVANVKELLREEKLASLKVTM
                     ETLPYQLNKQQLRLATLSEQMRLLYVAMTRAEKKVYLIGKASKEKVQEKTADNSSEGR
                     LALASRERLLSFQDWLLAIAATFSKEDLFIDVRFVDDSDLTPEAVGQLRPSGLLQADD
                     LKDNRQTEDIARALDMLDKVSELNASYQAAIELPTVRTPSQLKTLYEPLMDTDGVDII
                     DQPYHRPKTFELPDFSKKKAVEPSQVGSSLHELMQRIPMSDQVTAGDIEQTLQLVSAD
                     AEVKARLDIEKVTSFFATTELGQLLQEHHQRLHREAPFAMLKKDSLSQEQYVVRGIID
                     GYLLFEDRIVLFDYKTDRYQQSAELKQRYQQQMDLYAEALSQSYGIARIEKYLVLMGG
                     SQLEVVRLA"
     gene            complement(35572..38793)
                     /gene="rexB"
                     /locus_tag="TVB59_000345"
     CDS             complement(35572..38793)
                     /gene="rexB"
                     /locus_tag="TVB59_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEL1009289.1"
                     /translation="MKLLYTEISYSMTEILVKEARAYADKGYRVFYIAPNSLSFEKER
                     SVLALLPEQGSFAITVTRFEQMARYFTLAKAANRQALDDNGLAMIFYRVLMQLQEDEL
                     KVFHRLRTDQAFIAQLVELYKELQAANLTAFDLTTLDRPEKQEDLITIMTKAEQLIAQ
                     GDYDQSSRLAQLAEAIKSKSLDDELRQTVLVIDGFTRFSAEEEQLLALLNEACEEIVI
                     GAYISQKAYRLAFTKGNLYEASLAFIQQLAQQFQTKPIYTTSEKVFDVSFSRLTQLLE
                     ANHDYSKLDWQLSAKDKSKVVIWQALNQKEELEHVAKAIREKLYQGYRYKDMLVLLGD
                     VASYQLQIGPIFEKFEIPYYIGKQEPMSAHPLVQFVESLERGRRYNWRREDIVNLLKS
                     GLFGRFQEGELDQLEQYLVFADIQGFTKFSRPFTLNSSRQYPLPLLNQLRLAVVTPLQ
                     QLFKSQKQLGASLLDKLMTFFKTIQLADNFEALAGSRRETDREKDEEVWKAFTGILET
                     FYQVFGQEKMTLADCLALIKMGMQTAHYRTVPATLDVVSIKSYDLVEPHSKPFVFAIG
                     LSRSHFPKQTKNTSLISDQERASINEQTASYQRLDVPSFENIKKNHQTALSLFNAATQ
                     ELVLSLPTSLTNSSDDVSPYLKELIALGVPVIEKGKNRLSHSAADIGNYKALLSRLVA
                     INRQGIADDMTSEDRNFWTVALRYLKRRLADEQLSLPAFEHHLTTKPVAPEVIETRFS
                     SQQPLNLSSSALTVFYNNQYKYFLKYVLGLQEPESIHPDARIHGQYLHRIFELVTKDR
                     SNAAFDQKLGAAIAAVNQQSAFQQVYQADAEGRYSLEVLKGIAYSTASVLDLNQGLQI
                     TKQEEAFELALGQQVLIRGVIDRIDQLADGRLGIVDYKSSARVFDIVAFYNGLSPQLV
                     TYLAALKNKGQGLFGAMYLHMQEPRLSLSDFKALDDQLVAAAYKELTYKGIFLAQAKE
                     YLANGSYHLNNTLYETDELETLLAYNEQLYLSAVKQIKTGHFLINPYTADGKSVQGDQ
                     LKAITRFEADLDLGYARRLVVLPTKERRQAFLTRMNEEIKHED"
     gene            complement(39002..40402)
                     /locus_tag="TVB59_000346"
     CDS             complement(39002..40402)
                     /locus_tag="TVB59_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEL1009290.1"
                     /translation="MIVQLLFLVLKYSQYLFLAFLIAYASFLLLSLIVGTIHLYERRQ
                     QAPVGGDVSLPPVSILVPAYNEELTIIETVESLLMLDYDCYEIIVIDDGSTDHTAKLL
                     KEQFHLEAVTCSINQRIPTRPLKAVSQKQLKHIKLTLLEKANGGKGDSLNLGINAAQY
                     DYLLCMDADSMLQEDSLKRIAKTAAKDPSVIAVGGMVKVSQGVALAAGRIVDYHLPRQ
                     LISCAQAIEYDCAFFGARVLLDQAAGNLIISGAFGLFKKELAIAVDGYDTGTLGEDME
                     LVMKLHFFCHNNKIPYRIGYETDAICWSQAPSRLKDLCRQRRRWFLGLYQCLKKYLQF
                     FVSCRFKATVLISYVLYLLFELLSPFIEAFGVIIIVLSLLCHQLNTTFFVSLMLLYIC
                     YCVLIALTSFLNRVYLQNNSSITLFDMAWVIYAAIYQCLVLHTVLTLIKVSSFIGYQR
                     KKNAWGQITRDKHRAA"
     gene            complement(40544..42685)
                     /locus_tag="TVB59_000347"
     CDS             complement(40544..42685)
                     /locus_tag="TVB59_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009291.1"
                     /translation="MKKYLIFVGLLLSVIGLSYYCCDIDGRLYLPVSNQSAIRTVFYT
                     KDKRIYDQKGSPYLIKGVDVESSIAGYRRRDLSVDEKTYYRWFKQIAAMGANTIRVRV
                     IMPVTFYHALRRYNDRASHPLYLLQGFRIDAYHDNSSISALDKAYLGTLLREARASVD
                     VIHGRKRIWHSDLGLQHYDQDMSKWLLGYIVGDDWYSGTIAYTNHQNHAKPVGFKGRY
                     YATTPQANRFEAILAEIMEEITSYESRKYGWQHLVSFSNTPQSDPFVYQDPFASQAAK
                     YVQLTIENIKPSAKVKAGLFASYKLLDCHSAYRDYLLFDRLGLTDRLVGDIKRMPLYQ
                     GYVKLLTSYHRVPVVVTGYGYSTARGVDQMISTSSPLTEKDQGERLMADYTAFIASGC
                     CGATIHSWQDDWTARSWNTSFATNKHQSFLWGDVQSKAQGYGLLTFEHAPRTHAIDGQ
                     KAADEWSRALTYKKNGQQLLVDQDEKYLYIAIESTKKQPLQRQWLIPLDITPKTGSRV
                     IEGFSARFDRFADFALVVDDHKGSRLLVQERYHATDANYLRQINGKDFYVFPPNKHTP
                     RFTMVDMVVRNDGIFAAIDQVPIAKRGLKRYPTGQLKQGNGKRGSAHFDSQTDISFGE
                     RLIELRIPWQLLNFSDPASNKIHDDYFEHYGVEELAIEAIAIGFAPLKESKVIAMVEY
                     PLLSWERPRVREVLKTSYQQVQAVWQEKRRR"
     gene            complement(42692..44125)
                     /locus_tag="TVB59_000348"
     CDS             complement(42692..44125)
                     /locus_tag="TVB59_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CotH kinase family protein"
                     /protein_id="HEL1009292.1"
                     /translation="MKEKTIYVIVLVCLLLAAICGIGFPKTSAKRIHHHLQTVKKSSR
                     STGEFSSHLPIISIDTHHQQIPEQREYEGETKRQKTIKTTVSLRDQLDREHSLSESPR
                     LSLTALIAYRGNSSRHFDKKSLKLRFINKRAKPKAVSLAGMSKESEWVLHGPFLDRTL
                     VRNYLSYNIAGEIMTYAPNVRYCELVVDHQYCGLYLAVESIEQGRHRVNIEKSDRKSD
                     KTPYILVWDRRHKAKQALDHYVSYTNQAGLSSLDIKYPSLHRLTPKQKQFIEKDISHI
                     EKLLYSYDLKQYTDYLDQESFADYFIINEFFRNIDAGKFSTYLYKDLRDKLKLVVWDF
                     NNAFDNQIEAPYDEADFTLSDAPWFCMLLKDPSFVKLVVTRYHQLRQNVLSTDYLIKY
                     IDATVAFLGPAIQRNYHKWGYVFTVPSRSDATNYLVPASRNYSSYEASVKQLKDFIRR
                     RGRWLDKHIETLYQYSAPSKNTNTLLE"
     gene            complement(44131..44808)
                     /locus_tag="TVB59_000349"
     CDS             complement(44131..44808)
                     /locus_tag="TVB59_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4956 domain-containing protein"
                     /protein_id="HEL1009293.1"
                     /translation="MKQLLRHVFEQRGTLSFQDVLLHIVAAALLSIVIYMSYAYTHTG
                     TAYSKKFNVSLMTLTVLTATVMTVIGNNVALSLGMVGALSVVRFRTAIKDSRDTVYIF
                     WTIVVGICCGVGDYTVAATGSSVIFMLLLLMGAVRNDNRLLLIVRCDKQMEIELERLV
                     FNYFSGKAIQSVKNTTSDDIEMIFELSRKDYDSTYQQANPLTEAVYQLGRVDYFNIVS
                     QSDDITG"
     gene            complement(44822..45517)
                     /locus_tag="TVB59_000350"
     CDS             complement(44822..45517)
                     /locus_tag="TVB59_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001006716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate polymerase domain-containing
                     protein"
                     /protein_id="HEL1009294.1"
                     /translation="MNEVLRQEKKYLITIEDYYRLSHEFSKLLRLDAHSSSEGYVIRS
                     LYFDSLEDVDWQEKEDGIELRRKIRLRNYGSQSSFAKLEMKQKQGSNQKKRSLRLTRA
                     DAQLLIKGDKSILLTYPDRFAAECYSRMSMQLYQPKTVIEYQRKAFVAKENNIRITFD
                     HHIIGSETNADIFSDHLPQNYLLDPYLVILEVKYNGFLLSYIKKLLESVNGSELSASK
                     YCMGRAISKHYRF"
     gene            complement(45645..46280)
                     /locus_tag="TVB59_000351"
     CDS             complement(45645..46280)
                     /locus_tag="TVB59_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zf-HC2 domain-containing protein"
                     /protein_id="HEL1009295.1"
                     /translation="MKYDCELIQDLLPLYVDDTLSDYSRAVVEAHLTSCKDCQTDLAD
                     LRQDYSKVEEELQEYQAEVCAFSRFIRKQRQQMIVATISICLVTGILSSILTAHRIRA
                     PYDYVAIDVGEHTQLNKEGLLSTARTTAKDHVALVYKHKAQKVNGSFEISELQARKIQ
                     QQLKQAMLKEANATDISSRQLDQSQKRLSCNQDDQLVYIISTDGRIYYFGR"
     gene            complement(46270..46809)
                     /locus_tag="TVB59_000352"
     CDS             complement(46270..46809)
                     /locus_tag="TVB59_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HEL1009296.1"
                     /translation="MVKGVLRGDKLLEFEDIYLEYKDDVYRFVNKLCCYQNSLSDDIT
                     QETFLKAYRNIAKFSGDSSIKTWLFTIAKNTFFTEIKKKKYENMSMESLEIVDAKGHD
                     EPLDKIARRELLEITLTIIFNLPEKMQAVFLARIYSGDSYEKIAKDIGITVSSAKVLV
                     FRARKHIKRQLREEYGYEV"
     gene            complement(47098..50814)
                     /locus_tag="TVB59_000353"
     CDS             complement(47098..50814)
                     /locus_tag="TVB59_000353"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pullulanase"
                     /protein_id="HEL1009297.1"
                     /translation="MMKRLRENQALFEERQLFGIRKLKLGVASVAIATAFSLGTASGQ
                     ITAAAESLTSVEPADGAVMVKSEAADQGSNELPEATDISDIAGISDVTKVSAAVNADT
                     VKEVQPVAVPLVEDQAHEETTDQSQPSSSIVSVTTDSSLETPEATSSEEPIAEQTLRL
                     HFKTLPAQDLSSLGLWVWDDVETPSDQLGGWPTGATNFSLAKTDDYGYYMDVKLSANQ
                     ANKVSFLINNTKGDNLTGDRTIDLLSPKMNEVWIDGQELSYYRPLAQGYIRINYYRSD
                     GHYDNKSLWLWGSADASMTSQQGAWPDGIDFKQVGRYGAYIDVKLADTNELGFLLLDE
                     RQTGDAVKIQPNDYIFKDLKNHTQIFLKDEDPTIYTNPYFVNTVRLIGAQQVSPSSIE
                     ASFTTLADVDKESLLKELKISTDSKEAVAITDITLDEKTHKAVITGDFSQAVATYTVT
                     FHHESFQARPNWQYKDSLYAYDGELGARVREAGAKVDLTIWSPSADKVSLVLYDKADQ
                     TKVIGNLALAKGDKGEWSITLSADSGLGISDYRGYFYHYEITRNGKSVLVLDPYAKSL
                     AAWNSELAKTDPSYKVAKAAIVDPAAIGDKELAFADIKGFHKREDAIIYEAHVRDFTS
                     DQAIANDLKAQFGTFAAFVEKLDYLKELGITHVQLLPVMSYYFVNELANKERMLTYSS
                     SDNNYNWGYDPQSYFALTGMYSTDPTDPAKRIEEFKQLVNEIHKRGMGVILDVVYNHT
                     ANVDIFEDLEPNYYHFMNADGTARTSFGGGRLGTTHYMSRRVLVDSITYLVDEYKVDG
                     FRFDMMGDHDAAAIEKAFLAAKALNPNIIMLGEGWVTYQGDEHMPEQPADQSWMSQTD
                     TVASFSDDFRNQLKSGFPNEGSPAFITGGARDIMTIFHNIKAQPTNFLADDPGDVIQY
                     IAAHDNLTLFDIIAQSIKKDPSVAANAAEIHRRLRLGNLLVLTSQGTPFLHAGQEYGR
                     TKQFKDEAYKGKVADDKVPNKSHLLVNEDGTPFEYPYFIHDSYDSTDAINHFDWAKAT
                     DTERYPESTTSQAFTKGLIALRRSTDAFRLASKAEIDQKVKLITVPNEHGIKAQDLVI
                     AYQTTASNGDVYAVFVNADSNDRTIRLTGEFQALLAGEVIVDAKQAGTEALASPEGVV
                     LTKDGVKLSGLTATIIRLRASQSDKGTLGAMTDQAAHHQEKLVAAQTAGEVSQFSAKT
                     LPKTGTSQLDALLALAGSGILAGLGGLVSKSKRR"
     gene            51294..51839
                     /locus_tag="TVB59_000354"
                     /pseudo
     CDS             51294..51839
                     /locus_tag="TVB59_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003030066.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1595 family transposase"
     gene            51920..52375
                     /locus_tag="TVB59_000355"
     CDS             51920..52375
                     /locus_tag="TVB59_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009298.1"
                     /translation="MVKHAKTNLHFELERSISRKVDSKLIAYQVSLSDGFYDKYTKLW
                     DKTYSFDFVINHRAFYAQLTKRCVYDVLLQTLEKISRKAIAKQLAELEALVDVSESKE
                     DFQIFFEKKYKLSFPDLKNCVYPKKKELSDFDQNLWIALHYNPRKERDT"
     gene            52375..52662
                     /locus_tag="TVB59_000356"
     CDS             52375..52662
                     /locus_tag="TVB59_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009299.1"
                     /translation="MTTWYDYMVRASEHSGSDGDLWFRYLYKVIKDKETKLTTDDVEQ
                     LLKNPNLTPFQKVTLQDALTEGTHTREHVLQANRKSQPKDILKLFREGNYG"
     gene            52655..53203
                     /locus_tag="TVB59_000357"
     CDS             52655..53203
                     /locus_tag="TVB59_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter peripheral membrane
                     component"
                     /protein_id="HEL1009300.1"
                     /translation="MDKKILFKALNTELAKENISLDIICVGGFVLEYYNLRGTQDIDA
                     FYQEGVNIRQMIKKVGDEFGVNEPDELWLNNSVANLNRIPPKTICETVFHYSNLIVLV
                     PPLSYILGMKLESGRDRDRQDAGDIIKLANIRSPKKLINTLEEYDFQPDISMILEVFE
                     IAYGMEWLANYMTEHPEEFRHY"
     gene            complement(53382..>53540)
                     /locus_tag="TVB59_000358"
     CDS             complement(53382..>53540)
                     /locus_tag="TVB59_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1009301.1"
                     /translation="EAQKGDKPAVPKAMEHKLPSTGEATAPFFTAAALAVLASLGVAV
                     VSRKRKKH"
BASE COUNT        15906 a        12204 c        10123 g        15307 t
ORIGIN      
        1 tattaaaaaa tcatactaga tttaaactta ttgcaagcat tagctccata tttttggtat
       61 aatttaatct gagattttat ttggagatta tatcttttag gaaaaaatga taaggaagtt
      121 cttactgtga agaattttaa aacatttatc acaagcttta tcaatacaag attaggcttt
      181 gtgctaacgc ttctcttctg cttttggata aaaaccctat gggcttacca tgctgacttt
      241 tcactagatt tgggaaatgc ctatcaggtc tttctaacaa ttattaaccc aatccctcta
      301 gctttgttac tattgggatt taccctttat atcaagaata ctagggcctt ttatatcagc
      361 tcttggatcg tctatattat ccttaacctc ttgttaatat caaattctat ttattaccga
      421 gagttttcag atttcattac ggttagtgct atgctagcca gtagtaaggt ttctgctggt
      481 ttaggagact ctgctttaaa ccttttgcgc atttgggata ttgtttacgt ccttgatttc
      541 atcattctga ttagtttatc agtaactaag accatcaaaa aagacccgcg tccttttaac
      601 aagcgggctt cctttgctgt tacagcactg tcttgcttgc tcttatctgt taatctgttt
      661 cttgcagaga ttgaccgccc ggagcttctg actagaggat tttcaaatac ctatatcgtt
      721 agagcgcttg gattgcctgc ttttaccatt tacagcggaa accagaccta tcaagcacaa
      781 aaagagcgta acggagcaac cgctgaagaa ttagtcgatg ttaagcaata tgtcaagaac
      841 cactacgccg cacctgatcc tcaatatttt ggaatcggta agggaaaaaa tgtcattgtg
      901 atccacttgg aaagcttcca acaatttctt attgattaca agctcaagga tgacgacaag
      961 gactatgagg tcacaccttt tattaattcc ctctaccact ccaatgccac actagccttc
     1021 tctaactttt tccatcaggt caaggctgga aaaacgtctg atgcagagac catgatggaa
     1081 aattcattat ttggcttaaa cagtggttct tttatggtaa attatggcgg cgaaaacaca
     1141 caattcgcca caccatcaat cctagcacaa aatggcggct atactagtgc cgtctttcat
     1201 gggaatgtag gaaccttctg gaatcgcaat aatgcttata agcaatgggg ctatcattac
     1261 ttttttgatt caagctattt ttcaaaacag actgataaaa actctttcca gtatggccta
     1321 aatgacaaat acatgtttag agattctatc aagtaccttg aacagcttca acaacccttc
     1381 tacactaagt ttattaccgt cagcaaccac tacccttaca ccagccttag aggcgaaagc
     1441 agtgaagagg gctttccact agccaaaacc gatgatgaaa ccatcaatgg ttactttgct
     1501 acagctaact atctggattc agccttgaaa tcattttttg attatctcaa ggcgacagga
     1561 ctttatgaca attctatctt tgttctatat ggtgaccact atggtatttc taattccaga
     1621 aatgtcagct tggcagaatt actaggtaaa gaccctgaaa cttggtccga atatgacaat
     1681 gcaatgctcc agcgtgtacc atatatgatc catattccag gctataccaa tggcgggatc
     1741 aaagaaacct ttggcggaga aattgattcc ttaccaacct tactgcatat cttgggcatt
     1801 gataccagca agatggttca actaggacag gatctcttgt cgccacaaaa tagtcaaatg
     1861 gtagcacaaa gaacctctgg aacttatatc acgccagact acactagcta tagcggtcgc
     1921 ctttacaaca ctcaaacagg cttggaaatt acaaaccctg atgagatgac aatggctaag
     1981 gtcaaagaaa tacgagcagc cgttgctcag cagctagcag ctagtgacgc tatccaaaca
     2041 ggagacctac tacgctttga taccgataat ggtctgaaac ctgttgaccc aacaaccttc
     2101 atttatacca agcagctaaa acaactcaaa gagatatcag agaaattagg atcacattca
     2161 accagcattt atagtaaaaa tggcaacaaa tcaactcaaa agctctttaa agcaccttct
     2221 tatctggagt taaatcctaa agaagccgaa aaacctgaat ctacttcgtc ttctgaccct
     2281 aaagaagaat ccgttaagga acaaagtcag tagtggatgt ctaaagcaag cctcactagg
     2341 atcgctctcg tagaagacta aaagcaagct aaaagccttc attgagcgtt acaacttaat
     2401 gagggctttt tagttctgac acttttattg aggaatggcc tcaaagtatt ctggatctgg
     2461 tgtcggttca ggtgttggca caggatctag cttaggctca ggcttcggtt ctggtgttgg
     2521 cacaggatct ggcttaggtt cgggtgtcgg tgctgggcta ttttcttgcg tcacaatata
     2581 acccacataa cagtaatcat caaccttttc ttctggagtg taagtaaagc ttaccccctt
     2641 aaccgtagtc ttagtgacga tatcattgag atgacgtacc acatcaactg cactaacagc
     2701 tgttgtcgca ccaccagcta ccaacaaggc aatcaacaca tagctaccgc ttttcctatt
     2761 tttgtaaata agatagcctg aaacacttag taagcctagc cctactgcca aaccaaccag
     2821 accatctgct gcaccacccg ttttaggcaa gaccttagcg ttagccttag gggtagacat
     2881 cattcctttt ggagatgctg tcactccaca gcttttgtcg taaacaagaa cgtaatgcaa
     2941 tttatcttgg ataggtactt catttggagt gcctttttga atgcctgctt tttgttcatt
     3001 tgtcagatta gaataggctg tataggtcaa atctaccgtt accgtatcag cattagtgtt
     3061 ggcattgaca ttagctgcta gcaaagatag acctaacatc gttgtagctc ccatgtattg
     3121 aaacgcttta gaaaaacgtg gcattataac tattctcctt aatgttttgt agaataaaac
     3181 caataactaa aaaggcatct cctatcatat caatcttatg attattatag gtaaatgtga
     3241 tttttgtaag cactatctaa aaatttcaaa tacactcata tcaatagata ttgaccaaat
     3301 ctcagcagct ttaagcatat cataacaata aatcacctta ttgacacaaa tagaaaggac
     3361 acatttatac ttatcatttt cattctatta tattaaacca tatcttgtgt taaaatacaa
     3421 tgaaattatg acattatggc tcctaaataa gttgttttgc attttattat tttggtgatg
     3481 gatttgatta aaactagaaa tcatatatct ccttatatga tcatcacttg atggactgct
     3541 caactgtctg atacaagatt aagccctttc ttcttagtta acagctacca aagaaaggta
     3601 aattggctcc tttatactaa attagagata gctaaaaaca tctcaaatac tcttgacaaa
     3661 acgtcatgac tgtcttatct agctagatta gctaacataa ggcattaaaa atagacttag
     3721 aaggtttcta agtctacagt cgatctctat tatttgccaa gctttgcctt agcagcatca
     3781 gcaagggctg taaaagctgc tgcatcattc accgctaaat cagcaagcat tttacggtta
     3841 acttcgattt cagcaagctt taggccatgc atcaattgtg aatatgacaa gccattcata
     3901 cgagcagctg cattgatacg tgtgatccat agcttacgga agtcacgttt tttctgacga
     3961 cggtcacgat aagcatagta ataagaattc atgacctgct cttttgcagt acggaacaag
     4021 atatgttttg ctccataata acctttagct aatttcaaaa tacgtttacg acgtttgcgt
     4081 gatacaacgc cacctttaac acgtgccatt aatattctcc ttcaaataac tcttataatt
     4141 ctagtaaata cctgttacaa cccttaatct taaaggccag taaccattgc tttaatacgc
     4201 ttgaaatctc ctgcatgcac catacctgct ttacgaagat gacggcgttg ctttttagtc
     4261 tttccatgga aacggtgtga tgtaaaggca cggaagcgtt tcaaaccgcc tgaacctgta
     4321 cgtttaaaac gtttagctga tgcgcggtgt gttttttgtt ttggcatttt aatattctcc
     4381 tcttaacata tagtgtaata tgacaattac ttcttgtctg aaattggtgc aagctgcata
     4441 aacatttggc gaccatccat ttttgctctt tgctcaataa tagcaatatc ttgagttgcc
     4501 tcagcaaaat cagccagtac cttagcacca atctccttgt gagtaatcat acgtccttta
     4561 aaacggatag aaaccttaac cttatttccc ttttcaagga acttacgacc attacgaagc
     4621 tttgtttcaa agtcaccctt gtcgataact gggctaagac gtacttcctt tacagttaca
     4681 acgctttgct ttttgcgttg ctccttttgc tttttttgat actcaaattt gaactttcca
     4741 tagtccataa gcttggcaac aggaggaaca gcttgcggct ggattaaaac caaatctaca
     4801 tttgcagcat cagctaaaga ctgagcttca gataatggtt taatgcctaa ttgttcacct
     4861 tcaagaccaa cgagacgaac ttcgcgaaca cgaatctcat cattaatgaa tagatctttt
     4921 ttagctatga tcttcacctc tttatttttt tagagaaaaa cgaaagcgga cttaatgaac
     4981 caagcccgca cacataatat cccgtaggaa tttgacatgt agggccagac aacctaggtc
     5041 gcaaggcgag aagctctcac ttctgctttt ctcattattg acattctaac aaataaatca
     5101 tgccatgtca attatttttt ctgctttttc ctgaataaat tggacaacag ctgaaatcgt
     5161 gataccggta gtatcaaaga taatcgcgtc atctgccgcc tttagcggcg aaacttgacg
     5221 atgactgtcc ttataatcgc gtgccgcaat ctcagccttt aaggtgtcaa aatcagctgc
     5281 aatccctttt tcaatatttt cctgataacg acgctgcgct ctttcttcaa cagaagcaat
     5341 caaaaagatc ttcaactcgg catcaggcag cacaaccgtt ccgatatcac gaccgtccat
     5401 gataatagca ccagtcctag caattcgtcg ctgctgattc accagctcct ctctaatctc
     5461 tggcaaggcg gacacccaag aaacattatt ggtgacatca ttttgcctga tcgccattgt
     5521 cacatcttgg tctccaagaa aaaccagttg tgagccatca gctgcttttt taaaagaaat
     5581 tggacgcttt gccaattctt gcaggattag attgacatct tctttgtgat aaccattttt
     5641 taatgcgata taagtcgctg agcgatacat ggcaccagta tctaaatagg tgtagccaag
     5701 atttttggca ataatcttgg ctaccgtact tttcccactt gaggctggtc catcaatcgc
     5761 aattctaatt gctttcatct tttcctcttt aattatttga tattgacctc gtcacctgga
     5821 ttggcatacc agtagccttg ggtcatatga tctgggttta gggcctgtaa ttgctcaaca
     5881 gaaattccag cacgagctgc aatagatgtt gctccttctc ctgctaatac tgtaattgtc
     5941 tttcctgctg cctctgtaga aggtgctgtt tcagtcttag aaggacttgt tgtgtcacta
     6001 gctgctgagc tattagagct cgcttttggc tttgtttttg gttttgagct gaccttcttt
     6061 gttgtctttt tctgagttga tgccccgtaa aatcctgttg tctcattttg cttgttacta
     6121 ccgctgtttg acgtatagaa gaaaataaaa agtatggcaa caataatgac aaagaaaaca
     6181 cttaacaagg cagtcaacca aggtgtgcta atgagtgctc ctcttgattt tcttgttctt
     6241 gtcgccttat tgtcatcaac aattttttct tcccatggtt ctttagccat gattcttccc
     6301 ccttgttaat ttaacaaaat catattagaa taatacctat gaaagtatct atccttccag
     6361 aaaaatgcat tgcctgtggt ctttgccaga cctactctgc tctttttgac tatcatgatg
     6421 atggtatcgt caaattggct cagtctgatg agtcaagtca actcatagat cctaatgatc
     6481 atgatgccat cttagcagta aaatcctgcc ctactaaagc ccttaccctc gagtaagagg
     6541 ctttttttcg tattggtagg cttcaaaata atccagttta atgaagttat ctagtaatat
     6601 aacctctccc ttaaaataag gattaatcgc tagatcatct aaaaaatatt ttttaggcca
     6661 ttttctcatg taaaaaaggt agctcttatc accaacaaat agacaaaccg ttgatttagt
     6721 aacctcaatt ttggtaattg aggcaatcat cagtctgtgc ggagcaaata gctttaaaga
     6781 tacgatcttc aagacaccat tattctcaat tacaaaataa cgatgcaggc caagtcccac
     6841 taatatagca aataaagcaa acaagacaaa aacacgactc ggtatttctg ttctttcata
     6901 caataaggac aggccaataa aaataggcgc aacagcaatt gaccaataaa taatagacca
     6961 agacagctct ggctgccaat gataccttac tttaccgaat aatttaatca tgcttttcca
     7021 tcacctccaa tccgttctga gcattttggg tgatgttaag ccttttggac aatgccaaga
     7081 atcacatcaa ctgccttttc catcgtttgc agactcacaa attcaaacct gccatgcata
     7141 ttttcaccac ctgcaaaaat atttggcgtt ggaatcccca taaaggaaat ctttgagcca
     7201 tcagtaccac cacgaatcgg ctcgataact ggcttaatag ctaggtcctc cataacagcc
     7261 ttagctagat tcacaggtgt catgtccttt tcaatcacct ttttcatgtt atagtactga
     7321 tccgtcactg ttacaaatac acgctctgct ccaagctgac tattcatctc ctcagctagc
     7381 tgtgttacaa aggcctttct agcttcaaag gagctatcct caaaatcacg aataatataa
     7441 gaggcctgtg cttcttctac agtaccagac atgctgtgta ggtggtaaaa gccttgatag
     7501 ccgtccgttt tttcaggacg atcgtcaact ggtaattgac tatggaaatc cattgctagc
     7561 tgcagggcat taatcatctg atttttagct gtaccagggt gaacattgcg acctaacacc
     7621 ttgagctcta gggctgctgc gctaaaggtt tcatattgta gctcgccaag cggacctcca
     7681 tcaatagtat aggcaaagtc aacatcaaaa gcattaacat caaacttatc tgcaccaaca
     7741 ccaatttctt catcaggtcc aaaggcaacc ttaatgtcgc aatgctcaat ctgagggttg
     7801 gcaacaagaa actcaatagc cgtcatgatt tctgcaattc cagatttatc gtcagctcct
     7861 aaaagggttg tgccatcagt tgtaatcagg gtctgtccca aatattggtt gagatttgga
     7921 aaatcctctg ggcataaaga atagcctgac tgaccaagct taatctcccc accctggtag
     7981 ctctcaataa tctgaggggc tactccttct gcattaaaat cagcagtatc catatgcgca
     8041 ataaaaccaa ttttccgagt caatttgctg ctgttagctg gtaagcttcc aatgaggtag
     8101 ccattagctg gattgtaatg aatgtcctgt aggccaatag cttccatctc tggctttagc
     8161 actgttagag caaagtcagc ttgactcttg gtgcttggag ttgtagtgct tgctggattg
     8221 ctccttgtgt tgatttttac atagttcaga aatcgttcta ataaagtttc gtatgtcata
     8281 gatcacctcg ataagttttc gttactatta tagcataaaa ggacctaaaa tacttgccta
     8341 agctcagttt tttacagtgc tttatctgtt ctgttacagt tgcgttctca taaaaagaca
     8401 gctgccaaga aagctcttga cagccttgat tattcatcag cccatgcctt aatcctcata
     8461 accatttggg tgcttgcttt gccatctcca agtatctgta cacatccttt ctaagccgta
     8521 ctctgcagtc cagttaagct cttttttagc cttgctagca tcagcatagc aggctgcgat
     8581 gtctccttga cgccttggta atatcttgta aggaatagac ctgccaacca cctgagaaaa
     8641 ggcttcgata atatctagca cagaatagcc tgtacctgtt cctaaattat aaatagatag
     8701 gcttggctct tcagcaaact ttgcaagcgc agcgacgtgt cctttagcca gatcaacaac
     8761 atggatataa tctctaacgc cagtgccgtc cttggtctca taatcatcac caaaaacgcc
     8821 aacacaatcc agcttaccaa cagctacctg agaaacataa ggtaataggt tgttaggtat
     8881 gcccttagga tcctctccta aatcaccaga ctcatgagct ccgataggat taaaatacct
     8941 taacaataca atatgccact cattatctga tgcatagagg tccttgaaaa tctcctctag
     9001 catcagcttt gtcctaccgt aaggattggt cactgatagt ggaaaggttt ctaaaatagg
     9061 aacggtatgc ggatctccat aaaccgttgc tgaggagcta aaaatgatct ttttacaatt
     9121 aaaggctgtc attaccttta gtagggtcaa tgtgccagag atattattgt cgtagtaatc
     9181 aagtggaatc ctgcttgact ctccaacagc ttttagccct gcaaagtgaa tgacactcac
     9241 aataggatgc ttactgaaaa tatctgttag cagctgttga tcgcgaatat ctccctgata
     9301 aaaggtcact tctcttccag ctatcgaggc aacagcagct aggcttttag gatttgaatt
     9361 gcacaaatta tcaaccacaa caacgtcata gccagcagct agcagttcaa cacaggtgtg
     9421 tgacccgata tagcctgcac caccagtaac taaaatactt cctaacattg attatatacc
     9481 tgactttcta ataattacta atattataac tgattactcc caaaaagtat atctatcatt
     9541 tcattttaaa gaaatcagga taggcattaa tgtagccctt gccttcaata agatcatatt
     9601 ctaacagctt taagtcagag gccacctgct tttgagcagc agttagctgg ctgtcatcgc
     9661 tatttctggt atccaagaca tctgtcaaaa gagcgtagta aggagacacc ttggaatccg
     9721 tatgctctag caataaagag gtaaaatcac tggaattaac acgaggtcta gccaatttgt
     9781 tggtctgatg attgctccag atgaaataat ctgttaaata tttgacctcc tcatcattct
     9841 taaagacctg atctggataa aagccaggta aatgatcacc ataaaacaca actgtaatag
     9901 gcttgtcaac cttttccagt gctgataaaa aggcctttgt tgacttgtcg gtaatgctta
     9961 ataaattcac ataactttgc aggctatccg tctcagactg gtccagtcct gctaggctaa
    10021 catcaacatc tcttagctct gtgtaccaag ggccatgatt ttgcatggta atcactgaaa
    10081 agaattgact tcttttgggg ttaagctggt ctaaaatatt gtcataggtt gactcatcac
    10141 tatagcttga gctcattcgt atcaagtgct ttggcttgtc agctgaatcc tctgtggcaa
    10201 tgaaggtatc aaatcccaat ttgttgtaaa cgatttttcg agagtaattg ttggcgctcg
    10261 caaggtgcaa aacaatccta tccttaggcg aaaaggcatt actaatggca ggcgaaaact
    10321 tcaacttagg aaagacatca gaatacaaaa tcgaaactgt tggattgagg ttatattttg
    10381 gtaggccaaa taggctttga aactccatat tagctgtacc gccgccatag ccatcagagg
    10441 tcattaggcc actcgttgtg gtttccatga tatgatggat ctctgcaata ggatccttgg
    10501 ccaattgaac cccagaaatc ctagctgggt cagcaaagct ctcactcagt atataaatca
    10561 ctgtttgatc agaaatacgc tgatgccttt gcttattgat atcagcagct ctagcttgat
    10621 atttctgata aatcttttgc atagcgctct tgctatagcc tgaaggctga ttaatggtgc
    10681 tggtggtaac ctgcttgaac caaacaaagc tcaaggattg aaaccttgca ttggttgtaa
    10741 gaccatacca gtcaatatca aagacattgt agactgatga cagaactgga ataccttttt
    10801 tgatttcacc atctttattt tggctaaata caaaaaggat agaggcaaat accaaaagga
    10861 tagagcctat tgacatcagt ctaagataaa gcgctgatag gatcttttct ctaaagtatc
    10921 ttttatacaa aacatagatc agcagacccg acaagactag tatcaaaata atactaatga
    10981 tttgagtcag actaatgtaa ttcaagaaaa acttaatctc tttgatccat ttcaaatctg
    11041 aaaacaataa aggctcactt cgctgcttgt atttttcaat attaacaata ctgattaaag
    11101 ctccgatcac cgtattgaca aataaagcaa tgatatagtt gttaatgagc aaaaacacca
    11161 gcacaaaaaa gagggtcaag acaagcacct gaaacagggt tgcacctgga ataatcactg
    11221 ccccatgaaa atcaccatat gctgtgatcc cagcctgaat aaagtaatta aagatgatcc
    11281 ctaaaaataa gctggtcact agagctaatc taagacccca tcgcttgctc aaaacctcga
    11341 taaaggctgt gacgatgagg taataaacca caaacgtcag catataagag caaaagctat
    11401 acttaaagag attcaggcta acaaggtttg actgactatc taaaggccaa taatcatttt
    11461 gcttaatcac agtcttaaat aaagagctgt tcagcgttaa gactgaaaaa gcctgactaa
    11521 gtaaaatgac ttggattcct ctgtttgatt ggtagtcctt cttaaacagg tattttttta
    11581 agagaacccc taaaataagc aggctgacta aagctgccag actgagtagc atttcctgaa
    11641 tcgtacgatt actgatggta aacctgctgt tgtttttatt gatggctaag gtgatatagc
    11701 tattagcaac agcatagtag ctactgacag ctacagaaac aataagcagc tttgaggaag
    11761 catgcttgat cagcaaacat gccattccag ctattaacac taagacaagc cacgaaccat
    11821 aagctccctt atttaacgtg tttttgctta ccgcaaaaat agataaataa agagatgaaa
    11881 ggctaaacaa tatcatatca agcatttcta gatcaactaa ctggcgagct tttgaaatta
    11941 tcttcgttat tataatggtc acaccctttc ctaactgcta aaagctagac attactctct
    12001 gactcagaag cgattacctc tgttactaat tgacgaacag tgacctccca ggtaaagcct
    12061 gaaagcacct gctgatgaat ggcttcttgc aggtcacacc gtttttcttt gtgctcaatc
    12121 aaatgatcca actgcctttt aatatcagag actgtatcat caatgatgat tccctgtgac
    12181 gggctcgtta tcacttcctt gacaccacct ctatctgttg ctaatacagc acatttcaac
    12241 atacctgcct ctaatacagc tgtcggaagc ccttcagcat agatggacgg attaacaaaa
    12301 atatcagatt gagacagcaa agacatggtc tcagcaaaat tcagcttgcc tgtaaagatg
    12361 atggactgat cctctttata gctatctctt agtgaagcaa gcaagggacc atctccagca
    12421 accaccaaga cagccctgtc cttatatgtc agctgctcaa aagcctccag cagcaaaaga
    12481 atcccctttt ccttgatcac tcgacctgca aaggtaataa tgaccttatc ctgcaaagct
    12541 ggtaaataag cctttgactt aaagacctca taaagatcag aatcaactga attgtagatg
    12601 acgcctttgg cttttattcc aaaggtcttg agccatgcca tactgcgctt agacaccgca
    12661 taaaagtcgg gctgataggc tttgacaaaa aaggtaatta catgctcata gactttagca
    12721 aacaagtcta gtagctggtg acctttaaca ttttcgccca cctgaacata gccaccacca
    12781 tgctcgatca caatactagg gatggctttt cttttggcta gcttcaagcc catgaggctt
    12841 gtcaaataaa atcgtgtatt gcagatcaca aagtcaatac gttcttccat cagctccgcc
    12901 agcatgctat gatacagatc attcttatct aaaatcggat agcgctgctt aaatagctgc
    12961 tttgaaggaa atcggtaata agtaatggct tgatctcttt caatagggct cagctggtgg
    13021 ctgttgctgg ttacaatgat gatacggtag cctaggctca ctaattgttg cgctattttt
    13081 tctgtatacc gctctactcc tcctagatga gggcttgtaa agccgctaaa aatggctatt
    13141 gttttcaaag cttttccctt cttatgtata atattgcagc attgttcgag taatcatacc
    13201 taggatcaat agcaacgagc caataagaac ctgtttatta cttaataggc cttgggcctt
    13261 ttcaaggtat ttgttattag aggccagcaa gaccaacact aaagggatca cacccaaaaa
    13321 gtacctatct tgaaccccta gcacattaag gtctccaact ggcgtaaagg tcaaataaag
    13381 gctaaaggta ataccgccta ttattcctaa agacatcaat cccataccaa agcgagataa
    13441 ggtcggcagc tgaagcttgt tggcattagt gatgacaaca gcaaaataat aaaccatact
    13501 aattggcatg agctctacca taccgtatga taaagggcca aacatgtaaa tccctgaagg
    13561 attaaggata tgagccaacg tgtgtcttag cagcataaag ccatatacta tagggttcct
    13621 taacacagtc agtagctgct ctttagcatt gaccttctgg agaaagtcag ccatatccac
    13681 ctgaggtgac ttgatttgac catatacctt taaccaaaaa acagtcacaa ccagcaccgt
    13741 cagaattgac aacagcttta gcagaaacgt gcgagaggct tttgctccaa attgacgtga
    13801 agggataaaa agcagcaaca aaatcaataa aatataaggc agcttagtaa aggtaatgat
    13861 tgagcacagc agggtatacc aaaagagctt ggataaggga atcttttcag ttgtagccat
    13921 ctgaacaaat aaagaaatcg tcagaataat caatccaata gagacacaat cctgattata
    13981 agaaccagca agatagatat tcatcggaag gagacttcct acagcaagca gctgcttgcc
    14041 tgctgtcagc aatcgtaagg caacaaaaac caagatggca taggcaagaa cattacaaag
    14101 cctacctaaa aggtaagata agcccatggt caagcctaag ctccttccaa taaataagcc
    14161 tattacctgt ggtatgtagg caaagttata atagccattt gttgagcgaa tttccttaaa
    14221 tgaaatagcc tcatctgtat ggtctctgct ccacagctga aagcgtaagg gcttgccatt
    14281 gttgtggtcc ataagattaa tgtcatcagt caccagcagc tttgagtcat cattggttaa
    14341 attaagattt ccctcagata agtataaggc tcttgcaaag tgaaccctct catcaggaat
    14401 atcattgatc ggtgagatga aggcagagac agaacccata accacaataa taagcactgt
    14461 cgcatattcc atatttgaag gtaaaaagat aatcaaaagc gcagcaattg caactaatat
    14521 tgctaaaaat ttaatgggta aatccgttga ttgcgtatat aaaagcagca acacaagaaa
    14581 ggcaccaagt aaaacaagca aagccttact cgccttttgc aatttgtcaa ataaggtatc
    14641 taacatatcc tatttccttt tttccataat gtacaagcca tatgacaata gcagccaaat
    14701 catcattgaa attataaaac cataggtaac tccaatcacc ccaaagcttc tagccaaaga
    14761 accagtgatg gctagtgagg agataaagga tacaacataa ggtatcacaa gcaagtgctg
    14821 ctttctgata atggtaatca aattatcaat ataagtggca aaggtgctga taatccctcc
    14881 aaaaataaga agcataaaat caagctggta atgccttaaa tcaataccat aaacaagcga
    14941 tagcaccggc agccccacaa aatagctagc aagcaagata gctaggcttg ctaatagcag
    15001 cactagactg agacgacgct ctaattgtgc aaagctcttc ttgtcctctt ttgaatggta
    15061 aatggccagc tgagtgatca taggccttaa aaacaagaaa atcaggttaa tcataaaaat
    15121 aggcataaac aaaatattaa attctgtttg aacaccggct gggatcagct gctttgagta
    15181 aagctgctcc aaaacaaact tgggctggtt gtagatataa atgagtaaaa aaccatttaa
    15241 aaagagggga aagctctcct tcaatagccc taagatgctt tgagcatcaa tacgacgctc
    15301 aaggctcgta aaggaaactg aaggggttat gtcaaatagc acaatacaag ccactgaaat
    15361 aagacatatc acgatcaaag acaggactag ctgcttggtc agaaccagac agagcgtaaa
    15421 gccaagaatc accagcatat ttcgataaaa caaggatttg ccggcaatat ctaagcgctc
    15481 tctttgttga aacattcctt gaaacacatc agaaatggca tctgtgcaac gatacaagca
    15541 aatcaaccaa atcactagcc ccttaaaccc actatagctc cccaaataaa tatagagcac
    15601 tgaaatggct atcatcaaga aacaggtgac tagtcttgta taaaaatagt ctttgaagcg
    15661 gtacttgtgt aatatatccg ttgattggaa atttctaatc tgaaataagc caatagtaat
    15721 cagctgattt ccaatagcat aggcaaagct aaaggtatct gaagctgatt tagataagac
    15781 ccgagacaca atcatcagta aaatcactga tattagtgct gtcgagctgg ttcccaacac
    15841 attccaaata aaaatcgact gatccgattg aatcctactg ctggttttca tcttcttcct
    15901 gcttttcctt ctcattaagg gctaaatact gaatcatttt tttaagctta atctctgtcc
    15961 gagacaattt ttgagtgata aaaaattggt tgatgatgag taaaaaaatg attgatagaa
    16021 aaacaaaatt tgccggcgat tcaaagccta gcagccttga aaaataaacc gcagcatttg
    16081 gaaacagtga cagcaaaagc actattaaag agaaaaagag ccaaaaaaag ctatcttcaa
    16141 ttaaaatttt ggatctgcga atgctatcta gtataaacat ggctgtcaat aatgcaacaa
    16201 tgatcaaaat cagctgtaac ccaataaaca tcctcttacc tctttctaaa gttttgaatt
    16261 aaaataatcg aaataaacat gtgaaccatg tatttaatag atctagaaag agtgaggtag
    16321 ctttgaccag ccagcctatc attcatttgc acctgaacct cactcaccct atagccttgt
    16381 cgaataagat aagagatcgt atcaggctct ggagtatagt taatattagt tgcaaaaatc
    16441 ctgatcagct cctgattaaa cattctcata ccagaggtcg gatcggtaat acgctttcct
    16501 gtggttagct tgataaaaaa gctaataagg ctattgccta tcattctcaa ggatctattc
    16561 ttttcagcac tgacaaacct tgatccaatg acacaatcag caccagcatt aattgaatcg
    16621 ctcaaagcct caatatactc tggcaagtgt tgaccatctg catcgaactg gagtgcttta
    16681 gcatatccct ttttaaaggc atatttaaag cccgtctgaa tagcaccaga taagccaaga
    16741 ttttccggca aatcaatgat attgtaatgg ttatgatgac agatctctga tgtccgatcc
    16801 gaagagccat cattgataat cacataatca tattgaggaa aatgtctttt gatattttcc
    16861 actacttttt caatcgactc ctcttcgtta tatgctggaa tcattaccaa taagtctttt
    16921 ttcatatcgt caaatattct ctctattcat tcgtctaaac gcgtcttttt agcaatcgct
    16981 ttatgatata acggatagcc ttagctggcc caatcacaat atattttaag gctcctttta
    17041 tacctcccat atagtcaaaa tcgacatagg tatgtggcac actgccttca cgcaggttta
    17101 agagcttatt atcaataaat ggtgtcaata gcttttcatt tcttgaaatt ctaaaatcat
    17161 agtgtctgtc ccaagcaata taaattaaga gacgttcaat ggcatgcagg atcgaatttt
    17221 gagacagagg ctctgctgga atatcagcct cacttaggtc taagtcaaac aagggcttta
    17281 aggcatcgta tttaaaccaa acaaaggtgc catagctcat gacaaaggta tccatcgtct
    17341 gaaaatcaat gcgttttgta agccccattg cctgccaaag ctgattcatt tcaggggcaa
    17401 taaggtgctc attccaagcg tcaacaattt tattaaaacg gaaaaaactt ggaatatctg
    17461 ctatcacaat accgatagca tcagcagcca gtgctgttag gatttgatcc gccggcttca
    17521 ccatcatatc aatcaattca gtgcgccagg attggcccgc ccaaaaatct gcttcctttg
    17581 attttttggt atgaaaatgc ccaatataat catattgaga caatcgttcc tttaaggtca
    17641 gcattggcaa gacatctcga ccgatatttc ctgtcaccaa tatgtcagca cttgccccgc
    17701 tttctcgtag aatttcttta atctcagcct ttttagcctt gctatcggtc gttatgagca
    17761 agtcataatc aaaatgaaaa tgactaaatg cttctaaaaa ctctgacaat aaatcaacat
    17821 aaaaaacatg aagatgaaca gcaattttct tgctttgatc aatgcttatc ggctgctctg
    17881 gcaggtattt atgtgccaga agatacttag catctggtgg atggacctgc gacatatgat
    17941 ccacaatcaa gctggcaggg tatgtcgttt tttggtcaat aaaatccaaa aggtaaggag
    18001 caatgtgctg gttagcgtca atagccttaa ccttgataaa gggcacatgg tgctttaaga
    18061 tggctgtcgg attgtaataa gagaaatccg catgcagcat agaggacgag tcctccttgg
    18121 tcgtatcaaa taccgtcttg tatcgaaagc cagcctccac aaagacagtg gttattctgg
    18181 tttcataatt gtggatcaca tcttgaacgt ctgttagctc aacgatattt tcccaaaact
    18241 gcctaaattc cttactatga acgagggatt ttttgaagct gataaaatag ctctgaatat
    18301 gctctttaaa ggccttggtc gctcgattgt tggtcatgcc ccagaaatca actgcttcat
    18361 ctgcttcata tttgagataa taaggcttca tatcccaaag cggaccaaag caggtatcgt
    18421 tcataatcgt gattgagtca aagtcaacaa ggtgctcaca gcctaaggcc ttcataccat
    18481 catgccaagc tgcaaaatca tagcctttat tgtgtcgttg aataaactga tccatcaaat
    18541 gccgctgttc aagctgctca aggtcctctt gatggatatc actatttgaa ataaagacaa
    18601 tctttgaaaa caaggctctc atctgttcga gctggtaata aacatgatcg cttaccttat
    18661 gatatttatt gaaatgcaca tacaataata gacgcttcat tttttcctcc taaaaagctc
    18721 aagcagcttt gataggtacc tccaacgacg tgaggtaacc acacaattgt attgatgggt
    18781 tagcgcttca acctcttgcc tttgatgatc aagctgctgc tgtagctgat ctatcttctc
    18841 tgcctgtaga gcctcctgat ctgcaagcgt ctgtcgtaat tgatgaatgg tatgacttaa
    18901 ttgatgaatc cgaatttcat ttttagcgtc ctgctttagt aatgcttttg caatagcttc
    18961 catattggct gtagggtatt tagacaaata ggacagctgg gtctccaaca agccttgaat
    19021 acggcccagc attttttcct ctgctgccgg ccttgaatct gaattatccg tcattcgata
    19081 aacagtggtc gaatccttca aataggctag agaggttgac tgaaacagct ctaattgtat
    19141 gtcaaaagtg tcgtctgacg tctccaaatc aatgcgttga ttaactgccc tcatcagatc
    19201 agcctccacc agccaggttg atgacatggt cattcctttt aaagcaagca ttttctcgta
    19261 ggtgtctgtt aagggagtaa agccactttc aaaggcattg ctctgaataa gcttgccgtc
    19321 agtatctaca aaatcaaagt cagtattaga ccattttgaa tctggtgagc tatccagcaa
    19381 atcaacctgc ttttgtagct tgagagtatc agtccaatag tcatcaccat cacatctggc
    19441 aatatactgt ccctttgcct ccaaacaagc cttgacccag gttcttgcaa tcccaagatt
    19501 tacctcatta acgatgagtc gtatacgatc tggaaagctg gcttgatagt ccatgaggat
    19561 ctgtctggaa tagtctgttg aagcgtcgtc aatgacaata atttcaacat caaagctggt
    19621 ctgttgggct aaaaagctgt ctaaggcctc tgaaatccaa ggccccttat tataattggt
    19681 gcaaataata gaaacttttt tcataggatg ctttctaatg acaattattg attaatgagc
    19741 cagctaccat ttctttgata taagccactg gcagagtcca aagcagacag gtcatctgga
    19801 gcaatatcgt ttcgttgaag cacgactaat ggggaatgat tagctgttaa aaagagcagc
    19861 atttgcccgt tttgatcgcg aacagtcacc tcaagcttta atttgatatc atttaggtgt
    19921 gagagctgac actggtagga tatgttctta tgaccaggac cacttgtcgg ttgatcctgt
    19981 gaattgtcat tatataccca aatattgcgg tcaatatcag tcaacgaaaa ggcaacatag
    20041 gtaggctcgt cctttaagac atgataggaa atctcaaagg aaatgggctc atctggacta
    20101 aggcttggct tagaggtcaa cctcacctct aactggcttg ccaaatcaga cacaggctca
    20161 gcagcagctc cttgctcagc atttttcaat tcagtattat caacactgta ttggttagcg
    20221 acatcaaagg gttcgccgta agccttgaca aggccatttt cgatgaggac tgcgcgattg
    20281 cagtattttt tgacagcccc catatcatgg gtcactagta tagtagtctt gccgctctcc
    20341 ttgcgctcca tgaagtagtc attgcatttt cgttgaaagg cctcatcacc aacagctaac
    20401 acctcatcaa gaatcagcac atctccctgt gccttgatag cgacagaaaa agcaagacga
    20461 acctgcatgc ctgaggaata attttttaat ttttgattca tgaaatcatg cagctcagca
    20521 aagtcaacga tatcatcata catatcatca acctcttctg tggtaaagcc cagcattgcg
    20581 ccattcatgt agacattttc acgcccagtc aactcaggat taaagccaac accaagctcg
    20641 atgaaggaca ccattttccc ctcaactgtg acctgtcctt tttctggaac ataaatttga
    20701 gaaataattt ttaataaggt tgattttcca gagccatttc gtccaacgat gccaaaaaaa
    20761 tcccccttat acacgtcaaa gctaatatcc cttagcacat gctgctcggt atagccctta
    20821 atgcctttaa aacggttaac aagagcagta cgaaagctct tggttgcctc tgttggcagc
    20881 ttaaaggact tactgacatg atcaactgtt actgcaattt ctttattagc cattagataa
    20941 tctccgcaaa cttcttagca tttttattaa acactgctac cccaagtgct aataggacaa
    21001 atggaatgag gtaaggaatg atgatatagc accaatttgt cgacatttgc caaatggtca
    21061 cattagctct gtcaatcagc agataccgca aatcttgaat aatctgtgct aaaggattaa
    21121 gcatcaaaat cttggcagca agagggtgtc ggtcaaacac aaaggtaatc gggtagatga
    21181 tgggagtcac atacatacct gcctgcaata gaacctccca aacctgagcc aaatcacgat
    21241 aataaacaaa gacggtagaa agcatcaagg ccacaccaac tgtaagaaca gccagctcaa
    21301 caaagagtgg taaggccaga taagcgtgag gagataaagt aactccattg atagctgcaa
    21361 aaaccaaaac cactaatagg ttgattgaaa agttaatcaa tgctcctaaa actgctgaaa
    21421 aaacgatagt atgctttgaa aaattcaatt ttctaagcag gtctcctcgc gatacaatag
    21481 agaccattcc catactggtt gcttctgaga aaaaggacca aatcacattg gcaagtaaaa
    21541 gagcaaccgg aaaatgagga acgtcaccac cagttcgcaa aaacctgata aacaccaaat
    21601 acatgatggt aaacatcatc aaaggcttta agatagacca caaataacca atagcactgc
    21661 cctgatacct tagtttaaag tctgttttaa caagctcttt caaaagaata cgattctttt
    21721 tactcaataa ttccattatt cttttctcct atagccaaat ttggtcatga tcaatgccat
    21781 aaaaacaagg gtatgaaagg cacgattttt ccgaaagcca tacgctttga aatcagacag
    21841 acgctgatag aaaggcctat ccaaaagccc tacgtaagcc tcaatcaatc ttctgtcagc
    21901 cggatttagc tgcaagtcta gcaattgcct tgcttgatgt tgactagaaa caataagcca
    21961 ccaatacttc tctatgagct tatggggctt acgccactgc ttcagtcgct tagaccaggt
    22021 tcttgcccct aaaacattag catcatgctg acgatagagc tctgttgcca catctagata
    22081 cacaagctct ccctgcgctg ctgcaatcaa ggctaaatac caatcatgca tcaccacatg
    22141 ctcacagctc acccactgct ctgccagcgc gtgattaatc atcatagtgc cgcctgtgac
    22201 tgtgttttca gtcaactcct ggactagctg agtattagca tgatgtgatt gtgtttggat
    22261 catactctca tgacgtactt ctaagtcttg attgaccacc tttaggtctg tgtagactag
    22321 taagggctcg cttatcttgt gcttttgcgc ttctgccaga gtaagctcta atttattgtc
    22381 taaccacaca tcgtcttggt cactgaaaaa ataaatatct gccttttcat atgttaaaag
    22441 ggtgtgaaag cttcgaatca caccgaggtt ttcctgcaca tcagcattaa tcaagcaaat
    22501 tctcggatcc tttttagcaa aagcctgaat gatggcaagc gttttatcag tagagccatc
    22561 atctctgact aataaggtcc aatcctgcac cgtctgcctt tgaatgcttt gtatttgctc
    22621 tgctaaaaac cgcgccccgt tgtaggtaga cattaaaata ttaatcttca tctaaaaata
    22681 aggcctcata ctctcctaca attttctccc aggtatattc tttggcaatg atttgcttag
    22741 ctctttctcc caaatcagca aacgattcct tttgatcaac cctgttaatc agtccagtaa
    22801 ggctgccctt ttcttttgtc caataaaggg ctgctgtttt agcaactgat tgattaaagg
    22861 tcactcccaa aaccaaatta agctgggtat gggctagggc ctccaaaaga cctggattgg
    22921 tacctccaac ctcatgccca tgaatataag caaaagcatg ctcacgaata taagctaaaa
    22981 gctgcttatc atactgtgtt ccaacaaatt ttacacgcgc gtccttatca cagccagttg
    23041 cactaaccag ccgctcaaaa taaggatttt tgtcatggtt gcaaataata accaaatccc
    23101 gctgagtaga tgatgccata aactctctaa tggctgtttc atagttgttt tcaggaacaa
    23161 agcgccccaa aatcaaatag tattggtttt ctgttatctc aaatgtttga aagtaagttc
    23221 tgactttttc atctgatgta gacaaacaag accgccctat ttctgtccca taggcaataa
    23281 aagtcgtttt tgcccaagga taagactttt tgatgtaggc ttcaatgcca atattatctg
    23341 agatgaccaa atcagcatgc tttgtcattt gcttttcggc gtatttcagg tattgctgaa
    23401 caggcttaga ccattttgaa cgcttccatt ccagcccatc aggattaatc aacaaacgcc
    23461 caccacgctg gtgaatctgc tttgcaaagg gggcaataaa gcctccaatg gtattgccta
    23521 gaacataaaa aataggcttt tgaatatgat acctatcaat ataagctaaa gcgtgactaa
    23581 tagccatcat atcataagca atcactctag ctggaccgag cttaggagga ttgatataaa
    23641 aacaatctgc tcccttgtac acaaaatgct ccttgtgctt gctatcgctc aagcaggcaa
    23701 tatgataggt aatgcttttg ttggtctgat tagtgactaa ttcttcaaca aaggtctcaa
    23761 aaccaccata ctttgctggt aaaccgcgac ttccgatgat gaaaacatcc tgcatagcac
    23821 actgccccat tctaaaatat aattagtagt attataccat ataaacaggt cttatgcgac
    23881 ataaaatcca tgaaaagaga gccaatctcc tagatcagct ctttagtgct atcgcttatt
    23941 cattgctgtt gcttgtaaaa agcctccagg gcttcttgcc aggtaggaat cacaaaacca
    24001 gttgccttag ccttatcaag attcatggtt gagttaaagg gtcttttggc tttagcagga
    24061 aaagccgatg aatccacagg cacaacctcg acagctgtct cttttaagat ttctctagca
    24121 aaatcatacc aagtggtgtc ttctttagca tcatttgaca aatgataata gccataaggc
    24181 ttgcgattgt ctgctagatg acacataaac tcagccaagg tcctcgtcca ggttggacgc
    24241 ccatgctgat cattgacgac tgtcaagcga gagtgggtct tagcaaggtt ttgcatggta
    24301 aacacaaaat tcttgccata atgaccaaac acccatgcgg tacgaataat gtaaaattgc
    24361 ttggtatatc gctcaacagc cagctcacct aagcgcttag cacgaccgta tgctgtttga
    24421 ggatcaggag tatctgtttc tagccattcc tgaccagctg gcttttgacc atcaaaaacg
    24481 taatccgttg aaatataaac caaggtcgcc ccgtagcgct cacaagcctt ggcaatatgc
    24541 tcagtaccag ctacattgat agcttcattc agtgcttttc cttcttcttc agcagcatca
    24601 actgctgtgt aggctgcaca gtgatacact aagctaggct tgacctgagc aaaaacctcc
    24661 tctactttag tcgcgttggt aatatccatt tcagcaacat caacagcaac ataatcgacg
    24721 cttcgttcgt ctaaaagata acgaagctct gttcctaatt gaccattact tcctgtaatt
    24781 aaaatcatct tttctccttt gtaaaggtct tatttctttg agctaatcac gcagctcact
    24841 cccatctaat cctaagagag gcttttttga tcagctgacc ctagcaagac ctttgttgtg
    24901 gtatcgtatc agccttgctt tttatctagc taccgaatac ctagggcaat tctcgcatag
    24961 cggctcatct tttcaacgct ccaaacaggg taccagacca actttacctc aaccttggtc
    25021 acctctggaa catctctcat cgcatcatga atatgatcag tcaacaaatc cgccaaagga
    25081 cagcccattg tggtcaaggt catgtcaatc tcggtatgac cattgtcatc aaaacgaatc
    25141 tcatagacca agcctagatt cacaatatca atacctagct ccggatcaat aaccgttccc
    25201 aaagcttcaa gaatccgatc cttgatagct gcaacctgct cttctgtgta ttttaatgtt
    25261 tcagtcatag ctattccttt cacttttttc gaagacctga tatgatgcca agtcaaaaac
    25321 cagcccaaag accagcgcat tcagcatacc tatgatgccc taagctgact aacattgata
    25381 gcctcttttt agtcaccctt acattaacac tagtctttag ctactggcta gcaaaggtaa
    25441 tctcataaac cagtaactag gcttggagtc gttgaccata ggccactcac cgtcaaggag
    25501 agataacgca tttcgggctc gtctcctatt tttagctcgc cgttaaaaag gtccaccgga
    25561 cctttttaat cctcaatgaa gtctctgagc tgcttgctgc ggcttgggtg gcggagctta
    25621 cgcaaagcct tagcctcaat ttgacgaatc cgttcacgag tgacattgaa gaccttccca
    25681 acgtcctcta atgtacgcat tttcccatca tcaagcccaa agcgcaggcg aagaacattt
    25741 tcctcacgat ctgtcagcgt atcaagcact tcgtctaatt gctcacgaag aaccacacga
    25801 gttgtgtaat caacaggatt ttcaatcact tcatcttcaa taaaatcacc taaatgactg
    25861 tcatcctctt caccgattgg tgtttcaaga gacactggct cctgagcgat tttcagaatt
    25921 tcacgcacct tatcaggggt catctccata cgctctgcga tctgctctgg agtaggatcc
    25981 tgccccaatt cttgaaggag gttgcgctgc tcacgcacta gtttattaat ggtttccacc
    26041 atatgcacag gaatccgaat ggtacgtgcc tgatctgcaa tagcacgagt aatggcctga
    26101 cgaatccacc aggtcgcata ggtcgaaaac ttgaagccct tagaataatc aaacttgtca
    26161 acagccttca ttaagcccat gttaccttct tgaatcaaat caagaaattg catgccacgc
    26221 cctacataac gctttgcaat cgacaccacc aaacgcagat tggcctcagc aagacgctgc
    26281 ttagcctcca tatcaccagc ggctactgca accgctaaaa ccttttcctc atcacttgtc
    26341 agcagcggca ccacaccgat ctccttgaga tacatgcgca caggatcgtt gaccttggct
    26401 gaattacttc cgataagctc ctcgtctgtc agctcctctg gcttaggctc ttcaacgacg
    26461 tatttagatg agggatttcc ttccttatct gtaatggaaa tgccaccatc tgtcaaacgc
    26521 tcaagcaaat catcaatttg gtcagcatct aaggtaaatg gaatcacgag tttttctgtg
    26581 acctcatcat cagtagctgt tccttccttt ttatgatgac gaataaactc cgcaatttga
    26641 acgttaaagg ttgtaatttc tttttctttt gccatatttt cctctattcc atttttcttt
    26701 tttcagcaat gaaacgctct aaagcctcta gagccatctg gtggtcaccc ttactgctag
    26761 attccctaat ctgctttcct tgcctatgca gctctctttg ctttagcaat gtcatttgcc
    26821 ttgataaaat atcctcaatc tcaccgctag ctatctcatc aggaagattt tcctctaaaa
    26881 cccggtaata ggcttggtta acctcttcag acagttgcga taggtcatag gaggtaatct
    26941 gccctgtggc ctttagctgc tcatacagcg tctgaagggc tggtgtatca aaataaaaat
    27001 ccggccgatg acgaaattca ttgagcaaat agtcgtgatg aagcaggcga tgcaggaggt
    27061 gactttctgt tttagccaag gctgtcatgc ttttgttaat cggtaaggtc accagagatg
    27121 cctttggttg actagcctgt ccttgttgta agctttgcct atcttgtagc cttaaagcat
    27181 ttaccgattg ctccacctga aaataatcaa aatccggcag caaatcagcc accttattaa
    27241 tatacgaatt ttgtgcggtg attgagggtg cttgagcaat aatctgtgat atatgctcca
    27301 cataagcaat ctgcgattgc aggttatcca tattttcagg cttcaggtga tcaatcaaaa
    27361 actcaacact gctaatgcgc gagtgctgga gcaattctgc tagagcctct ggtgaatgct
    27421 gctgaacaaa ttcatcggga tccattctat ttggtatttt cacgatctcc acttgaaaat
    27481 ctgccagcag ctcaagagac ttggcaatag cattttgccc ggcgtcgtca ccatcataag
    27541 tcaatacaac cttttgtgtc agctgcttga ggtgcctaac atgctctggc gtcaaggctg
    27601 tccccataga ggcaacagta ttaccatagc ctgcccggta ggctgcaata acgtccataa
    27661 agccttccat caaaaagacc tcatgagtct tagcgattat cggcttggcc ttatcaaggt
    27721 ggtaaagctc ataggacttg ttaaatagga ccgtagccct tgaattttta tacttggcct
    27781 gctgcttttc tatatcctct cttgcccaga tacgtcctga aaaagcaatc atattgccct
    27841 tatcatcaca taagggaaac atgattcgat gacgaaaggc atcataaata gcatttgatt
    27901 gttcagaaac atgaaacaag cctgaggctg ttaattgcgc ctcagtatac ttttttgaca
    27961 aggcttgata aaggtagtcc atctcgttag gcgccaagcc aatccgaaaa tactctatta
    28021 gctgatcatc aagccctctt tgataaagat actccttggc tctttggcca atctttgtcg
    28081 tcatcaaaac cgcatggtaa aacttagcag catcttcatg aagatcaatt aaagcctgat
    28141 gagggtgctg cttttgactc aaactagtct gacttggagc aacagtaact gccataccag
    28201 ccttatcagc cacaatctga acactttcta aaaaaggaac ctgccgatat tcctcaataa
    28261 acttaaaaac atcccccgac ttaccgcagc caaagcagtg aaagaactgt ctatcttcga
    28321 tgacattaaa agagggtgtt ttttctttat gaaagggaca caatccaagg tagtgccgac
    28381 cagcccgcga tagatggaca acttctccaa taacatcaac aatattgaca ttatgcttga
    28441 tctgagaaat catctctttg tcaatagcca aaccgtcacc tccccacaaa aagcccattg
    28501 taaatttaca tttcattata ccattgaaaa tgagctttgt aaattgtaaa agcacaatcc
    28561 ttcatcatct aaagcccgct acatcaagca ataagctatg ctaaagtatt gacgtctctt
    28621 atgatcacta gcttgactag cagtacagca ttaagtagct catcagtcct tgataagctc
    28681 ttctattagc ctttttgacc tatttgtgct atgataagat tatctgaaaa aaggggagtc
    28741 aatcatgctc aaagaattaa aagcattttt atttagaggg aatattatcg acctagcagt
    28801 tgcggtgatt gttgggagcg cctttagcgc tattgtcaca tcatttgtca acgacattat
    28861 cacaccgctg atcctaaacc cagccttgaa agctgcaaat gtggaaaaca ttgctcagct
    28921 cgcctggaat ggcatcaaat atggcagctt tctcagtgct attatcaact ttttaattgt
    28981 tggtaccagc cttttctttg tggttaaggt cgctcaaaaa gcaatgccta aaaagggaga
    29041 ggaagagccc gctaagccca aaacaccaac tcaggaagaa ttattacttg acatacgtga
    29101 tttgttagcc aaaaaataac tcaaagctct tacagcagct ggacctgtcc ggctgctttt
    29161 tgatatacaa gcacagagca cttagcgatc aaaagataat agaaccggct ctatttgctg
    29221 ttttagcata tcattgctat ttttatcagc agcaagctaa ggtaaaaaaa gacaaactag
    29281 tatcctcata ctggtttgcc ttcaaactaa ggcagcctac aaagggccgc cttttttatg
    29341 atgattagaa ttttttacgt ttgcgagctg cttctgattt gcgtttacgc tttacagaag
    29401 gtttttcgta gaattcacgc ttgcgtgatt cttgaagagt accagcttta gtaacagaac
    29461 gtttgaaacg acgaagagca tcatcaagcg attcattctt acgtactact gtttttgaca
    29521 tatgtttcac ctcctcaaga tattgtaaca ttttcacgtt ctagcttatc ttacatgatt
    29581 tttcggaaaa agtcaatgat cttttcttga ttttgaggtc attcttaaaa aaatacctta
    29641 aaatttgctg ctgcattagg catcacttgg caaggctatt ctactgcatt tcctgttaat
    29701 aatgctgctt cttgaataaa ggccttgtat ttgccatcct tgtttaattg cttgatcacc
    29761 ttattaatgg tttgccttag gtcatcactc ccctttggca tagctacagc cttagcatct
    29821 ccatcacttg cctgcaattt aaatggtgct aaagccaggt ctttatgttg agctaaaaag
    29881 cctgcagcta ctggtgcttc caaatcaaca gcctgcacct gcccagattt caactcatta
    29941 atagcctcac ccatcacagt tagagaaaca cagttggctt tattaagctg ctccttgact
    30001 aggccctcct cgatgctgcc tttttgaaca gccacctttt tgccaactaa gctatcctta
    30061 ttagcataat gcttggcatc tgacgctttc accaaaatag cattttcagt ttcatagtaa
    30121 gcctcagaaa aatcatacac tttggcacgc tctttggtgt aggacaaacc agaaatcgct
    30181 atatccacct taccagtttg cagactggat aagacattat caaaattcat agcagagagt
    30241 tcaagcttaa cccctagttc atcagcaatg gcctgtgcca gctcaatgtc tgctccgaca
    30301 atagtatcct tgccgtcaac caaggcctta aattcaaaag gagcatagtc agggctaaca
    30361 gcaaccacca gctttccctt ttcctggatc ctgtcttgaa ggctcgtctt gttagcttgg
    30421 ccacaagctg ccaaagcaaa aacagatacc atagcaagtg ctccaactaa taatcgcttc
    30481 atgttcatat tataattatt ccttttcttg ttgatgaatc ttattatatt gcattattat
    30541 tcaatggtca agtttttatt gaatattttt caagcactgc gatagtctgc ttaatcctgc
    30601 ctgtagaacc tgcggctgac agcaatagcc gattctcaca tgatttgctt gattaaagcg
    30661 atttcccgga acgaccaagg taccgtaatc ctccagcagc ctcaaagcaa aggcttccat
    30721 gtcctcatct atatctagcc taacaaaggc cgttgagacc tcattcggtc tatggtagga
    30781 ggccctggct tcacctgtta tccagtcctc taagatagca aggttagtcc tgataatggc
    30841 ttgattgcgc tgcaatagct tgtcagcatg cttcaaggct agcgaagcca ccatatcatc
    30901 aaaaacacct gcacagatca ttgtgtaatc tcgatataac ctaagctgat cacagatggt
    30961 ctcagaagcg gctacccagc caactcgaat gcccggaatc gaaaaggttt ttgacatgct
    31021 attaacagta atccccttat catacaaatc tgccaccgct aaaagatgat cagaggtaaa
    31081 ggaatgataa acctcatcac ttagcaggta aatatcatgc tctctagcaa tattgatgag
    31141 ctcctctaaa taaggcttgg tcatataggc acctgttggg ttgttggcat tgttgatcat
    31201 gatcattttt gtgttgggac gaatcatggc acctagctca ttaaggtctg gcagccaagc
    31261 ctgctcctct ctgatctgcc aataatcaac ctccactcca agagaagctg gaatatcata
    31321 tagctgctga tagctaggat agtgagcaat cacatgatca cctgcttcaa gcagtgcata
    31381 aataaccaaa aaattggcac ctgttgcccc attggtttgc aagatatttc tagctttctg
    31441 ctgctgataa agccctgcca ctgcctgctt aaagtcagga gagccttcta tccagccata
    31501 gtctaatggc ttttgatgca gctgctggta aaaggcttga ggctgctcct gtgttaagtc
    31561 aaagagctcc tcaagcgtta atgaagcaat agatgagcca gcaatatcgt atacagcacg
    31621 tttttcatgc tgatttagcc actcttctac accaaatacc ggtagtttca taagatcacc
    31681 ttatttcttg cgtaatattt attacaatat cgcataaaaa tacaattgtc aaatcaaaaa
    31741 ctatcctttt tttgataaga atcatgtcct atctaacagt tagtcctgat tggtctcgca
    31801 tgaaaggcta ctaaatagag caaaaatcac ataaaaagac tcccaaccca ccaatcagcg
    31861 ggattaggag cctgatagct cgtatcaatt cattgatttc agatcagagt gactatcatc
    31921 actctactat gagccaatga ctaggctagg cggacaactt ctagctgtga tccacccatt
    31981 aataccaagt atttttcgat ccttgcaatc ccgtaggatt ggctcagagc ctcggcatat
    32041 aggtccattt gctgctgata gcgctgcttc agctcagctg actgctgata gcgatctgtc
    32101 ttatagtcaa aaagaacaat acgatcctca aaaagcaggt agccatcaat aataccacgc
    32161 actacgtact gctcctgact taggctgtct tttttcagca tcgcaaaagg agcctcgcgg
    32221 tgtaggcgct ggtgatgctc ttgcaggagc tgccccaatt cagttgtcgc aaaaaaagag
    32281 gttacctttt caatgtcaag ccttgccttg acctctgcgt cagctgagac aagctgtaag
    32341 gtctgttcaa tatcaccagc agtaacctga tcagacattg gaatacgctg catgagctca
    32401 tgcaggcttg agccgacctg gctaggctca acagcctttt tcttagaaaa atcaggaagc
    32461 tcaaaggtct tgggcctatg ataaggctga tctatgatat caacaccatc agtatccatt
    32521 agaggctcat aaagggtttt aagctgactg ggggttctca ccgtcggcag ctcaatggcc
    32581 gcctgatagc ttgcattgag ctctgacacc ttatccagca tgtctaaggc acgcgcaatg
    32641 tcctctgttt gacggttatc cttgagatca tctgcttgca gcagccctga gggccttagc
    32701 tgaccaacag cttctggtgt taagtcactg tcatcaacaa atcgcacatc aataaacaag
    32761 tcctccttgc taaatgttgc tgctatcgct agtagccagt cttgaaagct cagcaatctt
    32821 tctcgactag ctaaggctaa gcgtccttcg gagctattgt cggctgtttt ttcctgtacc
    32881 ttttccttgc tagccttacc aatgaggtat accttttttt ctgctcgcgt catggccaca
    32941 tacaagagac gcatttgctc tgataaggtc gccaagcgta gctgctgctt attgagctgg
    33001 taaggaagag tttccatcgt aaccttgagc gacgccaatt tttcttctct tagaagctcc
    33061 tttacattgg cgacatattt gataccgatt ccctcatctc tatttagaat gattggcgcc
    33121 tgtaggtcag ccatcgcaaa gcgcttgtcg caattcaaaa tgaacacgta atgaaattca
    33181 agtccctttg atttatgaat tgtcatgagg ttaacagcat gcttaggcct ttcgacctca
    33241 acatctgcca aatcattttg cgtctccagc accttatcaa tcatgccaat aaagcgtgag
    33301 agtcccttgt agcctgattg ctcaaattgg tcagcccgta tagcaagggc gtaaaggttt
    33361 gcctgagcct gctctgcctt tggctggctt gctacaaagt caaagtaaaa gcgatcgtta
    33421 aaaatcttcc aaatcagctc ataaagcgaa tgaagctttg caaattgacg ccagtctctc
    33481 aaggtcccat caaaatcagc cagctttgtc atcagctcct gaccgatcag ctctgggtgc
    33541 tcgccttgtc ctctcaagct attgctaagc ttgtcataga aggcttgagg ctgcttttgt
    33601 gagctgcctt gcagtgagat tcttgccagc tgatcctcat caaaggaaaa cattggcgag
    33661 cgcattaagg ccactagggc ataatcattc aaaggattgt tgatgcttct tagcgtatcc
    33721 agcatgacca tcacctcaac tgatttgagg taattttctt ggccaccatc agcaacgaga
    33781 ggaatgccat actgattaaa gacctgaaaa atagtgtcat ttcgtgtgcg tgacgaaaca
    33841 agcagggtaa tatcttcaaa agcaaccttc tcctcgttat agagcctgat gatttcctta
    33901 gccactaaga tgacctcacc tgcggagata ccatcgttag ctaaggcttc ctcggtgcct
    33961 tcttgaactt gatcggtgtc atagagcagc aattgggctc gattgttagg atatggctgt
    34021 ctttgtccct cactgcctgc taccagctgg tgcttgtcat cataggtaat ctctcctaaa
    34081 gactcgtcca taaggcggct aaagacagcg ttggtgacat ttaggacctc tgactgactg
    34141 cggaaatttt cctttagtaa aatcagcttg ccatgctcgg gattgctttg ataatcctta
    34201 aacttttgat tgaagatttg aggatctgct tgcctaaagc gatagatgga ttgcttgata
    34261 tccccaacca taaaacgatt atggccatta gacagcagct ctaataggcg ctcctgcatg
    34321 tgattgttat cttggtattc atcaaccatg acctcatgat aatgaccttg gtaagcttgg
    34381 cgaatatctg gagcctgttg taaaatctca atggcaaaat gagctatatc tgaaaattca
    34441 aaggcatttt cttgcatttt tgcagccaaa taagcctctg aaaagctgat cacaaaggct
    34501 tgcagcacct ccaaaagtgg taagctctcc tgttgataag caaggatagt ctccaagtgc
    34561 ctaaatctta ccagctgctc ctgtagcgat ttgaaaatag ggtatttgtg accggctaca
    34621 gttatatcag ctcctgaagg aagtaaagct gttagctcct gtgctagctg acctagtcgc
    34681 gctttaccgt aaaggctgtc aaaatgcaaa gcccactcat ataagctgtc aatcattttg
    34741 aggtgcttag tgtatttggc agttagcttg ccagccttgg ttgtttgagc gtaaccctcc
    34801 atgtctgtga ggtctcgcag ctgatcagca gtgtcctgca tacaggctaa gagagcatct
    34861 acagcttggt ctggaatatc tgtaaagctg gtataggtct tagaccctcg taaaaagacc
    34921 tctgccaacc aactgctagg attggcagtt gattgactga aggcataaat gctatcaaca
    34981 atctctctaa aggctgagct atccttacga cgtccagaaa aattctgcac cagctgtata
    35041 aaggctttat tgtcagtctg cgacatatag tcttcaaaaa cctgacgaaa gacctcgcgc
    35101 tttaaaatgt cctgctctgc cttatcctgt atgatacgaa aatgcggtga aatccctaaa
    35161 acataaccat gctggtgaac caatttctga gcaaaggcat ccatcgtacc aatatcagcc
    35221 tgtgataaag cctgcaattg gtcattaagg taggccttga gctgataatc ctgagtctct
    35281 gctatagctg tgtgcagctt tttttcaatt ctctctatta gctcagtagc tgcttttacg
    35341 gtaaaggtcg aaataaataa gcaatcaacc ggaatacctc ttagaatctt atccaaaatg
    35401 cgctcaacca taacaaaggt cttacctgag ccagcagatg ctgatactaa gatattttgt
    35461 ccactgctat aaatagcctc aatctgctgc gctgtccgct tgtgcgtctt atctgataag
    35521 gcctcctcct gctgcaaacg agcaatagcc tctggcgtta gaaagccttc atcaatcctc
    35581 atgctttatc tcctcattca ttcgtgtcaa gaaagcctgt ctcctttctt ttgtcggtag
    35641 gacgactagg cgtctcgcgt accctagatc taaatccgcc tcaaagcgcg tgatggcctt
    35701 gagctggtca ccctgaacag acttgccgtc tgcggtataa gggtttatta ggaaatgccc
    35761 tgttttaatc tgcttcaccg cagacaaata tagctgctca ttataagcca gcagggtttc
    35821 tagctcatca gtctcataaa gtgtgttgtt aaggtgatag ctgccattag ccagatattc
    35881 cttggcttgg gctaaaaaaa tgcccttata ggttaactcc ttgtaagccg cagctactag
    35941 ctgatcatca agtgccttaa agtcagacag acttagcctt ggctcttgca tgtgcaggta
    36001 catggcgcca aacaggccct gccccttatt ctttagggca gcaagatagg tcacaagctg
    36061 aggactcaag ccattgtaaa aggcaacaat gtcaaatacc cttgcactgg atttgtagtc
    36121 cacaatgccc agcctaccat cagctagctg gtcaatacgg tcaataaccc ctcgaataag
    36181 cacttgctga cccagcgcta gctcaaaggc ctcctcttgc ttggttatct gcaggccttg
    36241 attaaggtct aagacagagg ctgttgagta agcaatcccc tttaggacct ctaagctata
    36301 tcgcccttca gcatcagcct gataaacctg ctgaaaagcg ctttgctgat taactgctgc
    36361 aatagctgcg cctagctttt ggtcaaaggc agcattagac ctatccttgg ttaccaactc
    36421 aaaaatacgg tgcaggtatt gaccatgaat gcgagcatct gggtgaatag actctggctc
    36481 ttgcagccct aggacatatt tcaagaaata cttgtattga ttgttataaa atacagtcaa
    36541 ggccgatgaa gacagattca agggctgctg acttgaaaag cgggtctcaa taacctcagg
    36601 tgctactggc ttagtagtca aatgatgctc aaaagctgga agacttagct gctcatcggc
    36661 tagcctacgt ttcaaataac gaagggcaac cgtccaaaag tttctgtcct cactggtcat
    36721 gtcatctgca attccctgcc gattaatagc caccaagcga gacaagagag ccttataatt
    36781 gccaatatct gccgctgagt gtgacaaacg gttctttcct ttttcaatga ctggaacacc
    36841 aagggcaatt agctccttca ggtaaggaga gacatcatct gagctattcg ttaagcttgt
    36901 aggcaggctt aacaccagct cctgcgtcgc tgcattaaac agggaaagtg ctgtttggtg
    36961 atttttcttg atattttcaa agctcggcac atcaaggcgc tggtaagagg cagtctgctc
    37021 attgatgctt gccctttcct gatcagagat caggctggtg ttttttgtct gcttaggaaa
    37081 atgggagcga ctcaggccaa tcgcaaacac aaagggcttg gaatgcggct ccaccagatc
    37141 ataggatttg atagacacaa catctaaggt cgcaggcact gtccgataat gtgctgtctg
    37201 catgcccatc ttgatcagag ctagacagtc tgcaagggtc attttttcct gaccaaacac
    37261 ctgataaaag gtctctaaaa tgcctgtgaa ggctttccaa acctcctcgt ccttttccct
    37321 atcagtctcc cttctactgc ctgctagtgc ctcaaaatta tcagccagct gaatggtctt
    37381 aaaaaaggtc attagcttat caagtaggga agcccctagc tgcttttgac tcttaaagag
    37441 ctgctggaga ggagtcacca cagcaagtcg cagctgattc aaaagaggca aaggatactg
    37501 acgtgaggaa tttagggtaa agggtcttga aaatttggtg aagccttgaa tatcagcaaa
    37561 gaccaagtat tgctcaagct gatccagctc tccctcttga aagcgcccaa agagtcctga
    37621 ttttagtaag ttgacaatat cctcacgtcg ccaattgtat ctgcggcctc tttctaagga
    37681 ttcgacaaat tgaaccaagg ggtgagcaga catcggctct tgcttgccga tataataagg
    37741 gatctcaaat ttctcaaaaa taggaccaat ttgcagctga taagacgcca catcacctaa
    37801 aaggacaagc atatccttat agcgataacc ctgatagagc ttctcacgaa tagcctttgc
    37861 aacatgctca agctcctctt tttgattgag cgcttgccag atcacaacct tgctcttgtc
    37921 cttggcactg agctgccaat caagctttga atagtcatga ttggcttcaa gaagctgtgt
    37981 taggcgagaa aatgacacat caaagacctt ttctgacgtt gtgtagatcg gcttggtttg
    38041 aaattgctgt gccagctgtt ggataaacgc aaggctcgcc tcgtagagat ttcccttggt
    38101 aaaggctagt cgataagcct tttgactgat ataggctcca ataacgattt cttcacaggc
    38161 ttcgtttaag agcgctagca gctgctcctc ctcagctgaa aagcgggtaa agccatcaat
    38221 cactaatacg gtctgcctta gctcgtcatc taggctcttg cttttgatag cctcagcaag
    38281 ctgagccagc ctacttgact ggtcgtaatc tccttgtgca atcagctgct cagccttggt
    38341 cataatcgtg atcaggtcct cttgcttttc tggtctatca agcgtcgtta agtcaaaggc
    38401 tgtcagatta gctgcttgca attccttata tagctcaact aactgggcaa taaaggcctg
    38461 atctgtccgt agccggtgaa aaacctttag ctcatcttct tgcagctgca tgagcacacg
    38521 ataaaaaatc atggctaagc cattatcatc taacgcttgt cgattagctg ccttagctaa
    38581 ggtaaaataa cgcgccatct gctcaaagcg ggtcaccgta atagcaaagg aaccctgctc
    38641 tggcaataag gctaggacag aacgttcctt ttcaaaggat agagagttag gagcaatata
    38701 aaagacacga tagcccttat cagcataagc tcttgcctct ttgactaaaa tctctgtcat
    38761 ggaatagcta atctctgtgt atagtaattt cataaaactc cttttatttg gacctgatac
    38821 aacgtctatg cctccattat aacaaatcag ccttgctttt cccattgtta atgatctttc
    38881 aaacgccaca agaagcgctc acagcatgaa aaaagcctac catttcacat ctgctgcttt
    38941 gcgcaagaaa tgataaggct ttgtcttgta taggctcaaa aaacagacta agagctccta
    39001 gttaagctgc cctgtgcttg tctcttgtga tctgtcccca ggcattcttt ttacgctgat
    39061 aaccaataaa gctgctcacc ttgataaggg ttaataccgt atgaagaaca aggcattggt
    39121 agatggcagc atagattacc caagccatat caaaaagagt aatgctacta ttgttttgca
    39181 aataaaccct atttaaaaac gatgtcaacg caataagcac acaatagcaa atatagagca
    39241 gcatcagtga cacaaaaaag gttgtgttta attgatggca tagcaaagac agcacaatga
    39301 taataacacc aaatgcctca ataaaaggag ataaaagctc aaacaaaaga tacagcacat
    39361 aggaaatgag taccgtcgct ttaaaccgac agcttacaaa aaactggaga tactttttca
    39421 agcattgata cagtcctaaa aaccaacgac gcctttgccg acacaaatcc ttcaagcgac
    39481 tgggcgcttg gctccagcaa atagcgtctg tttcatagcc aatacgataa ggaatcttgt
    39541 tgttatggca gaaaaaatgt aatttcatca ccagctccat atcttctccc agagtcccag
    39601 tgtcataacc atcaacagca atcgcaagct cttttttaaa cagtccaaac gctcctgata
    39661 tgattaaatt cccagcagcc tggtctaata aaacacgagc tccaaaaaag gcacaatcat
    39721 actcaattgc ctgcgcacac gaaataagct gacgcggcaa atggtagtct acgatcctcc
    39781 cagctgccaa tgctactccc tgcgaaacct tgaccatgcc cccaacagca atgacagacg
    39841 gatcctttgc agcagtcttt gcaatacgct taagcgaatc ctcctgtagc atcgaatcag
    39901 cgtccatgca caataaataa tcgtattgag cagcgttaat cccaagattg aggctatctc
    39961 ctttgccgcc atttgccttt tcaagcaggg tcagcttgat atgcttgagc tgcttttggc
    40021 ttacagcctt tagagggcgt gttgggatcc gctgattaat cgaacaagtc accgcttcta
    40081 aatgaaactg ctccttcaag agcttggcgg tatgatctgt tgacccatca tcaatgacaa
    40141 taatctcata gcagtcataa tcaagcatca gcaaggactc cactgtttcg ataatggtta
    40201 gctcttcatt ataggccgga accaaaatag acactggcgg taaagaaaca tcaccaccaa
    40261 caggcgcttg ctgtcgcctt tcataaaggt gaatagtccc aacaattaag gatagcagta
    40321 aaaagctcgc ataggcaatc aaaaacgcta aaaaaagata ttgggagtat ttcaatacta
    40381 aaaacagtag ctgcactatc attctccttt aacatgcaat cacttgtgct taccattcgc
    40441 cttacaaaag cgtctcaagg tctgcttcat caaatacccg atattaaagg caaggatcgc
    40501 taagcaaacg attatataaa aaaacaacag gtaataaatc atcttatctt ctcctctttt
    40561 cctgccagac agcctgcacc tgctgatagg aggtctttaa aacttctctt acccttggac
    40621 gctcccagct caacagtgga tactctacca ttgcaatgac ctttgattcc tttagcggtg
    40681 caaaaccaat agctattgct tcaatggcta attcctcaac accatagtgc tcaaaataat
    40741 catcgtgtat tttgtttgaa gctggatcag aaaaattgag cagctgccag ggaatcctaa
    40801 gctcaatcag acgctcgcca aaagaaatat cggtctgcga atcaaaatga gccgagcctc
    40861 gtttgccatt gccctgtttt aattggccgg tagggtagcg cttcagtcct ctttttgcaa
    40921 tcggaacctg atcaatggct gcaaaaatac catcatttct caccaccata tcaaccatag
    40981 taaatcttgg cgtatgcttg ttagggggaa agacataaaa gtcctttcca ttaatctgcc
    41041 taaggtaatt ggcatcagta gcatggtagc gctcctgcac caagaggcga ctgcctttgt
    41101 ggtcatcaac aacaagggca aaatcagcaa agcgatcaaa ccgagcgcta aagccttcaa
    41161 taaccctgct gcctgttttg ggcgtaatgt ctaagggaat gagccactgt ctttgtaagg
    41221 gctgcttttt tgtcgattca atagcaatat agaggtattt ttcgtcctga tcaacgagga
    41281 gctgctgccc atttttcttg taggttagag ctctagacca ctcatctgct gccttttgcc
    41341 catcaatagc atgcgtcctt ggagcatgct caaaggttaa gagaccataa ccttgagcct
    41401 tagactgaac atcaccccaa agaaagcttt gatgtttatt ggttgcaaag gaggtattcc
    41461 agctcctagc agtccaatcg tcctgccagc tatggatcgt tgcaccacag cagccagacg
    41521 caataaaggc tgtgtaatct gccatcaagc gctcgccttg atccttttct gtcaaagggc
    41581 tggaagtcga tatcatttgg tccacacctc tggctgtcga atagccatag cccgtcacaa
    41641 ccactgggac acgatgatag ctcgtcagta gcttgacgta tccctgatat aagggcatgc
    41701 gcttaatatc cccaacaagc ctatcagtaa gccctagacg gtcaaatagc agataatccc
    41761 tataagccga gtgacaatcc aagagcttat aggaagcaaa aagaccggcc ttaaccttag
    41821 cgctgggctt aatattttca atcgtcagtt gaacatattt tgctgcctga gaggcaaagg
    41881 gatcctgata gacaaaggga tctgattgag gcgtatttga aaagctcacc aagtgctgcc
    41941 agccatattt gcggctctcg tatgacgtga tttcctccat gatttcagcc agtatagcct
    42001 caaaccgatt ggcctgaggt gtcgttgcat aataccttcc cttaaagcct acaggcttgg
    42061 cgtgattctg atgattggta taggctatcg tcccactgta ccaatcatca ccaacaatat
    42121 agccgagtag ccatttactc atatcctgat cataatgctg aagccctaaa tccgaatgcc
    42181 agatccgttt tctcccatga atcacatcaa cactagccct agcttccctt aacagagtgc
    42241 ctaaataagc cttatctaag gcgctgatag aagaattgtc atgataagca tctattctaa
    42301 agccctgtaa taggtacaga ggatgacttg ctctgtcatt gtagcgtctc aaagcatggt
    42361 aaaaagtgac gggcataata acccttaccc tgatcgtatt tgcacccata gctgctattt
    42421 gcttgaacca cctatagtag gttttctcat caacgctaag gtctcgtcga cgatagcctg
    42481 ctatggaact ctccacatca acacccttga tgagataagg agatcccttt tgatcatata
    42541 tgcgcttgtc cttggtgtaa aagactgtcc gaatagctga ctggttagag accggcaggt
    42601 acaagcgacc atcaatatca caacaataat agctcaagcc aatcacagac aagagcaaac
    42661 caacaaagat taaatatttc ttcatcacta cctactccaa taatgtattg gtatttttag
    42721 acggtgcact gtactgatag agcgtctcaa tatgcttatc cagccatcgc ccacgacgtc
    42781 taataaagtc ctttagttgc ttaacagagg cctcatagct actgtagtta cgactggctg
    42841 gcacaaggta attagtggca tcgcttcttg atggcactgt aaacacatag ccccacttat
    42901 gataattgcg ctgaatagcc ggacctaaaa aagcaaccgt agcatcaata tacttgatca
    42961 aataatccgt tgataaaaca ttctgtcgga gctgatgata ccttgtgacc accagcttaa
    43021 caaagctagg atcctttagc agcatgcaaa accaaggagc atctgatagg gtaaagtccg
    43081 cctcatcata aggagcctca atctgattat caaaggcgtt gttaaaatcc cagaccacca
    43141 gcttgagctt atcgcgcaaa tccttataaa gataggttga aaacttccca gcatcaatat
    43201 ttctaaagaa ttcattgata ataaaatagt ctgcaaagga ctcttggtcc agataatcag
    43261 tgtattgctt taaatcataa gaatatagga gcttttcgat atgactgata tccttttcaa
    43321 taaactgctt ttgcttaggc gtcagacggt gcaggcttgg gtatttaatg tctaaagagg
    43381 acagacctgc ttgattcgta taggatacgt aatgatcaag agcctgctta gccttgtgtc
    43441 ttctatccca aacaaggata taaggcgttt tatcagattt tctatcactt ttttcgatgt
    43501 ttaccctatg ccgcccctgc tcaatactct ccacagccaa atacagacca caatactgat
    43561 gatccaccac taactcgcaa tacctgacgt taggtgcata ggtcatgatc tcaccggcaa
    43621 tattgtagct aagataattt cggactaggg tccgatctaa aaaaggacca tgcagcaccc
    43681 actcagactc cttggacatg ccagccagcg agactgcctt tggcttagct cttttattga
    43741 taaaccttag ctttaaggat ttcttgtcaa aatgacgtga cgaattgccc ctataagcaa
    43801 tcaatgctgt caaggacaag cgcggagact cagacaggct gtgctctcta tctagctgat
    43861 cacgaagcga gaccgtcgtt ttaatggttt tttgccgctt tgtctctccc tcgtattccc
    43921 tttgctctgg aatctgctga tgatgagtgt caatgctaat aatcggcaaa tgagagctaa
    43981 actccccagt gcttctggag ctctttttga ccgtctgcaa atggtgatga atacgctttg
    44041 cagaggtctt aggaaaaccg ataccacaaa tagcagctag caagagacac accagcacaa
    44101 tcacataaat cgtcttttct ttcatttacg tcaaccagtt atgtcatcgc tttgactaac
    44161 aatattaaaa taatcaactc gccccagctg ataaacagcc tcagttaacg gattagcctg
    44221 ctgataggtg ctgtcataat cctttcttga cagctcaaag atcatctcaa tatcatcaga
    44281 cgtggtgttt ttcacgctct ggatcgcctt acccgaaaag tagttaaaca ctaaccgctc
    44341 cagctcaatt tccatttgct tatcacagcg aacaatcaac aacagtctat tgtcatttct
    44401 gacagctccc ataagcaaca aaagcataaa gatcacgctg ctaccagttg cagcgacagt
    44461 ataatcacca acaccacagc aaatcccaac cacaatcgtc caaaaaatat agactgtatc
    44521 tctagagtct ttgattgctg tccgaaaacg cacaaccgac agcgcaccga ccataccaag
    44581 agacaaagca acattatttc cgataactgt catgacggtt gctgttaaga ccgtcaaggt
    44641 catcaacgaa acattaaact tcttgctata ggcagtccca gtgtgggtat aggcatatga
    44701 catataaatc acaatactta acaaggctgc agcaacaata tgcagcaaaa catcttgaaa
    44761 gctcaaggtc ccacgctgtt caaagacatg tcttaataat tgtttcatct taatatctct
    44821 cctaaaaacg ataatgcttg ctgatagctc tccccatgca atacttgctt gcacttagct
    44881 cgctaccatt aacagactcc aaaagctttt tgatataaga caacaaaaag ccattatact
    44941 tgacctccaa gatgaccaaa tagggatcta gcaggtaatt ctgaggcaga tgatctgaaa
    45001 aaatatcagc attggtctca gacccgataa tatgatgatc aaaggtaatg cgaatattgt
    45061 tttcctttgc cacaaatgcc ttgcgctggt attcgatcac tgtttttggc tgatagagct
    45121 gcattgacat gcgactatag cattcagcag caaagcgatc aggataagtc agcaatatag
    45181 acttgtctcc cttaatcaac aattgagcgt ctgctctggt caacctcaga gatcgctttt
    45241 tttgattgct cccttgcttt tgcttcatct ccaacttagc aaatgagctc tgactaccgt
    45301 aattgcgcag gcgaattttt cgcctaagct caataccgtc ctctttttcc tgccagtcaa
    45361 cgtcctccaa agaatcaaaa tacaaggatc gaatcacata tccctcacta gagctatgag
    45421 catctagacg caagagcttg gaaaattcat gcgataagcg ataataatcc tcaatggtaa
    45481 tcaaatactt tttttcttga cgcaatacct cattcacgcc agtgtcctcc tttttcgtct
    45541 gtaagcaatg ccttaacacc aagctgcctg taacagcagc caacaaacct gtctcataaa
    45601 taagtcaggg caaataaggt gattgttggc tctacaagag tcaatcacct gccaaaatag
    45661 taaatcctgc catctgttga aataatataa accagctgat cgtcttgatt gcaagacagg
    45721 cgcttttgtg actgatctag ctgtctgctg ctaatatcag ttgcattagc ctccttgagc
    45781 atggcctgct tgagctgttg ctggattttt ctggcttgca gctcagaaat ctcaaagctg
    45841 ccattaacct tttgagcctt gtgcttgtag accagtgcca catggtcttt agctgttgtc
    45901 ctagcagtcg acaggagccc ttctttgttg agctgagtat gctctcctac atcaatggca
    45961 acatagtcat agggtgcccg tatccggtgc gctgttagta ttgaggacaa aatccctgtc
    46021 acaaggcaga tgcttatcgt agccactatc atctgctgcc gctgcttacg aatgaacctt
    46081 gaaaaagcac agacctccgc ctgatattcc tgaagctctt cttcaacctt actgtaatcc
    46141 tgtctaagat cagccaagtc agtctgacag tccttgcagc ttgtcagatg agcctcaaca
    46201 accgctctac tataatcact caacgtatca tctacatata atggcaacaa atcctggatc
    46261 aactcacaat catacttcat agccatactc ctctcgtaat tgtcttttaa tatgttttct
    46321 tgccctaaag acaagaacct tggcagagga tactgtgatg ccaatatcct tagctatttt
    46381 ttcataggaa tctcccgaat aaatcctcgc cagaaagaca gcctgcattt tctctggaag
    46441 attaaaaata atcgttagtg taatctctaa cagctccctt cttgctatct tatcaagtgg
    46501 ttcatcatgc cctttagcat caacgatttc taagctttcc atcgacatat tctcatattt
    46561 tttcttttta atttctgtaa agaaggtgtt ctttgcaatg gtaaataacc atgttttgat
    46621 tgaactatcc ccactaaatt tagcaatatt acgataagcc tttagaaaag tctcttgagt
    46681 aatatcatct gataaactat tttgataaca gcacagctta tttacaaacc tataaacatc
    46741 atctttatat tctaaatata tgtcctcaaa ttccaacagc ttgtctcctc tcaatacacc
    46801 cttaaccatt agaccgtcca atctgccaaa agttacagat taatttaatt tttagtataa
    46861 gctgtcatca agtcagataa atagtaatga tctatcatct tattattgac tcaaacgaca
    46921 aattatattg cattttagta taagctgtca tcaagtcagg taaataacaa ggacatatca
    46981 tctaacattt gatccagaca aaaaagacct gattctgtaa tatacagaac caagtctttc
    47041 tcaatagaca ttgactagat gattgattta tagcgacata gctagatagg ctatgactta
    47101 ccgtcttttg gatttggaga caagcccgcc aagacctgcc aagataccac tgccagcaag
    47161 agccaataaa gcatctagct gactagtgcc tgttttaggg agagtcttag ctgagaactg
    47221 agaaacctct ccagcagtct gagcagcaac taatttctcc tgatgatggg ctgcttgatc
    47281 agtcattgca cctaaagtcc ccttatcaga ctgggacgcc ctaagacgga taatggtagc
    47341 tgttaagcct gatagcttga ccccgtcctt ggttagcaca accccctcag gacttgccag
    47401 cgcctcggtg cctgcttgct tggcatcgac gataacctca ccagcaagaa gagcctgaaa
    47461 ctcaccagtt agcctaatgg tacggtcatt gctatcagca ttgacaaaga cagcataaac
    47521 atcaccattg cttgctgttg tctgataagc aatcaccaaa tcctgtgcct tgatcccatg
    47581 ctcatttgga acagtgatca gcttgacctt ctggtctatc tcagccttac ttgccaagcg
    47641 aaaggcatct gtcgaacggc gcagcgcaat caatccctta gtaaaggcct gacttgtcgt
    47701 gctttcaggg tagcgctctg tatccgttgc ctttgcccag tcaaaatgat taatggcatc
    47761 tgtcgaatca taggaatcat gaataaagta tgggtattca aatggtgttc cgtcctcatt
    47821 gaccaagagg tgtgatttat ttggcacctt gtcatcagcg accttgccct tataggcttc
    47881 gtccttaaat tgctttgtac gaccatattc ctgaccagca tgtaggaaag gggtgccttg
    47941 agaggttagc accaagaggt tccctaggcg caagcgacga tgaatctctg ccgcatttgc
    48001 tgcaacagac ggatcctttt taatagactg ggcgataata tcaaacaagg tcaggttatc
    48061 atgtgcagcg atatactgaa tcacatcacc cggatcatca gccaaaaagt tagtcggctg
    48121 agccttgata ttatgaaaaa tggtcatgat atccctagca ccgcccgtaa taaaggctgg
    48181 agagccttca tttggaaagc ctgatttgag ctgattgcga aaatcatctg agaaggaggc
    48241 aacggtatct gtctgtgaca tccagctttg gtccgcaggc tgctcaggca tgtgctcatc
    48301 accctgatag gtgacccagc cctcaccaag catgatgata ttcggattaa gtgccttagc
    48361 tgctaaaaag gctttttcaa tagctgctgc atcatggtcc cccatcatgt caaaacgaaa
    48421 accatcaacc ttatactcat ccaccagata agtaatcgaa tccaccaaaa cacgacgact
    48481 catgtaatgc gttgtcccaa gtcgtccacc accaaatgag gtcctagcag tgccatcagc
    48541 attcataaag tgataataat tcggctccag gtcctcaaaa atatcaacat tagctgtatg
    48601 attgtagacc acatcaagga taacccccat accacgctta tggatttcat taacaagctg
    48661 cttaaattcc tcaatgcgct tagctgggtc ggttggatca gtcgaataca taccagtcaa
    48721 ggcaaaatag ctttgtggat catagcccca gttgtaatta ttatcacttg agctgtaggt
    48781 cagcatacgc tccttgttgg ccaattcgtt gacaaaataa tagctcatca caggcagcag
    48841 ttgaacatgc gtaataccaa gctccttgag ataatccaac ttttcaacaa aggcagcaaa
    48901 agtcccaaat tgagccttta gatcattagc aatcgcctga tctgaggtaa aatcacgaac
    48961 atgtgcctca tagataatgg cgtcctcacg cttatgaaag cccttaatat cagcaaaggc
    49021 cagctcctta tccccaatag cagcaggatc aacaatggcc gccttagcca ccttatagga
    49081 cgggtctgtc ttagcaagct cgctgttcca tgccgctaac gatttggcat aagggtccag
    49141 cacaaggaca gacttgccat ttctagtaat ctcataatga tagaaatagc ctctataatc
    49201 tgaaatccca agtccgctat ctgctgatag agtgattgac cactctccct tatcaccctt
    49261 tgctagagcg agattaccaa tcaccttggt ctgatcagcc ttatcataca aaacaagtga
    49321 caccttatca gcacttggtg accaaatcgt cagatcaacc ttagcacctg cttctctcac
    49381 acgcgctcct agctcaccgt cataagcata caggctatcc ttgtattgcc aatttggcct
    49441 agcctggaag ctctcatgat gaaaggtcac cgtataagtg gccactgctt gactaaaatc
    49501 acctgtgatg acagccttat gagtcttttc atctaaggtg atatcagtaa tagcaactgc
    49561 ttccttactg tcagtgctga tttttaattc ttttaaaagg ctttccttat ccacatctgc
    49621 tagagtcgta aagctcgcct caatactgct tgggctgacc tgctgagcac cgattaatct
    49681 aactgtatta acaaaataag ggttcgtata aatggttgga tcctcgtctt tcaagaaaat
    49741 ttgggtgtga ttctttaaat ctttaaaaat ataatcattg ggctgaattt taacagcgtc
    49801 acctgtctga cgctcatcta gcaagagaaa gcctagctca ttggtatcag ctagcttgac
    49861 atctatataa gcaccatatc gaccgacctg cttaaaatca ataccatctg gccaagcgcc
    49921 ctgctgacta gtcattgacg catcagcact tccccaaagc cagagcgatt tgttgtcata
    49981 atggccatca ctgcgataat aattgatacg gatatagccc tgagccagcg gccgatagta
    50041 agacagctcc tggccatcaa tccagacctc attcatctta gggctgagaa ggtctatggt
    50101 tcgatcgccc gtcagattgt ctcccttagt gttattgatc aaaaagctaa ccttattggc
    50161 ttgattggct gaaagcttaa cgtccatgta atagccatag tcatctgtct tcgctagact
    50221 aaaattggta gccccagtcg gccagcctcc cagctgatca gatggtgtct caacatcgtc
    50281 ccacacccaa agaccaagcg aggataggtc ttgagctggc agggtcttga aatgcagccg
    50341 caaggtctgc tccgctatcg gctcctctga gcttgtagct tctggtgtct ctagagagct
    50401 gtctgtcgta acagacacta tcgatgatga aggctgagac tggtctgtag tttcctcatg
    50461 cgcctgatcc tctacaagag gtacagctac tggctgaact tccttgacag tatcagcatt
    50521 gacagcagct gacaccttag tcacatcaga aataccagca atatcactaa tgtcagtagc
    50581 ttctggtagc tcatttgagc cttggtcagc agcctctgac ttgaccatga ccgcaccatc
    50641 agcaggctca acactcgtca gactctcagc tgctgctgtg atctgcccac tagctgtccc
    50701 caaagaaaaa gcggttgcaa tagctaccga agccactcca agcttaagct tacgaatgcc
    50761 aaataattga cgctcttcaa acagcgcttg attttccctt aaccttttca tcattcctcc
    50821 gtccttatcc tgatagttat taacacctta agtatacaaa agaaatcaca atagtgcaat
    50881 cgttttcttt attgaaaaca atgatattta tgaacaaatt agacaagaat caacgcaagc
    50941 gatttcctta ctgataaata cctgctcccc tcactaagac cagcccactg caaagcagaa
    51001 aagtagccta aagagcctta gtaacagata aatgagctta atgttgcttc atcaactagc
    51061 tggctgcaac cgttttgctc tgatgtggta acgtcttgtc atcatgacta agcttgacaa
    51121 aaaacgctgt tagttacata atcaacggtg cttggtagcc ttccattact cctttgattg
    51181 ttatacccta atgatacaca aaacctcagt ttttatagta gaatattaca ctttgttttg
    51241 acaaagatgt ttaatcttgc taaaataaac ttatcaatga gggagtacca atgatgacat
    51301 tcgaattcac atcgttattc gatttacaaa ctgcttttcc aacagagcag gcttgcataa
    51361 atcatttaga aaatatcact tggggtgacg tggtgatcag cccttttgac gctacctcaa
    51421 aggtctataa atgcaaggga aataaatacc gttgcaagaa tacagggaag tatttcactg
    51481 tcaaaacagg tactcttttt gataatacta agattaagct acaaaaatgg tttatggcaa
    51541 tctggcttgt gacttctcac aagagaggaa tctcctcagt gcaattatca aaagagattg
    51601 cagtgacaca aaaaacagca tggttcatgt tacagcgtat tcgtaaatgc tttggctctg
    51661 aaaactgaga tccacttggt gacgtcgttg aagtagataa aactgatatt gatggtaaaa
    51721 ataagaacca ccatgatcct aagaaggcaa aaacgttcaa gaaccatcct tctctgaaag
    51781 ataagtcggc agttattgga atggtgcaac aaaaaagtaa ggccaacgct catacaatac
    51841 tcgtgattac tctgatagtc ggcgttttat cttttatcag ctaatgctga tatgcgaaca
    51901 acttataagg agctgatcaa tggttaaaca tgcaaaaact aacctacact ttgaattaga
    51961 aagatctatc tctcgcaaag ttgatagtaa attgatagcc tatcaagtca gtctttcaga
    52021 tggcttttat gacaaataca ccaaattatg ggataaaacc tattcatttg attttgtcat
    52081 caaccatcgt gcgttttatg ctcagttgac caaaagatgt gtttacgatg tccttttgca
    52141 aactttggaa aaaatcagta gaaaagccat tgcaaagcaa ctagcagagc ttgaagcctt
    52201 ggttgatgtt tcggaaagta aggaagactt tcagatattt ttcgagaaaa aatacaaact
    52261 atcatttcct gatttgaaga attgtgttta tccaaagaaa aaggaacttt ccgattttga
    52321 tcaaaacctc tggatagctc tacattataa ccctagaaag gagagggata cataatgaca
    52381 acatggtatg attacatggt aagagccagc gaacactctg gaagtgatgg agacctctgg
    52441 tttcgttacc tttacaaggt tatcaaagac aaagaaacca aactaactac tgatgatgtg
    52501 gagcagttat taaaaaatcc gaatctaact ccttttcaga aggtaactct gcaagatgct
    52561 ttaacagaag gtacgcatac aagagagcat gttttacagg caaaccgtaa aagtcagcca
    52621 aaggatattt tgaaactctt tagagaggga aactatggat aaaaaaatct tattcaaagc
    52681 tctgaataca gaactagcta aagaaaatat tagccttgac attatctgtg tcggtggttt
    52741 tgtccttgaa tattacaatc tgcgaggaac acaagatatc gatgcctttt atcaagaagg
    52801 tgttaacatc aggcagatga tcaaaaaggt gggagatgag tttggcgtta atgaacctga
    52861 tgagctttgg cttaataatt cagttgccaa tcttaataga ataccaccta aaacgatttg
    52921 tgagacagta tttcactatt ctaacctaat tgtccttgtc ccacccttgt cttatattct
    52981 tggaatgaag ctagaaagcg gacgagatag ggatagacaa gatgccggag acattattaa
    53041 gctagctaat atccgttccc ctaaaaaact tatcaataca cttgaagagt atgattttca
    53101 acctgatatt tcaatgattt tagaagtctt tgaaatagct tatggcatgg aatggttagc
    53161 aaactatatg accgaacacc cagaagaatt taggcattat taaaagacga tttctgtttg
    53221 gaagtcgcct tttttgatgt ttttgaaaac accttgagat tagtctaaac taatctccat
    53281 aagcaaaaaa cagcttagcc ccgtctggga gtaagctgtt tttgctgtaa tgtatgagat
    53341 aattaggcta acatcaatca ttacataaag ggaataaagg gttaatgttt cttgcgtttg
    53401 cgtgatacta cagctacgcc tagacttgcc aatacggcaa gggctgctgc tgtaaagaat
    53461 ggagctgttg cttctcctgt tgacggaagc ttgtgttcca ttgctttagg taccgctggt
    53521 ttatctcctt tctgtgcttc
//
LOCUS       DARYNN010000007        51519 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.007, whole genome shotgun sequence.
ACCESSION   DARYNN010000007 DARYNN010000000
VERSION     DARYNN010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 51519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51519
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.007"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            145..759
                     /locus_tag="TVB59_000359"
                     /pseudo
     CDS             145..759
                     /locus_tag="TVB59_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677880.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            1289..2167
                     /gene="mvk"
                     /locus_tag="TVB59_000360"
     CDS             1289..2167
                     /gene="mvk"
                     /locus_tag="TVB59_000360"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEL1009302.1"
                     /translation="MNKTIGYGKAHSKIILMGEHSVVYGYPALALPLKDIEVTCRIFP
                     AAKPLAFDFYDPLSTAVYAALEHLGCLAEPIHYDIMSQVPQKRGMGSSAAVSIAAVRA
                     VFSYFGQPLSDELLEILVNKAEIIAHTNPSGLDAKTCLSDKAIKFIRNVGFDTIDIQL
                     NAYLVIADTGIQGHTREAVNKVAQFEEENLPHLAKLGCFTEAVEQAIKTNDCLAIGRF
                     MTQAHESLKAIGVSVAKADQLVAAALEAGALGAKMTGGGLGGCMIALAERITDAQQIS
                     KKLKEEGAVNTWIQIL"
     gene            2149..3093
                     /gene="mvaD"
                     /locus_tag="TVB59_000361"
     CDS             2149..3093
                     /gene="mvaD"
                     /locus_tag="TVB59_000361"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEL1009303.1"
                     /translation="MDSNTVTVTSYANIAIVKYWGKKDEAKMIPSTSSISLTLEGMYT
                     TTSLSFLPASAKGDQFYINGVLQDAKEHAKITAILDQFRQKDQTFVKVEASNSMPTAA
                     GLSSSSSGLSALVKACNQLFQAKLSQEELAQKAKFASGSASRSFFGPVAAWDKDTGSI
                     YKVKTDLKLAMIMLVLNDARKPISSREGMKRCSTTSTSFDQWLAQSESDYQAMLRALS
                     DNDFETVGWLTEANALAMHATTKTASPSFSYLTEASYQAMLRVKELRQEGYSCYFTMD
                     AGPNVKVLCLEEDLERLSHLFEREYRIIASKTKELPDV"
     gene            3086..4084
                     /locus_tag="TVB59_000362"
     CDS             3086..4084
                     /locus_tag="TVB59_000362"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEL1009304.1"
                     /translation="MSKYHVQAGGKLYLTGEYAILRPGQTALICYIPIMLTAVIEAAE
                     AVSISSDMFDHAADLSPDKDYRLIQASIEAFSLYIDKDIKELPAFSLSITGKLERDGK
                     KFGIGSSGSVVVLTLRALAAFYQVQLLPEQLFKLAAYTLLKSGDNGSMGDIACIAYES
                     LVAYTSFDRRKVGQWLIEMTLKELMAAHWGYTIETIEPALPCWFLVGWTQVPSISREM
                     IQLVNKSISCQFLEQSQLVTQEVMTALQLGQRKRLKASIEKAGQLLQGLASVIYHPKL
                     TQLVQACQGLDAAAKSSGSGGGDCGIALVFEAKDIEPILARWQQAGIVLLYQEEWG"
     gene            4087..5079
                     /locus_tag="TVB59_000363"
     CDS             4087..5079
                     /locus_tag="TVB59_000363"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEL1009305.1"
                     /translation="MTNRKDDHITHALSYHSPYNAFDDMELIHCSLPSYDLADIDLST
                     HFAGCDFEFPFYINAMTGGSKKGQAVNEKLAKVAAATGILMVTGSYSAALKNPEDTSF
                     QLRGVAPDLQLATNIGLDKAVDLGIRAVEEMKPLFLQVHVNAMQELLMPEGERSFKHW
                     KDHLAAYAKQLPVPLILKEVGFGMDIKTITIARDMGVKTFDISGRGGTSFAYIENQRG
                     SNRSYLDDWGQTTVQCLLNAKGLVDEVEILASGGVRHPLDMVKCLVLGARAVGLSRVV
                     LELVETYPVEQIIATINSWKKELKLIMCALDCRTLSDLRQVDYLLYGRLYQANR"
     gene            complement(5364..6647)
                     /locus_tag="TVB59_000364"
     CDS             complement(5364..6647)
                     /locus_tag="TVB59_000364"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEL1009306.1"
                     /translation="MTKTKPNWAGFYKKSLAERIQQLADDQLLGPQQQKLLETDQLLP
                     IAIANQMTENVIGRLALPFSLAPDFLINGHTYQVPFVTEEPSVVAAASFAAKIIKRSG
                     GFQTEVLSRQMLGQVALYDVKDDEQARLAILANADTLIDVANNAYPSIVKRGGGAKSL
                     TVERKEDFFIVYLSVDTQEAMGANIVNTMMEALVPDLEALSGGQCLMAILSNYATKAL
                     VSAKCQVDLRYLSRHKEEAQQLAKKIELASKLAQIDPYRAATHNKGIFNGIDAVAIAT
                     GNDWRAIEAGAHAYAARTGSYRGLSSWHVDLSKNSLCGELTLPMPIASKGGSIGLNPT
                     VSVAHSLLEQPNAKVLAQITTAVGLAQNFAALKALTSTGIQAGHMKLQAKSLALLAGA
                     SEQEVPQLVKALLKDKPMNLEKAGQLLTAIRLSQS"
     gene            complement(6634..7809)
                     /locus_tag="TVB59_000365"
     CDS             complement(6634..7809)
                     /locus_tag="TVB59_000365"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEL1009307.1"
                     /translation="MNIGIDKIGFATSQYVLKMEDLALARSTDPAKFHQGLMLDALSI
                     APVTEDIVTLAASAADQILTKDDKASIDMVILATESSIDQSKAASIYVHQLLDIQPFA
                     RSFEIKEACYSATAALDYAKLHVAAHPASKVLVIASDIAKYGIGSAGEPTQGAGSIAM
                     LVTTNPRILQLNHDNVAQTRDVMDFWRPNYSSTPFVNGIYSTKQYLDSLKTTWDKYQE
                     KEGIELSDLAAVCFHIPFPKLALKGLHKIMTKSLADDHKERLYENFQASIAYSKQIGN
                     IYTGSLYLGLLSLLENSQVLRAGDRIGLFSYGSGAVSELFSGQLVDGYKDMLLTNRQA
                     LLDQRQVISVADYEALFYEEPRLDQDGNASFSPYLTGRFALKEIKEHQRIYQDDDKN"
     gene            7994..8833
                     /locus_tag="TVB59_000366"
     CDS             7994..8833
                     /locus_tag="TVB59_000366"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEL1009308.1"
                     /translation="MTKADHIFKANIKKIMEEGVFSEQARPRYKNGQTANSKYITGAF
                     AEYDLSKGEFPITTLRSIPIKSAIKELFWIYQDQSNSLDVLENKYNVHYWNEWEVGQT
                     RTIGQRYGAIVKKHDIISKILKQLEDNPWNRRNVISLWDYEAFEESEGLLPCAFQVMF
                     DVRRVDGELYLDATLTQRSNDMLVAHHINAMQYVALQLMIAKHFGWKAGKFFYFVNNL
                     HIYDNQFAQAKELLERQPAACQPKLLLHVPDGTDFFDIRPEDFELQDYYPVKPQLTFD
                     LAI"
     gene            8914..9411
                     /locus_tag="TVB59_000367"
     CDS             8914..9411
                     /locus_tag="TVB59_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEL1009309.1"
                     /translation="MTKKIIAIWAEDEAGLIGACGRLPWYLPKELQHFKETTLNQAIL
                     MGRVTFEGMKGRLLPNRQTLVMTRDSYYHVEGALTITSVQEALDWYHAQDKTLYVIGG
                     SKVLEAFDGYFDVIIKTVVHHQFEGDTYRPRLELSDFVEETSVLYPRDDNNPYDFTVT
                     VLRHR"
     gene            9431..9601
                     /locus_tag="TVB59_000368"
     CDS             9431..9601
                     /locus_tag="TVB59_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009310.1"
                     /translation="MQRSIFGVFTAFLCAICVLCAIPAFRKNRYGLGLLFLLNAFTNL
                     VNTIHAFYGTLF"
     gene            9637..10866
                     /gene="clpX"
                     /locus_tag="TVB59_000369"
     CDS             9637..10866
                     /gene="clpX"
                     /locus_tag="TVB59_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEL1009311.1"
                     /translation="MAGNRSNDIKVHCSFCGKSQDEVKKIIAGNNVFICNECVALSQE
                     IIKEELAEEVLADLTEVPKPKELLEILNQYVIGQERAKRALSVAVYNHYKRISFTESR
                     DDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTV
                     ASVPPQGGRKHPNQEMVQIDTKNILFIVGGAFDGIEEIVKQRLGEKIIGFGQNSRKID
                     DNASYMQEIIAEDIQKFGLIPEFIGRLPVVAALEQLNTEDLIRILTEPRNALVKQYQA
                     LLSYDGVELEFEKGALEAIAGRAIERKTGARGLRSIIEETMLDIMFEVPSQEEVIKVR
                     ITKEAVEGQSKPILEIA"
     gene            10876..11475
                     /locus_tag="TVB59_000370"
     CDS             10876..11475
                     /locus_tag="TVB59_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEL1009312.1"
                     /translation="MSEEQILNTHNASILLSAANKSHYPQDDLPEIALAGRSNVGKSS
                     FINTILGRKSLARTSSKPGKTQLLNFFNVDDKLRLVDVPGYGYAKVSKAERARWGKMI
                     EEYLTTRQNLRAVVSLVDFRHESSQDDIQMYEFLKYYEIPVIIVATKADKVPRGRWNK
                     HESMVKKSLNFDQTDAFIIFSSVERIGIDESWDTILEYL"
     gene            11839..14841
                     /locus_tag="TVB59_000371"
     CDS             11839..14841
                     /locus_tag="TVB59_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-rich repeat domain-containing protein"
                     /protein_id="HEL1009313.1"
                     /translation="MTIKKCPQILALFLAFAALASQGQTVHALERQETSVKQAHESDD
                     WFDEDEGVSDIKSNTPTEIDSTVTELFGDAEPKTKAEKEESKAPSPKQEALPAESQKE
                     KETSAKSTDHATVQAEEAQPEQGSDSPWLADDFVTKGDTLVGLSKAGLAKLSKTPVLV
                     LPRIGIDKTVLTRIASFAFTPNKSVAIADYTGRAGEHGEINHLDVEGRDILTEGEDFG
                     AYAIKKLVIPEGYLFIGQDAFNDNKQLEEISLPDSLLSISDYAFAHMSLSKLKLPKSL
                     QSIGDQAFFDNRIAGTLVLPKALKQLGERVFKSNRLTGLVFEGEGLSVLKEAAFQDNA
                     FISLVIPDSIQALEEDVFTGNLGDEEYGNHAVLRTKNGQNPYRLHSANVLVNPSDQAR
                     TPQPPIDYNRWLAEDFTYTGQTITGFSASGLRKVKRNKHLVLPKNYQGQPLTAIADNA
                     FRNVNFHDKTLRKYDLESVTLPSTIQKIGAFAFQSNNLESFEASEDLVEIGQGAFMNN
                     RIEILALNDKLKVIGDAAFHINRIYAIVIPESVEVIGISAFRQNGAKHVMFMGDKLIS
                     IGEMAFLSNTLEEVDLSSLAGLKTIAVQAFADNHLRELKLPDSLMRIEAEAFKINRLQ
                     RVTVPDTVISISFNAFDHNSDDKVVLRTTNHNKNLLADGNGFIVDPDLLSADQSTVQA
                     VLEDLRRLDLASLRADTAAHFMTLITRGKQLLKESAVRLGYQLRFLAESRFFLGRVRL
                     DQLIKTADITLSSHQDTPNAKLLMAKLDKAKLHYNNSAMTAPKVSRLEKELSLLIDLV
                     QGVGAISKATMTQGVYKLQTTLPIPEYYIGVNLYTDDQGNILFVLDMSDTIGQGQLDD
                     YGNPILNVDEDNEGYHALAIESLADYEGLTIKDILTKELNQLPIRDVKQAREHRVGLF
                     MAIRDAAREAQLLLEKQSKALSESAGKSNGSKVADSGLEPSVTLSTNKTKLLPKTGAF
                     KEAWVTMIGMLVLLAATLLKGDSRYKKK"
     gene            complement(15031..17124)
                     /locus_tag="TVB59_000372"
     CDS             complement(15031..17124)
                     /locus_tag="TVB59_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEL1009314.1"
                     /translation="MATYYGKDPFENMDDIFNQLMGNIGGYRSENRRYLVNGREMTPE
                     EFQEYRKTGKLAAAEGQEKQASSLKKDGILTKLGTNLTEEARQGRLDPVIGRNDEIQA
                     TAEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGLEA
                     GTQYRGSFEENIQNMVKEVKEAGNIILFFDEIHQILGAGSAGSDSGSKGLADILKPAL
                     SRGELTLIGATTQDEYRNTILKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQHH
                     NVILPDSVLKAAIDYAIQYIPQRSLPDKAIDLVDMTAAHLAAQHPVTDLKSLEAEITK
                     QKELQEKAVAEEDFEKALTAKTRIEELQKQINHHSEGQKVTATVNDIAESVERLTGVP
                     VSNMGASDLERLKEISNRLKGHVIGQDGAVEAVARAIRRNRAGFDDGNRPIGSFLFVG
                     PTGVGKTELAKQLALDMFGSKDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNQNTL
                     TERVRRSPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTINFKNTVIIATSNA
                     GFGHQAGDRADQEPAIMERIAPYFRPEFLNRFNGVIEFNHLAKKDLQEIVALMLTEVN
                     QTLAKKGISLEVTDDVKERLIDLGYDHAMGVRPLRRVIEQEIRDRITDYYLDHPTAKH
                     LLASLDQDTITISEK"
     gene            17495..17914
                     /gene="ndk"
                     /locus_tag="TVB59_000373"
     CDS             17495..17914
                     /gene="ndk"
                     /locus_tag="TVB59_000373"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEL1009315.1"
                     /translation="MEQTFFMVKPDGVKRGLVGEILRRIERRGFTFDRLELRQATPEL
                     LAKHYDTLINKPFYPELEAYMTSGPVLIGIISGNRVVSSWRTMMGVTNPKDALPGTIR
                     GDFAQAPGDDGGIFNVVHGSDSRDSAKREIAIWFGHS"
     gene            18415..19221
                     /locus_tag="TVB59_000374"
     CDS             18415..19221
                     /locus_tag="TVB59_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL1009316.1"
                     /translation="MNKQSMTHFSKKLMKLALLGLALPLSLVSVVDTPVLNQSEKAVY
                     ANDFGSGNRASDYVPAANAWSFEAYPDYYSILGASHLNPAVFPEPSKMSYSPLDELGR
                     TQVARGTITYHNIVMNYNVRQRFAKNQNPSGWIGNPRNVRYTIEWLDGLSYQGDFWNR
                     SHLIADSLGGAALRVNAITGTRTQNVGGRNQRGGMRYIEQKVQQWIEQHTSAVVYYEA
                     VPIYQANELVPRAVVVSALSSDGGLDEKVMVYNTANGYTIDYATGAFRSN"
     gene            complement(19513..20478)
                     /locus_tag="TVB59_000375"
     CDS             complement(19513..20478)
                     /locus_tag="TVB59_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEL1009317.1"
                     /translation="MNNRNKRRKKRKIFKMINLMLLLACIIGLSAIVYLYKSHSKISI
                     SQLSQAIPKISLFSKTDKKPAPKPSKKATNKEASHTNSQQQKGAVSWTKQQNPVKLPI
                     LMYHAIHVMAPEEAASANLIVAPDLFESQLKAMKEAGYYFLSPEEAYRVLSANELPAE
                     KVVWLTFDDSMVDFYNVAFPILKKYDIKATNNVITGFTEAGNAANLTLDQMKEMKQAG
                     MSFQDHTVNHPDLSQASAASQTAEMKDSKEYLDRELHQDTIAIAYPAGRYTDTTLKIA
                     EDLHYKLGVTTNEGLASAANGLLSLNRIRILPTTTADILMNTISQ"
     gene            20650..21933
                     /locus_tag="TVB59_000376"
     CDS             20650..21933
                     /locus_tag="TVB59_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEL1009318.1"
                     /translation="MSVKVALLGFGTVASGIPLLLENNSSKIRAVVGDDLVIAKVLVR
                     DETTKKRLLDQGYSYQFVTSIDDIVDDESIDMVVELMGRIEPAKTFISRALSAGKPVV
                     TANKDLIALYGGELSTLAAKHQVALYYEAAVAGGIPILRALADSFASDKLTRLLGVLN
                     GTTNFMLTKMIDEGWTYERALQKAQELGYAESDPTNDVKGIDAAYKVAILSQFAFGMT
                     IDFEAISYSGIDKVRVEDVTVAQKLGYVIKLVGLLEETASGLNAEVSPVFLPKTHPLA
                     AVDGVMNAVYIESIGVGQAMFYGPGAGQMPTATAVVADMIQTACTLRDHTVSVFNRFA
                     TKTRLAKSEDIMSPYYFAIQATNKFGQLLELTRLCDVCGIRVEQLLSDEIDSDRLDFV
                     MITHEMSKKELACFTALLQDHQDFRMLSTFKILGD"
     gene            21935..22795
                     /locus_tag="TVB59_000377"
     CDS             21935..22795
                     /locus_tag="TVB59_000377"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEL1009319.1"
                     /translation="MKIRVPATSANLGPGFDSMGIAVSKYLEVDILEERDQWFIEHDL
                     GDIPNDDSNLLIQTALRLAPNIPAHRLKMTSDIPLARGLGSSSSVIVAGIELANQLGH
                     LNLTDDRKLAIATRIEGHPDNVAPAIFGQLVIASQIGKDVDYIIAPFPDLSLVCFIPD
                     YELKTSDSRDVLPKQLSYKQAVAASSVANLAIAALLTGNLKKAGRAIENDQFHEIYRQ
                     RLVREFQPIKRAAAANGAYATYLSGAGPAIMVMCPNKKKMAIYEAIEQLGLIGQLVSL
                     ELDRQGLCLV"
     gene            22960..24219
                     /locus_tag="TVB59_000378"
     CDS             22960..24219
                     /locus_tag="TVB59_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEL1009320.1"
                     /translation="MNYQETLDWIHGQERFGIKPGVKRMRWVLEQLGNPQDRIRGIHV
                     VGTNGKGSTVNDLQHIFTRAGYEVGTFTSPYIMDFKERICLNGEMISETDLVKAANCI
                     RPLTDRLISETSLGPATVFELITLIMFLYFGESHPVDIAIIEAGLGGLYDSTNVFQAM
                     AVVCPSIGLDHQAILGDTYADIAYQKAGVLKGGEDLIFAIDNKEARQVFLKKAEQLGV
                     PIWEWRRQFNMLQGEGGYQFNSQLGQLSHLVLAMPGQHQVANAGLATMTSLILQDRYP
                     KVTESVIREALASSFWLGRTELLAPNLMIDGAHNNESIAALIDVISSDYQDKQIHILF
                     GAIDTKPVSDMLQSLERLGDVQVTSFHYPNAYPLEAYPDRLTKVADFRAFLDRLEQAA
                     ADDFFLITGSLYFISEVRQYWKKVLSK"
     gene            24219..24842
                     /gene="folE"
                     /locus_tag="TVB59_000379"
     CDS             24219..24842
                     /gene="folE"
                     /locus_tag="TVB59_000379"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEL1009321.1"
                     /translation="MLSHINSSNKINQLKRGKPLPINQKKAEAAIYQLLEAIGEDPNR
                     EGLRDTPKRVAKMYLEMLSGLEQDAKDEFTAVFTEHHDDLVIVKDISFYSMCEHHLVP
                     FYGKAHIAYLPSDGRVTGLSKLARAVEVTSKRPQLQERLTAQIANALVDALQPKGVFV
                     MVEAEHMCMTMRGVKKPGSKTITTTARGIYKDSRDDRREVMQLIMEG"
     gene            24850..25650
                     /gene="folP"
                     /locus_tag="TVB59_000380"
     CDS             24850..25650
                     /gene="folP"
                     /locus_tag="TVB59_000380"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEL1009322.1"
                     /translation="MTIGHYSAAGEAAIMGILNVTPDSFSDGGSYTSVNQALAQAEKM
                     LSEGATVIDIGGESTRPGCQFVPAEEEIARVVPIIKAIKKRYDVLISIDTYKTETARA
                     ALEAGADMLNDVWAGLYDGQMLSLAAEYDVPIILMHNQTKEAYADVTKEVCSFLQARA
                     AAALKAGVKKEHIWLDPGFGFAKNVEQNIALLKGLNEVCQLGYPVLFGISRKRVVDAL
                     LGGGTKAKDRDGATAALSAYAINKGCQMVRVHNVGANRDIVSVLSQLR"
     gene            25657..26016
                     /gene="folB"
                     /locus_tag="TVB59_000381"
     CDS             25657..26016
                     /gene="folB"
                     /locus_tag="TVB59_000381"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HEL1009323.1"
                     /translation="MDKIRLEACRFYGYHGAFKEEQVLGQIFVVDLELSVDLMAASLS
                     DCLEDTVHYGLVFETVRQIVEEKTFTLIERLAGAICQELFAQFLPIKAIKIAIKKENP
                     PIAGHYQAVGIELERKR"
     gene            26013..26519
                     /gene="folK"
                     /locus_tag="TVB59_000382"
     CDS             26013..26519
                     /gene="folK"
                     /locus_tag="TVB59_000382"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEL1009324.1"
                     /translation="MTLVYLGLGTNMGDRAGYLQAAVNALSKLPETELLRQSSIYQTA
                     AWGKTDQNAFLNMACQLDTRLTSEALLAATQAIEQALGRVRHEKWGPRTIDIDLLLFG
                     DEPYQSETLVIPHPYMTQRAFVLIPLLEIAPDVTLPGSQKSLRSYLDALEQSDVALWS
                     HEYSNKFS"
     gene            26615..27502
                     /gene="murB"
                     /locus_tag="TVB59_000383"
     CDS             26615..27502
                     /gene="murB"
                     /locus_tag="TVB59_000383"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEL1009325.1"
                     /translation="MIAELEGIDIRENEALKHYTYTQVGGPADFLAFPRNHYELSRIV
                     DYANHNHIPWMVLGNASNLIVRDGGIRGFVIMFDKLNAVRLNGYTLEAEAGANLIETT
                     KVAKFHSLTGFEFACGIPGSIGGAVFMNAGAYGGEIAHIFLSAKVLTPEGKIKKISAR
                     EMAFGYRHSVIQETGDIVISAKFALKPGNHDSICQEMNRLNHLRKLKQPLEFPSCGSV
                     FKRPPGHFAGQLIMDANLKGHRVGGVEVSKKHAGFMINVADGSAKDYEDLIAHVIRTV
                     EQASGVRLEPEVRIIGESL"
     gene            27548..28702
                     /locus_tag="TVB59_000384"
     CDS             27548..28702
                     /locus_tag="TVB59_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1009326.1"
                     /translation="MTKPIITFDNVSKTFEDSGTQVLKNINFELEEGKFYTLLGASGS
                     GKSTILNIMAGLLDATSGDIYLDGERINDLPTNKRDIHTVFQNYALFPHMTVFENVAF
                     ALKLKKVDKQEIARRVKETLKMVQLEGYEKRSIQKLSGGQRQRVAIARAIINQPRLVL
                     LDEPLSALDLKLRTEMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVASFIGESNIINGTMIKDYLVSFNGKEFESVDGGMRPNEPVEV
                     VIRPEDLQITLPEEGKLQVKVDTQLFRGVHYEIIAYDDLGNEWMIHSTRKAIEGEVIG
                     LDFTPEDIHIMRLNETEEEFDARIEEYVEIDEHADGLINAIEEERNEENL"
     gene            28686..29480
                     /locus_tag="TVB59_000385"
     CDS             28686..29480
                     /locus_tag="TVB59_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1009327.1"
                     /translation="MKKTSSLFAVPYFLWIVLFVMAPVALLLYQSFFDIEGRLTLANY
                     ETFFSSWTYLRMGLNSILYAGIVTLVTFLISYPTALLLTRLKHKQLWLMLIILPTWVN
                     LLLKAYAFMGIFGQQGGINSFLTFMGLGPQQILFTDFSFIFVASYIELPFMILPIFNA
                     LDDIDDNIINASKDLGANDYQTFSRVIFPLSLNGVRAGVQSVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLTTENWGMGSTIGVVLIIAMIVIMWLTKEKSK"
     gene            29477..30253
                     /locus_tag="TVB59_000386"
     CDS             29477..30253
                     /locus_tag="TVB59_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1009328.1"
                     /translation="MKKFANLYLACVFILLYIPIFYLIVYSFNKGGDMNGFSGLTLEH
                     YKTMFDDSRLMAILLQTFVLAFTSALLATIIGTFGAIFIHQSKKKYQNAILSANNVLM
                     VSPDVMIGASFLILFTSLKFQLGILSVLMSHIAFSIPIVVLMVLPRLKEMNQDMINAA
                     YDLGANHFQMLKEVMLPYLTPGIIAGYFMAFTYSLDDFAVTFFLTGNGFTTLSVEIYS
                     RARRGISLDINALSTIVFLFSILLVIGYYYISQDKEEKHA"
     gene            30246..31319
                     /locus_tag="TVB59_000387"
     CDS             30246..31319
                     /locus_tag="TVB59_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEL1009329.1"
                     /translation="MRKLYSFLAGIIGVILLLATLSFILQKKTSSASQSDKLVIYNWG
                     DYIDPALLKKFTKETGIEVQYETFDSNEAMYTKIKQGGTTYDIAVPSDYTIDKMIKEK
                     LLVKLDKSKLVGLDNIGQEFLGKSFDPHNDYSIPYFWGTVGIVYNDQLVDKAPMHWED
                     LWRPEYQNSIMLVDGAREILGVGLTTFGYSVNSKHLKQLEAAEKKLQALTPNVKAIVA
                     DEMKGYMIQGDAAIGVTFSGEASEMLDNNDHLHYVVPSEGSNLWFDNLVLPKTMKHEN
                     EAYAFINFIMKPENAAQNAEYIGYATPNTKAKALLPDDIKNDPAFYPTDETVKKLEVY
                     DNLGSKWLGIYNDLYLQFKMYRK"
     gene            31477..33009
                     /locus_tag="TVB59_000388"
     CDS             31477..33009
                     /locus_tag="TVB59_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HEL1009330.1"
                     /translation="MENHKNEFTFSKHSIIAYVWRGILVGIIAGAIVSLFRLLIEMVS
                     EAVVGYYHQAHSNRMLLVPIAGFSLLAVFLVGLLVKSDANIKGSGIPHVEGELKGLMS
                     PNWWSVLWKKYLGGTIAISMGLMLGREGPSIQLGAMSAKGLAKYLKSSRLEKRVLIAS
                     GAAAGLSAAFNAPIAGLLFVVEEIYHHFSRLVWITALVASLVANFISLNIFGLRPVLA
                     MPKAMPFLALHQYWLLLILGLVLGCLGFLYEEVILHFHRVYDFLGKSLRLAPHFHGLI
                     VVAIILLIGYYLPQLLGGGHGLIMSLSEQKLPLLTVLAYFFIRFLGSMFSYGSGLPGG
                     IFLPILTLGALSGTIFGLILQQIGLLDRQMIPLFLVLGMAGYFAAVSKAPLTGMILVT
                     EMVGDLKPLMAIAVVTFVAYLVMDLLNGQPIYEAMLEKMAIKHPTDLVEPTLIELPVS
                     EKIAGRYVRDLKLPKNVLITTQLHHKKSQVVSGDTLLISGATIFLVVNEADTGFVREV
                     LM"
     gene            33215..33829
                     /locus_tag="TVB59_000389"
     CDS             33215..33829
                     /locus_tag="TVB59_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase"
                     /protein_id="HEL1009331.1"
                     /translation="MLEVISKELRHYQKNKLAAYQKKNQGIEAGGIVFAGDSLIEFFP
                     LKKYFKQVSTIYNRGIAGIDSQWLLEHIDSHVNDLEPSHVFILIGCNDIGLGFDQSHI
                     VSTIVDLISRIRSQSIYTRISLLSLLPVSENPAYQATVKLRTNRAIDEINQALAMIPA
                     IEFIDLNACLKDETGGLAAAYTVDGIHLNALGYEHLAQAISPYL"
     gene            34177..35304
                     /locus_tag="TVB59_000390"
     CDS             34177..35304
                     /locus_tag="TVB59_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEL1009332.1"
                     /translation="MKFEKKQVFYVVLAFVLCYAIQANWDNGANIVTTVYKTSLPFLY
                     GAAVAYIVNIVMSAYERAYTYTLKPFPFAMKARRGLCMLLAYFTFISLIVWIISIVIP
                     DLIASISSLTQFDTRAIKEVISDLGHNKLIARAINYIGGDAKLTETITNYSQQLLKQF
                     IGVLTGILTSVTAVASAIINVVISFVFSLYVLASKEELCQQATTLIDTYTGKYAKAIH
                     YLVGLLHSRFRGFFVSQTLEAMILGSLTAIGMFILQLPFAGTIGVLVAFTALIPVVGA
                     SIGAAIGFVLIMTQSMSQAVVFIVFLVILQQIEGNFIYPRVVGGSIGLPAMWVLMAIT
                     IGAALKGIVGMIVAVPLAATLYQVVKDHIHKKQALQNRQSS"
     gene            35456..36133
                     /gene="radC"
                     /locus_tag="TVB59_000391"
     CDS             35456..36133
                     /gene="radC"
                     /locus_tag="TVB59_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEL1009333.1"
                     /translation="MYSIKTDHKLMPRERLIRLGPEKLSNQEQLAILLRTGNKEKHVL
                     ELSAYLLSSLDSLADLKKFSLQELQRLSGIGKVKAIEIKAMLELADRIQIAGQAVADP
                     VLSSAQVAEKMMIELGDKQQEHLVAIYLDSQNKIIEEKTIFIGTVRKSIAEPREILYY
                     ACKNMATSLIVVHNHPSGLTKPSANDYHFTEKIKRSCDYLGLICLDHIIVSKYDYYSF
                     REKSDLF"
     gene            complement(36135..36830)
                     /locus_tag="TVB59_000392"
     CDS             complement(36135..36830)
                     /locus_tag="TVB59_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEL1009334.1"
                     /translation="MSKTIIGITANQRGTKALDNLPCSYAPTSFIEAVTRSGGLPLLL
                     PIGDEAAAKSYVAMVDKIILIGGQHVDPKYYHEKRAALDGDFSPQRDIFELAIIKEAL
                     AQKKPILGICRGMQLINVALGGSLNQHIEGHWQKTASDCLSQEIVIEKTSPLYPIYGP
                     RALINSFHHQSLKQVAEDLRVIARDPNDGTIEAVISCNPDIPFLGVQWHPELLQAIRE
                     EDLRLFDWFIHSF"
     gene            complement(36842..37486)
                     /locus_tag="TVB59_000393"
     CDS             complement(36842..37486)
                     /locus_tag="TVB59_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEL1009335.1"
                     /translation="MVIDKSIPKATAKRLSLYYRIFKRFYADQVEKASSKQIADAMGI
                     DSATVRRDFSYFGELGRRGFGYDVTKLMNFFADLLNDHSTTHVILVGCGNIGRALLHY
                     RFHDRNKMQIVMGFDTDDNPMVGTKTPDDIPIYGISTIKEHLDNSGIETAILTVPSIY
                     AQEVADQLIEAGIRGILSFAPLHLQVPKGVIVQSVDLTSELQTLLYFMNQNHLD"
     gene            complement(37772..38119)
                     /locus_tag="TVB59_000394"
     CDS             complement(37772..38119)
                     /locus_tag="TVB59_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEL1009336.1"
                     /translation="MAFEKEIALKDCKYSYRISPKIKKYTLRDTTFSQTKIGHYQLTR
                     LLEKVPNSGEGFPLKITINKDLDGFKLAITDQSGLRLVNIFKSEEHSILQDKFYFLMD
                     SLVERDIFIKKEC"
     gene            complement(38109..39236)
                     /locus_tag="TVB59_000395"
     CDS             complement(38109..39236)
                     /locus_tag="TVB59_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEL1009337.1"
                     /translation="MIYFDNAATTSLSQAAIKAMTEAMADDFGNPSSIHAYGRQANKQ
                     LRECRKAIANCLGAAENHIIFTSGGTESNNTAIKGYALAHQEKGKHLITTAIEHHSVL
                     STMAYLEERFGFEVTYLEAKNGIIDLNQLQAALREDTILVSMMFANNETGDLLPIQAV
                     GSMLKQHQAVFHVDAVQAIGKVPIQPADLGIDLLSASAHKFHGPKGTGFLYNKGLKLA
                     PLLHGGNQENKQRAGTESLINIVGMTQALDEAVSRLPQHYQHAKELSQLLLSELEGIS
                     YQLNHNECHLPYIINIGFPGYQNHVLLTQLDLAGFAVSSGSACTAGAVEPSHVLAAYF
                     GKQSHRLTEAIRVSFSEQNTQKDVIALATQLKNILGGSYGI"
     gene            complement(39239..40213)
                     /locus_tag="TVB59_000396"
     CDS             complement(39239..40213)
                     /locus_tag="TVB59_000396"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEL1009338.1"
                     /translation="MTERYADKQIKLFSLTSNLAIAEKISKAAGIPLGKVSSRQFSDG
                     EIMINIEETVRGDDIYIIQSTSFPVNDNLWELLIMIDACKRASANTVNIVLPYFGYSR
                     QDRVAKSREPITAKLVANMLTKAGIDRVVTLDLHAVQVQGFFDIPVDNLFTVPLFAKH
                     YYPLGLSGPDTVIVSPKNSGIKRARSLAEYLNSPIAIIDYAQDDAEREEGYVIGDVAG
                     KKAILIDDILNTGKTFAEAAKILECAGATDIYAVASHGIFAGGAADILETAPIKEIIV
                     TDSVKTKNRIPKTVTYLSASDLIAEAIIRIHERKPLSPLFSYKPESTN"
     gene            complement(40348..40920)
                     /locus_tag="TVB59_000397"
     CDS             complement(40348..40920)
                     /locus_tag="TVB59_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEL1009339.1"
                     /translation="MTNLEIEYKTLLTKDEYNRLLSQMTHVPPVTQTNYYIDTDHFDL
                     KAHKMSLRIRTFVAAPAELTLKVPEKVGNREYNLELDDTQAKAIIQTGQLPKSAILDI
                     ISTLDVDLSAIKTFGNLTTIRREADTPIGKLALDYNQYAGIKDYELELEVTDPVRGKV
                     DFDHFLAQHQITFKYSKSKVARFSKTLKKS"
     gene            41015..41686
                     /locus_tag="TVB59_000398"
     CDS             41015..41686
                     /locus_tag="TVB59_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEL1009340.1"
                     /translation="MALDWEEFLDPYIQTVGELKIKLRGIRKQFRKQNRYSPIEFVTG
                     RVKSVESIKEKMALRGVLEENIAQDIQDIAGLRIMVQFVDDIEDVLSLLRQRQDMTIV
                     YERDYIRNMKSSGYRSYHVVVEYPVDTIEGQKKVLAEIQIRTLAMNFWATIEHSLNYK
                     YGGDFPEEIKKRLEVTAKIALELDEEMRKIREDIREAQLLFDPVTRHLSDGVGNSDDT
                     DELYR"
     gene            41661..42497
                     /locus_tag="TVB59_000399"
     CDS             41661..42497
                     /locus_tag="TVB59_000399"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEL1009341.1"
                     /translation="MTQMNYTDKVKRVAIIANGKYQSKRLASKLFGVFKDDPSFYLSK
                     KNPDIVISIGGDGMLLSAFHMYEKELDRVRFVGIHTGHLGFYTDYRDFEVDQLIANLR
                     RDTGEQISYPILKVVITLDDGRLFKARALNEATIKRIEKTMVADIIINNVKFESFRGD
                     GISVSTPTGSTAYNKSLGGAVLHPTIEALQLTEISSLNNRVFRTLGSSVIIPKKDKIE
                     LVPKRLGVYTVSVDNKTYHLKNVVKVEYFIGNEKIHFVSSPSHTSFWERVKDAFIGDS
                     ES"
     gene            42494..43396
                     /locus_tag="TVB59_000400"
     CDS             42494..43396
                     /locus_tag="TVB59_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEL1009342.1"
                     /translation="MRFEFVATKKTKVKTLLKEHDVSKGLLAKIKYKGGNIWVNGVAQ
                     NAIYLLDIGDVVAIDIPNEESFEQLTAISHDLDIVYEDEHFLILNKPAGYASIPSAIH
                     SNTIANFIKAYYIKQDYPNKQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQQRAIN
                     KRYYALVCGQERLPDQGEIIAPIGRTDDSIITRTVTPKGKYAKTSYKVIARYPENVSL
                     VDITLHTGRTHQIRVHFAHLGFPLLGDDLYGGRLDLGMTRQALHCHHLSFTHPFTESR
                     SDHTICLTDDFESVIIDLQKKDRG"
     gene            43400..44401
                     /gene="pta"
                     /locus_tag="TVB59_000401"
     CDS             43400..44401
                     /gene="pta"
                     /locus_tag="TVB59_000401"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEL1009343.1"
                     /translation="MSIRNLFGGLREKIVGKNMKIVFPEGNDERVVRAAARLKFEGLV
                     EPIILGQADDIRSLLTQLGFAEQHYTIINPNDYADFEKMKAAFVELRKVKATLEDADR
                     LLRDVNYFGVMLVKLGLADGMVSGAIHSTADTVRPALQIIKTKPGISRTSGVFLMNRE
                     NTEQRLVFADCAINIDPTAQELAEIAVNTADTAKIFDIDPKVAMLSFSTMGSAKAPQV
                     EKVQEAVRIAKELRPELALDGELQFDAAFVPSTAAIKAPDSSVAGHANVFVFPDLQSG
                     NIGYKIAQRLGMFDAIGPILQGLNKPVNDLSRGSSAEDIYKLAIITAAQALENESIN"
     gene            44501..45259
                     /locus_tag="TVB59_000402"
     CDS             44501..45259
                     /locus_tag="TVB59_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HEL1009344.1"
                     /translation="MTKIALVTGASAGFGKAIAEQLIAQNIKVIGAARRIEKLRELEG
                     IFGSERFYPLQMDVSEPTAIDKALAELPKEWQAIDILVNNAGLALGLDKAYEADVANW
                     LTMINTNIIGLIYLTRQVLPQMVSSNNGMIINIGSTAGTIPYPGANVYGASKAFVKQF
                     SLNLRADLAGTNIRVTNIEPGLCEGTEFSHVRFKGDHERVKALYAGAHAIQPRDIANT
                     VSWIIDQPEHVNINRVEMMPVSQSYGSQPVSRHD"
     gene            complement(45364..46050)
                     /locus_tag="TVB59_000403"
     CDS             complement(45364..46050)
                     /locus_tag="TVB59_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter"
                     /protein_id="HEL1009345.1"
                     /translation="MTKTIYTLALVDDKNNLQKTFFTTLSQEFSYLFHITIVRQLTTE
                     QLKKAQAIFTFQNLEASLPVLYFNQADKEQGFTVSDHTFTDSQQTLRLAKYLMQFYQA
                     LAPHFLTYLPLQARIADHQGQIIFDNHRFNGNFFASDKHDVIEDWILTDLHKAATGSK
                     LYLIPTASQDHIYMQQYQALYDDTKQFVGVYDMILDFKPMLQHYLEETGQAIVGWSDV
                     TSGPSLSDHF"
     gene            46305..47033
                     /locus_tag="TVB59_000404"
                     /pseudo
     CDS             46305..47033
                     /locus_tag="TVB59_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922297.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            47026..48558
                     /locus_tag="TVB59_000405"
                     /pseudo
     CDS             47026..48558
                     /locus_tag="TVB59_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_028398951.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
     gene            48916..49899
                     /gene="guaC"
                     /locus_tag="TVB59_000406"
     CDS             48916..49899
                     /gene="guaC"
                     /locus_tag="TVB59_000406"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007891361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEL1009346.1"
                     /translation="MFNDMPVFDYEDIQLIPNKCIINSRSEADTSVRLGNYTFKLPVI
                     PANMQTIIDETIAEQLARDGYFYIMHRFDEEGRKPFIQRMHEQQLIASISVGVKDYEY
                     DFVSSLKEDAPEFITIDIAHGHADSVIKMIKHIKAELPETFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAAVRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGATMVMIGSLFAGHIESPGKMVEIDGQSFKEYYGSASEYQKGEHKNVEGKKIL
                     LPTKGHLADTLTEMKQDLQSSISYAGGRDLESLRRVNYVIVKNSIWNGDSI"
     gene            50085..50666
                     /locus_tag="TVB59_000407"
     CDS             50085..50666
                     /locus_tag="TVB59_000407"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEL1009347.1"
                     /translation="MRLLEERILADGTVLGETILKVDQFLTHQVDYRLMKEIGRVFAD
                     QYADLGITKVVTIEASGIAPAVYTAEALEVPMIFAKKHKNITMTEGILTAEVYSFTKQ
                     VTSTVSIAGGLLSKEDRVLIIDDFLANGQAAKGLIDIIHQAGAKAVGIGIVIEKSFQA
                     GRQLLEDLGVEVTSLARIKHFDNGIVSFLEADA"
     gene            complement(50954..>51519)
                     /locus_tag="TVB59_000408"
     CDS             complement(50954..>51519)
                     /locus_tag="TVB59_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEL1009348.1"
                     /translation="DQSLGSIFLKEKGMSIDLGALAKGYIADKLMAFLIKDGITAALI
                     NLGGNVLVHGTNKQRHNGLFYVGIQQTNQKRGQHVGVIKVNNKSVVTSGIGERQLQIK
                     DKTYHHLLDPHNGYPIKTNMASLTIVSQFSLDGELWSSRLFGLEHSFVLSQLNKLPEV
                     EGIIITKDGQVTISDGLKGAFRLHYKH"
BASE COUNT        14553 a         9754 c        11811 g        15401 t
ORIGIN      
        1 ttaataactt agatgaagat aatttgttga aaatatatgt agataatata attgataaaa
       61 taattgcatc aagaactgga gaaatagaga ttatagagaa atagataatt caggaaattc
      121 tatatcaatt gcttgacatt gtagggaaag tcctctatca tgaatttgct gtatcgcttt
      181 tatgatgtac aatcaggcct cattacagtt gatgggcaaa atattcagga gtattctaga
      241 gaaagcctgc gttcacagat gggtattgtc ttgcaggatc cttatttgtt tacaggaacg
      301 attgcttcta atatcacgat gggaaatcca gcttattcgg atcaggatat tttagatgct
      361 ttggaaaagg tcggagcctc ttcgatgatt gctcgtctgg aaaagggcat tcatgagcct
      421 gtctatgaaa aaggctcctc ttattcaagt ggcgagcggc agctaattgc ttttgctagg
      481 acattgattg ccgaccctaa aattttgatc ttagatgaag cgacctcgca cattgatact
      541 gagacagagg acatcattca acaggctatg gaggtcttaa agaaaggccg aacaaccttt
      601 atcattgccc atcgcttgtc taccattcaa tctgctaatc aaattttagt attggataag
      661 gggaggatcg tcgaaagagg aacacatcag gaattgctag atcagcaagg catttatgct
      721 gaaatgtcca agctacaaga aaaggtggct gtacagtaat gctttttagt gatagctatc
      781 aaaaaattcc ttttctaggc cgtgttaagc agcagtagtc tgtgaagtag gagctatatt
      841 taggttttgt gcctaagcct ttaaggtttt taagaggctg gattagggct taacatcaat
      901 aaaatcatat gtcactttat cacagcatgt tgtggtgaag tgttttttgt gtcgtcctgc
      961 taaagggaag atcctcacag tcagggcttg gctggctcct ttatcagagt cagatcattc
     1021 atacgtactt cctgtcaggc ttggctaagt tgaattgtat gttgagatca gcatgtcagc
     1081 aatttatgct ttgtgtctga cttttagcag cttgtacatg aaataggact aaaggacact
     1141 tgaattgatg aagaatcagc ttaaaaacca tttgtcctag ataggataag aactgtctaa
     1201 aagggggata gatcatcgca atttttaaca atttagtgta aaatagtaag gtgaatgttt
     1261 tgatgaaata aacgaaaaga tttaggatat gaataagaca attggatatg gcaaggcaca
     1321 cagcaaaatc attttaatgg gtgagcattc tgtggtctat ggctaccctg cgttggcctt
     1381 gcccttaaaa gatattgaag tgacctgccg gattttccct gctgcaaagc ccttagcctt
     1441 tgatttttat gatcccttat caacggcagt ttatgcagcc ttggagcatt tggggtgctt
     1501 ggcagagccc attcattatg atattatgtc tcaggtacca caaaagcggg gcatgggctc
     1561 ctcagcagct gtttcgattg cagctgttcg agctgttttt tcttattttg ggcagccctt
     1621 gtcagatgag ctgttggaaa tcttggtgaa taaggcagaa atcattgctc acaccaatcc
     1681 cagtggccta gatgctaaga cctgcctcag tgataaggcc atcaaattta ttagaaatgt
     1741 tggttttgat accattgata ttcagttaaa tgcttatttg gtcattgctg atacagggat
     1801 tcaggggcat acgcgtgagg ctgtcaataa ggtggctcaa tttgaggagg aaaatcttcc
     1861 tcatttagcc aagcttggct gtttcacaga ggctgttgag caagcaatta agacaaacga
     1921 ttgcctagct attggacgat tcatgacgca ggcacatgaa tcactaaagg ctattggtgt
     1981 cagtgtggca aaggctgatc agctggttgc agcagctctt gaggctggcg ctttaggagc
     2041 taaaatgact ggtggtggct taggaggatg tatgattgca ttagctgaaa ggataacaga
     2101 cgctcagcaa atcagtaaga aactaaaaga agagggagct gtaaatacgt ggattcaaat
     2161 actgtaacgg taacttccta cgctaatatt gctattgtca aatactgggg gaaaaaagat
     2221 gaggctaaga tgatcccatc aacctctagt atttctttga ccttggaagg catgtacacg
     2281 acaacaagtc tttctttttt gcctgcctca gcaaagggag atcagtttta tatcaatggt
     2341 gttctgcagg acgccaagga gcatgctaag attactgcga ttttggatca gttccgtcag
     2401 aaggaccaga cttttgtcaa ggttgaagcc agcaacagca tgccaactgc ggcaggctta
     2461 tcctcaagct ctagtggctt atctgctctg gtaaaggcct gcaatcagct ttttcaagct
     2521 aagctaagtc aagaagagct tgcccaaaag gctaagtttg cctctggctc tgcttcgcgt
     2581 tctttttttg gccctgttgc tgcctgggat aaggatacag gctctattta taaggtcaaa
     2641 acagatttaa agctggccat gattatgctg gtcttgaacg atgctagaaa gcccatttcg
     2701 agtcgagagg ggatgaagcg ctgcagcaca acctcaacaa gctttgacca gtggctggcc
     2761 cagtcagaaa gtgattatca ggccatgttg cgtgccctta gtgacaatga ttttgaaacg
     2821 gttggttggc tgacagaagc aaatgctcta gccatgcacg caacgaccaa aacagccagt
     2881 ccttccttct cttacctaac agaggcctcc tatcaggcca tgctaagggt caaagagctt
     2941 cgtcaagagg gctattcttg ctattttacg atggacgctg gtccaaatgt caaggtgctt
     3001 tgtttagaag aggacttaga gcggctgtcg cacctttttg aaagggagta tcgtatcatc
     3061 gcctcaaaaa caaaggaatt accagatgtc taaatatcat gttcaagcag gaggaaagct
     3121 gtatctgaca ggcgaatatg cgattctaag gccggggcaa acggcgttga tttgctatat
     3181 tcccataatg ctgacagctg tcattgaagc agcagaggct gttagtatca gctcagatat
     3241 gtttgaccat gctgctgatt tgtcaccgga taaggattat aggctgattc aagcctctat
     3301 tgaagccttt agtttatata tagataagga tattaaggag ctgccagcct tttctttgtc
     3361 tattactggt aagcttgagc gtgacggtaa aaagtttggg attggctcta gcggtagtgt
     3421 tgttgtacta acgctaagag ctttggcagc cttttatcag gttcagctgc taccagagca
     3481 gctctttaag ctggctgctt ataccctgct taaatcagga gataatggct ccatggggga
     3541 cattgcctgc attgcctatg agagcttggt tgcttataca tcctttgata ggcgtaaggt
     3601 tggtcaatgg ttgatcgaga tgaccctaaa agagctaatg gcagcacatt gggggtatac
     3661 gattgagact attgagcctg ctctgccctg ttggtttctt gttggctgga cccaagtccc
     3721 ttctatctca agagagatga ttcagctggt taacaagagc attagctgtc agtttttaga
     3781 gcaaagccag ctggtcacac aggaagtgat gactgccctg cagcttggtc aaagaaaaag
     3841 gctcaaagct agcattgaaa aagcgggtca gttgctgcaa gggttggctt cagttattta
     3901 tcaccctaag cttacgcagc ttgtccaggc ttgtcaaggg cttgatgctg ctgccaaatc
     3961 atcaggctca ggaggtgggg attgtggtat tgcactcgtt tttgaggcta aggacattga
     4021 gcctatcctt gccagatggc agcaagcagg gattgtatta ctatatcagg aggaatgggg
     4081 ataaacatga ctaatcgtaa ggatgaccat atcacacatg ctttgagcta tcattctcct
     4141 tacaatgcat ttgacgacat ggagctcatt cactgttcct tgccgagcta tgatttagct
     4201 gatattgatc tctcaaccca ttttgctggc tgtgattttg agtttccttt ttatatcaat
     4261 gcgatgacag gtggtagcaa gaaaggccaa gcagtcaatg aaaagctggc caaagtggct
     4321 gcggctacag gtattttaat ggtgacaggc tcttacagtg cagccttgaa aaatcctgag
     4381 gacacttcct ttcaattgcg aggtgtagca ccagatttac agttggccac caacattggt
     4441 cttgataagg ctgttgacct agggattaga gctgtcgagg aaatgaagcc cttgttttta
     4501 caggtacatg tgaatgccat gcaggagctg ttaatgccag agggagagcg cagctttaag
     4561 cattggaagg atcatttagc ggcctatgcc aagcagcttc cagtcccttt gattttaaaa
     4621 gaggttggct ttggtatgga tattaagacc atcactatag cacgtgatat gggagtaaaa
     4681 acctttgata tttcaggaag aggaggaacc tcctttgcct acatcgaaaa tcaaagagga
     4741 agtaatcgct cttacctaga cgattgggga cagacaacag tgcaatgtct attaaacgcc
     4801 aaaggtctgg ttgatgaagt ggagatctta gcctcaggtg gtgtcagaca ccccttagat
     4861 atggttaaat gcttggtgct gggggcacgt gctgtgggcc tatcgcgagt ggtattggag
     4921 ttagttgaga cctatccagt tgagcagatc atcgctacga tcaatagctg gaagaaggag
     4981 cttaagctca tcatgtgtgc tttagattgt cgaaccttga gcgatttgcg tcaggtggat
     5041 tatttattat atggtaggct ttatcaggca aaccgctaaa gactttttag ccctgagcta
     5101 actttcctta gaaaatcatc acaggagtta agaagctgcc tgcttggtgc tgcaagctaa
     5161 ttcagctgat tatggctcgt aagattttta gatgtctgaa tgaaatgata ggacagatga
     5221 catagtatag cgctaatttc tagtgaaaat cagtccttgg tcaggttact gagactgagg
     5281 ttaagtttat gtttacacta acacttaaag gatatgaaaa cacttggtag ctgccactga
     5341 agctgttacc aagtgttttt agtctatgat tggcttaatc gtatggctgt taagagctgt
     5401 cctgcctttt ctaggttcat tggcttatcc tttagtagag ccttaactag ttgaggcacc
     5461 tcctgctcac tagcacctgc taatagagct agagacttgg cctgcagctt catgtgacca
     5521 gcctggatac cagttgaggt caaagccttt agagccgcaa aattttgcgc cagcccaact
     5581 gcagtggtga tttgggcgag aaccttagca tttggttgct ctaaaaggct atgagcaaca
     5641 ctgacggttg ggttgagacc gatcgaccct cctttactag caatgggcat tggcagtgtt
     5701 agctctccgc ataagctatt tttagataaa tcaacgtgcc agctacttag ccctctataa
     5761 gagccagtcc ttgcggcata ggcatgtgct ccagcctcaa tagctctcca gtcatttccg
     5821 gtagctatag ctaccgcatc gattccatta aagattccct tattatgcgt tgctgctcgg
     5881 taagggtcaa tctgggctaa tttgcttgcc agctctattt ttttggccaa ttgctgagct
     5941 tcttccttat gtcgacttag gtatctgagg tcaacctgac atttagcact aactaaagct
     6001 tttgttgcat agtttgagag gatagccatt aagcattgac caccgcttag ggcctccaaa
     6061 tcaggtacta aagcctccat catcgtgtta acgatgttgg ctcccatagc ctcttgggta
     6121 tcaacgctca gatagacaat gaaaaaatcc tccttacgct caacggtaag gctctttgcg
     6181 ccaccaccac gcttaacaat agaagggtag gcattgtttg caacgtcaat caatgtatct
     6241 gcgttagcta gaatagccag cctagcctgc tcgtcatctt taacatcata aagagctacc
     6301 tgcccaagca tttgacgact gagtacctca gtctgaaagc cacctgatcg cttgatgatt
     6361 ttggcagcaa aggaagcagc agcaacaaca gaaggctctt cagtcacaaa ggggacctga
     6421 taggtatgcc cattgatcag aaaatcaggg gctagactaa aaggcagagc cagtcgaccg
     6481 atgacatttt cggtcatttg attggcaata gcaatgggta agagctggtc tgtctctaac
     6541 agcttttgct gctgcgggcc aagcagctgg tcatctgcga gctgttgaat gcgttctgca
     6601 aggctttttt tataaaagcc ggcccaattt ggtttagttt ttgtcatcat cttgataaat
     6661 tcgttggtgt tccttaattt ctttgagggc aaacctgcca gttagatatg gtgaaaagct
     6721 ggcattgcca tcttggtcta gtctaggctc ttcataaaaa agtgcttcat aatcagccac
     6781 tgaaatcacc tgacgttggt ctaatagggc ttgtcgatta gtcagtagca tgtccttgta
     6841 accgtcaaca agctgccctg aaaacagctc actaacagct cctgagccat agctaaacaa
     6901 tccaatccta tcaccagccc ttagcacctg actattctct aaaagtgata ataagccgag
     6961 gtagagtgag cctgtgtaaa tgttgccgat ttgcttgctg taggcaatag aagcttgaaa
     7021 gttttcataa agcctttctt tgtgatcatc tgctagtgat tttgtcatga tcttatgaag
     7081 tccctttaga gcaagctttg gaaaggggat atgaaaacaa acagcagcaa ggtctgatag
     7141 ctcaatacct tctttttctt ggtatttgtc ccaggttgtt tttagggaat caaggtattg
     7201 cttggtcgaa taaataccat tgacaaatgg tgttgagctg taatttggac gccaaaaatc
     7261 catcacatca cgtgtctgtg cgacattgtc atgatttaac tggagaatac gaggattagt
     7321 agtaactagc atagcaatac ttccagcacc ttgtgttggc tctccggcgg atccaatgcc
     7381 gtatttggcg atgtcactgg caatgaccaa gaccttggag gctgggtgtg cagcaacatg
     7441 taatttggca taatctaaag cagcagtagc gctgtagcag gcttccttta tctcaaagga
     7501 gcgtgcaaag ggctgaatat caagcagctg atgaacgtaa atactggctg cctttgattg
     7561 atcaatgctt gattcggttg ctaaaatgac catgtcaatg cttgctttat cgtctttggt
     7621 aaggatttgg tcagcagctg atgcagcaag cgttacaata tcctctgtaa caggtgcaat
     7681 gcttagagcg tcaagcatta gcccctgatg aaattttgct ggatcagtgc tgcgagcaag
     7741 tgccaggtct tccattttta agacgtattg actggtcgca aagccaatct tatcaattcc
     7801 gatgttcata aatatccttc ttttatccat tttatagtcc tatccatttt atcatatttt
     7861 cttagaaaat tagctgattt aatacgatag ttttaccttt caaaccaaaa acagcagcat
     7921 atagctttct tctggtattt ttgaaggaaa ttagataaaa taatatggac tgtgcttaca
     7981 gaaaggggtt tccatgacaa aagcagatca tatttttaaa gctaatatca aaaaaattat
     8041 ggaggaggga gtctttagcg agcaggctcg cccaaggtac aaaaatggtc aaacagccaa
     8101 ttccaaatac attacaggtg cttttgcaga gtatgatttg tctaagggag agtttcctat
     8161 tacaactcta agatcaatcc ctatcaagtc agctattaaa gagttatttt ggatttatca
     8221 ggaccaatca aacagccttg atgttttaga aaacaaatac aacgttcact attggaatga
     8281 gtgggaggtc ggtcagacaa gaaccatcgg tcagcgctac ggtgcaatcg ttaaaaagca
     8341 tgatatcatc tcaaaaatcc tcaagcagct agaggacaac ccttggaatc gccgaaatgt
     8401 gatttctctg tgggattacg aagcctttga agaatcagaa ggactgctac catgtgcctt
     8461 tcaggtgatg tttgatgtta ggcgagtaga tggtgagctg tatttagatg ccacgctgac
     8521 ccagcgctca aatgatatgc tagtggctca tcatatcaat gccatgcaat atgttgccct
     8581 gcagctaatg attgccaagc attttggctg gaaggctggt aagttctttt attttgtcaa
     8641 taatttgcac atctatgaca accaatttgc gcaagccaag gagctattgg agcgtcagcc
     8701 agcagcctgt cagcccaagc ttttgctgca tgttcctgat gggacagact tttttgatat
     8761 aagaccagag gattttgagc tacaggatta ttacccagtg aagcctcagc tcacctttga
     8821 cttggcgatt taagcgaaaa agacgatttt ttctgagcat tttgccaaga aatttgatag
     8881 aataaaagaa gttcatattg aggaaagcta gtgatgacaa agaagattat tgctatttgg
     8941 gcagaggatg aagcaggact tatcggagcg tgtggcaggc ttccttggta cctaccaaaa
     9001 gagttgcagc atttcaagga aacaacattg aatcaagcta tcctgatggg acgagtaacc
     9061 tttgagggca tgaagggtcg tttgctgcca aatcgccaaa cgcttgttat gaccagagac
     9121 agttattatc atgtggaggg cgctttaacc ataaccagtg tgcaggaggc tttggattgg
     9181 tatcatgcgc aggataagac cttatatgtg attggtggca gcaaggtttt agaggccttt
     9241 gatggttatt ttgatgtcat catcaaaaca gtggtacatc accagtttga gggtgatacc
     9301 taccgaccta ggttagagct gagtgatttt gtagaggaga cctctgtatt gtacccaagg
     9361 gacgataaca atccttacga tttcactgtt acagtattga gacatcgcta atatagggag
     9421 atgatagtct atgcagcgta gtatttttgg ggtatttacg gcctttttgt gtgcgatttg
     9481 tgttttatgt gccataccgg cctttagaaa aaatcgctat ggcttaggat tacttttttt
     9541 attaaatgcc tttactaacc tagtgaatac catacatgcc ttttatggaa cactgtttta
     9601 agcctaagag aatgaaaaga gaaagataga ggaatcatgg caggaaatcg tagtaacgat
     9661 attaaggttc attgctcgtt ttgcggcaag agccaagacg aagtgaaaaa aattattgca
     9721 ggtaataacg tctttatttg taacgaatgt gttgccttat cacaagaaat catcaaggaa
     9781 gaattggcag aagaggttct cgctgatctg actgaggtac caaagccaaa agagctgctt
     9841 gagattttaa atcaatacgt cattgggcag gagcgtgcta agagagcctt atcagttgca
     9901 gtttacaacc actacaagag gatttcattt actgagagtc gtgatgatga tgatgtggat
     9961 ttgcagaagt ccaatattct gatgattgga ccaacaggct caggaaagac ctttttggca
    10021 cagaccctgg ctaagagtct gaatgttccg tttgctattg ctgatgcaac ctctttgact
    10081 gaggcaggct atgtcggaga agatgtggaa aatatcctcc tgaaattaat tcaagccgct
    10141 gattacaatg ttgagcgtgc agagcgcggc attatttatg ttgacgaaat tgataaaatc
    10201 gctaaaaaag gtgagaatgt ctctatcact cgtgacgtat caggagaagg tgtccaacaa
    10261 gccttgctaa aaatcattga aggaacggtt gctagtgttc caccgcaagg tggtcgtaag
    10321 cacccaaacc aagagatggt acagattgat accaaaaata tcttgtttat cgtcggaggc
    10381 gcctttgatg gtatcgaaga aattgtcaag cagcgcttgg gagaaaagat cattggcttt
    10441 gggcaaaata gtcgaaagat tgatgacaat gcttcctata tgcaggagat cattgctgag
    10501 gatattcaaa aatttggtct gattcccgaa tttattggac gcttgcctgt tgtggcagcg
    10561 cttgagcagc ttaatactga ggatttgatt cgtattttaa cagagcctag aaatgccctt
    10621 gtgaagcaat atcaagcctt attgtcatat gatggcgtag agcttgagtt tgaaaagggg
    10681 gctctggagg ctattgcagg tagggctatt gagcgcaaga ctggtgcgcg tggtctgagg
    10741 tctattattg aagaaaccat gctggatatc atgtttgagg tgccaagcca agaggaagta
    10801 atcaaggtac gcattactaa ggaagctgtc gaaggtcaat caaagcctat tttagagata
    10861 gcctaaggag gtatgatgtc tgaagagcaa atccttaaca cgcataatgc ttcgatattg
    10921 cttagtgcgg caaataagtc tcattaccca caagacgacc ttcctgagat tgctttggca
    10981 ggtcggtcaa atgttggaaa atcaagcttt atcaatacta tactaggacg taaaagcctt
    11041 gctagaacct caagcaaacc tggtaaaact cagcttctta atttttttaa cgttgatgat
    11101 aagctaaggc ttgttgacgt tcctggctat ggttatgcta aggtatctaa ggcagagcgg
    11161 gctagatggg gaaagatgat cgaagagtac ctgaccacac gacaaaatct cagagcagtt
    11221 gttagtctgg ttgattttcg ccatgagtca tcacaggacg acattcagat gtatgagttt
    11281 ttgaagtatt atgagattcc ggtgattatt gtggctacaa aggcagacaa ggttcctcgt
    11341 ggtcgctgga ataagcatga gtctatggtt aaaaagtcct taaactttga tcaaacagat
    11401 gcgtttatta ttttttcatc tgttgagcgt atcggtattg atgagtcttg ggataccatt
    11461 ttagagtatt tataagcata tggtaaaaaa tttaagtatc ttttagacag gcacttgtgt
    11521 ctggtctgag aggtgctttt ttattgacaa aaaaacaatt tgttgatgac gagcttgtgt
    11581 tcaaaaatgt cagtttgcta aaaaatgatg ataacaaaca agacttttat gatataatgc
    11641 ttagcaggat aatatggaga catgagaaaa aggtcagaga cagctaattt gctatccctg
    11701 attataacta tgatgaccag cattattata atactcatgg tgctagctat tagtagcagc
    11761 acctaaccta tagtgttgct ttttaggtta caagcactgg cgctaggagt attataatat
    11821 atttagaaag gtttttttat gacaataaaa aaatgccctc aaatacttgc cttattcctt
    11881 gcttttgcag cgctagctag tcaggggcaa accgtccatg ctctggagcg gcaggagaca
    11941 tctgtcaagc aagctcatga atcagatgat tggtttgatg aggacgaagg agttagcgat
    12001 atcaagtcta atacccctac agagatagac tcaacagtaa cagagttatt tggtgatgct
    12061 gagcctaaga ctaaggctga aaaagaagag tcaaaagctc caagccctaa gcaagaagca
    12121 ctgccagcag agtctcaaaa agaaaaagag acatctgcta aatcgactga ccatgcgaca
    12181 gtacaagcag aagaggcaca gcctgagcaa ggctcagata gtccttggct agcagatgac
    12241 tttgttacta agggagatac cttggttggg ctatctaagg caggtcttgc taagttatca
    12301 aagacacctg tcttggtact accaaggata gggattgaca agacagtgtt gacaaggatt
    12361 gctagctttg cctttactcc aaataaatca gtcgctattg ctgattatac aggtagagca
    12421 ggtgaacatg gcgagatcaa tcatctggac gtcgaaggca gagatatcct tactgaggga
    12481 gaggattttg gtgcctatgc gattaaaaag cttgtgattc ctgaaggcta tctttttatc
    12541 ggtcaagatg cctttaatga caataaacag ctagaagaaa tcagtctacc tgatagctta
    12601 ctcagtattt cagactatgc ctttgctcac atgagtttat ctaagcttaa gctgccaaaa
    12661 agcctacagt ccattggaga tcaagccttt tttgataatc ggattgcagg cactttggta
    12721 ttgccaaaag ctctaaagca gctgggagaa cgcgtcttta agtccaatcg cctcactgga
    12781 cttgtctttg agggagaagg cttgtctgtc ctaaaagaag cagcctttca agacaatgct
    12841 ttcattagtc ttgttatccc agatagcatt caagccttag aagaggacgt ctttacagga
    12901 aaccttggcg atgaagaata cggtaatcat gccgttttac gaaccaaaaa tggtcagaat
    12961 ccttacagac ttcacagtgc caatgttctt gtcaatccaa gtgatcaggc tagaacacca
    13021 cagccaccaa ttgattacaa caggtggctt gcagaagatt ttacctatac tggacagacg
    13081 ataaccggtt tttcagctag tggactgcgc aaggtcaaac gcaataagca tttggttctg
    13141 cctaagaatt atcagggtca gcccttgaca gccattgcag ataatgcctt tagaaatgtc
    13201 aattttcatg ataaaacctt gcgtaaatac gacctagaaa gcgtgacgtt accatctacc
    13261 attcaaaaga ttggtgcctt tgcctttcag tcaaataatc tagaaagctt tgaggccagc
    13321 gaggacttgg ttgagattgg tcaaggagcc tttatgaata atcgcattga gattctggcc
    13381 ttgaatgata agctgaaggt cattggagat gcggcctttc atatcaatcg gatttatgct
    13441 attgttatcc ctgagtcggt cgaagtaatt ggcatttctg cctttaggca aaatggtgct
    13501 aaacatgtga tgtttatggg agataagcta ataagtattg gagaaatggc ttttttgagc
    13561 aatactctgg aggaagtgga tttgagcagc ttagcagggc ttaagaccat cgctgttcaa
    13621 gcctttgcag acaatcactt gagagagctt aagctgccag atagtttgat gcgtattgaa
    13681 gcagaagctt ttaaaattaa tagacttcaa agagtgaccg ttccagacac tgtcattagc
    13741 attagcttta atgcctttga tcataatagt gatgacaagg ttgtcctaag gaccaccaat
    13801 cacaataaaa acctgctagc tgatggaaat ggctttattg tggatccaga cctattaagt
    13861 gcggatcaat cgactgttca agcagtttta gaggacctgc ggcgcttaga tctagctagt
    13921 ctacgtgctg atacagcagc tcattttatg acactcatca caagaggtaa gcagctacta
    13981 aaagaatccg ctgtacggtt aggttatcag cttaggttcc ttgcagagtc acgatttttc
    14041 ttagggcgcg tgagactgga tcagctgatt aaaactgctg acataaccct atctagccat
    14101 caagacacac ctaatgctaa gctgttgatg gctaagctag acaaggccaa gctgcattac
    14161 aataatagcg caatgactgc tccaaaagta agtcgcttgg aaaaagagct cagcctgtta
    14221 attgatcttg tccaaggggt aggcgctatc tctaaagcaa caatgactca aggtgtctat
    14281 aagcttcaga caaccctacc tattccagag tattatattg gggttaatct ttatactgat
    14341 gatcagggga atattttatt tgtgcttgac atgagtgata cgattgggca gggacaactt
    14401 gatgactatg gcaatcctat tttaaatgtt gatgaggata atgaaggcta ccatgctttg
    14461 gccattgagt ccttagcaga ttacgaaggc cttacgatta aggatatatt gaccaaggag
    14521 ctaaatcaat tgcctattcg cgatgtcaag caagcaagag agcatcgtgt tggtcttttt
    14581 atggcaatca gagatgctgc aagggaagct cagcttctac tagaaaagca gagcaaagcc
    14641 ttatcagaat cagccggcaa atctaatggc tcaaaagtag ctgactcagg acttgagcct
    14701 tctgtgacac tatcaaccaa taagactaag ctgctaccaa aaacaggagc cttcaaagaa
    14761 gcttgggtga caatgatcgg aatgcttgtt cttttggcgg ctaccctact taaaggcgat
    14821 agtcgctaca aaaagaagta aataggcttg cttagcaagc acactctagc accagtaagg
    14881 cttgaggggc ttacaaagcc tatctaatct agcaatagta tattgccagt gtgagctggt
    14941 gcttgagctt caaaaaaaca aaagagcctg aaatgacttt tactagcatt tcaggctctt
    15001 tttagcttgt gattcttttt tgtgtgaagc ttacttctca cttatcgtaa tagtatcttg
    15061 atcaaggctt gctaataggt gtttagcagt cgggtgatcc aggtagtaat ccgtaatgcg
    15121 gtcacgaatt tcttgttcga tgacacgtct aagtggacga actcccatcg catgatcata
    15181 gcccagatca atcaaacgct ctttaacatc gtcagtcacc tcaaggctaa tgcctttttt
    15241 agcaagggtt tggttcactt ctgttagcat taaagcaaca atttcttgta aatccttttt
    15301 cgctaaatgg ttgaattcga tgacaccgtt gaagcgattc aagaattctg gtctaaagta
    15361 aggtgcaata cgctccatga tagcaggctc ttgatcagca cgatctcctg cttgatggcc
    15421 aaaaccagca ttagaggttg cgatgataac cgtatttttg aaattgatcg tgttgccttg
    15481 tccatctgtc aatcgcccat catcaagcac ttgaagaagc agtgtaatga cctgtgggtc
    15541 tgctttttcg atttcatcaa gcaagatgat agagtaagga ctgcgacgga cacgttctgt
    15601 aagggtattt tgattatcat catagccaac atagccagct gttgttccga ttaatttgga
    15661 aacagctgtg cggtcactat attcagacat atctaagcga atgatagcgt cctttgagcc
    15721 gaacatatca agggctaact gcttagccag ctcggtctta ccaacaccag ttggaccaac
    15781 aaagaggaag gagccaattg ggcgattacc gtcatcaaag cctgcgcggt tgcgtcgaat
    15841 cgcacgagca acagcctcaa ctgcaccatc ttgtccgata acatggcctt taagacggtt
    15901 actgatttcc ttgagccttt ctaaatcact agcccccata tttgatactg gaacaccagt
    15961 tagacgttca acagattctg caatatcatt aacagtggca gtgacctttt gcccttcact
    16021 gtgatgattg atttgctttt ggagctcctc aatgcgggtc ttagcagtta aggccttttc
    16081 aaagtcttct tctgcaacag ccttttcctg tagctccttt tgcttagtga tttctgcttc
    16141 aagtgatttt agatcagtga cagggtgctg agctgctaga tgagcagcag tcatatcaac
    16201 aaggtcaatg gctttatctg gtaggcttcg ttgtggaata tattggatag cataatcaat
    16261 agctgccttc aagacagagt ctggtaggat cacattgtgg tgctgctcgt agaggttgcg
    16321 aatgcccatt aaaatgtgga aggtatcctc tgctgaagga gcattaacct taacctcgtt
    16381 gaaacgacga gcaagagcag cattttttag aatggtgttg cgatactcat cttgagttgt
    16441 ggcaccaatc agggtcaact caccgcgtga gagggctggt tttagaatat cagctaagcc
    16501 cttagagcct gagtctgaac cagctgaccc tgcaccaagg atttgatgga tttcgtcaaa
    16561 gaagagaatg atattgccag cctccttaac ctctttaacc atgttttgaa tgttttcttc
    16621 aaaggagcca cgatactgtg tgccagcctc aaggccagaa atatcaattg agataatctc
    16681 tttatttttg atggcagctg gcacatcacc gttgacaata gcctgggcta ggccttcgac
    16741 aacagcagtt ttaccaacac cagcgtcacc gacaagaaca gggttattct tggttcgtct
    16801 tgctagaatt tctgcggtcg cttgaatctc atcgtttcgt ccgatcacag gatctaacct
    16861 gccttgccga gcttcttcgg tcaggtttgt tccgagcttg gttagaatgc cgtctttttt
    16921 aaggctgcta gcctgttttt cttgtccctc agctgcagct agcttaccgg ttttccggta
    16981 ttcttgaaat tcctctggtg tcatctcacg tccattgaca agatagcgac gattttcgct
    17041 gcggtagccg ccgatgtttc ccattaactg attgaaaata tcgtccatat tttcaaaggg
    17101 gtcttttcca taataggttg ccatatacac ttacctcact tgtattatat ttaccagtca
    17161 ttatgagcta ctggtatagg tagaaggtga tcggtgttgg ctcatacaga gatcatagag
    17221 aggtcttatg agagtctatt gctcaggctt attactcacc ttctaataat attatatcca
    17281 aaaggtcagt aaaggtcaaa caaaaagtat gaataattaa cctttataat caggtgctta
    17341 tagcccttga aacatcagat gactatgcca taagctgctg gtgctttttt gctagcaagg
    17401 ctatctgtaa agaagagact tttgtcaaaa atggttttac tttttgttct aaaggctttc
    17461 atgatataat aaaagaaaag cacagaggtc aattatggaa caaacatttt ttatggtgaa
    17521 gcctgatggt gtgaaacgtg gcttggttgg agagattcta cgccggattg agcgtcgtgg
    17581 ctttaccttt gataggcttg aattgcgaca agcaacccca gaattgctag ctaagcatta
    17641 tgacacctta atcaataagc ccttttatcc agagctagag gcctatatga caagcggacc
    17701 tgttttaatc ggcattatct ccggtaatcg tgtggtctct tcctggcgaa ccatgatggg
    17761 ggtaaccaat cctaaagacg ctttaccggg gactattcgt ggtgattttg ctcaagcccc
    17821 tggtgatgat ggcggcattt tcaacgtggt gcatggttcg gattcgagag attcagccaa
    17881 gcgagaaatt gcgatctggt ttggacatag ctgacattgg gcttgggcct attcttttaa
    17941 gaactgataa agcaattgca taaggggttg ataagcccat catcaatagt agctcagcat
    18001 tagaagggta acagccttga tgttgggcta tttttttgct tgcctagggt ctgtatgctt
    18061 gtcctgatga gcaggtagac aaagcagcat aagtttaaca atcctttgcg gcagtgatca
    18121 attgtagctc taaccatagc atcagctatt tgaaagcctt gaaaaagaaa gctaaggcta
    18181 acaagctagt ctaggtcatt tactacaagc gacttttttc aattagctgc tcaaggcaag
    18241 tattgaaaaa agtccatttt tcatgtcatt tgtaataata tggtatattt ttaacgaaaa
    18301 gtcgttttag ttgagaaaat atacaaaaaa ggctatgata tagttaataa agttgttata
    18361 ccccctgtgt cttgtacact atgacttgta gagagtttat caaaggagga taagatgaac
    18421 aaacaaagca tgacccattt ttctaagaag ctgatgaagt tagccctttt aggtttggca
    18481 ttgccattaa gcttggtgtc ggtggtagat actccggttc ttaaccaatc cgaaaaagct
    18541 gtttatgcca atgattttgg atctggaaat cgagccagtg attatgtacc ggcggctaac
    18601 gcttggagct ttgaggctta tccagattac tacagtattt taggagctag tcatcttaat
    18661 cctgctgtct ttccagagcc tagtaagatg tcatacagtc ctttagacga gttgggccgc
    18721 acacaggtcg caagaggaac aataacctat cacaatatcg tgatgaatta caatgttcgg
    18781 caacgctttg ctaaaaatca gaacccttca ggctggattg gtaaccctag aaatgttcgc
    18841 tacactattg agtggctaga tggactatcc tatcagggag atttttggaa tcggagtcat
    18901 ttgattgcag atagccttgg tggagcagcc ttacgtgtca atgctattac tggtacaaga
    18961 acacaaaatg ttggcggcag aaatcaaaga ggcggtatgc gctatattga gcaaaaggtg
    19021 cagcagtgga ttgagcagca tacaagcgca gttgtttatt acgaagcggt gccaatttac
    19081 caggcaaatg agctagttcc aagagctgtt gttgtttcag cattgtcatc agacggaggt
    19141 cttgacgaaa aggtcatggt ctataatacc gccaacggct ataccattga ttatgccact
    19201 ggcgcattcc gcagtaacta ggcttttgta ctaagctgta gctgatcaag gtctgactaa
    19261 gacaagctca tcagcaattg gtatataaaa agacgtggca acaacatgtt ttaaatgagt
    19321 tgtcatgtct ttttagtgtc gtcagctttt cacattgtct tagaatgatc acacctagct
    19381 agccgctaaa agcattggtc caaagaaatg ttaagaatag atagaatgcc ttttaatcag
    19441 tggtatggga ctgctagcta atataatgcc tgcagttgag ccaatttctc atctaggcta
    19501 ataactaaca agctattgac ttatcgtgtt cattagaatg tcagctgttg tagttggtag
    19561 tattcgaata cgattaagcg atagcaggcc attagcagca cttgctagtc cttcatttgt
    19621 tgtgacccct aatttgtaat gcagatcctc agcaatcttt aatgtggtat cagtataacg
    19681 acctgctgga taggcaattg caatggtatc ttggtgtagc tctctatcta ggtattcttt
    19741 agaatctttc atttcagcgg tttgactagc agcgcttgcc tgagatagat cagggtggtt
    19801 aaccgtatga tcttggaaag acatgcctgc ctgcttcatt tccttcatct gatccaatgt
    19861 aagattggcc gcattacctg cctctgtaaa gccagtgata acgttattgg tggccttgat
    19921 gtcatacttt ttcaggattg gaaaagcaac gttgtaaaaa tcaaccatgc tatcatcaaa
    19981 ggttagccag acaacctttt cagcaggaag ctcgttagct gataagactc ggtaggcttc
    20041 ttcgggagat aaaaagtagt agccggcctc cttcattgcc tttagctggc tttcaaaaag
    20101 atctggagca acgatgagat tggcacttgc tgcctcttct ggtgccataa cgtgaatagc
    20161 atgatacatt aagataggaa gcttaacagg gttttgctgc ttggtccagc tgacagctcc
    20221 tttttgctgc tgactatttg tatggctagc ttccttatta gttgcttttt tgctaggctt
    20281 gggagctggt tttttatcag tttttgaaaa taggcttatt ttggggattg cctgcgataa
    20341 ttgagagatg cttatctttg aatggctctt gtaaaggtag acaatagctg ataagcctat
    20401 gatacaggca agtagtagca tgagattaat cattttgaag atttttcttt tcttacgccg
    20461 tttgtttctg ttgttcatca cttgctcctt gtttattgat tagtctattg taacattttt
    20521 ttaagtaagc tgtctttcgt taacttaatt ttttgctaac attctattag tgttatgctt
    20581 tgtaaaacaa gacctagatt tgctataata agacagagta tttaagacag tcaaaaaaag
    20641 gaggatagga tgtcagttaa ggttgcatta ttaggctttg ggactgttgc tagtggcatt
    20701 cccttgctat tagaaaacaa tagtagcaag attcgtgcag tggtaggtga tgatttggtg
    20761 attgcaaagg ttctggttag agatgagacc actaagaagc gtttgttgga tcaaggctat
    20821 tcctaccaat ttgtgacctc cattgatgat attgttgatg atgagagcat tgatatggtg
    20881 gtcgaattaa tgggtcgtat cgagcctgca aagaccttta tctcgcgtgc tctatcagcc
    20941 ggaaagcctg ttgtgactgc taataaggat ttgatagcct tgtacggagg agagctctcg
    21001 actttggcag ctaagcatca ggtagctttg tactacgagg ctgctgttgc tggtggtatt
    21061 ccaatactaa gagctttggc tgattccttt gcctcagata agctgacgcg tctgctcggt
    21121 gtgctcaatg gaacaactaa tttcatgtta accaagatga ttgatgaggg ctggacctat
    21181 gaaagggccc tgcaaaaagc gcaggagctg ggctatgctg aaagtgatcc gactaatgat
    21241 gtgaaaggga tcgatgcagc ttacaaggtt gctattctta gtcagtttgc ttttggaatg
    21301 accattgact ttgaggctat tagctattca gggattgata aggttcgagt agaagatgtg
    21361 acagtagcgc agaagctggg ctatgtgatc aaattagttg gtctacttga agagacggct
    21421 tctgggctta acgcagaggt atccccagtc tttttaccaa agacacaccc gttggctgct
    21481 gtagacggtg tgatgaatgc tgtttatatc gagtcaattg gggttgggca ggctatgttt
    21541 tatggtccag gtgccggtca aatgccaaca gctacagctg ttgtggcaga tatgattcag
    21601 actgcctgca ccttacgtga ccatacagtc tcagtcttta atcgttttgc tacaaaaact
    21661 agactagcta agtctgagga tattatgagt ccctattact ttgctattca agcaactaat
    21721 aagtttggtc agctactaga gctaacaagg ctatgtgatg tttgtggcat tagagttgag
    21781 cagctgttat cagatgagat agatagtgac aggttagact ttgtgatgat tactcatgag
    21841 atgagcaaaa aggagcttgc ttgctttaca gcgctactac aggatcatca ggatttccgt
    21901 atgttaagta catttaagat tttaggagat tgacatgaag atacgcgtac ctgcaacctc
    21961 ggctaatttg ggacctggat ttgactcaat ggggattgct gtttcaaaat acctagaagt
    22021 tgacatttta gaagaacgtg accaatggtt tattgagcat gatttgggtg atattccaaa
    22081 tgatgatagc aacttactta tccaaacagc ccttaggcta gcaccaaata ttccagcaca
    22141 tcgtctaaag atgacgtctg atattccatt ggcacgtggc ttgggatcgt cctcctcggt
    22201 gattgtcgct ggtattgaat tagctaatca gctagggcat ttaaacctaa cagacgaccg
    22261 taaattggcc atagcaactc gtattgaggg gcaccctgat aatgtagctc cagcgatttt
    22321 tggtcaattg gtaattgctt cacagattgg taaggacgtg gattacatca ttgcgccttt
    22381 tcctgacctt tctttggttt gttttattcc tgattatgag ctgaaaacct ctgattccag
    22441 agatgtattg cccaagcagc tatcgtataa gcaggcagtg gctgcttcct cagttgctaa
    22501 tcttgctata gctgcgctat tgaccggtaa tttgaaaaag gccggtcggg cgattgaaaa
    22561 tgaccaattc cacgaaatct accggcaaag attagtcaga gagttccagc cgattaagcg
    22621 agctgcagca gctaatggtg cttatgcaac ctacttatcc ggtgcagggc ctgctattat
    22681 ggttatgtgt cccaataaga aaaaaatggc gatttatgag gccatcgagc agctaggtct
    22741 aattggtcag ttggtgtctc tagagctgga tcgtcagggg ctgtgtcttg tctagactgg
    22801 caaggtactg gtatgcttgc ctagtaggct tattgttgat atcagatgga cttaaagctt
    22861 agtcattcaa atacatcaaa aaagtgaggc ttgatcgttt tatcggcttt cacttttttc
    22921 ttgatatgtt atactagagt agactttgtg aggtgtgtga tgaattatca agaaacatta
    22981 gactggattc atggtcagga aagatttggg atcaagccag gtgtaaaacg catgcgttgg
    23041 gtgcttgagc agctaggtaa tcctcaagat aggattagag gaatccatgt ggtcggcaca
    23101 aatggtaagg gatcgacggt caatgaccta cagcatattt ttactagagc aggctatgag
    23161 gttggaacct ttacctcgcc ttatatcatg gattttaagg aacgtatctg tctcaatggt
    23221 gagatgatct cagagactga ccttgttaag gctgctaatt gtattcgtcc actaacggat
    23281 cgccttatca gtgagacaag tttgggtcct gcaacagtct ttgagctgat cactctgatc
    23341 atgtttcttt attttggtga gagtcacccg gttgatattg ctattatcga ggcaggatta
    23401 ggggggcttt atgactccac taatgtgttt caggcgatgg ctgtggtttg cccgtctatt
    23461 ggtcttgatc atcaagctat tttaggtgat acctatgctg acattgccta tcaaaaagcc
    23521 ggtgtgctaa agggtggtga agaccttatt tttgccattg ataacaaaga ggccagacag
    23581 gtttttctaa aaaaagcaga gcagcttggc gtgcctattt gggaatggcg tcgacagttc
    23641 aacatgctac agggtgaagg tggttatcaa tttaacagtc agcttggtca gctgtctcat
    23701 ctagtgcttg caatgcctgg tcagcatcag gtagccaatg caggcctagc cactatgaca
    23761 agcttgatat tacaggatcg gtacccaaag gtaactgagt ctgttattag agaggctctg
    23821 gcaagcagct tttggttggg acgaacagaa ttgttggcac ccaacctgat gattgatggt
    23881 gctcataata atgaaagcat tgccgccctg attgatgtga tatcatcaga ctatcaggat
    23941 aagcagattc atattctatt tggtgccatt gataccaagc ctgtctcaga tatgctgcag
    24001 agtctggagc gtcttggaga tgtgcaagta acaagctttc actatcccaa tgcctatcct
    24061 ttggaggctt atccagatag gctaacaaaa gtagcagatt ttagagcatt tttagaccgg
    24121 cttgagcaag cagctgctga tgattttttc ctgattacag gctctcttta cttcatctca
    24181 gaggtcaggc agtattggaa aaaggtatta agcaagtaat gctttctcac atcaactcat
    24241 caaacaagat taatcaacta aaaaggggaa aaccattgcc aatcaatcaa aaaaaagcag
    24301 aagccgctat ctatcaatta ttagaagcta tcggtgagga tccaaaccga gaagggctac
    24361 gagatacccc aaagcgtgtt gccaagatgt atctagaaat gctctcaggg ctggaacagg
    24421 acgctaagga tgaatttaca gctgttttta cagagcatca cgacgatttg gtgattgtta
    24481 aggatattag cttttattcc atgtgtgagc accatctggt gccattttat ggtaaggcgc
    24541 atattgctta tttgcctagt gatgggcgtg tgacaggctt gagtaagctg gcaagggcag
    24601 ttgaggtgac gagcaaaaga cctcagctgc aggagcgttt gacagctcag attgctaatg
    24661 ctcttgttga tgccttgcag cccaaagggg tttttgttat ggtagaagca gagcatatgt
    24721 gcatgaccat gcgaggtgtc aaaaagccag gcagtaagac cattacgaca actgctagag
    24781 ggatttacaa ggatagtaga gacgacaggc gtgaggttat gcaattaatc atggagggct
    24841 agggtattta tgactattgg acattattca gccgctggtg aggcagctat tatggggatt
    24901 ttaaatgtga ctccggattc gttttcagat ggtggctcct atactagtgt taatcaggcc
    24961 ttggcacagg ccgaaaaaat gctgtcagaa ggagcgactg tcattgatat tggaggcgag
    25021 tcaacacgac cgggctgcca atttgtgccg gcagaagaag agattgcacg cgttgttcca
    25081 atcataaagg ccattaaaaa acggtatgat gtccttatta gcattgatac ctacaagaca
    25141 gaaactgcta gagcggccct tgaagcagga gcagatatgc tcaatgatgt ctgggcagga
    25201 ctatatgacg gtcaaatgct aagtctagcc gccgaatacg acgttcccat tatattaatg
    25261 cataatcaaa ccaaagaggc ttatgctgat gttacaaaag aggtttgcag ctttttacag
    25321 gctagagcag ctgcagccct caaagcaggt gtcaaaaaag aacatatctg gcttgatcca
    25381 ggatttggct ttgctaaaaa tgttgagcaa aatatagcct tattaaaagg gctaaatgag
    25441 gtttgccagt tgggctatcc tgttcttttt gggatttcca gaaagcgtgt tgtagacgcc
    25501 ctacttggtg gcggcactaa agccaaggat cgtgacgggg ctactgccgc cctatcagcc
    25561 tacgctatta ataaggggtg tcaaatggtg cgcgtgcata atgtcggtgc taacagggat
    25621 attgtctctg tattgagtca attaaggtga gaaatgatgg ataaaatcag attagaggct
    25681 tgtcgctttt atggttatca tggtgccttt aaggaggagc aggtcttagg tcaaattttt
    25741 gtagtggatt tagaattatc agttgacttg atggctgcct ctctttcaga ctgcctagag
    25801 gatactgttc attatggttt agtttttgaa acagtccgtc aaattgttga ggaaaagacc
    25861 tttacgctta tcgaacgttt ggctggtgcc atttgtcaag agctatttgc ccagtttttg
    25921 cctattaaag cgattaaaat cgctattaaa aaagaaaatc caccgattgc aggccattat
    25981 caagctgtcg gtattgaatt ggagagaaag agatgacact tgtttattta ggcttgggaa
    26041 ctaatatggg agatagggca ggctacctac aggcagcagt taatgcccta tctaagctgc
    26101 cagagactga gttactgaga caatcctcta tctatcaaac agcagcctgg ggaaaaacag
    26161 atcaaaatgc ctttttgaat atggcttgcc agctagatac taggctgaca tcagaagctc
    26221 ttttggcagc tacgcaggct atcgagcagg ctctgggacg agttcgtcat gaaaaatggg
    26281 gcccaaggac aattgatatt gacctcttgc tgtttggtga tgagccgtat caatcagaga
    26341 ccttggttat tcctcaccct tacatgacac aaagagcctt tgttttgatt cctttattag
    26401 agattgcacc cgatgtgacc ttacctggta gccagaaaag cctgaggtct taccttgatg
    26461 ctttagagca atcagatgta gccttgtggt cacatgagta ttcaaataag ttttcttaaa
    26521 ctgtcgttat ttttactaaa atttgatata atagtgctac tctttgctga ttttttgtct
    26581 tatattaaga aatgattgaa gaaagaagaa gattatgata gctgaacttg aaggcattga
    26641 tattcgagag aatgaagcct taaaacatta cacctatacc caagtaggcg gtccagcaga
    26701 tttcttggct tttcctagaa atcattacga actatcccgt attgttgatt atgccaatca
    26761 taatcatatt ccttggatgg tccttggaaa tgccagtaat ctcattgttc gagacggtgg
    26821 tattcgtggc tttgttatca tgtttgataa gctcaacgcc gtccgcctta atggttatac
    26881 cttggaggca gaggcaggcg ctaacctcat tgaaacaaca aaagttgcca aatttcatag
    26941 cttaacaggc tttgaatttg cttgtggcat tcctggaagc atagggggtg ctgtttttat
    27001 gaatgcaggt gcttatggtg gagagattgc tcatattttt ttgtcggcca aggtcttgac
    27061 accagaaggg aaaataaaaa agatctcagc cagagagatg gcctttggct atcgtcactc
    27121 tgtcattcaa gaaactggtg atattgtgat ttcagccaag tttgctttaa aaccgggtaa
    27181 tcatgacagt atttgtcagg agatgaatcg cctcaaccac cttcgaaagc tcaagcagcc
    27241 cttagaattt ccctcttgtg ggtccgtttt taagcgtcct cctgggcatt ttgcagggca
    27301 attgattatg gacgctaacc taaaagggca tcgtgttggc ggtgttgagg tctctaaaaa
    27361 gcatgcaggc tttatgatta atgttgctga tggctctgcc aaggattatg aggacttaat
    27421 tgctcatgtc attaggacag ttgagcaggc atctggcgtt aggcttgagc cggaggttcg
    27481 tattattggt gaaagccttt aatgattgtg ttatcaaaaa agaaaaattg tggaggattt
    27541 atgacaattg actaagccaa ttatcacatt tgacaatgtc tcaaagacat ttgaggacag
    27601 cgggacacag gtcctaaaga acattaattt tgagcttgag gagggaaaat tttacaccct
    27661 gcttggtgcc tcaggatctg ggaaatcaac cattttaaat attatggctg ggctgcttga
    27721 tgcgaccagt ggtgatattt atttagatgg tgagcgtatc aatgatttgc cgaccaataa
    27781 gcgtgatatt cacactgttt ttcagaatta tgctttgttt cctcatatga cggtttttga
    27841 gaacgttgcc tttgctttaa agctgaaaaa ggttgacaaa caggagatag caagacgtgt
    27901 caaggaaacc ttaaaaatgg ttcagctgga gggctacgaa aagcgatcca ttcaaaagct
    27961 ttccggtggt cagcgtcagc gtgtagcgat tgctcgtgcg attatcaatc agcctcgtct
    28021 tgtcctatta gatgagccac tttctgccct tgatttgaaa ttgagaacag aaatgcagta
    28081 tgagctgcgt gagctgcagc agcgactggg cattaccttt gtttttgtta cccatgatca
    28141 ggaagaagca ctagcgatga gtgattggat ttttgtcatg aatgatggtg aaattgtgca
    28201 atcaggcaca cctgtagata tttacgatga gccgattaat cattttgtag ctagctttat
    28261 tggtgaatca aacatcatca atggtacgat gattaaagac tatctggttt cctttaacgg
    28321 gaaagaattt gagtcagttg atggtggtat gcgacccaat gagccagttg aggtggttat
    28381 tcgaccggag gatttacaaa tcaccctgcc agaggaagga aagcttcagg taaaggtaga
    28441 tacacagctc tttcgtggtg ttcactatga aatcattgcc tatgatgatt taggcaacga
    28501 atggatgatt cactcaaccc gcaaggccat tgaaggagaa gtgattggtt tagatttcac
    28561 accagaggat attcatatta tgcgcctcaa tgaaacagaa gaagaatttg atgctcgtat
    28621 cgaagaatac gttgaaatcg atgagcatgc ggatggctta atcaatgcta ttgaggagga
    28681 gcgcaatgaa gaaaacctct agcctctttg cagttcccta ttttttatgg attgtcctct
    28741 ttgttatggc accggttgcc cttttgcttt atcaatcctt ttttgacatc gaaggacgat
    28801 tgacactagc caattacgag acttttttta gctcatggac ttacctgaga atgggcttaa
    28861 actctatctt atatgctggt atcgttacct tggtgacctt tttgatttca tatcccacag
    28921 ctttattgtt aacgcgttta aagcacaagc agctgtggtt aatgcttatt attttaccaa
    28981 cctgggtcaa tctgctcctc aaggcttatg cttttatggg gatttttggg cagcagggtg
    29041 gtatcaatag ctttttaacc tttatgggct taggaccaca gcaaattctg tttactgatt
    29101 tttcgtttat ttttgtggcc tcttatattg agctgccctt tatgattttg cctattttta
    29161 atgctttaga tgatattgat gataatatta tcaatgccag taaggacctg ggtgccaatg
    29221 actaccagac cttttcaagg gttatctttc ctttgtcgct aaacggtgtt agagcagggg
    29281 ttcagtctgt ttttattccc agcttgagtc tctttatgct tacgcgtctc atcggtggaa
    29341 atcgtgtgat tacgctgggg acagctattg aacagcattt cctaacaaca gaaaactggg
    29401 gcatgggctc aaccataggt gttgtcctaa ttatcgcgat gattgtgatt atgtggctaa
    29461 caaaggagaa aagtaaatga aaaaatttgc caatctttac ttagcgtgtg tttttatttt
    29521 gctctatatt ccaatctttt acttgattgt ttattctttt aacaagggtg gagacatgaa
    29581 tggcttttct ggcttgacgc tagagcatta taagaccatg tttgatgata gtcgcttgat
    29641 ggcgatttta ttgcagacct ttgtgttagc ctttacaagt gccttgcttg caaccattat
    29701 cgggaccttt ggggcgattt ttattcatca gagtaaaaag aagtaccaaa atgcgatact
    29761 gtctgcaaat aatgtgttga tggtttcccc tgatgtgatg ataggtgcct ctttcttgat
    29821 tctctttacg tccttgaaat ttcaattagg aatcctctcg gttttgatga gtcatattgc
    29881 tttttccatt ccgattgtgg tcttaatggt gcttcctcgg ttgaaggaaa tgaatcaaga
    29941 tatgattaat gcagcttatg atctaggagc aaatcacttt caaatgctaa aggaggttat
    30001 gcttccttat ctgacaccgg gcattatcgc aggctacttt atggccttta cttattcctt
    30061 agatgatttt gcggtgacct tttttctaac aggaaatggc tttacaaccc tgtctgttga
    30121 gatctattcg cgtgctcgaa ggggtatttc attagatatc aatgccttat caacgattgt
    30181 ctttttgttc tcaattctat tagtcattgg ctattattac atttcacagg acaaggagga
    30241 aaagcatgcg taagctatac tcttttttag cgggaattat cggggttatc ttgctgcttg
    30301 cgaccctgtc ctttattttg cagaaaaaaa cgagctctgc tagtcaatct gataagctgg
    30361 tgatttataa ctggggtgat tacattgatc ccgctttgct gaaaaaattc actaaggaaa
    30421 ccggtatcga ggttcagtat gagacctttg attccaatga agccatgtac accaagatca
    30481 aacagggtgg aacgacctat gacattgctg ttccgagtga ttacacgatt gacaagatga
    30541 ttaaggaaaa gcttcttgtt aagctagata agtccaagct tgttggtcta gataacattg
    30601 gtcaggagtt tttaggaaaa agctttgatc cgcacaatga ttattccatt ccttattttt
    30661 ggggaacggt aggcattgtc tataatgacc agctggtgga taaggctcct atgcattggg
    30721 aggatttatg gcggccagaa taccaaaata gtatcatgct agttgatggt gctcgtgaga
    30781 ttttaggtgt tggattgacc acatttggct atagcgttaa ctcaaagcac ctaaagcagc
    30841 ttgaagcagc tgaaaaaaaa ctacaggcct taacccctaa tgtaaaagca atcgtcgctg
    30901 acgagatgaa ggggtatatg attcagggtg acgctgctat tggtgttacc ttctcaggag
    30961 aggctagcga aatgctggac aataacgacc atctacacta tgttgtacca tcagagggct
    31021 caaacctttg gtttgataat ctggtgcttc ccaaaacaat gaagcatgaa aatgaagcct
    31081 atgcctttat caactttatc atgaagccgg aaaatgcagc acaaaatgct gaatatatcg
    31141 gctatgccac tcccaataca aaagcgaagg ctttattgcc agatgatatt aaaaatgacc
    31201 cagcctttta cccaactgac gagaccgtaa agaaattaga ggtttatgat aatttaggct
    31261 ctaaatggct tggtatttac aacgaccttt acctacaatt taagatgtat cgaaaatagg
    31321 tcatgcaaga ttgaaggagc tattcattgg aaagcttctt cagtcttttt tagcttggtc
    31381 tggtctcaat aatctcatga gattaaaaag aactagaatc ttgctttcgt ctttgataca
    31441 atagtagtgg tttattaaaa tgaaagagat gacaaaatgg aaaatcataa aaacgagttt
    31501 accttttcca aacattcaat catagcctac gtttggcgtg gcattttagt cgggataatt
    31561 gctggagcta ttgtcagttt gtttcgctta ttgattgaga tggttagtga ggctgttgtt
    31621 ggctattatc accaagctca cagcaatcgc atgctccttg ttccgatagc aggctttagc
    31681 ttattagctg tttttttagt tggtcttttg gtcaagtctg acgccaacat taaaggctct
    31741 ggtattccac acgtcgaagg ggagctaaag ggcttgatgt cacccaattg gtggagtgtg
    31801 ctttggaaaa aataccttgg tggaacaatt gccatttcta tgggcttaat gcttggaaga
    31861 gaaggccctt ctatacaatt aggggctatg tcagctaaag gcttagctaa gtacctgaaa
    31921 tctagtcgtc tagaaaaacg tgtcttgatc gctagtggag cagctgctgg cttatcagct
    31981 gcttttaatg cgcctattgc aggactgctt tttgttgttg aggagattta ccaccatttt
    32041 tcaagattag tgtggatcac tgccttggtt gcaagccttg ttgcgaactt tatttcgttg
    32101 aatatttttg gccttagacc tgttttggcc atgcctaagg ccatgccctt tcttgcctta
    32161 catcaatatt ggctgctctt aatcttaggc cttgtgcttg gctgtctggg ctttctttat
    32221 gaagaggtca ttttacattt tcatagggtt tatgattttc ttggaaagag cttgcgccta
    32281 gcgccgcatt ttcatgggct gattgttgtt gctattatcc tgctgattgg ctattatttg
    32341 ccacagctat tgggcggagg tcatggtttg attatgtcct tgtcagagca aaagctacca
    32401 ctgttgactg ttcttgctta cttctttatt cgatttttag ggagtatgtt tagctatggc
    32461 agtggcctgc ctggaggaat ttttttgcct attctaacct taggtgcctt gtccggaact
    32521 atttttggat tgattcttca gcaaatagga ctgttagatc gccagatgat tcctctcttt
    32581 ttagtattgg gaatggcagg ctactttgct gctgtatcaa aggcaccctt gacaggaatg
    32641 atcttagtga ctgaaatggt aggggatctg aagcccttaa tggccattgc tgttgtgacc
    32701 ttcgtggcct acttggtgat ggatttgtta aatggtcagc ctatctatga agcaatgcta
    32761 gagaaaatgg ctatcaaaca cccaacagat ctagtggagc cgaccctgat cgaattacct
    32821 gtaagtgaga aaattgcagg cagatatgtc cgagacctga agctacctaa aaacgtttta
    32881 attacaacgc agctccacca taagaaatca caggtcgtct caggtgatac gctattgatt
    32941 tcaggtgcta cgatcttttt ggtggtcaat gaagctgata caggctttgt tcgagaggtc
    33001 ttgatgtaga gcaaggtcgg ttaagcagtc agcagtagct gtgctaccga tcaaagaagc
    33061 agatcagtgc tttttctcat ctgatgaaag gtattgattt gctttttttg tgttattaaa
    33121 cctttgttag caagagccat agccttagca gtcgtatctg atgaatacct gctgtctttt
    33181 tgttatactt aagtatcaat caaaggagct ttatatgcta gaagttattt caaaagagct
    33241 gcgccattac caaaagaata agcttgccgc ctatcaaaaa aagaaccaag gcatagaagc
    33301 tggtggaatt gtttttgctg gcgattcgtt aatcgaattt ttcccgttga aaaaatattt
    33361 caaacaggtc tcaaccattt ataatcgcgg aattgcaggg atagacagtc agtggttgct
    33421 agagcatatt gacagtcatg tgaatgatct ggagcccagt catgtgttta tcctgattgg
    33481 ctgtaatgat attgggcttg gctttgatca atcgcatatc gtatcgacca ttgttgatct
    33541 tattagtcgt attcgcagtc agtctattta tactaggatt agccttctgt ccttattgcc
    33601 ggtttctgaa aatcccgcct atcaggcgac tgtcaagcta aggacaaata gggctattga
    33661 tgagattaat caagcattag caatgatacc agcgattgaa tttattgatc ttaacgcctg
    33721 cttaaaggac gagactggtg gcttagcagc tgcttatacg gtagatggca ttcatcttaa
    33781 tgcccttggc tatgaacact tagctcaagc tattagtccc tatctatgaa aggtaaaggc
    33841 tggagctgct aatttgtaag ggatctttaa aaaacaagca ctgatgaatc atcattgaaa
    33901 cccttcagag tgccgatagg ctgcacaatc aaagaagcat taggtttgtc tatgacgccc
    33961 ttgtgttaag ctggctttta ggtttatact gcgagaaaat cagtcattgg gctgggagtc
    34021 tcaaagctta gctgtggtaa ttaaatgcga gctcctgcta gcttgtgctg atcaagcagt
    34081 atagcaagga gggactgaac ttttagtctc agataatatt agacttttta tcctatatta
    34141 aacgatttag tgtataataa acaggaagga gttaaaatga aatttgaaaa aaaacaagtc
    34201 ttttatgttg tgcttgcctt tgtgctttgt tatgctattc aagctaattg ggataatggg
    34261 gctaatattg tcacaaccgt ttataagaca agcctgccct ttctttatgg agcagcagtc
    34321 gcctatattg ttaatattgt catgagtgcc tatgaaagag cttatactta taccctaaaa
    34381 ccctttcctt ttgccatgaa ggctagaaga gggctctgta tgcttttggc atattttacc
    34441 tttatcagct tgatcgtatg gattatttct attgtaatcc ctgatttgat tgcaagcatt
    34501 agctcgttaa cgcaatttga tacaagagct atcaaggagg tcatcagtga tttaggtcac
    34561 aataagctga ttgcacgtgc cattaattac attggtggag atgctaagct gacagaaaca
    34621 attaccaatt atagccagca gctgctcaag caatttatag gtgttctaac cggtattttg
    34681 acatcggtta cagcagttgc ctcagccatt atcaatgtgg ttatcagctt tgtcttttcc
    34741 ctgtatgtgc ttgctagcaa ggaagagctt tgtcagcagg caactacctt aattgacacc
    34801 tatactggta aatacgcaaa ggccattcat tatttagtgg gtttgctgca tagtcgtttt
    34861 cgtggcttct ttgtgagtca gacgcttgaa gcaatgattt taggctcctt gactgccatt
    34921 ggcatgttta tcctgcaatt accctttgca ggaactattg gagtcttggt tgcttttact
    34981 gccttgatcc ctgttgttgg tgcttcaatc ggtgctgcga taggctttgt tttgattatg
    35041 actcagtcaa tgtcgcaggc agtcgtcttt attgtctttc ttgttatact acagcaaatc
    35101 gaggggaatt ttatttatcc cagagtggtt ggtgggtcta tcgggttacc agctatgtgg
    35161 gtcttaatgg caatcaccat tggtgctgct ctcaaaggca ttgttggtat gatcgttgca
    35221 gtgccattag cggcaacgct ttatcaagtg gtaaaggatc acattcataa aaagcaggcc
    35281 ttacaaaatc gtcagtccag ctaattaaca gcatcagatc aaggaaaacg tctattacaa
    35341 gaccgatttc ttggtctttt atgctgtctg attgactgcg tatggcctta tttttatgct
    35401 gtggtaatga aaaaagccgt cttatttatc gaatatcatt agtggaggta ataagatgta
    35461 ttccatcaaa actgatcata aattaatgcc tagagagcgt ttgattcgac tgggtccaga
    35521 aaagctaagc aatcaagagc aactagcgat cctacttagg acaggtaaca aggaaaagca
    35581 tgtcttagag ttgtctgctt atttattgtc aagcttagat agtctagctg acttgaagaa
    35641 attttcttta caagaactac agcgcttatc cgggatagga aaggtcaagg ctattgagat
    35701 taaggccatg ctggagctgg cagaccgtat tcagatagcg ggacaagcag tagcagatcc
    35761 tgtcttatct agtgctcagg tggctgaaaa gatgatgatt gaattaggag acaagcagca
    35821 ggagcattta gtcgctattt atctcgatag tcaaaataaa atcattgaag aaaagacgat
    35881 atttatagga accgtcagaa aatcaattgc agagcctaga gaaattcttt attatgcgtg
    35941 taaaaatatg gcgactagcc ttattgttgt tcacaatcat ccctcaggcc tgaccaagcc
    36001 aagcgcaaat gactatcact tcacagaaaa aataaaacga tcatgtgatt atttaggact
    36061 tatctgccta gatcacatta tcgttagtaa gtatgactac tatagctttc gggaaaaatc
    36121 agatttattt tgagttagaa actatggata aaccaatcaa agagccttag gtcttcttct
    36181 ctaatagcct gaagcagctc tgggtgccac tggacaccga gaaagggaat atcaggattg
    36241 caggagataa cagcctcgat ggtgccatcg ttaggatccc ttgcaatcac tcttaagtcc
    36301 tctgcgacct gctttaggct ctggtggtga aatgaattaa tcagcgctct tggaccatag
    36361 atagggtaca aaggtgaagt cttttcgatc actatctcct gtgataaaca gtcagaggca
    36421 gtcttttgcc aatggccctc aatgtgctgg tttagactgc cacctagagc aacatttatt
    36481 aactgcatac cgcgacaaat ccctaaaatt ggttttttct gcgctagggc ttctttaatg
    36541 atggctagct caaagatgtc acgctggggt gaaaaatcac catcaagtgc agctcttttt
    36601 tcatgataat atttaggatc aacatgctga ccaccaataa gaatgatttt atcaaccatt
    36661 gcgacatagg atttggcagc cgcctcatcc ccaatcggaa gaagtaaggg taggccacca
    36721 gatcttgtca cagcctcgat gaagcttgtt ggagcatagg agcaaggcag gttatctaga
    36781 gccttggtcc ccctttggtt agcagttatc ccaataattg ttttagacac gaccttctcc
    36841 attaatcaag atgattttgg ttcataaagt atagcaaggt ttgcaactcg ctggtcaaat
    36901 caacagattg gacgatcaca ccttttggaa cctgtaagtg aagtggagca aagcttaaaa
    36961 taccgcgaat gccagcttca atcagttgat ctgcaacctc ttgagcatag atgcttggga
    37021 ctgttagaat agccgtttca atgcctgaat tatccaggtg ctccttaatg gtagaaatgc
    37081 cataaatagg aatatcatca ggcgttttgg tgccgaccat aggattatca tcagtgtcaa
    37141 atcccataac aatctgcatt ttgtttcgat cgtggaagcg gtagtgaaga agtgcacgac
    37201 caatattgcc gcagccaact aaaatcacat gcgttgttga gtgatcattt agcaaatctg
    37261 caaaaaaatt cattaatttt gtgacatcat agccaaatcc acgtcggcct aattcaccaa
    37321 agtaagaaaa atcacgtcga acagttgcag aatcaattcc catagcatca gcaatctgtt
    37381 ttgagcttgc cttttcaacc tgatcagcat aaaagcgttt aaaaatacga taatagagtg
    37441 ataagcgttt tgcagtcgct tttggaatag atttatcaat aaccactttt gtagctcctt
    37501 ctattgttat tttaatgtta tctatcacca ttgtagcaga tagattgtga aatatgcaac
    37561 tatttgacca ttctttttgt gtttttcgtt ataaaatgac ttgacagcac aagcattggt
    37621 atttttcaaa cccagtcacc tcgagtataa aaaagcagac aatgaagcac ttgcccttta
    37681 ggtcagctgc gatggctggg cttgtcttgt taaaggcaaa tgtactgtca ttgtctgata
    37741 tttctctgag attagaagag ctcttgtgtg cttagcattc ttttttaatg aaaatatcac
    37801 gctcaacaag gctatccatt aaaaagtaaa acttgtcctg tagtatgcta tgctcttcag
    37861 atttaaaaat gttcaccagt cttagaccgg attggtctgt tatagctagc ttaaagccat
    37921 ctaaatcttt attaatcgta atttttaaag ggaagccctc acccgaatta gggacttttt
    37981 ccagtagtcg tgttaactga tagtgaccaa tcttggtctg actaaaggtt gtgtctctta
    38041 gggtgtattt tttaatcttt gggctaatcc tgtagctgta tttgcagtct ttaagggcaa
    38101 tttctttttc aaatgccata tgatcctcct aaaatatttt tgagctgggt tgctagtgcg
    38161 ataacgtctt tttgagtatt ttgctctgaa aagctaactc gaatagcttc tgtgagacga
    38221 tgggactgct tgccgaaata agctgccaaa acgtgacttg gctcaacagc accagctgta
    38281 caagcagagc ctgacgacac agcaaagcct gctaaatcaa gctgagtcag taatacatga
    38341 ttttggtaac caggaaagcc gatattaatg atatagggaa gatgacactc attatgattg
    38401 agctgataag aaataccttc taattcacta agcaagagct gtgatagctc tttagcatgc
    38461 tggtaatgct gtggcagcct tgagacagcc tcatctaatg cttgggtcat gccgacgata
    38521 ttaatcaggc tttcagtgcc ggctctttgt ttgttttctt gattgccgcc atgtaagagg
    38581 ggggccaact ttaagccttt attgtataaa aaaccagtcc cctttggtcc atgaaactta
    38641 tgggcagagg cagagagcaa atcaatcccc aaatctgccg gctgtattgg gaccttgcca
    38701 atagcttgga cagcatcaac atgaaagaca gcctgatgct gctttagcat gctaccaaca
    38761 gcctgaatag gcagcaaatc tcccgtttcg ttgttagcaa acatcatgct gactaagatt
    38821 gtatcctctc ttaaggcagc ttggagctga tttagatcaa tgattccatt tttagcctca
    38881 aggtaggtca cctcaaagcc aaatcgttct tccagatagg ccattgtgct taacacggaa
    38941 tgatgctcaa tagcagttgt aatcaagtgt ttgccttttt cctgatgagc taaggcatag
    39001 cccttgatag cagtattgtt actttcagta cctcctgagg taaagataat gtggttttct
    39061 gcagctccta ggcagttggc aatagctttt cggcactctc ttaattgttt gtttgcctgc
    39121 cgcccataag catgaatact agatgggtta ccaaaatcat cagccatagc ttcagtcatc
    39181 gccttgatag cagcctgact aagcgatgtt gtagcagcat tatcaaaata aatcatgatt
    39241 agttagtgct ttcaggtttg taagaaaaca gtggacttag tggttttctt tcgtgaatgc
    39301 gaatgatagc ctctgcaatt aaatcactgg cactaagata ggttactgtt ttagggatac
    39361 gatttttagt cttgacagag tccgtgacaa tgatctcttt gattggagca gtctctaaaa
    39421 tatcagctgc acctcctgca aaaatcccat gactagccac tgcataaatg tcagttgcgc
    39481 ctgcacattc taggatctta gctgcctctg caaaggtttt tcctgtgttg agaatgtcat
    39541 caatcaagat agccttcttg ccagcaacat caccaatcac atagccttct tcgcgctcag
    39601 catcgtcttg tgcataatcg ataatggcaa ttggagagtt aagatactct gctaagcttc
    39661 tagcacgctt gataccagaa tttttagggc tgacaataac cgtatcaggt cctgagaggc
    39721 ccagtggata atagtgcttt gcaaaaagag gcactgtaaa taaattatca actggaatgt
    39781 caaaaaagcc ttggacctga accgcatgca aatcaagggt tacaacgcga tcaatccctg
    39841 ctttggtcag catgtttgcg accagctttg ctgtaatagg ctcgcgagac tttgcaacac
    39901 gatcctgacg cgaataacca aaatatggca aaacaatatt gactgtatta gcacttgcac
    39961 gcttacaagc atcaatcatg atgagcagct cccataggtt atcgttgaca ggaaagcttg
    40021 ttgattgaat gatataaata tcatcaccac gaactgtttc ttcaatgtta atcatgatct
    40081 caccatcaga aaattgacga gatgagacct ttccaagcgg aataccagca gccttagaaa
    40141 ttttttcagc gattgcgaga tttgaagtga gtgagaacag cttgatttgc ttgtcagcat
    40201 atcgttcagt catgataaaa ttagctcctt acattacatt aacgatagaa taacaggtta
    40261 acagttattc aagattacaa atagacagta ctattttaac aaaaaaacag aaaaatttca
    40321 gtctttctgt tgattttctg tcctctccta ggatttttta agggtcttgc taaagcgagc
    40381 gaccttgctt ttggaatatt taaaggtgat ctgatgctgg gctaaaaagt ggtcaaaatc
    40441 aacctttcct cttacaggat cagtcacctc tagctcaagc tcatagtctt tgataccagc
    40501 atattgatta taatccagcg ctagcttgcc aataggagta tctgcctctc gacgaatggt
    40561 agtcaggttt ccgaaggttt ttatagcaga taggtcaacg tcaagagtgc tgataatatc
    40621 aaggatagct gattttggta gctgtcctgt ctgaatgata gcttttgctt gggtgtcatc
    40681 aagctctaaa ttgtactcgc gattaccaac cttttcaggg acttttaagg ttaattcagc
    40741 aggagcagca acaaaggtgc gaatgcgaag tgacatttta tgagccttga gatcaaaatg
    40801 atcagtatca atgtaataat ttgtctgggt aactggtggg acatgagtca tttgagagag
    40861 gaggcgatta tattcgtcct ttgtcagtaa ggtcttgtat tcgatttcta ggttagtcat
    40921 gcgaacgttc cttttaacta tattttatgc tataataaat tgttatctta attttatatt
    40981 aatatccgag gtttgacaag aaaggagaga aaggatggct ttagattggg aagaattttt
    41041 ggatccttat atacaaacgg ttggcgaatt gaaaattaag ctgcgcggta tccgaaagca
    41101 gtttcgcaag caaaaccgtt attctcctat tgagtttgtg actggacgtg tcaagtcggt
    41161 tgagagcatc aaggaaaaaa tggccttgcg tggtgtcttg gaagaaaata tcgctcaaga
    41221 tattcaagac atcgctgggc ttaggattat ggtgcagttt gtggacgata ttgaggacgt
    41281 tttgtccttg cttagacaaa gacaggacat gacaattgtt tatgagcgag actacattag
    41341 aaacatgaaa tctagtggtt atcgctcgta tcatgttgtc gttgagtatc ctgttgatac
    41401 cattgagggt caaaaaaaag tattagcaga aattcaaatc cgtactttag caatgaattt
    41461 ttgggcaacc attgagcatt ccttgaacta caagtacggt ggtgattttc cagaagaaat
    41521 aaaaaaacga ttagaggtta cagcaaaaat tgctttggag cttgatgaag aaatgcgaaa
    41581 aattcgtgaa gacattcgtg aagcacaatt gttatttgat cctgtaacac gtcatttgag
    41641 tgatggtgta ggaaatagtg atgacacaga tgaattatac agataaagta aagcgcgttg
    41701 ctatcattgc aaacggcaaa tatcagagta agcgccttgc ctcaaagctt tttggcgtct
    41761 ttaaggacga tccgagtttt tacctatcca aaaaaaatcc ggatattgtg atttcaattg
    41821 gcggagatgg catgcttcta tcagcctttc atatgtacga aaaagaatta gacagggtgc
    41881 gatttgtagg cattcacact ggacaccttg gtttttacac tgattatcgt gattttgagg
    41941 ttgatcaatt gatagccaat cttagaagag acaccggtga gcaaatttct taccctattt
    42001 taaaggtagt tattacgctt gatgacggtc gcctgtttaa ggctagggct ctcaatgaag
    42061 caactattaa gcgtatcgag aaaacgatgg ttgcagatat tatcattaac aatgtcaagt
    42121 ttgaaagctt tcgtggtgat ggcatctctg tatccacacc aactggaagc acagcctata
    42181 acaaatcctt aggtggagct gtattgcacc caacgattga ggcccttcag ctaacagaaa
    42241 tctcgagcct gaacaatcgt gtatttagaa ccttggggtc ctcagtgatt attcctaaaa
    42301 aagataaaat tgagcttgtt ccaaaaagac taggcgttta tactgtctct gttgacaata
    42361 aaacctacca cttaaaaaat gtggttaagg tggaatattt tatcggcaat gaaaagattc
    42421 attttgtgtc ctcacctagc cacaccagct tttgggaaag ggttaaggac gcttttattg
    42481 gggatagtga atcatgaggt ttgaatttgt tgcaactaaa aaaacaaagg taaagaccct
    42541 tttaaaagag cacgatgtgt caaagggatt gctcgctaag attaaataca agggtggcaa
    42601 tatatgggta aatggcgttg cgcaaaatgc catttattta ttggatattg gtgatgtggt
    42661 ggctattgat attccaaatg aggagtcctt tgagcaattg acagcgattt cgcatgacct
    42721 tgatattgtg tatgaggacg aacattttct cattctcaac aagcctgctg gctacgctag
    42781 cattccaagt gctatccatt ctaatactat agctaatttt atcaaggctt attatatcaa
    42841 gcaggactat cccaataaac aggttcatat tgtgacgcgc ttagatcggg ataccagtgg
    42901 cttaatgctc tttgccaagc atggctatgc ccatgccaga ttagataagc agctacagca
    42961 aagagctatc aataaacgct attatgctct tgtttgtggt caggagaggc ttccagatca
    43021 aggtgagatt atagctccta ttggccgtac ggacgacagc attatcacaa gaactgtcac
    43081 gccaaaggga aagtatgcta agacaagcta caaggtcatt gcccgctatc ctgaaaatgt
    43141 ctctctagtg gatattacgc tgcacactgg tcggacccat caaattaggg tacattttgc
    43201 tcatcttggt tttccacttt tgggagatga tctgtatggt ggtcgattgg accttggcat
    43261 gactagacag gcgctgcatt gtcaccatct tagctttacg cacccattta cagaaagtag
    43321 aagcgatcat acaatatgct tgacagatga ctttgagagc gttatcatag atttacagaa
    43381 aaaagataga ggttagttaa tgagtattcg taatttattt ggtggtttaa gggaaaaaat
    43441 tgtcggcaaa aacatgaaga ttgttttccc tgagggaaat gatgagcgtg ttgtacgtgc
    43501 agcagcacgt ctaaagtttg aaggtcttgt tgagccaatt attcttggtc aggcagatga
    43561 tattcgcagc ctgctaacac agctaggctt tgctgagcag cactatacaa tcattaaccc
    43621 aaatgattat gctgattttg agaaaatgaa agcagccttt gtagagcttc gtaaggtcaa
    43681 ggcaacgctt gaagatgctg atagactgct tagagatgtc aattactttg gtgttatgct
    43741 ggttaagcta ggcttagcag atggcatggt ttcaggggct attcattcaa cagctgatac
    43801 ggtgcgtccg gcgcttcaga ttatcaagac aaagccaggc atttctagaa catcaggtgt
    43861 ctttttgatg aatcgcgaaa atacagagca gcgtttagtg tttgctgatt gtgccattaa
    43921 tattgaccca actgctcagg agctcgcaga aattgcggta aacacagcag atactgcgaa
    43981 aatttttgat attgatccta aggttgccat gcttagcttt tcaacaatgg gctctgctaa
    44041 agccccacag gttgaaaagg ttcaagaggc cgtccgtatt gctaaggaat tgaggccaga
    44101 gcttgcttta gacggtgagc ttcaatttga cgcagccttt gtaccaagta cagcagcgat
    44161 caaagcccct gattcatcag tggcaggcca tgcgaatgtt tttgtcttcc cagatttaca
    44221 gtctggaaat attggctata agattgctca gcgcttaggc atgtttgatg ctatcggacc
    44281 aatcctgcaa ggattgaaca agcctgttaa tgatttatca cgtggctcta gtgcagagga
    44341 tatttacaag ctagctatta ttacagcagc gcaagcgctt gaaaatgagt ctatcaatta
    44401 actgctaata gccattaagt tcacaaggct tagctatagt agatgttgct taaaacgagt
    44461 tggataagcc agctcgtttt ttcagaaagt gaggaaggaa atgacaaaga ttgcattagt
    44521 aacaggcgcc tctgctggct ttggtaaagc cattgcagag cagttaatag cccaaaacat
    44581 caaggtgatc ggagcagccc gccgcataga aaagctaaga gagctagaag gtatttttgg
    44641 ttctgagagg ttttatccgc ttcaaatgga cgtttcagaa ccaactgcca ttgataaagc
    44701 acttgcagaa ttacctaaag aatggcaggc cattgatatt ttagttaata atgcaggact
    44761 agccttagga cttgataagg cctatgaggc tgatgtcgcc aactggctaa ccatgattaa
    44821 tactaatatt attgggctta tctatttaac acgtcaggta ttaccgcaaa tggtaagcag
    44881 caacaatggc atgatcatca atatcggctc aactgctggc actattccct atccgggagc
    44941 taatgtttat ggggcttcaa aagcctttgt taagcagttt tcgcttaatt taagggcaga
    45001 tttagcagga acaaatatca gggtgaccaa tattgagcct ggcctttgtg agggaacaga
    45061 gttttctcat gttcgcttta agggtgacca tgagcgtgtt aaagcacttt atgcaggtgc
    45121 acatgctatt cagccaaggg atatcgcaaa tactgtctca tggattattg atcagccaga
    45181 gcatgttaac attaaccgcg tggaaatgat gcctgtctca caaagctatg gttctcagcc
    45241 tgttagccgt catgactaag aattacaaga gcagatgtaa aaggattgtc gaagtgcaac
    45301 ccaaaaagac ttaaagccta gctgttttat agcctggctt taagtctttt tctctaattt
    45361 ttcttagaaa tgatccgaaa gagaaggtcc agatgtgaca tctgaccacc caacaatggc
    45421 ctgccctgtt tcttccaaat agtgctgcag cataggcttg aagtccaaaa tcatgtcata
    45481 gaccccaaca aattgcttgg tatcatcgta caaggcttga tattgctgca tataaatatg
    45541 atcctgtgaa gcagtcggaa taagatacag cttactgcca gttgccgcct tgtgcaaatc
    45601 agtcaagatc caatcctcaa tgacatcatg cttatcagaa gcaaaaaaat tgccattaaa
    45661 gcgatgatta tcaaagatga tctgcccctg atgatcagca attctagcct gaaggggaag
    45721 ataggttaaa aaatgtgggg ctaaggcttg gtaaaattgc atgaggtatt tagcaagtct
    45781 taaagtttgc tgactatcag taaaggtatg atcactaacg gtaaatcctt gctctttgtc
    45841 tgcctgatta aaataaagta caggtagtga ggcttcaagg ttctgaaagg taaaaatggc
    45901 ctgagccttt ttgagctgct cagtagtcag ctgacggaca atagtgatat gaaacagata
    45961 gctaaactct tgtgataagg tggtaaaaaa agtcttttgc agattattct tatcatcaac
    46021 cagtgctaag gtataaatcg ttttagtcat aaggctatca tagctttatt ttgtttaaat
    46081 agcaatgaaa cagcctttta gtctacagac ttagttgata gcttaataaa agaaagcaat
    46141 atgaaaaaat gattaaagca aactagttga cttgttagtt taaacttttt ataataaatc
    46201 aaatgagaag ataatatgag gcttagccta agctgctgag cttatctgat aatcattctt
    46261 cttagcactg agataacccc ctttatcgat taattggaga atctatgata cgttttaata
    46321 atgtttccaa aacctttggt cacaccaagg tgctgcagga gcaaagtttt caaatacaga
    46381 atcgcgaatt ttttgtgctg gtcggtccaa gcggctctgg caaaacaaag ctcttaaaaa
    46441 tgatcaattg ccttactgaa ccaagctctg gcgaaattct attaaacgga aggccacaaa
    46501 aagagctaga tttgcgagat atgcgcttat ctattggcta tgttcttcag caaattgccc
    46561 tgtttccaaa ccttacagtt gctgaaaata tcgctattat tccagagatg aagaagtggt
    46621 cagacaaaga gattagaact aagacagagg aattgttaga taaggttgga ttgcctgcaa
    46681 gggattatct aaatcgctat cccagtgatt tatccggtgg agagcagcag aggattggta
    46741 ttgttcgtgc catcatttct caccccaagg tgctgttaat ggacgagccg ttttcagcct
    46801 tggatcctat ttcacgcaag taattacagg acttgatgtt aagtcttcac aaggagtttg
    46861 atatgacaat tgtctttgtt actcatgata ttgatgaggc tatcaagctt ggagatcgtg
    46921 tggctgtttt aaatgaaggg caaattgttc aactggatcg accagatgcg atcatagctg
    46981 cgcctgctaa tgattttgta gcaagtctat ttggaggtcg tgattatgcc tagtttactg
    47041 atgacctttt gggatcgttt tggtgattgg gcaagggcat taggagagca cttgcagatt
    47101 tctcttcttt ctttgctggc tgccttgctg ataggcattc cgcttgcagc tctgttgagt
    47161 aaaagtaagc gctggtcaaa tatcatcttg cagctgacag gtgtttttca aaccattcct
    47221 tccctagcct tgttgggact atttatccct ctaatgggaa tcggaactgc tccagctgta
    47281 acagctttgg ttatttatgc catatttcct attttacaaa atacgattac tggcttaaat
    47341 gctattgatc caagtcttgt agaggccgga acagcctttg gaatgaccaa gtgggagcga
    47401 ctgaaaatat ttgaaattcc tattgctatg ccagttatta tgtcaggtgt tcggacctca
    47461 gcagtgatga ttattggaac agccacccta gcttctttga tcggagctgg cggcttaggg
    47521 acctttatcc tattaggaat tgaccgtaat aatgctcagc tgattgtgat tggtgctgtg
    47581 tcgtcagcct tgcttgcgat agtgtttaac agtcttttgt gataccttga gaaggcctca
    47641 ctgaggcgta ttgcgataag ctttgctgcg accttattac tgctcttaat ttcctatact
    47701 ccaatgtttg tcaagcggtt tgttaatcag tcaaatactc tggtgattgc tggcaagcta
    47761 ggagtagagc cggatatttt gatcaatatc tataaagagc tgattgaaga ccagtccaag
    47821 cttaaggttg aattgaaacc taattttggc aagacaagct ttttatacga ggcgattaaa
    47881 tcaggagata ttgatattta tccagaattt acaggaacca tcacctctag cctattaaag
    47941 aaaaagccta agctttctaa tgaccctaat caggtttact tagctgctaa ggaggggatt
    48001 gctgagcagg atcagttgac gcttttaaag ccctttgcct atcaaaatac ctatgcagtg
    48061 gcgatgcctg aaaaaatagc tgacgaattt aacattcaaa gtatttcaga tgtgaagaaa
    48121 tatgaaaaac agctaaaggc tggttttaca ctagaattta aggatagaga ggacggctat
    48181 aagggcatac aggataagta tgatctacat ttatcagttg caacgatgga gccagctctt
    48241 aggtaccaag ccattcagtc aggaaacatt cagctgacag acgcttattc aactgatgct
    48301 gagatcgtga aatatcagct tcgagtctta aaggacgata agcagctctt tccaccttat
    48361 caaggagcgc cattgatgaa ggcttcctta ctaagaaagc accctcatct caaaacgatt
    48421 ctcaatcagt tatcaggaaa gattactgaa gaggagatgc aagcaatgaa ctatgaggtg
    48481 tccgtaaagg gcagagcagc tagccttgtg gcacatgact accttgtaaa ggccggtctt
    48541 attgcaagaa ccaaataagc aggcatgcta gtcttattct ggactggcat gctttattta
    48601 tgtgattttt agtctgtctg gctctgcaag gtgtgtgcca aataaccgct cgtttgatgt
    48661 gtggttattg atttagtagc taaggattgg aatcttaaaa taaaatccga acgtttgtct
    48721 aaaaaaagct ttaaaaattg acaaaacata aacgaaagga taaaataaat taaggaaagg
    48781 taacatttta cctagcgatg cctcggacaa gcttgaggtc ataggaaggt cattttatat
    48841 agaagcttat gtcagctgca gatcagggaa gtccttgctg gattagtagc tgaatgttga
    48901 aaaaggagag aaatgatgtt taatgacatg cctgtatttg attatgagga tattcaatta
    48961 attcctaaca aatgtatcat caatagtcgt tcagaagcag atacgagtgt aagacttggt
    49021 aattatacct ttaagctacc tgttattccc gccaacatgc aaaccattat tgacgaaaca
    49081 attgcagagc agttggcaag agatggttat ttctatatta tgcaccgctt tgatgaggag
    49141 gggcgcaagc cctttatcca gcgtatgcat gagcaacagc tcatcgcctc tatttcggtt
    49201 ggtgtaaagg attatgaata cgatttcgtc tcttctttga aggaggacgc acctgagttt
    49261 atcacgattg atattgctca tggccatgct gatagtgtga tcaaaatgat taagcatatt
    49321 aaggctgagc tgcctgagac ctttgttata gctggaaatg tcggaacacc agaggctgtt
    49381 cgagagctcg aaaatgctgg tgctgacgca acaaaggtcg ggattgggcc tggtaaggtt
    49441 tgtatcacaa aggttaagac aggctttgga acaggggggt ggcaattagc tgctgtacgt
    49501 tggtgtgcta aggctgctcg taagccgatt attgctgatg gcggtattcg tactcatggt
    49561 gatattgcca agtcgattcg atttggggca acaatggtga tgatcggttc actctttgca
    49621 ggtcatattg aaagcccagg caagatggta gaaatcgacg gacagtcctt caaggaatat
    49681 tatggctctg cctctgaata tcaaaaaggg gagcataaaa atgtcgaagg caagaagatt
    49741 ttgcttccaa ccaagggtca tctagctgat actttaaccg aaatgaagca ggatttacag
    49801 tcatcaatct catatgctgg aggcagagat ttggagagcc tgcgtcgtgt gaattatgtt
    49861 atcgtgaaaa attctatttg gaatggtgac tctatttaaa gccttggcta aagacctagt
    49921 ctaaataagg ataagcaagc tgattgatgc tgagaataag cacagcgtgt ctataggacg
    49981 cctgaatgtc tagtagccag taaagctttt aggcttgctg attggatagg tcattgtgcc
    50041 tatgtgcagc agggctctag ggacttagat aaaaaggaga catgatgagg ttactggagg
    50101 agcgtatcct agctgatgga actgttttag gtgagacgat tttgaaggtg gatcaatttt
    50161 taacacatca ggttgactat cgcttgatga aggaaatcgg tagagtattt gctgatcaat
    50221 atgctgattt gggcattacc aaggtggtca ccattgaagc ctctggtatc gcaccagcag
    50281 tttataccgc agaagctctt gaggttccga tgatttttgc caaaaagcac aaaaatatca
    50341 cgatgacaga gggaatttta acagcagagg tttattcctt taccaaacaa gtgacaagta
    50401 ctgtttctat tgcaggagga ctgctatcaa aagaagatag ggttttgatt attgatgact
    50461 ttttggctaa tggtcaagcg gcaaaaggct tgattgatat cattcatcaa gcaggggcca
    50521 aagctgttgg cataggcatt gtcattgaaa aatcttttca ggctggacgg caattgcttg
    50581 aggatttggg agtagaggtc acttcattgg ctcgtattaa gcattttgac aatggaatag
    50641 taagcttttt ggaggctgat gcctgatgac tgcttcttat ctctcagcat taagcttttt
    50701 acttgtatag ctataccagc tttatttcag tagctattgg ctggtgataa gggatattgg
    50761 tatggcggtg cattacggcg agccgtgggc agttgccctt gcggctttac gatttagtat
    50821 agactatcaa gaattgactg cttccttttt atcgagatga atcattagac agacaatcat
    50881 gatttggcgt gaaggctgct ttcagtaaac attacatcat caaaaatcag ctaggtattc
    50941 acttagctga tttttagtgc ttataatgta gccgaaaggc tccctttaac ccgtctgaga
    51001 tagtaacctg accatctttg gtaatgataa tgccttccac ctcaggcagc ttatttagct
    51061 gacttaggac aaaggaatgc tctaagccaa aaagacgact actccatagc tcaccatcaa
    51121 gtgagaattg gctgacaatg gttaggctag ccatattggt cttgatagga tagccgttgt
    51181 gaggatcaag aaggtgatga taagttttgt ctttgatttg taattgtctc tcgccgattc
    51241 ctgaggttac tacagattta ttgttaacct taatcacgcc gacatgctgt cctctttttt
    51301 gattggtctg ctggatccca acgtaaaaca agccattatg tcgttgcttg ttggtgccat
    51361 gcacaaggac atttccacct agattgataa gagcagcagt gataccgtct ttaataagaa
    51421 atgccatgag cttatcagca atatagccct ttgctagggc acctaagtcg atagacatgc
    51481 ccttttcttt caaaaaaata cttccaaggc tttgatcta
//
LOCUS       DARYNN010000008        50820 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.008, whole genome shotgun sequence.
ACCESSION   DARYNN010000008 DARYNN010000000
VERSION     DARYNN010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 50820)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50820)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50820
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.008"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            160..384
                     /locus_tag="TVB59_000409"
     CDS             160..384
                     /locus_tag="TVB59_000409"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009349.1"
                     /translation="MNYSRPCIKDIYPIYKLSDTMFRIGAQINITTEFNDSNYETGAS
                     FTHKLWPHFKECPACGHGNSNDWEIFSHYG"
     gene            395..1315
                     /locus_tag="TVB59_000410"
     CDS             395..1315
                     /locus_tag="TVB59_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1009350.1"
                     /translation="MEQYELMVRSLSKRYARDGSYANRDLHCVFKSSEITALIGHNGA
                     GKTTLLNQIIGNIKPDVGDISFLDCSFVKSPKIARKNTSMMPQLHAPLKGITIKQAIS
                     SIGKIRGLSGKLLETEVQELIQELGLIKWQNTIGEKLSGGLKRLTSFAMAVIAAPKIV
                     LLDEPTNDVDPIRRIKLWLYLKKMAAKGHIVIVVTHNILEVEKYADAYYLLEKGEVKS
                     SGAVKTLSSNPKSRISILFRDQKALEEYPFAYSLGGDDNEAITIMDNKEMTALLNWLG
                     IHLSSDTIVQYSITTLGLNDYYEELSDEED"
     gene            1302..2042
                     /locus_tag="TVB59_000411"
     CDS             1302..2042
                     /locus_tag="TVB59_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1009351.1"
                     /translation="MKKISVTYQFLSLLNWSFIRHKSLILLCSVIQFFMTIALVYGYS
                     LIIADDTVQTVYYLASGSVTIGMITIGCTVSAQSISSDKRDGIVSYIQTLPVLRSLIL
                     LSDLLIWTLTALIGVGVSIAVVYLKFQILPQLSLATFLILPLVLMTMISMGFAIAYWS
                     TPSTMMLVTQLLLMIGLLFSPIMYPAERIPEVILRGYHFLPFIPAGDLIRETVYLGHS
                     ISVVKLVVLLLWLVATALLSVNWLNRQS"
     gene            2199..3947
                     /gene="aspS"
                     /locus_tag="TVB59_000412"
     CDS             2199..3947
                     /gene="aspS"
                     /locus_tag="TVB59_000412"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEL1009352.1"
                     /translation="MKRSMYAGHVRKEHIGRTIVLKGWVSRRRDLGGLIFIDLRDREG
                     VMQLVINPEDVSGDVMATAERLRSEYVIEVEGSVEARQQANDKLATGAVELKVSGLTI
                     LNTAKTTPFEIKDGVEVSDDTRLRYRYLDLRRPEMLESFKLRAKTTHVIRNYLDNLGF
                     IDVETPMLTKSTPEGARDYLVPSRISQGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLSEQEIQDIVEGMIAKVMKDTKGIEVKLPFPRMAY
                     DDAMNHYGSDKPDTRFDMLLQDLTDLVKEIDFKVFSEAQAVKAIVVKGHADRYSRKDI
                     DKLTEFAKQFGAKGLAWLKVVDGAFTGPIAKFLTGVKSKLTESLQLEHNDLVLFVADT
                     LEVANNTLGALRTRIAKELDMIDMSQFNFLWVVDWPMFEWSEEEERYMSAHHPFTLPT
                     AESAHELEGDLAKVRAVAYDIVLNGYELGGGSLRINQKDMQERMFRALGFTAEEANEQ
                     FGFLLEAMEYGFPPHGGLAIGLDRLVMLLAGKDNIREVIAFPKNNKASDPMTQAPSLV
                     SEKQLEELQLQIEHHD"
     gene            3940..4887
                     /locus_tag="TVB59_000413"
     CDS             3940..4887
                     /locus_tag="TVB59_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEL1009353.1"
                     /translation="MIKKTTYRKRVKYLINRGAKKIGLLHAVKSISKEKYTEKISASL
                     LYGILSSIAVNFFFQPGHVYSSGATGLAQVISAISHHLWGFEIPVALAFYVTNIPLLV
                     LAWYKIGHKFTIFTFITVSMSSFFIQIMPQVTLTTDPLINAIFGGLVMGLGIGTGFKS
                     RISSGGTDIISLTLRKKTGKDVGNLSLMINGVIMAFAGLLFGWQYALYSMVTIFVSSR
                     VTDAIFTKQKKMQATIVTSCPDKVIHMIHKKLHRGVTSINDAEGTYKHEHKAVLITIL
                     TREEYSEFKWLMLKTDPNAFVSVAENVRIIGRFVESDED"
     gene            4903..5784
                     /locus_tag="TVB59_000414"
     CDS             4903..5784
                     /locus_tag="TVB59_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEL1009354.1"
                     /translation="MPANKSLKLKNCCFIILGSAIYAFAFVYFYMANRIAANGLAGLT
                     QVANALFQINPSITGYLINLPLVLLGARLFGRRAMVYTVTGILSLYWFVWLFQQLPLF
                     IDLDHDNLVVSLLAGILGGLGGGIVFRNGGTIGGSDIIAKLIEDRFGLQLNQALLGID
                     IFVIVVSLTYISIPQMMYALIASFMYSRIVHLVQNGGYSARGTFIISDYSQTISQFIM
                     EELGRGVTYLHGEGAYSGREKQVIYVALGRSDVRELKAFIAQVDPNAFVSFFDVNEVN
                     SPEFIATKSKYHKTKKR"
     gene            5928..6842
                     /locus_tag="TVB59_000415"
     CDS             5928..6842
                     /locus_tag="TVB59_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEL1009355.1"
                     /translation="MTNLDKWHRVRELLLIAVGVAIYTFGFVNFNMANELAEGGVAGI
                     TLILHAHFGINPAYSSLLFNLPLFMLGAKIFGRRSLALTIYGTVLMSVFIWLWQKVPM
                     ELGLENDMMLVAVVAGLFAGIGSGLVFRYGATTGGTDIIARIAEEKFGAKLGQTLLFV
                     DALVLTASLTYVDLKHMLYTLVASFVFSQMISVVQNGGYTIRGMIIITKQSQAAAQAI
                     LTEINRGVTYLKGQGAYSGHDYNIMYVTLNPTEVREVKRILAELDPDAFISIIDVDEV
                     ISSDFKIRRKNFDKPIEKALQKKSNMLK"
     gene            7014..8408
                     /locus_tag="TVB59_000416"
     CDS             7014..8408
                     /locus_tag="TVB59_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEL1009356.1"
                     /translation="MEALSIQHYALDTAEKNLLTIDSLTLNQGERVFIIGDNGAGKTS
                     FLKTIIGESTNYSGFLQVHGDIAYVPQIKSTSPQSGGERAMSYLKEAFQARPSLLILD
                     EPSSYLDHANRDWLINQLKRYRGTLLVVSHDRYLINQLSQKIWLLEHQTIKTYHGNYD
                     DYQRSRQLEEDKQLRAFLEYQRKTNQLKKSLTRKKVQANKMAVKKKSVSRSDWKTNSF
                     AGSYDSQAKAMAKAAKAMENRLTRMKEVNSPRKKAWAKLKKDPNEGALPNTLLHLQEG
                     TLTRDHQLLFDYPGIVIRSHSRIAIIGRNKAGKSSFLDQLAAQALSGFYAQNLRITYF
                     KQDQADLEPDQTAVELISRQSSQDRVTILNYLAMMGIDYDKANQKVAVLSGGERVRLA
                     LVAALLTDHQLLILDEPTIYLDLVAIEALESCLIDYPAALLLVSHDLAFVNKVATEIY
                     EVKDHHLTAYHFED"
     gene            complement(8456..10147)
                     /locus_tag="TVB59_000417"
     CDS             complement(8456..10147)
                     /locus_tag="TVB59_000417"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEL1009357.1"
                     /translation="MDTKTLIAAEIAKIVPELEQAAIFNLLETPKNSDMGDLAFPAFS
                     LAKALRKAPQAIASDLAERIDASQFEKVAAVGPYVNFFLDKASISAQVLTQVIADGAD
                     YAQQDEGQGRHIAIDMSSPNIAKPFSIGHLRSTVIGDSLAHIFAKMGYKPVKINHLGD
                     WGKQFGMLIVAYKKWGNEAAVQAHPIDELLKLYVRINAEAETDPSLDEEAREWFRRLE
                     ERDQEATELWQWFRDESLIEFNRLYDQLGVSFDSYNGEAFYNDKMDEVLELLEDKGLL
                     VESKGAKVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKRTYDFAKSVYVVGNE
                     QAAHFKQLKAVLKEMGYDWSDDMTHVAFGLVTKGGAKLSTRKGNVILLEPTVAEAISR
                     AANQIEAKNPKLANKEAVAHAVGVGAIKFYDLKTDRMNGYDFDLEAMVSFEGETGPYV
                     QYAHARIQSILRKASFTPATDTSYSLNDPESWEIIKLIQDFPRIIKRAFDNFEPSIMA
                     KFAIHLAQSFNKYYAHTRILEDDPERDNRLALCYATAIVLKEALRLLGVEAPNEM"
     gene            10424..10861
                     /gene="argR"
                     /locus_tag="TVB59_000418"
     CDS             10424..10861
                     /gene="argR"
                     /locus_tag="TVB59_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEL1009358.1"
                     /translation="MNKIERQQQIKQLIQAEHIGTQEEIRRLLQKDGIVVTQATLSRD
                     LREIGLLKLRDDRGKLYYSLSEPVATPFSPDVRFYVLKVDRAGFMLVLHTNLGEADVL
                     ANLIDNDAIEDVLGTIAGADTLLVICRDEEIAKRFEKDLAAGL"
     gene            10863..11213
                     /locus_tag="TVB59_000419"
     CDS             10863..11213
                     /locus_tag="TVB59_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HEL1009359.1"
                     /translation="MPYRESLHQLIAALEKHSSIIAYKEAQQHLLQRTDYNQKAYQMK
                     RHQQDTYLFRQIAKDKAAEESAFKAQQLREDLDHQPLIDDYRDKMQNASDLVRYITGT
                     IEDELNKEFNDGKG"
     gene            11200..13755
                     /gene="mutS"
                     /locus_tag="TVB59_000420"
     CDS             11200..13755
                     /gene="mutS"
                     /locus_tag="TVB59_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEL1009360.1"
                     /translation="MAKANVSPGMQQYLDIKKDYPDAFLLFRMGDFYELFYEDAVKAA
                     QILEIGLTSRNKNADNPIPMAGVPYHSVQQYIDVLIDLGHKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTAVDSSRPDSPNNFLVAVDFDGKAYGLSYMDVSTGEFFATDLADFAS
                     VKSEIQNLKAKEVLLGFELSEEEQAILVKQLNLLLSFEMTALEDSPLIDHQLTAVELS
                     AAGKLLHYVHQTQLRELSHLQALVHYDIKDYLQMSYATKSSLDLLENARTGKKHGSLY
                     WLLDETKTAMGMRLLRAWIDRPLVTSEAILERQEIIQVFLNAFIERTDLSDSLKGVYD
                     IERLSSRVSFGKANPKDLLQLGHTLAKVPYIKAILEAFNSPYLDKLVNQIDTLPELEH
                     LIRSAIDPDAPATINEGNIIRTGFDERLDHYRKVMREGTGWIADIETKERQASGISNL
                     KIDYNKKDGYYFHVTNSNLGMVPDHFFRKATLKNSERYGTAELAKIEGQMLEAREESS
                     SLEYDIFMRIRAQVETYIDRLQQLAKALATVDVLQSLAVVAEKNHYVRPLFNQESKIA
                     IDNGRHAVVEKVLGVQEYIPNSISFGPQTSIQLITGPNMSGKSTYMRQLALTVIMAQI
                     GSFVAAESASLPLFDAIFTRIGAADDLISGQSTFMVEMMEANHAIKRATPHSLILFDE
                     LGRGTATYDGMALAQSIIEYIHDRVGAKTMFATHYHELTELSTKLTKLVNVHVATLEK
                     DGNVTFLHKIAEGPADKSYGIHVARIAGLPEDLLARADTVLTKLEAQSQARESVLSTT
                     EVRETQQLANQQLSLFTDDGSSSEIIKRLESVDVMNLTPIQAMTVLYELKKLL"
     gene            13902..15884
                     /gene="mutL"
                     /locus_tag="TVB59_000421"
     CDS             13902..15884
                     /gene="mutL"
                     /locus_tag="TVB59_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEL1009361.1"
                     /translation="MTTIIELPEVLANQIAAGEVIERPASVVKELVENAIDAKSSQIT
                     VEIEESGLKMIQITDNGEGMSHEDLPLSLRRHATSKIKSQSDLFRIRTLGFRGEALPS
                     VASISKLTIKTATADAEHGSILVASGGKIEQLEAVSTPVGTKIKVENLFYNTPARLKY
                     MKSLQAELAHVVDVVNRLSLAHPEIAFTLISDGKQLTQTSGAGDLRQALAGIYGLNTA
                     KKMIDISSADLDFEVGGFVSLPELTRANRNYITILINGRYIKNFLLNRAILDGYGSKL
                     MVGRFPIAVIDIQIDPYLADVNVHPTKQEIRISKERELMALISTAISESLREQDLIPD
                     ALENLARSSTRSFSKPEQTSLPLQPSQLYYDPQKNDFFTKETVVSEDSPQGFNHETLV
                     DSGVKQVDNLQLAKTESEAAAPSVKYASRPDPMLSDGEHPGLDVHNKQKLSQMLDRLE
                     NEEQSVFPELDYFGQMHGTYLFAQGRDGLFIIDQHAAQERVKYEYYRDKIGEVDNSLQ
                     QLLVPYLFEFSGSDFINLQEKMSLLNEVGIYLEPYGNHTFILREHPIWMKEAEIESGV
                     YEMCDMLLLTNEVSIKTYRAELAIMMSCKRSIKANHSLDDYSARQLLLQLAQCKNPYN
                     CPHGRPVLINFSKADMEKMFRRIQENHTSLRELGKY"
     gene            15895..17118
                     /locus_tag="TVB59_000422"
     CDS             15895..17118
                     /locus_tag="TVB59_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1009362.1"
                     /translation="MREFFQLPKQIQIRQFVRFITITLGSSIFPFMAMYYTSYFGAFW
                     TGILMMVTSFTGFIGTLYGGHLSDAIGRKKVIMLGSVASTLGWLLTILANVPKTVLPW
                     LTFVGILLVELASSFYAPAYEAMLIDLTDDSNRRFVYTINYWFINIAIMLGAGISGLF
                     YDRYFLELLIALLIINIVCFGIAYRYFGETRPEHYRFEHGIGILAGFANYRQVFKDRA
                     FVLFTIGTILFSSIWLQMDNYVPVHLKLYFEETDVLGIHLTSSKMLSLMVFTNTLLIV
                     LLMTVINRLTARWRLLPQLVIGSVIFAFGMLLSFTFTGFFAIWCSVVVFTIGEMLNVP
                     ANQVLRAEMMDQSKIGSYTGFVSMAQPLGAILAGLLVSLSHFTGQAGVQLAFVLIACV
                     GLYVIVLSAKMKKKV"
     gene            17120..17716
                     /gene="ruvA"
                     /locus_tag="TVB59_000423"
     CDS             17120..17716
                     /gene="ruvA"
                     /locus_tag="TVB59_000423"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEL1009363.1"
                     /translation="MYDYIKGQLTKITAKYIVVEANGLGYMITVANPYSFTDCVNQQV
                     TIYLHQVIREDAQLLFGFHSEEEKDVFLKLISVSGIGPTTALAIVAVDDNRGLVNAID
                     NSDITYLMRFPKIGKKTAQQMVLDLAGKFVEAPKEESSKPPKAKQQGNEQLDEAVEAL
                     LALGYKATELKKIRAFFEGTSETAEQYIKSALKMLMKG"
     gene            17726..18277
                     /locus_tag="TVB59_000424"
     CDS             17726..18277
                     /locus_tag="TVB59_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEL1009364.1"
                     /translation="MKRCAWVPQDNKLYCDYHDLEWGRPVYDDRALFELLCLESYQSG
                     LSWLTVLKKRPAFRSVFHHYDISAVASFSEQEMAAALQNAAIIRHKPKLIATVNNAAA
                     VQRIQQEYGSFSSYLWNFVGGQPIDRLVNDDNPAPAQTALSLKLSKDLKKRGFKWLGP
                     TTVYSFMQAAGLVNDHEENCEFR"
     gene            complement(18713..19558)
                     /locus_tag="TVB59_000425"
     CDS             complement(18713..19558)
                     /locus_tag="TVB59_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1009365.1"
                     /translation="MRWDYGKIYQAIRKSKGLTQEKICGDFLARSTLARIESGQVIPK
                     FDTMIFLLNQLNMTLEEFRYVCNTYHPSTRQDILNQFYNQVSAVNITELEKLRQKCFN
                     YLKNKNDIPISYILDSVEVMISLRKKGVKNNQDLQELAYKIWNSLVKQDTWYEKDLQL
                     LHTILFHFPIEIIENISQKILDSLAKYKDYRNIKSSEYALLTNLSTIYLYHNLKKECE
                     EITLLTIKLARQLKRYDSLGFSQVRLGICRNDDHLINKGLQLLQLTEETELLETLQHE
                     LKNYR"
     gene            19855..20427
                     /locus_tag="TVB59_000426"
     CDS             19855..20427
                     /locus_tag="TVB59_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase"
                     /protein_id="HEL1009366.1"
                     /translation="MKKRLAFILVAFGILGFSLGNEVLAADTAPASATMATDSDVSFY
                     NGELLKKYLVQSGDRLYFDYDKAIQDKVSDGVIDMGFLVETISEDYSQQTFTSRKYFK
                     AGWQLYGNYCGPGHNGNHFTLPVIDVLDQGCQNHDSCYRWGAGIGANCECNRQLVNYI
                     KVYRRWMPAHALGVADAIRVYFETVGAIGC"
     gene            20421..20711
                     /locus_tag="TVB59_000427"
     CDS             20421..20711
                     /locus_tag="TVB59_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009367.1"
                     /translation="MLTLKNIINRYYMYYVFLIVVIWIGMFFVRWDTTVAGVLLYPLI
                     MKQVFIVLGVVAMIMAIISRKIVLGIFGLLCCAAFWINLFLAFYLLPGLLGN"
     gene            21397..22668
                     /locus_tag="TVB59_000428"
     CDS             21397..22668
                     /locus_tag="TVB59_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEL1009368.1"
                     /translation="MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGD
                     NEERLLSVIDIASQRSDLVILCGGLGPTDDDLTKQTLAKYLGKALVFDEQAGQKLDAF
                     FAHRKQAARTPNNQRQAQLIEGSIALQNQTGLAVGGLITVDRVTYVVLPGPPSELKPM
                     VKNELVPLLSASHASLYSRVLRFFGIGESQLVTALEDLIKHQTDPTIAPYAKTGEVTL
                     RLSTKADNQALADERLNRLEAQLLSIRTVDNQPLRRLLYGYGEDNSLARETFELLKRS
                     GKTITAAESLTAGLFQAQLTDFAGASQVFNGGFITYSIEEKARMLGIPLGELQRHGVV
                     SSFTAEQMAAQARCLTNSDIGIGLTGVAGPEALEGQPAGTVFIGLATKNKVESLKVVI
                     GGRSRLDVRYIAALYAFNMVRKTLLKSENLL"
     gene            22762..23898
                     /gene="recA"
                     /locus_tag="TVB59_000429"
     CDS             22762..23898
                     /gene="recA"
                     /locus_tag="TVB59_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEL1009369.1"
                     /translation="MAKKVKKNEEITKKFGDERRKALDDALKNIEKDFGKGAVMRLGE
                     RAEQKVQVMSSGSLALDIALGAGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDNHVGLQARMMSQAMRKLSASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGTTQIKGTGDQKDSSIGKETKIKVVKNKVAPPFKVAE
                     VEIMYGEGISRTGELIKIASDLDIIQKAGAWFSYNGEKIGQGSENAKRYLADHPELFD
                     EIDHKVRVKFGLLEDTEESAAADTVAAKADELVLELDDAIEIED"
     gene            24274..24672
                     /gene="spx"
                     /locus_tag="TVB59_000430"
     CDS             24274..24672
                     /gene="spx"
                     /locus_tag="TVB59_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEL1009370.1"
                     /translation="MIKIYTISSCTSCKKAKTWLNAHKLPYKEQNLGKEPLSREEILA
                     ILSKTENGVESIVSSKNRYAKALNCDIDELSVNEVIDLIQDNPRILKSPILIDDKRLQ
                     VGYKEDDIRAFLPRSIRNIENAEARLRAAL"
     gene            24785..25054
                     /locus_tag="TVB59_000431"
     CDS             24785..25054
                     /locus_tag="TVB59_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEL1009371.1"
                     /translation="MGFTDETVRFNLDDGDKKQISETLTAVYHSLDEKGYNPINQIVG
                     YVLSGDPAYVPRYNDARNQIRKYERDEIVEELVRYYLQGNGIDIR"
     gene            25051..25470
                     /gene="ruvX"
                     /locus_tag="TVB59_000432"
     CDS             25051..25470
                     /gene="ruvX"
                     /locus_tag="TVB59_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEL1009372.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIRINEDKQDFGFDR
                     LAELVKQYQVDRFVIGLPKNMNNTSGPRVEASKAYGDKIEELFHIPVSYQDERLTTVE
                     AERMLIEQADISRGKRKKVIDKLAAQLILQNYLDCNY"
     gene            25480..25779
                     /locus_tag="TVB59_000433"
     CDS             25480..25779
                     /locus_tag="TVB59_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEL1009373.1"
                     /translation="MTHNHDHEHEVITLVDEQGNEALFEILLTIDGREEFGKNYVLLV
                     PAGSQEDESGEVEIQAYSFTENEDGTEGDLQPIPEDSDAEWDMIEEVFNSFLDEE"
     gene            26327..27886
                     /locus_tag="TVB59_000434"
     CDS             26327..27886
                     /locus_tag="TVB59_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2079 domain-containing protein"
                     /protein_id="HEL1009374.1"
                     /translation="MSQLHQEVMLEKVNYLVKDHPSSHTTKYDMKVPSLYKFYIFFFS
                     IIASLLTVAVPFFADTANSVQSQNLYIGMMLTKGQIPYSDLFTTGGFLFFVLIALSYH
                     LGTTVWLVLVQALCFYLTGVYFYKLIHYVTGIQKVALGFTAIYYLLSISLGFGGLYAI
                     QLALPFVLVSLWFLTKYFAGLVKDEAFILFGFAAAIAMLIEPRTLLFWLLACIAIIAY
                     NVSQKHFARGFYQLLAAIFGMLLVFYTAGYFILNLQILSPYLEQALVYPFSYFVTGDL
                     SLILGLTVQLGLVLGLGLLTGLLTFMKQPKLESDLAMKWLLVFVVFSYAGIAAISHDF
                     HTYHLLPLLPYALILLSSSVGRQYEAGLRMVSHRRRKGKNGARRVIAIYLNKHFYVPA
                     IIMLGAVFGTAYQYVTSSAINQERSQIAHYLRQRLTEDQPIYVWDDTSKIYLETQAKS
                     ASQFASPFVNLKKESHQQMLEDELLQNKAVYIVVNKQKALPKAVKKIVTANYKIDRKI
                     DVKGFSLYQKK"
     gene            27983..30181
                     /gene="nrdD"
                     /locus_tag="TVB59_000435"
     CDS             27983..30181
                     /gene="nrdD"
                     /locus_tag="TVB59_000435"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011529096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEL1009375.1"
                     /translation="MITLEKDKVIVQPAIKVIKRDGRLVNFDATKIYSALLKASMKVT
                     RMSPLVEAKLEAISERVIAEIIERFPTNIKIYEIQNIVEHELLAANEYAIAKEYINYR
                     TQRDFARSQATDINFSIDKLIHKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLKL
                     LPAHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLANGFKIGNAEVESPKSIQT
                     ATAQISQIIANVASSQYGGCTADRIDEFLAPYAELNFKKHMADAEKWVIEELRESYAF
                     EKTKKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSWFEREIQKAILTIRINGL
                     GSEHRTAIFPKLIFTVKRGLNLEPDSPNYDIKTLALECATKRMYPDMLSYDKIIELTG
                     SFKSPMGCRSFLQGWKDEQGQDVTSGRMNLGVVTMNLPRIAMESNGDMDKFWELFNER
                     LHICKDALVYRVERVKEATPANAPILYQYGAFGKRLAKTGNVDELFNNRRATVSLGYI
                     GLYEVATVFYGGQWEHNQEAKDFTITIVKEMKKACETWSDEYGYHFSVYSTPSESLTD
                     RFCRLDTDKFGVVADITDKEYYTNSFHYDVRKNPTPFEKLDFEKAYPAAGASGGFIHY
                     CEYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDKCYECHFEGDFTPTERGFTCPNCG
                     NNDPKTVDVVKRTCGYLGNPQARPMVNGRHKEISARVKHMNGSTIKYPGI"
     gene            30287..30433
                     /locus_tag="TVB59_000436"
     CDS             30287..30433
                     /locus_tag="TVB59_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009376.1"
                     /translation="MGKYQLDYKGMQQVERFHEKHSVAKTDKKSRVQQLRAQFLEKAK
                     QSKK"
     gene            30461..31396
                     /locus_tag="TVB59_000437"
     CDS             30461..31396
                     /locus_tag="TVB59_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEL1009377.1"
                     /translation="MLDIGIVGLGAISQKAYLPYMRQLRGINWHLSTRNALVRQEVGQ
                     LFGCARLYSTVNELLEAKLDGVFIHAATKAHLELASLFLQKGIPVYMDKPLTEDFFST
                     QALYQLADKHNTFLMADFNRRFAPGVKKLSTLSTKRKVVVEKNDINRPGDKQFKLFDF
                     FIHPLDTALFLVDRRLVAGYFHYQLTDNDLLSQVSVTLRTEQTIISAAMNLQSGSRRE
                     VMEVQTPKETYHLENLETLRAYRGVDQEIKGFSAWDTTLSKRGFEAIVDSFLQAVKDG
                     VNPVKPETSLLSHWICHQICQSHEADGILDVSLPL"
     gene            31409..31903
                     /locus_tag="TVB59_000438"
     CDS             31409..31903
                     /locus_tag="TVB59_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1009378.1"
                     /translation="MKLRRPKKQDEASVLEMMAEFEDYQSPHDGGFWNAEHFDYEKWL
                     ESNALMEAGLAIPENWVPAIQLVAFADQQAIGFVNVRLRLNEQLLVKGGHIGYSVRPS
                     QRGKGYAKLMLKEALQLARQKGIREVLVTCHCSNSASRSVILANGGQLKDCNKGIERY
                     WIKA"
     gene            31913..32527
                     /gene="nrdG"
                     /locus_tag="TVB59_000439"
     CDS             31913..32527
                     /gene="nrdG"
                     /locus_tag="TVB59_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEL1009379.1"
                     /translation="MKENCWNSPKPKEWTSEALSQGRVIDYKAFNFVDGEGVRNSLYV
                     SGCMFHCKGCYNAATWSFKAGIPYTKELEEQIMTDLAKPYVQGLTLLGGEPFLNTGIL
                     IPLIKRIRKELPEKDIWSWTGYTWEEMMEETQDKLELLSMIDILVDGRFDITKKNLML
                     QFRGSSNQRIIDVKKSLAAGEVVIWDKLNDGDQSFEQMSRDDLI"
     gene            complement(32985..33716)
                     /gene="yaaA"
                     /locus_tag="TVB59_000440"
     CDS             complement(32985..33716)
                     /gene="yaaA"
                     /locus_tag="TVB59_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEL1009380.1"
                     /translation="MLTFLIPTAKEMKPVPPCYPHQLPQKSLPILEAMAELSLEELAR
                     AYSIRIEAASKEAKRLKAIAQGQSSAYPAYQLFNGLMYRHLKRDNLSKDQQDYLSKQV
                     YITSSFYGIIPTDEKIAEHRHDFHTKVTINGQSLKHYWRPIYDQFAKDHKQIISLLSN
                     EFRDVFSKEYQKLWISPKFMEERSGQLKTHSTISKKARGAFLTACLENNVQTKEALKQ
                     LSFAGFCYNEELSTETNYYYIKKES"
     gene            34170..34373
                     /locus_tag="TVB59_000441"
     CDS             34170..34373
                     /locus_tag="TVB59_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1009381.1"
                     /translation="MENRIQELRKSRGISQADLADMMCVTRQTIISLEKGRYNASLEL
                     AYKLATFFNLTIEDVFLFEEKGE"
     gene            34375..34828
                     /locus_tag="TVB59_000442"
                     /pseudo
     CDS             34375..34828
                     /locus_tag="TVB59_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516426.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            34838..35512
                     /locus_tag="TVB59_000443"
     CDS             34838..35512
                     /locus_tag="TVB59_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEL1009382.1"
                     /translation="METKHSAVKVIISKLKWFGLALLVFMLEQAPTFLITKEQPMWQT
                     LLLVVIFLLISGGTYYLAVKLHIVGDQAIPKNDYRALWIGLGVVAVFVVKMIGGILLF
                     LEHGPGANTVNQAALEQAGLSPILMVTLVAIVAPIVEEIAFRGLLYGKLFGAESYLGL
                     IFSSIMFGLIHVPTDFGSWFIYGGMGLVLGFVFHKTKKVEYTILIHFLNNALAVLIML
                     LLPYLQ"
     gene            35542..35979
                     /locus_tag="TVB59_000444"
     CDS             35542..35979
                     /locus_tag="TVB59_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009383.1"
                     /translation="MKNDRWIDKKYQRWEKVYKRLGHSLLTIGVLVGTYGIFLIIQGN
                     HQTGFLLFILGPILLIASCLCYYVFTEPTSLREYLINSYDERNRAIRQKAQAYCFCLF
                     AFLFLMLAIFFPNMTIKELFGYNLPLIVFNLYVMIRAWVSKHM"
     gene            complement(36202..36975)
                     /locus_tag="TVB59_000445"
     CDS             complement(36202..36975)
                     /locus_tag="TVB59_000445"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEL1009384.1"
                     /translation="MKIGFIGVGKMATAIIQGLTHTPHELIISGSSLARSKEIAGQLH
                     LSYAQSHQELIDQVDFIILGIKPQLFETVLSPLQFKQPIMSMAAGISLDRLAQLTSSH
                     LPLLRIMPNMNAQILQSTTALTGNDLVTADLLATAKELTNSFGTTFEIAEKDFDTFTA
                     LAGSSPAYLYLFIEAMAKAGVKNGLPKDKALSIVSQTVLASAKNLLVSTDSPHDLIDK
                     ICSPGGTTIAGLMDLEKTGLTHSVCSAIDTTIKKAKDLS"
     gene            complement(37059..38126)
                     /gene="pepA"
                     /locus_tag="TVB59_000446"
     CDS             complement(37059..38126)
                     /gene="pepA"
                     /locus_tag="TVB59_000446"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEL1009385.1"
                     /translation="MIDLFSKIKEVTELDGIAGYEHTVRDYLRAKITPLVDRVEVDGL
                     GGIFGIKESKADQAPRILVAAHMDEVGFMVSEIKADGTLRVVEIGGWNPLVVSSQRFT
                     LYTRAGQAIPVISGSVPPHFLRGANGAASLPAVSDIVFDGGFTDKTEAESFGITPGDI
                     IVPQSETILTANKKNIISKAWDNRYGVLMVTELLEALKDQTLHNTLIAGANVQEEVGL
                     RGAHVSATTFDPELFFAVDCSPAGDIYGNLGHIGDGTLLRFYDPGHIMLKNMRDFLLT
                     TAEEAGVAFQYYCGKGGTDAGAAHLKNGGIPSTTIGVCARYIHSHQSLYALDDFVEAQ
                     AFLQAIVKKLDRSTVDLIKKY"
     gene            38471..38818
                     /locus_tag="TVB59_000447"
     CDS             38471..38818
                     /locus_tag="TVB59_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEL1009386.1"
                     /translation="MAEIVSFCSSLLFPFCDKMKGMNGKKTRIVSGLIGLGLLAGLGL
                     RLKEVYQERERQRVLVELRAFFSALGEIEVLYINSFSSKRDDVTGGLVMTDGKTYTYH
                     YHKGSIDFKEDLT"
     gene            38815..39132
                     /locus_tag="TVB59_000448"
     CDS             38815..39132
                     /locus_tag="TVB59_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEL1009387.1"
                     /translation="MIIPTSKEELARLIETEPRLVLFFTADWCPDCQYIYPVMPELEA
                     ENPDMTFVRLDRDDFIDLAQDWQIFGIPSFLVMEKGQEKGRLVNRLRKTKAEISDFLA
                     AYH"
     gene            39147..39773
                     /locus_tag="TVB59_000449"
     CDS             39147..39773
                     /locus_tag="TVB59_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEL1009388.1"
                     /translation="MIFAYNKEQVGDVLMVILEDKKDIKRQVERKGRVARVFAEETGQ
                     TLAWNIFEASALIAVEGNGQVFLSEEELAILNAELAQEGFTERLEASPAPVFVVGQII
                     EMIPHPDSDHLNICQVQIAPDKAVQIVAGAPNAAVGLKTIVALPGAMMPSGSLIFPGK
                     LRGKESFGMMCSPRELALPNAPQKRGIIELGDAAAVGEAFDPAKHWQS"
     gene            complement(40076..40789)
                     /locus_tag="TVB59_000450"
     CDS             complement(40076..40789)
                     /locus_tag="TVB59_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL1009389.1"
                     /translation="MTINLKAYQDMLTRPWGKLMYDLIFAQLGPIAGKTILDFGAGFC
                     ITAEALAVQNEVTAIEPNPDLLFAQKQESIHKIKGSLEALEKLPDQAFDMIICHNVLE
                     YIAPKEHAIYLAQMERLLKPKGQLSLIKHNQVGKVLHSVIFEHDYDKALNVLNGQAFE
                     SLSFAAGQTYSIDDLLRKTDLKLQGYRGLRTCYGLQPNEVKAKPDWLEVLRTIELAIC
                     DQKPYKDMAFFQHVTLSKA"
     gene            40901..41296
                     /locus_tag="TVB59_000451"
     CDS             40901..41296
                     /locus_tag="TVB59_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL1009390.1"
                     /translation="MYNKVILIGRLVAKPELNKTLTDKQVVRFTLAVNRRFKTTTGER
                     EVDFINAVAWGGLAETLASYASKGSLLSLDGELRTRKYDKAGQTHFVTEVLCHSFQLL
                     ESRAQRAIRENNAANDLIDLALEEEKLPF"
     gene            41743..42717
                     /locus_tag="TVB59_000452"
     CDS             41743..42717
                     /locus_tag="TVB59_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEL1009391.1"
                     /translation="MRFKQLSLTAFIGLLAMLLTACRQETNQTHQAARVGIIQYAEHS
                     ALDAAREGFIEALEQGGFREGKNLTITTKNAQGDQANLQTMVEQLAGKNDLQLAIATP
                     AAQALLNMDSETPAVFTAVTDPVSAGLVDTLAKPGGNMTGSTDATDVENQIDLLTKAL
                     PQARTVGIFYNSSEVNSEIQAKKAKRELEKKGLKVLMKTVTTTNDVQQVMTSLASQVD
                     AVYLPTDNTVASTATTIGDILKEAKIPSMGSDAAYLSAVLFTSGVDYHAIGMQAGQQA
                     VDILKGKKPASIQVAKPQKASIAVNDDMARLLGIDPEVIKALASNGAN"
     gene            42735..43697
                     /locus_tag="TVB59_000453"
     CDS             42735..43697
                     /locus_tag="TVB59_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEL1009392.1"
                     /translation="MKKGSYLILLVLAGFVLVACRSTASPRKVNQSHVNIGILQYMEH
                     DSLTAARRGFEAQLKAAGYTKGDKLSLHYQNAQGDQANLQTISEQLVKQNDLILAIAT
                     PAAQALATVSSDRPIVFTAVTDPISAGLVDRIKKPGGLITGTSDQAPIAKQIDLLAQA
                     LPEAKTIGILYTASERNAEVQVKEAETLLTKVGYRVIKKGIATSNDVQDTAASLMRAV
                     DALFVPTDNTVASTMTMLGELSLANKVPIIGGSTDMVDAGGLLTYGIDYESLGRQAGE
                     MAIKILRGQDPASLAVEYPKTVKLHINQAMADKLAIDTSTLSVD"
     gene            43812..44696
                     /locus_tag="TVB59_000454"
     CDS             43812..44696
                     /locus_tag="TVB59_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1009393.1"
                     /translation="MSLILSSLSQGLLWSIMAIGVYLTFRILDIADLTAEGSYPLGAA
                     ICATGIVSGVSPLLATFLAFIGGLLAGLVSGLVHTKLKIPALLTGIITLTGLYSVNLK
                     VLGRANVALLRQRTLVTQLYDLGFTKLAAVLIMGFVFVTIVIFLLALLMKTQLGLALR
                     STGDNNPMSEANGIKTDQMKIMGYMLSNGLIALCGALLCQNNGYADLNAGVGTIVIGL
                     ASIIIAEVMIRQLSIGWRLASIVLGSIVYRLIILAILAIPGMDADLVKLFSAMLLAAV
                     LFVPELQQRLRLRKTSLG"
     gene            44705..45508
                     /locus_tag="TVB59_000455"
     CDS             44705..45508
                     /locus_tag="TVB59_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1009394.1"
                     /translation="MSAILSIKAIHKTFEAGTINENHVLRGLSLDIEEGDFISVIGGN
                     GAGKSTLMNTLAGTLAFDQGDILLEGKSIKHLSAAKRAKDISRVFQDPKMGTASRLTI
                     EENMAIAYRRGKSRGLGWGVKERERQIYRQALQELGLNLENRLKAETQFLSGGQRQAL
                     TLLMASLAKPKVLLLDEHTAALDPKTSTMVMALTKQLVETHGLTTLMITHNLENAIAY
                     GNRLVMLHQGNIVVDIKREEKAKLTVDHLMALFHQNSGHTLLDDALVLG"
     gene            complement(45607..46611)
                     /locus_tag="TVB59_000456"
     CDS             complement(45607..46611)
                     /locus_tag="TVB59_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009395.1"
                     /translation="MLSRHNIVQRSLVKHLLLLATLLGSLGLGNSLSKADSQDHLHVN
                     LYLIQSDSNLKRYGKRIIDKAIEKVKARPRLKFSSEYEVNQFLNNISRLHPELRLTEQ
                     ETQSNKQQTPSKETRRAEASRNSNTSRPAASLSSYRRYSDAQILANIKAELEKSDYDA
                     IKQFKDDFINRLHSQEIQLNPYRDSSKIPALLFRELQYYLKLHPEMIYHLDGINLSPE
                     VADSFVSRLANAYSLDNMLSILQEARAYGQGIIDTIAKRAEAKAILTEHKNTYKDRNQ
                     RVSEDYYSTAFHEIDEAITIQQLNKAIEIVENEAYRIRNKSFDYNRRHHGFITLRKIS
                     "
     gene            complement(46897..47538)
                     /locus_tag="TVB59_000457"
                     /pseudo
     CDS             complement(46897..47538)
                     /locus_tag="TVB59_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635233.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
     gene            complement(47559..48536)
                     /gene="dusB"
                     /locus_tag="TVB59_000458"
     CDS             complement(47559..48536)
                     /gene="dusB"
                     /locus_tag="TVB59_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEL1009396.1"
                     /translation="MTRLNSPFRIGHVEIPHRTVLAPMAGVTNSAFRTIAKEFGAGLV
                     VMEMISEKGLLYNNEKTLHMLHIDDNEHPMSIQLFGGDAEGLKRAADFIQSHTKADIV
                     DINMGCPVNKVVKNEAGAKWLRDPDKIYHIIQEVTSVLDIPLTVKMRTGWADSSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGTCDHETLARVSRAITRIPFIGNGDVRTVQDAR
                     FMIEEIGVDAVMIGRAAMNNPYLFTQINHFFETGEVLPELPFAKKLDIAKDHLKRLIR
                     LKGEAIAVREFRGLAPHYLRGTAGAAKIRSAVSRAKTLAEVETIFAQIH"
     gene            complement(48523..49395)
                     /gene="hslO"
                     /locus_tag="TVB59_000459"
     CDS             complement(48523..49395)
                     /gene="hslO"
                     /locus_tag="TVB59_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEL1009397.1"
                     /translation="MDKLIKTISASGAFRAYVLDCTETVRYAQERHHTLSSSTVALGR
                     TLIANQILAANQKGDSKVTVKVIGDSSFGHIISVADTKGHVKGYIQNPGVDIKKTATG
                     EVLVGPFMGQGHFVTITDYGTGNPYTSTTPLITGEIGEDLAYYLTESEQTPSAVGLNV
                     LLDQEDKVKVAGGFMLQVLPGASVEEISHYEKRIQEMPAISTLLASENHIDALLAAIY
                     GEEPYKRLAEEQLSFQCDCSRERFASALMSLPKADLLTMLNEDKGAEIVCQFCGTKYQ
                     FDQTDLEVLINDKA"
     gene            complement(49645..>50820)
                     /locus_tag="TVB59_000460"
     CDS             complement(49645..>50820)
                     /locus_tag="TVB59_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HEL1009398.1"
                     /translation="LHNLSQLPVLVLSQNLELLQAYDDEERRFPYYELIKTLDIPSNT
                     ELTCYEGTLEESSLMFPIGDKFIFIGPFYTSFFQDSYKEELADSFLKRYPDKSKKELV
                     GYISTIPHFPASHIRSLLIAVDAFFDTNFEMSCQQSINDLLEEAQLIWEDPHIIANLE
                     LENTPSFHVPAVLNYLNHIIDLVKLGNTELLKHEINCIPSSDVVSSSIPALRAEKNLS
                     IIYFIKLLELSFTENTDVAKNYERIKHFMNLTEKATDLLKVLQIRAAAIISLSESLTN
                     KSVSDKQQIYNSILYYVDKHLYSKLKVSDIAKHLYISESHLRAVFKMYSSISLQTYIL
                     KEKVQEAKLLLRRGVPAGEVAKLLYFYDTTHFLKTFKKYTDTTPHDYLAHYQQSITK"
BASE COUNT        14545 a         9125 c        11631 g        15519 t
ORIGIN      
        1 gttttgataa aatgaatcta tgaaatgagg gagcaataat gactgaagta acagtgcgta
       61 aaccgatgga aacaatggaa gtttcatggg tagtcattta aatactctaa agtgggctgt
      121 ttttatcagc ctactttaat atttttagga gggtaaaaaa tgaattatag cagaccttgt
      181 attaaagata tttatccaat ttataaactg agtgatacca tgtttcgaat aggcgctcaa
      241 attaatatta cgacggaatt taacgattca aattatgaaa caggtgcttc atttacacat
      301 aagctttggc cacatttcaa agagtgtccg gcttgtggtc atggcaacag taatgattgg
      361 gaaatattta gtcattatgg gtaggagtta atcaatggaa caatatgaat taatggtgag
      421 gtcactttca aaaaggtatg ccagagatgg ctcttatgcc aatagggatt tacattgtgt
      481 ctttaaatcc agtgaaataa cagccttgat aggtcataat ggagctggta aaacaactct
      541 actaaaccag attattggta atataaaacc tgatgtgggt gatatttcat ttctagactg
      601 ttcgtttgtc aagtccccta aaattgctag aaaaaatacg tcaatgatgc ctcagctaca
      661 tgccccctta aaaggaatca caattaaaca ggctatttca tcaattggaa aaatcagagg
      721 gctgtccgga aaattattgg agacagaggt tcaggaatta attcaagaac tcggtcttat
      781 taagtggcaa aatactatcg gagagaaact ctctggtgga ctaaaaagat tgacgtcgtt
      841 tgcaatggct gttattgctg ctccgaagat tgttttacta gatgagccga caaatgatgt
      901 tgatcctata agacgtataa aattatggtt atacttaaaa aagatggcgg caaagggaca
      961 tatcgttatt gttgtcaccc ataatatttt agaggttgaa aaatatgcag atgcttatta
     1021 tttgcttgaa aagggggaag taaaaagttc aggagcggta aaaaccctat ccagcaatcc
     1081 aaagagtaga atatccattt tatttagaga tcaaaaagcc ttggaagaat acccatttgc
     1141 ttactcactt ggtggggatg acaatgaagc tataacaata atggataata aggaaatgac
     1201 agcattattg aattggttag gcatacattt gtcatcagat accattgttc aatatagtat
     1261 cacgacgtta gggttaaatg attattatga ggagctgtca gatgaagaag attagtgtta
     1321 cttaccaatt tctaagcttg ttaaattgga gctttattcg ccataaatcg ttgatattat
     1381 tgtgtagcgt tattcaattt tttatgacaa ttgcactggt ttacggttat tcacttatta
     1441 ttgctgatga tactgtgcaa acagtctact atcttgcttc tggctcagta acgattggta
     1501 tgattaccat tggctgtacg gtatcagcac aatcaatcag tagtgataaa agagatggca
     1561 ttgtgagcta tattcaaacg ttacccgtcc taagaagttt gatcctgcta tctgatctat
     1621 tgatttggac attaactgct ttgattggtg ttggtgtgtc aattgcggtt gtttatttaa
     1681 aatttcaaat attgccccag ctgtccttag cgacgtttct tattttgcca ttagttttaa
     1741 tgacaatgat cagtatgggt tttgccattg cttattggtc aactccaagt acgatgatgc
     1801 tggtaaccca attattgttg atgattggct tattgttttc acctataatg tatcctgcag
     1861 aacgtatacc tgaggtgatt ttaaggggat atcattttct gccatttata ccagcaggag
     1921 acttgattcg agagacggtt tatttggggc attccatttc agttgtcaag cttgtggtgt
     1981 tactgttatg gctggttgcc actgccttac tttcagtcaa ttggctaaac aggcaaagct
     2041 aaggtatagg ctctgctatt tcttaaaaac tctactcaaa tgggtggggt ttttaattgt
     2101 tttttgttat aataagtggt aatgatattt ttaattagag aaaggaacaa agacaggtag
     2161 ggagtgttga ctctttattt gctcttggta tcttatttat gaagcgtagc atgtatgcag
     2221 gacacgtccg aaaggaacat attggaagaa cgattgtttt aaaaggttgg gtaagtcgcc
     2281 gtcgtgattt gggcggcctt attttcattg atttgcgtga tcgtgaagga gtgatgcagc
     2341 tggttattaa tccagaggac gtttcaggtg atgtgatggc gactgctgag cgcttacgca
     2401 gtgaatacgt gattgaggtg gaaggaagtg ttgaggcgcg tcagcaggct aatgataagc
     2461 tagctacagg tgcagtggag ctaaaggttt caggcttgac cattcttaat acagctaaaa
     2521 cgacaccgtt tgaaatcaag gacggtgttg aggttagtga cgatacgcgt ttacgctacc
     2581 gttatttaga tcttcgtcgt ccagaaatgc tggaaagctt taagcttcgt gccaagacga
     2641 cgcatgttat ccgtaattac ttggataatc ttggatttat tgatgttgag acaccgatgt
     2701 tgacaaagtc aacgccagag ggagcgcgtg attaccttgt accaagccgt atcagccagg
     2761 gacatttcta tgctttaccg caaagcccac aaatcacaaa gcaattgtta atgaatgcgg
     2821 gctttgatcg atattaccag attgttaagt gcttccgcga cgaagattta cgaggagatc
     2881 gtcagcctga gtttacacag gttgacttgg aaacgtcatt tttatctgag caagaaatcc
     2941 aagatattgt tgagggtatg attgcaaagg ttatgaagga tacaaagggc atagaggtta
     3001 agctgccatt tccgcgcatg gcttatgatg acgccatgaa tcattatggc tcagataagc
     3061 cagatacacg ctttgatatg cttttacaag acttgacaga tcttgtcaag gagattgact
     3121 ttaaggtatt ttctgaggca caggctgtta aggcaattgt tgtcaaagga catgcggatc
     3181 gctactcgcg aaaggacatt gataagctga cagaatttgc taagcaattt ggtgctaagg
     3241 gtctggcatg gctgaaggtg gttgatggtg catttactgg accaattgct aagttcttga
     3301 caggtgtgaa aagtaagttg acagagtctt tacagcttga gcataatgat ttggtcttgt
     3361 ttgttgcaga caccttagag gtagccaaca ataccctagg tgctcttcgt acacgtattg
     3421 caaaagagct tgacatgatt gacatgtctc agtttaattt cctatgggtg gttgactggc
     3481 ccatgtttga atggtctgaa gaagaggagc gttacatgtc tgctcatcac ccatttacat
     3541 taccaacagc agagtcagcc catgagctag agggtgattt agccaaggtt cgcgctgttg
     3601 cttacgatat tgtcttaaat ggctatgagc ttggtggcgg aagccttcgt atcaaccaaa
     3661 aagacatgca agagcgtatg tttagagcac taggcttcac agctgaggag gccaatgagc
     3721 aatttggctt cttactagag gctatggagt atggcttccc accacatggt ggtcttgcta
     3781 ttggtcttga tcggcttgtc atgctgcttg ctggcaagga caacattcga gaggttattg
     3841 cctttcctaa aaacaataaa gcatctgatc caatgacaca ggcgcctagt ctggtatctg
     3901 aaaagcaatt agaggagctt cagcttcaaa tagaacatca tgattaaaaa aacaacctat
     3961 aggaaaagag taaaatacct gattaataga ggagccaaaa aaattggctt gcttcatgcc
     4021 gtaaaaagca tttccaagga gaagtataca gagaaaattt cggcctcttt actctatggc
     4081 atattgtcta gtatagctgt taatttcttt ttccaaccgg gccatgtcta ctcaagtggt
     4141 gcaacaggac ttgctcaggt tatctctgcc atcagccacc atttatgggg ctttgagatt
     4201 cctgttgctt tagcttttta cgtgactaac attcctcttt tagtcttagc ttggtataag
     4261 attggtcata aatttacgat ttttaccttt attaccgtta gtatgagctc tttctttatc
     4321 caaatcatgc ctcaggtgac cttgacgact gacccactga ttaatgctat atttggtggc
     4381 ttggttatgg gtttggggat cggtacaggc ttcaagtctc gcatttctag tggtggtacg
     4441 gacattatca gtctgacact tagaaagaaa acaggaaaag atgtcggtaa cctttcattg
     4501 atgatcaatg gtgtgattat ggcttttgca ggactgttgt ttggctggca gtatgcgctt
     4561 tattcgatgg tgactatttt cgtttctagt cgagtgactg atgcgatttt taccaagcaa
     4621 aagaaaatgc aggcgaccat tgtgaccagc tgtcctgaca aggtgatcca catgattcat
     4681 aaaaagctgc accgaggggt aaccagtatc aatgatgctg aaggcaccta caagcatgag
     4741 cataaggctg ttttaattac gattctcaca cgtgaggaat atagtgaatt taagtggctg
     4801 atgcttaaaa cagatccaaa tgcttttgtt tctgttgctg aaaatgttag aatcattggt
     4861 cgctttgtcg aatcagatga agactaagaa ataggtatca atatgccagc taataagagc
     4921 ttaaagctta aaaattgttg ttttattatt cttggctcag ctatttatgc ctttgccttt
     4981 gtctactttt acatggcaaa tcgtattgct gctaatgggc tagcgggact gacgcaggtt
     5041 gctaatgcct tgtttcagat caatccttca ataacgggtt atctgattaa tttgcctctc
     5101 gtcctgttgg gtgcaaggct ctttggcaga cgggcaatgg tgtatactgt gaccggtatt
     5161 ttatcacttt attggtttgt ttggctgttt caacagctcc ccctttttat tgacttagat
     5221 catgacaatt tagtagtgtc cttgctggca ggaattcttg gtggtttagg tggcggcatt
     5281 gtttttagaa atggtgggac gattggtggc tcagatatta ttgctaagct gatagaggat
     5341 aggtttggct tgcagctcaa tcaagcctta ttagggattg atatttttgt cattgtggtt
     5401 tctttgacct atatttcaat accgcagatg atgtatgctt tgattgctag ctttatgtat
     5461 agtaggattg ttcatctggt gcaaaatggt ggctattctg cacgcggaac ctttattatt
     5521 tcagattatt ctcagactat ttcacaattc attatggagg agctcggtag aggagtcacc
     5581 tatttacatg gtgagggtgc ttactctggt cgtgagaaac aggttattta tgtagctcta
     5641 ggtcgatcag atgtacgaga gctaaaggcc tttatagcac aggttgatcc caatgctttt
     5701 gtttctttct ttgatgttaa cgaagtcaat agtccagaat ttattgccac aaaaagtaaa
     5761 taccataaaa cgaaaaaaag ataaaggctg gaatatcaca ttcatagcct ttgattatgc
     5821 taatgaaagc gcttggctat taagcttatt gtagtgtagc tattaaatgg ccgtccttga
     5881 gctttcatct ggtacctaac aaatgtaatg aatagtgagg aaagtgaatg acaaatcttg
     5941 acaaatggca tcgtgtaaga gagctattat taattgcggt gggtgttgct atctatacct
     6001 ttggttttgt taatttcaac atggctaatg aattggctga gggtggcgta gctggaatta
     6061 ccttgatttt gcatgctcat tttgggatca atccggctta ttcgtcactt ttatttaatc
     6121 tgcctttatt tatgttaggg gctaagattt ttggaaggcg ctccctagcc ttaacgattt
     6181 atggaaccgt tcttatgtca gtctttatct ggctgtggca aaaggtgcct atggagcttg
     6241 gtttagagaa tgatatgatg cttgttgcgg ttgttgcagg cttgtttgca ggaattggta
     6301 gtggccttgt ttttcgatat ggagcgacaa ctggtgggac tgatattatt gcccgcattg
     6361 cagaggaaaa gtttggtgct aagctggggc aaaccctgtt atttgtagat gccttggtat
     6421 taacagcctc tctcacttat gttgatttga agcatatgct ctatacatta gtggctagct
     6481 ttgtctttag ccagatgatt agtgttgttc aaaatggtgg ctataccatt cgtggtatga
     6541 ttattatcac taagcagtcg caagccgcgg cgcaggcgat cttgacagaa atcaatcgag
     6601 gagtgactta tttaaaggga caaggcgctt attctggtca tgattataat attatgtacg
     6661 tgacgctcaa tccaacagag gtgcgagagg tgaagcgtat tttagcagag ctagatccag
     6721 acgcctttat ctctattatt gatgttgatg aggtaatcag ctcagacttc aagattcgtc
     6781 gcaaaaattt tgacaaacca attgagaagg ctttacagaa aaaatccaac atgttaaaat
     6841 aaagaaaata agcagaaata agaggttgag aaaagccatg attaacaatt aactcattgt
     6901 caagcactaa tctatgatta acagcaaggg attagtgtct gctttgaggc ttgggaatca
     6961 gggctttttg tgtgcacttt ttcaggcctt tctgatgata gaaaggaata aatatggaag
     7021 cacttagtat tcagcattac gctttagata cagcagaaaa aaacttattg acaatagatt
     7081 ctcttacatt gaatcaaggt gagagggttt tcatcattgg tgataatggg gctggaaaga
     7141 ccagcttttt aaagacaatt atcggagaaa gcactaacta tagtggcttt ttgcaggtgc
     7201 atggagatat tgcttatgtt ccgcaaatca agtccactag ccctcagtca ggaggtgaga
     7261 gggcgatgtc ttacctaaaa gaggcttttc aagcaaggcc ttctctgtta attttagatg
     7321 agccaagctc ttatttagac catgctaatc gtgattggtt gattaatcaa ttgaaacgct
     7381 accgaggaac cttgctggtg gttagccatg atcggtattt gatcaatcaa ttgagtcaga
     7441 aaatatggtt gcttgagcat caaacgatca agacttacca tggcaattat gatgattatc
     7501 agcgttctag acagctagag gaggataagc agctaagagc ttttctggaa taccaacgaa
     7561 agactaatca actgaaaaaa agcctgacca gaaaaaaagt gcaggccaac aaaatggctg
     7621 taaagaaaaa gtcggtttct cggtcagatt ggaaaaccaa ttcctttgcg ggcagctatg
     7681 attcacaggc caaggctatg gcaaaagcag ctaaagctat ggaaaatcga ctcactcgaa
     7741 tgaaagaggt taacagtccg cgcaaaaagg cttgggcaaa attaaaaaag gatccaaacg
     7801 aaggtgcact accaaatact cttttacacc tacaagaagg tacccttaca agggaccatc
     7861 agttattgtt tgactatcct ggtattgtga tcagatcaca tagcaggata gcgattatcg
     7921 ggagaaacaa ggctggtaaa agcagctttt tagatcagct ggcagcccag gccttgtctg
     7981 gattttatgc gcaaaatcta aggataacct attttaaaca ggaccaggct gacttggagc
     8041 cggatcagac agcagtagag ctcattagtc ggcagtccag ccaagatagg gtcaccattt
     8101 taaattatct agctatgatg ggcattgatt atgataaggc caatcaaaag gtagctgtct
     8161 tatctggtgg ggaaagggtt cgtttggcgt tagtggctgc cttgctgaca gatcatcagc
     8221 ttttgatttt agatgagccg acaatttatt tggatcttgt cgctattgag gctttggagt
     8281 cttgcttgat tgactatcca gctgctcttt tgttggtttc tcatgaccta gcatttgtta
     8341 acaaggtagc aacagaaatt tatgaggtta aggatcatca tttaacagcc tatcattttg
     8401 aagactagca aaaaagccta ggctagctta tcctcgctag cttaggctta ttagtctaca
     8461 tttcatttgg tgcctcaaca cccaatagac gaagcgcttc tttgaggacg attgcagttg
     8521 catagcaaag cgctaagcgg ttgtcacgtt ctggatcgtc ttcgaggata cgggtatgcg
     8581 cataatattt gttaaagctt tgtgccaagt gaatagcaaa ttttgccatg attgatggct
     8641 caaagttatc aaaagcacgc ttgatgatac gtgggaagtc ctggataagc ttaatgattt
     8701 cccagctttc aggatcatta aggctatagc ttgtatcggt agctggcgta aagcttgctt
     8761 tacgcaggat agattggata cgtgcgtgtg catattggac gtaaggaccg gtttctcctt
     8821 caaaggatac cattgcttca agatcgaagt catagccatt catacggtct gtttttaaat
     8881 catagaactt gatagctccc acaccaacag catgagctac tgcttccttg ttggcaagct
     8941 taggattttt agcttcgatt tggtttgctg ctctgctgat ggcttctgca accgttggct
     9001 caagcaaaat gacattaccc ttacgtgttg ataattttgc accgcccttt gtcacaaggc
     9061 caaaagcaac gtgtgtcatg tcatctgacc aatcgtagcc catttcttta agaacagcct
     9121 ttaattgctt gaagtgtgca gcttgctcgt tgccaaccac gtaaactgat tttgcaaaat
     9181 cataggtacg cttgcggtaa agggcagcag ctagatcacg agtaatataa agcgtagctc
     9241 catctgattt tttaatgaga gctgggtgct caataccata tttttcaagg ttaaccacct
     9301 tagctccctt agattcgact agtaggcctt tgtcctcaag aagctcaagg acctcatcca
     9361 ttttatcatt gtagaaggct tcaccattat agctatcaaa gctaactcct agctggtcat
     9421 agagtcggtt aaactcaatc aagctttcat cgcggaacca ctgccaaagc tctgtagcct
     9481 cttgatctct ctcctctagc ctgcggaacc attcacgtgc ctcctcatca agactaggat
     9541 cagtttctgc ctctgcattg attctcacat agagctttaa gagctcatca attgggtgtg
     9601 cttgaacagc ggcctcattt ccccacttct tatacgctac aatgagcata ccgaattgct
     9661 tgccccagtc acctaggtga ttgattttaa caggcttata gcccattttt gcaaagatat
     9721 gagcaagact gtccccgata actgttgagc gcaggtgacc gattgaaaat ggcttagcaa
     9781 tgttagggct ggacatatca atagcaatat gacgtccttg tccttcatcc tgttgagcat
     9841 agtcagctcc gtcagcaatc acctgtgtaa gaacctgtgc agaaatgcta gccttatcta
     9901 aaaagaaatt gacataagga ccaacagcag caaccttctc aaattggctg gcgtcaatcc
     9961 tttcagctaa atcactagca atagcttgtg gtgctttgcg aagcgccttt gctagactaa
    10021 aggctggaaa ggctaagtct cccatgtcag aatttttggg tgtttcaagt aagttaaaaa
    10081 tggcagcctg ctctagttca ggaacaatct tagcaatctc agctgcaatc agagttttag
    10141 tgtccatatt gcttctccta aaaatagttt gtcaccctat tctaacacat ttcttggaaa
    10201 taaacgaggt gtctattgag aaattatact agaaggcttg taggtgtttt ggggaacaaa
    10261 gctaaagaat tagagcagca aagcttgcca aatctaaggg tctaatgata tgagcaagaa
    10321 ataatgcttc cttaaaataa agcaaattga cagagctgag atgaaatact accatttttt
    10381 tgttataatt tgagaggata attatacatt ggggagatat atcatgaata aaatagaacg
    10441 gcagcagcaa atcaagcaac ttattcaggc tgagcacatc ggtacacagg aggagattag
    10501 acggcttctt caaaaggatg gtatcgtggt cactcaggct accctatcac gagatttaag
    10561 agaaatcgga ttacttaaat taagagatga cagaggtaag ctatactata gtctttctga
    10621 gcctgttgcc acaccattta gtccagatgt gcgcttttat gtcctaaagg ttgaccgggc
    10681 gggctttatg ctggttctcc ataccaatct gggagaagca gacgtgttgg caaatcttat
    10741 tgacaatgat gccattgagg acgttttggg cacgattgcg ggtgctgata ccttacttgt
    10801 tatttgtcgt gatgaggaga ttgccaagcg ctttgaaaaa gatttagctg ctggtctata
    10861 atatgcctta ccgcgaatcc ttacatcagc tgatagcagc actggaaaag cactcaagca
    10921 ttatagctta taaggaggct cagcagcact tgcttcaaag gactgattat aatcaaaagg
    10981 cctatcagat gaagcgacat caacaggaca cctatctttt tcgtcaaatc gctaaggata
    11041 aagcagctga agaatcagct tttaaggctc agcaattacg agaagattta gatcatcaac
    11101 cattgataga tgattatcgt gacaaaatgc aaaacgctag tgacttggtt cggtacatta
    11161 cagggactat agaagatgaa ttaaataagg agttcaatga tggcaaaggc taatgtttct
    11221 cccggaatgc agcagtatct ggacatcaaa aaggattatc cagatgcttt tttgcttttt
    11281 aggatgggag atttttatga gttattttat gaagacgctg ttaaggcagc gcagatttta
    11341 gaaatcggct taaccagtcg taataaaaat gctgacaacc caattccaat ggcaggtgtt
    11401 ccctatcatt ctgtccaaca atacatcgat gttttaattg atttggggca taaggttgct
    11461 attgctgagc agatggagga tcctaagcaa gcggtcggtg ttgttaagcg tgaggtggtt
    11521 caggtcatta ccccagggac agctgtggac tcaagcagac ctgatagtcc caataatttt
    11581 ttggtggctg ttgattttga tggcaaggct tatggcctgt cttatatgga cgtctctaca
    11641 ggagaatttt ttgctacaga cctagcagat tttgccagtg tcaaaagtga gattcaaaac
    11701 ctgaaggcaa aagaggttct tttaggcttt gaattatctg aagaagagca ggctatttta
    11761 gtaaagcagc tgaatctttt gctgtccttt gagatgacag cactagagga ttcgcctttg
    11821 attgatcatc agctaacagc agtcgagctg tctgcagcag gtaagctgct acactatgtt
    11881 catcaaaccc agctgcgtga gcttagccat ctacaggcct tggtgcacta tgatattaag
    11941 gattatttgc agatgtctta tgcaaccaaa tcaagccttg acctgcttga aaatgctcgt
    12001 actggtaaaa agcatgggag cctttattgg ttgcttgatg aaaccaaaac agccatgggt
    12061 atgcgtctat taagggcttg gattgatagg ccacttgtga ctagtgaggc gatcctagaa
    12121 cgtcaggaaa ttatccaggt gtttcttaat gcttttatcg aaaggacaga tctaagcgat
    12181 agtttaaagg gtgtttacga cattgagcgc ttgtctagtc gtgtatcttt tggaaaagca
    12241 aaccccaagg atctattaca gctaggtcat actttggcca aagttcctta tatcaaggct
    12301 atcttagagg cctttaacag tccttacctt gacaagcttg tcaaccaaat tgacactttg
    12361 cctgagctag agcacctgat acggtcagct atagatccag atgctcctgc tactatcaat
    12421 gaaggcaata ttatcagaac aggctttgat gaacggctgg atcattaccg aaaggtcatg
    12481 cgagaaggca ccggctggat tgctgatatt gagacaaaag aaagacaggc cagtgggata
    12541 agcaatctca aaatcgacta taacaaaaaa gatggctact attttcatgt gaccaactct
    12601 aatctaggta tggttcctga ccattttttt agaaaggcaa cattgaaaaa ttctgagcgc
    12661 tatgggacag cagagctagc taagattgaa ggacaaatgc ttgaggctag agaggagtca
    12721 tctagcctgg aatatgatat tttcatgcgt attcgtgctc aagtggagac ctacatcgat
    12781 aggctgcagc agctagcaaa agctctagca actgttgatg tcctacaaag cttagcagtg
    12841 gtcgcagaga agaatcacta tgttcgacca ttatttaatc aagagagcaa gattgcgatt
    12901 gacaatggtc ggcatgctgt tgttgaaaag gttctaggtg ttcaggagta tattccaaac
    12961 agcatttcct ttggtccaca gacaagcatt cagctcatta caggaccaaa catgagtggg
    13021 aagtctacgt atatgagaca gcttgctttg acagtcatta tggctcagat aggctcattt
    13081 gtagctgcag aatctgctag cctgccttta tttgacgcta tttttactag gattggtgca
    13141 gcagatgatt tgatctcagg ccagtctaca ttcatggttg agatgatgga ggctaatcat
    13201 gctatcaagc gagcaacccc tcattccctg attttgtttg atgagttagg gcgtggtaca
    13261 gcgacctatg atggtatggc actagcccag tctatcatcg aatacattca tgatagagtt
    13321 ggtgcaaaga ctatgtttgc gacccattat catgaattga cagagctgtc aaccaagttg
    13381 acaaagctgg ttaatgttca tgttgcgacg ttagaaaaag atggaaatgt aaccttcctg
    13441 cataagattg ccgaaggtcc tgctgataaa tcctatggga ttcatgtggc gagaatagct
    13501 ggattgccag aggatttact agccagagct gatactgtgc taaccaagct ggaagctcaa
    13561 tcacaagcaa gagagtccgt cttatcaact acagaagtaa gagagactca gcagctggct
    13621 aatcagcagc tatcactttt tacagatgat ggctcctcta gcgagattat taaaaggctt
    13681 gagagtgttg atgtgatgaa tctaactccc attcaggcca tgaccgttct ttatgagcta
    13741 aaaaagctac tgtaaaagct agtatcagat gttaaaggca cttgtaggct caccaggcca
    13801 caggtgcttt ttggtttatt gaccataaga cccttgctag ctctgatgct tggctctttt
    13861 agttttatgt tataatagtc cataagaatg cgaggaaata tatgacaaca attatcgaat
    13921 tacctgaggt tctcgccaat caaattgcag ctggtgaagt cattgaaaga ccagcaagtg
    13981 ttgttaaaga attggttgag aacgccatag atgcaaagag tagtcagatt actgttgaaa
    14041 tagaagagtc tggcttgaaa atgattcaaa tcactgacaa tggcgaaggg atgtctcacg
    14101 aggacctgcc cctgagcctg cgtcgtcatg ccacaagtaa aatcaaaagt caaagtgatt
    14161 tgttcagaat cagaacactt ggctttcgag gagaagcttt gccttcggtt gcctctatca
    14221 gtaaactaac gatcaaaaca gcaacagctg atgcagagca tgggtcaata ttagttgcta
    14281 gtggcggtaa gattgagcag ctggaagctg tctcaacacc tgttggtaca aaaatcaagg
    14341 tagaaaacct attttacaat acaccagcta gactgaaata catgaagagc ttacaagcgg
    14401 agctggctca tgttgttgat gtcgtcaatc gcttgagcct ggctcaccca gagattgctt
    14461 ttacattgat cagtgatggc aagcagctaa cacaaacctc tggggctggg gatttacgtc
    14521 aagcgcttgc tggtatctat ggcctgaata ctgctaaaaa aatgattgac atttctagtg
    14581 ctgatttaga ttttgaagtg ggaggctttg tgagtctgcc agagctgaca agagctaatc
    14641 gtaattacat tactatcctg atcaatggtc gctatattaa aaatttcttg ttaaatcgag
    14701 ccattttaga tggttatggc tctaagctga tggtgggacg ctttcctata gctgtcattg
    14761 atattcaaat tgatccttat ctggcagatg ttaatgttca cccaaccaag caggaaatta
    14821 gaatttctaa ggagcgtgaa ttaatggctc tgattagtac agctatttca gagagcctac
    14881 gagaacaaga cttgattcct gatgccttgg aaaatttagc taggtccagc acacgttcat
    14941 tttcaaagcc tgagcagacc agtttgcctt tacagcctag tcagctttat tatgatccgc
    15001 aaaaaaatga tttctttacc aaagaaacag tggtttcaga ggatagcccg cagggcttta
    15061 accatgaaac tttggttgac agtggtgtca agcaggttga caatttgcag ctggccaaga
    15121 ctgaatctga agcagctgct ccaagtgtta aatatgctag tcggccagat cctatgcttt
    15181 ctgatggtga gcacccgggt cttgatgtcc acaataagca aaaattatct cagatgcttg
    15241 atcgtttaga aaatgaagag cagtcggtct ttccagagct tgattatttt ggccaaatgc
    15301 atgggaccta cctttttgcc caaggcagag atggcttgtt tatcattgat cagcacgcag
    15361 ctcaggagcg cgtcaagtat gagtattatc gtgacaagat tggtgaggtt gacaatagcc
    15421 tacaacaatt gctggtgcct tatctgtttg agttttccgg atcagatttt attaatcttc
    15481 aggaaaaaat gtcgcttttg aacgaggttg gtatttattt agagccttat ggcaatcata
    15541 cctttatcct tagggagcac cctatttgga tgaaggaggc agagattgaa tctggtgttt
    15601 atgaaatgtg tgacatgctg ctgttgacaa atgaagtatc catcaaaact tatcgtgctg
    15661 agctagcgat tatgatgagc tgtaaacgtt ccatcaaggc aaaccatagc ttagatgatt
    15721 attcagcaag acagctgctt ttacagcttg ctcaatgtaa aaacccctat aactgcccac
    15781 atggtagacc tgttttgatt aacttcagca aggcggacat ggaaaaaatg ttccgtcgta
    15841 tccaagaaaa tcacaccagc ttgagagaat tgggcaaata ctagagagga tagcatgcga
    15901 gaatttttcc agttacctaa gcaaatacaa attcggcaat ttgtgcgctt tattaccatt
    15961 acgcttggca gtagtatctt tccttttatg gcgatgtact atacaagcta ctttggcgcc
    16021 ttttggacag gcatactaat gatggtgact agctttacag gctttattgg gaccttatat
    16081 ggaggtcatt tgtcagatgc tattggtcgt aagaaggtaa ttatgcttgg ttcagttgcg
    16141 agcaccttag gctggctgct gaccattttg gccaatgttc caaagacggt tcttccttgg
    16201 ttgacctttg tgggaatttt gctggttgag cttgcttcca gcttttacgc tcctgcctat
    16261 gaggctatgc tgattgattt aacagatgat agcaatcgtc gctttgttta taccattaat
    16321 tactggttta ttaatatagc cattatgctt ggtgcaggta tttcaggact tttttatgat
    16381 cggtatttct tagaactgtt gattgcttta ctgattatta atatcgtctg ctttggtatt
    16441 gcctatcgtt attttggtga aacgaggcct gagcattacc gctttgagca tggtattggt
    16501 attctagcag gttttgctaa ctaccggcaa gtctttaagg atcgcgcttt tgtgttattt
    16561 actataggga cgattttatt tagcagtatt tggttgcaga tggacaatta cgttccggtt
    16621 caccttaagc tgtattttga agagactgat gtgctcggta ttcatctgac tagctcaaaa
    16681 atgctgtcac tgatggtctt taccaatacc ttgctgattg tgctgttgat gacagttatt
    16741 aatcgcttga cagcaaggtg gagattatta ccacagctgg tgatcggatc ggttattttt
    16801 gcctttggta tgctgttgtc atttacattt actggctttt ttgctatttg gtgttcagtt
    16861 gtggtgttta ccattggtga aatgctaaat gtccctgcca atcaagtgtt aagagcagaa
    16921 atgatggatc agtctaaaat tggctcctac acaggctttg tctcgatggc ccagcctttg
    16981 ggagctattc tagcaggttt gctggtttct cttagtcatt ttacaggaca ggctggtgtt
    17041 cagctagcat ttgttttgat tgcctgtgtg gggctttatg tgattgtttt atctgcgaaa
    17101 atgaagaaaa aggtgtagta tgtacgatta tattaaaggt cagctaacaa aaattactgc
    17161 aaagtatatt gtggtagaag caaatggttt aggctatatg ataactgttg ccaatcctta
    17221 tagctttaca gactgtgtca accagcaggt aacgatctat cttcatcagg tgatcagaga
    17281 agatgctcag ctgctgtttg gttttcacag tgaggaagaa aaggacgttt ttttgaagct
    17341 gatttcggta tcaggtatcg gaccgacgac tgccctagct attgtagctg tagatgataa
    17401 tagaggactc gtcaatgcca ttgataatag tgatattaca tatttgatga ggttccctaa
    17461 aatcggaaaa aaaacagctc agcaaatggt gcttgattta gcaggtaagt tcgttgaagc
    17521 acctaaggag gaaagcagca agccccctaa agccaagcaa caggggaatg aacagcttga
    17581 tgaggctgtc gaagccctat tagcccttgg atataaggcg acagagctaa agaaaattcg
    17641 agccttcttt gagggaacaa gtgagacagc tgagcagtat atcaaatcag ctctgaaaat
    17701 gctaatgaaa ggctaggagc ttcatatgaa acgttgcgca tgggtaccac aagataataa
    17761 gctttattgt gattaccatg acttggagtg gggaaggcct gtctatgatg atcgcgctct
    17821 ttttgagctg ctttgtcttg aaagctatca gtcaggctta tcttggttaa ctgttttgaa
    17881 aaaacgtcca gccttcagaa gtgtttttca tcattatgat atctcagctg tggcaagctt
    17941 tagtgagcag gaaatggctg ctgccctgca aaatgcagca attatccgac acaagccaaa
    18001 gctaatagcc actgtcaaca atgcagcggc agtccagcgc atccaacaag agtatggtag
    18061 cttttccagc tatctttgga actttgtagg aggtcagcca attgacaggc ttgtcaacga
    18121 tgacaaccca gcgcccgctc aaacagccct atctctcaag ctatctaagg acttgaaaaa
    18181 acgtggcttt aagtggctag gaccaacaac tgtttattcc tttatgcagg cagcaggatt
    18241 ggtcaatgac catgaagaga actgtgagtt taggtagaat taatcgcctc tttggagtga
    18301 tgtttcatga gcctatcaaa gagagcttga taaaaacagc ccaatcttga ttgcttatag
    18361 gatgatgtat aagagctatg tttttgctcc gtactttaag gatagatgat gaatcccctt
    18421 atttaccctg tagcgaatgt tgtaagcttc taatgggttt aaggttttag cctgttactg
    18481 ctattgccag taagctacag tttgatcagg tagttatatt ggattgcctc aacgattgtg
    18541 ttgctgctgg ctggtgcttc tttctataac ttattttggt gcatgtgatt gtggctctaa
    18601 aagttataac agagtatcgg tacgattggt gttacccctt ggtttctatt tttttcttat
    18661 cagccagtct ggcatttaca gcctataata aaagctaccg cttaaaaatt tcttagcggt
    18721 agttttttag ttcatgttgc aaggtttcta gaagttcagt ttcttctgtc aactgtagta
    18781 attgtaagcc tttattaatt aggtgatcat cattacgaca aataccgaga cgaacttggg
    18841 aaaaacctaa gctatcatag cgtttaagct gtctagctaa tttgattgtt agtaaggtaa
    18901 tttcttcgca ctcctttttg aggttgtgat agaggtaaat ggttgaaaga ttggttagta
    18961 aagcatattc agatgatttg atattgcggt aatctttata ttttgctagg ctatctagga
    19021 ttttttgact gatgttttca attatttcga taggaaagtg aaaaagaatg gtatgtagta
    19081 attgtaaatc tttctcatac caagtatctt gttttacgag ggaattccag attttataag
    19141 ctagctcttg taaatcttga ttgtttttaa cgcctttttt cctaagactt atcatgactt
    19201 cgacactatc taaaatataa gaaatgggaa tatcattttt atttttaagg taattgaagc
    19261 atttttgacg taatttttct aattcagtaa tatttacagc tgatacctga ttataaaatt
    19321 ggtttaaaat gtcctgcctt gtgctaggat gataagtgtt gcagacatat ctaaactctt
    19381 ccagtgtcat attgagttgg tttaataaaa aaatcattgt atcaaattta ggaatgactt
    19441 gtccgctttc aatacgagct agtgtagaac gagctaaaaa gtctccacag atcttttctt
    19501 gtgttaatcc tttagatttt cgtatagctt gataaatttt accgtaatcc caacgcataa
    19561 aacacctcta aaatgttact aaatgctaca aaaaaataaa atctacaata gtattttata
    19621 atagcattta gaaagagtaa aggaggaaaa tttatgagga gacatctaaa ggttgtatta
    19681 ttacttgcag cactattggc atttattgta aatgagggta attttccatg gtggccttgg
    19741 ggaccatagt acttaactga ttactgttat gttgttgcca ttagactatc tagattaatc
    19801 aaagagtaaa atacaagtag cttagtgaaa gacattttaa gaggagaaaa gcatatgaag
    19861 aaacgtttag catttatatt agttgctttt ggtattttgg gatttagttt aggaaatgaa
    19921 gttttagctg cagatactgc acctgcaagt gcaactatgg caacagatag tgatgtgagt
    19981 ttttacaatg gagaactgtt gaaaaaatat ttggtccaaa gtggtgatag attgtatttt
    20041 gattatgaca aagctattca agataaagtt tctgatggtg taatagatat gggattcctt
    20101 gttgagacaa ttagtgagga ctattcacaa caaacgttta cctctcgaaa gtatttcaag
    20161 gcaggatggc agctttatgg taattattgt ggacctggcc ataacggaaa tcattttact
    20221 ttacctgtta ttgatgtttt agatcaaggc tgtcaaaatc atgacagttg ttatcgatgg
    20281 ggagctggga ttggtgcaaa ttgtgaatgc aatcgtcagt tagtaaatta cattaaagta
    20341 tatcgacggt ggatgccagc tcatgccttg ggggttgctg atgctattag agtatatttt
    20401 gaaacggtag gtgctattgg atgttaacct taaaaaatat tatcaatcga tactacatgt
    20461 attatgtatt ccttattgtt gtgatctgga ttgggatgtt ttttgtacga tgggatacta
    20521 ctgtggctgg tgtattactc tatccactga ttatgaagca ggtatttatc gtactaggag
    20581 tagttgcgat gataatggcc attatttcta gaaaaattgt tcttggaatt tttggtttac
    20641 tatgctgtgc tgctttttgg attaatcttt tcttagcttt ctatctatta cctggacttt
    20701 tgggaaatta gcgattaaac tgtttttgat gttttgaaga tgagaaacag attgtttttc
    20761 tgtaaggctt cctgttactt ctcaaatgct ttggagtatc tctttatcat ttgttcactg
    20821 ttgacaacgt taaaaagatt attccaaaca tgggaattgc tgcttcaggg tattccttgt
    20881 taatattgga ttgattagtt gttatttatg caaaatcctt agagcattgc tttctcattc
    20941 ttggttcatt tgaataaaat gtaactaaaa aaactttgta atcaattcaa attgtcacaa
    21001 gtataaaagt aaaaaagcga ctttgttagt gatctgatat tcggaagtcc tatcattgct
    21061 cgctttttgt tttttgaggt tgatttttat tccgaaattg ttgtgaataa gtgcaatttt
    21121 aagctaagaa ttacctaaaa tcttttgaag attactgctt agcttctaat acctatttat
    21181 cggtgtgttg ataattggag agatagcggg attgtcatat gaaataaatt ttagaaaatt
    21241 taaacaagtt attctgatta ttattatttc aacataagtc tttatttgat tatcattgaa
    21301 aaccattaat tcatctaaaa ttatttcaat gcttcatgga tgattctttt tttgttaaaa
    21361 tgagattgaa tgtcgaatag ataagtaggt gggaaaatga aagctgaact cattgcggtg
    21421 ggaaccgaga ttctgactgg tcagattgtg aataccaatg ctcaattttt atcagaaaaa
    21481 atggcggagc ttggtattga tgtttatttt caaacagctg taggagataa tgaagagcgt
    21541 ttgctttctg ttattgatat tgctagccag cgaagtgatt tagtgatttt atgtggtggt
    21601 cttggtccaa cagatgatga tctaacgaag cagaccttag ctaagtatct gggaaaagct
    21661 ttggtctttg atgagcaggc aggtcaaaaa ttagatgctt tttttgcaca tcgtaagcag
    21721 gctgctagga caccaaataa ccaacgtcag gcgcagctga ttgaaggctc tattgctttg
    21781 caaaatcaaa caggacttgc agtaggtggg ttaataactg tagatagggt aacctatgtt
    21841 gtcttaccag ggcctccaag tgagctaaag cctatggtaa aaaatgagct ggtgcccctt
    21901 ctttcagcta gtcatgccag tctatattca agagtgctgc gtttttttgg cattggtgaa
    21961 agtcaactgg tgactgctct ggaggatttg attaagcatc aaacagatcc tactattgct
    22021 ccttatgcaa agaccggcga ggtaacactg cgactatcca caaaggctga caaccaagca
    22081 ttagctgatg aaaggctgaa tcgactagag gcgcagctct tatccataag aactgtagat
    22141 aatcaaccct tacggcgttt gctttatggc tatggggagg ataattcctt ggcgcgtgag
    22201 acctttgagc tattgaagcg aagtggtaag acgataacag cagctgaaag cttaacagca
    22261 ggactgtttc aagctcagtt aactgatttt gcgggagctt cacaggtgtt taacggtggc
    22321 tttatcacct acagcattga agaaaaagca agaatgcttg gcattccatt gggtgagcta
    22381 caaaggcatg gtgttgtgag ctcttttaca gctgagcaaa tggctgcaca ggcacgctgc
    22441 ttgaccaatt cagatatcgg tattggtcta acaggtgttg ctggtccaga ggcactcgag
    22501 ggacagccag caggaacagt tttcattggc cttgccacta agaataaggt agaatctctt
    22561 aaagttgtta taggaggccg tagccgtttg gacgtgcggt atattgctgc cctatatgct
    22621 tttaatatgg ttcgtaaaac tttattaaaa tcagagaatt tgctataatt aggatagtgt
    22681 attttaggaa attagtaact agacagatgt gaggttatgc tgtttattgc ttgctagtca
    22741 gcctaaatag aggagaaaat attggcaaaa aaagttaaaa aaaatgaaga aatcaccaaa
    22801 aaatttggtg atgaacgtcg taaagcactt gatgatgcgt taaagaacat cgaaaaagat
    22861 tttggtaagg gtgcggttat gcgccttggt gagcgtgcag agcaaaaggt tcaggtgatg
    22921 agttcaggca gtcttgcttt agacattgcg cttggagcag gtggctatcc taaagggcgt
    22981 attattgaaa tctatggacc agagtcttct ggtaaaacaa cagttgccct gcatgcagta
    23041 gcgcaggctc aaaaagaagg tggtattgca gccttcattg atgcggagca tgccttggac
    23101 cctgcttatg ctgcggcgct gggtgttaat attgatgagc tgcttttgtc acagccggat
    23161 tctggtgagc aaggacttga gatagcaggt aaactgattg attctggtgc tgttgatttg
    23221 gttgttgtcg actctgttgc agctctagtg cctcgtgctg agattgatgg tgatattggt
    23281 gataaccatg ttggcttgca ggctcgtatg atgagtcagg cgatgcgtaa gctttcagcc
    23341 tcaatcaata aaaccaagac aattgcgatc tttattaacc agctgcgtga aaaggtaggg
    23401 gttatgtttg gtaatccaga gacgacacca ggtggtcgtg ctttgaaatt ctatgcctct
    23461 gtccgtctgg atgttcgtgg aacaacacaa ataaaaggaa ctggagatca aaaagacagt
    23521 agtattggta aggaaaccaa gattaaggtt gttaagaata aggttgctcc gccatttaag
    23581 gtggctgagg ttgaaatcat gtatggagaa ggcatctcac gtacaggtga gctgattaaa
    23641 attgcttcag atttagacat tattcaaaag gctggtgctt ggttctctta taacggtgaa
    23701 aaaattggtc agggctctga aaatgccaag agatatttgg ctgatcaccc agagctgttt
    23761 gatgagattg accataaggt gcgtgttaaa tttggcttgc ttgaagatac tgaggaaagt
    23821 gcagctgcag atacagttgc agccaaagca gatgagttgg ttttagagct agacgatgcc
    23881 attgaaattg aggattagtg cttagtatta gattttcaga taaaggtgct aaaaagggct
    23941 taacagcgat cgtcaagccc tttttagctt gtgtttaatc aagctctgta ttggtctgct
    24001 caggagctag gctgtacgct tggataattt gttagctgag tttatgtttt ctttagggat
    24061 taactgttaa gctataaaag ccctagaaaa aagggacttc ctacagacaa gatagtggca
    24121 tagtaagctt gcttgcaact agctcaatat aggattttgg ccttggttaa agggatcata
    24181 aaagaaaact aaaaaatagg tccaaagacc gatattgatt agaaaaaaac tatgctacaa
    24241 tagaggtatc acgagataga aagtgagaac aacatgataa aaatttacac gatttcaagt
    24301 tgtacgagct gtaaaaaggc taaaacctgg ctgaatgccc ataagctccc atataaagaa
    24361 cagaatttag gaaaagaacc tctttcaaga gaagaaattt tagctatttt atcaaagact
    24421 gaaaacggtg tggagagtat tgtctcttct aaaaatcgtt atgccaaagc cttaaattgt
    24481 gatattgacg agttaagcgt aaatgaggtt attgatttga ttcaggataa tccccgtatt
    24541 ttaaaaagtc cgattcttat cgatgacaag cgtcttcagg tgggctacaa ggaagacgat
    24601 attcgtgcct ttttacctcg ttctattcgt aatattgaaa atgcagaggc gcgtttacgc
    24661 gctgccttat aaaaagctct gtcagagctt tttttaatat cctaacaaat ctgaattctt
    24721 gtttattcaa taaaaataag ctataataga gcgtagcact taaagttaga aagaaggtgt
    24781 aagtatggga tttacagatg aaacagtccg ctttaattta gacgatggtg ataaaaagca
    24841 gattagcgaa acgctgacgg cagtttatca ttcactagat gaaaaaggct acaatccgat
    24901 taatcaaatt gtaggttatg tactaagcgg ggacccagct tatgttcctc gttacaatga
    24961 tgctcgcaac caaattcgta aatatgagcg cgatgagatc gtagaagagc ttgttcgcta
    25021 ttatttgcaa ggaaatggaa tagatattag atgagaataa tgggacttga tgtcggttct
    25081 aagaccgtcg gtgtggcaat tagtgatcca cttggtttta ctgcccaagg actagagatt
    25141 attaggatca atgaagataa acaggatttt ggctttgata gattagctga gcttgttaag
    25201 caatatcagg ttgatcgatt tgtcattggc ttgccaaaga atatgaataa cactagtggc
    25261 ccacgtgttg aagcaagtaa ggcttatgga gataagattg aggagctctt tcacattccg
    25321 gtttcttatc aagatgagcg cttgacaact gttgaggcag agcgtatgtt gattgagcag
    25381 gcagacatca gtcgtggtaa acgtaaaaaa gtaatcgata agctggctgc gcagctgatt
    25441 ttacagaatt atttagattg taactattaa ggagaacaga tgacacataa tcatgatcac
    25501 gaacacgaag tcattacact tgtcgatgag caaggaaatg aagcattgtt tgaaatttta
    25561 ttaaccatcg atggacgtga agaattcggt aaaaactatg ttttactagt tcctgctggt
    25621 tcgcaagagg atgaatcagg agaggttgag attcaggcct attcatttac agaaaatgaa
    25681 gacggaacag agggtgattt acagccaatt ccagaggatt cagacgctga gtgggatatg
    25741 attgaggaag tctttaatag cttcttagac gaagagtaac aacctgaggc attagcttta
    25801 aaataataaa tagcctagaa tcttggtgct agcagcatgg gttttaggct atttttatgg
    25861 tttatcagac agtaggagtg atagctattt ctatgacctc taaatagcct actgttaaga
    25921 gtgtttttag ggtcttgtag atgttgcaat agcctgtaat ttcgttgaag ttacttgctg
    25981 ttgtcttttt tagtttaagc cttaacaaag cttataggaa atgactcaac ttagcacagc
    26041 ataagccgct tattttgata agtaaagaaa tagccaatag ctacttttag cttaaagctg
    26101 atcattacca gtacccttag cttttctggg tattatttcg aataatctta atgggggtga
    26161 ttttatcaaa agactcagtc aagaagaaaa aagctttcta aagcattata ggctaaagac
    26221 actgcaccgc tttaaagagc tgctgactta tgccagcatt tgtcataaat tgactaaata
    26281 atagattttg ctatacttgt aatatgacat gtcaaggaga aacacattga gtcaattaca
    26341 tcaagaagtt atgctggaaa aggtcaatta tttggtgaaa gaccacccat cgtcacatac
    26401 gactaagtat gacatgaagg tccctagttt atataaattt tatatctttt tctttagcat
    26461 catagcgagc ttgcttacgg ttgcggttcc tttttttgca gatactgcaa atagcgttca
    26521 gtcacaaaat ttatacatcg gaatgatgtt gactaaaggt cagattccat atagtgactt
    26581 gtttacaaca ggaggctttc tgttttttgt gctcatagct ttgagctatc acttgggaac
    26641 aacggtatgg ttggtacttg ttcaagcgct gtgcttttat ttgacaggtg tttatttcta
    26701 taaattaatc cattatgtga caggtattca gaaggtggct ttaggtttta cagctatcta
    26761 ttacctattg tctattagtc ttggatttgg tggcttatat gcgatccagc ttgccctgcc
    26821 ttttgtcttg gtatcgcttt ggtttttaac caagtatttt gctggcttgg taaaggacga
    26881 ggcctttatt ctctttggct ttgcagcggc aatagccatg ctaattgagc ctaggacgct
    26941 tcttttttgg ctgcttgcct gcattgcgat tattgcttat aatgtgtctc aaaagcattt
    27001 cgctcgaggc ttttatcagc tgttagcagc tatttttgga atgcttttgg tgttttatac
    27061 agcaggctat tttatcctca atttacagat tttgagtcct tatttggagc aggcgcttgt
    27121 ttatccgttt agttattttg tgacaggtga tttatcgctg attctcggtt taacagtcca
    27181 attaggactt gttcttggct tgggactgtt aacggggctg ctgacgttta tgaagcagcc
    27241 taagctagag tctgatcttg ctatgaaatg gctactagtc tttgttgtgt ttagctatgc
    27301 tggtattgcg gctatatcgc atgattttca tacttatcac ctactgcctt tactgcctta
    27361 tgctttgatc ttgctatcaa gctctgttgg ccgacaatat gaggcaggac ttaggatggt
    27421 tagtcatcgt cgtcgtaagg ggaaaaatgg tgcgagacgg gttattgcta tttatctaaa
    27481 taagcatttc tacgtgccag caatcataat gctaggagcg gtttttggca cagcttatca
    27541 gtatgtgacc agctctgcta ttaatcaaga gcgttctcag attgctcact atctaagaca
    27601 gaggctaacg gaggaccaac ccatctatgt atgggacgat acgtcaaaaa tttacctgga
    27661 aacgcaggcc aagtcagctt cacagtttgc ctcacccttt gttaatctga aaaaagagag
    27721 tcatcaacag atgttagagg atgagctact acagaataag gcagtctata ttgtggtcaa
    27781 caagcaaaaa gcattaccaa aggcagtcaa gaaaatagtg acagctaatt ataaaattga
    27841 cagaaagatt gatgttaagg gctttagcct atatcagaaa aaataaataa aatcaatata
    27901 ttgtgttggt ataaaaaaac ttaacacaat atattgattt ttttgtgtgg cgtgatataa
    27961 tagtcgagta aggagatagg acatgataac attagaaaaa gacaaagtta ttgttcagcc
    28021 agctattaag gttattaaaa gagatggacg cttggttaat tttgatgcaa caaagatcta
    28081 cagtgcgctg ttaaaagcaa gcatgaaggt aacacgcatg tcaccgctcg ttgaagcaaa
    28141 gctagaagct atttctgaac gcgttattgc agaaattatc gagcgatttc ctacaaatat
    28201 taaaatttat gaaattcaaa atattgttga gcatgagcta ttagccgcta atgaatatgc
    28261 tattgctaag gaatacatca attatagaac ccagcgtgac tttgcccgct cgcaggcgac
    28321 agatattaat ttttctattg ataagctcat tcacaaggat cagacagtag tcaatgagaa
    28381 tgccaataag gatagtgatg ttttcaatac ccagcgcgat ttgacagctg ggattgttgg
    28441 taagtctatc ggtttgaagc tgctgccagc gcatgttgct aatgcccacc aaaaaggtga
    28501 tattcactac catgatttag attatagtcc ttatacgcca atgacaaact gttgtttgat
    28561 tgattttaag ggaatgctgg caaatggctt taaaattggg aacgctgagg ttgaaagtcc
    28621 taagtctatt caaacagcaa cagctcaaat ttcacaaatc attgctaatg tggcctccag
    28681 tcagtacggt ggctgtacag ccgatcgtat tgatgagttt ttggcaccat atgctgagct
    28741 aaatttcaaa aagcatatgg ctgacgctga aaaatgggtt attgaggagc tgcgggaaag
    28801 ttacgccttt gaaaaaacaa aaaaagacat ttatgatgcc atgcagtctc tagagtatga
    28861 gatcaacacg ttatttacct caaacggtca gacccccttt acctcattgg gatttggtct
    28921 agggacctct tggtttgagc gtgagattca aaaggctatt ttaacgatta gaattaatgg
    28981 cttaggcagc gagcaccgta cggcaatctt ccctaagctc atctttacgg tcaagcgtgg
    29041 gctcaattta gagccagact caccaaacta tgatattaag accttagcct tggaatgtgc
    29101 cacaaagcgc atgtatccag atatgttatc ttatgataag attattgagc tgacaggatc
    29161 ctttaagtca ccaatgggct gtcgctcttt ccttcaaggc tggaaggatg aacaggggca
    29221 agatgttacc tcagggcgta tgaaccttgg ggttgtaacc atgaatttac ctcgtattgc
    29281 tatggaatca aatggcgata tggataaatt ctgggagctg tttaacgaac gattacacat
    29341 ttgtaaggac gctcttgttt atcgtgtaga gcgcgttaag gaggcaacgc cagccaatgc
    29401 tcctattctt taccaatatg gagcctttgg caagcggcta gctaagactg gcaatgttga
    29461 tgagctcttt aacaatcgcc gcgcaactgt atcattgggt tacattggct tatatgaggt
    29521 agcaaccgta ttttacggtg ggcaatggga gcacaaccaa gaggccaaag actttacaat
    29581 cactattgtt aaggaaatga aaaaggcttg cgagacttgg tcagatgaat atggctatca
    29641 tttctctgtt tactcaacac catcagaaag cttgacagat cgtttttgcc gcctagatac
    29701 tgacaaattt ggcgttgttg ctgatattac agataaagaa tactatacta attcattcca
    29761 ctatgatgtt cgtaaaaatc caacaccttt tgagaagcta gattttgaaa aggcttatcc
    29821 agcagccggt gcttcaggtg gctttatcca ttactgtgag taccctgttt tgcagcaaaa
    29881 tcccaaggcc ttggaagctg tttgggacta tgcttatgat cgtgtgggct acctaggcac
    29941 aaatacgcca attgataagt gctatgaatg ccattttgag ggagatttca ccccaacaga
    30001 gcgaggcttt acttgtccaa attgtggaaa caatgaccct aagacagtag atgtggttaa
    30061 aagaacctgt ggttatttag gaaaccctca ggctcgtcca atggtcaatg gtcgtcataa
    30121 ggaaatctct gctcgtgtca agcacatgaa cggatcaacc atcaagtatc cggggatata
    30181 agccttggag aataatctca ttacacctat atcattgtaa aggattgctt catgcaagca
    30241 gtcctttagt tatcaagaca ggtctgtaac aaagaaaggg agaaacatgg gaaaatacca
    30301 gttagattat aagggaatgc agcaagtaga gaggtttcat gagaaacatt ctgttgcaaa
    30361 aacagacaaa aagtctcgag tacagcagct tagagcacaa tttttagaaa aagcaaagca
    30421 atcaaagaaa taatggcaca ctcagtaaag gcggtgaaga atgctagata ttggaattgt
    30481 tgggttaggc gctatttcac aaaaggccta tttaccctat atgcgtcaat taagaggaat
    30541 caattggcat ttatctacta gaaatgcgtt agtccgccag gaggtgggtc agctttttgg
    30601 ttgcgcaagg ctttacagca ctgtcaatga gttacttgag gctaagttag atggtgtgtt
    30661 tatccatgca gccactaagg ctcatttaga gctggctagt ttgtttttac aaaaaggaat
    30721 tccagtttac atggataagc ctttgacgga ggatttcttt agcacgcagg ctctttatca
    30781 attagcagat aagcacaata cctttttgat ggcagacttt aatagacgct ttgcacctgg
    30841 tgtcaagaag ttgtcaaccc tgtcaaccaa acgtaaagtt gttgttgaga aaaatgatat
    30901 taatagacca ggtgacaaac agtttaagct ttttgacttc tttatacacc ctttagatac
    30961 agctttattt ttagttgata ggaggcttgt tgcaggctat tttcattatc agctgactga
    31021 taatgatttg ctaagtcagg ttagtgtaac cttaaggaca gaacagacta ttatttcagc
    31081 agctatgaat ctacagtcag gtagcaggcg tgaggtgatg gaggttcaga cacctaaaga
    31141 gacctatcac ctagaaaatc tagagacctt gcgagcttat cgaggggttg atcaagagat
    31201 caagggattt agtgcttggg atactacctt atctaaacga ggctttgagg ctattgtgga
    31261 ttctttttta caggctgtca aggatggtgt taaccctgtc aagccagaga caagtctgtt
    31321 gagtcactgg atttgtcacc aaatttgtca atctcatgaa gctgatggca tattagatgt
    31381 ttctcttccc ttataaagga gtgataatat gaagctacga agacctaaaa agcaagatga
    31441 agcgtctgtt ttagaaatga tggcagagtt tgaagactat cagtctcctc atgatggtgg
    31501 tttttggaac gctgagcatt ttgattatga aaaatggttg gaatctaatg ctctgatgga
    31561 ggctggctta gctatccctg agaattgggt gcctgccata cagctcgttg cctttgctga
    31621 tcaacaggct attggatttg tcaatgtacg cttgagatta aacgaacagc tactggtaaa
    31681 aggtgggcat attggttatt ctgttagacc tagccagcgt ggaaagggct atgcaaagct
    31741 gatgctaaag gaagccttgc agcttgctcg tcaaaagggc attcgtgagg ttttagtgac
    31801 ttgtcattgc agcaatagtg ctagtcggtc tgttatttta gctaatggtg gtcagctgaa
    31861 ggattgcaat aagggtattg aacgctattg gataaaagca taagaggcaa taatgaagga
    31921 aaactgttgg aattctccca aaccaaaaga atggacatca gaggcattaa gccaaggacg
    31981 cgttattgat tataaggcat ttaattttgt agatggggag ggagtgcgaa actcacttta
    32041 tgtttcaggc tgcatgttcc attgtaaggg ctgctataac gcagcaacct ggtcttttaa
    32101 ggcgggtatt ccttatacga aagagcttga ggagcaaatt atgactgatc ttgcaaagcc
    32161 ctatgttcaa ggtttgacac ttttgggcgg tgagcccttt ttgaatacgg gaatattgat
    32221 tcctttgatt aagcgtatca gaaaagagct gccagaaaag gatatttggt cttggacagg
    32281 ctatacctgg gaggaaatga tggaagaaac ccaggataag ctagagctgt taagcatgat
    32341 tgatatttta gttgatggcc gctttgatat caccaaaaag aatctgatgc tgcaatttcg
    32401 tggatccagt aatcagcgta tcatcgatgt taaaaagtca ctggctgctg gagaggtggt
    32461 tatttgggat aagctaaatg atggtgatca gtcctttgag caaatgagcc gcgatgattt
    32521 gatttagtag agacttatca acatcactag acttgaaagc taataatgaa agcatgattt
    32581 taggctcctg tggtcttgct taaccaatct aataaggggt tttccccaca ttatcctcat
    32641 acttatccac aggttgtgaa taacctgttg gtttgtggat aaaaaagaga attaaggggt
    32701 tctttaattc tctaggcctg aaaaagggtt ctttttgatg ttttttctta aaagaaagag
    32761 aggcaagtga cctctcttga aatagtatac ttaggcttta agcctagctt tcaatatctc
    32821 tgaatgtctg attttcttag gagtcaggca ttttttaatg gcgatgggaa gtacggcttg
    32881 tgggtcgctt tgtgtgctaa gaggctttct gagctgctat atgtcaatga ttggtgatgt
    32941 gacagctgag gcttgttcac attctgaaag cactgatgtt tttcctagct ttcttttttg
    33001 atgtagtagt aattagtttc ggttgatagc tcctcattat agcaaaagcc agcaaagctc
    33061 agctgcttaa gtgcttcctt ggtttggaca ttgttttcta gacaggctgt tagaaaggct
    33121 cctcgagctt tttttgaaat ggttgaatgc gtcttgagct gtcctgatct ttcctccata
    33181 aatttgggac ttatccacag tttttgatat tcctttgaaa aaacatctct aaactcgttg
    33241 gataacagag aaatgatttg cttgtgatct ttagcaaact gatcgtagat agggcgccaa
    33301 taatgcttaa ggctttgccc attgatggtt actttagtgt gaaaatcatg ccggtgctct
    33361 gcgattttct catcagtagg gataatgcca taaaaagacg aggtaatgta gacctgcttt
    33421 gagaggtagt cttgctggtc tttagagaga ttgtcgcgct tgagatgacg gtacatgagc
    33481 ccattaaaga gctgataagc aggataagca gaactctgcc cttgagctat ggcctttagt
    33541 ctcttggctt ccttgcttgc tgcttctata cggatgctgt aggcccttgc tagctcctct
    33601 agggatagtt cagccatagc ctctaatatg ggcaggcttt tttggggaag ctgatgtgga
    33661 tagcaaggtg gaactggttt catttcttta gctgttggaa ttaaaaaagt taacataagt
    33721 ttattgtagt aaaggcggca accttctgtc aagagtggga tacatttggt ggttatgtca
    33781 tatgaaacta atttttatat tttttacatt ttgattagtt tttaaaaata tagtgattta
    33841 gtgttgcata acctctctaa gtatgttaat atatacttaa gtctgtttga taaacagaag
    33901 ctcaggtcaa gtgagtgttc cacttacaat aacgcagttg atgatgggga gactcagact
    33961 cagactcaga ctcagactca gagtcaagga aaagaaatat agtcttgtag gattacctac
    34021 agggcttttt tctattttga attgagagat caatataagg tgatgtgctg ttttttatta
    34081 ccttaaacat ttggatattg gctattgaca aaaagtgtaa aggaaactat actatatgtg
    34141 taaagttaac ttgacatatt ggaggaacca tggaaaatcg gatacaagaa ctccgtaagt
    34201 cacgagggat tagtcaagct gatttggcag atatgatgtg tgtcactagg caaaccatta
    34261 tctccttaga gaaaggacgc tataatgcgt cattagagct ggcctataaa ttagcgacat
    34321 ttttcaatct gactatagaa gacgttttct tgtttgaaga gaagggagaa tgagatgata
    34381 tttagtgatt taagcgtcct gctgactcaa aaaagccagc tagcctatgc caaaaggctg
    34441 aagtatatgg gctttttcgc tctctgttta ggcggtttgt ttttgttgct ggcctttgac
    34501 gtgagactga cgagctttgc tcagggaatg ctggtagggc ttggtagtgg tagcttatta
    34561 ttaggtgttc gtgctttttc agattgcctt taatcctcaa aggctgagag cctcttatat
    34621 taaggcttat gatgagcgtc atcaggtagt tatcaagcta gctgctgtat caaccttaat
    34681 cttattagtg gtgttgatta ttggctgttt gtgcttgaat gttttttgga gtttggtttt
    34741 tggctttaga gtatttttag agatttgtct gtatacgatc ttgcttggtt ttttaggcat
    34801 caagctattg ttagagcata tgatttagga ggcttcaatg gaaacaaaac attcagcagt
    34861 aaaggtcatc atcagtaaat taaaatggtt tggcttagct cttcttgtgt ttatgcttga
    34921 gcaggctcca acatttttga taacaaaaga acagccaatg tggcagacac ttcttcttgt
    34981 ggtcattttt cttttgatta gtggaggtac ttattaccta gctgtgaagc ttcacattgt
    35041 gggagatcaa gctattccta agaatgacta tcgggcactt tggattggtt tgggagtggt
    35101 agctgtcttt gttgtcaaga tgattggtgg tattctgttg tttttggagc atggtccggg
    35161 agccaatacg gtcaatcaag ctgccttaga acaggcaggc ttatctccga ttcttatggt
    35221 tacgctagtt gctattgtgg caccaattgt ggaagaaatt gcttttcgag ggctgcttta
    35281 tgggaagctc tttggtgcag agtcttatct gggcttgatt tttagcagta tcatgtttgg
    35341 cttgattcat gtgccaacag attttggcag ttggtttatc tatggcggta tggggctggt
    35401 gttaggcttt gttttccata aaacaaagaa ggtcgaatac acgatattga ttcatttttt
    35461 gaataatgca ctagctgttc ttatcatgct tttgctgcct tatcttcagt agtactgctt
    35521 gagtaatgaa gggggtaatg aatgaaaaat gatcgttgga ttgacaaaaa atatcaacgt
    35581 tgggagaaag tgtataagag acttggtcat tctttactga caatcggtgt gttggtaggg
    35641 acttatggga tttttttgat tattcaaggg aatcatcaaa cgggctttct cctttttatc
    35701 ctggggccta tactattgat tgcgtcatgt ctttgctatt atgtgtttac agagccaacg
    35761 tctttacgag aatatctgat taatagctat gatgagcgta accgagctat tcgtcagaaa
    35821 gcacaggcct actgcttttg tctatttgct tttctctttt tgatgcttgc gatattcttt
    35881 ccaaatatga cgatcaagga gctttttggg tataatcttc cgttgattgt tttcaatctg
    35941 tatgtcatga ttagagcctg ggttagtaaa cacatgtagg tcatgttaac acaaaggagt
    36001 ctagagcaag ggctttgaat gaaactattt ttctaaaaac gcaaaaaatc gcgtgcagta
    36061 acagattagg ccatgttact gcatgcgatt ttgttgtttc aaacgtgagc tcagaatgac
    36121 atatcctttt tagaaagaat aggtatttag ggctgtcttg agctagtctt aggtaatgag
    36181 cttggagctc attggtgatg gttaggatag gtctttagct tttttgatcg ttgtgtcaat
    36241 ggcagagcag acagaatgtg tcaggcctgt tttttcaaga tccatcaagc ctgcaatggt
    36301 tgtgccgccg ggactgcaga tcttatcaat caaatcatgg ggactatctg tgctgactag
    36361 caggttcttg gcgctagcta ggacagtttg actaacgata ctaagggcct tgtctttagg
    36421 cagtccattt ttgactccgg cctttgccat agcttcgatg aaaaggtaaa gataagcagg
    36481 acttgaccct gctagagcag taaaggtatc aaaatccttt tcagctattt caaaggttgt
    36541 tccaaagctg ttggttagct ctttagcagt agctaataaa tcagcagtta ctaagtcatt
    36601 accagtcaaa gcagtggtgc tttggagaat ttgagcattc atatttggca tgatacgtag
    36661 gagtggcaaa tgagagcttg ttaattgagc tagtctgtct aaggaaatac cagcagccat
    36721 tgacatgata ggctgtttga actgtagagg gctaagaaca gtctcaaaga gctgtggctt
    36781 gatccctaga atgatgaagt caacctgatc gatcagctct tggtgagatt gggcgtagct
    36841 taggtgcaat tggccagcaa tttctttaga gcgagctaag gatgagcctg agatgattag
    36901 ctcgtgtggt gtgtgtgtta ggccttgaat gatagcagtt gccattttgc caacaccgat
    36961 aaatccaatt ttcataataa tgttcctaaa aatgaataaa ggctcaatag gctagagtgc
    37021 tcattgaacc ttagattcgc attttagcct tatccttcct agtatttctt gattaaatca
    37081 actgttgagc ggtcaagctt tttgacaatg gcttgcaaaa aggcctgtgc ttctacgaaa
    37141 tcatctaagg cgtacaagct ctgatgtgag tgaatgtagc gagcgcagac accgattgtg
    37201 gttgaaggga taccgccatt tttaaggtga gcagcaccgg cgtctgtacc gcctttacca
    37261 caataatatt ggaaggcaac cccagcctcc tcagcggtgg ttaataggaa gtctcgcatg
    37321 ttcttaagca tgatgtgtcc gggatcgtaa aagcgtagaa gggttccatc accaatatgg
    37381 ccaagattgc cataaatatc accagcaggt gagcaatcaa cagcaaagaa aagctcagga
    37441 tcaaatgtag tggctgacac atgggcacca cgaagcccga cttcttcttg gacatttgct
    37501 ccagcaataa gggtgttgtg aagtgtctgg tcttttaggg cttctagcag ctcagtgacc
    37561 atgagaacac catagcggtt gtcccaggcc tttgagatga tattcttttt attggcagtt
    37621 aaaatggttt cagactgcgg tacaataata tctcctggtg tgatgccaaa gctttcggct
    37681 tcagttttgt ctgtaaagcc accatcaaaa acaatatctg aaaccgctgg cagactagca
    37741 gcaccatttg ccccgcgcag aaaatgggga ggaactgagc ctgaaataac aggaatggct
    37801 tggccagcgc gagtgtataa ggtaaagcgc tgtgagctaa caactagtgg attccagccg
    37861 ccaatttcaa caacccgcag tgttccatca gctttaatct cgctcaccat aaagccaacc
    37921 tcgtccatgt gagccgcaac aagaatgcga ggagcttgat ccgccttgct ttcttttatc
    37981 ccaaatatgc cgccaagtcc atcaacctcc actcggtcaa caagcggcgt gatcttagcg
    38041 cgtaagtaat cccgaacagt gtgctcgtag ccggcgatgc cgtctaattc agtaacttct
    38101 ttaatttttg aaaataaatc aatcatttgt atactccatt tgtcatgtaa gattaaaggt
    38161 atcacgtctg cctctattct atcatttttt agtgaagaat gggaaacagc ttgagcatag
    38221 gaaaagagtt tgggagatta ggtgtgtctt tcttgcttga taagctgctt attatcagtt
    38281 tgattcagat gagataactg ctggtattga tggaatgaaa cagctatgca caacagcctt
    38341 gacaaggatc gacaggcctg agctgtctta tgctatcaat tgcacttagg tagagcagta
    38401 gcctgatatt gatgtgatta gttgctcttg tcaggtggtt tattagtatt tcctaaagtg
    38461 tcagctagtc ttggctgaga ttgttagctt ttgctctagc ctattattcc ctttttgtga
    38521 taaaatgaaa ggtatgaatg gaaaaaagac acgtattgtt tcaggattaa ttggactggg
    38581 tctgctagcc ggcttgggat tgaggcttaa ggaagtctat caagaaagag agcgtcagag
    38641 agtattggtt gaattgcgcg cctttttctc agccttagga gagattgagg tcttgtacat
    38701 caactccttt agctcaaagc gtgatgatgt cactggtggc cttgtcatga cagatggtaa
    38761 gacctatact taccattacc acaaaggaag tattgatttt aaagaggatt tgacatgatt
    38821 attccaacat ctaaggaaga acttgctagg ctaattgaga cagagcctag gctggttttg
    38881 ttttttacag cagattggtg tccggattgc cagtatatct atcctgtaat gcctgagcta
    38941 gaggctgaaa acccggatat gacctttgtc cgccttgatc gcgatgattt tatcgattta
    39001 gcgcaggatt ggcaaatttt tggcattcca agctttcttg ttatggaaaa ggggcaggag
    39061 aagggccgtt tggtcaatag attacgaaaa acaaaggctg agattagtga ctttctagca
    39121 gcctatcact aagaggagaa aatgagatga tttttgcata taataaagag caggtcggtg
    39181 atgttttgat ggtgatacta gaggataaaa aagacatcaa gcgacaggtt gagcgtaagg
    39241 ggagagtagc gcgtgttttt gcagaagaga cagggcaaac ccttgcttgg aatatttttg
    39301 aggcgtcagc cttaatcgct gttgagggaa atgggcaggt tttcttgtct gaggaggagt
    39361 tagcgatttt aaatgcggag cttgctcaag aagggtttac tgaacgatta gaggctagcc
    39421 cagcccctgt ttttgttgtg gggcaaatca ttgagatgat tcctcaccca gatagtgatc
    39481 atttgaatat ctgtcaggta cagattgctc ctgataaggc tgtgcaaatc gttgcaggag
    39541 cacctaatgc tgctgttggg ttaaaaacaa ttgttgcctt gccaggtgct atgatgccaa
    39601 gtggcagcct tatttttcca ggaaagcttc gtgggaagga aagctttggt atgatgtgtt
    39661 ctccacgcga attggccttg ccaaatgctc cacaaaagcg tggtattatt gagcttggtg
    39721 atgctgcagc ggttggtgaa gcctttgatc ctgctaagca ttggcagagc tagcaggact
    39781 tgatcagcat taaaatggtg tttagtcctt cttttgcttg gtgaaaagcc tttggacctt
    39841 gagccatgca gtgctttttg ctggtctgtg actgtcttta gcttcaggat cgaagcatta
    39901 gagtagctgc ttaacttatt gtcagcgctg ttgattgcag tagcgctatg cttgtgacaa
    39961 gtgaaggcaa agcctatcaa tgcccttggc tagggctaaa aattgtcttt agagtcactt
    40021 ttgaggtgag tagctcgcta atttcggtat tgaacggtgc ttaggtaccg tttttttaag
    40081 ctttgctgag tgtgacatgc tgaaaaaagg ccatgtcttt atatggcttt tggtcacaga
    40141 tggctaattc aatcgtccgc aacacttcca gccaatcagg cttagcttta acctcatttg
    40201 gttgaagtcc gtagcatgtc cgcagtccac gatagccttg gagcttcaaa tcggtctttc
    40261 tgagtaagtc atcaatactg taggtctgac ctgctgcaaa ggataaactt tcaaaggctt
    40321 gtccatttag cacattaagt gccttgtcat agtcgtgttc aaaaataaca gagtggagaa
    40381 cttttccgac ttgattgtgc ttgatgagtg atagctgccc tttaggcttc aatagacgtt
    40441 ccatctgagc taggtagatc gcatgctctt ttggggcgat atattctaag acattgtggc
    40501 atatgatcat atcaaaggct tgatcaggca gtttttctag cgcttctaat gaacctttta
    40561 ttttatgaat gctttcttgc ttttgggcaa ataataggtc aggatttggc tcaattgcag
    40621 ttacttcatt ctggacggct aatgcctctg ctgtgatgca aaagcctgct ccgaaatcta
    40681 aaatagtctt gcctgctatg gggcctaatt gggcaaagat caaatcatac atgagctttc
    40741 cccagggcct tgtgagcatg tcttgatagg ctttaagatt aatagtcatt atctagtttt
    40801 cctttcttta gctgctgtga gctattggca ggatttctaa acttcacagc ttgtccttat
    40861 tttaccatgt tttacgaata ataagataag gaggtatgac atgtacaata aagtaatctt
    40921 gataggccgt ttagtggcca agccagaatt aaacaagaca ttaacggata agcaggtcgt
    40981 tcgatttacc ttagcagtta atcgtcggtt taagacgacg actggtgagc gtgaggtgga
    41041 ttttatcaat gctgttgctt ggggaggttt ggctgaaacc ttggcttcct atgctagcaa
    41101 ggggagtctg ctgtcacttg atggcgagct tcgcacacga aaatatgaca aggcgggtca
    41161 gactcatttt gtgacagagg ttttgtgtca ttcttttcaa ttgctggaaa gtcgagcgca
    41221 acgagctata cgtgaaaaca acgctgctaa tgatttgatt gatttggctt tagaggagga
    41281 aaagcttccc ttttaaagac agctgctagc ttactgtcgc taagggagtc agacactagc
    41341 attgtgtatg ctagagatct caacataatc taaaaaatgg caacgattct aaaaaaaatc
    41401 ttgacacgtc ttagaaaaag gtttacaatg tatgacaatt aaaatgaaag aaaacaggag
    41461 gtgctggtat ggtagcagtt agcacagctc agacgatgac taagcgttat tactttagct
    41521 tctttagata gtgtttgtag acatgagcgc atggatacaa acacactgaa cgttatgttt
    41581 gtatctatgg ggctaagggc tatttgagtt gtttgtccac atagatgata tctcttctaa
    41641 gtggacacca tacagcatgt attttgttat ctcatgatac ctgtatagga ccatttagat
    41701 tatctagatg gtcttatttt tatgcaagaa agaggaaatg acatgagatt taaacagtta
    41761 tccttaacag cctttatagg gcttttggca atgctgctaa cggcttgtcg acaagaaacc
    41821 aaccaaacac atcaagctgc tagagttggg attattcaat atgctgagca ctcagcccta
    41881 gatgctgcgc gtgagggttt tattgaggcg cttgagcagg gcggctttag agaggggaag
    41941 aacctgacca ttacaaccaa aaatgcacag ggtgatcagg ctaacctgca aacaatggtg
    42001 gagcagctgg cgggtaagaa cgatttgcag cttgcgatcg caacgccggc agcgcaggcg
    42061 cttttaaata tggactcaga gacaccagct gtatttacag cggtaacaga tcctgtctca
    42121 gcaggtctgg ttgatacatt agctaagcct ggtgggaata tgacaggctc tacagatgcg
    42181 actgatgttg agaatcagat tgatttgttg accaaggcgc tgcctcaagc taggacagtt
    42241 gggattttct acaattcaag cgaggtgaat tcggagatac aggctaagaa ggccaagagg
    42301 gagcttgaga aaaaaggctt aaaggtcctt atgaaaaccg taaccactac taatgatgtg
    42361 cagcaggtta tgacaagctt ggctagtcag gttgacgctg tttacctgcc aacagataat
    42421 acggttgcct caacagctac tactattggg gatattttaa aggaggccaa aattccttca
    42481 atgggaagcg atgctgctta cctgagtgct gttttgttca cctcaggtgt tgattaccat
    42541 gctattggca tgcaggctgg tcagcaggcg gtagatattt taaagggtaa aaaaccagca
    42601 agcattcagg ttgctaagcc tcaaaaggca agcattgctg ttaatgatga tatggcaaga
    42661 cttctgggca ttgaccccga ggtgatcaag gctcttgcaa gtaacggagc caactagcgt
    42721 tttaggagga aggtatgaaa aaaggaagct atttaatact gttagtgctt gcaggcttcg
    42781 ttttggtggc ttgtcgttcg acagctagtc ctcgtaaggt taaccaatct catgttaaca
    42841 tcggtatttt acaatacatg gaacatgatt cgctgacggc agctcgtcga ggctttgaag
    42901 cgcaattaaa ggcagcgggc tatactaagg gagacaagct gagccttcat tatcaaaatg
    42961 cacagggcga ccaagctaat ttacagacga tttcagagca gctagtgaag caaaatgatt
    43021 tgatcttggc gattgcgaca ccggcagcgc aagccttagc gaccgtctca tcagatagac
    43081 caattgtttt tacagcagta acagatccta tctcagcagg cttagtggat aggatcaaaa
    43141 agcctggtgg cttgataaca ggaacaagtg accaggcgcc gattgcaaag caaattgact
    43201 tgttagccca agccttgcca gaggccaaaa ctattggcat tttatacaca gctagtgaac
    43261 gtaatgctga ggtgcaggta aaggaagctg aaacgctact gaccaaggtt ggttataggg
    43321 ttattaaaaa gggaattgcc acttcaaatg atgtgcaaga tactgctgca agcttgatga
    43381 gagcagtaga cgcgcttttt gtaccgacag ataataccgt tgcttcaacc atgacaatgc
    43441 tgggtgagct gtcattggct aataaggttc caattattgg tggctcaacg gatatggttg
    43501 atgcaggtgg gctcttgacc tatggtatcg actacgagag ccttggtaga caggctggag
    43561 aaatggccat taagatttta agaggacagg atccagcaag cctagcagtg gagtacccaa
    43621 aaacagtcaa gctacatatc aatcaagcaa tggcagacaa gctagcgatt gatacttcca
    43681 cattatcagt tgactaaatt gctaggttaa aggctaaatg actgatctct agccagctgg
    43741 ctaaatgaca aagtcttaac cagttagctt agcttactat taacgattca tatgacaaaa
    43801 aaggagaaat catgtcactc attttatcga gcttatcaca gggcttattg tggtctatta
    43861 tggcaattgg tgtttacctg acatttcgta ttttagatat tgccgattta actgcagaag
    43921 gttcctatcc gcttggggca gctatttgtg caacgggtat tgtatcaggt gtttctccct
    43981 tgctggctac gtttttagct tttattggag gcttgctggc aggccttgtc tcaggattag
    44041 ttcacaccaa attaaaaata ccagccttac taacaggaat tatcactctg acaggcttgt
    44101 attctgtgaa tctaaaggtg ctaggaagag ccaatgtggc tttattacgt caaagaactt
    44161 tagttaccca gctctatgat ctaggcttta ccaagcttgc agcggtgcta attatgggct
    44221 ttgtctttgt gaccattgtg atttttttat tagccctgct gatgaaaact cagcttggcc
    44281 tagctctgcg atcgaccgga gacaataatc caatgagtga agccaatggt atcaaaacag
    44341 atcagatgaa aatcatgggg tatatgctat ctaacggttt gattgcccta tgtggtgcct
    44401 tgctttgtca gaataatggc tatgcagatt taaatgctgg tgttgggaca attgttattg
    44461 ggctggcttc gattatcatt gctgaggtga tgattaggca gctaagcatt ggctggcgct
    44521 tagcttccat tgttttaggc tctattgttt atcgcttaat tattctagct atcctagcca
    44581 ttcccggtat ggatgcagat ttggttaagc ttttttcagc catgctattg gcagctgttc
    44641 tttttgtgcc agaattacag caaaggcttc gccttcgaaa aacaagttta ggataggaga
    44701 aatcatgtca gcaatattat caattaaggc tattcacaaa acatttgaag caggtacgat
    44761 taacgaaaat catgtcttga gaggcttatc tttggacatt gaggaggggg attttatctc
    44821 ggttatcggt gggaatggcg ctggaaaatc cacattaatg aatactctag caggcactct
    44881 ggcttttgat cagggcgata ttcttttaga gggaaaatca atcaagcatt tatcagccgc
    44941 taagcgtgcc aaggacatca gtcgagtgtt tcaagaccct aagatgggaa ccgcttcacg
    45001 cttgaccatt gaggaaaata tggctattgc ttaccgccga gggaaatcaa gggggctagg
    45061 ctggggcgtt aaagaaagag agcgccagat ctatcgtcag gccttgcagg aattaggcct
    45121 aaatctggaa aaccgtctta aggccgagac acagttttta tcaggagggc aaagacaagc
    45181 cttgaccctg ttaatggctt ccttagcaaa gcctaaggtc ttgttgctag atgagcatac
    45241 cgcagctctt gatcctaaga ccagtacaat ggtaatggct ttgacaaagc agcttgttga
    45301 gacacatggc ttgacaaccc tgatgattac ccataatttg gaaaatgcta ttgcttatgg
    45361 taatcgtctg gtcatgctcc atcaaggtaa tattgtggtg gatattaaga gagaagagaa
    45421 ggccaagctg acggttgacc acttgatggc actctttcac caaaatagtg gtcatacgct
    45481 ccttgatgat gcacttgttt tgggataggc taggtgaggg ttagctctgt tttcaaatag
    45541 cagccataat gaaaaggctt aaagccaacg cttctagaaa cgctagctca agccttgtta
    45601 taatacttag gagatttttc taagagtgat aaagccatga tgacgtctat tgtagtcaaa
    45661 ggatttgttt cggatgcgat aagcctcatt ttccacaatt tcaattgcct tattcagctg
    45721 ctgaatggta atcgcctcat caatctcatg aaaagcagtg ctataataat cctcactaac
    45781 acgttgattg cggtctttat aggtattttt atgctctgtt aaaatggcct tagcctcagc
    45841 acgttttgca atggtatcta taataccttg accatatgct ctagcctctt gaaggattga
    45901 cagcatattg tctagagaat atgcgtttgc taagcggctg acaaagctat cagcgacctc
    45961 aggacttaaa ttaataccat ctaagtgata aatcatctct gggtgtagct ttaggtaata
    46021 ctgcaattcg cggaacaaaa gcgctggaat tttcgacgaa tccctatatg gattgagctg
    46081 aatctcctga ctatgtagcc tattgataaa atcgtccttg aactgcttaa tagcatcgta
    46141 gtctgatttt tctagctctg ctttaatatt ggctagaatc tgggcgtctg aataacgacg
    46201 atagcttgat agtgaagcag caggcctact agtattggaa tttcgagaag cttctgctct
    46261 tctagtctct ttgcttggtg tttgctgctt atttgactga gtctcctgct cggttagtcg
    46321 tagctcaggg tgtaaacgac taatattgtt aagaaattgg ttaacctcat attctgatga
    46381 aaactttagc ctaggtctgg ccttgacctt ctcaatagcc ttgtcaataa tccttttccc
    46441 gtaccttttg agattactgt cagactggat caaataaaga ttaacatgta agtgatcttg
    46501 actatccgcc ttagataagc tgttaccaag gccaaggctt cctaagagcg tagctagtaa
    46561 cagcaggtgt tttactagac tacgctgaac aatattgtga cgactaagca taagttattt
    46621 tcccattcta ttgtaatata ccagaaaatg ttatcaaaat aaagataaga tgtcaatgtc
    46681 attaatggtg gttaatcttt aattaatggt cgttaatcta gtatatcaga gagctagctt
    46741 aggctggcag tggtcattct gtgcgtcttg gtacgaaatg cccaagcaga tgcagctcac
    46801 tagaatgatc aatagcctca acacaaagcc ccttacagct tgacacaagc tgtaaggggc
    46861 tttgttgtat taacagataa ctcaaatcct tgctttttat aataaatcta aggtttttag
    46921 cttgtcatca atcatgtgca gaacggttgc caaatcctct gggttttgca cgaaatcaag
    46981 cttgtttcca tcaatcttca tcttaggtga aacgtcatat tgctcatacc agcttgggta
    47041 ttcaccatgt acctgatggt aataggcttc taagtcagga ttgtcgtcaa cctgctcaaa
    47101 acgtctgccg cgcttttcaa tgcgctctag catcttctca aaggagacat caatataaat
    47161 cagcagatca ggccgttttt aaggcattcc ttcaagctcc tctagcatat tggctaagag
    47221 ctcttggtaa atttcaagct ctgtcttggt aacatttcca tttttatagt taagtgtcaa
    47281 gaagagctca tcttcaaaga ttgagcggtc aagaatatta ttgtctgcct ggtaggcttc
    47341 tttaatagat ttgaagcgct tgttcaaaaa gaaaatttgt agtaaaaagg catatttttt
    47401 agggtcttgg taatacagat caagaacagg attgttatca acagcctcgt aaaatacctc
    47461 tgttcctaaa tgctcaccca gtgcagcagc aagggaactc ttgcctgcgc cgattgttcc
    47521 agctaataca atcaacatgt ttctccttct atgtagtctt agtgtatttg tgcaaaaatc
    47581 gtttcaacct cagctaaggt tttagcgcgt gaaacggcac tgcgaatttt ggcagcgcct
    47641 gctgtccctc gcaggtaatg aggggctaac ccacgaaatt cacgaacagc aatagcttct
    47701 cccttgagcc tgatgaggcg cttgagatgg tctttagcaa tatctagctt tttagcaaag
    47761 ggcagctctg gcaaaacctc tcctgtctca aagaagtgat taatttgggt gaagagataa
    47821 gggttgttca tagctgcacg gccaatcatg accgcatcta caccaatctc ctcaatcatg
    47881 aacctagcgt cctgaacagt tctgacatct ccatttccaa taaatggaat cctggtaata
    47941 gctcttgaga cgcgtgcaag ggtttcatgg tcacaggtgc cagtatacat ctgctcacga
    48001 gtacggccat gcatggcaag agctgacaca ccagcagctt cagcagccaa ggcattctca
    48061 acagctagtg agctgtctgc ccagccggta cgcattttga cagtcagtgg aatgtctaaa
    48121 acagaggtta cctcctgaat gatatggtaa atcttatcag gatcgcgaag ccacttggca
    48181 cctgcttcat ttttaaccac cttgttaaca ggacagccca tattgatgtc aacaatgtca
    48241 gccttggtat ggctctggat aaaatcagcc gcacgcttta gtccttcagc gtcaccgcca
    48301 aatagttgga ttgacatggg gtgctcattg tcatcaatat gaagcatatg cagggttttt
    48361 tcgttattat agagaagtcc cttttcagaa atcatttcca tgacaacaag gcctgcacca
    48421 aattccttgg caatcgtgcg aaaggccgaa ttggtcacac cagccatagg tgcaagcact
    48481 gtacggtgag ggatttccac atgaccaatc ctaaagggtg agttaagcct tgtcattgat
    48541 cagcacctcc aaatcagttt ggtcaaattg gtacttggtg ccacaaaatt ggcaaacaat
    48601 ttcagccccc ttatcctcgt ttagcattgt caacaggtca gctttaggga ggctcattag
    48661 ggctgacgca aagcgctctc ttgagcagtc acactgaaag ctcagctgct cttcagctaa
    48721 tcgcttgtaa ggctcttcac cataaatagc tgctaacaga gcgtctatat gattttccga
    48781 cgctagaagg gttgaaatcg caggcatttc ctgaatgcgc ttctcatagt ggctaatctc
    48841 ttcgacagaa gctccaggca gcacctgcag cataaagccg ccagcaacct tgaccttgtc
    48901 ctcttgatct agaagcacat taaggccgac agcagatggt gtctgctcag actctgtcaa
    48961 gtagtaggcc agatcctcac caatctcacc ggtaatcaag ggtgttgtag aggtgtaggg
    49021 attgcctgtt ccatagtccg taattgtcac aaagtgtccc tgtcccataa aaggaccaac
    49081 cagtacttct ccagttgctg tttttttgat atcaacaccg ggattttgaa tatagccctt
    49141 gacatgccct tttgtgtcag caacagaaat aatatgccca aaggaggaat cgccaataac
    49201 cttgacagta accttactat ctcctttttg gttggcagct agaatctgat tggcaatcaa
    49261 ggtacgacca agtgcaaccg ttgaagatga taaggtatga tgcctttcct gagcatatcg
    49321 aacagtttcg gtgcaatcca aaacataggc cctgaaggca ccggaggcag aaattgtttt
    49381 aattagttta tccataattt ctattatagc ataatgaaca aggcttgtgc tggttgcttt
    49441 agaggaaagc tgcttgaaaa tagagaaaca ctatttggtt aataatagca gctctataaa
    49501 gccacttaaa aacagagcag tgctaacaaa tggtagtatt cttgtcctta gcacgcagta
    49561 agctaatcac ctaagtcagt acaatcaaac aagcatcaaa aaacagctcc gataggttga
    49621 ttaaaggaag aaatgataaa agagttattt cgtaatgctt tgctgataat gagcaaggta
    49681 atcatgtggt gtcgtatcag tgtacttttt gaaggttttc aaaaaatggg tggtatcgta
    49741 gaaataaagg agcttagcca cttctccagc tggtactcct cttcgtaaaa gtagcttggc
    49801 ttcttgtact ttttccttca aaatataggt ctgcaacgaa atagaagaat acattttaaa
    49861 aacagctcgt aaatgtgact ctgagatata aagatgctta gcaatatctg atacctttaa
    49921 ttttgaataa aggtgcttat cgacgtaata taaaatacta ttataaattt gctgcttatc
    49981 agaaacactt ttgttagtca atgattctga gaggctaata atagcagctg ctcttatttg
    50041 aagcacctta aggagatctg tagctttttc agttaggttc ataaaatgct taatgcgctc
    50101 gtagtttttg gcaacatcag tattttcagt aaagcttagt tcaagcagct taataaaata
    50161 aataatagaa agattttttt cagctcttaa tgcgggaata gaagaggaga cgacatctga
    50221 tgaagggata caattgattt cgtgctttaa tagctctgta ttacccagct tgactaaatc
    50281 aataatatga ttcaaataat ttaagacagc tggcacatga aatgacgggg tattttccaa
    50341 ttcgagatta gctataatat gaggatcctc ccagattagc tgggcttcct ccagtaaatc
    50401 attaatgctt tgctggcagc tcatttcaaa gttggtgtca aaaaaggcat caacagctat
    50461 caaaaggctt cgaatatgag aagcaggaaa atgaggaatg gtagagatat agccaactag
    50521 ctcttttttt gacttatcag gatagcgctt caagaagcta tcggctaatt cctccttata
    50581 gctatcctga aagaaagagg tgtaaaaagg cccaatgaaa ataaacttgt caccaatagg
    50641 aaacattaga gaggattcct caagcgttcc ctcataacaa gtgagctcag tattactagg
    50701 aatatctaat gttttaatta attcatagta ggggaatcga cgctcctcgt catcataagc
    50761 ctgaaggagc tcaagatttt gagaaagcac taaaacaggt aattgtgata ggttatgcaa
//
LOCUS       DARYNN010000009        50812 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.009, whole genome shotgun sequence.
ACCESSION   DARYNN010000009 DARYNN010000000
VERSION     DARYNN010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 50812)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50812)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50812
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.009"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            110..637
                     /locus_tag="TVB59_000461"
     CDS             110..637
                     /locus_tag="TVB59_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEL1009399.1"
                     /translation="MSVDDYRPTYAVEAVYDLRANDLLRQGITAVLVDLDNTLIAWDN
                     PDGTPEVRAWLDEMTIADISVVVVSNNTYSRVERAVSRFGVDFIARAMKPFAYGINKA
                     IDRYGFDRDEVIMVGDQLMTDIRASHRAGIKSVLVKPLVTSDAWNTKVNRWRERRVLA
                     KLEEKYGRLVYQKGI"
     gene            637..1755
                     /gene="yqeH"
                     /locus_tag="TVB59_000462"
     CDS             637..1755
                     /gene="yqeH"
                     /locus_tag="TVB59_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEL1009400.1"
                     /translation="MEELFCIGCGIQIQTTRKQEAGFTPAAALVKGIEAREIYCQRCF
                     RLRHYNDITDVHITDEEFLRLLHEVGDSDALVVNVIDIFDFNGSVIPGLSRFVAGNDV
                     LLVGNKKDILPKSVKDSKVTQWLTERAHEEGLRPLDVLLTSAQNKYAIKELIERIDQL
                     RQGRDVYVVGVTNVGKSTLINAIIQEITGDKDVITTSRFPGTTLDKIEIPLDDGSFIF
                     DTPGIIHRHQMAHYLSAKNLKFISPKKEIKPKTYQLNPEQTLFLGGLARFDFISGERQ
                     GFTAYFDNQLLLHRTKLEGADAFYDKQAGQLLTPPDKKELDDFPRLVRHEFLLDQKVD
                     VVFSGLGWIRVNANKETATKVAAWAPDGVAVVVRKAII"
     gene            1782..2123
                     /gene="yhbY"
                     /locus_tag="TVB59_000463"
     CDS             1782..2123
                     /gene="yhbY"
                     /locus_tag="TVB59_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEL1009401.1"
                     /translation="MLTSKQRAFLKAEAHSLKPIVQIGKNGLNDQIKTSIRQALDARE
                     LIKVTLLQNTDETIHEVAEILEEEIGCDTVLKIGRILILFKVSAKKDNILFKVSAKKD
                     NRKLSVKVKSI"
     gene            2207..2839
                     /locus_tag="TVB59_000464"
     CDS             2207..2839
                     /locus_tag="TVB59_000464"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEL1009402.1"
                     /translation="MALELLTPFTRVELEMEKKDSNRKQVGILGGNFNPVHNAHLVVA
                     DQVRQQLGLDQVLLMPEFKPPHVDHKETIDEKHRLRMLELAIQETEGLAIEEIELTRQ
                     GVSYTYDTMKLLIEQNPDVDYYFIIGADMVDYLPKWHRIDELIHMVQFVGVQRPKYKA
                     GTSYPVIWVDVPLLDISSSMIRDFIQSDRQPNHLLPKAVLDYIHKEGLYQ"
     gene            2836..3429
                     /gene="yqeK"
                     /locus_tag="TVB59_000465"
     CDS             2836..3429
                     /gene="yqeK"
                     /locus_tag="TVB59_000465"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEL1009403.1"
                     /translation="MMYQDYVGYRRDELLGKIAEQMSDKRFKHVLGVERAAIHLAERY
                     HCDPIKAGLAALLHDYAKECPDELFISLIDKYQLDPELLKWNNNIWHGMVGIYKLQED
                     LGLKDKGILRAIEIHTVGAAEMTILDKILYVADYIEEGRVFPLVDEARRIAELDLDKA
                     VAYETAHTVAYLASKAQPIFPQTIDTYNAFVHYLHEE"
     gene            3431..3784
                     /gene="rsfS"
                     /locus_tag="TVB59_000466"
     CDS             3431..3784
                     /gene="rsfS"
                     /locus_tag="TVB59_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEL1009404.1"
                     /translation="MRKEELLEIVIKAADEKRAEDMLALDLAGLTSLTDYFVIVTATN
                     SRQLEAIADNIRERVKEASGDASHVEGNSQTGWVLLDLNDVVVHIFSEDERYHYNLEK
                     LWHEAPAVELSHYLG"
     gene            3914..4657
                     /locus_tag="TVB59_000467"
     CDS             3914..4657
                     /locus_tag="TVB59_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL1009405.1"
                     /translation="MQKNYDTFASVYDAIMDDSLYDKWTAFSLRHLPKNKEHQKLLEL
                     ACGTGIQSVRFAQSGFEVTGLDLSQEMLEVAKKRAQSAKKIITFVQGNMLDLSQVGSF
                     DVVTCYSDSICYMQDEIEVGDVFKEVYQVLNDGGIFMFDVHSIYQMDHLFPGYSYHEN
                     AEEFAMVWDTYKAEAPHSVVHELTFFIQAEDGHFLRFDEVHEERTYDILTYDILLEQA
                     GFKSFKVYADFEDQEPTKTSKRWFFVAQK"
     gene            4767..5867
                     /locus_tag="TVB59_000468"
     CDS             4767..5867
                     /locus_tag="TVB59_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEL1009406.1"
                     /translation="MTVTGIIAEFNPFHYGHQYLLSQAKGLKIVAMSGNFVQRGEPAL
                     VDKWVRAQMALENGADLVVELPFLVSVQSADYFAQGAVDILMRLGIDTLAFGTEQLLD
                     YQKLSRLYSEQAEHMTAYLATLPDHLSYPQKTQSMWEAFAGLSATGDRPNHLLALSYV
                     KASAGKKLQLQPIKRLGAGFHSEAKDQCLSSATAIRKHIADRAFVEKSSPNAALILRA
                     PQVTWEHYFPFLKYHILTAPDLTQFFQVNDELASRISAAIRSVATVDELVEAVATKHY
                     TKARVRRVLTYILVKAVEAPLPEGIHVLGFSKKGQAHLKTIKASVPLISRIGAKPWDQ
                     LTQRADTVYQLGHTDMPEQTWGCVPIRPEAMN"
     gene            6223..6930
                     /locus_tag="TVB59_000469"
     CDS             6223..6930
                     /locus_tag="TVB59_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEL1009407.1"
                     /translation="MKTVKEVSQLTGLSVRTLHEIGLLPPTMVGENGYRFYDAAALRR
                     LQDILLFRELAFPLKTIKQLLDSPSYDQQAALAAQIKMLELRKAHLEKVIAHARTLQK
                     GEETMTFDIYSKSQLEAFQLEAKERWGETEAYMAYEAKVNQPSAEQLIKDMGEIFSIF
                     GRMLDQPVAELAVQQQVKALQDYISQHFYDCSTEILSALGCMYLEDDRFRAAIDHMGG
                     AGTAAFVSRAISYYCQH"
     gene            7071..7787
                     /locus_tag="TVB59_000470"
     CDS             7071..7787
                     /locus_tag="TVB59_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1009408.1"
                     /translation="MGRKWANIVAKKTAKDGATSKVYAKFGVEIYVAAKQGEPDPELN
                     TALKFVIDRAKQAQVPKHVIDKAIDKAKGNTDETFVEGRYEGFGPNGSMIIVDTLTSN
                     VNRTAANVRAAYGKNGGNMGAAGSVSYLFDKKGVIVFKGDDADSIFELLLEADVDVDD
                     VEAEDGSITVYTAPTDLHKAILALRESGISEFQVTELEMIPQSEVTLEGDDLAVFEKL
                     VDALEADDDVQKVYHNVADV"
     gene            8009..8854
                     /locus_tag="TVB59_000471"
     CDS             8009..8854
                     /locus_tag="TVB59_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL1009409.1"
                     /translation="MTIKRYLGLAGLAVLSVGMLAACGTKEKSASSTKDTPKEVIFAT
                     VGTTAPFSFEKEGQLTGYDIEVAKAVFKDAEKYKLQFKKTEWSSIFTGLDSGKYQMGG
                     NNISYTKERSVKYLFSYPIGATPSVLVVPKDSDIKSYDDIKGHSTQVVQGTTTAAQLK
                     AFNEEHADNPVELKFTNETITQMLTNLNEGKADFKIFDAPTVNAIIDNQGLDHLKTIE
                     LATSEQPFIYFIFSQDQEELQAFVNKRLEELTADGTLSKIAKKYLGGDYVPAKQDLKL
                     PTAKS"
     gene            9226..10071
                     /locus_tag="TVB59_000472"
     CDS             9226..10071
                     /locus_tag="TVB59_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEL1009410.1"
                     /translation="MNIKKAVGFVSLALASIALVACSGKQDDKNTLTIGVMTKTASDQ
                     ARWDKIEELLKKDKITLKYKEFTDYSQPNKAVANGEVDINSFQHYNFLDNWNKENKAD
                     LKAIAETYISPIHLFSGTSQDGKAKYQSVDELPDGAQIAVPNDATNESRALYVLQAAG
                     LIKLNVSGDKLATIANITENKKKLDIKELDASQTARALTSADAAIVNNSYAVPAKIDF
                     KTSLFKEKADENAKQWINIIAAQKDWEKSAKADAIKALIKAYHTDAVKKVVDKTSNGV
                     DVPVW"
     gene            10149..11519
                     /locus_tag="TVB59_000473"
     CDS             10149..11519
                     /locus_tag="TVB59_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEL1009411.1"
                     /translation="MTKTDQQYLTRLWEDQLTQDYLVSLGQLIASRSIFAQGIGLEET
                     AAYLKELFAQAGAEAIVDKTYAAPFVLARFNSSRPAAKTLIFYNHYDTVPADSDQKWT
                     SDPFTLTERDGYLFARGVDDDKGHIIARLTAVVRYLKEHADLPLNIVFMMEGAEESAS
                     VDLDRYLAKYADQLKGAELLIWEQGIRNEHDQLEITGGNKGILTFEMSVDSARCDIHF
                     KYGGVIESAAWYLLQALSSLRNHRGELLVPGIYQKVVPPTERELDLVETYAIENAQAL
                     KKLYGLELPMLQSERRQLLAAYYFQPSINIQGLWTGYQGQGVKTIIPSQATPKMEVRL
                     VPGLEPEYVFDQIRSYLLNKGFDQIKLTYTLGEMSYRSDLSSSAISQLIAAAQPFYPK
                     GLSLLPTSAGTGPMHTVFEALQVPIAAFGLGHSNSCDHAGDENIAIVDYCRHIALIEE
                     LITSYE"
     gene            11512..12576
                     /locus_tag="TVB59_000474"
     CDS             11512..12576
                     /locus_tag="TVB59_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEL1009412.1"
                     /translation="MSEPMIQLDHIDITFHQKKRVIEAVKDVTLHINQGDIYGIVGYS
                     GAGKSTLVRVINLLQQPTKGSITIDGELTFDQGKVQLSANSLREKRRDIGMIFQHFNL
                     MAQKTAKENVAFALRHSRLPKAERERKVTELLELVGLSERADNYPAQLSGGQKQRVAI
                     ARALANDPKILISDEATSALDPKTTKQILALLQELNRRLGLTIVMITHEMQIVKDICH
                     RVAVMQQGTLIEEGSVLDIFSNPREPLTQEFIKTATGIDEALEKINQQDIVKELPANA
                     ILAQLKYAGTSTDEPLLNQIYRQFEVTANILYGNIEILDQVPVGEMIVVFEGAAASIE
                     AAEKALHEAGVDVTILKRGA"
     gene            12577..13269
                     /locus_tag="TVB59_000475"
     CDS             12577..13269
                     /locus_tag="TVB59_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1009413.1"
                     /translation="MLELFQAYLPNVYELGWSGDAGWGVAIWNTLYMTIVPFIVGGAI
                     GLFIGLLLVLMGPDGVIENRLVCWLLDKLTSIFRAIPFVILIAILASFTYLIMGTTLG
                     ATAALVPLTFATFPFFARQVQVVFSELDRGVIEAAQASGATFWDIVRVYLSEGLPDLI
                     RVSTVTLISLVGETAMAGAIGAGGLGNVAISYGYNRFNNDVTWVATLIILLLIFAIQF
                     IGDSLTRHFSHK"
     gene            complement(13314..14699)
                     /gene="brnQ"
                     /locus_tag="TVB59_000476"
     CDS             complement(13314..14699)
                     /gene="brnQ"
                     /locus_tag="TVB59_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEL1009414.1"
                     /translation="MKEKNVYIVIGFMLFALFFGAANLIYPAFLGIYSGQNIPWSIIG
                     FCLTGVSLPLLGVIAVARSGSDDVESLARPISKWYAILYSSILYLSIGPFFAIPRTGA
                     TSFSVGIAPILGDSIINKAIYAVLFFGLSYFLAIRPSKLAESIGKFLTPTLLVVITIL
                     IIASFVHPAGDYGEAFNAGAGINNAFKDVPFIAGLIQGYGTMDALASLVFAILVIEAT
                     KQFGAKTDQEITKITLISGAIAILLLAFVYIFVGRIGATSQSLFPFVDGHFTLNNSAV
                     NGGQILSHASRFYLGSIGQAFLAIVIFLACLTTSTGLITSSAEYFHKLMPRVSHVAWA
                     TLFTLVSAFFYFGGLSVIINWSSPILYLLYPLTVDLIVLVLIQKSFGNAPLVYRTTIG
                     LTIIPALYDALATLSQLTKLFTLPDGLSYFFERLVPLGQFSMGWISFSILGFVLGLII
                     SKTKGLHPTAS"
     gene            15127..16341
                     /gene="sstT"
                     /locus_tag="TVB59_000477"
     CDS             15127..16341
                     /gene="sstT"
                     /locus_tag="TVB59_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HEL1009415.1"
                     /translation="MKRIRDLWVRTNLIKKIGIGVVIGLLLGILLPDVTAIGILGQLF
                     VGALKAIAPLLVFALVAQAISHQRSGQQTNMTLIIVLYLLGTFLAALVAVIANYLFPL
                     TLTLNTPVNTELSPPQGIVQVFQTLLLKLVDNPINALATANYIGVLAWALIFGLALKS
                     VPSDFKHLIKTAADVTSQIVVWIINVAPIGIMGLVFSTVSENGISILSDYALLILVLV
                     GTMLFVALVVNPLLAFVLTHQNPYPLVFRCLKDSGLTAFFTRSSAANIPVNLQLCEDL
                     GLSQATYLVSIPLGAMINMGGAAITINVLTLAAVNTFGIQIDFLTALLLSVVAAISAC
                     GASGVTGGSLLLIPVACSLFGISSDLAMQVVGVGFIVGVIQDSCETALNSSTDVLFTA
                     IAENAFWKQKKA"
     gene            complement(16695..17369)
                     /locus_tag="TVB59_000478"
     CDS             complement(16695..17369)
                     /locus_tag="TVB59_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEL1009416.1"
                     /translation="MLKRKTVGVLGLGIFGRTVARELSNYDQDVIAIDIRESHVKEIA
                     DLATKAAVGDITDKDFLIAVGVEQCDTVVIASGNNLESSVLAVMHCKKLGVPTIIAKA
                     KNKIFEEVLYGIGATKVITPERDSGKRVASNLLRHHIESIIYLEHGISMIEFTIPKSW
                     EGKSLSELDVRRKYELNIIGMRQKEVKTLDTNVQPFEPLEADTIIVAIANDHTFEKFD
                     YLGYLK"
     gene            complement(17379..18755)
                     /locus_tag="TVB59_000479"
     CDS             complement(17379..18755)
                     /locus_tag="TVB59_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEL1009417.1"
                     /translation="MKRSFFKSLSVTQRLTFSFAIVILIGSLLLSMPFTHYSNGPNTV
                     YLDHFFNVVSMVCVTGLSVVPVADVYNGIGQTIAMMLMQIGGLGLVTLIAVSTFALKR
                     KMRLSDQTLLQSALNRGDSKDLKKYLFFAYKVTFSLEAFAALVIMTDFIPRFGWKNGI
                     FNSIFLAVSAFCNAGFDNLGSSSLKDFVLNPTINAIITFLIISGGLGFAVWVDLGTAF
                     KKYFFERPHCYGITFKKFSNQSRLVLQTTLVILVLGTFLSWFLEKDNLNTIARYNLPQ
                     QLMVSFFQTVTMRTAGFATISYNDTLAPTNILYMIQMVIGGAPGGTAGGIKITTAAIT
                     FLLFKAELSGQSEVTFRNRIIANKTIKQTMTVLIFFFAVLMIGYILLLSVEPDIAPIP
                     LLFESISAIATVGVSMDVTPHLSSAGRLIIIVLMFVGRVGPITVLISLIQRKEKTIQY
                     ATTDILVG"
     gene            complement(19268..19990)
                     /gene="rsmG"
                     /locus_tag="TVB59_000480"
     CDS             complement(19268..19990)
                     /gene="rsmG"
                     /locus_tag="TVB59_000480"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEL1009418.1"
                     /translation="MTPQAFYLVLEQAGFALTNHQKEQFDTYFKLLVDWNRKINLTAI
                     TEENEVYLKHFYDSVAPLLQGYIPNEPLRLLDIGAGAGFPSIPMKIMFPKLDVTIIDS
                     LNKRIHFLQLLAKELGLEGVHFYHGRAEDFGQDKQFRGQFDLVTARAVARMQILSELT
                     IPFLKIKGKLIALKAQAADQELEEAKKALQLLFAKVLDHQPYQLPNGDGRYITLVEKK
                     KETPNKYPRKAGIPNKNHCKRL"
     gene            20126..20683
                     /locus_tag="TVB59_000481"
     CDS             20126..20683
                     /locus_tag="TVB59_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEL1009419.1"
                     /translation="MPMFLVIVALIGVLVVWLMVSYNGLVKARMHTKEAWSQIDVQLK
                     RRNDLIPNLVETVKGYANHEEKTLEKITSLRSRVADATTPQATMAASNELSKQVTSLF
                     AVAESYPDLKANSNFLKLQEELTNTENKISYSRQLFNTTTSHYNLKLESFPSNLVAKL
                     FGFKPSEFLQVPEAEKEVPKVDFTV"
     gene            20720..21613
                     /gene="htpX"
                     /locus_tag="TVB59_000482"
     CDS             20720..21613
                     /gene="htpX"
                     /locus_tag="TVB59_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEL1009420.1"
                     /translation="MLYQQISQNKRRTVILLFAFFVLLVVIGAAAGYLLADSYQLGAA
                     FALIIGAIYAFSMIFQSTSLVMGMNKAKEITVNDAPDFFHIVEDMALVAQIPMPRVFI
                     IDDPSLNAFATGSSPQNAAVAATTGLLKVMNREELEAVIGHEVSHIRNYDIRISTIAV
                     ALASAVTLISSIGGRMMWYSGGRRRDNDRNDNGFGAIMLIFSILSLILAPLAASLVQL
                     AISRQREYLADASSVALTRNPEGMIRALQKLSNSQPMTHPVDDASAALYINEPRKKEK
                     LSALFSTHPPIEDRIERLKHM"
     gene            21901..22434
                     /locus_tag="TVB59_000483"
     CDS             21901..22434
                     /locus_tag="TVB59_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEL1009421.1"
                     /translation="MLSVSDIRKRPEGIRFEREYDVKEALLIRDPQVIDINNVRASGR
                     AQFDDGLYLLEYQLGYQITLPSSRSMAPVVLDEMQTVQELFIEEADVASKQEMVDENL
                     VLVLSEDQLDLEESIIDNILLAIPLQVLTEAEKESQILPTGEDWAVLTEEQYQAQQKE
                     KAKDNSPFAGLQGLFDE"
     gene            22619..23305
                     /gene="covR"
                     /locus_tag="TVB59_000484"
                     /gene_synonym="csrR"
     CDS             22619..23305
                     /gene="covR"
                     /locus_tag="TVB59_000484"
                     /gene_synonym="csrR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CovR"
                     /protein_id="HEL1009422.1"
                     /translation="MTKKILIIEDEKNLARFVSLELQHEGYEVTVEVNGREGLETALE
                     KDFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMTARDSIMDVVAGLDRGADDYIVK
                     PFAIEELLARIRAIFRRQDIESEKKTPSQGVYRDLVLNPQNRSVNRGDDEISLTKREY
                     DLLNILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTV
                     RGMGYVIREK"
     gene            23309..24799
                     /locus_tag="TVB59_000485"
     CDS             23309..24799
                     /locus_tag="TVB59_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing protein"
                     /protein_id="HEL1009423.1"
                     /translation="MAKQKKYKKTLPKRLSNLLFVLFFCIFSAFTLLAYISTNYFLLK
                     REKQTIFQAVNIVRVRLSEVDSNFTLENLAEVLYKNDRTHLKIDDANGSRIIRSERNI
                     TNTLNANEDIYVYNVDKQMIFTTDDEEASPGLNGTIGKVTKDHIEEQYKGFSMTQKVY
                     SNKTGKFVGYVQVFHDLENYYMIRARLFFWLLVVELFGVGLAYFIILIVTRNFLKPLN
                     NLHDVMRTISKNPDNLMLRSGISSGDEIEELSVIFDKMLDKIETHTRLQSRFISDVSH
                     ELRTPVAIIKGHIGLLQRWGKDDSAILDESLTAAAQEVDRMAIMINDMLDMIRVQGSF
                     EGHQNDTTVLESSIETVVGNFRVLREDFDFTWYSENQRTLAKIYKNHFEQALMILIDN
                     AVKYSRKEKKIVIELAVNASNEAVVKVKDRGEGISEEDIKHIFERFYRTDRSRNRTST
                     QAGLGIGLSILKQIVDGYHLHMEVESELNKGSVFILRIPLADHQGS"
     gene            24990..25484
                     /gene="nrdR"
                     /locus_tag="TVB59_000486"
     CDS             24990..25484
                     /gene="nrdR"
                     /locus_tag="TVB59_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEL1009424.1"
                     /translation="MRCPKCNYNKSSVVDSRQAEDGNTIRRRRECESCHTRFTTFERL
                     EELPLLVIKKDGTREQFSRDKILNGVVQSAQKRPVSSTDIENLISRIEQKVRTAYENE
                     VSSTVIGNLVMEELAELDEITYVRFASVYKSFKDLDEIEELLQQITNRVRGKKKSSVD
                     DEAY"
     gene            25468..26631
                     /locus_tag="TVB59_000487"
     CDS             25468..26631
                     /locus_tag="TVB59_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase loader"
                     /protein_id="HEL1009425.1"
                     /translation="MMKPIDTFSYIKHNQVQYDSSSLIQLYFPIIGNDAVAVYQYLVH
                     FFDDGSGAHKFSDILNHLQFGMKRLEEALVMLTAIDLLVLYQLPDAYLIKLHQPLGRE
                     AFLNNPIYRRLLEQKIGDVAVLELQMVIPNQARNISKTFSDVFGIDSQELKQPQPSKI
                     NFDLDSFQQLMRRDGLRFEDHQKDVISLYSISEQYHLTWFDTYQLAKATAVGGSIRPE
                     RMLVKKQQEGAQKTSESFSPAEQVVLRESKQDTPLVFLEKIKKARRARVTKDEKELLL
                     TLARMNFLDEVINIMVLYTFNKTKSANLHKTYLMKMANDFAYQRVLTAETAIIKTRAF
                     GERKQQAKSQQSNVPKWSNPDYQEKTSQEEQAKLEQFKQAALKRLENLGKSGD"
     gene            26632..27540
                     /gene="dnaI"
                     /locus_tag="TVB59_000488"
     CDS             26632..27540
                     /gene="dnaI"
                     /locus_tag="TVB59_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEL1009426.1"
                     /translation="MEKIGKMVEHLGQASRVASAELIEAILADQEVAEFIKAHQLSQA
                     EIKLSLSKFNQFLVERRKYQTGDETYIAKGYQPILVMNEGYADVSYLETRELVEAQRQ
                     AAIADRIHLVSLPRSYRRVSLSAVDVNNASRMQVFSELLDFVEQYPAAEQKGLYLYGD
                     MGVGKSYLMAAMAHELSEKKGVSTTLLHFPSFTIDVKNAISNGSVKEEIDAIKHVPVL
                     ILDDIGAEQATSWVRDEVLQVILQHRMLEDLPTFFTSNYSFADLERKWAKIKGNDETW
                     QAKRVMERVRYLARECHLEGVNRRQG"
     gene            27590..28900
                     /gene="der"
                     /locus_tag="TVB59_000489"
     CDS             27590..28900
                     /gene="der"
                     /locus_tag="TVB59_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEL1009427.1"
                     /translation="MVLPTVAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYT
                     TGEWLNRQFSLIDTGGIDDVDAPFMEQIKHQAHIAMDEADVIVFVVSGKEGVTDADEY
                     VSKLLYRTNKPVILVVNKVDNPEMRNDIYDFYSLGLGDSFPVSSVHGIGTGDVLDAII
                     DNLPIEEPVENDDVIRFSLIGRPNVGKSSLINAILGEERVIASPVAGTTRDAIDTSFT
                     DESGQAYTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDIVLMVINAEEGIRDYDK
                     RIAGFAHEAGKGMIIVVNKWDTIEKDNHTVARWEADIRDQFQFLTYAPIIFVSAVTKQ
                     RLNRLPELIKRISDSQSQRISSAILNDVIMDAIAINPTPTDKGRRLKIFYATQVSVKP
                     PTFVVFVNEEELMHFSYLRFLENQIRAAFTFEGTPIKLIARNRK"
     gene            29241..32333
                     /locus_tag="TVB59_000490"
     CDS             29241..32333
                     /locus_tag="TVB59_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL1009428.1"
                     /translation="MARLIPGRIRNQGIELYEQGLVKIIDDRTDLLRAEVDTYQVQYG
                     INDEDIRCQCDYFERKQYCQHIAALEYFLKNNQKGKSLSEQLNNQLESKEETKKLTSF
                     GSLFLDSLHMNEDDTTKYRLLASGAKSPFSSDYWWSLKINRLPGEKAYVIRDIKAFIH
                     LVKVEGFYQIGKNYFESLSILQFDQASQELIRFLWRLSTHSDKLDYEWLFPNHARHLR
                     LPAGFFEEGIDLLTGLYEFSFETSSQTYSHLYVRPLEAEAGLFQFTVDVHRSSIELYI
                     KEKNIEYFFNNEYLLYMNTFYHLSLKQQKMVQAIRSLPIEADLAKHIHFDLDDQAKLA
                     ASLLEFRELGQVKAPKSFDIRDFQVTFVFDITEKGELTSQLIFDYGSIQISDKASLDQ
                     LPFASHYKKESSIYRALKRFGLSPQFFAKKALTDPKDWYRFFTEAVPYFESLGRVQLS
                     SKLQDQRLMESPQLTVKREGGLLDISFDFSTVCQTDIEKALATLFSDRSYFVNQSGKL
                     VVFDEETQKISRSLQELRAKQLANGHLQLEGIAATQLSHLFSDLSSVHFSEELETLIK
                     DLQHPDRFELGELAVKAKVRDYQLQGIKWLSVLDKYGFGGILADDMGLGKTLQIIAFL
                     SSRLTETSKVLILAPSSLIYNWLDEFSKFAPQIDAAVSYGLKPARDALIQEGHQVTIT
                     SYSSFRQDLETYQANDYDYLILDEAQMIKNAQTKIAQSLRAFDVKNCFALSGTPIENK
                     LLEIWSIFQIVLPGLLPSKKAFLKMEARDVSRYIKPFVMRRKKEEVLPELPELIEMNY
                     YNEMSDGQKAIYLAQLRQMQERLSAATDDDINRSKLEILSGITRLRQICDTPSLFMDY
                     QGGSGKLDNLRTLLLQIKENGHRALLFSQFKGMLALVKQEMDQLGLSSYTITGSTPAN
                     DRQEMTRAFNNGSKDAFLISLKAGGVGLNLTGADTVILIDLWWNPAVEMQAISRAHRI
                     GQEDNVEVYRLITRGTIEEKILELQENKRHLITTVLDGKQGLASMSVEEIKEILGLQP
                     "
     gene            32537..33130
                     /locus_tag="TVB59_000491"
     CDS             32537..33130
                     /locus_tag="TVB59_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009429.1"
                     /translation="MTKHAFPLVADGEPIIESARQMALYENEDLITNIAGSYQDKHYD
                     DIIRDHQFAEKTPVVSKGSLHHSPVVDEDHSYAQKARRQAKQDVKEKRQAYIAKNMAY
                     SPKQASKKGQSGAFSSKKPATELSRFTEKLNQESYILAELPRQYKEPQNTSQAAVKKN
                     NYDFLKRSQIYNHQEDRDHREKTIAQELNLSRFEDIK"
     gene            33174..34505
                     /locus_tag="TVB59_000492"
     CDS             33174..34505
                     /locus_tag="TVB59_000492"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEL1009430.1"
                     /translation="MSKTYHFIGIKGSGMSALALLLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFSEDNISPDMELIAGNAFREDNNSEVAYAMRHQLPFKRYHEFLGEFMKQ
                     FTSLGVAGAHGKTSTTGLLSHVLKHMTATSYLIGDGTGHGAADARYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTGLDDVFNAFNDYAKQVKKALFVYGEDEELRKISSPA
                     PIYYYGFEDTDDFVAFDITRTTNGSDFKVKHKGHAIGQFHVPAYGRHNILNATAVIAN
                     LFIAGFDMKLVAEHLKSFSGVKRRFTEKVINDTIIIDDFAHHPTEIIATLDAARQKYP
                     NKEIIAIFQPHTFTRTIALLDDFAHALNEADSVYLAPIYGSAREVDKGDVKVEDLAAR
                     VERPAKVISVDNVSPLLDHDNAVYVFMGAGDIQLYERSFEELLANLTKNNQ"
     gene            34553..35035
                     /locus_tag="TVB59_000493"
     CDS             34553..35035
                     /locus_tag="TVB59_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1009431.1"
                     /translation="MLIRHVNQTDWEIIADIEQANFSPQEAVAANVIKERAELISDTF
                     LVAVIANQFVGYIEGPVIAEPRLEDHLFHGVTKNPARGGYIAITSLSVAPGYQKQGIG
                     TALLAAMKDLAVAQDRLGIILTCHDYLIPYYEMNGFQDQGLSASKHGGSVWYQMLWQP
                     "
     gene            35144..36718
                     /gene="mltG"
                     /locus_tag="TVB59_000494"
     CDS             35144..36718
                     /gene="mltG"
                     /locus_tag="TVB59_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEL1009432.1"
                     /translation="MALTDFKDDEQRRQQQKSFKEKILAELEKANQIRKEKEEELFKK
                     DLEVQEAARRTAQLYAEYKRQEALSNNPKQASDIAAASQETTSTASTAHTSAIKLEET
                     AVATGDQALSPPEEPALSESLLKEEASVEGQTKKGGPVRRKTSKRQQTDRMAKKISTV
                     LISSIVAIIVVIGLAGTAYVYSALNPVDKNSDDFVQVEIPAGSGNKLIGQILEKEGLI
                     KNSTVFSFYTKFKNFTNFQSGYYNLQKSMSLEDIAQALQEGGTAEPTKPVLGKILIPE
                     GYTIKQIAKAIETNSRAKNRSKAKTPFHSKDFLNLVTSDAFIQEMAKKYPKLLGDLPS
                     KEVATYQLEGYLFPATYNYYKETTLKDLAEEMIAAANANLAPYYEAIAASGKTVNEVL
                     TLASLVEKEGSTDDDRRQIASVFYNRLNNGMALQSNIAILYAMGKLGEKTTLAEDAAI
                     DTTINSPYNVYINTGLMPGPVDSPGLAAIEATINPAATDYVYFVADVRTGEVYYAKTF
                     EEHSANVEKYVNSQIQ"
     gene            36791..37273
                     /gene="greA"
                     /locus_tag="TVB59_000495"
     CDS             36791..37273
                     /gene="greA"
                     /locus_tag="TVB59_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEL1009433.1"
                     /translation="MAEKTYPMTAAEKEQLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYDAAKDEQAFVEGQISTLETKIRYAEIIDSDAVAKDEVAIGKTVVVQEVGTQT
                     TDTYHIVGAAGADIFSGKISNESPIAQALIGKKTGDKVKIESPAATYEVTIISVDKTQ
                     "
     gene            complement(37514..38434)
                     /gene="yidC"
                     /locus_tag="TVB59_000496"
     CDS             complement(37514..38434)
                     /gene="yidC"
                     /locus_tag="TVB59_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003105894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEL1009434.1"
                     /translation="MKLKTNRILFSGLALSVLLTLTGCVGRDAKGHPEGIIWDYLGKP
                     VSFLIDYFANSTALGYGLAIIVVTIIVRTIILPLGLYQSWKASYQSEKMAYLKPFFEP
                     INQRIKNATSTEEKMAAQTELMAAQRENGVNPLGGIGCLPLLIQMPFFSAMYVAVQFT
                     KGVSTSTFMGIDLGHRSVLLTAVIAALYFVQSWLSMMAVPEEQREQMKAMLYTMPIMM
                     IVMSFYLPAGLGLYWLVGGFFSIIQQLITTYLLKPRLRKQIAEEFAKNPPKAYKSHQP
                     RKDVTAEKQALSTSKRTKLNRNAGKQKKRR"
     gene            complement(38517..38795)
                     /locus_tag="TVB59_000497"
     CDS             complement(38517..38795)
                     /locus_tag="TVB59_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000755490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEL1009435.1"
                     /translation="MKKVRLIVSGRVQGVGFRYSTYALALEIGDIYGRVWNNSDGTVE
                     ILAQASDPAKMTRFIQEIRKGPSKWAKVTYVDVNPSHFEDFHDFRISN"
     gene            39088..39825
                     /locus_tag="TVB59_000498"
     CDS             39088..39825
                     /locus_tag="TVB59_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEL1009436.1"
                     /translation="MIITSKANHLIKQAKKLLQKKHRKHSYLIEGWHLFEEAQRSGQE
                     LIHIFVLEEMAERLSGFDQVVIVSPEILKELTSSPNPQGIIAEVKLCQQALPTSYAGK
                     YLILEDIQDPGNLGTIIRTADAAKFDGVFLSEKSADVYNQKTLRSMQGSHFHLPIWRT
                     DIYQVSQVMQQQKIPVLATTLSQDSIDYKDLSARSSLALVLGNEGQGISPEMAALADQ
                     LIHISMPGQAESLNVAVAAGILIFSLI"
     gene            39864..40364
                     /locus_tag="TVB59_000499"
     CDS             39864..40364
                     /locus_tag="TVB59_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEL1009437.1"
                     /translation="MHYTEDTEYMEHVGHLIAHPRFQRLGDIVQHHHSTRLEHSVNVS
                     YSSYRLAKRLGLDAKSTARGGLLHDFFYYDWRVTKFNKGHAWVHPRIAVRNAKKLTAL
                     NKKEEDIILKHMWGATIAFPRYKESYIVTFVDKYWAVKEAMTPLRQKWTNRRFLRRKT
                     LQSHNH"
     gene            40383..41072
                     /locus_tag="TVB59_000500"
     CDS             40383..41072
                     /locus_tag="TVB59_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEL1009438.1"
                     /translation="MNDNVIYTQSDAGLSHFFAKVYSLVGMGVGLSAFVSYLMLFPFR
                     QNLVSIVLDHPMVYYGAAIVELVLVFVASGAARRNTPAALPLFLVYSALNGFTLSFII
                     AAYAQTTVLQAFISSAAVFFAMSLLGVKVKRDLSGIRKAMFAALIGIIVASLVNLFIG
                     SDLMSYVISLISVLIFSGLIASDNQMIKQVYQASNGQVGDGWAVAMALSLYLDFINLF
                     ISLLRLLGRND"
     gene            41466..41708
                     /locus_tag="TVB59_000501"
     CDS             41466..41708
                     /locus_tag="TVB59_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEL1009439.1"
                     /translation="MSTAIWILLIIVALTAGLFGGIFIARKQIEKEIGEHPRLTPEAI
                     REMMSQMGQKPSEAKIQQTYRNIVKQSKAAMTKGKK"
     gene            41888..42682
                     /gene="racE"
                     /locus_tag="TVB59_000502"
     CDS             41888..42682
                     /gene="racE"
                     /locus_tag="TVB59_000502"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEL1009440.1"
                     /translation="MDNRPIGFLDSGVGGLTVVSELMRQLPHEKIIYIGDSARAPYGP
                     RPAEQIREYTWELVRFLLTKHVKMIVFACNTATAVAWEEVKEALDIPVLGVILPGASA
                     AIKATSGGKVGVIGTSMTISSGIYQEKIQLLAPTVQVTSLACPRFVPIVESNEISSSV
                     AKKIVYETLAPLVGKIDTLVLGCTHYPLLRTIIQNVLGPQVKLIDSGAECVRDISVLL
                     NYFEINGSRDDEHRRHHFYTTAGSDSFQAIASAWLNQTIDVEHVTL"
     gene            42679..43668
                     /locus_tag="TVB59_000503"
     CDS             42679..43668
                     /locus_tag="TVB59_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEL1009441.1"
                     /translation="MSDNIYEYKDKDNWFIGKMTGHNLMAGWGVNHELIAKIDDMLGA
                     IAGDVDWESPVGYDVTVIRYASPFALISFVVGMINQKANRALKVVRHSGAILVTENER
                     LLAVHMPDDGVPVADFFGQQADGFGDTILIATRNEGKTKEFRRLFGDMGYRVENLNDY
                     PELPDVAETGVTFEENARLKAETISRLTGKMVLADDSGLKVDILGGLPGVWSARFSGP
                     DATDETNNAKLLHELAMVFDQKDRSAQFHTTLVVAAPGKDSLVVEADWHGYIATKPKG
                     EHGFGYDPLFIVGETGRHAAELAADEKNKLSHRGQAVKRLMEVFPAWQAKQSL"
     gene            43644..44165
                     /locus_tag="TVB59_000504"
     CDS             43644..44165
                     /locus_tag="TVB59_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEL1009442.1"
                     /translation="MASKTIIVMSDSHGDREVVAAIKGRYLGKVDAIFHNGDSELESS
                     DPIWEGIHVVAGNCDHDSGYKDSLVTSFDGLTIAQTHGHLYHINFTWDRLDYFAQETG
                     ADICLYGHLHRPAAWQLGKTVFINPGSVAQPRGEVNEKLYARVEWTAACIRVDYFTCQ
                     HKSYPSLSKEFKR"
     gene            44162..44623
                     /locus_tag="TVB59_000505"
     CDS             44162..44623
                     /locus_tag="TVB59_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEL1009443.1"
                     /translation="MIAKEFEAFLISHLDSYLIPAEELAIFINTHNADHVMLLLVSNG
                     FSRVPVITKEKQYVGTISISDIMTYQAKRQLTDWEMTQTNIGDMVNTKIETINITSSL
                     TEIMHKLVDFPFLPVVNDDNRFIGIITRKSILKAVNSLLHDFTDEYTITKK"
     gene            44620..45366
                     /gene="xerD"
                     /locus_tag="TVB59_000506"
     CDS             44620..45366
                     /gene="xerD"
                     /locus_tag="TVB59_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEL1009444.1"
                     /translation="MIAFIEPFLASKSLANNSQQSYRYDLRQFCQQVGQRINPETLAL
                     YQQSLSGLTVAAKKRKLSTVNQFLYYLYQQKALTDYFKMDDRIEASFSLKPQLTRLDT
                     SAFYAETAFLKGQLIALLILELGLTPSEIAGLRLADFDLGLQVLRLQSHRGIRVMTLS
                     KALLPFLEKATEAQQLYLFDHDAKPFSRQWFFNQLRDFLESIGCAELSAQSLREQFIL
                     NEKAAGKSIIEVAQLLGLKSPITLEKYYKM"
     gene            45366..46073
                     /locus_tag="TVB59_000507"
     CDS             45366..46073
                     /locus_tag="TVB59_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEL1009445.1"
                     /translation="MDIKVKDFEGPLDLLLHLVSKYEVDVYQVPIVEVIEQYLAYIET
                     LQAMRLELAGEYMLMASQLMLIKSRRLLPKLVDKEPDEEDLEQELLGKIEEYSRFKAL
                     SQELASQHDKRALLFSKPKQELIFEQAVLQKDKTVMDLFLAFSQLMAAKQEAFKYNHT
                     VIERDDYRIEDMMELIEARLELEQELTLTDLLKHCDHLNEAITLFLASLELIKRQLVG
                     IEQTSHFGQIVLRKEIQ"
     gene            46070..46609
                     /locus_tag="TVB59_000508"
     CDS             46070..46609
                     /locus_tag="TVB59_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEL1009446.1"
                     /translation="MTYLSQLEALLFVAGEEGLSLRQLASLLELTPTALQQQLDKLSQ
                     KYKEDKESGLCLIESSRTYKLVTKECLAPLLKDYAKAPINQTLSRASLEVLSIVAYKQ
                     PITRIEIDEIRGVNSSGALSKLVAFGLVQEAGKKEVIGRPNLYATTDYFLDYMGINHL
                     EELVDISSIAVEEQETTLF"
     gene            46846..47568
                     /locus_tag="TVB59_000509"
     CDS             46846..47568
                     /locus_tag="TVB59_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEL1009447.1"
                     /translation="MRINKYIAHAGLASRRKAEELIKRGLVTLNGQVITDLATTVKSG
                     DLVEVEGIPIYNEEKVYYLLNKPRGVISSVSDDKGRQTVIDLLPQVKERIYPVGRLDW
                     DTSGLLILTNDGDFTDKMIHPRNEIDKVYLARVKGVVTKESLRPLTRGVVIDGKKTKP
                     ARYRIIRVEPDKNRSIVELTIHEGRHHQVKKMFEVVGHLVDKLSRTQFGSLDVRGLKP
                     GEARRLSKKEVSQLHHLASTRK"
     gene            47565..47843
                     /gene="yidD"
                     /locus_tag="TVB59_000510"
     CDS             47565..47843
                     /gene="yidD"
                     /locus_tag="TVB59_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEL1009448.1"
                     /translation="MIKALLIAPVRAYQKYISPLFPPSCRYQPTCSAYMITAIEKHGA
                     KGVLMGLTRLLRCHPFAAGGEDPVPDTFSLKRHFITHEKIQDFDQKTD"
     gene            48002..48550
                     /locus_tag="TVB59_000511"
     CDS             48002..48550
                     /locus_tag="TVB59_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEL1009449.1"
                     /translation="MKQEIINRQYREKDSQNHVVLFQPQIPQNTGNIARTCAATNTPL
                     HIIRPMGFPIDDRKMKRAGLDYWDKLDIRFYDHLDEFLAQCDGSLHVISKFADRVYSD
                     EAYNDRQSHYFLFGREDTGLPEPFMRQYADRALRIPMNDEHVRSLNVSNAVCMIVYEA
                     LRQQAFKGLELSHTYEHDKLKS"
     gene            48929..49360
                     /locus_tag="TVB59_000512"
     CDS             48929..49360
                     /locus_tag="TVB59_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009450.1"
                     /translation="MIVYLKQHKNYWKLVSIAALIIILGGILTMNWLNGDRDNKGENN
                     YYQVEKDLAMEIVSEFEGVKEISFLSPVQSKETGYWGTTATINKTNEISYSFSMTFSG
                     KLDDYSYYYDKCFKLVKRHKKLTLSQVDLTDIDIKYSKGGK"
     gene            49575..49988
                     /locus_tag="TVB59_000513"
     CDS             49575..49988
                     /locus_tag="TVB59_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009451.1"
                     /translation="MTVKKKVIILLGMVAILVMGGIFMFSYNQNQAKMLERQFNHEQK
                     RIVLYLLNHYSGINEIEFNDIENNSTTGSKNVLLTINNKIKMEVTFFNLNDDTDNYVI
                     SWNGKLSLIDKNPITHLSSIDKIKVKYWSNNDSNR"
     gene            49972..50226
                     /locus_tag="TVB59_000514"
     CDS             49972..50226
                     /locus_tag="TVB59_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009452.1"
                     /translation="MIVTDKNYNDIADGVYKVDAGKVIRPWRNGKTFKTNGKDYRVLK
                     TEDNPDNGMQAIAVAPIKGSEVGKSHIMIVYVKSSYWLAS"
     gene            50245..50643
                     /locus_tag="TVB59_000515"
     CDS             50245..50643
                     /locus_tag="TVB59_000515"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009453.1"
                     /translation="MKKQQSKRRKLIGIVALITILGGILTMNWFNDEKLNRERREQER
                     AAIYFSNTYENIHKIKIIGIDKNLKTGSMNKATIVNSKYYISVTFMGGEIYTGVEQAS
                     KDNEEFLNRRKKAENKTTLSKDIEVIYKEK"
     gene            50646..>50812
                     /locus_tag="TVB59_000516"
     CDS             50646..>50812
                     /locus_tag="TVB59_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009454.1"
                     /translation="MVSDKDYNKLSEKVYDVDANKVTISVRKNTDILNRYVKILKAED
                     TPDNGMQAMAVV"
BASE COUNT        14825 a         9313 c        11914 g        14760 t
ORIGIN      
        1 gtttgctttg aaagaggaaa cctgctttcc cttctttttc atttgatttt gaatgctatt
       61 tctggtgaaa tatggtaaaa taaaaagtac taattatttt ggagatgaaa tgagtgtcga
      121 tgattatagg ccgacctatg cggtagaggc tgtttatgat ttaagagcaa atgatttact
      181 gcgtcaaggt attacagctg tcttggtgga tttagataat accttaatcg cctgggataa
      241 tcctgatgga actccggagg ttcgtgcttg gttagatgag atgacgattg cagatattag
      301 tgtggtggtt gtgtcaaata acacgtattc acgtgtggag cgtgctgttt cgcggtttgg
      361 tgtggatttt attgctcgtg cgatgaagcc ttttgcctat ggtattaata aggctattga
      421 tcgttatggc tttgatcgtg atgaggttat tatggttggg gatcagctaa tgactgatat
      481 tagagctagt catcgggcag ggattaagtc tgtcttagtg aagcccttag taacatcaga
      541 tgcttggaac actaaggtta atagatggcg tgagcgtcgt gttttggcaa aattggaaga
      601 aaaatatgga aggctagtat atcaaaaagg gatttaatgg aagaattatt ttgtatcggc
      661 tgcggtatcc agattcaaac aacaagaaag caagaggctg gctttacacc tgctgctgct
      721 ttggtaaagg gaattgaagc tagggagatt tactgtcaac gctgctttag attacgtcac
      781 tacaacgaca ttacagatgt tcatattact gatgaagagt ttttgaggct gctccatgag
      841 gtgggagata gtgatgcctt ggtcgttaat gtgattgaca tttttgattt taatggctca
      901 gttattccag gcttatcacg ctttgttgct ggaaatgatg tgttattagt tgggaataaa
      961 aaggatattc ttccgaagtc tgttaaggac agcaaggtga cacagtggtt gacagaaaga
     1021 gctcatgagg agggcttgag acctcttgat gtcctgctga cgagtgcgca gaataaatat
     1081 gctattaaag agctgattga gcggatcgat caattgcgcc aagggcgaga tgtctatgtt
     1141 gttggggtga ctaatgttgg aaagtcgacc ttgattaatg ccattattca ggaaattact
     1201 ggggataagg atgtgattac aacgtcacgc tttcctggga ccactcttga taaaatcgaa
     1261 attcctttag atgatggtag ctttatcttt gatactcctg gtattatcca tcgtcaccag
     1321 atggctcact atttgtcagc taagaatttg aagtttatca gccctaagaa ggaaattaag
     1381 cctaaaacct accaattaaa tccggagcaa acgctttttt taggtggctt ggcgcgattt
     1441 gattttatta gtggtgaaag acaaggcttt acagcttatt ttgataatca attgctcctc
     1501 catcggacaa aattagaggg tgcagatgct ttttatgaca agcaggcagg gcaactgctg
     1561 actcctcctg ataaaaagga gcttgatgat tttcctaggt tggttcgtca tgaatttctg
     1621 ctggatcaaa aagtggacgt tgttttttct ggtcttggtt ggattcgtgt taatgctaat
     1681 aaggaaactg caactaaggt ggcggcttgg gctcctgatg gtgttgcagt agtcgttcgc
     1741 aaggcgatta tttaataaat aaaaagaaaa gtggaataaa aatgcttaca agtaaacaaa
     1801 gagccttttt aaaggctgag gcccatagtc ttaaaccgat tgttcagatt ggtaaaaatg
     1861 gcttgaatga tcagattaaa accagtattc gtcaagcctt ggacgctaga gagctgatca
     1921 aggttactct gttgcaaaat actgatgaaa cgattcatga ggtggcagag attttagaag
     1981 aggagattgg ctgtgatacg gttttaaaga ttggtcggat ccttattttg tttaaggtgt
     2041 cagctaaaaa agacaatatt ttgtttaagg tgtcagctaa aaaagacaat cgcaagctat
     2101 cagttaaggt caaatcgatc tagcgagagc ttttgctagg ctaagacgtt taggtctgct
     2161 gtgtcagtgc tgacaacatg agtaatggtg atattttgga gaggttatgg ctttagaact
     2221 tttgacgcct tttacgaggg tggaattaga aatggaaaaa aaagatagca atcgcaagca
     2281 ggttggtatc ttgggaggga attttaatcc tgttcataat gctcatttag tggtggctga
     2341 ccaggttcgt caacaattgg ggcttgatca ggtgcttttg atgcctgagt ttaagcctcc
     2401 gcatgttgac cacaaagaaa caattgatga aaaacatagg cttcgtatgc tggagctggc
     2461 tattcaggag acagaaggtc tagcgattga agagattgag cttacacgtc aaggggttag
     2521 ctatacctat gatacgatga agctgttaat tgagcaaaat cctgacgtgg attattattt
     2581 cattattggt gcggatatgg tagattattt gccaaagtgg caccgtattg atgagttgat
     2641 ccatatggtg cagtttgtcg gcgtgcaaag gcctaaatac aaggctggta cctcttatcc
     2701 ggttatctgg gtagatgttc ccttgctaga tatttcctca agcatgattc gtgactttat
     2761 ccaaagtgat cgtcagccta atcatttatt accaaaggct gttttagact atattcataa
     2821 agaaggcctg tatcaatgat gtatcaagat tatgttggct atagacgtga tgagctgtta
     2881 ggaaaaattg ctgagcagat gagcgataag cgctttaagc atgttcttgg cgtggaaagg
     2941 gctgctattc acttggcaga gcgttaccat tgtgatccga ttaaggctgg gttagcagct
     3001 ctactgcatg actatgccaa ggaatgtcct gatgagcttt ttataagctt aattgacaaa
     3061 tatcagctgg atcctgagct tcttaaatgg aacaataata tttggcatgg tatggttggc
     3121 atttataagc ttcaggaaga tttggggtta aaagacaaag gcattttgcg ggcaattgag
     3181 attcatactg ttggcgctgc tgagatgacg atattggata aaattctgta cgttgcagat
     3241 tatattgagg aaggtcgagt gtttcctttg gtggacgaag ctaggagaat agcagagctt
     3301 gatctagata aggcagttgc ctacgaaaca gctcatacag ttgcttattt ggcatcgaag
     3361 gctcagccga tttttccgca aaccattgat acttacaatg cctttgtgca ttatttacat
     3421 gaggaataaa atgagaaaag aagaactttt agaaattgtg attaaggctg ctgatgaaaa
     3481 gcgtgctgag gatatgctag ctcttgatct ggctggctta acaagcctaa cggactattt
     3541 tgttattgta acggcaacca atagtcgtca gttggaggcg attgctgaca atattcgtga
     3601 aagggttaag gaagcaagtg gtgatgctag tcatgttgaa ggaaacagtc agactggttg
     3661 ggtgctgctg gatttgaatg atgtggtcgt gcatatcttc tcagaagatg agcgttatca
     3721 ttataatctt gaaaagcttt ggcatgaggc tccagctgtg gagcttagcc actatttagg
     3781 ataaaaaagc agtcggctct gggctgtttt ttacaataag aaacagaaag gaagttggca
     3841 ttagaggcag gattgcctaa gaggtaagct cttgtagtac ttgctgtgag acgtgttgac
     3901 tgtatcaaat aatatgcaaa agaattatga taccttcgca tcagtttatg atgccattat
     3961 ggacgactca ctttatgata agtggacagc gttttcgctt cgtcatttac ctaaaaacaa
     4021 ggagcatcag aagcttttgg agctggcctg tgggactggt attcaatcgg ttcgatttgc
     4081 tcagtcaggc tttgaggtta ctggcttgga tcttagtcag gaaatgctag aggttgctaa
     4141 aaagcgagct caatcagcta agaagatcat tacctttgtg caaggtaata tgctggatct
     4201 gtcacaggtt ggatcgtttg atgtggtgac ctgctattcg gattcgattt gttatatgca
     4261 ggacgagatt gaggtgggtg atgtctttaa agaggtctat caggttttga atgatggcgg
     4321 tatttttatg tttgatgttc attctattta tcagatggat cacctttttc ctggttattc
     4381 ttaccatgaa aatgctgagg aatttgctat ggtttgggat acctacaagg ctgaggctcc
     4441 acattcagtg gtgcatgagc tgaccttttt tattcaggct gaggacggcc attttttacg
     4501 ctttgatgag gtacatgagg agcgtaccta tgatatcttg acctacgata ttttgctgga
     4561 gcaggctggc tttaagtctt tcaaggttta tgcagatttt gaggatcagg agccaacaaa
     4621 gacaagtaag cgctggtttt ttgttgcaca aaaatagctg tggctaagac aggtcagcga
     4681 gcggttttgt ggtttagtgg ctctgtattg agtctgtggc aggtcttgat gataatagga
     4741 atagatgcga aaggtaggac aatgttatga ctgtcactgg tattattgct gaatttaacc
     4801 cttttcatta tgggcatcag tacttactat cacaggcaaa ggggctaaaa attgttgcga
     4861 tgtcggggaa ttttgtgcag cgaggggagc cggcacttgt ggataagtgg gtacgcgcgc
     4921 aaatggcatt ggaaaatgga gctgaccttg tggttgagct cccttttctg gtttctgttc
     4981 aatctgcaga ttattttgct cagggagctg tggatatctt gatgagactt ggaattgata
     5041 cccttgcctt tgggactgag caattgcttg attaccagaa gctgtctagg ctatatagtg
     5101 aacaagcaga gcacatgact gcttatttgg ccaccttacc tgatcatcta tcttatccac
     5161 aaaaaacaca aagcatgtgg gaggcctttg caggccttag cgctactggt gataggccaa
     5221 accatctttt agcattatcc tatgtcaagg ccagcgcagg aaaaaagctg caattgcagc
     5281 cgattaagcg gctgggggca ggctttcatt cagaagccaa ggatcaatgc ttgtcatcgg
     5341 cgacagcaat tcgaaagcat atcgctgaca gagcctttgt ggaaaaatca tcacctaatg
     5401 cagctcttat tttgagggct cctcaggtga cttgggagca ttattttccc tttttaaaat
     5461 atcacattct gacagctcca gatttaacac agttttttca ggttaatgat gagctagcta
     5521 gtagaatcag cgcagctatt cggagtgtag cgacggtaga tgagctagta gaggcggttg
     5581 caaccaagca ctataccaag gcaagggtga ggcgtgtgtt gacctatatc ttggttaagg
     5641 ctgtggaagc cccattgcca gaaggcatac atgttttggg cttttcaaaa aaaggtcagg
     5701 ctcaccttaa aacaataaaa gcttctgtgc cgctaatcag tcgtattgga gctaagcctt
     5761 gggatcagtt gactcaacga gctgacactg tttatcagct gggacatacg gatatgccag
     5821 agcagacttg gggatgtgtg ccgataaggc cagaggcgat gaattgagcg ttactagaag
     5881 caaaccactg tctttgtatg acacgcttag aggaccagca agagcttcta agaagttcgg
     5941 gtaggcccta tagtcagttg gtaaaggtgt tattagagta gttcaggtga ctctttgctg
     6001 gtataaaggt cagatagact gcctttgctt gctaagctgt ttttcattgc tgataagaag
     6061 gatagttagc aagaactgtc agctcatgga agcttatcat ttaagatcaa aaaagttaag
     6121 tttgttcttg actctctccc tacgtgatag tctatacttg ttgttgaggt ggaaatagcc
     6181 atactagttg gtgctctttt gacctcacta aggaggaata ccatgaaaac cgtaaaagag
     6241 gttagtcaat tgacagggct tagtgtacgc accttgcatg agataggcct gctgcctcct
     6301 acaatggtgg gagaaaatgg ttatcgcttt tatgatgctg ctgccttgag acgtctacag
     6361 gacatcttac tgtttcgtga gctggcattt cctctaaaaa cgattaaaca attgctggac
     6421 agccctagct atgaccaaca agcagccctt gctgctcaga ttaagatgct agagctacgc
     6481 aaggctcatt tagaaaaggt tattgctcat gctaggactt tacaaaaagg agaagaaacc
     6541 atgacctttg acatttatag taagtcacag ctagaagcct ttcaactaga ggctaaggag
     6601 cgttggggag agacagaggc ctatatggct tatgaggcca aagtcaatca gcctagcgca
     6661 gagcagctta tcaaggatat gggggagatc ttttcaatct ttggtcgtat gctggatcag
     6721 cctgtagcag agctagcagt acagcagcag gtaaaggctc tgcaggatta cattagtcaa
     6781 cacttttacg attgctcaac tgagatctta tcagctcttg gttgtatgta tcttgaggat
     6841 gaccgcttta gagcagctat tgatcatatg ggtggtgcag gaacggcagc ctttgtcagc
     6901 cgagctatta gctattattg tcagcactaa gctgctaagt gcatatcact ggctgctatt
     6961 cctaatttac gaaccctttt gaaagtgcta taatgataga gttaaagcta atttaactct
     7021 gcttattcta aaaagagctt aatcaaaatt gtattttaga ggagaatcca atgggacgta
     7081 aatgggcaaa tattgttgca aaaaaaactg ctaaagacgg tgcaacatca aaggtttatg
     7141 ctaagtttgg tgttgaaatc tatgtggctg ctaagcaagg agagcctgat cctgagttga
     7201 atacagccct caagtttgtc attgatcggg caaagcaggc acaggtgcca aagcatgtta
     7261 ttgataaagc cattgataag gcaaagggta atactgatga gacctttgtt gagggacgct
     7321 atgagggctt tggaccaaat gggtcaatga ttatcgtaga caccttgacg tcaaatgtga
     7381 accgtacagc tgccaatgtt cgtgctgcct atggtaaaaa tggtggtaat atgggagcgg
     7441 ctggatcagt ttcttactta tttgataaaa agggggttat cgtttttaag ggcgatgacg
     7501 cagacagtat ttttgagttg ctcctagagg ctgatgttga tgttgatgat gtagaggcag
     7561 aagacggatc aattactgtt tatacagcac caacagatct gcataaggct attcttgctc
     7621 ttcgtgaatc aggtatatca gagtttcagg tgactgagct tgagatgatt cctcagtctg
     7681 aggtaactct tgagggggat gaccttgctg tttttgaaaa gctggttgat gcccttgaag
     7741 cagatgatga tgtgcaaaag gtctatcata atgtagctga tgtctaagcc ctaagactat
     7801 catgtaaaca gagccgagat ttctcggctc tgttcatttt cctataatcg agctctgtag
     7861 aggctgagta tgactatctg ccttttatgg taacagctga cgtagtagct gatcgtcaca
     7921 tggtgctgct ttagcagagt tcaatcatta gtatcttatg ataaaaaatg ataaactaat
     7981 cttatgaatc ataaaggagt agaggacaat gacaataaaa cgttatttag gtttagctgg
     8041 cttggccgta ctgtctgtgg gtatgctagc ggcatgtggc acaaaggaaa aatcagcttc
     8101 gagcacaaag gacacaccaa aagaggttat ctttgcgaca gttggaacaa ctgccccctt
     8161 ctcatttgaa aaggaaggac aattgacagg ctatgacatc gaagtggcta aggctgtgtt
     8221 taaagatgct gagaagtaca agcttcaatt taagaaaaca gaatggtcat ctatttttac
     8281 gggcttagac tctggaaaat atcaaatggg cggcaacaat atttcataca ctaaggaacg
     8341 ctcagtcaaa tatttgtttt cttatccaat tggtgcaact ccgtcagtgc tagttgtgcc
     8401 aaaggatagt gatatcaagt cttatgatga tattaagggt cattcaacac aggtggtgca
     8461 gggaacaacg actgctgctc agctaaaggc cttcaacgaa gagcatgctg ataatcctgt
     8521 tgagctaaag tttaccaacg aaaccatcac tcaaatgcta accaatctga atgagggcaa
     8581 ggctgatttt aagatttttg atgccccaac ggttaatgct atcattgata atcaaggctt
     8641 agatcacttg aaaacaattg agctggcaac aagcgagcag ccctttatct actttatttt
     8701 tagtcaagat caagaggagc tacaggcctt tgtcaataag cgcttagagg agctgacagc
     8761 tgatggcaca ctcagtaaaa ttgctaaaaa gtatctaggt ggcgattatg ttccagctaa
     8821 gcaggatttg aagcttccta cagcaaaatc ctaaattggc tgaaagacca acaacgatat
     8881 aagcgactat ttggcttaaa accaagctgt tagaaggctt gcttttaagc ctttttaaat
     8941 gcctttgttg cctactaggg cttttaaagt aacctagtgt ctagggcagc agctattaag
     9001 atctgttgcc ttatttcgag ggtggttttg aggtaaaagg tctgtagtaa gagccttgac
     9061 ttaattaatg cttgcttggc tagtctgtca gttggtttag gtttggtgtt ttgactagag
     9121 attatagcta atggctatac cttatcctaa aatttaccaa tttgaatgcg agagctattt
     9181 cgtataaaat aaactcattg aaaaaaagaa attgaggaac aaaatatgaa tattaaaaaa
     9241 gctgtcggct ttgttagcct tgctcttgct tcaatagctc tagtagcctg ctctggtaag
     9301 caggacgaca aaaatacctt gaccattggg gtaatgacta aaacggcatc tgatcaagcc
     9361 agatgggata agattgaaga gctgctgaaa aaggataaga tcactctaaa gtataaagag
     9421 ttcacagatt attctcagcc caacaaggca gttgctaatg gtgaggttga tatcaattca
     9481 ttccagcact ataacttttt ggataattgg aataaggaaa ataaggcaga tttgaaggct
     9541 attgctgaaa cctatatcag tccgattcat ctcttttcag ggactagtca agacggtaag
     9601 gctaaatacc agtcagtaga tgagcttcca gatggtgcgc aaattgcagt gccaaacgat
     9661 gcaacaaatg aaagccgtgc cctgtatgtg cttcaagcag ccggcttgat caagctcaat
     9721 gtgtcaggtg ataagctggc aaccattgca aatattacag aaaataagaa aaagctagat
     9781 attaaagaat tagatgcgag tcagacagca cgtgccttga cgtcagctga tgccgctatt
     9841 gttaataata gctatgccgt tcctgcgaaa attgatttta aaacctctct ttttaaggaa
     9901 aaggctgatg agaatgccaa gcaatggatt aatatcattg ctgctcaaaa ggattgggaa
     9961 aagtctgcta aggcagacgc gattaaggca ttaatcaagg cctaccatac agatgctgtg
    10021 aagaaggttg tggataaaac ctcaaatggt gttgacgtcc ctgtatggta agggataata
    10081 ggtaatatta gtaacaggag gattgaggcg tgtgaagcac gccctttctt atattagggg
    10141 gaaaacacat gacaaaaacg gatcagcagt acttaacaag gctttgggag gatcagctca
    10201 cacaggatta tcttgtgtcg ttggggcaat tgattgccag taggtctatt tttgctcaag
    10261 gtatcggctt agaagagaca gcagcctacc taaaggagct gtttgctcag gctggtgctg
    10321 aggctattgt tgataagact tatgcagctc cctttgtcct agcacgcttt aatagctcta
    10381 ggccagctgc taagacactg atattttaca atcattacga tacagtgcca gcagatagtg
    10441 atcaaaagtg gacgagtgat ccctttacct taacagagcg tgatggctat ttgtttgcgc
    10501 gcggcgttga tgatgacaag gggcatatca ttgcgagatt gacggctgtc gtcaggtatc
    10561 taaaggagca tgcagacctt ccgcttaata ttgtctttat gatggaggga gctgaggagt
    10621 cagcttcggt agatttagat cggtatctgg ctaaatacgc agaccagcta aagggagcag
    10681 agcttttgat ttgggagcag ggcattcgta atgagcatga tcagcttgaa ataactggcg
    10741 gcaataaggg gattttgacc tttgagatgt cagtagatag tgctcgttgt gatattcatt
    10801 ttaaatatgg tggtgttatc gagtcagcag cctggtattt gcttcaggcc ctatcaagcc
    10861 tgcggaacca tcgtggggaa ttgctggtgc ctggtattta tcaaaaagtc gttccgccaa
    10921 ctgagcgaga gctagattta gttgagacct atgcaattga gaatgctcaa gctctaaaaa
    10981 agctttacgg actggagctt cctatgttac aatcagagcg tcgtcaattg ttagcagctt
    11041 attactttca gccctccatt aacattcaag ggctgtggac tggctatcaa ggacaaggag
    11101 ttaagaccat cattccttca caggctactc ctaaaatgga ggttcgtttg gttcctggct
    11161 tagagcctga gtatgtcttt gatcagatta ggtcttattt gctcaataag ggctttgacc
    11221 agatcaagct gacctatact ttgggtgaga tgagctatcg gagtgatctt tcatcgtctg
    11281 ctattagtca gctgattgca gcagctcagc ctttttaccc taaggggcta tctcttttgc
    11341 cgacatcggc aggaacaggc cctatgcata ctgtttttga agccctgcag gttccgattg
    11401 ccgcttttgg cttagggcat tctaatagtt gtgatcatgc aggtgatgaa aacattgcta
    11461 ttgtagatta ttgtcggcat attgcattaa tagaggagtt aataacatct tatgagtgaa
    11521 ccaatgattc aattagatca tattgatatt acctttcacc aaaaaaaacg tgtgattgaa
    11581 gctgttaagg atgtaacgct tcatatcaac caaggggata tttatggcat tgttggctat
    11641 tctggtgctg gcaaatcaac cctagtgcgt gtgattaacc tgctgcagca gccaacaaag
    11701 ggaagcatta caattgatgg ggagctgacc tttgatcaag gcaaggttca gctgtctgct
    11761 aatagcctac gtgagaagcg tcgtgatatt ggcatgattt ttcagcattt caatcttatg
    11821 gcacaaaaaa cagctaagga aaatgttgcc tttgctctgc gccattctcg attgcctaag
    11881 gctgaaagag aaaggaaggt gactgagcta ttagaattag taggcttatc tgagcgtgca
    11941 gacaattatc cagcacagct gtctggtggt caaaagcaga gggttgctat tgcgcgtgcc
    12001 cttgccaatg accctaaaat attgatttct gacgaggcca cctcagcgct agatcctaaa
    12061 acgaccaagc agattctcgc tcttttgcag gaattaaacc gcaggctagg cttaacgatt
    12121 gtcatgatta cgcatgaaat gcagattgtc aaggatattt gtcatcgtgt ggctgttatg
    12181 cagcagggaa ccttgattga agaaggcagt gttttggata tcttctcaaa tccaagagag
    12241 cctttgacgc aggagtttat caagacagcg actgggattg atgaggcact tgagaaaatt
    12301 aaccagcagg atattgtcaa ggagctacca gctaatgcta ttttagctca gctcaagtat
    12361 gcagggacat cgactgacga gcctttactt aaccagattt atcgccagtt tgaggtgacc
    12421 gctaacattc tttatgggaa tattgaaatc ttagatcagg taccagttgg tgagatgatt
    12481 gttgtttttg aaggtgcagc agcaagtatt gaggcggcag aaaaagcctt gcatgaggct
    12541 ggcgtcgatg tcactatttt aaagagaggg gcttaaatgt tagaattgtt tcaggcttat
    12601 ttgccaaatg tttatgagct tggctggtct ggtgatgctg gctggggagt agccatttgg
    12661 aataccttgt acatgacgat cgttccattt attgtaggtg gagctattgg tttatttatt
    12721 ggtcttttgc tggtactgat ggggccagat ggggtgattg aaaatcgact ggtttgttgg
    12781 cttctagata agctcacgtc gatttttcgg gctattccct ttgttatatt aattgctatc
    12841 ctggcaagct ttacttatct gattatgggg acaaccttgg gtgcaaccgc agctctggtg
    12901 cctttgacct ttgcaacctt tccttttttt gcgcgtcagg tccaggttgt tttttcagag
    12961 cttgatagag gtgtgattga ggctgcacag gcttcaggag ctaccttctg ggatattgtc
    13021 agggtttatc tgagtgaggg cttaccagac ctgattcgtg tgtcaacagt gaccttgatt
    13081 tccttggttg gtgagacagc gatggcagga gctattggtg ctggagggct tggtaatgtc
    13141 gcgatttcct atggctataa ccgttttaac aatgatgtga cgtgggttgc cacccttatt
    13201 attctcttgc tgatctttgc gattcaattt attggagaca gcctgacaag gcattttagt
    13261 cacaaataat aaaactgctc agagctttat tagctccaag cagtttttta atgtcatgat
    13321 gctgtagggt gaagtccttt tgtcttgctg atgatgagac ctaagacaaa gcctaggatg
    13381 gaaaagctaa tccagcccat tgaaaattgg ccgagtggaa ccaacctttc aaagaaatag
    13441 gaaagaccat caggcaaggt aaagagcttg gttagctgtg agagggtagc tagggcgtca
    13501 tacaatgctg gaatgatggt aaggccaatc gtcgttctgt agacaagagg ggcattgcca
    13561 aatgactttt ggatcagaac aagaacaatc aaatcgacag tcagtgggta caagaggtac
    13621 aaaataggag atgaccaatt gataataact gacaagccac cgaagtagaa aaaggcagat
    13681 acaagggtaa atagagttgc ccaagcaaca tgtgataccc ttggcattag cttgtggaaa
    13741 tactctgcac ttgaggtgat aagaccggtt gaggtggtca gacaggctag gaaaatcaca
    13801 atcgcaagga aggcttgccc aatgctacct aggtaaaatc gtgaggcgtg gcttaaaatt
    13861 tgtcctccat tgacagcgct gttgtttagg gtaaaatgcc catcaacaaa agggaaaaga
    13921 gattgtgagg tcgcaccgat ccgtcccaca aaaatataaa caaaggctag cagcaaaatg
    13981 gcaatggccc cagagataag ggtgatttta gtgatttcct gatcggtttt agcgccaaat
    14041 tgcttggttg cttcaatgac taatatggca aaaaccaagg aagctaaagc atccatagtg
    14101 ccgtagcctt gaataagacc tgcaataaag ggaacgtcct taaaggcatt gttgatacct
    14161 gctccagcat taaaggcttc gccatagtct ccagctgggt gaacaaagga ggcaatgatt
    14221 aaaatagtaa tcacaaccaa tagcgtcggt gtcagaaatt taccaatgct ttctgctagc
    14281 ttgcttggtc taatagccaa aaagtaggat aagccaaaaa atagcacagc atagatggct
    14341 ttattgatga tgctatctcc taatatcggg gcaatcccaa cagagaagga ggtagcgcct
    14401 gttctaggaa tagcaaagaa aggaccaatg gacaaataca ggattgatga gtaaaggata
    14461 gcataccatt ttgaaattgg ccgagccagg ctttcaacat catcagagcc tgaccttgca
    14521 acagcaatga caccaagcaa gggtaaagac acaccagtca agcaaaagcc aataatggac
    14581 caagggatat tttgtcctga atagatgcca agaaaggccg gataaatgag atttgctgca
    14641 ccaaaaaaga gagcaaacag cataaagcca ataacgatat agacattttt ttctttcatt
    14701 gccttaataa gtctttcttt tgatataaat ttgaagattc caataattta attgaaaact
    14761 cttgaaaata ataacagttg ctattatacc taagtttctg aaagtcgtca acaattatca
    14821 gacgatagat caagctgaga cctaaaaaag cgctgagggg tatctggata aagcagctta
    14881 gcctttattt tacagctttt gagaggactt gctcacctgc tgaatctcta atcaagcctt
    14941 gctagaaaga gtggtccaag gcttggggag ctttgatgag agatttgctg tcttattgat
    15001 gaaagaatct gtcagctagc ttatgatggt ggggctgcag cggtgtataa catccttgct
    15061 tgatttgacg aataactaaa attatattat gataaaaaac atctaacttg agcgaggata
    15121 aataacatga aaagaattcg tgacttatgg gtcaggacca acctgattaa aaaaatagga
    15181 atcggggtcg ttataggact tcttttgggg attttattgc ctgatgtgac agcgattggc
    15241 attttggggc agctttttgt tggggcttta aaggcgatag ctcctctctt ggtttttgcc
    15301 ttggtggcac aagctatctc tcaccaaagg tcaggacagc aaaccaatat gaccttgatt
    15361 attgtgcttt atttgcttgg aacctttctg gcggccttgg ttgctgttat tgctaattac
    15421 ctatttcctc taaccttaac cttaaatact ccggttaata ctgagctttc accaccacaa
    15481 ggtattgttc aggtctttca gacgctttta ttaaagctag tggataatcc tattaatgct
    15541 ttagctactg ccaattatat tggtgtctta gcttgggcat tgatctttgg cttagccctc
    15601 aagtctgttc cttcagattt taagcatttg atcaaaacag cggcagatgt gacctcacaa
    15661 attgtcgttt ggattatcaa tgtcgcaccg attggcatta tgggcttggt cttttcaact
    15721 gtttctgaaa atggcattag cattttgtct gattatgctc ttttaattct ggtcttggtg
    15781 ggaacgatgc tctttgtagc gctagtggtt aaccctttgc ttgcctttgt cctgactcat
    15841 caaaatcctt atcctcttgt ttttagatgt ttaaaggatt ctggccttac agcctttttc
    15901 acaagaagct cggcagcaaa cattccagtc aatttgcagc tatgtgagga cttgggacta
    15961 agtcaggcga cctatttagt atctattccc ctaggtgcaa tgattaatat gggaggagca
    16021 gccatcacga tcaatgtttt gacacttgct gctgtcaata cctttggtat tcagattgat
    16081 tttctgactg ccctgctttt gagtgtggtt gcggctatct cagcctgtgg cgcttctggt
    16141 gttacaggag gctctctcct tcttattcca gtggcatgta gcctttttgg gatctcaagt
    16201 gatttggcta tgcaggttgt cggggttggc tttattgttg gtgtgattca ggattcctgt
    16261 gaaacagccc ttaattcatc aactgatgtc ctctttacag ccattgctga aaatgccttc
    16321 tggaagcaaa agaaggccta gccttataat acagcttatt agtaaaaaaa gaggctggga
    16381 caaaaagagc tgcactttag aaagtcttaa cctaatatac tttatgacct agtctcatgc
    16441 attaaaaaag cgaacaagtc tagttttcgg aatctctgaa aactggctcc atgtcaactg
    16501 tagtgggtga cttatagcta agcacgagag gagacgaagg ttgtcttctc ttttgtgatg
    16561 ttcaaagcga ggaagatgcg ttttttaggc tctataatct ccacagtggc cttacccact
    16621 acagaaatta tagagcctga aaactagact tgttcgttta ttttaggtca gacttttgtc
    16681 ccagacccgt tatgttattt gaggtagcct aggtagtcaa acttttcaaa ggtatgatcg
    16741 ttagcgatag caacaataat ggtgtcagcc tcaagtggtt caaagggctg aacattggtg
    16801 tctagggttt tgacctcttt ttgacgcatg ccaataatat taagctcgta ttttcgacga
    16861 acatcaagct ctgagagcga tttgccctcc cagctcttag gaatggtgaa ttcgatcatg
    16921 gaaatcccat gttctaggta gataatgctc tcaatgtgat ggcgtaagag atttgaggcc
    16981 actcgctttc cagagtctct ttcaggggtg ataaccttgg ttgctccaat gccatataag
    17041 acctcttcaa aaattttgtt tttagccttt gcaataatgg ttggaacccc taatttttta
    17101 cagtgcatga cagctagtac agaggactct agattgtttc ctgatgcgat gacaactgtg
    17161 tcacattgct caacccctac tgcgattaaa aaatccttat cagtaatatc gccaacagct
    17221 gccttggtcg ccaaatcagc aatttctttc acgtggcttt ctctaatatc aatggcaatg
    17281 acatcttggt catagttgct taattctctg gcaacggtgc ggccaaaaat ccccaggcca
    17341 agaacaccaa cagtttttcg ttttaacatg atttctcctt aacccactaa aatatcagta
    17401 gtggcatatt gaatggtttt ttctttacgt tgaattagac taatcaaaac agtaattggt
    17461 ccgacacgac caacaaacat cagcacaata atgattaggc gtcctgcact tgataagtgc
    17521 ggtgtgacgt ccattgatac cccaaccgtt gcaatagctg aaatggattc aaataaaagc
    17581 ggaatagggg cgatatctgg ctctacactt agcagtaaaa tgtagccaat catcaagacc
    17641 gcaaaaaaga aaatcaaaac agtcatggtt tgcttaatgg tcttgttggc gatgatacgg
    17701 ttacgaaagg ttacctcaga ttgaccggaa agctctgcct taaacaataa aaaggtgatg
    17761 gcagcagttg tgattttgat tcctccggca gtaccacctg gagctccacc gataaccatc
    17821 tgaatcatat aaagaatatt ggtaggagcc aaggtatcat tataagaaat agtcgcaaag
    17881 cctgcagttc tcatggttac cgtttggaaa aaggacacca tcagctgctg cggtagattg
    17941 tatctggcaa tagtattgag attgtccttt tccaaaaacc atgataaaaa ggtacctaaa
    18001 acaaggataa ctagggttgt ttgcagcact aagcgtgact gattagaaaa ctttttaaag
    18061 gtgatgccat agcagtgagg cctttcaaag aagtattttt taaaggcagt gcctaaatca
    18121 acccaaacag caaagccaag tccgccagaa ataattaaga aggtgataat agcattgatg
    18181 gtagggttta acacaaagtc ctttaagcta gatgatccta gattatcaaa gcctgcatta
    18241 caaaaggcag agacagccag aaagatactg ttaaagatac catttttcca gccgaaacga
    18301 gggataaagt cagtcatgat aaccaaggca gcaaaggcct ccagtgagaa ggtgacctta
    18361 taggcaaaaa agaggtattt ttttaagtcc ttactgtcac cacgattgag ggcggattgg
    18421 agcaaggttt gatcacttaa acgcattttg cgcttgagtg caaaggtgct gaccgcaatc
    18481 agagtgacca atccaagtcc gccaatttgc atgagcatca tggcaattgt ctgaccaatg
    18541 ccattgtaga catctgcaac aggaacgaca gaaagtccag ttacacagac cattgacacc
    18601 acgttgaaaa aatgatcgag gtaaaccgta ttaggaccat tgctgtagtg ggtaaaaggc
    18661 atggataaca agagactacc tatcaaaatg acaatcgcaa agctaaaggt tagccgctgg
    18721 gtcaccgata aggacttgaa aaatgagcgt ttcatgattc ctcctaataa tatctcatac
    18781 tatcatatca aaaatacatt aaaaaagcta agcagtaacc tagccttaga ctgaagcagc
    18841 cctgtttaca ataggccctt cctaacatgc tccaaaagac aatagctttt tttgacatgt
    18901 caggcttaag cttttagctc agagcttaaa agtgctgagt aagattttat aaagtcttaa
    18961 gggctttagt cattgttgcc acagtagaaa acagaatggc gagctcactg cctagcctat
    19021 gttttttctt gctaggcttc aaagaggctt gatgttttga agcgtcaaaa gtaatcttga
    19081 cagggttcta tatggctaat cgatatcact caaggctagc acttagcttt tgtggtttga
    19141 tcacatgatc attggctgtg gtcatagcgt cagctccctc ctactagcct ctaatggcta
    19201 ataggaggat caagggcaac aaaaaatgtt cagacagcct ttaatcaagg ctgcctgaag
    19261 cagcattcta tagcctctta caatggtttt tattaggaat accggctttt cgagggtact
    19321 tgtttggcgt ttcctttttc ttttcgacaa gagtgatata gcggccatct ccattaggaa
    19381 gttggtaggg ctggtgatca agcaccttag caaaaagtag ctgaagtgcc tttttagctt
    19441 cttctaattc ttggtccgct gcttgtgcct ttaaagcaat cagttttccc ttgattttta
    19501 aaaaaggaat ggtcaactca gacagaatct gcatgcgggc aacagctcta gcagttacca
    19561 aatcaaattg gccacgaaat tgcttgtctt gtccaaaatc ctctgcccta ccatgataga
    19621 aatgtactcc ctctaatcct agctctttag caaggagctg aagaaaatgt atgcgcttat
    19681 tgagagaatc aataatggta acatcaagct ttggaaacat aattttcata ggaatgcttg
    19741 ggaagcctgc tccagcccca atatctaaca gcctgagagg ctcatttgga atatatccct
    19801 gtaaaagcgg agcaacagag tcataaaagt gcttgagata gacttcattt tcttcagtga
    19861 tggctgttaa gttgatctta cggttccaat caaccaaaag cttaaaataa gtgtcgaatt
    19921 gttctttttg atgatttgtc agagcaaatc ctgcttgctc caggacaagg taaaaggctt
    19981 ggggtgtcat atatatcctc tgtttttaat taattgctac tattttagca taaaatagca
    20041 gaaaactgct gaaaagtccc ttcaatactt gctattaaac tgaaaattgc tataattgag
    20101 acacaaagat taaaggagaa ttacaatgcc aatgttttta gtaatagtag cccttatcgg
    20161 tgtgctggtt gtttggctga tggttagcta taatggcctg gttaaagctc gtatgcatac
    20221 aaaagaagct tggagtcaga ttgacgtgca gctaaagcgt cgcaatgact tgattccaaa
    20281 ccttgttgag acggtcaaag gctatgctaa tcatgaagag aaaaccttag aaaagattac
    20341 tagtcttaga tcacgtgtgg ctgatgctac tacaccgcag gccacaatgg cagcctccaa
    20401 tgaattgagc aagcaggtca ctagcctctt tgcagttgca gagagctatc cagacttaaa
    20461 ggccaatagt aatttcctaa aattgcaaga ggaattaacc aatacagaaa ataaaatttc
    20521 ttattcgcgt caattattta atacaacaac atcgcattat aaccttaagc tagaaagctt
    20581 tccgagcaat cttgtggcta aattgtttgg cttcaagcca agtgagtttt tacaggttcc
    20641 tgaagctgaa aaagaggttc caaaggtaga ctttaccgtc tagtctaatg cggctaatca
    20701 aggtcagaag aggacatcaa tgctttatca acaaatttca caaaataaac gacgaactgt
    20761 tatcctgctt tttgcctttt ttgtcttact ggtagtgatt ggcgctgctg ctgggtattt
    20821 actggctgac agctaccagc tgggggctgc ttttgctctg attattggtg ctatttatgc
    20881 ctttagcatg atttttcagt caaccagcct cgttatggga atgaataagg ctaaggaaat
    20941 cacagtaaac gatgctcctg atttctttca tattgttgag gatatggctc tggttgctca
    21001 gattccaatg ccaagagtat ttatcattga tgatccctca ctaaacgcct ttgccacagg
    21061 ctccagccct caaaatgcag ctgttgcggc aaccactggt ctactaaagg tgatgaatcg
    21121 tgaggagtta gaagcagtga ttgggcatga agtcagccat attcgtaatt atgatattcg
    21181 gatatccact attgcagttg ctttagctag tgctgtcaca ctgatttcca gcattggggg
    21241 gcgtatgatg tggtatagcg gtggcaggag acgtgataac gatcgcaacg ataatggctt
    21301 tggcgctatt atgctgattt tctcaatctt gtcactgatc ttggctcctc ttgcggcctc
    21361 tctggttcaa ttagccattt ctcgtcaaag agagtatctg gcagatgcca gctctgtcgc
    21421 gttaaccaga aatccagagg gcatgattag ggctctacaa aagctaagca attcacagcc
    21481 tatgactcat ccagtagatg atgctagcgc agccttatac atcaatgagc ctagaaaaaa
    21541 agaaaagctt agcgctttat ttagtaccca tccgccgatt gaagatagaa ttgaacgctt
    21601 gaagcatatg tgagagcttg agactagctc agctctcatt tttactagcc ataatgttca
    21661 gaaaacatca ttaattaatt gttttgaccc ggacattttt taagactttt atggaaattt
    21721 gggctatttt cataggggtt ttatggttaa acatttgatt gttggcttgt caatacttat
    21781 ttgtatccag acttaatgtt aaaaaaagtt atgaatttgt cataaagcta ttgacaaatt
    21841 cttgatatca tagtaaaaat agattagagt tttattagga agtgttttat aggagaaagc
    21901 atgttatctg tttcagatat tagaaagcga ccggaaggca ttcgctttga gagagagtac
    21961 gatgttaagg aagcgctgct tatacgtgat ccgcaggtta tagatattaa taacgtcaga
    22021 gcttcgggga gagctcagtt tgatgacggc ttgtatctat tagagtatca gctgggctat
    22081 cagattaccc tgccctcgag ccgttccatg gcgcctgttg tcttagatga gatgcagacg
    22141 gttcaggagc tgtttatcga ggaagcagat gtggcaagta agcaggaaat ggttgatgaa
    22201 aaccttgtct tagtcttatc agaggatcag cttgaccttg aagagagtat tattgacaat
    22261 attttgttgg cgattccctt gcaggtattg acagaggctg aaaaggagtc acaaatcttg
    22321 ccgacagggg aggattgggc agtcttaact gaggagcaat accaggccca gcagaaggaa
    22381 aaagcaaaag acaacagtcc ttttgcgggc ttacagggtc tttttgatga gtaaaaataa
    22441 aaattaaaga tgtctgtatt ttttatttga aaaaagaaca gttgtctggt atactttata
    22501 aatatacggc atattagtca ttttgatgac taaatagcaa tacttgatta atacaaaatg
    22561 gatgaatctt gtacatagct gataaggggc tgtgatacag gaagtaagga ttggtgtaat
    22621 gacaaagaaa attttaatta tcgaagatga aaagaatctt gcaagatttg tttcgcttga
    22681 gctacagcat gagggttacg aggtaaccgt cgaggttaat ggtcgtgagg gcttggagac
    22741 agccctagag aaggactttg acttaatcct tcttgatttg atgcttcctg agatggacgg
    22801 atttgaagtg acacgtcgat tgcaaacaga aaaaacgact tacatcatga tgatgactgc
    22861 gcgtgactct attatggacg ttgtagctgg cttggatcgt ggtgctgacg attacatcgt
    22921 gaagccattt gccattgagg aattgctggc gcgtattcgt gctatcttcc gtcgtcagga
    22981 cattgagtca gagaaaaaga ctcctagtca aggcgtttac cgcgacttag tcttaaaccc
    23041 tcaaaaccgc tctgtcaatc gcggtgatga cgagatttca ctgactaagc gtgaatatga
    23101 cctgcttaat attttgatga caaacatgaa tcgtgtcatg actcgtgagg agctcttgtc
    23161 taacgtttgg aaatatgacg aggctgttga aactaacgtt gttgatgttt atattcgtta
    23221 ccttcgtggg aagatcgata tccctgggaa agagtcttac attcaaactg ttcgtggaat
    23281 gggttatgtg attcgcgaga aataattgat ggcaaagcag aaaaaatata agaaaacgtt
    23341 accaaaacgt ttatcgaatc ttttgttcgt tctcttcttt tgcattttct ctgcctttac
    23401 cctactcgct tatatttcaa caaactactt tttgttgaaa cgagaaaagc aaactatttt
    23461 tcaggctgtt aacattgtta gagttcgtct ctctgaggtg gactctaatt ttacgttaga
    23521 gaatttagca gaggttctct ataaaaatga cagaacgcat ttaaagattg atgacgcaaa
    23581 tggtagtcgt attatcagaa gtgaacgaaa tatcaccaac acgctcaatg ccaatgagga
    23641 tatctatgtc tacaatgttg ataagcaaat gatcttcaca acagatgacg aagaggcctc
    23701 gccaggctta aatggaacta ttggtaaggt aaccaaggac cacattgagg agcaatacaa
    23761 gggcttttca atgactcaga aggtctactc taataagaca gggaagtttg taggctatgt
    23821 tcaggttttc catgacttgg aaaactacta catgatcaga gcacgcctct tcttttggct
    23881 tttggtggtt gagctctttg gggttggtct ggcgtatttc attatcttaa ttgtcacacg
    23941 caacttcttg aagcctctga acaatcttca tgatgtgatg cggacaattt ccaaaaatcc
    24001 agataatctg atgctgcgct cgggtatttc ctcgggtgat gaaattgagg aattgtccgt
    24061 tatttttgat aaaatgcttg ataagattga gacgcataca cgattgcaat caagatttat
    24121 tagtgacgtc agtcatgagc tgcgcacgcc agttgccatt atcaaggggc atattggatt
    24181 attgcagcgc tggggcaagg acgatagtgc tattttagat gaaagcctca ctgcagctgc
    24241 gcaagaggtt gaccgaatgg ctattatgat caatgacatg cttgatatga tccgagtaca
    24301 ggggtccttt gaagggcatc aaaatgatac aactgtttta gagagctcta ttgagaccgt
    24361 tgttggtaat tttagggtcc tgcgtgagga ttttgatttt acctggtact ctgaaaatca
    24421 aagaacccta gccaagattt ataaaaatca ttttgagcag gctctgatga ttttgataga
    24481 taatgcggtc aagtattcta ggaaggaaaa gaaaatcgtc atagaattag cggttaatgc
    24541 tagcaatgaa gctgtggtta aggtcaaaga cagaggtgag gggatctcag aagaggatat
    24601 taagcatatt tttgagcgct tctaccgcac cgataggtcc agaaatcgaa ccagcaccca
    24661 agcaggtctt gggattggct tatccatttt aaagcaaatt gttgatggct atcatttaca
    24721 tatggaggtt gagagtgagc taaataaagg gtcggtcttt attttgcgga ttcccttagc
    24781 tgatcatcaa ggctcatagc tgtatacctg cctgagtatc tagtagatgc tcaggctttt
    24841 gactgttcta atgtgtggtg tgatgatgag gtgtttatca gggaaggagg gctcttggag
    24901 gtaaacctga gtgcttgtct attcttttgt tatccctaaa attatggtaa aatagggtat
    24961 tagattaacg atagaattgg ggtgtttgcg tgcgttgtcc gaaatgtaac tataataagt
    25021 caagtgttgt tgatagtaga caggcagaag atggcaatac gattcgtcgc cgcagagaat
    25081 gcgaaagctg tcacacgcgc tttacaacct ttgagcgctt agaagagctt ccattactag
    25141 tgatcaaaaa ggacgggact agggagcagt tttcaagaga taaaatctta aatggtgttg
    25201 ttcaaagtgc ccaaaagcgt ccggtgtcaa gtactgacat tgaaaatctc atttctcgca
    25261 ttgagcagaa ggttcgtaca gcctatgaaa atgaggtgtc aagtactgtt attggcaatc
    25321 tggtgatgga ggaattagca gagcttgatg agattaccta tgttcgtttt gctagtgtct
    25381 ataaaagctt taaggattta gacgaaatcg aagagctctt acagcagatt actaatcgcg
    25441 ttagaggaaa aaagaagagc agtgtagatg atgaagccta ttgatacctt ttcttatatt
    25501 aagcataatc aggttcaata cgattcaagc agcctgattc agttgtattt tcctattatt
    25561 ggaaatgacg cagtggcagt ttatcagtat ttggttcact tttttgatga tggctcagga
    25621 gcccacaaat ttagtgatat tttaaaccat ctgcagtttg gaatgaagcg cctagaggaa
    25681 gccttggtga tgctgacagc tattgatttg ctggtcttat atcagctgcc agatgcttat
    25741 ttgataaaac tacatcagcc cttgggcagg gaagcctttt taaataaccc aatttatcgt
    25801 aggcttttag agcaaaagat tggagatgta gcggttttgg agttgcaaat ggtgattccg
    25861 aaccaggcta gaaacatctc aaagaccttt tcagatgttt ttggaataga ctctcaggag
    25921 cttaagcagc ctcagccatc aaagataaat tttgatttag atagctttca gcagctaatg
    25981 cggcgtgacg gtcttaggtt tgaggatcat caaaaggacg ttatcagtct ttacagtatt
    26041 tctgagcaat accacctaac ctggtttgac acctatcagc tggctaaggc aacagcagtc
    26101 ggcggcagca ttcgcccaga gcgcatgcta gtcaagaagc agcaagaggg cgctcaaaaa
    26161 acaagtgaat cgttctcacc agctgagcag gttgttctta gagagtctaa gcaggacacg
    26221 cctcttgtct ttttagagaa gatcaaaaaa gctaggcgag ctagagtcac aaaggacgaa
    26281 aaggaattgt tgctgactct agcccgcatg aatttcttgg acgaggtcat caatattatg
    26341 gtattatata ccttcaataa gaccaagtca gctaatcttc acaagactta tctgatgaaa
    26401 atggcaaatg attttgctta ccagcgggtt ttaacagcgg aaactgctat tatcaagaca
    26461 cgcgcctttg gtgagcgtaa gcagcaggca aagtcacagc agtccaatgt gcctaagtgg
    26521 agcaatccgg attatcaaga aaaaacaagt caggaagaac aggcaaagct agagcagttt
    26581 aagcaggctg ccttaaaaag gctggagaac ctaggaaaga gtggtgacta gatggaaaag
    26641 atcgggaaaa tggtagagca tttgggacag gctagtcgtg tagctagtgc tgagctgatt
    26701 gaggctatac ttgctgatca ggaggtggct gagtttatca aggctcacca gctatctcag
    26761 gcagaaataa agctgagttt atcaaagttc aaccagtttt tagttgagcg ccggaaatac
    26821 cagacaggtg atgagaccta tattgctaag ggctatcagc ccattttggt catgaacgag
    26881 ggctatgcag atgtgtctta cctagagaca agagagcttg ttgaagccca aaggcaggca
    26941 gctattgcag atcggattca tttggttagt ctgccaagat cttatcgtag ggtttctttg
    27001 tcagctgttg atgttaacaa tgccagtcgt atgcaggtgt tttcagagct tttggatttt
    27061 gttgagcagt atccagcggc agagcaaaag ggtctctacc tttatggcga tatgggggtc
    27121 gggaaatcct atctgatggc tgctatggca catgaattgt ctgaaaaaaa gggtgtatca
    27181 acaactcttc ttcattttcc tagctttacg attgatgtta aaaatgccat ttcaaatggc
    27241 tctgtcaaag aagagattga tgccatcaag catgtccctg ttttaatttt agatgatatt
    27301 ggtgcagagc aggcgacctc atgggtgcgt gatgaggtgc tacaggttat tttgcagcat
    27361 cgtatgctag aggatttgcc aacctttttc acctctaatt acagctttgc agatttggag
    27421 agaaaatggg caaagatcaa aggaaatgat gagacctggc aggccaagcg tgttatggag
    27481 cgtgtgcgtt atttagcacg tgaatgccat ttagaagggg ttaatcgccg ccagggctag
    27541 ctaaacgcta gctcaagcga tggataatga gataaagaaa aggagaatca tggttttacc
    27601 tacagttgcc attgttggac gtcctaatgt tggaaagtcc acgttattta accgaattgc
    27661 aggagagcgt atttctatag ttgaagacgt cgaaggggtt actcgcgacc gcatttacac
    27721 gactggtgag tggcttaacc gccaattttc attgattgac acaggtggta ttgatgacgt
    27781 tgatgctccc tttatggagc aaatcaagca tcaggctcat attgcgatgg acgaggcaga
    27841 tgttattgtc tttgtggttt ctggtaaaga gggcgttact gatgcagacg aatatgtctc
    27901 taagctcttg tatcgtacca acaagccagt gattttggtt gtcaacaagg tggacaatcc
    27961 agagatgcga aacgatattt atgattttta ttctcttggc ttaggagatt ccttcccggt
    28021 atcatcagtt catggtattg gtacgggtga tgttttagat gctatcattg ataacctgcc
    28081 gatagaagag ccagtagaaa acgacgatgt gattcgcttt agcctaattg gacgtccaaa
    28141 tgttggaaaa tcaagcctca ttaatgcgat cctaggagaa gagcgtgtca ttgccagtcc
    28201 tgttgctggt acgactcgtg atgcgattga tacaagcttt accgatgaat ccggtcaagc
    28261 ctataccatg attgataccg caggaatgcg taagtccggc aaggtctatg aaaatactga
    28321 aaaatactca gtgatgcgtg ccatgcgtgc cattgaccga tcagatattg tgttaatggt
    28381 tattaatgcc gaggagggca ttcgtgacta tgataagcgg attgcaggct ttgcgcatga
    28441 ggcaggtaag ggcatgatta tcgttgttaa taagtgggac accatcgaaa aggataatca
    28501 tacagtagct aggtgggagg ctgatattcg tgatcaattt caatttttga cctacgcccc
    28561 tattatcttt gtttctgccg ttacaaagca gcgcttaaac aggcttcctg agttgattaa
    28621 gcgtatcagt gatagtcaaa gccagcggat ctcgtcagct attttaaacg atgtgattat
    28681 ggatgctatt gcgatcaacc caaccccaac ggataaggga cggcgtctaa agattttcta
    28741 tgctacacag gtttctgtga agccgccaac ctttgttgtt tttgtgaatg aagaagagct
    28801 gatgcacttc tcttatctgc gctttctaga aaaccagatt cgtgctgctt tcacctttga
    28861 agggacacca atcaagctga ttgcgcgcaa tcgcaaataa gcccttttat tactcttgtt
    28921 agtattggaa gcagcgagtg ctgttgatgt gcggtgtcta gaccttgtgt gtcaggactt
    28981 ttgaccgacc aataagcctt accagaaatg agaggctgct atccaaatag agcttaccag
    29041 caagcaaggc gtgccaagca ttgatgtcac atgataatca ttagccctag gctagtgatt
    29101 ttttagtgct ttaaagccta tcagaacagc tatatacagc tactcaaata tgttttaata
    29161 gcctttaaga gagatttttg caggaaatct aagctgaagt ttgttataat caaaggataa
    29221 gcaaaaaggt gggagcagat atggctagat taattccggg gcggattcgc aatcaaggca
    29281 tcgagcttta tgagcaaggc ttggtgaaaa tcatagatga caggactgac cttcttcgag
    29341 cagaggtgga tacttatcag gttcaatatg gtatcaatga tgaggatatt aggtgtcagt
    29401 gtgattattt tgagcgaaag cagtattgcc agcacattgc ggctctagaa tattttctga
    29461 aaaataatca gaagggcaag tcgctctcag agcagcttaa caaccagctg gaaagtaagg
    29521 aggaaactaa aaagctgacc tcctttggta gtcttttttt ggacagtttg cacatgaacg
    29581 aggacgacac gaccaaatat aggcttttag cttctggtgc taaaagtcct ttctcatctg
    29641 attactggtg gagccttaag ataaatcgct tgcccggaga gaaggcttat gttatccgcg
    29701 atatcaaggc ctttattcat ttggtcaaag ttgagggctt ttaccagatt ggaaagaatt
    29761 actttgagtc tctttccata ttgcagtttg atcaggctag tcaggagctg attcgttttc
    29821 tttggcgttt atcaacgcat tcagataagt tagattacga atggctattt cctaaccacg
    29881 ctcgtcatct tcggttaccg gcaggctttt ttgaggaggg cattgacctg ctgacggggc
    29941 tttacgagtt ttcatttgag acctcctctc aaacctattc tcatctttat gttcgacctc
    30001 tggaggcaga ggctggtctc tttcagttta cagttgatgt tcatcgcagc tctattgagc
    30061 tttacattaa ggaaaaaaat atagagtatt ttttcaataa tgaatacctg ctatacatga
    30121 acacctttta ccacctgagc ctgaagcagc aaaaaatggt tcaagctatt cgcagcctgc
    30181 ctattgaggc cgatttggcc aagcacattc attttgatct tgatgatcag gctaagctgg
    30241 cagctagctt gctggaattt cgagagcttg gtcaggtgaa ggctcctaaa agctttgata
    30301 ttagagattt ccaagtgact tttgtctttg atattactga aaaaggtgag ttgacctctc
    30361 agctgatttt tgactatggg agcattcaga tcagtgataa ggcaagctta gaccagctcc
    30421 cctttgctag ccattataaa aaagaaagca gtatttatcg tgccttgaag cgctttgggc
    30481 tttctccgca gttttttgct aagaaagcct tgactgaccc caaggactgg tatcgctttt
    30541 ttacagaagc tgttccttat tttgaaagtc taggtagggt tcagctttcc tctaagctcc
    30601 aagatcagcg cttaatggaa agccctcagc ttacagtcaa acgtgaggga ggtcttttag
    30661 atatttcctt tgatttttca acggtttgtc agactgatat tgaaaaggct ttggccactt
    30721 tgtttagtga tcgctcttat tttgtcaatc agtcaggcaa gctggtcgtt tttgatgaag
    30781 agacacaaaa aatcagccgt agcttacagg aactaagagc taagcagctg gcaaatggtc
    30841 acctccagct agaaggaata gctgccaccc agctgtctca tctattttcg gatctgtctt
    30901 ctgttcattt ttctgaggag ctagagaccc taatcaagga cctgcagcac ccggatcgct
    30961 ttgagctggg agagctggcc gttaaggcca aggtgagaga ttatcagctg cagggcatca
    31021 aatggctctc tgtgcttgat aagtatggct ttggtggtat cttggcagat gatatgggct
    31081 tgggcaagac actgcaaatc attgcctttt tatcaagcag gctaaccgag acctccaagg
    31141 tgcttatctt ggcaccctct agcttgattt acaattggtt agatgagttt agtaaatttg
    31201 cccctcagat agatgctgct gtatcctacg ggctaaagcc ggcacgagat gctcttattc
    31261 aagaaggaca tcaggtgacg attaccagct attcttcctt taggcaagat ttagaaacct
    31321 atcaggcaaa tgattatgat tatttaatct tagatgaggc gcagatgatt aaaaatgccc
    31381 agaccaagat tgctcagagc ctgcgtgcct ttgacgtgaa gaattgcttt gctttatctg
    31441 gtacgccgat tgaaaataag ctgcttgaaa tctggtccat ttttcaaatt gttctgccag
    31501 gcctgctgcc atctaaaaaa gcctttttga aaatggaggc cagagacgtt tctcgctata
    31561 ttaagccctt tgtcatgcga cgcaaaaaag aggaggtctt gccagagcta ccagaattaa
    31621 tcgagatgaa ttattacaat gagatgtccg atggtcaaaa agcgatttat ctggcacagc
    31681 taaggcagat gcaggagcgg ctgtctgctg caactgatga tgatattaat cgcagtaagc
    31741 tggaaatcct gtctggtatc acacgtctaa ggcaaatctg tgatactcct agcctgttta
    31801 tggattatca aggaggaagc ggtaagctag acaatctaag aaccttgctg ctgcaaatta
    31861 aagaaaacgg tcatagggct ttgctgtttt cacaatttaa gggcatgctg gctcttgtca
    31921 agcaggaaat ggatcagctt ggcttatcat cttataccat aacaggctca acaccggcca
    31981 atgaccgtca agaaatgaca cgtgccttca ataatggctc aaaggacgcc tttttgattt
    32041 ccttaaaggc cggtggtgtt ggactcaatt taacaggtgc tgatactgtt attttgattg
    32101 atctatggtg gaacccagct gtagaaatgc aggccattag tcgtgctcat cgtattggtc
    32161 aggaggacaa tgtagaggtt taccggttga ttacccgcgg aacaattgag gaaaaaatac
    32221 tggagcttca ggaaaataag cgtcatctga ttaccactgt tttagatggc aaacaaggcc
    32281 tagcaagcat gtctgtcgag gagatcaaag aaatccttgg tcttcagccc tagcatgtat
    32341 ggcttttagc acacgctctt aagcctatca gctaaaggct agtgtctgtt ctctataaca
    32401 aataaggcaa gagaatagag gtgatgagct agtcacatca tttttgcttt gctgcctttc
    32461 tttttaggaa ttactttgaa aaataggatt atttagttta taatagggaa tgctatagga
    32521 aggagagtga gatagaatga caaagcatgc gtttcctctg gttgcagatg gtgagcctat
    32581 tattgagtca gctaggcaga tggctttata tgaaaacgaa gatttgatca caaatattgc
    32641 tggcagctat caagataaac attacgacga catcataaga gaccatcaat ttgctgagaa
    32701 gactcctgtc gtctctaaag gatcccttca tcattctcca gttgtcgatg aagatcatag
    32761 ctacgctcaa aaggccagaa ggcaagcaaa gcaggatgtc aaagaaaaaa gacaggctta
    32821 tattgctaaa aatatggctt atagcccaaa gcaggcaagc aagaaaggtc aaagtggggc
    32881 cttctcttct aaaaaaccag cgacagaatt gagccgtttt acagagaaat taaaccaaga
    32941 gtcttatatt ttagctgagc ttcctcgtca atataaggag ccgcaaaata ccagccaagc
    33001 agctgtcaaa aaaaataatt atgacttttt gaagcgcagc caaatctaca atcatcaaga
    33061 agacagagat catcgtgaaa agaccattgc tcaagagcta aacctgagtc gctttgaaga
    33121 tattaagtaa gctttataca gccttatgtc tgtcaacatt aaaaggagtt aacatgtcaa
    33181 aaacctatca ttttatcgga attaaaggat ctggaatgag tgccttagcc ctgctgctcc
    33241 atcaaatggg gcataaggtt caaggcagtg atgtggagaa gtattatttc acacaaagag
    33301 gcctagagca agcaggcatt accattttgc cctttagcga agataatatt tctccggata
    33361 tggagctgat agcaggtaat gcttttcgtg aggacaacaa tagcgaggtt gcttatgcga
    33421 tgcgtcatca gctgcccttt aaacgctacc atgagttttt aggtgagttt atgaagcagt
    33481 ttactagtct tggtgtagcc ggtgctcatg ggaaaacctc taccacaggc ttgttgtcac
    33541 atgtgctcaa gcacatgacg gctacttctt atttgattgg tgatggtact gggcatgggg
    33601 ctgccgatgc tcgttatttt gtgtttgaat cagatgagta cgagcgtcac tttatgcctt
    33661 atcacccgga atattctatt atcactaata ttgattttga tcaccctgat tattttacag
    33721 gccttgatga tgtgttcaat gcctttaatg actatgctaa gcaggtgaaa aaggctcttt
    33781 ttgtttacgg tgaagatgag gaattaagaa agattagctc tcctgcaccg atttactatt
    33841 atggctttga ggacactgat gatttcgtag cctttgatat cacacgcacg acaaatggct
    33901 cagactttaa ggtaaagcac aagggtcatg ctattggtca gtttcatgtt ccagcctatg
    33961 ggcgtcacaa tattttaaat gctactgcgg tgattgctaa tttatttatt gcaggctttg
    34021 atatgaagct tgttgcagag catctgaaga gcttttcagg ggtgaagcgt cgttttactg
    34081 aaaaggtgat caatgacact attattattg atgactttgc tcatcaccca acagaaatca
    34141 ttgcaacgct tgatgctgct aggcaaaaat accctaataa ggaaatcatc gctatttttc
    34201 agccacacac ctttacaagg accattgctt tgctagatga ctttgcccat gccctaaatg
    34261 aggctgacag tgtttatcta gcgcctatct acggctcagc gcgtgaggtt gataagggtg
    34321 atgtcaaggt ggaggatcta gcggctaggg ttgagcgccc agccaaggtc atctcagttg
    34381 acaatgtatc gccgctgctg gatcatgata atgcagtcta tgtttttatg ggagcaggtg
    34441 atattcagtt gtatgaacgc tcgtttgaag agctgctggc taacttaact aaaaataatc
    34501 aatgattaag cgacctgcct taggcaggtt ttctcgtcgt aaaggaggac ctatgctaat
    34561 tagacatgtg aatcagactg actgggagat tattgctgat atcgaacagg ccaatttttc
    34621 tccccaagag gctgtagcag ccaatgtgat aaaagagcgt gcagagctta tttcggatac
    34681 ctttcttgtg gctgttatcg ccaatcagtt tgtcggctat atcgaaggac ctgtcattgc
    34741 tgagccaagg cttgaggatc acctatttca tggtgtgacc aagaatccag caagaggtgg
    34801 ctatatagcc attaccagtc tttctgttgc tcctggatac caaaagcagg ggattggcac
    34861 agctctctta gctgcaatga aggatttagc agttgcacag gatcggctgg gtatcatact
    34921 tacctgtcat gactatttga ttccttacta tgagatgaat ggttttcaag atcaaggcct
    34981 gtcagcttca aagcatggtg gctctgtttg gtatcaaatg ctatggcagc cataggaagg
    35041 ctattaaagc ttagcatgta ttaagaatta gtaacaaaag ggggatttta ttgcatttat
    35101 agtgcaatta ggatataatg gcggttgatt aagtttagga ggaatggctt tgactgattt
    35161 taaagatgat gagcaaagac gtcagcagca aaaaagcttc aaagaaaaga ttctagccga
    35221 attagaaaaa gcaaatcaga ttagaaaaga aaaagaagaa gagcttttta aaaaggatct
    35281 agaggttcaa gaggctgcta gaagaacagc tcagctttat gcagaatata aaagacaaga
    35341 agcactaagc aataacccca aacaagcgtc tgatatagca gctgcgtcgc aagagacgac
    35401 ctcaacggct tcaacagccc acacctctgc gattaagcta gaagagacag cagtagctac
    35461 tggggatcaa gcattgtcgc caccagagga gcctgcattg agtgaaagcc tgcttaagga
    35521 agaggcaagt gtcgaaggtc agactaagaa gggtggtcca gtgagaagaa aaacaagtaa
    35581 gcgccagcag acagatcgaa tggccaaaaa aatttcgaca gtactgatat cgtcgattgt
    35641 cgctattatt gtggtgattg gcctcgcagg gacagcctat gtgtatagtg cccttaaccc
    35701 tgttgacaaa aatagcgatg actttgttca ggttgaaatc ccagccggct caggcaataa
    35761 gcttattggg cagatccttg aaaaagaggg gctgatcaaa aatagtaccg tctttagctt
    35821 ttacactaag tttaaaaatt tcactaattt tcaaagtggc tactacaacc tacaaaagag
    35881 catgagccta gaagacattg cccaggcctt acaagagggt ggcacagcag agcctacaaa
    35941 gccagtacta ggaaaaattt taattccaga gggctatacc attaagcaaa ttgctaaggc
    36001 catagaaact aatagtaggg caaagaatcg tagcaaggct aaaacaccat ttcactcaaa
    36061 ggatttcttg aatttggtga caagtgatgc ctttattcaa gagatggcta aaaaatatcc
    36121 gaaattgcta ggagatcttc caagcaagga agtagctact tatcagctag aaggctacct
    36181 tttccctgcg acctataatt attataagga aacaacacta aaagaccttg cagaggaaat
    36241 gattgcagcg gcaaatgcaa acctagcgcc ttattatgag gcgattgcag ctagtggcaa
    36301 gacagttaat gaggtgctga ctttggcctc cttagttgaa aaggaaggct ctactgatga
    36361 cgatcggcgt caaattgcca gcgtatttta caatcgctta aataatggca tggccttaca
    36421 gtctaacatt gctatattgt atgcaatggg taaattggga gaaaagacaa ccttagcaga
    36481 ggacgctgct attgacacaa ccattaattc tccttataat gtttatatca atactggctt
    36541 aatgcctggt ccagttgata gtccagggct tgcagctatt gaggcgacta tcaatccagc
    36601 ggcaacagat tacgtttatt ttgtagccga tgtgcgtact ggtgaggttt attatgcaaa
    36661 aacatttgaa gagcactctg caaatgttga aaaatatgtt aacagtcaaa ttcagtaagg
    36721 acaaacatgg tgctttagca tcatgtttgt gtttctgatt cgtcaaaaga aaaaggaaaa
    36781 gagaaagata atggcagaaa agacttatcc aatgacagca gcagaaaaag aacagcttga
    36841 aaaggaatta gaagagctaa aattagttcg tcgtccagag gttgttgagc gcataaaaat
    36901 cgctcgttcg tatggagacc tttctgaaaa ctctgaatac gatgctgcta aagatgagca
    36961 ggcttttgtt gagggacaaa tctcaacctt ggagacaaag attcgctatg ctgagattat
    37021 tgatagcgat gctgttgcca aggacgaggt ggcgattggt aagacagttg ttgtccagga
    37081 ggttggcaca caaacaacag acacttatca tattgtcggt gcggcaggag cagatatttt
    37141 ttctggaaag atttcaaacg agagtccaat tgcacaggcc ttgattggta agaaaacagg
    37201 agataaggtt aagattgagt ctccagcagc tacctatgag gttactatca tcagcgttga
    37261 caaaacacaa taagacttat ctgactatca gtgcagtgtc ctgatagtct ttttagtggc
    37321 ttgcttttta atatcagttg ttgtggtcta ttaaaaagag ctgcacttta gaaagtttta
    37381 actaagatac tttatgacct agtctcatac attaaaaaag cgaacaggtc taattttcgg
    37441 aatccctgaa aattagacct gttcgtttgt tttatcttga gtcagacttt tgtcacagac
    37501 tcttttagct atcttagcga cgcttttttt gtttaccggc gtttcggttt aacttagtcc
    37561 tcttgcttgt gctaagggct tgcttttcag ctgtaacgtc cttgcgtggc tggtgagatt
    37621 tataggcctt aggagggttc tttgcgaact cctctgcaat ttgcttgcgg agccttggtt
    37681 ttaaaaggta ggttgtgatc aattgctgaa tgatactaaa gaaaccacca actagccaat
    37741 acaagcctaa tccggcaggc aggtaaaacg acatgacaat catcataatt ggcatggtgt
    37801 acagcatggc tttcatttgt tcacgttgct cctcagggac tgccatcatt gacagccagg
    37861 attgaacgaa gtataaagcc gcaattacag ctgtaagcaa gacgctgcga tgccccaggt
    37921 caatgcccat aaaggtactt gttgagactc ccttggtaaa ttggaccgca acatacatgg
    37981 cagaaaagaa aggcatttga atcagcagtg gcaaacagcc tataccgcct agcgggttga
    38041 ctccattttc acgctgggcc gccattaatt ctgtttgggc tgccattttt tcttcagtgc
    38101 ttgtagcgtt tttgatgcgt tgattaattg gctcaaaaaa aggctttagg taggccattt
    38161 tttctgattg gtagcttgcc ttccatgatt ggtagagccc aagtggtagg ataatcgttc
    38221 taacaataat agttacaaca atgatggcaa gaccatagcc tagggcggtg ctgttagcaa
    38281 agtaatcaat gagaaaggaa acgggctttc caaggtaatc ccaaatgatg ccctccgggt
    38341 gccccttggc gtctctgccg acacaccctg tcaatgtcag taggaccgat aaggcaagtc
    38401 ctgagaaaag tatgcgattc gttttgagtt tcaatgtgtt tgtcctttaa tttttaatat
    38461 acctaaccat tttactgttt ttttgagaaa ttaacaatag ttctacagta ggatttttaa
    38521 ttgctgatcc taaaatcatg gaaatcctca aagtgagatg gattaacatc aacataggtc
    38581 acctttgccc atttagaagg tccttttctg atttcctgga taaagcgcgt catctttgca
    38641 gggtcactag cctgtgctaa aatctcaaca gtcccatcac tattgttcca cacgcggccg
    38701 taaatatcac caatttccaa agctagtgcg taggttgaat agcgaaagcc aacaccctgc
    38761 accctgcctg aaacgattag tctgaccttt ttcataagtc acctcttttc tttttattat
    38821 agcatagata gcttataaat actaaaagtt gtcatggagc aggcagccaa aggataggca
    38881 aagactgcaa gtgggctatc tgctgaggta aacaataggt cttagtgcag caaggctatg
    38941 tttatggtta gctctccttc ttgtcttcta aaaaggaaag ctaatgggct tacgacacct
    39001 gataagggga gaaagctcct tttaggctga tagccttctg atggttttta tgcaaaagag
    39061 tgaacaattt tgtgatataa taagaccatg attatcacat caaaagcaaa ccatttgatt
    39121 aagcaggcta agaaattact gcaaaaaaag catcgcaagc actcttactt gattgagggc
    39181 tggcacctat ttgaggaggc tcagagatct gggcaggaat tgatacatat ttttgttctg
    39241 gaggaaatgg cagagcgctt atcaggcttt gatcaggttg tcatcgtcag tccagagatt
    39301 ctaaaggagc tgacgagctc tcccaatcca cagggcatta ttgctgaggt taagctttgt
    39361 caacaggcct taccgactag ctatgctgga aaatatttga ttttagagga cattcaggat
    39421 ccaggcaatc tagggacaat cattagaaca gcggacgcag caaagtttga tggggtgttt
    39481 ttgtctgaga agtctgcgga tgtctacaat caaaaaactc tacgctccat gcagggcagt
    39541 cattttcacc tgccgatttg gcgaacggat atttatcagg tcagtcaggt gatgcagcag
    39601 caaaaaatac cagtgctagc aacgaccttg tctcaggatt cgattgatta caaggacctc
    39661 tcagctagga gcagccttgc ccttgtttta ggaaatgaag gtcagggcat tagtcctgag
    39721 atggcagctt tggctgatca gctgattcat attagcatgc ctggacaagc tgaaagctta
    39781 aatgttgcag ttgcagcagg aatcctcatt ttcagcctaa tttaagctag tatggtataa
    39841 taatgatgtg aggtgattag tgtatgcatt atacagaaga tacagaatac atggagcatg
    39901 ttggtcattt gattgctcac cctcgctttc aaaggcttgg agatattgtt cagcatcacc
    39961 attctactcg cttagagcac tctgtcaatg tttcttattc tagctatagg ctggcaaaga
    40021 ggcttggctt agacgccaag agtaccgcac gaggtggctt gctacacgat ttcttttatt
    40081 atgattggcg agtaaccaag tttaacaagg gacacgcttg ggtgcaccct agaattgctg
    40141 ttcgaaatgc taaaaaatta acagcactca acaaaaaaga agaggatatt atcctaaagc
    40201 atatgtgggg agctactatt gcttttcctc gctataagga aagctatatt gttacctttg
    40261 ttgataaata ttgggcggtc aaggaggcca tgacgccgct gcgtcaaaaa tggacgaacc
    40321 gtcgcttcct gcgtcgaaag acgcttcaaa gtcacaatca ttaagtaaaa aaaggagtta
    40381 tgatgaacga taatgttatt tacacacagt ctgacgcagg cttgagccat ttttttgcca
    40441 aggtctatag cctggttggt atgggagttg ggctttctgc ctttgtttct tatttgatgc
    40501 tgtttccatt taggcaaaat ttagtctcga ttgttcttga tcatcctatg gtctattatg
    40561 gggcggctat tgttgagctt gtactggttt ttgttgctag tggtgctgca cgtcgcaata
    40621 caccagcagc tttaccctta tttcttgtct attcagcctt aaatggcttt accttgagct
    40681 tcattattgc agcttatgcg caaacaacgg tgctacaggc ctttatctca tcggcagctg
    40741 ttttctttgc tatgtcactg cttggtgtta aggttaagcg tgatctgtca ggtattcgaa
    40801 aggccatgtt tgcagccttg attgggatta tcgtggctag tctggtaaat ctctttatcg
    40861 gtagtgacct gatgagctat gtgatcagcc ttatttcagt gttgatcttt tctggcttga
    40921 ttgcttcaga caatcagatg atcaagcagg tctaccaagc ctctaacggt caggttggtg
    40981 acggctgggc tgtcgctatg gctcttagct tatacctaga ctttatcaac ctctttatca
    41041 gtctacttcg tctcttggga agaaatgact aatagctatt ttaagcgcag ctgctgattg
    41101 tcacttaatc gctattacga gaaatcagcg aagctgcagg tgttaccttt tgttagaaaa
    41161 gagtggctgc tgctagtaag aaagtagctg ctaggagagc ctgatgagcg tgactgtcaa
    41221 ggaaggccag ttactattgc taccatctag ggaaggtacc aaaaaaagtc aagaagcggg
    41281 cccaagggct cgtttttgtt tgcttgattt gtggtaaagt gcttcaaacc aagcctatat
    41341 ctagtctgat agctcttatc agctgacaac atcatattta caatgcctgt tggtgtagat
    41401 ttgtaaagca tgctcttttt tggtataatg agaggaacaa aaaatcgagg agaatatcta
    41461 tcaatatgtc tacagctatc tggatattat taatcattgt tgctcttaca gccggtcttt
    41521 ttggtgggat ttttattgcc cgcaagcaaa ttgaaaagga aattggagag cacccacgat
    41581 taacgcctga ggccattcgt gaaatgatga gtcaaatggg tcaaaaacca agtgaagcga
    41641 aaattcaaca aacttaccgc aacattgtca agcaatcaaa agccgcaatg actaagggta
    41701 aaaaataggt tacggattag aaatcgtggt ttctaagcaa tagctaagag tgaacagtct
    41761 ttgatgttaa aagcttgttt agagcttgca ttgtcagtta gaggtgtcaa ctgttcaggg
    41821 gttaacaata gactcagttg gctcttacca gctgagtttt ttatgcttca atgaggaaat
    41881 aatcgttatg gacaatagac caattggttt tttagattct ggtgtaggag gcttaactgt
    41941 tgttagtgag ctgatgcgtc agcttcccca tgaaaaaatc atttatattg gtgattcagc
    42001 aagagctcct tatggtccta gacctgctga acaaatcaga gaatatacct gggagttggt
    42061 tcgtttttta ttaacgaaac atgtcaagat gattgtcttt gcttgtaaca ctgcaacagc
    42121 tgttgcttgg gaggaggtca aggaggcttt ggatattcct gttttgggcg ttatcctgcc
    42181 gggcgctagc gcagctatca aggctactag tggaggaaag gttggtgtta ttggcacatc
    42241 aatgactatt tcttcaggca tttaccagga aaagatccag ttgctggctc ccactgttca
    42301 ggtaactagc ctagcctgtc ctagatttgt tcctattgtg gagtccaatg agataagctc
    42361 aagtgtggcc aagaaaattg tctatgaaac cttggctccc ttagttggaa agatagatac
    42421 ccttgttttg ggctgcaccc attatcctct tcttaggacg attatccaaa atgtgctggg
    42481 accacaggtt aaattgattg atagtggggc agagtgtgtg cgtgatattt ctgttctttt
    42541 aaattatttt gagattaatg gcagtcgaga tgatgaacat aggcgtcatc atttttacac
    42601 tacagccggc tcagacagct ttcaagcaat tgcctcagcc tggctaaatc aaacgataga
    42661 tgtggagcat gtgaccttat gagtgataac atttatgaat acaaggataa agacaattgg
    42721 tttattggca agatgacagg ccataattta atggctggct ggggggttaa ccatgagctt
    42781 attgccaaaa tagacgatat gttaggtgcg attgctggtg atgtggattg ggaaagtccg
    42841 gtcggttatg atgtgactgt tattcgttac gcctcccctt ttgccttgat tagctttgtt
    42901 gttggcatga tcaatcagaa agccaatcga gcccttaagg ttgttcggca ctcaggtgcg
    42961 attttagtga ccgaaaacga gcgattgctt gctgtgcata tgccagatga tggcgtccct
    43021 gtggctgact tctttggtca acaggcagat ggctttgggg atacgatttt gattgcgact
    43081 cgaaatgaag gcaagaccaa ggaatttcgc cggctttttg gtgatatggg atatcgcgtt
    43141 gaaaatctca atgattaccc agagcttcca gatgtggcag aaaccggggt cacctttgag
    43201 gaaaatgccc gcctaaaagc agaaaccatt tcaaggctta ctggaaagat ggttctggca
    43261 gatgattcag ggctcaaggt ggatatttta ggtggcttac ctggggtctg gtcagctcgt
    43321 ttttcgggcc ctgatgctac tgatgagact aataatgcta agctattgca tgagctggca
    43381 atggtatttg atcaaaagga tcgctctgct caatttcata cgaccttggt ggttgctgca
    43441 cctggtaaag acagcttggt tgtcgaggct gattggcatg gctatattgc aaccaagcca
    43501 aaaggcgagc atggctttgg ctatgatccc ttgtttatcg ttggggagac tggacgtcat
    43561 gcagcagagc tagctgctga tgaaaaaaac aagctgtctc ataggggaca ggcggtcaag
    43621 aggttaatgg aggtatttcc agcatggcaa gcaaaacaat cattgtgatg agcgattcgc
    43681 atggcgatcg tgaggttgtg gcagctatta aaggccgtta ccttggaaag gttgatgcca
    43741 ttttccataa tggcgattct gagctagaaa gctcagatcc tatttgggag gggattcatg
    43801 ttgtggcagg caactgtgac catgatagcg gctataagga tagcctagtc acctcctttg
    43861 atggcttgac tattgctcaa acacatgggc atttgtatca tattaacttt acttgggata
    43921 ggctagatta ttttgctcag gagactggag cggatatttg tttgtatggg cacttgcaca
    43981 gacctgctgc ttggcaattg ggcaagactg tctttatcaa tcctggctcg gtcgctcagc
    44041 cgcgtggtga ggtgaatgaa aagctgtacg cgcgtgttga atggacagca gcttgcatta
    44101 gggtggatta ctttacctgt cagcataagt cttacccatc actttctaag gaatttaaac
    44161 gatgatagca aaagaatttg aagccttttt aatcagtcat ttggatagct acctgattcc
    44221 agcagaggag ctagccattt ttatcaacac gcataatgct gatcatgtca tgctcttatt
    44281 ggttagcaat ggtttttcac gagttcctgt cattaccaag gaaaagcaat atgtcggaac
    44341 gatcagcatt tctgatataa tgacctatca agccaaaagg cagctaacag actgggagat
    44401 gacgcaaact aatattggcg acatggtcaa tacaaagatt gagaccatca atattacctc
    44461 tagcttgact gaaatcatgc ataaattggt tgattttccc tttttaccag ttgttaatga
    44521 tgacaatcga tttatcggta ttattacgcg taagtccatt ttgaaggcgg ttaatagcct
    44581 tttgcatgac ttcactgatg aatacacaat cacaaaaaaa tgatagcatt tattgaaccc
    44641 tttctagcaa gcaaatctct tgctaataac agccagcaat cctatcgcta tgatttaagg
    44701 cagttttgcc agcaggtcgg acagcgtatt aatcctgaaa ccctagccct ctatcagcaa
    44761 agcttgtctg gccttacggt agcagctaaa aagcgcaagc tttcaacggt caatcagttt
    44821 ttgtactatt tgtaccagca gaaggctttg acagactatt ttaaaatgga cgataggata
    44881 gaagcctctt tttctttgaa gccccagctg acaaggcttg acaccagcgc tttttatgct
    44941 gaaacagcct tcctaaaagg gcagctcatt gcgctgctga ttctggagct gggcttgacg
    45001 ccaagtgaga tagcagggct tcgtcttgct gattttgacc tgggtcttca ggtgctaagg
    45061 ttgcaatctc acagaggcat tcgtgtgatg accttatcaa aggccttgct gccatttttg
    45121 gaaaaggcaa cagaagctca gcagctctac ctctttgatc atgacgccaa gcccttttca
    45181 aggcaatggt tttttaacca gctcagagat tttttagaga gcattggctg tgcggagctt
    45241 tcagcccaga gtctgagaga gcaattcatt ttaaatgaaa aagcagccgg taaatccatc
    45301 attgaggtgg ctcagctgct ggggctaaaa agcccgatca ccttagaaaa atattataag
    45361 atgtaatgga tataaaagta aaagattttg aaggtcctct tgatttactc ttgcacctag
    45421 tgtcaaagta tgaggttgat gtttaccagg tgcctattgt ggaggtcatt gaacaatact
    45481 tggcctatat tgagaccctg caggcgatgc gcttggagct tgctggagag tacatgctga
    45541 tggctagtca gctgatgctc atcaaaagca gacgactgct gccaaagctg gtagacaagg
    45601 agcctgatga ggaggatctt gagcaagagc ttttgggtaa gattgaagaa tatagtcgtt
    45661 tcaaggctct gagtcaggag ttggccagcc agcatgacaa gagggctctg cttttttcca
    45721 agccaaagca ggagcttatc tttgagcagg ccgtcctaca aaaggataaa acagtcatgg
    45781 atttgttttt agctttttca cagttaatgg ctgcaaagca agaggccttt aaatataacc
    45841 atacggttat tgagcgagat gattatcgta ttgaggatat gatggagctt attgaagcta
    45901 ggcttgagct agagcaggag cttactttga cggatttatt gaagcattgt gatcatctca
    45961 atgaggccat taccttgttt ttagcaagcc tagaattaat caaacggcag cttgttggta
    46021 ttgagcagac atcacatttt ggccagattg ttttgcgaaa ggagatccaa tgacctattt
    46081 atctcagctg gaggccttgc tgtttgtcgc aggagaagaa ggactaagcc tacgtcagtt
    46141 ggccagccta ttagagttaa caccgacagc cttacagcag cagctcgaca agctttctca
    46201 gaaatacaaa gaggataagg aatctggcct gtgcttgatt gagtcctcta ggacctataa
    46261 gttagtcacc aaagagtgtc tggctccctt gcttaaagac tatgctaagg ctccaatcaa
    46321 ccaaaccttg tcacgagcaa gcctggaggt tttgtcaatt gttgcctata agcagccgat
    46381 tactcggatt gaaattgacg agattcgtgg tgtcaattca agtggtgccc ttagtaaatt
    46441 agtggccttt ggtttggttc aagaggctgg caaaaaggaa gtgattggtc gaccaaatct
    46501 ttatgcaaca acagattact ttcttgatta tatgggtatc aatcatttag aagagctggt
    46561 tgatatttct tctattgctg ttgaagagca agagacaacc ctgttttaaa ggcaaagagg
    46621 agcttgtctc atttgcagat aggccttatg ccctctacta gaagagataa cagtcctaac
    46681 aaggtatagt gcctgaaaat cctattgtcg ttatggacag cggtcttttt aggcatgcta
    46741 ttaataagag tagacctgtt taagctagtg agcttttacc cataggagag tgactggtct
    46801 gttggagcta tcatcagatt tcctaataag aaagagagaa ggataatgag aattaacaaa
    46861 tacatcgccc atgcaggcct tgctagccgt cgtaaggctg aagagctgat caagcgaggg
    46921 ctggtgaccc taaatggtca ggtgataaca gatttagcaa ctactgttaa atcaggcgac
    46981 cttgttgagg tagaggggat tcctatttac aatgaagaga aggtttatta tctcctcaac
    47041 aagcctcgtg gtgtcatctc aagcgtttca gatgataagg ggcgtcagac agtgattgat
    47101 ttgctgccgc aggttaagga gcgcatttac cctgttggtc gcttggactg ggatacctct
    47161 ggcttattaa ttttgaccaa tgatggtgat tttacagata aaatgattca cccccgtaat
    47221 gaaatcgaca aggtttatct ggctcgtgtc aagggagtgg taactaaaga aagcctgcgt
    47281 cccttaacac gtggtgtcgt tattgatggt aaaaaaacaa agccggctcg ttaccgcatt
    47341 attcgtgttg agcctgataa aaatcgctct attgttgaac taaccattca tgagggccgt
    47401 catcatcagg tcaagaaaat gtttgaagtg gttggacact tggttgataa gctatcaagg
    47461 acacagtttg gcagccttga tgtcagaggc ctaaagcccg gagaagccag aaggctgagc
    47521 aaaaaagaag tcagccagct acatcattta gcgagcacac gaaaatgatc aaagccctac
    47581 tcattgctcc tgtcagagcc tatcagaaat atatttctcc cttatttcct ccttcctgtc
    47641 gttatcagcc gacctgctcg gcctatatga ttacagctat tgaaaagcat ggtgctaagg
    47701 gtgttttgat gggacttacc agactattaa ggtgccaccc ttttgccgct ggcggagaag
    47761 acccggttcc agataccttt tccttaaaaa gacatttcat aacgcatgaa aaaatacagg
    47821 attttgacca aaaaactgat tgacaatagc agttaaagtg ctataatagc agttaagtat
    47881 tcgttggttt aaatcaaacc tgttatgatt taagttagcg agtcaccgtc aaccacattg
    47941 tttgctgagc atgactccgg gcagtgtggt ttttttgatg aaaagagtaa gcgggacaag
    48001 catgaaacaa gaaatcatta atagacaata tagggaaaaa gatagtcaaa accatgtggt
    48061 gctctttcag ccacaaattc cacaaaacac aggaaatatt gctaggacct gtgctgccac
    48121 caacacgcct ttacatatca tcaggcctat gggctttccg attgatgacc gtaagatgaa
    48181 aagagcgggg ctagattatt gggataagct agacattaga ttttatgatc atctagatga
    48241 atttttagca caatgtgatg ggagcttgca tgtgattagc aaatttgctg atagggtata
    48301 ctcagatgaa gcctacaatg atcgtcagtc tcattatttt ttgtttgggc gtgaggatac
    48361 tggtctgcct gagcccttta tgcgtcaata tgctgatagg gcactcagga ttcctatgaa
    48421 tgatgagcat gtcagaagtc tcaatgtctc taatgctgtt tgcatgatcg tctatgaggc
    48481 acttagacag caagccttta agggcttaga gcttagccat acctatgagc atgacaaact
    48541 aaaatcataa taagcatatc gcaaaacatc agttagattg aagaagtatc cgtaggggag
    48601 cttcttcagt ctttttttat tgtattcttt gcttattaac caagcagttg acacgaaaat
    48661 tccaatagat cgtttaaagc caataaaacc attattaggc ttgcattaca ggcaggtatc
    48721 aaagaaagat atagaaaaat ataccagaaa aaaatctcat aaaagtgtca aaatagtaaa
    48781 aaatcgccaa aaatatgtca atattatacc attattatag tataatattt ataatcatat
    48841 tataatatta aaatatctgg tgtctagctg tttttgtaaa agcaaaaaac ctgcaccacc
    48901 ttatgataaa gcataaagga atataagcat gatagtctac ctaaagcaac acaaaaatta
    48961 ctggaaatta gtcagcatag cagctttaat cattatttta ggaggaatac taacaatgaa
    49021 ttggcttaat ggggataggg acaataaagg cgagaataac tactatcaag tagagaagga
    49081 tttagcaatg gaaattgtta gtgagtttga aggagtaaaa gagattagct ttcttagtcc
    49141 agtacaatcc aaagaaacag ggtattgggg aacaacagct actataaata aaactaatga
    49201 gatatcttat tctttttcga tgactttttc aggaaagctt gatgattatt cttactatta
    49261 cgataaatgt tttaaattag tgaagcgtca caaaaaattg acattaagtc aagtggatct
    49321 aacagatatt gatattaaat attctaaggg agggaaataa atgataactg acaaaaacta
    49381 taactggcta gctggaaaag tatatgatgt tgatgctaat aaagtaacta ttcctgttag
    49441 aaaaaatacg gatattctta atcgttatgt caaagtcctt gaagccgaag acaatcctga
    49501 caacggtatg cagtttacgg tgtcaaagag taataggaat gttctagctt taaattataa
    49561 actaaggagc ttctatgaca gtaaaaaaga aagtcatcat tttattagga atggtagcaa
    49621 ttttagtaat gggaggtata tttatgttta gctataatca gaatcaagcg aaaatgttag
    49681 aacgacaatt taaccatgaa caaaaacgaa ttgtcttgta tttgttaaat cattatagcg
    49741 gaattaatga gatagaattt aatgatattg aaaacaacag tacaacaggt tctaagaatg
    49801 tattgctgac aataaataat aaaattaaaa tggaagttac attttttaat ttaaatgatg
    49861 atacagataa ctatgttatt agttggaatg ggaaattaag tttgatagac aaaaatccta
    49921 taactcattt aagttcaata gataaaataa aagtaaaata ttggagtaac aatgatagta
    49981 acagataaaa attataatga tatagccgat ggggtttata aggttgatgc tggcaaagtt
    50041 attagacctt ggcgaaacgg taagactttt aaaactaacg ggaaagatta ccgcgtcctc
    50101 aaaacagaag acaaccccga caatggtatg caggctattg ctgtagctcc gattaagggt
    50161 agtgaggtgg gtaagagtca tatcatgatt gtttatgtaa aaagcagcta ttggctagcg
    50221 tcctagcaat aaaaggagtt gatgatgaaa aagcaacaaa gcaaacgacg gaaactaatt
    50281 ggcatagtgg ctttaataac aattttagga ggaatactaa caatgaattg gtttaatgac
    50341 gaaaaactaa atagagagcg tagagaacaa gagagggcag ctatttattt tagtaataca
    50401 tatgaaaata tacataaaat aaagatcatc ggtatagata aaaatttaaa aacaggttct
    50461 atgaataaag ctacaattgt taatagtaag tactatatat ccgtaacgtt tatgggaggt
    50521 gagatttata caggtgtaga gcaagcttca aaagacaatg aggaattttt aaatcgtcga
    50581 aaaaaagcag agaataagac aaccttgagt aaggacattg aagttattta taaggagaaa
    50641 tagtagtggt tagtgataaa gattataata aactctctga aaaagtatat gatgttgatg
    50701 ctaataaagt aactatttct gttagaaaaa atacggatat tcttaatcgt tatgtcaaaa
    50761 tcctcaaagc cgaagatacc cccgacaatg gtatgcaagc tatggctgtt gt
//
LOCUS       DARYNN010000010        49070 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.010, whole genome shotgun sequence.
ACCESSION   DARYNN010000010 DARYNN010000000
VERSION     DARYNN010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 49070)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49070)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49070
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.010"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(175..645)
                     /locus_tag="TVB59_000517"
                     /pseudo
     CDS             complement(175..645)
                     /locus_tag="TVB59_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            860..1081
                     /locus_tag="TVB59_000518"
     CDS             860..1081
                     /locus_tag="TVB59_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009568291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEL1009455.1"
                     /translation="MDTKFTALTEEQLKSVEGGKNGVVKLPGGTGVYCWNTGKNSAKC
                     GMDWSVAGPYVGKIIVNGWVNHGPWASRP"
     gene            1111..1404
                     /locus_tag="TVB59_000519"
     CDS             1111..1404
                     /locus_tag="TVB59_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL1009456.1"
                     /translation="MNERDLVQLIEQTLKDEEVQNNVTYRNLLEESLQQLSLKKPVYL
                     VSTRLAGHISTYLMTNHYEAPKAIIVLAQSIASTPAKHRGLISIPFWLSNIFR"
     gene            2541..4373
                     /gene="lepA"
                     /locus_tag="TVB59_000520"
     CDS             2541..4373
                     /gene="lepA"
                     /locus_tag="TVB59_000520"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEL1009457.1"
                     /translation="MNSQELKKRQENIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYKAKNGQDYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GLDASEAVLASAKSGIGIEDILEQIVEKVPAPSGDVDQPLQALIFDSVYDAYRGVILQ
                     VRVVNGMVKPGDTIQMMSNGKTFDVTEVGIFTPKAIGRDFLATGDVGYIAASIKTVAD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGIYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVNITDGDMLE
                     VSNPSEFPDPTKVDSIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYHIPLAEIVFDFFDKLKSSTRGYASFDYEIAEYRRSQLVKMDILLNGDKVDALSFI
                     VHRAFAYERGKLIVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDESKK"
     gene            4915..5352
                     /gene="msrB"
                     /locus_tag="TVB59_000521"
     CDS             4915..5352
                     /gene="msrB"
                     /locus_tag="TVB59_000521"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEL1009458.1"
                     /translation="MESKEELRQRIGDLAFEVTQHAATERAFTGQYDDFFEKGIYVDV
                     VSGEVLFSSLDKFNSGCGWPAFSKPIQHRMVTNHHDSSHGMRRVEVKSREAGSHLGHV
                     FNDGPKEAGGLRYCINSAALKFIPYDQMEQEGYAEWLGIFDKS"
     gene            5640..6659
                     /locus_tag="TVB59_000522"
     CDS             5640..6659
                     /locus_tag="TVB59_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEL1009459.1"
                     /translation="MLTSLEKLPGVLLCLLLALPAWYLGSLFPIIGAPVFAILLGMLL
                     ALVYQKRDYTKSGIALTSKYILQLAVVFLGFGLNVTQVLVVGLQSLPIIVVTIVTALG
                     ISYLFKRWLRLPAKTAILVGVGSSICGGSAIAATAPVIDAQDDDIAKAISVIFLFNIL
                     AALLFPALGQMLGLSNHGFAIFAGTAVNDTSSVTATATAWDAIHQSNTLDGATIVKLT
                     RTLAIIPITLGLSIYQTKSRQAHTTEGSFSLRKAFPTFIVFFLLASLITTFAASLGLP
                     MAIFHQLKLLSKFFIVMAMAAIGLNTNLVTLVKTGGKAILLGGICWLAITSVSLAMQA
                     ALGSW"
     gene            7003..7428
                     /locus_tag="TVB59_000523"
     CDS             7003..7428
                     /locus_tag="TVB59_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000823118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HEL1009460.1"
                     /translation="MKRKFLIGSHGRMASGLKSSIDILAGRGQELQVIDAYIDDSDYT
                     EQVLTFIEDVAADEQALIFTDLLGGSVNQKIVTALMDSGKENIFLISNSNLAALLSLM
                     FLKPEEELTKDEIVATINDSQVQLVDLAPATAAEDDFFN"
     gene            7443..7934
                     /locus_tag="TVB59_000524"
     CDS             7443..7934
                     /locus_tag="TVB59_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1009461.1"
                     /translation="MITQIRVDDRLIHGQVAVVWTKELNAPLLVVANDEAAKNEITQM
                     TLKMAVPNGMKLLIRSVEDSIKVFNDPRAVDKRIFVIVSSIKDACQIAKQVKDLEAVN
                     VANVGRFDKSDPATKVKLASSLLLNPAELEAAKELVSLPNLDVFNQVLPSNSKVSLSQ
                     LIK"
     gene            7952..8761
                     /locus_tag="TVB59_000525"
     CDS             7952..8761
                     /locus_tag="TVB59_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017644846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEL1009462.1"
                     /translation="MLVPATMAALAVLICFGGNYLTGQSMMERPLVVGLVTGLLLGDM
                     KVGILMGASLEALFLGNVNIGGVIAAEPVTATAMATTFTIISHIDQKAAMTLAVPIGM
                     LAAFVVMFLKNVFMNIFAPMVDKAAAANHQGKLVMLHYGTWIVYYLIIASISFIGILV
                     GSGPVNAFVEHIPQNLMNGLSAAGGLLPAVGFAMLMKLLWTNKLAVFFLLGFVLTAYL
                     KLPAVAVAALGAVICVISSQRDLELDAITKGAISNQSSFDSKESEEEDFFA"
     gene            8758..9585
                     /locus_tag="TVB59_000526"
     CDS             8758..9585
                     /locus_tag="TVB59_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEL1009463.1"
                     /translation="MRSQDNLTKEERKMLRSVFWRSWTMNASRTGATQYHAVGVIYTL
                     LPVINLFYKTDKDKADALVRHTTWFNATMHINNFIMGLVASMEKKNSEDPTFDASAIT
                     AVKASLMGPISGVGDSFFWGILRVIAAGIGISLASTGSAMGAVVFLLLYNIPAFIIHY
                     YSLYGGYSVGAGFIKKLYESGGIKIVTKTSSMLGSMMVGSMTASNVKFKTILTVAAKG
                     AKEAASIQNYLDQLFIGIVPLLVTMTAFWLLRKKVNINWIMFGIMLLGIVLGLLGIC"
     gene            9775..11409
                     /locus_tag="TVB59_000527"
     CDS             9775..11409
                     /locus_tag="TVB59_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL1009464.1"
                     /translation="MEERFKKRLQDDISHHFSHQSLILSILLIGLFLIFSLAPQQIGL
                     YQDLKAVEHSYHQLIRQNKALLTELNQHILTKFVNHQLSSSDLSKQYYHLRNRSQSQS
                     ELLVFDANSHMLFASNQHLGNFFRNAVYMTEVLKKARQRSSFLRISMDNEEGHYLLLI
                     KPIKIDHQVKGYSLLVMNGKDFLQLSHQIASDFVIADQFDNSFAFTNRTFMTSSLNKL
                     DSHFLKGYFIFHEHRAFILRKVALSPSITLYSYRPLIPVSIALLFSLMSSVMIYAILY
                     WKSKALATQIASSNSAAINQMILDMQAISRQEKNAIDLQSQDEFQYLSVQINQMISRL
                     QALHQKTLALEKQNVSFEKRMLEAQFNPHFLYNTLETILITSHYDSDLTEKIVLQLTR
                     LLRYSLDESQEAVCLGEDLAVLESYLLISQIRFEELRYTIAVEPALETLRVPKLFLLP
                     LIENAIKYGLRYRHDLVIEISVRQLADGIYFTVADNGPGISQKRQADIKELLHSEDSH
                     HGLVNSYRRLKHQFIKVELIFCQRDERFLLTYMVKE"
     gene            11413..12198
                     /locus_tag="TVB59_000528"
     CDS             11413..12198
                     /locus_tag="TVB59_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1009465.1"
                     /translation="MYKLLIVEDEHIIRKWLRYAIDYHALNILVIGEAKDGQQGAKLI
                     AEAKPDIVLTDINMPIMTAFEMFEATKEQSYAKIILSGYADFANAKSAIHYGVLEFLT
                     KPLERQALHDCLLTIIQKLQQQSQEQELSQQQDYLKLPQPNDQLPDVVQEMLSWIHEH
                     YQDKIMIGQLAHDLGYSESHLYHLAKKYLKMTFSDYINQYRLNRAIQLLIAEPDVMVY
                     QLAEAVGIYDYRYFDRVFKKYLGQTVKDFRETVLHQRSDRSSL"
     gene            12222..13232
                     /locus_tag="TVB59_000529"
     CDS             12222..13232
                     /locus_tag="TVB59_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEL1009466.1"
                     /translation="MAIVILGVIGSGLYAIWRHQAGPAPSKPRELVVLTPNSQNILTG
                     TIPAFEEKYGIKIRLIQGGTGQLIDRLQKDKDQLHADIFFGGNYTQFESHKELFEPYL
                     SKHIGFVLPDYLLQSEVATPYTLNGSVLIVNNELAKDMVITSYEDLLKPELKGKIAFA
                     DPNTSSSAFSQLTNILLAKGGYTNPKAWSYIKQLIHSMNSIKSASSSDVYQSVAEGKM
                     TVGLTYEDPCVNLLKSGANVSIVYPKEGTVFLPSAVAIVKQSKAKADAKLFINYMLSL
                     DVQRAFGQSTSNRPIRKDAKASQDMKPLDDIITLKEDYDYITRHKKDILERYNQLRKT
                     TD"
     gene            13485..15269
                     /gene="uvrC"
                     /locus_tag="TVB59_000530"
     CDS             13485..15269
                     /gene="uvrC"
                     /locus_tag="TVB59_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEL1009467.1"
                     /translation="MNELIKHKLELLPDSPGCYLHKDKAGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTELLVSEIADFEFIVTGSNTEALLLEINLIQENMPKYNIKLKDDKSYPFI
                     KITNEPFPRLLITRQIKKNDGLYFGPYPDAYTATEVKKLLDRIFPFKKCKNPVNKVCF
                     YYHLGQCQAHTICHTDKAYWDSLVADVKQFLNGKDDKIIDDLRSKMLEASHNQEFERA
                     AEYRDLISGIATMRTKQRVMSKDLQDRDIFGYFVDKGWMCVQVFFVRQGKLIQRDVNM
                     FPYYNEAEEDFLTYVGQFYSDQRHLIPKEVFIPETIDETLVAAIVPARIVKPQRGEKK
                     QLVALATKNARVSLQQKFDLLEKDLRKTSGAIEHLGQLLGIEKPVRIEAFDNSNIQGT
                     SPVAAMVVFVDGKPSKKDYRKFKIKTVIGPDDYASMREVIYRRYSRVKHEGLQAPDLI
                     IVDGGQGQVKAARDVIEHQLGLSIPVAGLQKNDKHQTHELLFGNPLAVVELPRNSEEF
                     FLLHRIQDEVHRFAITFHRQVRSKNAFSSKLDHIAGLGPKRKQLLLKRFKSMTALEQA
                     SLEEIQQLGIPKTVAEALFDHLTSKSEV"
     gene            15397..15999
                     /locus_tag="TVB59_000531"
     CDS             15397..15999
                     /locus_tag="TVB59_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEL1009468.1"
                     /translation="MKFLELNKKRHAIKRFNDKPVDYNDLRTAIEVATLAPSANNIQP
                     WKFVIVEEKKAELAKDLPLANKTQVEQAQYVIALFSDTDLIQRSRKIARIGVKSLPDN
                     LIGYYMETLPPRFATFTETQKGEYLAINAGLVAMNLVLALTDQKMASNIILGFNKKLT
                     NEILDIDPRFRPELLITVGYSDDKPEPSYRLPVDEIIERR"
     gene            16080..17489
                     /gene="pepV"
                     /locus_tag="TVB59_000532"
     CDS             16080..17489
                     /gene="pepV"
                     /locus_tag="TVB59_000532"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEL1009469.1"
                     /translation="MTTIDFKAEVDKRKEAMLEDLSNLLSINSERDDAKADAKHPFGP
                     GPVKALEFFLAMAERDGYQTRNIDNYAGDFEFGQGDEVLGIFAHLDVVPAGSGWETDP
                     YKPVIKDNRIYARGSSDDKGPTMACYYALKIIKELGLPVSKRVRFIVGTDEESGWGDM
                     DYYFAHNGLKNPDFGFSPDAEFPIINGEKGNITEYLHFVGQNAGAFVLHRFQGGLREN
                     MVPESATALISSPHELNVIEASLEQFLSEHAVTGSVKEADGLLEVTIIGKSAHGSTPE
                     AGVNGATLLAKFLNQFSFDGAAKAYLHIAGEVLHEDFTAEKLGLAYTDDKMGALSMNA
                     GVFSFAKDSDDNTIALNFRYPKGTNAAVLKAGLEQLPGLTKVTLSEHEHTPHYVPMDD
                     ELVSTLLSVYEKQTGLKGYEQVIGGGTFGRLLERGVAFGAMFPGDENTMHQANEYMPL
                     DNIYRSAAIYAEAIYELIK"
     gene            complement(17756..19132)
                     /gene="mnmE"
                     /locus_tag="TVB59_000533"
     CDS             complement(17756..19132)
                     /gene="mnmE"
                     /locus_tag="TVB59_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002888396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEL1009470.1"
                     /translation="MSITKEFDTIAAISTPLGEGAIGIVRLSGTKALDIAKSIFKGKD
                     LTTVASHTLNYGHIIKPSTGEVIDEVMVSVMLAPKTFTREDVIEINTHGGIAVTNDIL
                     QLLIKQGARMAEPGEFTKRAFLNGRIDLTQAEAVMDLIRAKTDKAMSIAIKQLDGSLS
                     QLISDTRQEILNTLAQVEVNIDYPEYDDVEEMTTALLRDKTREFQTLLEQLLRTAKRG
                     KILREGLSTAIIGRPNVGKSSLLNTLLREDKAIVTDIAGTTRDVIEEYVNIKGIPLKL
                     VDTAGIRETDDLVEQIGVERSKKALQEADLVLLVLNASEKLTEQDKALLALSQDSNRI
                     ILLNKTDLEQVIEKDQLPEEAIPISVLQNQNIDLIEDRINQIFFDHTGLIEQDATYLS
                     NARHISLIEQAVQSLEAVNEGLALGMPVDLLQIDLTRAWEILGEITGDAAPDELITQL
                     FSQFCLGK"
     gene            19404..19625
                     /locus_tag="TVB59_000534"
                     /pseudo
     CDS             19404..19625
                     /locus_tag="TVB59_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623017.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
     gene            19748..20062
                     /locus_tag="TVB59_000535"
     CDS             19748..20062
                     /locus_tag="TVB59_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04197 family type VII secretion effector"
                     /protein_id="HEL1009471.1"
                     /translation="MVVLQNNSSTASERATALARGVQALSSAGAVSKDMKTTVTGNRS
                     DASSAIDLSHNVSAQVVGIIASMSQHIQSVSASFQAMDLQLGKELGRLENRRRFSLND
                     PK"
     gene            20067..20399
                     /locus_tag="TVB59_000536"
     CDS             20067..20399
                     /locus_tag="TVB59_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3958 family protein"
                     /protein_id="HEL1009472.1"
                     /translation="MYQKERLDKRLETIAQELKRNEQRFEDYEELSNLAAQLLTAAAT
                     TFRSSSDSHLFEGALAEECYLKRKTQASLEQSHEELLGEQRRLYQEEEALTRQLKLVK
                     GKERANEH"
     gene            20401..21999
                     /locus_tag="TVB59_000537"
     CDS             20401..21999
                     /locus_tag="TVB59_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009473.1"
                     /translation="MYLGSSDQQASSVGKVLQQRITAYKSLQRALEQLVSSSPDLSGH
                     TYASAKRYSEQVLIPLMRGCILLDEAIKEACAAFPNDYRRQVDSVDLKESELVDQISR
                     SDRIIGRYVELIDLEYRQELPNYSYITNLKSGASNQRQVKRKLEEKLLKLREFDSNSR
                     HLFSSIAALAEAVNIGIRQTKTSWNGTSQTFTLPRALDLEWTKVVEKRWTQREEKASK
                     LKLQQAAEKLSRETGIKYEDAYRFVMDGVLSDENKNKIKSVKKLVKYTKGGLYIVSSG
                     RYYWKHSGKHYWKNTPNKTWNIWKASKNDPNFDKGGIKGKHFSKKGARYTDLPGIKQL
                     KKSETVQSLISKISKDNQGKLTKVGKGLKKVDKELSNISSKLKSYEHGRLNRDLKMMK
                     ENNLGKSLGKFGKVGKAASKVLKFAGKGLKVAGWVGAAINVKDSVETYKKKGYSNEQT
                     AALTARKVAVDTATTVVGSNIGRVTGAVIGQAVIPIPGVGAAIGSVAGSILGAMAGSW
                     IGSTINDNLDKNVKPKQSGRSLAW"
     gene            21993..22679
                     /locus_tag="TVB59_000538"
     CDS             21993..22679
                     /locus_tag="TVB59_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009474.1"
                     /translation="MVMLMRTLLFPVDNGLDSGLTGDGYAAEYDLWTGKVTWRQLGDG
                     KIKRQQKVAAIINLIAAAISPLVIMSIIFTAKSLKLFDVDTSTTIYRYAPLMVGLVFF
                     FSFELLMLAIRRLYPLAKEEPSLKRQHGYFKTMYDNTIRENDGVFNNLSVPFIGLYVA
                     FLIAFSVIPIFYSQYLQQNSFWSYLGNLVGSSILISLVPNFLWNVLVKQLIYIKLIRK
                     TKEKILKNET"
     gene            22701..23387
                     /locus_tag="TVB59_000539"
     CDS             22701..23387
                     /locus_tag="TVB59_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009475.1"
                     /translation="MVMLMRTLLFPIDNGMDNNLIGDGLSAEYDLWTGKVTWRQPSDD
                     KIRTQQKVAFVLNLIAGSLSPLAIFLFVIIVRRLGVFSGDTNSMIFKWAPLIVGFILF
                     ISFELLMLALRSRYTILEKEPDLDRQLYYYRTMYDNTIHDNSGVFNNLSVPYVGLYIT
                     LFLIFLIIPLCYHFYLHPSSFGDYLAALSVTSLLISLFPNFLWNGVLKHVIYVKLIRQ
                     TKERILKNET"
     gene            23409..24086
                     /locus_tag="TVB59_000540"
     CDS             23409..24086
                     /locus_tag="TVB59_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009476.1"
                     /translation="MVMLMRTLLFPVDNGMGTGLTGDGYAAEYDLWTGKVTWRQATKQ
                     TIEKQQALTSNLLIIASCLSPVTVAGMILLSRSFPIFEEDLSEKIDTYAPIILGVVLF
                     LAFETLMLAIRGRDPLAEKEPDLKRQHDYFEKMFDFAIRRNLSSDNLKTPYIATYFAF
                     GISLLCIPFSYYVYLNPEQFPNLDYGHLSILLVTSILISLVPNFLWNVLLKHIIYIKL
                     IRKTKGQ"
     gene            24093..24407
                     /locus_tag="TVB59_000541"
     CDS             24093..24407
                     /locus_tag="TVB59_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
                     /protein_id="HEL1009477.1"
                     /translation="MNKPEHILPIGTIVLTETGEIPLMIVSRASLFDDNGEIGYFDYA
                     AVPYPEGIGNDNEYLFFNHEDIADVIYFGYVNSNEQLFAEAYDDLVKTSGYRKLSLDH
                     HQ"
     gene            24855..25538
                     /gene="rpiA"
                     /locus_tag="TVB59_000542"
     CDS             24855..25538
                     /gene="rpiA"
                     /locus_tag="TVB59_000542"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEL1009478.1"
                     /translation="MEALKKIAGVTAAQYVTDGMTIGLGTGSTAYYFVEEIGRRIKEE
                     GLQVVGVTTSSVTTKQAEGLGIPLTSIDDIDCIDLTVDGADEVDKAFNGIKGGGAALL
                     MEKIVATPTKEYIWVVDESKLVDHLGAFKLPVEVVQYGADRLFRVFERAGYKPSFRMK
                     GDKRLITDMQNFIIDLNLGCIENPCEFGRLLDQTVGVVEHGLFNGMVDKVIVAGQAGV
                     TVLEANQST"
     gene            25616..26827
                     /locus_tag="TVB59_000543"
     CDS             25616..26827
                     /locus_tag="TVB59_000543"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEL1009479.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDADKFFNAGVADTDSDTLGHISE
                     TAGLAVPNMAKIGLGHIPRPVPLKTVPAEADPTGYVTKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWDGFPEEIIQKIEAFSGRKVIREANKPYSGTKVIDDFGPRQMETGELIV
                     YTSADPVLQIAAHEEVIPVEELYRICEYARSITLERPALLGRIIARPYIGEPGSFTRT
                     ANRRDYAVSPFQDTVLNKLADAGISTYAVGKINDIFNGSGITNDMGHNKSNSHGIDTL
                     IKSLQLPAFTKGLSFTNLVDFDASFGHRRDPEGYRDCLHEFDRRLPEIIANMKDDDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSASCTGAGVIPQGHFADISATIAENFGVDTA
                     MIGTSFLADLV"
     gene            27040..27849
                     /locus_tag="TVB59_000544"
     CDS             27040..27849
                     /locus_tag="TVB59_000544"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEL1009480.1"
                     /translation="MTLLEKIRETQAFLESKGIDKPEFGLILGSGLGELANEVEQAIV
                     IDYADIPNWGKSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPMEVVTFPVRVMKA
                     LGCHSLLVTNAAGGIGYGPGTLMLINDHINMTGTNPLIGENLDEFGPRFPDMSDAYTA
                     AYRETARSVAEKLGLDLQEGVYLGCSGPTYETPAEIRAFKVMGADAVGMSTVPEVIIA
                     AHSGLKVLGISAITNFAAGFQSELNHEEVVEVTERIKENFKGLVKAILAEL"
     gene            27940..28725
                     /locus_tag="TVB59_000545"
     CDS             27940..28725
                     /locus_tag="TVB59_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytR family transcriptional regulator"
                     /protein_id="HEL1009481.1"
                     /translation="MTDMEHTISILLEVYAYSHAYKIARTLPDFSPKVLYLLELLKER
                     RELNVAYAFQHRAENRLIEDRHQVKLLLNEAQEEEQTANYLLDLAAKVKNGEIIDFVR
                     SVSPVLYRLFLRLLEQAVPDVQSYIIDTKNDQYDTWNFKAMEKADNDLFRSYLAQRQP
                     RHVTTRSLADLLVLSELPADIKRLVVVLRQFEKSVRNPLAHLIKPFDEEELYRTTHFS
                     SQAFLDGLIRLAVFSGVNYIKEPFYFDVVNAVIEKELLDSAKP"
     gene            complement(28858..29766)
                     /locus_tag="TVB59_000546"
     CDS             complement(28858..29766)
                     /locus_tag="TVB59_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEL1009482.1"
                     /translation="MRIQQLQYIIKIVECGSMNEAAKQLFITQPSLSNAVKELEQEMG
                     ITIFIRNPKGITLTKDGVEFLSYARQIIEQTALLEDRYKNHNTSRELFSVSSQHYAFV
                     VNAFVSLLKRADMTQYELFLRETRTWEIIDDVKNFRSEIGVLFINDYNRDVLTKLFEE
                     NHLTVSTLFKTTPHIFISKSNPLANKTSLTIDDLLDFPYLSYDQGIHNSFYFSEEMMA
                     HIPHSKSIVVSDRATLFNLMIGLNGYTVASGILNTNLNGDQIVAIPLDVPDVIEIVFI
                     KHEKANLSKMGERFIDYLLEEISFNH"
     gene            30106..30555
                     /locus_tag="TVB59_000547"
     CDS             30106..30555
                     /locus_tag="TVB59_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009483.1"
                     /translation="MTGQSSHQVLIQKLLVSTHYLTLFRDELKLVERTPSILGSEFPV
                     SLVQTELGDIITLVDTLNKQQRLIESTFWYEESAFKLMNKALDIVDNWIKGIDGLIKL
                     CQSKEVFQAIVGDKRTRVFGVLIDVFSSLKISTMSLKEFAAPAALCH"
     gene            31176..31868
                     /gene="pyrF"
                     /locus_tag="TVB59_000548"
     CDS             31176..31868
                     /gene="pyrF"
                     /locus_tag="TVB59_000548"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEL1009484.1"
                     /translation="MREERPIIALDFPSFEEVKSFLSLFPADERLYVKIGMELYYAEG
                     PDIVRYVKSLGHSVFLDLKLHDIPNTVKSTMAVLSRLGIDMTTVQAAGGVEMLRAARE
                     GLGQGPILIAVTQLTSTSEEQMREDQNIQSTLLASVLHYAKRTAQAKLDGVVCSAHEV
                     KAIKSEVPAGFVCLTPGIRPTGADIGDQKRVMTPHQARAIGSDYIVLGRPITQATDPV
                     KAYHQIKAEWNR"
     gene            31928..32563
                     /locus_tag="TVB59_000549"
     CDS             31928..32563
                     /locus_tag="TVB59_000549"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEL1009485.1"
                     /translation="MTLAAQIATDLLEIKAVYLRPKEPFTWASGITSPIYTDNRITLS
                     YPKTRSLIENGFVETIKAVFPEVEVIAGTATAGIPHGAIVADKMDLPFAYIRSKPKDH
                     GAGNQIEGHVRCGQKMVIIEDLISTGGSVLEAAAAASREGADVLGVVAIFTYELPVAS
                     INFEKAGLSLVTLSNYSDLIKVAKAKGYIDADGLALLKRFKEDQKHWQHES"
     gene            32615..33358
                     /locus_tag="TVB59_000550"
     CDS             32615..33358
                     /locus_tag="TVB59_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1009486.1"
                     /translation="MTYKDLLEIGETSYYQTDRLTYYKNPVVSERYFDNYLSYRSMPS
                     LADLKKDLAYVAKEQQDYPSHYAFLFFAENEELSTDMRAYLTDHHFSLEKHLIFTNEL
                     AKLHLKERDISPVTIEQLSETSFSAYLAYKYQANLAYGETYANQCKADNEANLLTNGS
                     TIYLAIKEGKIIGDITAWECGDYIEMDDFSVDEAYRGRGIGTALQRKASQGYKKVILI
                     SEEANRAMYEHQGYQEVAYYWTALKTSTR"
     gene            33593..35047
                     /locus_tag="TVB59_000551"
     CDS             33593..35047
                     /locus_tag="TVB59_000551"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HEL1009487.1"
                     /translation="MIFKDATEMAQAVREGRVSPSALVRDTIKKAQALNPELNAITSE
                     RFSEALAEAAARDFSGKPFAGVPIFLKDLGQEQEGQLATAGSVLFKDYRASKTDYVVQ
                     RLEELGFIILGRSNTPEFGFKNISDSRLHGPVNLPQDKSRNAGGSSGGAAALVSSGIT
                     LLAPASDGGGSIRIPASFNGLIGLKPSRGRVPVGPGSYRGWQGASVHFALTRSIRDTS
                     RLLYHLQVYQVESPFPLVPLTKEELFHPLDRPLRIALYDHMIDGTTASIDAQTALTEA
                     CHFLKEMGHEVVRLDKLPLDIPKVMRDYYLMTSVETAAMFADSQEALGRQVTKADMEV
                     MTWAIYQAGKDILASVYSQALQRWDHYSAEMASFHEQYDLLLTFTANTPAPKHGQFQP
                     SKELIDKLAKAECYPSSQRLALVEAMFEQSLFITPYTALANLTGQPALSLPTYETSAG
                     LPMGIQLIAAKGREDLLLGIARQFERAGLLKLPG"
     gene            35167..36033
                     /locus_tag="TVB59_000552"
     CDS             35167..36033
                     /locus_tag="TVB59_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEL1009488.1"
                     /translation="MKKGVALLSVSLASLLLAACGSQPSAQKTSWEKIKDKGVLKVAT
                     PATYQPTSYYNDANELVGYEVDLMKEIGKRLDLKVKFIETGYDQAFTSVDSGRVDVSL
                     NNFDITAKRQKKYNISTPYKYGVGGMIVRADGSSGISKADLSDWKGKKAAGASGTEYM
                     KVAKKQGAELVTYDNVTGDVYLNDVANGRTDFIPNDYPAQKLFVDYMKSQNPNLNVKM
                     SDVLYNPTAQGIIMSKKDDTLKKKIDAVIKDMKQDGSLKTISKTYYAGQDLTVPFGKD
                     KKIPVIDASDVD"
     gene            36061..36714
                     /locus_tag="TVB59_000553"
     CDS             36061..36714
                     /locus_tag="TVB59_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEL1009489.1"
                     /translation="MLNLRLILESLGFVLSGLPYTLGISFLSFLTGLLLGLLLAFLRR
                     STSHFSHYLVRSYVSIMRGVPMIVVLFVLYFGLPYYGLELSALLCAYLGFSLVSAAYI
                     SEVFRASIDAIDQGQWEAARALGLPYVSIVKHVILPQAFRIAIPPLGNVVIDMVKSSS
                     LAAMITVPDIFQKAKIIGGREWDYMSMYILVAFIYWVIAFLLERCQGFLEKRLRLLS"
     gene            36845..37252
                     /locus_tag="TVB59_000554"
     CDS             36845..37252
                     /locus_tag="TVB59_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1009490.1"
                     /translation="MADSIVFRKNHMISTQAFARVLEASGIKRPTKDEARLSQMLKHS
                     NYLWTAWEGDKLVGVARALTDYAYVCYISDLAVDQAYQGQGIGKQLLSFISEDLGDAV
                     ALVLLSAPSAMSYYPKLGFEQSDKAFIIPRKPF"
     gene            37264..37917
                     /locus_tag="TVB59_000555"
     CDS             37264..37917
                     /locus_tag="TVB59_000555"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEL1009491.1"
                     /translation="MTHSAWHDEIKQVLPKDYYRRINRFLDEVYATGVVYPPRDNVFK
                     ALQVTPLEETRVLILGQDPYHGPLQAQGLSFSVPDSIPAPPSLQNILEELAADIGVRN
                     HHDLSSWAEQGVLLLNACLTVPEGRANGHAGLIWEPFTDAVIKVLNAKDRPVVFILWG
                     AYARRKKALITNPIHHVIESPHPSPLSAYRGFFGSKPFSRANAILEKEGLGQIDWLR"
     gene            38149..39423
                     /locus_tag="TVB59_000556"
     CDS             38149..39423
                     /locus_tag="TVB59_000556"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEL1009492.1"
                     /translation="MLLIKNGRVMDPKSQLDQVADVLIDNGRILRIAPDIEHDEVEQI
                     DASGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGVTTVVMMANTNPVISDTE
                     TLQAVLASAAKEKINIYTNASVTKRFNGQELTDFKALLAAGAVSFSDDGIPLESSKVL
                     KEALDLAKANKTFIALHEEDPQLNGVLGFNEHIAKDHFHFCGATGVAEYSMIARDVMI
                     AYDRQAHVHIQHLSKAESVKVVAFAQQLGAKVTAEATPQHFSKTEDLLRLAGANAKMN
                     PPLRTEQDRLAVIEGLKSGVIAIIATDHAPHHRDEKAVADLTKAPSGMTGLETSLSLG
                     LTNLVEPSHLSLMALLEKMTINPASLYSFDAGYLAESGPADLVIFADKEERLVTEAFA
                     SKASNSPFIGETLKGVVKYTIAKGQIVYQADN"
     gene            complement(39477..40124)
                     /gene="plsY"
                     /locus_tag="TVB59_000557"
     CDS             complement(39477..40124)
                     /gene="plsY"
                     /locus_tag="TVB59_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEL1009493.1"
                     /translation="MKLILLILTAYLLGSIPTGLWIGQYFYNINLREHGSGNTGTTNT
                     FRILGLKAGAATLLIDIFKGTLATLLPVLVGASNISPITIGFFAVLGHTFPIFAGFKG
                     GKAVATSAGVLLGFAPLYLLFLAAVFVLTLYLFSMISLASLTASVVAVISVLTFPAAH
                     FLLPSYDWLLTITIVVLAAIIILRHQDNMKRIKQQSENLIPWGLNLSKQQPASHH"
     gene            40257..42206
                     /gene="parE"
                     /locus_tag="TVB59_000558"
     CDS             40257..42206
                     /gene="parE"
                     /locus_tag="TVB59_000558"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEL1009494.1"
                     /translation="MAKKEISITNYNDDAIQVLEGLEAVRKRPGMYIGSTDATGLHHL
                     IWEIVDNAVDEALSGFGNEIDVTLNKDGSATISDSGRGMPTGQHALGIPTVQVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGRPVTGLE
                     KIATAPKSKSGTRVTFMPDDKIFSTTEFKWNTIAERLKESAFLLKTVKMTLTDLRGDD
                     PVVEEFHYENGVQDFVAYLNEDKETLTPVIYMEGQEQDFQVEVALQYNDGFSDNILSF
                     VNNVRTKDGGSHETGLKSAITKAMNDYARKTSLLKEKDKNLEGSDYREGLSAVLSILV
                     PEQHLQFEGQTKDKLGSPLARPIVESIVSEKLTFFLLENGELAGHLIRKAIKARDARE
                     AARRARDESRNGKKNKKDKGLLSGKLTPAQSKNPKKNELYLVEGDSAGGSAKQGRDRK
                     FQAILPLRGKVLNTEKAKMADILKNEEINTMVYTIGAGVGADFNLDDINYDKIIIMTD
                     ADTDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKSEKVSYAWTDGEL
                     EDLRKEFGKGASLQRYKGLGEMNADQLWETTMDPDTRTLIRVTIDDLARAERRVSVLM
                     GDKAAPRRQWIEDNVTFTLEENTVF"
     gene            42308..43123
                     /locus_tag="TVB59_000559"
     CDS             42308..43123
                     /locus_tag="TVB59_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATPase"
                     /protein_id="HEL1009495.1"
                     /translation="MKLDICQQSYSLQWGGTYYFALTDYPNIKAWELEKLAAFCAYEK
                     WNHRQTDISCQDSKLLEEVHQFLEAHACAYLFRPSCKLVASTFNINGEAVCCPYLSHT
                     CTVAAALSIFKTGRLLSAVRAFGVTAQELARSDRNAAGDPADYFHYVMLGWSNTTSGY
                     RLAMERLLNRMPNEKDLREHFVPGVSFHYSYSDICQMKGYVFDGYHPAKIKDELSLEE
                     LQACIIPKSWQQRFEAIIPKALRSRVHYLDYKGEGLVEWSDRVYQLLRVISDS"
     gene            43598..46057
                     /gene="parC"
                     /locus_tag="TVB59_000560"
     CDS             43598..46057
                     /gene="parC"
                     /locus_tag="TVB59_000560"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEL1009496.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQERALPDIRDGLKPVQRRI
                     LYSMNKDGNTFEKGYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQDWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIDKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSSGISAGYATDIPPHNLSEVIDAVIYMIDHPNAKLDKLMELLPGPDFPTGGI
                     IQGAAEIKKAYETGKSRVVVRSRTEIEDLKGGKQQIIVTELPYEVNKAVLVKKIDDVR
                     VNNKVPDIAEVRDESDRTGLRIAIELKKDADSQTILNYLLKYTELQVNYNFNMVAIDH
                     FTPRQVGLQKILSSYIAHRKSIIIKRSQFDKEKAEKRLHIVEGLIRVLSILDEIIALI
                     RASDNKADAKENLKVSYDFSEEQAEAIVTLQLYRLTNTDIVTLQQEEHDLRELITTLS
                     AIIGDEATMYNVMKRELREVKKKFAGPRLSELQAESQAIEIDSASLILEEETFVSVTQ
                     GGYIKRTSPRSFHASSLEEIGKRDDDHLIFVKQAKTTDHLLLFTNLGNVIYRPVYELT
                     DLRWKDIGEHLSQAIANFAADELVIYAELIQSFEEGLYISVTQHGLIKRFERKELTPW
                     RTYKSKSIKYAKLKDIDDRIVAIAPIIMEDLLLVTQQGYALRFSSQEIPIQGLKAAGV
                     KGINLKAQDYLVSACPVNADSFFVLTQRGALKRVAIADIPQTSRANRGLPVLRELKTK
                     PHRVFLAGMVKGDTTTGTIDLFTHDSEDTASDQQLEVISKTGQQYQLALNSLSLSDRT
                     SNGSFISESISDQEVAAARLI"
     gene            46155..47180
                     /locus_tag="TVB59_000561"
     CDS             46155..47180
                     /locus_tag="TVB59_000561"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEL1009497.1"
                     /translation="MMTTAIDWENLGFEYRKLPFRYVSYYKDGKWDAGRLTEDATLHI
                     SESAPALHYGQQAFEGLKAYRTKNGSIQLFRPDRNAARLQATADRLLMPQVSTEQFID
                     AVKQVVKANEDFVPPYGTGATLYLRPLLIGVGDIIGVKPANEYIFIVFAMPVGNYFKG
                     GLAPTNFIVSEDYDRAAPYGTGAAKVGGNYAGSLLPGKAAKTAGYSDVIYLDPATHTK
                     IEEVGAANFFGITANNEFITPLSPSILPSITKYSLLQLAEERLGMTAIEGDVPINDLD
                     RFVEAGACGTAAVISPIGGIQYQDKLHVFYSETEVGPVTRRLYDELVGIQFGDIEAPE
                     GWIVAID"
     gene            47248..47478
                     /locus_tag="TVB59_000562"
     CDS             47248..47478
                     /locus_tag="TVB59_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEL1009498.1"
                     /translation="MSKKEKKIELQLCDQQVTVNNTKIDGYQLQIGKRVVGEIAELDG
                     KFAVLKDSTVDAFFKTLEQAVENIIENYNLNH"
     gene            47539..47619
                     /locus_tag="TVB59_000563"
     tRNA            47539..47619
                     /locus_tag="TVB59_000563"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:47573..47575,aa:Tyr,seq:gta)
     gene            47658..47729
                     /locus_tag="TVB59_000564"
     tRNA            47658..47729
                     /locus_tag="TVB59_000564"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:47690..47692,aa:Gln,seq:ttg)
     gene            47857..49059
                     /gene="rpsA"
                     /locus_tag="TVB59_000565"
     CDS             47857..49059
                     /gene="rpsA"
                     /locus_tag="TVB59_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002997242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEL1009499.1"
                     /translation="MNEFEDLLNSVSEVNPGDVVTAEVLTVDNGQANVVIEGTGVEGV
                     LTLRELTNDREADINDYVKAGDTVEVLVLRQVVGKDTDTVTFLVSKKRLEARKAWDKL
                     IGREGEVVTVKGTRAVKGGLSVEFEGLRGFIPASMIDTRFVRNTEKFVGQEFDAKIKE
                     VDAAENRFILSRREVVEEAAKQARDKVFSTLSEGSVVTGTVARLTSFGAFIDLGGVDG
                     LVHVTELSHERNVSPKSVVSVGEEVEVKVLALDEEAGRVSLSLKATTPGPWDGVEQKL
                     AQGDVIEGKVKRLTDFGAFVEVLPGIDGLVHISQISHKRVENPKDVLTVGQEVTVKVL
                     DVNAADERVSLSIKALEERPAQAEGEKEEKRQSRPRHQKREAKRDYELPETQTGFSMA
                     DLFGDIEL"
BASE COUNT        14118 a         9098 c        11456 g        14398 t
ORIGIN      
        1 ggcataattt cacctcgtga cgataccgtt acttcttttt gaccaagaaa agaaaatgaa
       61 agtaaaaata tgacgaataa tgttaatggt ataataagaa ttatcgcaaa attatgatag
      121 cgtcgctgat aaaattcagc acttctaaac agatttggat tcatgaatat ctccttactt
      181 actaaataaa tgatgataga agccttgatg cgtcattaat tcgttatgcg aacctatctc
      241 gattattttt cctttatcaa gtacaacaat ttggctagta cgttcagcag tactaagacg
      301 atgggcaacg aaaataatcg ttttctcggt cattgacatt aggttatcaa tcactttttt
      361 ctccgttaag acatctagtc cgcttgtcgc ctcatcgaga attagaatag gagacttggt
      421 taataatgct ctagctaatg caattctctg tttttgtcca ccagaaaatc ctgccccatc
      481 agatagttct gtctgatagc ccataggcat ttgttcaata tcttctctaa tttctgccat
      541 atcacaggca ttgataatat cctcttgagt aatcgcttgg tttgcaccga gagtaagatt
      601 ttctaaaatt gatccactaa aaatataagc ttgttgaggc agatattggt tatcgaaacg
      661 tcctaaatgg taatctgaca aatctatcaa attatctcaa acggttgaat ttaagtctta
      721 agcggtaaat ttttcccatt taggacgttt cgatgactgt ttaggaaatg gagaacaaat
      781 tttaaccgaa agtgttatac taagtctgtc aagcttgcaa ccggacaaaa taaaaacaca
      841 tataaaggag gtattcgtca tggatacaaa atttacagcg ttgactgaag agcaattgaa
      901 atcagttgag ggtggaaaaa atggagttgt aaaattacct ggagggaccg gtgtatattg
      961 ttggaataca ggaaaaaata gtgcaaaatg tggtatggac tggagtgtgg caggaccata
     1021 tgttggtaag ataattgtca atggttgggt taaccatgga ccttgggcaa gtcgtccata
     1081 attttaattt atatagagag gtgtgaaatc atgaatgaaa gagatttagt acagctgata
     1141 gaacagactc taaaagatga agaggtgcaa aataatgtca cttataggaa tcttttggaa
     1201 gaaagtctcc agcaattatc actcaaaaag cctgtgtatt tagttagtac caggttagca
     1261 ggacatattt caacctatct aatgacaaat cattatgagg caccaaaagc gattatagtt
     1321 cttgctcaat ctatcgcatc aaccccagct aaacatagag gtttaatttc tataccattc
     1381 tggttaagta atatatttcg ttaaaaaata ttttcagatc aggatttaga aggagttgta
     1441 gattggcaat gcactcataa aataagacac attttttgga gttttttgct tgaactccta
     1501 acttttacat tagtctataa acagtcaaag gaagttcttt caatctctca aattgcaaaa
     1561 caattttggc tatattttaa aagtacaatt ttgattccaa ttttagttac aatcattctt
     1621 ataaaggaga ttttgtcaag tacattacaa ataatgattt atttttacct taatgttgtt
     1681 gtcatgtgct acgctattgg aatgatctta tcgttaggtt atgtgatttc acccaagcac
     1741 tctatattca ataaaattaa aaatataaaa ttaaataata gagtatccca agagattgcc
     1801 gaatcccaat ttaccagtct tttagagcga agagcgactt gaagaaactg ataaatttat
     1861 ttggttttct gctaaaaatc ctgccaaaaa atctttggca ggatttttat tttactaaga
     1921 gatatttagg agtggctttg tcatttaatg cagattatga tatagcagga gacatattgt
     1981 tgaagctgtc tatgtcactt ttggtggcag gtaggtctta ttggaattgg tgacttatga
     2041 catttatcgg tggctgtaag cgtttgactt tttcacgttt catagtggtc cgctctggaa
     2101 tgagtgggta ttttttcaga atatgatcaa agatagatga catgttttac agcaggctat
     2161 agctggtatg atttgtttaa aaaatcaagg ccaatgataa gtgctgggtg acataagtct
     2221 tatggcttta cttcttgtta gcttgtgtca gcaggtgctg agtcaatcgt tgtaggaatt
     2281 atcgtaaacc taacagtagc tgctgttcta tttgtttatt ttctggtttc tattcaaatt
     2341 tctaaaatgc tagggtaaca aatatgaaac aagcaagtgg cgtactgcga acagcttgat
     2401 aacttattgc ctgcttaaag agggtgctgt tatgcttggt tttattaggc ttatggcatg
     2461 ggattaaaag gttgctgtag cgccattgtc attattttgg tacaataata ggtaaaagac
     2521 taaatgtata ggaaaataga atgaacagtc aagaattaaa aaaacgtcag gagaacattc
     2581 gtaatttctc tattattgcc cacattgatc atggtaagtc gactcttgct gaccggattt
     2641 tggaaaagac agaaacggtt tcaagtcgtg aaatgcaggc acagctcctt gattcaatgg
     2701 acttggagcg ggagcgtggg attaccatca agctaaatgc gattgagctg aattataagg
     2761 ctaagaatgg tcaagattat atttttcact tgattgatac accagggcat gtggacttta
     2821 cctatgaggt gtcccggtca ctagctgcct gtgagggtgc tgttttagtg gtggatgctg
     2881 ctcaggggat tgaggcacag accctagcaa atgtctatct ggcgcttgat aatgatttgg
     2941 aaattcttcc agtgatcaac aagatcgatt tgccagcagc tgatcctgag cgggttcgtc
     3001 aggaaattga ggacgtgatt ggtctagatg cttcggaggc tgtacttgcc tctgcaaagt
     3061 ctgggattgg tattgaagat attttagagc aaattgttga aaaggttccc gcaccgtctg
     3121 gtgatgttga tcaaccgctg caggccttga tttttgattc ggtttatgat gcttatcgtg
     3181 gggttatcct gcaggtgcgt gttgtcaatg gtatggtcaa gccaggtgat acgatccaaa
     3241 tgatgtcaaa tggaaaaacc tttgatgtga ctgaggtggg gatttttacc cctaaggcta
     3301 ttggtaggga ttttcttgct actggtgatg ttggctatat tgcggcctca atcaagacag
     3361 ttgctgatac gcgtgtcggt gatacggtca ctctggctac aaatcctgca gcagagccct
     3421 tgcatggcta caagcagatg aatccaatgg tgtttgcagg gatttacccg attgagtcta
     3481 acaaatacaa tgatcttcgt gaggccttag aaaagcttca gcttaatgac gctagcttac
     3541 agtttgagcc tgaaacctcg caagcattgg gctttggttt tcgttgtggc tttcttgggc
     3601 tgttgcacat ggatgtcatt caagagcgtt tggagcgtga attcaacatt gatttgatca
     3661 tgacagctcc gtctgttgtc tatcatgtta atataactga tggtgacatg cttgaggtct
     3721 ctaacccgtc agaatttcct gatccaacta aggtagatag tattgaggag ccttatgtca
     3781 aagcccagat catggtgccg caggagtttg ttggtgctgt tatggagttg gcccagcgta
     3841 agcgtggaga ttttgtgacg atggattata ttgatgacaa tcgtgtcaat gtgatttacc
     3901 atattccctt agctgaaatt gtgtttgact tctttgataa gctgaaatca tcaacgcgag
     3961 gctatgctag ctttgactat gaaattgctg aataccgtcg ctcgcagctg gtgaaaatgg
     4021 atattttgtt gaatggtgat aaggttgacg ctcttagctt tattgttcat agagcatttg
     4081 cctatgagcg cggtaagctg attgttgaga aattaaagaa aattattcct cgtcagcaat
     4141 ttgaggtgcc gattcaagcg gctattggtc aaaagattgt ggctcgctct gatatcaagg
     4201 ccttacgcaa aaacgttctt gctaaatgct atggtggcga tgtttcccgt aagcgtaagt
     4261 tgcttgaaaa gcaaaaggct ggtaagaagc gtatgaaggc tattggctct gttgaggtgc
     4321 cgcaggaggc cttcttgagc gtcctatcaa tggacgatga gagtaagaaa tagtgacatg
     4381 ttaagtaagg agctggatca tgcgatctgg ctcttatgct tgatgtctcg ataggctaga
     4441 aaatagggct tgtgtcatga taggcttgta tgtttgagat ggtttggaac ataatgactc
     4501 tatcatatct gtagtggatt gacaaagagc cgtaaaccat tgatatttgg atagttaatt
     4561 tcgagttatt ctgtagtact ctcttaaggt ctttcatatg agcttttcta atgttggttt
     4621 ggttgctttt catgataagt catatgggat ttttttggta tactgaaaaa agcctatagc
     4681 ctctacagtg gcgtctccct ctacagagat gatagagcca gagtgattgt tacgatctgg
     4741 agatgtggcg ctaggcatta atgcaggagg acttaaccag attgctgtta ggcttgaaat
     4801 cttaagctat attgattgtc agcttgattt agagaagtct aagtttatgg ctcacaaatg
     4861 ctcggtcttt ttgttacaat agagttaatc agttattttt ataaggagac agctatggaa
     4921 tctaaggaag agcttcgcca gcgtattgga gatttggctt ttgaggtgac tcagcatgca
     4981 gcgaccgaaa gagcctttac aggtcagtat gatgattttt ttgagaaggg gatttatgtt
     5041 gatgtggtga gcggagaggt gctcttttcc tctttggata aattcaattc tggctgcggc
     5101 tggcctgcat tttctaagcc gattcagcat cgtatggtaa ccaatcacca tgattcatca
     5161 catggcatgc ggcgtgttga ggttaaaagc cgcgaggctg gctcccattt ggggcatgtt
     5221 tttaatgatg gccctaagga ggcaggaggc ttacgctatt gcattaactc cgccgcgctg
     5281 aaatttatcc cctatgatca aatggagcaa gagggctacg ccgaatggtt agggattttt
     5341 gataagagct aggaattgct agcggccaat gaaaaggtag agctcttagc caatgctagt
     5401 ggctaaatca aagaaataaa aaggtggcta aagtacatag aaaaaagagg taagcagatt
     5461 ggcaggtggt caatctgctt tttgtgagga gactttcagc ctgctttgcg ctaaaaagta
     5521 tgaaaccaat aaaccaccta ctatgcgggt gtgtgtcggt ggttagctta agttttttca
     5581 gttcggtttt acaagcttct ctaaaaggac tataatagct aatggaaaag gagattcata
     5641 tgctaacatc tttagaaaaa ttaccgggcg ttttactgtg cttgctgtta gcactgcctg
     5701 cctggtattt gggaagctta tttcctatta ttggagcgcc agtttttgct attttattgg
     5761 gaatgctatt ggcgcttgtc tatcagaagc gtgactacac taaatctgga atcgcattga
     5821 cgtccaaata tattttgcag ctggctgtgg ttttcttggg ctttggctta aacgtgacac
     5881 aggttttagt ggttggcttg caatccctgc cgattattgt agtaacgatt gtgactgcct
     5941 tgggcataag ctatttgttc aaaagatggt taaggctacc agccaagaca gctatcttag
     6001 ttggtgtggg ctcgtctatt tgtggtggct ctgctattgc agccacagct cctgtcattg
     6061 atgcgcagga cgatgacatt gccaaggcca tttcggttat ttttttgttt aatatcttgg
     6121 cggccttgct atttccagct ttgggtcaga tgcttggctt atcaaatcat ggctttgcta
     6181 tttttgctgg aacagcagtc aatgatacct catctgtaac agctacagcg acagcctggg
     6241 acgctattca ccagtctaat acgctagatg gggcaaccat tgtcaaatta accagaacgc
     6301 tggctattat tcccataaca cttggcttat ctatttacca aaccaagagc aggcaggcac
     6361 atacgacaga gggttccttt agcctcagaa aggcttttcc gacctttatt gtctttttct
     6421 tgctagcttc cttgataacc acctttgctg ctagcttagg tctgccaatg gcaatctttc
     6481 atcagcttaa gctactctca aaattcttta tcgttatggc catggcagcg atcggactta
     6541 ataccaatct agtgacctta gtcaaaactg gtggtaaggc cattttgctg ggtgggattt
     6601 gctggctagc gatcacatca gttagcttag caatgcaggc agctttgggg agctggtaac
     6661 tgatgagaat agctggtgat acgctgcttt ataggaaaag caaagccctt gctgctccta
     6721 aaaaagcttg ttagagcagc tcacttagct gttaagtgtg gcttggtggg gtgtaagtag
     6781 gctctatcag ttagaaaagc catcagaaca aacgctatca ttaagctgaa gccggggaaa
     6841 ctcggctttt acgttatgca gaattgtcta catattgaat aggattatcc attttaaaaa
     6901 cgttttcatt tgatagaata caattatagc ttggttatta gggtaaacga gattgaactt
     6961 cttatctggt ttagcttaag taaaaaagca gttggaggaa gcatgaaacg taaattttta
     7021 attggtagtc atgggagaat ggccagtgga ttgaaaagct ctattgacat tttggctggt
     7081 agaggtcagg aattacaagt cattgacgct tatattgatg atagtgatta tactgagcag
     7141 gtattgacct ttatcgaaga tgtagcagct gacgagcagg cactgatttt tacagattta
     7201 ttaggtggca gtgttaatca aaaaatagta actgccctaa tggacagtgg caaggaaaat
     7261 atctttttga tttcaaatag taatcttgca gccttgctat cgttgatgtt tttaaagcca
     7321 gaagaagagc tgacaaaaga cgagattgta gcaacgatta acgattctca ggtgcagctg
     7381 gtggatctag ctccagcgac agccgcagaa gatgactttt ttaattgagg aggaaaaatg
     7441 aaatgattac acaaattcgt gttgacgaca gattgattca tggacaggtt gctgttgttt
     7501 ggaccaagga gcttaatgcc cctttgcttg tggtggctaa cgatgaggct gctaaaaatg
     7561 agattacaca aatgactcta aaaatggcag ttcctaatgg catgaaatta ttgattcgct
     7621 ctgttgagga ctctatcaag gttttcaatg atccacgcgc agtggataag cgtatttttg
     7681 tcattgtcag ctcgattaag gatgcttgcc agattgcaaa gcaggtgaag gacttagagg
     7741 ctgttaacgt tgcaaatgta gggcgctttg acaagtcaga cccagcaact aaggtcaaat
     7801 tggcttcaag cctattgtta aatccggctg aattagaagc agcaaaagag ctggttagcc
     7861 tgcctaacct agatgttttc aatcaggtac tgccatctaa tagcaaggtt agcctgagcc
     7921 agctcatcaa ataaagaaag gtgtaatgac tatgttagta ccagcaacaa tggcagcctt
     7981 agctgtattg atttgtttcg ggggaaatta tttaactggc caaagcatga tggaaagacc
     8041 gcttgtggtt ggtttggtga caggattgct cttaggagat atgaaggtcg gtatcttgat
     8101 gggagcgtca ctagaggcac ttttcctagg aaatgttaac attggtggtg tcattgcagc
     8161 agagcctgta acagcaacag ctatggcaac gacctttacc atcatttcac atattgatca
     8221 aaaagcagct atgacgctag ctgttccgat tggcatgcta gcagcctttg tggtcatgtt
     8281 tttgaaaaat gtttttatga atatctttgc gccaatggtt gataaggcag cagcggcaaa
     8341 ccatcagggc aagcttgtca tgctgcacta tggcacatgg attgtctatt atttgattat
     8401 tgcctctatt tcctttatcg gtatcctagt tggaagcgga cctgttaacg cctttgttga
     8461 gcatattcca caaaatctga tgaatgggct aagtgcagct ggtggtcttc ttccagcagt
     8521 cggatttgcc atgctgatga agctcttatg gacaaataag ctagcagttt tcttcctatt
     8581 aggctttgtg ttgacagctt atttgaagct accagcagta gctgtggctg cacttggtgc
     8641 agttatctgt gtgatcagct cgcagcgtga tttagagtta gatgctatta ctaagggagc
     8701 tatcagtaac caaagcagct ttgactctaa agaatcagaa gaggaggact tctttgcatg
     8761 agatctcaag acaatttaac taaagaagaa agaaaaatgc tacgctctgt tttctggcgt
     8821 tcatggacca tgaatgctag tcgtacagga gctacgcaat accacgctgt tggggttatc
     8881 tataccttgt tgcctgttat caatctcttt tataagacag ataaggataa ggcagacgct
     8941 cttgttcgtc acaccacttg gtttaatgcg accatgcata ttaataactt tatcatgggc
     9001 ttggttgcct caatggaaaa gaaaaacagt gaggatccaa cctttgacgc tagtgctatt
     9061 acagcggtca aggcttcctt gatgggacct atttctggtg ttggagattc ctttttctgg
     9121 ggtattttga gggtcattgc agctggtatt gggatttcac ttgctagcac aggctcagcg
     9181 atgggagcag tagtcttttt acttctctat aatattcctg cttttatcat tcattattat
     9241 agcctttatg gtggctattc tgttggtgct ggctttatta aaaagcttta tgagtctggt
     9301 ggtattaaga ttgtgaccaa gacctcaagc atgcttgggt caatgatggt tggctccatg
     9361 acagcttcaa atgtgaagtt taagaccatt ttaacagttg ctgcaaaggg agccaaggaa
     9421 gcagcctcta tccaaaatta tttggatcag ctctttattg gaattgtccc tcttttagta
     9481 accatgaccg ccttttggct tttgcgtaag aaggtgaaca ttaactggat tatgtttggc
     9541 attatgctat tgggtattgt tcttggtctt ttaggtattt gctaataatc tcctagcatc
     9601 aaggataggt aaggcaggga cttcttgctt tgcttatcct tttttgtagt gagggctgct
     9661 gaaatagcca cctgcttgct taaatggctt atggatttgt tagatagatt aagattttct
     9721 tagctttgag aaatgatttg gtataataga aggaaataag ggaaaaggct gcctatggaa
     9781 gaaagattta aaaagcgatt gcaggatgat atttcacatc atttttcaca ccaatcattg
     9841 attttgtcca ttttactgat tggactcttt ctcatttttt cattggcacc tcagcaaatt
     9901 gggctgtatc aagatttgaa ggctgttgaa catagctatc accagctgat tcggcaaaat
     9961 aaggcgcttt taacggagct caatcagcat attctgacca aatttgtgaa tcatcagctg
    10021 agctcttctg accttagcaa acaatattat cacctaagaa accgctcaca aagccaatca
    10081 gagctgctgg tttttgatgc taacagtcac atgctgtttg ctagtaatca gcatctggga
    10141 aatttttttc gcaatgctgt ctatatgaca gaagtcttaa aaaaagcaag gcaaaggagt
    10201 agcttcttga ggatcagtat ggataatgag gaggggcatt atttactgct gataaagcct
    10261 attaagatag atcatcaggt taagggctat tcgcttcttg tgatgaatgg taaggatttt
    10321 cttcagctat cacatcagat tgcttcagat tttgtgattg cagatcagtt tgacaatagc
    10381 tttgccttta ccaatcggac ctttatgacc tcaagtctga ataagcttga cagtcatttt
    10441 cttaagggct attttatctt tcacgagcat cgtgccttta tcctaagaaa ggtcgctctt
    10501 agtccttcta tcactcttta cagctaccgc cctttgattc cagtttctat tgcactcttg
    10561 ttttcattga tgtcctctgt catgatttat gctattttgt attggaagtc taaggctctg
    10621 gcgacgcaga ttgcttctag caattcagca gcgatcaatc agatgattct tgatatgcag
    10681 gccatctcaa ggcaggaaaa aaatgccatt gacctgcaaa gtcaagatga atttcaatac
    10741 ctgtcggttc agatcaatca gatgattagc cgattgcagg cacttcatca gaagacccta
    10801 gccttagaaa agcaaaatgt gagttttgaa aaacgcatgc tggaagccca atttaaccct
    10861 cattttctct ataatacact tgaaacaatt ttgattacaa gtcattatga cagtgacctc
    10921 acagaaaaaa ttgtccttca gctaaccagg ctgcttcgct atagcttaga cgaatcacag
    10981 gaggctgtgt gtctgggaga ggatttggct gtcttagaat cctatctgtt gattagccag
    11041 attaggtttg aagagctgcg ctacacgata gctgttgaac cagccctaga gaccctaagg
    11101 gttcccaaat tatttttatt gccattgatt gaaaatgcga tcaaatatgg tctgcgctat
    11161 cgccatgacc ttgtgattga gatcagcgtg agacagcttg ctgatggaat ttactttact
    11221 gtagcagata acggtcctgg aattagtcaa aaaaggcagg ccgatattaa agagctcttg
    11281 cattcagagg attcacatca tggcttggtc aattcttatc gtcgactcaa gcatcaattt
    11341 ataaaagttg aattgatctt ttgtcaaaga gatgagcgct ttttactaac ctatatggtt
    11401 aaggagtaac agatgtataa gctactaatt gttgaagatg agcatattat tcgcaaatgg
    11461 cttcgttatg cgattgatta tcatgcgctc aatatccttg ttatcggaga agctaaggac
    11521 ggtcagcagg gggctaagct gattgcagag gctaagccag atattgtttt gacagacatt
    11581 aacatgccga ttatgactgc ctttgagatg tttgaggcca caaaagagca gtcctatgct
    11641 aaaatcattt tgtctggcta tgctgatttc gctaatgcaa agtctgctat ccattatggt
    11701 gtgcttgagt ttttgaccaa gcccttggaa aggcaggcct tacatgattg cttgctaact
    11761 attatccaaa agctgcaaca gcagtctcaa gagcaggagc taagccagca gcaggattac
    11821 ctcaaactgc cacagcctaa tgaccaattg cctgatgttg tccaagaaat gctcagctgg
    11881 atccatgagc attaccagga taaaatcatg attggtcagt tggctcacga tctgggctat
    11941 agcgaaagtc acctctatca tttagctaaa aaatacctga aaatgacttt tagtgactat
    12001 atcaaccaat accgcctgaa tcgagcaatt caattgctga ttgctgagcc ggatgtgatg
    12061 gtttatcagc ttgcagaggc tgttggcatt tatgactacc gctattttga tcgtgtgttc
    12121 aaaaaatatt taggacaaac ggtcaaggat ttcagagaaa cggtattaca ccagagatca
    12181 gataggagtt cattgtgaca agaaaaaagc tgctattagc aatggcaata gtgatactag
    12241 gtgtgattgg ctctggcttg tatgctatct ggaggcatca agcaggacca gctcccagca
    12301 aaccaagaga attggttgtt ttgacaccca acagtcaaaa tatcctaaca ggtacgatcc
    12361 cagcctttga agaaaaatac ggcattaaaa tccgtctgat tcaaggaggc acaggccagc
    12421 tcattgatcg cttgcaaaag gacaaggacc agctccatgc agacatcttt tttgggggga
    12481 attacacaca atttgagagt cataaggagc tatttgagcc ttacctttca aagcatattg
    12541 gctttgtatt gcctgattac ctgctgcaaa gcgaggtcgc aaccccctat acgcttaatg
    12601 gaagtgttct cattgtgaat aatgaattgg caaaggacat ggttattacc agctatgagg
    12661 atttgctaaa gccagagcta aagggaaaga ttgcttttgc agaccccaac acctcctcta
    12721 gtgccttttc tcagctgacc aatattctct tagccaaggg gggctacact aaccccaagg
    12781 cttggagcta tatcaagcag ttgattcata gcatgaattc aatcaaatct gctagctcat
    12841 cagatgttta tcagtcagta gcagaaggaa agatgaccgt cggtcttacc tatgaggacc
    12901 cctgtgttaa ccttttaaag agtggtgcca acgtttctat tgtgtatcca aaggagggaa
    12961 cggttttttt accctcagca gttgccattg ttaagcaatc taaggccaag gctgatgcca
    13021 aattgtttat taattatatg ttgtctttag atgtgcagcg ggcctttggt caatcaacca
    13081 gtaataggcc aattcgaaag gacgctaagg ccagtcaaga catgaagcct ttagatgaca
    13141 ttatcacgct aaaggaagac tatgattata tcacaagaca taaaaaggat attttagaac
    13201 gatacaatca attgagaaag accactgact aaatggcttt gttatatgaa acagttcatg
    13261 ctgtgctgca cctgaatcgt tagctgcttt gtctagcttt ttgaggtcaa tctctgcttg
    13321 ggctgttttt tatgttacca taacccactg catttgttta gaaagtcaag cgagatctta
    13381 atagccagtt ataataggtc tttgagaggg agtctgagct tgcttgaggt ggcaagaaga
    13441 tctgttttga cgtcaaatgg ctgaattttt ggtaaaatga tagcatgaat gaactgataa
    13501 aacacaagct agagcttttg ccagatagtc ctggctgtta tttgcataag gataaggctg
    13561 gcactattat ttatgttggc aaggccaaaa atctgagaaa tcgcgtacgc tcttattttc
    13621 gaggaagcca tgataccaag acagagctgt tagtttctga aatagctgat tttgagttta
    13681 ttgtcacagg atcaaataca gaagcactct tattggaaat caatttgatt caagagaaca
    13741 tgcccaagta caatatcaag ctaaaggacg acaagtctta tccctttatc aagatcacta
    13801 acgagccatt tccaagacta ttaatcacac gtcagattaa aaaaaatgac ggcctgtatt
    13861 ttggtcccta cccagatgct tacactgcca ctgaggttaa aaagctgcta gaccgtattt
    13921 ttccctttaa aaaatgcaaa aaccctgtta acaaggtctg cttttactat catttagggc
    13981 aatgtcaggc tcacacgatt tgccatacag acaaggctta ttgggacagc ttggttgctg
    14041 atgtcaagca gtttttaaac ggtaaggacg acaagatcat tgatgatttg cgctccaaga
    14101 tgcttgaagc ttcgcacaat caagaatttg aacgggcagc tgaatatcgt gatttgattt
    14161 caggtattgc caccatgcga accaagcaaa gggtgatgag taaggacttg caggataggg
    14221 atatttttgg ctattttgtt gataagggct ggatgtgtgt gcaggtcttt tttgtccgtc
    14281 agggtaagct cattcagcga gatgtgaata tgtttcctta ttacaacgaa gctgaagagg
    14341 attttttgac ctatgtcggg caattttata gcgaccaacg gcatttgatc cctaaggagg
    14401 tctttattcc agagacgatt gatgagacct tggttgcagc cattgttcca gcaaggattg
    14461 tcaagccgca gcgaggggaa aaaaagcagc tggtcgcctt agcaactaag aatgctcggg
    14521 ttagccttca gcaaaaattt gatttgctgg aaaaggattt aagaaaaaca agtggtgcta
    14581 ttgagcatct tggtcagctg ttaggcattg aaaagcctgt tcgtattgag gcctttgaca
    14641 attcaaacat tcagggcaca agtccggtag ctgcgatggt ggtttttgtc gatgggaagc
    14701 ccagcaagaa ggactatcgc aaatttaaaa tcaaaacagt gattggtcca gatgattatg
    14761 cgagcatgag agaggtgatt tatcgtcgtt atagccgcgt gaagcatgaa gggctacagg
    14821 cacctgattt gattattgtt gatggtgggc agggtcaggt caaggctgct cgtgatgtga
    14881 ttgagcacca gctaggcctt agcattccag tagctggtct gcaaaaaaat gacaagcacc
    14941 agacccatga attgcttttt ggtaacccct tggcagtggt tgagctgccg agaaattcag
    15001 aagagttttt tctgctgcat cgtatacaag atgaggttca tcgctttgcc attacctttc
    15061 acaggcaggt caggagtaaa aatgcctttt catcaaagct agatcacatt gcaggcttag
    15121 ggccaaaacg caaacagcta ctactcaagc gatttaaaag catgactgct cttgaacagg
    15181 ctagtcttga agaaattcag cagctaggga ttccaaaaac agtcgctgag gcactgtttg
    15241 atcaccttac ctcaaaaagt gaggtctgaa ttggccttgt caggagctca agcagtctga
    15301 attttcttga caaaagtgaa aaaatagctg aaaccagttt caaaaaatga tagaatgata
    15361 ctacaacata aaagaattag ataggaagca tttgcagtga aatttctcga attaaacaaa
    15421 aaacgccatg ctattaaacg gtttaacgat aagcccgttg attataatga cttgcgaaca
    15481 gctattgagg ttgccactct ggcaccaagt gctaacaata ttcagccttg gaaatttgtc
    15541 attgttgagg aaaaaaaggc agagctggca aaggatctgc cgttggctaa taagactcag
    15601 gtagagcagg ctcagtatgt tattgccctg ttttctgata ccgacctcat tcagcgctct
    15661 cgtaagattg cccgcattgg ggtcaagtcc ttgcctgata acttgattgg ttattacatg
    15721 gagaccctgc cgccacgttt tgctaccttt actgagaccc aaaaaggcga atatctggcc
    15781 attaatgctg gcttggtggc gatgaatttg gtccttgcct taacggatca gaaaatggcc
    15841 tcaaatatta ttttaggctt taataaaaag ctaactaatg agattttaga tattgatcca
    15901 cgctttcgtc ctgaattatt gataactgtg gggtatagcg atgacaagcc agagcctagc
    15961 tatcgcctac cagtagacga aatcattgaa agacgctaag atacacaact actcgtccag
    16021 ctagcctata agtttttgga tttaggagga tagcgaggca acacataaag gagaaaaaga
    16081 tgacaacaat tgattttaaa gcagaggttg ataagcgcaa ggaagctatg ctagaggatc
    16141 tatcaaacct attaagcatt aattccgagc gagacgatgc taaggcagat gccaagcacc
    16201 catttggtcc tggtccggtt aaggccttgg agttctttct tgccatggca gagcgtgatg
    16261 gttaccaaac gcgtaatatt gataactatg ctggtgattt tgaatttggt cagggagatg
    16321 aggttttagg gatttttgcc catttagacg tggtacctgc tggtagtggc tgggagacag
    16381 acccttataa gccggtgatt aaggataatc gtatctatgc gcgtggttca tctgatgata
    16441 aggggccaac catggcttgc tattatgccc tgaaaatcat caaggaatta ggcttgccag
    16501 tttctaaaag ggttcgcttc attgttggga ctgatgagga gtcaggctgg ggtgatatgg
    16561 actattattt tgctcacaat ggcttgaaga accctgattt tggtttttca ccagatgctg
    16621 aatttcccat tatcaatggt gagaaaggaa acattacaga ataccttcat tttgttggtc
    16681 aaaatgctgg agcttttgtc cttcatcgct tccaaggcgg tttacgtgaa aatatggttc
    16741 ctgaatcagc gacagctctg atcagctcac cgcatgagct taatgttatc gaagcttctt
    16801 tggagcaatt cttatctgag cacgcagtga caggatctgt caaagaggct gatgggctat
    16861 tggaagtgac cattattggg aaatctgctc atggctctac accagaggct ggtgttaacg
    16921 gtgcaaccct gctggctaaa ttcttaaatc aatttagctt tgatggcgca gccaaggctt
    16981 atttgcatat tgcaggtgag gtgcttcatg aggatttcac agcagaaaag cttggcttgg
    17041 cttatacaga tgacaaaatg ggtgccctta gcatgaatgc aggtgtcttt agctttgcta
    17101 aggattcaga tgacaatacc attgccttga atttccgtta tccaaaggga accaatgcag
    17161 cagtgctaaa ggcagggctt gagcaattac caggcttgac taaggttacc ttatctgagc
    17221 atgaacacac ccctcactat gtgccaatgg acgatgagct ggtctcaacc ctcctatccg
    17281 tctatgaaaa gcaaacagga ctcaagggct acgagcaggt tatcggtggt ggcacctttg
    17341 gacgcttgct tgagcgtggt gttgcctttg gtgcgatgtt cccaggtgat gaaaacacaa
    17401 tgcatcaggc caatgaatac atgccattag acaatattta ccgatcagct gccatttacg
    17461 ccgaagctat ttatgaattg atcaaataag agattgaaca agctctctgt ctaagatgag
    17521 ccttgctaat attaacgaat aaaagcctta tgaagttagt cgtttaatga gacttcataa
    17581 ggctttttgt ttggcgtcaa gccattattt acaaagagaa atgccacagt ggatcatctt
    17641 ttgaaaagtc cttgtaaaaa cagacgtaaa actagtttta gaggagacat tgataggcag
    17701 tcatgcttat caagagatct tgtctagcag ttatggcaaa aagatcagtg aactattatt
    17761 ttccaaggca gaactgactg aacaattgag taattaattc atcaggtgcg gcatcgcctg
    17821 tgatttctcc taggatttcc caagctctgg tcaaatcaat ctgtaagaga tcaaccggca
    17881 ttcctaaagc aagtccttca ttgacagcct ctaagctttg tactgcctgc tcaatcaagg
    17941 aaatatgacg agcattggat aggtaagtcg catcttgctc tattagccca gtatgatcaa
    18001 agaaaatctg attgatccgg tcttcgatca ggtcaatgtt ttggttttgc aaaactgata
    18061 ttgggatcgc ctcttctgga agctggtctt tttcaatgac ctgctccaga tcggttttat
    18121 tgaggagaat aatgcgattg ctatcctgac taagggctag cagagccttg tcctgttcgg
    18181 tcagcttttc cgaagcattg agaactaaaa ggaccagatc agcctcctgt agggcttttt
    18241 tagaccgctc aacaccaatt tgctctacta aatcatctgt ttctctaatt ccagcagtat
    18301 caactagctt tagaggaatt cccttgatat tgacatattc ttcaatgaca tcacgagttg
    18361 ttcctgcaat atcagtgaca atggccttat cctcacgtaa caaggtattg agcagactag
    18421 actttcctac attcggtcgg ccgataatag ctgttgacaa gccctcacgt aggatcttcc
    18481 cgcgcttggc agtacgtagg agctgctcta aaagtgtttg aaattctcgc gttttgtcac
    18541 gcaaaagagc agtggtcatt tcttcgacat catcatattc ggggtagtcg atattaacct
    18601 caacctgggc taaggtattt aggatttctt gacgtgtgtc gctgatgagc tgtgataggg
    18661 agccgtctag ctgcttgata gcaatagaca tggccttatc agtctttgca cgaatcagat
    18721 ccatgactgc ctcagcctgt gttaaatcaa tacggccatt taaaaaagca cgctttgtaa
    18781 attcgccggg ctctgccatt cgagctccct gtttaatgag gagctgtaaa atgtcatttg
    18841 tcaccgcaat accgccatgg gtattgattt caatcacgtc ctctctggta aaggtttttg
    18901 gcgccagcat gactgatacc atgacctcat caatcacttc acctgtgctt ggcttgataa
    18961 tatgaccata gttaagggta tgtgaggcga ctgttgttag atcttttcct ttaaagatcg
    19021 atttagcaat gtccagagcc ttggtaccag acaagcgaac aatgccaata gctccttcac
    19081 ctaacggagt tgaaatggct gcaattgtat caaattcttt agttatactc atgccttcta
    19141 ttgtagaaca agtcagcata gaaagcaagg tattgcatta gctgctcgtt gtcgtcattc
    19201 ttgtctagtg gcaaagcctc aaaagcagtt gtaaacagct aaagctatga ttaaaaagcc
    19261 ttgtatggta agtacaggat aaagccaaaa agctgatgag ttttagataa acatacaggc
    19321 tcgaaaagcc ctattaaacc gacagcaaca atcctcacac agtatagttg acttaactac
    19381 ctgatgtcat ttctggctgt ttttataatg acaatggcaa tatcggttat tttgactatg
    19441 ctgggtgctt gtatcctagt ggactgactg acaatcaggg cttctttttc aaccacgaaa
    19501 acattaaaaa agtctggttt ggaggctata ttgacgatag tgaaagagaa gctcaagact
    19561 tttttaaaaa agaggcaggc tatattaaat atcctaaact tagtatagat aatagcacta
    19621 gatagcatta atttaagtat ataacgttat gattatggtt ggattagttc attatacact
    19681 agcaataagg tagattattt tgttataata aaatatatac aattattaga gagttagaaa
    19741 gagttatatg gtagtattac aaaataatag tagcacagct agtgagcgag cgacagcttt
    19801 ggcaagagga gtccaggccc tctctagtgc tggtgcggtg agcaaagata tgaagacgac
    19861 cgttactgga aatcgtagtg atgccagctc tgccattgat ttatcgcaca acgtttcagc
    19921 gcaggtagtt gggatcatcg cttctatgtc gcaacacatt cagagtgtct ctgcctcttt
    19981 tcaagcgatg gatcttcagc ttggaaaaga gttagggcgt ttagaaaaca ggcggaggtt
    20041 tagtctcaat gacccaaaat gagctcatgt accagaagga gagattggat aaacgcttgg
    20101 aaaccatagc ccaagagctt aagcgtaatg aacagcgctt tgaagactat gaggaactat
    20161 ctaacctagc ggcacaactg ttaacagcag ctgcaaccac ctttcgttca tcatcagata
    20221 gtcatctctt tgaaggggct ttggcagaag aatgttattt gaaaaggaaa acacaagcgt
    20281 ccttggaaca aagtcatgag gagctcttag gagagcagcg tcgtttgtac caagaagagg
    20341 aagccctcac ccgacaatta aagctagtca aaggaaagga gagagctaat gagcattgac
    20401 atgtatctgg ggtcatcgga ccagcaagct agtagcgttg gtaaggtctt gcagcagcgg
    20461 ataacagctt ataagtcttt gcaaagagct ttggagcaat tggtgtcttc tagtcctgac
    20521 ttatcagggc atacctatgc ttctgctaaa aggtacagcg agcaggtatt gatccctttg
    20581 atgaggggct gtatcctgct agatgaagcc atcaaggaag cctgtgcagc atttcctaat
    20641 gactaccgtc gtcaggttga tagtgtggat ttgaaggaga gtgagctggt ggatcagatc
    20701 agccgctcag accgcatcat aggtcgttac gttgagttga ttgatctgga gtatcggcag
    20761 gagctgccga attactctta tattactaat ctcaagagcg gagcgagtaa ccagcgtcaa
    20821 gtcaagagaa aattagaaga gaagctcctt aagctgcgag agtttgatag caattcccgt
    20881 cacctctttt cgtctatcgc agccttagcc gaggcagtca atataggtat cagacaaacc
    20941 aagacctctt ggaatgggac aagtcagacg ttcactcttc ccagggctct tgacttagag
    21001 tggaccaagg tagtagaaaa gaggtggacg caaagggagg aaaaagcctc gaagctgaag
    21061 ctacagcagg cagcagaaaa actttcgaga gaaaccggga ttaagtacga agatgcctat
    21121 cgttttgtga tggacggtgt tctgtcagat gaaaataaga acaaaatcaa gagtgtaaag
    21181 aaactagtta agtatacaaa gggtgggctg tatatcgttt cctcaggaag gtattattgg
    21241 aaacattcag gtaaacatta ttggaaaaat acaccaaaca aaacatggaa tatttggaaa
    21301 gcatctaaaa acgatcccaa ttttgacaaa ggagggatca aaggtaaaca tttttctaaa
    21361 aaaggagccc gttacacaga cttacctggt atcaagcaat tgaagaagag tgaaacagta
    21421 caatccctca tttcaaaaat ttcaaaagat aatcaaggga agctcaccaa agttggtaaa
    21481 gggttaaaga aagttgataa agagctaagc aacatatcgt caaaactcaa gtcatatgag
    21541 catggacgcc taaatagaga cttgaaaatg atgaaggaga ataacctggg taaaagtctc
    21601 ggtaagtttg ggaaagttgg aaaagctgca agcaaggtgc tcaagtttgc aggaaaaggt
    21661 ctcaaagttg cgggttgggt aggtgctgct ataaatgtta aggactcggt tgaaacttac
    21721 aagaaaaaag gctatagcaa tgagcaaact gctgctttaa cagcccgtaa ggtagctgtt
    21781 gatactgcaa caactgttgt cggaagcaat attgggcgtg taacaggtgc agttattggt
    21841 caagcagtta tacctattcc aggtgtaggt gctgctatcg gttctgttgc aggaagtatt
    21901 ttaggagcta tggcaggtag ttggattggt agtacaatta atgacaattt agataagaac
    21961 gtaaaaccta aacaatcagg aaggagttta gcatggtaat gttaatgaga acactgttat
    22021 ttccagttga taacggactt gattcaggat tgactggtga tggttatgca gctgagtatg
    22081 atttgtggac tggaaaggtc acgtggcgac aacttggtga tggaaaaata aaaaggcaac
    22141 aaaaggtagc agctataatt aatctcattg cagctgcaat atctccactt gtcatcatgt
    22201 ctatcatttt tacggcaaaa agtctgaagc tttttgatgt agatactagt acaacaattt
    22261 atcgatatgc tcctctgatg gtaggcttgg tctttttctt ctcgtttgaa ttattgatgc
    22321 tggctattag acgtctgtat ccattagcca aagaggagcc aagtttaaag cgtcaacatg
    22381 ggtattttaa gaccatgtat gacaatacta tacgtgagaa tgatggtgtt tttaataatt
    22441 tatcagtacc ttttataggg ctttatgtag ctttcttgat tgccttttcg gttattccaa
    22501 ttttttactc tcaatatctg cagcaaaatt ctttttggtc ctatttagga aatttagtag
    22561 gaagtagcat tcttatttcc ttagtcccca attttttatg gaatgtctta gtgaaacaat
    22621 tgatttacat caagcttatt cgcaaaacga aagaaaaaat cttaaagaat gaaacctaaa
    22681 caatcaggaa ggagtttagc atggtaatgt taatgagaac cttgttattt cccatagata
    22741 atggtatgga taataactta attggagacg gcttatcagc tgagtatgac ctatggactg
    22801 gaaaagttac gtggcgtcag cccagtgatg ataagattag aacccaacaa aaggtagcat
    22861 ttgtacttaa tcttatagct ggtagtttat ctccattagc tatattttta tttgttatta
    22921 ttgttagacg cttaggcgtt tttagtggcg atactaattc aatgattttc aagtgggcac
    22981 cgctaatagt tggatttatc ctttttatat cgtttgaatt attgatgttg gcgcttagaa
    23041 gtagatatac gatattagag aaagagcccg atttagatcg tcaactatac tattatcgta
    23101 caatgtatga taatactata catgacaatt caggtgtttt taacaattta tcagtacctt
    23161 atgtaggtct atacattact ttatttctaa tttttttaat cattccactt tgttatcatt
    23221 tttacttgca cccatcttca tttggggatt atctcgctgc attatctgta acaagtttgt
    23281 tgatttcctt atttcccaat tttttatgga atggtgtctt gaagcacgtt atatatgtca
    23341 aacttattcg ccaaacaaaa gaaagaattt taaagaatga aacctaaaca atcaggaagg
    23401 agcttagcat ggtaatgtta atgagaacgc tgttattccc agttgataat ggcatgggaa
    23461 cgggcttgac cggtgatggt tatgcggctg agtatgatct atggactgga aaggtcacgt
    23521 ggcgacaagc caccaaacaa acaattgaaa agcaacaagc actaacgtct aaccttttga
    23581 ttattgcctc atgcttatca ccagttactg ttgcaggaat gatactgttg agtagaagtt
    23641 tccctatttt cgaggaagac ttatcagaga aaattgatac ttatgctcca attattcttg
    23701 gtgttgtgtt atttcttgct tttgagacgt taatgcttgc tatcagaggt cgtgatccat
    23761 tagcggagaa ggaaccagat ttaaagcggc agcatgacta ttttgaaaag atgtttgatt
    23821 ttgctattcg tagaaatttg tcgtcagata atctaaaaac tccttatata gctacttatt
    23881 ttgcttttgg tatttcttta ctctgtattc catttagcta ttatgtttat ctgaatccgg
    23941 agcaattccc taatttggat tatggtcatt tatcaatcct gcttgtaaca agtattctta
    24001 tttccctagt tcccaacttt ttatggaatg ttctattaaa gcacattatc tatatcaagc
    24061 ttattcgcaa aacgaaagga caataaaaca ttatgaacaa accagaacac attttaccga
    24121 ttggtactat agtgctgacg gagacaggag aaattccttt gatgattgtg agtcgtgcct
    24181 ctctttttga tgataatgga gaaatcggct attttgatta tgctgcagtt ccttatccag
    24241 aaggcatagg aaatgataat gagtaccttt tcttcaacca tgaggatatt gctgatgtca
    24301 tctattttgg gtatgtcaat tccaatgaac agctttttgc agaagcctac gatgatttgg
    24361 tgaaaacatc aggttatcgt aaattaagct tagatcacca tcaatagaaa aaggacatga
    24421 agattatcta gaaaaagaaa agaactaatg agcattgaca tgtatctggg gtcatcgaac
    24481 cagcaggcta atgatgtatg gccaatattt tgagaggatc ggcctgctcc tcttttttgt
    24541 atgttcaaag ctataaaaag cttacttttt gaggtataaa gcttcgacaa tcaagagtat
    24601 ttgctctggt ggctttaatg atcttgctta tagcttctgg tcagattgtt ttagcctgct
    24661 tgtgctgtct gatccagatt tgactgaggc tttgatgaca gtcgtgaagg cgggtttaag
    24721 aatggcatgt ctaatgtcaa tttacaatag agaaggaaaa ttgatcaaac agtgtgagat
    24781 attattaaca agtttgcgct ttcatggtat aataaagtgc taggaagcat tttattataa
    24841 gataaggggg aatcatggaa gcactgaaaa agattgccgg tgtgactgct gcgcaatatg
    24901 taacagatgg aatgaccatt ggattaggaa caggatcaac agcttattac tttgttgaag
    24961 aaattggtcg tcgcatcaag gaagagggac tacaggttgt tggtgtgaca acctcaagtg
    25021 taacaaccaa gcaagcagag ggcctaggta ttcccttaac atcaattgat gatattgact
    25081 gcattgacct gactgttgat ggtgctgatg aggtggataa ggcctttaac ggtattaagg
    25141 gtggtggagc agctctattg atggagaaaa ttgttgcaac accaaccaag gaatacatct
    25201 gggttgttga tgaatcaaag ctggtggatc atttaggtgc tttcaagctc cctgttgagg
    25261 tcgttcaata cggtgctgat aggctatttc gagtctttga aagggctggc tataagccct
    25321 cttttcgcat gaagggggat aagcgtctca taacggatat gcagaacttt atcattgatc
    25381 ttaaccttgg ctgtatcgaa aatccttgtg agtttgggcg tctgctggat caaactgttg
    25441 gtgttgtcga gcatggcctt ttcaatggta tggttgataa ggtcattgtt gctggtcagg
    25501 ctggtgtaac ggtccttgaa gctaatcagt caacctaatt cctagctcaa tcatgtttta
    25561 cattatttta taggttttgg ggagccaacc gtaacctccc ctagattgga gacttatgtc
    25621 aaaatttaat cgtattcact tagtcgttct agattctgtt ggtattggtg cagcaccaga
    25681 tgccgacaaa ttctttaatg ctggtgtagc tgatacagat tctgacaccc tcggtcatat
    25741 ttcagagaca gctggtctgg ctgttccaaa tatggcaaaa attggacttg gtcatattcc
    25801 tcgtcctgtc cccctaaaga cagttccagc tgaggctgat cctactggct atgtcaccaa
    25861 attagaagag gtatctcttg gtaaggatac catgacaggt cactgggaaa ttatgggctt
    25921 aaacattact gagccatttg ataccttctg ggatggcttt ccagaggaga ttatccaaaa
    25981 aatcgaagct ttttcaggcc gtaaggtcat tcgtgaagcc aataagcctt actcagggac
    26041 aaaggtgatt gatgattttg gtccccgtca aatggaaact ggtgagctga ttgtttatac
    26101 ctctgccgac cctgtattgc aaattgcagc acatgaggag gtgattcctg ttgaggagct
    26161 ttaccggatt tgtgagtatg cgcgttccat tacccttgag cgtcctgctc ttttaggtcg
    26221 tattattgcc cgtccgtata taggagagcc aggcagcttc actcgcacag ctaatcgtcg
    26281 tgattatgca gtctcaccgt tccaagacac tgtcttaaat aagctggctg acgctgggat
    26341 ttctacttat gctgttggga aaatcaatga catctttaat ggctcaggga ttaccaacga
    26401 tatggggcac aataagtcta acagtcatgg gattgatacc ctgatcaaaa gcttgcagtt
    26461 gccagcattt acaaaaggtc tttcttttac taacttggtt gattttgatg ctagctttgg
    26521 tcaccgtcgt gatccagagg gctatcgtga ctgtttgcat gaatttgatc gtcgcctgcc
    26581 agagatcatt gccaacatga aggacgatga tctgctcttg attacagctg atcatggcaa
    26641 tgacccaacc tatgctggaa ctgaccacac acgtgagtat attccattgc ttgcttactc
    26701 agcctcctgc actggagcag gtgtgattcc acagggacat tttgctgata tttcagcgac
    26761 tattgccgaa aacttcggtg tggacactgc tatgattgga acatcattct tagctgactt
    26821 ggtataggag taagcaaata tcatttgata ggccaaggag cttggcgtat caaattgaaa
    26881 accagcgctg tggttaggtc tattaatagg cttgtggcag gttgtctagt tctgatgatc
    26941 ggtgtgatat tagttgattt attggacttt gctacagcaa aaagctcaag agaagtatgc
    27001 tttatagtaa aaaataaata agataaaggg agaaataaga tgacattact tgaaaaaatt
    27061 cgtgaaacac aggctttcct agaaagcaag ggcattgata agcctgaatt tggtctcatt
    27121 ttaggctctg gtctaggtga gcttgccaat gaggttgagc aggcgattgt gattgattat
    27181 gctgatattc caaactgggg caaatcaaca gttgttggtc atgctggaaa attagtttat
    27241 ggtgagctgg ctggtcgtaa agtattggca cttcaagggc gctttcattt ctatgaaggt
    27301 aatccaatgg aggttgtgac cttcccggta cgtgtgatga aggctctggg ctgccatagc
    27361 ttgctggtga caaatgcagc aggcggtatc ggctatggtc ctgggacgct tatgctaatc
    27421 aatgaccata ttaatatgac aggaacaaac ccgctcattg gtgaaaacct agatgaattt
    27481 ggcccacgct tcccagatat gtctgatgcc tatacagcag cttatcgtga gacagctcgc
    27541 tcagtagcag aaaaactagg cttagacctg caagagggtg tttaccttgg ctgttcagga
    27601 ccaacctatg aaacaccagc tgagattcgt gcctttaagg ttatgggagc agatgctgtt
    27661 ggtatgtcaa ctgttccaga ggttattatc gctgcccact caggcttgaa ggtgcttgga
    27721 atttcagcga ttacaaactt tgcagcgggc ttccaatcag agcttaacca tgaagaggtt
    27781 gtagaggtaa ctgagcgtat caaggaaaac tttaaaggct tggttaaggc tattttggca
    27841 gagctttaag gcttgctctt agactagcag taaccatgag cgactgctag tactttgatc
    27901 gataagacga ggaaaaataa ggattgggac attagagtga tgactgatat ggaacatacg
    27961 ataagtattc ttttagaagt ttatgcttat agtcatgcct acaaaattgc aagaactctg
    28021 cctgattttt cccccaaggt actttatttg cttgagcttt taaaggaaag aagagagctt
    28081 aacgttgctt atgcctttca acatagggcg gaaaataggc ttattgagga tagacatcag
    28141 gttaagcttt tgttaaatga agctcaagag gaggagcaga ctgcaaatta cctgcttgat
    28201 ttggcagcta aggtcaaaaa cggtgagatt attgattttg taaggtcagt atcgcctgtc
    28261 ttgtatcgtc tctttttgcg gctgcttgag caggctgtcc cagatgttca aagctatatt
    28321 attgatacca agaatgatca atatgacact tggaatttta aggcgatgga aaaagccgat
    28381 aatgacctct ttaggagcta tctggcacaa agacagccac gtcatgtgac gacacgcagc
    28441 ttggctgatt tacttgtttt atcagagctt ccagctgata ttaaaagact agtggtagtc
    28501 ttaaggcagt ttgaaaaatc agtccgcaat cccctagcac atttgatcaa accctttgat
    28561 gaggaggagc tatatcggac aactcatttt tcctctcaag cctttctaga tggtttgatt
    28621 cgcttagcag ttttttctgg tgttaactat atcaaagagc ccttctattt tgatgtcgtt
    28681 aatgctgtca ttgaaaagga gctgttagac agcgccaagc cttagctatt tgaaagatta
    28741 gcaataataa aaaacctgaa cgatctgaac gaggcttctc taagctagct atgactagtc
    28801 agcttagagc cttagaacag gtctttcagg ttttttatgt ttagctagtg tggttaatta
    28861 atgattgaag ctaatttctt ctagcaggta gtcaataaat cgctctccca tttttgagag
    28921 gttagccttt tcgtgcttga taaagacaat ctcaatcaca tcagggacat ctaagggaat
    28981 agcgacaatc tggtctccat ttagatttgt gtttaaaata ccgctggcaa cggtgtagcc
    29041 atttaagcca atcatgagat taaatagggt agctcggtca ctcaccacaa tagacttact
    29101 gtgagggata tgtgccatca tctcctctga gaaataaaag gaattgtgaa tcccctgatc
    29161 atagcttaga taaggaaaat caaggagatc atcaatggtt aagctggttt tatttgccag
    29221 aggattggac ttgctgataa agatatgcgg tgtggtttta aatagggtgg aaacggtcaa
    29281 atgattttcc tcaaacagct tggtaaggac gtctcggttg tagtcattga taaacaaaac
    29341 gccgatttct gagcgaaaat ttttcacatc gtcaatgatt tcccaggttc ttgtttctcg
    29401 caagaaaagc tcgtactggg tcatatcagc ccgctttaat aaagagacaa aagcattgac
    29461 aacaaaggcg taatgctgag aggaaacact aaagagctca cgactagtat tgtgattttt
    29521 atagcgatcc tctagcagtg ctgtttgttc aataatttgt ctggcataag atagaaactc
    29581 aaccccgtcc ttggttaagg taatgccctt gggattacga atgaaaatag taatgcccat
    29641 ctcctgctct aattccttga cagcattaga cagactgggc tgcgtgataa ataattgctt
    29701 agcggcttcg ttcatggaac cgcattcaac aatctttata atgtattgta gttgttggat
    29761 tctcatactg acagtctatc ttaaatagta caaagaatca agtgccttta ttagagctta
    29821 agacaaggtt tcacaagcgg tagcctagct tgtgcggtga agctagcttg atgctagtgt
    29881 tgtacccagg taaaaaagag ctggcaaata ggcagtttta tcgcttttta ccgcttattt
    29941 ttggcatgcc tgtgttttga taaacggctg gtcttgatcg gtaaaaagta atcgtgataa
    30001 tgtcagataa tacctatttt tccattgctc ttttaatttt cttgtgttat attaataata
    30061 ttgatatatt taatgttttg agataaaggg tggtgatggt gtaatatgac tggacaaagt
    30121 agtcatcagg tattaattca aaagctgttg gtcagcactc actatttgac attatttaga
    30181 gatgagctga agctagttga gaggacacca tctattttgg gaagtgagtt tcctgtctct
    30241 cttgttcaaa cggaattagg tgatattatc accttggtgg ataccttaaa taagcagcag
    30301 cgcttgattg agtcgacctt ttggtatgag gagtcagcct ttaagctcat gaacaaggcc
    30361 ttagatattg ttgataattg gataaagggg atagatggct taattaagct ctgccagtcc
    30421 aaggaggtct ttcaggccat tgttggtgat aaaagaacac gtgtttttgg tgttttgatt
    30481 gatgtttttt cttccctaaa aattagcacc atgtcattga aggaatttgc agctccggct
    30541 gctctttgcc attagattaa gctgggctaa gcttggatag tggctggtta agcctgcaag
    30601 ttgcccctct catgacaagt ctaggcttta tttagggtga gcagtgtgcc aagggtgtat
    30661 taagtgctgg ttgctttgaa gcttcgcctt gctaggttag ctgtgagtga tgtcacgata
    30721 actgcgcgaa acagttattt ctgaattata atacaggtta aagtaggtac ttttaatgtt
    30781 tttcctattg taaaatctat acaaaatagg atatattttt gaaatagctg aacattaacg
    30841 tacagcaagc tttattttct tgctaaaaat cttttttata cctttgtcgt gtgagtaatg
    30901 tcaaaaccct ttgacaaggg ctgtcaaaaa agctataatg attgagataa gttaccttta
    30961 agtgagtcca gagaggcgag caaggtacac aggataagat gagagggttt gctctcttga
    31021 ttttcgtgta gcctcgcttc tttggaagtg aggcttttat ggtgtgactt tcagttggtc
    31081 tcgtggtaat gattcataag accaataaac cgctcgttag acgggtgggc atgatttgtt
    31141 tgggagtacc ccaagctgca tagaaaggat aggttatgcg agaagaacgc cctattattg
    31201 ccttagattt tccttccttt gaggaggtca agtcatttct gtcgctgttt ccagctgatg
    31261 agaggctata cgttaagatt ggtatggaac tgtattatgc tgaaggacca gatattgtcc
    31321 gttatgtcaa gtccttaggt cacagtgttt ttctggattt gaagctgcat gatattccaa
    31381 atacagtcaa atcaacgatg gcagtcctat caaggcttgg tatagacatg acgactgtgc
    31441 aggctgctgg aggtgtagag atgcttagag cagcgcgtga gggcttgggg cagggtccga
    31501 ttctcattgc ggtgacacag ctaacatcaa ctagcgaaga gcaaatgcgt gaggatcaaa
    31561 acattcaatc cacgctgtta gcatctgtgc ttcactatgc caagcgtacc gctcaggcta
    31621 agctagatgg cgtggtttgc tcagcccatg aggtcaaggc cattaagtca gaagtaccag
    31681 caggctttgt gtgtttgaca cctgggattc gcccgacagg tgctgacatc ggagatcaaa
    31741 agcgggtgat gacacctcat caagctagag ctatcggaag tgactatatt gttcttggtc
    31801 gtccgatcac tcaggctaca gaccctgtca aggcttatca ccagattaag gcagagtgga
    31861 accgttagca gcaggatcat catgacacat atagctggac tatgacacca aggaaaagag
    31921 gagaaaaatg acactagcag cacaaattgc aacagattta cttgagatta aggccgttta
    31981 cctaagacca aaggagccct ttacttgggc gtcaggcatt acatcaccga tttatacgga
    32041 caatcggatc accctttctt atccaaaaac cagaagcttg attgaaaatg gctttgtgga
    32101 gacgattaag gcagtatttc cagaggttga ggtgattgct ggcacagcaa ctgctggtat
    32161 tccacatggt gctatcgttg cagataagat ggacctgcct tttgcctata tccgcagcaa
    32221 gccaaaggat catggagcag gcaaccaaat agaagggcat gtgcgctgcg ggcaaaaaat
    32281 ggtgattatc gaggatttga tttcaacagg tggatcagtt ctggaggcgg cagcggcagc
    32341 tagtcgcgaa ggtgctgatg tactaggagt ggtggcaatt tttacctatg aattgccagt
    32401 agcaagcatc aattttgaaa aggcagggct ttccttggtg accttgtcta attattcaga
    32461 cctcattaag gtcgctaagg ccaagggcta tattgatgct gatggcttgg ccctgttaaa
    32521 aagatttaag gaggatcaaa agcattggca gcatgagagt taaacagtgc tgaaaagctg
    32581 ctgacatgct gactatgtct taaggagaga aaaaatgact tacaaagatt tacttgagat
    32641 aggtgagacc agttattatc agacggatcg cttgacttac tacaaaaatc ctgtggtatc
    32701 tgagcgctat tttgataatt accttagcta tcgtagcatg ccttctttgg ctgatttgaa
    32761 aaaggacttg gcctatgtgg caaaagagca gcaggattat cctagtcact acgcctttct
    32821 cttttttgct gaaaatgaag agctaagtac agacatgcga gcttatttga cagatcatca
    32881 ctttagcctt gaaaagcacc tgatctttac caatgagctg gcaaagcttc acctaaagga
    32941 gcgtgatata tcaccagtca ctattgaaca gctctcagaa acaagctttt ctgcctatct
    33001 ggcttacaaa tatcaggcta atttggctta tggtgaaacc tatgccaatc aatgcaaggc
    33061 tgataatgaa gccaatctat tgacaaacgg ctcaaccatt tatttagcca tcaaggaagg
    33121 gaagattatc ggagatatta cggcttggga atgtggcgac tatattgaaa tggacgattt
    33181 cagtgtagat gaggcctatc gtggtcgtgg tatcggtaca gccttacagc gtaaggccag
    33241 tcaaggctat aagaaggtca ttctcatctc agaagaagct aatcgcgcca tgtatgagca
    33301 ccaaggctat caggaggttg cttactactg gacagcgcta aaaacatcga ctagataagt
    33361 gataaagaaa cagattatag gattgaaggt gtaggctctt atgagtatga ctcttcaatc
    33421 ctttttttct gagcgcattt gctaatcata cctaatgaat aagtcgtagc ctgtctagtg
    33481 gctcatttta atggcgtctt gctctgtttt atgattaaat atagagaaaa agctattgtt
    33541 agggcatgct tgttggtcta gcaaggctga tggatgatag gatagggaat tgatgatttt
    33601 taaagatgca acagaaatgg cgcaggctgt tcgagaaggt agggtgagcc cctcagcctt
    33661 agtgagagac acaattaaaa aggctcaagc actcaatcct gagttgaatg ctattacctc
    33721 agagcgtttt tcagaagctc ttgctgaggc agcagcaagg gatttttctg gaaagccatt
    33781 tgctggtgtg cctatttttc taaaggattt agggcaggag caggagggcc aattggccac
    33841 tgcaggatca gtgttattta aggattatcg tgcctcaaaa acggattatg ttgtgcagcg
    33901 actagaggag ctgggcttta ttattttagg aagaagcaat acacctgaat ttggctttaa
    33961 aaatattagt gatagtcgct tacatggtcc ggtaaatctg ccacaggaca agagccgtaa
    34021 tgctggtggt tcatcaggtg gggcagcagc tcttgtgtcc tcaggaatca ccttgctggc
    34081 tcctgctagt gacggaggag gatccattcg gattcctgcc tcctttaatg gcttgatcgg
    34141 tttaaagcca agcagaggaa gagtgcctgt ggggccaggc tcttatcgtg gctggcaggg
    34201 ggcgtctgtt cattttgctc taacgaggtc tattcgagac acaagtcgtc ttctttatca
    34261 cttgcaggtt tatcaggtag aaagcccttt tccattagtg ccattaacca aagaagagct
    34321 ttttcaccct ttagacagac ccttaaggat tgctctttat gatcacatga tagatggaac
    34381 taccgcctct atagatgctc agacagcttt aaccgaggcc tgtcattttc taaaagagat
    34441 ggggcatgag gttgtgcgat tagataagct tcctctagat ataccaaagg ttatgaggga
    34501 ttactacctg atgactagtg ttgagacagc tgctatgttt gctgatagcc aagaagccct
    34561 tggtcgtcag gtgaccaaag cagatatgga ggtcatgacc tgggctatct accaagcggg
    34621 taaggatatt cttgcttcgg tctattctca ggcgctgcag cgctgggacc attatagtgc
    34681 tgaaatggca agctttcatg agcagtatga tcttttgctg acctttaccg ccaatacgcc
    34741 tgctccaaag catggacagt tccagccaag caaggagcta atagataagc tggctaaggc
    34801 ggaatgctac ccctccagtc agcgcctagc gctagtagaa gccatgtttg agcagagctt
    34861 gttcataacc ccttacacag ctttggcaaa tctgacaggc caaccagctc ttagtttacc
    34921 aacctatgaa acgtctgctg gattgccgat gggcattcaa ttgatagctg ctaaagggcg
    34981 agaagactta ttgctgggaa tagctagaca gtttgaacgg gctggattgt taaagctacc
    35041 tggttaaata ttataaaaca gagctaatct attataggtt agcttttttg ttaaatcgag
    35101 catatctagt ctcttataag attagtcaat gctatactgt cattaataat gaaaaaggag
    35161 ttcttgatga aaaaaggagt tgctttactt tctgttagct tggcgagctt gctgttagcc
    35221 gcctgtgggt cacagccatc agctcaaaaa acaagctggg aaaagattaa agataaaggt
    35281 gttttaaagg ttgctacgcc tgcgacctac cagccaacat cgtactataa tgatgccaat
    35341 gaattggtcg gctatgaggt tgacctgatg aaggaaattg ggaaacgcct tgatcttaag
    35401 gtgaagttca ttgaaacagg ctatgatcag gcttttactt cggttgatag cggtcgtgtt
    35461 gatgtttctc tcaataattt tgacattaca gccaagcggc aaaaaaaata caacatctca
    35521 acgccttata agtatggtgt tgggggaatg attgttcgtg ctgatggcag ctcaggcata
    35581 agcaaggctg acctaagcga ttggaaaggg aaaaaagcag ctggcgcctc tggtacagaa
    35641 tacatgaagg ttgccaagaa gcaaggtgct gaattagtca cttatgataa tgtgacgggt
    35701 gatgtttacc tgaacgatgt tgctaatggc agaacagact ttattcccaa tgattatcct
    35761 gcacaaaagc tttttgtgga ttacatgaag tctcaaaatc ctaacctcaa tgtcaaaatg
    35821 agtgatgtgc tgtataatcc gacagcacag ggcattatca tgagtaaaaa agatgacacc
    35881 cttaagaaaa agattgatgc ggtcatcaaa gacatgaaac aagatggcag cttgaaaacc
    35941 atttcaaaga catactatgc tggtcaggat ttgacagttc cttttggtaa ggacaagaaa
    36001 attccagtca ttgatgccag tgatgtggac tagtgcctta gacaaaggag ctctaaagcg
    36061 atgcttaatc ttagattgat actagagagc ttgggctttg ttttgtcagg tttgccctat
    36121 accttaggca tttctttttt aagctttcta acaggccttt tgctgggctt gcttttagcc
    36181 tttttaaggc gttctactag tcactttagt cattatctgg tcaggagcta tgtgtccata
    36241 atgcgtggcg ttcctatgat tgtggtgctc tttgtccttt attttgggct tccctattat
    36301 ggcttagaac tgtctgcctt gttatgtgcc tatttgggct tttcactggt tagtgcagcc
    36361 tatatctctg aggtctttcg tgcctcgatt gatgctattg atcagggaca atgggaggca
    36421 gcaagggctt tggggctgcc ttatgtcagc attgtcaagc atgtgattct gcctcaggcc
    36481 tttcgtattg ctattccgcc tttaggaaat gttgtgattg atatggtcaa aagttcgtct
    36541 ttggcagcta tgattaccgt tcctgatatt tttcaaaagg ctaaaattat tggtggcagg
    36601 gagtgggatt acatgtctat gtatatcttg gttgccttta tttattgggt gattgccttt
    36661 ttgctggagc gctgtcaggg ctttttagaa aagaggctgc gcttactctc ttaaaaaccg
    36721 aatatttacc ctagaaatat tgtatttcta gggtttttat gataaaaata tgatagacta
    36781 aagtagccta atcagttagt tagctttgtc aagaactgac tggctagagt gttggaggta
    36841 ggatatggca gactctattg tatttcggaa aaatcatatg atttcaactc aggcctttgc
    36901 tcgagtgctg gaagcctcag ggattaaaag accgactaag gacgaggcta gattatcgca
    36961 aatgctaaag cattccaatt atctatggac agcatgggaa ggtgacaagt tagttggtgt
    37021 tgctagagcc cttactgact atgcttatgt ctgctatatt tctgacctag cagttgatca
    37081 ggcatatcag ggtcaaggga taggcaagca attgctgtct tttatctcag aggatcttgg
    37141 agatgctgtt gctcttgtat tgctgtcagc accttcggcg atgtcctatt accctaagct
    37201 tggctttgaa caatcagaca aagccttcat tattccacga aaaccgtttt agagaggtat
    37261 ctaatgacac attcagcttg gcatgatgag attaagcaag tgttacctaa ggattattat
    37321 cggcgtatca atcgcttttt agatgaggtc tatgcgactg gagtggttta cccgcccaga
    37381 gacaatgtgt ttaaggcctt acaggtaacg ccattagaag agacaagagt gcttatttta
    37441 gggcaggacc cttatcatgg ccctcttcaa gctcagggac tttccttttc agtgcctgac
    37501 tccattcctg ctccgccatc tttgcaaaat attttggagg aattagcagc agatattgga
    37561 gtaaggaatc atcacgatct tagcagctgg gctgagcagg gagtgttgct cttgaatgcc
    37621 tgcttgaccg ttccagaagg acgcgccaat gggcatgcag gtctcatctg ggagcccttt
    37681 accgatgcgg ttataaaggt cttgaatgct aaggataggc ctgttgtgtt tatcctctgg
    37741 ggagcctatg cgagaagaaa gaaggccttg attactaatc cgattcacca tgttatcgaa
    37801 agccctcacc ctagccctct gtcagcctat cgtggctttt ttggcagcaa gcccttttca
    37861 agagctaacg ccattttaga aaaagaaggc ctaggacaga ttgactggct gcgctaggca
    37921 ttgaggcagg ctattatggc taagcaggac gatttaccaa taaagtatcc ggctttggag
    37981 acttgggtat acctagctaa atagagattg atgatatcag ggatcaagac agttacgtcc
    38041 gatatgtcaa gcaaaacaaa taatcactgc ctagataaat cagaaattgc tagggttatg
    38101 cttgattatc ctgataagca gataagtaga tttgacatag gaggggtcat gttattaatt
    38161 aaaaatgggc gtgtgatgga tccaaaatca cagctagatc aggtggcaga tgtcttaatt
    38221 gataatggaa ggattttacg gattgctcca gacattgagc atgatgaggt agagcagatc
    38281 gatgccagtg gacttgttgt tgctcctggt ttagtggata ttcatgttca ttttagagag
    38341 ccgggtcaaa cgcacaagga ggacattcat acaggtgctc tggcagcagc tgctggtggg
    38401 gtgacaacag tagtcatgat ggcaaacacc aatcctgtta tatcagatac ggaaacctta
    38461 caggctgttc tagcaagtgc tgctaaagaa aaaattaaca tttataccaa tgctagtgtg
    38521 accaagcggt tcaatggcca agagctaaca gactttaaag cgctcttagc agctggtgcg
    38581 gtcagttttt ctgatgatgg cattccttta gagagctcca aggtcttaaa ggaagcattg
    38641 gatttggcta aggccaacaa gaccttcatt gccctgcatg aggaggatcc ccaattaaac
    38701 ggtgtccttg gcttcaatga gcatatcgct aaggatcatt ttcatttttg tggcgctact
    38761 ggtgtggcag aatatagtat gattgccaga gatgtgatga ttgcctatga tcgacaagct
    38821 catgttcata ttcaacattt atctaaggct gagtctgtta aggtagttgc ctttgctcag
    38881 cagttaggtg ccaaggtcac agccgaggca acaccgcagc atttttctaa aacagaagac
    38941 cttttacggc ttgcaggggc aaatgccaag atgaatccgc ctctaagaac agaacaagat
    39001 agattagcag ttattgaggg gctcaaatca ggtgtcatag ctattattgc aacggatcat
    39061 gcaccacatc atcgtgatga aaaggccgtt gctgatctga ccaaggcacc atctggaatg
    39121 accggcttag aaacctcatt gtcattaggc ctgacaaatc ttgtggagcc gagccatctt
    39181 tcattgatgg cgttattaga gaaaatgacc attaatccag cctcactata tagctttgat
    39241 gctggttatt tggctgagtc tggccctgct gatcttgtta tttttgctga caaggaggag
    39301 cgtttggtaa cagaagcctt tgcttcaaag gctagtaatt caccttttat tggcgaaacc
    39361 ctaaagggag ttgtgaaata caccattgct aagggacaaa ttgtttatca ggcagacaac
    39421 taatcaacac ttaaaaagct gagcatctga tagtaactga tgctcagctt tttgatttag
    39481 tgatggcttg cgggctgctg cttgcttaag ttcaagcccc aaggaatgag attttcagat
    39541 tgctgcttga ttcgcttcat attatcctga tgccttagga taatgattgc tgctagcaca
    39601 acgatggtaa tggttaatag ccaatcgtag ctaggcaata aaaagtgggc ggcaggaaaa
    39661 gtcagaacgc taatcacagc tactacagac gctgttagac tagctagtga aatcatgcta
    39721 aataaataaa gcgttagcac aaacacagcc gctaaaaaaa ggagatagag tggggcaaag
    39781 cctagcaaga caccagcact ggttgcgact gcctttcctc ccttgaagcc agcgaaaata
    39841 ggaaaggtat gccctaggac agcaaaaaag ccaatagtaa ttggtgagat attgctagcg
    39901 ccaaccaaaa ccggaagaag cgtggcaagc gtgcccttaa aaatatcaat caataaggtt
    39961 gcagcaccag cttttagccc aagaatccga aacgtattgg tcgtaccggt attacctgag
    40021 ccatgctcac gcaggttgat gttatagaaa tactgtccaa tccataagcc tgttggaatg
    40081 gagccaagta aatatgctgt aagaattaat aggatcaatt tcataacata cattatatca
    40141 taatgattga tttaagcgga agcagttaca aagaattacg aaaaaatctt aaattatttt
    40201 gcaaaattct caaaaaacct gtaagataaa aaagatgaaa acgtctggag gtcaacttgg
    40261 ctaagaaaga aataagcata acaaattata atgatgatgc cattcaggtc ctagagggct
    40321 tagaggcagt tcgtaaaaga ccagggatgt atatcggatc aaccgatgca accggacttc
    40381 accatttgat ttgggagatt gtcgacaatg ctgttgacga ggccttatct ggctttggaa
    40441 atgagatcga tgtgacgcta aacaaggatg gttctgccac catttctgac agcggacgag
    40501 gcatgccgac cggacagcac gcccttggta taccaactgt tcaggtcatc tttaccatct
    40561 tgcatgcagg tggtaaattt ggtcaaggag gctataaaac ctcaggaggc ctgcatggtg
    40621 tgggctcttc agttgtaaat gccctatcgt catggctaga ggtggaaatc acgagagacg
    40681 gagcggttta caagcagcgc tttgaaaatg gcggtaggcc agtgacaggc ttagaaaaaa
    40741 tagctacagc tccaaaaagc aaatcaggga caagggttac tttcatgcct gatgacaaga
    40801 ttttttcgac aactgagttc aagtggaata ctatcgcaga gcgtctaaag gaatctgctt
    40861 ttctgctaaa gacggttaaa atgaccctga ctgatctacg aggtgacgat ccggtcgttg
    40921 aggaatttca ttatgaaaat ggtgttcagg attttgttgc ctatctcaat gaggacaagg
    40981 aaaccttgac tcctgtgatt tacatggaag ggcaggagca ggattttcag gttgaggtcg
    41041 ctttgcaata caatgatggg ttttcagata acattttgtc ctttgttaac aatgttagga
    41101 caaaggacgg tggcagccat gaaactggct taaaatcagc tattacaaag gccatgaatg
    41161 actatgcccg caaaaccagc ctactaaagg aaaaggataa aaacttggag ggctcagatt
    41221 atcgtgaggg cttgtctgca gtgttatcga tccttgtacc agagcagcat ttgcaatttg
    41281 aagggcaaac aaaggacaag ctaggaagcc cactggcaag gccgatcgtt gagagcattg
    41341 tatcagaaaa gctgaccttc tttttacttg aaaatggtga gctggcaggt catttgattc
    41401 gtaaggctat caaggcaaga gacgcgcgtg aggcagccag aagagcgcgt gatgagtctc
    41461 gaaatggtaa gaaaaacaaa aaggacaagg ggcttctttc tgggaaatta actccagccc
    41521 agtccaaaaa tcctaagaaa aacgagctgt acctagtcga gggggactca gctggaggct
    41581 cagctaagca gggcagggat cgtaaatttc aggcaattct ccccttacgt ggtaaggttt
    41641 tgaacacaga aaaggccaag atggctgata ttctcaaaaa tgaggaaatc aatacaatgg
    41701 tttataccat tggcgcaggt gttggtgctg atttcaatct tgatgatatt aattacgaca
    41761 agattattat catgaccgat gctgatacgg atggggctca tattcagacc ctgctgctga
    41821 cctttttcta ccgttatatg cggccgctgg ttgaagcagg acatgtctat attgccttgc
    41881 ctcctcttta taaaatgtca aagggtaaag gcaaatcgga gaaggtttcc tatgcttgga
    41941 cagatggtga gctggaggat cttcgcaagg aatttggtaa aggtgcaagt ctccaacgct
    42001 ataagggact tggggagatg aatgccgatc agctatggga aaccacgatg gaccctgaca
    42061 cacgaaccct tatccgagtg acgattgatg acctggctag ggcagagcga cgcgtttcag
    42121 tcctcatggg agacaaggct gccccacgcc gtcaatggat tgaggacaat gtcaccttta
    42181 ccttggagga aaatacggtt ttttaaggca tttttcctaa ggagggttct aaaatatctc
    42241 atatcaaatt gctattcatg tgctcagcat tcatttatca aggattgtaa tcattgaggt
    42301 aacagtgatg aagctagata tttgtcaaca aagctacagt cttcagtggg gaggcaccta
    42361 ttattttgca ttgacagatt atcccaatat caaggcttgg gaactggaaa agctagcagc
    42421 cttttgtgcc tacgaaaaat ggaatcatcg tcaaacagac attagctgtc aggacagcaa
    42481 gcttcttgaa gaggttcatc aatttcttga agcacatgct tgtgcctatc tctttaggcc
    42541 tagctgtaaa ttggtggctt caacatttaa catcaatgga gaggcagtct gttgtcctta
    42601 tttaagtcat acctgcactg tagcggctgc tctaagcatt tttaagacag gaaggctatt
    42661 gtctgctgta agagcttttg gggtaacggc acaggagttg gctaggagtg atcgaaatgc
    42721 tgctggtgat cctgctgatt attttcatta tgtgatgctt ggctggtcca atacgacctc
    42781 aggctatcgc ttggctatgg agagattgct taatcgtatg ccaaatgaaa aggacttaag
    42841 agagcatttt gtacccggag ttagctttca ctatagctat tctgatattt gtcagatgaa
    42901 aggctatgtt tttgatggct atcaccctgc caagatcaaa gacgagctta gtttggagga
    42961 attgcaggct tgcattattc ctaaaagctg gcagcagcgc tttgaagcaa ttattccaaa
    43021 ggccttacgc tcaagggttc attacctaga ctataaaggc gaaggcttgg tcgagtggtc
    43081 tgatagggtt tatcagctgt taagagtgat cagtgacagc tagctgtaaa taggctagct
    43141 ttatactatt ttttgaatat aatagacaat ctaacagaaa ggaaagctca gtgagaggtc
    43201 tcttgctggg tgtgggatgg atttcctaga aactgctaat cctagcgata ggggagcgta
    43261 gcgagcccat tctgaaagct cctgccgtag tgaaaagaag ataatcgctt acgattatct
    43321 tcgagggaaa tttcgagccg aagtctcgaa atttaggaat ggaaccgtag gttcgcttct
    43381 gtccccacta cctaaaggaa ctttcaaaaa aaactaatta aagaaagaga tatctttctg
    43441 aaagaaacaa agaaaggaat gttcagctag tttactaact gaacacggga ctatttttcc
    43501 tagaaaaatc ggtaacctcc tagtgtccaa ggacacgtcg tcagttccag cattttttac
    43561 ggaaaaattt cgcaagcgaa acgtcccttt gtatcttatg agtaatattc aaaacatgtc
    43621 ccttgaggac atcatgggag agcgttttgg acgctactcc aaatacatca ttcaggagcg
    43681 agcgcttcct gatattcgag atggtctaaa gcctgttcag cgccgcattc tttattctat
    43741 gaataaggac ggtaatacct ttgaaaaggg ctaccgcaag tcagccaagt ctgttggtaa
    43801 tatcatgggc aatttccacc cgcatggaga ttcttcgatc tatgacgcta tggtacgcat
    43861 gagtcaggat tggaagaatc gtgaaattct tgtggaaatg catggcaata acggctcgat
    43921 ggacggtgat ccaccggcag ctatgcggta cactgaggca agattatctg aaattgctgg
    43981 ttacctgcta caggacatcg ataaaaaaac agtgccattt gcttggaatt ttgacgatac
    44041 cgaaaaagag ccaacagtat tgccagctgc ctttccaaat ctattggtca atggctcatc
    44101 agggatctca gcaggctatg ctacagatat tccaccacat aatttgtcag aggtgatcga
    44161 tgctgttatt tatatgattg accacccaaa tgccaagctg gataagttaa tggagctatt
    44221 gccgggtcct gattttccaa caggtggtat tatccaagga gcagccgaaa ttaaaaaagc
    44281 ctacgaaaca ggtaagagcc gcgttgttgt tcgctccaga actgaaattg aggatctaaa
    44341 gggaggcaag cagcagatca ttgtgaccga acttccttat gaggtcaata aagctgtcct
    44401 agttaaaaaa attgatgatg ttcgggttaa taacaaggtt ccagacatag cagaggtgcg
    44461 tgatgagtca gaccgtacag ggctacgcat tgctattgag ctcaaaaaag acgctgacag
    44521 ccaaaccatc ttgaattatt tgttgaagta taccgagctt caagtcaatt ataattttaa
    44581 tatggttgcg attgatcatt ttacgcctcg tcaggttgga ttgcaaaaaa tcttatcaag
    44641 ctatatcgct caccgcaaaa gtattattat caagcgctct cagtttgaca aggaaaaggc
    44701 tgaaaagaga ttgcatattg ttgagggctt gatacgtgtc ttatctattt tagatgagat
    44761 tatcgcgctg atccgagctt ctgacaataa ggctgacgcc aaggaaaacc taaaggtcag
    44821 ctatgatttt tcagaggaac aagcagaggc tatcgtaacc ttacagcttt atcgactgac
    44881 caatacagat attgttaccc tccagcagga agaacatgac ctaagagagc tcatcacaac
    44941 tctctctgcc attattggtg atgaagcaac catgtataac gtgatgaagc gtgagctaag
    45001 agaggtcaag aaaaagtttg cagggccgcg tttatcagag ctgcaggctg aaagccaagc
    45061 gattgaaatt gattctgcta gtcttatttt ggaggaagaa acctttgtca gtgtgactca
    45121 gggaggctat atcaagcgaa caagccctag gtcatttcac gcctcaagcc ttgaggaaat
    45181 tggtaagcgt gatgatgatc atctgatctt tgttaagcag gctaagacaa cagaccacct
    45241 gttactcttt actaatttag gtaatgttat ttaccgtccg gtctatgagc tgactgactt
    45301 gcgctggaag gacatcgggg agcatttatc acaggctatt gctaattttg ctgctgatga
    45361 gctggtgata tatgctgagt tgatccagtc ctttgaagag ggactatata tctcagtgac
    45421 acagcatgga ctgattaaac ggtttgagcg caaggagctg acgccttggc gaacctacaa
    45481 atcaaaatca attaaatacg ccaagctaaa agacatagat gatcgcattg tggcaatagc
    45541 accaattatc atggaagatc ttcttttggt gacgcagcag ggctacgcct tgcggttttc
    45601 tagccaagaa ataccgattc agggcctaaa ggctgccgga gttaaaggaa ttaacctaaa
    45661 ggctcaggat tacttggttt ctgcctgccc agtcaatgct gattccttct ttgtgctgac
    45721 gcaaagagga gcactaaagc gagtggcgat tgctgatatt ccacagacca gccgagctaa
    45781 cagaggtctg ccggtgttac gagaattaaa gaccaagcca cacagagttt tcttggcagg
    45841 aatggtaaaa ggagatacta caacaggtac cattgactta tttacacatg attcagagga
    45901 cacagctagt gaccagcaat tagaggttat tagtaagact ggtcaacaat accagcttgc
    45961 tctcaatagc ctgtctctat cagataggac aagtaatggc tcctttattt cagagagcat
    46021 ttcagatcag gaggtcgctg ctgcaaggct catctagcca aagctttttc gctgtaccag
    46081 tgagggctct gagtctttca tcgaaaaaag atgcaaaaca atgaagaaaa gaatacaaaa
    46141 agaaaagagg taggataatg acaacagcta ttgattggga aaacttaggc tttgaatacc
    46201 gtaagctgcc atttcgctat gtatcatatt acaaggacgg caaatgggac gcaggtcgct
    46261 taacagaaga tgctaccctg cacatctcag aaagtgcacc agctctgcat tatgggcaac
    46321 aagcctttga aggcttaaag gcctatcgca ctaagaacgg ctctattcag ctatttcgcc
    46381 cagaccgcaa tgcagctcgc ttacaggcaa cagctgaccg tttgctgatg ccacaggtat
    46441 ctaccgagca attcattgac gccgttaagc aagtggtaaa ggcaaatgag gattttgtac
    46501 cgccatatgg aactggtgct accctttacc ttagaccctt gttaattggt gttggcgata
    46561 ttatcggtgt taagcctgct aacgaatata tatttatagt ttttgccatg cctgttggca
    46621 attactttaa aggcgggctt gcgccgacca actttatcgt ctctgaggat tatgatagag
    46681 cagctcctta tggcactgga gctgccaagg ttggtgggaa ctatgcaggt agcttattgc
    46741 caggaaaagc agctaagaca gcagggtatt cagatgtgat ttacctagat ccagcaactc
    46801 acactaagat tgaagaggtc ggagccgcta atttctttgg catcactgcc aataatgaat
    46861 ttattacgcc gcttagccca tcaatcttgc cttcaattac caaatactcc ttactccaat
    46921 tagccgaaga aaggcttggt atgaccgcta ttgagggtga tgtgccgatt aatgatttgg
    46981 accgatttgt tgaggcagga gcttgtggga cagctgctgt gatctcacca attggaggca
    47041 ttcagtatca ggataagcta catgtctttt acagcgagac tgaggttggt ccagtgacac
    47101 gtcgattata cgatgagctg gtcggtatcc aattcggtga tatcgaagca ccagaaggct
    47161 ggattgtagc tattgattaa aataagtgaa gcttgctatt gcaagctctt ttgattttgt
    47221 gtaaaataga caaggcgagg tgaagtgatg agtaaaaaag agaaaaaaat tgaactgcaa
    47281 ttatgcgatc aacaagtaac agtcaacaat accaagatag acggttatca gttacaaatt
    47341 ggcaagcgtg tcgttggcga gattgcagag cttgatggca agtttgctgt cttaaaagac
    47401 agcacagtag atgctttttt taaaacatta gagcaagcag ttgaaaatat tattgaaaac
    47461 tataatttga accactaaaa atgcttaaaa agacttgtca gcttacaaaa actatggtag
    47521 aatagttttt gttgttacgg aaagatagcg aagaggctaa acgcggcgga ctgtaaatcc
    47581 gctcctttgg gttcgggggt tcgaatccct ctctttccat gcctaagcta ttaggttcat
    47641 tgttttaatg atgatattgg ggtatagcca agcggtaagg caagggactt tgactccctc
    47701 atgcgttggt tcgaatccag ctaccccagt cagaggtatc agattagcgt ctgagatcgt
    47761 caaggataaa agttgttgtc attgcgggtt accttgagaa aatatattgt tatcaaaagc
    47821 tagcataagc tagcttttgt tggaggattt tttagaatga atgaatttga agatttgcta
    47881 aacagtgtta gcgaagtcaa tcctggtgat gttgtcactg cggaggtttt gacagttgat
    47941 aacggtcaag caaacgttgt tattgaaggc acaggtgttg aaggcgtttt gacacttcgt
    48001 gaattgacta acgatcgtga agctgatatt aatgactatg ttaaagctgg cgacaccgtt
    48061 gaagtgcttg ttcttcgtca agttgtaggt aaagatactg atacagttac tttcctagta
    48121 tctaaaaaac gtttggaagc tcgtaaggca tgggacaagc ttattggtcg tgaaggtgaa
    48181 gtcgttactg ttaaggggac tcgtgctgtt aaaggtggac tttcagttga atttgaaggg
    48241 cttcgcggat ttatccctgc ttcaatgatt gacactcgtt ttgttcgcaa tacagaaaag
    48301 tttgtcggtc aagaatttga cgctaaaatc aaagaagttg atgcagcaga aaaccgcttt
    48361 atcttatcac gtcgtgaggt tgttgaagaa gcagctaagc aagcacgtga caaagtcttt
    48421 tcaacacttt cagaaggttc agtggtaact ggtactgttg cgcgtttgac aagctttggt
    48481 gcttttattg atcttggtgg tgttgacggt cttgttcacg taactgagct ctcacatgag
    48541 cgtaatgtgt cgcctaaatc agttgtttct gttggtgaag aggttgaggt gaaggtactt
    48601 gctcttgatg aggaagcagg tcgcgtatca ctatcactta aagcaacaac acctggacct
    48661 tgggatggcg ttgagcaaaa gcttgcacaa ggtgatgtta tcgaaggtaa ggttaagcgc
    48721 ttgactgact ttggtgcttt tgttgaggta ttacctggaa ttgatggact tgtacacatt
    48781 tcacaaatct cacacaagcg tgttgaaaat ccaaaggacg tgcttactgt aggtcaagag
    48841 gtaactgtta aggttcttga cgttaacgct gctgatgagc gtgtatcatt gtcaatcaag
    48901 gcacttgaag agcgtccagc acaagcagag ggtgaaaagg aagaaaaacg tcaatcacgt
    48961 ccacgtcatc aaaaacgtga agctaagcgt gattatgagc ttccagaaac acaaactgga
    49021 ttttcaatgg ctgacctttt tggtgatatt gaattataat actataaaaa
//
LOCUS       DARYNN010000011        48181 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.011, whole genome shotgun sequence.
ACCESSION   DARYNN010000011 DARYNN010000000
VERSION     DARYNN010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48181)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48181)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48181
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.011"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            121..255
                     /gene="rpmH"
                     /locus_tag="TVB59_000566"
     CDS             121..255
                     /gene="rpmH"
                     /locus_tag="TVB59_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEL1009500.1"
                     /translation="MKRTYQPSKIRRQRKHGFRHRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            542..1267
                     /locus_tag="TVB59_000567"
                     /pseudo
     CDS             542..1267
                     /locus_tag="TVB59_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678571.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
     gene            1286..2599
                     /locus_tag="TVB59_000568"
     CDS             1286..2599
                     /locus_tag="TVB59_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL1009501.1"
                     /translation="MKMKKLASFVMLGASVLGLAACGSSSKEADKSDSAAKTEITWWA
                     FPTFTQEKADDSVGTYEKKIIAAFEKANPDIKVKLETIDFTSGPEKITTAIEAGTAPD
                     VLFDAPGRIIEYGKNGKLADLNDLFTDEFIKDVNNDNIIQASKAGDTAYMYPISSAPF
                     YMALNKKMLKDAGVLDLVKEGWTTDDFEKVLKALKDKGYNPGSFFANGQGGDQGPRAF
                     FANLYSSRITNDDVTKYTTDDANSVKSMEKIASWIKDGLLMNGSQYDGSADIQNFANG
                     QTSFTILWSPAQAGTQAKLLEASKVDYVEVPFPSEDGKPELEYLVNGFAVFNNKDDKK
                     IEASKKFIQFIADDKEWGPKNVVRTGAFPVRSSYGNLYDDERMAMVSKWTQYYSPYYN
                     TIDGFAEMRTLWFPMVQAVSNGDEKPAAALKAFTEKANKTIEKAQ"
     gene            2700..3587
                     /locus_tag="TVB59_000569"
     CDS             2700..3587
                     /locus_tag="TVB59_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003041053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1009502.1"
                     /translation="MNVNKLKMRETLVSYAFLAPVLVFFVVFVLVPMIMGFVTSFFNY
                     TMTDFTFVGLDNYVRMFQDPVFIKSLINTLIIVVGSVPIVVFFSLFVATKTYNKHVIS
                     RSFYRAVFFLPVVTGSVAVTVVWKWIYDPMSGILNYVLKYGHVIEQNISWLGDKHWAL
                     LAIIVILLTTSVGQPIILYIAAMGNIDNSLVEAARVDGATELQVFWKIKWPSLLPTTL
                     YITVITTINSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFKLSEYGYANTMGVFLAI
                     LISLISFAQFKFLGNDVEY"
     gene            3600..4430
                     /locus_tag="TVB59_000570"
     CDS             3600..4430
                     /locus_tag="TVB59_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEL1009503.1"
                     /translation="MRKKKLTASDILTTAILCLLTILFIFPFYWIMTGAFKSQPDTIV
                     VPPQWWPKAPTVENFKALIIQNPALKWLWNSIYISVATMLLVCGTSSLAGYALAKKRF
                     YGQRLLFSIFIAAMALPKQVVLVPLVRIVNFMGIHDTLAAVILPLVGWPFGVFLMKQF
                     SENIPTELLESAKIDGCGEIRTFFNVAFPIIKPGFAALAIFTFINTWNDYFMQLVMLT
                     SRDHLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGAVKG
                     "
     gene            4446..4901
                     /locus_tag="TVB59_000571"
     CDS             4446..4901
                     /locus_tag="TVB59_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEL1009504.1"
                     /translation="MLYDVLENIRRYKGIHRHLDVAIDFLLTRDLRSLTDGKHVILED
                     KVVLFIQHNCLNKEDNALFEYHKRYADLHLLVEGNERVRYGLGYKQEAVSFDEASDIG
                     FVTCERTYDLDLGNDCFCYFFPNEAHQPNGFNDDGDAVTKCLIKVLMED"
     gene            4926..5576
                     /locus_tag="TVB59_000572"
     CDS             4926..5576
                     /locus_tag="TVB59_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEL1009505.1"
                     /translation="MSSKKRKLMQSIFSLDSKWLRASATIFDLIVLNLLFVLSCLPVV
                     TIGIAKMALYASLRDYRQGDIGSVVGVYGSYLRRFAKRGLQLGILEVLLTSFILVDLY
                     LIQAQVSLFFQLFKISCIAILFVAIMVFLYAYPLAMRYDLPLMSLFQRSFILLSLFFP
                     FSFAFLAVMLLVVFLLQLSPLSLLGGLSLLAIIGISSLTYPYVVIMENLLQKVQLY"
     gene            5605..6525
                     /locus_tag="TVB59_000573"
     CDS             5605..6525
                     /locus_tag="TVB59_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEL1009506.1"
                     /translation="MKTLTKYQGIIPAFYACYDAEGNISPERVRALTQYYIDKGVQGL
                     YVNGSSGECIYQSVADRKLVLEHVMAVAKGKLTIINHVACNNTKDSIELAQHAEALGV
                     DAIAAIPPIYFRLPEHAVAAYWNAISAAAPNTDFVIYNIPQLAGIALTPSLYQEMLKN
                     ERVIGVKNSSMPVQDIQTFCAIGGDDHLVFNGPDEQFLGGRLMGASAGIGGTYGAMPE
                     LFLRLNQLIKDKDLETAKALQYAINDIIGLLVSAHGNMYGVIKEVLRINERLDIGSVR
                     SPLPELTENDLVICQQAAALIKQTKEQFCS"
     gene            6540..7424
                     /locus_tag="TVB59_000574"
     CDS             6540..7424
                     /locus_tag="TVB59_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEL1009507.1"
                     /translation="MKRYLAIDIGGTAIKYGLMTETADILEKHEIATEAHKGGPAILD
                     KVKDLVATYQEAGLAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKRVIEETFGIP
                     CDVENDVNCAGLAEAISGSAKDCPVALCLTIGTGIGGCLLIDSQVFHGSSYSACEVGY
                     IHLPDGAFQDLASTTALVRDVARRHGDAVSDWNGRRIFEEAKAGNHHCIAAIDQLVDY
                     LAQGLANICYVANPNAIVLGGGIMAQKDYLQDKILAALNNYLVPSIAEKTQLRFASHE
                     NNAGMIGAYYHFKHKEQV"
     gene            7424..7696
                     /locus_tag="TVB59_000575"
                     /pseudo
     CDS             7424..7696
                     /locus_tag="TVB59_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514912.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
     gene            complement(7738..8562)
                     /locus_tag="TVB59_000576"
     CDS             complement(7738..8562)
                     /locus_tag="TVB59_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEL1009508.1"
                     /translation="MIHNHRLISKMEAALDSMTSLEKSIAQFFMETDLKVEELTASDM
                     IKRLHVSQAALTRFAKKCGFTGYREFIFECQKSREAMDQKAPNLQNYNTKKVLMNYRE
                     LIEKATELINEKQLQDIAQWIENAERIYFYGKGSSALAAKEFKLRLMRLGVICEALDD
                     TDSFTWVNSSITDKCLVIGFSLSAQTASVLEALQTAGTRGAKTVLLTTQTDEIPYQLD
                     EIVHIATARHLNYGNRISPQFPMLFVTDIIYAYFLEINKEGKTKIFQETIINPSDK"
     gene            8791..9564
                     /locus_tag="TVB59_000577"
     CDS             8791..9564
                     /locus_tag="TVB59_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEL1009509.1"
                     /translation="MIEIFDTHTHLNVDHFSGKEEEELALAKEFGVSYHNVVGFDQET
                     IDQALTLADAYREVYATIGWHPTEAGSYTQAVEDSLIACLKHPKVVALGEIGLDYYWM
                     EDPKEVQIEVFKRQLQLAKDHDLPFVVHTRDALEDTYQVLKEAGVGPRGGIMHSYSGS
                     LEMAQRFVDLGMLISFSGVVTFKKAVDVQEAARHLPLDKLLVETDAPYLAPVPKRGRE
                     NHTAYTRYVVEKIAELRGLSVEEIAAATTANAKRVFRID"
     gene            9536..10132
                     /gene="rnmV"
                     /locus_tag="TVB59_000578"
     CDS             9536..10132
                     /gene="rnmV"
                     /locus_tag="TVB59_000578"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEL1009510.1"
                     /translation="MQRGCLELTEKLKIQEVIVVEGKDDTANLQRFYDVDTYETKGSA
                     ITDEDLERIDRLNKLRGVIVFTDPDYHGERIRKLIMRAVPTARHAFLRRHEAKPRSKS
                     KGRSLGVEHASFEDLQKALSQVTQSFDDESYFDISQTDLIRLGLLLAADSRKRREYLG
                     EVLRIGYSNGKQLLKRLKLFGITLSEVEDVMTSYQTEQ"
     gene            10476..11348
                     /gene="rsmA"
                     /locus_tag="TVB59_000579"
     CDS             10476..11348
                     /gene="rsmA"
                     /locus_tag="TVB59_000579"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015911942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEL1009511.1"
                     /translation="MRIADYSVTKSILDRYGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DKSVNVIEIGPGIGALTEFLAERAAEVMAFEIDERLVPILADTLRDFDNVQVVNQDIL
                     KADLQTQLKQFSNPDLPIKVVANLPYYITTPILMHLIESKIPFQEFVVMMQREVADRI
                     SAEPNTKAYGSLSIAVQYYMTAKIAFVVPRTVFVPAPNVDSAILKMTRRDQPLIEVQD
                     EDFFFRVSRVGFVHRRKTLWNNLVSHFGKAEDTKARLEQGLALAGIKPSIRGEALSIQ
                     DFGRLADALKQVGF"
     gene            11509..12381
                     /gene="rsgA"
                     /locus_tag="TVB59_000580"
     CDS             11509..12381
                     /gene="rsgA"
                     /locus_tag="TVB59_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEL1009512.1"
                     /translation="MQGKIIKALAGFYYVESEGQVYQTRARGNFRKRGQTPYVGDLVE
                     FSAEDNSEGYILAIAERKNSLVRPPIVNIDQAAVIMSAKEPDFNTNLLDRFLILLEHK
                     AIHPIIYISKIDLLEQPESIEAIGQHYRAIGYDFVTSLSHLLPLLAGKTTVFMGQTGV
                     GKSTLLNRIAPELALETGDISDSLGRGRHTTRAVSFYDAYNGKIADTPGFSSLDYGID
                     NAEDLNEAFPELRRLSHSCKFRSCTHTHEPKCAVKEALGNGELWSVRYQNYLQFLSEI
                     ENRRETYQKVSKRK"
     gene            12390..13052
                     /locus_tag="TVB59_000581"
     CDS             12390..13052
                     /locus_tag="TVB59_000581"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEL1009513.1"
                     /translation="MSSLKIAPSILAADYACFAAELARIEKTDAEYVHIDIMDGQFVP
                     NISFGADVVASMRKHSKLVFDCHLMVVNPERYVEAFAQAGADIMTIHVESTLHSHGAL
                     QKIRAAGMKAGVVINPGTPVSAVEPLLSLVDQVLIMTVNPGFGGQAFIPECLEKVAAI
                     AKMRDERGLSFDIEVDGGVDDKTIRACYQAGANVFVAGSYLFKAADLAAQVQTLRAAL
                     NG"
     gene            13045..13677
                     /locus_tag="TVB59_000582"
     CDS             13045..13677
                     /locus_tag="TVB59_000582"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEL1009514.1"
                     /translation="MVKVALFAGGDLSYFTCDFDYFVGIDRGSLFLLENGLPLNMAVG
                     DFDSIPQVAFEVVKEQAELLVQASPEKNDTDTELALKEVFTRFPEAEVTIFGAFGGRL
                     DHLLSNVFLPADPELAPFMAQICLRDQQNAISYRSSGWQTIRQDKDMTYVAFMADGDA
                     DLTITGAKFDLTTSNFFKKKVYASNEFIDQPIKVHVPKGYLIIIQSKDRS"
     gene            13679..14950
                     /locus_tag="TVB59_000583"
     CDS             13679..14950
                     /locus_tag="TVB59_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEL1009515.1"
                     /translation="MDLILFVLVLVLIGLAAYSFVSIKHLQSRLEKALDDNADNLSDQ
                     LTYQLDMANKSQLLELSTVMNRQQNELFQQLMVIRDTLHQGLAENRDRSDQRLETMTQ
                     SLSQAVKNLQDSNEKRLEEMRHTVEEKLEKTLKNRLQTSFEAVSKQLESVNQGLGEMR
                     TVAKDVGTLNKVLSNTKTRGILGELQLGQIVEDIMTANQYEREFATVSGSSDRVEYAI
                     KLPGNGQGDYIYLPIDSKFPLEDYYRLEDAYEAGDRAAIETSRKALLAAIKRFAKSIH
                     SKYLNPPETTNFGIMFLPTEGLYSEVVRNPAFFDSLRREENIVVAGPSTLSALLNSLS
                     VGFKTLNLQKNADDISKILGNVKLEFEKFGGLLAKAQKQLNTANHTLDQLMSTRTKAI
                     VRALATVEGYQDQSTQSLLHIPLLEEADDED"
     gene            14940..15878
                     /locus_tag="TVB59_000584"
     CDS             14940..15878
                     /locus_tag="TVB59_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEL1009516.1"
                     /translation="MKINQMKKDQPFEGFYLIKSAEVRKTRAGKDFIAFTFQDDTGEI
                     SGNLWDAQPYNVEEFVAGKIVFMKGRREVYNGTPQVNQITLRNIRPGEPNDPKEFKEK
                     APVSVTEVRDYLDQMLFKIENATWQRIVRALYRKYDKEFFTYPAAKTNHHAFESGLAY
                     HTATMVRLADSIGDIYPELNKSLLFAGIMLHDLAKVLELTGPDNTEYTIRGNLIGHIA
                     LINEEITKTITELNIDDNKEEVTVLRHVILSHHGQLEYGSPVRPRIMEAEIIHMIDNI
                     DANMMMMSTALSRIGEGEMTNRIFAMDNRSFYKPKY"
     gene            15978..16793
                     /gene="purR"
                     /locus_tag="TVB59_000585"
     CDS             15978..16793
                     /gene="purR"
                     /locus_tag="TVB59_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEL1009517.1"
                     /translation="MKLRRSERMVVISNYLINNPYKLTSLNTFATKYEAAKSSISEDI
                     AIIKKAFEESNIGEIDTLTGASGGVIFTPSISEAEARSIVEELCQRLSESNRILPGGY
                     IYLSDLLSTPKLLQNIGRIIANAFKGQKIDAVMTVATKGVPLANAVANILNVPFVIVR
                     RDLKITEGSTVSVNYASASSYRIEKMFLSKRSLKPNSRVLIVDDFLKGGGTITGMMSL
                     LTEFDSTLVGVAVFAENAQSEREQMSFKSLLKVSEIDVKNNRVVVEVGNIFDK"
     gene            16830..19334
                     /locus_tag="TVB59_000586"
     CDS             16830..19334
                     /locus_tag="TVB59_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC10/PgrA surface exclusion domain-containing
                     protein"
                     /protein_id="HEL1009518.1"
                     /translation="MEQENSRTKHVKSTIALTSTIALLGTSVGVSHQVKADDAKSGDA
                     NTSNTSEATLAKPETLEEAVLAVKATEETLSERKKELAETNTNIAETEGEIANLEATK
                     KEQIAELAKAEELLETYSSMSEEDLAKSIEKHETELETINTELEKATTESQAQAEAVA
                     KQQETIAAEATKADQLATQLTAAEQKVSDLNTMISQPEAIVSEAQAAKEEVKRISDDL
                     AKATANLATVKETVHSQLTSDLAANKAALAAKEAELQRLQNGVATAQLNVAGSNKLIL
                     PKDYPIEEIKKLAASGYIGTAAYNQYYQAVKDTMIAKAEPGAAMNQYVDIPEDLNRVV
                     DPDNLSQEVQNELAQFAAQMINDVRKQLGLVPVTVTVGSQEFARLLTKSYKETHQNTR
                     PSFVYGQVDASGHRGVGPHDQTIIEESAVKVGLRQKDDNMYENLGAFNEVHTVNGIKR
                     GIYDSIKYMLFTDHLHGNTYGHAVNFLRVDKTDPNAPVYLGFSTSNVESLNEHFVIFP
                     ESDIVDATRFSTTEIPKSGQVIDRSASIQALTNDIASIKGKIASLESRLADPSSEAEV
                     TAAQAKISQLQHQLEAAQAKSHKLDQQVEQLANTKDSLRTQLLAAKEEQAQLKANLDK
                     ALALLASSKATLHKLEAAMEEAKARVAGLASQKAQLEDLLAFEKNPNRIELAQEKVAA
                     AKKALADTEDKLLAAQASLSDLQAQRARLQLSIATIEQQLVLLKNLVQEKQRLRLEAE
                     RLNSMSETRQLLNQLAPQAAKAGVGSELVATGLLVSKVASAIAKQSPTSHSYGAGAAS
                     HAAVDDNTQRAVQAGMVMLAAAGLATVKLKKGSKKR"
     gene            19517..19930
                     /gene="rpsL"
                     /locus_tag="TVB59_000587"
     CDS             19517..19930
                     /gene="rpsL"
                     /locus_tag="TVB59_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEL1009519.1"
                     /translation="MPTINQLVRKPRKSKIEKSDSPALNIGYNSHKKVHTKLAAPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLIRGGRVKD
                     LPGVRYHIVRGALDTAGVADRKQGRSKYGAKRPKG"
     gene            19951..20421
                     /gene="rpsG"
                     /locus_tag="TVB59_000588"
     CDS             19951..20421
                     /gene="rpsG"
                     /locus_tag="TVB59_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEL1009520.1"
                     /translation="MSRKNRAPKREVLPDPLYNSKLVTRLINRIMLDGKRGTASSIVY
                     DAFSEIKEATGNDALEVFETAMDNIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTASRARGEHTMKDRLAKEIMDAANNTGASVKKREDTHKMAEANRAFAHFRW"
     gene            20964..23042
                     /gene="fusA"
                     /locus_tag="TVB59_000589"
     CDS             20964..23042
                     /gene="fusA"
                     /locus_tag="TVB59_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEL1009521.1"
                     /translation="MAREFSLAKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWDGHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVQTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPEEYLEQAQEYREKLIEAV
                     AETDEDLMMKYLEGEEITNEELVAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVIA
                     YLPSPLDIPAIKGVNPDTDAEEERPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     NSGSYVMNTSKGKRERIGRILQMHANSRQEIETVYAGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESIEVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIA
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLIESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLALKEAAKTAQPAILEPMMLVTITAPEDNLGDVMGHVTA
                     RRGRVDGMEAHGTSQIVRAYVPLAEMFGYATVLRSATQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGE"
     gene            23423..24433
                     /gene="gap"
                     /locus_tag="TVB59_000590"
     CDS             23423..24433
                     /gene="gap"
                     /locus_tag="TVB59_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEL1009522.1"
                     /translation="MVVKVGINGFGRIGRLAFRLIQNVEGVEVTRINDLTDPAMLAYL
                     LKYDSTQGRFDGDVEVVEGGFNVNGKFVKVSAEANPENIDWASQEVDIVLEATGFFAS
                     KAGAEKHLHANGAKKVVITAPGGNDVKTVVFNTNHEILDGTETVISGASCTTNCLAPM
                     AKVLQDKFGVVEGLMTTIHGYTGDQMTLDAPHRKGDFRRARAAAVNIVPNSTGAAKAI
                     GLVIPELNGKLDGAAQRVPVPTGSVTELVSVLEKDVTADEVNAAMKAAANDSFGYTED
                     QIVSSDVVGIHYGSLFDATQTKVLTVDGKQLVKTVSWYDNEMSYTAQLVRTLEYFAKI
                     AK"
     gene            24977..25831
                     /locus_tag="TVB59_000591"
     CDS             24977..25831
                     /locus_tag="TVB59_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase, lipoprotein e(P4) family"
                     /protein_id="HEL1009523.1"
                     /translation="MTSKKILNLVSLGLSLVLISGCTTNGEKKAAPSQDKDKQEKVVR
                     LTNDQLRARENTMATLWYQQSEEAKALYLQGYQVAKQRLDTLLSQATDKPYSIVLDID
                     ETVLDNSPYQAKNIKEGTGFTPDSWDKWVQKKSAKAVAGAKDFLQYANDKGVQIYYVS
                     DRTTKQVEPTMENLEKEGIPVQGKDHFLFLEEGVKSKEGRRQKVQETTNLVLLFGDNL
                     LDFAEFSKTSHEDRRKLLDQLHAEFGSKFIIFPNPMYGSWESSVYNGQKLDSEGQIKA
                     RDKALEAY"
     gene            26041..27237
                     /locus_tag="TVB59_000592"
     CDS             26041..27237
                     /locus_tag="TVB59_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEL1009524.1"
                     /translation="MAKLTVKDLDLKGKKVLVRVDFNVPLKNGVITNDNRISAALPTI
                     KYIIEHGGRAILFSHLGRVKEEADKEGKSLAPVAKNLAEKLGQEVIFPGSTRGAELEA
                     AIDALEDGQVLLVENTRFEDIDGKKESKNDPELGKYWASLGEGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIKEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYEAQGIEIGNSLCEEDKLDVAKSLLEKSNGKLVLPVDSKEANAF
                     ADYTEVKVTEGEAVDTGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQEG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKELPGL
                     AALTEK"
     gene            27660..28181
                     /locus_tag="TVB59_000593"
     CDS             27660..28181
                     /locus_tag="TVB59_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEL1009525.1"
                     /translation="MNYHFDASKLKLGMRTFKTGLAVFFVLLLFHFFDFQGLQIGALT
                     AVFSLRESFDKTISFGTSRILGNSIGGFFAIIFYLLDTLFQGAFWVTLVFVPILTMLT
                     IMFNVAFNNQSGIIGAVAALLIITLSIPTGEAFMYVIARVFETFCGVFIAILVNTDVE
                     LIRNKWLSRKLKK"
     gene            28257..28628
                     /locus_tag="TVB59_000594"
     CDS             28257..28628
                     /locus_tag="TVB59_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEL1009526.1"
                     /translation="MKEKELRRSMAVFPIGAVMTLTDLSARQIRYYEDQELIKPERTE
                     GNRRLFSLNDMDRLLEIKDFLDEGLNIAAIKREYAERQDKLMQKQKVLTDADVRRILH
                     DELLNQGGFSTPSQHIGNFRI"
     gene            28665..30011
                     /gene="glnA"
                     /locus_tag="TVB59_000595"
     CDS             28665..30011
                     /gene="glnA"
                     /locus_tag="TVB59_000595"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEL1009527.1"
                     /translation="MAITAADVRREVKEKHVTFLRLMFTDIMGVMKNVEIPATEEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWIVFPWGDENGTVGGLICDIYTAEG
                     KPFAGDPRGNLKRALKHMDEVGYQSFNLGPEPEFFLFKIDEAGEPTLEVNDKGGYFDL
                     APIDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYADALKACDNIQIFKLV
                     VKTIAREHGLYATFMAKPKFGIAGSGMHCNMSLFDKGGNNAFYDENDKRGMKLSDDAY
                     YFLGGLMKHAYNYTAITNPTVNSYKRLVPGYEAPVYVAWAGSNRSPLIRVPASRGMGT
                     RLELRSVDPTANPYLALAVLLEAGLDGIINKIEAPAPIEANIYMMTAEERNAAGIVDL
                     PSTLHNALKALQKDEVIQKALGDHIYTNFLEAKRIEWSSYATFVSQWEIDNYLHNY"
     gene            30244..31902
                     /locus_tag="TVB59_000596"
     CDS             30244..31902
                     /locus_tag="TVB59_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL1009528.1"
                     /translation="MTVLGTKACKRLGLAAVTLASVAALMACGNKQSASTDKKSEINW
                     YTPTEIITLDISKNTDTYSALAIGNSGSNLLRADAKGKLQPDLAEKVDVSEDGLTYTA
                     TLRDGLKWSDGSDLTAEDFVYSWQRMVDPKTASEYAYLATESHLKNAEDINSGKNPDL
                     DSLGVKADGNKVIFTLTEPAPQFKSLLSFSNFVPQKESFVKDAGKDYGTTSEKQIYSG
                     PYIVKDWNGTSGTFKLVKNKNYWDAKNVKTETVNVQTVKKPDTAVQMYKQGKLDFANI
                     SGTSAIYNANKKHKDVVPVLEATTAYIVYNQTGAIEGLNSLKIRQALNLATDRKGIVS
                     AAVDTGSKPATALVPTGLAKLSDGTDLTEHVAPGYKYDDKEAAKLFKEGLAELGKDAL
                     TITITADADAPAAKSAVDYIKETWETALPGLTVEEKFVPFKQRLEDTKNQNFEVAVVL
                     WGGDYPKGSTFYGLFKSGSAYNYGKFTNADYDAAYNKALTTDALNTDAAADDYKAAEK
                     ALYDNALYNPLYFRSGEGLQNPSIKGLIRNSTGLNVDFTYAYKD"
     gene            32071..32985
                     /locus_tag="TVB59_000597"
     CDS             32071..32985
                     /locus_tag="TVB59_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1009529.1"
                     /translation="MIKYLLKRVAILVVTLWVVITLSFFLMQVMPGTPYNSPKLTDDM
                     IAMLNQQYGLDKPLWQQYLKYLFDILHGDFGTSYQSINQSVTTLISQRLGVSVHLGVQ
                     ALIVGISSGLAVGAVSARNKNNSIDAILSVISTLGISMPSFIIGLLLLDYLGFKWNLL
                     PLSGWGSFGQTILPTLALAIPVFAQVTRFFRSEMIETLSTDYIQLARAKGLTKRQVTR
                     RHAYRNSMIPVLTLVGPMAAGILTGSALIEQIFSIPGIGQQFVTSIPTKDYPVIMGTT
                     IVYALMLMVAILATDMIISIADPRVRLG"
     gene            32995..34026
                     /locus_tag="TVB59_000598"
     CDS             32995..34026
                     /locus_tag="TVB59_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004347296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1009530.1"
                     /translation="MLEETKSFKLVGAGSLATQEKIEKPALSFLQDAWRRLKHNKLAV
                     IAMGFLAVLLLFSIGSLFVVSTDDANSFNSKEVSIYRNLPPKLSSSLPFWNGTITYAG
                     NTEPNDAYADQGVPEDKAFLLGTDNLGRSIGKRITVGIRISLLIAIVATLIDLVIGVT
                     YGLVSGFVGGKTDMVMQRIIEIISSIPNLVIVTMLGLLLGNGVTSIIISIAIVGWTSM
                     ARQVRNLTLSYRERDFVLASRALGESNIRIAFKHVLPNISGIIIVQIMMTVPSAIMYE
                     SVLSAINLGVKPPTASIGSLITDAQESLQYYPYQVLLPAFALVLISLAFILLGDGLRD
                     AFDPKSSDE"
     gene            34038..35084
                     /locus_tag="TVB59_000599"
     CDS             34038..35084
                     /locus_tag="TVB59_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1009531.1"
                     /translation="MTNETILSVKNLHVDFKTYAGDVKAIRDISFELKKGETLAIVGE
                     SGSGKSVTTRTLMGLNAKNASISGNICFKGKQLNELKEEEWVKVRGNEIAMIFQDPMT
                     SLDPTMTIGMQIAEAIMIHQSIHKTEALKRALDLMRQVGIPNAEEHLKDYPHQWSGGM
                     RQRAVIAIALAANPDILIADEPTTALDVTIQAQILKLMKDIQSQTASSIIFITHDLGV
                     VAGMVDRVAVMYAGKIVEYGTVDEVFYHPQHPYTWGLLNSMPTTATAAGSLRSIPGTP
                     PDLLNPPKGDAFAARNEFALDIDHIKEPPMFKVSDSHYAATWLLDERAPKITPPFPIR
                     KRWAKWQEMEERKA"
     gene            35084..36019
                     /locus_tag="TVB59_000600"
     CDS             35084..36019
                     /locus_tag="TVB59_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1009532.1"
                     /translation="MTEARKKLIEVKNVSLTFNKGKKNEVKAIDRLSFDIYEGEVFGL
                     VGESGSGKTTVGRAILKLYDISDGEIIFNGENVSQLKGKKLHSFRKHAQMIFQDPQAS
                     LNGRMKIRDIVAEGLDIHGLTASKAEREARVQELLKLVGLNQNHLTRYPHEFSGGQRQ
                     RIGIARALAVKPTFIIADEPISALDVSIQAQVVSLMQQLQKKRGLTYLFIAHDLSMVK
                     YISDRIGVMHWGKMLEIGTSDEVYNHPIHPYTKSLISAIPEPDPEKERKRIAEVYDPS
                     QELDGQERQMHEITPGHFVLATQAEAEQYRAECGL"
     gene            complement(36648..38330)
                     /locus_tag="TVB59_000601"
     CDS             complement(36648..38330)
                     /locus_tag="TVB59_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEL1009533.1"
                     /translation="MTNISLRPNEVGVYAIGGLGEIGKNTYGIEYQDEIIIVDAGIKF
                     PEDDLLGIDYVIPDYSYIVDNLERVKALVITHGHEDHIGGIPFLLKQANVPIYAGPLA
                     LALIRGKLEEHGLLRDAVLYEINHNTELTFKHMSVTFFKTTHSIPEPLGIVIHTPQGK
                     VICTGDFKFDFTPVGDPADLHRMAALGKDGVLCLLSDSTNAEIPTFTNSEKVVGQSIM
                     NIIEGIHGRIIFASFASNIYRLQQAAEAAVKTGRKIAVFGRSMEKAIVNGIELGYIKV
                     PKGTFIEPNEIKHYHASEILIMCTGSQGESMAALARIANGTHRQVSLQPGDTVIFSSS
                     PIPGNTVSVNKLINTIQEAGVDVIHGKVNNIHTSGHGGQQEQKLMLSLIKPKYFMPVH
                     GEYRMQKVHAGLAVDIGIPEENIFIMENGDVLALTSDSARIAGHFNAQDIYVDGNGIG
                     DIGTAVLRDRRDLSEDGVVLAVATVDFETQMILAGPDILSRGFIYMRESGELIRESQR
                     VLFNAIRIALKNKDASIQSVNGAIVNALRPFLYEKTEREPIIIPMVLTPDSQ"
     gene            complement(38332..38562)
                     /locus_tag="TVB59_000602"
     CDS             complement(38332..38562)
                     /locus_tag="TVB59_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEL1009534.1"
                     /translation="MIYKVFYQETKERSPRRENTQALYLDIDAASELEGRIKARKMVE
                     EHTDYNVEFIELLSDKHLDYEKETGVFTLTEF"
     gene            38848..39546
                     /gene="tsaB"
                     /locus_tag="TVB59_000603"
     CDS             38848..39546
                     /gene="tsaB"
                     /locus_tag="TVB59_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEL1009535.1"
                     /translation="MKTLAFDTSNKALSVALLDDGTLLADLTINVKKNHSISLMPAID
                     FLMSSADLKPKDLDRIVVAEGPGSYTGLRVATATAKMLAYSLSIDLVGVSSLYALAAS
                     TCRENPDSLVVPLIDARRRHVYVGYYHHQKAVKQDKYASFDAVLAELVSCDHVIFVGE
                     VEGFAEDIRSALPEAKIKPSLPSAFEVGLLGSSLSADNVAAFVPQYLKRVEAEENWLK
                     THAAGDDSQYVKRV"
     gene            39549..39974
                     /gene="rimI"
                     /locus_tag="TVB59_000604"
     CDS             39549..39974
                     /gene="rimI"
                     /locus_tag="TVB59_000604"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEL1009536.1"
                     /translation="MMSIQEKAAAVYQVLKEVYGQSPWTLKQIVSDMQQEHVDYFTFY
                     HQETLLGFLAIQQLPGEMEITNLAVLPSYQGQGIASWLMGQLDGFEGVIFLEVRASNH
                     RAQQLYLKHGFEVVGQRSNYYHDPIEAALIMRREGKNDR"
     gene            39964..40980
                     /gene="tsaD"
                     /locus_tag="TVB59_000605"
     CDS             39964..40980
                     /gene="tsaD"
                     /locus_tag="TVB59_000605"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEL1009537.1"
                     /translation="MTDRYILAVESSCDETSVAILKNDNVLLTNIIASQVESHKRFGG
                     VVPEVASRHHVEVITTCFDDALKEAQLEASDLTAVAVTYGPGLVGALLVGLAAAKAFA
                     WANDLPLIPVNHMAGHLMAAREQGELEYPLMALLVSGGHTELVYVTEPGEYHIVGETR
                     DDAVGEAYDKVGRVMGLPYPAGREIDQLAHQGTDTYHFPRAMMKEDHLEFSFSGLKSA
                     FINLHHNAQQKGEELVLEDLCASFQAAVLDILLAKTKKALKQYPSKMLVVAGGVAANQ
                     GLRERLAEEITDIAVVIPPLRLCGDNAGMIALAAVVEYEKGHVAGLDLNAKPSLAFDS
                     FHQQ"
     gene            41002..42030
                     /locus_tag="TVB59_000606"
     CDS             41002..42030
                     /locus_tag="TVB59_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HEL1009538.1"
                     /translation="MFYLLLPPLICSVVFLAVYIKEPRTLWLGASFVTTLGVSLLCAM
                     IYIFSIEEKLQGVGILVLGVIGFLAIVWLMSSPFILLLFLSFNGIRLIKREGLSFRNL
                     LLIGSAVLLFVHPFISRLLLESIGDSKLLRIMYETSDLLILYLLLIVSVYTISSMLNT
                     FYFRKTKEDYIIVLGSGLNGDQVTPLLASRINKGIQIYQKNPGSKLIMSGGKGADELI
                     AEGEAMCRYAIQQGIKSEDILVENQSRNTRENILLSKQLIPSGASFCLVTNRYHLFRA
                     LLLAKELALPCRCYGAKTKLYFSMNAFIREIVGYLQLKKKQHLLAMLILTVGYIAIRV
                     VMIYMLHI"
     gene            complement(42425..42694)
                     /gene="rpsN"
                     /locus_tag="TVB59_000607"
     CDS             complement(42425..42694)
                     /gene="rpsN"
                     /locus_tag="TVB59_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001085658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEL1009539.1"
                     /translation="MAKKSKIAKYHKQLQLIEQYADLRRELKAKGDYEALRKLPRDSN
                     PNRLKNRDRIDGRPHAYMRKFGVSRINFRELAHKGQLPGITKASW"
     gene            complement(42888..44060)
                     /locus_tag="TVB59_000608"
     CDS             complement(42888..44060)
                     /locus_tag="TVB59_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEL1009540.1"
                     /translation="MILYDTIIIGGGPAGMMAAISSSYYGYKTLLLDKNKRLGKKLAG
                     TGGGRCNVTNSGSHDELIAGIPGNGRFLYSVFSQFDNHDIIAFFKENGVTLKEEDHGR
                     MFPTTDQSKTIINALEQKIKSLGAQVLISTEIVSVKKRNNLFYLKSVDQTFSCERLIV
                     ATGGKSYPSTGSTGFGYDIARHFNIAVTELEAAESPLLTDFPHKALQGISLADVTLSC
                     GKHQITHDLLFTHFGLSGPAALRLSSFVKGGDIAELDLLPQTSAAELLSYLAQHREKA
                     LKNALKTLMPERVADFLAKGYPEKGKQLTPTQTQELVNRIKQLPIPITGKISLAKSFV
                     TKGGIDLKEINPKTLESKKVAGLYFAGEVLDVNAHTGGFNITAALCSGWVAGSSQS"
     gene            44186..44716
                     /locus_tag="TVB59_000609"
     CDS             44186..44716
                     /locus_tag="TVB59_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HEL1009541.1"
                     /translation="MAIEKTVSELADILGVSRQAVNNRVKSLPEEDLDKNDKGVTVVK
                     RSGLVKLEEIYKKTIFDDEPISEETKQRELLEILVDEKNTEITRLYEQLKAKDSQLAA
                     KDEQMRIKDVQIAEKDKQLDQQQQLTAKAMADKETLKLELEEAKAEADQVRLQAEEIQ
                     SEMGPKKGFLNRLFGK"
     gene            44761..45348
                     /locus_tag="TVB59_000610"
     CDS             44761..45348
                     /locus_tag="TVB59_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEL1009542.1"
                     /translation="MKQLEAYIAFDMEFNTVNEVSHIIQLSAVKWHKHQEVDSFDSYV
                     YTAVPLQSFINGLTGITSDKIVSAPKVDEVLDAFKQFVGDTPLIGYNAQKSDLPILAA
                     NGLDLSAQYAVDVFDEAYERRSSDLNGIANLRLQTVADFLGIKGRGHNSLEDARMTAR
                     VYEAFVEFDDNKSYLNKQKEAIADNPFAALGGLFD"
     gene            45452..46174
                     /locus_tag="TVB59_000611"
     CDS             45452..46174
                     /locus_tag="TVB59_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEL1009543.1"
                     /translation="MSDIYSTGELAKAAGVTVRTVQYYDKRGILLPSQLTEGGRRIYT
                     ESDLERLKIICFLRDLDFSIEQIKRVLAEDNVMAVLDLLLVDHIQQLEQDLRTKKHQL
                     DTAVKLLSGIRCSSSHSIKNLSDMSLTMNNQKAWRRLQLKMFSNIALAILVHVMLVLL
                     TSYFHLSWLVWIEAPLWIIFFTLLIVYFRKQFEYLCPNCHTIFEPDFKEFALAGHTPR
                     TRRLTCPHCHQKSYCLELAKEK"
     gene            complement(46216..46515)
                     /locus_tag="TVB59_000612"
     CDS             complement(46216..46515)
                     /locus_tag="TVB59_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016503193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEL1009544.1"
                     /translation="MMNMQNMMKQAQKLQKQMEQKQADLAAMQFTGKSAQELVTATFT
                     GDKQLVSIDFKEAVVDPEDIETLQDMTAQAINAALAQIDEATKKTLGAFAGKLPF"
     gene            46913..47500
                     /locus_tag="TVB59_000613"
     CDS             46913..47500
                     /locus_tag="TVB59_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009545.1"
                     /translation="MTTTKQSKTTLAARYLKLGLTSAMFAGGAFLALGSAPAVSASTH
                     AGNDQPATQRLTDQEIYERAQKLDLPDYVRGSIYGILNQNSSVTYPKDIAGLEQSEAP
                     QPPAAPQLTDQDAQKLDLPDYVRGSIYGILNQNSSVTYPKDIAGLEQSEAPQPPAAPQ
                     LTDQDAQQLDLPDYVRGSIYGILNQNSSITYPRDY"
     gene            47639..>48181
                     /locus_tag="TVB59_000614"
     CDS             47639..>48181
                     /locus_tag="TVB59_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1009546.1"
                     /translation="MTYKILLVDDELEIIDINERYLQQAGYRVTTASDGSQALELFHK
                     DQYDLIISDVMMPNMDGYDFIGEVLLEKPDQPFLFITAKTSEPDKIYSLSLGADDFIS
                     KPFSPRELVLRVKNILNRIYGKANQADSLVIGDLVMDHSTRRVTVANQDLNLTNKAFD
                     LLWILANHLNHVFSKTELYER"
BASE COUNT        13643 a         9419 c        11267 g        13852 t
ORIGIN      
        1 aaaggaaaat agagcttgac aggggagttt gattattata gaataatagg gtatgtttag
       61 taactgatat cacaaatagc cggctaaacg aatacgaaaa tctatgagga ggtattcact
      121 gtgaaacgta cttatcaacc aagtaagatc cgtcgtcagc gcaagcatgg cttccgtcac
      181 cgtatgtcaa ctaaaaacgg ccgtcgtgtg cttgctagcc gtcgtcgcaa aggacgcaaa
      241 gtattgtcag cataattgca gaatacatca attaaacaaa tcaggagtgc tcgaggctct
      301 tggtttttta attgttcaaa agtgctaaga gcagcttgat gagtgcttat aaagcaggag
      361 ataggagcca aaaagaggct gcttttttaa ttgctcttcc tgaatacgtt ttcaaaaata
      421 acggaaatag ggctaaaaat gaaagtagtt tctaaaacca gaggaagtat tgaaaacgct
      481 ttaatatctg ctacaataaa gatgtgaacg ttctctaaaa ttaataaaag gagtagaaag
      541 catgcttgaa aaaccaagca aggcagagct actggcagct ctgaaggacg ggctgatcgt
      601 ttcctgtcaa gctctgccgg gcgagcctct ctattcagag gcaggaggta tcatgcctct
      661 gatggtaaag gcagcagagg aagcaggagc agtagggata cgagccaatg gtgttcgaga
      721 tattaaggaa atccaagcgg tgacggatct gccaatcata gggatcatca aaaaggagta
      781 tcctccgcaa gcgcccttta tcacgccaac catggcagag gtagatgcct tagcggcctt
      841 aggtgtagcg gtgatagcct tggattgtac gcaaagggag cgtcatgatg gcttagcgat
      901 agtggatttt attcgagcga taagggagaa gtacccagag cagctgttta tggcagacat
      961 cagtacgctt gaatagggtc tagcagccta tgaggctggt atagattttg tagggacgac
     1021 cttatcaggg tatacgccct atagtcgtca ggggacaggt ccggatatgg agctgataag
     1081 tgccttgtgt gatgcagggg tatcagtgat agctgagggc aagattcata gtccagagga
     1141 ggccagggct gttcaggcct tgggagtagc tggtattgtg gttggtggtg ctattaccag
     1201 accaaaggaa attgcagagc gctttgtggc ggctttgaca tcgtcattgt ctataaaaaa
     1261 taattaatat aaaggagaat ttacaatgaa aatgaagaaa ttagcttcat ttgtgatgct
     1321 tggagcatct gttttagggt tagcagcctg tggcagtagc agcaaggagg ctgacaaatc
     1381 agattcagct gctaagacag agatcacctg gtgggccttt ccaaccttca ctcaagaaaa
     1441 ggctgatgat agcgtaggaa cctacgaaaa gaaaattatt gcagcctttg aaaaggccaa
     1501 tccagatatt aaggtcaagc tagaaaccat tgatttcacc tctggtccag aaaaaatcac
     1561 tactgcgatt gaggcaggta cagcaccaga tgtgctcttt gatgctccag gtcgtatcat
     1621 tgagtatggt aaaaacggta aattagctga cttaaatgac ctgtttactg atgagtttat
     1681 caaggacgtc aacaacgata acattatcca agcctctaaa gcaggagata cagcttatat
     1741 gtatcctatc agctcagcgc cgttttatat ggccttaaat aaaaaaatgc tcaaggacgc
     1801 tggtgttctt gaccttgtca aagagggctg gacaaccgat gattttgaaa aggtcttaaa
     1861 agccttaaag gataagggct acaatcctgg gtcattcttt gccaatggtc agggtggtga
     1921 ccaaggtcct cgtgccttct ttgccaacct ctatagcagc cgcatcacaa atgacgatgt
     1981 gactaagtac accactgatg atgctaattc tgtcaagagc atggagaaaa tcgcaagctg
     2041 gattaaggat ggccttctaa tgaatggctc tcaatatgat ggctcagctg atattcaaaa
     2101 ctttgctaat ggtcaaacct catttacaat cctatggtca ccagcgcaag caggaacaca
     2161 ggctaagctg ttggaagcaa gtaaggttga ttatgttgag gttccattcc catcagagga
     2221 cggcaagcct gaattagaat acctagtgaa cggctttgca gtgttcaaca acaaggacga
     2281 caaaaagatt gaagcttcta agaaatttat ccagtttatc gcagatgaca aagaatgggg
     2341 tccaaaaaat gtggttcgta caggtgcatt ccctgtaaga agctcttatg gtaatctcta
     2401 tgatgatgaa cgcatggcaa tggtttctaa gtggacacaa tactattcac catactacaa
     2461 cactattgat ggctttgctg agatgagaac actatggttc ccaatggttc aggcagtatc
     2521 aaatggagat gaaaagcctg cagcagccct caaagcattc actgaaaaag caaataaaac
     2581 catcgaaaaa gcacaatagt gtgagataaa agtggctcct tttcaatgca catgtccaat
     2641 ggtcactggt aaggagcctt tccttttagg aagattaata gaaaaagagg tatctttgag
     2701 tgaacgtcaa taagttaaaa atgagagaga cactcgtttc atatgctttt ttggccccgg
     2761 tcttggtttt ctttgtggta tttgttttag taccaatgat tatgggcttt gttactagct
     2821 tttttaatta tacgatgaca gactttacct ttgtcgggct tgataactat gtgagaatgt
     2881 ttcaggatcc tgtgtttata aagtctttga ttaataccct tattattgta gttggttcag
     2941 taccaattgt tgttttcttt tcattatttg tagcgacaaa aacctacaat aagcatgtga
     3001 tttcacgttc gttttaccgg gcggttttct tcctgccagt tgtgacaggt agtgttgcgg
     3061 taacagttgt ttggaaatgg atctatgatc ctatgtcagg tattttgaac tatgtgctaa
     3121 agtatgggca tgttattgag caaaatatta gctggcttgg ggacaagcat tgggccttgc
     3181 tggctattat tgtgatttta ttaacaacct ctgttgggca gcctattatt ctttatattg
     3241 ctgcgatggg aaatattgac aattccttag tggaggcagc tcgtgttgac ggtgcgactg
     3301 aattgcaggt cttttggaaa ataaaatggc caagtctatt gccaaccact ctctatatca
     3361 cggtcatcac aacgatcaat tctttccaat gctttgcctt gattcagctg ttgacctctg
     3421 gtggtccaaa ctattcaacc agcaccctga tgtactatct ttacgaaaaa gccttcaagc
     3481 tatcggaata cggctatgct aacacgatgg gggttttctt ggctatcttg atttcactga
     3541 tcagctttgc ccaattcaaa ttcttgggta atgatgtgga atattaaaag gagcttgaca
     3601 tgaggaaaaa gaaattaaca gcatcagata tcctaacaac agccattcta tgtttattaa
     3661 caatattatt tattttcccc ttttattgga tcatgacagg agcctttaaa tcccagccgg
     3721 atactattgt tgtcccacca caatggtggc caaaggcacc tactgttgaa aattttaagg
     3781 ccttgattat tcaaaatccg gctcttaaat ggctctggaa cagtatctat atttctgttg
     3841 ccaccatgct tttggtttgt ggcacctctt ccttggcagg ctatgcttta gcaaaaaaac
     3901 ggttttatgg gcaacgtttg ttgttttcaa tctttattgc tgctatggct ctgcctaagc
     3961 aggtcgtctt ggtgccattg gttcgtattg tgaattttat gggcatccac gatacgctag
     4021 cagcagttat tttgcctttg gtgggctggc cttttggggt attcctgatg aagcaatttt
     4081 cagaaaacat accaacagag ctgctggagt ctgccaaaat tgatggctgt ggtgagatta
     4141 gaaccttctt taacgttgct tttccaatca ttaagccagg ttttgctgcc ttagcgatct
     4201 ttacctttat taatacctgg aatgactact ttatgcagct agtaatgcta acatcaagag
     4261 atcatttgac aatatccttg ggggtagcca ctatgcaggc tgagatggca acaaactatg
     4321 gtttgatcat ggctggtgca gctcttgccg cagttccgat tgttacagtc tttcttgtgt
     4381 tccaaaaatc ctttacccaa ggtatcacca tgggagctgt caaaggttag aaaggtcagg
     4441 agattatgct ctatgatgtc ttggaaaaca ttcgtcgcta caagggtatc catcggcatt
     4501 tagatgtggc cattgacttt ttattgacaa gagatttaag gtcactcaca gatggcaagc
     4561 atgtgatttt agaggataag gtggttctct ttattcagca taattgtctc aataaagagg
     4621 ataatgcctt gtttgaatac cataagcgct atgccgattt gcatctacta gtcgagggga
     4681 atgagcgagt acgctatggc ttaggctaca agcaggaggc tgttagcttt gatgaggcat
     4741 cagacatcgg ctttgtgacc tgcgagagga cttatgactt ggacttggga aatgattgtt
     4801 tttgctattt ctttcccaat gaagctcatc agcctaatgg ctttaacgac gatggtgatg
     4861 cggtcacaaa atgcttgatt aaggtgttga tggaagatta actagaaagg atagggagta
     4921 atgatatgag cagcaaaaaa agaaagctaa tgcagtccat ttttagcttg gatagcaaat
     4981 ggctgagggc tagtgctact atctttgacc ttatcgtgct caatttgctt tttgtgctgt
     5041 cttgcttgcc tgtggtaacg attggcattg ccaaaatggc cttgtatgct agtctgcgag
     5101 attaccggca aggggatatc ggctctgttg taggcgtcta cggctcttat ctacggcggt
     5161 ttgccaagag aggccttcaa ttagggatcc tagaagtgct cttgacgagc tttatcttgg
     5221 ttgaccttta tctcattcag gctcaggtgt cgcttttctt tcaactattt aagattagct
     5281 gtatagcgat attatttgtg gctattatgg tctttttgta tgcttatcct ttagctatgc
     5341 gatatgattt gcctcttatg tcattatttc agcgaagctt tatcttgctt agtcttttct
     5401 tcccctttag ctttgctttt ttagctgtta tgctgctagt ggtctttttg ctgcagctat
     5461 ctccgctaag tctattagga gggctgtcgc ttttagccat tattggcatt agcagcctaa
     5521 cctatcctta tgtcgtcatt atggaaaacc ttcttcaaaa ggtacaactt tattaaaaat
     5581 aagatttaga aaaagagtgt cattatgaaa actttaacca aatatcaagg gattatccct
     5641 gccttttatg cctgctacga tgctgagggc aacatcagtc cagagcgtgt tcgtgctttg
     5701 acacaatatt atattgataa gggtgtccaa gggctttatg tcaatggctc atcaggcgag
     5761 tgcatttacc aaagcgttgc agaccgtaag ttggtcttag agcatgtgat ggcagtagcc
     5821 aagggcaagc taaccattat caatcacgtt gcctgcaaca ataccaagga cagcattgag
     5881 ctggctcagc atgctgaggc cttgggggtt gacgctattg cagcgattcc accgatttat
     5941 ttccgtttgc cagagcatgc tgtggctgct tactggaatg caatttcagc tgctgctcca
     6001 aatactgatt ttgtgattta caatattcct caattggctg gtattgcctt gaccccaagc
     6061 ctctatcagg aaatgctcaa aaatgagcgt gtcataggtg tcaaaaactc ctccatgcct
     6121 gttcaggata ttcaaacatt ttgtgctatc ggaggtgatg atcaccttgt ctttaatgga
     6181 ccggacgagc aatttttagg gggtcgtctc atgggggcct ccgctggaat tggcggtacc
     6241 tatggagcga tgccagagct tttcttacgc ttaaatcaat tgatcaagga caaggaccta
     6301 gagactgcta aggccttgca gtacgctatc aatgatatta ttgggttatt ggtttctgcc
     6361 catggcaata tgtatggtgt tatcaaggaa gtgctgcgca ttaatgagag gctggatatt
     6421 ggctctgttc gttctccttt gccagagtta accgaaaatg atttggtgat ctgtcagcag
     6481 gctgcagcct tgattaagca gaccaaggaa caattttgct cttaaaatga ggtgatcaaa
     6541 tgaagcgtta tcttgctatt gatattggcg gtacagccat caaatatggc cttatgacag
     6601 agacagcaga catactggaa aagcatgaaa tcgccactga ggctcataag ggcggtcctg
     6661 ctattttaga caaggtcaag gacctggttg cgacctatca ggaggctgga ctagctggtg
     6721 ttgcgatttc ttcagctggc atggtggatc ctgataaggg cgaaatcttt tacgcagggc
     6781 cacaaattcc gaactacgca ggcacgcagt ttaaaagggt gattgaagaa acctttggta
     6841 ttccctgtga tgttgaaaat gatgtcaatt gtgccggtct agcagaggct atttctggca
     6901 gtgctaagga ttgccctgta gccctttgct taaccatcgg tacaggaatt ggcggctgcc
     6961 tgctgattga ttcgcaggtt tttcatggca gcagctactc tgcctgtgag gtaggctata
     7021 tccatttgcc ggacggtgcg tttcaggatt tggcctccac aacagctctt gttagagatg
     7081 ttgctagacg tcatggagat gctgttagcg attggaatgg tcgtcgtatt tttgaagagg
     7141 ctaaggcagg taaccaccat tgtatagcag ccattgacca gttagttgac tatctagctc
     7201 aagggcttgc caatatctgc tatgttgcta atccaaatgc tattgtctta ggcggtggca
     7261 ttatggctca aaaggactat ttgcaggata aaatcctagc tgccctcaat aattatctgg
     7321 tacctagcat cgcagaaaaa acccagcttc gatttgccag ccatgaaaac aatgctggta
     7381 tgattggggc ttactaccat ttcaagcata aggagcaagt ctaatgatag aaaccatgtc
     7441 acttgaagag atgatgtcct acagggggcg tcacgaggtg cccaaggatt ttgatcattt
     7501 ttgggagacc tgtatcaagg aaaatcaagc tgcctcttat cagcttgatc aaaaggattt
     7561 tggccttgat tttgctgatt gctatgagtt gcgcttcaaa gggagtaatg gctcaacgat
     7621 ctatgccaaa tgtgtctttc caaaagccaa gcagctagtc ccagttgtct tttattttca
     7681 tggctaccag ggtcagtaca cagctagcta gggtcattga ggtgcttttt tgtgatgcta
     7741 tttatctgaa ggattgataa tcgtctcttg gaaaattttt gttttgcctt ccttgttgat
     7801 ttctaaaaaa taagcgtaga taatatccgt tacaaagagc attggaaatt gtggggagat
     7861 acgattgcca tagttaaggt gacgagcagt agcgatatgc acaatttcgt caagctggta
     7921 agggatttca tcggtctggg ttgtgagcag cactgtcttg gcaccgcgtg tcccagcggt
     7981 ctgcaaagcc tctaagacgg acgctgtttg agcagagagc gaaaaaccaa taaccaagca
     8041 tttgtctgta atgctgctgt taacccaggt gaagctatca gtgtcatcta aggcctcgca
     8101 aataacacca agtcgcatca gacggagctt gaattctttg gcggcaagag ctgagctgcc
     8161 cttaccgtaa aaataaatcc gctcagcatt ttcaatccat tgcgcaatgt cttgtagctg
     8221 cttttcattg atcagctcgg tagccttttc gatcaattca cggtagttca taaggacctt
     8281 tttagtgttg taattttgca ggttgggtgc cttttgatcc attgcctcgc gacttttttg
     8341 gcattcaaag ataaattcgc gataaccggt aaagccacat tttttggcaa agcgtgtcaa
     8401 ggctgcctgt gagacatgaa gccttttaat catgtctgaa gctgttagct cttcgacctt
     8461 taggtctgtt tccataaaaa attgagcgat gcttttttct aagctcgtca tgctgtctag
     8521 tgcagcttcc attttgctga ttaaacggtg attgtgtatc atatgaactc cctgatgtaa
     8581 ggctgtctat tataatagta tatcataaaa aggaaaaaga taaagaatac agataatata
     8641 ataatataga gctgatatta cagttatgtc aaggctgact gtttgagtaa accaagagct
     8701 atgctaagaa tgaagtagct gatgagatat ggtataataa tcaagcaggt atccctttta
     8761 gggcaataca agaaagagga atgactaaga atgatagaaa tttttgatac ccatacgcat
     8821 ttgaatgtgg atcattttag tggtaaagag gaagaggaat tagcacttgc taaggagttt
     8881 ggggttagct accataatgt cgttggcttt gatcaggaga ctattgatca agcccttacc
     8941 ttagctgatg cttataggga ggtctatgca acgattggct ggcacccgac tgaggctggc
     9001 tcttacacac aggcggttga agatagtctg attgcttgct tgaagcaccc aaaggttgtt
     9061 gccttaggag agattggctt ggattactat tggatggagg accccaagga ggtacagata
     9121 gaggtcttta agcggcagct acagcttgct aaggaccatg acctcccctt tgtggtgcat
     9181 acgcgtgatg cccttgagga tacctatcag gtcttaaagg aggctggagt gggtcctaga
     9241 ggtggtatca tgcattctta ctcaggatca cttgagatgg ctcaacgatt tgtagatctg
     9301 ggtatgctga tttccttttc aggggttgtc acctttaaaa aggcggttga tgttcaggaa
     9361 gcagcaagac acctgccgct ggataagctc ttggtggaaa cagatgcccc ctacctcgcc
     9421 ccagtaccaa agagaggacg tgaaaaccat accgcctata cgcgttatgt tgttgagaaa
     9481 atcgcggagc tacgtggttt atcagtagaa gagatagctg cagcaacgac tgccaatgca
     9541 aagagggtgt ttagaattga ctgagaagct taaaattcaa gaggttattg tggtagaggg
     9601 gaaggacgat accgctaatt tacagcgctt ctatgatgtc gatacctatg aaacaaaggg
     9661 ctctgccatc actgatgagg acttagaacg cattgatcgg cttaacaagc tgcgtggtgt
     9721 gattgtcttt acggatccag attatcatgg cgagaggatt cgcaaactga ttatgagagc
     9781 tgtcccaaca gctcgtcatg cctttttacg tcgacatgag gctaagccaa ggtccaaaag
     9841 taagggacgt tccttaggtg tggagcacgc tagctttgag gacctgcaaa aggctctgtc
     9901 tcaggttacc cagtcttttg atgacgagag ttattttgat attagtcaga cagatttgat
     9961 tcgtctaggg cttttattgg cagctgatag ccgcaagcgc agagagtatc taggagaagt
    10021 ccttcgtatc ggctattcca acggaaagca gctcctaaag cgcctaaagc tatttggcat
    10081 taccctatca gaggttgagg acgtgatgac ctcctatcag actgagcaat agatggcgct
    10141 agaaaggctg attggatcaa acaaaagagc cctgagactt cttgttctgg ctccaaaaaa
    10201 ttagataaga aatggtaaca aggattgaat tctgtattgg gcaggagtca gtccttttaa
    10261 ctttcttaga taagcattct ctgttctaag acgttcattc tccttgaagt tgctctagtt
    10321 ctccagatgt tctttgattg atgtcctctc ttgcttggtt tccctcttgt tttatcaaga
    10381 atagtataac cattttcatc tctttttttg ctgtggctct gataaataat agaaatatgc
    10441 tacaatagat ataaaacaat gaataggaca tcaacatgag aattgcagat tacagtgtaa
    10501 ccaagtctat ccttgatcgc tatggtttta cctttaaaaa atcatttggt caaaatttct
    10561 tgacggatac taatatttta cagaagattg ttgatacggc tgagattgac aagtcagtca
    10621 acgtcattga gattggtcct ggtatcgggg ctttgaccga atttttggca gaaagggctg
    10681 cagaggtcat ggcctttgag attgatgagc gcttggtgcc aatactggct gatacgcttc
    10741 gtgattttga caatgttcag gtggttaatc aggatatttt aaaggcagat ttacagaccc
    10801 agctaaagca atttagcaat ccggaccttc ctatcaaggt ggtagccaat ttgccctatt
    10861 acatcactac acccattttg atgcacctga ttgaaagtaa gattcccttc caagaatttg
    10921 tcgtcatgat gcagcgcgag gtggcagatc ggatttcagc tgagcccaat accaaggcct
    10981 atggctcttt gtctatagca gtccagtatt atatgaccgc taagatagcc tttgttgttc
    11041 ctaggactgt ttttgtgcca gcaccaaatg tggattcggc aattctgaag atgactcgtc
    11101 gtgaccagcc cttgattgag gttcaagatg aggatttctt ttttagggtg tcacgagtag
    11161 gctttgtgca tcgcagaaag acgctttgga ataacttggt tagccatttt ggcaaggctg
    11221 aggacacaaa ggcaaggctt gagcagggac tagctctagc tggaatcaag ccttctatcc
    11281 gaggagaagc gctgtctatt caagattttg gacggttagc tgatgcccta aagcaagtag
    11341 gcttctagtg ccttagttat gattgtagct tgtcacagca atcctgctgt ggctttttta
    11401 gatagtggtg ggttcatctt atctttggtg aaacttgggc taaactgctg aattcgaatg
    11461 atttttctga tataatggca ttattctagg ataaaaaaag gagttcattt gcaaggcaaa
    11521 atcattaagg ctctggctgg cttttactat gttgagtcag aggggcaggt ttatcaaacg
    11581 cgggcgcgtg gcaattttag aaagcgtggt caaacaccct atgtaggaga tttagtagaa
    11641 ttttctgctg aggacaattc agagggctat attttagcta ttgctgagcg gaaaaatagt
    11701 ctggtgcgtc ctcccattgt caatattgat caagcagctg tcattatgtc agccaaggag
    11761 cctgatttta ataccaacct tttagatcgc tttctcattt tacttgagca caaggccatc
    11821 caccctatta tttacatttc aaaaatagac ctgcttgagc agccagagag tatcgaagcc
    11881 attggtcagc attatcgtgc gattggctat gattttgtga cgagcttatc acatctgctg
    11941 ccattattag ctggtaagac aacagtattt atggggcaga caggagttgg aaagtccact
    12001 ttgctaaacc gtatcgcacc agagctagct cttgaaacgg gtgatatttc agacagtctg
    12061 ggacgaggac gccacaccac tagagctgtt agcttttatg acgcttataa tggcaaaatc
    12121 gcagacaccc ccggcttttc gtccttggac tatggcattg ataatgctga ggatctcaac
    12181 gaagcctttc cagagcttag acgccttagc catagctgta aatttcgctc ctgtacccat
    12241 actcatgagc ccaagtgtgc ggttaaggaa gccttgggaa atggtgagct ctggtctgtt
    12301 cgctatcaga attaccttca atttctgagt gaaatcgaaa accgtcgaga aacatatcaa
    12361 aaagttagta aaagaaagta ggtttaacta tgtcatctct gaaaattgcg ccatctattt
    12421 tagcagccga ttatgcttgc tttgctgctg agctggctcg tattgaaaaa acagatgctg
    12481 aatacgttca tattgatatc atggacggtc agtttgtgcc aaatatcagc tttggagcag
    12541 atgttgttgc tagcatgcgc aagcacagca agctagtctt tgattgccac ttgatggttg
    12601 tgaatcctga gagatatgtt gaggcctttg ctcaggcagg agctgatatc atgaccattc
    12661 atgtggagag cactcttcat agtcatggcg ccttgcaaaa gatcagggct gccggcatga
    12721 aggctggtgt ggtcattaat cctgggacac ctgtctctgc ggttgagcct ttattaagct
    12781 tggtggatca ggtgctgatc atgactgtta acccaggctt tggaggacag gcctttattc
    12841 cggaatgtct ggaaaaggtt gcagctattg ctaaaatgag agatgaaaga ggcttgagct
    12901 ttgatattga ggttgacggt ggtgttgatg ataaaaccat tcgtgcttgc tatcaagcag
    12961 gagctaatgt ttttgtggct ggctcctatc tgtttaaggc agcggatttg gcagctcaag
    13021 tgcaaacatt gagggcggcc cttaatggtt aaggtagccc tctttgcagg tggggatttg
    13081 tcctatttta cctgtgattt tgattatttt gttggaattg atagaggaag tctatttttg
    13141 ttagaaaatg ggcttccttt gaatatggct gtaggcgatt ttgattcaat tccccaagta
    13201 gcctttgagg ttgtcaagga gcaagcagag cttcttgttc aggctagtcc tgaaaaaaat
    13261 gatacggaca ctgaattagc tctcaaagag gtatttaccc gttttccaga ggcagaggtt
    13321 acgatctttg gtgcttttgg cggtagacta gaccacttgt tatccaatgt ctttttacca
    13381 gcggatccag agcttgcacc gtttatggca caaatttgcc tgcgggatca gcaaaatgcc
    13441 attagctatc gatcctctgg ctggcagacg attaggcagg ataaggacat gacttatgtg
    13501 gcctttatgg ctgatggtga tgctgacttg accattacag gtgccaaatt tgatttgacg
    13561 acgtccaatt tctttaagaa aaaggtatac gctagcaacg agttcattga tcagcctatt
    13621 aaggttcatg tgccaaaggg ctatttaatt attattcaga gcaaagatag gagttagtat
    13681 ggaccttatt cttttcgtgt tagtgcttgt gttgatagga cttgctgcct attcatttgt
    13741 tagcataaag catttgcaga gcagattaga aaaagcctta gacgataatg ctgataatct
    13801 atcagatcag ctaacctacc agctggatat ggcaaataag agtcagctgc tagagctatc
    13861 aacagtgatg aatcgtcagc aaaatgagct ttttcagcag ctgatggtta ttcgtgatac
    13921 gctgcatcag ggcttggctg aaaatcgcga ccgctcagac cagcgtttgg aaacgatgac
    13981 tcaaagcctt agccaagctg tcaagaacct acaggattct aatgaaaagc gactggagga
    14041 aatgcgccat acagtcgaag aaaagctaga aaagacattg aagaatcgat tgcaaacctc
    14101 ctttgaggcc gtttcaaagc agctagaaag cgtcaatcag ggtctaggag aaatgcggac
    14161 cgtagccaaa gatgttggta ccctaaacaa ggtcctatcc aataccaaaa ccagaggaat
    14221 cctaggtgag ctccagcttg gtcagattgt tgaggacatc atgacagcta accagtatga
    14281 aagagagttt gccacagttt ctggctcaag cgatcgtgtc gaatacgcta tcaagctacc
    14341 tggaaatggg caaggagact atatttacct acctattgac tccaagtttc ccttggagga
    14401 ttattacagg ctggaggacg cctacgaggc tggtgataga gctgctattg agactagccg
    14461 aaaggctctt cttgcggcga ttaaacgttt tgctaagagt attcatagta aatacctgaa
    14521 tccacctgaa acaaccaatt ttgggattat gtttttacca accgaggggc tctactcgga
    14581 ggtggtgcgc aatccggctt tctttgatag ccttcgtcgc gaggaaaata ttgttgtagc
    14641 aggcccatca accttatcag ccctgcttaa ttccttatct gttggcttta aaacccttaa
    14701 cctgcaaaaa aacgcagacg atattagcaa gattttaggc aatgtcaaat tagaatttga
    14761 aaaatttggc ggcctgcttg ctaaggcgca aaagcagctc aacactgcta accataccct
    14821 agaccagctg atgtcaacca gaaccaaagc gattgttcgt gctctggcta ctgtcgaagg
    14881 ctaccaagac cagtcaaccc aatccttatt acatataccc ttattagaag aggcagacga
    14941 tgaagattaa ccaaatgaaa aaagaccagc cttttgaagg cttttacctg ataaaatcag
    15001 cagaagtcag aaaaacaagg gctggcaagg attttattgc ttttaccttt caagatgata
    15061 ctggtgagat ttcaggtaat ttgtgggacg cccagcccta taatgttgag gaatttgtcg
    15121 caggtaagat tgtctttatg aaaggccgtc gtgaggtcta taatggcact cctcaggtta
    15181 accagattac cttaagaaat atccggcctg gggagcctaa tgacccaaag gaatttaaag
    15241 aaaaggcacc tgtcagtgtt actgaggttc gtgactacct agatcagatg ctctttaaga
    15301 tcgaaaatgc gacctggcag aggattgtca gagcgcttta ccgcaaatat gataaggagt
    15361 ttttcactta tccagcagcc aaaaccaatc accatgcctt tgaatcaggc ttggcctatc
    15421 atacagcaac gatggttaga ctagcagata gcattggaga tatttatcca gagctaaata
    15481 aaagcctgtt atttgcaggc attatgctgc atgacctagc caaggtactt gagctgacag
    15541 gcccagacaa taccgaatat actatccgag gcaatctgat aggacatatc gccctcatca
    15601 acgaagagat tacaaagacc atcacagagc tgaacattga tgacaacaaa gaagaggtca
    15661 ccgttttacg ccatgtaatc ttaagtcatc atggccaatt agaatacggc agccctgttc
    15721 gtccgcgcat tatggaggca gagattattc acatgattga caacattgac gccaatatga
    15781 tgatgatgtc aacagctctc agtcgtattg gcgagggaga aatgaccaat cgtattttcg
    15841 ctatggataa ccgatccttt tataaaccta aatattagca aggatcataa taaaaaacga
    15901 acattttgca gttgaatgtt cgttttttcg ttatgttatg atataatagt agagaatata
    15961 taaataatgg ggaacatatg aaattaagac gaagtgaacg catggttgtg atatctaatt
    16021 acctgattaa caacccttat aagctaacaa gtttaaatac ctttgccaca aaatatgagg
    16081 cagccaaatc atctatttca gaagatattg ccattatcaa aaaagccttt gaagaatcta
    16141 atattggaga gattgacact ctaacagggg caagtggagg tgtcattttt acgccaagca
    16201 tttcagaggc agaggctcgc tcaatcgtag aagagctgtg tcagcggctt tcagaaagta
    16261 accgcatttt acctggtggc tatatctatc tgtctgattt attaagcaca ccaaagctct
    16321 tgcagaatat cggtcgcatt atcgctaatg cttttaaggg gcaaaaaatt gacgcggtga
    16381 tgacagttgc aactaagggg gttcccttgg ctaatgcggt tgcaaatatt ctgaatgtac
    16441 cctttgtgat tgtcaggcgc gacttaaaaa tcacagaagg ttcaaccgtc tcagtcaact
    16501 acgctagtgc ctcaagttat cgtattgaaa aaatgttttt atcaaagcga agcttaaagc
    16561 caaacagtcg agtcttgatt gttgatgatt ttttaaaggg tggtggtaca atcacaggca
    16621 tgatgagcct gttaacggag tttgatagta cattggtggg tgtagctgtt tttgcagaaa
    16681 atgcacaatc agagcgcgaa caaatgtcct tcaagtcact attaaaggtc tccgaaattg
    16741 atgtcaaaaa taatagggtc gttgttgaag taggaaatat tttcgataaa taaatcgaac
    16801 gtaggtggaa aaataaaagg ggattaatca tggagcaaga aaactcaaga acaaagcatg
    16861 ttaaaagtac cattgctttg acatcaacca ttgccctatt agggacaagc gttggtgtat
    16921 cacatcaggt aaaggcagac gatgctaagt caggcgatgc caatacaagc aataccagcg
    16981 aagctacgct agctaagcca gaaacgcttg aggaggcagt ccttgcggta aaggctacag
    17041 aagaaacact cagtgagcgt aaaaaagaat tagctgagac taatacaaat atcgcggaaa
    17101 cagagggcga aatcgcaaac ctagaagcaa ctaaaaaaga acagatagct gagcttgcca
    17161 aggctgagga gctacttgag acttactcgt ccatgagtga ggaagaccta gccaagtcaa
    17221 ttgaaaagca tgagacagag ctagagacaa ttaacacaga actagagaag gcgactactg
    17281 agagtcaagc tcaggcagag gcagtggcta agcagcaaga aacgatcgca gcagaggcta
    17341 caaaggccga ccagctagct acccagctaa cagcagcaga gcaaaaggtc tcagacctta
    17401 acacgatgat tagccagccg gaagctattg tctcagaagc tcaagctgca aaagaagagg
    17461 tcaagcgcat ttctgatgac ctagcaaagg ctacagcaaa tctagctact gttaaggaga
    17521 cagtccacag ccagctaacc tcagacctag cagccaacaa ggcagccctg gcagctaaag
    17581 aggcagagct gcaaaggctt caaaatggag ttgccactgc ccaattgaac gttgctggca
    17641 gcaataaatt aattcttcca aaagactacc caattgagga gattaaaaag ctagcagcca
    17701 gtggttatat cggaacagca gcatataatc aatattatca ggcagttaag gatacaatga
    17761 ttgcaaaggc agagccgggt gctgccatga atcagtatgt tgatattcct gaggacctca
    17821 atcgtgttgt tgaccctgac aacctatcac aagaggttca aaatgagcta gctcagtttg
    17881 cagctcaaat gattaatgat gtccgcaagc agctaggact tgtccctgta acagtaacag
    17941 tcggctcaca ggagtttgct cgcctgctaa ccaagagcta caaggaaaca catcaaaata
    18001 ctcgaccttc ctttgtctat ggacaagtag atgcttcagg tcatcgcggt gtaggtccgc
    18061 atgatcaaac gattattgaa gaatctgctg taaaggtagg acttcgtcaa aaagatgaca
    18121 acatgtacga aaaccttggt gcctttaacg aggttcacac tgtcaacggt atcaagcgcg
    18181 gcatctatga cagcattaag tatatgctgt ttacagatca cctgcatggg aacacctatg
    18241 gtcatgctgt taacttcctg cgtgttgata agactgaccc taatgcacct gtttacctag
    18301 gattttcaac aagtaatgtt gagtccttaa atgagcattt tgtgattttc ccagagtcag
    18361 atattgtgga cgctactcgt tttagcacga ctgaaattcc aaaatcaggt caggtgattg
    18421 atcgctcagc aagcatacag gcattgacaa atgatattgc ttcgatcaag ggcaagattg
    18481 cgtctcttga aagcagatta gctgatcctt cctcagaagc tgaggtcaca gctgcgcagg
    18541 caaaaatcag tcagctgcaa catcagctag aagcagccca agccaaatct cataaattgg
    18601 atcaacaggt tgagcaattg gccaatacaa aagattctct acgcacacag ttgcttgctg
    18661 ccaaagaaga gcaggcacaa ttgaaggcta atctagataa ggccttggcc ttgctagcgt
    18721 cttcaaaggc tacgcttcat aagcttgaag cagctatgga agaggctaag gcaagagtag
    18781 ccggcttagc tagtcagaag gctcagcttg aggatctgct agcctttgag aaaaatccta
    18841 atcggatcga gcttgcacag gaaaaggtag ccgcagccaa aaaggcttta gctgatacag
    18901 aggataagct cttagctgct caggccagcc tgtctgattt gcaggctcaa agagcaagac
    18961 tccagctttc tattgcgaca attgaacaac aattagtact attgaagaat ttagtccaag
    19021 aaaagcaaag gctcagactt gaggctgaaa ggctaaatag catgtcagaa acaagacagc
    19081 ttctcaatca gctagcgccg caggctgcaa aagcaggtgt cggctcagaa ttggttgcta
    19141 caggtcttct tgtctccaag gttgcctcag ctatcgctaa gcaatcaccg acaagccatt
    19201 cctatggagc aggagcagca tcacatgcag ctgttgatga caacacacag cgtgctgttc
    19261 aggctggtat ggtcatgctg gcagctgccg gcttagcaac ggttaagctc aaaaaaggca
    19321 gcaaaaaacg ctaagcctag cttaaaaagc atttgacaca aggtatcgtc tatgttatta
    19381 tattagacgg tactttttac ttttggtctc tcaagagtgt acagagacgt gctgacaatt
    19441 gttgcaaaaa gtgcaccaga tataggctgt caccaagtgc tatatcaacc aaaattaaaa
    19501 aaacaggaga atgtagatgc ctacaattaa ccagttggta cgtaaaccac gtaaatctaa
    19561 aattgagaaa tcagattcgc cagctttgaa cattggctac aacagtcata aaaaagttca
    19621 tacgaagctt gctgctccac aaaagcgtgg tgttgcgact cgtgttggaa caatgacacc
    19681 taaaaaacct aactcagccc ttcgtaaatt tgcgcgtgta cgcttaagca accttatcga
    19741 agtaacagct tatatcccag gtattggcca caacctacaa gagcacagtg ttgtgcttat
    19801 ccgcggtgga cgtgtaaagg accttccagg ggtacgctat catatcgttc gtggagcact
    19861 tgatactgca ggtgttgcag accgtaagca aggccgttct aagtacggtg ctaaacgtcc
    19921 aaaaggataa tagaggaggg ataagaaaca atgagtcgta aaaatagagc gccaaaacgc
    19981 gaagtattac cagatccatt atataactca aagcttgtga cgcgtcttat caatcgtatt
    20041 atgcttgatg gaaaacgcgg aactgcatca tcaatcgttt atgatgcttt tagcgaaatc
    20101 aaagaagcaa caggcaacga tgctcttgaa gtatttgaaa cagctatgga caacatcatg
    20161 cctgtgcttg aagtgcgtgc acgtcgtgtc ggtggttcaa actatcaggt tccagttgag
    20221 gttcgtccag agcgtcgtac aacacttggt cttcgttggt tggtaactgc atcacgtgct
    20281 cgtggtgaac acactatgaa agatcgtctt gctaaagaga ttatggatgc tgcaaacaac
    20341 accggtgcgt cagtcaagaa acgtgaggat actcataaga tggctgaggc taaccgcgcc
    20401 tttgcacact tccgttggta agaataagat acgaaggtgt acagaacgca tagtgaagat
    20461 aggaagcttg acgaagagat ttttatctct aggaaagctt atctttttca cacagcgttt
    20521 agcctgagtt cagttttagg ctgttttagt gtgagacaaa tgctagccca aatcgggaaa
    20581 ttgacgcaga agcgatcatt tccagaagat tttatctttt tggcagacat ttgtcgctaa
    20641 aattcaacta atctaagatg tgagagtgtt aagcaagttc tagacaaact gatctattat
    20701 cttttttgtc agtgacttgc agctcaaact cagttacaat caagatgtat agacaaagag
    20761 agcaagattt taatagaaaa ttctcacctt caagatgagt tattgttttg atcggattgc
    20821 tcttaagtcg ggttttggtt tgcaaacata ctaaatgcta tctatcaaac atatcttagg
    20881 aaacgggtag gcctctgcct atccgttttt aatgaatagt gttataataa gatgtaaata
    20941 aaaaatatag gagaaaaaac ctaatggctc gcgaattttc actagcaaaa actcgtaata
    21001 tcggtatcat ggctcacgtt gatgctggta agacaactac aacagagcgt atcctttact
    21061 acaccggtaa aatccataaa atcggtgaaa cacacgaggg tgcatcacaa atggactgga
    21121 tggagcaaga gcaagagcgt gggatcacaa tcacatctgc tgctacaaca gcgcaatggg
    21181 atggacatcg tgttaatatc attgacacac cagggcacgt ggacttcacc attgaagtac
    21241 aacgttcgct ccgcgttctt gacggtgcag taaccgttct tgactcacaa tcaggtgttg
    21301 agcctcaaac agaaactgtt tggcgtcaag caactgaata cggtgttcca cgtattgttt
    21361 ttgccaacaa gatggataag atcggtgctg acttccttta ctcagtacaa acccttcacg
    21421 atcgtcttca agcaaatgct cacccaattc aattaccaat cggttcagaa gatgattttc
    21481 gtggtatcat tgacttgatc aaaatgaagg ctgaaatcta caccaatgac cttggtacag
    21541 atattcttga agaagatatt cctgaggaat acctagagca agctcaagaa tatcgtgaaa
    21601 agcttatcga agcagttgct gaaactgacg aagatttgat gatgaaatac cttgaaggtg
    21661 aagaaatcac taacgaagaa cttgttgctg gtatccgtaa agcaacgatc aacgttgagt
    21721 tcttcccagt gctttgtggc tctgccttca aaaacaaagg agttcaattg atgcttgatg
    21781 cggttattgc ataccttcca agcccacttg acattccagc aattaaaggg gttaatcctg
    21841 atactgacgc tgaagaagag cgtccagcat ctgatgaaga gccatttgca gcccttgcct
    21901 tcaagatcat gactgatcca tttgtaggtc gtttgacctt cttccgcgtt tactctggtg
    21961 ttcttaacag tggttcatac gtgatgaata cctcaaaagg taagcgtgag cgtatcggac
    22021 gtatccttca aatgcacgct aacagccgtc aagaaattga aacagtttac gctggtgaca
    22081 ttgctgctgc tgttggtttg aaagacacta caactggtga ctcattgact gatgaaaaag
    22141 caaaaatcat tcttgagtct attgaggttc cagagccagt tatccaattg atggtagagc
    22201 ctaagtctaa ggctgaccaa gataagatgg gtattgctct tcaaaagctt gctgaagaag
    22261 atccaacctt ccgcgttgag acaaacgttg agactggtga aacagttatc gctggtatgg
    22321 gtgagcttca ccttgatgtc cttgtagacc gtatgcgtcg tgaattcaag gttgaagcta
    22381 atgtaggtgc tcctcaggta tcttatcgtg aaaccttccg cgcttctaca caggctcgtg
    22441 gcttcttcaa gcgtcagtct ggtggtaagg gtcaattcgg tgacgtttgg attgaattta
    22501 cgccaaatga agaaggtaaa ggatttgagt ttgaaaatgc cattgtcggt ggtgtggttc
    22561 ctcgtgaatt tatcccagcc gttgaaaaag gcttgattga gtctatggct aatggtgtcc
    22621 ttgcaggata cccaatggtt gacgttaaag ctaagcttta cgatggttca taccatgatg
    22681 tcgactcatc tgagactgcc ttcaagattg cggcttcact tgcccttaaa gaagcagcta
    22741 aaacagcaca gccagctatc cttgagccaa tgatgcttgt tacaatcaca gctccagagg
    22801 ataatcttgg agatgttatg ggacatgtga cagctcgtcg tggacgtgtt gatggtatgg
    22861 aagcacatgg tactagccaa attgttcgtg cttatgtgcc acttgcagaa atgtttggtt
    22921 atgcgactgt tcttcgttct gcaacgcaag gacgtggtac attcatgatg gtatttgacc
    22981 actatgagga tgttcctaag tcggttcaag aagaaattat caagaaaaat aaaggtgaat
    23041 aatcacccct aagaggctgt ggatagtatc ccagcctttt tgatgtgtta caacagatgg
    23101 gcggtgcagc aattgatcaa agcaatgaca gaaaaatcaa gccctatcag gcataaacgt
    23161 ttaggaaaag gccttaagaa agcgctttta acaacattaa gcgacacttt tggctgccct
    23221 aaaaagctct ttgctgtctc aatattgatg gagaagcagt cttttgaaaa tgggtaatat
    23281 gtttgcattt tttctgaaat agttatataa tagttacgtt gaagggttgt tgcaggaatc
    23341 tgcaagttaa tcttttcaca ataggtaggg attagtccct ttaataataa ttcttttgat
    23401 tttcataagg aggaaatcac taatggtagt taaagttggt attaacggtt tcggtcgtat
    23461 cggtcgtctt gcgttccgtc ttatccaaaa tgtagaaggt gttgaagtaa ctcgcatcaa
    23521 cgacttgaca gatccagcca tgttagcata tcttttaaaa tatgattcaa ctcaaggacg
    23581 ctttgatggc gacgttgaag tagtagaagg tggatttaac gttaacggta aatttgttaa
    23641 ggtttctgct gaagctaacc ctgaaaacat tgactgggct tcacaagaag tagatatcgt
    23701 tttggaagca actggtttct tcgcttcaaa agctggtgct gaaaagcact tacacgctaa
    23761 tggtgctaag aaggttgtta tcactgctcc tggtggaaac gatgttaaaa ctgttgtttt
    23821 caacactaac cacgaaattc ttgatggtac tgaaacagtt atctcaggtg cttcatgtac
    23881 aactaactgt cttgccccaa tggctaaagt tcttcaagac aaatttggtg ttgttgaagg
    23941 cttgatgaca actatccatg gttacactgg tgaccaaatg actcttgatg caccacaccg
    24001 taagggtgat ttccgtcgtg cacgtgctgc agctgtgaac attgttccta actcaactgg
    24061 tgctgcaaaa gctatcggtc ttgttattcc agagcttaac ggtaagcttg acggtgctgc
    24121 acaacgtgtt ccagttccaa caggatctgt tactgagtta gtatctgtac ttgaaaaaga
    24181 cgttacagct gacgaagtga atgctgcaat gaaggctgct gcaaacgaca gttttggtta
    24241 cactgaagat caaatcgtat caagcgacgt tgtaggtatc cactatggtt cattgtttga
    24301 tgcaactcaa actaaggtat tgacagttga tggtaaacaa ttggttaaaa ctgtttcatg
    24361 gtatgacaac gaaatgtcat acactgctca gcttgttcgt acacttgagt actttgcaaa
    24421 aattgctaaa taatgactag agggcctagt ttacctaggc tcttttttgt gtcatgataa
    24481 aggttgctta tccctcattg gctagcttat tgctgaactt gcacttaggc ttaagctgca
    24541 cataggataa gtttttttgc taacgcttta gtgattagct gttctcagag agggtcattt
    24601 tagaaacctt cttaaggtga tatggctatc aagctgcctt ctttgaactg ctatgcttag
    24661 gctttgagtt taggtcttaa aagctttagg tgagtttttc gttataatta actgcataaa
    24721 gcatggcttt aagctcattt ccagcgcaaa tacctttttt ctttgcaaga tgtcaaagag
    24781 aagtactgta atggctcggg cttatctaca ttttttgctc agctattttt agctgttttt
    24841 tagctatggc tccatgaaat tgtgaagcgt tttcattttt attggttata gtcttgacaa
    24901 tctgaaatga tggtaataaa atgagaggtg gataaataac cgtacttaat aatgtatgga
    24961 atattaggag gattttatga catctaaaaa aattcttaac cttgtgtctt tagggttatc
    25021 gttggtttta atctctggct gtacgacaaa tggagagaaa aaagcagctc ctagtcaaga
    25081 caaggataag caagaaaagg ttgtccgtct aaccaatgat cagctaaggg ctagggaaaa
    25141 taccatggcc acactctggt atcagcagtc tgaagaggct aaggctctct acttacaggg
    25201 gtaccaagtg gctaagcagc gcttagatac attattgagt caagcaactg ataaaccata
    25261 ctctattgtt ttggacattg atgagacagt gctcgataat agtccttacc aggctaaaaa
    25321 tattaaagag ggcacaggct ttacgccgga ttcttgggat aaatgggtcc aaaagaaatc
    25381 agccaaggca gtagcaggtg ctaaggactt cttgcagtat gcaaatgaca agggcgttca
    25441 gatttactat gtttctgaca gaacgactaa gcaagtagag ccgactatgg aaaatcttga
    25501 aaaagaaggt attccagtgc aaggcaagga tcatttcttg ttcttagagg agggtgtaaa
    25561 atcaaaagag ggccgtcgtc aaaaggtgca agaaacaaca aatctagtgt tgttatttgg
    25621 tgacaatttg cttgattttg cagagttttc taagacctct catgaagata gaagaaagct
    25681 tttggatcag ctgcatgcag agtttggcag caagtttatc atcttcccta atccaatgta
    25741 tggatcatgg gaaagcagtg tctataatgg tcaaaaatta gacagtgaag gccaaatcaa
    25801 agcacgtgac aaggctttag aggcttatta aaagccctga tttgcgtgat tgctatgact
    25861 atgttgtggc ttcctgcctg cttaggtgat tgtgatctgc taaaaagagg tttacccaag
    25921 ggatttttca agcgctttga aaaattgtga aatagttaat ttattgtttt cagattttat
    25981 ccttatcaaa agaattgtgt tataatagag tgtactaaaa aatattaagg agtctatgaa
    26041 atggctaaat tgactgttaa agaccttgac ctaaagggta aaaaagtgct cgttcgcgtt
    26101 gactttaatg tccctttgaa aaatggtgtt attacaaacg ataaccgtat ttctgcagca
    26161 cttccaacaa tcaaatacat tattgagcat ggtggtcgcg ctatcctttt ctcacaccta
    26221 ggacgtgtga aggaagaggc agacaaggaa ggcaaatcat tggcgccagt agcgaaaaac
    26281 ttggctgaaa agcttggtca agaggttatt ttccctggta gcactcgtgg ggcagagctt
    26341 gaagctgcta ttgatgctct tgaggatgga caggttcttt tggttgaaaa cactcgcttt
    26401 gaggatattg acggtaaaaa ggaatctaaa aacgatccag agcttggtaa atactgggca
    26461 tcactaggag aaggaatctt tgttaatgat gcctttggta cagctcaccg cgctcatgcg
    26521 tcaaacgttg gtatctctgc aaatgttgaa aaagcagtgg ctggtttcct tcttgaaaat
    26581 gaaattgcct atatcaagga agctgttgag actccagagc gtccatttgt cgctattctt
    26641 ggtggttcaa aggtttctga taagatcggt gtgattgaaa accttcttga aaaagctgat
    26701 aaggtgctta tcggtggtgg tatgacctat accttctacg aagctcaagg tattgaaatt
    26761 ggaaactcac tttgtgaaga ggacaagctt gatgtggcaa aatcacttct tgaaaaatca
    26821 aatggcaagc ttgttttacc agttgattcc aaagaagcaa acgcttttgc agattacact
    26881 gaagtgaagg taactgaggg tgaagcagtt gatacaggct tccttggtct tgacatcggt
    26941 ccaaaatcta tcgctaaatt tgatgaagcc ctgacaggtg ctaaaacagt tgtttggaat
    27001 ggtcctatgg gtgtctttga aaaccctgat ttccaagaag gtacaattgg tgtgatggac
    27061 gctattgtga agcagccagg tgttaagtca atcatcggtg gaggtgattc agcagcggca
    27121 gccatcaacc ttggacgtgc agataaattc tcatggatta gtacaggtgg aggtgcttca
    27181 atggagcttc ttgaaggtaa ggagcttcca ggcttagcag ctcttacaga aaaataagct
    27241 gataccattt cggtgctgtc agtcgcaggc tgctatatgg tctgttaagg gctaagacag
    27301 ctgaaggctc acaaaggtgg cttatgttgc tggcggtgct tatgctaatt gttatgatta
    27361 acaagctgtc aaaggatagg ctagagcctg ctgtaccagt ctatcaggcc ttgctgtcag
    27421 ctactaaatg aatgagtcag aaaaaggtgc tatgtaggtg cctttttctg cgttttgctt
    27481 taggctgata gtgagtttgc ttgaagtcaa gactggcttc atgcaggctt cagagtcttt
    27541 gctaggaatg ctataaggtg ggttctgagc ttatctattt aggatatgtg acaaatgctg
    27601 ttaaaatatg ttacactagc attagcttta atttcaatag aaagtatctg atataggtta
    27661 tgaattatca ttttgatgcc tctaagttaa agttgggcat gcgtacgttt aaaactggct
    27721 tagctgtgtt ttttgttttg cttttgtttc atttttttga ttttcagggc ctgcagatag
    27781 gggccttgac agctgttttt agcttgagag agagctttga taagacgatc tcctttggca
    27841 cctctcgtat tttaggaaat tcgattggtg gtttttttgc gattatattt tacctgcttg
    27901 atactctttt tcagggcgca ttttgggtta ccttggtttt tgttccgata ttgacgatgc
    27961 taaccattat gtttaatgtg gcttttaata atcaatctgg catcatcggt gcagttgctg
    28021 ctcttttaat tatcaccttg tctattccta ctggcgaagc ttttatgtat gttattgctc
    28081 gggtttttga aaccttttgt ggggttttta ttgccattct tgtcaataca gacgtggagc
    28141 tgattagaaa taagtggttg agcaggaagc tcaaaaaatg atgtcagaaa acataacatg
    28201 tgaccttgac agtttattaa aatcaaccta taataggggt gtgaaaggaa gttttcatga
    28261 aagaaaaaga actcagacgc tcaatggcag tctttccgat cggtgcagtt atgaccttga
    28321 cagatctatc tgctcggcaa attcgctatt atgaggacca ggagctgata aagcctgaga
    28381 gaacagaggg caaccgtcgc ttgttttcct taaacgatat ggatagactt cttgaaatca
    28441 aggacttttt ggacgaagga ttaaatattg cggcaattaa gcgagaatat gctgaacgcc
    28501 aggataaatt aatgcaaaag caaaaggtat tgactgatgc agatgtgaga cggatcttac
    28561 atgatgagct tcttaatcaa ggtggctttt ccaccccttc acagcatatt gggaattttc
    28621 gtatctagca tacgactggc atgaaagaaa aaggagattg attaatggca atcacagcag
    28681 ctgatgttcg tcgcgaggtc aaagaaaagc atgtgacctt tcttcggttg atgtttacgg
    28741 acattatggg tgttatgaaa aacgttgaga tacctgcaac tgaggagcaa ttagataaag
    28801 tcctatctaa taaggtcatg tttgatggct cctcgattga aggctttgtg cgtatcaatg
    28861 aatcagatat gtatctctat cctgatttag acacttggat cgtctttcct tggggagatg
    28921 aaaatggaac tgttggtggc ttgatttgtg atatttacac tgctgaaggc aagccctttg
    28981 ctggtgaccc acgtggcaac ctaaaaagag ccttgaagca tatggatgag gttggctatc
    29041 agtcctttaa ccttggtcca gagccagaat ttttcttgtt taagatagat gaagctggag
    29101 aaccaacgct tgaggtcaat gacaagggag gctattttga cctcgctccg attgatctgg
    29161 cagacaatac ccgtcgtgaa attgttaatg tcttgaccaa aatgggcttt gaggtcgaag
    29221 ccagccacca tgaggtagct gtcggtcagc atgaaattga ctttaaatat gcagatgcct
    29281 tgaaggcctg tgataatatt cagatcttta agcttgtggt caaaaccatt gcgcgtgagc
    29341 acgggctcta cgctaccttt atggcaaagc cgaaatttgg tattgccggc tcaggtatgc
    29401 attgtaacat gtccttattt gataaagggg gcaacaatgc cttttatgat gaaaatgata
    29461 agcgtggcat gaagctatca gatgatgcct attatttctt aggtgggttg atgaagcatg
    29521 cttacaatta caccgctatc acaaatccaa cggttaattc ctacaagcgc ttggttcctg
    29581 gttatgaggc tcctgtttat gttgcttggg caggaagcaa tcgttcacct cttattcgtg
    29641 ttcctgcttc tcgtggtatg gggactcgtt tagaattgcg ttcggttgat ccaacagcca
    29701 atccttattt agcacttgcc gttttactag aggcaggctt agatggtatc attaataaaa
    29761 ttgaagcgcc ggcaccgatt gaggctaata tttacatgat gacagcagag gagcgcaatg
    29821 ctgctggcat tgttgattta ccgtcaacac tccataatgc tctaaaggcg cttcaaaagg
    29881 atgaggtcat tcaaaaggct ttaggtgatc atatttacac caacttttta gaggcaaaac
    29941 ggattgaatg gtcttcctat gcgacctttg tttcgcaatg ggagattgat aattacttac
    30001 acaactatta gaaaatcaaa actcactcag ctttttgagt gagtttttta tgcttttatt
    30061 cagcagatat ggttatttat acttatcgtt ccttttatac gctatgagga cagaagtgtc
    30121 tggtttatct atttataaaa ataaaatcaa aaattttcag ataaatctat ttcctttttt
    30181 cagaattatg gtataatcta atttaattat tttaaataac tattttgtta ggaggaaggt
    30241 tatatgacag tactaggaac aaaagcatgt aagcgtctgg gcttagcggc agttacgcta
    30301 gcctctgttg ctgccttgat ggcttgtgga aataagcaat cagcgtcaac agacaaaaag
    30361 agtgagatta attggtatac gccaactgag atcatcacac ttgatatctc aaaaaataca
    30421 gatacctatt ctgctttggc tattggtaat tctggcagta accttttgcg tgctgatgct
    30481 aaggggaaat tacagcctga tttggctgaa aaggttgatg tgtcagagga cggcttgacc
    30541 tatacagcaa ccctgcgaga tggcttgaaa tggtctgatg gtagtgatct aacagcagag
    30601 gactttgtgt acagctggca gcgaatggtc gatcctaaga cagcctcaga gtacgcttac
    30661 ttggcaactg agtcacatct gaaaaacgca gaggacatta atagcgggaa aaatcctgat
    30721 ctagactctc taggggtaaa ggctgatggg aataaggtta tttttacctt aacggagcca
    30781 gcaccacaat ttaagagctt gctgtccttc tctaactttg ttcctcaaaa agaatccttt
    30841 gtcaaggacg ctggcaagga ctatgggaca acatcagaaa aacaaattta ttctggtcct
    30901 tatattgtca aggactggaa tggcactagc ggaaccttta agctagtaaa gaataaaaac
    30961 tattgggacg ccaaaaacgt caaaactgag acagttaatg ttcaaacggt taaaaagcca
    31021 gatacagctg ttcaaatgta caagcaaggt aagctagact ttgcaaatat ttctggtacc
    31081 tcagctattt acaatgctaa taaaaagcat aaggacgttg ttccggttct tgaggcaaca
    31141 acagcctata tcgtatataa ccagacagga gctattgaag gcttgaacag tcttaaaatt
    31201 cgtcaagcct tgaatttggc aacagaccgt aagggaattg tatctgcggc tgttgataca
    31261 ggctcaaagc cggctacagc gctggttcct acaggtcttg ctaaattatc tgacggaaca
    31321 gatctaacag agcatgtggc acctggctat aaatacgatg acaaggaagc tgcaaagctc
    31381 ttcaaggaag gcttggcaga gctgggcaag gatgccttga caatcaccat cacagctgat
    31441 gctgatgcgc cggctgccaa gtctgcagtg gattacatca aggaaacctg ggaaacagct
    31501 cttcctggct tgaccgttga agagaaattt gttcctttca agcaacgtct tgaggatact
    31561 aaaaaccaaa actttgaggt tgcagttgtt ctttggggtg gtgattatcc aaaagggtct
    31621 accttctatg gcttgtttaa atcagggtct gcttataact atggtaaatt tacgaatgca
    31681 gactatgatg cggcctacaa caaggctcta acaacagatg ccttgaatac agatgcggct
    31741 gctgatgatt ataaggcggc agaaaaagcc ctttatgaca atgcccttta caatcccctt
    31801 tacttccgta gcggtgaagg cctgcaaaat ccaagcatca aaggtcttat ccgtaattca
    31861 actggtctaa atgttgactt tacttacgct tataaggact agcaataata ttattgtaag
    31921 cctatactga cctagcaagg ccacagctcc ttgatgggaa gtgtttaaga gaagcttagg
    31981 gctagctagg agtgtctatc ctgtaggcct tggcaagcat attgcaagaa ttggtcttaa
    32041 ccagttcttg cttttggtta gaggaaaaat atgattaaat atcttttgaa gcgagtggct
    32101 attttagtag tgacactctg ggtggtgatt accctgtcct tctttttgat gcaggtgatg
    32161 cctggaacac cctataacag tcctaaatta actgatgaca tgattgctat gctgaatcag
    32221 cagtacggct tagataagcc tctttggcag caatatttga agtatttgtt tgatattctt
    32281 catggtgact ttggcaccag ctatcagtcg attaatcaat cagtgacaac cctgatctcg
    32341 cagcgtctgg gggtatctgt gcacttagga gtacaggcgc ttattgttgg tattagctct
    32401 ggcttagctg ttggtgctgt ctcagcgcgg aataaaaata atagcattga tgccatttta
    32461 agtgttatct caacgcttgg tatttccatg ccgtccttta tcattggctt gctgctgctg
    32521 gattatttgg gctttaaatg gaatttactt cccttgtctg gctggggaag ctttgggcaa
    32581 acgattttgc cgacgcttgc tttagctatt ccggtctttg ctcaggtgac ccgttttttc
    32641 cgcagcgaga tgatcgagac cttatcgaca gattatattc agctagctag ggcgaagggc
    32701 ttgactaagc gtcaggtgac tcgtcggcat gcttaccgca attcgatgat tcctgtgtta
    32761 accttggttg gtccgatggc tgctggtatt ttgacgggat cagccctgat tgagcagatt
    32821 ttttccattc cggggattgg gcagcagttt gtgacctcta ttcccaccaa ggattaccca
    32881 gtgattatgg gaacaacgat tgtctatgcg ctaatgctga tggttgctat tttggcaact
    32941 gatatgatca ttagtatcgc agatccacgt gttcgtttgg gataggagag tgctatgcta
    33001 gaagaaacaa aatcatttaa gcttgttgga gcaggtagct tagcgacaca agaaaaaatt
    33061 gaaaagccgg cgctttcctt tcttcaggac gcttggcgta ggctaaagca caataaacta
    33121 gctgttattg cgatggggtt tttagctgtg ctgcttttgt tttctattgg ttctttattt
    33181 gttgtatcta cagatgatgc caatagcttt aacagtaagg aggtaagcat ataccgtaac
    33241 ctgccgccaa agctaagcag cagcttgcca ttttggaatg ggaccattac ctacgctggt
    33301 aatacagagc ccaatgacgc ttatgcggat caaggggtcc cagaggacaa ggccttctta
    33361 ctcgggacgg ataatctggg gcgcagtatt ggaaaacgta ttacggtagg gattcgtatt
    33421 tctcttttga ttgctattgt cgcaaccctg atcgatctag tgattggggt aacctatggc
    33481 ttggtctcag gctttgttgg tggcaagact gacatggtga tgcagcggat cattgagatt
    33541 atctcctcta ttccaaacct tgttattgtg accatgcttg gtcttttgct tggcaatggt
    33601 gtgacttcaa ttattatttc aattgcgatt gtaggctgga cctcaatggc taggcaggtc
    33661 cgcaacctaa ccctgtctta tcgagagcgt gatttcgtcc ttgcttctcg tgccttggga
    33721 gaaagtaata tcaggattgc ctttaagcat gtattgccaa atatttcagg gattattatt
    33781 gttcaaatca tgatgactgt tccgagtgct atcatgtatg agtcagtttt atctgcgatt
    33841 aatttaggcg ttaagccacc gacagcttcg attggttcat tgattactga tgcacaagaa
    33901 agcctgcaat attatcctta tcaggtgctg ctgccggctt ttgccttggt gttaatttcg
    33961 ctagccttta ttttgttggg tgatggcttg cgtgacgctt ttgatccaaa atcaagtgat
    34021 gaataggggg aaataaaatg acgaatgaaa ccattttaag tgtcaaaaac ctccatgttg
    34081 attttaaaac ctacgctgga gatgttaagg cgattcgtga tatcagcttt gagctaaaaa
    34141 agggagagac tcttgcgatt gtgggagaat caggctcagg gaaatctgta accactcgca
    34201 cgctgatggg gttaaatgct aagaatgcaa gtatttcagg gaatatttgc tttaagggca
    34261 agcagctcaa tgagctgaag gaggaggaat gggtcaaggt gcgtggcaat gaaattgcaa
    34321 tgatcttcca ggatccgatg accagccttg atcctaccat gacaattggc atgcagattg
    34381 cagaggcaat aatgattcat caaagcattc ataagacaga agccttgaag cgtgctttag
    34441 acctgatgcg tcaggttggt atcccaaatg ctgaggagca ccttaaggat tacccacatc
    34501 agtggtctgg gggcatgcgg caacgggctg ttattgccat tgctctagct gccaatcctg
    34561 atattttgat tgcagatgag ccgacaacag ctcttgatgt taccattcag gcccagattt
    34621 tgaagctgat gaaggatatt cagtctcaga ccgcatcatc gattatcttt attacgcatg
    34681 accttggtgt tgttgctgga atggtagatc gcgttgctgt catgtatgct ggaaagattg
    34741 tcgaatatgg aacggttgac gaggtatttt atcatccgca gcacccttat acctggggct
    34801 tgctcaattc gatgccaaca acagctactg cagcaggtag cttgaggtct attcccggaa
    34861 cgccgccaga tttattaaac cctccaaagg gagatgcttt tgctgcccgt aatgagtttg
    34921 ccctagacat tgaccatatc aaagagcctc caatgttcaa ggtaagtgac agccactacg
    34981 cagcaacctg gttgctagat gagcgtgctc ctaaaataac ccctccattc ccaatccgca
    35041 agcgttgggc aaaatggcag gaaatggaag agaggaaggc ttaatgacag aagctcgtaa
    35101 aaaattaatc gaagtaaaga atgtttcctt aacctttaac aaggggaaga aaaacgaggt
    35161 taaggctatt gatcgcctta gctttgacat ttatgagggg gaagtatttg gccttgttgg
    35221 ggaatcaggc tcaggcaaga cgacagttgg tcgagctatt ttgaaactgt atgacattag
    35281 tgatggtgag attatcttta acggagaaaa tgtctcccaa ttaaaaggga aaaagctgca
    35341 tagctttcgt aagcatgcac aaatgatctt ccaagatcct caggctagtt tgaacggccg
    35401 tatgaaaatt agagacattg ttgcagaggg cttagacatt catggcttga cagcctcaaa
    35461 ggcagagcgt gaagcaagag tccaggagct gttaaagctt gttgggctca atcagaacca
    35521 tttgacgcgc tacccacatg aattttccgg tggtcaacgc cagcgaattg gcattgcgcg
    35581 tgccttggct gtgaagccga cctttattat cgcagatgag ccgatttcag cgcttgatgt
    35641 gtcgattcaa gcacaggtag tgagtctcat gcagcaattg caaaaaaagc gtggcttgac
    35701 ctatctcttt atcgctcacg atttgtctat ggtcaaatac atttcagacc gtattggtgt
    35761 gatgcattgg ggcaaaatgc ttgagattgg gacatctgat gaggtttaca atcacccgat
    35821 tcacccttat acgaaaagct tgatctcggc cattcctgag ccggatcctg aaaaggagcg
    35881 taagcgtatt gcagaggttt atgatcctag ccaggagcta gatggccaag agcgacaaat
    35941 gcatgaaatc actcctgggc attttgtctt agcgactcag gccgaagccg agcagtaccg
    36001 agcagagtgt ggcctttaag agactagcat aacagcaatt tcctaaaaag gctgatgtga
    36061 tagtttttta ggtatgacag accaaaagtc gtatgacctt tgccgatcaa aagcaggtgc
    36121 catgcgattt tggtggtatg gtggagcttt gtcagccaac ctagactgca caaaaagctc
    36181 cttatgatag aatttgtagc atgaggttgc gacacaagtc taccctaaaa taaaacaaaa
    36241 taaaacaacc gaacaggtct agctttctga gatttcaaaa gccagacctg ttcggttttt
    36301 aatgaatgag actaggtcat aaagtatctt agttaagatt gtctaaagtg cagctctttt
    36361 tgctgtgctt gctgctgttt ttataaaatg actcgtggga atcaatcagc ctgtagtcaa
    36421 atgttatcgc tctctttttg agatgtggct tgacaggttt gctaagctca gcaggctatt
    36481 tttagtagta tagctagaca aaggccctta agctagctca gcacgtcact ctgttaagct
    36541 tagctaacag cacgtgttgg gcaagtagta tgcctcatag ccttgtacgt cagtcattga
    36601 cgttgacgca acaaaaaaac acgagtctct aagctcgtgt caaagatcta ttggctatca
    36661 ggcgttagaa ccatcggaat gataataggc tcgcgctctg tcttttcgta aaggaaggga
    36721 cgaagcgcat taacgatagc accattgaca gactggatac tagcgtcctt atttttcaga
    36781 gcgatacgaa tcgcattgaa aagcacgcgc tgactctctc tgatgagctc gcctgactcg
    36841 cgcatgtaga taaagccgcg gctgagaata tctggtccgg ctaagatcat ctgtgtctca
    36901 aaatcaacag tcgccactgc aaggacaacc ccgtcctctg aaagatcacg acgatcgcga
    36961 aggactgctg tcccaatatc tccaatgcca ttgccatcta cataaatgtc ctgagcattg
    37021 aaatgaccgg ctatacgagc gctatcactg gtcaaggcca atacgtcacc attttccatg
    37081 ataaagatat tttcctctgg aatcccaata tcaacagcaa gcccagcatg aaccttctgc
    37141 atacggtatt caccatggac aggcataaag tattttggct taataaggct aagcattagc
    37201 ttttgctcct gctggccacc atgaccggag gtgtggatat tgttgacctt tccatgaata
    37261 acgtcaactc cagcctcctg aatcgtattg attagcttat tgacgctgac ggtattacca
    37321 ggaattggac ttgatgaaaa gatgacagtg tctccaggct gtaagctgac ctgtctgtgg
    37381 gtaccattgg caatcctagc aagggcggcc atagactccc cttgactgcc ggtacacatg
    37441 atcaaaatct cactagcgtg gtaatgttta atctcattag gctcaataaa ggttcccttt
    37501 gggaccttga tgtagccaag ctcaataccg ttaacaatag ccttttccat tgaacgacca
    37561 aatacagcaa tcttacgccc tgtcttaaca gcggcttctg cagcctgctg caagcggtag
    37621 atatttgaag caaaggaagc aaaaatgata cgtccatgaa tgccttcaat aatgttcatg
    37681 attgactggc caacgacctt ttcagaattc gtaaaggttg gtatctcggc atttgtcgaa
    37741 tcggacaata gacaaagaac cccgtcctta ccaagagcag ccatgcgatg tagatcagcc
    37801 ggatcaccaa caggtgtaaa gtcaaacttg aagtcgccag tacagatgac tttcccttgt
    37861 ggggtgtgga taacaatccc aagtggctct ggaatagagt gagttgtttt aaagaaggta
    37921 acgctcatat gcttaaaggt gagctcggta ttgtgattaa tctcatagag cacagcatcg
    37981 cgtaagagac cgtgctcctc cagctttcct cggataagag ctagagctaa ggggcctgca
    38041 tatataggca cattagcttg ctttagtaaa aaaggaatac cgccaatatg atcctcatga
    38101 ccatgagtaa tcacaagagc cttgacgcgc tccaaattgt caacaatata agagtaatcg
    38161 gggataacat agtcaatccc tagcagatcg tcctctggga atttgatacc ggcatcgaca
    38221 atgatgattt catcttgata ctcaataccg taggtgtttt tgccgatctc tcccagacca
    38281 ccaatcgcat aaaccccaac ctcattaggc cttaaactga tatttgtcat gttaaaactc
    38341 cgttaatgtg aaaacaccag tttctttttc gtagtctagg tgcttgtctg agagcagctc
    38401 gatgaattcg acattgtaat cggtgtgctc ttcaaccatc ttgcgggctt tgatacgccc
    38461 ctcaagctca cttgcagcgt ctatatctag gtatagggcc tgtgtgtttt cacgacgcgg
    38521 actgcgttcc tttgtttctt ggtagaaaac tttataaatc attgatgata tcttcctttc
    38581 atgatgaatc gattatccaa acaataacaa ataggtcaaa acgagaaggc ctctgttttg
    38641 acgattacct atcatgtgat tattgtgtaa tagatttaaa cctgattctg tgcaattact
    38701 aagattatac catactatcg gcttttagta aaaagtttcg ataaaattat tctcttgacc
    38761 ggtgatgagg ctgtggctgt ctccttttcc atgaccttta ttttatgtta taattgtgga
    38821 atagaaatga cttgagaagg gcttagtatg aagacacttg catttgacac atcaaataag
    38881 gcattatctg ttgctctatt agacgatggc acattattgg ctgatcttac gattaatgtt
    38941 aagaagaatc acagtattag tctgatgccg gctattgatt ttttaatgtc ctcagctgac
    39001 ctgaagccaa aggatcttga tcggatcgta gtagcagaag ggccgggctc ctatactggc
    39061 ttgcgtgttg ctactgctac agcaaaaatg cttgcttata gcctaagtat tgacctcgtt
    39121 ggcgtatcaa gcctatatgc cctagcggct tctacttgcc gagaaaaccc tgatagcttg
    39181 gttgtccctt tgattgatgc tagacgacgc catgtttatg tgggctatta tcaccatcaa
    39241 aaagctgtga aacaggataa gtacgcgtcc tttgatgctg ttttagcaga actggtctct
    39301 tgtgaccatg tgatttttgt tggagaagtg gagggctttg cagaggacat tcgatcagcc
    39361 ttgccagagg ccaagataaa gccaagtctg ccatcggctt ttgaggttgg tttgctaggc
    39421 agcagccttt cagctgacaa tgtagcagcc tttgtcccac aatatttgaa gcgggtcgag
    39481 gcagaggaaa actggctcaa aactcatgct gccggtgatg acagccagta tgtcaagcga
    39541 gtttagcgat gatgtctatc caagaaaaag cagcagctgt ctatcaggtg ctaaaagagg
    39601 tctatggtca atccccttgg accttaaagc agatagtgtc tgatatgcag caggagcatg
    39661 ttgattattt taccttttat catcaggaga ccctgctagg ttttttagcg attcaacagc
    39721 tgccaggaga aatggaaatc actaatctag ctgttttgcc aagctatcag gggcaaggga
    39781 ttgcctcttg gctcatggga cagctagatg gctttgaggg agtgatattt cttgaggtta
    39841 gagcgtcaaa ccatagggcg cagcagcttt accttaagca tggctttgag gtggtaggcc
    39901 agcgtagcaa ttattatcat gatccaatag aagcagcctt gatcatgagg cgggaaggaa
    39961 agaatgacag atagatatat tttagcagtg gagagctctt gtgatgagac aagtgttgct
    40021 atcttaaaaa acgacaacgt cttattgacc aatattattg ctagtcaggt tgaaagtcac
    40081 aagcgttttg gtggagtggt tcctgaagtg gctagtcgtc atcatgtgga ggtgattacg
    40141 acttgctttg atgacgcact caaggaggcc cagcttgagg cttctgactt gactgcggtt
    40201 gcggttacct atggaccagg tctggtgggg gccttgctag ttggcctagc agcagccaag
    40261 gcctttgctt gggctaatga tttgcccttg attccagtca atcatatggc agggcacctg
    40321 atggcggcac gcgagcaagg agagctggaa taccctctta tggctctctt ggtttctggt
    40381 gggcatacag agcttgtcta tgtgaccgag ccaggagaat atcatattgt tggagaaaca
    40441 cgtgatgacg cagttggtga ggcctatgat aaggtaggac gtgtgatggg cttgccctat
    40501 cctgctggtc gtgagattga tcagctagct caccaaggga cagataccta tcattttcct
    40561 cgtgccatga tgaaagagga tcatttagaa ttttcttttt caggcctaaa atcagccttt
    40621 atcaacctgc accataatgc gcagcaaaag ggtgaggagc ttgtgcttga ggatctctgt
    40681 gcttcctttc aggctgcggt gttagatata ttgttagcaa aaacgaagaa ggcactcaag
    40741 cagtatccat caaaaatgct agtcgttgca ggtggagtgg cagctaatca gggacttcgt
    40801 gagcgtttag ctgaggaaat aactgatata gctgttgtga taccacctct aagattgtgt
    40861 ggagataatg ctggtatgat tgcgttggcg gcggtggttg agtacgagaa agggcatgtg
    40921 gcaggcttgg atctaaatgc taagccgagt ctagcctttg atagctttca tcagcagtag
    40981 tattagtatg aggagattgt catgttttat ttattgcttc ccccattgat ttgcagtgtg
    41041 gtatttttgg ctgtctatat taaggagcca agaacgctgt ggctaggagc tagctttgtg
    41101 acgaccctag gtgttagtct cttgtgtgct atgatttaca ttttttcaat cgaagaaaag
    41161 cttcagggag ttggtatcct agtgctaggt gttattgggt ttcttgcgat tgtatggttg
    41221 atgtctagtc cctttatcct cttgctcttt ctaagcttta atggcattag gctcatcaaa
    41281 agagaggggc tttcctttcg gaatttattg ctgattggct cagcggtgct attgtttgta
    41341 catcctttta tcagcagact attgttagag agtatcggtg attcaaagct tttaaggatc
    41401 atgtatgaaa cgagtgacct cttaatcctt tacctcttgt taatcgtatc agtctacacc
    41461 atctcaagca tgctgaatac cttttacttc agaaaaacca aggaggatta tattattgtg
    41521 ctgggcagcg gcttaaatgg agaccaggtc acccccttgc tagctagccg cattaataag
    41581 ggcattcaga tttaccagaa aaatcctggc agcaagctga tcatgtctgg tggcaaaggg
    41641 gctgatgagc taatagctga gggtgaggcg atgtgtcgct atgcaatcca gcaaggaatc
    41701 aaaagtgaag atatattagt tgaaaaccaa tccagaaaca ccagagaaaa tattctgttg
    41761 tctaagcaat taataccatc tggagcttcc ttttgcttgg tgaccaatcg ttaccacctg
    41821 tttagagcct tattactggc taaggagcta gccttgcctt gcaggtgcta tggggcaaaa
    41881 acaaagctct actttagtat gaatgccttt atcagagaga ttgttggcta tctccaatta
    41941 aagaaaaagc agcacctgct ggcaatgctc atcttaacag taggctatat agccataaga
    42001 gtggtgatga tctatatgct gcacatttga tgtcattggc aaaaaagcta aggctagtca
    42061 cctcgtcttg ggctgaaaaa gtctctctta ggtccttttc tcagatgata tgagcaagca
    42121 gcctttttaa aaaggctaca tctaggattt tatggagcct tagagcttgt tgtgtggtga
    42181 tgttcaatgg aaccaatcac aattgttaca gcaaaaagca ggcctttagg aacgtttgct
    42241 ttgctggtaa gtccttttac ttgcagaggc tggctacacc agccaaaggc taaggcaagt
    42301 gatttagctt gtgatgatca aggagtttta agacgtaaaa aaatagctcg gtatcttggc
    42361 ataccgagct atcatgataa attggcttct atgattacta aatcttaaac aaggtgagtc
    42421 aagcttacca gctagcctta gtgattcctg gtagttggcc tttgtgagct agctcacgaa
    42481 aattgatacg gctgacacca aacttacgca tgtaagcatg gggacggcca tcaattctat
    42541 cacgattttt caagcgattt ggatttgaat cacgtggcaa tttgcgcagt gcttcataat
    42601 caccctttgc tttaagctcg cgacgaaggt cagcatactg ttcaatcagt tggagctgct
    42661 tatggtattt agcaattttt gacttctttg ccattgcttt ctccttctta atatttaata
    42721 atctcagagc gttatcagca ccctgaattt cctcaaccag tcattaatca gttaagaaaa
    42781 catagctcta ttatacacta atttcaatca aatgcaagaa aaatagataa ctgattaacc
    42841 agttgaggca aaaacagcct gccagtgagt ctactgacaa gcctagctta gctttgcgag
    42901 cttcctgcca cccagccaga gcagagggca gctgtaatgt taaagccacc tgtatgagca
    42961 ttaacatcta agacctcacc agcaaagtaa agtcccgcga cctttttgct ttctagggtc
    43021 ttagggttga tttcttttaa gtcaatgcca cccttggtta caaaggattt ggccagagat
    43081 atttttcctg tgattggaat cggtaattgc ttaatcctgt tgacgagctc ctgagtctgt
    43141 gtgggagtta actgctttcc tttttctgga tagccctttg ctaaaaaatc agcgactcgc
    43201 tcaggcatca aagtcttgag cgcattttta agggcctttt cccggtgctg cgctagatag
    43261 ctgagcagct cagctgcgga ggtttgtggc agcaggtcaa gctctgcgat gtcacctccc
    43321 ttaacaaagg aggaaagcct gagagcagcg gggcctgaca acccaaaatg ggtaaaaagc
    43381 aaatcgtgag tgatctgatg tttcccacag ctaagggtca catcagcaag tgaaatcccc
    43441 tgcagagcct tatgtggaaa gtctgttaat aaggggcttt ccgcagcctc tagctcggtg
    43501 acagctatgt taaagtggcg agcaatatca tagccaaagc ctgtcgatcc agtagatggg
    43561 taggacttgc ctcctgttgc cacgataagc ctctcgcagc tgaaggtttg atcaactgat
    43621 ttgaggtaaa aaaggttatt ccgctttttg accgagacaa tctcggtact gatcagcacc
    43681 tgagctccta gtgacttgat tttttgctcc agcgcattga taatcgtctt tgattgatcg
    43741 gtcgtaggaa acatgcgtcc atgatcctct tccttgaggg tcaccccatt ttccttgaaa
    43801 aaggcaatga tgtcatgatt atcaaattgg gaaaagacgc tatagagaaa gcgcccgtta
    43861 ccgggaatgc ccgcgattag ctcatcatgg cttccgctat tggtgacatt gcagcgtcct
    43921 cctccagtcc ctgctagctt tttgcctagg cgcttgtttt tgtcaagtag gagtgtcttg
    43981 tagccatagt agctactaga gatggctgcc atcataccag caggaccacc tccaataata
    44041 atcgtgtcgt atagtatcat gtgcttattt tagcataaca tcaagcgatt taacagtaat
    44101 gtaaactagg ctaaattgac agaattctgg tattgtgtta ctatttttaa taagaatatt
    44161 cagttacagt aataaagagg aaattatggc aatagaaaag acagttagtg aactagctga
    44221 cattttggga gtgagccgcc aggctgtcaa taatcgtgtc aagtccttac cagaggagga
    44281 ccttgataaa aatgataaag gggtcactgt cgttaagcgt agtggcttgg ttaagctgga
    44341 ggaaatctac aagaaaacca tttttgatga tgagccaatt agtgaagaga ccaagcagcg
    44401 tgagctctta gagattctgg ttgacgaaaa aaacactgaa atcactcgct tatatgagca
    44461 gctaaaggca aaggatagcc agctggctgc taaggacgag cagatgcgta ttaaggacgt
    44521 tcagattgcc gagaaggaca agcagctgga tcagcagcag cagctgacag ctaaggctat
    44581 ggcagacaaa gagaccttga agctggagct tgaggaagca aaggctgagg ctgatcaggt
    44641 acgactgcaa gcagaggaga tacagtctga aatgggacct aaaaaaggtt ttttaaatcg
    44701 tttatttggt aaataacagt ataccaagac cctctaaggg tcttttttga ggagagaaga
    44761 atgaaacaat tagaagcata tattgccttt gatatggaat ttaatactgt caatgaggtt
    44821 agtcatatca ttcagctttc agcggtcaaa tggcacaagc atcaggaggt tgacagcttt
    44881 gacagctatg tttacactgc tgttcccctg caaagcttta tcaatggcct gacaggcatt
    44941 acctcagata agatcgtatc agcacccaag gttgatgagg tgcttgatgc ctttaagcaa
    45001 tttgtcggtg acacgccttt gataggctat aatgcacaaa agtctgattt gcctatttta
    45061 gcagcaaatg gcttggatct gtcagcgcaa tatgcagtcg atgtctttga tgaagcctat
    45121 gagagacgaa gcagcgacct aaacgggatt gctaatcttc gcctgcaaac agttgctgat
    45181 tttttaggga taaaaggaag aggacataat agcttagagg acgctcgtat gacagcgcgt
    45241 gtctatgaag cgtttgtgga atttgacgac aataagtctt acctaaacaa acaaaaagaa
    45301 gcgattgcag ataacccctt tgcagctctg ggagggcttt ttgactagca gcgctagtca
    45361 tttctctgaa aaagaaaaat gacctaaggt cagggcttgc ttgtgacctt gggtcatatt
    45421 ctataatgag gacagaaagg aggtgaagga catgtctgat atttactcaa ctggtgagct
    45481 agcaaaagca gcaggtgtca ctgtcaggac agtgcaatat tacgataagc gtgggatttt
    45541 gttgccttcc cagcttactg aaggtggacg gcggatttac accgagtcag atttggagcg
    45601 attgaaaatc atttgcttct tacgggacct agatttttcc attgagcaga ttaagcgcgt
    45661 gctagcagaa gacaatgtta tggcggtgct tgacctcttg ctggtggatc atatccaaca
    45721 gctggaacaa gacttaagga caaaaaagca tcagcttgac acagctgtca agcttttgtc
    45781 aggtattcgc tgctcatcta gtcactctat caaaaaccta tcagacatgt cacttaccat
    45841 gaacaatcaa aaagcttggc gtcgtttgca gttgaaaatg tttagtaata ttgccctagc
    45901 aatattggtt catgtgatgt tagtgttact aactagctat tttcatctat cttggttggt
    45961 atggatagag gctccactat ggataatctt ttttacttta ttgatcgttt attttcgtaa
    46021 acaatttgag tacctatgtc caaattgtca tactattttt gaaccagact ttaaagagtt
    46081 tgccttggca ggtcacacac caaggacccg caggctgacc tgtcctcatt gccatcaaaa
    46141 atcttactgc cttgaattgg ccaaggaaaa ataatggaaa atctccgctg gatacccagt
    46201 ggagatttct tgctattaga atggtagctt gccagcaaag gctcctagag ttttcttagt
    46261 cgcctcatca atttgagcga gggctgcatt gatggcctga gcagtcatat cctgaagtgt
    46321 ctctatatcc tctgggtcaa cgactgcttc cttgaaatca atgctaacca attgcttatc
    46381 acctgtaaag gttgcagtga ccagctcctg agctgacttt cctgtaaatt gcatagctgc
    46441 taggtcagcc tgcttttgtt ccatttgctt ttgaagcttt tgcgcttgct tcatcatgtt
    46501 ttgcatgttc atcataagtt ccaattctcc taagttttga tacttaacta ttataacata
    46561 tcagacaaga cttcaaacat gtgatctttt aaagttaatg aaaaggccct gctagcctgc
    46621 aatgctttga tgtgctagcg actaacgaac aggtcgtttc ctttaaatag agttttcttg
    46681 ttgagcttta tagctggtgc ttgtttttgt gatgagcttg tgtgaggctg tcgttagtgt
    46741 tgttttaggt ggtttgacat caggagcgat taaaaaagtt atcagtttac atttttataa
    46801 taataactta agaattaatt taactttaga ttaatcttac tttatatttg attgctatac
    46861 ttagtccata acataaataa ccaaaaagaa agaggtaatc gttatgacaa caatgactac
    46921 aacaaaacaa tcaaagacaa ctctagcagc tcgttatttg aagcttggtc ttacttcagc
    46981 aatgtttgct ggaggagcct ttctagctct aggctcagca ccggctgtct ctgcttctac
    47041 ccatgctggt aatgatcagc cagcgactca acgcttaact gatcaggaga tctacgaacg
    47101 tgctcaaaag ctagacttgc cagactatgt gagaggctca atctacggta ttctcaacca
    47161 aaactcaagt gttacttatc caaaggatat agcaggtcta gagcagtcag aagctccaca
    47221 accccctgca gctccacagc tcactgacca agatgctcaa aagctggact tgccagacta
    47281 tgtgagaggc tcaatctacg gtattctcaa ccaaaattca agtgttactt atccaaagga
    47341 tatagccggt ttagagcagt cagaggctcc acaaccccct gcagctccac agctcactga
    47401 ccaagatgct caacagctag acttgccaga ctatgtgaga ggctcaatct acggtattct
    47461 caatcaaaac tcaagcatta cttatccgcg cgattattaa gcatctaaga tgattaaggt
    47521 gcacaatcga cgattaaaat gattgatgag ttaatgagat tagaattatt tggctaagtt
    47581 aagaattagt gttatacttg agagagtgta gcactaattt tttaatcaag gaggaagcat
    47641 gacctacaag atattattgg tggatgatga attggaaatt attgatatta acgaacgtta
    47701 tttgcaacag gcagggtatc gtgttaccac tgcaagcgat ggtagtcaag ccttggagct
    47761 ttttcataag gatcagtacg atttgattat cagtgatgtt atgatgccca atatggatgg
    47821 ctatgatttt attggggagg ttttactgga aaagccagat cagccctttc tctttatcac
    47881 tgcaaaaaca tctgagcctg acaagattta ttccttgagc ttgggagcag atgattttat
    47941 ttccaagccc tttagtccac gtgaattagt cttacgggtc aaaaatattt tgaatcggat
    48001 ttatggtaag gctaaccaag ctgactcctt agttattggg gatttggtca tggatcacag
    48061 cactcgaagg gttacagtgg caaatcaaga tctgaatctg accaacaagg cttttgattt
    48121 gttgtggatt ttggccaatc atttgaatca tgtcttttca aaaacagagc tttatgagcg
    48181 t
//
LOCUS       DARYNN010000012        44665 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.012, whole genome shotgun sequence.
ACCESSION   DARYNN010000012 DARYNN010000000
VERSION     DARYNN010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 44665)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44665)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44665
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.012"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            398..811
                     /locus_tag="TVB59_000615"
     CDS             398..811
                     /locus_tag="TVB59_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL1009547.1"
                     /translation="MLNKMKRLHYLMIFRLLTGQLPAISLMAVLLSKDIHRLSLGSLI
                     SFAIFAVSTAASNYYFSREIAIEQLKEQTRPNLLLTQILFIVVFMIIGIVSIYCGLSS
                     SEFYKQVIAVICSFISFVTMGLMIWGIRYAKAYRR"
     gene            1071..1652
                     /locus_tag="TVB59_000616"
     CDS             1071..1652
                     /locus_tag="TVB59_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HEL1009548.1"
                     /translation="MRRIRLATLADAKALLDIYRPYVEETAVTFEYTVPSLTEFERRL
                     SDIMVFYPCLVVEEEGGILGYAYASRFHARAAYAWSAEVTIYLAQEARGRGLGSALYH
                     RLEGYLKGMGILNCNACIASTAHATPYLTNSSQVFHEKLGYRLVGRFHQSGYKFNQWF
                     DMIWMEKLLGEHDVRPRPVMSFRDFLCQKHQSE"
     gene            2062..2388
                     /locus_tag="TVB59_000617"
                     /pseudo
     CDS             2062..2388
                     /locus_tag="TVB59_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419586.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin, lactococcin 972 family protein"
     gene            2457..4460
                     /locus_tag="TVB59_000618"
     CDS             2457..4460
                     /locus_tag="TVB59_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1009549.1"
                     /translation="MRWRATVICIFVLLLTCLSFGAVKEYGNDIKYPVQAAFSLVASN
                     KDVDKGHVLDRIEALAEQEHIQIYRPYLDHTGKEATYLFGTNGKKTVYSSNRKELLTN
                     DLSGMYYTTRSLPSSFETAMTERGLTYKGADLPWYLLPYYFLFTNLRSLAIWTLFFVF
                     ALLLFAVKLMYAKKSMILRSLGLFEHYSRKELLQDLLLMGASFAVSILLFILYQGSIS
                     NVFVKSFTLLILTNAVILLLLMLAVHALFFINIRSLKALAILKNKQATPLVLFVWLVG
                     ICLSSVIFGLSLHKSLETIGKSANDIQVLGKWDKAKDFAEITWLDTLSTHTDDNHQID
                     SDYFKEENQRYQHFLLSFSDNDVIYSALSSLNETNLQSAPDDFKKELKTNGVDPRIAS
                     KVRYVNQGFMLKNKDIFPNNDYGRPAADAVGVIYISKHMMGDADSILNIVNYEWFQYS
                     SLKANQLVVQEVPDGQKSFLFNHKQDQQDIFAQQEEVNTILVQLNFSFMTEPSLLTKF
                     GEMAQKSIYRQALIRDRLTQAGLTNFSSLTNVSNHLILERHKILSQLIGSVIALTVLA
                     IAQCFIIYEYIVSLMKQKAKKISVWFLMGQKSLVLIGRLLLPLALCLFLAIGMMGILT
                     GNRLMVLGIGLLYLGEIVCMSFFAYQAILKHRIQIIKGDFDIL"
     gene            4457..5065
                     /locus_tag="TVB59_000619"
     CDS             4457..5065
                     /locus_tag="TVB59_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1009550.1"
                     /translation="MIEIKQLSKHYGKKTIYDKLSLTFEANRSYALVGPSGSGKTTLL
                     NAIARLEKPDSGQILVNGQDIWSMKEQDYFKDYLGYVFQNYALIEEETVYDNLKMLAP
                     KSNIVEALHSVGLDSSFLSQNIYELSGGQAQRVAIARLLLKKACIILADEPTGALDKE
                     TGDEIIELLLSLVSPDTVLIFATHDPNVFSRVDDIIDICHLQ"
     gene            complement(5254..7980)
                     /locus_tag="TVB59_000620"
     CDS             complement(5254..7980)
                     /locus_tag="TVB59_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEL1009551.1"
                     /translation="MTPKKVHIISHSHWDREWYMAYEQHHMRLIQLIDDLLDLFKTDP
                     DFHSFHLDGQTIILDDYLQVKPGREAEIRQAIQAGKLRIGPFYILQDAFLTSSESNVR
                     NMLVGKEDCEQWGASVPLGYFPDTFGNMGQTPQLMRKAGLNAAAFGRGIRPTGFNNQV
                     DTSEKYSSQFSEMIWQGPDDSRILGLLFANWYSNGNEIPTEEKKARQFWDQKLADAER
                     FASTRHLLMMNGVDHQPVQLDVTKAIALANKLYPDYDFVHSCFEDYLADLSQELPEEL
                     SIVSGEMTSQETDGWYTLANTASARIYLKQANTRVSRQLENITEPLATMAFEVTGTYP
                     HDQLRYAWKTLMQNHPHDSICGCSVDSVHQEMMPRFDKAYEVGTYLAERSANQIAEAI
                     DTSMFPEDSCPFVLFNTCGHEKKTVSDLTLTWKIFPFGQRLPKAVYQEAKEYLETRQP
                     QFQVIDAAGRIIEEAEILGTDIAFDYALPERTFREAYFAIKVQLRLPLTLSAMSWQCL
                     ALKETDQPCQATDTDKMLFHQDRSCLENDFLKVIIAANGLLTIEDKLNGNRFDSCLQY
                     EDCGDIGNEYIFRQPDHDSPYLAHQGSCKLRVLTNTAYLAEIELTQTFDIPLATDDRL
                     KAEMEAVIDIRERQAKRSQEKAPFTVTTVIRMEKDSPRLQFQTSFNNQMTNHRLRVLF
                     PTHLKTDHHFADSIFETVKRPNHTNAQFWKNPTNPQHQEAFVSLFDGRTGVTVGNYGL
                     NEYEILPDTNTIAITLLRSVGELGDWGYFPTPDAQCLGQQTVSFSFESINATTRFASY
                     WRAQEAQVPVTMAQTKRHSGQLPAQYAYIKGATDHVALTAFKRRLSDNALITRSYNVS
                     NDKACALTLAIPDHTARVTSLLEEDQHEPLPAELGKGEILTLAWKKSESAHL"
     gene            complement(7995..9281)
                     /locus_tag="TVB59_000621"
     CDS             complement(7995..9281)
                     /locus_tag="TVB59_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEL1009552.1"
                     /translation="MTRPIPSSVLRFMDTIEELCGEEHRSWAINFKASFANTLETTLK
                     IDEDGTSFLLTGDIPAMWLRDSTAQLKPYLFLAKTDAGMRQIIAGLVKRQFRYICIDP
                     YANAFNEEENSKGHQADHTQMGPWIWERKYEIDSLCYPIQLAYLLYRETDCTEHFNED
                     FHRGIKLILDVWSTEQDHTASPYSFERDTWRKEDTLTHNGKGAPVAYTGMTWSGFRPS
                     DDACQYGYLVPSNMFAAVVLSYLEGLYTDLFKDQTIARRAHALRLAIQKGIEEHALVT
                     NSQGEIIYAYEVDGLGHYTIMDDANIPSLLAAPYLGFCAKDDPIYLATRQTILSPENP
                     YYYQGSAASGIGSSHTPPNYIWHIALALQGLTALDQKDKADILDLLVATDAGTHLMHE
                     GFDVNDPSHYTREWFSWANMMFCELLLDYLGFTISP"
     gene            9414..10472
                     /locus_tag="TVB59_000622"
     CDS             9414..10472
                     /locus_tag="TVB59_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1009553.1"
                     /translation="MTELLYKKIYHFIKEQIDSGQLQAGDRLPTEKALSEQFSVSRIT
                     SKRALVELEQEGLITRSRGKGSFVTDGPPPSTQPNKDILLILPFASDYELGDYAKGIM
                     TVVADKGYRLMVQLTSTVSLEELADYAGVIYYPEDVNHSIELLFYCAQRGLALVLLDK
                     ALDLFDFPAVVADNKGGAYELTKHLIDQDCRRIMFVATASFGEVSSVRDRYLGYLAAM
                     AETELEANYFVKLKSESNAAYLERLVDELTAATAEKTGLVVENDWLAIQLIQKILQVG
                     LSIPDQVAVVGFDNSQASQLISPQLTTAAQDFYQMGQQAAQLLIERLTRPDQQTASCQ
                     LPVKVFIRESSQKSLEML"
     gene            10487..12181
                     /locus_tag="TVB59_000623"
     CDS             10487..12181
                     /locus_tag="TVB59_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylglucosaminidase domain-containing
                     protein"
                     /protein_id="HEL1009554.1"
                     /translation="MSIYQALKDYQEVITRGDYLVFDAPVSCRFVGRFFRFENQTAMK
                     PSLTASVYVNWVEEGAADLTLKHVFNRTLARDAFTLTISEDKELVIESQNLRGFRYAQ
                     EALEKVMTVKEGRLYLPIVSVRHSPSFAMRGVIEGFYGTPWTREERLDCLSFIADKGM
                     NTYMYAPKNDDYQRSHWREPYPEDWVAHFRDLIQLAKERQVDFWYMISPGLDFDYTKE
                     EDYQLLYQKLQQLLDLGVCHFGLLLDDIDYQIVAAVERRFKKTAYAQAHLATAVYQFL
                     QRQHAAPDLVVCPTEYDNHHDSLYLAELSEAIPAEVAFFWTGPSTLASQISQADIETI
                     AAIYRRPIIIWDNIPVNDYQDDSKRLFLTPFANRSPFLCQPDYQVRGIVSNPMISWEL
                     SKPTLIDMSRYLWDAKRYQPSYSWLEALRDYTGDKAMALALLRFAWHNGNRHLHRDLP
                     FEVEEALMRKDIASLSGWVAELVELVDKLKELDIPAFQQAIAPWFDRAKADQSFWRVI
                     LEQAPDLEQQYAELQEQRHRIGSNIPSRFYQLHYLQENSMLGNQAQVAEARAEDYT"
     gene            12208..13599
                     /locus_tag="TVB59_000624"
     CDS             12208..13599
                     /locus_tag="TVB59_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEL1009555.1"
                     /translation="MLEFPEGFWWGSATSGPQSEGCFQKPHRNLFDYWYEQNPELFYD
                     YVGPDTASDFFHQYDQDLALLASLGHNSYRTSIQWTRLIDDFETATINPDGLAYYNRV
                     IDACLAHGMRPVINLHHFDLPIALYQKYGGWESKHVVDLFVAFARVCFEQFGDRVKDW
                     FVHNEPMVVVEGSYLLQFHYPAIVDGKKAVQVAYNLALATAKVICTYQEQAAELSNGS
                     VGTILNLTPIYPATDSEADLAAAHVAELWHNDLFMSAAVYGSFPKELVAILQRDGVLW
                     QSTPEELDLMAAYTVDYVGINFYRPKRVKAPEVIPVISPSWSPEWYYDAYLMPQRRMN
                     VDKGWEIYPEAVYDIALKMRDQYRNIPWFLSENGVGISGEDRYRDESGQIQDDYRIQF
                     LKEHLTYLHKGIQAGSNCFGYHVWTPINCWSWLNAYKNRYGLVENNHRTQRRRVKKSG
                     YWFKEVAEANGIS"
     gene            13586..13723
                     /locus_tag="TVB59_000625"
     CDS             13586..13723
                     /locus_tag="TVB59_000625"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009556.1"
                     /translation="MELAKKRRKTQKPAQSPLKLGLEKLREILQEQLVALAVLPARVM
                     G"
     gene            complement(13919..16093)
                     /locus_tag="TVB59_000626"
     CDS             complement(13919..16093)
                     /locus_tag="TVB59_000626"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEL1009557.1"
                     /translation="MDRLDFIDTRFGTTNHYHFSQGNCLPLTGVPFGMHYLSVETSQD
                     RGAWWFHPDDHSFSGIRLTHQPSPWVGDFATVTFLPVSGPLTKGDVFHNQTSYRPKEA
                     AFRPHLLEIFSQRHRILTRATAAAYSFHCDFSFDNGKAGLIIHNPGKSSWQVTADGKT
                     ILGCVQNITDCQDKDLAMFVYLQFSSPVLKKLIGEDLNSKSLDDCSKTSFTYLQFADD
                     LKHLELRAAASFISFDQAQLNWQRDFPRSFEKSLEYSRKEWLSYLSRIDIKDKDFDKV
                     KAYYQHFYRALLFPQRWYEITATGQAIHYNTTSQRPVAGKYYTNNGFWDTYKSVYPLL
                     SLIAPEIYADILEGLLSAYQDTNYLPKWLSPDERGLMPGTLVDAVIADGAVKGIRKDL
                     MPELLEAMLATANTDSQGTGYGRKGNQDYQELGYLPNSYQESVNQTQDYAYSDFCIGQ
                     VAALLGKTALSDQYHTRSLNYRHLVDTDTGYLKSKDRQGQWQCGFNPIHWGQDYTEGS
                     YYQNGFAFYHDILGYIRLIGGNAAIAKRLEELCNHEPVFDVHSYGFEIHEMSELAAQD
                     FGQIAISNQPSFHLPYLYHYIGQPQYSQLILKNLLSHAFTDTGYPGDEDNGSMSAWYL
                     LNSLGLYPVTPGTGQYLIGIPTVDQATLYLPNGNTIQISCRGNVPQYQFVKEVKLNQA
                     SYNKLYINHDDLIQGCQLDFQLGLVPPLKHYSAEDLPYSLTR"
     gene            complement(16081..16974)
                     /locus_tag="TVB59_000627"
     CDS             complement(16081..16974)
                     /locus_tag="TVB59_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEL1009558.1"
                     /translation="MTLLCIDIGGTSIKFAICHKGRLKKQSSRPTPQSLEDFYHMLDE
                     RLAYYRTEKLSGIAISSPGAVNKATGIIEGASALPYIHGFPIQQCLEERLGLPVSIEN
                     DANCAALAESALGAGQGTSSLAMLVLGTGVGGSLVINGRIHYGAHLFGGEFGFMVMNE
                     RYQTFSELGTVVNMAKRYSQIINDGKSYTGKEVLELADQGDPVALKERQVFLQSLAMG
                     VFNIQHAFDPEMILIGGGVSQADFLLPALEAELDKLYQIVSISDLRPQLAICHFKNEA
                     NLLGASIDFMQEHRKDEMWID"
     gene            17186..18136
                     /locus_tag="TVB59_000628"
     CDS             17186..18136
                     /locus_tag="TVB59_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004219264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1009559.1"
                     /translation="MTTKISSKKSFWKNVIKYRALLLMVLPGFVWFIFFFYIPVLANV
                     VAFKDFHYSAGGFMESLKESPWVGLDNFKYLFASKDAWLITRNTIAYNLIFLLFNVFF
                     AIAFAIIMSELRNKKAVKVYHTMSLLPYFLSWVVIEYFVSAFLNTDKGFINQLLIDSG
                     NSPIKWYSNPTWWPLILLFMSVWKGLGYNSIIYYASVKGISDTYYEAAMVDGASKWQQ
                     IRHITIPQLLPMMSILLIINIGSIFKSDFGLFYVIPKNSGPLYDVTSVLDTYVYNALT
                     ATGDISMASAASLYQSVVGTCILLITNAFVRRMDPDAALF"
     gene            18146..19072
                     /locus_tag="TVB59_000629"
     CDS             18146..19072
                     /locus_tag="TVB59_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEL1009560.1"
                     /translation="MEKKKTVKRVNVRTFDPKTNAVFNVLIALFAISCIIPFIFVMII
                     SFTDESYLINHGYSFFPAAWSTKAYHYIFQGAMSHRIIRSFAVSVFITVLGTFINTTM
                     TSTYAYAISRPYFPYRRFFTIYALITMLFAPGMVANYLVVSNLLQLKDTVWALILPMA
                     LGPFGILVMRTFFKKTVPDSIIESARMDGAGELMIFMKIVLPLAVPGIATISLFSALT
                     YWNDWFNALLYVQSESLYPMQYLLMKIQSNIQALAQNAGMSAQLSDSLASLPKESVRM
                     AIVVIATLPIALTYPFFQKYFVGGLTIGGVKE"
     gene            19156..20601
                     /locus_tag="TVB59_000630"
     CDS             19156..20601
                     /locus_tag="TVB59_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEL1009561.1"
                     /translation="MKKWQTILCVTGAVLAAASLTACGSKSASKDGEVKLLMYQVGDK
                     PDNFDELMTIANKRIKEKTGATLDLQYIGWGDWDDKMRIIIASGENYDIAFANNYVVN
                     AQKGAFADLTKLMPKYAKKTYKNLDPAYIKGNTIDGKLYAFPVDANVYAQQMLSFNKE
                     LVDKYGLDISNINSYADAEKVLKQFHEKEPNTAAFAIGQVFSMSGDYDYPLTKNQPFA
                     VKIDEGKPTIINQYEDEPFKANLRLMHKWYKEGLIPTDAATNTEGYPLEGNTWFMREE
                     TQGPMDYGDTILTNAAGKDIVSRPLTKPLKTTSQAQMANFVVSNVSKNKEKAVEVLSL
                     LNSDPELLNGLVYGVEGKAWEKVGDKKIKLLDGYQPKMHMGAWNTGNNKILYTQESIT
                     DDMIAKRDQSIKDAKESPILGFTVDTKAIKTELSKISNVMNRYKASINTGTVDPDEAL
                     PKLLSDLKDAGWDKVQKEVQKQLDDFVTKNK"
     gene            20949..21554
                     /locus_tag="TVB59_000631"
     CDS             20949..21554
                     /locus_tag="TVB59_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HEL1009562.1"
                     /translation="MTGIEKACFLIWKMMQLTLIFHLLSLCGAVIFGVGPAWQTIVTL
                     FLETSQQEKHYSLKRAFQIWRRVFKEANLSFFFFGLLLLLLNTSLYLAIQFQSLLWFS
                     LSFIIMFVMVWLVMIVIYMTFYAVTYEIAFWENLKLSFISIFLNARQFLLTLVVLAGV
                     AWFTWQYKGLYLFLSFGALVLLLDMVTKPNRRMVDGVIDDK"
     gene            21544..23268
                     /locus_tag="TVB59_000632"
     CDS             21544..23268
                     /locus_tag="TVB59_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL1009563.1"
                     /translation="MTSKSLKRFLMEHIKQGFLINRLMKIYSLFIVALFSLSAVGLST
                     YSIRNTYQMVDNQMQMRLDETLARLQSQNYITLRVLEQLIGRPEDYRNLYQYMILTPN
                     QYLTKVFEDWGEGKNTPLFSEQVRRLFDLYPDLDGLTLMLDDSTSYLYADRSIKTGRL
                     LFGKPQTLKGNYLVRSIRHPESGDVTGRLYLHFASPSTMLQPEQHKYLATFAFDYYGR
                     ELFHQGGAAFPELEAGLKKALKADQAIDLTALSKSYHIQYNRSGDLLAYVAVKRSYFM
                     EEAVRTMLLYGLGSLLLAWLLLQLLFRVFRNYIRQVSEITDTIEMVAAGDLSLRIDNS
                     HMELELYHISEAINQMLGNINAYILEIYVLEVEQRDAQMRALSSQINPHFLYNTLEYI
                     RMYALSCQQEELADVIYAFAALLRNNISQDKVTTLKEELAFCEKYIYLYQMRYPDSFA
                     YHVKLDPVVADVEIPKFIIQPLVENYFVHGIDYSRYDNALSIKALDEEDSILIQVLDN
                     GKGISPERLVAIEKGLEEPQSTGNSSIGLQNVYMRLFHKYRDRVTWSMSQAPTGGFRI
                     QIRIRKEA"
     gene            23268..24752
                     /locus_tag="TVB59_000633"
     CDS             23268..24752
                     /locus_tag="TVB59_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1009564.1"
                     /translation="MYKVLLVDDEYMILQGLKVIIDWQALGFEVVATARSAKEALAYL
                     DDCAVDVMISDVNMPGMTGLELIEAARDVLPHLQTLILSGYQEFSYVQRAMELETKGY
                     LLKPVDKKELVAKMLYFKEWLDEQRAASLRQAAYREGLINLWLADELSEKEFFQLTQE
                     QPEAELLGFTVLYVDCKTFSPALEAFFEASKQPFYLKKAEQKKVYLVILLGQSHQAKR
                     FTNTLQERFYNTINQIILGETVVDWENVYESYNQVRRSFFYNSEVSQVAAKTNAKIEL
                     PESRLQFFSFNKTLMIGDEPTIVSKLQAIFEEMTELSFSPEDVKHVSFLLFSDIYRQF
                     PILDRTTYLSMVKTIHDSQSIDQILSALKKVLELTSKSNQPQKRYSDLVSEAITCIQE
                     EYSQELTLKAVSDRLHINGVYLGQRFKNETECSFSQYLNQVRIQKAQQLLLYTNKSIN
                     EIAYETGYNTNHYFIKMFKKLNGLSPKEFRDRYKDNYQAIKGSY"
     gene            24766..28209
                     /locus_tag="TVB59_000634"
     CDS             24766..28209
                     /locus_tag="TVB59_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2 protein"
                     /protein_id="HEL1009565.1"
                     /translation="MSVETITGSTDQSHGDIYQLHWIDKVGRCHAFSKGWRFLMADLQ
                     LAQEPFFDDSDWQQIALPHDFSINQPYTVNGEAQSAYKLGGVGWYRKYFALDPKLADH
                     KVYVTFDGAYMETQVYLNGHLIGEHVNGYQAFSYDLSAFVIPGQENLLAVRVEHLVPS
                     SRWYSGSGLYREAFLTVLPKVHLDKDRLRLSLSQAALEADSQALEIELGLSQQVPLSG
                     YQLSLSLFEQLADIQQRQTVYESKPVALDLLEESGRLVMTIPLRHIKLWSPAQPQLYQ
                     LDMLLYHKGAVLDRLTLETGFRQLHFDAECGFFLNGKAFKLQGVCLHHDQGSLGACAY
                     EEAIARQLVLLKEMGANTVRVTHNPSARRLKDLANRLGLFLIEEAFDTWTYAKNGNSH
                     DFSSHFHKTVGHQNAARLKGVTTAETTWAQYSIQAMVLSGLHDPSVLMWSIGNELLEG
                     FSADVSHYPYVAKELCQWITELDQSRPITLGDNKLKDKHFHWAQETKALAEQVNQLQS
                     VQGVIGLNYAKARDYDRLHRDNPTWLLYGSETASAINSRGVYHLKGGASQDHELTSYD
                     QSTVDWGSLASEAWYDTITRDFVAGECVWTGFDYLGEPTPWNKIDSGAADQWPSPKQS
                     YFGILDTAGFAKDSYYFYQSQWSKDKTTLHILPSWQEKDLQLDDQGMVEVVVYSNAAS
                     VRILFDDGHGGQIDYGIKTLTRHETPAGHCYQLYEGDDAAELPHQNLYLTWKLPYRSG
                     SLRAIAYDDKGQVLTQTSGRSCVSSYQQPAQLSWSCFEPPKLLAEPALLYLELSLLDA
                     NETLVLSANPVIKLEVEGPGACLALDNGDPRDHRPYTALSRRAYGGKLLAIIALDGRA
                     GQLRITARAAGFVEASYQLTVSEAAVNEKLLAYQLDKYSFITNETNKPSKPYARSRGS
                     AVDSLMPNPDSCLKRQGHYLPDNSVMVFSYTTALSRPLTFQPLIKRLLKGNDIILPDW
                     LQPRAAAGQLFTKAFPIDWQLTEAVFSEESRVSGQTLCFGEALELEAILKSDTKGLRI
                     NQELSLVAKKKRLFQSDTQLSYRYQYDTIQAIGAISLTGLKKPLSSLRLVLDYRSSTN
                     APSKQLILSLDQIEQPCHYIMLEEVVDVLSLDLTLEQPIRQAFDLARLQLGLWSMVEE
                     A"
     gene            28360..29244
                     /locus_tag="TVB59_000635"
     CDS             28360..29244
                     /locus_tag="TVB59_000635"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEL1009566.1"
                     /translation="MLERLSGQTRLTALLAAPARHSLSPKMHNAAYAKLGLDYAYLAF
                     EVGNAELAAAVQGMRALGICGANVSMPNKQAIVPLLDELSPAAALAGAVNTVVNKDGR
                     GHLVGHITDGTGAIRALAEEGVSIKDQIITIAGAGGAGTAIAVQLGLDGAKEIRLFNR
                     KTATFKQAKQLVARINTQTSALASLQDLADDRAFRRSISESSIYIDATGVGMKPFEEH
                     RLITDPALIRPDLVVFDLVYHPAETKLLAFAREHGAKKVMNGLGMLLYQGAEAFKLMT
                     GEDMPVAYIRELLCQNKE"
     gene            29370..30143
                     /locus_tag="TVB59_000636"
     CDS             29370..30143
                     /locus_tag="TVB59_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEL1009567.1"
                     /translation="MILTQFDPDYQAIINPKDLVAEIDDFPKTVVTCFARATFNRVLN
                     ALPHRLIATTSVANLDIPIYELDVKGHKLGFFNSYVGAAGCVGVLEDIIAMGMKQLLV
                     FGTCGVLDATISENSIIIPTSAIRDEGTSYHYQPASHDIAVNQAYLTRAIDVLEQHSQ
                     TYTLGKTWTTDGIYRETRDKMIQRKQEGAICVDMECSAIAALAAFRQLEHFQFFYSAD
                     NLDADEWDARSLANEADLEAKDNIAFIALELALRLFKDN"
     gene            complement(30475..31557)
                     /locus_tag="TVB59_000637"
     CDS             complement(30475..31557)
                     /locus_tag="TVB59_000637"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEL1009568.1"
                     /translation="MTQTLQVKSRINDYPIIFTDDIFQPLNQFLAEKGDVKLLFITDQ
                     TVFDLYQPLFRRFQQDYDSYLHIAAPGGQSKSLEEVSRIYDRLIRANFSKKDVIVTVG
                     GGVIGDLGGFVAATFYRGISYVQIPTTLLSQVDSSIGGKVGVHFKGLTNMIGSIYPPN
                     QIIVSAKFLDTLSEREFACGISEMIKIGFIHDRKLFQQLLAFPKDRNQEQLRQMIFQA
                     ICHKKRVVEKDEFEGNLRMSLNFGHTLGHAIEALCHHELYRHGEAIAIGMVFEAKLAV
                     QQQLLSQQDLEALQAAFEAYQLPTTLEAKSMTAEALMTVLKTDKKNSGQHIVLILPTT
                     KGYVSFPIAKHDSRLLDWLRSLLDIA"
     gene            complement(31616..32371)
                     /locus_tag="TVB59_000638"
     CDS             complement(31616..32371)
                     /locus_tag="TVB59_000638"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEL1009569.1"
                     /translation="MGNDIIADFLNKGCQKSNFIVGPCAIESYQQIRQAAASAKALGY
                     RYFRGGAYKPRTSSNSFQGLGLTGVTYLHEVCQEFSLKAVSEIMSERQLEEAYDYLDI
                     IQIGARNMQNFELLKVLSKIDKPILFKRGLMATIEEYLGALSYLQENGKQNIILCERG
                     VRGYDVETRNMLDIMAVPIIQQKVKLPIIVDVSHSTGRRDLLLPAAKAAKAIGANGIM
                     MEVHPTPDLALSDAAQQIDYQQLEQLGKELWES"
     gene            32809..32979
                     /locus_tag="TVB59_000639"
     CDS             32809..32979
                     /locus_tag="TVB59_000639"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009570.1"
                     /translation="MLRYLKAILYLLAPRLAFSVTGVLFPDVFDNLFLVYNILMTLAF
                     WLAIYSVDLPEK"
     gene            33886..33956
                     /locus_tag="TVB59_000640"
     tRNA            33886..33956
                     /locus_tag="TVB59_000640"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:33918..33920,aa:Thr,seq:ggt)
     gene            34484..34738
                     /locus_tag="TVB59_000641"
     CDS             34484..34738
                     /locus_tag="TVB59_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEL1009571.1"
                     /translation="MSYEQDFLRDFEDWVKAQIQVNQLAMATSRQIAKEDNDQRARDA
                     FIRYESKLDAYEFLLGKFDNYNKGKAFHEVPDSLFGSRHY"
     gene            34760..35260
                     /locus_tag="TVB59_000642"
     CDS             34760..35260
                     /locus_tag="TVB59_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1009572.1"
                     /translation="MARRYNRKKQYKLQLKRQGLLKAVINQVEQTVEKVVDKTKEAVH
                     TASQMVTASKTETADLQDKQSIAEKAAQPKADVASSSLADSSEVSSEKEASKASSEVL
                     SRDAFAELAEVSELRADIVTVLFEAGIRSAAAFSQWTEAELLALKGIGPATISKLKEN
                     GVNFKK"
     gene            35520..36104
                     /locus_tag="TVB59_000643"
     CDS             35520..36104
                     /locus_tag="TVB59_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1009573.1"
                     /translation="MIEIMGSVENNRLPDVKTSRLLLRQRTLADVEAIFAYASRPEVS
                     YPAGFPPVKTLEEEEHYIANTMPKRWLLQQLPAGYGIALKGDNRIIGSVDFNNRHADD
                     VFEMGYLLHPDYWHQGIMTEAASALLEVAFTLLKLHKVEISCYDYNMGSRRIAEKLDF
                     TLEATIRDRKDAKGNRCADLRYGLLKREWERQCR"
     gene            36304..36867
                     /locus_tag="TVB59_000644"
     CDS             36304..36867
                     /locus_tag="TVB59_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEL1009574.1"
                     /translation="MNIILIGAQASGKMTIGQELEKLTDLTLFHNHESIDFVTKFIPM
                     SSEARELIDELRLLFFKTFAKRQQSIIFTVVIDFNAPEDIAFLETLQSVFHDFDREVL
                     FVELEIDLKERLRRNKTENRLYHKPIKRHLEWSEKDILDTAKFANFNPAKVPENLKYY
                     CKINNTSLSAQETAQFIVQKMKELEVS"
     gene            36880..39531
                     /locus_tag="TVB59_000645"
     CDS             36880..39531
                     /locus_tag="TVB59_000645"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEL1009575.1"
                     /translation="MSKELSPKYNPAEVEAGRYQAWLDQDVFKPSGDKKAKPYAIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLREQG
                     ISRYDLGRDKFLDKVWEWKDEYAATIKEQWGKLGLSLDYARDRFTLDEGLSKAVRKVF
                     VELYKKGWIYRGEFIINWDSAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALQVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGQHVVLPIVNKLIPIVGDEHADPAFGTGVVKIT
                     PAHDPNDFEVGGRHNLPQVNVMNDDGTMNELAGEFAGMDRFEARKAVVAKLEEIGALV
                     EIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTDDKVDFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNEAGDMYVGEEAPAGDGWKQDEDVLDTWFSS
                     ALWPFSTMGWPDVDSEDFQRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRKPFSNVL
                     IHGLIRDEEGRKMSKSLGNGIDPMDVIEKYGADSLRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNEGLTLEQASANVEQVASGAAGNVTDCWILHNLNETIGKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDEKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQYAEGSIVTADYPTVDPAFENEAAHKGVESLKDLIRTVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPERLKIASSIVTPELAMSA
                     VITGAEIFLPLADLLNVTEELARLEKELAKWQKELDLVSKKLSNERFVANAKPEVVQK
                     ERDKQADYQAKYDATVERIKEMEKLVR"
     gene            39744..40232
                     /locus_tag="TVB59_000646"
     CDS             39744..40232
                     /locus_tag="TVB59_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013642832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase"
                     /protein_id="HEL1009576.1"
                     /translation="MTTAATKASVPHKEKMESKEPETSHQPEAYPDLASYQELAVHVS
                     IADQVMTIIGDGKVIFKTSVSTGAKESPTPTGTFVIEPERGDFFFNQASEEGAYYWVS
                     FKDHGIYLFHSLPTDQYGNEIPEEAERLGQPASHGCVRMSRADAKWFYDNIPEGISVT
                     IE"
     gene            complement(40435..41235)
                     /locus_tag="TVB59_000647"
     CDS             complement(40435..41235)
                     /locus_tag="TVB59_000647"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009577.1"
                     /translation="MKKKLVMSLIVNLPLLSLICFNEVSANSDYENSPVLGQGYYGYD
                     DYTEAPQIGDQKVIGFRRDWENARDFGVKPIKNNDKEIVVKTSPGSLIRIFKVEEDDK
                     ETELVQVQKKSNGDLTNNRYYPIAKWDGKIVFSLESARTQKTNSKEETYVPYNKIASN
                     GDKFRVHITSDGFVLGSEIWIVGESKPQDIIEQEQKKAQKELEEQKKQENLRQQIKKE
                     REHSQKRVVENIYLKEIRENAHKSWHKRLNEKIQEQWSKFTVFLNKYY"
     gene            41746..41982
                     /locus_tag="TVB59_000648"
     CDS             41746..41982
                     /locus_tag="TVB59_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEL1009578.1"
                     /translation="MTFEEILPGLKAKKKYVRKGWGGAENYVQLFDSIEQNGVALEVT
                     PYFLINVSGAGEGFSMWAPTPCDVLATDWVEVYD"
     gene            41975..42673
                     /locus_tag="TVB59_000649"
     CDS             41975..42673
                     /locus_tag="TVB59_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEL1009579.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLRNGFTVYGVDKAKKPDLSGDF
                     QFLQLDITGDLAELFEAVPRVDVLCHTAGVLDAYKPLLDTTQADFEALFQVNFFAAVR
                     ITRHYLAQMLTAQSGIIINMCSIASFMAGGGGAAYTSSKHALAGFTRQLALDYAKAGI
                     QVFGIAPGAVQTAMTATDFEPGGLAQWVADETPIGRWLRAEEIAELTMFLASGKASAM
                     QGEIVKIDGGWSLK"
     gene            42873..43331
                     /locus_tag="TVB59_000650"
                     /pseudo
     CDS             42873..43331
                     /locus_tag="TVB59_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623303.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
     gene            43332..44306
                     /locus_tag="TVB59_000651"
     CDS             43332..44306
                     /locus_tag="TVB59_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEL1009580.1"
                     /translation="MKLALVGTGMIVKEVLPVLKEIKSIDLMAIVSTPRSLETAEALA
                     DAFGIQQASCQLAEVLKNEEVDTVYVATPNHLHFEVAKQALEAGKHVICEKPFTMTAK
                     ELDALSSIARAKQLILLEAITNQYLPNTQFIKDHLTELGEIKLVECNYSQYSSRYDAF
                     KRGEIAPAFDPKKGGGALRDLNIYNIHLLVGLFGKPQTVQYLANMERQVDTSGVLLMD
                     YERFKAVCIGAKDCSAEIVSTIQGNKGFLSVLGAPNAVPELLLAIRGEQARTVNFNHP
                     SHRMYDEFIAFSDIISNKDMERAEQALEHSKAVMAVLEQAAASLESDS"
BASE COUNT        12280 a         8909 c        10445 g        13031 t
ORIGIN      
        1 gaaaggagtg ctttcaaatg ttatcagggg agcatgatgg ctaaagagag acctcagagg
       61 aaactcagtc tttgaagcat taagacagct ttctcatatt ggttacgggt attagaaatg
      121 cgcttaatcg gtgtcaacag ttttcgtatt accatttaag acgtttcgac gacattttaa
      181 gacttaaata ctgaaagcag ctggtaatat gctatactgg tgccagttgc taaacatagg
      241 aaatattcat gtggacgaca gcattgatga aatatttaat gcttaggtac tggtagactt
      301 gcttatgttg aggctgaaaa aattaataga gtttgtgacg cagctattgg aggaataggt
      361 ggcgcactga cttgctaaga aagggcaagg tgttgtaatg cttaataaaa tgaagcgact
      421 acattatttg atgattttta ggctattaac tggtcagcta ccagctatta gcttgatggc
      481 tgttcttctt tcaaaagaca ttcataggct ttctttggga tcactgatta gttttgctat
      541 ctttgcggta agcactgctg cttctaatta ctatttttca cgagaaattg cgattgagca
      601 gttgaaggaa caaacacgtc ccaatctgtt attaactcag atcctgttta tagtggtgtt
      661 tatgattata ggcattgtgt caatctattg tggtctaagc tcgtctgagt tttataagca
      721 ggttattgct gtgatatgct cttttatatc atttgtcact atgggattga tgatttgggg
      781 gatcagatac gcaaaagctt atcgtcgtta atagcttgag gtggtactgg tacttgaaat
      841 cacctcctta accagttaat cataagctat agcactaggt atcagcctta aagcgacgat
      901 acctagtgtt tgtgtgctca aacgcttaaa atagcttttg agggggtaga gctgtctatc
      961 tgcaagcgat atgacaacct atttcattta gggatcaggc ttttttacta tcagtgtttt
     1021 tgacaaggcc cttgttttgg agtatactgg gaaaactagg agggctatta atgcgtagga
     1081 ttcgtttagc aaccttagca gatgctaagg ctttacttga tatttaccgt ccttatgttg
     1141 aggaaaccgc tgttaccttc gagtacactg tacctagctt gaccgagttt gagcgacgtc
     1201 tgtctgacat tatggtcttt tatccctgtc tagtagtgga agaggaggga ggcattttag
     1261 gttatgccta tgctagtcgc tttcatgcac gcgcagccta tgcttggtct gctgaggtga
     1321 ccatttatct ggcccaggag gctagaggga gaggcttggg atcagccttg tatcaccgtt
     1381 tggagggtta tctgaaaggt atgggaatct taaattgtaa tgcctgtatc gctagtacag
     1441 cgcatgctac gccttatctg accaatagca gtcaagtctt ccatgaaaaa ctcggttatc
     1501 ggttggttgg cagatttcat cagtcgggct ataagtttaa ccagtggttt gatatgattt
     1561 ggatggagaa actgctggga gagcatgacg tacgccctcg cccagtgatg tcatttaggg
     1621 attttctttg ccagaagcac cagtctgaat gacaccttat aaaagcttag attaatacaa
     1681 aaggattagg tcctgtcaga ggaagctaat ttttttgtat tgtttgacga gaagttttga
     1741 ctgataaccg caatcataaa aaaactcttc aggccctgtt ataaaatggt ggtagcagga
     1801 gatggttatg tctgagcttg tcactaggtc agctacagca gtcctagtgt catagcttta
     1861 aaaatgagaa aaaagaaatt attttttaag cttggtcttt ttaatatctt tttttgccct
     1921 tgacaattct gccaatgagc tgcaaaaaaa cttaagctct ttcccaaaaa gcttttatga
     1981 tatgatacac ttgtgttgta aaaggatcct gatactagtt aagatttttt tactttattt
     2041 taacaaagga gagtacacga catgaaaaga agtgtaaaat ggtttatgag ccttggcttg
     2101 gttggagctt tcgtagttgc tgggatatct aatgttaacg cagagactag gcaccctcat
     2161 ccaaagtata aggacacttg ggaatttgga attaccagtg ctagctgatc ttactcaaac
     2221 gcttttcttg gagttcctat tgggctagga agtagtgctt ctgtgacaga cttttgggga
     2281 aatgtaaata gtaaagatag tcaaaacaat ggttgggctc gtgccggtgt aaaaaagcag
     2341 tggaattggg ttcaagcaaa gtcatgttat ggctggtatc aggtttaatg ttttattgta
     2401 cgttttagtg gatgaagata ttatcctctt agtcaacttt tctcaaggag gtttttatga
     2461 ggtggagagc tacagttatc tgtattttcg ttctgctttt gacatgttta tcatttggtg
     2521 cggtcaagga gtatggcaat gatatcaaat accctgttca ggctgcattt tcattagtgg
     2581 cttcaaacaa agatgttgat aagggacacg ttttagacag gatcgaagcc ttagccgagc
     2641 aggaacatat ccaaatttat cgtccctact tagatcatac tggtaaagaa gccacctacc
     2701 tgtttgggac aaatgggaaa aagactgtct atagcagtaa tcgcaaggag ctcttgacaa
     2761 acgatcttag tggcatgtac tacacgacga ggtctcttcc ttcatcattt gaaaccgcga
     2821 tgactgaacg gggcttgacc tacaaaggtg ctgatttacc ttggtatctc ttgccttatt
     2881 attttttgtt cacaaactta cgatccttag ctatttggac cctctttttt gtgtttgccc
     2941 tcctcttgtt tgctgttaaa ttgatgtatg ctaaaaagtc tatgatacta agaagcctgg
     3001 gcttatttga acactatagc cgcaaggagt tgctacagga tttgttgctg atgggagcta
     3061 gctttgcggt tagtattctc ctcttcattc tctatcaagg cagtatctcc aatgtttttg
     3121 tcaagtcatt tacacttctg atcttgacta atgctgtcat tttattattg ctgatgcttg
     3181 ctgttcatgc tttatttttc atcaatatcc gttcgttgaa ggcgctagcc attctaaaaa
     3241 ataaacaagc aacccctttg gtcctctttg tctggttggt ggggatttgt ttgtctagcg
     3301 tcatttttgg gctttcccta cacaaaagct tggagactat aggaaaatct gccaatgaca
     3361 ttcaagttct aggaaaatgg gataaagcta aggattttgc ggaaataaca tggctagata
     3421 ccttgagtac gcatactgat gacaatcacc aaattgatag tgattatttc aaggaagaaa
     3481 atcagcgcta tcaacatttt ctcctgtctt tttctgataa tgacgttatt tattcagcac
     3541 tttcaagcct taacgaaacc aatttacaat cagctcctga tgacttcaaa aaagagttaa
     3601 agaccaatgg ggttgatcca aggattgcgt caaaagtccg ttatgtcaat cagggattta
     3661 tgctaaaaaa taaagacatt ttccctaaca atgattacgg aaggccagca gctgatgctg
     3721 taggagtcat ttatatttct aaacatatga tgggagatgc tgacagcatt ttaaacattg
     3781 tcaattatga atggtttcaa tatagcagcc taaaggctaa tcaattggtt gttcaagagg
     3841 ttcctgacgg acaaaagagc tttctgttta atcataagca agaccaacaa gacatttttg
     3901 ctcagcaaga agaagtgaat actatattag tgcagttaaa cttttcgttc atgacggagc
     3961 catcattatt gacgaagttt ggagaaatgg ctcaaaaatc tatctatcgt caggcgctta
     4021 ttcgtgatcg attaacacaa gcaggcttga cgaatttctc tagtttgacc aatgtttcca
     4081 atcatttgat tttagagcgc cataaaatcc taagccagct catcggaagt gttattgcct
     4141 taacggtcct tgccattgcc cagtgcttta tcatttatga atacattgtt tctctgatga
     4201 aacaaaaggc caaaaagatt tccgtctggt tcttgatggg gcaaaaaagc cttgttttga
     4261 ttggtagatt gttattgccc ttagctttgt gtttgtttct tgccatagga atgatgggaa
     4321 tccttactgg aaataggctc atggtactag gcattggcct gctttattta ggagaaatcg
     4381 tttgtatgtc cttttttgct tatcaggcta ttttgaagca tcggattcaa atcatcaaag
     4441 gagattttga catattatga ttgagataaa acagctttcc aaacattatg gaaaaaagac
     4501 aatttatgac aagcttagct tgacttttga ggccaatcgt tcttatgcac ttgtaggtcc
     4561 ttcaggatca ggcaagacca ccctattaaa tgctattgct cgccttgaaa agccagatag
     4621 tggtcagatt ttagtaaatg gtcaagacat ttggagcatg aaagagcaag attattttaa
     4681 ggattatttg ggctatgttt ttcaaaatta tgcactgata gaggaagaaa cagtctatga
     4741 caatcttaaa atgctggctc ctaaatctaa cattgtggaa gccttgcata gcgttggctt
     4801 agacagtagt tttctctcac agaacattta tgaattatca ggtggtcagg ctcagcgtgt
     4861 tgctattgca cgcctattgt taaaaaaggc ttgcattatt ttggcagatg agccaacggg
     4921 tgccttggac aaggaaacag gtgatgagat tattgagctg ttgcttagtt tggtgagccc
     4981 tgatactgtt ctgatttttg ccactcatga cccaaatgtg tttagccgcg ttgatgacat
     5041 catcgacatc tgtcatctac aatagaggca agctctgaga catttagtct ggactgtcga
     5101 gctacagcaa ttagcttgac aatgctgtta ttcctttgtg tcaggaagag attgctattc
     5161 ttctatagat ttttcgaata gacaatgctg aaagtcctta gcgttaatgc taaggacttt
     5221 tttgtgattt aggtcaaggt agtggtaatc tggttataga tgagctgatt cactcttttt
     5281 ccaagctagg gttaggattt cgcccttgcc aagctcagct ggtaggggtt catgctgatc
     5341 ctcttctagt aggctggtaa cccttgctgt gtggtctggg attgctaggg taagagcgca
     5401 ggccttgtca tttgatacat tatagctgcg cgtgattagg gcattatcgg ataggcgacg
     5461 cttgaaggct gtgagagcaa cgtgatcagt tgctcctttg atgtaagcat attgagctgg
     5521 cagctggcca gaatgcctct tggtttgcgc catggtgact ggtacctgag cctcctgagc
     5581 tcgccaatag ctggcaaagc gtgtggtagc gttaatgctt tcaaagctaa agctgacagt
     5641 ctgttgaccg aggcattgag catcaggggt tgggaagtag ccccaatctc caagctcacc
     5701 gacgcttcgt aggagcgtga tagcgatggt attggtatct ggtaggattt cgtattcatt
     5761 gaggccgtaa ttgcctacag tgacaccagt cctaccatca aaaaggctga caaaggcctc
     5821 ctgatgctga ggattggttg ggtttttcca gaattgggca ttggtatgat taggccgctt
     5881 tacggtttca aaaatactat ctgcaaaatg gtggtctgtc tttaaatggg ttggaaatag
     5941 cacgcgcaag cggtggtttg tcatttgatt gttaaagctg gtctgaaatt gtaggcgtgg
     6001 gctgtctttt tccatacgaa taactgttgt tactgtaaag ggcgcttttt cctgtgagcg
     6061 tttggcctga cgctctctaa tgtcaatgac agcctccatt tcagccttta gacgatcatc
     6121 tgtagctaag ggaatatcaa aggtctgtgt caattcgatt tcagcaagat aggctgtgtt
     6181 ggtcaagacc cgcaacttac agctcccttg atgagcaagg taggggctat catgatctgg
     6241 ctggcgaaag atatattcgt taccaatatc accacaatcc tcgtattgga gacagctgtc
     6301 aaacctattg ccatttagct tgtcttcaat cgttagaagg ccatttgctg cgatgatgac
     6361 ttttaggaaa tcattttcaa gacagctcct gtcctgatga aagagcattt tgtcagtgtc
     6421 agttgcttgg caaggctgat cagtctcttt tagtgcaaga cattgccatg acatagcaga
     6481 aagagtcagt gggagcctta gctgtacctt gatggcaaag taggcttctc tgaaggtgcg
     6541 ctctggcagg gcataatcaa aggcgatgtc tgtgcctaag atttcagcct cctctatgat
     6601 cctgccagct gcgtcaataa cctgaaattg tggctgtctt gtctctaggt attcctttgc
     6661 ttcttgataa acagctttag gcagtcgttg cccaaatgga aaaatcttcc atgtcagggt
     6721 gaggtcggag accgtttttt tctcatgacc gcaggtattg aagaggacaa aaggacagct
     6781 atcctctgga aacatggagg tatcaatagc ctcagctatt tggttggcag aacgctctgc
     6841 taagtaagtc cccacctcat aggctttatc aaagcgaggc atcatctcct ggtggacact
     6901 atcaacacta cagccacaaa tggagtcatg agggtggttt tgcatcaatg ttttccaagc
     6961 atagcgcagc tggtcgtgag gataggtacc tgtgacctca aaggccatcg tggcaagagg
     7021 ctctgtgata ttttcaagct gacgagacac tctggtatta gcctgcttga ggtaaattct
     7081 agcagaggca gtgttggcta aggtatacca gccgtccgtt tcttggctgg tcatctcacc
     7141 agacacaatt gagagctcct caggcagctc ctgacttaaa tcagccaaat agtcctcaaa
     7201 gcaagagtgg acaaagtcgt aatcagggta gagcttattt gcaagggcaa ttgccttggt
     7261 aacgtctagt tgaacaggct ggtgatcaac cccattcatc atcagcaggt gcctggtaga
     7321 agcaaagcgc tcagcgtctg ctagcttttg atcccagaat tgtcgagcct ttttctcctc
     7381 ggttgggatt tcgttgccat tgctgtacca attggcaaat aataagccga gaatgcggct
     7441 atcatcaggt ccctgccaga tcatttcaga aaattgggag ctgtattttt cgcttgtatc
     7501 cacttgattg ttaaagcctg taggcctgat accacgtcca aaggcagcgg catttagccc
     7561 tgcttttcgc attagctgtg gtgtttgtcc catatttccg aaggtgtctg gaaaataacc
     7621 cagtggaacg cttgcccccc attgctcaca gtcctctttg ccaaccagca tgtttcggac
     7681 attggactca ctgctggtca aaaaggcgtc ctgtaggata taaaaggggc caatacgtag
     7741 cttaccagcc tgaatggcct gtctaatctc ggcctcacgc ccaggcttga cctgcaaata
     7801 gtcatctagg ataatggttt gcccatctag atggaagcta tgaaaatcag ggtctgtttt
     7861 aaaaaggtct agtaaatcgt caattaactg gatcaagcgc atgtggtgct gctcataagc
     7921 catgtaccat tcgcgatccc aatggctgtg tgaaatgata tgtacttttt taggtgtcat
     7981 cactgactca ctttctaagg gctaatggta aagcccagat aatcaagaag aagctcacaa
     8041 aacatcatgt ttgcccatga gaaccattca cgtgtatagt gactcggatc attgacgtca
     8101 aagccctcat gcatcaggtg ggtgcctgcg tcagtagcca ccagtaaatc aagtatatct
     8161 gctttatctt tttgatcaag tgcagttaag ccctgaaggg caagtgcaat atgccaaata
     8221 tagtttggtg gcgtgtggga ggagccaata ccagaagcag cactgccttg gtaataataa
     8281 ggattttccg ggcttaaaat ggtttgacga gtggctaggt aaatagggtc gtccttggca
     8341 caaaagccaa gatagggtgc cgcaaggagg cttggaatgt tagcgtcgtc catgatagta
     8401 tagtgcccca ggccatctac ctcataggca tagatgatct ctccttggct gttggttaca
     8461 agagcatgct cctcaatccc tttttgaatg gcaagcctaa gtgcatgagc tctcctagca
     8521 atcgtttgat ccttaaagag atcagtatag agcccttcaa gataggataa gacgacagca
     8581 gcaaacatgt tggacggcac gaggtagccg tattggcagg catcatcgct tggtctaaag
     8641 ccagaccaag tcatgcctgt ataggcaaca ggagctccct taccgttgtg ggtcaaggta
     8701 tcctccttac gccaggtgtc gcgctcaaag ctgtaaggag aggcagtgtg gtcttgctct
     8761 gtgctccaga catcaaggat cagcttgatt cctctgtgga aatcctcatt gaaatgctct
     8821 gtacagtctg tctctcggta gagcagatag gctaactgga tcggatagca gagggaatca
     8881 atctcatatt ttcgttccca aatccaaggt cccatctggg tgtggtctgc ttggtggccc
     8941 ttgctatttt cctcctcgtt aaaggcgttg gcataggggt caatgcaaat gtaacggaac
     9001 tgacgtttaa cgagacctgc tatgatttgt ctcatgccag catctgtctt ggctaaaaag
     9061 agataaggct ttagttgcgc agttgaatca cgcagccaca tggcaggaat atcacccgtt
     9121 agaagaaagc tggtcccatc ttcgtcgatt tttagggtcg tttccaaggt gttggcaaag
     9181 ctggctttaa aattaatggc ccagctacgg tgctcttcac cgcagagctc ttcaatcgtg
     9241 tccataaacc tgagcacact gctaggaata ggtcttgtca tatcatatcc tcctaaaaga
     9301 tatatcattt gatatctttt ttaattataa gatataactt tatttttgtc taccacttta
     9361 gaaaaggttt acaagtcttt tttttcgtga tatactgcta gagggagtaa aaaatgactg
     9421 aattactata taaaaagata tatcatttta tcaaggaaca aattgattca gggcaattac
     9481 aggcaggtga ccgcctacca acagaaaagg ccctatcaga gcaattttcg gtgagccgca
     9541 ttacctctaa gcgagcctta gtagagctgg agcaagaggg cttgattaca cgcagcagag
     9601 gtaagggcag ctttgtgacc gatggcccac caccgtctac tcagcctaat aaggacattt
     9661 tgttgatcct gccctttgct tctgattacg aattgggaga ttatgctaaa ggaatcatga
     9721 cggtcgttgc tgacaaaggc tatcgcctga tggtccagct tacaagtacg gtaagcttgg
     9781 aggagctagc tgattatgct ggtgtgattt attatccaga agacgttaat catagtattg
     9841 agctgctctt ttattgtgcc cagcgtgggc ttgctctggt gcttttggat aaggccttag
     9901 acctgtttga ctttccagca gttgttgcag acaataaggg cggagcctat gagttgacca
     9961 agcatttgat tgatcaggat tgccgtcgga tcatgtttgt ggcaactgct tcctttggtg
    10021 aggtttcctc tgttagagat cgttatttgg gttatttggc tgcgatggcg gaaacagagc
    10081 ttgaggccaa ttattttgtg aagctgaagt cagaaagcaa tgctgcttat cttgagcgat
    10141 tggttgatga gctgacggct gctacagctg aaaagactgg tttagtggtt gaaaatgatt
    10201 ggctagccat tcaattgatc caaaaaattc tacaggtcgg gctatctatt cctgatcagg
    10261 tagctgttgt tggctttgac aacagccaag cctctcagtt aatcagccct caattgacaa
    10321 cagctgcaca ggatttttac cagatggggc agcaagcagc gcaactattg atagagcggc
    10381 tgactcggcc tgatcagcag acggcgtctt gtcagcttcc tgttaaggtc tttatcagag
    10441 aaagcagtca aaagtcccta gaaatgctat aaaaaggaga agtgtcatgt ctatttatca
    10501 agccctcaag gactatcagg aggtgataac cagaggtgat tacctcgttt ttgacgcccc
    10561 tgtttcctgt cgctttgttg gtcgtttttt ccgatttgag aaccaaacag ctatgaagcc
    10621 tagtcttaca gcgtcagtct atgtcaactg ggttgaggag ggagcagctg acttgaccct
    10681 taagcacgtt tttaaccgca ccttagctag ggatgccttt accttgacca tttcagagga
    10741 taaggagctt gtgattgaaa gccaaaattt aagaggcttt cgctatgctc aggaggcttt
    10801 agaaaaggta atgactgtta aagagggcag gctttatttg ccgattgttt cggttaggca
    10861 tagtccgtcc tttgccatgc gtggtgtgat tgaaggcttt tatggcaccc cttggacgcg
    10921 tgaggagcgt ttagattgct tgagctttat tgctgataag ggcatgaata cctacatgta
    10981 tgcccctaaa aatgatgact atcagcgcag ccactggcgt gagccctatc cagaggattg
    11041 ggtggctcat tttagggatc tgatccagct tgccaaggaa agacaggttg acttttggta
    11101 catgattagt ccggggcttg attttgacta caccaaggaa gaggactatc agctgctcta
    11161 tcaaaaattg cagcaattgt tggatttggg tgtttgtcat tttggcctgc tgcttgatga
    11221 tattgattac caaatagtgg cagcagttga gagacgtttc aaaaaaacag cctatgccca
    11281 agcacatttg gcaacagctg tttaccagtt tttacagcgg cagcatgcag cccctgactt
    11341 ggttgtctgt ccgacagagt atgataatca tcatgactct ctttatttag cagagttatc
    11401 agaggctatt cctgctgagg tggctttttt ctggactggc ccaagcactc tggccagtca
    11461 gatttctcag gcagatattg agacaatagc agccatctac cggcggccca taatcatctg
    11521 ggataatatc cctgtcaatg attatcagga cgattctaag aggctctttt tgaccccgtt
    11581 tgccaatcgc tctcctttct tgtgtcagcc agactatcag gtcaggggga ttgtgtctaa
    11641 tccaatgatt agctgggaac tatcaaagcc gactttaatt gatatgagtc gctacctgtg
    11701 ggacgccaag cgttatcagc caagctattc ttggctagag gccttgagag actatactgg
    11761 agataaggct atggctttag cgcttttgcg ctttgcttgg cataatggca atcgtcattt
    11821 gcacagggat ctcccctttg aggtggagga ggcccttatg cgtaaggaca tagctagctt
    11881 atctggttgg gtagctgagc tggtagagct ggtggataag ctgaaagagc ttgatattcc
    11941 tgcgtttcaa caggctattg ctccttggtt tgatcgggct aaggctgatc agagcttttg
    12001 gagggttatt ttagagcaag cgcctgatct tgagcagcaa tatgctgagc ttcaggagca
    12061 aaggcatcga attggaagca atattccaag ccgcttttat cagttgcact atcttcagga
    12121 gaatagcatg ctaggcaatc aggcacaggt cgctgaagct agagctgagg attatactta
    12181 attagtttat aagggagaac aagggacatg ctagagtttc cagaaggatt ttggtgggga
    12241 agtgctacat caggccctca aagtgaaggc tgctttcaaa agccgcatcg caatttattt
    12301 gattattggt atgagcaaaa tcctgagctg ttttatgatt atgttggacc tgatacggct
    12361 tctgattttt ttcatcagta tgatcaagac ctagctttat tagcgtcttt gggtcacaat
    12421 tcctatcgga cctctatcca gtggacacgc ttaattgatg attttgagac agccacgatc
    12481 aatcccgatg gactggctta ctataacagg gtgattgatg cctgcctagc acatggtatg
    12541 cgtccggtga tcaatttgca ccattttgat ttgccaattg ctctttatca gaaatatggc
    12601 ggttgggaat caaagcatgt tgtggatttg tttgttgcct ttgctagagt atgctttgag
    12661 cagtttggcg atcgcgttaa ggattggttt gtacacaatg agcccatggt tgtggtggag
    12721 ggctcatacc tgctgcaatt ccactaccct gccattgttg atgggaaaaa agcggtacag
    12781 gtggcttata atctagcact tgcaacggct aaggttatct gtacctacca agaacaagca
    12841 gcagagctga gcaatggcag tgttggtacc attctcaatc tgacaccgat ctatccggca
    12901 actgattcag aggctgatct tgctgctgct catgttgcag agctgtggca caatgacctc
    12961 tttatgtctg ctgctgttta cggtagcttt ccaaaggagc tggtagcaat actacaaaga
    13021 gatggagtgc tctggcagtc cacaccagag gagctggatc ttatggctgc ttatacggtt
    13081 gattacgtgg gcattaattt ttaccgccct aagcgcgtga aggcgccaga ggttattcct
    13141 gtgattagcc cttcctggag tcctgagtgg tattatgatg cctatctgat gccgcagcgt
    13201 cgtatgaatg tggacaaggg ctgggagatt tatccagagg cggtctatga tattgctcta
    13261 aaaatgcgtg atcagtatag gaatatccct tggtttttat ctgaaaatgg ggttgggatt
    13321 tcaggagagg atcgttaccg agatgagagc ggacagattc aagacgacta tcgcattcag
    13381 tttttaaaag agcacctgac ctatcttcat aaggggattc aagcgggctc taattgcttt
    13441 ggctatcatg tttggacacc tattaattgc tggtcttggc taaatgccta taaaaaccgt
    13501 tatggtctgg tagaaaataa tcaccgcact cagcgtcggc gtgtgaaaaa atcagggtat
    13561 tggtttaagg aggtggcaga ggcaaatgga attagctaag aaaagaagaa aaacacaaaa
    13621 gccagcccaa tctcctttaa agctaggttt agagaagcta agagagattt tacaggagca
    13681 gctagtagct ttagcggttt tacctgctag ggtgatgggt tagcataagg gcttgctgat
    13741 gagctatgcc agtgatagcg attaaggaat gtaaaagagg atttcctaac atcataacta
    13801 tccgtctaac gggtgattta ttgtttcgta cctacggagc gaaacggact aaagtcacat
    13861 aactaaaagc atgtcatggc ttgctgtagt acgagtgatg acatgctttt tttagctttt
    13921 aacgggttag ggagtagggc aggtcctcag ccgaatagtg cttgagtggg ggaactagtc
    13981 ccagctgaaa gtcgagctga cagccctgaa tcagatcatc atgattgatg tagagcttgt
    14041 tgtagctagc ctgattgagc ttgacctctt tgacaaattg gtattgaggg acattgcccc
    14101 tacagctgat ttggatagta ttgccatttg gcagataaag ggttgcctga tctacagttg
    14161 gaataccaat caggtattgc ccagttcctg gtgtaacagg gtaaaggcca aggctgttta
    14221 acaggtacca cgcgctcata ctgccattgt cctcatctcc tgggtagcct gtatcggtaa
    14281 aggcatgact gagcagattt ttaaggatta gctgactgta ttgtggctga ccgatatagt
    14341 gatagagata ggggaggtga aagcttggct gatttgagat agcaatctga ccaaaatcct
    14401 gtgcggctag ctcactcatt tcgtggattt caaagccata gctgtgaacg tcaaacacag
    14461 gctcatgatt gcacagctcc tcaagtcttt tggcaatggc ggcgtttcct ccgatcagtc
    14521 gaatgtaacc tagaatatca tgataaaagg caaatccatt ttgataatag gagccctcgg
    14581 tgtagtcctg cccccagtgg atagggttaa agccacattg ccattgccct tgtcgatcct
    14641 tgcttttgag gtagccggta tcagtatcga ccaaatggcg gtaattgagt gatcgcgtgt
    14701 ggtattggtc actaagtgct gtcttgccca gaagggcagc tacctggccg atacaaaaat
    14761 cactataagc ataatcttga gtctgattga cgctttcctg gtagctattt ggcagatagc
    14821 ctagctcttg atagtcttga ttgcccttgc ggccatagcc tgttccttga ctgtctgtat
    14881 tggcagttgc cagcatagcc tctaaaagct caggcatcag gtcttttctg atgcctttga
    14941 cagctccatc agcaataaca gcatcaacca aggttccagg catcaggcct cgctcatctg
    15001 gagacagcca ttttggcaga tagttggtgt cctgataagc tgacaagagt ccctctaaaa
    15061 tatcagcata aatctcaggt gcaattagag acagcaaagg atagacagat ttataagtat
    15121 cccaaaagcc attgttggta tagtattttc cagcaacagg tctttgactt gttgtattat
    15181 agtgaatcgc ctgcccggtt gcagtgattt cataccatct ttggggaaat agcagggctc
    15241 ggtaaaaatg ctggtagtag gccttgacct tatcaaagtc tttatcctta atgtcaatac
    15301 gactgaggta gctgagccac tccttgcggc tgtattcaag gcttttttca aatgatctgg
    15361 ggaaatccct ctgccaattg agctgagctt gatcaaagct aataaaagaa gcagccgccc
    15421 taagctcaag atgtttgagg tcatcagcaa attggagata ggtaaaggac gtcttgctgc
    15481 aatcatcaag agatttggag tttaagtctt ctccgataag cttttttagc acagggctgc
    15541 taaactgaag ataaacaaac atggctaggt ctttatcctg acagtctgtg atgttttgca
    15601 cacagccaag gattgtttta ccatcagctg tcacctgcca ggagcttttt ccggggttat
    15661 ggataatcaa gcctgctttg ccattatcaa aggaaaaatc acaatgaaag ctgtaggcag
    15721 ctgctgttgc tcgcgtcaaa atccgatgtc tctggctaaa aatctcaaga agatgaggcc
    15781 gaaaagctgc ctccttggga cgataggagg tctgattatg aaacacatct cccttggtca
    15841 gcggtccgct gactggaaga aaagtaaccg tcgcaaaatc accgacccaa gggctgggtt
    15901 gatgtgtcaa gcgaatacct gaaaagctgt gatcatcggg gtgaaaccac caagcccctc
    15961 gatcttgact ggtttcgacg cttagataat gcatgccaaa gggaacccct gtcaatggca
    16021 ggcaatttcc ctgtgaaaaa tggtagtgat tggttgttcc aaagcgggtg tcaatgaagt
    16081 ctaatcgatc cacatctcgt cctttctatg ctcttgcata aaatcaatag aggcacctag
    16141 taggttggcc tcgtttttaa agtggcagat agcaagctgc ggtctcaaat cagaaatgct
    16201 gactatctga tagagcttat ccagttcagc ctcaagggca ggaagaagaa agtcagcctg
    16261 agagacaccg ccaccaatta ggatcatttc aggatcaaag gcatgctgga tattaaacac
    16321 ccccattgcc agactttgaa gaaagacctg tctttccttt agggccacag gatctccttg
    16381 atcagctagc tctaagacct ctttaccggt gtaactttta ccatcattta tgatctgact
    16441 atagcgcttg gccatattga ccacagtgcc taattcgctg aaggtttgat aacgctcatt
    16501 catgaccata aagccaaact cacctccaaa taaatgggca ccgtaatgaa tcctgccatt
    16561 aatcactagg ctacctccaa caccggtgcc aagtaccagc atggcaaggc tgctagtgcc
    16621 ttgtcctgca cctagagcag attcggcaag agcagcacag ttggcatcat tttcaatcga
    16681 aaccggcaga cctagtcgct cctcaaggca ttgctgaatg ggaaagccat gaatataagg
    16741 cagtgcactt gctccctcga tgatacctgt tgctttattg acagctccag gggagctaat
    16801 ggcaattcct gagagctttt ctgtgcggta gtaagccagt cgctcgtcaa gcatatggta
    16861 aaagtcctct aggctttggg gagttgggcg actgctttgc ttttttagcc tgcccttgtg
    16921 acaaatagca aatttgatgc tggtgccgcc tatgtcgata cataataagg tcattgtaat
    16981 tcctcctata acaggtatat taccaattag ctacccttag tatgacagat tttgaagtgc
    17041 ttgaaaagac tttctcggca ttcctatatt ttgtgctatg atacctataa tttgtgttat
    17101 caaacctata atttgttgct tgttctatgt gtaagcgctt gatatacttg aagcatcaat
    17161 tgaaaagcaa agggaggttg ggaagatgac gacaaagatc agcagcaaga aatccttttg
    17221 gaaaaatgtg atcaaatacc gcgctttgtt gctgatggta ttaccgggat ttgtctggtt
    17281 catctttttc ttttacattc cagtattagc taatgtagtg gcttttaagg attttcatta
    17341 ctcagcagga ggttttatgg aaagcctgaa agaaagtccc tgggttggct tagataactt
    17401 taaatacctt tttgcctcta aggatgcttg gttgattacg cgaaatacca ttgcttataa
    17461 tcttattttt ttactattta acgtcttttt tgccatcgct ttcgctatta tcatgagtga
    17521 gcttcgaaac aagaaggctg ttaaggtcta tcataccatg tccttactgc cttatttctt
    17581 atcatgggtt gtgattgagt attttgtttc tgccttttta aatacggata agggctttat
    17641 taatcagctg ctcattgata gcggcaatag cccaatcaaa tggtattcca atcccacctg
    17701 gtggcccttg attttacttt tcatgagtgt ttggaaagga cttggctaca acagtatcat
    17761 ttattacgca tcggttaagg gaatatcaga cacctactat gaggcggcta tggttgatgg
    17821 tgccagtaag tggcagcaaa ttagacatat caccattcca cagcttttgc cgatgatgtc
    17881 tatcctattg attattaata ttgggagtat cttcaaatct gactttggct tgttttatgt
    17941 gattcctaaa aattcaggtc ctctttacga tgttaccagt gttttagata cctatgtcta
    18001 caatgccctg acagctactg gtgatattag tatggcttct gcggccagtc tttatcaatc
    18061 tgtggtcgga acctgtatcc tgctcatcac caatgctttt gttcgtcgta tggatcccga
    18121 tgcagcctta ttttaggagg aggacatgga gaaaaagaaa actgttaaaa gggtcaacgt
    18181 cagaaccttt gacccaaaaa ccaatgctgt ctttaatgtg ttaatcgctc tttttgccat
    18241 ctcttgtatc attcctttta tctttgtgat gattatttcc ttcacagatg aaagctatct
    18301 gatcaatcat ggctatagct ttttcccagc tgcttggtcg acaaaggctt atcattatat
    18361 tttccaaggg gctatgtctc atcggatcat aagatcgttt gcggtgtctg tatttatcac
    18421 cgttttagga acctttatca ataccacaat gacctcaacc tatgcttatg ccatctcaag
    18481 accttatttt ccctacaggc gtttttttac catctatgcc ttgatcacca tgctttttgc
    18541 accgggtatg gtagccaatt atttggtggt gagtaacctg ctgcaattaa aggatacggt
    18601 ttgggccttg attttaccga tggctctggg accctttggc attttggtga tgaggacctt
    18661 ctttaaaaag accgttcctg atagtattat tgaatccgct cgtatggacg gcgcaggtga
    18721 attgatgatt tttatgaaaa tcgttttacc tttggcagtt cctgggattg caaccattag
    18781 cctgttctca gccttaacct attggaatga ttggttcaat gcgctgctct atgtgcaaag
    18841 cgagagcctt tacccgatgc aatacctctt gatgaagatt caaagcaata tacaggcact
    18901 agcccaaaat gctggcatga gcgcccagct atctgatagc ttagcctctt taccaaagga
    18961 atctgtccgc atggctattg ttgtcattgc aactttgccg atcgccctaa cctatccttt
    19021 ctttcaaaaa tactttgttg gaggactaac catcggcggg gttaaggaat aatcacccat
    19081 ttggaatagg tcatacagct gaccgttcca atgattctgt tatcaaaaaa agaaattatt
    19141 ttaggaggct tactgatgaa aaagtggcaa acaatcttat gtgtgacggg agctgtgctt
    19201 gcagctgcta gcttgacagc ctgtggaagc aaatcagctt ctaaggacgg tgaggtgaag
    19261 ctattgatgt atcaggtggg agataagcct gataactttg atgagctgat gacaattgca
    19321 aataaacgta ttaaggaaaa aacaggggca acccttgatt tgcaatacat tggctggggt
    19381 gattgggacg acaagatgag gatcattatt gcgtcaggtg aaaattacga cattgccttt
    19441 gccaacaatt atgtggtcaa tgctcaaaag ggtgcctttg ctgatttgac taagctaatg
    19501 ccaaaatacg ccaagaaaac ctataagaac ctagatccgg cctacattaa aggaaatacc
    19561 attgacggta agctttatgc ctttccagta gatgctaacg tctatgctca gcaaatgctg
    19621 tctttcaaca aagaattggt agacaaatat ggccttgaca tttcaaacat caattcctat
    19681 gcagatgctg aaaaggtctt gaaacaattc cacgaaaaag aacctaatac tgctgccttt
    19741 gcgattggtc aagtctttag catgtcaggt gactacgatt acccattgac caaaaatcaa
    19801 ccatttgctg ttaaaatcga tgaaggcaaa ccaaccatca ttaatcagta cgaagatgag
    19861 ccctttaaag caaacctacg cttgatgcat aaatggtata aggaaggctt gattccaaca
    19921 gatgcagcaa ccaacacaga aggctacccg cttgaaggca atacctggtt catgcgtgaa
    19981 gaaacccaag gtcctatgga ctatggcgat accatcttga ccaatgctgc tggtaaagac
    20041 attgtgtcac gaccattgac aaagcctctt aaaacgacct cacaagccca aatggctaac
    20101 tttgtcgtgt caaatgtgtc taaaaataaa gaaaaggccg ttgaagttct ttcccttctt
    20161 aacagcgacc cagaattgct aaatggtctt gtttatggtg ttgaaggcaa ggcctgggaa
    20221 aaggttggcg acaagaaaat caagctgctt gatggctacc aacccaaaat gcacatgggt
    20281 gcttggaaca ctggtaacaa caagatcctc tacacccaag aatcgatcac agatgatatg
    20341 attgcaaagc gtgaccaatc aatcaaagac gctaaagagt ctccgatcct aggctttacg
    20401 gtagatacca aggcaatcaa aacggagcta tcaaaaatct caaacgtgat gaaccgttat
    20461 aaagctagta tcaatactgg tacagtagac cctgatgaag ctcttccaaa acttctttca
    20521 gaccttaagg acgctggttg ggacaaggtt caaaaggaag tgcaaaagca attggacgac
    20581 tttgttacaa aaaataaata aggcaatgga ctttccttgc aaggtggtaa gaactgggga
    20641 cagcctcagt tctttttagc tcaagcaggc atacaagagc tgacagataa ggcctctctt
    20701 agaaaaaagc cagagcctgc ttgcaaggca gttggtccac caaagccctt gctgacaagg
    20761 ttttaccagc cttagtcggc tgtcctcttt ttattaagct tttgtcacaa ttagagtaaa
    20821 atatgctata ttagaagtat ctcatcttat catcatgaca gctaagacct tagtcatctg
    20881 gctgagggat cgttgcttct cttagggcgc tattggtcct acaaaggata ctagaaaagg
    20941 ataatcttat gacaggaatt gaaaaagcct gctttctcat ctggaaaatg atgcagctaa
    21001 cccttatatt tcatttgctt tccttatgtg gtgctgtgat ttttggagtg gggccagctt
    21061 ggcagaccat tgttaccttg tttttggaga ccagtcagca ggagaaacat tattcgctca
    21121 agcgggcctt tcagatatgg cgtcgggtct tcaaagaggc caatctcagc tttttcttct
    21181 ttggattatt gctattattg ctgaatacga gcctgtactt ggccattcaa tttcaatcgc
    21241 tgctgtggtt tagcctatcc tttattatca tgtttgtcat ggtttggctg gtgatgattg
    21301 tgatttacat gaccttttat gcagtgacct atgaaattgc tttttgggag aatctcaagc
    21361 tgtcttttat cagtattttc ttgaatgcca ggcagttttt gttgaccctt gtggttttag
    21421 ctggagttgc ttggtttact tggcagtata agggcttgta tctttttctg agctttggtg
    21481 cgctggtttt gttgctggat atggtcacca agcctaatcg tcgcatggta gatggagtca
    21541 ttgatgacaa gtaaatcttt aaagcggttc ttgatggagc atattaagca gggcttttta
    21601 attaaccgct tgatgaaaat atatagcctg tttatcgtgg ctctctttag cttaagtgcg
    21661 gttggtctaa gcacctattc gattcgaaat acctaccaaa tggttgacaa tcaaatgcaa
    21721 atgcggctag atgagaccct agcaaggcta caatctcaaa actatattac cctgcgcgtg
    21781 ctggagcagc tgatcgggcg tccagaggat tatcgaaatc tgtatcagta catgatattg
    21841 acccctaatc aatatcttac taaggttttt gaggattggg gtgagggcaa aaacacacct
    21901 ctgttttcag agcaggtcag aaggcttttt gatttgtatc cagatttaga tgggctgacc
    21961 ctgatgctgg acgatagcac gtcctatttg tatgcagata ggtcgattaa gaccggccgg
    22021 ctcttatttg gtaagcctca gacgctaaag ggcaattact tagtaaggtc cattcgccac
    22081 cctgagtcag gtgatgttac aggccgcctc tatctgcact ttgcaagccc cagcacgatg
    22141 ctacagcctg agcagcataa gtatctagcg acctttgcct ttgattacta tggcagagag
    22201 ctctttcatc agggaggcgc tgcctttccg gagcttgaag caggtcttaa aaaggcgcta
    22261 aaggcggatc aggctattga tttgacagct ctcagcaaga gctatcatat tcagtacaat
    22321 cgctcgggag acttgctggc ctatgtggcg gtcaaaaggt cttattttat ggaagaggct
    22381 gtgcgtacaa tgctcctgta tggccttggc tcgttattgc tagcttggtt attgctacag
    22441 ctccttttca gggtatttcg caattatatc cgacaggtct ctgagattac agatactatt
    22501 gaaatggttg cagctggtga tttgtcgtta aggattgaca acagtcatat ggaattagag
    22561 ctgtatcaca tttctgaggc gatcaatcaa atgcttggca acatcaatgc ctacatttta
    22621 gaaatctatg tccttgaggt tgagcaaaga gatgcccaga tgcgtgcctt gtcatcacaa
    22681 atcaatcctc attttttgta taacacccta gaatatattc gcatgtatgc gcttagctgt
    22741 cagcaggagg aattggcaga tgtgatttat gcctttgccg ctttacttcg aaataacatc
    22801 agccaggata aggtaaccac tctaaaagaa gagctggctt tttgtgaaaa gtacatctat
    22861 ctgtatcaaa tgcgctatcc agatagcttt gcctaccatg tcaagcttga tcctgtcgtg
    22921 gctgatgtgg aaattcctaa gtttatcatt cagcccttgg tggaaaatta ttttgtgcat
    22981 gggattgatt acagccgcta tgataacgcc cttagcatca aggcgctaga tgaggaggac
    23041 agtattttga ttcaggtgct tgataatggc aagggtatta gccctgagcg cttagtggct
    23101 attgaaaagg gcttagagga gccgcaatcg acggggaata gctctattgg gctgcaaaat
    23161 gtctatatgc gcctatttca caaatatcga gacagagtga cttggtccat gtctcaggca
    23221 ccgactggtg gctttaggat tcagatcaga attagaaagg aagcttaatg tacaaggtct
    23281 tattagttga tgacgaatac atgattttac agggcctaaa ggtgattatt gactggcagg
    23341 cgcttggctt tgaggttgtg gcaacggcaa ggtcagccaa agaagcctta gcttacctag
    23401 atgactgcgc tgtagatgtc atgatttcag atgtcaatat gcctggtatg acaggcctgg
    23461 aattgattga ggcagcaaga gatgtattgc cgcatttgca gaccttgatt ttatcaggct
    23521 atcaggaatt ttcctatgtg caaagggcta tggagctaga gactaagggc tacctcctaa
    23581 agccagttga taaaaaagag ctggtagcta aaatgctcta ttttaaggaa tggcttgatg
    23641 agcagagggc agcttctttg cgtcaggctg cttatcgtga gggcttgata aatctctggc
    23701 ttgctgatga attgagtgag aaagagtttt ttcaactaac gcaggagcaa cccgaggctg
    23761 agcttttagg ctttacggtg ttgtatgtgg attgcaagac ttttagccct gccttagaag
    23821 ccttttttga ggcctccaag cagccctttt acttaaaaaa ggcagagcaa aagaaggtct
    23881 atctagtcat tctattagga cagagccatc aggctaagcg ctttactaat acgcttcagg
    23941 agcgatttta caataccatc aatcagatca ttctaggaga aacggttgtt gattgggaaa
    24001 atgtgtatga aagctataat caggtcagaa ggagcttttt ttacaacagc gaggtgtctc
    24061 aggtagctgc taagaccaac gctaaaattg agctgccgga atcgcgattg cagttttttt
    24121 cctttaacaa gaccttgatg attggggacg agccaactat tgtctccaaa ttacaggcaa
    24181 tctttgagga gatgacagag ctaagcttct ctcctgagga cgtcaagcac gtctcttttc
    24241 tcttattttc agacatttat cgccaatttc cgattttaga tcgaacgacc tacctatcga
    24301 tggtcaagac tattcacgat agtcagtcca ttgatcagat cttatcagcc ttaaaaaagg
    24361 tgcttgagct gacaagcaaa agcaatcagc cccaaaagcg ctattctgat ctggtcagtg
    24421 aagccattac ctgtattcag gaggaatact ctcaggaatt aaccctcaag gctgtgtcag
    24481 atcgcttgca tatcaatggg gtttatttgg gacaacgctt taaaaatgaa acagagtgta
    24541 gtttttccca atacctcaat caggtgagga tccaaaaggc acagcaattg ctgctttaca
    24601 ccaataaatc gattaacgaa attgcctatg agacaggcta taatactaac cattatttca
    24661 taaaaatgtt caaaaaatta aatggtttat cgcccaagga gtttagagac cgttataaag
    24721 ataattatca agctataaaa ggaagctatt aagaaagggg gcgctatgtc tgtagagaca
    24781 atcactggtt caacggatca atctcatggg gatatctatc agcttcactg gattgataaa
    24841 gtagggcgct gccatgcctt ttcaaagggg tggcgctttc tgatggctga tttgcagctc
    24901 gctcaggagc cattttttga tgattcggac tggcagcaga tagctttacc acatgatttt
    24961 agcattaatc agccctatac ggttaatggc gaagctcaaa gtgcctataa gctaggtggt
    25021 gtaggctggt accggaagta ttttgccctt gatccaaagc tggctgacca taaggtctat
    25081 gtgacctttg atggggctta tatggaaacg caggtatacc ttaatgggca tttgatagga
    25141 gagcatgtca atggctatca ggcctttagc tatgatctct cagcctttgt aatccctggg
    25201 caagagaatc tattagcggt tcgggttgaa catctggtgc ctagctcgcg ttggtattct
    25261 ggaagtgggc tttatcggga ggcttttttg accgttcttc cgaaggttca tcttgataag
    25321 gatcggcttc gtttatcctt atcccaggca gcgcttgagg ctgatagcca agcgcttgag
    25381 atagagcttg gactcagcca acaggtcccc ttgagtggct atcagcttag ccttagtctg
    25441 tttgagcagc tggcagatat ccagcagaga cagacagtat atgagagtaa accggtagcc
    25501 ttggacctct tggaggagtc aggtaggctg gtgatgacca ttcctcttag gcatatcaaa
    25561 ctgtggtcgc cagctcagcc ccagctctat cagcttgata tgcttcttta ccataaggga
    25621 gcagtgcttg atcggctgac acttgaaaca ggctttcgac agctgcattt tgatgctgag
    25681 tgtggtttct ttttgaatgg caaagccttt aagctgcaag gggtctgtct tcatcatgat
    25741 cagggtagcc tgggggcatg tgcttatgag gaagctatag ctaggcagct tgttttgcta
    25801 aaggaaatgg gagcaaatac ggttcgtgtc acgcacaacc ctagtgccag aaggcttaag
    25861 gatctggcta acaggcttgg gttatttctc attgaggaag cctttgatac ctggacttat
    25921 gctaaaaacg gtaatagcca tgatttttca agccattttc acaagacagt gggacaccaa
    25981 aatgcagcca ggctaaaggg agtcactaca gcagaaacca cctgggcgca atatagcata
    26041 caggccatgg ttctctcagg tcttcatgat ccatctgtct tgatgtggtc aatcggcaat
    26101 gaattgttag aaggcttctc agctgatgtg agccactacc cttatgttgc taaggagcta
    26161 tgccagtgga tcactgagct ggatcagtca agacctatta cccttgggga taataagctc
    26221 aaggacaagc attttcattg ggcgcaggaa acaaaagcgt tggcagagca ggtcaatcag
    26281 ctccagtccg tgcaaggagt gattggactt aactatgcta aggccagaga ttatgatcga
    26341 ttgcataggg acaacccgac ttggctgctt tatggctcag agacagcctc tgctattaat
    26401 agtagagggg tctatcatct caagggagga gctagtcagg atcatgagct aacctcctat
    26461 gaccagtcaa cggttgactg gggatcctta gctagtgagg cttggtatga tacaatcaca
    26521 agggattttg ttgcaggtga gtgtgtttgg acgggctttg attatctagg ggagcctact
    26581 ccttggaaca agattgactc aggcgcagct gatcagtggc cgtcgcccaa gcaatcctac
    26641 tttggtattt tagatactgc tggatttgct aaggatagct attatttcta ccaaagccaa
    26701 tggtcaaaag acaaaacgac acttcatatc ctgcccagct ggcaggaaaa agaccttcag
    26761 ctagatgatc agggcatggt ggaggttgtg gtttatagta atgctgctag tgtgagaata
    26821 ctttttgatg atggtcatgg gggccagatt gattatggca tcaagaccct gacaaggcat
    26881 gaaacaccag caggccattg ctaccagcta tatgagggtg acgatgcagc agaattacct
    26941 catcaaaacc tttacctgac atggaagctt ccttatcgct caggcagctt gagagctatt
    27001 gcttatgacg acaagggaca ggtgctcaca cagaccagcg gtcgttcctg tgtgagcagc
    27061 taccagcagc ctgctcagct ttcctggtcc tgctttgagc ctcctaaact gcttgcagag
    27121 cctgcgctac tttatcttga attgtctttg ttagatgcta atgagacctt ggtgctcagt
    27181 gctaatcctg tgattaagct tgaggttgag ggtcctggag cctgccttgc tctggataat
    27241 ggcgatcctc gtgaccatag gccctatact gccttgtcac gccgagcata tggtggcaag
    27301 ctattagcca ttattgctct tgatggtcgt gcgggtcagc ttagaataac agctagagcc
    27361 gcaggattcg tggaagccag ctatcagttg acggtttctg aagcagccgt taatgagaag
    27421 cttttagcct atcagcttga taaatacagc tttatcacta atgagacaaa taagcctagc
    27481 aagccctatg caaggtcaag aggatcagct gttgatagct taatgcctaa tcctgatagc
    27541 tgcttaaagc ggcaaggcca ttatctgcct gataattctg taatggtttt tagctataca
    27601 acagcattat caaggccact gacctttcag ccactgatca aaaggctgct aaagggcaat
    27661 gatatcattc taccagactg gctgcagcct agggcagctg ctggccagtt atttaccaag
    27721 gcttttccta ttgattggca gctaacagag gcagtttttt ctgaggagtc aagggttagt
    27781 gggcagaccc tttgttttgg agaggctttg gagcttgaag ctatccttaa gtcagataca
    27841 aaaggattaa ggatcaatca agagcttagc ttagttgcta aaaagaagcg gctgtttcag
    27901 agtgataccc agcttagcta ccgctatcaa tacgatacca tacaggccat tggtgccatt
    27961 agcctgacag gactaaagaa gcccttaagc tcgcttaggc ttgttttgga ctatcgcagc
    28021 agcaccaatg cgccatcaaa acagctgatc ctatcgcttg atcagataga acagccctgt
    28081 cactacatca tgctggaaga agtagttgat gtgctaagcc tggacctaac attagagcag
    28141 ccgatcagac aggcttttga cttagctagg cttcagctag gcctttggag catggttgag
    28201 gaggcttagg cttcaagctt atcggctcat actgtcaata ggattgagct gagacagtct
    28261 ttgaaaaata aggtataatg acagtaaatg cctagcaagc tttgctaggt tagcaaaaaa
    28321 taagcatcgc ctgatatgat gtaaaggagg aggtatttga tgctagagcg tttatcaggt
    28381 cagacacgat taacagcttt gctggcagca ccggcacgtc acagcctatc accgaaaatg
    28441 cacaatgcag cttatgctaa gctggggctg gattatgcct acctagcctt tgaggttggt
    28501 aatgctgagc tagctgctgc tgttcagggc atgcgtgcct tgggtatttg cggtgcaaat
    28561 gtgtccatgc caaataagca ggccattgtc ccattgcttg atgagctatc accggctgca
    28621 gccttagctg gagctgttaa tacggttgtt aataaagatg gcagaggtca tcttgttggt
    28681 catatcaccg atggcacagg tgctattcga gccttagcag aagaaggggt ctcgataaag
    28741 gatcagatca ttacgattgc cggtgcaggc ggtgcaggca cagccattgc tgttcaactg
    28801 ggacttgatg gcgccaagga gattcgacta tttaatcgga aaacagctac ctttaagcag
    28861 gccaagcagc tggttgctag aattaatacc caaacctcag ccctggcaag ccttcaggat
    28921 ttagcggatg atcgagcctt taggcggtct atttcagagt ctagcattta tattgacgcg
    28981 actggtgtag gcatgaagcc ttttgaggag catcgcctga ttactgatcc agctcttatt
    29041 cgcccagatc ttgtggtttt tgaccttgtt tatcacccgg cagaaacaaa gctcttagcc
    29101 tttgcgcgtg agcatggggc taaaaaagtg atgaatggcc taggcatgct cctttaccaa
    29161 ggagcagaag cctttaagct gatgacaggt gaagacatgc cggtagccta tatccgagag
    29221 cttttatgtc agaacaagga atgaacgcct gctgctcacg ccggtatagg aaaaagaaaa
    29281 aaaggttaat tgctcagctc tttgattggt cttgaggttt gtcggcattt tatttataat
    29341 aaaaagcacc aaaagcaaag gagcagccta tgatattgac acaatttgac cctgactacc
    29401 aagctatcat taaccctaag gaccttgtag cagaaataga tgactttcct aaaacagtag
    29461 tcacctgctt tgcaagagca acctttaata gggtacttaa tgcactgcca catcgactga
    29521 tagccacaac aagcgttgct aatcttgata ttccaatata cgaattagat gttaaagggc
    29581 ataagcttgg ctttttcaat tcctacgttg gagcagctgg ctgcgttggg gttttagagg
    29641 atatcattgc tatgggaatg aagcagctct tggtttttgg gacctgtgga gtcttagacg
    29701 ctactatcag tgaaaactct attattattc caactagtgc tattcgagac gaagggacca
    29761 gctaccacta tcagcctgct agtcatgaca ttgcagtgaa tcaagcttat ttaacaaggg
    29821 ctattgatgt tttagaacag cattcccaga cctataccct tggtaagacc tggacaacag
    29881 atggcattta tagagaaacc agagacaaga tgattcaacg aaagcaggaa ggggctattt
    29941 gtgttgacat ggaatgctct gcgattgctg ccctagcagc tttcagacag ctagagcatt
    30001 ttcagttttt ttattccgct gataatctag atgctgatga atgggacgca agaagcttag
    30061 ccaatgaagc agacctagaa gccaaggata acattgcctt tattgcctta gagttggcct
    30121 tacgattatt taaggataat taaaaaagca ccaagagcta tgaagtgcct ccaaaaggtt
    30181 agattaaggc tctaacgcct gggagatcag ttcagctcaa ggtgcttttt aggtgtcatg
    30241 cagacagctc acctctgcat gtcaatataa tgtttagagt agcctatgct tcttatacct
    30301 atgccttagc attcacctag ggacaaagca atgaagctta ggcctttcac cttactgtga
    30361 aaaaagtggt cttttctcat caaaagactc agtaaacaag aggctttgaa gcctttttgt
    30421 ttttcagaag cagcagtttt ttcactcgac taataagaca ggagaaaagc cttctcaggc
    30481 gatatctagc aggcttctta gccaatccag caggcgactg tcatgcttag caataggaaa
    30541 gcttacatag ccttttgtcg ttggcaaaat gaggacaata tgctgaccag aatttttctt
    30601 atctgttttt aaaacagtca tcaaggcttc ggctgtcatt gacttagcct caagtgtggt
    30661 aggtagctga taagcctcaa aggcagcctg taatgcctct aaatcctgtt ggctcaatag
    30721 ctgctgctgg acggccagct tggcctcaaa gaccatgcca atcgcaatag cctcaccatg
    30781 cctgtaaagc tcgtgatggc ataaggcttc aatcgcatgc cctagcgtat gcccgaaatt
    30841 taaggacatg cggagattgc cttcaaattc atccttttca accactcttt ttttatggca
    30901 aatcgcttga aaaatcattt gcctgagctg ctcttgattg cggtccttgg ggaaggctag
    30961 gagctgttga aagagcttgc gatcatgaat aaaaccaatt ttaatcattt cgctgatgcc
    31021 gcaggcaaat tctctttcag aaagcgtgtc taaaaacttg gctgacacga taatctggtt
    31081 tggagggtag atactgccta tcatattggt caagccctta aagtgaaccc caaccttacc
    31141 accaatgctg ctgtctacct gactaagtaa ggttgttgga atctgaacgt aggaaatccc
    31201 gcggtaaaag gttgccgcaa caaatccccc aagatctcca atcacccctc ctccaacagt
    31261 aacaatgacg tcctttttag aaaaattagc cctaatcagt cgatcgtaaa tccgactaac
    31321 ctcctctaga gacttagatt gcccccctgg agcagcaata tgaaggtaac tatcgtaatc
    31381 ctgttgaaaa cgtctaaata aaggctggta taaatcaaat accgtttgat cagtgataaa
    31441 taatagcttg acgtctcctt tttcagcaag aaattgattc agcggctgaa aaatatcgtc
    31501 tgtaaagata atcggatagt cattgatacg agacttaacc tgaagtgttt gtgtcatgcg
    31561 tctttctctc ctaagcacca ttagttcaaa tgactggacc tgtggctgct gttagttagc
    31621 tttcccaaag ctcttttcca agctgctcta gctgttgata atcaatctgc tgcgcggcat
    31681 ctgacaaggc aagatcaggt gtagggtgca cctccatcat aataccattg gcaccgatag
    31741 ccttagcggc cttagccgca ggcaatagta aatctcttct tcctgttgag tgagagacat
    31801 caacaatgat tggcagcttc accttttgct gaataatagg gactgccatg atgtctagca
    31861 tatttctagt ttccacatca tagccacgaa ccccacgctc gcataaaata atattttgct
    31921 tgccattttc ttgtaaataa gataaagcac ccaaatattc ctcaatggtt gccattagtc
    31981 ctcgtttaaa caagataggc ttgtcaatct ttgacaatac ctttaacagt tcaaaatttt
    32041 gcatatttcg agcgccaatc tgaataatat ctaaatagtc ataggcttcc tctagctgcc
    32101 tttcagacat aatctcacta acagccttca gcgaaaattc ctggcaaacc tcatgtagat
    32161 aggtaacccc tgtcagccct aagccctgaa aggagttaga agaggttcta ggcttatagg
    32221 ctccccctcg aaaatacctg tagcctaaag ccttggcact tgctgctgcc tgtctgattt
    32281 gctgataaga ttcaatggca cagggaccaa caataaagtt actcttttga cagcccttgt
    32341 ttaaaaaatc agctattata tcgtttccca tttatactct ttcctaatat gatattgaga
    32401 gaatgattcc ccaaaggtaa gatgacagct ctgtcttaga taatactgtg aataaggcat
    32461 gacagaacta ttcatagctt gggaaatcat accataatca agcttaaatt tcaagctaat
    32521 aaagagagtg accagctcgt tgacaaagga gaagcttttg agaatcctag ccctctaagg
    32581 tagagatttt atggctatta gagctgttga gaatgcttat tagctggaat aggcaagcat
    32641 ggtggggaag tgctgatgat tgagtatcat gatgaggcta gttatagctt ttattgtggg
    32701 agagtttagc ttttcaaata caaaaagaaa aggtttacct atatcgtttt tttggtgtat
    32761 atataatata tagaaagcaa actattttag aaacagaggt aatggtagat gttaaggtat
    32821 ttaaaagcga ttttatatct attggctccc agattagctt tttcagtaac aggtgtatta
    32881 tttcctgatg tttttgataa tttattcttg gtttataata ttttaatgac acttgctttt
    32941 tggcttgcga tttattctgt tgacctccca gaaaaatagt tgcgggactt gtttagtagt
    33001 tggttaacaa agggtagatg atcagttaaa ggtgaagcgt ctgagctatg ttggccatta
    33061 tgcgtacagc tggcaaaatg cttttgatcc aatcggttaa acctcaagct attctctttg
    33121 ggataacaaa taccccatct gtctcagaca aagaatggca acgcctaaat aggattaaca
    33181 tctgcaagtg ctcttgggac tgccaatgct cttagtagca taggtgattt ttcagcgcta
    33241 gagacttttc agcagatgag aaatagtcgc aataaacgaa gacaaaaaga cttggcttga
    33301 gctcgtattt ggccttaaaa tagtagtcag tcgagcttaa aaaaaagtca ttgcagctta
    33361 tgaaggttat cgtatcctta tttcaactga gctaggtaag ctagggagtt tcctttaggt
    33421 gtaacgatag aagcgatcaa ataattactt catttaaaga taaggattgt aataagcata
    33481 gaaaagagca gttacttgac ataactactc aatgtaaaac cgtttcaggc ggtggctttt
    33541 gttattagat aaaaaataat cgtcatcatt cggccaaagt tagaacggtt atgttttatg
    33601 ctcatctttg aagatgttat agcacaagcc aatagggaga ctaaagctta aaaagagttt
    33661 gagtagcttc aaaggctgct agctttttgg cctcctccat tttgttagct gttgatgaat
    33721 cgcccatagg caccaccacc cactcagaac gagcagccac ctgtcttaat ttttttactc
    33781 taccactgta gcatgccaca agaaaaaatc agaacactaa tgacatttta aaaaaaaaaa
    33841 aaaagacttg cacaccaaaa caagttatag tatcatagaa aggtagccgc tatagttaaa
    33901 tggtataata aagcaatggt aatgcttcgt tccgagttcg attctcggtg gtggcatctg
    33961 agtactgtcc taagtcttat taggacggtt tttttattgc taggtgaacc aatagtagtc
    34021 atctgtgaat cattaccata gtggcttctg ttcgcccaag catagcaaag ctgctgtcag
    34081 aatgaaccca gccaacaatg tcaatagaag cagcaccaga caagccttta gtcacccatg
    34141 ctttaaagat tttacggctg taatgttagt aactgttacc tgttttgttc aagttgtctg
    34201 tgacatcaaa tcacttgatg ctaccagtac tgtcaataca ttagctgtca cttggcagtt
    34261 gttctgacta ctactaaaaa tagcagctat cagcgttgca atcaaaaaag aatgcgaatc
    34321 aagctctcct gatcagctta actttttgaa agagtttgta cgggtcaagc atcagcaagt
    34381 cagactgcct tatttgtttt tatcataagc ttctaagaaa atagcacaat aagccaggct
    34441 gtggtataat ggtaaggatt aagtcagaaa gaggggggca gacatgtctt atgagcaaga
    34501 ctttttgaga gattttgaag actgggtgaa ggctcaaatt caggtcaacc agctagctat
    34561 ggcaacgagc cggcaaattg caaaggaaga taatgatcaa agagccagag atgcctttat
    34621 tcgttatgag agtaagctag atgcttatga gtttttatta ggaaaatttg ataattataa
    34681 taaaggtaaa gcttttcatg aggtgccaga cagcctattt ggtagccgtc attattagag
    34741 gaagggataa gcagtaatca tggcaagacg atacaatcgt aaaaaacaat acaagctaca
    34801 gcttaagcgt caaggactgc tcaaggcagt aatcaatcaa gtggagcaga ctgtggaaaa
    34861 ggtggttgat aagactaaag aagcagtgca taccgcttca caaatggtaa cagcatcaaa
    34921 gacagagact gctgatctac aggataagca gagcattgct gaaaaagcag ctcagcctaa
    34981 agcagatgta gcttctagta gcttggctga cagttctgag gtttcaagtg aaaaagaggc
    35041 ctcaaaggct agcagtgaag tcttatcacg cgatgctttt gcagagttgg ctgaggtttc
    35101 agagcttcgg gcagatattg ttacggtgct ttttgaggct ggtattaggt cagctgctgc
    35161 ttttagccaa tggacagagg cagagctttt ggcgcttaag ggaattggac cagcgactat
    35221 cagcaagcta aaggaaaatg gtgtcaactt taaaaagtag tctgattttt attgcttaat
    35281 aagtataaat ttgttagaat gttagcaatc agaggtatct tgagtttgtc tgttacagag
    35341 agcggtggtg ttgagaaatc cgcacagatg tcaagttatg tagctgaggc ttacaatgga
    35401 aaaatgataa agcagcagat taagtgtaat ctgaaacagt ggtggtaccg cggattatta
    35461 gtgaattcgt ccctgtctag tcgattgact aggcggggtt attttttgga ggacttgcta
    35521 tgattgagat aatgggttct gttgagaata atagattacc agatgtcaaa actagtcgtt
    35581 tgctgctgcg gcagcgtact ttagctgatg ttgaagcgat ttttgcttat gctagccgac
    35641 ctgaggttag ttacccagca ggctttccac ctgtgaaaac ccttgaagaa gaggagcatt
    35701 acatcgcaaa cacgatgcct aagcgctggc ttttgcaaca gctgccggca ggctatggca
    35761 ttgccctaaa gggtgacaat aggattattg ggtctgttga ttttaacaac cgtcacgcag
    35821 atgatgtctt tgaaatgggc tatctgctcc accctgatta ttggcatcag gggattatga
    35881 ctgaggcagc gagtgccctg ctagaggttg cctttactct gcttaagctt cataaggttg
    35941 aaatcagctg ttacgattac aatatgggga gtcgtcggat cgcagaaaag ctagacttca
    36001 ctcttgaggc gaccattcgt gatcgcaagg acgctaaagg caatcgctgc gcagacttgc
    36061 gctatggact gttgaaaaga gaatgggaga ggcagtgtag ataaggagta gactctctaa
    36121 aatatgcgtt aatctgtcaa aagcatttca taagaagtcc tcaaactcaa agcgcttatg
    36181 actaccaaaa ctggttagcg cttcgccaac cagtgtcatc agtttctggt agtctgcctt
    36241 gagcagcaag tgttatgtta agtgaggtga gaagaggtaa gagagatcgg aaagaggttt
    36301 ggtatgaata ttatcttaat tggagcacag gcgtctggta agatgacaat tggacaggaa
    36361 ttagaaaaac tgactgacct gactttattt cataatcatg aatcgattga ttttgtgact
    36421 aagtttatac caatgtcatc ggaagctaga gaactaattg atgagctacg attgctattt
    36481 tttaaaacat ttgcaaaacg tcagcaatca attattttta ctgttgtcat tgattttaat
    36541 gcacctgaag atatagcgtt tttggaaaca ctacagagtg tgtttcatga tttcgacaga
    36601 gaggttttat tcgttgaatt agaaatagat ttaaaagaac gcttaaggcg aaataaaact
    36661 gaaaatcgac tttaccacaa accgataaag cgtcatttgg agtggtctga gaaagatatt
    36721 ttggatactg ctaaatttgc taactttaac cctgcaaagg taccagaaaa tcttaaatat
    36781 tattgtaaaa tcaataatac gagtctttct gctcaagaaa cagcgcagtt tatcgtccaa
    36841 aaaatgaaag agttagaagt aagctagaaa ggacaccata tgtcaaaaga actttcaccc
    36901 aaatacaatc cagctgaggt tgaggctggg cgttatcaag cttggctgga ccaagatgtt
    36961 ttcaagccat caggcgacaa gaaggctaag ccgtatgcta tcgtgattcc accgccaaac
    37021 gttacaggga agctgcacct tggtcatgct tgggacacga cccttcaaga tattattatt
    37081 cgtcaaaagc gcatgcaggg ctttgatact ctctggttgc ctggtatgga tcatgcaggt
    37141 atcgccactc aggctaaggt cgaggagcgc ttgcgcgagc aggggatttc ccgttacgat
    37201 ctcggtcgtg acaagttctt agacaaggtt tgggaatgga aggacgagta tgcagcaacc
    37261 atcaaggagc agtggggtaa gcttgggctt tcactagact atgcgcgaga tcgcttcact
    37321 cttgatgagg ggctctcaaa ggctgttcgc aaggtttttg ttgagcttta caagaaaggc
    37381 tggatttacc gcggtgagtt catcatcaac tgggactcgg cagctaggac agctctttca
    37441 gatatcgagg ttatccataa ggacgttgag ggtgccttct accacatgaa ctatatgcta
    37501 gaagatggtt cgcgcgccct tcaagtagca accacacgtc ctgaaaccat gtttggagat
    37561 gtggctgtcg ctgtcaatcc agaagatcct cgttacaagg acttgattgg tcaacatgtt
    37621 gttctgccaa tcgtgaataa gctgatccca atcgttggag acgagcatgc ggatccggca
    37681 ttcggaacag gggttgttaa aatcacacca gcccatgacc cgaacgactt tgaggttggt
    37741 gggcgtcata atctcccaca ggttaatgtc atgaatgatg atggtaccat gaatgagctt
    37801 gcaggtgaat ttgcaggtat ggatcgattt gaagctcgta aggctgttgt ggctaagcta
    37861 gaagaaatcg gtgcccttgt tgagattgaa aagcgtgttc attcagtagg tcattcagag
    37921 cgtacaggtg ttgtggttga gcctcgcttg tcaacacagt ggttcgtgaa gatggaccaa
    37981 ttggctaaaa atgctattgc caaccaagac acagatgaca aggttgactt ctacccacca
    38041 cgcttcaacg ataccttctt gcaatggatg gaaaatgtcc acgactgggt aatctctcgt
    38101 cagctttggt ggggacatca gatccctgca tggtacaacg aagcaggtga catgtatgtt
    38161 ggtgaggaag cgccagcagg tgatggctgg aagcaggacg aggatgtcct tgacacctgg
    38221 ttcagctctg cgctttggcc attttcaact atgggctggc ctgatgtaga ctcagaagat
    38281 ttccaacgtt acttcccaac gtcaacattg gtaacaggtt acgacatcat cttcttctgg
    38341 gtgtctcgta tgattttcca atcgcttgaa tttactgggc gtaagccttt ctctaacgtt
    38401 cttattcatg gtctgattcg tgacgaagag ggacgcaaga tgtctaagtc gcttggaaat
    38461 ggcattgatc caatggacgt tatcgaaaaa tatggtgcag atagcctacg ctggttccta
    38521 tcaaatggct cagcccctgg tcaggacgtg cgcttctcct atgaaaaaat ggatgcgtcc
    38581 tggaatttca ttaacaagat ttggaacatt tcacgttaca ttctcatgaa taatgagggc
    38641 ttgacacttg agcaagcaag tgcaaatgtt gagcaagttg cgtctggcgc tgctggaaac
    38701 gtgacagact gttggatcct ccacaatctc aatgaaacaa tcggtaaggt cacagagaac
    38761 tttgataagt ttgagttcgg tgtggcaggt catatcctct acaattttat ctgggaagaa
    38821 tttgccaact ggtatgtgga gctgaccaag gaggttctgt acagcgacaa cgaagacgag
    38881 aaggttatca ctcgctctgt tctcctctac acgctggata aaatcctgcg tctccttcac
    38941 ccaatcatgc cgtttgtgac ggaagaaatc tttggtcaat acgctgaagg ttctatcgtg
    39001 acagcggact atccaacggt tgatcctgct tttgaaaatg aagctgcgca caaaggcgtg
    39061 gaaagtttga aggacttgat tcgtacggtg cgaaatgcgc gtgcggaggt taatgtagca
    39121 ccaagtaaac caatcactat ccttgtcaaa acaagcgata gcgacctgga agccttcttc
    39181 aacagcaatg tcaactacat caaacgcttc acaaatccag agaggcttaa gattgcttca
    39241 agcattgtga ctcctgagtt ggccatgtcg gctgttatta caggtgcaga aatcttcctt
    39301 cccctagctg atctgctcaa tgtcacagaa gaattagctc gccttgaaaa agaattagct
    39361 aagtggcaaa aagagcttga cctggtcagt aaaaagctca gcaatgaacg cttcgttgct
    39421 aatgccaagc cagaagtcgt tcaaaaagaa cgcgacaaac aggctgatta ccaagctaaa
    39481 tacgatgcaa ccgtagagcg catcaaggaa atggagaagt tagtaaggta ggatagtgat
    39541 catctaagag ccaattggct ctttttttga tatactgtca aggagtaatc atcacaatta
    39601 tctatataag tcaaaggagt gtctcatgaa aaaaagagtc attggttggt taggtgtgct
    39661 ggtaataggg cttatgcttg gtctgatatg gtggaaatgg ttagtggcag atcggccact
    39721 aacccaagca ggtcaaggaa gtcatgacca cagcagcgac aaaggcctca gtgccgcata
    39781 aggaaaaaat ggaatcaaaa gagcctgaga catcacatca gccagaagcc tatcctgatc
    39841 ttgctagcta tcaggaattg gctgttcatg tgtcgattgc agaccaagtc atgaccatta
    39901 taggagatgg taaggttatt tttaagacca gcgtgtcaac aggagcaaag gaaagtccaa
    39961 caccgacagg gacctttgtc attgagcctg agcgaggaga ctttttcttc aatcaggcat
    40021 cagaagaggg agcttattat tgggtgtcct ttaaggacca tgggatttat ctgtttcaca
    40081 gcctaccaac agaccaatat ggcaatgaga ttccagagga ggcagagaga ctgggacagc
    40141 cagcctcaca tggctgtgtc cgcatgagca gagcagacgc caaatggttt tatgacaata
    40201 tcccagaagg catcagcgtc acaatagaat agccctaatc tccctcagaa tagcctgagc
    40261 agatagagga agagcctgtt aatattagca ggcttttaaa gctccttaaa aggctgcaaa
    40321 aaggaacgaa aaaagacctg aaacaggtcc attgatctaa gagaagacaa gtaactagcc
    40381 ttctagcaaa gtgttttaaa aatgcgttag tttagtagct tcgtgataat acaattaata
    40441 atatttattt aaaaaaactg taaatttcga ccactgttcc tggatttttt catttaaacg
    40501 tttatgccat gacttatgag cattctctct aatttctttt aggtatatat tttctactac
    40561 ccttttttga ctatgttctc gctctttttt tatttgctgt cttaaattct cttgtttttt
    40621 ctgttcttct aactcttttt gagctttctt ctgttcttgc tctattatgt cttgaggttt
    40681 agattctcct acaatccata tttctgaacc taagacaaaa ccatctgagg taatatgaac
    40741 tctaaattta tcaccattag aagcaatttt attatatgga acatatgttt cttctttgga
    40801 atttgttttt tgtgttctcg ctgattctaa agagaacaca atttttccat cccactttgc
    40861 aattggatag taccggttat ttgttaagtc accattgctt tttttttgga cttgtactaa
    40921 ttcagtttcc ttatcatctt cttcgacttt aaatattcta atcaaagatc ctggactagt
    40981 ttttactact atttctttgt cattattttt gattggttta acgccaaagt ctcgagcgtt
    41041 ttcccaatct cttctaaatc ctattacctt ttggtcacca atttgtggtg cttctgtata
    41101 atcatcataa ccataatagc cttgccctaa aactggagaa ttttcataat cactatttgc
    41161 acttacttcg ttgaaacata ttaaacttag taaaggtaaa ttaacgatta aactcatcac
    41221 taacttcttc ttcatttttt cttcctaacc tccattactt atgtttattt aataatagct
    41281 agggttagta taaatgagat gttgtgtaag gtaaagatgt ttattaaaag tgactaaaag
    41341 taaagaaata atcctaatag tagtttgggg atattttgat ttatacaaaa aataatgtca
    41401 ttgaacacgc tttatctaaa atagtctaac attctaacga aaataattcc aattattttc
    41461 atatactggc tagacatgct gtattagctt aatcaagaat tacagccgca gttttaaaga
    41521 cactcaggtt agtgtattat aaaaagctgg tgtgggttac aaaggatttc atatcactta
    41581 gattatgtca taattagtta agatgatgaa tccttatcta aaaacaaagc aaacttgtac
    41641 gtttgcgact ttcgtgatct ttaagcttac aaaagctgag taaattggta taatgatcat
    41701 taaaagagct catgctatga tgtagaccta taaaaggaga aaaccatgac atttgaagag
    41761 attttgccag gcttgaaggc caagaaaaaa tacgttcgta agggctgggg aggcgctgaa
    41821 aactatgttc agctgtttga tagcattgaa caaaatggtg tggcacttga ggtgacgcct
    41881 tactttttga ttaacgtgtc aggagctggc gagggctttt ccatgtgggc accgactccc
    41941 tgcgacgttc ttgctactga ctgggtagag gtctatgact aagcgggtgc tgatcactgg
    42001 tgtgtcatcg ggcataggac tggcacaggc gcgcctgttt ttgagaaatg gctttactgt
    42061 ttatggggtt gacaaggcaa aaaagcctga tttatcagga gattttcagt ttttacagtt
    42121 agatattaca ggtgatttag ctgagctttt tgaggctgtg cctagggttg atgtgttgtg
    42181 tcatactgcg ggcgttcttg atgcctataa gcccttgctt gataccacac aggctgattt
    42241 tgaggctctc tttcaggtca atttctttgc agctgtccgc atcacgcgtc actatttggc
    42301 acagatgctg acagctcaat caggtattat catcaatatg tgctctattg ctagcttcat
    42361 ggcaggtggc ggcggagctg cctatacctc cagcaagcat gctctggctg gttttaccag
    42421 acagctagcg cttgattatg ccaaggcagg cattcaggtt tttggcattg cccctggcgc
    42481 agtgcaaaca gcaatgacag ccacagactt tgagccaggt ggcttagccc agtgggtggc
    42541 tgatgagact cctatcggtc gttggcttag ggctgaagaa atagccgagc tgaccatgtt
    42601 tttggcatct ggaaaagcta gcgccatgca gggagaaatt gttaaaattg atggcggttg
    42661 gagcttaaag tgaaacagca catcgacata aggcctagca agatctggct tgtctgtaca
    42721 gagggtgaca gttgatagct gtatcaagca atcttgtcac aggctaagag ggagctgatg
    42781 aagttttttc catgaagcct agtgcctagt aggtttgctt aatacagcag gagcctacct
    42841 gtctagagga ttcgatcaat agaggtgata acatgactgc agaagaatta tggtctcaat
    42901 accagcaaat caatcctggt gttggtgatc tagctgaggc ctgggccttt ggagctgagc
    42961 ctgatttatt agcgcaatta gtgctagaag gcactaaaac agctacagcc tctgcctatg
    43021 actgatatga gcctgatcat gagccgcttt ccaaagaggg cagctatgac gtgattttgg
    43081 atagtaggga tcaggcgatc tgtattatcc agattactaa ggttagtctt gttcccttca
    43141 aggacgtgcc agcagagcat gcctataagg aaggagaggg tgataaaagc ttggaagaat
    43201 ggcggctgct tcatgaggcc tttttcagac cttattttga agaggtaggc ttacgcttta
    43261 ccgaggatag ccttattgtg ttagaggagt ttcagagggt ttaccctgaa gctgctaaaa
    43321 aggagaaata aatgaaatta gcccttgttg gtacaggcat gattgtcaaa gaggttttgc
    43381 ctgttttaaa ggagatcaaa agcatagact taatggcgat tgtttcaacg cctcgtagtc
    43441 ttgaaaccgc agaggcgctt gctgacgcct ttggcattca acaggccagc tgtcagctag
    43501 ccgaggtcct aaaaaatgaa gaggtggata cggtttatgt tgccacccca aatcatttgc
    43561 attttgaagt ggctaagcaa gcccttgagg ctggtaagca tgtcatttgt gaaaagccat
    43621 ttaccatgac agccaaggag cttgatgctt taagcagcat tgcaagagct aagcagctga
    43681 tattattaga agctattacc aaccaatatt tgccaaacac ccaatttatt aaggatcact
    43741 tgactgagtt aggagagatt aagcttgtgg agtgcaatta ttctcaatat tcctctcgtt
    43801 atgatgcctt taagcgtggg gagattgcac cagcctttga tcctaaaaag ggtggagggg
    43861 ccttgcgtga tttgaatatt tataatatcc atctgctcgt tggcttattt ggcaagcccc
    43921 aaacggttca gtacctagct aatatggagc ggcaggttga cacctctggt gttttgctga
    43981 tggattatga gcgatttaag gctgtttgta ttggggctaa ggattgcagt gcagagattg
    44041 tctctacgat tcaggggaat aaaggctttc tttctgtttt aggtgctcct aatgctgtac
    44101 cagagctttt actagccatt cgaggtgagc aagcaaggac cgtcaacttt aaccacccgt
    44161 ctcatcgcat gtacgatgaa tttattgcct tttcagatat tatctctaat aaggacatgg
    44221 aaagggcaga gcaggccttg gagcacagca aggcagtcat ggctgtttta gagcaggcag
    44281 cagcttcgct agaaagcgat agctaagagt agctagtggc tacaagctaa gtcatctttt
    44341 ttgctagctg tcttaagaag tgatgaccct tcttgttcta tcagatacag gtcttgttcc
    44401 tgatgactcg gagtctttca atcgcggagc ctaactgctt ttttcatagt gaggggtcta
    44461 atttgcagct tgctttgttt acgacatctt tgatacttag cgatgacagg cagctctagc
    44521 tagctgcttt aaaaaaggag tcaaggtagg taagggagtt tgtctgaagc taaggactat
    44581 tgcagcattc ttgttttttc tgcaaattaa ggccatttgt gctataatga gatgatctat
    44641 gtacaaacgg aggaagtcat tatgc
//
LOCUS       DARYNN010000013        43780 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.013, whole genome shotgun sequence.
ACCESSION   DARYNN010000013 DARYNN010000000
VERSION     DARYNN010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43780)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43780)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43780
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.013"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(19..1290)
                     /locus_tag="TVB59_000652"
     CDS             complement(19..1290)
                     /locus_tag="TVB59_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEL1009581.1"
                     /translation="MPDNLAIRMRPRTITEVIGQQHLVGEGKIIDRMVKANRLASMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATIDNKKRLQEIAEEAKFSGGLVLLLDEIHR
                     LDKSKQDFLLPLLEHGHIIMIGATTGNPFFSVTPAIRSRVQIFELEPLSPEEIKQALK
                     LAITDKERGFAFDVTLDEAAFDFIATATNGDLRAAYQSLDLAVMSTQPDTEGIRHISL
                     NTVENSLQRSYITMDKDGDGHYDILSALQKSIRGSDVNASLHYAARLIEAGDLPSLAR
                     RLTIIAYEDIGLANPEAQIHTVTALEAAQKIGFPEARILIANVVIDLALSPKSNSAYM
                     AMDAALADLRQHGHLPIPRHLRDGHYAGSKELGNAQHYLYPHAYPEKWVKQQYLPDHL
                     VKKNYFNPNETGKYERALAANKARIDKLSSS"
     gene            complement(1283..1891)
                     /locus_tag="TVB59_000653"
     CDS             complement(1283..1891)
                     /locus_tag="TVB59_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEL1009582.1"
                     /translation="MILLIDNYDSFTYNLAQYLSAFDQTIVLTNQDPKLFDLAKQADA
                     IVLSPGPGWPKAANQMPSLIRAFYDQKPMLGVCLGHQAIAEALGGRLRLAKRVMHGKQ
                     SILERQAPAKLFQQLPKQLTVMRYHSIVVDDLPADFVITARDFEDNEIMAFEHRQLPL
                     FGLQFHPESIGTADGRTMIANFMAVVKKHHSQQKQGREEYNA"
     gene            complement(1932..3668)
                     /gene="pabB"
                     /locus_tag="TVB59_000654"
     CDS             complement(1932..3668)
                     /gene="pabB"
                     /locus_tag="TVB59_000654"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEL1009583.1"
                     /translation="MHIKTIIDFKELGQRYIFQAPIVELVAKQIDQVGQVLEQVNQFQ
                     DLGYYVVGYLSYEAAACFDKKLTTHNKRLGQEYFAYFTVHDSCQLEDFPLYHDSMTIP
                     NSWTSATQEEAYQEAIAQIHQEMRQGNTYQVNYTIQLSQRLNAKDSLAIYHQLVIEQA
                     AGYNAYIAHDDFAVISASPELFFKQEKNQITTRPMKGTTKRGYNLELDQQEHDWLQAD
                     PKNRSENMMIVDLLRNDMNKICQTGSVTVTQLCQLEQYSTVWQMTSTIVGMLQDQCRL
                     YDILQALFPCGSITGAPKVSTMAIINRLEPKPRGVYCGSIGICLPDGRRVFNVAIRTI
                     QLSYDQAIYGVGGGITWESCWQDEFEEIKQKSSFLNRQSIDFTIKTTAKVEQQSLIYL
                     DQHLNRLREAARYFAYPYDEELLTDRLQAYLKGKDSSPYRLTIAIAKDGQISLTDQSL
                     EPLQKDFLKARLVRQSSDVKKLPFTYFKTSHRPHLSVKPYEQVFVAADGTLLETSIGN
                     LFVQIEQTLYTPPVSAGILPGIFRQELLRQGLAQEKELKFSDLDKAEAIFGGNAVRGL
                     YSLTIEDTTLPQ"
     gene            3817..4287
                     /locus_tag="TVB59_000655"
     CDS             3817..4287
                     /locus_tag="TVB59_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEL1009584.1"
                     /translation="MAKYGFLSVLEEEMDKHFHYDYAMDWDKKNHAVEITLVLEAQNQ
                     SAVETIDDQGQLSKEDIVFEDYVLFYNPEKSQFQAADYLVAIPFEPKKGFSREFLAYF
                     AQFLNDVAIEGHSDLMDFLADDSKLDFSLEWNEEAFEEGQVGLEETELYSYPRY"
     gene            4289..4633
                     /locus_tag="TVB59_000656"
     CDS             4289..4633
                     /locus_tag="TVB59_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009910982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEL1009585.1"
                     /translation="MLHEMMLTPRPFAMIEAGVKTIELRLNDEKRQAIKVGDWICFYC
                     TEDHSHILQAEVVGLHYFDDFAKLYQALPLEKCGYRNEELALARPEDMEQYYSKEQQA
                     QYGVVGIELRLC"
     gene            4650..5078
                     /locus_tag="TVB59_000657"
     CDS             4650..5078
                     /locus_tag="TVB59_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEL1009586.1"
                     /translation="MKLLDKTVHFSGAKLALISNGKILTILRDAIPTIPYPNMWDLPG
                     GGRENAEAPFDCASRECYEELGLALTKDAVVWERVYPGLVNPDSQSVFLVALMNQDMI
                     DHIAFGDEGQGYQLMAIDDFLADDRVIPQLKARLADYLRK"
     gene            complement(5276..7813)
                     /locus_tag="TVB59_000658"
     CDS             complement(5276..7813)
                     /locus_tag="TVB59_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEL1009587.1"
                     /translation="MKQHQRFLSLVGLLLACNLALTACQTHSQKGHSQEPKKHQKATK
                     KKKQKSSKTAKKRERHQVPGIDVPTDDGFLLTSESQIERKTDTGIIVKHGDHKHFFFY
                     SDLKGTKWAYLIPKDYKEAQPASNQAARSGSVVSTGHAGDGYVFNPADIVAEDAYGYT
                     VRHGDHYHYILKSSLPSATINHIASTTPHFPSTPPSIHQQGGIPGIDFKTSDGFLFDG
                     TNISGVTDTGILVKHGNHLHPISFEDLKRSKWAYLVEQYKKKDHTKPQEGDYRAYIAY
                     LAKELKVDQARIKQVNVDGQVGFEYPHEDHTHVIWLKDIDLSKPFKTPEEQILKKIDG
                     ETFEQRKERLIKEFMDRFKVRREDISIEGNYMTISHGDHAHIYKIDPELPDDPERNVK
                     TESTNLEVETQLVYGPFYTENSSENLTRDGVYKKYHPEGIKNIKNFIHVLFSTNSEYG
                     DIEVNGIKTKRVHYLVRKDLDWKDLNIQRPEAIKHEGRIFKGWSAELPTAGKMDREHQ
                     RFYVDFDKVRKQPTKAVYGPGDDVSDLDLENYVPVWFTTIFNGRLKLNGVTQGGFFYN
                     VRSGLTWKEAKEQGLVIPEPVPDPGYEFIEYRSGVNLANNFNLTDFAKRFSITQNEND
                     KVAFTGLFSAAFGTTAPYIGPYIAVNPDKPTDLEDPSRHPNYYFHDPRHYVAVAFKAG
                     EGGQLISRAGKGKTAVYLVRKGHSLHTAGILPPSVQPDAGYKRDYNKPIISTEEYDKE
                     VTEDIVYNVNFDKITNNDVTGNSNHSGNTWLPGDPLPKEPQTPNHTGSTGSWLEEFVA
                     PVSDSDEDDLLAPDPELVGKTPVSDKPASYFLGESETASSTSVASNS"
     gene            8376..9329
                     /locus_tag="TVB59_000659"
     CDS             8376..9329
                     /locus_tag="TVB59_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEL1009588.1"
                     /translation="MKAWQELTITVHREAEEAVSNLLIEAGSQGVAINDTADYIGQED
                     RFGELYPAVEQSEMVTITAYYPSSADIDDIRQTINQGLNRLKQCDVELGELTLTNQEL
                     AEEDWADNWKAYYEPARITHDLTIVPSWTDYEATAGEKIIRLDPGMAFGTGTHPTTKL
                     SLFALEQVLRGGETVIDVGTGSGVLSIASSLLGAKEVFAYDLDDVAVRVAKDNIALNQ
                     ATDNIHVAAGDLLKGLTQEADVIVANILADILVHVTADAYRLIKSEGYLIMSGIISEK
                     LDMVKQAALNAGFLLETHMLQGEWNALIFKKTDDLSGVIGG"
     gene            9329..10075
                     /locus_tag="TVB59_000660"
     CDS             9329..10075
                     /locus_tag="TVB59_000660"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEL1009589.1"
                     /translation="MQQYFIKGRAEKIVQLTDKDTIKHMFQVMRLTDKEELVLVFDDG
                     IKRLARVSDSSAYEVELIKELEENLEMPVEVTIASGFPKGDKLDVITQKATELGAAAI
                     WGFPADWSVVKWDSKKLAKKQEKLAKIALGAAEQSKRNRVPEIQLFDQKGELLKQLKQ
                     FDKCFIAYEEAAKAGERSTLARELAGLSPGQKVLFIFGPEGGISSKELASFKQAGAIT
                     VGLGPRIMRTETAPLYALSAVSYALELMSS"
     gene            10324..11328
                     /locus_tag="TVB59_000661"
     CDS             10324..11328
                     /locus_tag="TVB59_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1009590.1"
                     /translation="MVTIKDVARLAGVSPSTASRAINDSDMISQATKERVKKAMEALD
                     YSPNYSAQNLVKRKSNTVGIILPVREGQDSLGNNPFFMQIIQGIAAVCTDQGYMVALA
                     TGRSEAELLKNVQNMIRSGNIGKLIFLYSKTDDQVFDFVKRQRVDCVVVGQSTTKDPG
                     NAKFVNNNNHQAGYDAAAFLLQKGYEAIVYAYTDMAELVQAERYKGYAELMTSKALAA
                     QALCVTLKDDRKSQKQLLDQLAKRSKVAFVVCDDVLAIHLQRLIKQVAADTQLAIVSF
                     NNSVLAELASPALTSIAIFPYQLGEQAAELVLSSAAPSPQPVLVPHQIIERESTPFIV
                     "
     gene            11625..13811
                     /locus_tag="TVB59_000662"
     CDS             11625..13811
                     /locus_tag="TVB59_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEL1009591.1"
                     /translation="MKTSFKQFFSFEFWQKFGKCLMVVIAVMPAAGLMVSIGNSLPML
                     NQESQLLATLGNVIAQVGWAVIGNLHLLFALAIGGSWAKERAGGAFASGLAFVLINRI
                     TGAIYGVSSAMLTDPEAKIKSLLGTEMIVKDYFTSVLESPALNTGVFVGIIAGFVGAT
                     AYNKYYNYRKLPDVLAFFNGKRFVPFVVILRSALVALVLALIWPVIQSGINGFGMWIA
                     SSQDTAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYEVMTGAAAGTKVFGQ
                     DPLWLAWVTDLVNLKGSNASTYQHLMETVVPARFKVGQMIGATGTLMGVALAMYRNVD
                     ADKKHKYKMMFISAAAAVFLTGVTEPLEYMFMFAAMPLYLVYALVQGASFAMADLVNL
                     RVHSFGNIELLTRTPMAIKAGLGMDLINFVWVSILFAVIMYVIADFMIKKMKLATAGR
                     LGNYDADILENDDTKPLSQQSIDGQSQVVQIINLLGGRENIADVDACMTRLRVTVNDP
                     SKVGSEEHWKQAGAMGLIIKGSGIQAVYGPKADILKSDIQDLLDSGAVIPEPKPAQPA
                     ASSSQQTDFKNLTEAVLAVADGEVLPITAVSDQVFAAKMMGDGFAVEPANGAIYAPVT
                     GLVTHVFPTKHAFGLLTDSGLEVLVHVGLDTVDLNGEPFTVKVSEGQRVSAGDLLAEA
                     DLTAITAAGRKTTVVVAFTNTTSIKAVNLVATGQQKAKTLVAQVEL"
     gene            13889..14710
                     /locus_tag="TVB59_000663"
     CDS             13889..14710
                     /locus_tag="TVB59_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEL1009592.1"
                     /translation="MTKLLTLNTHSWMEANALKKLFDLAEHILAQNYDVICLQEINQL
                     IDSEAAVPLSGYQPIAGTPAIHQDNFALLLVNYLKKRGQSYYWSWAYNHIGYDIYHEG
                     VAILSKQPIQASDILVSAVADEYDYHTRRALLAKTTIDGREAAVVSLHLSWFDQGFVG
                     EWQRLEAALQQLACPVLLLGDFNNPSGQEGYEMILKSPLDLQDSHQAADYVFGDHSIV
                     AAIDGWEDNKEAFKVDHVFTSKVFTINSSKVTFDGGEAPVVSDHYGLEVDLSWKL"
     gene            complement(15006..15464)
                     /gene="nrdI"
                     /locus_tag="TVB59_000664"
     CDS             complement(15006..15464)
                     /gene="nrdI"
                     /locus_tag="TVB59_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEL1009593.1"
                     /translation="MTDLTLVFISLSGNTLSFVRRLSQYLAEKHHIQTKAINIKELHH
                     ETFPVKESFVAILPTYLEGGNGIDSGEVEILTNPLGDFIAAHDNAKRCLGIIGSGNKN
                     FNHQYCLTAKQYAKRFGFPMLGDFELRGTSADIERLAQVIVARLTDDQQS"
     gene            complement(15860..17044)
                     /gene="sezV"
                     /locus_tag="TVB59_000665"
     CDS             complement(15860..17044)
                     /gene="sezV"
                     /locus_tag="TVB59_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_038674722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="surface antigen transcriptional activator SezV"
                     /protein_id="HEL1009594.1"
                     /translation="MDTMSLVKSLQGCLKLSITVFDKDHQVTESFWNDDTFEFYYRFQ
                     AVLRQMDKEQATNLFFQGSYNELFLIYRYQDHYILIGPWRCNVLDKTFFKVAVADKDL
                     TKEEEEILYQALKHLPVYPLNAIRDLLIVVHYFFSGKIEDLLSPPLRHYIRDFSDNIE
                     VQKANMFVKKQESKVCLYNYEKNLSSIVQEGDVHKLKEIIFSLRNTFIPVVSGDTLRS
                     EKNYSIIAFDRLAQIAIQSGMDIADAYHSREEFMRDSELATSMPDVLKIRDASLVFYT
                     QKVSELRDNRWKHVSPTVNAIIQYISVNLHKSVTTAELAQHFNMSESKLRQIFKRDTG
                     LTIYQYTSNMKIEEAKTLLRSAYAINHISDVLGFTDPSHFSKFFKKHTGESPKTYQNR
                     KH"
     gene            17294..18898
                     /locus_tag="TVB59_000666"
     CDS             17294..18898
                     /locus_tag="TVB59_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_156117153.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEL1009595.1"
                     /translation="MFLRNNKQKFSIRKLSAGAASVLVATSVLGGTTVKANSEVSRTA
                     TPRLSRDLKNRLNDIAISRDASSAQKVRNLLKGASVGDLQALLRGLDSARAAYGKDDY
                     YNLLMHLSSMLNDKPDGDRRQLSLASLLVDEIEKRIADGDSYAKLLEAKLAAIKSQQE
                     MLRERDSQLRNLEKEKEQELQKAKDERQALTESFNKTLSRSTKEYNKLKTELAKEKEK
                     AAKMTKELADKLSNAEASRDKAFAVSKDLADKLSSAEASRDKAFAVSKDLADKLAAKT
                     AEAEKLMENVGSLDRLVESAKREMAQKLAEIDQLTADKAKADAELAAANDTIASLQTE
                     LEKAKTELAVSERLIESGKREIAELQKQKDASDKALVESQANVAELEKQKAASDAKVA
                     ELEKEVEAAKAEVADLKAQLAKKEEELEAVKKEKEALEAKIEELKKAHAEELSKLKEM
                     LEKKDHANADLQAEINRLKQELADRIKSLSQGGRASQTNPGTTTAKAGQLPSTGESAN
                     PFFTIAALTVIAGAGMAVVSPKRKEN"
     gene            19121..21340
                     /locus_tag="TVB59_000667"
     CDS             19121..21340
                     /locus_tag="TVB59_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEL1009596.1"
                     /translation="MVKEINLSGEEVVALAAKYMTDGDVELVQKALDYATAAHFYQVR
                     KSGEPYIVHPIQVAAILADLHLDAVTVVCGFLHDVVEDTDITLEDIEFDFGKDVRDIV
                     DGVTKLGKVEYKSHEEQLAENHRKMLMAMSKDIRVILVKLADRLHNMRTLKHLRKDKQ
                     ERISRETMEIYAPLAHRLGISRIKWELEDLAFRYLNEIEFYKISHMMREKRREREALV
                     DDIVTKIKAYTTDQGLYGDVYGRPKHIYSVYRKMRDKKKRFDQIFDLIAIRCVMETQS
                     DVYAMVGYIHELWRPMPGRFKDYIAAPKTNGYQSIHTTVYGPKGPIEIQIRTKEMHQV
                     AEYGVAAHWAYKKGIRGKVNQVEQKVGMNWIKELVELQAASNGDAKGFVDSVKEDIFS
                     ERIYVFTPTGAVQELPKDSGPIDFAYAVHTQVGEKATGAKVNGRMVPLTAKLKTGDVV
                     EIVTNPNSFGPSRDWIKLVKTNKARNKIRQFFKNQDKELSINKGRELLVSYFQEQGYV
                     ANKYLERKRIEEILPKVSVKSEESLYAAVGFGDISPVSVFNKLTERERREEERAKAKA
                     EAEELVKGGEVKHENKEILKVRSENGVIIQGASGLLMRIAKCCNPVPGDVIEGYITKG
                     RGIAIHRADCNNIKSQDGYQERLIEVEWDLEHSSKDYQAEIDIYGLNRIGLLNDVLQI
                     LSNATKSISTVNAQPTKDMKFANIHVSFGIPNLAQLTAVVEKVKAVPDVYSVKRTNG"
     gene            21355..21798
                     /locus_tag="TVB59_000668"
     CDS             21355..21798
                     /locus_tag="TVB59_000668"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEL1009597.1"
                     /translation="MKIVIQRVKEASVSIDGKIAGAIDQGLLLLVGIGPDDQAEDIDY
                     AVRKISHMRIFSDPEGKMNRSIQDIEGSVLSISQFTLYADTKKGNRPAFTGAAKPDRA
                     SQLYNSFNAQLEQLVPVQRGVFGADMQVSLINDGPVTIILDTKYR"
     gene            complement(21925..23217)
                     /locus_tag="TVB59_000669"
     CDS             complement(21925..23217)
                     /locus_tag="TVB59_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HEL1009598.1"
                     /translation="MLTSKRLYHLGKTPLEIGTVVIGLFTMTLGAPAVKANHYKVGWA
                     WSSSSRVANHYKYEDTTKPIHSKDYQETTGLYLMVNITGVDNTNHTIVSPHYQDIRLE
                     YGKTYTTNEMIKLVQDVIDPSAESFKVISLKNAKLTKASTAEILSTDHFTTPIKGQYH
                     QKDQTYILTGQVLVEKVSKVALKDIKVTDKAGNPIQDSDAVAVTQHVKFLKKDNGQLV
                     NVDVTDSLGKEGLTGLRYYGSRVSSEELFEAAKKAFETTQAFKDGYQLVKRISTTVTQ
                     DPDITHQSHNGEIYSGASERMVYHADRDEDFNYIIDSNRIAQVYNSKYDVNNPISYAT
                     HSDSVVETYFISKDINDDYSTTYRSVTIYQQDKQQQLINEYTFKTHEAITTETIDKYL
                     KGLPNTFQAKNGTSYQFTGSLTPISETEFIAVYKDLQK"
     gene            23972..24820
                     /locus_tag="TVB59_000670"
     CDS             23972..24820
                     /locus_tag="TVB59_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEL1009599.1"
                     /translation="MALKDYFPDMQEGAFPLADQDWISVEVGEQYLHFPKSSLSEREQ
                     LLLGLGRQRKEPSKDQKSPWYHYLILGQGEQPEEFQGCQFIYINHQCPLAGDLIELLK
                     GIIEGVEAVLPISQTRTAFLVCHHSRSDLFQLLANLLPTIESDFGLALMIFIGNGWYQ
                     VSGNALRDYFKEENAVFTAYLAEHSASRLLTFSEVMLWSLLANSGLPALSKHFSQLLL
                     ANKEVMDLVLAMWQEHGNLVQTAQRLYIHRNSLQYKLDKFAQQSGLYLKQLDDLAFAY
                     LFILKH"
     gene            24970..26103
                     /gene="ugpC"
                     /locus_tag="TVB59_000671"
     CDS             24970..26103
                     /gene="ugpC"
                     /locus_tag="TVB59_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEL1009600.1"
                     /translation="MVELNLKHIYKKYPNTTHYAVEDFDLDIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELKIDGEVVNDKSPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYKKDDIDRRVKEAAEILGLTEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGSTTIYVTHDQTEAMTLADRIVIMSATKNPQGN
                     GTIGKIEQVGSPQELYNLPANKFVAGFIGSPAMNFFEVVVKDGQIISEDGLDIAIPEG
                     QAKMLEAAGYKGKKVIFGIRPEDISSNQIVHDTYPNANVTAEVLVSELLGSETMLYVK
                     LGQTEFASRVDARDFHNPGEKVSLTFNVAKGHFFDLETEQAIR"
     gene            26287..27906
                     /locus_tag="TVB59_000672"
     CDS             26287..27906
                     /locus_tag="TVB59_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEL1009601.1"
                     /translation="MEKHWWHKATIYQIYPRSFMDTSGNGIGDLKGITGKLDYLQELG
                     ITAIWLSPVYQSPMDDNGYDISDYQAIAAIFGDMADMDELLDEAKQRGIKIIMDLVVN
                     HTSDEHAWFVEARENPDSPKRDYYIWRDQPNNLMSIFSGSAWEYDDASGQYYLHIFSK
                     KQPDLNWENAELRQSIYDMMNFWIDKGIGGFRMDVIDLIGKIPDSEITGNGPRLHEYL
                     KEMNQASFGNHDLMTVGETWGATPEIARQYSRPENKELSMVFQFEHIGLQHKPNASKW
                     DYAAELNVPALKEIFSKWQTELKLGEGWNSLFWNNHDLPRVVSIWGNDTVYREKSAKA
                     MAILLHLMRGTPYIYQGEEIGMTNYPFERLSDVNDIESLNYAKEAMANGMSEEAVLDC
                     ICRVGRDNARTPMQWSSQKNAGFSTADQTWLPVNPNHQEINVASALADPDSVFYTYQK
                     LIQLRQTQDWLVEADYQLLETSDKVFAYKRQLGRETYLVVVNLSNQEQFFEESLHKAQ
                     VIISNTDVQAVVESQQLEPWDAFCVKLDETL"
     gene            28015..28377
                     /gene="traF"
                     /locus_tag="TVB59_000673"
                     /pseudo
     CDS             28015..28377
                     /gene="traF"
                     /locus_tag="TVB59_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623564.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraF"
     gene            28491..28850
                     /gene="yajC"
                     /locus_tag="TVB59_000674"
     CDS             28491..28850
                     /gene="yajC"
                     /locus_tag="TVB59_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEL1009602.1"
                     /translation="MGLPTILMFVVMIGLIWFMQRQQKKQAQERQNQLNAIEKGDEIV
                     TIGGMFAVVDEVDLAAKRIVLDVDGVYLPFELSAIKRVVEKGSAVTSADVDTTETAVD
                     DTAVEASDEAESAIETN"
     gene            29024..29773
                     /locus_tag="TVB59_000675"
     CDS             29024..29773
                     /locus_tag="TVB59_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEL1009603.1"
                     /translation="MFGLKAKSKKIVLDRIPKHIGIIMDGNGRWAKKRLKPRVFGHKA
                     GMDALQEVTIAASDLGVKVLTVYAFSTENWSRPQDEVSFIMNLPVEFFDKYVPELHKN
                     NVKVQMIGETNRLPKDTLKALEAAIAKTRQNTGLILNFALNYGGRAEITNAVGLIAQD
                     VLDAKLNPGDITEDLIANYLMTDHLPYLYRDPDLIIRTSGELRLSNFMPWQSAYSELY
                     FTPVLWPDFKRAELLKAIEDYNHRHRRFGAI"
     gene            29783..30577
                     /locus_tag="TVB59_000676"
     CDS             29783..30577
                     /locus_tag="TVB59_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEL1009604.1"
                     /translation="MRERFIWGGVAAAVFLPFLLIGSLPFQLFVGVLAMIGVSELLRM
                     KRLEVFSFEGVFAMLAAFVLTVPLDHYLTFLPMDASFACYGLLVFFLLAGIVISSDSY
                     GFEDASFPIAASLYVGIGFHNLVNARMTGIDKVFLALFIVWATDIGAYLIGRRFGKRK
                     LLPKISPNKTIEGSLGGIVSAVLVSFVFMLFDKAVYAPHHFGTMLILVALFSIFAQFG
                     DLVESAVKRHFGVKDSGKLIPGHGGILDRFDSMIFVFPIMHLFGLF"
     gene            30609..31874
                     /gene="rseP"
                     /locus_tag="TVB59_000677"
     CDS             30609..31874
                     /gene="rseP"
                     /locus_tag="TVB59_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEL1009605.1"
                     /translation="MLGIITFIIIFGILVLVHEFGHFYFAKRSGILVREFAIGMGPKL
                     FSHVDQQGTLYTIRLLPLGGYVRMAGWGDDTTEIKTGTPASLTLNDQGLVKRINLSQS
                     KLDPTSLPMNVTAYDLEDKLTITGLVLDEIKTYSVDHDATIVEEDGTEIRIAPLDVQY
                     QNASIGGRLITNFAGPMNNFILGIVVFILFAFVQGGVADYHSNHIRVVENGAAAKAGI
                     RDNDQILEINHQKINDWYELTQAVTDSAADVKAKGKLEITYQTGDQVKTIALKPEKKG
                     DQYLIGVQYPLKTSLTDKLIGGFEMAGNGALVIVTALKSLITSFSLDKLGGPVAMYQM
                     SNQAAKNGLESVLSLMAMLSINLGIFNLIPIPALDGGKILMNVIEALRRKPLKQETET
                     YITLAGVAIMVVLMIAVTWNDIMRAFFQG"
     gene            32144..34000
                     /locus_tag="TVB59_000678"
     CDS             32144..34000
                     /locus_tag="TVB59_000678"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEL1009606.1"
                     /translation="MKQSKMLIPTLREMPSDAQVISHALMVRAGYVRQVSAGIYAYLP
                     LAHRTIEKFKTIMRQEFDKIGAVEMLAPALLTADLWRESGRYETYGEDLYKLKNRDKS
                     DFILGPTHEETFTTLVRDAVKSYKQLPLNLYQIQSKYRDEKRPRNGLLRTREFIMKDG
                     YSFHQSYDDLDVTYDAYRQAYEAIFTRAGLDFKGIIGDGGAMGGKDSQEFMAITPDRT
                     NLDRWLVLDKSIPSLADIPEEVLEEIKAELASWLVSGEDTIAYSSESSYAANLEMATS
                     EYKSSSKVTALDDLVEIETPNCKTIDEVAAFLDVAEHQVIKTLLFMVDHEPVLALLVG
                     NDQINAVKLKNHLGADFLEPASEEEARAILGAGFGSLGPVHLTDGIRIVADRKVQDLA
                     NAVAGANKDGYHLTGVNPNRDFQAEYADIREVKEGETSPDRHGVLQFARGIEIGHIFK
                     LGTRYSDSMAANILDENGRAVPIVMGCYGIGVSRILSAVIEQHARLFVSKTPKGDYRY
                     AWGINFPKELAPFDVHLITVNVKDQEAQDLTERVEASLMAKGYDVLTDDRNERVGSKF
                     SDSDLIGLPIRVTIGKKAAEGIVEIKIKATGDSIEVHADSLIETLDILTKDN"
     gene            34052..34609
                     /locus_tag="TVB59_000679"
     CDS             34052..34609
                     /locus_tag="TVB59_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEL1009607.1"
                     /translation="MTIEELQQLVLADHELMTILSIIETLPLKDCWLAAGAIRNAIWN
                     HLAYGIGFDPLTDVDVVFFDPEISYEAEQLLEEQLKCAYPMYQWEVRNQAYMAAHNPK
                     TPPYRSSQDAITKYPERCTAIAVRLVGGQLEVFAPYGLADISHFVCRPTPHFLEDSER
                     MDCYRQRLAKKDWHKKWPQLTYHDC"
     gene            34944..39341
                     /locus_tag="TVB59_000680"
     CDS             34944..39341
                     /locus_tag="TVB59_000680"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEL1009608.1"
                     /translation="MSDLFGKLMEQIEMPLEIRQSSAFSSADIIEVKVHSVSRLWEFH
                     FSFAEVLPIESYRELSDRLVRTFEAADIKVTFDIKAETINYSDQLLQAYYQEAFEHEP
                     CNGASFKSSFSRLQVRYDHHQLIIMAPDFVNNDHFRKNHLPNLAAQFERFGFGRLAID
                     MVSDQEMTDHLTKDFETNRQALVEKAVQDNIAAQQSLEAMQPPAEEAAPSPSLDYRER
                     MAQRQASFDKAVITPMIEVDTEENRIVFEGMVFDVERKTTRTGRHIINFKMTDYTSSF
                     AMQKWAKDDDELRKFDLIAKGAWLRVQGNIENNPFTKSLTMNVQQVKAIVHHERKDLM
                     PEGQKRVEFHAHTNMSTMDALPTVEDLIDTAARWGHQAVAITDHANVQSFPHGYHRAR
                     KAGIKAIFGLEANIVEDKVPISFNPVAMDLHEATYVVFDVETTGLSAMNNDLIQIAAS
                     KMFKGNIIEQFDEFINPGHPLSAFTTELTGITDNHLVGAKPIQQVLEAFQAFCQGTIL
                     VAHNASFDVGFMNANYDRYGLAKISQPVIDTLELARNLYPEYKRHGLGPLTKRFQVSL
                     EHHHMANYDAEATGRLLFIFLKEAREKHGITNLLQLNTDLVAEDSYKKARIKHATIYV
                     QNQLGLKNMFKLVSLSNVKYFEGVPRIPRTVLDQHREGLLLGTACSDGEVFDAVLTQG
                     IDAAVDLAKYYDFIEIMPPAIYQPLVVRELIKDQAGVEQIIRDLIEVGRRAEKPVLAT
                     GNVHYIEPEDAIYRDIIVRSLGQGALINRTIGRGEAAKPVPLPEAHFRTTNEMLDDFA
                     FLGQDLAYEVVVQNTQALADRIEKVEVVKDDLYTPYIDKAEETVAELTYQKAFAIYGN
                     PLPDIIDLRIEKELTSILGNGFAVIYLASQMLVNRSNERGYLVGSRGSVGSSFVATMI
                     GITEVNPMPPHYVCPSCQQSEFITDGSVGSGYDLPNKACPRCGTLYKKDGQDIPFETF
                     LGFDGDKVPDIDLNFSGDDQPNAHLDVRDIFGEEYAFRAGTVGTVAEKTAYGFVKGYE
                     RDYGKFYPDAEVDRLAAGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQFPADDVTAS
                     WQTTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPITIPADDPDVMALFSGTE
                     VLGVTPEQIGTPTGMLGIPEFGTNFVRGMVNETHPTTFAELLQLSGLSHGTDVWLGNA
                     QDLIKEGIATLKTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERSSY
                     IKAMRQNNVPDWYIESCGKIKYMFPKAHAAAYVLMALRVAYFKVHHPIMYYCAYFSIR
                     AKAFELKTMSGGLAAVKARMEDISNKRKRNEASNVENDLFTTLEIVNEMLERGFKFGK
                     LDLYKSEATEFQIEGDTLIPPFIALEGLGENVARQIVKARQDGEFLSKMELRKRGGAS
                     ATLVDKMDELGILGNMPDDNQLSLFDDFF"
     gene            39463..39891
                     /locus_tag="TVB59_000681"
     CDS             39463..39891
                     /locus_tag="TVB59_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEL1009609.1"
                     /translation="MNELDKNPALKAMVVFRKAQRTLDAQSSAFFQKANLTPTQFSVL
                     EVLYSKGSMRINKLIGSLLATSGNMTVVLKNMERNGWISRCQDAKDKRACLVQLTPEG
                     KALIETILPEHIKRVEALFSVLTETEQKQLITLLKKFKEL"
     gene            40021..40566
                     /locus_tag="TVB59_000682"
     CDS             40021..40566
                     /locus_tag="TVB59_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEL1009610.1"
                     /translation="MKQILIINGSLRTGSFNHQLAQAAEQLLEGKAAVSYLDWEQVPM
                     FSQDLEASTPESVAGVREAIQAADAIWIFSPVYNFAIPGSIKNLLDWVSRALDLSDPS
                     GPSAINGKVVTVSSVANGGHEQLFAQYQDLLPFIRTTVVGNFTKAAVNPEAWATGVLD
                     ISEETRQSLAAQAEALLEAIH"
     gene            complement(40745..41359)
                     /locus_tag="TVB59_000683"
     CDS             complement(40745..41359)
                     /locus_tag="TVB59_000683"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEL1009611.1"
                     /translation="MSAQDKLIKAQHLIDMNDIIREGNPTLRAVAKEVEFPLSDDDII
                     LGEKMMQFLKHSQDPVMGEKLGLRAGVGLAAPQIDVSKRIIAVLVPNPEDSEGNPPKE
                     AYSMEEVLYNPKIVSHSVQDAALADGEGCLSVDRVVEGYVVRHARVTVEYYDKHNEKH
                     RIKLKGYNAIVVQHEIDHINGVLFYDRINAKNPFEAKEGMLILN"
     gene            41724..43151
                     /locus_tag="TVB59_000684"
     CDS             41724..43151
                     /locus_tag="TVB59_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin binding protein"
                     /protein_id="HEL1009612.1"
                     /translation="MERLMRTQLKKLLAGTAAGTLLLFNLTCGMINAFAEQYYGWSDG
                     SSSYPSALYVTPVGDTTKKIAIPVYCFDYKFQEPLAWKEITQPSHLIVYDKYDGKNLM
                     AALVEKPNMVSYETKTKLQTLLKTKSNLITAILSRGYPNKSFFDKYKKLTDEDKRRVT
                     QCALWYHTDNISEQDLITKHLDGDSGEKSQALKELIGVVKNTSNELGEGLTFYTRYND
                     RYGPKYQNLIGSIIVPEEPQNDLEIGGGNVIDLNYQSGPMVEEGGHSGGKEEVEDTKK
                     PDVIIGGQGSVTETTEDTQKGMSGSTETQPEVEDTKQPQSDIILGGQGNVIDTTENTQ
                     EGMGGQSGDTTETEDTKQPQSDIILGGQGNVIDTTENTQEGMSGSNNGQTFEEDTRPK
                     LEFHFDNEVPNDDDAPKPEQPEQPEKPEQPRKPQQEQQSLPRPIEGNQSLPKTHEAKG
                     VLALVGVGILAMLGLGFWFRPYQKD"
     gene            43417..43686
                     /gene="rpsO"
                     /locus_tag="TVB59_000685"
     CDS             43417..43686
                     /gene="rpsO"
                     /locus_tag="TVB59_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEL1009613.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNNHIK
                     EHKKDHATYRGLMKKIGHRRNLLAYLRRTDVNRYRELIQSLGLRR"
BASE COUNT        12342 a         8707 c        10420 g        12311 t
ORIGIN      
        1 cttgtttttt tctttaggct agctgctaga aagcttatca attcgcgctt tattggcggc
       61 taaggctctt tcatattttc ctgtttcatt tgggttgaag taatttttct taaccaagtg
      121 atcagggaga tattgctgct tgacccattt ttctggatat gcatgagggt aaaggtagtg
      181 ctgagcattg cctagctcct tgctgccggc ataatgccca tcacgcaggt gtctaggaat
      241 gggaagatgg ccatgttgac gtaaatcagc gagagcagcg tccatagcca tataggcgga
      301 attggacttt ggtgacagtg ctagatcaat cacaacattg gcaatgagga tacgcgcctc
      361 tgggaagcca attttctggg cggcctcaag tgcagtgacg gtatggattt gagcttctgg
      421 attggcaaga cctatgtcct cataggcgat aatggtcaag cgtctagcaa gactcggaag
      481 atcgcctgcc tcaataagcc ttgcagcata gtgcaagcta gcattaacat cagatcctcg
      541 gattgatttt tgcaaggcag atagtatgtc ataatgtccg tcgccatctt tgtccattgt
      601 gatgtagctg cgctgcaaag aattttcaac agtattcaag ctgatatgac ggataccctc
      661 ggtatctggc tgggttgaca tgacagctag atcaagggat tggtaggcgg ctcggagatc
      721 tccatttgtc gctgtcgcaa taaagtcaaa agcagcctca tctagggtca catcaaaggc
      781 aaagcctctc tccttatcag tgatggcaag cttaagcgcc tgcttgatct cctcaggtga
      841 taggggctcc agctcaaaaa tctggactcg acttctgatg gctggagtaa ccgagaaaaa
      901 aggattccct gtggtagcac caatcataat aatgtgccca tgctctaaaa gtggtagtaa
      961 aaagtcctgc ttactcttat ccaatcggtg aatttcatca agcaaaagca caagtccacc
     1021 tgaaaactta gcttcctcag cgatttcttg gaggcgtttt ttattgtcta tggtagcatt
     1081 gaaggttcta aaggcgtact tggttgttcc agcaatagca ctagcaattg atgtctttcc
     1141 aataccggga ggtccgtaaa gaatcattga ggctaatcta ttggccttga ccatgcggtc
     1201 aatgattttt ccctccccga ccagatgctg ctggccgatg acctctgtaa tggttctagg
     1261 gcgcattctg atggctagat tatcaggcat tgtattcctc ccttccttgc ttttgttggc
     1321 tgtggtgctt tttaacaaca gccataaagt ttgcgatcat tgtcctaccg tcagctgttc
     1381 cgatgctttc tgggtgaaat tgaaggccaa acagtggcag ctgtctgtgt tcaaaggcca
     1441 taatctcatt gtcctcaaag tctcttgcgg taattacaaa gtcagctggc aggtcatcaa
     1501 caacaataga atggtaacgc atgacggtta attgctttgg cagctgttga aagagcttag
     1561 ctggtgcttg tctttcaagt atactttgct tgccatgcat gacgcgctta gcaaggcgta
     1621 gcctgccacc tagagcctca gcgatagctt ggtggccaag gcaaacgcca agcataggct
     1681 tttggtcata aaaggcccta atcaagctag gcatctgatt ggcggctttg ggccagccgg
     1741 gtccaggtga gaggactatg gcgtcagcct gcttcgcaag gtcaaatagt tttggatcct
     1801 gattggtcaa tacaatcgtt tgatcaaagg cactgaggta ttgggccaga ttataggtaa
     1861 atgaatcgta gttatcaatt aaaagtatca taaggtcctt catctagtag tgctgaggga
     1921 tcagcctggt actattgagg cagagtggtg tcctcaattg ttagtgagta gagtcctcgg
     1981 acagcattgc caccaaaaat ggcttcggcc ttgtctaaat ctgaaaactt tagctctttt
     2041 tcctgagcca gtccctgcct tagtaattct tgacggaaaa tgcctggtag aataccggct
     2101 gatacaggcg gtgtataaag ggtctgctcg atttgcacaa aaagattacc aatagaggtt
     2161 tcaagcaagg tcccatcagc agcaacaaag acttgctcat aaggcttgac gctcagatgt
     2221 ggtcgatgac tggttttaaa ataagtaaag ggaagctttt tgacatcgct tgattggcga
     2281 actaatcgtg cctttaaaaa gtctttttga agcggctcta agctttggtc tgtaaggcta
     2341 atctgcccgt ccttagcaat agcaatagtg agacgatagg ggctgctgtc ctttcccttg
     2401 agataggctt gcaaacgatc tgtcagaagc tcttcgtcat aggggtaggc aaaataacgc
     2461 gccgcctccc ttagtctgtt gaggtgctgg tctagatata ttaggctttg ttgttcgacc
     2521 ttggcagtgg ttttgatggt gaaatcaatg ctttgacggt tcagaaagga agatttttgc
     2581 ttgatttctt caaattcgtc ctgccagcag ctttcccagg taatcccacc gcctaccccg
     2641 tagatggcct gatcgtagct gagctgaatc gttcgaatag cgacattgaa gacacgtctg
     2701 ccatcaggca ggcaaatacc aatgctgcca cagtaaacgc cccttggctt aggctctaat
     2761 cggttaataa tagccattgt agacacctta ggagctcctg tgatggagcc acagggaaag
     2821 agtgcctgta aaatatcata aagacgacac tgatcctgca gcatgccgac aatggtagag
     2881 gtcatctgcc aaacggtgga atattgctcc aattggcaga gctgtgtgac tgtgacactc
     2941 ccagtttgac agatcttatt catatcattg cgtaataaat caacgatcat catgttttct
     3001 gaacggttct taggatcggc ctgtagccag tcatgctctt gttgatctag ttctaaattg
     3061 taaccacgct tggttgtgcc tttcatgggg cgtgtggtga tctggttttt ctcttgcttg
     3121 aaaaataact caggactggc tgaaatgaca gcaaagtcat cgtgagcaat gtaggcattg
     3181 tatccagctg cctgttcaat gaccaattga tgataaatgg ccaagctgtc cttagcgttt
     3241 agcctttggc tgagctgaat ggtatagttg acctgatagg tattgccctg cctcatctcc
     3301 tgatgaatct gtgcaatagc ctcttgatag gcttcctctt gtgtagcact tgtccagctg
     3361 tttggaatcg tcatgctgtc gtggtagagc ggaaagtcct cgagctgaca gctgtcatgc
     3421 actgtaaaat aagcaaaata ttcctgacca agtcttttat tgtgtgttgt tagctttttg
     3481 tcaaaacagg ctgctgcttc atagctgagg tagcccacaa catagtagcc cagatcttga
     3541 aattggttga cctgctcaag gacctgtccc acctgatcaa tctgcttagc tactaattcc
     3601 acgataggag cttgaaatat atagcgttgt cccagctcct taaaatcaat aatcgtcttt
     3661 atatgcatag cttgattata tcataaatgc gcttttcaga ctgattagga gggttgaaaa
     3721 gaagcctgtt agcaaccatc aacaatacaa gagagcaggg cttcttgatt tatgctacaa
     3781 tagtagcgga tattatttag aaaaaggaac aagagcatgg ctaaatatgg ctttttatca
     3841 gtattagaag aagagatgga caagcatttt cattatgact atgctatgga ttgggacaag
     3901 aaaaatcatg cggttgaaat cacccttgtt ttagaggctc aaaatcagtc agcagttgaa
     3961 accattgatg accaaggaca gctcagcaag gaagacattg tctttgagga ttatgtctta
     4021 ttttacaatc cggagaaatc acagtttcaa gcagcagact atctggtggc tattccattt
     4081 gagccaaaaa agggcttttc tcgtgaattt ttagcctatt ttgcccagtt tctcaatgat
     4141 gttgccattg aagggcatag cgatttgatg gatttcttag cagatgatag caagcttgat
     4201 tttagtctag agtggaacga ggaggccttt gaggaagggc aggtaggact agaggaaaca
     4261 gagctttata gctatccgag gtattaagat gctacatgag atgatgctga caccaagacc
     4321 atttgctatg attgaggcgg gtgtgaagac tattgaacta cggttaaatg atgagaaaag
     4381 gcaggctatt aaggtagggg attggatttg cttttattgt acagaggatc atagccatat
     4441 tctgcaagca gaggtcgtag ggttgcatta ttttgatgac tttgctaagc tttaccaagc
     4501 attgccttta gaaaaatgtg gttatcgtaa tgaagaattg gcactggctc ggccggagga
     4561 tatggaacag tactacagca aagagcagca agcccaatat ggcgttgttg gtattgagct
     4621 aaggctatgt tgattggtga gatctagtca tgaagctttt agataaaaca gtccattttt
     4681 ctggtgcaaa gttagccttg atcagtaacg gtaagatttt gaccatcttg cgtgacgcga
     4741 taccaacgat tccttaccct aatatgtggg atttaccagg aggtggtcgt gaaaatgctg
     4801 aagctccctt tgattgtgcg tcacgtgagt gctatgagga gttaggtctg gcactgacta
     4861 aggacgctgt cgtttgggaa agggtttatc cagggcttgt taatcctgac agccaatctg
     4921 tctttctggt ggctcttatg aatcaggaca tgatagatca tattgctttt ggtgatgagg
     4981 ggcagggtta tcagctgatg gctattgatg actttttagc agacgatcgg gtcattcctc
     5041 agctaaaggc tcgcttagct gattatttaa ggaaataggc agacttagct ggtacactaa
     5101 acagatcagc aaacaccact actatgtgat agctacgacc agaatcaaaa agacgattga
     5161 cctctgccca catgtggcta ggatcaatcg tctttgtttt tggggtggct aagtctttaa
     5221 tctggtaggc cagatcagct gagtagttga tattatcaat cagtcctgct atggcttagc
     5281 tgttgctagc tactgatgtg ctgctagctg tctctgactc acctaaaaaa tagctggctg
     5341 gcttatcact tactggcgtc ttaccaacaa gctcagggtc aggtgctaat aggtcgtcct
     5401 cgtcggagtc agaaacgggc gctacaaatt cttctagcca gcttccagtg ctgccagtgt
     5461 gattaggagt ttgaggctcc ttaggtagtg gatcacctgg tagccaggta ttccctgagt
     5521 gattactatt acctgtaaca tcgttgttgg ttattttatc aaagttgacg ttataaacaa
     5581 tatcctcagt gacttcctta tcatattcct cagttgaaat aataggctta ttgtaatcac
     5641 gcttgtagcc ggcatctggc tgtactgatg gtggtaggat accagctgta tgtaatgagt
     5701 gtcccttacg aacaaggtaa acggcagtct tacccttacc agctcggcta atcagctgtc
     5761 cgccctctcc tgccttaaag gcaacggcta catagtgtct cggatcgtgg aagtaataat
     5821 tagggtgtct gctaggatcc tctagatcag ttggcttgtc aggattaaca gcgatgtaag
     5881 gtccaatata aggagcagta gttccaaagg ctgctgagaa taggccagta aaggctacct
     5941 tatcgttttc attttgtgtg atagaaaatc tcttagcaaa atcagttaga ttaaagttat
     6001 tggcaaggtt cactccactg cggtattcaa taaattcata gcctggatct gggacgggct
     6061 cagggataac aagtccttgc tccttagctt ccttccaggt aagaccacta cgaacattgt
     6121 agaagaagcc tccttgagtc acgccgttaa gcttcaatcg cccattaaag attgtggtga
     6181 accagacagg aacataattt tctaagtcaa ggtctgaaac atcatcacct ggcccgtaga
     6241 cagccttggt aggctgcttt ctaaccttat caaaatctac atagaagcgt tgatgttctc
     6301 tgtccatctt gccagctgtt ggcaactcag cactccagcc cttaaagata cgcccctcat
     6361 gcttgattgc ctctggacgc tgaatgttca aatccttcca gtccaaatcc ttacgaacca
     6421 aatagtgcac acgtttagtt ttaatgccat taacctcaat gtcgccgtat tcactatttg
     6481 tactaaacaa cacatggata aagtttttga tgtttttgat gccctctggg tgatattttt
     6541 tatagacccc atcacgtgtt agattttcag atgaattttc cgtatagaaa ggaccataaa
     6601 cgagctgagt ttcgacctct agattggttg attctgtctt gacattgcgc tcaggatcat
     6661 ctggcaattc tgggtcaatc ttatagatgt gagcatggtc cccatgacta atggtcatgt
     6721 agttgccctc aattgagatg tcctcacgac gaaccttgaa gcgatccata aattctttga
     6781 tgagtctttc tttgcgctgt tcaaaggttt ctccgtctat ctttttgagg atctgttctt
     6841 ctggagtttt aaatggctta gaaagatcaa tatcctttag ccagatgacg tgcgtgtggt
     6901 cctcatgagg gtattcaaag ccgacctgac cgtctacatt cacctgctta atgcgtgctt
     6961 gatctacctt tagctccttg gcgagataag ctatataggc gcgatagtct ccttcctgag
     7021 gcttggtgtg gtcctttttc ttatattgct ccactaaata agcccatttg ctacgcttta
     7081 agtcctcaaa gctaataggg tgcaaatggt tcccatgctt caccaggatt ccagtgtcag
     7141 tgacaccgct aatgttggtg ccatcaaata agaagccatc actagttttg aagtcaattc
     7201 ctgggatacc cccctgctga tgaatgctag gtggtgttga tgggaagtga ggtgtggttg
     7261 atgcgatgtg gttgatggtt gctgatggca ggcttgattt gaggatatag tggtaatgat
     7321 ctccatgacg aacagtgtag ccataggcgt cctcagcaac aatgtcagct ggattaaaga
     7381 catagccgtc tccagcatga ccagttgaga ctactgatcc agaccttgcc gcttggttag
     7441 aagcaggctg tgcttccttg taatccttag gaatcaggta agcccatttt gtccccttca
     7501 aatctgagta aaagaagaaa tgcttgtgat cgccatgctt cacaatgata cctgtatctg
     7561 ttttgcgttc aatttgcgat tcgctggtca ataaaaagcc atcatcagtt gggacatcaa
     7621 tcccagggac ttggtgacgt tctctttttt tcgcagtctt actgcttttt tgttttttct
     7681 ttttcgtagc cttttggtgc tttttaggct cctgagaatg tcccttttgc gaatgcgttt
     7741 ggcaggctgt taaggcaagg ttgcaggcta acagcagtcc aacgagggat aaaaatcgtt
     7801 gatgttgttt catggttagt tatcaactcc ttccaacaat taacttaacc agttaatatt
     7861 attactggtt aagtatatca tttgacatct aagaatacaa tagattttat aaatttttta
     7921 atgaaattaa tctaatgacc taagagctgt ctggaagatg aaaggctttt tagctatttc
     7981 aaaggcttgg agcttcaaca ggcgaatcag ctattggttt ttctggattt acgagaaaga
     8041 gctgctcttt tttgatgtag ctggtataaa atatggtaaa atagggtcta tcaagagcct
     8101 atctaccttt agattggctg agatttgtta ggcaatgcgt ccctgataaa ggttgggctt
     8161 atgggacaat aggccttggt gctgtgtttg tccttagtat gaaacctctg agacggcaga
     8221 gcaggatccg gttggtttag gaccgcatta gcttatctta cgataaaaaa gaagcttgaa
     8281 aggaaaggct gctttgatct gatagagggt cactggtttt agggtttagg ctaggggcaa
     8341 gtgaccactg atgatatggc agcaagggta tcgttatgaa ggcatggcaa gagctgacaa
     8401 ttacagtcca tcgtgaggca gaagaagctg tttccaatct gctgattgag gctggcagcc
     8461 aaggagtcgc tatcaatgac actgcagact atatcggtca agaggaccgt tttggggagc
     8521 tttatccagc tgttgagcag tcagaaatgg ttactattac agcctattat ccaagctcag
     8581 ctgatattga tgacatcaga cagaccatta atcagggctt gaacaggcta aagcagtgtg
     8641 atgtggagct tggtgagtta accctgacca atcaagaatt ggctgaagag gattgggcgg
     8701 acaactggaa agcctattat gagcctgctc gtatcacgca tgatttgacg atagtcccca
     8761 gttggacaga ttatgaagcc acagcaggtg agaagatcat taggcttgat ccgggtatgg
     8821 catttggaac aggcacacac ccaacaacta agctaagcct gtttgccttg gagcaggtgc
     8881 ttcgtggtgg tgagacagtt attgatgtgg ggacaggctc aggtgtgcta tcgattgcta
     8941 gctctctgct tggcgccaaa gaggtctttg cttatgattt agatgatgtg gcggtgcgtg
     9001 ttgccaaaga caacattgcc ctcaatcaag ccactgacaa tatccatgta gcagctggag
     9061 acctgctaaa aggccttact caagaggcag acgttattgt cgccaatatc ttggcggata
     9121 ttttggtgca tgtgacagca gatgcttacc gtcttatcaa gtctgagggg tatctgatca
     9181 tgtcagggat tatttcagaa aagctggata tggtgaagca ggctgctctt aatgcaggct
     9241 tcttgctaga gactcacatg cttcagggcg agtggaatgc tcttattttc aaaaaaacag
     9301 atgatttatc aggagtgatt ggtggctgat gcagcagtat tttattaaag gcagggcaga
     9361 aaaaatcgtt cagctgaccg ataaggatac cattaagcat atgtttcaag tgatgcgctt
     9421 gacggataag gaagagctgg tgctagtctt tgatgacggc attaaacgct tggcaagggt
     9481 gtcagacagc tcagcctatg aggtggagct tatcaaagag ctggaagaaa accttgaaat
     9541 gcctgttgag gtgactattg cctcaggctt tcccaagggt gataagctag atgttatcac
     9601 tcaaaaggcg actgagttag gggcagcagc tatttggggc tttccagcag actggtcggt
     9661 ggtcaagtgg gatagcaaga agctagctaa aaagcaagaa aaattagcta aaattgctct
     9721 tggagcagca gagcaatcca agcgtaatcg cgtaccggag attcaactat ttgaccaaaa
     9781 gggtgagcta ttaaagcagc ttaagcagtt tgataagtgc tttatcgctt atgaggaagc
     9841 agctaaggca ggtgaaaggt cgacattggc gcgtgagcta gcaggtctta gcccaggtca
     9901 aaaagtcctc tttatctttg gaccagaggg tggtatttct tcaaaagagc tggctagctt
     9961 taagcaagca ggtgctatta ctgtgggact ggggcctcgt atcatgcgga cagaaacagc
    10021 accgctctat gccttgagtg ctgttagcta tgctctggag ctaatgtcta gctgatagtg
    10081 ctaataggag acagcacctt gtggctcagt gcttgacaga aaaaagagga gcatctgcga
    10141 ttatgctaat aaagcaccgc ttaacaaaaa gatcgctaag aaggagactg ccgcaaatca
    10201 aagggctagt ctagcccgcg taggtgcaga gctgtcgggc ctttgcagct tcatttgtaa
    10261 aaaatataac aaatcatctc aaaataaaga tactcgtcaa acggattggt agaggaggga
    10321 catgtggtta cgataaaaga tgtggcaagg ctagcaggag tttcgccttc aacagcttcg
    10381 cgtgccatca atgacagtga catgattagt caggcgacaa aggagcgtgt caaaaaagcc
    10441 atggaggcct tggattattc gcctaattat tcggcgcaaa accttgttaa gcgaaagtcc
    10501 aatactgtcg ggatcatttt gccggtgcgt gagggtcagg attcactggg aaataaccct
    10561 tttttcatgc agattattca aggaattgct gctgtttgta ccgatcaggg ctacatggta
    10621 gcccttgcga ctggacgtag tgaggccgaa ttgctaaaaa acgtgcaaaa catgatccgt
    10681 agtggcaata ttggcaagct gatttttctt tattccaaaa cagatgatca ggtttttgac
    10741 tttgtcaaaa ggcaaagagt ggattgtgtt gtcgttgggc aatcaacgac aaaggatcct
    10801 ggcaatgcta aatttgtcaa caacaataac catcaagccg gctatgatgc agcagcattt
    10861 ctccttcaaa aaggctatga ggctattgtc tatgcttata ctgacatggc cgaattggtg
    10921 caggcagagc gttataaggg ctatgcagag ctgatgactt caaaggctct ggcagctcaa
    10981 gccctttgtg tcacgctaaa ggacgatagg aaaagtcaaa agcagctgtt agaccaatta
    11041 gccaagcgct ctaaagttgc ctttgtagtc tgtgatgatg tgctagctat tcatttgcag
    11101 cgtctcatca agcaagtagc agctgacacc cagctagcaa tcgttagctt caataattct
    11161 gtcctagcgg agcttgcgag tcctgccttg acctccattg ctatttttcc ctatcagctg
    11221 ggagagcaag ctgctgagct ggtcttatca agcgcagcgc catcaccaca gccagtctta
    11281 gttcctcatc agatcattga aagagagtct acgcctttta ttgtttgatt taccgttaag
    11341 cctattccta agcaaagtac tgatagcttg cttaggaata aggcttttta tttaggaatt
    11401 tattttgttt gctaatagta ttaaagagaa gcaacgttta ctttagcatt ttcattgaaa
    11461 tcttcttaag aaaacgcttt acaaaacaaa aaaaggttgg taaaataagc ttatcaaaag
    11521 cgcaaacgtt tgcgttgaat gtgcttgttt ttaaaaagga attgagagtt catcagcttt
    11581 tagctggtta ttcttgattc ctagtccaaa aaaggagagg tcgaatgaaa acatcattca
    11641 aacaattttt tagcttcgag ttttggcaaa aattcgggaa atgcttgatg gttgtcattg
    11701 ctgttatgcc tgctgcaggt ttaatggtga gtattggaaa ttctctgccc atgcttaatc
    11761 aggagtcgca gcttttagcg acgcttggta atgtcattgc tcaggttggt tgggcagtta
    11821 ttggtaacct tcatttgctt tttgcccttg ctattggtgg cagctgggct aaggagcgtg
    11881 ctggcggtgc ctttgcttca gggcttgctt ttgttttgat taaccgtatt acaggggcta
    11941 tctatggcgt ttcttcagcc atgctgactg atccagaggc caagattaaa agtcttttgg
    12001 gcactgagat gattgtcaag gactacttta caagcgtctt agagtcacct gctctaaata
    12061 ccggtgtctt tgttgggatt atcgctggct ttgtgggtgc aacagcctat aacaaatact
    12121 acaattaccg taagctgcct gatgtgctgg ctttctttaa tgggaaacgc tttgttcctt
    12181 ttgtagttat ccttcgttca gctcttgtgg ccctagtatt agccttgatt tggccagtta
    12241 ttcagtctgg tattaatggc tttggcatgt ggattgcctc atctcaggac acagctccaa
    12301 tccttgcgcc attcttatat ggaacattgg agcgtctctt gctgccattt ggccttcacc
    12361 acatgctaac gattccgatg aactatacag ctcttggggg cacctatgag gtcatgacag
    12421 gagcagctgc tggaactaag gtatttggtc aagaccctct ttggctagcc tgggttactg
    12481 accttgttaa tctcaagggc tctaatgcgt caacctatca gcatttgatg gagactgttg
    12541 ttccggctcg ttttaaggtt gggcaaatga ttggtgcaac aggaacgctt atgggggttg
    12601 ccctagcaat gtaccgtaat gttgatgcgg acaaaaagca taaatacaaa atgatgttta
    12661 tctcagcagc ggcagcggta tttttgacag gggtcactga gccactggaa tacatgttta
    12721 tgtttgctgc gatgccatta tatcttgtct atgcccttgt tcaaggagct tcctttgcaa
    12781 tggctgattt ggtcaacctt cgtgtgcatt cctttggtaa tatcgagcta ttgacccgaa
    12841 cgcctatggc gattaaggct gggcttggta tggatttgat taattttgtc tgggtgtcta
    12901 ttctgtttgc tgtgatcatg tatgtcattg ctgactttat gattaaaaaa atgaagctag
    12961 caacagcagg tcgcctaggg aattacgatg ctgatatact agaaaacgat gatacaaagc
    13021 ctttgtcaca gcagtctatt gatggtcagt cacaggtcgt ccaaatcatt aatctcctgg
    13081 gtggacgtga gaatattgct gatgtagatg cttgtatgac tcgcttgcgt gtaacagtca
    13141 atgacccaag caaggttggc agtgaggagc attggaagca ggcgggtgct atggggctaa
    13201 tcatcaaggg cagtggtatt caggctgtct atgggccaaa ggctgatatt ttaaaatcag
    13261 atatccaaga cctgctagac tctggtgcag tcattccaga gccgaagcct gctcagcctg
    13321 ctgcctcatc atcacagcag acggacttta aaaacctaac agaggctgtt ttggcagtag
    13381 cagatggaga agtcttgcca atcacagcag tttctgatca ggtctttgca gctaaaatga
    13441 tgggagatgg ctttgctgtt gagccggcaa atggcgctat ctatgcgccg gtaacaggtc
    13501 tggtaaccca tgtctttcca accaaacatg cctttggctt gctgacagat agcggcctag
    13561 aggtgctggt tcacgttggt cttgataccg ttgacttgaa tggtgagccc ttcactgtca
    13621 aggttagtga gggtcagcgc gtatcggcag gagatctctt ggctgaggct gacctaactg
    13681 cgattacagc agcaggacgc aagacaacgg ttgttgtcgc ctttaccaat actacaagca
    13741 tcaaagctgt taaccttgtt gcgactggtc aacaaaaagc gaagaccctc gttgcacagg
    13801 tagagcttta agaataacca aagagagtgg tagatagcag tatgtcagac ctgcaggctg
    13861 ccacttctct tgtcgtatag gagaagatat gaccaagctc ttaaccctta acacacattc
    13921 ttggatggaa gccaatgcct taaaaaagct gttcgacttg gcagagcata ttttggctca
    13981 gaactatgac gtgatttgcc tacaagaaat caatcagctg attgacagcg aagcagcagt
    14041 gccattatca ggctaccagc caattgcagg gacacctgcc attcatcagg ataactttgc
    14101 cctcttgctt gtcaattact taaaaaaacg tggccaaagc tactactggt cgtgggccta
    14161 caatcatatt ggctatgata tttaccatga gggtgttgcg atcttatcca agcagccgat
    14221 ccaagcctca gacattttag tctcagcggt ggctgacgag tatgattacc acaccagacg
    14281 ggctttactg gccaaaacaa ccattgatgg cagggaggca gcagttgtga gcctgcattt
    14341 gtcttggttt gatcagggct ttgtcggaga atggcagcga ttagaggcag ccctgcagca
    14401 gctagcctgt cctgtgctat tgctgggaga ttttaacaat ccaagtggcc aagagggcta
    14461 tgagatgatt ctaaaaagcc ccttagacct tcaggatagt catcaggctg cagactacgt
    14521 ctttggagac catagtattg ttgctgctat tgatggctgg gaggataaca aagaggcctt
    14581 taaggtcgac catgtcttta ccagtaaggt ctttaccatt aacagctcaa aggtgacctt
    14641 tgatggtggt gaagcaccgg ttgtcagcga ccattatggc ctagaggttg acctcagctg
    14701 gaagctgtaa caaaaaaagc cagcaggact tgatagactg ctgacactgt aagaaacaga
    14761 tggttatctt agctcttaga agtaagctta tcgcaaggct tctaagagct tttttgcatt
    14821 tatatttcat gagcatatga gaaagttgca gacaaatgct ggacacataa tcagactgtg
    14881 ggctagttac atcgtctgct ctgatttgtg tcagatagtg atgatctgtg ctgccttgtg
    14941 attggccaga tatttacctc atatcaatag cagaaagtca agtctccctc agcctatctc
    15001 ctagcttacg attgctgatc atcagtcagt ctagctacaa ttacctgtgc caagcgctca
    15061 atatcagcac tggtcccgcg tagttcgaaa tctcccagca ttggaaagcc aaagcgctta
    15121 gcatactgct tggctgttag acaatactgg tgattgaagt ttttgttgcc agagccgata
    15181 atccctaaac aacgcttggc attatcatgc gccgcgataa agtctcccag cggattggtc
    15241 aagatttcaa cctcccctga gtcaatcccg tttcctcctt caagataggt cggcaaaata
    15301 gcaacaaagc tctccttgac tggaaaggtt tcgtgatgaa gctccttgat attgattgct
    15361 ttagtctgta tgtggtgctt ttctgccagg tattgcgaca agcgcctaac aaagctcagg
    15421 gtattgccgc taagactgat aaaaacaagg gtcaagtctg tcataaaaga ctcctttagc
    15481 aagattagtt tcctaaccag cttagcacaa tacccctgaa tacacaactc atatgacaat
    15541 gctctgcacg acaaacgcgc gaaacagtca tttccgaatg atagtataga cttaagcaga
    15601 tacattcacc gttttttcta tagtaaaagc tatagaaaat aagatatctt cttgaaatag
    15661 ctaaacattg acatacagaa agctttgttt tcttgctaaa accctatcat gcgtctgccg
    15721 tgcaatgctc tgacagctag cccactagtc acatcacata aaaaaggctt ggtgacaagg
    15781 acggtaagtc caaatcatca agtcttttta tggagagagc ttagtgttag ctgttacccg
    15841 aatcaagagg cccttgctgc taatgcttgc gattttgata ggtctttggg ctttctccgg
    15901 tatgcttttt gaaaaattta gaaaaatgtg agggatcagt gaagcccaac acgtctgaaa
    15961 tgtgattaat ggcataagca gagcgcagca atgtcttagc ctcttcaatt ttcatgtttg
    16021 aggtgtattg gtagatggtc aagcctgtat cacgcttaaa gatctgtctc agcttggact
    16081 cgctcatgtt aaaatgctgt gccagctcag cggttgtgac actcttatgc aggttgacac
    16141 tgatatattg gataatggca ttaaccgtag gagagacatg tttccagcgg ttgtcccgca
    16201 gctcactcac cttttgggtg taaaagacca gtgaggcatc acgaattttg agcacatctg
    16261 gcattgaggt tgccagctcg ctgtctctca tgaactcctc tcgtgaatgg taggcatcag
    16321 caatatccat accagattga atggcaatct gggctagtcg atcaaaggca atgatagaat
    16381 aatttttttc agagcgcagc gtatcaccac tcaccacagg gataaaggta tttcgtagac
    16441 tgaagatgat ttccttgagc ttgtgcacat caccctcttg aacaatgcta gataaatttt
    16501 tctcataatt gtagagacaa accttagatt cctgcttctt gacaaacata ttggcctttt
    16561 gcacctcgat attgtcggaa aaatccctaa tatagtgacg taaaggaggt gataacaaat
    16621 cctctatctt gccggaaaag aagtaatgga ccacaatcaa gaggtcacga atagcattca
    16681 aaggataaac aggtaaatgc tttagcgctt ggtaaagaat ctcttcttct tccttagtca
    16741 aatccttatc agcaacggcc accttaaaaa aggtcttatc caaaacatta cagcgccaag
    16801 ggccaattaa aatataatga tcctgataac ggtatattaa aaaaagctca ttatagcttc
    16861 cctgaaagaa aagattggtt gcctgttcct tgtccatttg cctaagcact gcttgaaaac
    16921 gataataaaa ttcaaaggta tcatcattcc aaaagctttc tgtcacctga tggtccttat
    16981 caaatactgt aattgataac ttcaaacagc cctgtagaga ttttactaac gacatagtat
    17041 ccatgctaag cgtcaccccc ttcataatcc tcacggtatc ttattctatc ttaaaattta
    17101 agaaaagcaa ggatatgcac ttataatgaa aaaatagaca taaaaaacaa taatatacat
    17161 tcttgcttat taaataaaaa tgacaatgta ctgcataaag aagttcctgt cattaaaata
    17221 aaagtgccat gaggttataa tagtatggta aaacaaaaaa gtgtgcccat aacgggtaga
    17281 gaggaattga catatgtttt tgagaaataa caagcaaaaa tttagcatca gaaaactaag
    17341 tgccggtgca gcatcagtat tagttgcaac aagtgtgttg ggagggacaa ctgtaaaagc
    17401 gaactctgag gttagtcgta cggcgactcc aagattatcg cgtgatttaa aaaatagatt
    17461 aaacgatata gccataagta gagatgcctc atcagcccaa aaagttcgaa atcttctaaa
    17521 aggcgcctct gttggggatt tacaggcatt attgagaggt cttgattcag caagggctgc
    17581 gtatggtaaa gatgattatt acaatttatt gatgcacctt tcatcgatgt taaatgataa
    17641 acctgatggg gatagaagac aattaagttt ggcttcatta cttgtagatg aaattgaaaa
    17701 gcggattgct gatggagata gttatgcaaa acttcttgag gctaaacttg cagctattaa
    17761 atctcaacaa gaaatgctta gagaaagaga ttcccaactt cgaaatctag agaaggaaaa
    17821 agaacaagaa ctacaaaaag ctaaagatga gcgtcaagct cttaccgaat cattcaacaa
    17881 aactttatca agatcaacaa aagagtataa taaactaaaa acagaacttg caaaagaaaa
    17941 agaaaaagca gctaagatga ctaaggaatt agcagataag ctaagcaatg ctgaagcaag
    18001 tcgtgataaa gcctttgcag tatcaaaaga tttagcagat aaactaagta gtgctgaagc
    18061 aagtcgtgat aaagcttttg cagtatcaaa agatttagca gataaattgg cagctaaaac
    18121 agcagaagct gaaaagttaa tggaaaacgt tggtagtcta gaccgcttgg tagagtctgc
    18181 aaaacgtgaa atggctcaaa aattagcaga aattgatcaa ttaactgctg ataaggctaa
    18241 ggctgatgca gagcttgcag ctgcaaatga caccattgca tcacttcaaa cagagctaga
    18301 aaaagctaag acagagcttg ctgtttcaga gcgtttgatt gaatcaggca aacgtgaaat
    18361 tgctgagcta caaaaacaaa aagatgcttc tgataaggct ttagtagaat cacaagctaa
    18421 tgtagcagag cttgaaaaac aaaaagcagc atcagatgct aaggtagcag agcttgaaaa
    18481 agaagttgaa gctgctaaag ctgaggttgc agatcttaaa gcacaattag ctaagaaaga
    18541 agaagagctt gaagccgtta agaaggaaaa agaagcgctt gaagctaaga ttgaagagct
    18601 caaaaaagct catgctgagg aactttcaaa acttaaagaa atgcttgaga agaaagacca
    18661 tgcaaatgca gatcttcaag cagaaatcaa tcgcttgaag caagagctag ctgacaggat
    18721 taagtcattg tcacaaggtg gtcgtgcttc acaaacaaac ccaggcacta caactgctaa
    18781 agcaggtcaa ttgccatcta ctggtgagtc tgctaaccca ttcttcacta ttgcagctct
    18841 tactgtcatc gctggtgctg gtatggctgt ggtgtctcct aaacgcaaag aaaactaagc
    18901 tatttcctct ttccccaatg gacaatagcc gaaataatag agcgactatc gttctaacac
    18961 aaaagcaaca gtctcctgtc tgttgctttt tgtgatatta gggctcatca gtctaggcta
    19021 atggttttct gcgctttatc tgcagctttg aggattcctt cttttgcttt tacagtgaaa
    19081 gtgttaaaat aggaaaaaca actagtaatt gaggaagtaa atggttaaag aaatcaattt
    19141 atcaggagag gaagtagttg cccttgctgc caagtacatg acagacggtg acgtcgagct
    19201 tgtgcaaaag gcgcttgatt atgcgacagc tgctcatttt taccaggtta gaaagtcggg
    19261 ggagccttat attgtgcacc ctattcaggt agcagcaatc ctagcagacc tgcatttgga
    19321 cgctgtgaca gttgtctgtg gctttttgca tgatgtggta gaggatactg atattactct
    19381 agaggacatt gagtttgact ttggtaagga cgttcgtgac attgttgatg gggtcacaaa
    19441 gcttggtaag gtagaataca agtctcacga ggagcagctg gctgaaaacc accgcaaaat
    19501 gctcatggcc atgtcaaagg acattcgtgt gattttggtc aagctagccg accgactgca
    19561 caatatgcgc accctcaagc acctccgtaa ggacaagcag gagcggattt ctcgtgaaac
    19621 catggaaatc tatgccccgc tagcccatcg cttggggatc agtcggatca agtgggagct
    19681 ggaggatcta gcttttcgct acctcaatga gatcgaattc tacaaaatct ctcatatgat
    19741 gagagaaaag cggcgggagc gcgaagcttt ggttgatgat attgtcacta agattaaagc
    19801 ctacaccacc gatcaagggc tttatggtga tgtctatggc cgtcctaagc acatctactc
    19861 ggtttaccgg aaaatgcgtg acaagaaaaa gcgctttgat cagatatttg acttgattgc
    19921 gatccgttgt gtcatggaga cacaaagtga tgtttacgcg atggtcggct atattcatga
    19981 gctctggcgt cccatgcctg gccgcttcaa ggactacatt gcagcgccta agaccaatgg
    20041 ctatcagtcg attcacacga ctgtttacgg gccaaaagga ccgattgaaa ttcagattcg
    20101 gaccaaggaa atgcatcagg tcgctgagta tggggtagca gcccactggg cctacaaaaa
    20161 aggtattcgt ggcaaggtca atcaagtcga gcaaaaggtt ggtatgaatt ggattaagga
    20221 gcttgtcgag cttcaggctg cctcaaatgg cgatgctaag ggctttgttg actcggtgaa
    20281 ggaggacatc ttttcagagc gtatctatgt gttcacaccg acaggagcag tgcaggaatt
    20341 gcccaaggat tcaggcccta tagactttgc ctatgccgtt cacactcagg ttggtgaaaa
    20401 ggcgacagga gccaaggtca atggccgcat ggtgcccttg acagccaagt taaaaaccgg
    20461 tgatgtggtg gaaattgtca ccaatccgaa ttcctttggt cctagtcgtg actggattaa
    20521 gctcgtcaag accaataagg ctcgtaacaa gattcgccaa ttctttaaaa atcaggacaa
    20581 ggagctgtct atcaataaag gacgtgagct tctggttagt tattttcaag agcagggcta
    20641 tgttgccaac aagtaccttg agcgtaagcg tattgaggag attttaccaa aggtcagtgt
    20701 taaaagcgag gagtctctct atgccgctgt tggctttggc gatattagcc cagtcagtgt
    20761 ctttaataaa ttaaccgaaa gagaaaggcg tgaggaggag cgtgccaagg ctaaggctga
    20821 agctgaggag ctggttaagg gcggtgaggt caagcatgaa aacaaagaga ttctcaaggt
    20881 ccgcagtgaa aatggcgtga ttatccaagg ggcgtctggg cttctcatgc gtatcgccaa
    20941 atgctgcaat cccgtaccag gagatgtgat tgaaggctat attaccaagg gacgaggcat
    21001 tgctattcac cgcgcagact gtaataacat caagagtcag gacggctatc aggagcgtct
    21061 cattgaggtt gagtgggatt tggagcattc tagcaaggat taccaagctg agattgatat
    21121 ttatggttta aatcgtatcg gcctgctcaa tgatgtcctg caaatcctat ctaacgccac
    21181 caagagcatt tcaactgtca atgcccagcc gaccaaggac atgaagtttg ccaatattca
    21241 tgtgagcttt ggcattccta atctggctca gctgacagct gttgttgaaa aggtcaaggc
    21301 ggttccagat gtttacagcg tcaaacgaac caacggataa aaaggagacc aaccatgaaa
    21361 attgtgattc agcgcgtcaa ggaagcctca gtgtcgattg atgggaaaat agctggcgct
    21421 attgatcaag ggctgctgct gcttgttggc ataggtccag atgatcaggc agaggatata
    21481 gactatgcag tgcgtaaaat cagtcatatg cggatttttt cagaccccga gggcaagatg
    21541 aaccgatcca ttcaggacat tgagggcagt gtcttgtcta tctcgcagtt tacgctatat
    21601 gctgacacca aaaagggcaa ccgacctgcc ttcaccgggg ctgctaagcc tgacagggcc
    21661 agccagcttt ataacagctt caacgctcag ctagagcagc ttgtaccggt tcagcgaggg
    21721 gtctttggtg cggacatgca ggttagtctg atcaatgatg gcccagttac gattatccta
    21781 gatacgaagt atcgataact gcctagcgat cgatcgtttg cttaggagag tcatataaag
    21841 gaaaaacaaa aagacgagtg gtatgagaag cactcgtctt tgtcgtttat gctgctgtgt
    21901 tgaagctagc tagggctact agtcttattt ttgcaggtct ttgtagactg cgatgaattc
    21961 tgtctcagaa attggggtta agctgccagt gaattggtaa gaagtaccat ttttagcttg
    22021 gaaagtatta ggtaaacctt taaggtattt gtcgatagtc tcagtggtaa ttgcttcgtg
    22081 tgttttaaag gtgtattcgt taatcagctg ctgctgtttg tcctgttggt aaatagtaac
    22141 tgaacgatag gttgtgctat agtcatcgtt aatatcctta gaaataaaat aggtttctac
    22201 aacagaatct gaatgtgtcg catagctaat gggattgttg acgtcatact ttgaattata
    22261 tacttgagct atcctgttag aatctatgat atagttaaag tcctcatcgc gatcagcatg
    22321 gtagaccatg cgttcactag ctccactgta aatctcaccg ttatggcttt gatgagttat
    22381 atcaggatcc tgcgtgactg ttgtactgat tcgcttgacg agctgatacc cgtctttgaa
    22441 agcctgagtg gtttcaaaag cctttttagc agcttcaaag agctcctcag aagagaccct
    22501 gctgccatag tatcttaacc cggtaagtcc ttctttacca aggctgtcag ttacatcaac
    22561 attaacaagc tgcccattgt cttttttgag gaatttaacg tgctgtgtca cagctacggc
    22621 atctgaatct tggattgggt ttcctgcctt atctgttacc ttaatgtcct tgagagctac
    22681 cttgctaact ttttccacaa ggacctgacc cgtcaagatg tatgtttggt ctttttgatg
    22741 atactgtcct ttgattggtg tcgtaaaatg gtctgtgcta agtatttcag ctgtagaagc
    22801 ttttgttaat ttggcatttt tcaaactaat gaccttaaag ctttctgctg aaggatctat
    22861 gacgtcttga actagcttta tcatctcatt tgtggtgtag gttttgccat attctagtct
    22921 aatatcctga taatgtggag atacgatggt gtgattagtg ttatctactc cagtgatatt
    22981 gaccatgagg tacagtcctg tggtttcttg atagtctttt gaatggattg gcttagtggt
    23041 gtcctcgtat ttatagtgat ttgctaccct actagagctt gaccatgccc acccaacttt
    23101 gtaatggttt gctttaacgg caggtgctcc caaggtcatg gtgaatagtc caatgactac
    23161 agttcctatt tctaaaggtg ttttcccaag gtgatacagt ctttttgaag tcaacatatt
    23221 tcaaacctcc ctaaatcctg tcagtctcta tagttataaa aatacagaga atcgttagaa
    23281 gaattaatgt ttcatgccgg caagatgagt gtaacaaaag attggtgccg atacaagaag
    23341 atggagatta gagcatctgg tttcaatgag agttacataa tagcagaagg ttttttcact
    23401 atgagagcta atcgtcttaa aatggtataa tagcaagtga ataggctatc taactggttt
    23461 aacagccatt tttagagaag cttaatagta ttgctgataa gtgactcgta tctccatatt
    23521 gcttttcaaa ggctatgtta gctatgataa gcgtgaccag gctatcggaa aatccagtgt
    23581 tcttaaaggc tttgaagctc tggctttgaa ccttagctct ggtgtttcta tgaaaatgac
    23641 ttgggccttg taccagataa gaatgaagtc aaattgaggt tttttgacaa aatgtttgag
    23701 taaatacaag ttcatagaag tctaatgtat aaaaatacaa ttgtatcgcc ataatctgaa
    23761 tgaccaaacc attaaaaaaa taaaattttt aaacattttg gaaaacgctt tcaaaactaa
    23821 aaagaactgt cctatagtca ttgcttagca ttaaagcaag gtgtgaaatg ttatcatatg
    23881 gagaaatagg ctgtcttgtg ctgtatctgt gccaaaaaag aatgcttgtt tttgtgatat
    23941 aatgtgacta agaaacctga aaggaatgct tatggcatta aaagactatt ttcctgatat
    24001 gcaagagggt gcatttcctc tggctgacca agattggatt agcgttgagg ttggggagca
    24061 gtacctccat ttccccaaat ccagcttgtc agagcgagag cagcttttgc ttggtttggg
    24121 gcggcagcgc aaagagccgt ccaaggatca gaaatctcct tggtatcatt atttgattct
    24181 gggccaaggg gagcagccgg aggagtttca gggttgccag ttcatctata tcaaccatca
    24241 atgtccttta gcaggtgatt tgattgagct tctaaagggg atcatagagg gagttgaggc
    24301 tgttttgccc attagccaga ccaggacagc ttttttggtc tgtcaccata gccgttcaga
    24361 cctttttcag ctcttagcaa atttattgcc cacgattgag agcgattttg gtttggcctt
    24421 gatgattttt atcggtaatg gctggtatca ggtgtcagga aatgccttga gagactattt
    24481 taaggaagaa aatgctgtgt ttacagctta tcttgctgag cactctgcca gtcgcttgct
    24541 gaccttttca gaggtcatgc tctggtcact cttagcaaac agtggtttgc cagccttgtc
    24601 aaagcatttt agtcagctgc ttttagccaa taaagaggtc atggatctgg tgctcgccat
    24661 gtggcaggag catggcaacc tggtacagac agcccagcgc ttgtatattc atcgcaattc
    24721 gctgcaatat aagctggata agtttgctca gcagtcaggt ctctatttaa agcagctaga
    24781 tgacttggcc tttgcttatc tatttatact gaagcattag atttgtgcag ggtgcccaaa
    24841 gacatttggg cgttttgtct atatgatgaa aacgctatct ttgctataat aaaagcatca
    24901 aataaaaagt gtcagggttg ctagcattgc agtcagctag cagcctatct gacccattag
    24961 gagtaacgca tggttgaatt aaacttaaag cacatctata agaaataccc aaataccaca
    25021 cactatgctg ttgaggattt cgatttagac attaaggata aggaatttat cgtttttgta
    25081 gggccttcag gctgtggtaa gtcaacaacg cttcgtatga ttgctgggct tgaggatatt
    25141 tcagagggtg aattgaaaat tgacggtgag gttgtgaatg acaaatcacc aaaggaccgc
    25201 gatatcgcga tggttttcca aaactatgcc ctttacccgc atatgaccgt ttatgacaac
    25261 atggcctttg gtctcaagct acgtaaatac aaaaaagatg atattgatcg tcgtgtcaag
    25321 gaagcagcag aaatccttgg cttgacagaa tttttagaac gtaagccagc agacctttct
    25381 ggtggtcagc gtcagcgtgt ggctatggga cgtgctatcg tgcgtgatgc caaggtattc
    25441 ttgatggacg agcctttgtc aaacctagac gctaagctgc gggtgtcaat gcgtgctgaa
    25501 attgcgaaaa ttcaccgccg tatcggctca acaacaatct acgtaacgca cgaccagacc
    25561 gaagcgatga ccttggcaga tcgtatcgtt atcatgagtg ccactaaaaa ccctcaaggc
    25621 aacggtacaa tcggaaagat tgagcaggtt ggctcaccac aggagctcta taacctaccg
    25681 gccaataaat ttgttgcagg ctttattgga agccctgcga tgaacttctt tgaggtggtt
    25741 gtcaaggacg gtcagatcat cagtgaggac gggcttgata ttgctattcc agaaggtcag
    25801 gctaaaatgc ttgaagcagc tggctataag ggcaagaagg ttatttttgg tatccgtcca
    25861 gaagatattt caagcaacca aatcgtgcat gacacctatc caaatgccaa tgtcacagca
    25921 gaggtcttgg tttctgagct gcttggatct gaaaccatgc tttatgttaa gcttggtcaa
    25981 acagagtttg cttcacgagt tgatgcgcgt gacttccaca atccaggtga aaaggttagc
    26041 ttgaccttca atgttgctaa ggggcatttc tttgatctag aaacagagca agctattcgc
    26101 taataacacc tcctagaata aaatcctcat cttgcttgag gattttttaa caaaagaaaa
    26161 tgcaagcgat tgcgctatca aaaagaaaaa gggatttatc ataaagacaa cagatgttct
    26221 gtagtgctag gcgatcataa tgatggcacg aaatagcagg agactgttta gtaataagga
    26281 gatatgatgg aaaaacactg gtggcataaa gcgacaattt atcaaattta cccaaggtcc
    26341 ttcatggata caagtgggaa tggtattggt gatttaaaag gaatcacagg taagctggat
    26401 tatctacagg agctagggat cacagctatt tggctgtctc cagtttatca atcaccaatg
    26461 gacgataacg gctatgatat ttcagactat caggccattg cagctatttt tggtgatatg
    26521 gctgatatgg acgagctgct tgatgaggcc aagcagcggg ggatcaaaat catcatggat
    26581 ttggttgtca atcacacctc tgatgagcac gcttggtttg tggaggcaag agaaaatcct
    26641 gacagtccta aacgagatta ttacatttgg cgtgatcagc ctaataatct catgtcgatc
    26701 ttttctggct ctgcttggga atatgatgat gcctctgggc agtattatct gcacatattc
    26761 agtaaaaaac agcccgactt gaattgggaa aatgctgaat tgcgtcaaag catttatgac
    26821 atgatgaatt tctggattga taaggggata ggtggctttc gcatggacgt cattgacctg
    26881 attggtaaga ttccggattc tgaaattaca ggcaatggcc caaggctgca tgaatacctc
    26941 aaggagatga accaggcaag ctttgggaat catgacctga tgactgttgg tgaaacatgg
    27001 ggcgctacac cggaaattgc tcgtcagtat tcacgtcctg aaaataagga gctgtcaatg
    27061 gtctttcaat ttgaacatat cggcttgcag cataagccaa atgcttctaa atgggattac
    27121 gcagctgagt tgaatgttcc ggctctcaag gagattttta gcaagtggca gacagagcta
    27181 aagctaggtg aaggctggaa ctcccttttt tggaacaatc atgacttgcc tcgtgtcgtc
    27241 tccatttggg gaaatgatac agtatataga gagaagtctg ccaaggcaat ggctattttg
    27301 ctgcatttaa tgcgtgggac accttatatt tatcagggtg aagagattgg catgaccaat
    27361 tacccctttg agcgcttgag tgatgtgaat gatattgaat cactgaatta tgccaaggag
    27421 gctatggcta atggcatgtc agaggaggct gttcttgatt gtatttgtag ggtgggtcga
    27481 gacaatgcaa gaacaccaat gcaatggagc agtcaaaaga acgccggctt ttcaactgct
    27541 gatcagacct ggctgcctgt caacccaaat catcaagaga ttaatgtggc tagtgctcta
    27601 gctgatcctg attctgtttt ttacacctat caaaagctta ttcagctgcg tcagacacag
    27661 gattggctgg tggaggcaga ttatcagctg ctggaaacat cagataaggt ttttgcctat
    27721 aagcgtcagc ttggtagaga gacttacctt gttgttgtca atctgtctaa tcaagagcag
    27781 ttttttgaag aaagtcttca taaggcccaa gtgattatca gcaataccga tgtgcaggca
    27841 gtcgtagaaa gtcaacagct ggagccttgg gacgcctttt gtgttaagct tgatgagacc
    27901 ttgtagccta gctgcttgct gtgcctcagc tcaataatcg tagcgattct ttgagaattt
    27961 tgacaaattg ctgtatgatt agtagaagaa ttagatacaa aagaggaggc tgagatgacc
    28021 gttgaagaaa ccatgacctt tgcaaaaagc attgcagcat ttagataggt agagattagt
    28081 gaggtagtca ctaggctagc agcaggtgag gacatcaccg tctttttagg cagagcgacc
    28141 tgtccttatt gtcgtcgctt tgcacccaag ctagcaagcg tagcaaggca ggagcataag
    28201 gatattttct ttgtagatag tgaagactca acagagcttg cagacctgca ggcctttcgt
    28261 gagcgctatg ggcttgctac tgtgcctgcc ctgctcatta gtcgtcatca ggaggtcaag
    28321 gcagtctgtg attctagctt gactgaggaa gccattttgg ctttcctaga gcagtgacag
    28381 acagctaatt atctggtgca agtaatagaa atgtaatcag tcatgtcttg ctatgtgagt
    28441 ccaaatctgc tatagtagga catgactttt agacgaaata aggagatatt atgggcttac
    28501 caacaatttt aatgtttgtt gtcatgattg gtttaatttg gtttatgcag cgtcagcaaa
    28561 aaaagcaggc gcaggagcgc caaaatcagc ttaatgcgat tgaaaaaggc gatgagattg
    28621 tgacgattgg tggcatgttt gcagtggtcg atgaggttga tttagcagca aagcgaattg
    28681 tcttagatgt tgatggtgtc tatctgccat ttgagctatc agcgatcaag cgcgtggtcg
    28741 aaaaaggaag tgcagtgaca tcagctgatg tggatacgac agagactgca gttgatgaca
    28801 cagcggttga ggcttcagac gaagctgaat cagctattga gacaaattaa gaaaatgagg
    28861 tctgaagcat tagtgtttca gactttttta ggtgatgata gcaggtagcc agacagagct
    28921 gtcatgtgct atggaaatat cgtctacaac gagaaaaagc gagccaaacc gcatgaaata
    28981 tggtaaaata tgaggtaagt atgcttgtga ataaggaaaa aacatgtttg gattaaaagc
    29041 gaagtcaaaa aaaatcgttt tggataggat tccaaagcac attgggatca tcatggatgg
    29101 taatggacgc tgggcgaaaa aacgcttaaa gccgcgtgtc tttggacata aggcgggtat
    29161 ggacgctttg caggaggtaa cgattgcagc ttcagattta ggggttaagg tgttaacagt
    29221 ctatgccttt tcgacagaaa attggtcaag accacaagat gaggtgagct tcattatgaa
    29281 cctgcctgtt gagttttttg ataagtatgt gcctgagctg cacaaaaata atgtcaaggt
    29341 gcagatgatc ggtgagacca accgcctacc taaggataca ctaaaggcct tggaagcagc
    29401 tattgctaag acaaggcaaa atactggctt gattctaaac tttgctctta attatggggg
    29461 tcgcgcggaa atcaccaatg ctgtcggtct cattgctcaa gatgtcctag acgccaagct
    29521 gaaccctggt gacattaccg aggatttgat tgccaactat ttgatgacgg atcatttgcc
    29581 ctatctctat cgcgatcctg accttattat cagaacgagc ggtgaattgc gcttgagtaa
    29641 ttttatgcct tggcaatcag cctatagtga gctttacttt acgccggtgc tgtggcctga
    29701 ttttaaaaga gctgaactac taaaggccat agaggattat aaccatcgtc atcgccgttt
    29761 cggtgctatt taaggagaga gtatgagaga acgtttcatt tggggtggtg ttgcagctgc
    29821 tgttttccta ccctttttac tcattggcag cttacccttt caattgtttg taggtgtgct
    29881 tgccatgatt ggtgtatcag agctgttaag aatgaagagg cttgaggtct tttcctttga
    29941 gggtgttttt gccatgctag cagctttcgt tttgacagtg ccgttggatc attacctgac
    30001 ctttttgccg atggacgcta gttttgcttg ttacgggctg ttggtgtttt tccttttagc
    30061 aggaatagtg attagcagcg attcttatgg ctttgaggat gctagctttc cgattgcagc
    30121 tagcttatat gttggtattg gctttcataa tctggttaat gcgcgaatga cagggataga
    30181 caaggttttt ctggctcttt ttattgtctg ggcgactgat attggagctt acttgattgg
    30241 gcgccgattt ggtaagcgaa agctcctgcc aaaaatatca cccaacaaaa caattgaggg
    30301 cagccttggt ggtatagtca gtgcggtgct tgtttccttt gtgtttatgc tctttgataa
    30361 ggctgtttat gctcctcatc attttggaac aatgttgatt ttggtggctc ttttttctat
    30421 ttttgctcag tttggagatt tggttgaaag tgctgtcaaa agacatttcg gagttaagga
    30481 ctcaggcaaa ttgattccag gccatggtgg tattttagat cgttttgatt cgatgatctt
    30541 tgtttttccc attatgcatc tatttgggtt attttaaagc tcattatcaa tagactgaaa
    30601 ggaaatctat gttaggaata attaccttta ttattatttt tggtattctt gtgcttgtcc
    30661 atgagtttgg ccatttctat tttgctaaac gatctggtat tttagtcaga gagtttgcta
    30721 ttggcatggg accaaaactc ttttcgcatg ttgatcagca aggaacgctt tacacgatcc
    30781 ggctattacc gcttggtggc tatgtgcgaa tggcaggctg gggtgatgac acaactgaga
    30841 taaaaacagg aacgcctgct agcttaacgc ttaatgatca gggcttggtc aagcggatta
    30901 acctgtctca gagcaagctt gatccgacta gcctgcctat gaatgtgact gcttatgact
    30961 tagaagataa gttgacgatt acagggctgg ttcttgatga gatcaagacc tattcggtag
    31021 accatgacgc gaccattgtc gaggaggacg gtacagagat ccggattgcg ccgcttgatg
    31081 ttcagtatca aaacgcaagc attggcggtc gtttgatcac caattttgca ggacctatga
    31141 ataattttat tctaggtatt gttgtcttta ttttgtttgc ctttgttcaa ggtggtgtgg
    31201 ctgattatca tagcaaccat attcgtgtgg tggaaaatgg cgcagcagcc aaggctggta
    31261 ttagagacaa tgatcagatt ttagagatta atcatcaaaa gattaatgac tggtatgagt
    31321 tgacgcaggc cgttactgat tcagcagcag atgttaaggc taagggcaag ctagagatta
    31381 cctatcagac aggtgatcag gttaagacta tagcactgaa gcctgaaaaa aaaggcgatc
    31441 agtaccttat tggtgtccag tacccactaa aaacaagtct gacagacaag ctaataggtg
    31501 gctttgagat ggctggtaat ggtgctctag tgattgtcac tgctctaaag agtttgatta
    31561 cctcctttag cctagataaa ttaggtgggc cagttgccat gtatcagatg tccaatcagg
    31621 cagcaaagaa tggtttagag tctgtcttgt ccttgatggc aatgctctct atcaatttag
    31681 ggatttttaa tttgattccg attcccgcac tagatggtgg taagatcctg atgaatgtga
    31741 ttgaagcact tcgtcgtaag ccattaaagc aagagacaga gacttatatt acccttgcag
    31801 gtgttgcgat tatggtggta ctcatgattg cagtgacctg gaacgatatt atgcgagcct
    31861 ttttccaagg ctgatggtct ctctcattta aaggagagcc taaaaggctt aatgtaacag
    31921 aaataacaag agatatagtg tcattattgt ggttctaaga ccttgcaaat gcagcaaaag
    31981 cttagccaat atagctcatt ttgtctcttt tttagaaatg aattctcaac gaaaggaaag
    32041 agagctgttg accaagctgg gctaaggcct acagctgaaa tcaaaatgct agacctgcta
    32101 ttagtctaag ggcgttttga gctgctctct atagcttatt ttaatgaaac aaagtaaaat
    32161 gcttatccca accctgcgcg aaatgccaag tgacgctcag gtaatcagtc atgccctcat
    32221 ggtgcgtgcg ggctatgtcc gtcaggtatc tgccggtatt tatgcctatt tgccattagc
    32281 tcatcgtaca attgaaaaat tcaagacgat tatgcggcag gaatttgaca aaattggtgc
    32341 tgttgaaatg ctagcacctg cccttttaac agctgacctc tggcgtgaat caggccgcta
    32401 tgagacttac ggtgaggacc tttacaagct aaaaaaccgc gacaaatcag actttatctt
    32461 aggtcctacc catgaagaaa cctttactac actggtgcgt gatgcggtta aatcctataa
    32521 gcagctgccg ctcaatctgt atcagattca atccaaatat cgtgatgaaa agcgtcctcg
    32581 taatggcctg cttcgcacac gtgaatttat catgaaggac ggctatagct ttcatcaaag
    32641 ctatgatgat ttagatgtca cctatgacgc ctatcgtcag gcctatgagg ctatttttac
    32701 cagagcaggc ttggatttca aaggaattat cggtgatggt ggtgctatgg gtggtaagga
    32761 ttcgcaggaa tttatggcta tcacaccgga ccgtactaat ttagaccgct ggctggtctt
    32821 agacaagtct attccgtcat tggctgacat tccagaggag gtcttggaag agattaaggc
    32881 cgagctggct tcatggctgg tttcaggaga ggacaccatt gcttattcaa gtgaatcaag
    32941 ctatgctgct aaccttgaga tggcaaccag tgagtacaag tcctcatcaa aggtaacagc
    33001 cttagatgat ctcgtcgaga ttgagacacc aaattgtaaa accattgatg aagtggcggc
    33061 ctttcttgac gttgctgagc atcaggtcat taaaaccctg ctctttatgg tggaccatga
    33121 gcctgtgctt gctttattgg ttggaaatga ccagatcaat gctgtcaaat tgaaaaacca
    33181 cctcggtgca gacttcttag agccagctag cgaggaggag gcgcgtgcta tcctaggtgc
    33241 aggctttggt tcacttggtc cagttcattt gacagatggt atccgtattg tggctgatcg
    33301 taaggtccaa gaccttgcta atgctgtagc tggagccaat aaagatggtt atcacctgac
    33361 tggtgtcaat ccaaatcgtg atttccaagc agagtatgct gatattcgtg aggtaaaaga
    33421 gggagagacc tctccagata gacatggcgt gctgcagttt gccagaggta ttgaaatcgg
    33481 tcatatcttt aagctgggga cccgctattc tgatagcatg gcagctaata tccttgatga
    33541 gaatggcaga gcagttccga ttgtcatggg ctgctatggt attggggtta gtcgtatcct
    33601 atcagcagtc attgagcagc atgctcgtct ctttgtcagc aagacaccaa agggtgatta
    33661 tcgctatgct tgggggatta atttccctaa agagctagct ccgtttgatg tgcatttgat
    33721 taccgttaat gtcaaggatc aggaggcgca ggacctgaca gaaagagtag aggctagtct
    33781 gatggccaag ggctatgatg tcctcactga tgaccgcaat gagcgtgtcg gctctaagtt
    33841 ctctgatagt gatttgattg ggcttccgat tcgtgtgacg attggtaaaa aagcagctga
    33901 gggcattgtt gagatcaaaa tcaaagcaac aggtgacagc attgaggtgc acgctgatag
    33961 cttgattgaa actcttgaca ttctcacaaa ggacaactaa tgatatgagg tcaacgatgg
    34021 ttgatctctt tttgtatgct ataatgaaag catgacaatt gaggaattac agcagctggt
    34081 gctagcagat catgagctaa tgactattct aagcattata gagaccttgc ctttaaagga
    34141 ttgttggctg gcagcaggtg caattcggaa cgctatttgg aatcatttag cttatgggat
    34201 aggctttgat ccgctgacag atgtagatgt ggtctttttt gaccctgaga tctcttacga
    34261 agctgagcag ctgctagaag agcagcttaa gtgtgcttat cccatgtacc aatgggaggt
    34321 tcgcaatcaa gcctatatgg cagcacataa ccccaagacg cctccttatc gatctagtca
    34381 agacgctatc acaaagtatc cggagcgctg tacagcgatt gctgttagac ttgtaggagg
    34441 acagctagag gtttttgctc cctatggttt agcagacatt agtcactttg tctgtcggcc
    34501 aacaccgcat tttttagagg attcagagcg tatggactgc tataggcagc gcctagcaaa
    34561 gaaggactgg cacaagaaat ggccacagct gacctaccac gactgctaag tcagaggaaa
    34621 caaagcaggc taggagctcc gtacagccaa gcaattagtc cgctcccaga cccgttagct
    34681 acagctctca cctagtcaaa acaagcacat gaacagatca ttggcagata gccttgcctt
    34741 tgcagatatt gtcacaccct atttagctgt accatgtgtc ttatgatagg cgtgatagtg
    34801 ctgtcagaag cgccagctga gccagaaaaa gcgttaagcc tacagcaagg ggcttttaac
    34861 ctttggtatg ttgtcttgta ggagaggtcg aaaatgatca ctatttatga taaaatagac
    34921 cctaagaaaa tcaggagaaa gctatgtcag atttattcgg taaattgatg gaacaaattg
    34981 aaatgccact tgagataaga caatcaagtg ccttttcgtc tgctgatatt atcgaggtca
    35041 aggtgcattc agtgtctcgt ctgtgggaat ttcatttttc ctttgcagag gttctcccga
    35101 tagagagcta tcgagagctg tcagataggc ttgtgagaac ctttgaggca gcagatatta
    35161 aggtaacatt tgacatcaag gcagagacaa ttaattattc ggatcagctg ctgcaagcct
    35221 actatcaaga agcatttgag catgagccct gtaatggggc tagcttcaag tcatcttttt
    35281 ctagacttca ggtcaggtat gaccatcatc agctgatcat tatggcacct gactttgtga
    35341 ataatgatca ctttaggaaa aatcatttac ccaatctggc agctcagttt gagcgctttg
    35401 gctttgggag gctagcgatt gatatggtgt ctgatcagga gatgacagac catttgacaa
    35461 aggactttga gaccaaccgt caggctctgg tggaaaaggc tgtacaggat aatatcgcag
    35521 cacagcaatc attggaggcc atgcagccac cagctgagga ggcagcacca agcccaagcc
    35581 ttgactatag agagcgtatg gctcagcgcc aagcaagctt tgataaggcg gtcattacac
    35641 caatgattga ggtggataca gaagaaaatc gcattgtttt tgaaggaatg gtctttgatg
    35701 tggagcgcaa gacgacaaga acaggccgcc atatcatcaa cttcaagatg acagattaca
    35761 cctcctcctt tgccatgcaa aaatgggcca aagatgacga tgagctcaga aaatttgatc
    35821 tgattgcgaa gggagcttgg ctgcgcgttc agggaaatat cgaaaacaac cccttcacca
    35881 agagcctaac catgaatgtg cagcaggtta aggcgattgt tcaccatgag cgtaaggatc
    35941 tcatgccaga agggcaaaag cgtgttgaat ttcatgcaca cactaatatg tccacaatgg
    36001 acgctctacc gacggtagaa gacctgattg atacagcagc caggtgggga catcaggcag
    36061 tagcgattac tgaccacgct aatgttcaga gctttccgca tggctatcat agagcacgca
    36121 aggcaggaat caaggcaatc tttggcttag aggccaatat tgttgaggat aaggtaccta
    36181 tttccttcaa tcctgtcgct atggacctgc atgaagccac ctatgttgtc tttgacgtgg
    36241 agaccaccgg cctttctgcc atgaacaatg atttgattca gatcgcagct tccaaaatgt
    36301 tcaagggaaa tatcattgag cagtttgatg agtttatcaa tccaggccac cccttatctg
    36361 cttttacaac agaattgaca gggattacag ataatcattt ggtaggagct aagcctatac
    36421 agcaggtgtt agaggcattt caggcctttt gtcagggcac tatcctagtt gcccacaatg
    36481 ctagctttga cgtgggattt atgaatgcca actacgatcg gtatggttta gcaaaaatca
    36541 gccagccagt tattgacacc ctggagcttg ccagaaacct gtaccctgag tataagcggc
    36601 atggcttggg ccctttgact aagcgctttc aggttagcct tgagcaccat cacatggcca
    36661 attacgatgc tgaagcaaca gggcgtttgc tctttatctt cctaaaggaa gctagagaaa
    36721 agcatgggat tacaaacctg cttcagctca atacagactt agtggcagag gattcctata
    36781 agaaagcacg gatcaagcac gccacgatct atgttcaaaa tcagctaggt ctcaaaaaca
    36841 tgtttaagct ggttagcctt tcaaatgtga aatattttga aggtgtgcct agaattccaa
    36901 gaaccgtcct tgatcagcat cgtgaaggct tgctgcttgg gacagcctgc tcagacggcg
    36961 aggtctttga cgctgttttg acccaaggaa ttgacgctgc tgttgatctg gccaaatact
    37021 acgattttat cgaaatcatg ccgcctgcaa tttaccagcc cttggtagtc cgagagctaa
    37081 tcaaggatca agcaggagtt gagcagatta ttcgcgattt gattgaggtc ggccgcagag
    37141 ctgaaaagcc tgtcctagct actggaaacg tgcactacat tgagccagag gacgccatct
    37201 atcgtgacat tatcgttcgt agtctagggc aaggtgccct gattaaccgt actattggcc
    37261 gcggagaggc tgccaagcct gtcccgctac cagaggctca ttttagaaca accaatgaaa
    37321 tgcttgatga ttttgccttt ttaggtcagg acttggccta tgaggttgtg gtgcaaaata
    37381 cccaagccct tgctgatcga attgaaaagg tggaggttgt taaggatgat ctgtacaccc
    37441 catatattga taaggcagaa gaaaccgttg ctgagctgac ttatcaaaag gcctttgcta
    37501 tctatggcaa cccacttcca gatatcattg atctgcgcat tgaaaaggag ctaacgtcca
    37561 ttttgggaaa cggctttgcg gtgatttatc tagcctcaca aatgctggtt aatcgctcta
    37621 atgagcgtgg ttatctggta ggctcacgtg gctctgttgg ttcaagcttt gttgcgacca
    37681 tgattggcat cacagaggtc aatccaatgc cgcctcatta tgtctgccca agctgccagc
    37741 agtcagagtt tatcacagat ggctcggtcg gctctggcta tgatttgcca aacaaggcct
    37801 gtcctagatg tgggacgctg tacaaaaagg acggacagga tattcctttt gaaaccttcc
    37861 ttggctttga tggtgataag gttccagata ttgatttgaa cttctcagga gatgatcagc
    37921 ccaatgccca cttggacgtt cgtgatatct tcggggaaga atacgccttt cgtgcaggta
    37981 ctgttggtac tgtcgctgaa aaaacagcct atggctttgt caagggctat gagagagatt
    38041 atggcaagtt ttacccagat gcagaggttg atcgtctagc tgctggtgct gctggtgtta
    38101 agcggacgac tggtcagcac cctggtggga tcgttgttat ccctaactat atggacgttt
    38161 atgattttac acctgtgcag tttccggcag atgatgtgac agcctcatgg cagacgaccc
    38221 actttaattt ccatgatatt gatgaaaatg tcctaaagct cgatgtactc ggtcatgatg
    38281 atcccaccat gattcgtaag ctgcaggatt tatcaggtat tgatccgatt actattccag
    38341 cagatgatcc tgacgtgatg gcactttttt ctggaacaga ggtgctcgga gtgactcctg
    38401 aacaaattgg aacaccaaca ggtatgcttg ggatcccaga gtttggaacg aactttgttc
    38461 gtggcatggt gaatgagacc cacccaacga cctttgcaga attgctgcag ctatcaggtc
    38521 tatcgcatgg aacggacgtc tggctgggta atgctcagga tctgatcaaa gaaggcattg
    38581 ccaccctaaa aacagttatc ggttgtcgag atgacatcat ggtttacctc atgcatgctg
    38641 gtctagagcc taagatggcc tttaccatca tggagcgtgt gcgtaagggg ctctggctaa
    38701 agatttccga ggaggagcgc agctcctata tcaaggccat gcggcaaaac aacgtcccag
    38761 actggtacat cgaatcctgt ggtaaaatca agtacatgtt ccccaaggct cacgctgccg
    38821 cctatgtttt gatggcattg cgagtggctt atttcaaggt tcatcacccc atcatgtatt
    38881 actgtgctta tttctctatt cgtgccaagg cctttgagct caaaaccatg agtggtgggc
    38941 tagctgctgt caaggctcgc atggaggaca tcagcaacaa gcgcaagcgc aatgaagcct
    39001 caaacgttga aaatgacctg tttaccactt tagaaattgt caatgaaatg cttgagagag
    39061 ggtttaagtt tggcaagcta gacctttaca agagcgaggc aactgagttt caaattgaag
    39121 gggataccct aattccacct tttattgcct tagaaggctt gggagaaaac gttgctagac
    39181 aaatcgtcaa ggctcgccaa gatggtgaat ttctatcaaa aatggaatta cgcaagcgtg
    39241 gtggtgcttc tgccactcta gttgataaga tggacgagct gggcatttta ggaaatatgc
    39301 cagatgacaa tcagctgagt ctatttgatg actttttcta agattgcaca gccctaatat
    39361 tgtctatgtt agcttgtcat acagtgaaga gcagggcagg aaggcttcct gtcctctttt
    39421 tgtcaatacg caaagaaagc ccaaaaaaga acgaggaaaa gcatgaatga attagacaaa
    39481 aatcctgcct taaaggcaat ggttgttttt agaaaagcac agcgtacctt agatgctcaa
    39541 agctccgcct tttttcaaaa ggccaatctg actcctaccc aatttagcgt cttagaggtg
    39601 ctttattcca aaggaagcat gagaattaac aagctcatcg gttctctctt ggcaacctct
    39661 ggcaatatga ccgtagtgct gaaaaatatg gagagaaatg gctggatcag ccgctgccaa
    39721 gatgctaaag ataagcgtgc ctgcttggta cagctaacgc cagagggcaa agccttgatt
    39781 gagactatcc tacctgagca tatcaaacgt gttgaagccc ttttttcagt gctgacagag
    39841 actgagcaaa aacaattgat tacgctttta aagaaattta aagaactcta agcaaatggc
    39901 tttacaggat ctcccaagta ggatataatc actacatagt acaaaaagat actaactagt
    39961 cataataagt catcaagaca gcagatggct agttaccaga taatcaatgg gagacaaagc
    40021 atgaaacaaa ttttaatcat taatggttca ttacggacag gttcatttaa tcatcagctt
    40081 gctcaagcgg ctgagcagct acttgaaggc aaggcagctg tatcttactt ggactgggaa
    40141 caggtaccta tgtttagtca ggatttagaa gcaagcaccc ctgagtcagt ggcaggcgta
    40201 cgagaagcca ttcaagcagc agatgctatc tggatttttt cacctgtcta taattttgca
    40261 atcccgggct ctatcaaaaa cctattagac tgggtatcac gcgcccttga tttgtcagac
    40321 ccatcaggac catcagcaat caatggtaag gtagttaccg tatcatctgt tgctaatggt
    40381 gggcacgagc agctatttgc gcaataccag gacctgctgc cctttatccg tacgacagta
    40441 gttggtaact ttaccaaagc cgctgtcaat ccagaagcat gggcgacagg tgttcttgat
    40501 atttctgagg aaacaaggca aagccttgca gcacaggcag aagcccttct tgaagccatt
    40561 cactaagact ctctgagcat taaacagata aagctgcagc taggatcaaa aagcagctag
    40621 acacataaaa agagcttaaa ccagaaatgt acggcactcc aaaagctaga caaaaactct
    40681 agcgattggg gtacaggtca aaacggtttt aagctctttt ttagacttat tttatagtag
    40741 taacttaatt aagaattagc ataccctctt tagcctcaaa ggggtttttc gcattaatac
    40801 ggtcatagaa taagacacca ttaatatgat caatctcatg ctgaaccacg atagcattgt
    40861 agccctttag cttaatgcgg tgcttttcat tgtgcttatc gtaatattcc actgtcacac
    40921 gcgcatgacg gacgacatag ccttccacca cacgatcaac agacaaacac ccctcaccgt
    40981 cagcaagagc agcgtcttga acagaatgag acacaatttt aggattatag agcacttcct
    41041 ccatgctgta agcctcctta ggtggattgc cctcgctgtc ttcaggattt ggaaccagaa
    41101 cagcgatgat acgctttgac acatcaatct gaggtgctgc tagaccaact cctgctcgaa
    41161 gccctaattt ttctcccatg acagggtctt gagaatgctt taaaaattgc atcatttttt
    41221 cacctaaaat gatgtcatca tcactaagag gaaactcgac ctccttagcc acagcacgaa
    41281 gcgtaggatt gccttcgcgg ataatatcat tcatatcaat gagatgctgt gctttaatta
    41341 atttatcttg tgcagacatt ttgcctccct ttttttatat ttgataatgg ctttactata
    41401 tcacaaaatc cttattttta aaagataagg caggccagtg atgacgatat tagctaactc
    41461 tatcagatat attaaattat ttaaaaaata gttcgttaat tagcacgaca tatatataag
    41521 aaatacacag gaattctaat aattaataga taaaaaatga taatcgttcg taaataaatc
    41581 aaacatctaa tctaaaaaaa ttatattgtt ctgattgttc ggtaattaaa gcaatagcgc
    41641 ttgtcgaaaa actaatgttc tcttaatatc aggtagccat gccaagggtt ttgtgttaaa
    41701 gtataggacg ttcaaaaaat gaaatggaga gactaatgag aacacaattg aaaaaattgc
    41761 tggcaggaac agcagcaggt accctgctgc tgtttaacct gacctgcgga atgattaatg
    41821 cttttgcaga gcagtattac gggtggagtg acgggagtag cagctatccg agtgctttgt
    41881 atgttacacc ggtaggagat actacgaaaa agatagctat tcctgtttat tgctttgact
    41941 ataagtttca ggagccactt gcttggaaag aaataactca accgtcacac ttgattgtct
    42001 atgataagta tgatggcaaa aatttgatgg cagcactggt tgaaaaacct aatatggtaa
    42061 gctatgagac taaaactaaa cttcaaacac ttttaaagac aaagtcaaat ctaataactg
    42121 caattttaag tagaggttat ccaaacaaaa gtttttttga taagtataaa aaattaactg
    42181 atgaagataa aagacgagtg acacaatgtg ctctttggta tcatactgac aatatttcag
    42241 aacaagatct tatcacaaaa catttggatg gggattcagg tgaaaaaagt caagcgctaa
    42301 aggagttaat aggggttgta aaaaatactt ctaatgagtt aggagaggga ttaaccttct
    42361 atactcgtta taatgataga tatggtccta aatatcaaaa cctaataggc tcaattattg
    42421 ttcccgaaga gcctcagaat gatcttgaaa ttggtggtgg aaatgttatt gatttaaact
    42481 accaatctgg accaatggta gaagaaggtg gtcattcagg tggcaaggaa gaggtcgagg
    42541 acactaaaaa gcctgatgtg attattggtg gtcagggaag cgttactgag actactgagg
    42601 atactcaaaa gggtatgagt ggcagtactg agactcagcc agaggttgag gatactaagc
    42661 agccacaatc agatattatc ctaggcggac aaggcaatgt gattgacaca actgaaaata
    42721 cccaagaggg catgggtggc caatcaggtg atactacaga gactgaggat accaagcagc
    42781 cacaatcaga cattatccta ggtggacagg gcaatgtaat tgacaccact gaaaatactc
    42841 aagagggtat gagtggttcc aacaatggtc aaacatttga ggaggacaca cgtcctaagc
    42901 tggaattcca ttttgataat gaagtgccta acgatgatga cgctcctaaa ccagagcaac
    42961 cagaacagcc agagaagccg gagcaaccaa ggaagccaca gcaggagcag caaagcctac
    43021 cacgtccaat agagggcaac cagtcattgc caaaaacaca tgaggcaaaa ggtgtactgg
    43081 ctctagtagg agtaggaatc cttgctatgc taggactagg cttttggttt agaccttatc
    43141 aaaaagacta aatcaaggct cagcagctat ttaagctaaa cagctgtgct cagctaaatg
    43201 ataaaacaat taagattgga gaatgtggct attagtagct tctccaatct tttttgatag
    43261 cagcatgtgc tttttctgcc gtattttatt gagaataata gttgaccagt ctaggcgatt
    43321 ttgctagaat agagaggtcg caagacagac taactttttc ttggttttag gagtgccaac
    43381 cctaaaactc ggattaagca aaaaaggaga attattatgg caatctcaaa agagaaaaaa
    43441 aatgaaatta ttgcacaata tgcacgtcac gaaggtgaca caggctcagt tgaggttcag
    43501 gtagctgtcc ttacttggga aatcaaccac ttgaacaacc acatcaagga gcacaaaaaa
    43561 gaccacgcaa cttatcgtgg attgatgaaa aaaatcggac accgtcgtaa cctattagca
    43621 tacctacgtc gtacagatgt taaccgttac cgcgagttaa tccaatcact tggacttcgt
    43681 cgttaattgg cttgacagag gtcattttag agataaccaa gttctattga aaaaagatct
    43741 gctagtgtac tgacccccaa aagttggaca cgacatatta
//
LOCUS       DARYNN010000014        39772 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.014, whole genome shotgun sequence.
ACCESSION   DARYNN010000014 DARYNN010000000
VERSION     DARYNN010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39772)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39772)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39772
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.014"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            65..778
                     /locus_tag="TVB59_000686"
     CDS             65..778
                     /locus_tag="TVB59_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1009614.1"
                     /translation="MLNETNTKQVELSKATGIPPSTLTGYVKGTSLPIPGNVQKIADY
                     FGLMKSDIDPRFAPRKKNHELKIPTSPLVKKITTTVVELNVPRKQKVLDFATDQLKEQ
                     KNKMTSMEKKLYEYKVYEKLSAGTGYGYFGDGNYDTVFYEEELDYDFASWVFGDSMEP
                     TYLNGEVVLIKQTGFDYEGGVYAVEWDGQTYIKKVYREKDGLRLVSLNKKYKDKFAPF
                     SEDPRIIGKIVGNFMPKEY"
     gene            787..1956
                     /locus_tag="TVB59_000687"
     CDS             787..1956
                     /locus_tag="TVB59_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HEL1009615.1"
                     /translation="MGLFNFGKIKDVALEKKLQKLQQKIENEKEKLREIKEEIALAND
                     TLDLQEYGFFERQYKFSHSTKYKDALDTLRMKQKTLIKNGEATSIISPMTLDGSAAKG
                     KAMQNQLRKAAIRGFNGEADALLVKVSVVNVDKKVQTLQKAFEQLNKMYERNLIQLTF
                     KYLDLKAQELRLAAEYELQKQEEKEILREQRAREREDKKLQAEITAKRKQLEKDRKHF
                     LQMVKNVEVMLANASPKEQEKLQLQLIEYQNKLSELDKIEEDIDYREGHATAGYVYVI
                     SNIGAFGEDVYKIGVTRRLDPMDRIRELGSASVPFTFDVHALIFSEEAFALESELHNK
                     FEAYKVNKINSRKEYFRVPFAKIKEVLENHKELAIEITEEAEAFEYRQSILKNGG"
     gene            1959..2162
                     /locus_tag="TVB59_000688"
     CDS             1959..2162
                     /locus_tag="TVB59_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014611912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009616.1"
                     /translation="MKWLFLILFIGCGANAVNLSKKVNSDDEVDENNSHLISHSNEEI
                     PWNKKEQLYWGTASIVFLVLFII"
     gene            2294..3727
                     /locus_tag="TVB59_000689"
     CDS             2294..3727
                     /locus_tag="TVB59_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014570823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEL1009617.1"
                     /translation="MITTRKVAIYVRVSTTNQAEEGYSIQGQIDSLIKYCEAMGWIIY
                     EEYTDAGFSGGKIDRPAMSKLITDAKHKRFDTILVYKLDRLSRSVRDTLYLVKDVFNQ
                     NNIHFVSLQENIDTSSAMGNLFLTLLSAIAEFEREQITERMTMGKIGRAKSGKTMAWT
                     YTPFGYDYNKEKGELILDPAKAPIVKMIYTDYLKGMSIQKIVDKLNKMDYNGKDCTWF
                     PHGVKHLLDNPVYYGMTRYNNKLFPGNHQPIITKELFDKTQRERQRRRLGIEENHYTI
                     PFQAKYMLSKFLRCRQCGSRMGLELGRPRKKEGKRSKKYYCLNSRPKRTASCDTPLYD
                     AETLEDYVLHEIAKIQKDPSIASRQKHIEDHELKYKRERIEANINKTVNQLSKLNNLY
                     LNDLITLEDLKTQTNTLIAKKRLLENELDKTCDNDDELDRQETIADFLALPDVWTMDY
                     EGQKYAVELLVQRVKVDRDNIDIHWTF"
     gene            complement(3757..4925)
                     /locus_tag="TVB59_000690"
                     /pseudo
     CDS             complement(3757..4925)
                     /locus_tag="TVB59_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623352.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
     gene            4981..5622
                     /locus_tag="TVB59_000691"
     CDS             4981..5622
                     /locus_tag="TVB59_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEL1009618.1"
                     /translation="MEDYKTIMTDGLFEESIKKSRFICQIKRVYTEEEARAFIADIKK
                     KHYKANHSCSAMIIGDKGQTKRSSDDGEPSGTAGIPMLSVLERQELTNLVAVVTRYFG
                     GVKLGAGGLIRAYSGVTAAAIQALKVVEVKKQTGLAISLTYPQYQIYPNFLEQEALIE
                     MNTEFSDVVRTAIYFDPERLESISKALIEHYHGKVSFEEIESQRIEVPVLPAN"
     gene            5743..6669
                     /gene="cysK"
                     /locus_tag="TVB59_000692"
     CDS             5743..6669
                     /gene="cysK"
                     /locus_tag="TVB59_000692"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003063544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEL1009619.1"
                     /translation="MSKLYHNITELVGKTPIIKLRNTSPEEAADIYVKLEAFNPGSSV
                     KDRIALAMIEAAEKAGMIKPGDTIVEPTSGNTGIGLSWVGAAKGYRVLIVMPETMSIE
                     RRQIIQAYGAELVLTPGSDGMKGAIAKAEEIARETGAWMPSQFDNPANPKVHEETTGQ
                     EIIAVFGEKGLDAFVSGVGTGGTISGVAHALKAVNPDISIYAVEADESAVLSGEESSP
                     HKIQGISAGFIPNTLDTKAYDHIIRVASEAALATARSIGAKEGFLVGISSGAAVYAAI
                     QAAKELGKGKKVLAILPDNGERYLSTALYQFD"
     gene            complement(7056..7418)
                     /locus_tag="TVB59_000693"
     CDS             complement(7056..7418)
                     /locus_tag="TVB59_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEL1009620.1"
                     /translation="MKIGDKLHGTITGIKPYGAFVALENGTTGLIHISEIKTGFIDNI
                     HQILRLGEAVLVQVIDYDEYSHKVSLSLRTLEEEKHHVSSHHRFSNSRYKIGFKPLEA
                     SLPNWIEEGLDHFKQEKS"
     gene            complement(7418..8818)
                     /locus_tag="TVB59_000694"
     CDS             complement(7418..8818)
                     /locus_tag="TVB59_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL1009621.1"
                     /translation="MDAKLKYKAKKIKMVFFDIDDTLRVKNTGYMPESIQRVFKELKK
                     KGILTGIASGRARYGVPKEVQDLQADYCVKLNGAYVKDNQKNIIFQAPIPADTVVAYK
                     KWANAVGIDYGMAGRHEAVLSARNEMISDAIDKVYSTLEVCPDYNEHHDVYQMWTFED
                     KGDDLQLPVELAEQLRLVRWHDHSSDVVLKGTSKALGVSKVVEHLGLRPENILVFGDE
                     LNDLELFDYAGISIAMGVSHPQLQEKADFITKTVEENGILYALEELGLIDKELHFPQL
                     DLAGHEGPRVVMKTNHGELTLALFPEHAPKTVANFLGLAKEGYYNGVIFHRIIADFMI
                     QGGDPTGTGMGGQSIYGQSFEDEFSEELYNLRGALSMANAGPNTNGSQFFIVQNTSLP
                     YSQKELERGGWPKDIAAAYAEHGGTPYLDRRHTVFGQLADEASYQVLDNIAAVETGAQ
                     DKPKEDVVIEAIEVFD"
     gene            complement(8851..9492)
                     /locus_tag="TVB59_000695"
     CDS             complement(8851..9492)
                     /locus_tag="TVB59_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1009622.1"
                     /translation="MSNITVILVDDHEMVRMGLKSFLNLQQDVDVIGEASNGREGVEL
                     ALELRPDVVVMDLVMPELGGVEATLEILSKWKEARVLVLTSYLDNEKIYPVIDAGAKG
                     YMLKTSSAAEILNAIRKVAKGELAIETEVDKKIKAHDQQPNLHEELTAREYDILHLLA
                     KGYDNQTIADELFISLKTVKTHVSNILAKLQVDDRTQAVVYAFRHHLVPQDDH"
     gene            complement(9485..10489)
                     /locus_tag="TVB59_000696"
     CDS             complement(9485..10489)
                     /locus_tag="TVB59_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL1009623.1"
                     /translation="MKKRYYALVWLYSTITILSIVFVVMDNLGITFDYLRSHLWQLER
                     LVFSVVLLIISVTLLLLLLWIILDDNSKRSINKNLRRILNNQRIHLEETSEINTNLTR
                     LSAKMSHITTNIQKKENAYILDSQKIVQQERKRIARDLHDTVSQELFASSMILSGVSM
                     SLDQMDKEQLQQQLVTVEAMLQNAQNDLRILLLHLRPTELANRSLSEGFTMILKELTD
                     KSGIEVVYKENIGTLPKAIEDNLFRIAQEFISNTLKHAKASRLEVYLNQTPTELQLKM
                     VDNGVGFDMGQVRELSYGLKNIEDRVNDLAGTLRLISQKGKGVSMDIRLPLVMGDEDE
                     "
     gene            complement(10486..11178)
                     /locus_tag="TVB59_000697"
     CDS             complement(10486..11178)
                     /locus_tag="TVB59_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEL1009624.1"
                     /translation="MKKFQFFLLVECMLLAMGIMTILANDLSSFILILVLILLALRFY
                     NQDTRNSFLLTVSLLLLFLIFMLNPYIIMAVLLGIVYVIINHFSQVKKKNRFALIRFA
                     EEKMTVRQVKNQWLGAANYESDYYSFEDINIIRASGNDTIDLTNVIVTGMDNVIIIRK
                     IFGNTKILVPIDVAVTLEVSSIYASVDFFELQEYDLRNESITLGEAEDSSLKKVKIIV
                     STIAGNVEVARR"
     gene            complement(11311..13206)
                     /gene="pknB"
                     /locus_tag="TVB59_000698"
     CDS             complement(11311..13206)
                     /gene="pknB"
                     /locus_tag="TVB59_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEL1009625.1"
                     /translation="MIQIGKLFAGRYRILKSIGRGGMADVYLANDLILDNEDVAIKVL
                     RTNYQTDQVAVARFQREARAMAELNHPNIVAIRDIGEEDGQQFLVMEYVDGSDLKKYI
                     QDHAPLSNNEVVRIMEEVLSAMTLAHQKGIVHRDLKPQNILLTKSSVVKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSIIDENPNVPQALENVVIRATAKKLSDRYRSTFEMSRDLMTALSYN
                     RSRERKVVFDDVESTKPLPKVTPTPVTAPKVSNASQASAAVDARLEQTSQMDTLQKPQ
                     KKKKNGRFLGTLLKILFSFFVVGVALFAYLVLTKPTTVKVPDVTGSSLNAAKQVLEEA
                     GLKVGKVHQIESDTVSEDQVVKTNPQAGSAKRKGSSVDLYLSIGNKGFEMENYKGQDY
                     QDVMTSLTETYGVPKSKIKIERIVTNEYPENTVISQSPSAGEKFNPAGKSKITLSVAV
                     GDTVIMPMVTEYSYADAVNTLTALGIDAARIKAYVPSSSSPTGFVQVSSPSSKAVVSG
                     QTPYYGTQISLSEKGDISLYLYPEETRASSSSSSSDTSAPNPSAGDTTDSSSHTELGQ
                     NDAVTTP"
     gene            complement(13203..13943)
                     /locus_tag="TVB59_000699"
     CDS             complement(13203..13943)
                     /locus_tag="TVB59_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEL1009626.1"
                     /translation="MKISLKTDIGQKRSNNQDFINKFDNKKGITLVILADGMGGHRAG
                     NIASEMTVTDLGREWVKTDFTELSQIKDWLLTTIEAENQRIYDLGQSEDYKGMGTTVE
                     AVALVDSNAIYAHIGDSRIGLVHEGNYSLLTSDHSLVNALVKAGQITEEEAASHPQKN
                     IITQSIGQASPVEPDLGVKVLEKGDYLVINSDGLTNMIANEEIVDILCQDISLDEKNQ
                     ALIDLANQRGGLDNITVALVHKESGEAE"
     gene            complement(13981..15303)
                     /gene="rsmB"
                     /locus_tag="TVB59_000700"
     CDS             complement(13981..15303)
                     /gene="rsmB"
                     /locus_tag="TVB59_000700"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEL1009627.1"
                     /translation="MANDWKKSARGQALLIVEDIFDHGAYSNLALKHQLANQFLSDKD
                     KALVTEIVYGTISRKITLEWYLAHYIEDRDRLDKWVYYLLMLSLYQLAYLDKVPAHAI
                     VNDAVNLAKARAHGRGADKLVNAVLRQLTNKPLPDIKSIKRKNKYYAVAYSVPVWLVK
                     KLIDQFGEERAVAIMESLFVRSRASIRVTDLTKLDEIKQATGSEQSLLARTGLTKRAG
                     NFAASSYFINGDITIQDETSQLVAPTLDIQGQEMILDACSAPGGKTAHIASYLTSGKV
                     VALDLYEHKLALVNENAKRLGVADRIETKVLDAREVHKHFAKNSFDKILVDAPCSGIG
                     LIRRKPDIKYNKEGQDFQQLQEIQLEILSSVCQTLRKGGIITYSTCTIFDEENFQVID
                     KFLQRHPNFEQVTLKHAQADIVKDGCLMITPEQYQTDGFFIGQVRRVL"
     gene            complement(15293..16228)
                     /locus_tag="TVB59_000701"
     CDS             complement(15293..16228)
                     /locus_tag="TVB59_000701"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEL1009628.1"
                     /translation="MTRLIFMGTPQFSATVLQGLLEKPAYDILAVVTQPDRAVGRKKD
                     ITMTPVKKLALAHQLPVFQPEKLSGSQELADIMALGADGIVTAAFGQFLPTVLLDSVT
                     FAVNVHASLLPKYRGGAPIHYAIINGDKEAGVTIMEMVKEMDAGDMISSASLPILDTD
                     NVGTMFDKLAILGRDLLLKTLPDYLSGDLKPVPQDHSQATFSPNLSAEEERLDWSKPA
                     REVFNHIRGMNPWPVAHTLLDGQRFKIYEAELAEGSGSAGQIIAKTKKALVVAAGEGA
                     LSLTLVQPAGKPKMPIVDFLNGIGRSLEVGDVLGE"
     gene            complement(16295..18679)
                     /locus_tag="TVB59_000702"
     CDS             complement(16295..18679)
                     /locus_tag="TVB59_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEL1009629.1"
                     /translation="MQHIAQVIVDIPLMQTDKPFSYLIPDELLSLVKIGSRVHVPFGN
                     GNRLLQGFVIGFSSQSTQQLKAIWSVLDAEPVLNQEQVALAEQLRQTVFSYKITLLKA
                     MLPSLLNSHYDRLLTPTADLAAADLADVFSNGDSLLYSKLSPEQEGRVLRLIQSGKIR
                     ATYLAKDKKTIKTETYYQVNRLALQEHKISNRAKKRQALKAYLLANPQKDKLAKLYQD
                     YSREVVSYFVTNQLIELEERRVNRSEDYFNHIKAAPLLKLNQQQQQAVDQITKAVGRE
                     AKPFLLEGITGSGKTEVYLHVIAHVLEQGKTAIVLVPEISLTPQMTSRFISRFGRQVA
                     IMHSGLSDGEKFDEWQKIKTGQARVVVGARSAIFSPLENIGAIIIDEEHEATYKQESN
                     PRYHARDVALIRARHHKAALVMGSATPSIDSRARASKGLYQFIQLTERANPLASMPQV
                     EIVDFRDYIGQQEVSSFTPYLIDKLKERLARKEQAVLMLNRRGYSSFIMCRDCGYVDQ
                     CPNCDISLTLHMDTKTMNCHYCGFQRAIPKLCPSCQGKSIRYYGTGTQKAYDELKQVL
                     PEARILRMDVDTTRKKGSHEAILSQFGNGDADVLLGTQMIAKGLDFPNVTLVGVLNAD
                     TSLHLPDFRASERTFQLLTQVAGRAGRADKPGEVLIQTYNPEHYAIQLAKKQDFEAFY
                     AYEMGIRRKLGYPPYYFTVGLTLSHKSEQEVVKKAYQLLTILKQGLSDQIRILGPTPK
                     PIARTHNLYHYQIILKYRFEDQLEATLNQILDWSQEQDNRELKVIIDQEPQSFM"
     gene            complement(18743..19060)
                     /locus_tag="TVB59_000703"
     CDS             complement(18743..19060)
                     /locus_tag="TVB59_000703"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000979238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEL1009630.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILQAKRAHELEAGAAPTQSFKSV
                     KSTLQALEEIESGNVVIHPDPAAKRAAVRARIEAERLAREEEERKIKEQIAKEKEEEG
                     EKI"
     gene            complement(19085..19711)
                     /gene="gmk"
                     /locus_tag="TVB59_000704"
     CDS             complement(19085..19711)
                     /gene="gmk"
                     /locus_tag="TVB59_000704"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEL1009631.1"
                     /translation="MSERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFEYSVSMTTRPQ
                     RPGEVDGVDYFFRTREEFEELIKNGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKAKVPDGVFIFLTPPDLDELQDRLVGRGTDSQEVIAKRIERAKEEIALM
                     REYDYAVVNDEVPLAAERVKRIIETEHFRVERVIGRYDQMIKTTKSLR"
     gene            complement(19873..21483)
                     /locus_tag="TVB59_000705"
     CDS             complement(19873..21483)
                     /locus_tag="TVB59_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEL1009632.1"
                     /translation="MLINIITLLVCGLIGVILGYALISIRLKSAKEAAELTLLNAEQD
                     AVDIRGKAKADAAHIKKTAQRESKASRKELLLEAKEEARKYREEIEQEFKSERQELKQ
                     LETRLAERALTLDRKDENLSSKEKVLDSKEQSLTDKSKHIDERQAQVEKLEEDKRAEL
                     QRVAAMTIAEAREVILMETENKLTHEIATRIRDAERDIKDRTDKTAKDLLAQAMQRMA
                     GEYVTEQTITSVHLPDDNMKGRIIGREGRNIRTLESLTGIDVIIDDTPEVVVLSGFDP
                     IRREIARMTLESLIADGRIHPARIEELVEKNRLEMDNRIREYGEAAAYEIGAPNLHPD
                     LIKIMGRLQFRTSFGQNVLRHSVEVGKLAGILAGELGENVALARRAGFLHDMGKAIDR
                     EVEGSHVEIGMEFARKYKEHPVVVNTIASHHGDVEPDSVIAVLVAAADALSSARPGAR
                     NESVENYIKRLRDLEEIATSFDGVQSSFALQAGREIRIMVQPEKISDDEIVVLSHKVR
                     EKIENNLDYPGNIKVTVIRELRAIDYAK"
     gene            21640..22125
                     /locus_tag="TVB59_000706"
     CDS             21640..22125
                     /locus_tag="TVB59_000706"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEL1009633.1"
                     /translation="MPKEVIVESFELDHTIVKAPYVRLISEEFGPQGDVITNFDVRLV
                     QPNQAAIETAGLHTIEHLLAKLIRQRIDGMIDCSPFGCRTGFHLIMWGKHSSTDIAKI
                     ITSSLEEIATSITWEDVPGTTIESCGNYKDHSLFAAKEWAQLILKQGISDDPFNRHVT
                     S"
     gene            complement(22270..23721)
                     /locus_tag="TVB59_000707"
     CDS             complement(22270..23721)
                     /locus_tag="TVB59_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009634.1"
                     /translation="MSEKSKAFESEAESQNLELHEAKKMTIGEAVRKDSELKAGITED
                     DSVLDKYIKRHRNEVSSQKFDAKYMELDTASLDNFIKKQREELSKAGLVDVEPVDEAS
                     TEEKPAGETSFIEPLAARADTSAAATDSASDFTGQLADDAVSERPAEVESILSDSYAS
                     RRSKKKKPLFAILLATLTLVASAFALNHIYQLSKHKPQSKATVSKKARSKASTANQTN
                     KTKANAKAFEDLYKTFFTDNDKTTLKNSAFDQLPNLETALKRLEGTAYYDKAKEKVTG
                     LKKQVTAIQAVNGKFTTAAIVNGEKIAAEVKADANFDDLASDTLTTGNAKLDSLLQSS
                     IKAGREQLASRSATQAASTPAASALPASPAAPEVPAVPAPVAPMYGITGYDPSILQRD
                     LSRVPYNQAMIADTGNPAWAFNPGVLERIVATSQARGYISGNDYILEPVNIINGNGYY
                     NMFKPDGTYLFSLNCKTGYFVGNGKGHAEDLDY"
     gene            complement(23735..24889)
                     /locus_tag="TVB59_000708"
     CDS             complement(23735..24889)
                     /locus_tag="TVB59_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEL1009635.1"
                     /translation="MKEQFTLVATAAAGLEAVVGKELRALGFDCRVDNGKVFFEGDIE
                     AIAKANLWLRAADRIKIIVGQFPARSFEELFQGVFALDWEHYLPLGARFPIAKAKCVR
                     STLHNEPSVQAITKKAIVRKLQQHFHRPEHIPLQEVGAEFKIEVSILKDQATLMIDTS
                     GSSLFKRGYRVEKGGAPIKENMAAAILKLSNWFPDKPLVDPTCGSGTFCIEAALIGMN
                     IAPGFNRSFAFEEWSWVDKDRVQKVRDAAEKEANYDIELDISGFDIDGRMVELAKRNA
                     EEAGLADIITFKQMRLQDFRTDKINGVIISNPPYGERLLDDKAVDILYNEMVQVFAPL
                     VTWSKFILTSDDHFEQKYGQKADKKRKLYNGTLRVDLYQFYGERVKRNLI"
     gene            complement(24953..25321)
                     /gene="rnpB"
                     /locus_tag="TVB59_000709"
     ncRNA           complement(24953..25321)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="TVB59_000709"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            complement(25334..25657)
                     /gene="gpsB"
                     /locus_tag="TVB59_000710"
     CDS             complement(25334..25657)
                     /gene="gpsB"
                     /locus_tag="TVB59_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEL1009636.1"
                     /translation="MTGIIYSPKDIFEQEFKTSMRGFDKKEVDEFLDNVIKDYEYFNA
                     QIEALKAENEALKKAKAQVRDPLAGSSQAVSQPTRVAQSATNFDMLKRISKLEKEVFG
                     KQIIE"
     gene            complement(25779..26294)
                     /locus_tag="TVB59_000711"
     CDS             complement(25779..26294)
                     /locus_tag="TVB59_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEL1009637.1"
                     /translation="MTAILVTGYRSFELGIFSEKDKRVAIIKKAIERDLIAYLEEGVD
                     WFIFTGNLGFEQWALEVANDLKKTYPLKTATIFAFETHGSTWNDRNQQQLQQFRETDF
                     VKYSYPSYESPKQLKSYHHFLIHNTDGAYLFYDSEHETRLSYLVAAMKEQPCYPLSFL
                     NFERLNDIADE"
     gene            26370..26978
                     /gene="recU"
                     /locus_tag="TVB59_000712"
     CDS             26370..26978
                     /gene="recU"
                     /locus_tag="TVB59_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEL1009638.1"
                     /translation="MVNYPHNPIRQKVTPLQKQQKHKQVDFANRGMSFEASINATNAY
                     YLAKGIAVIHKKPTPIQIVKVDYPRRSRAKIVEAYFKQASTTDYSGIYKGHYIDFEAK
                     ETRQKTAMPMKNFHAHQIEHMAAVLKQKGICFVLLHFATLKETYYLPAKALIDFYQID
                     RGNKSMPLDYIRKNGFEVKLGAFPQVPYLDIIEQKFLGGDYN"
     gene            26965..29130
                     /locus_tag="TVB59_000713"
     CDS             26965..29130
                     /locus_tag="TVB59_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEL1009639.1"
                     /translation="MITINNPKILKFLKYTLGAILSLIIVTITLGGLLFAYYISSAPK
                     LSEAQLKSTNSSLVYDGNNHLIADLGSEKRENVTADSIPINLVNAIISIEDKRFFNHR
                     GVDLYRILGAAFHNLTSKTTQGGSTLDQQLIKLAYFSTNESDQTLKRKAQEVWLALQM
                     ERKYTKQEILTFYINKVYMGNGNYGMLTAAKAYYGKDLKDLSYAQLALLAGIPQAPSQ
                     YDPYTQPETAQSRRNIVLQQMYAEKNITKAEYEAAIATPISEGLQPLQQRASYPKYMD
                     NYLKQVIEQVKAETNKDIFTSGLKVYTNIIPEAQKKLYDIYNSEDYVYYPDADFQVAS
                     TVIDVTNGHVIAQLGGRNQDTNVSFGTNQAVLTDRDWGSTMKPITDYGPAIESGAYNS
                     TAQTTNDSVYYWPGTHTQLYNWDRRYYGWMTIQAALMQSRNVPAVRALEAAGLSYAQS
                     FLSDLGINYPEMHYSNAISSNNSSSDSKYGASSEKMAAAYAAFANGGLYYKPQYVNKI
                     EFSDGTSKVIENKGKRAMKETTAYMMTDMLKTVLTYGTGTAAAIPGVAQAGKTGTSNY
                     TDEELAQIVETHGLSPDYVGTMAPDENFVGYTNRYAMAVWTGYKNRMTPIYGYSLEIA
                     SHVYRNMISYLTGGYSDDWTMPSGLYRSGGFLYLSGTYTNSSDYTSSVYNNLYGNNSS
                     ASSQSSDEDTTEDSHSEANDSTTSSSEQQSSSTDDKKTN"
     gene            complement(29173..30507)
                     /gene="pepC"
                     /locus_tag="TVB59_000714"
     CDS             complement(29173..30507)
                     /gene="pepC"
                     /locus_tag="TVB59_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014678181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEL1009640.1"
                     /translation="MSVLTETFTEQLYANYEANAKYLALENAITHNGLLKSLETRQSE
                     IDNDFVFSIDLTKDKVSNQKASGRCWMFAALNTFRHKLISEFKLEDFELSQAHTFFWD
                     KYEKSNWFMEQVIATADQALTSRRVKFLLDVPQQDGGQWDMVVALFEKYGVVPKSVYP
                     ESVSSSNSRELNQYLNKLLRQDAQILRDVISAGADHQAVQAKKEELLQEIFNFLAMNL
                     GLPPRQFDFAYRDKDNHYHADKGITPQAFYEKYVGLKLSDYVSVINAPTADKPYGKSY
                     TVDMLGNVVGSPEVRYLNLDMERFKELAIKQMQAGESVWFGSDVGQVSDRQKGILALN
                     TYDFQAGMDIQLSQDKAGRLDYSESLMTHAMVLTGVDLDDTGKPIKWKVENSWGDKVG
                     DKGYFVASDAWMDEYTYQIVVRKDLLTADELAAYEAEPQVLAPWDPMGALAK"
     gene            complement(31196..32020)
                     /gene="nadE"
                     /locus_tag="TVB59_000715"
     CDS             complement(31196..32020)
                     /gene="nadE"
                     /locus_tag="TVB59_000715"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEL1009641.1"
                     /translation="MTLQEDIIRQLEVKAVIDPKQEIRQSVDFLKAYLLKHPFLKTYV
                     LGISGGQDSSLAGKLAQMAIEELRAETGDEQYQFIAVRLPYGVQADEADAQKALAFIQ
                     PDQALTVNIKEAVDGQLRALEAAGLEISDFNKGNIKARQRMISQYAIAGQTAGAVIGT
                     DHAAENVTGFFTKFGDGGADILPLFRLTKRQGKALLKVLKADPSLYEKVPTADLEDKK
                     PGLADEVALGVTYQEIDDYLEGHTISAEAQARIEDWWHKGQHKRHLPITIFDDFWK"
     gene            complement(32017..33477)
                     /locus_tag="TVB59_000716"
     CDS             complement(32017..33477)
                     /locus_tag="TVB59_000716"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEL1009642.1"
                     /translation="MYRDDSLTLHTDLYQLNMMQVYFEQGIHNRNAVFEVYFRREPFN
                     NGYAVFAGLQRIVEYLEQLTFSETDLAYLKELGYSPAFLTYLRELRLELTIRSAQEGD
                     LVFANEPIVQVEGPLGQCQLVETALLNIVNFQTLIATKAARIRSVIEDEPLLEFGTRR
                     AQEMDAAVWGTRAAIIGGADATSNVRAGKRFDIPVSGTHAHALVQAYGNDYDAFKAYA
                     SVHKDCIFLVDTYDTLRVGVPTAIRVAKELGDKINFLGVRLDSGDLAYLSKRVRQQLD
                     AAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVSIE
                     QADGTMRDTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITFTGVNVNDLEEIHM
                     FHPTYTYINKTVRDFDAVPLLVDIFDKGKLVYQLPSLKDIKAYARKEFDKLWDEYKRV
                     LNPQHYPVDLALDVWQNKMHLIDKIRKEACKRSDLI"
     gene            complement(33753..35147)
                     /locus_tag="TVB59_000717"
     CDS             complement(33753..35147)
                     /locus_tag="TVB59_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEL1009643.1"
                     /translation="MSTKEAKSTKELENGMVRGLQNRHVQLIAIAGTIGTGLFLGAGR
                     SIALTGPSIIFVYMITGVFMFLMMRAIGEMLYYDPDQHTFINFITKYIGPGWGYFSGL
                     SYWISLIFIGMAEITAVASYVQFWFPAWPSWLIQLVFLVLLSSINLIAVRVFGETEFW
                     FAMIKIVAILALIATAVFMVLTGFETHVGHASLANIVDHFSLFPNGKLKFFMAFQMVF
                     FAYQAIEFVGITTSETANPRKVLPKAIQEIPMRIVIFYVGALVSIMAIVPWYQLPTDE
                     SPFVMVFKLIGIKWAAALINFVVLTSAASALNSTLYSTGRHLYQIANETPNALTKALR
                     INTLSRQGVPSRAIIASAVAVGVSALINILPGVADAFSLITASSSGVYIAIYALTMLA
                     HWKYRQSSDFMPDGYLMPSYQLTTPLTLAFFAFVFISLFLQKSTYIGAIGASIWILVF
                     GCYSQLKCKKALKG"
     gene            complement(35267..36184)
                     /gene="trxB"
                     /locus_tag="TVB59_000718"
     CDS             complement(35267..36184)
                     /gene="trxB"
                     /locus_tag="TVB59_000718"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEL1009644.1"
                     /translation="MYDTLIIGSGPAGMTAALYAARSNLRVGIIEQGAPGGQMNNTSD
                     IENYPGYDHISGPELSLKMYEPLEKFKVENIYGIVQRVEDCGDYKRVYTEDTHYDTKT
                     VIVATGAKHRLLGVAGEEEYTSRGVSYCAVCDGAFFRNQELLVVGGGDSAVEEAIYLT
                     QFAKKVTIVHRRDQLRAQKILQERAFANEKLDFIWDSVVKEIQGNDIKVSNVVIENVK
                     TGQVTSHDFGGVFIYVGLIPVTQMVSELGITNQEGWIVTDDQMKTSIPGIFAVGDVRQ
                     KQLRQITTAVGDGAIAGQGVYHYIESLSS"
     gene            complement(36244..36471)
                     /locus_tag="TVB59_000719"
     CDS             complement(36244..36471)
                     /locus_tag="TVB59_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEL1009645.1"
                     /translation="MLVEIFRFYLEGLLLAAITMVMLCLLWILWRAVTKKDKTILQRQ
                     AFLYEMIMVAILTIPILSFAFMSILVVLKAK"
     gene            complement(36581..37324)
                     /locus_tag="TVB59_000720"
     CDS             complement(36581..37324)
                     /locus_tag="TVB59_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL1009646.1"
                     /translation="MIKVTHLTKSFSGQKILDDLTVTIEKGQVIALVGASGAGKSTFL
                     RSMNYLEQPDTGSITIDDFAVDFEHITKEDILTLRRKLAMVFQQFNLFERRTALDNVK
                     EGLKIVKKLSDQEATDIARAELAKVGLSDRENHYPRHLSGGQKQRVAIARALAMKPDV
                     LLLDEPTSALDPELVGEVERSIIDAAKAGQTMILVSHDMAFVYQVADRVLFLDKGKIL
                     EEGAPEQIFRHPKEARTKEFFANYAKTYI"
     gene            complement(37324..38127)
                     /locus_tag="TVB59_000721"
     CDS             complement(37324..38127)
                     /locus_tag="TVB59_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEL1009647.1"
                     /translation="MTSTFLTSGWAWYDKLISLIPEGKLFSWHAVFDAIPDIIRRLPI
                     TLGLTIAGAALGLFLALVFAIVKINRVRILYPIQAVFVSFLRGTPILVQLMLSYYGIP
                     LFLKFLNQRYGFDWNINAIPASIFAITAFAFNEAAYTSETIRAAIQSVHTGEIEAAKS
                     LGMTSAQVYRRVIIPNAAVVATPTLINGLIGLTKGTSLAFNAGIVEMFAQAQILGGAD
                     YRYFERYISVALVYWGISILIEQAGRLIEYNMAIKAPIPTNNSKIGELR"
     gene            complement(38504..39331)
                     /locus_tag="TVB59_000722"
     CDS             complement(38504..39331)
                     /locus_tag="TVB59_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEL1009648.1"
                     /translation="MTKQLQRALFFLLASLGLLAVVTSHEVTARQKEVIRVATDAATK
                     PFTYRKKHSVTGYDIEVLKRVFKGSKKYRLSIEVVPFPSILAGIDAGRYQIGANNFGY
                     SKERAEKYLFSSPISASHYALATKGKQQYKSLADLSGKKTQGIAGSNYMLILEKWNQS
                     HPDQKPIHLTYASESTPFTQRLQLLENGQLDFLFYDAISLTTVAEEQGFDVHVTKLKE
                     QADTAKDGLEYYVFANDQKGKALQSFVNKRLAKLKKSGQLRKLSQAFLGGDFISKVN"
BASE COUNT        11816 a         8997 c         7627 g        11332 t
ORIGIN      
        1 aagaggtaga ttaacacctc aagaaataga ggcgttagga ttcttttcga gcaaattcaa
       61 tgatctgctc aacgaaacaa atacaaagca agttgaactc tcaaaggcta caggaatacc
      121 accaagtacg ctcacaggtt acgtaaaagg gacatcttta cctattcccg gtaatgtcca
      181 aaaaatagcc gattattttg ggttaatgaa atcagatata gatccaagat ttgcacctcg
      241 taagaaaaat cacgaactta agattcctac ttctccactt gtcaaaaaaa taaccacaac
      301 tgtcgtggaa ttaaatgttc ctcgtaagca aaaagtttta gactttgcaa cagatcaatt
      361 aaaagaacaa aaaaataaaa tgacttctat ggagaaaaaa ctctatgagt ataaagttta
      421 cgagaagctt tcagctggga caggttatgg atattttggt gacgggaact atgatactgt
      481 cttttacgaa gaagaattag actacgattt cgcttcttgg gttttcggcg attctatgga
      541 gcccacttat ttaaatggtg aagttgtgct tataaagcaa actggctttg attacgaagg
      601 cggtgtctat gctgttgaat gggacggaca aacctatatt aagaaagttt atagggaaaa
      661 agatggatta agattagttt ctttaaataa aaaatacaag gataagtttg ctccttttag
      721 cgaagatccg cgtataatcg gcaaaatcgt cggcaacttt atgcccaaag aatattgagg
      781 tgtgttatgg gattgtttaa tttcggaaaa ataaaagatg tggctctaga aaagaaatta
      841 caaaagttac aacaaaaaat tgaaaatgaa aaagaaaaat tgagggaaat taaagaagaa
      901 attgcattag ccaatgatac attagacctt caagaatatg gtttttttga acgccagtat
      961 aaattttccc atagtactaa atataaagat gctttagata cgttacgaat gaaacaaaaa
     1021 acactcataa aaaatggtga agctacaagc ataatttccc ccatgactct agatggtagt
     1081 gcagcaaaag gtaaagcaat gcagaaccaa cttaggaaag ctgcaatccg cggctttaat
     1141 ggtgaagccg atgccttact agttaaagtg tctgtcgtaa atgtagataa aaaagtgcaa
     1201 actcttcaga aggctttcga acaattaaat aaaatgtatg aaaggaactt gatccaactt
     1261 acctttaaat atttagattt aaaagcacaa gaattgagat tagctgctga atacgaattg
     1321 caaaaacaag aagaaaaaga aattctaaga gaacagcgtg caagagaaag agaagataaa
     1381 aaacttcaag ctgagattac tgctaaaaga aaacaacttg aaaaagacag gaagcacttt
     1441 ttacaaatgg tcaagaacgt cgaagtgatg cttgctaacg cttctccgaa agaacaagag
     1501 aaattacaat tgcaattaat tgaataccaa aacaagctct cagaacttga taagattgaa
     1561 gaagacattg attatagaga aggacatgca acagctggat atgtctatgt tatttctaat
     1621 ataggtgctt ttggagaaga tgtttataaa attggagtaa caagacgttt agacccaatg
     1681 gatcgtattc gcgaattggg gagtgcatcg gtgcctttta cttttgatgt tcatgcgctt
     1741 atctttagtg aggaagcttt tgctttagag tctgagttac ataataaatt tgaagcgtat
     1801 aaagtaaata aaataaacag tcgaaaagag tactttagag ttccgtttgc taaaatcaaa
     1861 gaagttctag aaaatcataa agaattagct attgagatta ccgaagaagc tgaagcgttt
     1921 gaataccgtc aaagtatctt gaaaaatggg ggttaaatat gaaatggtta ttcctaattt
     1981 tatttatagg ctgcggtgct aatgctgtaa acctttctaa aaaagttaat tccgatgatg
     2041 aagttgacga aaacaacagt caccttatat cacattcaaa tgaagagatt ccttggaata
     2101 aaaaagaaca gctttattgg ggcactgctt ccattgtatt tttagtgctt tttataatct
     2161 aaacacaata ataaaaagcc tcacgctcaa ctttggtcga tgcgagcgtg aggcgaacgt
     2221 gtatagtaaa aacctgcttt gcagtaggtc tctttactat acccatttta acataaaaat
     2281 gaggtgaaaa acaatgatta caacaagaaa agtcgctatt tatgttagag tcagtacaac
     2341 aaatcaggca gaggagggct attcaataca aggtcagata gacagtttga tcaaatactg
     2401 cgaagctatg ggttggatta tatatgagga gtacactgat gctggctttt caggaggtaa
     2461 gatagaccgt cccgccatgt ctaaactaat tacagacgca aagcataaac gatttgatac
     2521 aatcttagtt tataagctag acagactctc ccgaagtgtc agagatactc tttacttagt
     2581 taaagatgtt tttaaccaaa acaatatcca ttttgtcagt ctgcaagaaa atattgacac
     2641 ttcttcggct atgggtaatc tattcctcac attgctatct gcaattgccg aattcgaacg
     2701 agaacagata acagagagaa tgacaatggg aaaaatcgga agagcaaaat ccggaaaaac
     2761 tatggcctgg acttataccc cttttggcta tgattacaac aaagaaaaag gcgaattgat
     2821 tttagatcct gcaaaagcgc ctatagttaa aatgatatat acagattatc tcaaaggtat
     2881 gtctattcaa aaaatagtgg ataaacttaa taagatggac tacaacggta aggattgcac
     2941 ttggtttcca catggtgtta agcatctatt agataatcct gtctattatg gtatgacaag
     3001 gtataataat aaattattcc ccggaaatca tcaaccaatt attacaaaag agctatttga
     3061 taaaacccaa agagaaaggc aacgcagaag attaggaatc gaagaaaacc actacacaat
     3121 accttttcag gcgaagtata tgctaagtaa atttttaaga tgtcgtcaat gtggctcaag
     3181 aatggggctt gagcttggca gaccaagaaa aaaagaaggc aaaagatcca aaaaatacta
     3241 ttgcctaaat agtaggccaa aacgaacagc tagttgcgac acaccacttt acgatgcaga
     3301 aaccttggag gattatgtgt tacacgagat agccaaaata caaaaagatc cgtcaatagc
     3361 gagcagacaa aaacatattg aggatcacga attaaaatac aagcgtgaaa gaattgaagc
     3421 taatatcaat aaaacagtga atcaactctc taagctaaac aatctttatc ttaacgatct
     3481 gataactctt gaagacctca aaactcagac aaacactctt atagctaaaa aaagattgct
     3541 agagaacgaa ctagataaaa cttgtgataa cgatgatgaa cttgacagac aagaaaccat
     3601 tgctgacttt ctcgccttgc ctgatgtatg gaccatggac tatgagggtc aaaaatatgc
     3661 tgttgagctg cttgttcaac gtgttaaagt tgatagagat aatatagaca ttcattggac
     3721 tttttaatgc caaaaattac aaagttttca acccttgatt tgaataagac tgctgcttgt
     3781 gtaaaggcga tgattggcta ataagacaaa gacatctacg gttggaaagg tcacacctct
     3841 ttccaaaatg gttgttgata taagtatagt gatttgtcct tgtctgaatt gctcaatgat
     3901 agccattcga tttgatgact gactggaagc atgagcaata gtttccttag gaaaatactt
     3961 gtggagcagc tgacagcatt gctcagccag ctcaataatc ggaaaaaaga ttaaaagagg
     4021 atagccggtt gccctttgtt ttttgactag ggtgatgaac cttctaggca atttcccacg
     4081 attgatagcc tctaaaaggg agaataatct ttgatacttt ggaacaacta agggcttgcc
     4141 atggaatctt cttgccaacg tcaatttgac aagctctttt tgctgacctt gcgctctaaa
     4201 tctcttgtag aggttgctgt taggtatact gtcactgcat ctgcttttgc agcctgatga
     4261 gcagcatggt ttaattgacg attattgaca aaggggaagg catctacttc gtcaataatg
     4321 agcagatcaa aagcatggta aaaggtcatc aattgatgtg ttgtggcaac gataatgggg
     4381 cttctatgat aaacctctga ctcagcatgc ataaggcaga cttgacagga aaagtcccgc
     4441 gatagtcgtt tttcaagctc tatgcaaaca tcaactcgtg gactagcaat gcagacccag
     4501 ccacccttat taacaactgc tgcaatagct tcatacatca tctctgtttt gccagcacca
     4561 gtaaccgcat gaactaaggt gtcttgcttg agcttaacat ggttagtaag ctgatgagag
     4621 atagctgcct gatatgtcgt gagctgtcct tgccacctca gataatgtcc ctttggaaaa
     4681 gaagccggtg gaaaatagag caaggggcga tcagattggt ttcgaccaaa aacaagacag
     4741 gctctacagt agtaagcacc gctaggcagc tgatgagcct tctcaattaa actgctacag
     4801 cgttggcagt ataacgttcc ctttttagtg atcatgcttt gtaagctgca agcccaggca
     4861 gaaacagcct ttgggcattg cctttcgggt aaaagacgtc catagtaatt ttcgatattc
     4921 tccatacctt attatccgaa ttattttgct aaatatcagc attttttgta aaattttctt
     4981 atggaagatt ataaaactat tatgactgat gggctttttg aggaaagcat caaaaaatct
     5041 cgctttattt gccaaatcaa acgcgtctac acagaagagg aggccagagc ctttattgct
     5101 gacatcaaaa aaaagcacta taaggccaat cattcctgct ctgctatgat tatcggagac
     5161 aaaggacaaa ccaagcggtc aagcgatgat ggtgagccat ctggtactgc tggtattccc
     5221 atgctatctg tcttagaaag gcaggaatta accaatcttg tagctgttgt gacacgctat
     5281 tttggaggtg ttaaattagg agctggaggg ctcattcgcg cttactccgg cgtaactgcg
     5341 gcagctattc aggccttaaa ggtcgttgag gtaaaaaaac aaactggact agcaatcagc
     5401 ctcacctacc ctcaatacca aatctatcct aattttctgg agcaagaagc attgattgaa
     5461 atgaataccg aattttctga tgtcgtcaga acagctattt actttgatcc tgagcgcttg
     5521 gagagtattt ctaaggcatt gattgagcat tatcatggca aggtttcctt tgaagagatc
     5581 gaatcgcaaa ggattgaggt ccctgttttg cctgccaatt agcatgaaca gtgatagcgt
     5641 ctctttatca ctacgatagt aaatggctat tttactttgt cgattattag ctatatactt
     5701 ttatataagc atgtattgat acaaggataa aaaggaggac ctatgtcaaa gctatatcac
     5761 aacattacag agttggttgg gaaaacccct attattaaat tgagaaacac cagtccagag
     5821 gaggctgccg atatttatgt caagctagaa gcttttaatc caggctcttc agttaaggat
     5881 cgcatagcac ttgcaatgat tgaagctgct gagaaagcag gcatgatcaa gccaggtgat
     5941 acaatcgttg agccaaccag tggcaataca gggattggct tatcctgggt tggggctgca
     6001 aaaggctacc gagtgctcat tgtaatgcct gagacaatga gtattgaaag acgtcaaatc
     6061 attcaagctt acggagcaga gctcgtttta accccaggta gtgatgggat gaaaggtgcg
     6121 attgctaaag cagaagagat tgccagagag accggtgctt ggatgccctc gcaatttgac
     6181 aatcctgcaa atcccaaggt tcatgaagag acaacagggc aagaaattat cgcggttttt
     6241 ggagaaaaag gacttgatgc ctttgtttct ggtgtgggaa ctggtggcac tatttctggc
     6301 gttgcgcatg ccttaaaggc tgttaatcct gatatttcta tctatgctgt ggaagcagat
     6361 gaatctgccg tcttatctgg tgaagagtct tctccgcaca agattcaagg gatttcagct
     6421 ggctttatcc caaatacctt agatacaaag gcctatgacc acatcattcg agtagcgtca
     6481 gaggctgccc ttgccactgc tcggtcaatc ggggctaagg agggctttct tgtaggcatt
     6541 tcttctggag ccgctgttta tgctgctatc caagctgcta aggagcttgg aaaaggtaaa
     6601 aaggtcttag ctatattacc agataatggt gagcggtacc tgtctactgc cctttatcag
     6661 tttgattaga ataatcatat aagcaccagc cctagcagct agaataagct ttcaagcata
     6721 aatcatcgct cttacttagt caccattaaa ggccagtcag ctagcatatg gaaaaatgct
     6781 tactttgatt cctttttaac aataaacata gcataccacg cctaagcgcc ccagagcttc
     6841 tagcttcttg gaaataggct ttcctagccg ctttcaccac agtaaaaaag actcaagcta
     6901 gtaggctaag atgttcaaag aggactagca atcacaattg gctttttttg aagatagctt
     6961 tgagataagt aaggtgactg gtccagagct gatagcaaaa aaccgaggaa cagttcatat
     7021 agctgtttct cggtttttta tgtttccaag tctgtttacg atttttcctg cttaaagtgg
     7081 tctaagcctt cctcaatcca attgggtaag ctggcttcaa gaggcttaaa gccaatctta
     7141 taacggctgt ttgaaaagcg atgatgactt gacacatgat gcttttcctc ctccaaagtt
     7201 ctcaaggaca ggctgacctt atgactgtat tcgtcatagt caatgacctg aactaaaacc
     7261 gcctcaccaa gtcttaggat ctgatgaata ttatcaataa atcccgtctt aatttctgaa
     7321 atatgaatga gacctgttgt cccattttca agggcaacaa aggctccata gggtttgatt
     7381 cctgtaatgg tcccatgcag cttatcgcca attttcatca atcaaatacc tcgatggcct
     7441 caatgacaac gtcctctttt ggcttgtctt gtgcccctgt ttcgacagca gcaatgttat
     7501 ccaagacctg ataagaggct tcatcagcca actgaccaaa tactgtatgg cgacgatcca
     7561 ggtaaggagt ccccccatgt tcagcgtagg ctgctgcaat gtcctttggc cagccaccac
     7621 gctctaattc cttttgagaa taaggaaggc ttgtattttg gacgataaag aattggctgc
     7681 cgtttgtatt tggtcctgca ttagccatcg aaagggctcc gcgaaggttg tacaattcct
     7741 ctgaaaactc atcctcaaag ctttgaccat agatggattg cccacccatt ccagtgccag
     7801 tcggatctcc accttgaatc ataaaatctg caataatacg atggaaaata acaccattat
     7861 agtagccttc cttagctaga cctaagaagt tagcaactgt ttttggagca tgctctggaa
     7921 ataaagccaa tgtcagctca ccatgatttg ttttcatcac cactcttggt ccttcatggc
     7981 cagccaaatc tagctgcgga aaatgtaatt ctttgtcaat caaacctaat tcctccaagg
     8041 catataaaat gccgttttct tcaactgttt tagtaataaa atctgctttt tcttgtaatt
     8101 gtgggtgaga aacccccata gcaatgctga tgccagcata atcaaatagc tctaaatcat
     8161 tgagctcatc accaaagacc aggatatttt caggccttaa gcccaaatgc tcaacaacct
     8221 ttgatacacc tagagcctta gaggtgccct ttaggaccac atcagaggag tgatcatgcc
     8281 accttactag gcgaagctgc tcagccaatt caacaggtaa ttgcaggtca tctcccttgt
     8341 cctcaaaggt ccacatttgg tagacatcat ggtgctcatt gtaatccggg catacctcta
     8401 gtgtggagta aaccttatca atagcatcac taatcatctc gttacgagct gataagacag
     8461 cctcgtgacg tcctgccatg ccataatcaa tgccgactgc attggcccat tttttatagg
     8521 ctacaacagt gtctgctggg ataggtgcct gaaagataat gtttttttga ttgtccttca
     8581 cataagcacc atttagctta acacaataat ctgcctgtaa atcctgaacc tccttgggca
     8641 caccatatct ggcgcgaccc gaagcaattc ctgttaggat cccttttttc ttgagctctt
     8701 tgaaaaccct ctggatagac tctggcatat agcctgtgtt ctttacgcgc agggtatcat
     8761 ctatgtcaaa gaaaaccatc ttgattttct tggccttata ctttagtttt gcgtccatac
     8821 tttcctccat gcaatagtac tattatagca ttaatgatca tcttgaggca ctaaatgatg
     8881 tcggaaagcg tatacaacag cctgagtacg atcatcaacc tgcaatttgg ctaaaatatt
     8941 tgacacgtga gtcttaactg tcttcaagga aataaaaagc tcatcagcaa tggtctggtt
     9001 atcatagccc ttggccaata aatgcaaaat atcgtattca cgcgctgtaa gctcttcatg
     9061 taaattaggc tgctgatcat gtgccttaat cttcttgtca acctccgttt caatggcaag
     9121 ctcgccctta gcaacctttc taatggcatt taagatttca gctgcacttg atgtttttaa
     9181 catatagccc ttagctcctg catcaatgac agggtaaatt ttttcattat caagatagga
     9241 ggttaacacc aacacccttg cttccttcca tttggagagt atttctaggg tcgcctctac
     9301 acctcctaat tcaggcatta ccaaatccat aaccacgaca tctggtctca attcaagggc
     9361 aagctcaact ccctcacgac cattagaagc ctcacctatg acatcaacat cttgctgcaa
     9421 atttaagaag ctttttaagc ccattcggac catttcatgg tcatcaacta atattacggt
     9481 tatattactc atcttcatct cccatcacaa gtggcagtct aatgtccatc gaaacgccct
     9541 ttcctttttg actaatcaaa cgaagcgttc cagccaggtc attcacacga tcttcaatat
     9601 ttttaaggcc atagcttaat tccctaacct gacccatgtc aaaaccaacc ccattatcaa
     9661 ccatttttag ctgtagttct gttggtgttt ggttcaagta cacctcaagg cggctcgcct
     9721 tagcatgctt gagggtattg ctgataaatt cctgagcgat cctaaagaga ttatcctcta
     9781 tggcctttgg cagagtgcca atattttctt tatagacaac ctcaatgccg cttttatcag
     9841 ttagttcctt gagaatcatc gtaaagccct ctgacaggct acgatttgcc aattctgtcg
     9901 ggcgcaggtg caataataaa atgcgtaaat cattttgagc attttgcagc atggcttcaa
     9961 cagtaactaa ttgttgctgt agctgctcct tatccatctg atctaggctc atagaaaccc
    10021 ctgacaaaat catcgacgaa gcaaacaatt cttgactaac agtgtcgtgc aggtctctag
    10081 cgattcgttt acgctcctgt tgaacaattt tttgactatc taaaatataa gcattctctt
    10141 ttttctggat attggttgtt atatgagaca ttttcgcaga aagtctggtc aaattcgtgt
    10201 tgatttcaga ggtctcctcc aaatgaattc tttgattgtt gagaatcctg cgtaaatttt
    10261 tattgatgct ccgcttgcta ttatcatcta aaataatcca caacaaaagc aacagcaagg
    10321 ttacagagat gataagcagc acaactgaaa acaccaagcg ctctagctgc cataaatggc
    10381 tccgcaagta gtcaaaggtg atccccagat tatccatcac aacaaaaaca attgataaaa
    10441 tggttatagt cgaataaagc cagaccaaag cataatacct ttttttcatc gtctagccac
    10501 ctcgacattt cctgctatag tggatacgat aatcttaacc ttctttaaac tgctgtcctc
    10561 ggcctctcct agggtgatgg attcatttcg taaatcgtac tcttgaagct caaaaaaatc
    10621 aacactagca tagatagagc tgacctctaa ggtaacagcc acatcaatag gcactaggat
    10681 ctttgtgttg ccaaagatct ttctgataat gatgacattg tccattccag tcacaatcac
    10741 atttgtcaga tcaatcgtat cattgccaga ggcacgaata atattgatat cctcaaagga
    10801 ataataatca ctttcatagt tagctgcgcc aagccattga tttttgacct gtcgcacagt
    10861 cattttttct tctgcaaacc gaatgagggc aaatcgattc ttctttttta cctgtgaaaa
    10921 atgattgata atcacataca caatccccaa cagaaccgcc ataataatat aagggttcag
    10981 cataaaaatt aagaataaaa gcaataagct aactgttagc aaaaagctat tgcgggtatc
    11041 ttgattataa aaacgcagag ccaataaaat caagaccaaa attaaaataa agcttgataa
    11101 gtcgttggcc aaaatggtca taatccccat agccagcagc atgcattcaa caagcagaaa
    11161 gaattgaaat tttttcatta gactccttcc attaccctga cattttatca aaaattaagc
    11221 aaaaattcac ccttgagtgg cattctagta aaaaagaata cctagcttag caactatggg
    11281 caagccagat attctatatc ctatttacgt ttacggtgtt gtaacagcgt cattttgacc
    11341 taattcggta tgactgcttg agtctgttgt atctccagct gatggattag gagccgaggt
    11401 atcagagctc gatgagctgc ttgatgcacg tgtctcctca gggtagaggt agaggctaat
    11461 atcacccttt tcagaaaggc taatctgggt accataatac ggtgtttgcc cactgacaac
    11521 cgcctttgag cttggggagc tcacctgcac aaagcctgtc ggagagctgg agcttggtac
    11581 ataggccttg attcttgcgg catcaattcc taaagctgtt agtgtattga ctgcatctgc
    11641 atagctgtac tcagttacca ttggcatgat gactgtatca cccactgcta cactgagggt
    11701 aatcttggat ttaccagctg ggttaaattt ttctcctgcg cttggagact ggctaataac
    11761 ggtgttttca gggtattcat ttgtcacgat acgctcaatc ttgatttttg actttggtac
    11821 gccataggtc tcagtcagac tggtcatcac atcttgataa tcctgtccct tataattttc
    11881 catctcaaag cctttatttc cgatcgaaag gtaaaggtca acgctggagc cttttcgctt
    11941 agctgagcca gcttgaggat ttgtcttaac cacctgatcc tcactaactg tgtcactttc
    12001 aatctgatgg accttaccga cctttagtcc cgcctcctcc aagacctgct tggcagcatt
    12061 gagactagag cctgtcacat caggaacctt aaccgtagtt ggcttggtca agaccaaata
    12121 agcaaaaaga gccacaccaa caacaaaaaa ggaaaacaag atttttaaga gtgttcctag
    12181 aaaacgccca ttttttttct ttttttgagg cttttgcaga gtatccatct ggctagtctg
    12241 ctcaagtcta gcatcaactg ccgcagatgc ctgactagca tttgatacct taggtgctgt
    12301 tacaggagtc ggtgttacct ttggcaaggg ctttgtgctt tcgacatcat caaagacaac
    12361 cttacgctca cgactgcggt tatagctaag ggctgtcatc aaatccctgc tcatctcaaa
    12421 ggtcgagcga taacggtcac ttagcttttt ggcagtagcc cgaataacga cgttttccaa
    12481 ggcttgaggc acattaggat tttcatcaat gatagagggc agcggctttt gaaaatgctg
    12541 caaagcaatc gtcacagcgc tatcgccatc ataaggaata tgccctgtta gcatttcaaa
    12601 gagcataatt cccatcgcgt aaatatcact ttgaatcgtc gctttagaac cacgcgcttg
    12661 ctcaggtgag aggtaatgca cacttcctag catagaattt gtctgggtta gactggtctc
    12721 tgcaaaggca acggcaatcc caaaatctgt aaccttaaca acacttgatt tggtcaaaag
    12781 aatgttttga ggctttaaat ccctgtgaac aattcctttt tggtgggcca gagtcatggc
    12841 agaaagaacc tcttccatga ttctcaccac ctcattgtta gataatggcg catgatcctg
    12901 aatgtatttt ttcaagtcag agccatcaac atattccatt actaaaaatt gctgtccgtc
    12961 ttcctcgcct atatcccgaa tggcaacaat attggggtga tttaattcag ccatggctcg
    13021 cgcttctctt tgaaaacgcg caacagcaac ctgatctgtt tgataattgg tccgcaagac
    13081 cttaatggca acgtcctcat tatccagaat caaatcgttt gctaaataaa catccgccat
    13141 accaccgcgg cctatagatt ttagaatgcg ataacgacca gcaaatagct tgccaatctg
    13201 aatcattctg cttccccgct ttccttatgc accaaagcaa cggtgatgtt gtctaggcct
    13261 cctctttggt ttgccaggtc aatcaaggct tgatttttct catcaaggct gatgtcttga
    13321 cataatatgt caacaatctc ctcattagca atcatattgg ttaagccatc actattaatc
    13381 actaggtaat cgcccttttc taaaaccttg acacctaagt ctggctctac cggtgaagct
    13441 tgacctatag attgtgtgat gatatttttt tgtgggtggc tagcagcctc ctcttcggta
    13501 atctgaccag ccttcactag ggcattaacc aaggaatgat cactggttaa aagactataa
    13561 tttccctcat gaaccaagcc gatacgagaa tcgccaatat gggcataaat cgcattagaa
    13621 tctactagag caactgcctc aacggttgtt cccattccct tatagtcttc agattgtccc
    13681 aagtcgtaga tacgttggtt ctctgcttcg atggttgtta acaaccaatc cttgatctga
    13741 ctaagctcag taaaatctgt cttaacccac tctctaccta ggtctgtaac ggtcatctca
    13801 ctggcaatat ttcctgccct atgacctccc ataccatctg ctaggataac aagggtaatg
    13861 ccttttttat tatcaaattt gttgataaaa tcttgattgt ttgagcgctt ttgcccaata
    13921 tcggttttta atgaaatctt catataatct tttctgacta ggtcagtctc ctcctaaata
    13981 ctacaagact cgtctgactt gcccaataaa gaagccatca gtctggtatt gctctggtgt
    14041 aatcataaga caaccgtcct tgacaatatc tgcttgtgca tgcttgagtg ttacttgttc
    14101 aaaattagga tgacgttgta aaaatttgtc aataacttgg aaattctctt catcaaaaat
    14161 cgtacaagtg ctataggtta ttataccacc ttttcgcagc gtttgacaaa cgctagacaa
    14221 tatctccagc tgaatttcct gcaattgctg gaagtcctgc ccttccttgt tgtatttaat
    14281 atctggctta cgcctgatga ggcctatacc agagcaggga gcatcaacta aaatcttatc
    14341 aaagctgttc ttcgcaaaat gcttatgaac ctctctagca tcaagcacct tagtttcaat
    14401 ccgatctgct acccctagac gcttagcatt ttcattcact aaggccagct tgtgctcata
    14461 caaatcaagg gccactactt tgccgctcgt caaataagag gcaatgtgag ctgttttccc
    14521 tccgggtgca ctacaagcat ctaaaatcat ttcctgccct tgaatatcca gcgtcggggc
    14581 aactagctga ctggtctcat cttggatcgt aatgtcccca ttgatgaaat aactgctggc
    14641 agcaaaattg ccagctctct tggtcagacc agtcctagca agtaatgatt gctctgatcc
    14701 tgttgcctgc ttgatctcat caagctttgt cagatctgtg acacgtatgc tggctctgct
    14761 tctcacaaaa agactttcca tgattgctac agctcgctcc tcgccaaatt ggtcgatcaa
    14821 ttttttgact agccagaccg gtactgagta agcaacagca tagtatttgt tttttcgctt
    14881 gatgctcttg atatctggta agggcttatt ggtcagctgg cgcaaaacgg cattgaccag
    14941 cttatctgct cctctgccat gagctctcgc cttggcaaga ttaacagcgt cattaacaat
    15001 agcatgagca ggcaccttgt ctaggtaagc cagctggtaa aggctaagca tcaagagata
    15061 ataaacccat ttatccagcc tgtctcggtc ctcaatatag tgagccagat accattctag
    15121 ggttatcttc ctagagatag tcccgtaaac aatctctgtg actagagcct tgtccttatc
    15181 acttaaaaac tgattcgcca gctggtgctt caaggcaagg ttagaatagg ctccatgatc
    15241 aaaaatatcc tcaacgataa gcagcgcctg tcctctagct gattttttcc aatcattcgc
    15301 caaggacatc acccacctct aggcttctgc caataccatt taaaaagtca acaataggca
    15361 tctttggctt gcctgctggt tgaacgagcg tcaaggatag agccccctca cctgctgcta
    15421 cgaccaatgc ttttttagtt ttagcgatga tttgcccagc agatccagag ccttcagcca
    15481 attcagcctc ataaattttg aagcgctgcc catctaataa ggtatgagcc accggccaag
    15541 ggttcattcc tctgatatga ttaaacacct ctcttgctgg ctttgaccag tccagtcttt
    15601 cttcttctgc tgaaagattg ggagaaaagg tggcttggct atggtcttga ggaactggct
    15661 ttaggtcacc agacaagtaa tcaggcaagg ttttcaataa taaatctcgt cctagaatgg
    15721 ccagcttatc aaacatggta ccaacattat cagtatctaa aattggaagg cttgcgcttg
    15781 atatcatatc cccagcgtcc atctccttaa ccatctccat aatggtaact ccagcttcct
    15841 tgtcaccatt gataatagca taatggatcg gagcgccacc acgatattta ggaagtaagg
    15901 acgcgtgcac attaacagca aatgtcaccg aatccaataa gactgttggt aaaaattgcc
    15961 caaaggctgc cgttacaatc ccgtctgctc ctaatgccat gatatctgct agctcctgtg
    16021 aaccagatag cttctcaggc tgaaaaacag gcagctgatg tgcaagcgcc agctttttaa
    16081 caggcgtcat tgtgatgtct tttttgcgac caaccgcacg atcaggctgg gtcacgaccg
    16141 ctaaaatgtc ataggctggt ttttctagta agccctgcaa aacagttgct gaaaattggg
    16201 gagtgcccat aaaaattaat cttgtcatct atgtcctcta ttttctttct ttttcattat
    16261 agcatagctt ggcgcaaagt ccggtaaaga acacttacat aaagctctgt ggctcctgat
    16321 caatgataac ctttagctcg cgattatcct gctcttggct ccaatcaaga atttgattca
    16381 gggtagcttc aagctgatcc tcaaagcgat acttcaaaat aatctgataa tggtaaagat
    16441 tgtgcgttct tgcaattggc tttggcgttg gccctaatat tctgatctga tcagacaagc
    16501 cctgcttcaa tatggtcagc agttgatagg cctttttgac cacctcttgc tcactcttat
    16561 gcgatagggt cagacctact gtgaaataat agggaggata gcctagcttt cgtcgaatcc
    16621 ccatttcata agcgtaaaag gcttcaaaat cctgcttttt ggccagttga atcgcgtaat
    16681 gctcaggatt gtaggtctga atcaggactt cacctggctt gtctgcacgt cctgcacgtc
    16741 ctgcaacctg agtcagcaat tgaaaggttc gctccgatgc cctaaaatca ggtaaatgca
    16801 aggaagtatc tgcatttaaa acacctacta gggtgacgtt gggaaaatcc aacccctttg
    16861 caatcatttg tgtcccaagc agcacatcag catcaccatt tccaaactgg cttaaaatag
    16921 cctcatggct tcctttttta cgtgtcgtgt ctacgtccat tcgtaatatt ctagcttccg
    16981 gcaacacttg cttgagctca tcataggctt tttgcgtccc tgttccataa tagcgtatgc
    17041 ttttgccttg acagctaggg catagcttcg gaatagccct ttgaaagccg caatagtgac
    17101 aattcatggt tttcgtatcc atgtggaggg ttaaggaaat atcacaattt ggacattgat
    17161 caacatagcc acaatctcga cacatgataa agctagagta gccacgcctg ttgagcatca
    17221 aaacagcctg ctcttttcta gcaagacgct ctttgagttt atcaatcaaa taaggggtga
    17281 agctgctaac ctcctgctga ccaatataat ctcgaaaatc aacaatctca acctgaggca
    17341 tactggcaag aggattggct ctctcagtca gctggataaa ctgatacagt cccttgctgg
    17401 ctctagcgcg actatcaata ctaggggtcg ctgagcccat cactaaggca gccttatggt
    17461 gccttgcacg aatgagagct acatctctgg catggtatct gggattagat tcctgcttgt
    17521 aggtggcctc atgctcctca tcaataataa tggctccaat attttctaaa ggtgaaaaaa
    17581 tagcagagcg agcaccgacc accactctag cctgccctgt cttaattttc tgccattcgt
    17641 caaatttttc tccatctgac aaacctgaat gcataatagc gacctgtctt ccaaagcggg
    17701 aaataaatcg agaggtcatt tgaggcgtga gggagatttc tggcactaag acaatagctg
    17761 tctttccttg ctcaagcaca tgcgcaatca catgaagata gacctctgtc ttgccagagc
    17821 ctgtaatacc ttccagtaaa aagggcttag cctctctgcc aacagccttc gtaatctggt
    17881 caacagcttg ctgctgctgc tgattaagct ttaagagtgg ggctgccttg atgtgattga
    17941 aataatcctc actgcgattg acacgtcgct cctcaagctc gatcagctgg ttggtcacaa
    18001 aatagctaac aacctctcta gaataatcct gataaagctt ggctagctta tctttttgtg
    18061 gattggctaa caaataagcc tttaaggctt ggcgcttttt agcccgattt gaaatcttat
    18121 gctcctgtaa ggctaatcta ttgacctgat agtaagtctc ggttttgatt gtctttttgt
    18181 ccttggctag ataagttgcc ctaatcttac cagactgtat cagcctaagg acacgtccct
    18241 cctgctctgg acttagctta gaataaagca aggaatcccc attagagaaa acatcagcaa
    18301 ggtcagccgc agctaagtca gctgtcgggg tgagcagccg atcgtaatga gaattaagta
    18361 ggctaggaag cattgccttt aagagggtga ttttgtagga aaagactgtt tgtcgtaatt
    18421 gctctgctaa tgccacctgc tcctgattta aaacaggctc agcatctaaa actgaccaaa
    18481 tagccttcaa ttgctgcgtt gattgactag aaaagccaat aacaaagccc tgtagcaacc
    18541 tattgccatt accaaaaggc acatgaacgc gagaaccaat cttaaccaga gataatagct
    18601 catctggaat aagataagaa aagggcttat cggtttgcat caagggaata tcaacaatga
    18661 cctgtgctat gtgttgcatt ttgacttcct ttctatcaag aaatggacct gcaatatgaa
    18721 aaaaactaag attgactcaa ccttagattt tttctccctc ttcttctttt tcttttgcaa
    18781 tctgctcttt tattttacgc tcttcttctt ctcttgctaa acgctctgcc tcaatccttg
    18841 cacgaacagc cgcacgctta gcagcaggat ccgggtgaat cacaacattg cctgactcaa
    18901 tctcctctag tgcctgaagt gttgatttga cagacttaaa ggactgtgtc ggtgcagcac
    18961 ctgcttctaa ttcatgagca cgcttggcct gtaaaataac aagtgaatat tttgatggga
    19021 ctttatctaa taaagtatca attgaaggtt ttaacatcat gggctttact cttttctatt
    19081 tctatcatct gagagatttt gttgttttaa tcatttgatc atagcgacca atcacacgct
    19141 caacgcgaaa atgctcggtc tcaataatac gcttgacacg ctctgcagct aaaggaacct
    19201 cgtcgttgac cacagcataa tcatactctc gcatgagcgc aatctcttcc ttagctcttt
    19261 cgatacgctt ggcaatcacc tcttggctgt ctgttccacg accaaccaaa cggtcctgca
    19321 attcatctaa gtctggcggc gttagaaaaa tgaagacacc atcaggcacc ttagccttga
    19381 cctgcaaagc accctgtacc tcaatttcca aaaagacatc aatgccctta tcaagggttt
    19441 cgttaacata ggttaaggga gtgccatagt aattgccgac atactctgca tattctagca
    19501 tttgaccatt ttttattagc tcttcaaatt cttctcgtgt gcggaagaaa taatcaaccc
    19561 catcaacttc acctggtctc tgtggacgtg tcgtcatcga aacagaatat tcaaatttat
    19621 gatctggcgt tgaaaaaatc tcttgtctca ccgttccctt tccgacacct gaggggccag
    19681 agaaaacgat taacaaaccg cgttcagaca ttgtgttctc cttattgatt gctttctaat
    19741 agtttatcaa aaaggctatc gtttttcaag acaattatca gcccaatcct aagaaagaaa
    19801 aggaagagat agacgccttc tcaaagctag aggctaaact ctggcttttg aaaagcatac
    19861 actctttcct ttttatttcg cataatctat tgctcgcaac tcacgaataa cagttacctt
    19921 gatatttcct gggtaatcca agttattttc aatcttttct cttaccttgt gtgagagaac
    19981 cacaatctcg tcatcagaaa tcttttctgg ctgaaccatg atgcgaatct cacgaccggc
    20041 ttggagggca aagctacttt gaacaccatc aaagcttgtt gcgatttctt caaggtcacg
    20101 aagacgcttg atatagtttt ccacagattc attgcgggca cctggacgag cagagctaag
    20161 ggcatcagca gcagctacca gaactgcaat aaccgaatcc ggctcgacat cgccatgatg
    20221 gctggctatg gtgttcacaa caacagggtg ctccttgtac ttgcgagcaa actccatacc
    20281 aatctcaacg tggcttcctt caacctcacg atcaatagcc ttgcccatat catgcaagaa
    20341 acctgcgcga cgtgcaagtg ccacattttc accaagctcg ccagctaaaa taccagctag
    20401 cttaccaacc tcgactgagt ggcgtaaaac attttgacca aatgaggtac gaaactgtaa
    20461 gcgccccatg atcttaatca aatccgggtg gaggttaggt gcaccgatct cataggcagc
    20521 agcctcacca tactcacgaa tcctattgtc catctcaaga cgatttttct caaccaattc
    20581 ctcgatacgc gccgggtgaa tacgaccatc agcaatcaag gactctaggg tcatacgagc
    20641 aatctctcga cgaatagggt caaagcctga taaaacaacc acttccgggg tatcgtcaat
    20701 gatcacatca atccctgtca gactctctag agtacggata ttgcgaccct ctcgaccgat
    20761 aatacgccct ttcatgttat catcaggcaa gtgcacactt gtaatcgtct gctcagtcac
    20821 atactcacca gccatacgtt gcatggcctg tgctaacagg tccttagcag tcttgtctgt
    20881 cctgtccttg atgtcacgct ctgcatcacg aatgcgtgtt gcgatctcat gcgtcagctt
    20941 gttttcagtt tccatcagga taacctcacg cgcttctgca atggtcatag cagcaactcg
    21001 ttggagctct gctcttttgt cttcctcaag tttttcaacc tgtgcctgtc gctcatcaat
    21061 gtgcttagat ttatcggtca gactttgctc tttgctatct agtacttttt ctttacttga
    21121 tagattttca tccttacgat caagagttag agcacgctct gccaagcgcg tctccagctg
    21181 tttaagctct tgtctttcag atttaaattc ctgttcaatt tcttcacgat actttcttgc
    21241 ctcttccttt gcttctaaaa gtaattcttt acgacttgct ttactttcac gttgtgctgt
    21301 ctttttgata tgagcggcat cggcctttgc cttgccacga atatcaacag catcctgttc
    21361 agcgtttaaa agagtcaact ctgcagcttc cttcgcagac ttgagtctaa tcgaaataag
    21421 tgcataacct aatattacac caatgaggcc acagacaagt aacgttatga tattaattaa
    21481 catgtcttta cctcaataat agtttagttt tcattaacag aaagccatct cttagtctat
    21541 cataaaatga agatttagac aatttaaaat ccacctacat ttttctaaaa tctagtgatt
    21601 ttatgttatg atattgataa aaataaaaag gagtttctta tgccaaaaga agttattgtt
    21661 gaaagctttg agcttgatca tactattgtt aaggcaccct atgtacggct aatctccgag
    21721 gaatttgggc cccagggaga tgtgattaca aattttgatg ttcgacttgt tcagcctaat
    21781 caggctgcca ttgagactgc cggtttacat accattgagc atttattagc caagctcatt
    21841 cgtcaacgca ttgatggaat gattgattgc tccccctttg gctgccgcac aggctttcac
    21901 ctcatcatgt ggggcaagca tagctcaaca gatattgcta agatcatcac gtccagccta
    21961 gaggaaattg ctacaagcat cacttgggag gacgttcctg gcacaaccat tgaatcctgc
    22021 ggcaattata aggatcacag cctttttgct gctaaggaat gggcacagct tattctcaag
    22081 caagggatct ctgatgatcc atttaaccgc catgtcacct cataaaacga aagcctctct
    22141 tttctgctaa tgtgaaggag gcttttaatg tattcaaaaa ggtgccaaag gcaaggctca
    22201 atgcccttac ctttagcacc tgtgataact agagtatcca gttcaggatc acaccttgtc
    22261 ttctaagcat taatagtcta agtcctctgc atgccccttg ccatttccga caaaatagcc
    22321 tgttttgcaa ttcaatgaaa agaggtaggt gccatcaggc ttaaacatgt tgtaatagcc
    22381 attcccattg ataatattga ccggctctag gatataatca ttgcctgaaa tatagcccct
    22441 tgcttgtgag gtagccacaa tacgctcaag cacacctgga ttaaaggccc aagcagggtt
    22501 tcctgtatca gcaatcatag cctgattgta gggcacacga gacaggtcac gctgcaatat
    22561 tgaagggtca tagcctgtaa tgccatacat tggagccact ggagctggta cagcaggaac
    22621 ctccggagct gcagggcttg ctggtaaggc agaagcagct ggagtgctag ctgcttgggt
    22681 agcagacctg cttgctagct gctcacgacc tgccttgatg cttgattgta gcaatgaatc
    22741 aagttttgca ttaccagtgg ttagcgtatc actagctagg tcatcaaaat tagcatcagc
    22801 tttgacctca gctgcaatct tttcaccatt gacaattgca gctgttgtaa atttcccatt
    22861 aaccgcctga atagctgtta cttgcttttt cagcccagta accttttcct tagccttgtc
    22921 ataataggct gtcccttcaa gcctttttaa agcagtctcc aaattcggta actgatcaaa
    22981 ggcgctattt tttagggttg ttttatcatt atctgtgaaa aatgtcttgt aaagatcttc
    23041 aaaagcctta gcattagcct ttgttttgtt ggtctgatta gctgttgatg ctttgctcct
    23101 tgctttttta gaaacagtag cctttgactg aggcttatgc ttagacagct gatagatatg
    23161 gttgagggca aaggctgagg ctacaagggt tagcgtggct aacaaaatag caaacagagg
    23221 ctttttcttt ttagacctac gactagcata gctatctgat aaaatactct ctacttctgc
    23281 aggtcgctcg ctaactgcgt catcagctag ctgcccagta aaatcactag cagaatcagt
    23341 agctgccgct gaagtgtcag ctctagctgc tagaggctca atgaatgagg tctcaccggc
    23401 tggcttctcc tctgttgaag cctcgtccac tggctcaaca tcaactaagc cggctttgct
    23461 gagctcctct ctttgttttt tgataaagtt atccagactt gctgtatcta actccatata
    23521 ctttgcatca aacttttgtg atgacacttc gttacgatgc cgcttaatat atttgtctaa
    23581 aacactatca tcctcggtaa tccctgcttt tagctctgag tccttgcgta ctgcctcacc
    23641 gattgtcatt tttttggctt catgaagctc caaattttgg ctttctgcct ctgattcaaa
    23701 tgctttgctt ttttctgaca cgttttttac ctctctatat cagattgcgc tttaccctct
    23761 ctccataaaa ttgatacaaa tcaaccctta gagtaccatt ataaagctta cgttttttat
    23821 cagctttttg accatatttt tgttcaaaat gatcatcact cgtcaaaata aacttgctcc
    23881 aggtaactaa tggagcaaag acctgtacca tctcattata caagatgtct actgctttgt
    23941 catcaagcaa acgctctcca taaggaggat ttgaaatgat gacaccgttt atcttgtctg
    24001 tacggaaatc ctgcaagcgc atttgcttaa aggtaatgat atcagccaag ccagcctcct
    24061 cagcatttct cttggcaagc tcaaccatac gaccgtcaat atcaaagcct gaaatatcca
    24121 gctcaatatc ataattagcc tctttttcag cagcgtcacg aaccttttga acacgatctt
    24181 tgtccaccca gctccattcc tcaaaggcaa aggagcgatt aaagccagga gcgatattca
    24241 ttccgatgag agccgcctcg atacaaaagg tccccgatcc acaggtggga tcaaccaagg
    24301 gcttatccgg aaaccaatta gacagcttga ggatagctgc tgccatgttt tccttaatag
    24361 gagctccccc tttttccacc cggtagccac gcttaaatag gcttgagcca ctagtatcaa
    24421 tcatcagggt agcctgatcc tttaagattg agacctcaat tttgaactca gcccccacct
    24481 cttgaagggg aatatgctcc ggtctatgaa aatgctgctg caattttctg acaatggctt
    24541 ttttggtaat ggcttgaaca cttggctcgt tgtgcagggt tgacctgaca cacttagcct
    24601 ttgcaatagg aaacctagca cctaagggca aataatgctc ccaatccaag gcaaatacgc
    24661 cctgaaacag ctcctcaaag cttcgtgctg ggaactgacc tacaataatc ttaatacggt
    24721 cagccgctcg cagccaaaga tttgctttag caatagcttc aatatcgcct tcaaagaaga
    24781 ccttgccatt atctactcgg cagtcaaatc ccaaggccct taattcctta cccacaacag
    24841 cctctaggcc agctgctgca gttgctacta atgtaaattg ttctttcata tgactctttc
    24901 tatcctaacc aaataaaagc tagcatatgc tagcttaacc tattatgcaa ttttctataa
    24961 gccatgtttt gttccagaaa taactaggta ttatctcctt cgataatcat ctgtctactg
    25021 tttgtcaaca gtcaggatag cttgttcgtt tccaactatc ccatgcccct accaaagttt
    25081 gggttgctag cttgaggggt ttaccgcgtt ccacttttta cgtttccata aaaacttcgt
    25141 cactgtggca ctttcagagc tactctggca tatcaaggac ttagcctttt cactcgccgt
    25201 aatgtgtcaa acacatccct aggcttattt gttcgcctag cacaaacact accagcatca
    25261 cagccggtgc tagcatggac tttcctcata gtattgcaat actacgcgat tatccaaaaa
    25321 ttgcacatct acattactca ataatttgct ttccaaaaac ctctttttcc agcttgctaa
    25381 tgcgctttag catgtcaaaa ttggtggctg actgtgctac tctggttggc tgtgataccg
    25441 cctgagagct gcctgctaaa ggatcacgca cctgagcctt agcctttttt aaggcttcat
    25501 tttcagcctt tagggcctcg atctgagcat tgaaatactc ataatccttg atgacgttat
    25561 caaggaattc gtcgacctcc ttcttatcaa agccacgcat actggtctta aattcttgct
    25621 caaaaatgtc ctttggacta taaattatac ctgtcattct atactctcca aacggtcaat
    25681 ctttttcaaa tatcaaactt tgatatcact acttatggta cagaaaaata aattaaaaag
    25741 caagtattta aataccagtg atttttaaat atcactagct actcatctgc aatgtcattt
    25801 aaacgctcaa agtttaggaa agaaaggggg taacagggct gctccttcat agctgctacc
    25861 aaatagctta ggcgcgtttc gtgctcacta tcataaaaaa gataggctcc gtctgtattg
    25921 tgaatcaaaa agtgatggta gctctttagc tgtttagggc tttcatagct gggatagcta
    25981 tatttgacaa aatcagtctc ccgaaattgc tgcagctgct gctgattgcg atcattccaa
    26041 gtgctgccat gcgtttcaaa ggcaaaaata gtcgctgtct ttaaggggta ggtctttttg
    26101 aggtcattag ctacctctaa agcccactgc tcaaacccta aattcccagt aaaaataaac
    26161 cagtctaccc cctcctcaag ataagcaatc agatctcttt ctatcgcttt tttgataatg
    26221 gcaactcttt tatccttttc actaaagatg cccagctcaa aacttcgata gcctgttacg
    26281 agaattgcag tcattagatg ttatcctttc aaaaatatgt tataatgtga atgcttaaat
    26341 tattattaag tcatgatgtt aggagaacaa tggttaacta ccctcataat cctattcgcc
    26401 aaaaggtgac ccctcttcaa aagcagcaaa agcacaagca agtagacttt gctaatcgtg
    26461 gtatgtcctt tgaagcatcc attaatgcaa ccaacgctta ttacttggcc aagggcattg
    26521 ctgtcattca taaaaagcca actccgatac agattgtcaa ggtagactat ccaagacgta
    26581 gtcgagccaa gattgttgag gcttatttta agcaggcttc aacgaccgac tattctggta
    26641 tctacaaagg gcattatatt gattttgaag ctaaggaaac aagacaaaaa acagctatgc
    26701 caatgaaaaa ctttcacgcg catcagattg agcacatggc tgctgtttta aagcaaaaag
    26761 gcatttgctt tgtcctcctt cactttgcga cactaaagga aacctattat ctacctgcca
    26821 aagcactcat tgatttttat cagattgata ggggcaacaa atcaatgcca cttgattata
    26881 tcagaaaaaa cggctttgag gtcaagctgg gagcatttcc acaggttcct tatttagata
    26941 ttatagaaca aaaattttta ggcggtgatt acaattaaca atccaaaaat ccttaaattc
    27001 ctgaagtata cattaggtgc tatccttagc cttatcattg tgacaattac cttaggtggc
    27061 cttttgtttg cttactatat cagcagtgcc cctaagcttt ctgaggccca gctcaaatcg
    27121 accaattcca gtcttgttta tgacggtaat aatcatttga ttgctgactt gggctctgaa
    27181 aagcgtgaaa atgttacagc tgacagcatt cctattaatc tggtcaatgc tattatttct
    27241 atagaagaca aacgcttttt taatcatcgg ggggttgatc tctatcgtat cttaggtgca
    27301 gcctttcaca atttaacaag caaaacaacc caaggggggt ctacacttga tcagcagctg
    27361 attaagctag cctacttctc gacaaacgag tctgaccaga ccttgaagcg aaaagctcag
    27421 gaggtttggc tggcccttca aatggagcga aaatatacca agcaagaaat cctgaccttc
    27481 tacatcaaca aggtttatat gggaaatggt aattatggta tgctgacagc agccaaggct
    27541 tattatggca aggatttgaa agatttgtcc tatgctcagc tagccttgct ggcagggatt
    27601 ccacaggccc caagccagta tgacccctac acacagcctg agacagctca aagccgccga
    27661 aatattgtcc ttcagcaaat gtatgctgaa aagaacatta ccaaggctga gtacgaagca
    27721 gctatcgcca cacctatatc agaaggccta cagcctctcc agcaacgcgc cagctatcca
    27781 aaatatatgg ataattactt aaaacaggtg atcgagcagg taaaggctga gaccaacaag
    27841 gatatcttta cctctggtct aaaggtttac acaaacatca ttccagaggc tcaaaaaaaa
    27901 ctttatgaca tttacaattc tgaggactat gtgtattacc ctgatgctga ctttcaggtt
    27961 gcctcaaccg ttattgatgt cacaaatgga cacgttatcg cccaattagg aggacgcaat
    28021 caggatacca acgtttcctt tggaaccaat caggctgtct taaccgatcg tgactgggga
    28081 tccaccatga agccgatcac agactatgga cctgccattg agtccggtgc ttacaattct
    28141 acagctcaaa caactaacga ctctgtctac tattggccgg ggacacacac tcagctctat
    28201 aactgggacc ggagatacta tggttggatg accattcaag ctgctctcat gcaatcacga
    28261 aacgtccctg cagttagggc tctagaggcg gcaggtctta gctatgcaca gtccttcctc
    28321 agtgatctag gcattaatta tccagagatg cattattcaa acgccatctc aagtaacaat
    28381 agcagttctg attcaaaata cggtgcaagc agtgaaaaaa tggctgctgc ctatgcagct
    28441 tttgccaacg gtggactcta ttacaagcca caatacgtca ataaaattga attcagcgat
    28501 gggaccagca aggtcatcga aaataagggc aagcgtgcca tgaaagaaac aacagcctat
    28561 atgatgactg atatgctaaa aacggtacta acctacggta caggtactgc tgctgctatc
    28621 ccaggagttg cacaggctgg taaaactggt acctcaaact ataccgatga ggagctggca
    28681 caaattgttg agacacatgg actatctcct gattacgtgg gaacaatggc gccagatgaa
    28741 aactttgtcg gctacaccaa ccgatacgct atggcggttt ggactggtta taaaaaccgt
    28801 atgacgccaa tttatggcta cagcctagaa attgcttctc atgtttatcg caacatgatc
    28861 agctatctca ccggcggcta cagcgacgat tggaccatgc caagtgggct ctatcgtagc
    28921 ggcggcttcc tctacctaag tggtacctat acaaacagta gcgattatac aagctctgtc
    28981 tacaacaacc tctatggtaa taacagctca gcttcaagcc aatcctcaga tgaggataca
    29041 actgaagaca gccactcaga agcaaacgac agcacaacgt catcatcaga gcagcaatca
    29101 agctccaccg atgataagaa aaccaactga taacaaaaaa ctggttcaaa tgttctgaac
    29161 cagttttttc aattatttgg ctaaggcacc catcggatcc caaggggcaa gtacctgtgg
    29221 ttctgcctca taggctgcta attcatcagc tgttagtagg tccttgcgaa caacaatctg
    29281 gtaagtatac tcgtccatcc aagcatcaga agcaacaaag tatcctttgt caccaacctt
    29341 gtctccccaa gaattttcaa ccttccattt gataggctta ccagtatcat ctaaatcaac
    29401 acctgtcaaa accatagcat gtgtcattaa gctttcgctg taatcaaggc gaccagcctt
    29461 gtcttggctc aactgaatat ccatacctgc ctgaaaatca taggtattaa gggctagaat
    29521 ccccttttga cgatctgata cctgaccaac gtctgaacca aaccaaacgg actctccagc
    29581 ctgcatttgc ttaatagcaa gctccttgaa gcgctccata tcaagattaa ggtagcgcac
    29641 ctcaggactg ccaacaacat taccaagcat atcaaccgta taagatttgc cataaggctt
    29701 atcagctgtt ggggcgttga taacagacac ataatcagac agctttagac caacatattt
    29761 ttcataaaat gcctgtggtg tgatgccctt atcagcatga tagtgattat ccttatcacg
    29821 ataagcaaaa tcaaattgac gaggtggcaa accaagattc atggctaaga aattaaagat
    29881 ttcctgaagt agctcttctt ttttagcctg tactgcctga tgatcagcac cagcactgat
    29941 cacatctcga agaatctgag cgtcctgacg caagagctta ttgaggtatt gatttagctc
    30001 acgactattg cttgatgaca cagactctgg gtagactgat tttggcacaa caccgtattt
    30061 ttcaaacagg gctacaacca tgtcccactg accaccgtct tgctgcggaa cgtccaaaag
    30121 aaacttaacc ctacggctag tcaaggcttg atcagcagtt gcaatcacct gttccataaa
    30181 ccagtttgat ttttcgtatt tgtcccagaa aaaggtgtgt gcttgtgaca actcaaaatc
    30241 ttctaattta aattctgaaa taagcttatg gcgaaaggtg tttaaggctg caaacatcca
    30301 gcaacgacct gaagcctttt gattagagac cttatccttt gtcaagtcaa tggaaaagac
    30361 aaaatcattg tcgatctcac tttgtcttgt ctccaaggat ttaagcaagc cattgtgagt
    30421 gatggcattt tcaagagcta aatatttagc attagcttca taattagcat atagctgttc
    30481 tgtaaatgtc tctgttaata ctgacatcat tttcctccaa agataataaa taacaacacc
    30541 taaaaataaa gttgacagaa aaatccataa atactgtcaa tttcattttc aaggattact
    30601 tctattatag accttatttg atattcttca agtaaaaaaa ttaggctaac ttaatttttt
    30661 aaagctaagc agcagctttc caataaccag acaaaaagcc atctcaaaag acgacaaaac
    30721 ctgctggact ttgagcacct aaacatgtca tatgtccacc tcagcatgaa ctcaaagaag
    30781 ctagctgtgt ctggctatga cttcagttta atcattagct tgccttagcc acaaaaagaa
    30841 tcgtctccac tgtagcaaaa gtgcttgata taacaccatc ggctaagtca aggggcccct
    30901 gatagttaac tgaaacatat ggcaaagcta aaaccaaaga cttcttctcc ttaaagcctc
    30961 tggtttttag ttagctgagc attctccttt atcttggctg ctttaagata gggacaaatc
    31021 aacaactacc ccaatcccat ttacaaaaaa gccctaagtc agagccttca tagggctaag
    31081 ggtgagggaa gctcttaggc aacagctact ggatttatgc ctaatagaag ctcctgtccc
    31141 tcctcaccta tttaaaatag cattggttta tctatagcct gtgtaggttt gaggatcact
    31201 tccaaaagtc atcaaaaata gtaattggca gatggcgctt gtgctgccct ttatgccacc
    31261 agtcttcaat ccttgcctga gcttcagcgg aaatcgtatg cccctctaag taatcgtcta
    31321 tctcttgata agtaacacct aatgctacct catctgcaag tcctggcttc ttatcctcta
    31381 gatctgctgt tggcaccttc tcatagaggc tggggtcagc ctttagcacc tttaacaagg
    31441 ccttaccctg ccgcttagtc aagcgaaaaa ggggtagaat atccgctccg ccatcaccaa
    31501 acttagtgaa aaagcccgta acattttcgg cggcatgatc tgtcccaatg acagcaccag
    31561 ctgtttgacc agcgatagca tactgactaa tcatacgctg acgtgcctta atgtttccct
    31621 tattaaagtc agaaatctca agccctgccg cctctaaggc tcttagctga ccatcaacag
    31681 cctctttaat attaaccgtc aaggcttgat caggttgaat aaatgctaag gctttttgtg
    31741 catctgcctc atctgcctga acaccatagg gcaagcggac agcgataaat tggtactgct
    31801 catcacctgt ttcagcgcgc agctcttcaa tcgccatctg agctagcttt ccggctaagc
    31861 tggaatcctg accaccagaa atccctaaga cataagtctt taaaaaaggg tgctttaaca
    31921 aataagcctt taaaaaatca accgactggc gaatctcctg cttaggatca attactgctt
    31981 tgacctcaag ctgacgaatg atatcctctt gtaatgtcat atcaaatcac tccttttaca
    32041 ggcttccttg cggattttgt caataagatg catcttattt tgccaaacat caagcgcaag
    32101 atccacaggg taatgctgcg gattcaagac acgcttatat tcgtcccaaa gcttatcaaa
    32161 ttcctttcta gcataagcct tgatgtcttt taagcttggc agctgataaa cgagctttcc
    32221 tttatcaaaa atatctacta gcaaaggaac agcatcaaaa tctctgacgg ttttattaat
    32281 gtaggtataa gtcgggtgga acatgtgaat ttcctctagg tcattgacat taacacctgt
    32341 aaaggtgatg taatcgcctt ctgacttgcc cttttcgcgg ctggtaattc gccaaacctg
    32401 ctttttacct ggtgttgata ccttttctgc attatttgat agcttgatag tatcgcgcat
    32461 ggtaccatct gcctgctcta tcgaaacaat cttataaacc gctcccagag ctggttgatc
    32521 ataggctgta atcaattttg ttccaacacc ccaaacgtca attttagctt tttgcatttt
    32581 caggttgaga attgtatttt catctaaatc attggaagcg taaatcttag cctctgtgaa
    32641 gccggcagca tccagctgct ggcgtaccct tttagatagg taagcaaggt caccagaatc
    32701 cagacgaaca cccaagaaat taatcttatc acctaattcc ttggccacac gaatagctgt
    32761 tgggacacct accctcaagg tatcataggt atcaaccaag aaaatacaat ccttgtgcac
    32821 actggcatag gccttgaaag catcataatc attaccatag gcctgtacca gagcatgtgc
    32881 atgcgtgcca gacacaggaa tgtcaaaacg ctttccggca cgaacgttac tagttgcgtc
    32941 tgctccgcca ataatggcag cacgtgtccc ccaaacagca gcgtccatct cctgagcgcg
    33001 gcgtgtccca aactctaaaa gtggctcatc ttcaataaca gagcgaatac gagctgcctt
    33061 tgtagcaatc aaggtttgga aattcacgat attcaaaaga gctgtttcta ctagctgaca
    33121 ttgacctaaa ggtccctcaa cctgaacaat aggctcattg gcaaagacca agtctccctc
    33181 ttgtgctgag cgaatcgtta gctctaaacg aagctctctg agataggtca aaaaagcagg
    33241 gctgtagcct agctccttca aataagccaa atcggtctca gaaaaggtca attgctcaag
    33301 gtattctacg attcgttgta gaccagcaaa aactgcatag ccattgttaa aaggctctct
    33361 acgaaaataa acctcaaaga cagcattacg attatgaatg ccctgctcaa aataaacctg
    33421 catcatattt aattgatata aatcagtatg aagggttaag ctatcatctc tgtacatata
    33481 agtaactcct taacataatt gttattatta taccatattt ttggcataga cctgtaagat
    33541 tcaactaaaa tcctctgctc aagctttcta aaaaagaagc cttgagctgc tattaagcct
    33601 gacatatttt ttgccagtac cttcctaaaa agtctatagc acaagggctt atggcttttt
    33661 aacaaaagca gtttcagttg atagcattca taaaaaaaga ttgaagaaat tgaccaaaat
    33721 agcccctttc ttcaatctat ttaactcaca ccttagcctt ttaacgcttt tttacacttg
    33781 agctgactgt agcagccaaa gactagaatc caaatgctag caccaattgc cccgatatag
    33841 gtggacttct gtaaaaacag tgaaataaaa acaaaggcaa aaaaggctag ggtcaatggt
    33901 gttgttagct gataacttgg catcaaataa ccatctggca taaagtcact ggactgacga
    33961 tatttccaat gcgcaagcat ggtcaaagca taaatcgcaa tataaacacc agatgatgag
    34021 gccgtaatca gcgaaaaggc atctgcaaca ccgggcagga tattaatcaa ggccgacacc
    34081 ccaacagcaa cagcagaagc aataatagcc ctacttggta ccccttgacg agatagggtg
    34141 ttaatcctca aggctttagt aagagcattt ggggtctcat tagcgatttg atacaaatgc
    34201 cgacctgtcg aatacagggt cgaatttagg gctgatgctg ctgatgttaa gaccacaaaa
    34261 ttaattaaag cagcagccca tttaatccca atcagcttaa agaccatcac aaagggagac
    34321 tcgtccgtag gcaactgata ccaaggcaca atcgccataa tagacaccaa agcaccaacg
    34381 taaaaaatga caatccgcat cggaatctct tggatggcct tgggcaagac ctttctagga
    34441 tttgcggtct ctgaggttgt aataccaaca aattcgatgg cctgataggc aaagaaaacc
    34501 atctgaaagg ccatgaaaaa tttcaacttc ccattcggaa atagtgaaaa atgatccaca
    34561 atattggcaa ggctggcatg accgacatgc gtttcaaagc ccgttagaac cataaaaacg
    34621 gctgttgcaa tcaaggctaa aatcgcaaca atcttaatca tggcaaacca aaattcagtc
    34681 tctccaaaga cccgcacagc aattaaattg atggagctaa gcaacaccaa aaaaacgagc
    34741 tgaatcagcc aagatggcca agcaggaaac caaaactgaa cataggaggc gacagctgta
    34801 atctctgcca tgccaataaa gatcagggaa atccagtaag aaagcccaga aaaatagccc
    34861 cagcctggcc caatatattt tgtaatgaaa ttgataaagg tatgctgatc cggatcatag
    34921 tatagcatct caccaatagc ccgcatcatc aaaaacataa agacacctgt aatcatgtaa
    34981 acaaagataa tagacggacc cgttaaggca atagaacgac cagctcctag aaagagacct
    35041 gttccaatag tgcctgctat cgcaatgagc tgaacatgtc ggttttgcag cccccttacc
    35101 atgccattct caagttcttt agtgctttta gcttcttttg tagacatttg actctccatt
    35161 caattaaaaa aacaccacta ttatatctgt ttttcagaaa atgttcaact ttctctaagg
    35221 cttgcaaact aaaaaggcca accaagcctt tttagcgtta acctttttaa gatgataggc
    35281 tttcaatgta atggtagacg ccttgaccgg caatggcacc atctccaact gctgttgtga
    35341 tctgacgcag ctgcttttga cgaacatcac cgacagcaaa aataccagga atacttgtct
    35401 tcatttgatc gtctgtcaca atccagccct cttgattggt aatgcctagc tcagatacca
    35461 tttgagtaac cggaatcaag ccgacataga taaagacacc accaaagtca tggctagtca
    35521 cttgacctgt tttgacattt tcaatcacaa cattagagac cttaatatcg tttccttgaa
    35581 tctccttgac aacagaatcc cagataaaat caagcttttc gttggcaaaa gcacgctcct
    35641 gcaagatctt ttgggcacgc agctgatcac gacgatgcac aatcgttact ttcttagcga
    35701 actgggtcag gtagatggct tcctcaactg ctgaatctcc tcctcctaca actaataact
    35761 cctgattgcg aaagaaagca ccatcacaga ccgcacaata agaaacacct cgactggtgt
    35821 actcctcttc tccagcaaca cctaaaagac gatgctttgc tcctgtcgcg acaatcactg
    35881 ttttagtatc gtagtgcgta tcttctgtgt acacacgctt ataatcacca caatcctcaa
    35941 ccctttgaac aatgccataa atgttttcaa ccttaaattt ttcaagcggc tcatacatct
    36001 ttaacgatag ctctggtcct gaaatgtgat catagccagg ataattttca atatctgatg
    36061 tgttattcat ttgaccgcca ggtgccccct gctcaataat gccaactcgt aggttactac
    36121 gtgctgcata taaagcagct gtcataccag caggtcctga tccaataatg agtgtatcgt
    36181 acatgggtta actcctctta atagtcttgt catcatttta acaatagcta catcgtattg
    36241 caattatttc gccttcaata ccaccagaat gctcataaag gcaaaggaca aaatcggaat
    36301 cgtcaaaata gcaaccataa tcatctcata taaaaatgcc tgtctctgga gaatggtttt
    36361 atcctttttg gtcacagcac gccataaaat ccacaaaaga caaagcatga ccatcgtaat
    36421 agctgctaac aacagacctt ccaaataaaa gcgaaaaatt tctactaaca tctttatcta
    36481 cctgattacc ataacctttt ttcatggcag cttagctttt aagcacatac aagaaaagcc
    36541 tagcctacct agaccttttt attatatcaa aagccggctt ttaaatatac gtttttgcat
    36601 agtttgcaaa aaattccttt gttcttgctt ccttagggtg tctaaagatc tgctcaggag
    36661 ctccctcttc aagaattttc cccttgtcta aaaaaagcac cctatctgca acctgataaa
    36721 caaaagccat atcatgactc actaaaatca tcgtttgacc tgccttggca gcatcaataa
    36781 tagaccgttc aacctctcca accagctcag gatccaaggc tgaggtaggc tcatctaata
    36841 atagcacatc tggcttcatg gctaaagcac gcgcaatagc aaccctttgc ttttgaccgc
    36901 cagataaatg acgagggtaa tggttttcac gatcagacaa gccaacctta gctaattctg
    36961 ctctagctat gtctgttgct tcttggtcag acagtttttt aactattttt aatccttcct
    37021 tgacattgtc aagcgctgtg cggcgttcaa agaggttaaa ttgctgaaag accatcgcta
    37081 attttcgtct aagcgttaga atgtcttctt ttgtgatgtg ttcaaagtca actgcaaagt
    37141 catcaatcgt aatacttcct gtatctggct gttcaagata attcatgctt ctaaggaagg
    37201 ttgattttcc tgcacctgat gcaccaacca gagctataac ctgccctttt tcaatcgtca
    37261 ccgttaaatc gtctaagatc ttttgtccag agaaggactt ggttaaatga gttaccttaa
    37321 tcattagcgc aattctccta tcttgctatt atttgttggg attggtgctt tgatagccat
    37381 gttatattca attaggcgac cagcctgttc tatcaaaata ctaatgcccc aataaactaa
    37441 ggcaactgag atgtaacgtt caaaataacg ataatctgct ccccctagaa tctgtgcctg
    37501 tgcaaacatt tcaacgatac ctgcattgaa ggccagagag gttccctttg tcaggcctat
    37561 caacccatta atcaaggtcg gtgttgccac aacagcggca tttggaatga taactcggcg
    37621 ataaacctga gcagaggtca ttcctaggct cttagcagcc tcaatttcgc ctgtgtgaac
    37681 agattgaatc gcagctctaa tggtttcact cgtataagca gcttcattga aggcaaaggc
    37741 ggtaatcgca aagatagaag ccggaatagc gttgatattc caatcaaagc catagcgttg
    37801 atttaagaat ttcagaaaaa gaggaatacc atagtagctc agcattagct gaaccaatat
    37861 gggggttcca cgcaaaaagc taacaaaaac cgcttgaatc ggataaagaa tgcgaaccct
    37921 gttgattttg acaatggcaa aaaccaaggc caaaaaaaga cccaaggcag caccagctat
    37981 cgtcaaacca agtgtgattg gcagacgcct gataatatct ggaatggcat caaaaacagc
    38041 atgccagcta aacagcttcc cttctgggat caacgagatg agcttgtcat accaagccca
    38101 cccacttgtt aaaaacgtag atgtcatgta tcgccccttt atactggttt gtctcaatat
    38161 tttcatttta acattcttga gatgtcatgt aaaatagtaa atccgcatga taatgataag
    38221 aaaagcctat cgcagaggat aggactcaaa caaaggaaaa aaactctttg aaataccgtt
    38281 aacagtagcc tcttggagct accaagcttg aacttgagcc gaactctcaa agcctccaag
    38341 tggctaattc tcaaagaata tagccactgg tacaagacta acaatcagct actaggccaa
    38401 aaaggtcaaa agcttggcta gctggcacag ctaactgcct caaaggctag gtcaacgaaa
    38461 gattgaagcc tgcccagggc ttgagggctt ttagccctgt caattaattg accttggaga
    38521 taaagtctcc tcccaaaaat gcttggctga gctttctgag ctgacctgat tttttaagct
    38581 tagccagcct tttgttgaca aagctctgta gagccttacc cttttgatca ttggcaaaca
    38641 cataatattc caagccatcc ttagcagtat cagcctgctc cttgagcttt gtcacatgca
    38701 catcaaagcc ttgctcctca gctacggttg ttagagaaat agcgtcatag aaaagaaagt
    38761 ccagttgacc attctccagc agctgcagcc tttgagtaaa tggggttgac tcagaagcat
    38821 aggtaaggtg aataggcttt tggtcaggat gggattggtt ccatttttca aggataagca
    38881 tgtaattgga gccagctatt ccttgggttt tctttccaga aagatcagct aagcttttat
    38941 actgctgctt accctttgtt gccagagcat aatgcgaggc cgaaataggg cttgaaaaca
    39001 aatacttttc agctctttcc ttactatagc caaaattatt ggccccaatc tgataacgac
    39061 ctgcatcaat accagccagg atcgatggaa aaggaaccac ctctatgctt aaccgatact
    39121 ttttggagcc tttaaaaacc ctttttagaa cctcaatatc atagcctgta acgctatgct
    39181 tcttcctata ggtaaagggc ttagtggcag catctgttgc tactctgatc acctcttttt
    39241 gacgagctgt gacctcatgg ctagtcacga ctgccaagag tcctagactt gctagcaaaa
    39301 aaaagagtgc tcgctgtaat tgttttgtca taccatactc ctatctctta tacagtagcc
    39361 attttaacaa aaaatgataa atttgaataa tatcatttct ctatcaaggc aataagaaaa
    39421 tagtatcaaa caagcaatta aaacagcaca ttcttcattt acctgatcat ggattaacca
    39481 caacagacaa gctttagcta ttagcaggct gcctaagcca aaatcaacac ctcaagcttt
    39541 caactgactg atgtaaaagc tagtagtcac ctctacaaga agaaaaagaa ctgtttgtgt
    39601 cattcaacca gtagcaccct tcttaactgg tcattcctat ccagctctac tactaggctg
    39661 tcagttaacg atcagaaaaa aagttgacct atctgcctta tgaagcctag aaaactagct
    39721 ttcattctgt ttaacattag aaaacgagta aatagtttaa aataaatttt ta
//
LOCUS       DARYNN010000015        39094 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.015, whole genome shotgun sequence.
ACCESSION   DARYNN010000015 DARYNN010000000
VERSION     DARYNN010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39094)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39094)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39094
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.015"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(93..464)
                     /locus_tag="TVB59_000723"
     CDS             complement(93..464)
                     /locus_tag="TVB59_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009649.1"
                     /translation="MKLRRKTRLTKIGAPMTVNIGKSHKVKLYPGESIDIDLPDAEDY
                     LTIKHSRQAKKIVTNQDQVTITDNPINLILFWSGVVLVLGSHLVLSFDSSWLYWLTII
                     GLSSIIVSYLVPRFKWVVTQS"
     gene            683..1321
                     /locus_tag="TVB59_000724"
     CDS             683..1321
                     /locus_tag="TVB59_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEL1009650.1"
                     /translation="MVKGIIFDMDGVLFDTEPFYLKRREAFLTSKGIRIDHLSPEDFI
                     GGNLQQIWDKVLAGQANADEARDIAVAYEAYKLCHKPPYQELMFKGVKSCLKALKGQG
                     LKLALASNSSRCDILLALESSHIKAYFDLTLAREDVTAGKPNPEIYNKVAQALGLAKA
                     EFVVVEDSQKGIAAAKAAGLKVLAIKDKRYGIDQGQADKRIDSLRQLCELLR"
     gene            1517..2053
                     /locus_tag="TVB59_000725"
     CDS             1517..2053
                     /locus_tag="TVB59_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1009651.1"
                     /translation="MLSLLIGGLMAVKLLTERLIIQELNETYFEPYHKAFTEEITAFQ
                     WPDPFKDIAAAKETLASFIAEMKKGNMLELVILNKANDFVGSLEVFSLDSETPELGIW
                     LKKSSQGLGYGYEALRAIVDYLKGKNKYRYFNYEVDVRNTGNIKLVEKFNVVTSTYQE
                     CETASKKRLCLQVYHILN"
     gene            2916..3320
                     /locus_tag="TVB59_000726"
     CDS             2916..3320
                     /locus_tag="TVB59_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEL1009652.1"
                     /translation="MTEIPKDLKLNTISVFEHYHIDVFEAGHVLLSTEIHASALNYYG
                     NAHGGFLFTLCDQVGGLVAKSIGLEAVTLQANVNYLKPGHLGDRLVVEGSLVHRGRTT
                     QLIEVTIKNQDDRLLTRVSLTMFVTSKKRSSD"
     gene            complement(3376..4860)
                     /locus_tag="TVB59_000727"
     CDS             complement(3376..4860)
                     /locus_tag="TVB59_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEL1009653.1"
                     /translation="MKNIAFDSNKYLSLQRNHILERIKQFDGKLYMEFGGKILEDFHA
                     ARVLPGYEPDNKIKLLKELKDQVEIVITINANNIEHSKTRGDLGISYDQEVLRLIDTF
                     NALDIYVGSVVITQYNHQAAADHFQKQLAKNGITSYRHYPIKGYPTDINHIISPDGMG
                     RNDYIKTSRNLIVVTAPGPGSGKLATCISQLYHDQLKGVTSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLEAYGKTAVNYNRDIEVFPVLNRTFERILSQSPYA
                     SPTDMGVNMVGFSIVNEEAAIEASRQEIIRRYYQTLVDFKAERVTEAAVKKLELLMND
                     IGVTPKDRQVTLIARQKAEITGQPALALQLPNGQVVTGKTSDLFGPTAAVIINAIKTL
                     AHISKETHLIEPEYVKPIQGLKINHLGSHNPRLHANEILMALAITAMNNNQADLAMKE
                     LGNLKGSEAHSTVILTNEDKHVLRQLGINVTFDPVYQHHKLYRS"
     gene            5219..6442
                     /locus_tag="TVB59_000728"
     CDS             5219..6442
                     /locus_tag="TVB59_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1009654.1"
                     /translation="MSALSLDKNNKRALWAAIAASGTDDLNVMFLAFSMSSIISDLGV
                     SSTQGGWIATITNLGMLFGGLLFGLLADRHHKFKVFKWTILIFSVATGLIYFTKTIEF
                     LYLMRFIAGIGVGGEYGVAIAIMAGLVPAEKMGRVSSLNGIAGQVGSIVSALLAGWLA
                     PALGWRGLFLFGLAPILLVIWMMVAIDDDKIIDNHVNVSEEASQPVKISELFKTPALT
                     GQTLALMVMTTVQIAGYFGMMNWLPTIIQASLHISVKDSSLWMVSTIVGMCLGMLTFG
                     HLLDTFGPRLVYSIFLLLSSVCVYLFQFANSMSTMLIGGAIVGFFVNGMFAGYGAMIT
                     RLYPHHIRSTANNLILNVGRAVGGFSSVIIGKILDVSSVSMVMLFLALLYLVSFVALW
                     TIKNLKAERYQALTK"
     gene            complement(6532..6891)
                     /locus_tag="TVB59_000729"
     CDS             complement(6532..6891)
                     /locus_tag="TVB59_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase family protein"
                     /protein_id="HEL1009655.1"
                     /translation="MSIYSQLYETKSKHSAQAMGSGGLEVLATPALVAFMEHAAFTFL
                     QSQLKDKQTTVGSEIAIQHLAASKIGQAVTIVITALKEEGRKYDFRIEAFANHKLIGR
                     ACHTRVRVDQDAFLEKL"
     gene            7056..7769
                     /locus_tag="TVB59_000730"
     CDS             7056..7769
                     /locus_tag="TVB59_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEL1009656.1"
                     /translation="MRLDKFLVDAGLGSRSQVKLLLKKKQVSVNGVSQTSPKYQVNEM
                     TDEVSYQGQRLNYEAFVYYMLNKPKGVISATEDSSHKTVLDLLDDTARQKAVFPVGRL
                     DKDTHGLLLVTNDGKLAHALLSPKKHVAKQYLAVVDGMMTQEDVKHFAQGITLKDHQC
                     MPAHLDILEINESLKTSLVKITIEEGKFHQVKRMVAACGKTVSDLQRISMGPLQLDSA
                     LAPGAYRRLTAAELEALKA"
     gene            complement(7848..8675)
                     /locus_tag="TVB59_000731"
     CDS             complement(7848..8675)
                     /locus_tag="TVB59_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018164168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEL1009657.1"
                     /translation="MVLPHFDDYLEKYANLLIKKGVNIQKGHTLLISIAVEQHKLARL
                     LTKKAYEAGAAEVLVDYNDDQITREKLLKADEDRLLQVPDYVVEQSHYLLDQKASRLV
                     IRSANPNVFADIDSDRLAGATRATAIALEKQRAATQANKVSWNLAAAAGPEWAAMVFP
                     NLTSEEEQVDALWDAIFKMNRIYETDPVKAWDQHQERLEKKARLLNDYQFDSLHYRAP
                     GTDLRLGMPEQHIWEAAGLNRSTAHADFMIGSEQMDIDGITKDGEVIPIFRGGEWAI"
     gene            8936..9064
                     /locus_tag="TVB59_000732"
     CDS             8936..9064
                     /locus_tag="TVB59_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEL1009658.1"
                     /translation="MAFGENGPRKKTAFEKLTTVVVIVMVLVTVGGLIAGALSVLM"
     gene            9118..10431
                     /gene="obgE"
                     /locus_tag="TVB59_000733"
     CDS             9118..10431
                     /gene="obgE"
                     /locus_tag="TVB59_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEL1009659.1"
                     /translation="MSMFLDTAKVSVQAGRGGDGMVAFRREKYVPNGGPWGGDGGKGG
                     SVIFKVDEGLRTLIDFRYNRKFKAKSGEKGMTKGMHGRGSEDLIISVPQGTTVRDAET
                     GKVLTDLVEHGQEFVVAKGGRGGRGNIRFATPRNPAPEIAENGEPGEERQLELELKIL
                     ADVGLVGFPSVGKSTLLSVVSSAKPKIGAYHFTTIVPNLGMVRTKSGESFAMADLPGL
                     IKGASQGVGLGTQFLRHIERTRVILHVIDMSAAEGRDPYEDYVAINKELEAYNLRLME
                     RPQIIVANKMDMPEAKEQLQRFKEQLAAQYDDFEELPIIFPISSLAHQGLDSLLEATA
                     ELLAKTDDFLLYDEADLAEDEAYYGFAAEEKAFEISRADDAAWVLSGEKLERLFVMTN
                     LERDESIMKFARQLRGMGVDEALRERGAKDGDIVRIGKFEFEFVD"
     gene            10552..10710
                     /locus_tag="TVB59_000734"
     CDS             10552..10710
                     /locus_tag="TVB59_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009660.1"
                     /translation="MGDKPISFKDKDGNFVSAADVWNAEKLEELFNLLNPNRRLRLER
                     DKLKKDEA"
     gene            complement(10763..11467)
                     /locus_tag="TVB59_000735"
     CDS             complement(10763..11467)
                     /locus_tag="TVB59_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HEL1009661.1"
                     /translation="MAYLNYFTKTEWTLWLTSISAILLSAFFFGEQAPLALIASLIGV
                     TALIFSAKANPIGQSLAIIFSLIYAYLSLLNSYYGELITYLFMTLPMAILSLFTWLSH
                     PFEDQTSQVTISRLTTADRLRLVVLTILVTSLFYAILAYLKTAYLPVSTLSIATSFSA
                     AYLSYKRSPYFALAYALNDLVLILLWLYAAQANTSQYAVVICFAAFLVNDIYTFFNWL
                     HLQHHQEKKHQKRTKP"
     gene            11802..13202
                     /locus_tag="TVB59_000736"
     CDS             11802..13202
                     /locus_tag="TVB59_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEL1009662.1"
                     /translation="MKQSKRRYQFPEGFLWGSSTSGPQSEGTVSGDGKGPSNWDYWFS
                     LEPDKFHHQIGPEVTSTFYTNYKSDIALLKETGHTAFRTSIQWSRLIPEGVGQVNPKA
                     VAFYREVFQEIMAQDIKLIVNLYHFDLPYALQGKRGWEAKETVWAYETYAKTCFELFG
                     DLVDTWITFNEPIVPVECGYLGHYHYPCKVDAKAAVQVAYHTQLASSLAIKACHELYP
                     KHRISIVLNVTPAYPRSDQPEDVKAARIAELFQTKSFLDPSVLGVYPEELVVLLEAAD
                     LLPQYSADELAIIKNNPVDFLGVNYYQPLRVQAPSKTRQDGEPITLASYFEPYDMPGK
                     KVNPHRGWEIYEQGLYDIALNLKEHYGNIDWLVTENGMGVEGEEAFLVDGQIQDDYRI
                     AFIEDHLIQLHRALEEGANCKGYLLWTFIDCWSWLNAYKNRYGLVALDLETQKRTLKK
                     SGHWFKTLSQTNGFDK"
     gene            13212..14306
                     /locus_tag="TVB59_000737"
     CDS             13212..14306
                     /locus_tag="TVB59_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HEL1009663.1"
                     /translation="MVTLGFSLYPERHGFAKSKAYIDLLHCYGAKRLFMSLLQLAPND
                     PKTFKFYADLIAYANCLGIRVIADVSPAFIKQAGWSDQVIEEAHAFGLAGLRLDEALP
                     LEDIVRLTKNSFGLKIELNMSTDKSLLTALLKAAPDRSNLIGCHNFYPHAFTGLSLEH
                     FKEMSHFYHEHGIATAAFITAQSAKEGPWPLSEGLPTVEAHRQLPIDVQVELMKATGT
                     IDTVILSNQFITEDELVQCRQALDRSVMSIKVKPLVDLTDIEEKIICYPHCYRGDVSD
                     YVIRSTMPREVYAQEAIAPREQPKQVKRGSIIIDNDRYNRYKGELQIALKAFTLSSKA
                     NVVANIKEDYLSLLDELKPWQEFSLVIETD"
     gene            14412..16406
                     /locus_tag="TVB59_000738"
     CDS             14412..16406
                     /locus_tag="TVB59_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEL1009664.1"
                     /translation="MLSKKEMAIVAFLISQKGQFVSSATLAKAIGMSDRTVRKYLKEL
                     ISSLPSKGAHIISKQGQGYCLEIDHSMAFEIFWQESLASKKRLADVTQVEETVDREHY
                     LLNKFFFEEPVWDFEELCQELYISRTTLNHVLAVIRDRIRPYQLQLDVSHQRVQVTGK
                     EEAIRHFIMDYFFATSFDDSMYAIVDNTFLDHIKFADITIIVLDECRDAKLKLSDFVM
                     HNLVLHIALMVQRIRSGYPLAFFSIPAAIRQSDEYQVALRILYRVEEVMGIRFPKEEA
                     NYIALHLKVKHSVDGSPQDNKADDLLRSHLKAGIVKASQLTGMSLEADSSLLQGLLAH
                     MKPLATRLENHIQLTNPLTEEIKSKYPEAFALTKQAFENIPELQAYDLSDDEWAYISL
                     HIMAAIERYSNRHKLRVLVVCATGYGSAMMLKNRLEKEFEGRFQIVDVISYYEITQER
                     LQTVDVIISSISLANVMFLTPVITVSVFLSDQDIKAIRQFIGEQEGIRREAASSSQMS
                     LEKAEQILKGVFSPKRFLYVKEKLSKKALLLKMIACLDEAMDEAFVEAFYHQIVLREN
                     YSSIVFGEVLAFPHPANPMTYSEQVVVAVCQEPIDWDESHRAVHFIFLLSPSKGRNSY
                     LKYISPSLVSFVNQAELQQALLEEPSYAQFITLFTPLITE"
     gene            16420..16737
                     /locus_tag="TVB59_000739"
     CDS             16420..16737
                     /locus_tag="TVB59_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1009665.1"
                     /translation="MKTIMLVCNAGMSTSMLVTKMQKAAQARGIEVEIWAVPVSEADN
                     EVAAKTIDVLMLGPQVKFLLKDFKTKFEPAIKVDVINMADYGLMNGDKVLETALTMME
                     EEV"
     gene            16734..17069
                     /locus_tag="TVB59_000740"
     CDS             16734..17069
                     /locus_tag="TVB59_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEL1009666.1"
                     /translation="MTQSSNLEAIMGLIMYGGEAKGKAVEAIHAARDGQFEKAQHLLQ
                     EATHSLNVAHRSQTNLLSQEAAGDQVDLSLLLVHGQDHMMTALAFIDLAKELVAVYDK
                     ISRIQRGEL"
     gene            17069..17503
                     /locus_tag="TVB59_000741"
     CDS             17069..17503
                     /locus_tag="TVB59_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HEL1009667.1"
                     /translation="MMITAEGDVSVTQCFKAILSSLQEDYHENTLRRLPPAELKAGLS
                     YIKHYGKSKEHNVRVLITALEAPHLYAACFSSNHGLKTLSYRLEALGEKRTKITYCYD
                     YQPLDVFQKANQLIIGKLFKKSFKRQSQAQLAALIQYAKQLS"
     gene            17578..18957
                     /locus_tag="TVB59_000742"
     CDS             17578..18957
                     /locus_tag="TVB59_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL1009668.1"
                     /translation="MSHFSDKFMEISGKMGSQRHLVAIRDSFISLMPITMAGSVAVLL
                     NVFLRDIPNNMGWTGFAAAMQPIIDINGYVYFGTIGIMALFFAFAFGYHLALMHKVNP
                     LAGGLISFASFVATLPQSLTISTPLEGASASLLAGLKDMGLSVVTANGARVLETSQWG
                     AIALKYAGATGLFTALIIGFLSSFVYATLTKRNLTIKLPDNVPPAVNKAFAAIIPGTV
                     AIYVSAIVAYLIFALTGSSLSDMISTYIQLPLLGLSQGLGSVILLTFLVQLLWFFGLH
                     GHNVLAPVLDGVYLVALTENTAAYNTSQSVANLPYLWTRGSFDAYAQMGGSGVTLALI
                     IAIFIFSKREEHKTIAKLSAPMGVFNINEPITFGMPIVLNPTFAIPWLIVPPICASIA
                     YAATAIGLIPPVFLPVPWITPVGLYAYLATGGSVMAGLVSLFNLFVAFLIWAPFVMSA
                     NKEKASDLS"
     gene            18954..19106
                     /locus_tag="TVB59_000743"
     CDS             18954..19106
                     /locus_tag="TVB59_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009669.1"
                     /translation="MTAKNGASFLMAIGFFLIAISPMVGNKYLHIVTGLAFVGLGYYL
                     TKRKRP"
     gene            complement(19263..20003)
                     /locus_tag="TVB59_000744"
     CDS             complement(19263..20003)
                     /locus_tag="TVB59_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003107174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL1009670.1"
                     /translation="MAELKIDVQDLHKSYGQNEVLKGINAKFYEGDVVCIIGPSGSGK
                     STFLRTLNLLESITSGKVVVDGFELSDPNTNIDKARENIGMVFQHFNLFPHMTVLDNI
                     TFAPVELGKVSKEAAKEKGLALLEKVGLADKADAFPGSLSGGQKQRVAIARSLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKDLAEQGMTMLIVTHEMGFARQVANRVIFTDGGQF
                     LEDGTPEEIFDHPKHPRLIEFLDKVLNV"
     gene            complement(20003..22168)
                     /locus_tag="TVB59_000745"
     CDS             complement(20003..22168)
                     /locus_tag="TVB59_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEL1009671.1"
                     /translation="MKNTLKAWMLAMLSVVLMTAGIASAETIDIVSDTAYAPFEFKDS
                     DQVYKGIDVDIINEVAKRKGWNINMTFPGFDAAVNAIQSGQADALMAGTTITAARQKV
                     FHFSDPYYDTKIVIATRKANPIKKYSELKGKTVGVKNGTAAQAFLDKYKKSYGYTVKT
                     FDTGDLMYNSLATGSIDAVMDDEPVIQYAINQKQDLAINMKGEAIGSFGFAVKKGSGY
                     DYLIDDFNEALGAMKADGTYQAIMTKWLGSNDKVTAGKATGDASAKATPLKPVYKIVA
                     DSSFAPFEFQIGSGEYVGIDMDLIKAIAKQQGFTIEISNPGFDAALNAVQAGQADAVI
                     AGMSITPARREIFDFSDSYYTSNIRLGVKSGSSIKSYKDLKGKIVGAKKGTASYDFLE
                     SNKDIYGYRLKAFDEASSMYDSLNSGSIDGLMDDEAILRYAIQRGHKLDIPIKGEPSG
                     EYGFAVKKGANPELIEMFNNGLAALKASGKYDAIISRYLDSEASVKTADESTIYGLLA
                     NNYKQLLAGLGTTLGLTLISFAIALVIGIVFGMMAVSPSKNLRMASTIFVDVVRGIPL
                     MIVAAFIFWGVPNLIESMTGHQSPINDFVAATIALSLNGGAYIAEIVRGGIEAVPAGQ
                     MEASRSLGLSYHTTMRRIILPQAIKLMLPNFINQFVISLKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFRMYAILAVIYLIMITLLTRLAKRLEKRLN"
     gene            22360..24351
                     /gene="uvrB"
                     /locus_tag="TVB59_000746"
     CDS             22360..24351
                     /gene="uvrB"
                     /locus_tag="TVB59_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEL1009672.1"
                     /translation="MIDKRDFKAFKLVSKYAPSGDQPQAIETLVDNIEGGEKAQILLG
                     ATGTGKTYTMSQVISKVNKPTLVVAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEYA
                     DSAVSLRPGQEISRDQLLNALVDIQFERNDIDFQRGRFRVRGDVVEVFPASRDEHAFR
                     IEFFGDEIDRIREIESLTGKVLGDADHLVLFPATHFVTNDEHMEQSISKIQAELADQL
                     KLFEAEGKLLEAQRLRQRTEYDIEMLREMGYTNGVENYSRHMDGRSAGEPPYTLLDFF
                     PDDFLIMIDESHMTMGQIKGMYNGDKARKQMLVDYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYEMEQTDTIVEQIIRPTGLLDPEVEVRPSMGQMDDLLGEINLRVERG
                     ERTFITTLTKKMAEDLTDYLKEMGVKVKYMHSDIKTLERTEIIRDLRLGVFDVLIGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNADGHVIMYADRMTDSMQ
                     RAIDETARRRAIQMAYNEEHGIIPQTIKKDIRDLISISRAVEAKATEAETNYESMTRS
                     ERQEAIKQLQKNMQEAAELLDFELAAQLRDLILELKAMD"
     gene            24690..24833
                     /locus_tag="TVB59_000747"
     CDS             24690..24833
                     /locus_tag="TVB59_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEL1009673.1"
                     /translation="MLKNKSRLRAIFVFVGKIALFYVILMLLVYFFGYLGHGQSNFIY
                     NEF"
     gene            24845..26383
                     /gene="dltA"
                     /locus_tag="TVB59_000748"
     CDS             24845..26383
                     /gene="dltA"
                     /locus_tag="TVB59_000748"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEL1009674.1"
                     /translation="MVNDMIETIEYFAQAQPDFPVYDCLGERRSYGQLKEDSDSIAAL
                     IESLKLGEKSPVLVFGAQSYDMLASFVALTKTGHAYIPVDVHSAPERVLSIIEIAQPS
                     LIIAIEELPVSIDAIRVVSLAEIEAAKAAKAAFTMTSPVKGDDNYYIIFTSGTTGQPK
                     GVQISHANLLSFTNWMIEDAEFAIPERPQMLAQPPYSFDLSVMYWAPTLALGGTLFAL
                     PKEMVSDFKRLFSTIAELPIGIWTSTPSFADMAMLNDDFCQEKMPRLTHFYFDGEELT
                     VSTARKLFERFPDARIINAYGPTEATVALSAISITKDMIETYTRLPIGYPKPDSPTYI
                     IDEAGNALEPGQQGEIIVTGPAVSKGYLNNPEKTAEAFFTFNGMPAYHTGDLGSFTED
                     NVLLYGGRLDFQIKYAGYRIELEDVSQQLNQSPLVESAVAVPRYNKEHKVQNLLAYVV
                     LKDGVREQFARDLDITKAIKASVKDHMMAYMMPSKFIYREKLPLTPNGKIDIKFLINE
                     VNHQ"
     gene            26380..27627
                     /gene="dltB"
                     /locus_tag="TVB59_000749"
     CDS             26380..27627
                     /gene="dltB"
                     /locus_tag="TVB59_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEL1009675.1"
                     /translation="MTTLFHHIPYMEPYGNPIYFVYLIIAFLPVIIGIFKQRRFSTYE
                     SFVSLIFILLMFGGEHYQQLLAFLAYLIWQTISVLAYKHYRQKANAAWVFYLSILASL
                     FPLICVKVSLSLTRSFFSFLGISYLTFKSVGMIIEMRDGVLTDFSLKDFLRFMIFFPT
                     FSSGPIDRFRRFQEAYTKLPSRDVYLDMLNKAVMYLMLGFLYKHIISYCLGGLLLPLA
                     ENKALTVGGYFNKETIYVMYLYGLNLFFDFAGYSMFAIGLSYLLGIKTPENFNKPFLS
                     PNLKEFWNRWHMSLSFWFRDFVFMRLVHLLIKHKTFKNRNVTSGFAYLINMLVMGLWH
                     GLTWYYIAYGLFHGIGLIVNDAWLRKKKEINRRRKKQGLKPLFEGKVFHALSIVVTFH
                     VVLFSLLLFSGFLNELWFSRPLR"
     gene            27645..27884
                     /gene="dltC"
                     /locus_tag="TVB59_000750"
     CDS             27645..27884
                     /gene="dltC"
                     /locus_tag="TVB59_000750"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEL1009676.1"
                     /translation="MSTKETVIDLFDRLFMEDVSDMMDEDLFDAGVLDSLGTVELIVE
                     IESIFNIKVPISEFGREDWNTANKIIQGIEELQHA"
     gene            27877..29130
                     /gene="dltD"
                     /locus_tag="TVB59_000751"
     CDS             27877..29130
                     /gene="dltD"
                     /locus_tag="TVB59_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEL1009677.1"
                     /translation="MLKRLWLILGPLIIAFGLVCLTIFSFPTKLSYSLRQEKSNAVAI
                     NDSSFKNGLIKRQALSDPNYCFVPFFGSSEWSRMDSMHPSVLAERYKRSYRPFLIGKR
                     GSASLSQYYGMQQISQEITGKKAVFVVSPQWFTPQGIDPGAVQLYLSNSQVIDFLLKA
                     KASHKESQFAAKRMLDINPGVAKSELLRKISQGKALSRWDIRLLKWQQELSLREESLF
                     SFLGRSTNYEDRILPRVKGLPKTFSYERLSELAARRAKEGTSNNRFGIKNAFYSKRIA
                     PQFPLYKNFQCRNNYTVSPEYNDFQLVLSEFAKRKTEVLFVITPVNQAWANYTGLNQR
                     RYQKAVRKIKHQLTSQGFTRIADFSRNGGDKYFMEDTIHLGWNGWLAFDKEVVPFLED
                     QTPPSEYQLDPYFLSKDWADRTAGF"
     gene            29164..30138
                     /locus_tag="TVB59_000752"
     CDS             29164..30138
                     /locus_tag="TVB59_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEL1009678.1"
                     /translation="MLMSIIVILLILAIAVLVIEYGQKRSFSSWLLEKMFDYRKYKLS
                     KKADDYEGIETQRRRRIPYHLDNPEAVLGIPTTEYTIDGMQVFVINDQDSQDQPVIYY
                     LYGSVYLRRPETFHFKTIKHLIHLTNAKLVFPNFEKAPYVTYKEIYPKLAKTYQELCL
                     ANGAAKVSIIGDSSGGGMALALAQYLRDTQTAPQPKQLILLSPWLDVSFANQDYKHFE
                     AVEAYLDARRLRDIGELWAGSPEEMRSPYVSPLYGDYHDLPKIVTFVGTKEIFYPDIM
                     TLHERLMEQGHLNQLVIAEQMIHAYAIFPIREARQARKQIAELILKKE"
     gene            30679..31938
                     /locus_tag="TVB59_000753"
     CDS             30679..31938
                     /locus_tag="TVB59_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEL1009679.1"
                     /translation="MAWDWKKAGVVGVVSLASIMVLSACSGGHQKEAKQKDDNTIVVS
                     VDEGYADYIKEIKTAFEKDNKVKVKVKKEGMIDTLDKLSTDGPTGASPDVFLAPYDRV
                     GGLGSEGQIAEVSLGNADQFDDTVKKLVTINGKVYGAPDVIETLVMYYNKDLVSEAPK
                     TFTDIEELNKDPKFAFASEDGKSVGFLAKWTDFYYGYGLIAGYGAYVFGDKGTDPKDL
                     GIGNAGAIEGLDYAKKWYSVWPQGMQDTQKAGDFITEQFTSKKAGVIIDGPWAAASFK
                     EAGVNFGVAQIPSLPNGGSYQAFGGGKAWVISNYSKNKKLAQQFLDYVTNEKNQKAFY
                     DKTQEIPANLAARSYAAEQGNELTKAVIGQFSNAQPMPNIPEMAEVWGPGANMFFEVA
                     AGKKTPAKAAKEAAKTIQEAIAQKYTE"
     gene            32111..33811
                     /locus_tag="TVB59_000754"
     CDS             32111..33811
                     /locus_tag="TVB59_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HEL1009680.1"
                     /translation="MNTAGILHIPDSRYCFALSTKELVIRLRVAKEDNDIAVTLVYGP
                     KYHYHEYQKELAMYAAYTDHTHTYYEITLSLDDVRLAYIFKLEQSGHTYYFSEDGLTT
                     SYDFSNGFYNFFQMPYINAVDVHQTVPWVHNAVFYQIFVDRFHRGDFEKDDSYINMAW
                     LDRPTPNSFAGGDLKGITDKLEYLEDLGINVIYLTPIFKSISNHKYDISDYYAIDPMF
                     GTSLDLQQLINEAHQRGIRIILDAVFNHASSDCEPFQDVLAHGSASSFFDWFMIQGDH
                     PSVELANYETFADCHYMPKWNTSHQAVQDYLIEIGLYWITEYHIDGWRLDVSDEVSHD
                     FWRRFRKAVKAVKSDAILIGENWHDAYPYLQGDQYDGIMNYAFTKACLDYFAFDAISS
                     QEMAERLSHILMRNTWQVNQMNLNLLDSHDTHRFLTQVNGSKDKLLAGLALLVTFMGI
                     PCIYYGTELAMEGGYDPDSRRSFNWDSSTWDMSFWNQVKDIISLRRHAVIQFGSISIT
                     SHDDCLCVKRELNGQSIRLLVNNGVKPYPIEKGGSVLVSNGVDKETFELLQNGFVVSY
                     "
     gene            33840..35972
                     /locus_tag="TVB59_000755"
     CDS             33840..35972
                     /locus_tag="TVB59_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IPT/TIG domain-containing protein"
                     /protein_id="HEL1009681.1"
                     /translation="MKRITLTCRKALTVAMAAVTLAMSTNSVFAIENTAVSNKADFST
                     DTIYQIVTDRFHDGNAANNGNTDVFDKNDPKKYHGGDWAGIIKKLEDGYLTNLGVSAI
                     WISSPVENIDTIDPSNGSAAYHGYWAKDFFKANSHFGTMEDFKKLIQVAHGKNIKVVI
                     DFAPNHTSIAEYNGLTFPEDGALYKDGQLVGKFSHDDQKIFNHESWTDFSTYENSIYH
                     SMYGLADLNNLNPTVDDYLKEAIDKWLEMGIDGIRVDAVKHMSQGWQKNWLSHIYEKH
                     NVFAFGEWFADGSFNDPLMTKFADTSGMSLLDFRFANSVRRLYSDLSAKMQDFYNMIV
                     ATEKEYKEVSDQVTFIDNHDMTRFATLVNHNQTAVNQAYALLLTSRGVPNLYYGSEQY
                     ATGANDPENRGDMPTFDKNSTAYQVISKLAPLRKKNQALAYGTTQQRWINDQVLAFER
                     KFGNDVALVAVNKDQTNGYTISGAKTALPAGKYADELGGLLGGKELTVSADGNVEAFE
                     LGAGQVAVWTFKGQHETPQIGDVDASFGVAGNTVSISGQGFGSAQGQLHFGDSKADIV
                     SWDDTLIQFKIPAVAAGNHDIKVTTSTGQSSSPYKAFEVLTDKQIPVRLVVNNFNTVL
                     GEQLYIVGDVVELGANDNHKALGPIFNATQSIAQYPNWFYDVNLPINKTINCHLVKKD
                     SSGKVLWTSPETYTIKTDSKAQTISLKK"
     gene            36048..37352
                     /locus_tag="TVB59_000756"
     CDS             36048..37352
                     /locus_tag="TVB59_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1009682.1"
                     /translation="MLKNEKMKNPQKAMWLSIIPGLGQLYNTQKVKGFILLLVFLGEL
                     LEAFFVGIPALAGLYSLGSVPMEDHSLFLLIKGAMQLILFALFLIFHLAAMRDARLVA
                     REINAGHSISLTLKEMVQSIYEKGFPYLLIIPAYLAMAFAIVFPVLVTLLIAFTNYDF
                     RHIPPYKLLDWVGIKNFKSILELSTFKSAFGSVLSWTLIWTLAATSLQIVIGIATAII
                     ANQSFVKCRRIFGVIFLLPWGVPAFISIMSFGNFFNDSIGAMNVQVLPFLEKFVPFAD
                     FGIIPWKTDPFWTKVAVIMVQGWLGFPYIYILVSGILQSIPADLYEAATVDGATALQK
                     FRQITLPMIFAVAAPTLISQYTFNFNNFSIIYLFNNGGPGTVGGGAGSTDILISWIYK
                     LTTQTSPQFSIASAVTLIISLIVISVSLITFKKFKAFDMEDR"
     gene            37353..38213
                     /locus_tag="TVB59_000757"
     CDS             37353..38213
                     /locus_tag="TVB59_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1009683.1"
                     /translation="MGRNYLPQSVKKKRLLAQLLTYSYLLILSIIILFPILVTVSSAF
                     RPGNTTAFSFHIDGPWTLSNFETLFQDTYYLRWYWNTLVVAFFTMLIQVTVITLTGYA
                     YSRYHFFGRQKSLVFFLVVQMVPTMAALTAYFVMAWLFNALNHYWFLILIYVGGGIPM
                     NAWLMKGYFDTVPYDLDESAKLDGSGHFRTFYQIVFPLVRPMVAVQALWAFMGPFGDF
                     MLAKFLLREQEHYTVAVGLQSFITNDARDPKVTLFAAGAILIAVPISVLFFFLQKHFV
                     SGLTNGGTKG"
     gene            38238..39068
                     /locus_tag="TVB59_000758"
     CDS             38238..39068
                     /locus_tag="TVB59_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein malA"
                     /protein_id="HEL1009684.1"
                     /translation="MTNDRFPISYTTIIFSPKMIFARCSAFLWWQNVILVIFLNALVL
                     MPITLHYASLKSYPLEHIVSNGLDSLTEKTYHALTQGTIWHDRYDGKTVLIEDTDAVV
                     AVLPTPEIVEELKKDQRSQLILTETSWILSFPDGQRLTAKVKGNKERLTRLTSLEAVK
                     AFVNQQWYNSNRAAVLAFLLLVASSVVYLGAGLVIGIGSLSLLLTRSARLFSLKSYSE
                     CLGLLVNCFGLPTLLAVLISFWVHNPIVIMNSQVFGTLLMLVLVFYKTQFRDEEQALA
                     "
BASE COUNT        10877 a         7379 c         9049 g        11789 t
ORIGIN      
        1 tgatagtgga aattatcact caagaagtac ggggtatcag agcaagactt attttaatct
       61 gagtaagctt cttgtcctta ggctcaagct gatcaggact gagtgaccac ccatttaaac
      121 cggggaacaa ggtagctaac gataatgctg ctaagtccaa taatggttag ccaataaagc
      181 cagctggaat caaagctaag cacgagatga cttccaagga caagcacaac accagaccaa
      241 aacaagatta gattaatcgg gttatcagtg atagtgacct gatcttgatt ggtcacgatt
      301 ttcttggcct gcctgctatg cttgatggtc aaataatcct cagcatcggg gagatcaata
      361 tcgatactct cacccggata aagcttaacc ttgtgggatt tcccgatatt aactgtcata
      421 ggtgctccta tctttgtcaa acgtgtcttg cgccttagct tcattcctaa aatcctctct
      481 aaaataaaag tcaagcataa tcatgccaat tccagccttc aaatgctaca aaagaccagt
      541 gtaccatagc ctatgatacc aaaaagcaga aagaatagcg actgtaaaaa atctgaaaat
      601 aagctttctt acatctattc cctgctttga aagcagactt ttgcaggatc tatgctagaa
      661 tagaaggaaa aggagggcac taatggttaa gggaataata tttgacatgg acggcgtttt
      721 atttgatacg gagccttttt atctcaaacg tcgtgaagcc tttttgacga gtaagggcat
      781 taggattgac cacctcagcc ccgaggattt tattggtggt aatcttcagc agatttggga
      841 caaggtctta gcagggcagg ctaatgctga tgaggcaaga gatattgctg tggcttatga
      901 ggcctataag ctgtgccata agcctcctta ccaagagctg atgtttaaag gggtcaagtc
      961 ctgcctcaaa gctcttaaag ggcagggact taagcttgct ttagcctcaa actctagtcg
     1021 ttgtgatatt ttgttagctt tagagagcag tcatatcaag gcttattttg accttacact
     1081 ggcgcgtgag gacgtcacag ctggtaagcc taatcctgag atttataaca aggttgcgca
     1141 ggctctggga ctggctaaag cagagtttgt cgttgtcgaa gatagtcaaa aagggattgc
     1201 cgcagctaag gctgctggct tgaaggttct agcaatcaaa gacaagcgtt acggcattga
     1261 tcaaggtcag gcagacaagc gcattgatag cctcaggcag ctatgtgagc tgcttaggta
     1321 aggcttctga tagagcagat gtttgttaac tgaaagatag caggctttat agtggcttat
     1381 catcactaca atagaatgat ttgtcttaga atgacagaac ctaaataggt gtttttctcg
     1441 tttttgtagc aggatagctg aagcttttga tctgctttat gtttggtgtt gttattaaga
     1501 gatgaaattg tcagtaatgt tgagcttact gataggaggg ctaatggcag ttaaattatt
     1561 aacagaaaga ttgatcatac aggagttgaa tgagacctat tttgagcctt atcacaaggc
     1621 atttaccgaa gaaatcacag catttcaatg gcctgatccc tttaaggaca tcgctgctgc
     1681 taaggagaca ctagctagct ttatcgcaga aatgaaaaaa ggaaacatgc tagagctagt
     1741 cattttgaat aaagcaaatg acttcgttgg aagcttggaa gtctttagcc ttgatagtga
     1801 gacaccggaa ttgggcatat ggttgaaaaa atcaagtcaa ggactaggct atggctatga
     1861 ggccttgaga gctattgtgg attatttaaa aggcaaaaac aaataccgtt atttcaatta
     1921 tgaggtagat gttagaaata ctggtaatat taagctggta gagaaattca atgtggtgac
     1981 atcgacctat caggaatgtg agacggcttc aaagaaaagg ctttgtttac aggtttatca
     2041 cattcttaat taatcgttgg tatgacatag gtgatagtca tggttttgct ttaagtcctg
     2101 tgtgagttga gagcagcttt cagctctagt atttgcttct ggtgtggtct tttagtccac
     2161 agtctaggta ttataaagaa gagatctggc tttgtttaaa aaacagcttc tctgtctgag
     2221 cttgtaccct caagatatca ttgaagagat agcaggacag ctgttgaaaa tgagggaagt
     2281 aagagggatc tgtgtgccaa gatcaaaagc ataaaaagcc tctagcttac ttcttgtggt
     2341 tagcattttt ttgaaagcat gctaatttgc ctttagtgtg ctttttgttt gctcaagatc
     2401 agctagtcaa tgaggccata gagtaagcct taacaaatgg tgagatgtag ctacagccgg
     2461 ttgtgcagat ggggttagaa taattggatc tactcacagc ctcttgtaat catttcctta
     2521 caaaaatcac actagtaaag acctctaatg gcgaaggagc tcctgacacc aagctctgaa
     2581 gaagctggct atttgtcctt gatcaaaaag ggttaagact gtcagttcaa ctaggtgcaa
     2641 acgactcata aggcaggtct ttagcagggg tgatgtcaaa aaattgacat cagctgtaac
     2701 cttttagcaa aattgtagtc caacaaaagt gagcagacat tttggaaggg ggacctgtta
     2761 ttggaatttg aagacatcta cttgatgtat aaagacgatg tttatccttt tcttcatgcc
     2821 tatgcgtgag acaacttatg acgaggttga accaagggct ttctttatag tataatggtc
     2881 gttaaagtga tattaataag aaagtgatga ctataatgac agaaatacca aaggatttaa
     2941 agctaaatac gattagtgtc tttgagcatt atcatattga tgtgtttgag gctggtcatg
     3001 tgctgttatc aacagagatc catgcgtcag ccttgaacta ttatggaaat gcacatgggg
     3061 gctttttgtt taccctttgt gatcaggttg gtggcttggt ggccaaatca ataggtcttg
     3121 aggctgttac tctgcaagct aatgtgaatt atcttaagcc tggtcatcta ggagaccgtt
     3181 tagtcgtaga aggtagtctg gtgcatagag gtcggaccac acagctgatt gaggtcacca
     3241 tcaaaaatca agatgataga ctattaacca gggttagcct gaccatgttt gtgacaagta
     3301 aaaaacgatc ctctgactag ctgatacaag tcatatcaaa aaacgtccag cttgatttta
     3361 gctggacgtt tggctttagc tgcgatagag cttatggtgc tgataaacag ggtcaaaggt
     3421 cacattgata ccgagctgtc tgagaacatg cttgtcctcg ttggtcagga taacggttga
     3481 atgcgcttcg ctgcccttga gatttcctaa ttctttcatg gctagatcgg cttggttgtt
     3541 gttcattgct gtgatagcca gcgccattag gatttcatta gcgtgtagcc tagggttgtg
     3601 actgcctagg tgattaatct tgagcccttg aatgggcttg acatattctg gctcaatgag
     3661 atgcgtttcc ttactaatgt gggccagtgt tttgatagca ttgatgataa cagcagcggt
     3721 cggaccaaac aaatcagatg ttttaccggt gactacctga ccatttggaa gctgaagggc
     3781 tagggcaggc tgaccagtta tctctgcttt ttgcctagca atgagagtaa cctgtcgatc
     3841 tttgggagtg acaccgatgt cattcatcaa gagctcaagc tttttaactg cagcctcggt
     3901 cacgcgctcc gctttgaagt ctaccaaggt ttgatagtag cggcgaatga tttcttgcct
     3961 tgaggcttcg atagcagcct cctcattaac aatggaaaag ccgaccatat taacacccat
     4021 atctgttgga gatgcatatg gggactggct taaaatacgc tcaaaggttc tgtttagtac
     4081 tggaaagacc tcaatatcac gattgtaatt gactgctgtt ttcccgtaag cctctaaatg
     4141 aaagggatca atcatgttca catcatctaa atcagcagtg gcagcctcat aggctaggtt
     4201 tacagggtgg tggagtggaa gattccaaac agggaaggtt tcaaactttg catagcctga
     4261 tgtgacaccc tttagttggt catgatagag ctgtgagatg caggtcgcta attttccaga
     4321 gccaggacca ggagctgtga cgacaatcag gttacgactg gtcttgatgt agtcatttct
     4381 ccccatacca tcaggagaaa tgatgtggtt aatatctgtt ggatagcctt tgattgggta
     4441 gtggcgataa gacgtaatgc catttttggc taattgcttt tgaaaatgat ccgcagctgc
     4501 ctgatggttg tactgcgtaa ttacaactga gccaacatag atatctaagg cgttaaaggt
     4561 atcaattaaa cggagcactt cctgatcgta ggagattcct aagtcaccac gcgttttaga
     4621 atgttcgata ttattggcat tgatggtgat gacaatctca acctgatcct tgagctcctt
     4681 tagcagcttg attttgttgt caggctcata gccaggcaag acacgcgccg catgaaaatc
     4741 ctcaagtatt tttccgccaa attccatgta gagcttgccg tcaaattgct tgatacgttc
     4801 tagaatatga ttcctttgta agcttaggta tttgttggaa tcaaaagcaa tgtttttcat
     4861 ttatttttca cctctgctaa gcattatagc aaagaaatag tgagaagtga atgatttgtc
     4921 taaaaattag tctcttcctc taagtagcta gggtggcaaa aagcagcgct atttaaatac
     4981 cgataaaaaa tgacttgaca aaggtgactg acttgcttat actaggaaca attaaatacc
     5041 actttaatga tgttctgtga ggcatgaaag tgacaagaca aagaggagtg agcctgctct
     5101 tattttgctg tagactgaat gcgactgatg gactggtgcc taggtctttt ttaatgggct
     5161 taaagggtat tcaattaatt aaggtagtca gtgagctact attaaaagga gaataatcat
     5221 gtcagcattg tctttagaca agaacaacaa gcgtgcgctt tgggctgcta ttgccgcttc
     5281 aggaacagat gatcttaacg ttatgtttct agccttttcg atgtcctcta ttatctctga
     5341 tctaggagtg agtagtactc aaggaggctg gatagctact atcactaatc taggaatgct
     5401 ctttgggggc ctgctctttg gtctgcttgc tgatagacat cataaattta aggtattcaa
     5461 atggacgatc cttatttttt cagtggcaac aggcttgatt tattttacca agacgattga
     5521 atttttatac ctcatgcgct ttattgctgg tattggggtt ggtggtgaat atggtgttgc
     5581 tattgcgatt atggcaggac ttgtccctgc tgaaaaaatg gggcgcgtct catcgctaaa
     5641 tgggattgca ggtcaggttg gatcaattgt ttctgcttta ttagcaggct ggctagcacc
     5701 tgctcttggc tggcgcggcc tctttctctt tggtctggct ccgattttac tagtcatttg
     5761 gatgatggtt gctattgatg atgataagat tattgataac catgtcaatg tttcagagga
     5821 agctagtcag ccggtaaaga ttagtgagtt atttaagaca ccagccttga caggacaaac
     5881 tctcgctttg atggtgatga cgacagttca gattgctggt tattttggta tgatgaactg
     5941 gctgccaact attatccaag ctagtctaca tatttctgtc aaggattcgt ctctgtggat
     6001 ggtatcaacc attgtgggca tgtgccttgg aatgctgacc tttggccatc tgctagatac
     6061 ctttgggcca agattggttt attctatctt tttgcttttg tcctctgttt gtgtctatct
     6121 ttttcagttt gccaattcga tgtcaaccat gcttattgga ggagctattg ttggattttt
     6181 cgttaatggc atgtttgcgg gctatggtgc gatgatcaca cgactctatc ctcatcacat
     6241 tcgatcaaca gctaataacc ttatcctcaa tgttggacga gctgttggag gcttttcatc
     6301 ggttatcatc ggtaaaattc ttgatgtttc aagtgtctct atggtcatgc tctttttagc
     6361 cctgctgtac cttgttagct ttgtggcttt gtggacaatc aaaaatctaa aggcagagcg
     6421 atatcaagcg ctgacaaaat agatctggta agtgtagtag gattagtagc aaaggttttg
     6481 ttaaagctct caaaaagcgc ttaggcattt agactaagcg ctttttgacc tttaaagctt
     6541 ttccaaaaag gcgtcttggt caaccctgac acgtgtgtgg caggctctgc caatgagctt
     6601 atggttggca aaggcttcga tacgaaagtc gtattttctg ccctcttcct tgagtgcagt
     6661 gataacaatg gttactgcct gaccgatttt agaggcagct aggtgctgga tagcgatttc
     6721 acttccaacg gttgtttgct tgtcctttag ctgactttgc agaaacgtga aggcagcatg
     6781 ctccataaag gcgacaagag caggtgttgc taggacctct aagccaccag agcccattgc
     6841 ttgagcagaa tgcttgcttt ttgtttcgta tagctgtgaa taaatagaca tgataccctc
     6901 cttttttatt attataatat attaagggct tacagtctta aatgagctgc cttttgtgct
     6961 atactaagaa ttagcttgaa agagctgttg ctgaattaat gtgtctcgca tgggccagac
     7021 taagcatcag ctaacagtaa gaagaagggg aatacatgcg cttagataag tttttagttg
     7081 atgctggctt aggcagtcgc agtcaagtga agctgctatt aaagaaaaag caagtcagtg
     7141 tgaatggggt tagccaaacg tctccaaaat atcaagtcaa tgaaatgacc gatgaggtta
     7201 gctatcaggg acaaaggctc aattatgagg cctttgtgta ttatatgctt aataagccta
     7261 aaggagtgat ttctgcgact gaggattcta gccataagac agtgctggat ttgttagatg
     7321 atactgcacg tcaaaaggct gtctttcctg ttgggcggct tgataaggat acgcatggct
     7381 tgctcttagt gaccaatgat ggaaagctag cacatgctct tttgtctcct aaaaagcatg
     7441 ttgccaagca ataccttgct gtggtagacg gtatgatgac tcaagaggac gtcaagcatt
     7501 tcgcacaggg aatcacttta aaggatcacc aatgcatgcc agcacatttg gacattcttg
     7561 agattaacga atcgctaaaa accagccttg tcaaaatcac catcgaggaa ggaaaatttc
     7621 atcaggttaa gcgaatggta gcagcctgtg gtaaaacagt cagcgattta cagcgcatta
     7681 gtatggggcc cttacagctt gatagtgctt tggcgcctgg agcctatcgt aggttaacag
     7741 cagcagagct agaggcctta aaagcctaag gctagactag tcactggctg ggttagctgc
     7801 tgaattgata gtaaaaaaga ccagtcttag actgatctgt agggtgatta gatcgcccat
     7861 tctcctcctc ggaagattgg aatgacttct ccgtctttgg taatgccatc gatatccatt
     7921 tgttcagaac caatcataaa gtccgcgtgg gctgttgagc gatttaggcc agccgcttcc
     7981 caaatgtgct gctcaggcat tccaagtctt aggtcagttc ctggtgccct gtagtgaagg
     8041 ctgtcaaact gataatcatt gaggagcctt gccttttttt ctaaacgttc ctgatgttgg
     8101 tcccaggcct tgacaggatc tgtctcgtaa atgcgattca ttttgaaaat ggcatcccac
     8161 aaagcgtcca cctgctcttc ttcgcttgtc aggtttggaa aaaccatagc agcccattcg
     8221 ggaccggctg cagctgctag attccagctg actttgttgg cctgagtggc agcccgctgt
     8281 ttttcaagag caatagctgt tgcgcgtgtt gctccagcta gcctatcaga atcaatatca
     8341 gcaaagacgt ttggattggc agagcgaatg actaagcggc ttgctttttg atcaaggaga
     8401 taatgtgact gttcaacgac ataatctggt acctgcaaga gacggtcttc atcagcctta
     8461 agaagcttct cgcgtgtgat ctgatcgtca ttatagtcaa caagaacctc agctgcacca
     8521 gcctcatagg cttttttggt taatagccgc gcaagcttgt gttgctctac tgcaatagaa
     8581 atgagtagtg tgtgaccttt ttgaatgttg actccttttt tgataagaag gttagcgtat
     8641 ttttcaagat aatcgtcaaa atgtggcaaa accatagcag tctcctaata tgttaatgtt
     8701 gcaaaattta atgtatcata tttgcgacta tttcacaagg agctagcctg tttcataggc
     8761 taaatgtctc ctagaatgcc tatcgtaaaa ggctcagtgt tggttttctc tgatgagtta
     8821 aaaaacgatc ccttttttga tcagtttgcg ctgcccttgc taatagatat ttgcttaata
     8881 gcgacattcg tgttaagata taagaggaaa aaatcaatag atgaggtatt taacagtggc
     8941 atttggagaa aatggacctc gcaaaaaaac tgcctttgaa aagttgacaa cagttgttgt
     9001 gatcgtgatg gttcttgtga ctgtcggtgg acttattgcg ggtgccctgt cagtattgat
     9061 gtaagaaaac gctgaaaggc gtttttttag gataagagaa ggtttgagaa gaaaagtatg
     9121 agtatgtttt tagatactgc taaggtcagt gttcaggctg gtcgtggcgg tgatggtatg
     9181 gtggcctttc gtcgtgaaaa atatgtgcct aatggcggcc cttggggcgg tgatggtggc
     9241 aagggtggct ctgtcatttt caaggttgat gaaggtttgc gtaccctaat agactttcgc
     9301 tacaatcgta agttcaaggc caaatccggt gaaaaaggca tgactaaggg catgcatggt
     9361 cgtggctcag aggatttgat tatctcagtg ccacagggaa cgactgtgcg tgatgctgaa
     9421 accggtaagg ttctgacgga tctggttgag catggtcaag aatttgtcgt ggctaagggt
     9481 ggtcgtggcg gtcgtgggaa cattcgtttt gcaacgccgc gcaatccagc acctgagatt
     9541 gctgaaaatg gtgaaccagg agaggagcgc caattagagc tagagcttaa gattttggca
     9601 gatgtgggac tggttggttt tccgtcagtt ggtaaatcaa cgctactaag cgtggtctca
     9661 tcagccaagc ccaagattgg tgcttatcac tttaccacta ttgtgcctaa tctaggtatg
     9721 gttcgaacca aatctggtga gagctttgct atggcagatc ttccaggctt aatcaaggga
     9781 gctagccagg gtgtggggct tggcactcag tttttgcgcc atattgagcg tacacgtgtg
     9841 attctacatg ttattgatat gtcagcagct gaaggacgag acccttatga ggactatgtg
     9901 gcgattaata aggagttaga agcatataat cttcgtctta tggagcgtcc gcaaattatc
     9961 gtcgccaata aaatggatat gccagaggca aaggagcagt tgcagcgctt caaggaacag
    10021 ttagctgctc agtatgatga ctttgaagaa ctgccaataa ttttcccgat ttctagcttg
    10081 gcacatcaag gcttggatag cctattagaa gcaacagcag agctattagc aaaaactgat
    10141 gatttcttgt tgtatgatga ggctgatttg gctgaggacg aggcttatta tggctttgcg
    10201 gctgaggaaa aggcctttga gattagtcgt gctgatgatg cagcttgggt attgtctggt
    10261 gagaaattag agcgtctctt tgtgatgacc aatctggagc gcgacgaatc tatcatgaaa
    10321 tttgctcgtc agctacgtgg catgggtgtt gatgaagcgc ttcgtgagcg tggtgctaag
    10381 gacggcgaca ttgttcgcat tggcaagttt gagtttgaat ttgtagacta atgacaaata
    10441 ccaagcttag ctgttttttg tagcaagtga tgctgagtca tatctgaagt aggctgtttg
    10501 ctcaattcac agcaatgagg tcttggttga tgtgagctag ggaggttttt tatgggagat
    10561 aaaccaatat ccttcaagga taaggacggt aactttgttt cggcagcaga tgtctggaat
    10621 gctgaaaaat tagaagaatt atttaatctc ttaaatccca ataggcgttt gcgtttggaa
    10681 cgtgacaaat taaaaaagga tgaagcttaa gtgcacttcc tctcaatcgt tagatttagt
    10741 gtctaacttt tgagggtgca cttcaaggct tcgtcctttt ttgatgcttt ttttcttggt
    10801 gatgctgcaa atgtagccaa ttaaaaaagg tgtaaatgtc attaacaaga aaggctgcaa
    10861 aacaaatgac cactgcgtat tggctggtat ttgcttgagc agcatagagc cacaggagaa
    10921 ttaagaccaa atcattaaga gcataggcca aggcaaaata agggctacgt ttgtagctta
    10981 agtaggctgc tgaaaaagag gtggcaatag ataaggtaga aacaggcaga taggctgtct
    11041 taagataggc taagatagca tagaacaagc tggtaactag tatggtaaga accactaagc
    11101 gcagccggtc tgctgttgtc aagcgtgaga tggttacctg agatgtctgg tcttcaaatg
    11161 ggtggcttag ccaggtaaac agtgacaaaa tagccatcgg cagggtcatg aagagatagg
    11221 ttatcagctc cccgtaataa ctgtttaata gtgacagata ggcataaata agggagaaaa
    11281 taatggccaa gctctgtcca atcggatttg ccttggcact aaagattaaa gctgtcacac
    11341 cgattaagga agctatcagt gctaagggag cttgttctcc aaagaaaaag gcactgagga
    11401 gaatagccga aatggaggtt aaccaaagcg tccactcggt ttttgtaaaa tagtttaaat
    11461 aagccatatc cttattcaag cataggcctt tttatctgtc aatagggtgt cgaccttagg
    11521 gaaaaataag ctaatacctg ccatagtgca attggttgtg aggcactaat actagcagat
    11581 aatggtgtta actagaggca aatgagctaa gagtttcctt attggctgct gctaatactc
    11641 cttgttgact ggtttagaag aaaaggacta agagccttag cttggctttg tcagttagtt
    11701 tccttgatga taaggaaaaa ctagattttt taaagcgttt acagtgtcct tttttcttcc
    11761 tataataggg gtataagtga caaaaagaaa ggaaaaagca tatgaagcaa tcaaaacgcc
    11821 gttaccaatt tccagaaggt tttttgtggg gaagctcaac atctggccct caaagtgagg
    11881 ggactgtttc tggagatggg aagggaccta gcaattggga ctactggttt agtctggagc
    11941 cagataagtt tcatcatcag attggtccag aggtaacctc aaccttttac accaactaca
    12001 aaagcgatat tgctctttta aaagagaccg gtcacacagc ttttcggacc tctattcaat
    12061 ggtctcgact gattccagaa ggggttggtc aggttaatcc aaaagctgta gccttttacc
    12121 gagaggtatt tcaggaaatc atggctcagg acattaagct gattgttaac ctctatcatt
    12181 ttgatctgcc ttatgccttg caaggaaaga gaggctggga ggctaaggag acggtctggg
    12241 cttatgagac ctatgctaag acctgttttg agctttttgg tgatttggtg gatacatgga
    12301 ttacctttaa cgaacctatt gttccagtcg aatgcggtta tttggggcat taccactatc
    12361 cttgcaaggt agatgccaag gcagctgttc aagtggctta ccatacccag ttggctagct
    12421 cacttgctat caaggcctgc cacgagttgt atcctaagca taggattagt attgtgctta
    12481 atgtgactcc tgcctatcct agaagtgatc agccagaaga tgtcaaggca gcgagaatcg
    12541 cagagctttt ccagactaaa tccttcctag atccgtctgt cttaggagtg tacccagaag
    12601 agttagtagt tcttttagag gcagctgatt tattgcccca gtatagtgct gatgaattgg
    12661 ctattatcaa aaacaatcct gttgatttct tgggagttaa ttactatcaa cctttgcgtg
    12721 tgcaagcgcc tagcaaaaca agacaagatg gtgaaccaat cacgctagcc tcttattttg
    12781 aaccttatga tatgccaggc aaaaaggtta accctcatcg cggttgggaa atctatgagc
    12841 agggccttta cgacattgct cttaatttaa aagagcatta tggcaatatt gactggttag
    12901 taactgaaaa tggtatggga gtagaaggtg aagaagcctt tttagttgat ggtcagatcc
    12961 aagacgatta ccggattgcc tttatcgaag accatttgat tcaattgcac agggctttag
    13021 aagaaggcgc gaactgtaaa ggctacctcc tgtggacctt tattgattgc tggtcttggt
    13081 taaatgccta taaaaatcgt tatggcttgg tagccttgga tttagagact caaaaacgaa
    13141 cccttaaaaa atctggccac tggtttaaga ccctgagtca gacaaatggt tttgataaat
    13201 aggagcgtat gatggtcacc ttaggatttt ccctttaccc tgagcggcat ggttttgcta
    13261 agagtaaggc ttatattgat ttactgcact gctatggagc caagcgcttg tttatgagcc
    13321 tcttacagtt ggcgccaaat gatcccaaga cctttaagtt ttatgcggat ctgattgctt
    13381 atgccaattg cttgggcatt cgggtcattg cagacgttag ccctgctttt atcaagcagg
    13441 ctggttggtc agatcaggtt attgaagagg ctcatgcttt tggcttagca ggcttgcgtt
    13501 tagatgaggc cttgccttta gaggatattg ttaggctaac gaaaaactct tttgggctta
    13561 agattgaact caatatgagt actgacaaga gtttattgac agccttgcta aaggcagctc
    13621 ctgatcggag taacctcatt ggttgtcata atttttaccc gcacgccttt accggcctgt
    13681 cactggagca ttttaaggaa atgtcccatt tttaccacga gcatgggatt gcaacggctg
    13741 cttttatcac agcccaatca gcaaaggaag gcccttggcc gctgtcagag ggcttaccga
    13801 ctgttgaggc tcatcggcaa ttgccaattg acgtgcaggt ggaactgatg aaggcgacag
    13861 gaactattga tactgtcatt ttgtccaatc aattcatcac tgaagatgaa ctcgttcagt
    13921 gccgtcaagc cttggataga tcagtcatgt ctattaaggt caagcctctg gttgatttga
    13981 cggacataga ggagaagatt atctgttacc cacattgtta tcggggagat gtatcagatt
    14041 atgtgattcg ctcaaccatg ccgcgtgagg tatatgctca agaagcaatt gctccaagag
    14101 agcagcccaa gcaggttaag cgaggcagta ttatcattga taatgaccgt tacaacaggt
    14161 acaagggaga attgcaaatt gcactcaaag cctttaccct tagctcaaag gccaatgtgg
    14221 tcgccaacat taaagaggat tacctaagcc tattagacga gttgaagccc tggcaggagt
    14281 tttcattggt gattgagact gactagtctg gcttcacaat cgatacggaa aatgatggtc
    14341 acttttttca ggaaacattt gctaaactaa gagagtaaag aaagcgtttt ctaaaagacg
    14401 aaggaggaat gatgctatca aaaaaagaaa tggctatagt agcatttcta atcagccaaa
    14461 aagggcagtt tgtctctagt gctaccttgg ctaaggctat tggcatgagt gatcgcacag
    14521 tcagaaaata cctaaaggag ctgattagca gccttcctag taagggagcg cacatcattt
    14581 ccaagcaagg tcagggctac tgtttagaga ttgatcattc tatggcgttt gagatctttt
    14641 ggcaggaaag cttggcctct aaaaagcgct tggctgatgt gactcaggtg gaagaaacag
    14701 ttgatcggga gcattatttg ctaaataaat tcttctttga agagcccgtt tgggattttg
    14761 aagagctctg ccaagaattg tatattagtc ggacgaccct aaaccatgtt ttagcggtta
    14821 ttagagaccg tattaggcct tatcagctac agcttgatgt gagtcatcag cgcgttcagg
    14881 tgacaggtaa ggaagaggct attaggcatt ttatcatgga ttattttttt gctaccagct
    14941 ttgatgactc catgtacgcc atagtagaca atacctttct tgatcatatc aagtttgctg
    15001 atatcacaat aattgtttta gatgaatgtc gagatgccaa actaaagctt tctgattttg
    15061 tcatgcacaa tttggttttg cacattgccc taatggttca gcgtattcgg tctggctatc
    15121 cgttagcatt tttttccatt ccagcagcta ttcgccaatc agacgagtat caagtggctc
    15181 tacgtatttt atatcgagta gaagaagtga tgggcattcg ttttcctaaa gaagaagcta
    15241 actatattgc tttacacctc aaggttaagc attccgttga tggcagccca caggacaata
    15301 aggccgatga cttgctgaga agtcatttaa aagcaggtat tgtcaaggct agtcagctga
    15361 caggtatgtc tttggaggct gatagcagct tgcttcaagg cctattggcc catatgaagc
    15421 ctttagccac aaggcttgaa aatcatattc agctgaccaa tcccttaact gaggagatta
    15481 aaagcaaata cccagaggct tttgccctga ctaagcaagc ttttgagaat attcctgagc
    15541 ttcaggctta tgacctgtct gatgacgaat gggcttacat tagcttgcat atcatggcag
    15601 ctattgagcg ctattccaat cgtcacaaac tgagggtgct tgtggtttgt gccacaggct
    15661 atggcagtgc catgatgctg aaaaatcgct tggaaaagga atttgaaggt cgctttcaga
    15721 ttgtagatgt tatcagctac tatgaaataa cacaggaacg actgcaaacg gttgatgtga
    15781 ttatttcttc tatcagcctt gctaatgtca tgtttttaac gccagtcatt actgtcagtg
    15841 tctttttatc tgatcaagac atcaaagcca ttcgccaatt tatcggggag caggagggaa
    15901 taagaagaga agctgcgtcg tcatcgcaga tgagcttgga aaaagcagag cagattctaa
    15961 aaggtgtctt tagtcctaag cgttttcttt atgtgaaaga aaaactatca aagaaggcct
    16021 tgctgttaaa gatgattgct tgtcttgacg aagcaatgga tgaagccttt gttgaggcct
    16081 tttatcacca aatcgtgttg agggaaaatt atagctcaat tgtttttggt gaggtgcttg
    16141 cctttccaca cccggctaat cccatgacct attctgaaca ggtggtggtg gctgtctgtc
    16201 aagagcctat tgactgggac gagagtcatc gggctgttca ctttatcttt ttgttgtcac
    16261 cgtccaaggg acgtaacagc tatttaaaat atatctcacc gagcttggtg tcttttgtca
    16321 atcaagcaga gcttcagcag gctttattag aagaaccaag ctatgcacaa ttcatcacat
    16381 tatttacccc actcatcact gaataaaagg agaagtatta tgaaaaccat tatgttagtt
    16441 tgtaatgccg gcatgtcaac cagtatgctg gtgactaaaa tgcaaaaagc cgctcaagcg
    16501 cgtggcatcg aggttgagat ttgggcagtt cctgtgagcg aagctgacaa tgaggttgct
    16561 gctaaaacca ttgatgtcct catgttaggg ccgcaggtca aattcttact aaaggacttt
    16621 aagaccaaat ttgaaccggc aattaaggta gatgtcatta acatggctga ctatggcctc
    16681 atgaatggtg acaaggtgct tgaaacagcc ctaacaatga tggaggaaga ggtatgacac
    16741 aatcatcaaa cctagaggcc attatgggat taatcatgta tggcggtgag gccaagggca
    16801 aggctgtaga agctattcat gcagctagag atggtcaatt tgaaaaggct cagcacttgc
    16861 ttcaagaggc tacacattct ttaaatgttg cccatagatc acaaaccaat ttgctatctc
    16921 aggaagcagc tggagatcag gttgatttgt ctttattgct ggtgcatggt caggatcata
    16981 tgatgacagc cttagccttt attgatttgg ccaaggaatt ggtcgctgtt tatgacaaaa
    17041 tatcaagaat ccaaagaggt gagctatgat gatgattaca gcagaaggag atgtctctgt
    17101 cactcaatgc ttcaaggcta tactaagctc tctccaagag gattatcatg aaaacaccct
    17161 gagacggctg ccaccagctg aattaaaagc agggctaagc tacataaagc attatggcaa
    17221 aagcaaggag cataacgtta gagtgctgat cacagcctta gaagctccgc acttatatgc
    17281 tgcttgcttt agctctaatc atgggctaaa aacattaagc taccgcttag aagctctggg
    17341 agagaagcgt accaaaataa cctattgcta cgactatcag ccacttgatg tctttcaaaa
    17401 agccaatcag ctgatcattg ggaagctttt taagaagagc ttcaaacggc aatcacaagc
    17461 ccaattggca gcccttatcc aatatgctaa gcagctaagc taggggaaga tttgagtaca
    17521 gattatctgg ctgattatag ggcttatcat actaaaaaat agaaacagga gaaaattatg
    17581 tcacattttt cggataagtt tatggagatt tcaggaaaga tgggatccca gcggcatttg
    17641 gttgccattc gtgattcctt tatttcgcta atgcccatca cgatggcggg ctctgttgcc
    17701 gtcttgctga atgttttctt gcgtgatatt ccaaacaata tgggctggac tggttttgca
    17761 gcagccatgc agcccattat tgacatcaat ggttatgtgt attttgggac aattggtatc
    17821 atggcactct tttttgcctt tgcttttggg tatcatttag ctcttatgca caaggtgaat
    17881 cctttggctg gaggtttaat ctcctttgct tcctttgtcg ccacccttcc tcaaagctta
    17941 accatttcca caccacttga aggggcgtca gcaagtttat tagcaggctt aaaggatatg
    18001 ggactatcag tggtcactgc aaatggagcc cgagttttag aaacaagcca gtggggagca
    18061 attgccctca aatatgctgg agcaacaggt ctttttacag cattgatcat tggcttttta
    18121 tctagctttg tttatgcgac tttgaccaaa cgtaacctga ccatcaaatt gccagataat
    18181 gtgccacctg cggttaataa ggcttttgcg gctattattc cagggacagt cgcgatttat
    18241 gtgtcagcga tcgtagctta ccttattttt gccctcacag gctcgtctct aagtgatatg
    18301 atttcgacct atatccaatt gcctttgttg gggctgtctc aagggcttgg ctctgttatc
    18361 ctgttaacct tcttggttca attgctctgg ttctttggtt tgcatggtca caatgtctta
    18421 gcacccgtgc ttgatggtgt gtacttagtg gctctaacag aaaatacagc tgcctataat
    18481 accagtcaga gcgttgctaa tctgccttat ctctggacga gaggctcctt tgatgcctat
    18541 gcacaaatgg gtggttcagg tgttactctg gctctgatta ttgctatctt tattttctca
    18601 aaacgtgagg agcacaagac cattgccaaa ttatcagcac cgatgggcgt gtttaacatc
    18661 aatgagccaa ttacctttgg tatgcctatt gtcttgaacc caacctttgc tatcccatgg
    18721 ctaatcgtac caccaatttg tgctagcatt gcttatgctg ccacagcaat aggcttgatc
    18781 cctcccgttt tcttgccagt tccttggatt acgccagttg gactttacgc ttacttggct
    18841 actggaggta gtgttatggc aggtctggtt tccttgttta acctctttgt tgcctttctt
    18901 atctgggcac catttgtcat gtcagctaat aaagaaaaag cgagtgacct ttcatgacag
    18961 caaaaaacgg agcaagcttt ttaatggcta taggattttt ccttattgcc attagtccaa
    19021 tggttggcaa caaataccta catatcgtga caggactagc ttttgttggc ttagggtatt
    19081 atctcactaa gcgcaagcgt ccttagtcaa tgcgagcagc tagcccctat gaaaagacaa
    19141 acctaagggc tagccttgat tttctatctt ggttatcgca tttaaaagca agcaaaaaag
    19201 caagggtaga tgcttacctt tgcttttttt attttttgac ctttaataga atatcttgct
    19261 acttaaacat ttaagacctt atctaaaaat tcaattaagc gtgggtgctt agggtgatca
    19321 aagatttcct ctggagtacc gtcctctagg aattggccgc cgtctgtaaa gatcacacga
    19381 ttagccactt gacgagcaaa gcccatttca tgtgtcacaa tcagcatggt catgccctgc
    19441 tctgctaggt ctttcataac gtttaagacg tctccaacca tctcagggtc aagagcagag
    19501 gtaggctcat caaagagcat gatatcaggg ttcatggcaa gacttcttgc aattgcaaca
    19561 cgctgctttt gaccacctga tagacttcct gggaaagcgt cagccttatc agctagaccg
    19621 accttctcta gaagagcaag tcccttttcc ttagccgcct cctttgagac ctttccaagc
    19681 tcaactggtg caaaggtaat gttatcaagg actgtcatat gtggaaagag attgaagtgc
    19741 tgaaacacca tgccgatatt ttcacgagcc ttatcaatat tggtattagg atctgaaagt
    19801 tcaaagccat caaccacaac cttaccacta gtaatggatt caaggagatt gagggtgcgc
    19861 aggaaggttg attttccaga gccagatggc ccgataatac aaacgacatc accctcgtaa
    19921 aatttagcat taatgccttt taagacctca ttttgcccat aggatttgtg taaatcttga
    19981 acatcaattt ttaattctgc cattagttaa gcctcttttc taaacgtttt gcaagccttg
    20041 ttaagagtgt aatcataatc aagtagataa ctgctaggat agcatacatg cggaaggatt
    20101 gatagtttct agcgataatg attttccctg tttggaagag ctccactaaa ccgatcgctg
    20161 agactatggt cgtatccttc aaggaaatga caaactgatt gatgaagttt ggcagcatta
    20221 gcttaatggc ctgaggaagg ataatccttc gcattgttgt gtgatatgac aagcccaagc
    20281 tgcgactagc ctccatttga cctgccggca cagcctcgat acccccacga acaatttcgg
    20341 caatataggc tccaccattt agcgaaagtg caatagtagc agctacaaaa tcgttaatcg
    20401 gtgattgatg cccagtcatg ctttcaatga ggtttggcac tccccagaag ataaaggcag
    20461 caacaatcat caaggggata ccacgcacca catcaacaaa gatagtagaa gccatgcgca
    20521 ggttctttga tggggataca gccatcattc caaaaacaat accaataacc aaagcaatgg
    20581 caaaggagat gagtgtcaga ccaagggttg ttccaagccc agccaataat tgcttgtagt
    20641 tattagctaa aagtccataa atagttgact catcggctgt tttgacagat gcctctgaat
    20701 caaggtatct gctgatgatg gcgtcgtatt ttcctgatgc tttaagagca gccaaaccgt
    20761 tgttaaacat ttcgatgagc tcagggttgg ctcctttttt aacagcaaaa ccatactcac
    20821 cagaaggctc tcccttgata ggaatatcaa gcttgtggcc tcgctgaata gcgtacctta
    20881 aaatagcttc atcatccata agcccgtcaa tagaaccaga atttaagcta tcgtacattg
    20941 aggaggcctc atcaaaggct tttagacggt aaccataaat atccttgttg ctttcaagga
    21001 aatcatagga ggctgttcct tttttggcac cgactatttt acccttgagg tccttgtatg
    21061 atttgataga gcttccggat ttgaccccaa ggcgaatgtt tgatgtgtag taggaatctg
    21121 aaaaatcaaa aatctcacga cgtgcaggtg tgatagacat acctgcaata acagcgtcag
    21181 cctgaccagc ttgaacagca tttaaagcag cgtcaaagcc aggattgctg atctcaatgg
    21241 taaagccttg ctgcttagca attgccttga tgaggtccat atcaataccg acatattctc
    21301 cgctgccaat ttgaaattca aagggagcaa aggaggagtc agccacgatt ttataaaccg
    21361 gctttaaagg agtggcctta gcagaggcat cgccagtagc cttgcctgct gtgaccttgt
    21421 cattgctgcc aagccatttt gtcatgatag cttgataggt tccatcagcc ttcatagcgc
    21481 ctaaggcttc attgaagtcg tcaatgagat aatcatagcc gctgcctttt ttgacagcaa
    21541 agccaaagct tccaatagcc tctcccttca tgttgatcgc aagatcctgc ttttggttaa
    21601 tggcatattg aatgacaggc tcgtcgtcca taacagcgtc aatagagcct gttgcaagac
    21661 tgttgtacat caggtcacct gtgtcaaatg ttttaacagt ataaccatac gattttttgt
    21721 atttatctaa gaaggcttga gcagctgttc catttttaac accgactgtt tttcctttta
    21781 gctcgctata tttcttaata gggttagcct ttcttgtagc aataacaatt tttgtatcgt
    21841 aatagggatc tgaaaaatgg aagacctttt gacgagcagc agtgatggtg gtgcctgcca
    21901 taagggcgtc agcttgacca gactgaatgg cattgacagc agcatcaaag ccagggaatg
    21961 tcatattgat attccaaccc tttcgctttg ctacttcatt gatgatgtca acatcaatcc
    22021 ccttatacac ctgatctgaa tccttgaatt caaacggtgc ataagcagta tcagaaacaa
    22081 tatcaattgt ctctgcactt gcaatcccag cagtcatcaa aacaactgac agcattgcaa
    22141 gcatccatgc ttttaatgtg tttttcatac tagtctcctt aataaaaata aaaaatatgc
    22201 ctaattatag cagatttttt tcaaacaagc aaatcatctc ttctttttat gtcataaaac
    22261 ctaacataaa caactaaaat agtcaaaaag ctttgataga gtctttaagt ccttaactat
    22321 gttacaatag ataagagata agatattgag gaccaataaa tgattgataa acgtgatttt
    22381 aaagcattta agctcgtgtc aaaatatgcc ccctcaggag atcagccgca ggcgattgag
    22441 accttggttg ataacattga aggtggtgaa aaagcgcaga ttttactagg agcaacagga
    22501 acagggaaaa cctataccat gagtcaggtg atcagcaagg tcaacaagcc aacgttagtg
    22561 gttgctcata acaaaacctt ggccggtcaa ttgtacggtg agtttaaaga gttctttcct
    22621 gaaaatgctg tcgagtactt tgtatcctac tatgactatt atcagcctga ggcctatgtt
    22681 ccttctagtg atacctatat tgaaaaagac agctctgtta atgatgagat tgacaagctg
    22741 cgccattcgg ccacctcatc gcttttagag cgtaatgatg tgattgttgt ggcttcggtt
    22801 tcttgtattt acggattggg ctcaccaaag gaatatgctg attcagctgt tagcctgcgt
    22861 cctgggcagg agatatccag ggatcagttg ctcaatgccc ttgtagacat tcagtttgaa
    22921 cgcaatgaca ttgattttca acgtggacgc tttcgtgtgc gtggtgatgt ggttgaagta
    22981 tttccagcct caagagatga gcatgccttt cggattgagt ttttcggtga tgagattgat
    23041 cggattcgtg aaattgaaag cctaacgggt aaagtattag gtgatgctga tcatttagtg
    23101 ctttttccgg ccactcactt tgtgaccaat gatgagcaca tggagcagtc tattagcaag
    23161 attcaggcag aattagcaga ccagcttaag ctatttgaag cagaaggcaa attgctagag
    23221 gctcagcgcc tgcgtcaaag gacagaatac gatattgaaa tgctacgtga aatgggctac
    23281 accaatgggg ttgaaaatta ctcacgtcac atggacgggc gttcggcagg agagcctcct
    23341 tataccctgt tagatttctt tccggatgat tttcttatca tgattgacga gagtcacatg
    23401 accatgggac aaattaaagg catgtacaat ggagacaagg ctagaaagca aatgcttgtg
    23461 gattatggct ttcgtcttcc gtctgcctta gacaatcgtc cgcttcgtcg ggaggagttt
    23521 gaaagtcatg tgcaccagat tgtctatgtc tcagcaacgc ctggagatta cgagatggag
    23581 cagactgata cgattgtgga gcagattatc agaccgacag gtctgcttga tccggaggtt
    23641 gaagtccggc caagcatggg acaaatggac gacttgcttg gcgagattaa cctgagggtt
    23701 gaacgaggtg agcgcacctt tatcacaacc ttaaccaaga aaatggcgga ggatttgacc
    23761 gactacctca aggaaatggg tgtcaaggta aaatacatgc atagcgacat caagacatta
    23821 gagcgtacag aaattattcg cgaccttcgt ttaggcgttt ttgatgtctt gattggtatc
    23881 aatctgctgc gtgaaggtat tgatgttccg gaggttagcc ttgttgctat tcttgatgcg
    23941 gataaggaag gcttcctaag aaatgaacga ggtttgattc agacgattgg tcgagctgcc
    24001 agaaatgctg atggtcatgt gattatgtat gctgatcgta tgacggattc catgcagcgc
    24061 gctatagatg aaactgctcg tcgtcgtgcc atacagatgg catataatga agagcatggg
    24121 attattccgc aaaccattaa aaaagatatt cgtgatttaa tcagtatttc cagagcagtt
    24181 gaagcaaaag caacagaagc agagacaaat tatgagtcaa tgacgcggtc tgaaagacaa
    24241 gaagctatta agcaattgca aaaaaacatg caggaagcag cagagctgct ggattttgaa
    24301 ttagcagcac agcttcgtga cctgatctta gagttaaaag caatggatta agacctgata
    24361 agctaagtct ggctgtataa gctaggcttt ttatctgctt ttgagtttgt cctttaggtc
    24421 tgtcttatga tctttggtac cagataaatg agtgatatct tgagcttgat ctacgcaaga
    24481 gctagtgcag ccactagctt cagactactt taatgattta atgaaagatt gattttgata
    24541 agacaattct gatataatgt aaagtagttg gcaaaaatag aaacattaaa taaattttct
    24601 ttttaataat ttaactttta ccttgtcaac aaggctattt tcggatagaa tttcttagta
    24661 cattatttca ctaatacaag aaggtaagta tgttaaaaaa caagtcaaga ctgcgagcta
    24721 ttttcgtttt tgttgggaag atagcgttgt tttacgtgat tttgatgctg ctcgtttatt
    24781 tttttggtta cctagggcat ggtcaaagta attttattta taatgaattt taggagattg
    24841 tctgatggtt aacgatatga ttgaaacaat tgagtatttt gcacaagcac aaccggattt
    24901 tccagtttat gattgcttgg gagagcgccg tagctatggg cagctaaagg aggactcaga
    24961 tagtattgca gcccttattg agagcttaaa gctaggtgaa aaatcacctg ttttagtttt
    25021 tggggctcaa agctatgaca tgctggcttc ctttgtcgcc ttgacaaaga caggtcatgc
    25081 ttacattcct gttgatgttc attcggcgcc agagcgtgtc ttgtctatta ttgagattgc
    25141 tcagccaagt cttatcattg ctattgagga gctgccggtt agtattgatg cgattagggt
    25201 ggttagctta gcagagatag aggcagctaa agcagccaag gcagccttta ccatgaccag
    25261 tcctgtcaag ggagatgaca attattatat tatcttcacc tctggaacga caggacagcc
    25321 aaagggagtg caaatttcgc atgccaatct tttaagcttt accaattgga tgattgagga
    25381 tgctgagttt gctattcctg agagaccaca gatgctggct cagcctcctt attcctttga
    25441 tttgtcggtg atgtattggg cgccgacctt agctttaggt gggacattgt ttgctttacc
    25501 caaggaaatg gtttcagatt ttaagcgctt gtttagcaca attgcggagc tgccgatagg
    25561 gatttggacc tcaacaccgt cctttgccga catggcaatg cttaatgatg atttttgtca
    25621 ggagaagatg ccaaggctga cccactttta ttttgatggg gaggagctga cagtatcaac
    25681 tgcaagaaag ctatttgaac gctttccaga cgcacgcatt atcaatgcct atggtccaac
    25741 agaggcaacg gtggcgttat cagcgatttc aatcactaaa gatatgatag agacttacac
    25801 acgcttgccg ataggctatc caaagccgga ttcgcctact tatatcattg atgaagctgg
    25861 caatgctctg gagccggggc aacagggaga gattattgta acgggtccag cagtttctaa
    25921 gggttatctc aacaatcctg aaaagacagc tgaagccttc tttaccttta atggcatgcc
    25981 tgcttatcat acgggagatt taggatcatt tactgaggac aatgtgttac tttatggtgg
    26041 acgattagac tttcaaatca aatatgcagg ttaccgcatc gaattagaag atgtgtcgca
    26101 gcagctaaac caatcaccgc tggttgaatc agcagtagca gtaccaaggt ataacaaaga
    26161 gcataaggtc caaaatctct tagcttatgt tgtcttgaag gacggggtga gggagcaatt
    26221 tgcgagagat ttggatatta ccaaagccat taaagcctct gttaaggatc atatgatggc
    26281 ctatatgatg ccgtctaagt ttatttatcg tgaaaagctc ccattgacac caaatggcaa
    26341 aatcgatatc aaattcttga ttaacgaggt taatcatcaa tgacgacctt gtttcatcac
    26401 ataccttata tggagcctta tggcaatccg atttattttg tctacctcat cattgctttt
    26461 cttccagtta ttattgggat ctttaagcaa aggcgttttt cgacgtatga aagctttgtc
    26521 agcctgatct ttattttgct catgtttggt ggagagcact atcagcaatt gcttgccttt
    26581 ttagcctatc taatttggca aaccatcagt gttttggctt acaagcacta tcgtcaaaag
    26641 gcaaatgcag cgtgggtttt ctatcttagc attttagcca gtctatttcc tttgatttgt
    26701 gtgaaggtaa gcctcagtct aacgaggtct ttctttagct tcttaggtat ttcctattta
    26761 actttcaaaa gcgttgggat gatcattgaa atgcgtgatg gggttttgac agattttagt
    26821 ctaaaggatt ttctacgctt tatgattttc tttccgactt tttcaagcgg gccgattgat
    26881 cgcttcagaa ggtttcaaga ggcttacacc aagcttccta gtcgtgatgt ttaccttgat
    26941 atgctcaata aggctgtcat gtatctcatg ctgggctttc tgtacaagca tattatctct
    27001 tattgcttgg gtgggctgct attgcccctt gctgaaaata aggctctgac tgtaggtggc
    27061 tactttaata aagagacgat ctatgtcatg tacctttatg ggcttaatct cttttttgat
    27121 tttgctggct actcgatgtt tgcgattggg ttgtcttatt tactggggat taagacacct
    27181 gaaaatttca ataagccctt cttatcacca aatttaaaag agttttggaa cagatggcat
    27241 atgagcctat cattttggtt tagggatttt gtttttatgc gattggtcca tctattgatc
    27301 aagcacaaga cctttaagaa tcgaaatgtg acttcgggct ttgcttacct gatcaacatg
    27361 ctggtgatgg gactttggca tggcttgacg tggtattata ttgcttacgg tctgtttcat
    27421 ggtattggct tgattgtaaa cgacgcttgg cttcgtaaga aaaaggaaat caatcgtcgt
    27481 cggaaaaagc aagggcttaa gcctttgttt gagggtaagg tatttcatgc tttatcaatc
    27541 gtggtcactt tccacgttgt cttgttctca cttctgttat tctcaggctt cttaaatgag
    27601 ctttggttta gcagaccgtt acgttaaaaa aggagagtat aaaaatgtct actaaagaaa
    27661 ctgtaattga cttatttgat cgcttgttta tggaagacgt atcagatatg atggacgagg
    27721 atttgtttga tgctggcgtt cttgatagcc taggaacggt tgagctgatt gtagagatcg
    27781 aatctatctt taacattaag gtgccaattt cagagtttgg acgtgaggac tggaacactg
    27841 ccaataaaat tattcagggc atagaggaat tgcagcatgc ttaaacggct ttggttaatc
    27901 ctaggtcctc taatcatcgc ttttggcttg gtttgtctta ccatattcag ctttcctact
    27961 aagcttagct attcattgcg ccaggaaaag tcaaatgcag tggcaatcaa tgatagctcc
    28021 tttaaaaacg gcttgattaa aaggcaggcc ttgtcagatc ctaactactg ttttgttccg
    28081 ttttttggct ctagcgaatg gagtcgcatg gatagcatgc acccatcagt gcttgcagaa
    28141 cgctacaagc gctcctacag accgttttta attgggaaaa gaggctctgc ttccttatca
    28201 caatattacg gcatgcagca gatttcacag gaaataactg gaaaaaaggc agtctttgtc
    28261 gtgtccccac aatggtttac cccccaaggc attgatcctg gtgcggttca attgtatcta
    28321 tctaatagtc aggtgattga tttcctctta aaagcaaagg ctagtcataa ggaatcacaa
    28381 tttgccgcta aaagaatgct ggacattaat ccgggagttg ctaaatcaga gcttttaagg
    28441 aaaattagtc aaggcaaggc cttgagtaga tgggacattc gtctgctcaa atggcagcag
    28501 gagctgtcct taagagagga gtccttgttt agcttccttg gtcgttcaac aaactatgag
    28561 gataggattt tgcctcgtgt taaagggttg cctaaaacct tttcttatga gcgcttgagc
    28621 gagctagcag ccagacgggc taaggaagga acttcaaata atcgctttgg catcaaaaat
    28681 gctttttatt ctaagcgaat tgcaccgcaa tttcctcttt ataagaattt tcagtgccgt
    28741 aataattaca ctgtgtcacc tgagtacaat gattttcagc tggtattgtc agaatttgca
    28801 aaacgtaaaa cagaggtgct tttcgttatt acacctgtta atcaagcgtg ggcaaattat
    28861 acaggcttaa accagaggag gtatcaaaag gctgtcagaa aaataaagca tcagttaacc
    28921 tcgcagggct ttactcgcat tgctgatttt tccagaaatg gcggagacaa gtattttatg
    28981 gaggatacca ttcaccttgg ctggaatggc tggctagcct ttgacaagga ggttgttcct
    29041 ttcttagagg atcaaacacc accatctgaa taccaactgg atccttactt cctatcaaag
    29101 gactgggcag atagaacagc aggattttag ggtcaataga ccattagaaa atgaggatta
    29161 gaattgttaa tgagtatcat cgtcatattg cttattttag ccattgctgt tttagtgatt
    29221 gagtatggtc aaaagcggtc cttttctagc tggctgcttg aaaagatgtt tgattatcgt
    29281 aagtataagc tctctaaaaa ggctgatgac tatgaaggaa ttgagacgca aagacgtcgt
    29341 cgcattccct accacttgga taatccagag gcggtattgg ggattcccac cacagaatat
    29401 acgattgatg gcatgcaggt ttttgtgatc aatgaccaag attctcagga tcagccagtg
    29461 atttactatc tttatggtag tgtctatttg cgtcgacctg agacatttca ctttaaaacc
    29521 attaagcatt tgatccattt aaccaatgcc aagctggtgt tcccaaattt tgagaaggcg
    29581 ccttatgtca cctataagga gatttaccca aagcttgcta aaacttatca ggagctttgt
    29641 ctagccaatg gcgctgccaa ggttagcatt attggtgact cctcaggtgg tggcatggcc
    29701 ttagccttgg cgcaatacct aagagatacc caaactgcac cacagccaaa gcaattaatc
    29761 ctgttatctc cttggttaga tgttagcttt gctaatcagg attataagca ttttgaagca
    29821 gtagaggctt atttagatgc taggcggctt cgagacattg gtgaattgtg ggcaggcagt
    29881 ccagaagaaa tgcggtctcc gtatgtcagc ccattatatg gcgattatca tgacctgcca
    29941 aagattgtca cttttgtcgg gacaaaagag attttttacc cagatattat gaccctgcat
    30001 gagcgcttga tggagcaagg gcacttaaat cagctcgtta ttgctgagca gatgattcat
    30061 gcttatgcga tcttcccgat acgagaggca aggcaggcgc gcaagcagat tgccgagctg
    30121 attttaaaga aggagtgatt gttgctatag gagtcagtta gccttgcttg tctgatgagg
    30181 cttgggcttg agatttctag agaagcttta aggcctttac ttgggctgtt aatgctcatt
    30241 aaagaggatt ataggcttta tactagggct taggattgct gttttgctat tcaataatat
    30301 tagtttagac ttgattgagg aaaggctagt tttagttatg gtcctcaatc tttttttgat
    30361 ggtaaacatg tcaagacagt ttacttgcta gggtaataat cctgtgctca tttcatgagt
    30421 ggctattttt atcctaagct tggtggtgga aaaatcagat taaaaaatat gaaatttgct
    30481 attgacagct gtaagcgatt gcattataat aaacttaact taaacgttta agttaagttg
    30541 aataagctga tttgatcatg cactgcctaa atgcaatcaa taatctcaaa gcatttggtg
    30601 tagtctagta atcaatgagg cagtttatta cggttataca atatttattt agttcatccc
    30661 tttaggaggt aaatagctat ggcgtgggat tggaaaaaag caggtgttgt tggagtagtg
    30721 tcattggctt cgatcatggt attaagtgct tgtagcggag gacatcaaaa agaggctaag
    30781 caaaaagacg acaataccat tgtagtttca gttgatgagg gctatgcaga ctacatcaaa
    30841 gagattaaga cagcctttga aaaggacaat aaggtcaagg tcaaggtcaa aaaggaaggt
    30901 atgattgata cgctagataa gctatctact gatggaccga caggtgcttc accagatgtc
    30961 tttttagcac catatgaccg ggttggtggg cttggctctg aagggcaaat tgctgaggtg
    31021 agcttaggca atgctgacca gtttgatgac actgttaaaa agctagtcac cataaatgga
    31081 aaggtttatg gggcaccaga tgttattgag accttagtga tgtattataa caaggatttg
    31141 gtatcagagg ctccgaaaac ctttactgac attgaagagc taaataagga tcctaagttt
    31201 gcctttgctt ctgaagacgg taagtctgta ggctttcttg ctaagtggac agacttctat
    31261 tatggctatg gcttgattgc aggctatggg gcttatgtat ttggagataa gggaactgat
    31321 ccaaaggatt taggtattgg taatgctggt gccattgaag gcttagacta tgctaagaaa
    31381 tggtatagcg tatggcctca aggcatgcag gatactcaaa aggctggaga ttttattaca
    31441 gagcaattca cctctaaaaa ggctggtgtg attattgatg gaccttgggc tgctgcctca
    31501 tttaaggagg ctggtgtaaa ctttggagtg gcacaaattc caagcttacc taatggcggt
    31561 agctatcaag cctttggtgg tggtaaagca tgggtgattt caaattattc taagaataaa
    31621 aagctggcac agcaattcct tgattatgtg acaaatgaga aaaaccaaaa agccttttat
    31681 gataagacac aagagatccc tgccaatcta gctgctcgca gctatgctgc agaacaagga
    31741 aatgaattga caaaggcggt tattgggcaa ttctcaaatg ctcagccaat gccaaatatt
    31801 ccagaaatgg cagaagtttg gggaccaggt gcgaacatgt tctttgaggt agcagcaggc
    31861 aagaagactc ctgccaaggc tgctaaggaa gcagctaaaa ccattcaaga ggctattgca
    31921 caaaaataca ctgaataaca taaaaaggga ggctgggata aaggtatcct agtctccatc
    31981 ttgttaccta tagtatcaga gtgggcgatg aggagataat aataaaaagt agtagtgact
    32041 agcttgtctt gtttcccatc ttgtcctaat aagagtatct gataagactg atgaacctag
    32101 ggaggaaaaa atgaacacag ccggaatact gcatattcca gattctagat attgctttgc
    32161 cttatcaaca aaggagcttg tgattcggtt gagggttgca aaggaggata acgatatagc
    32221 ggtgacgctg gtttatggac ctaagtatca ttatcatgag tatcaaaaag aactggcgat
    32281 gtatgctgct tataccgatc atacccatac ctattatgaa atcaccttaa gtcttgatga
    32341 tgttagattg gcctatattt ttaagcttga gcaatctggt cacacctatt actttagtga
    32401 ggatggcttg accacaagct atgatttttc aaatggcttt tacaactttt ttcaaatgcc
    32461 ttatattaat gctgtagacg ttcatcagac tgtcccttgg gtgcacaatg ctgtttttta
    32521 tcagatcttt gttgatcgct ttcatcgtgg tgactttgaa aaggacgata gctatattaa
    32581 tatggcttgg ctggataggc caactcctaa tagctttgcc ggaggggatt tgaaggggat
    32641 tacagataag ctggaatacc ttgaggatct tggtattaat gtcatttact tgacaccgat
    32701 tttcaaatcc atcagtaatc acaaatatga tattagtgac tactatgcta ttgacccgat
    32761 gtttgggaca tcgcttgatc tccagcaact aataaacgag gcccaccaaa gagggattag
    32821 aattatttta gatgctgttt tcaatcatgc tagcagtgat tgcgagccat ttcaggacgt
    32881 tttggcacat ggtagtgctt cttcattttt tgattggttt atgattcaag gagatcatcc
    32941 ttctgtagag ctagctaatt acgaaacctt cgctgattgt cactacatgc ctaagtggaa
    33001 tacctcgcat caggctgttc aggattattt gattgagatt ggtctttatt ggatcacaga
    33061 gtatcatatt gatggctggc gattagatgt ttctgatgag gtatcgcatg atttttggag
    33121 acgctttcga aaggctgtta aggcagtcaa atcagatgcg atacttattg gagagaattg
    33181 gcatgatgct tatccctacc ttcaaggaga ccagtatgat ggtattatga attacgcctt
    33241 taccaaggct tgtctcgatt attttgcatt tgatgcgatt agctcacagg aaatggctga
    33301 aagattgtcg catattttaa tgagaaatac ttggcaggtc aaccagatga atctgaattt
    33361 actggattcc catgatacgc atcgcttctt gactcaggtg aatggctcta aggacaaatt
    33421 attggctggc ttagcccttt tagttacctt tatgggcata ccatgtattt actatggaac
    33481 agagcttgcg atggagggag gttatgatcc tgactctaga cgtagcttta attgggacag
    33541 cagcacttgg gatatgagct tttggaatca ggttaaggac attatcagcc tgcgtcgtca
    33601 tgcggttatc caatttggaa gcatttcgat aacctcccat gatgactgcc tttgcgtaaa
    33661 gcgtgaatta aacggtcaat cgataagatt gctggttaat aatggcgtta agccatatcc
    33721 tattgagaaa ggaggttctg tgcttgtttc taatggtgta gataaagaga catttgagct
    33781 actccagaac gggtttgttg ttagctatta atatggcgtt ttatcaaagg aggttaagga
    33841 tgaagcgtat tactttaaca tgtcgtaaag cattaacagt agctatggca gcggttacct
    33901 tagcaatgtc aactaacagt gtctttgcta ttgaaaatac tgcggtgtct aataaggctg
    33961 atttttctac tgacacgatt tatcaaattg tcaccgatcg ttttcatgat ggtaatgctg
    34021 ctaataatgg aaatacagat gtatttgata aaaatgatcc taaaaaatat catgggggtg
    34081 attgggcagg tatcattaag aaactagaag atggctactt aaccaattta ggggtatcag
    34141 ctatctggat ttcatcacca gttgaaaaca ttgataccat tgacccttca aatggcagtg
    34201 cagcctatca tggctactgg gcaaaggatt ttttcaaagc aaacagtcac tttggaacaa
    34261 tggaggattt taaaaagctc attcaggtgg cacatggcaa aaacattaaa gtagttattg
    34321 attttgctcc taatcatacc tcaatagcag aatataatgg cttaaccttc cctgaggacg
    34381 gtgctttata taaggacggc cagctggttg gtaaattcag tcatgatgat caaaagattt
    34441 tcaatcatga atcatggact gatttttcaa cttatgaaaa tagcatttat cattccatgt
    34501 atggcttggc agacttgaac aatctgaatc caacagttga cgattatctc aaagaggcta
    34561 ttgataaatg gttagaaatg ggcattgatg gtattcgtgt agatgcggtc aagcatatgt
    34621 cacaaggctg gcaaaaaaat tggttgagtc atatctatga gaagcataat gtattcgcct
    34681 ttggggaatg gtttgctgac ggttctttta atgatccatt gatgactaaa tttgctgata
    34741 ctagcggcat gagcctgctt gattttaggt ttgctaattc tgttaggcgc ctgtattctg
    34801 atttatcagc gaaaatgcaa gatttttaca atatgattgt agctacggaa aaagagtaca
    34861 aggaagtttc agatcaagtg actttcattg ataaccatga tatgacccgc tttgctactc
    34921 tagtcaatca taatcagaca gctgttaatc aagcctatgc tttactgcta acatcgcgtg
    34981 gtgttccgaa tctttattat ggttcagagc agtatgctac aggtgctaac gaccctgaaa
    35041 atcgtggtga tatgccaacc tttgataaga attccactgc ttatcaggtg attagcaaac
    35101 tagcaccact gcgtaagaaa aatcaagccc tggcttatgg tacaacacag cagcgctgga
    35161 ttaatgatca ggtcttggcc tttgaaagaa aatttggaaa tgacgttgct ttagtggctg
    35221 ttaataagga tcaaacaaat ggctacacaa ttagtggcgc taaaacggct ttaccagctg
    35281 gtaagtatgc tgatgaatta ggtggcttac tgggcggaaa ggaattaacg gtatcagctg
    35341 atggtaatgt tgaggcattt gagttaggtg cgggtcaggt tgcagtttgg acctttaaag
    35401 ggcaacatga gacaccgcag ataggagacg tagacgcttc gtttggcgtt gcaggaaata
    35461 ctgtctctat ttcagggcaa ggatttggta gtgctcaagg tcagcttcat tttggtgata
    35521 gcaaagcaga tattgtgtca tgggacgata ccttgattca atttaagata cctgctgtag
    35581 ctgctgggaa ccatgatatt aaggtgacca catctacagg acaaagcagt agcccttaca
    35641 aagcctttga agtgttaaca gataagcaaa ttccagtaag attggtggtc aataatttca
    35701 acactgtatt aggtgagcag ctttatatcg ttggtgatgt ggttgagctt ggggcaaatg
    35761 ataatcataa agctttaggg cctattttta atgcaacaca gtcaattgcg cagtacccaa
    35821 attggttcta tgatgtcaat ctgcctatta acaaaaccat taactgtcat cttgtaaaga
    35881 aggatagttc tggtaaagta ttgtggacta gtccagaaac ctataccatt aaaactgata
    35941 gcaaggctca aaccatttca ttgaaaaaat agttgcgtta tctgtgatgt tatttaatac
    36001 tctatgaagg aggagaacca taaaagggtg atagagagga atgacaaatg cttaagaatg
    36061 aaaaaatgaa gaatccacaa aaagccatgt ggctttcaat aatccctggt ctggggcaac
    36121 tctacaatac tcaaaaggta aaaggcttta ttttgcttct tgtgttttta ggtgagctgc
    36181 tagaggcttt ctttgttggt attccggctc ttgctggctt gtacagcctt ggtagtgtac
    36241 caatggagga tcattcccta ttcttattga ttaagggagc tatgcagctt atcctatttg
    36301 ccttgttttt gatctttcat ttggctgcta tgcgagatgc tagactagtg gcaagggaga
    36361 tcaatgcagg ccatagcatt tcattaacct taaaggagat ggtacaatcc atctatgaaa
    36421 agggctttcc ttatttgctg attattccag cctacttggc catggccttt gccattgttt
    36481 ttccggtgct tgttacttta ttaattgcat ttacaaacta tgattttagg catattcctc
    36541 cctataaatt attagattgg gttggcatta agaattttaa aagcatttta gagcttagca
    36601 cctttaagtc agcctttggc tctgtgctgt catggacctt gatttggacc ttggcggcaa
    36661 cgagtctcca gattgtgata ggaatagcga ctgctattat tgccaaccag tcctttgtga
    36721 agtgcaggcg catttttggg gtgattttct tgctgccttg gggggtgcct gcttttatct
    36781 cgatcatgag ctttggtaat ttctttaatg attctatcgg tgctatgaat gttcaggtct
    36841 taccattttt agaaaagttt gtgccatttg cagattttgg gattatccca tggaagacag
    36901 atcctttttg gacaaaggtt gcggtgatta tggttcaggg ctggctgggc tttccttata
    36961 tttatatttt ggtgtctggt attttacaat caattcctgc tgatttgtat gaggcagcaa
    37021 cggttgatgg tgcaacagcc ctgcagaagt ttcgccaaat taccttgcca atgatctttg
    37081 ctgtcgcagc cccgacctta atctcgcagt atacctttaa ttttaataac ttctccatta
    37141 tttatctctt taataatgga ggtcctggta cagttggcgg tggcgcaggg tcgacagata
    37201 ttttgatttc ttggatttac aagctgacca cacaaacgtc accacagttt tccattgctt
    37261 cagcggtgac cttaatcatt tccttgattg ttatttctgt atcattgata acctttaaaa
    37321 aattcaaagc ctttgacatg gaggatcgct aaatgggtag gaattatttg ccacagtcag
    37381 tgaagaagaa gcgcttgtta gctcagctgt tgacttacag ctatttgcta atcctgtcga
    37441 tcatcatctt atttccaatc ttggtgaccg ttagctcagc ctttaggcca ggaaatacaa
    37501 ctgcctttag ctttcatatt gatgggcctt ggaccttatc aaactttgag acactctttc
    37561 aggacaccta ttacttaaga tggtactgga acacgttagt tgtcgccttt ttcacgatgc
    37621 tgatccaggt gacagtcatt acgctgacag gctatgctta cagccgttat cacttttttg
    37681 ggcgtcaaaa gagtttggtc tttttcttag tggttcagat ggttccgaca atggctgcct
    37741 taacagctta ttttgtgatg gcttggttgt ttaatgctct gaatcactat tggttcctca
    37801 ttctgattta tgttggagga ggcattccga tgaatgcttg gttgatgaag gggtattttg
    37861 atactgtgcc ttatgattta gatgagtcag ctaagctaga tggctctggt cactttagga
    37921 ccttctacca aattgtattt cctctggttc gtcctatggt tgctgttcag gccctatggg
    37981 cctttatggg gccatttggt gactttatgc ttgctaagtt tctcttgcgt gaacaggagc
    38041 attacaccgt agcggtaggt cttcagtcat tcatcactaa cgacgctagg gatcctaagg
    38101 tcacattgtt tgcagccggg gccattttaa ttgcagtgcc aatttcagtg ctattcttct
    38161 ttttacagaa gcattttgtt tcaggcttaa ccaatggtgg aacaaagggt taatttatct
    38221 ttcaaggagc ctttatcatg actaatgatc gatttcctat ttcttacaca accattattt
    38281 tttctcctaa aatgatattt gctcgttgca gtgccttttt gtggtggcag aatgtgattt
    38341 tagtgatctt tctaaatgct ctggtgttaa tgccgatcac gctgcattat gcaagcttga
    38401 agagctatcc cttagagcac atagttagta atggtttaga ctccttgaca gaaaaaacct
    38461 atcatgcctt gacacaaggc actatttggc atgatcgcta tgatggaaaa acagtcctta
    38521 tagaggatac tgatgctgtt gttgctgtat tgccaacacc agaaatagta gaagagctaa
    38581 agaaagatca aagaagccag ctgatattaa cagaaacctc atggatttta agctttcctg
    38641 atggtcaaag gctaactgct aaggttaaag gcaacaagga aaggctaacg cgcttaacct
    38701 ctctagaggc tgtcaaggcc tttgttaatc agcaatggta caatagcaat cgtgccgctg
    38761 tgcttgcctt tttgctgcta gtggctagca gtgtggtcta tctaggagcc ggtttagtga
    38821 tcggaattgg ctcgttatca ctgttattaa caagatctgc tagattattt tcactcaaga
    38881 gctactcaga atgcttgggt ttgctagtga attgctttgg acttcctacg cttttagcag
    38941 tgcttataag tttttgggtg cacaatccta ttgttatcat gaatagtcag gtctttggca
    39001 cactgctcat gctggttcta gtcttttaca aaactcagtt tagagatgag gagcaagcac
    39061 tagcttagcc cttgctgaca tcaaaaaatc cctc
//
LOCUS       DARYNN010000016        38646 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.016, whole genome shotgun sequence.
ACCESSION   DARYNN010000016 DARYNN010000000
VERSION     DARYNN010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38646)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38646)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38646
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.016"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(482..2272)
                     /locus_tag="TVB59_000759"
     CDS             complement(482..2272)
                     /locus_tag="TVB59_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-hexosaminidase"
                     /protein_id="HEL1009685.1"
                     /translation="MTHLVDLRKKPYSLDEEAICWVEDTIAAMTLEEKIGQLFVNMGA
                     SRSEDYLTQVLEDYHIAAVRYNKGMASEIWDQNYILQTKSKIPMLIAANTEAGGDGAV
                     NDGTKVGDEIKVAATNDPKYAYEMGRIAGLEASAVGCNASFAPIVDLTRNWRNPIIAN
                     RNWGVNVDQIIELSKEYMKGIMEYGIMPFAKHFPGDGIDERDHHLSFASNPMTKEEWL
                     SSFGRIYGELAEAGLPGIMAGHIHLPNVEKAMHPERELDDMLPASLNKTLLDELLRGE
                     LGYNGAIVTDASHMVAMTASMPRRLLLPTAIEAGCDLFLFFNDPDEDLQWMKEGYEAG
                     ILSDERLHDALRRTLGLKAKLGLHRFEGHREDIMLPKDKAMVLINTPEAQAIADEVAD
                     KAITLVKNKQAGIFPVTPERYKRVLIVNVEGYKGGFGAMIAGQKKRASDIVKELLEAR
                     GHEVTVWESTEERIMQLPEEERAAAIANVYAQKQPISNITEHYDLILNLVDVNSGGTV
                     QRIIWPAAKGTPDQPFYVHEVPTIVVSVQHAFALADMPQVGTYINAYDGKDNTMKALV
                     AKLAGESEFTGVSPVDAFCGLIDTQLWHSF"
     gene            complement(2387..3190)
                     /locus_tag="TVB59_000760"
     CDS             complement(2387..3190)
                     /locus_tag="TVB59_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEL1009686.1"
                     /translation="MTAKTEQFVFCVDSDGCAMDTMTYKHQLFFGPLAADYFAVADQA
                     SFLKEWDRINLYSRTRGVNRFVGLVMGLEYAGVTGIDALKQWVQHTASLSNQSLEAEL
                     LKRPSDDLQKALDWSNEVNRQIEAYKGEALAFLGALAALKALHQLGQVFVVSSANKEA
                     VQKEWQDQGLMTHVDGLYCQDRGKKEAVIAQLIDEGYVRERMMMIGDSPGDLAAAEQN
                     QITFFPILVGKEASSWQDLSHAAEAFTTGDLTELDVKSLTEAFWRNLDR"
     gene            complement(3454..4293)
                     /locus_tag="TVB59_000761"
     CDS             complement(3454..4293)
                     /locus_tag="TVB59_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000047575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEL1009687.1"
                     /translation="MSRVIEFKDKVVVITGAGGVLCGSMAKAFAKAGAKVALLDLNQE
                     AAQAFVDDIEAEGGIAKAYQANVLSKENLEAVRQAVLADFGPADILVNGAGGNSPKAT
                     TDNEFHDTSLPEDTKTFFDLDEAGISFVFNLNYLGTLLPTQVFAQDMVGRKGANIINI
                     SSMNAFTPLTKIPAYSGAKAAISNFTQWLAVHFSKVGIRCNAIAPGFLVTNQNRSLLF
                     TEDGQPTARAEKILKNTPMGRFGEAEELIGGLFFLADEQSASFVNGVVLPIDGGFAAY
                     SGV"
     gene            complement(4309..5403)
                     /locus_tag="TVB59_000762"
     CDS             complement(4309..5403)
                     /locus_tag="TVB59_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HEL1009688.1"
                     /translation="MKMSFRWYGKHDPVSLEEIKAIPGMQGIVTAVYDVPVGQAWPLE
                     NILELKRIVEAAGLEISVIESIPVHEDIKQGKPNRDELIENYKTSIINVGKAGIPVVC
                     YNFMPVFDWTRSDLNYPLPDGSTSLAFLKADLADVDPVADDLNLPGWDFSYSKEEMKA
                     IIEHYRHHISEEDLWANLDYFIKAIMPTAEAAGVKMAIHPDDPPYGIFGLPRIITGQK
                     AVERFLDLYDSPNNGITMCVGSYASDPQNDVIAMTEYALKRQRINFMHTRNVTAGDWG
                     FQETAHLSQAGDIDMNAIIKLLVDYDWQGPLRPDHGRRIWGDQTKTPGYGLYDRALGA
                     TYFNGLYEANMRAAGKIPDFGITVKTVGDK"
     gene            complement(5665..7062)
                     /gene="uxaC"
                     /locus_tag="TVB59_000763"
     CDS             complement(5665..7062)
                     /gene="uxaC"
                     /locus_tag="TVB59_000763"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HEL1009689.1"
                     /translation="MAFNDDNFMLKNEAAKRLYQQIKDQPIFDYHCHLDPKEIFEDKV
                     YDNIVDLWLGGDHYKWRLMRANGISEEEITGSASKLDKFKAFARTLQRSYGNPVYHWS
                     VMELKNVFGVCELLTEDNAEEIYHRINAYLVEHQISPRKLIADSRVRFIGTTDHPLDD
                     LAWHKRLAADDTFETVVAPTFRPDEAFIEHQRFADFVARLAQATGRTITDFKSFIAAM
                     EERIAYFAENGCKASDISFTEIVFEAAEPEQLDRLMTRVLEGYQPQPLEVKQWQTAVF
                     AELCRLYKHYGFVTQVHFGALRNNHSAIFNKLGADVGVDSLGDQTGLAINMNRLLDHL
                     VQRDSLPKMIWYNLNPSYNIAVANTLANFQANENGIAGYLQFGAGWWFADTKLGMISQ
                     MNALAEQGLLANFVGMLTDSRSFLSYQRHDYFRRILSTYLGEWIEEGEVPEDYQALGK
                     MAQDIAYNNAIQYFN"
     gene            complement(7090..7707)
                     /gene="eda"
                     /locus_tag="TVB59_000764"
     CDS             complement(7090..7707)
                     /gene="eda"
                     /locus_tag="TVB59_000764"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEL1009690.1"
                     /translation="MLNRLKENYFFAIIRGKTVEDAIAIAKHAILGGIRNIEITYSTP
                     NASEVIRILSAEFEHDDAVIIGAGTVMTPDLAREAIAAGASFLVSPHFSREIAEVANQ
                     ASNLYFPGCATATEIVTAMNASCPIIKVFPGGVVGPGFIKDIHGPIPEVDLMPSGGVS
                     IDNVKEWKNAGAVAVGIGSALASRVEAEGYDSVTRIAASFVSALD"
     gene            complement(7890..8561)
                     /locus_tag="TVB59_000765"
     CDS             complement(7890..8561)
                     /locus_tag="TVB59_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000113633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HEL1009691.1"
                     /translation="MARPLVEKTAERLLKLILERGYEVGAKLPNEYELAQDLEVGRST
                     IREAVRSLATRNVLEVRQGSGTYISSKKGVSEDPLGFSLVKDTAKLTADLFELRLLLE
                     PRIAALTAQHATPKEVEALEKLVVDIEEAVAAGDPKHLQLDVNFHSLMAKYSGNIAMD
                     SLLPVINQSIHLINANYTNRQMKEDSLQAHRDILNAIKAGDPIAAHDAMLLHIMTVKR
                     TAFLS"
     gene            complement(8603..10393)
                     /gene="uidA"
                     /locus_tag="TVB59_000766"
     CDS             complement(8603..10393)
                     /gene="uidA"
                     /locus_tag="TVB59_000766"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HEL1009692.1"
                     /translation="MLYPILTKTRKIYDLGGLWQFKLGDHNPQELLASDELMVVPTSF
                     NDVVVDKDKRNYIGDFWYERFVDVPDLAADEELVLRFGSVTHNATVYVNGQALGQHKG
                     GFTPFEVLVPETHYQDNQIKVSVCANNILDYTSLPVGNYSEETQEDGSIKKIVKENFD
                     FFNYAGIHRPVKLMVRPKCHISDITITSDLSEDMTSALVEVSVETSAAVDEVKVTIFD
                     EEHKLVAQAIDGKARLDKVRLWEVLDAYLYTAHVEIIVDGNVVDSYDEPFGIRSIAVE
                     KGQFLLNGKPVYFKGFGKHEDTFINGRGLNEAANLMDMNLLKELGANSFRTSHYPYSE
                     EMMRLADRMGILVIDEVPAVGLFQNFTASLDLSPKDNGTWSVMKTKEAHEQAIRELVK
                     RDKNHPSVVMWVVANEPASHEEGAHEYFEPLIALYKALDPQQRPVTLVNLLLATPDRD
                     KVMDLVDVISLNRYYAWYVDHGDLIKGEVGLRQELLEWQKKFPNKPILMTEYGADTLP
                     GLHSMWDIPYTEEFQCRFYEMSHRVFDEIPNLVGEQVWNFADFETNLMIFRIQGNHKG
                     LFSRNRQPKHVVGLFKERWNTIPHYNYKKK"
     gene            complement(10414..11442)
                     /locus_tag="TVB59_000767"
     CDS             complement(10414..11442)
                     /locus_tag="TVB59_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEL1009693.1"
                     /translation="MKKVVSLGEILLRLSPPQYQTLKQATSLDCQFGGSELNVISSLA
                     QLGHQVSLISAIPDNDLGQMTKTFLFSRQINQEHIIEKGQRLGLYYYQKGFSLRASRV
                     TYDRCHSAFWESKRADYDLEHVFDEADWFHVSGITPALTSDLYELTYYLMTKARAEGL
                     TISFDLNFRASLWSSFQEARDLLSPLVQLADVCIGIEPLTLKGSGALDLKDQLGLNRP
                     YDDEALLKEVLARLADTYGVKCFAFTQREMDYTNEYLLKAYLYQNGSLYKTQKSGIQV
                     LDRVGTGDAFTAGLIHGLLSYKDEQATLDVAMASFKFKHTIEGDSNIMTQDDIDHLLA
                     KESHEIQR"
     gene            complement(11526..13070)
                     /locus_tag="TVB59_000768"
     CDS             complement(11526..13070)
                     /locus_tag="TVB59_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000416102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1009694.1"
                     /translation="MEKTIDQRVEEVTYNRAKVWQLVLFALNNASTNIYLFTFMFVTY
                     FSTGVLGLAAIFVSQIMGYIRIFDGFIDPAIGILIDKTETKFGKYRPILIIGNIITAL
                     SLILLLGLSGVSENIRFPLFILVLIIHKIGYSMQQTITKAGQTALTNDPKQRPIFNIV
                     DAIMTTLLMTGGQFVVSSFLVPKFGNFTPAFFHVLIYGTIVISAILGLLAVLGIWSKD
                     RKEFFGLGENTQKTALKDYLKVIKGNQPLQVLSIAAALVKFAVQFFGDSVVMVILFGV
                     LFGNYALSGQFSLLFIVPGILINIAFSGIARKRGLRFSYIRALQIGLVGLLAFGIVLF
                     MGNKGDLSLSHINLYTILFTVTLIIARYASQAPASLVLTMGADISDYETSESGRYVSG
                     MIGTIFSLTDSIASSFAPMVIGAVLAGIGFSKTYPTIETPLTPSLKMALIALHVGIPF
                     VALLVALILMSFYKLDKEEMVRIQEKIQVMKASSDKERVQAIAKNVPLSDMDYVDVTK
                     YPVDKD"
     gene            complement(13485..14744)
                     /locus_tag="TVB59_000769"
     CDS             complement(13485..14744)
                     /locus_tag="TVB59_000769"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEL1009695.1"
                     /translation="MRKIIINGGKALSGEVAVSGAKNSVVALIPAIILADDVVTLDGV
                     PAISDVDSLIEIMKLMGAMVTYQGDTLEIDPRGVQDIPMPYGKINSLRASYYFYGSLL
                     GRFGQAVVGLPGGCDLGPRPIDLHLKAFEAMGAQISYEGASMHLMTEAQQLHGAHIYM
                     DTISVGATINTMIAATKAKGKTIIENAAREPEIIDVATLLNNMGAHIRGAGTDVITIE
                     GVERLHGTRHQVIPDRIEAGTYIALAAAVGSGVRITNVLYEHLESFIAKLEEMGVRMT
                     VEEDSIFVEKQEALKAVTIKTSPYPGFATDLQQPLTPLLLRTEGRGSIIDTIYEKRVN
                     HVPELARMGADIAILGSQIVYHGSNRLSGAQVKATDLRAGAALVIAGLMAQGKTEISN
                     IEFILRGYANIIDKLTALGADIQLIED"
     gene            complement(15060..16265)
                     /locus_tag="TVB59_000770"
     CDS             complement(15060..16265)
                     /locus_tag="TVB59_000770"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEL1009696.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TCVYTGSVHVFGEISTTAYVDINRVVRDTIAEIGYTEAEYGFSAESVGVHPSLVEQSP
                     DIAQGVNEALEAREGQSDDFNAIGAGDQGLMFGFAIDETPELMPLPISLSHQLVRRLA
                     TLRKSGEISYLRPDAKSQVTVEYDEHDKPVRVDTVVISTQHDPEVSNDQIRQDMIEQV
                     IKAVIPAHYLDEKTRFLINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYARHGGGAFSG
                     KDATKVDRSASYAARYIAKNLVAAGLASKAEVQLAYAIGVAQPVSVRVDTFGTSTVSE
                     SILEAAVRQVFDLRPAGIIKMLDLKRPIYRQTAAYGHMGRTDIDLPWEQLDKVSPLTE
                     AVAALSEGA"
     gene            complement(16598..18817)
                     /locus_tag="TVB59_000771"
     CDS             complement(16598..18817)
                     /locus_tag="TVB59_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEL1009697.1"
                     /translation="MKSKKLMLMASLFMACHLTLTACQSTKQPTNQPKTKQTAKKATK
                     KKQSKKVKQTRKDRKGVAGIDFPTDDGFILTKDSKILSRTENGIVVEHNGHSHFIFYA
                     DLKGSKFEYLIPKDADLNKPEQTKAASGHHHTSANDPHHHYVFNPADIVAEDALGYIV
                     RHGDHYHYILKSSLGGQVAYPVPNHVPLSAPSSPSGKFAGVDYPTSDGFLFDGTGIVG
                     RTSYGLIVDHNGHNHLVTYESLRNSKWKHLIEQPKEEAPAKPQSDLEKTIALKKAYLA
                     KSLNIPEDSIRVEHTEEGIILDYPHGDHRHATYIDDIDLSKPFDPHAVDPHAKDRIGM
                     ATLRKLGFDEEVISSIIHANAPTEFPSRERDLEKMKAWLATVEYLNIGEIKDPLKRAG
                     LNLMPNIQILGIGFTPITDITPVYQFKNLKQLWMTQTGIKNYDFLKNLPTLEGIDISQ
                     NGVSDLSFLKAFPHYKVISAAGNDITDISILKELPNLESVNLDFNKITDLSALANAQK
                     LVAVSLEHNQIKDLSALSNKGQLTKLFVSNNPDLDLSTLKSSALKEITAKEVNLQSLS
                     FVKDLPALEQLVVDQNKLNSLTGLEHNKSLIQLSANQNMINSLALPGTQSSLQSLNLE
                     ENQLTNFEGVNNYLALEAINVNRNKINTLALKEPNQTLKYIQADGNHFPAEELAAESG
                     QFPQGIIKNFKAAEGGSLNNATPAEAVEDEHKPADTDQEAADKHDHEHHDHDEHHHG"
     gene            19344..20285
                     /locus_tag="TVB59_000772"
     CDS             19344..20285
                     /locus_tag="TVB59_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEL1009698.1"
                     /translation="MKTSEKIYQLLACSDDYVSGEYLAEQLKLSRTSVWKSIKSLESQ
                     GLHIESLKHKGYRLIQGDILLPELISQELNMPLSYHEKSQSTQLDAKQGIELKHTAPR
                     LYLAPSQYAAKGRLNRQFFASPHGGIYMSLHLKPNVPYADMPPYTMMVASSIVKAISR
                     LTGIDTQIKWVNDIYLGHKKIAGILTEAITSVETGVITDVIIGVGLNFFVTEFSENLK
                     ERAGSLFSNKPSITRNALIIDIWKLFTTIPIKDHIKVYKEKSLVLQKQVSFQENDRQK
                     TATAIDLTDEGHLIVQLDNGQLQVLRSGEISLSSWGD"
     gene            complement(20260..20463)
                     /locus_tag="TVB59_000773"
     CDS             complement(20260..20463)
                     /locus_tag="TVB59_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 family protein"
                     /protein_id="HEL1009699.1"
                     /translation="MTIRQFMFMAFICAFEAYFFSDLLFSGDYIFALFWGLLLFRDLR
                     RAYAIDQFTKNIINAVNPPRKKD"
     gene            complement(20844..22520)
                     /gene="dnaX"
                     /locus_tag="TVB59_000774"
     CDS             complement(20844..22520)
                     /gene="dnaX"
                     /locus_tag="TVB59_000774"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEL1009700.1"
                     /translation="MYQALYRKYRSQTFAEMVGQSVISTTLKQAVESEKISHAYLFSG
                     PRGTGKTSAAKIFAKAMNCPNQVKGEPCNHCDICRDITTGSLEDVIEIDAASNNGVDE
                     IRDIRDKSTYAPSRATYKVYIIDEVHMLSTGAFNALLKTLEEPSDNVVFILATTELHK
                     IPATILSRVQRFEFKAIKQPAICEHLAAILDKEGIAYEIEALHLIARRAEGGMRDALS
                     ILDQALSLSFDNRVTLAIAEEITGSISISALDDYVQHLIRQKTSQALANLETIYDSGK
                     SMSRFATDLLTYFRDLLIVKSGGDHHRQSALFDDNLAVSFDQLFTMIATVTKHLPEIK
                     KGTHPRIYAEMMTIQLAEQGQAADTAIPSSLLADVDDLKHEISQLRETISQLQAQKGL
                     TAQATPAHSIKPKAFTYKVDREKILKIMEETVQDSQQSRQYLEALKSAWNEILDSISA
                     QDRALLLGSEPVLANSENAILAFEAAFNAEQAMKRQDLNDMFGNIMSKAAGFSPHILA
                     VPKADFHHIRSEFAMTIKTKKETAKESEQATFDMPEGFDFLTDKIHLIED"
     gene            complement(22520..23017)
                     /locus_tag="TVB59_000775"
     CDS             complement(22520..23017)
                     /locus_tag="TVB59_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEL1009701.1"
                     /translation="MNKTTKIEHYQLLLAQAKALFSNESNALANLSNASALLKMTLPH
                     SVFAGFYLFDGQELILGPFQGKVSCVHIKLGKGVCGESAQSGQTIIVDDVKKHANYIS
                     CDSAAMSEIVVPMLKAGRLVGVLDLDSSLVADYDQIDQDYLEQFVALLLENTSFRFDM
                     FGVEN"
     gene            23197..23967
                     /locus_tag="TVB59_000776"
     CDS             23197..23967
                     /locus_tag="TVB59_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEL1009702.1"
                     /translation="MLLVFNGIEYECLNLVSPKQTFYQSAALILSTSLLGIYLIPFSL
                     AIAYLKRIYQIRISTLLLAGLGGLYISGFLASFGNQVLEQFWISLIKPNIALEEWTGA
                     LTGPFVEEPIKAFAAMLVIYLLPAINLKQKLVISLISGMGFQLTEDISYIASAADRSI
                     NDILPTTLARISSSPNSHWVYTGIFTMGAYLLIKKSQLFPRSLQIFWVVSPLALHFIW
                     NSPISDLAGVAVIHGTITTLIFISLFKKIHALDDSIAY"
     gene            complement(24149..24421)
                     /locus_tag="TVB59_000777"
     CDS             complement(24149..24421)
                     /locus_tag="TVB59_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002998338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEL1009703.1"
                     /translation="MLPSLILLFGWNAVVFAAYGSDKHRAQKGQWRLSEKMLLTLSLL
                     CGGIGAYLAGHYFNHKTKKWYFVLSWYMGILMTLVLCYYLYQWYIL"
     gene            complement(24444..25070)
                     /gene="udk"
                     /locus_tag="TVB59_000778"
     CDS             complement(24444..25070)
                     /gene="udk"
                     /locus_tag="TVB59_000778"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEL1009704.1"
                     /translation="MLKKPIIIGVTGGSGGGKTSVSRAILNSFPNARIAMIQHDSYYK
                     DQSHISFEERVKTNYDHPLAFDTDFMIQQLKELLAGRPVDIPIYDYKEHTRSNRTFRQ
                     EPQDVIIVEGILVLEDERLRELMDIKLFVDTDDDIRIIRRIQRDMVERGRSLESIIEQ
                     YTSVVKPMYHQFIEPSKRYADIVIPEGVSNVVAIDLINTKIASILGEL"
     gene            25166..26260
                     /locus_tag="TVB59_000779"
     CDS             25166..26260
                     /locus_tag="TVB59_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL1009705.1"
                     /translation="MITNLPTQWQEKLAKLGFTNLTPIQEQVFQPIVDGKSLLGISPT
                     GTGKTLAYLWPSLLRLSPKKAQQLLILAPNTELAGQLFEVTKEWAEPLGLTAQLFISG
                     SSQKRQIERLKKGPEIIIGTPGRIFELVRLKKIKMMAINTIILDEYDDLLSDSQYQFV
                     QKLSHYAPRDHQMIYMSATNKIEQVSLADHTLVIDLSKQALPCIEHCYMLVDKRHRTD
                     ILRKLANIPDFRGLVFFNSLSDLGATEERLQYSGASVASLASDVNVKQRKAILEAFKE
                     QSISLLLATDIVARGIDIDQLEYVINAEVPRNKEQYTHRAGRTGRMGRSGIVITLVSH
                     PEDIKRLKKFTKVTEMYLKHQQLYQKEIRG"
     gene            complement(26525..27811)
                     /locus_tag="TVB59_000780"
     CDS             complement(26525..27811)
                     /locus_tag="TVB59_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEL1009706.1"
                     /translation="MKKLNYILIILLSLLLVGVAFTFIRSWKIGQDTQRVIKLEQTAS
                     KDSPKIKKVKYLKKGKQDWYYLSPIEKADDFYVSNLPMSLYQGKQTDKAVIMVKPKLE
                     ASHIKQVNQLVIYKTVYKPQLFGLKKTTEKAVSRYHVKEDYSPFKLEELVAGRLDRIE
                     EEVGKLYPGKEIKLSTDTMIEKNQVLSDGFAIDSGNLILFGHMSIPLASLFDVINPDF
                     LEGSDKTAYEEYLEEKKAKEAEKEGQKLVALTFDDGPDPVTTPQVLDILAKYQAKGTF
                     FMMGSKVVGHEALVKKVSAAGHDVENHSWDHPDLTTLTVDQIQTQINTTNQAIEKACG
                     KRPVYLRPPYGATNDIVRRASGLKEMLWTVDTRDWENRNTAAIMANVKQQLQPGGVVL
                     MHDIHQTSVDALPSIMEYLKAEGYKCVTLSELYGSR"
     gene            28233..29396
                     /locus_tag="TVB59_000781"
     CDS             28233..29396
                     /locus_tag="TVB59_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL1009707.1"
                     /translation="MSQKLGKQLIRSVVTALAAIAFGIFPASETTNHITYAEVNSLTP
                     SVEWPLEQYPNYYSIEGKSNINTKDFPKLYTTTEKVYKKSGRSTKRVTVSDLQYAALD
                     GYGRSGAAYGIITKDMIAMSAGYREKWESNPEPSGWYTYHFKETGKLATEADYLHSKS
                     KIKRTSNNSYESIVLSNGKIRNGYLFDRSHLIADSLGGRPFRNNLITGTRTQNVGNND
                     RKGGMQYIENKVLNYINHNPQVHVYYKAVPIYSGSELLPRAVVVSALSSDGKIDETVR
                     VFNTVNGFTINYQYSGISHDKGMEASSESEAEDITDESTPVAEPADEEAMETEAAAND
                     TIVYVTSNGQSKVYWYNKDHLPEKVNLNKVVEMTEQEALNRGKHHSSLEKINQ"
     gene            complement(29519..32137)
                     /gene="alaS"
                     /locus_tag="TVB59_000782"
     CDS             complement(29519..32137)
                     /gene="alaS"
                     /locus_tag="TVB59_000782"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000811843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEL1009708.1"
                     /translation="MKQLTSAQIRQMWLDFWKSKGHSIEPSANLVPVNDPTLLWINSG
                     VATLKKYFDGSVIPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAIEWGFELLTSPEWFDFPKEKLYMTYYPDDKDSYNRWIALGVEPSHLIPLEENFWEI
                     GAGPSGPDTEIFFDRGEAYDPDHIGIRLLEEDIENDRYIEIWNIVLSQFNADPTIPRS
                     EYKELPNKNIDTGAGLERLVAVMQGAKTNFETDLFMPIIKEVEKLSGHTYDQDGDNMS
                     FKVIADHIRALSFAIGDGALPGNEGRGYVLRRLLRRAVMHGRRLGIHETFLYKLVATV
                     GHIMESYYPEILEKRDFIEKIIKREEETFARTIDAGSGHLDQLLAQLKEKGQDRLDGK
                     DIFKLYDTYGFPVELTEELAEDAGYKIDHEGFKAAMKEQQDRARAAAVKGGSMGMQNE
                     TLAGITEPSEFLYETETVASRLSVIIVDNERSEMVSEGQALLVFDQTPFYAEMGGQVA
                     DHGVIKNDKGDLVARVIDVQKAPNGQPLHTVEVLASLALDTVYTLAIDHKRRYAVEKN
                     HTATHLLHAALHKVIGEHATQAGSLNEEAFLRFDFTHFEAVTAQELRRIEEEVNEQIW
                     KALAITTTETDIETAKAMGAMALFGEKYGKTVRVVQIGDYSVELCGGTHLSNSSEIGL
                     FKIIKEEGIGSGTRRIIAVTGQQAFESFRKQEDILKEIAHTLKVPQIEQLPSKVVSLS
                     EQLRDLQKEMAELKEKAAAAQAGDVFKKVQEANGLRYIASEVSVSDAGVLRTFADNWK
                     QRDYSDVLVLAASIGEKVNVLVASKDKRAHAGNLIKALAPIVSGRGGGKPDMAMAGGS
                     DASKLSELLAAVPEHL"
     gene            complement(32493..33494)
                     /gene="prsA"
                     /locus_tag="TVB59_000783"
     CDS             complement(32493..33494)
                     /gene="prsA"
                     /locus_tag="TVB59_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEL1009709.1"
                     /translation="MKKSTKLLAGIVTLASAMTLAACQSTNDNTSVITMKGDTISVSD
                     FYNETKNTEISQRAMLNLVVSRVFEDQYGKKVSKKRTEEAYNKSAEQYGASFSAALAQ
                     SGLTTDTYKRQIRSAMLVEYAVKEAAKKELTDADYKKAYESYTPEMTTQVTTLDNEET
                     AKAVLGEVKAEGADFAAIAKEKTTAADKKVDYKFDSGDTKLPADVIKAASGLKEGDIS
                     EVVSVLDPATYQNKFYIVKVTKKAEKASDWKKYKKRLKEIVLAEKTQNIDFQNKVIAK
                     ALDKANVKIKDQAFANILAQYANTDKKASKANTSKSDQKSSSDSSKDSQSSKSKSEK"
     gene            complement(33557..34264)
                     /locus_tag="TVB59_000784"
     CDS             complement(33557..34264)
                     /locus_tag="TVB59_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEL1009710.1"
                     /translation="MVKSYSKNANHNMRRSIVKEDIVHYMRTQLKQNEGFLAELEAFA
                     RQENIPIIQHEVVAYFRLLLQSLQPKRILEIGTAIGFSALLMAENAPEAEIITIDRNA
                     EMIGFAKENFAKYDSRKQITLLEGDAADLLAGLTGEFDFVFMDSAKSKYIQFLPEVLK
                     HLKIGGMVVLDDVFQGGDIAKPIKEVRRGQRTIYRGLQDLFAATLDNPGLTASLLPLS
                     DGLLMIRKNQADIRLLD"
     gene            complement(34347..34985)
                     /locus_tag="TVB59_000785"
     CDS             complement(34347..34985)
                     /locus_tag="TVB59_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEL1009711.1"
                     /translation="MKTSLIFDMDGVIVDSEYIFLSTKTQMLLDRGIDTNEAYQYQFM
                     GTTFDDMWTTMKKECQLEDSVEALIAEMNHRRQAMLERDGVKAIAGAAQLIKHLHAKG
                     YRLAVASSSPKADIIRNLTALGLLDCFEVLVSGEEVARSKPAPDIFLKAAEWLSVDPK
                     TCLVIEDSKHGSQAAKAAQMTCIGFANPDYPLQDLSACDSIVKQLKAVCELL"
     gene            complement(35035..35667)
                     /locus_tag="TVB59_000786"
     CDS             complement(35035..35667)
                     /locus_tag="TVB59_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HEL1009712.1"
                     /translation="MTVNLIWDFDGTLVQSSEAIRQALGLLYQTYQLPFDEAWVMDTI
                     IQESIGQLLKRLAEAHQLDFSELLAFFTREQEARDHLIALMPTAKETLALTSQQGVKP
                     FIVTHKGRTTQAVLQRLGIADYFTEVITADCGFKRKPDPEALLFLIHHYQMDKSQTYY
                     IGDRPLDLAAARAAGISSINLLLPDSDDNHHISQLSDIVELFSGKNSSSN"
     gene            complement(35657..36214)
                     /locus_tag="TVB59_000787"
     CDS             complement(35657..36214)
                     /locus_tag="TVB59_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1009713.1"
                     /translation="MKEIRTIALADQAAFKRFQDILLAEKASGNTFVETKKVEDFAAF
                     VEQSRRFEVQTDHPDWSTSTNYYYFLDGQLVARIGCRWQLEKGDLATIGGHIGYVTRT
                     DYRGRGIMTDLLAFALQQYQERGIKRVLITANKDNIASRKTIEKAGGILEDIVQVADD
                     YPTTSLAGQAIARYWIDLRGKDCDS"
     gene            complement(36413..38215)
                     /gene="pepF"
                     /locus_tag="TVB59_000788"
     CDS             complement(36413..38215)
                     /gene="pepF"
                     /locus_tag="TVB59_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEL1009714.1"
                     /translation="MTDNRSHLEEKYTWDLSTIFATDAAWETEADSLLAAIEAARQQA
                     GHLLDSSSSLLDITELHLELARRVEKVYVYASMKNDQDTTVAKYQEYQAKASGIYAKF
                     SEAFSFYEPEFMALSQEAYQAFLAETPELTVYDHFFDKLFKTREHVLSQAEEELLAGA
                     QEIFNGAEETFSILDNADIAFPIVTNDKGEEVELTHGNFISLMESKDRKVRRAAYEAM
                     YSTYEQFQHTYAKTLQTNVKVQNYKARVHKYASARQAAMSANFIPEAVYDTLLENVNK
                     HLPLLHRYLKLRQEVLGLDDLKMYDVYTPLSETDLAIGYDEALEKAEKVLAVFGQDYS
                     ERVHRAFTERWIDVHVNKGKRSGAYSGGSYDTNAFMLLNWQDTLDNLYTLVHETGHSL
                     HSTFTRETQPYVYGDYSIFLAEIASTTNENIMTEALLHEVQDDKERFAILNHYLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSEYLNNLYADLNEKYYGLKKEDNHFIQYEWA
                     RIPHFYYNYYVYQYATGFAAASYLADKIVHGTQEDIDHYLTYLKSGNSDYPLEVIAKA
                     GVDMAKGDYLEAAFRVFEERLTELEDLVARGAHL"
     gene            complement(38205..>38646)
                     /locus_tag="TVB59_000789"
     CDS             complement(38205..>38646)
                     /locus_tag="TVB59_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEL1009715.1"
                     /translation="IHEDLFGKVSYLVKTCSLDDDLLAFLRLPYQRKGLSAYQLQMDK
                     HLLRRIQKALLAKDSKWLKKQEEAYLAGDNLLDRPLEAYYPQVKPIACSAGFCQIHED
                     LSHYYDCFEKYYAKAANKEVQKLFSPAYYVKMISNRNLGGPYDR"
BASE COUNT        11281 a         9117 c         7304 g        10944 t
ORIGIN      
        1 ttttaatcaa ccattttatt taatttttct gttaattttt gtataattaa ttttattaag
       61 ctgttttttg atgactatta attgttaatg ctgacaaaat aagctattat tattgatttt
      121 gttataaatc attaatatat tatatttttt cataatttaa aattattctt aatatatcat
      181 ctctaaaaaa cattatctgt tcaattgttt cacttatcaa caagcttata gcttgtctat
      241 catctgaagc aaggttgagc attaggcaca aaaagaaaag ctagaatgac cctctagctt
      301 ttctttagga ttaacaggct ctatcatctc catatcggat aaaactcccc accacaggga
      361 ttatggggct atttctgcag ctacaagggg ctgattaaca ggttttatcc tgaaatcttt
      421 ttaaatcatt cagagcaatc accgcagaac acgtaaagcc tctacttatc ctgtagcaac
      481 ctcagaagct atgccatagc tgggtatcaa tcaagccaca aaaggcatca acaggagaca
      541 ctccagtgaa ttcagattca ccagctaatt ttgcaaccaa agccttcata gtgttgtcct
      601 tgccatcgta ggcattaata taagtaccaa cctgtggcat atcagcaagg gcaaaggcat
      661 gctgaactga aacaacgatt gttgggacct catggacgta gaatggctga tccggtgttc
      721 ccttagcagc tggccagata atacgctgaa ctgtacctcc agaattgacg tccaccaaat
      781 taagaattaa atcataatgc tctgtaatgt ttgaaatcgg ctgcttttgt gcataaacat
      841 tagcaatagc cgctgcacgc tcttcctctg gtagctgcat gattcgctct tcggttgatt
      901 cccagacagt tacctcatgc ccacgcgcct ctagcaattc cttgacaatg tctgaggccc
      961 gtttcttctg tcctgcaatc atagcaccaa agccaccctt atagccctcc acgttaacaa
     1021 tcagcacacg cttgtagcgc tctggagtta ccgggaaaat ccctgcctgc ttgtttttca
     1081 caagggtaat ggccttgtcg gcaacctcat ctgcaattgc ttgagcctct ggtgtgttaa
     1141 tcaagaccat cgccttgtcc ttaggcagca taatatcttc tcggtgtcct tcaaagcgat
     1201 gaagtccaag ctttgctttc aagccaagcg tacgacgaag ggcgtcatga aggcgttcgt
     1261 cacttaaaat tcctgcctca tagccctctt tcatccattg taggtcttca tctgggtcat
     1321 taaagaataa aaagagatcg cagcctgcct caatcgctgt tggtaacaat aagcgacgtg
     1381 gcattgaggc tgtcatcgca accatatgcg aagcgtcagt cacaatagca ccattatagc
     1441 caagctcacc acgcagcagc tcatctaaga gggttttatt aagtgaggct ggaagcatat
     1501 catctagctc acgctcaggg tgcatggcct tttcaacatt tggcaggtga atatgtcctg
     1561 ccataatacc aggtaagcca gcctctgcaa gctcgccata aatacgtcca aagctagata
     1621 gccactcctc cttggtcatt gggtttgagg caaaggacaa atgatggtca cgctcatcaa
     1681 taccatcacc agggaagtgc ttggcaaagg gcatgatacc atattccata atccccttca
     1741 tatactcttt ggaaagctca atgatttgat caacatttac cccccagttg cgattagcaa
     1801 tgattggatt acgccaatta cgcgtcaaat caacaattgg cgcaaaggag gcattacagc
     1861 caacagctga cgcttccagt cctgcaatcc gtcccatttc ataagcgtat ttaggatcgt
     1921 ttgtcgcagc taccttgatt tcatcaccaa ccttagtgcc atcattgaca gcaccatcac
     1981 caccagcctc tgtattggca gcaatgagca ttggaatctt ggatttggtt tgtaaaatat
     2041 aattttgatc ccaaatttct gaagccatgc ctttattgta gcgaacagct gcaatatgat
     2101 aatcctcaag cacctgagtt aaataatcct ctgatcgact agcccccata ttaacaaata
     2161 gctgacctat cttctcctcc aaggtcattg ctgcaatggt atcctccacc cagcaaatag
     2221 cttcttcgtc taggctatat ggtttttttc ttaaatctac taaatgtgtc attgtacttc
     2281 ctttcaacta aagccttctc tgcttgcttt tctgttttaa tgaatggcgc tacagcaacc
     2341 tgctaccaag ccctaacagg ctcagctcca ctggtcagct acctgcctac ctatcaagat
     2401 tacgccagaa ggcttctgta aggctcttga catcaagctc tgtcaagtca ccagttgtaa
     2461 aagcttcagc agcatgtgac agatcctgcc acgagctagc ctccttacca acgaggattg
     2521 gaaaaaaagt gatctggttt tgctcagcag ctgctagatc acctggtgaa tctcctatca
     2581 tcatcatgcg ctctctcaca tatccttcat caatgagctg tgctatgaca gcctcttttt
     2641 tgccacgatc ctgacaatac aagccatcaa catgtgtcat caggccttga tcctgccatt
     2701 ccttttgaac ggcctcttta ttagctgagc tgacaacaaa aacctggcca agctggtgca
     2761 aggccttaag agcagctaaa gctcctagaa atgccaatgc ctctcctttg taggcctcaa
     2821 tctgacggtt tacctcattt gaccagtcca aggccttttg caggtcatca ctaggacgct
     2881 taagaagctc cgcctccaga gactgattgg ataatgaggc agtgtgttgt acccattgct
     2941 ttaaagcgtc aatccctgta actcctgcgt attctagccc cataacaagc ccaacaaagc
     3001 ggttaacacc gcgtgtacgc gaataaagat taatgcgatc ccactctttt aagaaagacg
     3061 cttggtctgc taccgcaaaa taatccgccg caagcggacc aaaaaagagc tgatgcttat
     3121 aagtcatggt gtccattgcg cagccatctg agtccacaca aaagacaaat tgttcagttt
     3181 tagctgtcat tccaacctcc aaatcatctg atgaattaat tctaacacag taagaaaacg
     3241 ctgtcaatca taaatcctaa tcaagcagcg tttcattttt aaaagctatc attacttgtt
     3301 gattgctaaa aaaggctaga gtgataagga acaatagaag ccacaaatca tcataccttt
     3361 attaatggca gcttggctac aaagcaagct gtcacgatag aaaaaccact tgaggcattg
     3421 cagtttgagt tctcaagtgg tttatttttt agcttagacg cctgaataag ctgcaaatcc
     3481 gccatcaatt ggcagaacaa cgccgttcac aaaggaagca gactgctcat cagccaagaa
     3541 aaagaggcct ccaattaatt cttctgcctc accaaagcgt cccattggtg tattcttaag
     3601 gattttttca gcacgagccg ttggctgtcc gtcctctgtg aaaaggaggc tacggttttg
     3661 attggttacc aaaaatccag gagcaatggc attacaacga atgccaacct tagaaaaatg
     3721 aacagccaac cactgggtaa agttggaaat ggctgcctta gccccagaat aggctgggat
     3781 ctttgttaat ggcgtaaagg cattcattga agaaatgtta ataatatttg cccccttacg
     3841 accaaccata tcctgagcaa agacttgcgt cggcaacaag gtgcctaaat agtttaaatt
     3901 aaagacaaag ctgatacctg cttcatcaag gtcaaagaag gtttttgtat cctctggcag
     3961 gcttgtgtcg tgaaactcat tatcggttgt tgccttaggg ctgtttccgc cagcgccatt
     4021 cactaaaata tctgctggac caaaatctgc taaaactgcc tgacgaacgg cctctaggtt
     4081 ttctttagac aatacatttg cctgataggc ctttgcaata ccaccctctg cctcaatatc
     4141 atcaacaaag gcctgtgccg cctcttggtt aaggtctaac agtgccacct tagcccctgc
     4201 ttttgcaaat gcctttgcca tactgccaca aaggacaccg ccagctcctg tgatcacaac
     4261 aaccttgtcc ttaaattcaa taactcgact catctcatgc ccctttttct atttatctcc
     4321 aactgttttt acagtaatgc caaaatctgg tatctttcca gctgcacgca tattagcctc
     4381 ataaagccca ttaaaatagg tcgcaccaag tgcccggtca tacagcccat agccaggggt
     4441 tttggtttga tctccccaga tacgacgacc atgatctgga cgaagtggtc cttgccagtc
     4501 ataatcaacc aataatttga taatagcatt catatcaatg tcaccagcct gtgacaagtg
     4561 agcggtttct tggaagcccc aatcaccagc agtgacatta cgcgtatgca taaagttaat
     4621 acgctggcgc ttaagcgcgt actccgtcat agcgatcaca tcattttgag gatcagaagc
     4681 ataggagccc acacacatgg taatcccatt attaggggaa tcataaaggt ctaagaagcg
     4741 ctctacagcc ttttgacctg ttatgatacg tggtaagcca aaaataccat aaggaggatc
     4801 atcagggtgg atagccatct taacgccagc tgcctctgct gttggcataa tagccttaat
     4861 aaaataatct aaattagccc acaggtcttc ttcggaaata tgatgacgat aatgctcaat
     4921 aatagccttc atctcttctt ttgagtaaga aaaatcccaa cccggtaggt tcaaatcatc
     4981 tgccacagga tccacatctg ccaagtctgc ctttaaaaaa gcaagtgagg ttgatccatc
     5041 aggcaatggg taattaagat ctgagcgagt ccaatcaaac actggcataa aattatagca
     5101 aaccacagga atacctgcct taccaacatt gatgatagag gtcttataat tttcaatcag
     5161 ctcatcacga ttgggctttc cttgcttgat gtcctcgtga acaggaattg attcgatgac
     5221 tgaaatctca aggcctgcag cctcaactat cctcttcaat tcaaggatat tttctagtgg
     5281 ccaagcctga ccaactggta catcatacac agctgttaca attccctgca taccaggaat
     5341 ggccttgatt tcctctaaac ttactggatc atgctttcca taccagcgaa acgacatttt
     5401 catagtatca tacctcgagt tctcgtaaac tccttttcct ttcgattcac acaattgtta
     5461 tttattattg tttttggggc taataccctt gcaactaaag ggcctgggcc tgctacttgg
     5521 tctagccttt gtaatctagt caatcaacaa gacgccgaca gcagctagca ggccgatatt
     5581 gtcctagcct cttttaagac taggacctta atcatagagc aacatcatat ttctatgctt
     5641 cttctagtta acgaccaagg cagcctagtt aaaatactgg atagcattat tgtaggcaat
     5701 gtcctgagcc attttaccaa gtgcctgata atcctctggt acctcacctt cttcaatcca
     5761 ctcaccaagg taggtcgaca aaatacgtct gaaataatca tgacgctgat aggataaaaa
     5821 tgaacgtgaa tccgttagca tgccgacaaa attagctaac aaaccttgct cagccaaggc
     5881 attcatctgg ctaatcatac caagcttggt atcagcaaac caccagcctg caccgaattg
     5941 cagatagccc gcaataccgt tttcattggc ttggaaatta gctagtgtat tagcaaccgc
     6001 gatattatag ctcggattta ggttatacca aatcatcttt ggcaggctgt ctctttgcac
     6061 cagatgatcc agcaggcgat tcatattgat tgctagtcct gtttggtctc ccagtgagtc
     6121 aacacccaca tctgccccca gcttgttgaa tatagctgaa tgattattgc gaagagcacc
     6181 aaaatgcacc tgagtaacaa agccatagtg cttataaagc ctgcaaagct ctgcaaacac
     6241 cgctgtctgc cattgcttga cctctaacgg ctgcggctga tagccctcta aaacccttgt
     6301 catgagacgg tctaattgct ctggctctgc tgcttcaaag acaatctctg taaagctgat
     6361 gtcactggcc ttacaaccat tttctgcaaa ataggcaata cgctcttcca tagccgctat
     6421 aaagctctta aaatctgtaa tagttcttcc ggtagcttga gcaagacgag ccacaaaatc
     6481 tgcaaagcgc tgatgctcaa taaaagcctc atctggtcta aaggttggcg cgacaaccgt
     6541 ctcaaaggta tcatcagcag ctaacctctt atgccaagct aggtcatcaa gcgggtgatc
     6601 tgtcgtacca ataaaccgca ctcggctatc tgcaatcaac tttctaggac taatctggtg
     6661 ctcaaccaag taagcattga tacgatgata gatttcctct gcattatcct cagtcagtag
     6721 ctcacagaca ccaaagacat ttttcaactc catcactgac cagtggtaaa caggattgcc
     6781 ataggagcgc tgaagtgtac gggcaaaggc cttgaattta tccagcttag aggctgagcc
     6841 tgtgatttct tcttccgaaa tgccattagc gcgcatcaag cgccacttgt aatgatcacc
     6901 accaagccaa aggtcaacaa tattgtcata aaccttgtcc tcaaaaattt cctttggatc
     6961 taagtgacaa tggtaatcaa aaataggctg atccttgatt tgttgataga ggcgctttgc
     7021 tgcctcattt tttagcataa aattgtcgtc attaaaagcc atctcgtcct cctcttatga
     7081 ccaattccct taatcaaggg ctgatacaaa tgacgctgca atacgggtta cactatcata
     7141 gccctcagcc tcaactcggc tagctaaggc tgaaccaatc ccaacagcaa cagcacctgc
     7201 atttttccac tccttgacat tgtcaatcga cacaccacct gatggcatca aatcaacctc
     7261 aggaatagga ccatgaatat ccttaataaa gcctggtcct acaacacctc caggaaagac
     7321 cttaataatc ggacaagagg cattcattgc tgtgacaatt tcagtagctg ttgcacagcc
     7381 tgggaaataa agatttgatg cctgattggc aacctctgct atttctctag aaaaatgagg
     7441 actaactaaa aagctagcac ctgctgcaat agcttctctt gccagatcag gcgtcatcac
     7501 tgtcccagct ccaataatca cagcatcatc atgctcaaac tcagctgaca atattctaat
     7561 aacctctgaa gcatttggag tagaataggt aatctcgata ttacgaatac cgcctaaaat
     7621 agcatgctta gcaatggcaa tagcgtcttc tactgttttt ccacgaataa tagcaaaaaa
     7681 ataattctct tttaatcggt ttagcatagg ctcctccttt tcatgaaacc gttgtcttag
     7741 ttttattata taaatcatca gatgatttgt caaggaaaaa gcaaaaaaag gacttggttc
     7801 tagtatctct aaaaccaagc cctcttattc gagccaagaa gcaaatcact caaaactcaa
     7861 tagactgttt ccggcaagca agcttaagct tatgatagaa aagccgttcg cttaactgtc
     7921 atgatgtgca ggagcatagc gtcatgtgcc gcgatcggat ctcccgcttt aatcgcattc
     7981 agaatatctc tgtgggcttg tagagaatct tctttcatct gacgatttgt gtaattggca
     8041 ttgatcagat gaatcgactg attgatcacc ggtagcaagc tatccatagc aatattgcca
     8101 ctgtattttg ccatcaagga atggaaattc acatccagct gcaaatgctt aggatcacca
     8161 gcagctacgg cctcttcaat atcaacaaca agcttctcta aggcttcaac ctcctttggc
     8221 gttgcatgct gtgctgtcaa agcggcaatc ctaggctcaa gcaatagccg caattcaaac
     8281 aaatcagcgg tcagcttggc tgtgtccttg actaaggaaa agcctaaagg atcctcagaa
     8341 acaccttttt tcgagctaat ataagtacct gatccttgtc taacctctaa aacatttcta
     8401 gttgctaagc ttctaacagc ttctctaata gtgcttcttc caacctctaa gtcctgtgct
     8461 aactcatatt cattggggag ctttgctcca acctcatacc cacgttctaa aattagcttt
     8521 aacaagcgct ctgctgtttt ttcgactaaa ggcctagcca tacaatccct tcttcctact
     8581 tattgctagc tactattgta cactatttct ttttataatt gtagtgggga atggtattcc
     8641 agcgctcttt aaacaaacca acaacatgct taggctggcg atttctagaa aaaagcccct
     8701 tatgattgcc ttgaatacgg aagatcatca gattagtttc aaaatcagca aaattccata
     8761 cctgctctcc aactagatta ggaatctcat caaaaacgcg gtgactcatc tcatagaagc
     8821 ggcactgaaa ttcctctgta tatggaatat cccacatcga atgaagacca ggaagcgtat
     8881 ctgcaccgta ctctgtcatc aggataggct tgttaggaaa cttcttctgc cattctaata
     8941 gctcctgacg cagcccaacc tctcctttga tcaagtctcc atgatcaaca taccaagcat
     9001 aataacggtt taaggagatc acatcaacca gatccatcac cttatctcga tcaggtgttg
     9061 ctaatagcag attaaccaat gttactggac gctgctgcgg atctagtgcc ttataaagag
     9121 caatcagcgg ctcaaagtat tcgtgtgctc cctcttcatg gctggcaggc tcattggcca
     9181 cgacccacat gacaacagaa gggtgatttt tgtcacgctt gacgagctca cgaattgctt
     9241 gctcatgcgc ttccttagtt ttcatgacag accaagtgcc attgtccttt ggcgaaagat
     9301 ccaaggaggc tgtaaagttt tggaagagcc ctactgccgg aacctcatca ataaccaaga
     9361 ttcccatacg atctgccaga cgcatcatct cctcagagta agggtagtgt gaggtacgaa
     9421 atgaattggc accaagctcc ttgagcagat tcatatccat taaattagct gcttcattca
     9481 atccacgacc gttgataaag gtatcctcat gcttaccaaa gcccttgaaa taaacaggct
     9541 tgccatttag taaaaattgt cctttttcaa ctgcaatact tctgatacca aatggctcat
     9601 cataactatc tacaacattg ccatctacga tgatctcaac gtgggcagtg tatagataag
     9661 catctaaaac ttcccataaa cgaaccttat caagtcttgc cttgccatca atagcctgcg
     9721 caacgagctt gtgctcttca tcaaagatcg tcaccttaac ctcatcaaca gctgctgagg
     9781 tttcaacaga tacctcgact aaggctgatg tcatatcctc agacaagtca ctcgtgatcg
     9841 tgatatctga gatatggcat tttggccgca ccataagctt cactggacgg tgaataccag
     9901 catagttgaa gaagtcaaaa ttctccttga caattttttt gatactgcca tcctcttgag
     9961 tttcttcact ataattgccc actggaaggc tggtataatc taaaatatta ttggcacaaa
    10021 cagatacctt aatttgatta tcctgataat gggtctcagg caccaacacc tcaaatggag
    10081 tgaagcctcc cttgtgttgc cctaaagctt gcccattaac atagactgtt gcattgtgcg
    10141 tgacagagcc aaagcgaagt accagctcct catcagcagc aagatctggc acatcaacaa
    10201 agcgctcgta ccaaaaatca ccgatgtaat tgcgcttgtc cttatccaca accacatcat
    10261 taaaggaggt cggcacaacc atcagctcat cagaggctag gagctcctgc gggttatggt
    10321 ctcctagctt aaattgccag agccccccta aatcataaat ctttcttgtt tttgtcagta
    10381 ttgggtataa catacgattt ctcctttatc acattatcgt tgaatctcat gcgattcctt
    10441 ggccagtaaa tgatcaatgt catcttgtgt catgatatta ctatcaccct caatggtatg
    10501 cttaaactta aagctagcca ttgcaacatc taaagtagcc tgctcgtctt tataacttaa
    10561 taagccatga atcagccctg ccgtaaaagc atcgcccgtc cctactcggt ccagaacctg
    10621 aataccagat ttttgggttt tataaaggct gccattttga tacaggtagg cctttaacag
    10681 gtattcattg gtatagtcca tctctctctg ggtaaaggca aagcatttta ccccataggt
    10741 atcagctaac ctagccagca cctccttcaa caaggcttca tcatcatagg gtctattcaa
    10801 gcctaattga tcctttaaat caagcgcgcc gcttccctta agcgtcagcg gctcaatgcc
    10861 aatacaaaca tcagccagct gaacaagagg cgacaagaga tctctagcct cctgaaagga
    10921 ggaccataga ctagccctaa aattcaaatc aaaggaaata gtcaatccct ctgccctagc
    10981 ctttgtcatc aaataatagg tcagctcata aagatcactc gttagagcag gcgttatccc
    11041 agacacatga aaccaatcag cctcatcaaa aacatgctcc aaatcatagt cagcacgctt
    11101 tgactcccaa aaggctgaat gacagcggtc ataggtaacc cgacttgctc gcaaagaaaa
    11161 gcccttttga taataataaa gccctaaacg ctgacccttt tcgataatat gctcctgatt
    11221 aatttgacgc gaaaagagaa aggtttttgt catttgtccc agatcattgt ctggaatagc
    11281 tgaaataaga gagacctgat gccctagctg agcaaggctt gagatgacat taagctcaga
    11341 acctccaaat tgacaatcta ggcttgttgc ctgctttaac gtctggtatt gagggggtga
    11401 caatcgcaag aggatttcac ccaaggatac aacttttttc acaacattcc tccttatact
    11461 atcaagctac tctattattt tataaaaaag tcagccactc ctcaaagaaa tagctgaccc
    11521 agcacctaat ccttatcaac aggatatttt gtcacatcaa catagtccat gtctgacagt
    11581 ggtacatttt tagcgatagc ctgcacgcgt tccttatcag agcttgcttt catcacttga
    11641 atcttctctt gaatacgcac catttcctct ttgtcaagct tgtagaatga catcaaaatc
    11701 aaagccacta gtaaggctac aaatggaata ccgacatgca gcgcaatcaa ggccatcttt
    11761 agacttgggg taagcggtgt ctcaatcgtt gggtaagtct ttgaaaaacc aataccagcc
    11821 agcactgcac caataaccat tggcgcaaat gatgatgcaa tcgagtcagt caaggagaag
    11881 attgtaccaa tcattcctga gacataacgg cctgattctg atgtttcgta gtctgaaata
    11941 tcagctccca ttgttagcac caagctagca ggcgcttgtg aggcatagcg agcaataatc
    12001 agtgtcacag taaacaaaat agtgtaaagg ttaatatgac ttaggctgag atccccttta
    12061 ttacccataa agagcacaat accaaaggct aacaagccaa ccaagccaat ctgaagagct
    12121 ctgatatatg agaaacgcaa acctctctta cgagcaatac ctgaaaaagc aatattaatc
    12181 aaaatccccg gaacaataaa cagcaatgag aattgaccag acaaagcata gttaccaaat
    12241 aaaacaccaa acaagataac catgacaacc gaatcaccaa agaattgaac agcaaactta
    12301 accaaggctg cggcaattga taggacctgt agcggctggt tgcccttgat aaccttcaaa
    12361 tagtccttca gagctgtctt ttgcgtattt tcaccaagac caaagaattc ctttctgtcc
    12421 ttgctccaaa taccaagcac tgccaataga cccaaaatag ctgagataac aatcgtgcca
    12481 taaatcaaca cgtggaagaa ggctggtgtg aagttaccaa attttggaac caagaagctt
    12541 gacacaacaa actgtccacc agtcatcagc aaggttgtca taatggcatc aacaatgtta
    12601 aagattggac gctgcttcgg atcattagta agggctgtct gaccagcctt agtgatggtt
    12661 tgctgcatag agtagccgat cttatggata atcaaaacca gaataaaaag tggaaaacga
    12721 atgttctcac taactccact tagaccaagc agcagaataa gtgatagggc tgtgataata
    12781 tttccgatga ttaggatcgg acgatactta ccaaacttag tttctgtttt atcaatcaag
    12841 ataccaatcg caggatcaat aaagccatca aaaatacgaa tataacccat gatctggctg
    12901 acaaaaatag ctgccaagcc tagaacacct gttgaaaagt aggtcacaaa cataaatgtg
    12961 aataggtaga tattggttga agcattgttt aaagcaaata aaacaagctg ccaaacctta
    13021 gcgcggttat aggtaacctc ttcaaccctt tggtcaattg ttttctccat cagagaaatc
    13081 ccccttttat cattcgctta ttgtgtaagc gttttatttc tacatgctta tcttactatt
    13141 catctgatga tttgtcaaca caatttaaac ttttttcgcc taattttaaa aaataaagct
    13201 tatttaggat tttaatcatt aaattcatct gataatttct ggtgtcttta aaaataatca
    13261 tcagacaatt actcattgac atcaaaaaaa ctgagccctg tgcaatacag aactaaatcc
    13321 tttcactaat atgtcgtgtc caacttttgg gggtcagtac acaggataga cagggggttc
    13381 ttaaaaatca aaagccccta aaaccactct cataccaagc agtcttagga gctctaagca
    13441 ttcatgtcag gtgataatca ttaggctatg aaagccttca gttcttaatc ctcaataagc
    13501 tgaatatcag cccctaaggc tgttagctta tcaataatgt tagcatagcc acgtaaaata
    13561 aactcaatat tgctaatctc ggttttaccc tgagccatta gacctgcaat caccaaagca
    13621 gcaccagccc gcaaatcagt tgccttaacc tgtgccccac tgaggcgatt agagccatga
    13681 taaacaattt ggctgccaag aatggcaata tctgctccca tacgagcaag ctctggcaca
    13741 tggttgacac gcttttcata tatcgtatca atgatactac cacgaccctc agtccttaaa
    13801 agcagaggag tcaaaggctg ctgtaggtca gtggcaaagc ctggataggg agaggtttta
    13861 atagtgactg ctttcaaggc ttcctgcttt tccacaaaaa tagaatcctc ttcaaccgtc
    13921 attctcacac ccatttcctc tagcttagca ataaagctct ctaagtgctc gtaaaggaca
    13981 ttggtaatcc ttaccccact accaacagcg gctgccaagg caatataggt accagcctca
    14041 atgcgatctg ggatcacctg atgtctggtg ccatgaagcc tttcaactcc ctcaatcgta
    14101 atcacatcag tacctgcacc acgaatatgc gcccccatgt tatttaacag tgtcgcaacg
    14161 tcaataatct caggctctct agctgcattt tcaataatgg tcttaccctt tgcctttgtc
    14221 gcagcaatca tagtattaat ggtagcgcct acactgatag tatccatgta gatatgagcg
    14281 ccatgaagct gctgagcctc tgtcatcagg tgcatgcttg ctccctcata agatatctgg
    14341 gcccccattg cttcaaaagc cttcagatga agatcaatag gcctagggcc taagtcacag
    14401 ccacccggca agcccacaac cgcctgccca aagcgtccca atagactgcc ataaaaatag
    14461 taagaggctc ttaggctgtt aattttacca taaggcatag gaatatcttg aacccctctg
    14521 gggtcaatct ccaaggtatc cccctgatag gtcaccatag ctcccatgag cttcatgatt
    14581 tcaataagac tgtcaacatc actaatagct ggtaccccat ctaaagtgac aacatcgtct
    14641 gccaaaataa tcgcaggaat gagagctaca acgctatttt tagcgcctga aactgccacc
    14701 tctccggata aggcttttcc accattaata ataatttttc gcatactttc aaaactttct
    14761 gatactagaa ttcaaccttt ttattttatc acaaatagcg gtctattaca atcacctcat
    14821 caccagctgc tgcaacaggc ttaacaacct gcctcttgat cacttttcat aacaggtttt
    14881 tgagaagcca gactcttatc tggatctttc ttctgctgcg caggcctttt tgtctttcat
    14941 agccgccaag cctgacaagt tttgctggac taaaaaagct cccaaccagc agcacagccg
    15001 ctagctcagg agctattata cctttaagtc aatcatcaac taaccggcgc tcaatctgct
    15061 taagcaccct ctgacagtgc tgccaccgct tctgtcaatg gagatacctt gtccaattgt
    15121 tcccaaggca ggtcaatgtc tgttcgcccc atgtgcccat aggctgctgt ctgcctatag
    15181 attggacgct tgagatcaag catcttaatg atccctgctg ggcgcaggtc aaagacctga
    15241 cgaacagccg cttccaaaat actttctgac actgttgatg tcccaaaggt atccacacga
    15301 actgaaactg gctgtgcaac cccgatagca taggctaatt gaacctctgc tttacttgca
    15361 agccctgctg ccacaaggtt tttggcaata taacgagctg cataagaggc tgagcggtca
    15421 accttagttg cgtctttacc agagaaggca ccaccaccat gacgcgcata gccaccatag
    15481 gtgtcaacaa tgatcttacg accagtcaag ccagaatctc cctgaggacc accaataaca
    15541 aaacgcccag tcggattgat aaggaatctt gtcttctcat ctagataatg ggctggaata
    15601 acagccttaa tcacctgctc aatcatatct tgacgaatct ggtcattgct tacttctgga
    15661 tcatgctggg ttgatataac aactgtatca acacgaacag gcttatcatg ttcatcatat
    15721 tcgaccgtaa cctgtgattt agcgtctgga cgcaaatagc tgatctcacc tgattttcgc
    15781 agtgtcgcca aacggcgtac aagctggtga gataaggaaa tcggcagtgg cattagttct
    15841 ggtgtctcat caattgcaaa gccaaacatt agcccctgat ccccagcacc aatcgcattg
    15901 aaatcatcgc tttgtccttc acgtgcttca agtgcttcat taacgccttg agcaatatct
    15961 ggtgactgct caaccagaga tggatgaaca cccactgatt ctgctgaaaa gccatattct
    16021 gcctcagtat agccaatctc agcgatggta tcacgaacca cacgattaat atccacatag
    16081 gcagttgttg aaatttctcc aaaaacgtgg accgagcctg tgtaaacgca ggtctctgca
    16141 gcaacgtgtg cctctggatc cttggctaaa atagcatcta aaatagcatc tgaaatttgg
    16201 tctgcaatct tatctggatg cccttcagat actgattcag acgtgaaaag tttacgttct
    16261 gacataaaaa tgtcccccct taaaaagaat gatacccacc agcacacatg ccagatagga
    16321 ttttcctagc ctcactcatc aagccagccg ccaatacaaa aggactgtat ccaagctagc
    16381 ctatgactaa cgcttagcga gttacaaagt accggctttt agactgctat cctcagataa
    16441 caaagccgtc ttatcgggac ttaataactt atttattata ccacttttag cgggatttgt
    16501 aagagctcca tcagcttttt tctcaaaata agaaaaggaa taccgctaca ggcgtattcc
    16561 tcctcttaat gtcgtgataa tcagcgcaag ctatcgatta accatggtgg tgctcatcgt
    16621 gatcatgatg ctcatggtca tgcttatctg ctgcctcttg atcagtatca gccggcttat
    16681 gctcgtcttc aacagcttct gctggtgtgg cattatttag actaccaccc tctgctgcct
    16741 tgaagttctt gataattcct tgtgggaatt gtccgctttc agcagctagc tcctcagctg
    16801 ggaagtggtt accatcagcc tgaatgtatt tcagggtttg gttaggctcc ttcaaggcca
    16861 aggtgttaat cttgttacga ttaacattaa ttgcttctag ggcgagataa ttgttgacac
    16921 cctcaaaatt agtcagctgg ttctcttcaa ggttaagaga ctgtaatgag ctttgtgtac
    16981 ctggtaaggc caagctatta atcatgttct ggttagctga tagctgaatc aggctcttat
    17041 tgtgctcaag acctgtcaag ctgttaagct tgttttggtc aaccactagc tgctctaatg
    17101 ccggtagatc cttgacaaag ctaaggcttt gtaaattaac ctccttggca gtgatttcct
    17161 tgagagcaga ggattttaag gttgacaaat caaggtcagg gttgtttgac acaaagagtt
    17221 tggtcaattg tcccttgttt gacaaggcac tcaagtcctt aatctgattg tgctctaggc
    17281 tgacagcgac tagcttttga gcatttgcca aggcagaaag atctgtaatc ttgttaaagt
    17341 caaggttaac ggactctagg tttggcaatt ctttcaaaat agaaatatct gtgatatcat
    17401 ttcctgctgc cgaaattacc ttgtaatgcg gaaaggcttt aaggaagctc aaatcagaaa
    17461 caccattttg agaaatatca attccttcaa gcgttggcag gttcttcaag aaatcataat
    17521 ttttaatgcc ggtctgtgtc atccacaatt gtttgaggtt cttgaactgg tagactgggg
    17581 taatatcagt gattggggta aagccaatac ctaaaatctg tatattaggc atcaggttta
    17641 aacctgcccg cttaagagga tccttaatct caccgatatt gaggtattca acagtcgcca
    17701 accatgcctt cattttctct aggtctcgct ctcttgatgg aaactcagtt ggtgcatttg
    17761 catggataat ggacgaaatc acttcctcat caaagccaag ctttctcaga gttgccatac
    17821 cgattctatc cttagcatgc ggatctactg catgaggatc aaaaggtttt gataaatcaa
    17881 tatcgtcaat ataggttgca tgacgatggt caccatgtgg atagtcaaga atgatacctt
    17941 cttctgtatg ctccacacga atgctgtcct caggaatatt taatgactta gccaaatatg
    18001 cttttttcaa agcaatcgtt ttctcaagat cactttgtgg cttagctggt gcttcttcct
    18061 ttggctgttc gattaaatgc ttccacttgc tgttacgcaa gctttcataa gtgactaaat
    18121 gattgtggcc attgtgatca acaatcaatc catatgatgt tcgaccgaca atacctgtcc
    18181 cgtcaaacaa gaagccatca cttgttgggt aatcaacacc tgcaaatttt ccagacggtg
    18241 atgatggagc tgatagtggc acatggttag gcactggata agctacctga ccacctagtg
    18301 agctttttag gatatagtgg taatgatcac catgacggac aatatagccc aaggcgtcct
    18361 cagctacaat atcagctggg ttaaacacat agtgatggtg cgggtcatta gcactagtat
    18421 ggtgatgacc tgatgctgcc ttggtctgct caggcttgtt taggtcagcg tcctttggaa
    18481 tcaggtactc aaacttgctg cccttgagat ctgcataaaa aataaaatgc gaatgcccat
    18541 tatgctcaac aacaataccg ttttctgttc tagataagat ttttgaatcc ttggtcaaga
    18601 taaaaccgtc atcagttgga aagtcaatcc ccgctactcc cttacggtct tttcttgttt
    18661 gcttaacctt tttagactgt ttctttttgg tcgctttttt agctgtctgt tttgtcttag
    18721 gctgatttgt tggctgcttt gtcgactgac aagctgtcag ggtcaggtga caagccataa
    18781 acaggctagc cattagcatt aattttttac ttttcatctt tcctccataa attaactggt
    18841 taaataagat attaactagt taaatatacc aaaaaaacaa ataatttcaa ctgttttctt
    18901 atttttaatt cattctcatt caacaatcat agtagcttgg ctaggttggc agaaaaatga
    18961 gcctctccta ctctcatcaa ataaacagat agccttaatg atggctgaga taacagcata
    19021 caaagtcgtt aaagtcactt gtaagaaaaa gaaggacata tcttaccacc actatcttgc
    19081 tcatcaaagc cctacggctt tcagacaaaa tcttcataac agcggaaagg ctgatgaagc
    19141 agctcagaca aaaagagcaa gctccttaac gtcaaggatc agagatcagc acaaaaataa
    19201 cagcaggcta cattaagaac tgcaattcct tgaaatagaa ttgctttttt acaaaaaaat
    19261 cgtctcccta gactgttcca tcatctcacg tcatttgtat tatttgctct tgaaatccag
    19321 tcattttata ctatactaga attatgaaga catctgaaaa aatttaccaa ttactagctt
    19381 gcagcgacga ctatgtcagt ggagaatact tggcagagca gctcaagctt tctagaacct
    19441 ctgtctggaa atccatcaaa agccttgaaa gtcaaggcct tcacattgaa tccctcaagc
    19501 ataagggcta tcgccttatt caaggagata tattgctgcc agagctcatc agccaagagc
    19561 tcaacatgcc tttatcttat catgagaaaa gccagtcaac acagctagac gccaagcaag
    19621 gaatcgagct aaagcatact gctcctaggc tctatctcgc tccaagtcag tatgcggcca
    19681 aggggcggct taatcgccaa ttctttgcgt cacctcatgg cggcatttac atgtccttgc
    19741 atctcaagcc aaatgttcct tacgcagaca tgcctcctta caccatgatg gtggcctcta
    19801 gtattgttaa ggctatttca agattgaccg gtattgacac ccaaatcaaa tgggtcaatg
    19861 atatttacct tggccataaa aaaatcgccg gtatcctgac tgaggccatt acctctgtgg
    19921 aaacaggcgt cattactgat gtgattattg gcgtagggct taactttttt gtaaccgaat
    19981 tttctgaaaa cctcaaagaa cgagcaggct ctctttttag caacaagcct agtattactc
    20041 gaaatgccct aatcattgac atttggaagc tctttaccac aataccaatc aaggaccata
    20101 ttaaggtcta caaagaaaaa tcacttgtcc ttcaaaaaca agtgagcttc caagaaaatg
    20161 atcgtcaaaa aacagcaact gccattgacc tgactgatga aggacacctc atcgttcaat
    20221 tagacaatgg tcagctacag gtcttaagga gcggcgaaat tagtctttct tcctgggggg
    20281 attaacagca ttaatgatgt ttttggtaaa ttggtcaata gcataagcac gccttaaatc
    20341 tctaaagagc aaaagacccc aaaacagagc aaaaatataa tcgcctgaaa ataataaatc
    20401 gctgaaaaaa taagcttcaa aggcacaaat gaatgccata aacataaatt gtcgaatagt
    20461 catactacta ttataccaag aaaactaaat ttccactaac gattttcacg cagcttgaag
    20521 aaaaaggcag ttagcctgct tcaagctttt ttgctgctct ttgatagcct gtaacagtca
    20581 aataaaaaag agctcactct aaaaacgacg ccaaaagcca gcttgattgc taggcttgta
    20641 gtcaattgtc tcaaatcagt gaatcactaa gccttataag aactcagtca ttgggtcaca
    20701 atgacaccta gctctaagca gcaaaaaaga gaaccacacc ggtcctctct agcttggctt
    20761 gtcagctatc tattagtgct gacaatgagc cctgtcatct ccttattcta gacaattgat
    20821 acactaccaa tcatcagcta gcgctaatcc tctatgagat gaatcttatc agttaaaaag
    20881 tcaaacccct caggcatgtc aaaggtcgct tgctcagact ctttggctgt ctcttttttg
    20941 gttttgatgg tcatggcaaa ctccgagcga atatggtgga agtctgcctt tggtactgcc
    21001 aagatatgag gagaaaaccc tgctgcctta ctcatgatat tcccaaacat atcattcaaa
    21061 tcctgacgct tcatggcctg ctcagcgtta aaggcggcct caaaggccaa aatagcattt
    21121 tcactattgg ctaaaacagg ctccgagcct agtaacaaag ctcgatcctg tgcagaaata
    21181 ctatctaaaa tctcattcca agcacttttt agcgcttcta aatattgtcg tgactgctgg
    21241 ctatcttgaa cagtttcctc catgattttc aatatctttt cccgatcaac cttgtaggta
    21301 aaggcctttg gcttgatgga atgagctggt gtagcctgcg cagttagacc cttttgagcc
    21361 tgtagctgtg atatcgtctc cctcagctga ctaatctcat gcttcaagtc atcaacatca
    21421 gctagcaggc tagacggtat cgcagtgtct gctgcttgtc cttgctctgc cagctgaatg
    21481 gtcatcattt cagcgtagat tctaggatgg gttccttttt tgatctcagg caaatgcttg
    21541 gttactgtag caatcattgt aaaaagctga tcaaaagaca ctgcaaggtt atcatcaaaa
    21601 agagctgact gcctgtgatg atcaccacct gatttcacaa tgagcaggtc tctaaaatag
    21661 gttagcagat ccgttgcaaa gcgactcatg ctcttgccac tatcataaat tgtttctaga
    21721 ttagctaagg cctgacttgt tttttgcctg atgagatgct gaacgtagtc gtctaaggcc
    21781 gaaatagaaa tagagcctgt gatttcttct gcaatagcaa gcgtcactcg attgtcaaag
    21841 gataggctca aggcctgatc taaaatggat agggcatcac gcatgccacc ttctgctcgt
    21901 cttgcaatta aatgaagcgc ctctatttca taggctatgc cctccttgtc cagtatcgcc
    21961 gccaaatgct cacaaatagc tggctgctta atggctttaa attcaaatcg ctggactcta
    22021 gacaaaatag tagctggaat cttgtgtagt tctgttgtgg ctaggataaa aaccacattg
    22081 tcactcggct cttcaagggt ctttaggagc gcattgaagg cccctgttga tagcatatgc
    22141 acctcatcaa taatataaac cttgtaggtt gcccggctag gagcataggt tgacttatct
    22201 cgaatatcgc gaatttcatc aacaccatta ttagaggcag catcaatttc aatcacgtcc
    22261 tccaggctgc cagttgtaat atctcggcaa atatcacaat gattgcaggg ctctcccttg
    22321 acctgattag ggcagttcat tgccttagca aaaattttgg ctgcgctggt tttaccagtt
    22381 cctcttggac ctgaaaagag gtaagcatgg cttatctttt ctgactcaac agcctgcttt
    22441 aaggtggtcg aaataactga ctgcccaacc atttcagcaa aggtctggct acgatacttc
    22501 cggtaaaggg cttgatacat taattctcaa ctccaaacat gtcaaaacga aaagatgtat
    22561 tttctagtaa taaggctaca aattgctcta aatagtcttg atctatctga tcataatcag
    22621 caacaagact ggaatccaaa tccagaacac caacaagcct gccagcctta agcattggca
    22681 caacaatctc gctcatggct gctgaatcac aggaaatgta attagcatgc tttttgacat
    22741 catcaacgat gatggtttga ccagattgag ctgattctcc acatactccc ttgccaagct
    22801 tgatatgcac acaggaaacc tttccctgaa agggaccaag gatcaattct tgaccatcaa
    22861 aaaggtaaaa gcctgcaaaa acagaatgag gcagggtcat ttttaagagg gcactagcat
    22921 tagagagatt ggccaaggca ttgctttcat tagaaaataa ggctttagct tgagccaata
    22981 atagctgata atgttcaatt tttgtcgtct tattcatggt tcttattata acatatctgc
    23041 tactaatcgt taaacgattt ccacaggaaa agaattttaa tcagcctctc tagaaaagaa
    23101 agagatttta tgataaaata gtgagtaata ttaaaaaaat aggagagtca gatgccgttg
    23161 ttgagatata aaaagattat cgctacgacc ttatttatgt tattagtgtt taatggtatt
    23221 gagtatgaat gtctaaacct tgtcagtccc aaacaaacct tttaccaatc cgctgcctta
    23281 atcctctcaa ccagcctact agggatctat ctgattccct tttcactggc tattgcttat
    23341 ctcaagcgca tctaccagat aaggatctca accctgctat tagctgggct aggcggtctt
    23401 tatattagtg gctttttagc ctcctttggc aatcaggttt tagagcaatt ttggattagc
    23461 ctgataaagc ccaatattgc cttagaggag tggacgggag ctttgacagg gccttttgtg
    23521 gaagagccta ttaaggcctt tgcagctatg cttgtcattt atttgctgcc agctattaat
    23581 cttaagcaaa aattagtcat cagtctcatt tctggcatgg gattccagct gactgaggac
    23641 attagctata ttgcaagtgc ggctgatcgg tccataaatg acattttgcc tacaacgctt
    23701 gccaggatta gcagctcacc aaactctcat tgggtctata ctggtatttt tacaatggga
    23761 gcataccttt taattaaaaa atctcaatta ttcccaaggt ctctgcagat tttctgggtg
    23821 gtaagtcctc tagccctaca ttttatatgg aactctccta tctcagattt agctggtgtc
    23881 gcagttattc atggaacaat aacaaccctt atctttatca gtctattcaa aaaaatccat
    23941 gccctagacg acagcatcgc ctactagcgt cataggacac gagcaaccaa gcccagccgc
    24001 atttgggcat gtgatggctc atatgcatat atagctactc acctctcgct taagctatag
    24061 gcagctaaat acctatcaca atagcagaaa aaatgactac cagtcttaaa agggctagta
    24121 gtcattttaa gctaaaaaca agcacttctt acaggatata ccactgatac agataatagc
    24181 aaagcacaag ggtcatcagt atccccatat accatgaaag gacaaaatac catttcttcg
    24241 ttttatggtt aaaataatgc ccagctagat aggctccaat cccaccacat aagagtgaca
    24301 acgttaatag cattttctca gaaagtcgcc attgaccttt ttgggctctg tgtttatcac
    24361 tgccataggc cgcaaagacc acagcattcc aaccaaaaag caagattagg cttggtagca
    24421 tttgtctgtc tccaatcaca gcactacagc tcacctaaga tgctggcaat ctttgtgttg
    24481 atgagatcaa tagcaaccac attgctaacc ccttctggaa tgacaatatc agcatagcgc
    24541 ttacttggct caataaattg atgatacatc ggcttgacaa cgcttgtgta ctgctcaata
    24601 atgctctcaa ggcttctgcc acgctcaacc atatcacgct gaatacgacg gataatccga
    24661 atgtcatcat ctgtatcaac aaaaagcttg atatccatca gctcacgcaa acgctcgtcc
    24721 tctaatacca gaatcccctc aacaataatg acgtcctgag gctcttggcg aaaagttctg
    24781 ttgctgcgag tatgctcctt ataatcatag attggaatat caacaggccg gccagccaag
    24841 agttccttta gctgctgaat catgaaatcc gtatcaaagg ctaacgggtg atcataatta
    24901 gtcttaaccc tttcctcaaa gctgatatgt gattgatcct tgtaatacga atcatgctga
    24961 atcatcgcaa ttctcgcatt tggaaagcta tttaaaatgg cacgagacac gctagtctta
    25021 ccaccaccag aaccaccagt cacaccaata ataatgggtt ttttaagcat tgtaaactcc
    25081 aaatctaaaa gtctttcggt ctattttacc aaatttgcca ctataatgct ataatgaaga
    25141 gaaaacaaaa taaaaggata gatatatgat aaccaacctt cccactcaat ggcaggaaaa
    25201 gctggcaaag cttggcttta ctaatctcac cccaatccaa gagcaggtct ttcagcccat
    25261 tgttgatggc aaaagcctat taggcattag ccccaccgga acaggcaaaa ctctggccta
    25321 tttatggcca agccttctca ggctaagccc taaaaaagcc cagcagttgc tgattttagc
    25381 acctaatact gagctagctg gacagctttt tgaggttacc aaggaatggg cagagccctt
    25441 aggattaact gcgcagctct ttatttccgg aagcagccaa aaacgccaga tcgaacgcct
    25501 caaaaaaggc ccagaaatca ttatcggaac accgggacgc atttttgaat tagtaaggct
    25561 taaaaaaatc aaaatgatgg ccatcaatac catcatttta gatgaatacg acgacctact
    25621 gagtgactcc caataccagt ttgtccaaaa actctcccat tacgcgcctc gtgaccatca
    25681 aatgatctac atgagtgcta ctaacaagat agagcaagtc agtctagcgg atcatacctt
    25741 ggtcattgat ctgtctaagc aagcattgcc ttgcattgag cactgctaca tgctggttga
    25801 caaaaggcat cggaccgata tcctacgtaa gctagcaaat attcctgact ttcgtggtct
    25861 ggtctttttt aacagcctgt cagacctagg tgctactgaa gaacgcctgc aatatagtgg
    25921 agcttctgtt gcttctctag ccagtgatgt gaatgtcaag cagcgaaagg ccattttaga
    25981 agcctttaaa gagcagagca tttcactgct gcttgcgacg gacatagtcg ctcgtgggat
    26041 tgatattgac cagctagaat acgtcattaa cgctgaggtt ccccgtaata aagagcaata
    26101 tactcataga gctgggcgaa ccggtcgtat gggacgatca gggattgtca taactcttgt
    26161 cagtcaccct gaagacatca agcgccttaa aaaatttacc aaggtcactg agatgtactt
    26221 gaagcatcag caattatacc aaaaagaaat aagaggctag ctcaaaggat ataaacctaa
    26281 aaagcttgcc tccaagtatg atgtaaagca actaatcact atttcttacc cttgctacta
    26341 aaaaaacgaa cgtaaagtcc ttctgacatg aagtcaaaac cttacgttcg ttttatatta
    26401 tactgacacc actggcttta ttagtatagt agatactggc catgcttagc cagactagat
    26461 actttcttga agtgagcccg ccatttagtc atgctctaga gccttacttg ctttttctga
    26521 ctgactagcg gctaccatat agctcagata aggtcacaca tttgtatcct tccgctttta
    26581 ggtattccat aatacttggc aaggcatcta cactggtctg gtgaatatcg tgcattagaa
    26641 caacccctcc aggctgcaat tgctgcttga catttgccat gatagcagca gtattacgat
    26701 tttcccaatc tctggtatca actgtccaaa gcatttcctt aagacccgat gcccttctaa
    26761 caatatcatt agtagctcca taaggaggac gaagatagac tgggcgtttt ccacaggcct
    26821 tttcgatggc ttgattggtc gtattgatct gtgtttggat ctgatcaacg gttagggtcg
    26881 tcaaatcagg gtgatcccaa gaatgattct caacatcatg accagcagca ctaaccttct
    26941 taaccaaagc ctcatggcca acaaccttag accccatcat aaaaaaggtc cccttggcct
    27001 gatatttggc caaaatatct aaaacctgcg gtgtggtcac agggtctgga ccatcatcaa
    27061 aggtcagagc gactagcttt tgtccctctt tttctgcctc ttttgccttc ttttcctcca
    27121 aatactcttc ataagcagtc ttgtctgaac cctctagaaa atctggatta atcacatcaa
    27181 acaggcttgc aagaggtatt gacatatgac caaataaaat aagattaccc gaatcaatgg
    27241 caaagccatc gcttaatacc tgattttttt ctatcatcgt atcagtgctc agcttgatct
    27301 ctttgcctgg ataaagcttg ccaacctctt cctcgatgcg atctaagcga ccagcaacta
    27361 gctcctctag cttaaagggg ctataatcct ctttcacatg gtaacgacta acagcctttt
    27421 ctgtagtctt ttttagacca aataactgag gcttgtagac cgtcttgtag ataaccaatt
    27481 gattgacctg cttgatatgt gaagcctcaa gcttaggctt taccatgata acagccttgt
    27541 cagtctgctt gccttgatac agagacatag gcagatttga cacataaaaa tcgtcagcct
    27601 tctcaatcgg agacaggtaa taccaatcct gctttccttt cttgagatac ttgacctttt
    27661 tgatctttgg actatcctta gaagcagtct gttcgagctt aatgactctc tgagtatcct
    27721 gccctatttt ccaagatcta atgaaggtaa acgcaacacc gaccaacaat aaacttaata
    27781 aaataatgag aatataattt agctttttca atctcgtcct ccaattaccc tacaatttta
    27841 acacaagata gttggaaaat aaataaaaaa agttaggttt ccttaacttt tttcagtcca
    27901 aaataagggc aaaaaagtgt tttatggtgc aggatttgcc tgagttattt tccctttatc
    27961 acagccattt gtcactggat aaggggctag atattatacc taaagcttct ctttattgct
    28021 atcattattc tgacattctt aggcatgcta tttcccttga taggacttga ttgctgtttc
    28081 tttagcttgt aaggatctcc taaaaatgag agtattttta agcctataat ttatatattc
    28141 gaaaaatttt gacaaaaatg aggaaaaata ttgatttatt tagctttagt gataaaatga
    28201 gggtgaaaaa ttaaataaag gaggacattg atatgtctca gaagttggga aaacaactta
    28261 ttcgctctgt tgttactgcc ttagccgcca tagcatttgg aatatttcct gcaagcgaga
    28321 cgactaatca tatcacctat gcagaggtta actccttaac cccttcggta gaatggcctt
    28381 tagagcagta tcctaattac tatagcatag aaggaaagtc taatatcaac accaaggatt
    28441 ttcctaagct atacaccact accgaaaagg tttacaaaaa aagtggtcga agcactaagc
    28501 gcgttactgt ttctgatctg caatacgctg cacttgatgg ctatggccgt tcaggagctg
    28561 cctatggtat tatcacaaag gatatgatcg cgatgtcagc cggataccgc gaaaaatggg
    28621 aaagcaatcc tgagccaagc ggctggtata catatcattt caaagaaact ggcaagctag
    28681 ctactgaggc cgactacctt cacagcaaaa gcaagatcaa acgaacctca aacaatagct
    28741 atgaaagcat cgtccttagc aacggtaaga ttcgcaacgg ctatcttttt gatcgtagtc
    28801 atttaattgc tgacagctta ggtggtcgtc cttttagaaa taatctcatc acaggtacac
    28861 gtactcaaaa cgttggcaac aacgaccgca aggggggtat gcagtacatt gaaaacaaag
    28921 tcctaaacta tattaaccac aaccctcagg ttcacgttta ttacaaagcc gtaccaatct
    28981 actcaggctc tgaattactc cctagggccg ttgtggtttc agcgctctcc tctgatggta
    29041 aaattgatga aaccgtaaga gtctttaaca ctgtcaatgg ctttaccatc aattaccaat
    29101 atagcggcat cagccatgat aagggcatgg aggcttctag tgagtcagaa gctgaggata
    29161 ttacagacga aagcactcca gtagctgaac cagctgatga ggaggctatg gagacagagg
    29221 ctgctgctaa cgacacaata gtctatgtta caagtaatgg ccaatcaaag gtatactggt
    29281 ataataagga ccatctgcca gagaaggtca atctcaataa ggttgtagaa atgaccgagc
    29341 aggaagccct aaatcgagga aagcaccatt cctccttaga aaaaataaat caatagtctc
    29401 ataacgacta acacaagagc tggttgaagc aaccagcttt ttttgtgtga tgaaggatta
    29461 gacagctcct tagctaaaag ataaagaggc tgataaagca ctcaacctct tatcgctttt
    29521 ataaatgctc tggtactgcg gctaatagct ctgatagctt gcttgcatca ctaccacctg
    29581 ccatcgccat atctggctta ccgccaccac gacccgacac gattggcgct aaggccttaa
    29641 tcagattgcc agcgtgagct cttttatcct tacttgcaac aagaacattg accttctcac
    29701 caatgcttgc agccagcaca aggacatctg aataatctct ttgcttccaa ttatcagcaa
    29761 aggtacgcaa gactcctgca tctgatacgg atacctcact agcaatgtaa cgtagaccgt
    29821 ttgcttcctg gaccttttta aagacatcac cagcctgagc tgctgctgct ttttctttta
    29881 gctctgccat ttctttttgc aaatcgcgga gctgctcgct gaggctcaca accttacttg
    29941 gaagctgttc tatttgcggc accttaagcg tatgtgcaat ttcttttagg atgtcttctt
    30001 gcttgcggaa gctttcaaag gcctgctgac ctgtcactgc tatgatacga cgtgttcctg
    30061 agccgatccc ctcttccttg ataatcttga aaagaccaat ttctgatgag ttggacaagt
    30121 gagtccctcc acaaagctca acagaataat cgccaatctg aacaacacga acagttttgc
    30181 catatttttc accaaagagg gccatagctc ccatagcctt tgctgtttca atatcagttt
    30241 ctgtggttgt aatagctaat gccttccaga tttgctcatt gacctcttct tcaatacgac
    30301 gcagctcctg ggctgtaacg gcttcaaagt gtgtaaagtc aaagcgtaaa aaggcttctt
    30361 catttaagga acctgcctga gtggcatgtt ctccaataac cttgtgaagg gcagcatgaa
    30421 gcagatgagt agcggtatgg tttttctcaa cagcatagcg gcgcttgtga tcaatagcaa
    30481 gagtataaac agtgtctaat gcaaggcttg caagaacctc aacagtgtga agaggctgac
    30541 cattcggtgc tttttgcaca tctatcacac gagcaacaag gtcaccctta tcatttttga
    30601 taaccccatg atcggcaacc tgaccaccca tttcagcata aaacggtgtc tgatcaaaca
    30661 caagcaaggc ctgtccttct gaaaccatct cactacgctc attatcaacg atgataactg
    30721 ataagcgaga ggcaacagtc tctgtttcgt acaaaaattc tgatggctct gtgatgcctg
    30781 ccagtgtctc attttgcatg cccattgagc cacccttaac agctgctgca cgggcacgat
    30841 cctgctgctc cttcatagct gccttgaagc cttcatgatc aatcttatag ccagcatctt
    30901 ctgctaattc ttcggtcaat tcaactggaa agccataggt atcatacagc ttaaagatat
    30961 ccttgccatc aagcctgtct tgcccctttt cctttagctg cgccagcaat tgatccaaat
    31021 gccctgatcc tgcatcaatg gtacgtgcaa aggtttcctc ctcacgcttg ataatttttt
    31081 caataaagtc acgcttctca agaatctctg gataatagga ctccatgata tgacctacag
    31141 tagctactag cttataaagg aaggtctcat gaataccgag cctacgacca tgcataacag
    31201 cacgacgaag caagcgacga agcacatagc cacgaccttc attaccaggt agggcaccat
    31261 ctccaatcgc aaatgacaag gcacgaatgt ggtctgcaat gaccttaaag ctcatgttgt
    31321 caccatcttg gtcgtaagta tggccagata gcttttccac ttccttgatg atcggcataa
    31381 ataggtcggt ttcaaagttt gtttttgcgc cctgcataac agccacaaga cgctctaagc
    31441 cagcacccgt atcaatgttt ttgtttggaa gctccttgta ctctgagcga ggaattgtag
    31501 ggtctgcgtt aaattgagac aaaacaatat tccaaatttc aatataacgg tcgttttcaa
    31561 tgtcctcttc cagcaatcta atcccaatat gatcaggatc ataagcctca ccacgatcaa
    31621 agaaaatctc tgtatcaggt cctgacgggc ctgcaccaat ctcccaaaaa ttttcctcta
    31681 atggaatcaa atggcttggc tcaacgccca gagcaatcca acgattgtaa gagtccttgt
    31741 catctgggta gtaggtcatg tataattttt cctttggaaa atcgaaccat tccggacttg
    31801 ttaacaattc aaagccccac tcaatcgctt cgtcgcgaaa ataatctccg atagaaaaat
    31861 taccaagcat ttcaaacata gtatggtgac gagctgtctt accaacattt tcaatatcgt
    31921 tagtgcggat tgacttttga gcgttggtaa tacgaggatt ttcaggaatg actgacccat
    31981 caaaatattt tttgagggtg gccacaccag agttaatcca aagcagggtt gggtcattga
    32041 ctggcacaag attggccgaa ggctcaatag agtgaccttt tgatttccaa aaatcaagcc
    32101 acatttggcg gatttgggct gatgttaact gtttcatgat taagatacca agagcgatta
    32161 gagagactgg gtatgattgt ccttagcata agtagcctgg ggagacgatc tctactcgca
    32221 ttcagttcct ttcgttgatt ttttatggga ttaggctaaa agccatcaaa acaaaacaag
    32281 cccatatcac agagggcgaa aaccgcggta ccacctctat tcaatgagct tgtcattctt
    32341 aattacttat atcagataaa atcacattaa gcagcatgcc tatcagatta tccgtaactc
    32401 acagcaaccg tcacttctct gggtcaaatc cttgataaac aattcttaac taaaccagta
    32461 taaagctttt ttgagcattc gtcaatgaaa atctattttt ctgacttaga tttagaagat
    32521 tgactatcct tgcttgagtc tgaagatgat ttctgatctg acttgcttgt gttcgccttg
    32581 cttgcttttt tatcagtatt ggcatactgt gccaagatat tagcaaatgc ttggtctttg
    32641 atcttaacat ttgccttgtc taaggccttt gcaatgacct tattttggaa atcaatgttt
    32701 tgtgtctttt cagccaagac aatttctttt agacgtttct tatatttctt ccaatcagaa
    32761 gccttttcgg cttttttggt taccttaaca atatagaact tgttttgata agtagccgga
    32821 tctaagacag aaaccacctc tgaaatatca ccctctttta atcctgaggc ggccttgatc
    32881 acatctgctg gtaacttagt gtctcctgag tcaaacttat agtctacctt cttgtctgct
    32941 gctgttgtct tttccttagc aatagcagca aagtcagcac cctcagcctt aacctcacct
    33001 aaaacagcct ttgctgtttc ttcattgtct agagtagtga cctgagtagt catttctggt
    33061 gtgtatgact cataggcttt tttgtaatca gcatctgtca gctctttttt agctgcttct
    33121 ttaacagcat attcaaccag catggctgag cgaatttgac gcttgtaggt atctgttgtc
    33181 aagccagact gcgcaagggc tgcagagaat gacgcaccgt attgctcagc tgatttattg
    33241 taagcttctt ccgttctttt cttagaaacc tttttaccgt attggtcctc aaaaacacga
    33301 ctaaccacaa ggtttagcat tgctctttga gaaatctctg tattttttgt ttcattgtaa
    33361 aaatcactaa cactgatagt gtcgcccttc atcgtaatga cacttgtatt gtcatttgta
    33421 gactgacagg ctgctagggt cattgctgat gctagggtta cgataccagc aagtaattta
    33481 gttgattttt tcatgtgatt ttgtgctcct ttttgtcatt aaccagtata ttatatcaca
    33541 atttcttaaa cgtaacttaa tctaacaaac gaatatctgc ttgattttta cgaatcatca
    33601 gcaagccatc actaagcggc agcaggctgg ctgtcaatcc aggattatca agagttgctg
    33661 caaataagtc ctgaaggcca cgataaatcg tgcgctgtcc tctccgaacc tccttgatcg
    33721 gcttagcaat gtcacccccc tgaaacacat catctaaaac aaccattcca cctattttta
    33781 agtgctttaa cacctctgga agaaactgaa tgtattttga ttttgcagag tccataaaaa
    33841 caaagtcaaa ctcgccagta agtcctgcta aaagatcagc cgcatctcct tcaagaaggg
    33901 taatttgctt gcggctatcg tattttgcaa aattttcctt ggcaaagcca atcatctcag
    33961 cattgcgatc aatcgttata atctctgcct caggagcatt ttctgccatt agcaaggcag
    34021 aaaagccaat agctgtgcca atttctaaaa tccttttggg ctgcaagctt tgcaataaaa
    34081 gcctgaaata agcaacaacc tcatgctgga taatgggaat attttcttgt ctggcaaagg
    34141 cctcaagctc tgctaaaaag ccttcgtttt gctttagctg cgttcgcatg tagtgaacaa
    34201 tgtcttcttt gacaatagag cggcgcatat tatgatttgc atttttacta tatgatttaa
    34261 ccatgctatc cattatataa aaaaactcta ggtaatgcta gggctttcac tagcctattc
    34321 acctttgacg atctgagtag tatctatcaa aggagctcac agacagcctt aagctgcttg
    34381 acaatgctat cacaagcaga caagtcctgt aagggataat caggattggc aaagccgata
    34441 caggtcatct gagcagcctt agcagcctga ctaccatgct tactatcctc aatgacaagg
    34501 caggtcttgg gatcaacgct taaccattca gcagccttaa gaaaaatatc tggcgctggc
    34561 tttgagcgag caacctcttc accactaact aacacctcaa agcagtccaa aagacctagt
    34621 gcagtgagat ttctaataat atctgcctta ggcgatgagg aagctactgc caagcgatag
    34681 cccttcgcat gcaggtgctt gattaattga gcagcacctg ctatggcctt gacaccgtca
    34741 cgctcaagca ttgcttgacg acgatgattc atctcagcga tgagggcttc aacagaatcc
    34801 tctagctgac actccttttt catagttgtc cacatatcgt caaaggtggt tcccataaac
    34861 tggtactgat acgcttcatt ggtatctatg cctcggtcca atagcatttg tgtcttggtt
    34921 gacaaaaaga tatattctga gtcaacaatc acaccgtcca tatcaaaaat aaggcttgtt
    34981 ttcatcatct acctcctctt atgctatatc tcagtcaggt caagagcaag actattaatt
    35041 actagagcta tttttaccag aaaaaagctc aacaatatct gacagctgac taatatgatg
    35101 attatcatca ctatctggca gcaataggtt gatagagcta atcccagctg cccttgctgc
    35161 agcaaggtct aagggcctat caccaatata gtaggtctgc gacttatcca tctgataatg
    35221 atgaatgaga aaaagaagcg cttcagggtc cggcttacgc ttaaagccac aatctgctgt
    35281 aatcacctct gtaaagtaat cagcaatccc cagacgctgc aaaacagcct gagtggttcg
    35341 tcctttatga gtcacaataa aaggcttaac cccctgctga gaggttaagg ctaatgtttc
    35401 cttggctgta ggcattagtg ctattaggtg atcacgcgct tcctgctctc gggtaaagaa
    35461 ggccagcaat tctgaaaaat ccagctgatg tgcctctgct aacctcttca aaagctgtcc
    35521 gatggattct tgaataatcg tatccataac ccaagcctca tcaaagggca gctgataggt
    35581 ctgatacaat aaacctagcg cctgacgaat agcctcagag gattggacta gagttccatc
    35641 aaagtcccaa atgagattaa ctgtcacaat ccttacctct taaatcaatc caataacgag
    35701 caatagcctg ccctgctaag cttgtagtag ggtaatcatc tgccacctga acaatatcct
    35761 ctaaaatacc accagccttt tcaatggttt ttcgactggc tatattatct ttattagctg
    35821 ttattaagac acgcttgatc ccacgctctt gatattgctg taatgcaaag gccagcaagt
    35881 ctgtcataat tccacgcccg cgataatctg tccttgtcac atagccaata tgtccgccaa
    35941 ttgttgctaa gtctcctttt tccaactgcc agcgacagcc tattctagcc actagctgac
    36001 catctaaaaa atagtaataa ttagtgctag tggaccagtc aggatgatca gtttggacct
    36061 caaaccgtct agattgctca acaaaggctg caaagtcctc tacttttttg gtctcaacaa
    36121 aggtattacc tgaagctttt tcagctaaca gtatatcctg aaagcgctta aaggctgctt
    36181 gatcagctaa agcaattgtt ctaatctctt tcatgcctgg ctccttttta ttatgctaaa
    36241 aatcaactgg gcatttctca agcattcatc atgccaacga aaaagagctg cccctagaac
    36301 tgttgatgta atactacgtc tagaggctgc ccacaggcct ttaagctagg ctgatagaca
    36361 ctgactgctg ctatttacca atagctcaaa acctaagagg agatggcaac tattagagat
    36421 gtgcccctct tgccactaag tcctctagct ctgtcaaacg ctcttcaaag accctaaagg
    36481 ctgcttctag gtaatcaccc ttagccatat caacaccagc cttggcaatc acctcaagcg
    36541 gataatctga atttccagac ttcagatagg tcaagtagtg atcaatatcc tcttgagtac
    36601 catgcacgat cttatcagcc aagtagctgg ctgcagcaaa gcctgttgca tattgataga
    36661 catagtagtt gtaatagaaa tgcggaatgc gagcccactc atactggata aaatggttgt
    36721 cctctttttt taagccataa tatttttcgt ttaaatcagc atagagatta ttgaggtatt
    36781 cacttgttaa cacctcgcca ttttgatccg cctgatgaat agcgtgctca aactcagcaa
    36841 actgtgtttg acgaaaaacc gttccacgaa aaccatctag gtaatgattc aaaatagcaa
    36901 agcgctcctt atcatcctgc acctcatgta acaaggcctc agtcatgata ttttcattag
    36961 tggttgaagc aatctcagct aagaaaatgc tgtaatctcc atacacgtaa ggctgtgttt
    37021 cacgcgtaaa ggttgagtgc aggctatggc ctgtctcatg cactagcgta tagaggttat
    37081 caagcgtgtc ctgccaattt aagagcataa aggcattggt atcataggaa ccaccagagt
    37141 aagctcctga gcgtttgccc ttattgacat gcacatcaat ccaacgctct gtaaaggcac
    37201 gatgcacacg ctctgaataa tcctggccaa aaacagccaa aaccttctct gctttttcca
    37261 aggcctcatc atagccgata gcaagatctg tctcagataa aggagtataa acatcataca
    37321 tctttagatc atctaaacca agcacctctt gacgtagctt caaataacga tgaagcagcg
    37381 gcaaatgctt attaacgttt tctagtaggg tatcgtaaac agcctctggg ataaagttgg
    37441 ctgacatcgc tgcctgacgg gctgaagcat atttgtgaac acgtgcctta taattttgca
    37501 cctttacatt ggtttgcagg gttttagcat aggtgtgctg gaattgctca taagtactat
    37561 acatggcttc ataggcagcc ctacgcacct tgcggtcttt cgattccatc aagctaatga
    37621 aattaccatg tgttagctca acctcttctc ccttatcatt tgtcacaata ggaaaagcaa
    37681 tgtcggcatt atctaggata ctaaaggtct cctcagcacc attaaagatt tcttgtgccc
    37741 ctgctaatag ctcctcctca gcctgactaa ggacatgctc acgcgtcttg aacaatttat
    37801 caaagaaatg gtcatagact gttagctccg gtgtctcagc taagaaggct tggtaggctt
    37861 cctgacttaa ggccataaat tctggctcat agaatgaaaa ggcttcacta aatttagcat
    37921 aaataccaga ggccttagct tgatattctt gatacttggc aactgtcgta tcctgatcat
    37981 ttttcatgct agcataaaca taaacctttt caacacgacg agccagctcc aaatgcagct
    38041 ctgtgatatc taagagactg ctgcttgaat ccaacaaatg cccagcctgc tgccttgcag
    38101 cctcaattgc tgccagcaga ctatctgcct ctgtctccca agctgcgtct gttgcaaaaa
    38161 tagtgcttaa atcccaagtg tacttttcct ctagatgact acgattatct gtcatacgga
    38221 cctcctaagt ttctattact aatcatttta acataatatg ctggtgaaaa aagcttttgc
    38281 acctctttat ttgctgcttt tgcgtaatat ttttcaaagc aatcgtaata gtggctcaaa
    38341 tcctcatgaa tctggcaaaa gccagctgag caagcaatcg gcttaacctg tggataataa
    38401 gcctctaggg gcctatcaag caggttatcc ccagctagat aagcctcttc ttgctttttc
    38461 aaccatttgc tatcttttgc tagtaaggct ttttgaatcc ttctcagcaa gtgcttatcc
    38521 atctggagct gataggctga caggcctttt ctttggtaag gcagccgcaa aaaggccaac
    38581 aaatcatcat ctaaggaaca ggtctttact agatagctga ccttaccaaa taaatcctca
    38641 tgaatc
//
LOCUS       DARYNN010000017        38112 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.017, whole genome shotgun sequence.
ACCESSION   DARYNN010000017 DARYNN010000000
VERSION     DARYNN010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38112)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38112)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38112
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.017"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(80..1285)
                     /locus_tag="TVB59_000790"
     CDS             complement(80..1285)
                     /locus_tag="TVB59_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HEL1009716.1"
                     /translation="MKISVAGSGYVGLSLSILLAQHNDVTVVDIIDEKVRLINQGISP
                     IKDADIEEYLKNAPLNLTATLDGASAYSNADLIIIATPTNYDSERNYFDTRHVEEVIE
                     QVLDLNASATIIIKSTIPLGFIKHVREKYQTDRIIFSPEFLRESKALYDNLYPSRIIV
                     SYEKDDSPRVIQAAKAFAGLLKEGAKSKDTPVLFMGSQEAEAVKLFANTFLAMRVSYF
                     NELDTYSESKGLDAQRVIEGVCHDQRIGNHYNNPSFGYGGYCLPKDSKQLLANYRGIP
                     QSLMSAIVESNKIRKSYLAEQILDRASSQKQAGVPLTIGFYRLIMKSNSDNFRESAIK
                     DIIDIINDYGVNIVIYEPMLGEDIGYRVVKDLEQFKNESTIIVSNRFEDDLADVIDKV
                     YTRDVFGRD"
     gene            complement(1538..2791)
                     /locus_tag="TVB59_000791"
     CDS             complement(1538..2791)
                     /locus_tag="TVB59_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEL1009717.1"
                     /translation="MRTLKNLITVVAFSIFWVLLIYVNVYLFGAKGSLSIYGFLLIAY
                     LLVKMSLSFFYKPFKGRAGQYKVAAIIPSYNEDAESLLETLKSVQQQTYPLAEIYVVD
                     DGSADETGIKRIEDYVRDTGDLSSNVIVHRSEKNQGKRHAQAWAFERSDADVFLTVDS
                     DTYIYPDALEELLKTFNDPTVFAATGHLNVRNRQTNLLTRLTDIRYDNAFGVERAAQS
                     VTGNILVCSGPLSVYRREVVVPNIDRYINQTFLGIPVSIGDDRCLTNYATDLGKTVYQ
                     STAKCITDVPDKMSTYLKQQNRWNKSFFRESIISVKKIMNNPFVALWTILEVSMFMML
                     VYSVVDFFVGNVREFDWLRVLAFLVIIFIVALCRNIHYMLKHPLSFLLSPFYGVLHLF
                     VLQPLKLYSLFTIRNADWGTRKKLL"
     gene            complement(3188..3808)
                     /locus_tag="TVB59_000792"
     CDS             complement(3188..3808)
                     /locus_tag="TVB59_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009718.1"
                     /translation="MRKYLQIRLYELSHYVEIIISIILVISLLVLTGRLALSLTGIFT
                     IKSGIDTYLQSFLNQAMSIAIGVELIKMLSKHTSGTIIEVLLFAIARQIVVAHGSAKD
                     SLLSVIALAILFATRKYLFTSFDDTSSIIVRGSQKVKIANVLARVELPVINKNELMRD
                     LMLRHLEEEGKTATIGASIAFSDVALRVDHMHEGVITRIEIIKSLK"
     gene            complement(3849..3944)
                     /gene="ffs"
                     /locus_tag="TVB59_000793"
     ncRNA           complement(3849..3944)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="TVB59_000793"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            4121..5347
                     /locus_tag="TVB59_000794"
     CDS             4121..5347
                     /locus_tag="TVB59_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein"
                     /protein_id="HEL1009719.1"
                     /translation="MKNKLSLFLLAALTIVGLSACAWRSNPLADKEQQFGLTGARRQQ
                     VLDQIDQRYYYQQLSQAEKENYLLLYDSLSAFHEVTSLAPASKHSLMTTIDAFMMDNP
                     AFFWITSANYRLERSDQVAFVTFPLPEKVEQTYHRLQAIGDDIIADMPATNDYERVRY
                     FYEWIIKQTDYNRDAFEAYQSGHEALIASNQDIRSVFLDHLSVCNGYAQAFQFLCQKA
                     GIPVAYIRGSVTFDRSQDVFTHAWNTVQIAGKNYAVDTTFGDPVFDQNESIKQLEVNY
                     NFLCLPDQLMKQSHQASRDIVINQTETLTDVWTIPECSDDSLLYTKLNHSYFTAFDRP
                     DILASLEQQLRTNQPQTSLQFANQDLYNQMVSDLEQHSDSYHSLFQAYWPNAAGYFYS
                     LHPSTFSISISIINQQ"
     gene            complement(5457..5951)
                     /locus_tag="TVB59_000795"
     CDS             complement(5457..5951)
                     /locus_tag="TVB59_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEL1009720.1"
                     /translation="MSYSKQEQEYFMREALKEAEKSLLKDEIPIGCVIVKAGHIIGRG
                     HNAREERNQAIMHAEIMAINEANAHEGNWRLLDTTLFVTIEPCVMCSGAIGLARIPHV
                     VYGASNQKFGGAGSLYQILTDERLNHRVQLEVGLLADDCAKLMQTFFRQRRDQKKQDK
                     ESKI"
     gene            complement(5948..6730)
                     /locus_tag="TVB59_000796"
     CDS             complement(5948..6730)
                     /locus_tag="TVB59_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEL1009721.1"
                     /translation="MKLTTLGSWGAYPYQDAGTTAYLVTGHDGFQLLMDAGSRSLNEL
                     EKEINPLDLDAVIISHYHPDHVADLGVLRHYYQLYPRHLGKPRLLPIYGHDEDEAEFA
                     KLTLPGVSKGIAYQVDRVEALGPFDITFIKTVHPVVCYAFRIVERATGQVLVFTGDTG
                     YFEELADFAAEADVFLADVYLYEGNEHHMAHLTSKEAGQLASRAKVKRLVLTHMPPLP
                     PEGIDPKRHLEVLRQQAQGYAGQIPVDLALPHRAWDLGSLSQ"
     gene            complement(6829..7368)
                     /locus_tag="TVB59_000797"
     CDS             complement(6829..7368)
                     /locus_tag="TVB59_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEL1009722.1"
                     /translation="MLSTKDLVKVAMMTTLIIILGLIPAIPLGFVPVPIVLQNLGVML
                     AGLILGGKKGTLSILLFLVIGLFLPVFSGSRTTVPVLMGPSAGYVLAWLFVPLVFAFL
                     YRSWLARYRSLAFLAIFISGVLLVDLLGTIWLAVYTDMPLTRSLVASLVFIPGDTIKA
                     VIATALAVSYKDSFLNTNS"
     gene            complement(7372..7683)
                     /locus_tag="TVB59_000798"
     CDS             complement(7372..7683)
                     /locus_tag="TVB59_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009723.1"
                     /translation="MRNCFGIALDQEYRCVHYHTVLDIVGLKCARCQAYYACYHCHDT
                     LQDHAFEPTDHKETYPVICGHCRQLLRRSEYECGSCPFCFSPFNPAYHKHQDIYFSKE
                     L"
     gene            complement(8070..8207)
                     /locus_tag="TVB59_000799"
     CDS             complement(8070..8207)
                     /locus_tag="TVB59_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003585727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL1009724.1"
                     /translation="MHQNPTERSVLLSTYEALQLMLAFGSFLLTLISLVVAIVILNNK
                     K"
     gene            complement(8591..9835)
                     /locus_tag="TVB59_000800"
     CDS             complement(8591..9835)
                     /locus_tag="TVB59_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1009725.1"
                     /translation="MRNKKTSIRLVQKYGICSAVVALATIASLGIGNDVRAEDFTYPS
                     MYNQGYFFQQFIKKEILNPGSGSSSDWETSTHYNNGRMLENVLRYLWRVEQFLKKSTG
                     QSEQLYKLYEKDSLGIPGPQGPMGPAGPQGLRGERGPVGERGPIGPQGPEGKPGQQGP
                     KGDTGPQGEPGQQGPKGDIGPQGEPGLPGPKGDTGPQGAPGQQGPKGDTGPQGEQGLQ
                     GPKGDTGPQGAPGQQGPKGDTGPQGEPGQPGPKGDTGPQGEQGLQGPKGDTGPQGAPG
                     QQGPKGDTGPQGAPGQQGPKGDTGPQGVPGQQGESQKVPEVPKAPETPEKKEQPQAPK
                     EPETPKAPEQSPAPQAPKSSEQPASPKAPAPQSAPNKSAAPAAQKGTLPATGEANHPF
                     FTLAALSVIASAGVLGLKKKQD"
     gene            complement(10265..11407)
                     /gene="tgt"
                     /locus_tag="TVB59_000801"
     CDS             complement(10265..11407)
                     /gene="tgt"
                     /locus_tag="TVB59_000801"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEL1009726.1"
                     /translation="MTNYPITYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEIGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQAILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAADLVSMDFPGYSI
                     GGLAVGESHAEMNAVLDFTTPLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSEGRLVVKNAKFAEDFTPLDHHCDCYTCQHYTRAYLRHLLKADETFGMR
                     LTSYHNLYFLVNLMKQVRQAILDDNLLEFRQDFLERYGYNSSSRNF"
     gene            11812..12657
                     /locus_tag="TVB59_000802"
     CDS             11812..12657
                     /locus_tag="TVB59_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEL1009727.1"
                     /translation="MSIREIKREARQTLKGLKGKYLLFLVPIILSIFYSGIEVHQTYV
                     TTQGIEVSVGASYFPLIVLIMLTVFTLSAAYTMLDVIRYYRREVSFSEATIAFSGNLF
                     GKVLVLLIIKGLLFILWSLIWIVGLVILTISSAALLTSYNTGAAVMTPIIFMVIGFVI
                     FIIGLIVYMNRYCAYSMAEYILYDKVKEGTYMGAITAIEESKDMISGYKGKYFLLHLS
                     FIGWFILVILSFGLIYIYVLPYYTTADVTFYHHLKHIHDETELPIDAERLTITGSKEA
                     PSAIS"
     gene            complement(12853..16815)
                     /locus_tag="TVB59_000803"
     CDS             complement(12853..16815)
                     /locus_tag="TVB59_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NPCBM/NEW2 domain-containing protein"
                     /protein_id="HEL1009728.1"
                     /translation="MFKPYTDGKQRFAIKTFKTGAASVLVATLFLTLGLTTVSADEQQ
                     VTASAAIATTLEAQEAVDQQAADQSATAAQDTAAEGSSETLPVVIGTATTETTDSKSQ
                     VAAAEQATEASAEETTKQEQTEVSQAVETTNKTEAKDYIYLSDETRVNPSKVGHGSFL
                     QDKNPAGGTITLVVDGEVLAFDKGIAVHAPSQLYYDVEQYSNEYTRLSAYLGVDYSRR
                     GKDDGVSFNIYKSKDGKSWESLVTTGTVTGTSEAVYVDLDITGAKYVKLIANSLKNNG
                     NDHSVYADLRLLKTDYDLSSEVSYDRLKTTEEYDALLSKNSVTDNYDNPDNLALVLER
                     EFVNRVGYHTIQSAVKKNEKVKVALDWLLSDEDALSLFLEAGSMFNGSTLKTLNALGD
                     LYATNKADLEDKGNGYVYKKMMLATAVAYCKEIKSFVVNYGGTYLASDPVLKYQAFKE
                     LYRDNEFLRKEEFANYNMELVRAVMDAKIDDEEILWLHHYAEQKYGDKVASYTSGYSY
                     TKYKNIGYGGADMRSADNQAQWTEKYQLVGTLNDDAFNVTYDNRHRIWMLMEKGAVCW
                     GLSNLGVAVNEVFGIPAVNIYQNDHEAYLVYRQDDQGNGIWDIRDNVYGNRWAISYSR
                     WGTTTATEARLLLGWGLKSYNDIHKNASYMLLAQAALNQYDKFKESLYYNLIANVYEA
                     GSDQQIEAYSKALDVLELNLDTYDGLIEAYAKNGQKTDQDWLDLGKRVIAAYTYYPQV
                     MVEAIKRITPNISDQAAKAELDLLSYNALIAAKTATDKEVLQSNEVRIIANYILTGNP
                     IETASFSFDDKTLRLHENYQDTDLTVRYSIDNGKTWLETKDKVIVFSDDLLAKLNIED
                     GILVGFDAVSATYRINLTKAAAPTNSSLYGNDLENRLIGAIEHLEVSLDNGQSWQAYD
                     GTERFNDTVTVLARYRAHGTSLASDSVTYTFTADSTDPTMHYISIDDIQAVTYANEQS
                     GRSGKHMVDGRDMATQWHTLFNQVTEDKSYTVEFKDDKNFSAIAYLPGGVNGMIHSAK
                     VDISSDGKVWTTVVDSTDWKQNTELKTVSFTPTTGRFVRITALDTYGKSSGQANKFVS
                     GSAYRFFEDISSPIEAPVRNDILALKDSILTILKETNTATKEIESFAITNSGLTAATT
                     EKNQAIQGKILETIKDLGLTGTYYITLENTGTYDDLADLLNHQLVITYQDKAAGPLYV
                     LAMNSLSSGDEALDAEYSLDLIKSALKSALESENIDLKTFEGLSISSQLPAAKTAVNT
                     ALMEKLQQLLPGDYFIDLAGLPTAASIDELLDSQLFIYYRESHWTTAYALDRGAFQQL
                     "
     gene            complement(16950..18767)
                     /locus_tag="TVB59_000804"
     CDS             complement(16950..18767)
                     /locus_tag="TVB59_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HEL1009729.1"
                     /translation="MKKFTKRCLKGCGLVGLVFSTGLVALSDNIDSALTVGAETTTAS
                     AFENNGTGQHLNWHIDIPQEYTVELGEPITISDLMSQITVTRKGSNGTVNDGDTFDFI
                     SNGDGSRGIDTPGVKIWFDFYNAAGTSFLTDEMLASPTYAVPGGSYTIKAWVFYGKND
                     TKKLFTFKLKNSNSNKTELRKSLEEAKLKLSQPEGTYSDESLQALQSAVTIGKTYLNS
                     DPDQNTVDQSVTTIDSAITSLVNLNALNEAINQATPFITDGKEYPKEAYDGLVQKLAA
                     AAKLQNSFGPSQGDVDKAATDLTQALTTLKTAVAHEALDQALAKLLELYRENPNLALT
                     SESLKELYNKAIEAAGTFYRTVNKDKERKDISLYELERYTTETNSVVDTILKVKAAIA
                     EEGKAKLRSALDQLNALIGENLDLSPYTAASAQAYTDQLAKAKEVAAAGETAYAQETE
                     PTAITNSLVKVLNAKKSLSDAKAALVAKPVDPVDPVDPVDPVDPVDPVDPVDPVDPVD
                     PVDPVDPVDPVDPVDPVDPVDPIDPADPVKPSDPEVKPEPKPESKPEAKKEDKKAADK
                     QQVLPATADTANPFFTAAALAVIACAGQLAIVSRRKESN"
     gene            complement(19127..19600)
                     /gene="perR"
                     /locus_tag="TVB59_000805"
     CDS             complement(19127..19600)
                     /gene="perR"
                     /locus_tag="TVB59_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide-responsive transcriptional repressor
                     PerR"
                     /protein_id="HEL1009730.1"
                     /translation="MDIHSHQQALNAYENVLEHLRDKHIRITETRKAIISYMIQSTEH
                     PSADKIYRDLQPQYPNMSLATVYNNLKVLVDEGFVSELKISNDLTTYYDFMGHQHVNV
                     VCEVCGTIADFMDVDVMDIAKEAHQQTGYKVTRIPVIAYGVCPSCQTKQGKDTDY"
     gene            complement(19637..20089)
                     /locus_tag="TVB59_000806"
     CDS             complement(19637..20089)
                     /locus_tag="TVB59_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEL1009731.1"
                     /translation="MIDTFQNPSDETITSYLESSKTIAVVGLSDRQTTAAYDVARFMQ
                     AKGYRIVPVNPRLAGQSVLGEVVYASLAAIPFKVDIANVFRRSEYLPQVAQDFLACQG
                     QVFWAQLGLYSQEAEELLRSAGKADIVMNRCIKIDYLRLISKQDQDSC"
     gene            complement(20329..22971)
                     /gene="polA"
                     /locus_tag="TVB59_000807"
     CDS             complement(20329..22971)
                     /gene="polA"
                     /locus_tag="TVB59_000807"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEL1009732.1"
                     /translation="MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGF
                     HLMLDHMMKRVQPTHVLVAFDAGKTTFRTELFADYKAGRAKTPDEFREQFPYIRDMLG
                     ALGIAFYELEHYEADDIIGTLDKMAERTEIPFDVTIVSGDKDLIQLTDANTVVEISKK
                     GVAEFEEFTPAYLMDKMGLTPEQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEYGS
                     LEGIYEHIDSFKPSKMKENLLHDKEQAFLSKTLATINTSAPITIGLEDIVYQGPDLDR
                     LSQFYDEMDFVQLKNALASQLPQEPVAEIAYQEVTDIRADMFSDDTVFYFEALRDNYH
                     REELIGFAWGNQGQIYASADISLLTTKLFKKVLEQPIATYDFKRSKVLLSHLGLDLPA
                     ASYDARLANYLLSTVEDNEMATLARLYTTISLDTDEVVYGKGVKRAVPDKAVLLGHLA
                     RKVQVLLDSRPVMLDKLAEHEQADLYTDIELPLANVLAKMEIEGIAVNQDSLQEMAEQ
                     NKVVIEELTQEIYEMAGEVFNINSPKQLGVILFEKMQLPLHLTKKTKTGYSTAVDVLE
                     RLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIMADGRIHTRYLQDLTQTGRLSSVDP
                     NLQNIPIRLEQGRLIRKAFTPSHDDAVLLSSDYSQIELRVLAHISGDEHLIAAFKEGA
                     DIHTSTAMRVFGIEKPEDVTANDRRNAKAVNFGIVYGISDFGLSNNLGIPRKQAKAYI
                     DTYFERYPGIKAYMERVVREAKDKGYVETLFKRRRQLPDINSRQFNVRSFAERTAINS
                     PIQGSAADILKIAMINLDQALVAGGFETKMLLQVHDEIVLEVPNHELAAVKALVKETM
                     ESAVSLAVPLRVDESAGKSWYEAK"
     gene            complement(23395..25125)
                     /locus_tag="TVB59_000808"
     CDS             complement(23395..25125)
                     /locus_tag="TVB59_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HEL1009733.1"
                     /translation="MENLLQTTLPVAQLVEQLTEWLTKTFSGFFDLLQLVGNALMDWI
                     TQTLLFINPLLFMLLVTCAMFFLARKKWPLPIFTLLGLLFVYNQGLWAELINTFTLVL
                     VASLISVLLGIPLGIWMAKNKIVHQVINPMLDLMQTMPAFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLALRHIPTELVEASDAFGSTPKQKLLKVELPLAKHTMMAGVN
                     QTMMLALSMVVTGSMIGAPGLGREVLSALQHADIGRGFVSGLALVILAIILDRMTQHF
                     NGKPQERTQTGKTKKWLGLAALAVFLLSALGRGFAAMLSSSADKGQKVTIAYVQWDSE
                     VASTHVIAQVLRDEGYQVTLTPLDNAVMWQTIANGDADFSTSAWLPVTHQQQYQKYQD
                     KLDNLGPNLKGTKLGLAVPAYMSDVNSIEELSDQANQQIIGIEPGAGIMTAADKTQKA
                     YSNLADWELVAASTGAMTTSLDQAVKKKEPIVVTAWSPHWMFAKYDLKYLADPKKTFG
                     SKENINTIARRGLKADLPAVHRIVDHFHWEKEDMEAVMLDINQGMTPEAAAKKWVASH
                     ADKVAKWTQS"
     gene            complement(25143..26339)
                     /locus_tag="TVB59_000809"
     CDS             complement(25143..26339)
                     /locus_tag="TVB59_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HEL1009734.1"
                     /translation="MGTILEVRHLSKLFGKKQKAALEMIKAGKSKSAIFKKTGVTVGV
                     YDASFEVQEGEIFVIMGLSGSGKSTLVRMLNRLIEPSAGSILLEGRDISKLSVDQLRE
                     VRRHDMNMVFQSFALFPHKTILENTEFGLELRGVPKQERREIAKRALDQSGLLEVRDQ
                     YPDQLSGGMQQRVGLARALANSPKILLMDEAFSALDPLIRRDMQDELLELQETMKQTI
                     IFISHDLNEALRIGDRIALMKDGQIMQIGTGEDILTNPANDFVREFVEDVDRSKVLTA
                     QHIMIKPITTTVDLDGPQVALNRMHNEEVSMLMATNRRRQLIGSLTADGAIEARQKKL
                     PLSEVIDRNVRTVSKDTVITDILPLIYDSSAPIAVTDEQHRLLGVIIRGRVLEALANI
                     PDDDLN"
     gene            complement(26538..26780)
                     /locus_tag="TVB59_000810"
     CDS             complement(26538..26780)
                     /locus_tag="TVB59_000810"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009735.1"
                     /translation="MTSSYGQSKLTLCLADLIAIGSLLGSLSIGLVAGQESDRSIKSA
                     RGGCWVSSQGAKCQKGLLAVVCSGLLSAWLTSDITA"
     gene            complement(26845..27936)
                     /gene="ulaG"
                     /locus_tag="TVB59_000811"
     CDS             complement(26845..27936)
                     /gene="ulaG"
                     /locus_tag="TVB59_000811"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEL1009736.1"
                     /translation="MAKVQDITRESWILSTFPEWGTWLNEEIEEEVVPEGNFSMWWLG
                     NCGIWIKTPGGANVVMDLWSNRGKATKKVKDMVRGHQMANMAGVRKLQPNLRAQPMVI
                     DPFMINELDYYLVSHYHSDHIDINTAAAIINNPKLDHVKFVGPYECGKIWESWGVPKD
                     RIIVVKPGDSFAFKDIKVTAVESFDRTCIVTLPVAGAEENGGELAGLPVTDEELARKT
                     VNYIFETPGGTIYHGADSHFSNYFAKHGRDYDIDVVLNNYGENPIGIQDKMTSVDLLR
                     MAENLRAKVVIPVHYDIWSNFMASTDEILELWKMRKERLQYQFHPFIWEVGGKYTYPQ
                     DQDRIEYHHPRGFDDCFLEDSNIQFKALL"
     gene            complement(28131..29777)
                     /locus_tag="TVB59_000812"
     CDS             complement(28131..29777)
                     /locus_tag="TVB59_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEL1009737.1"
                     /translation="MIILDKKSYDLLSYLIRLKEAETVMAISAALGQSRRKIYYHLDK
                     INEALPSHVAQIVSYPRVGILLNSEQKAACQQLLNEVADYHYVMKGDERRSLSAIYIA
                     VATERVTLDKLMMINDVSRNTILNDLAELREELSSYNNKIQLHATKAKGYYFDCHPMA
                     LIQYLYKVLAGVYQGGNSSFIELFDHKLSETQGLSAYFSKEVLDYFHEYLFLSQASLG
                     KTINIQDSQFMLQILPFILLSYRNMQLHSETKTALKRDFNLIWKRKEYQIAKALASEL
                     YHNFKLHLDDIEVGMIAMLMLSFRKDQDHHVESQDYEQMRATIGDFIDQLELRYQLHF
                     THKKDLLRQLTRHCKALVYRKAYGIFSINPLTDHIKEKYEELFAMAQSCAVILEQAWQ
                     IRLTDDDVAYLTIHLGGELRHSHADWDKTKLVIVSDDGIGIQKLLLKQCQRYLPNCQI
                     EAVFTTEQYQSVFDLMSVDIVVSTTDALEALVPVLIVNPILSDDDIIRLIRFSKQGRL
                     SDSSRFSLELEKAIETIVKDDADRYALKTKIEKLIHHELL"
     gene            complement(30081..30797)
                     /locus_tag="TVB59_000813"
     CDS             complement(30081..30797)
                     /locus_tag="TVB59_000813"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEL1009738.1"
                     /translation="MAKRLQEMRERVCAANKALPLHGLVKFTWGNVSEVCRELGRIVI
                     KPSGVDYDQLTPENMVVTDLDGTIVEGELNPSSDLPTHVQLYKAWPEVGGIVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGPIPCARSLTADEVNGAYEKETGTVILEEFASRGL
                     DPMAVPGIVVRNHGPFTWGKTPELAVYHSVVLEEVAKMNRLTEQINPRVEPAPTYIMD
                     KHYLRKHGPNAYYGQKGSRH"
     gene            complement(30797..31660)
                     /locus_tag="TVB59_000814"
     CDS             complement(30797..31660)
                     /locus_tag="TVB59_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003100317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEL1009739.1"
                     /translation="MARPIGIYEKATPKHFTWLERLQFAKVLGFDFVEMSVDESDARL
                     ARLDWSKQERLDIVKAIYETGVRIPSICFSGHRRYPLGSSNPETEATSLELMKKCIVL
                     AQDLGVRTIQLAGYDVYYEEKSPETRARFIKNLRQACTWAEEAQVILAIEIMDDPFIN
                     SIEKYLAVEKEIDSPYLFVYPDTGNVSAWHNDLWSEFYNGHRSIAALHLKDTYAVTET
                     SKGQFRDVPFGQGCVDWEAMFDVLKKTHYHGPFLIEMWSENCETVEETRAAIKEAQDF
                     LYPLIEKAGLS"
     gene            complement(31665..32330)
                     /locus_tag="TVB59_000815"
     CDS             complement(31665..32330)
                     /locus_tag="TVB59_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEL1009740.1"
                     /translation="MMTHIPKLQVALDHSDLQGAVRAAVAVGHEVDVIEAGTVCLLQV
                     GSELVEVLRSLFPEKIIVADTKCADAGGTVAKNNAKRGADWMTCICCATIPTMAAALK
                     AIKEERGERGEIQVELYGDWTYEQAQLWLDAGISQAIYHQSRDALLAGEVWGEKDLNK
                     VKALIDMGFRVSVTGGLDINTLKLFEGVNVFTFIAGRGITEAEDPAAAARAFKDEIRR
                     IWG"
     gene            complement(32425..32910)
                     /locus_tag="TVB59_000816"
     CDS             complement(32425..32910)
                     /locus_tag="TVB59_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEL1009741.1"
                     /translation="MNLKKAFIENNSIRLGLSAASWQEAVKLAVQPLIDSGAVTSEYY
                     DAIIASTEKYGPYYVLMPGMAMPHAEAGVGVKRNAFALITLTKPVTFSDGKEASVLLT
                     LAATDPSIHTTVAIPQIVALFELEDAISRLVACHTPAEVLALVDESKNSPYLEGLDLD
                     S"
     gene            complement(33126..33404)
                     /locus_tag="TVB59_000817"
     CDS             complement(33126..33404)
                     /locus_tag="TVB59_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1009742.1"
                     /translation="MVKVLTACGNGMGSSMVIKMKVENALRQLGVTDIQSASCSVGEA
                     KGLASGYDIVVASNHLIHELDGRTKGHLVGLDNLMDDNEIKTKLQAVL"
     gene            complement(33519..34952)
                     /locus_tag="TVB59_000818"
     CDS             complement(33519..34952)
                     /locus_tag="TVB59_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL1009743.1"
                     /translation="MKMLIAPLNWFSQDILQNPAFFVGLLVLIGYLLLKKPLHEVFAG
                     FVKATVGYLILNVGAGGLVNTFRPILVALGKKFELKAAVIDPYFGLAAANTKLEEMGS
                     ISVATTALLIGFGVNILLVALRKVTKVRTLFITGHIMVQQAATISVFVLLLIPQLQNA
                     FGAWAVGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAPFFGKKE
                     ENLDNLKLASFLTIFHDTVVASATLMLVFFGAILAVLGPDMMSNAELIGAGAFNPAKQ
                     AFFMYILQTSLTFSVYLFILMQGVRMFVSELTNAFQGISSKLLPGSFPAVDVAASYGF
                     GSSNAVLSGFTFGLIGQLITIALLVIFKNPILIITGFVPVFFDNAAIAVYADKRGGWK
                     AAVALSFISGILQVALGAVAVGLLGLTGGYHGNIDLVLPWLPFGYLFKFLGIAGYVVV
                     CVFLLAIPQLQFARAKDKEAYYRGEAQ"
     gene            complement(35435..36055)
                     /locus_tag="TVB59_000819"
                     /pseudo
     CDS             complement(35435..36055)
                     /locus_tag="TVB59_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003104274.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(36057..36674)
                     /locus_tag="TVB59_000820"
     CDS             complement(36057..36674)
                     /locus_tag="TVB59_000820"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009744.1"
                     /translation="MKLSNLLVVGMKACLTGLLIHLLLIKANMTGERDFHNLVCYRLL
                     MPFPVIEGETADFVKVITLLGLSFNSFYFTISFLADLAEGTKEIFRFHARSQLVFFNK
                     LWRTSTIFYIKEWLLFIVLILGVLMTYYGAPYHIERLCYLMVSWLTIDICLIYVMIRY
                     ASSAVVAMILFASLTLIRYFLFDVWWCLLLIVLVHMLYDNYYKES"
     gene            complement(36661..37449)
                     /locus_tag="TVB59_000821"
     CDS             complement(36661..37449)
                     /locus_tag="TVB59_000821"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009745.1"
                     /translation="MLQYRLFPFRYFYPLVPLLFLGFIYFDSLKHILFFDTSAVDLSG
                     GIEVKKSLLLSMIRLDSVVFDFSFYQSFIYPLVMILVAYAYYYLKSRHLKYLIGRKSD
                     YGKRCIFLKLQLSLYVLLSFYIVIFALTLVSWLNGVAHMNGNLMPYFDQNSILRFFGQ
                     GATTFIAYYCLVKSLALFVHTYFVCFLVDYLQSFIKSSMLYLILMWALSPLLYSYLPP
                     KYVLMTSLMSTSYSDADIPYLLSPYLGLVGVCIVLKLRKHHEII"
     gene            complement(37520..37921)
                     /locus_tag="TVB59_000822"
     CDS             complement(37520..37921)
                     /locus_tag="TVB59_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009746.1"
                     /translation="MKLGKIKIGLLAIVASTLLISSLVIAERQIGYLQNFRITSSFGR
                     TKDYLVKSAAPYYVVNLDSRGRNREIVVRHYLANSNGQRRSDIDKTWTGDRGIYTQDT
                     KSGYLYALHLVRENWWDGATTISGSWSPDNW"
BASE COUNT        11007 a         8919 c         7426 g        10760 t
ORIGIN      
        1 tgggataatg gcttttctga cctttgtcat gagttcctcc ttgatttgtg gttccttatg
       61 tgtgccactt gttttctgac tagtctcttc caaagacatc tctcgtgtaa accttgtcaa
      121 tgacatctgc taggtcgtcc tcaaagcgat ttgacacaat gattgtagac tcgtttttga
      181 actgctctaa atcctttaca actctatagc caatgtcctc accaagcatg ggttcgtaaa
      241 tgacaatatt aaccccatag tcgttgatga tatcaataat atctttaatg gcgctttctc
      301 ggaaattatc agagttgctt ttcataatca agcggtaaaa gccaatcgtt aatggtacac
      361 cagcctgctt ttgactagag gctctgtcta atatttgttc agccaaataa gattttcgta
      421 tcttgttgga ttcaacaatc gctgacatca aggactgggg aatgcctcta taatttgcca
      481 acagctgctt gctgtccttt ggcaggcaat agccgccata tccaaaggaa gggttattgt
      541 aatggttacc aatgcgctga tcatgacaga ctccttcaat cacgcgctga gcatctagac
      601 ccttgctttc ggaataggtg tctaattcat taaagtaaga cacccgcata gccaaaaagg
      661 tattcgcaaa tagcttgacc gcctcagcct cctgtgagcc cataaataag accggagtat
      721 ccttgctttt ggctccttcc tttaaaagac cagcaaaggc tttagcagcc tgaataaccc
      781 ttggtgagtc gtccttttca taagaaacaa tgattcgact tgggtaaagg ttatcgtata
      841 aggcttttga ttctcttaaa aattctgggc taaaaataat acgatctgtc tggtattttt
      901 ccctaacatg cttgataaag cctagtggta tggttgattt gataataatg gttgctgacg
      961 catttaggtc taggacctgc tcgatgacct cttcaacatg ccttgtgtca aagtagttgc
     1021 gttcgctgtc ataatttgtc ggagtagcaa tgataataag gtctgcattg ctataagcgc
     1081 ttgcgccatc aagcgtcgct gtgagattta gcggcgcatt ttttaaatac tcctcaatat
     1141 cagcatcctt gattggcgat atgccttgat tgatcaatct caccttttca tcaataatgt
     1201 caacaacagt gacgtcatta tgttgtgcca gtaaaatact caaggatagg ccgacatatc
     1261 ctgagcctgc tacagaaatt ttcacttcat tttttccttt gataccttag tacagttagc
     1321 tactgccgga gctcaggtgc cacacctgaa ggaccatgat gacctagccc tcataccaaa
     1381 gctgacgctc agcctctggt tcgtcttcac agggctacaa gctaaaagct cttaactcaa
     1441 gtacaagtgg actagcttta tttgatgagc tgcttaactc aagatgcttt gttcactcct
     1501 agcttagctc ccttgtcaga acctaggtct agttggttta taataatttt ttacgtgttc
     1561 cccagtcagc atttctaata gtaaaaagag aatacaattt caagggctgt aggacaaaca
     1621 aatgcagcac cccataaaac ggagataaca agaaggacag cgggtgctta agcatgtaat
     1681 gaatgttccg acaaagagca acaatgaaga taatcaccag aaaggctaaa accctgagcc
     1741 aatcaaattc tctgacattg cctacaaaga aatccaccac agaataaaca agcatcataa
     1801 acatagacac ctcaagtatg gtccataggg ctacaaaagg attgttcatg attttcttaa
     1861 cagaaataat ggactctcta aagaaggact tgttccagcg gttttgctgc ttcaagtaag
     1921 tagacatctt gtcaggaaca tctgtaatac atttagcagt ggattgataa acagtctttc
     1981 ctaaatcagt tgcatagttg gtcaagcacc tgtcatcacc gatacttaca ggaataccca
     2041 ggaaggtctg gttgatgtat ctgtctatat taggaacaac cacctcgcgt ctgtaaacgc
     2101 taagtgggcc tgagcaaaca aggatattac ccgtaactga ttgggcagct cgttcaacgc
     2161 caaaagcatt atcatagcga atatctgtca agcgtgttaa gagattggtt tgtctatttc
     2221 tgacattaag gtgacccgtc gcagcaaaaa cagttgggtc attaaaggtc tttaacagct
     2281 cctctaaagc atcagggtag atataagtat ctgagtcaac ggtcaaaaag acatcagcgt
     2341 ctgatctttc aaaggcccag gcctgtgcat gacgctttcc ttgatttttc tctgaccgat
     2401 gaacaatgac attgcttgat aggtcaccag tgtcacgcac atagtcttca atgcgcttaa
     2461 tacctgtctc atcagcactt ccatcgtcaa caacataaat ttctgctagg ggataggttt
     2521 gctgctgaac actttttaag gtctctagca atgactcagc gtcttcgtta taagagggaa
     2581 taatggctgc aaccttatat tgcccagccc ttcccttaaa tggcttgtaa aaaaaagata
     2641 aggacatttt gactaataga taagctatca gcaaaaagcc ataaattgac aagcttcctt
     2701 tagcaccaaa gagataaaca ttgacgtaaa tcaacagtac ccaaaaaata ctaaaggcca
     2761 caacagttat gaggtttttt aatgttctca ttgtgattgg tttgatcctc tcttgcgctt
     2821 tgtattttgc ctttaaacgc taaccataat ataccatctg tcacagcaag caaacaaggt
     2881 cattaattta ccattctatt aaagatagat taatcttagt gtcaatacag ctttttctaa
     2941 gatttgccta tgctcaccaa gtcatcaatc ccctacaaaa aacaaatgat agcctgagtc
     3001 tacctgtggc tatcgctagc atgtgcctga taacaagcag ctaaatggcc cgtccaaaac
     3061 taaggcgctt tggacagccg cttttcgctc tcttttttga catcaaaaaa gcagccctta
     3121 tcaggccact tcatattggt aacaaagcaa ttctataagg agctccttaa aggataaggg
     3181 caagagatta ctttagagac ttgatgatct caatgcgagt gataaccccc tcatgcatat
     3241 gatctactct taaggcaaca tcagaaaaag caatagatgc cccaatcgtt gcagtctttc
     3301 cttcctcttc caaatggcgc agcattaaat cacgcattag ctcgtttttg ttaataaccg
     3361 gcagctcgac acgcgctagc acattagcta ttttgacctt ttgactgccc cgaacgataa
     3421 tgcttgaagt atcatcaaag cttgtaaaaa ggtattttcg cgtcgcaaat aaaatagcaa
     3481 gagctatgac actcaacaaa gaatccttag cagagccatg agcgacaaca atttgccggg
     3541 caatcgcaaa caaaagcacc tcaataatgg ttcctgaggt atgcttactc agcattttaa
     3601 tcagctcgac accaatagca atactcatgg cctggtttaa aaagctctgt aaataggtat
     3661 caatgccact ttttatggta aaaatacctg tcaagctcaa ggccaagcgc cctgtcagca
     3721 ctagtaacga aatcaccaag atgatggaaa taataatctc aacataatga gatagctcat
     3781 acaatctaat ctgcaaatat tttctcatag caactcctta tcattattat ataaaaaatg
     3841 ccactatttg aaaataaaaa aagagcacac acccgatatc gcttagggct gctggattcc
     3901 tcccctgacc cacttcacgc acaagtgttg ctccaccttt attgtagcat atattgtacc
     3961 ctaaaacaag tcttatttca aaaacgtctc acatctggct cataaagctt aattagctca
     4021 acagcaaacc aagcaaacgc tatcaataag gccagtcctt aaagctaagc ccgactagac
     4081 ttgtgctata atggtactaa caaacctgag tggagatgat atgaaaaaca agcttagcct
     4141 attcttgctg gcagcactta ctatagtcgg tctctcagcc tgtgcatgga gatccaatcc
     4201 tcttgctgac aaggagcagc agttcggcct gactggagca agacgtcagc aggtgcttga
     4261 tcagatcgat caacgttatt attaccagca gcttagtcag gcagaaaagg aaaattacct
     4321 tctcttgtat gatagcctct cagcctttca cgaggtgact agcctagcac cagcttctaa
     4381 gcatagcttg atgacaacca ttgatgcctt tatgatggat aatcctgcct ttttctggat
     4441 tacctcagcc aactaccgct tggaacgctc ggatcaggtg gccttcgtta cctttccatt
     4501 gccagagaag gtcgaacaaa catatcacag gcttcaagcc attggagatg atatcatcgc
     4561 tgacatgcca gcaaccaatg actatgagcg cgtgaggtat ttttatgagt ggatcatcaa
     4621 gcaaactgac tacaatagag atgcctttga ggcatatcaa tcgggtcatg aggccttgat
     4681 agcctctaat caagacattc gcagtgtctt tcttgatcat ctttctgtct gcaacggcta
     4741 tgcacaggcc tttcagtttc tttgccaaaa ggccggtatt cctgtcgcct atattcgagg
     4801 gtcagtcacc tttgatcgat cacaggacgt ttttactcat gcttggaata ctgttcagat
     4861 tgcaggcaag aactatgctg ttgacacaac ctttggagat cccgtctttg atcaaaacga
     4921 atccattaaa caactagagg ttaattataa ctttttatgc ttgccagacc agctcatgaa
     4981 gcagtcgcat caagccagca gggatattgt gatcaatcag acagaaacct tgaccgatgt
     5041 ctggacaatt cctgagtgct cagacgattc tctgctctat actaagctca atcacagcta
     5101 ctttactgcc tttgatagac cagacattct ggccagtctt gagcagcaat taaggactaa
     5161 tcagccacag accagcttac aatttgctaa tcaggacctc tacaaccaaa tggtaagtga
     5221 tcttgagcag cattctgaca gctaccatag cctgtttcaa gcttattggc ctaatgctgc
     5281 tggctatttc tacagtctac accccagcac ctttagcatt agcattagca ttatcaatca
     5341 gcaatagcct aataccctga cagacaagta caagcgctta tggcatggct ctaccagcca
     5401 ttaaagagct gtgctaggct ctcaagggtc ttttttcttg ctaatcgctc aatgggctaa
     5461 atcttacttt ccttatcctg ctttttctgg tcacgccttt gccggaaaaa ggtctgcatg
     5521 agcttggcac agtcatcagc caaaagacct acctcaagct gtacacgatg gttcaggcgc
     5581 tcatcggtta agatctgata aagactacca gcaccgccaa acttttgatt gctggcccca
     5641 tagaccacat gaggaattcg agctagccca atggctccgc tgcacatgac acaaggctca
     5701 atcgtcacaa aaagagtcgt atccaagaga cgccaattgc cttcgtgcgc attggcttca
     5761 ttaatggcca tgatctcagc atgcataatc gcctgattgc gctcctcgcg agcattgtga
     5821 ccacgcccga taatgtgacc agccttcaca ataacgcagc caatcggtat ctcgtccttt
     5881 agcagcgatt tctcagcctc cttgagggct tctcgcataa aatactcttg ctcttgtttg
     5941 gaatagctca ttgagataga ctccccaaat cccaagcccg atgtggcaga gcaagatcaa
     6001 caggaatctg accagcatag ccttgagctt gctgtcgcag cacctccaaa tgcctcttag
     6061 gatcaatccc ctctggcggc agaggtggca tatgggtcaa gaccaagcgt ttcaccttag
     6121 cacggctggc aagctgccca gcctcttttg aggtcaaatg cgccatatga tgttcattgc
     6181 cttcataaag gtacacatct gctaaaaaca catcagcctc cgcagcaaaa tcagccagct
     6241 cttcaaagta gcctgtgtct cctgtaaaga caagcacctg cccagttgct ctttccacaa
     6301 tacgaaaagc atagcacacg accgggtgaa ccgtcttaat aaaggtaatg tcaaaaggtc
     6361 caagagcttc aaccctatca acctgatagg caatgccctt tgagacacct ggcaaggtta
     6421 gtttggcaaa ctcggcctca tcttcgtcat gaccgtaaat aggtagtagc cttggcttgc
     6481 caagatgcct tggatagagc tgataataat gacgcaaaac acccaagtct gccacatgat
     6541 ctggatgata atggctaatg ataacagcgt ctaaatccag cggattgatt tctttttcta
     6601 attcgttaag agaacgacta ccagcatcca tcaataattg aaaaccatca tgccctgtca
     6661 caagataggc tgtcgtccca gcatcttgat agggataggc tccccaagag ccaagcgttg
     6721 ttaatttcat cacaaaacct tccttcatgc tttgttctta ttataacaaa aaatagcagc
     6781 aaaaaataag tcctagtgcg caagagctag gacttacagg cttagtattt agctgttggt
     6841 gtttaaaaag ctgtctttat agctaacagc aagcgccgtt gcgatgactg ccttaatagt
     6901 atctcccggg ataaagacaa ggctagcaac gagcgatcta gtgagcggca tgtctgtata
     6961 aaccgctagc caaatagtcc ccaacagatc caccagcagg acaccagaaa taaagattgc
     7021 taaaaaagca agagaccgat accttgctag ccagctgcgg tacaagaatg caaaaaccaa
     7081 tggaacaaag agccaggcca aaacatagcc agccgatggt cccattagga ctggaacagt
     7141 tgttctagag cctgaaaata ctggcaagaa cagaccaatc actagaaaaa gcaggataga
     7201 cagggttcct tttttcccac ctaaaatcaa gccagcaagc atgaccccta agttttgcaa
     7261 aacaatcggc actggaacaa agcctagagg aatcgctgga ataagaccta aaataatgat
     7321 taaggtggtc atcattgcta ccttcactaa gtccttggtt gacaacatat ctcataactc
     7381 ctttgaaaaa taaatatcct gatgcttatg ataggctggg ttaaaagggc taaaacaaaa
     7441 aggacagctg ccgcactcat attcggacct tctcagcagt tgtcggcaat gaccacaaat
     7501 caccggatag gtctccttgt ggtctgtcgg ctcaaaagca tgatcttgaa gcgtgtcatg
     7561 acaatgataa caggcataat aagcctgaca tcgagcacac ttcaagccga caatatccag
     7621 cactgtgtga taatgtacac agcgatactc ctgatcaagc gcgataccaa aacagttcct
     7681 catgtcttat cctcttatta aaaggataaa gcattcgttt tattttgtca acctatattt
     7741 actaataggg ttactaatcg cataagaaga acaccaaaaa agcataaagt agtcccatag
     7801 gcagctgctt tttaccagta ccacacaaat agctatatga ctataaaggt tggcttaaga
     7861 aggttcagat ttaaccgagt gtgggaaaaa gattaccaat ctagctgcca aaatacgggg
     7921 tctcgtttga ctatttttcc ctattgggat ataatgagaa cagaaaaagg gcagttgctc
     7981 taaacaacta ccctatgcag aaccgtttaa gacggtggca tatctttaat tattaaaaaa
     8041 taatcgtcga cctaccaaag ttcagacggt tattttttat tgtttaatat gacgattgca
     8101 acgactaagc tgattaaggt aagtaagaaa ctaccaaaag ccagcatgag ttgaagggcc
     8161 tcgtaagtag acaataaaac gctcctttct gttggatttt gatgcattgc ccataggtat
     8221 caccaccttt cagaaatcag agccaccgcc ttagcttttc tgtaaagaac attattatat
     8281 cataatcaca caagaatccg tcaaatctta aactaatcag gcggcttttt tatgctctga
     8341 ctataggtct gaagagaaga tgctagatgt cttaggtggc tttccattta aactacgagg
     8401 tcttctttct cacagagtat agccccctct tttttcagct actgtttcgg aggcaagctg
     8461 gcatttcgtc taaattgctt ttgtttttcc ctgagcattc gaaaaaatcc tttatttcta
     8521 cctgacatat cactaaaaga gggtcctgtg accctctttt atagctatct gttagagaga
     8581 tatgcaattg ttagtcttgt tttttcttca agcctaggac acctgcgcta gcaatgacgc
     8641 tgagagctgc aagggtgaaa aatgggtgat ttgcctcccc cgtagctggt agcgtgccct
     8701 tttgagctgc tggagccgct gatttgtttg gtgctgactg aggagctggt gcctttggac
     8761 tagctggctg ctctgaagat tttggtgcct gtggagcagg ggattgctcc ggtgcctttg
     8821 gagtctctgg ttcttttggt gcttgtggtt gctctttttt ctccggtgtt tctggagcct
     8881 ttggcacttc tggcaccttt tgtgattccc cttgttgacc tggcactcct tgtggcccag
     8941 tatcaccttt tggaccttgt tgacctggtg cgccttgtgg gccggtgtcg ccttttggtc
     9001 cttgttgacc tggtgcgcct tgtgggccgg tatcaccctt tggtccttga agtccctgtt
     9061 cgccttgtgg cccagtgtcg ccttttggtc ctggttgacc tggctctcct tgcgggccag
     9121 tatcaccttt tggcccttgt tgacctggtg caccttgtgg gccggtatca ccctttggtc
     9181 cttgaagtcc ctgttcgcct tgtggcccag tatcaccttt tggcccttgt tggcctggcg
     9241 ctccttgagg accggtgtcg ccttttggtc ctgggagacc tggttcacct tgtgggccga
     9301 tgtcaccctt tggaccttgt tgacctggct ctccttgtgg cccagtatca ccttttggcc
     9361 cttgttggcc tggttttcct tctggtccct gtgggcctat tggtccacgc tcaccaactg
     9421 gtccgcgttc ccctcgaagg ccttgaggtc ctgcgggacc cattggacct tgaggtcctg
     9481 gtatccctaa tgaatctttc tcatacaatt tgtataattg ctctgattgg cctgtcgatt
     9541 tttttaaaaa ttgctccact cgccatagat atcttaaaac attttctagc attcgaccat
     9601 tgttataatg tgtcgaagtt tcccagtcac ttgagctacc agaaccagga ttaagtattt
     9661 ctttttttat gaactgttga aagaaatatc cttgattata catagaagga tatgtaaagt
     9721 cttctgccct tacatcattt ccaatcccta agctagctat ggttgctagg gcgacaactg
     9781 ctgagcagat accgtacttc tgaacaagcc tgatacttgt tttcttgttt ctcatgttta
     9841 tctcctttta gtttagaaat gttaacgatt tctaatcttt tttcttccaa agaaaatctt
     9901 aacatgacgc ttgcgggctg tgaatatgtt ttggggaatt cgcttccgta gtttcgtttt
     9961 tttctaatca aagggtcaat tgtctgacgc tagtgtcttt tggcattggc ctttagctta
    10021 ggaagactgc ctatgttagc aagcttttca ttagcttatc cgttttgata aagggtaagc
    10081 gacgaggata atctgacttt gtcttttgct tttgttagat tttttaatgt ttttttgatg
    10141 tctgatgact tttaaaaaaa gccttctttt gataggcaag cttaaaaggc ctaggcaaaa
    10201 gcccagaccc ttgctgctat tatctgttat tgtggaaagc taccgctctt tggcactgtc
    10261 atgcttaaaa attgcgactt gagctattgt aaccatagcg ctcaaggaaa tcctgacgaa
    10321 actctaaaag gttatcgtcc aagatagctt gacgcacctg cttcatgagg tttactaaga
    10381 agtataggtt atggtaactg gtcaagcgca tgccaaaggt ctcatcagcc tttaagagat
    10441 gacgcaggta agcacgtgtg taatgctgac aggtgtagca gtcacaatga tggtcaagtg
    10501 gggtaaagtc ctctgcaaac ttagcatttt tcacaacgag acggccctcg ctggtcatgc
    10561 aggtgccatt gcgagcgata cgggttggca ggacgcagtc aaacatgtca accccacgaa
    10621 tcaccccatc aatcaggcta tcaggtgcac ctacccccat caggtagcgt ggcttatttt
    10681 caggtaaaag tggcgttgta aaatcaagga cagcattcat ctcagcatgg ctctcaccaa
    10741 ctgccaagcc accgatagaa tagcccggaa aatccatgct cacaaggtcc gcagcagatt
    10801 gacgacgcag gtcctcaaag ccagctccct gcacgatacc aaagaggcct tgatcatgag
    10861 gacggcggtg agccttcaag ccacgctctg cccaacgact ggtgcgctca atggattttt
    10921 tcacataatc atagggctgg taaaattgcg ggcactcatc aaagctcatc ataatgtcag
    10981 accctaggtt attttgaatg gagatcgctt tctctggtga taaaaacatc tttgagccat
    11041 tcaggtgatt tttaaaggtc accccctcct cagtgatgtt tctggagtct gccaaggaat
    11101 aaacctgaaa gccgcctgag tctgtcagaa ttgcctgatc ccagttcata aatttgtgaa
    11161 ggccgcctgc acgcgcaatc agctcatctc ctggtcgtag ccataggtga taggtatttg
    11221 acaaaataat gcctgaccca atctccttga gctcctcagg agactgtgtc ttaaccgtcg
    11281 cctgtgtccc taccggcata aacatgggcg tcggaaaggt cccatgcggg gtaataatct
    11341 caccgagacg agcacctgta tgcttttcct ttttgatcaa acgataagta atagggtaat
    11401 tagtcattgt ttcttttttc cttgctatca agataaacag tcttgagcgt tttgcatacc
    11461 acttacaaag cacttagtca agcggtatgg gcttgtttag agccctatca ttttatcaaa
    11521 aaatctctga cttgtcatgc cttcaaagag acaagatccc gaagcaatgg cacgacagac
    11581 gcatgaagga gttttagcaa gaaaagaaag ctttctgtcg ttcaatgttc agctatttca
    11641 agtatatgtc ttatctttta taaactttac tacagaaaaa tcgttgaaaa tgtttgcttt
    11701 actctatact atcattcaga aatagctgtt tcgcgcgttt gtcgtgagca aggacggtat
    11761 gggtatcact ggctcctaga atatggtata atgtaccaaa ggagttgtac gatgtcaatt
    11821 agagaaataa aacgtgaagc tagacagact ttaaagggac taaaggggaa atacctctta
    11881 tttttagtac cgataatctt atctattttt tactcaggaa ttgaggttca tcagacctat
    11941 gtgaccactc aggggattga ggtatcagtc ggggcaagct actttccttt gattgttctg
    12001 ataatgctga cggtctttac cttatcagca gcctatacca tgctagatgt tatccgctac
    12061 tatcgtcgtg aggtctcttt ttcagaggca acgatagctt tttctggaaa cttgtttggc
    12121 aaggtccttg ttttgttgat catcaaaggg ctcctattta tcctatggtc tttgatttgg
    12181 attgttggct tggttattct aacgattagc tctgcggcat tactgacaag ctacaatact
    12241 ggtgctgctg tgatgactcc aatcatcttt atggttattg gttttgtgat ttttattatc
    12301 gggcttattg tttatatgaa tcgttattgt gcttacagca tggctgagta cattctctat
    12361 gacaaggtca aggaaggcac ctatatgggt gctattacgg caatcgaaga gagcaaggac
    12421 atgatctcag gctataaagg aaagtatttt ttactacacc ttagctttat tggctggttt
    12481 atcctagtaa tcttgtcttt tggcttgatc tatatctacg tactgcctta ttacaccact
    12541 gctgatgtga ccttttacca ccatttaaag cacattcacg atgaaacaga gctgccgata
    12601 gatgctgaaa ggcttactat cacaggttca aaagaagccc catctgctat tagctagcct
    12661 taacgatatg cctctatgtc tctcatgacc ttgttcagag tagacataga ggttttttgc
    12721 atgacctttg ataacttttt tatagtaaaa aagaggagcc catcagttgc ctatccaaag
    12781 ctagatgaca catctaacgg ttggaaggct tgcttacagg ccctctttta gcaatgttag
    12841 cccaagacta tcctaaagct gctgaaaagc tcctcggtct aaggcatagg cagtcgtcca
    12901 atggctctca cgatagtaaa taaagagctg gctatctaat agctcatcaa ttgaggctgc
    12961 tgttggcaga cctgctaggt caatgaaata atcccctgga agaagctgtt gtagcttttc
    13021 cattaaggcg gtattaacag cggtctttgc tgctggtaat tgactagaga ttgataagcc
    13081 ttcaaaggtc tttaaatcta tgttttctga ctctaaagct gattttaagg ctgatttgat
    13141 caagtctagg ctgtattcag catctaaggc ttcatcgcct gatgagaggc tattcatcgc
    13201 caatacatac aaagggcctg ctgccttatc ctgataggta atgacaagtt gatggttcag
    13261 caaatcagct aagtcatcat aagtaccagt gttctcaaga gtaatgtaat aagtccctgt
    13321 gagccctaag tccttgattg tctctaaaat cttgccttgg attgcttgat ttttttcagt
    13381 tgttgccgct gttagaccac tatttgtaat agcaaagctc tcaatctctt tggtagctgt
    13441 attggtctct tttagaatgg ttagaatact atctttaagc gctagaatat catttctaac
    13501 cggtgcttca atagggctag agatgtcttc aaagaaacga taagcagaac cgctgacaaa
    13561 tttattggcc tgtccgctgc tttttccata ggtgtctaag gcagttattc taacaaatcg
    13621 acctgttgtt ggtgtaaagc tgactgtttt tagctcagta ttttgcttcc aatcagtgct
    13681 atcgacaacc gttgtccaga ccttaccgtc tgagctgatg tcgacctttg cagaatggat
    13741 cataccatta acacctcctg ggagataggc aatagcagag aagtttttat cgtccttaaa
    13801 ctcaacagta tatgacttgt cctcagtaac ctgattaaat aaggtatgcc attgggtggc
    13861 catatctcta ccatctacca tatgcttgcc agacctgcct gattgctcat tagcataggt
    13921 caccgcctga atatcatcaa ttgagatgta gtgcattgta ggatcagtgc tgtctgcggt
    13981 aaaggtatag gtaacgctgt cacttgctag actggtgcca tgagcccgat agcgagcaag
    14041 aactgtgaca gtgtcattga agcgctctgt gccatcataa gcctgccaag actggccatt
    14101 atccagactg acctccaaat gttcaatagc accaatcaag cgattttcca agtcattgcc
    14161 ataaaggctg ctgttggtcg gtgctgctgc ctttgtcagg ttaatcctgt aggtagcaga
    14221 taccgcgtca aagccaacta aaataccgtc ctctatatta agcttggcca aaaggtcatc
    14281 actaaaaacg ataaccttgt ccttggtttc aagccatgtt ttcccattat caatagaata
    14341 gcggactgtc aaatctgtat cctgataatt ctcatgcaaa cgaagggtct tgtcatcaaa
    14401 gctaaagctt gctgtttcga ttggattgcc cgttaggata tagttggcga taattctaac
    14461 ctcattagat tggagcactt ccttatcagt tgctgttttg gctgcgatta gagcgttata
    14521 gctcagtaaa tctagctcag ccttagctgc ttgatcgctg atattaggcg tgatacgctt
    14581 gatagcctct accatgacct gtggatagta ggtgtaagct gcaatgacac gctttcctaa
    14641 gtccagccaa tcctgatctg ttttttggcc attttttgca taggcctcta tcaagccatc
    14701 gtaagtatct agattaagct ctagtacatc taaagccttg ctgtaggcct caatctgttg
    14761 atcactgcca gcctcgtaga cattagcgat gagattataa taaagcgatt ccttgaactt
    14821 atcgtattgg tttaaggctg cttgcgccag cagcatatag ctagcgtttt tatgaatgtc
    14881 attgtaggat tttaggcccc agccaagcaa gagcctagcc tctgttgctg ttgtggttcc
    14941 ccaacgagaa taagagattg cccagcgatt accataaaca ttgtctctaa tatcccaaat
    15001 cccgttgccc tgatcatctt gacggtaaac caaataagcc tcgtggtcat tttggtaaat
    15061 attgaccgct ggaataccaa agacctcatt gactgctaca cctaaatttg ataatcccca
    15121 gcaaacagcc cctttttcca tcagcatcca gatccggtga cggttgtcat aagtaacatt
    15181 aaaggcatcg tcattgaggg tgccaacgag ctgatatttt tctgtccatt gagcttgatt
    15241 gtcagcgctg cgcatgtctg cgccaccgta gccgatgttt ttgtatttcg tataagagta
    15301 gccactggta tagctagcaa ccttatctcc atatttttgt tcggcgtaat gatgcagcca
    15361 gagaatttcc tcatcatcta ttttggcgtc cataacagca cgcaccaact ccatattgta
    15421 gttggcgaat tcttctttcc tcaagaattc gttgtctcga tacaattctt taaaggcttg
    15481 atatttcagc accgggtcag aagcaaggta ggtgccacca tagttaacca caaaggattt
    15541 gatctccttg cagtaggcaa cagcagttgc cagcatcatt tttttgtaga catagccatt
    15601 tcccttgtcc tccaaatctg ccttattagt agcataaagg tctcctaagg cgttcaaggt
    15661 ttttagggta gagccgttaa acatcgagcc tgcctctaaa aacagtgaca gagcgtcctc
    15721 atctgacaat agccaatcaa gagcgacctt gaccttttca tttttcttga cagcagattg
    15781 aatggtgtgg tagccgacac gattgacaaa ttcgcgctca agcactaatg ccaaattgtc
    15841 tggattatca taattatctg tgacactatt cttgctgaga agggcatcat actcttcagt
    15901 tgtctttagc ctgtcataag acacctcgct tgataaatca taatctgtct tgagcaacct
    15961 gagatccgca taaacagagt gatcattacc gttatttttt agtgaatttg caattagctt
    16021 tacatattta gcacctgtaa tatctagatc aacataaaca gcctcactgg ttccggttac
    16081 tgtaccagtt gtcaccaggc tttcccaact ttttccgtcc ttagacttat agatgttaaa
    16141 gctaacacca tcgtccttac cacgtctact atagtcaact cctaggtagg ctgatagacg
    16201 cgtgtattca ttggagtatt gttcaacatc ataataaagc tgtgaaggag catgcactgc
    16261 aattccctta tcaaatgcaa gcacctcgcc atcaactact agagtaatgg tgccaccggc
    16321 agggtttttg tcctgtaaaa agctgccatg cccaaccttg gacgggttga cacgtgtctc
    16381 atctgataag tagatatagt ccttagcttc agtcttattg gtggtctcta ctgcttgtga
    16441 tacttctgtc tgctcctgct ttgtggtctc ttcggcagaa gcttcggtag cttgctctgc
    16501 tgcggctact tgactcttag agtcagttgt ttctgtagtg gcagtaccta ttactactgg
    16561 cagcgtttct gaggagccct cagctgctgt gtcttgcgca gcggttgctg attggtcagc
    16621 tgcttgttga tcaaccgctt cttgtgcttc taacgtggtt gctatggctg cactagctgt
    16681 tacttgctgc tcatcagcag aaacagttgt cagccctagt gttaaaaata aggttgcaac
    16741 caacacagag gctgcacctg ttttaaaggt tttaatggca aagcgctgct taccatcagt
    16801 ataaggtttg aacatggtgt cttctccttt aaaaataaga tatttaagca aaataaagac
    16861 tgaccaccaa ccactacagt tgataatcag tccaacaaag atatcgtact ataggaaatt
    16921 aattaaaggg ggaaaatcat cgcctacagt taatttgatt ctttgcgtct tgacacaata
    16981 gcaagctggc ctgcacaagc aataactgca agagctgctg ctgtaaagaa tggattagct
    17041 gtatcagcag ttgccggaag cacttgctgc ttatcagctg ctttcttgtc ctccttctta
    17101 gcttcaggct tagattctgg tttaggctct ggcttaacct caggatctga tggttttact
    17161 ggatccgctg ggtcgattgg atcgaccggg tctaccggat ccactgggtc taccggatcc
    17221 actgggtcta ctgggtctac tggatccact gggtctaccg gatccactgg gtctaccgga
    17281 tctactgggt ctaccggatc cactgggtct actggatcta ctggatcgac cggtttagca
    17341 accaaggctg ccttggcatc tgagagggat ttcttagcat ttaacacctt aaccaagctg
    17401 ttagtaatag ctgtcggttc tgtctcctga gcataagctg tctcacccgc tgctgcgacc
    17461 tccttagcct tagctagctg gtctgtatag gcttgagcag aagctgctgt atatggagat
    17521 aggtctagat tttctccgat aagagcattt aattggtcta aagcagaacg caattttgcc
    17581 tttccttctt cggcaatcgc agcctttacc tttaaaatag tatcaacaac tgaatttgtt
    17641 tctgtagtgt agcgctctag ctcataaagg gaaatgtctt ttctctcttt atccttgtta
    17701 acagttctat agaaggtacc tgctgcttca atggccttat tgtacaattc cttcaaagac
    17761 tctgatgtca aagcaagatt tggattttct cggtaaagct ctaacagctt agccaaggct
    17821 tgatctaagg cttcatgcgc tacagcagtc ttaagcgtcg taagagcttg cgttaaatca
    17881 gtcgcagcct tatcaacatc tccttgtgaa ggaccaaatg aattttgaag cttagctgcc
    17941 gctgcaagct tttgcacaag accgtcatac gcttctttag gatactcttt gccatctgtt
    18001 ataaaaggtg tagcttgatt aatagcttca tttaaagcat taagattaac aagactagta
    18061 atagcggaat caatagtagt aacagattga tctactgtat tttgatcagg gtcactgttt
    18121 aaataggtct taccaatagt aaccgctgat tgcaaggctt gcagtgattc atcagaatac
    18181 gttccttcag gctggctgag ttttagctta gcctcctcta acgacttcct taactcagtt
    18241 ttattgctgt tggaattttt tagtttaaat gtgaagagct ttttggtatc atttttccca
    18301 tagaataccc aagctttaat agtataagat ccccccggta cagcatatgt aggcgaagct
    18361 aacatttcat cagttaaaaa ggaagtaccc gcagcattgt aaaagtcaaa ccatattttt
    18421 actccagggg tatcaattcc tcttgaacca tctccattcg aaataaagtc aaaagtatct
    18481 ccatcattaa cagtcccatt actaccttta cgagtaaccg taatttgact cataagatct
    18541 gagatagtaa ttggttctcc taattcaact gtatattctt gtggaatatc tatgtgccag
    18601 ttcagatgtt gacctgtccc attattttca aatgcactag cagtagtcgt ttccgcccct
    18661 actgttaaag cgctatcaat attatccgac aaggcaacca atcctgtgct gaaaactaat
    18721 ccaacaagac cacagccctt aagacaccgt ttcgtgaatt tcttcattct tctttttcct
    18781 tttctagagc cctagcaggc tcgaacaata gcaatatgtg tcatagggca gctgctatca
    18841 ctagtagctg ccactttgat attagcctga ttgtgacact caaatatcac ttataattta
    18901 caaaaaattt taagaaaagt caatatacaa acggtttttg ttaaattttt taaaaatata
    18961 acaaaaaaca agcacgccaa tctggtctat aacagttttt attgtcaata gtgatcgcta
    19021 aagggttttt cagccaacaa aaaaagagtg aatccctaac tctctcttct agactttgtg
    19081 ccatatcatc agctacacga acagccaaga tcaaaaaggc cagctctcaa tagtctgtgt
    19141 ccttaccctg cttcgtctga cagctagggc aaacaccata ggctataact ggaatacggg
    19201 tgaccttata gcctgtttgc tggtgtgctt ccttagcgat atccatcaca tctacgtcca
    19261 taaaatcagc gattgtcccg caaacctcac aaaccacatt gacatgctga tgtcccataa
    19321 agtcataata ggtcgtcaaa tcattactaa ttttcagctc ggatacaaag ccctcatcaa
    19381 cgagaacctt caaattatta tacaccgtag caaggctcat attagggtat tgaggctgta
    19441 aatcacgata gattttatct gcgctggggt gctcagtgga ctgaatcatg taagaaatga
    19501 tcgccttacg cgtctcggta atacgaatat gcttgtcacg tagatgctct aggacatttt
    19561 cataggcatt tagagcttgc tgatgtgaat gaatgtccaa gcttacaacc tcctcctttt
    19621 gtaactatgg cactaactag caggaatctt gatcctgctt gctgattagc cgtaaatagt
    19681 caatcttgat acagcgattc ataacaatgt cagctttgcc tgctgatcgc aaaagctcct
    19741 cagcttcttg gctatacaag ccaagctgtg cccaaaagac ctgaccctga caagctaaaa
    19801 agtcctgagc aacctgaggc aaatactcac ttcgtcgaaa gacattggca atatctacct
    19861 taaaaggaat agccgcaagg ctagcataaa cgacctctcc taaaacagac tgacctgcca
    19921 gcctaggatt gacagggaca atccgatagc ccttagcctg cataaaccta gccacatcat
    19981 aagcagcagt ggtttgacga tcagataagc caaccactgc aatggtcttg gaagattcaa
    20041 gataagaggt gatagtctca tcagagggat tttgaaatgt atcaatcatc atttacttcc
    20101 tttttatcaa gcacacccaa tagcaaatca acaacaggaa aagacaatcg ctgccggtat
    20161 gacatagcca accatctggc taccaagctc aaggaaaacc ctccttagca tgacatgccc
    20221 tgctgttttt ttctcttcat tatagcataa gtttttaaaa tgcggaacac aaggaataac
    20281 agcagccaca ccaagcaggc tgccacttaa caccactgct aatctagtct acttggcctc
    20341 ataccagctc ttgccggcac tttcgtctac acgcagcgga actgccaggc tgacagctga
    20401 ttccatcgtt tctttgacca gcgctttaac agccgctagc tcatgattag gcacctcaag
    20461 cacaatctca tcatgcacct gaagcagcat tttggtctca aagccaccag ctactagggc
    20521 ttggtcaaga tttatcatcg caattttgag aatatcggct gcactgcctt gaatgggcga
    20581 attaatggct gtacgctctg caaaggagcg aacgttgaac tgacgagaat tgatatctgg
    20641 caattgacga cggcgcttaa agagcgtctc aacatagccc ttatccttgg cttcacgcac
    20701 aaccctttcc atgtaagcct tgataccagg gtagcgctca aagtaggtgt caatataagc
    20761 cttggcctgt tttcttggaa ttccaaggtt attagacaag ccaaagtcag aaatcccata
    20821 cacaatgcca aagttaacag ccttagcatt ccgacgatca ttggcagtga cgtcctctgg
    20881 cttttcaatg ccaaagacac gcattgccgt tgaggtatgg atatccgctc cctccttaaa
    20941 agcagcaatc aaatgctcat ctcctgaaat atgtgctaaa acacgcaatt caatttgcga
    21001 ataatccgag ctaagcaaaa cagcatcatc atgagatgga gtaaaggcct tacgaatcaa
    21061 gcgcccctgc tccagacgaa tcgggatatt ttgcaggtta ggatcaacac tggaaagtcg
    21121 gcctgtctgg gttaaatcct gtaaatagcg ggtgtggatc ctgccatcag ccatgatgta
    21181 atcctgcagt ccaatcacat aggttgattg cagcttagta atttgacgat agtccaagat
    21241 cttagccacg attggcgcaa ttggcgctaa gcgctccaag acatcaacag ccgttgaata
    21301 gcctgtcttg gttttctttg tcaaatgaag agggagctgc attttctcaa agagtatcac
    21361 tcctagctgc ttgggagaat taatattaaa gacctcacca gccatttcat agatttcctg
    21421 tgtcagttcc tcaatgacca ccttattttg ctctgccatt tcctgcaggc tatcttgatt
    21481 gacagcaatg ccttcgattt ccattttcgc aaggacattg gcaagcggca gttcaatgtc
    21541 agtgtagaga tcagcctgct catgctctgc cagcttatca agcatgactg gtctactatc
    21601 cagcaagacc tgaaccttac gcgccagatg tcctaacaaa acagccttgt caggcacagc
    21661 acgcttgacc cccttaccat agacaacctc atctgtatcc agtgatatag tggtataaag
    21721 acgtgccaga gtagccatct cattgtcctc tacagttgac aagaggtaat tagctaagcg
    21781 ggcatcatag ctggcagccg gcaaatcaag ccccagatga ctaagcagaa ccttactgcg
    21841 cttaaaatca taggtagcaa tcggctgctc aagaaccttt ttaaagagct ttgtagtgag
    21901 gagactaata tctgctgaag cataaatctg gccttggttg ccccaagcaa agccaatcag
    21961 ctcctcgcgg tgataattat ccctcaaagc ttcaaaataa aacaccgtat cgtctgaaaa
    22021 catgtccgct cttatgtcag taacttcctg ataagcaatc tcagctaccg gctcctgtgg
    22081 caactgacta gctaaggcat tttttagttg aacaaaatcc atctcatcat aaaattgtga
    22141 caagcgatct agatctggac cctgatagac aatatcctcc aatccaatcg taatcggagc
    22201 gctagtgttg atagtagcaa gtgtctttga gaggaaggcc tgctccttat catgaagcag
    22261 gttttccttc atttttgaag gcttgaagct atcaatatgc tcgtaaatcc cctccaagct
    22321 tccatattcg tgcaggagct ttagacctgt tttttcccca attttggtca ctcctggaat
    22381 attatcagac ttgtctccca tgagcgcttt caagtcaatg aattgctctg gcgtaagccc
    22441 cattttgtcc ataaggtagg ctggggtaaa ctcttcaaat tcagcaactc cttttttaga
    22501 aatctcaaca acggtatttg catctgtcag ctgaatcaaa tccttgtcac cactgacaat
    22561 agtcacatca aaaggaatct ctgtacgctc tgccatttta tcaagcgttc cgataatatc
    22621 gtctgcctcg taatgctcta gctcataaaa ggcaatacca agcgctccca gcatatcacg
    22681 aatataagga aactgctccc gaaattcatc aggggtcttg gcacgtcctg ccttgtaatc
    22741 agcaaaaagc tctgtccgaa aggttgtttt acccgcgtca aaggccacca agacatgcgt
    22801 cggctgaaca cgcttcatca tgtggtctag catcaaatga aagccataaa tcgcattagt
    22861 gtgaagaccg ctgtgatttt taaagcggtc aatctggtta tagagggcaa aaaaggcacg
    22921 aaaggccact gaggagccat caatcaaaag taatttattc ttgttttcca tgcctttatt
    22981 ataccacaca gtgacctgct ttgctctgac cagctacgct ttttgcaagc actagcaggt
    23041 aaagcagcat acccgtagct tgatcaaaag atccaagctg cttgaaggaa gataaatgac
    23101 tgcttttgct ttatcatcaa gacatttcta ccaaaaaaga gactgagata aaaagagtga
    23161 cactttagag agtcttaact aatatccttt gttatctaat tcattaacaa acgaacaggc
    23221 ctagttttca aaacctcaga aaactaaacc tgttcatttg ttctatttga agtcagactt
    23281 tgtctcaatc tccaaattga tgacatcatc tgctatgact ttcctaagct gatatggacg
    23341 gaaagccttc tgcaaaatcc atgattagtc taggctacat ttgagcgagc ggccttatga
    23401 ctgagtccat ttggccacct tatcagcatg gctagccacc catttcttgg ctgcggcttc
    23461 tggtgtcatg ccctgattga tgtcaagcat aacagcctcc atatcctctt tttcccaatg
    23521 gaagtgatca acaatcctat gaacagctgg caggtcggcc tttaagcccc gacgtgcaat
    23581 ggtattgata ttttcctttg agccaaaggt tttctttgga tctgccaggt atttcaaatc
    23641 gtacttagca aacatccaat gaggagacca agccgtcaca acgatcggct cctttttctt
    23701 gaccgcctga tcaagtgagg tggtcatagc acctgtcgaa gcagcaacga gctcccaatc
    23761 tgccaagttg gaataggcct tttgcgtctt atcagcagca gtcataatac cagctcccgg
    23821 ttcaatccca ataatctgtt gattggcttg atccgaaagc tcctctatgc tgttcacatc
    23881 gctcatatag gctggcacag cgagtcctag ctttgttccc ttcagattag gaccaagatt
    23941 atccagctta tcctgatact tttggtactg ctgctgatgg gtcactggta accaggcact
    24001 tgttgaaaag tctgcatcgc catttgcgat ggtttgccac atcacagcat tatccagtgg
    24061 tgtcaaggtt acctgataac cctcatctct taagacctga gcgataacat gggtagaagc
    24121 cacctcagaa tcccactgca cataagcaat ggtcaccttc tgccccttgt ctgctgagct
    24181 tgataacatc gcagcaaagc cacgccccaa agctgacaac aaaaagacag ctaaagcagc
    24241 tagaccaagc catttcttgg tttttccagt ctgcgttctt tcttgcggct taccgttaaa
    24301 atgctgagtc atacgatcca aaataatcgc caagataaca agggccaaac cactaacaaa
    24361 gccacgccca atatcagcat gctgcaaggc cgataggacc tcacgtccaa gacctggagc
    24421 accaatcatt gagcctgtca caaccattga tagggccaac atcatggtct gattaacacc
    24481 tgccatcatc gtatgctttg ccaagggtaa ttcgaccttc agtaattttt gtttaggggt
    24541 tgacccaaag gcatctgaag cttcaaccaa ttctgtcgga atatgacgaa gcgctaaatt
    24601 ggtaaaacga acagtcggcg gcaaggcaaa gataaccgac gcaaagacgc cagggaccat
    24661 accaatgcca aaaaaggcga cagccggaat caaataaaca aaggctggca tggtctgcat
    24721 aaggtccagc attggattaa tcacctggtg aacaatctta tttttagcca tccaaatgcc
    24781 caagggaata ccaagcaaga cagagatgag gcttgctacc aaaaccagcg taaaggtatt
    24841 gatcagctct gcccacaggc cttggttata gacaaataac aggcccagga gggtaaagat
    24901 cggcaaaggc catttttttc ttgccaagaa aaacatcgca caggtaacca atagcataaa
    24961 cagtaacgga ttgataaaca aaagggtctg cgtgatccaa tccatcaaag cattgcccac
    25021 aagctgcagc agatcaaaga agcctgaaaa ggtttttgtc agccactcag ttagttgctc
    25081 aaccagctgt gccactggta gagttgtttg taataggttt tccaaaatac agtctctcca
    25141 ttctaattaa ggtcgtcatc tggaatatta gccaaggctt caaggacacg cccacgaata
    25201 ataaccccta acaagcggtg ctgctcatct gtcactgcaa ttggcgcaga agagtcataa
    25261 atcaagggca aaatatccgt aataacagta tcctttgaga ccgttctgac attacgatca
    25321 ataacctctg acaaggggag ctttttctga cgtgcttcaa tcgctccgtc tgctgttagg
    25381 cttcctatta gctgacgacg acgattggtt gccatgagca tagacacctc ctcattgtgc
    25441 atacgattca aagccacctg cggaccgtcc agatcaaccg ttgttgtgat aggcttaatc
    25501 ataatatgct gagcagtcag cacctttgag cggtcaacgt cctctacaaa ttcacgaaca
    25561 aaatcattag ccggattggt tagaatatcc tcacccgtcc caatctgcat gatctgaccg
    25621 tccttcatca aggcaatacg atcaccaata cgcagagcct cattcaagtc gtgactgata
    25681 aaaataatgg tctgcttcat cgtctcctgt aattctagca gctcatcttg catgtcacga
    25741 cgaatcaagg gatctaaggc agaaaaagcc tcgtccatca gcaaaatctt agggctgttt
    25801 gccaaggcac gcgccaagcc aacacgctgc tgcatgccac cagacaattg atcagggtat
    25861 tggtccctga cctcaagaag ccctgactga tcaagcgcac gctttgcaat ctctcgacgc
    25921 tcctgctttg gtaccccacg cagctccaag ccaaactctg tgttttccaa aatcgtcttg
    25981 tgtggaaaaa gagcaaagct ttgaaaaacc atattcatat catgcctgcg aacttctctg
    26041 agctgatcca cagacagttt agaaatatcc cttccctcta ataaaataga gcctgctgag
    26101 ggctcaatta atcgattaag catacgaaca agcgttgatt tgccgctgcc tgaaaggccc
    26161 atgatcacaa aaatctcgcc ttcctgaacc tcaaagctgg catcatagac cccgacagta
    26221 actcctgtct ttttaaaaat agcgctctta cttttaccag ccttgatcat ttcaagagct
    26281 gctttttgtt ttttgccaaa caatttactc aaatgcctga cctctaaaat agttcccatt
    26341 cttttcctct cttgttctct tcctcgatta aagctaaatt agcttaatag atttctaaaa
    26401 gtgccaccac aattttaaaa taatgaggtc actttttgct taaaaaaaga gtctgcctaa
    26461 acagaacaca ttaattatat aatatatggt cactttttgt caagctggac gcttgctacc
    26521 caagtatcag gatcgtccta agcagtgata tcactagtca accaagcact taacagccct
    26581 gaacagacca cagcaagcag gcctttctga cacttagcgc cttgagagct tacccagcag
    26641 cctcctctag ctgacttgat tgacctatct gactcttgtc ctgcaaccaa accaatgctt
    26701 agactgccaa gcaagctccc aatagcaata agatctgcta agcaaagcgt tagcttgctt
    26761 tgaccatagc tgctagtcat gtctaatagc actctagata aatcaaaagc cccacctagc
    26821 aaggctagat gaggcaaaat aggtttagag aagggcttta aactgaatat ttgagtcttc
    26881 caagaagcag tcgtcaaagc cacgtgggtg atgatactcg atgcgatcct gatcctgtgg
    26941 ataggtgtat ttgccaccaa cctcccaaat gaatggatgg aattggtatt gcaagcgctc
    27001 cttacgcatc ttccaaagct ctaggatttc atcagttgag gccatgaagt ttgaccagat
    27061 atcatagtga accggaatga caaccttggc gcggagattt tctgccatac gaagtaggtc
    27121 aacagaggtc atcttatcct gaataccgat tggattttca ccataattgt tcaagacaac
    27181 atcaatatcg tagtcacgtc catgcttagc aaaatagttt gagaagtggg agtctgcacc
    27241 atgatagatg gttcctcctg gtgtttcaaa aatgtagtta acggttttgc gagctaactc
    27301 ttcgtcagtc actggaagtc ctgctagctc gccaccattt tcctcagcgc cagcaactgg
    27361 taaggtaacg atacaggtac ggtcaaagga ttcaacagca gtaaccttga tatccttgaa
    27421 tgcaaagcta tcgcctggtt ttaccacgat gatacgatcc tttggaacac cccagctctc
    27481 ccaaatcttg ccgcactcat aagggccaac aaatttgaca tggtcaagct ttggattgtt
    27541 gataatggct gctgcagtat tgatatcaat gtggtcacta tgataatgag acaccaagta
    27601 atagtctaac tcattaatca taaagggatc aataaccatt ggctgagctc ttagatttgg
    27661 ttgtagcttg cgaacccctg ccatattggc catttggtga ccacgaacca tgtcttttac
    27721 ttttttagtt gcctttccac gattggacca taggtccatg acaacattgg caccacccgg
    27781 tgttttgatc cagataccgc agttacctag ccaccacata gagaaatttc cttcaggcac
    27841 tacctcttct tcaatttctt cgtttagcca ggttccccat tctgggaagg tgctaagaat
    27901 ccatgattca cgagttatat cttgtacttt agccattatg tttcctccaa aatgaatttt
    27961 tatctatact ctaagtatag accttcttta ttctcataaa aagaccaagt gtcacacact
    28021 cttgtgttca aaactggact gaattttggc tcaaaataaa ctaaaagccc cagccttctc
    28081 ctaaaccaat agacagctga ggggtcctta tcaataggca agctagtagc ttacaataat
    28141 tcgtgatgaa tgagcttttc aatttttgtt ttcaaggcat agcggtcagc atcgtcctta
    28201 acaatggtct cgatcgcctt ttctagctca agggaaaaac gagagctatc actcaagcgc
    28261 ccctgctttg aaaaacggat caatctaata atgtcatcat cgctcaaaat aggattgaca
    28321 atcagtacgg gaacaagagc ctccagtgcg tctgttgttg ataccacaat gtcaacagac
    28381 atcaaatcaa agacactctg gtattgctct gttgtaaaga cagcctcgat ttgacaattg
    28441 ggcaaataac gctggcactg cttcaacagc agcttttgaa tcccaatgcc atcatctgaa
    28501 acgataacaa gcttggtctt gtcccagtca gcatgactat ggcgcagctc tcctcccaga
    28561 tgaatcgtta gataagccac gtcatcatct gttagacgga tctgccaagc ctgctctagg
    28621 attacagcac aggattgagc catagcaaag agctcctcgt atttttcctt aatatggtct
    28681 gttaaaggat tgatcgaaaa aatcccatag gcctttcgat aaacaagggc cttgcaatgc
    28741 ctggtcagct gtctaagcaa gtcctttttg tgggtaaaat gcagctgata gcgcagctcc
    28801 agctgatcga taaaatcacc aatagtggct cgcatctgct cataatcctg actttcaaca
    28861 tggtgatcct gatcttttct aaaggatagc atcagcatgg ctatcatgcc tacctcaatg
    28921 tcatctaaat gcagcttgaa attgtggtaa agctcactag ccaatgcctt agcaatctgg
    28981 tattccttgc gcttccaaat caggttaaaa tcccttttaa gcgctgtttt agtttccgaa
    29041 tgcaattgca tgttgcgata gctaagcagg ataaaaggaa gaatttgcag cataaactga
    29101 ctatcctgaa tattaattgt tttgcctagg ctagcctgag acaaaaagag gtattcgtga
    29161 aaataatcca aaacctcctt tgaaaaataa gctgacaagc cttgtgtctc agaaagctta
    29221 tgatcaaaaa gctcaataaa gctgctattg cctccctgat aaacacctgc caataccttg
    29281 taaaggtact gaatcaaagc catagggtga cagtcaaagt aatagccctt ggccttggtg
    29341 gcatgcagct gaatcttatt gttatagcta gacaattcct ctctcagttc agcaaggtca
    29401 tttaagatgg tatttctgga aacatcatta atcatcatga gcttatccag tgtcacccgc
    29461 tctgttgcca ctgcaatata aatcgctgat aagctcctgc gctcatcacc cttcatgaca
    29521 tagtgataat ctgccacttc attgaggagc tgttggcagg cagccttttg ctcactattt
    29581 agcaagatgc caacccgagg ataggagaca atttgagcaa catggctggg cagcgcttcg
    29641 ttaattttat ccaaatgata atagattttg cgccgcgact gacccaaggc agctgaaatc
    29701 gccatgactg tctcagcctc cttcaatcga atcagatatg acagcagatc atagcttttt
    29761 ttatccaaaa taatcacgtt catacctccc ttctataaaa catcactacc acacagcctt
    29821 atcagtttac cattttacct atctgtagga aagaatacta ggccaaagtc aatttctaaa
    29881 taggaaaaaa cgaacgatca ttagttttct gaagataaaa ttcctaatta gttcgctttt
    29941 ttcttttata attgtaatag ttgaattaat tattaaactt tgtctaaaat aagaggcttt
    30001 ttatcccaga ttgcaacaag ggttaacacc ttgaccttaa gcctagctaa gcagctctca
    30061 ctaagttact agctgctgcc ttaatgccgg ctaccttttt ggccataata ggcatttgga
    30121 ccatgctttc taaggtaatg cttgtccata atataggttg gagctggctc cacacgagga
    30181 ttgatttgtt ctgtcaggcg gttcatcttg gccacctctt cgagcaccac tgagtgataa
    30241 accgctaatt caggcgtctt gccccaagta aagggaccat gattgcgaac aacaatacca
    30301 ggcactgcca tcggatcaag accacgacta gcaaattcct ctaaaataac cgtacccgtt
    30361 tctttttcat aggctccatt aacctcatcg gcagttagag agcgagcaca tggaatgggg
    30421 ccataaaagt aatcagcatg agttgtccca taaaatggaa tatctcgccc agcctgtgcc
    30481 cagccaaccg cttctgttga gtgtgtgtgc acaatcccgc caacctctgg ccatgccttg
    30541 tataattgca catgggttgg caaatcagaa gaagggttca gctctccctc aacaatagtg
    30601 ccatctaagt ctgtaacgac catattttcc ggtgttaatt ggtcatagtc aacgccgctt
    30661 ggcttgatga cgatacgtcc cagctcacga cagacctctg agacattgcc ccaggtaaat
    30721 ttcaccagcc catgcagcgg tagggccttg ttggctgcac agacacgttc acgcatttct
    30781 tgtagccttt ttgccattag cttaaccccg ctttctcaat cagtggataa aggaaatcct
    30841 gtgcctcctt gatggcagct cttgtctcct ctacagtttc acagttttct gaccacattt
    30901 caatcaaaaa tggaccatga taatgcgttt tcttgagcac atcaaacatt gcttcccaat
    30961 caacacagcc ttgaccgaat ggcacatcac gaaattgccc tttagatgtt tctgtcacag
    31021 cataggtgtc ctttagatgc aaggcagcaa tagaccgatg cccattgtaa aattcactcc
    31081 agaggtcatt atgccaagca gagacattgc ccgtatctgg atagacaaag agataagggg
    31141 agtcaatttc tttttccaca gctaggtatt tctcaattga gttgataaaa ggatcgtcca
    31201 ttatttcaat ggctaaaata acctgagctt cctctgccca agtgcaggcc tgtctgagat
    31261 ttttgataaa gcgcgcacgc gtttcaggtg atttttcttc ataataaacg tcatagccag
    31321 ccaattgaat ggtacgcaca ccaagatcct gtgctagcac aatgcatttt ttcattagct
    31381 ctaatgatgt cgcttctgtt tctggattgc tagagccaag tggataacga cgatgaccag
    31441 agaagcaaat gcttgggata cgaacccctg tttcataaat agccttgaca atgtctagtc
    31501 gctcctgttt actccaatcc aagcgcgcta ggcgagcatc tgattcatcg acagacattt
    31561 ctacaaaatc aaagcctaat acctttgcaa attgcaagcg ttccagccaa gtaaaatgct
    31621 ttggcgttgc tttttcatat ataccaatag gacgcgccat attgttaccc ccaaatgcgt
    31681 cgaatctcgt ctttaaaggc acgtgccgct gctgcaggat cctctgcttc agtgatacca
    31741 cgacctgcaa taaaggtaaa gacattaacc ccttcaaaga gcttgagggt attgatatct
    31801 aagccacccg tcaccgatac acgaaagccc atgtcaatga gggctttgac cttgttcaga
    31861 tctttttcac cccatacttc accagcgagt agggcgtcac gtgattgatg gtaaatcgcc
    31921 tgtgaaatgc ctgcatctag ccacaattgt gcctgttcat aggtccaatc accatacagc
    31981 tcaacctgaa tctcgccacg ttccccacgc tcttctttga tggctttcag tgcggctgcc
    32041 atggttggaa tagtggcaca gcaaatacaa gtcatccagt ccgcaccacg cttagcatta
    32101 ttcttagcaa cagtaccgcc agcgtctgca cacttggtgt ctgctacgat gatcttctct
    32161 ggaaataagc tacgcagcac ctcaaccaat tcgctgccta cttgaagcag gcaaactgtc
    32221 cctgcttcga ttacatcaac ctcgtgacca actgcaacag cagccctgac cgccccctgc
    32281 aaatcagaat gatctaaggc aacctgtaat tttggaatat gtgtcatgat tttctaccaa
    32341 gagcccgtag caccgccttc aatgcttaat agcgagctcc tatcctttct gttgtgtttg
    32401 attcgtttag tgatgatggc ttgtctaaga atccaaatcc aagccctcta aataaggact
    32461 atttttggac tcgtccacca aagccaaaac ctctgctgga gtgtgacagg caactaagcg
    32521 cgaaatagcg tcttccagtt caaaaagggc gacaatctgt ggaatagcaa ctgttgtatg
    32581 aatagaagga tcagttgccg ccaaggttag caataccgaa gcctctttgc catctgaaaa
    32641 ggtcaccggc ttggtcagtg tgataagagc aaaggcattt cgcttgaccc ctacaccagc
    32701 ctctgcgtgt ggcatggcca ttcccggcat aaggacataa tagggcccgt acttttctgt
    32761 tgatgcgata atagcgtcat aatattcaga ggtcaccgcc ccgctgtcaa tcaaaggctg
    32821 aacagctagc ttaaccgctt cctgccagct agctgctgac aagcccaagc gaatagagtt
    32881 gttttcgata aatgcttttt ttaaattcat ataactatcc tttctaaatc aaattctttg
    32941 gccagacact ttttgcctca ctcctatcta gctgataaag agaaagagct ggaatctctc
    33001 ttcacaactc tcactccatc tatccttact gaaagttgat tgctacagct tagcttacag
    33061 ccaagtggct gctcttaggc tcactatcat ttgccatgag cagcactgat gtcatcaggg
    33121 ccgctctaaa gcaccgcctg tagcttggtt ttgatttcat tgtcgtccat aagattatct
    33181 agtccaacca aatgaccctt tgtacgccca tctaattcat gaatcaggtg attagaagca
    33241 accacaatat catagcctga ggcaagtccc tttgcctcac ccactgagca agaagcagac
    33301 tgaatatcag tcaccccaag ctgacgaagt gcgttttcaa ccttcatttt aataaccatt
    33361 gatgacccca tgccattacc gcatgctgta agaaccttaa ccatttattt tcctccgaat
    33421 atatgataat ttgatatgaa tgaagacctg cagaagtata tcgacaaact cctaccagcc
    33481 tgtgctaaaa gacgaataag cagctattat caccttgctt attgtgcttc accgcggtag
    33541 taagcctctt tatccttagc cctagcaaat tgtagctgtg gaatagcaag taagaagaca
    33601 cacaccacca catagcctgc aataccaagg aacttgaaga gataaccaaa tggaagccaa
    33661 ggaagcacca ggtcaatatt gccatgataa ccacctgtca agcccaacag accaactgcc
    33721 actgcaccta aggcaacctg aagaatacct gatataaagg atagagcaac agctgccttc
    33781 cagccaccac gcttatctgc ataaacagca atcgcagcat tatcaaagaa gaccggaaca
    33841 aatcctgtga tgatcaagat tggattttta aagatcacaa gaagtgcaat agtgattagc
    33901 tgaccgataa gcccaaaggt aaatcctgac aaaacagcgt ttgaagagcc aaagccatat
    33961 gacgctgcaa cgtccaccgc aggaaatgaa cccggaagga gcttacttga aatcccttgg
    34021 aaggcattgg tcaactctga cacaaacata cgcacaccct gcatcaggat aaagagataa
    34081 actgagaaag ttaaggaggt ttgcaaaata tacataaaga aggcctgctt agctggatta
    34141 aaggcaccag cacctataag ttctgcatta gacatcatat ctgggccaag cacagccaag
    34201 atagcaccaa agaaaaccag cattagagtg gcagaagcaa ccaccgtatc atgaaaaatc
    34261 gttaaaaagc ttgctagctt aagattgtca aggttctctt cttttttacc aaagaaaggc
    34321 gccaccttgt caacaaacca gatcgcaaac tgctgctggt gcccaatggc aaagcctcca
    34381 ccacctgtca agcgctgagt cgcctcaact gtcatattgg agctgacagc ccagtaaagg
    34441 ccacagataa taccgaccgc ccaagcacca aaagcatttt gaagctgagg gattaaaaga
    34501 agaacaaaca cagagatggt tgccgcctgc tgcaccatga tatgacccgt aataaagagc
    34561 gtacgaacct ttgtcacctt acgaagcgcc actagcaaaa tattgacccc aaaaccgatc
    34621 aaaagggctg tggtggcaac gctgatggat cccatctcct ctagcttggt attggctgct
    34681 gcaagtccaa agtaagggtc aataactgcg gcctttaatt caaatttctt acccaatgcc
    34741 actaggattg ggcgaaaggt gttaaccaag cccccagcac caacattcaa aatcagataa
    34801 ccaaccgttg ccttaacaaa gccagcaaat acttcatgca ggggcttttt aagcagcaaa
    34861 tacccaatca aaaccaaaag acctacaaag aaagccggat tttgcaaaat atcttgcgaa
    34921 aaccagttta ggggagctat aagcattttc ataagaacta cctcttttca cagttaataa
    34981 atatgatatt ttctatacaa taattgtaaa cgatgtaagc gtttaaaaaa aagaccaaca
    35041 atcacacaaa gaagtgttca aaaatgtact gaagccaatt tccagctagc tctgatcact
    35101 gttaaagcac tatcattaat ctctaattaa taaccaaaca catcacaaca atatcgggct
    35161 aacacaaaaa taggccagcc catactgccc agccaaaacg aaacaagcaa tcaattcaag
    35221 gcacttaacc ctgttttata tcgtacaaag cccttttaag atgattttgt ttgtttccta
    35281 atcgtaaatt agttatctga tccgttctct cctcagatat actcaccctt atctaattct
    35341 actgtcaaat agctacttac tcataagcaa atgaatatta agcaaccacc aagctacaat
    35401 aaaagacctt accctgttgg caagatctta ttcattatac aatttttcct tctgcgacat
    35461 ggactacctc atcacacaag tcttcaatat ctgtcttcag atgtgagctt aaaatcacaa
    35521 gcccattttt gctaacatct aaaagcaatt ttttcgtttg ctccacgctc ctgtcatcta
    35581 atgcattcat tggctcatct aatataagga tcttagggtg atgcatcaag gcctgaatta
    35641 accctaattt tttcttagtg cctagcgatt aatgcttaaa tgctgtttga ctaaactgat
    35701 gtaaatgata aacatctaac caaaaagcta aatcaatatc tctagcctta ggagagattg
    35761 acctaagcaa ctctagattt tgtaacaatg ttaaatgtgc aataaactct ggattctcaa
    35821 tcaaaatccc agcatcctcg atataattat ggtactgtct aattttttta ttgtcctgat
    35881 aaacagctcc ttcatctaat ttgatataac cagctaaggc cttaagtatc aaggtttttc
    35941 ccgaaccatt aatacctacc aaaccataga tattaccttc tttaaaagta agattaatat
    36001 catctagaac aaggttaccc ttatacagtt ttctaccatg ttcaatccgt aacatctcag
    36061 ctctccttat aataattgtc ataaagcata tgtaccaata ctattagcag caggcaccac
    36121 caaacatcaa acaaaaagta acgtatcaag gtgagactag caaacaagat catagctact
    36181 acagcagatg aggcatagcg tatcataaca taaatcaagc aaatatctat agtaagccaa
    36241 gataccataa gataacatag tcgttcaata tgatatggtg caccataata ggtcatcaat
    36301 acacctaata ttaaaacgat aaaaagtaac cactctttaa tatagaaaat cgtactcgtc
    36361 cgccatagct tgttaaaaaa taccaactga cttcgagcat gaaaacgaaa gatttcctta
    36421 gttccttcag ccaaatccgc caaaaatgaa atcgtaaaat aaaagctgtt gaaggacaag
    36481 cctagcaagg tgataacctt gacaaaatca gctgtctccc cttcaatcac tggaaacggc
    36541 attagcaacc gatagcacac taaattatga aaatctcgct ccccagtcat attagcctta
    36601 atcaataaaa gatgtattag taagccagta agacatgctt tcattccaac aaccagcagg
    36661 ttagataatt tcatggtgct tcctcaattt taaaacgatg cacacaccca ctaagcctaa
    36721 ataaggtgat aaaaggtaag gaatatcagc atcactataa gatgttgaca tcaaagaagt
    36781 cataagaaca tatttgggag gtaaatagct atataacaac ggtgacaaag cccacatcaa
    36841 aatcaaatag agcatgcttg acttaataaa ggattgaaga tagtcaacaa gaaaacaaac
    36901 gaaatacgta tgaacgaaca aagctaacga ttttactaag caatagtaag ctataaaggt
    36961 tgttgctcct tgaccaaaaa aacgcaatat tgagttttga tcaaaataag gcattaaatt
    37021 accgttcata tgggcaacac catttagcca agacactaaa gtcaaagcaa atattacaat
    37081 gtaaaaactc agtaaaacat ataagctcaa ctgaagcttt aaaaaaatac accttttacc
    37141 atagtcagac tttctgccaa tgaggtattt aagatgtctt gacttaaggt aatagtaggc
    37201 ataggccact aaaatcatca ctagtggata gataaaagat tgataaaaac taaaatcaaa
    37261 caccacacta tccaaacgta tcatactcaa caatagactt ttctttacct caattccacc
    37321 agataaatct actgcacttg tatcaaaaaa taagatatgc ttcaaactgt caaaataaat
    37381 aaaacctaaa aatagtaacg ggactaatgg ataaaaatag cgaaatggaa ataatctata
    37441 ctgtagcatt tatgaataac tcccctacaa aaaatcaagg aaacgcctcg ttactaactc
    37501 aattcacaat tgtagatatt taccaattgt ctggagacca actaccacta atggttgttg
    37561 ctccgtccca ccaattttca cgtaccagat gcaaggcata aaggtaccca cttttagtat
    37621 cctgtgtata aattcctctg tcgcctgtcc aagttttatc tatatcactt cttctttgac
    37681 cgttactatt agctagatag tgccttacca caatttctct attacgtcct cttgaatcta
    37741 aattaacgac ataataaggc gccgcactct tcacaagata atctttcgtc cttccaaaag
    37801 atgacgtgat tctaaaattt tgcaagtaac caatttgtcg ttctgctata actaaagaac
    37861 taatcaataa tgtagaagct acaattgcca ataatccaat cttaattttg cctaatttta
    37921 ttttttaata atttataatt tttatatatt tagcacatca tcagcgcttc cttgacaatt
    37981 gataatacaa ttcatgctag gcttaatcga taaaactaaa tactagatag taatcaacac
    38041 cagtaaacca agattgtaaa ccctttcttt ttcgtttata ttttaacatt aatattattt
    38101 ttggtcaata ac
//
LOCUS       DARYNN010000018        37802 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.018, whole genome shotgun sequence.
ACCESSION   DARYNN010000018 DARYNN010000000
VERSION     DARYNN010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37802)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37802)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37802
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.018"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(44..754)
                     /locus_tag="TVB59_000823"
     CDS             complement(44..754)
                     /locus_tag="TVB59_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEL1009747.1"
                     /translation="MAKKKGKLTLISLFVLVACLGVYSSIRQSENTSDVSAETVSTSS
                     TQAFIEEIGATASVVAQERDLYASVMIAQAILESANGKSALSQAPYYNFFGIKGAYNG
                     SSVTMTTWEDDGAGNTYYIDQTFRAYPTVADSLYDYTNLLSSDIYAGARKSNTLSYQD
                     ATAALTGLYATDTSYNWKLNNIIETYGLTAYDIVNNQAQEALAAAPLTSVWNPYRKSY
                     TDTETLAIDKAWAQRMGY"
     gene            complement(1201..2559)
                     /locus_tag="TVB59_000824"
     CDS             complement(1201..2559)
                     /locus_tag="TVB59_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anion permease"
                     /protein_id="HEL1009748.1"
                     /translation="MILKSGIRNNHIKWIFTMLPLFVSVLPFISNIEKVFILILISIF
                     LLASNIIPAWYTSILFMTACMIGNIAEKQVILSGITSGAAWLVISGVIIGAAVKHTEL
                     DRLLARFFIPVCMGKYSKVLFGTILLGVVLIFLMPSAMGRVVLLLPILNALSLELGYE
                     KGSKEWEGIVMSGVLATYIPAFYVLPSNVPNNVFTGAILSLYSINISYSRYFLLYFPI
                     LGVGKILILYFTMRLFYRRCKDSICVSKKAIDITKEQKLLIVLLFITLSFWMTEHIHK
                     VPTGWTGMATALIVMLPNSNFMEKQPLRKINFEPFFYVAGIISLGNIAKSSGLANVIA
                     VHLINIVSLETASAFNVLTFFVVLCIILGFIVTLPGVPAVVTPLIDNISGVSNVSKTF
                     LCHIEVIGFSSVFFPFQAPPLMVVLQNENLSKARMTIYCSIVSAIGLLLLLPLALYWK
                     ML"
     gene            complement(2967..3197)
                     /locus_tag="TVB59_000825"
     CDS             complement(2967..3197)
                     /locus_tag="TVB59_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002846351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009749.1"
                     /translation="MKNIDEKILMTDGEIKQLQNKRKKPIIQSKQEERKKRDRRLYEK
                     GAVNQKILKIIEKREQTEENIEVQEEATDTEE"
     gene            complement(3291..3704)
                     /locus_tag="TVB59_000826"
     CDS             complement(3291..3704)
                     /locus_tag="TVB59_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009750.1"
                     /translation="MARKLAIIVIATGILFALIACILFFKKDILQVFPRMDIAWVGFL
                     VVAILLCVSGIWVFSISGKKQDWINETDERESLITAKANMVGYVIQTTLLGIVFFLLV
                     FMGYLNKVSGFSIIGVVLISGIVSWIYHLYLRKVE"
     gene            complement(3739..3936)
                     /locus_tag="TVB59_000827"
     CDS             complement(3739..3936)
                     /locus_tag="TVB59_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004134772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1009751.1"
                     /translation="MKNRLEEIRKENGITQEELASILEVSRQTIGSLENGRYNPSIIL
                     AFKIAKYFSLSIEDIFIYEEE"
     gene            complement(4218..4691)
                     /gene="tnpA"
                     /locus_tag="TVB59_000828"
     CDS             complement(4218..4691)
                     /gene="tnpA"
                     /locus_tag="TVB59_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018373723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HEL1009752.1"
                     /translation="MAKTSYSLSHTKWMCKYHIVFTPKYRRKSIYYKIRQDLIDIFRH
                     LCQYKGVEIIEGHMMPDHVHMLVLLPPKLSISDFMGYLKSKSALMIFDKHANLKYKYG
                     NRKFWARGYYVSTVGLNEKTVAKYIREQEKNDIALDKLSVKEYEDPFSDGSFKTR"
     gene            complement(5143..5742)
                     /locus_tag="TVB59_000829"
     CDS             complement(5143..5742)
                     /locus_tag="TVB59_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEL1009753.1"
                     /translation="MKRRKARRSHREASSWLAAGIVLGSMLLSLWTLASAKDHLKPHA
                     NSSTMLFVSKISHSAQAVAQRNKLYASVMMAQAILESANGQSKLSQEPYYNFFGIKGS
                     YKGKSVILPTLEDDGQGNLYLIDASFRSYGSLTACFEDYARVLSDPLYRPTHRGIHTS
                     YQQATASLTGTYATDTSYGEKLNRIIGDYQLTYFDAPIR"
     gene            complement(6320..8266)
                     /locus_tag="TVB59_000830"
     CDS             complement(6320..8266)
                     /locus_tag="TVB59_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEL1009754.1"
                     /translation="MKIQDLLRKDIMILDLQAVSKEAAIDEMITELVEHGIVHDFDVF
                     KKSILAREEQTSTGLGDGIAMPHSKNVVVDQPAVLFAKSNKGVDYKSLDGQPTDLFFM
                     IAAPQGANDTHLAALAELSQYLLKDGFADQLRKATSPDEVIAVFDAASDQKEVAFVPT
                     NAQEFIVAVTACTTGIAHTYMAEEALKKQAAQMGVGIKVETNGASGVGNRLTADDIKQ
                     AKGVIIAADKAVEMDRFDGKQLIARPVADGIKKSEELISLILNNAGSVYHAKNGAAEQ
                     AKAAQKTSLGGAFYKHLMSGVSQMLPFVIGGGILIALAFLLDNMLGVPKDQLSNLGSY
                     HEIAAIFKHIGGAAFSFMLPVLAGYIAYSIAEKPGLVAGFVAGAIASSGLAFGKVPFA
                     AGGEASLSLAGVPSGFLGALVGGFLAGGVILALRQVLAGLPRSLEGVKSILLYPLLGV
                     LVTGLLMLLINIPMAAINTALNHFLESLSGSSAVLMGLLVGGMMAVDMGGPVNKAAYV
                     FGTGTLAATVASGGSVVMAAVMAGGMVPPLAVFVATLLFKDKFTKEERESGLTNIIMG
                     LSFITEGAIPFGAADPARAIPSFIAGSALTGALVGLAGVKLIAPHGGIFVIALTSNPF
                     LYLLFVAIGAVVSGILFGALRKKA"
     gene            complement(8263..9174)
                     /gene="pfkB"
                     /locus_tag="TVB59_000831"
     CDS             complement(8263..9174)
                     /gene="pfkB"
                     /locus_tag="TVB59_000831"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEL1009755.1"
                     /translation="MIYTVTLNPSIDFIVRIDQLDIGAVNRMVSDDTFAGGKGINVSR
                     ILQRLGIDNTATGFLGGFTGRFIKESLAAESINTDFVTVDQDTRINVKIKSAEETEIN
                     GLGPVISKQQLDHLKAILANVSAEDIVVFAGSAPSSLGNDVYKDLIPLVRQAGAQVVC
                     DFEGQTLLDALAYHPLLVKPNNHELEAIFNVSLNGLDDVETYARKVLDMGAQHVIVSM
                     AGDGALLVTQEATYFAKPIKGQVKNSVGAGDSMVAGFTGAFVKSHSPLEALKWGVACG
                     TATAFSDDLAAIDDIKKTYNEVEVEVR"
     gene            complement(9171..9884)
                     /locus_tag="TVB59_000832"
     CDS             complement(9171..9884)
                     /locus_tag="TVB59_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEL1009756.1"
                     /translation="MAKITAENYVALEDLMQLLSSSESTVRRDLDELEREGKLHRVHG
                     GAELFHSLQEELSNQEKSVKNSQIKEIIAQKAAELVFDNDVIFIDAGTTTEFLLPFLQ
                     LKKVTVVTNSIHHATRLVDMAIKTIIIGGYVKQTTDASIGHVALEQIRQMNFDKAFLG
                     INGIDEAFLTTPDMEEAVIKKAVIANAKITYVLADATKLGHVSFVKVAPIDRVEIITE
                     KSSTVMLKKIKEKAKVIAL"
     gene            complement(10319..11242)
                     /locus_tag="TVB59_000833"
     CDS             complement(10319..11242)
                     /locus_tag="TVB59_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000964166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HEL1009757.1"
                     /translation="MLVYIAGSGAMGCRFGYQISKTNNDVILLDNWEAHLQAIKENGL
                     KISGDVEETVKLPIMKPTEATKEADLIILFTKAMQLPQMLTDIKGIIGPETKVLCLLN
                     GLGHEDVIRHYIPEHNILMGVTVWTAGLEGPGQVHLQGVGALNLQSMDPANQEAGHQI
                     ADLLNDAQLNATYDDNVVPNIWRKACVNGTMNSTCALLDCTIGELFASEDGLNMVKEI
                     IHEFVIVGRAEGVELNEEEITAYVMETSVKAAHHYPSMHQDLVQNHRLTEIDFINGAV
                     NTKGEKLGIDTPYCRLITQLVHAKENILKIK"
     gene            complement(11254..12312)
                     /locus_tag="TVB59_000834"
     CDS             complement(11254..12312)
                     /locus_tag="TVB59_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HEL1009758.1"
                     /translation="MTTTNKETFSSFMNKVLAGTAIAIVVALIPNAILATFLKPLLPN
                     TVAAEFLHIVQVFQFFTPVMAGFLIGQQFKFNPMQQLAVGGAAYIGSGAWAYTEVIQK
                     GVATGTFQLKGIGDLINMMITAALAVLAVKWFGDKFGSLTIILLPIIIGTGVGYIGWK
                     LLPYVSYVTTLIGQGINSFTTLQPILMSILIAIAFALLIVSPISTVAIGLAIGLNGMA
                     AGAASMGIASTTAVLVWATLKVNKSGVPIAIALGAMKMMMPNFLKYPVMAIPMMMTAI
                     VSSLTVPMFNLIGTPASSGFGLVGAVGPIASLAGGSNIVIIIIAWLVIPFGVAFVAHK
                     LCKDILKLYKEDIFVFEG"
     gene            complement(12444..13436)
                     /locus_tag="TVB59_000835"
     CDS             complement(12444..13436)
                     /locus_tag="TVB59_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEL1009759.1"
                     /translation="MQEKIYDITIIGGGPVGLFAAFYAGLRGMTVKIIESLSELGGQP
                     AVLYPEKVIYDIPAYPALTGAELTQKLIEQLSRFDDRIAVCLKEEVLSFEKADGNFVI
                     QTSKARHYSKAIIVACGNGAFAPRTLGLDNEQLFADHNLFYNVHSLNQFAGKRVVICG
                     GGDSAVDWALALDGLAKSVTLVHRRDAFRAHEHSVELLKNSHVTTLTPFVPLALEGEN
                     GFVNKMTIQKVKSEEEITLELDSLIVSFGFSTSNKNLKHWNLDYKRSSLLVSPLFQTS
                     QEGIFAIGDAAAYEGRVDLIATGFGEAPIAVNQAIKYIYPDRDNRPVHSTALID"
     gene            complement(13436..14167)
                     /gene="trmD"
                     /locus_tag="TVB59_000836"
     CDS             complement(13436..14167)
                     /gene="trmD"
                     /locus_tag="TVB59_000836"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEL1009760.1"
                     /translation="MKIDILTLFPEMFAPLEHSIVGKAKEKGLLDIHYHNFRDHAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDTMDSIQATKPRVILLDPAGKPFHQSYAEELALEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDFVLTGGELAAMTMIDATVRLIPNVLGKQASH
                     QEDSFSSGLLEYPQYTRPYDYRGMKVPDVLMSGHHEHIRLWRMEQSLKKTYLRRPDLL
                     ETYDFSDEEKRIFDKIKSGLSEGEN"
     gene            complement(14157..14675)
                     /gene="rimM"
                     /locus_tag="TVB59_000837"
     CDS             complement(14157..14675)
                     /gene="rimM"
                     /locus_tag="TVB59_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEL1009761.1"
                     /translation="MEYFSVGKIVNTQGLQGEMRVLSVSDFTEERFQKGARLALFDDK
                     DRFVQEVEIASHRKHKQFDIIKFKGMYHINAIEQFKGYSLKIAKENQGKLAEGEFYYH
                     QIIGLEVYEKDQLVGEIKEILQPGANDVWVVKRQSKRDLLLPYIPSVVLCVDIEKHRV
                     DVEIMEGLDDED"
     gene            complement(15950..16189)
                     /locus_tag="TVB59_000838"
     CDS             complement(15950..16189)
                     /locus_tag="TVB59_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEL1009762.1"
                     /translation="MDTIENLIIAIVKPLISQPDKLTIKIEDTPDFLEYHLDLDAQDI
                     GRVIGKKGRTITAIRSIVYSVPTLGKKVRLVIDEK"
     gene            complement(16199..16471)
                     /gene="rpsP"
                     /locus_tag="TVB59_000839"
     CDS             complement(16199..16471)
                     /gene="rpsP"
                     /locus_tag="TVB59_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEL1009763.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRAPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLDWLGKGAQPSDTVRSLLSKAGVMAKFHDQKFSK"
     gene            complement(16902..17519)
                     /locus_tag="TVB59_000840"
     CDS             complement(16902..17519)
                     /locus_tag="TVB59_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEL1009764.1"
                     /translation="MSSFGVSHSLLKKLFKILGGLSILFSVMLVVYLIRQLDIINNPK
                     ALAHLIKDHLLIGAICFFILQIVQVVVPIIPGGVTTVVGFLAFGPILGFMLNVFGICI
                     GSSILFQLVRRYGKPFILLFLSMEQLQFYEKKLSTKLFERFFILNMISPLAPADALIM
                     ITGLSQMTYKRFLLIILICRPISILTFSYFWIYGGEFLKHILMHY"
     gene            complement(17512..18735)
                     /locus_tag="TVB59_000841"
     CDS             complement(17512..18735)
                     /locus_tag="TVB59_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1009765.1"
                     /translation="MENWKFALSSIWGHKLRSILTMLGIIIGVAAVVIIMGLGAAMTK
                     RVTDSFSNDQKEVQLYFKAKGDEDNPYAAFAAHENEQEVKPEWLEQIVKAIDGVDSYY
                     YTNNSTSTISFEKKKMDNVAITGVSQDYFKVKKYDIVAGRTLNSKDYKNFSRIILLDT
                     VLADELFGKGNYEQALNKVVSLDSKDYLVVGVYKTDQEVVSFAGGISGGAIMANTQVA
                     SEFHVKEIGSVYLYIGDVKRSLELGNQAAAMLTTLSHVKEGEYAVPDNSQIINDINAQ
                     FSIMTTVVGSIAGISLLVGGIGVMNIMLVSVTERTREIGLRKALGATRLKILSQFLIE
                     SVVLTLIGGLLGLLLAQMCVGVLGNAMQLKGAAVSLDVAAVAIIFSASIGIIFGLLPA
                     NKASKLDPIEALRYE"
     gene            complement(18747..19457)
                     /locus_tag="TVB59_000842"
     CDS             complement(18747..19457)
                     /locus_tag="TVB59_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1009766.1"
                     /translation="MPDEKKELIQLKSIVKSYQNGDQELQVLKGVDLTVYEGEFVAIM
                     GPSGSGKSTLMNIIGLLDRPTSGDYRLNGTQVEILNDRKLAQVRNEEIGFVFQQFFLL
                     AKLNALQNVELPLIYAGVGVSKRRELAKQFLEKVELGMRMKHLPSELSGGQKQRVAIA
                     RALVNNPSIILADEPTGALDTKTGEQIMRLLTELNKEGKTIIMVTHEPEIADFATRKI
                     VIRDGEITADTTESVRID"
     gene            complement(19457..20719)
                     /locus_tag="TVB59_000843"
     CDS             complement(19457..20719)
                     /locus_tag="TVB59_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEL1009767.1"
                     /translation="MSKRGKIKLSTKTKGIIAGAVALTVVVIGGVLWKQQQDTISDQN
                     IKLPYSAVNVTEGTIASSTLLSGTVKALSEEYVYFDASKGSDATVTVKVGDQVTQGQQ
                     LVQYNTTVPQAAYDTAVRNLNKIGRQINHLKTYGVPAATTETSKDEETGQETTTTIQP
                     SAQQNASYAQQLQDLNDSYADAQAEVNKAQQALNETVVVSGVSGTVVEVNNDIDPSSK
                     NSQTLVHVATEGKLQVKGTLTEYDLANIKVGQAVKIKSKVYADQEWTGKISYVSNYPT
                     DANAGGSTAGGSGSSSSTGATYDYKIDITSPLNQLKQGFTVSVEVINEAKHALVPVTA
                     IVNKGKKHFVWVYDDSTAKAKKVEVTLGNADAERQEVSAGLKVGDIVIANPDKNIKEG
                     EKLEDVISADTKASKDSKKSSKESEVIK"
     gene            complement(21034..24210)
                     /gene="carB"
                     /locus_tag="TVB59_000844"
     CDS             complement(21034..24210)
                     /gene="carB"
                     /locus_tag="TVB59_000844"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEL1009768.1"
                     /translation="MAKRTDIKKIMVIGSGPIVIGQAAEFDYAGTQACLALKEEGYQV
                     VLVNSNPATIMTDKEVADKVYIEPLTLAFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     SKAGILQELGVELLGTTLSAIDQAEDRDLFKQLMKELGEPIPESEIVTTVEAAIGFAN
                     AIGYPVIVRPAFTLGGTGGGICSNEEVLRDIVENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDAADNALVVCSMENFDPVGIHTGDSIVFAPTQTLSDVENQLLRDASLRIIRALK
                     IEGGCNVQLALDPNSFSYYVIEVNPRVSRSSALASKATGYPIAKIAAKIAVGLRLDDM
                     LNPVTGTTYAMFEPALDYVVAKLPRFPFDKFERGERRLGTQMKATGEVMAIGRRIEEC
                     LLKACRSLEIGVHHNELKGLDTISDHELVAHIVRAQDDRLFYLSEALRRGYSIEELAG
                     LTKIDLFFLDKLRHIVELEQDLIKKPVDIDLLIEAKRYGFSDQKIAELWQTDAASIRR
                     LRRAYRVLPVYKMVDTCAAEFDSQTPYFYSTYEWENESIKSEKESVIVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEEVMNVIEL
                     EQPKGVILQFGGQTAINLAEQLTKAGVPILGTQLEDLDCAEDRELFEKALKELGIPQP
                     PGKTATNEAEALEAARAIGFPVLVRPSYVLGGRAMEIVENENDLRSYMKTAVKASPEH
                     PVLIDSYILGKECEVDAISDGQSVLIPGIMEHIERAGVHSGDSMAVYPPQHLSKQVQD
                     KIVDYTKRLAIGLNCIGMMNIQFVIQNEQVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQTLKDLGYQDGLYPESSLVHIKAPVFSFAKLAKVDSLLGPEMKSTGEVMGSD
                     LTLEKALYKAFEASYLHMPEYGTIVFTIADDHKSEALILARRFSAIGYQIMATEGTAA
                     FFADQGLDSQLVGKIGDNAHDIPALLRKGQIQAIINTVGTKRVTDKDGQMIRSSAIEQ
                     GVPLFTALDTAVAMLRVLESRTFSIEAI"
     gene            complement(24628..25719)
                     /gene="carA"
                     /locus_tag="TVB59_000845"
     CDS             complement(24628..25719)
                     /gene="carA"
                     /locus_tag="TVB59_000845"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEL1009769.1"
                     /translation="MAKRLLILEDGTIFEGKPFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQLLVFTYPLVGNYGINRDDYESIAPTCKGVIVSEVSRIASNWRQQMTLDEFLK
                     HKGIPGISGIDTRALTKIIRQHGTMKATMADDGDTLEHLKDQLRATVLPTNGIEQVST
                     KTAYPAPGVGKNIVLVDFGLKHSILRELSKRQCQMTIVPFDITAEEILQLNPDGLMLS
                     NGPGNPEDLPEALEMIRGVQGKIPIFGICMGHQLLSLANGAKTFKMPFGHRGFNHAVR
                     EIATGRIDFTSQNHGYAVERDSLPDCLMVTHEEINDKTVEGVRHRHVPAFSVQFHPDA
                     APGPHDASYLFDEFLDMIDAWQLEQQGKC"
     gene            complement(25742..26677)
                     /locus_tag="TVB59_000846"
     CDS             complement(25742..26677)
                     /locus_tag="TVB59_000846"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEL1009770.1"
                     /translation="MSVVNNRVALKHLVSMEHLTNEEVLGLISRGSEYKAGKVAIKDN
                     SRHFAANLFFENSTRTHKSFEVAENKLGLRVLDFNADTSAVNKGETLYDTVLTMSALG
                     TEICVIRHPEDDYYQQLIDSPTITASIVNGGDGSGQHPSQCLLDLLTIYEEFGHFDGL
                     KIAIAGDLTHSRVAKSNMQILKRLGAELYFYGPEQWYSSEFDSYGRYMAIDHIIDQLD
                     VLMLLRVQHERHDGSQSFSKEDYHRQFGLTEERYRRLKDSAIIMHPAPVNRDVEIADH
                     LVEAPKARIVAQMANGVFVRMAIIEAILNGRNDKV"
     gene            complement(26735..27994)
                     /locus_tag="TVB59_000847"
     CDS             complement(26735..27994)
                     /locus_tag="TVB59_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEL1009771.1"
                     /translation="MKDVIYDVEEVPKAGILLGLSFQHLFAMFGATVLVPILVGIDPS
                     VALLSSGLGTLAHLSVTTFKIPAYMGSSFAYIAAMQMLMKTDGIGAVAQGAITGGLVY
                     LVVALVVKAIGNEWIDKILPPVVVGPIVMVIGLSLASTAVSDVMLKDGKYNLLYLLIG
                     LVTLLAIIFFNIYGKGIVAIIPILLGLLVGYLFAILVGMVTGQSIVDFTQVAKAQWLS
                     VPAVAIPFLTYDITLYPSAILTMAPIAFVTMTEHFGHIMVLNSLTKRDYFKDPGLEKT
                     LTGDGLAQVIAGFLGAPPVTSYGENIGVMALNKIFSVYVIAGAAVIAGLLSFVGKVSA
                     LIQSIPTPVIGGISIALFGVIASSGLKILIEAKVDMDNKKNLLIASVILVSGIGGLML
                     QINGLQISGVAFSTLLGIILYQLLPEN"
     gene            complement(28010..28531)
                     /gene="pyrR"
                     /locus_tag="TVB59_000848"
     CDS             complement(28010..28531)
                     /gene="pyrR"
                     /locus_tag="TVB59_000848"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEL1009772.1"
                     /translation="MKSKVIVDELTMKRAITRITYEIIERNKQLDNVVLVGIKTRGVY
                     LARRIQERLEQLESLHLAVGELDTKPFRDDMRVEEDTTSMPVDITGKDIILVDDVLYT
                     GRTIRAAIDNLVSLGRPGRVSLAVLVDRGHRELPIRADYVGKNIPTSKTEEIVVEVVE
                     VDGQDRISIVDPG"
     gene            28893..29507
                     /locus_tag="TVB59_000849"
     CDS             28893..29507
                     /locus_tag="TVB59_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEL1009773.1"
                     /translation="MNDITRKINHKQLIQITTILGIIVTIVILFYLQQHPNLFAVGGP
                     FQTYLMELGILAPCLFILLQIIQVVYPIIPGGLTCVLGHVVFGPFWGFLYNTLGIFIG
                     SLLSFMLARKYGEQFAKAFVSDDTYNKYIPYLNKGKYFERFLITAFILPGFPDDFLCM
                     VAGLSSMSIKTFTSIFLISKPITLYIYTLLAYQGIQIVGQVLQS"
     gene            complement(29588..30478)
                     /locus_tag="TVB59_000850"
     CDS             complement(29588..30478)
                     /locus_tag="TVB59_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEL1009774.1"
                     /translation="MEIKITESGHRLDKALADLTPLSRSQANDQIKQKRVLVNGLPKK
                     AKYIVQVGDCISYHIPEESSLDYQAQDIPLDIVYQDDVLAIINKPQGMVVHPSAGHST
                     GTLVNALLYHIKDLSSINGVIRPGIVHRIDKDTSGLLMVAKTDKAHQLLADELKAKKS
                     LRKYVAIVHGNLPKDRGVIEAPIGRSEKDRKKQTVTAKGKEALTLFKVLERFGHYTFV
                     ELQLETGRTHQIRVHMAYIGHPLAGDPLYGPRKTLAGKGQFLHAQTLGLTHPVTGEEL
                     VFTVEPPEIFQRTLEQLRQG"
     gene            complement(30468..30926)
                     /locus_tag="TVB59_000851"
     CDS             complement(30468..30926)
                     /locus_tag="TVB59_000851"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEL1009775.1"
                     /translation="MKRISFIMAAIVLMILDQLSKWWTVTHIELGQVKPFIPGLVSLT
                     YLQNRGAAFSILQNQQWFFTIITVLVVGYAIYYVLKHPKASFWLQLSLLLIISGGLGN
                     FIDRLRLSYVVDMIHLDVINFAIFNVADSYLTIGVLLLVICLWKEEDYGN"
     gene            complement(31154..32083)
                     /locus_tag="TVB59_000852"
     CDS             complement(31154..32083)
                     /locus_tag="TVB59_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEL1009776.1"
                     /translation="MNIQQLRYVVAIANNGTFREAASKLFVSQPSLSVSVKDLETELG
                     FQIFRRTTAGTVLTSQGLLFYEKALEVVKCFDSLEKEFSQSALEPNEFSIASQHYDFL
                     PALITAFSQKHAGHKVFRVFESTTMQILDEVAQGNSELGIIYLNAQNRQGLFQRMDKL
                     ALDYVELLSFTTHIYLSKNHPLAQRKALFLEDLQGLPAVRFTQEKEEYLYYSENFIDT
                     SKSPHIYTVSDRATLNGILERTAAFATGSGFLDQQSVNGIKVIPLRDHMEHKMIYVKR
                     RDKNLSAAALHFVTILQDYFEHRKEKQAIDNGT"
     gene            complement(32490..32783)
                     /gene="rpmA"
                     /locus_tag="TVB59_000853"
     CDS             complement(32490..32783)
                     /gene="rpmA"
                     /locus_tag="TVB59_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEL1009777.1"
                     /translation="MIKLNLSNLQHFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVSG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(32805..33137)
                     /locus_tag="TVB59_000854"
     CDS             complement(32805..33137)
                     /locus_tag="TVB59_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEL1009778.1"
                     /translation="MIKVRLTKDAAGWTEMLITGHAGSGEYGFDVVCASVSVLAFNLV
                     NSVEQMTGLEPALEMVDGGGFLRVTKPEGFTEQQEQVWQILFESVVIGLENLAEHLSE
                     YVQKPVMN"
     gene            complement(33150..33464)
                     /gene="rplU"
                     /locus_tag="TVB59_000855"
     CDS             complement(33150..33464)
                     /gene="rplU"
                     /locus_tag="TVB59_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEL1009779.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAIYVEKIDAEAGAEITFNEVVLVG
                     GDKTVVGTPVVEGATVVGTVEKQGKQKKVVTFKYKPKKGSHRKQGHRQPYTKVVINAI
                     KA"
     misc_feature    complement(33498..33572)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(33694..34887)
                     /locus_tag="TVB59_000856"
     CDS             complement(33694..34887)
                     /locus_tag="TVB59_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HEL1009780.1"
                     /translation="MLKDFQYKKTMLSVLTLIVVILVFGLAFDLLGMSKKGTQTKSKT
                     PQKTQTARVVANGDILIHDILYMSAKKADGSYDFNPYFEYVKDWISQADLAIGDYEGT
                     ISPDYPLAGYPLFNAPEAIAAALKHTGYDVVDLAHNHILDSRLEGALNTKRVFADMGI
                     DSIGIYEQDRSKENILIKKVNGIKIAILGYSYGYNGMEATLSQEEYDKHLSDLNEEKI
                     QKDILRAEKEADITIVMPQMGTEYALEPTAEQKTLYRKMIDWGADVVLGGHPHVVEPA
                     ETIVKDKEKKFIIYSMGNFISNQRLETVDDIWTERGVLMDLTFEKKGQKTKIKTVKAH
                     PTMVLAKPKGLYGSEGYELYSYRTMVLEDFIKGGRYYDKIDPETQEKAAIAYKEMNAL
                     VNLKW"
     gene            35152..35769
                     /locus_tag="TVB59_000857"
     CDS             35152..35769
                     /locus_tag="TVB59_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3862 domain-containing protein"
                     /protein_id="HEL1009781.1"
                     /translation="MKHNSFSRSLLLPLLICSLSACSSHTEKKDHTKDATAITDTRKA
                     EHQDIRANMEKVKLATASTDFKGGSSLEELITIFGQPSQHEEKAAGSVTLDSYTWQFD
                     HVTVNINLYENSSIVKTIANFAFIRDLTLSLKDYNSLKKGMTYDEVKQLLTEPDNYSQ
                     ANSSEKETIQAIWISGLKAQTQGANIALTFENNQLTEMSQVGLED"
     gene            complement(36067..37296)
                     /locus_tag="TVB59_000858"
     CDS             complement(36067..37296)
                     /locus_tag="TVB59_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1009782.1"
                     /translation="MRGLIKNVVFRTLTVSNFLSALGSYIYNIVFIIYATTLPYSHIA
                     VFIANIITIIPMVFTFWIGVKADKTKRKTRNLIVIGFIQSLLFTLVALLMTNQTFLVF
                     AFVGFLNVVSDILSDYKNGLRLPIMQKNIESEKLYEAYSFAQFIGYLSSIAGQALGVW
                     LLTTSGNNYAFVALINAISFLLSSVVLLKNRQKLRHDVVEASEAGVSLMKQFKVMYTR
                     MTETFKKIDHISFVMLLLSILTLNAIGGAINSIYHFYLMDHQLFHFHYGQSLVIVDAV
                     TIIGAMLGNLTPKDYFSRLSISKLVQTQGIAFLLVGVSNALQLPAIIGVLCLAFAAYI
                     MGKATPKLDALLMENLPSDMLAQSNNFLGLLFSLSLPVGVFIFSFLALYNMTLCWILF
                     MVLSLAALALSTSSTRG"
     gene            complement(37331..>37802)
                     /locus_tag="TVB59_000859"
     CDS             complement(37331..>37802)
                     /locus_tag="TVB59_000859"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HEL1009783.1"
                     /translation="VNLGLNGLAGVLFYLSSISYDNEIIEKGIDFILESLVEDSDGNR
                     GVLISENSVSPYLSNGTAGIVQLLIYVNSDKYIKDIKNLSESLLVEFAQFSGLWNGML
                     GIAMTLLQVFRLTNDTLYLEKACELLISSKIMSEHHIKLQYEFRYAVSIFNQVK"
BASE COUNT        11459 a         8591 c         6541 g        11211 t
ORIGIN      
        1 gctagaactc aagccttgga gtgctaagtc atttttctat tctttagtag cccattcgtt
       61 gtgcccatgc cttatcaata gcaagggttt cagtgtctgt atagctcttg cgataaggat
      121 tccagacaga ggtcaaagga gccgcagcaa gcgcttcttg cgcctgatta tttactatat
      181 cataggccgt tagaccgtag gtctcaatga tgttgtttaa tttccagtta tagctagtat
      241 ctgtagcata caagcctgtt aaagctgctg tagcgtcctg ataagacaag gtatttgact
      301 ttctagcacc tgcataaata tctgagctaa gcaaattagt gtaatcatat aaggaatcag
      361 ccactgtcgg ataagctcta aaggtttgat cgatgtagta agtatttcca gccccatcgt
      421 cttcccatgt tgtcatcgtc actgatgacc cattataagc ccctttaatg ccaaaaaaat
      481 tataataagg tgcttgactt aaagctgatt taccgttagc tgactctaaa atagcttgag
      541 caatcataac cgaagcatac aagtctcttt cttgagcaac aacactagca gttgctccaa
      601 tctcttcaat aaaggcttgc gttgacgacg ttgacacagt ctctgctgag acatctgatg
      661 tattttctga ctgtctaatt gaactataaa cacctaagca ggctactaga acaaaaagac
      721 tgataagtgt gagcttacct ttcttttttg ccatttatca ttccctcttt ttttgataaa
      781 tagattatag cacagaatgc tcataaaaag acttatccac aaacaattta atcatattga
      841 taacttttgt ctttaaatcg aaatatttta atgtaaagaa ggcttaccaa gtccataaag
      901 cgaaggcttt tcataatctt ttacgcctta tttgctatat cgccttgtaa tagcttcaat
      961 acctttgaaa ggttattaca cctactattg ttctttatgc ctgtctgtta agtattttcc
     1021 atttaactgc ctttattttt taggtaaaga aaaaacagta aaccattaat ttactgtttc
     1081 ttaattgata tttaatattt tcttataact attgatgtta aataaatgaa aatatatcat
     1141 tcttgtttac taccaacttc taactagtat agtacgagga tataattaaa tcttcgtctt
     1201 ttacaacatt ttccaatata acgctagtgg taacaacaat aataatccaa tagctgatac
     1261 aatcgaacaa tatattgtca ttcttgcttt tgataaattt tcattttgta aaaccaccat
     1321 caagggtggt gcctgaaatg ggaaaaatac acttgaaaaa cctataactt caatatgaca
     1381 taaaaatgtt tttgaaacat tactaacgcc tgaaatatta tcaatcaaag gtgtaactac
     1441 tgccggaaca cccggtaaag ttactataaa tcctaatata atacacaata caacgaaaaa
     1501 agttaaaaca ttaaatgcac ttgctgtttc caaagaaaca atattgatta aatgcacagc
     1561 aatgacattt gcaagtcctg aagattttgc tatattccct aaacttatga ttccagctac
     1621 ataaaaaaat ggctcaaaat ttatttttct taaaggttgc ttttccataa aatttgaatt
     1681 tggtaacatt acaatcaagg cagttgccat tcctgtccaa ccggttggta ctttatgaat
     1741 atgttctgtc atccagaaag acagagttat aaataacaaa actattaaca atttctgctc
     1801 ttttgttatg tcaatggctt ttttggacac gcaaatcgaa tctttacatc ttctataaaa
     1861 taaccgcatt gtaaaatata aaatcaatat ttttccaact cctaaaatag ggaagtacaa
     1921 gagaaagtat ctgctatagg atatatttat ggagtaaaga cttaaaattg ctccagtaaa
     1981 aacattattt ggaacattgg aaggtaatac ataaaatgca ggtatatagg ttgctaaaac
     2041 ccctgacata acaattcctt cccattcctt acttcctttt tcataaccta attctaaaga
     2101 tagggcattt agaataggta aaagcaaaac tactctaccc attgctgatg gcatcaaaaa
     2161 aattagtacc actcctagca aaatcgtccc aaataacact ttagaatatt tccccatgca
     2221 caccggaata aaaaatctcg caagtaatct atcaagttca gtatgcttta ctgccgcccc
     2281 tataataaca cctgaaataa caagccatgc tgcacctgaa gttatccctg ataagatgac
     2341 ttgcttctca gctatattcc ctatcataca agctgtcata aataaaatgc ttgtatacca
     2401 tgcaggaatt atattgcttg ccaaaaggaa gatagatata agaatcaaaa taaaaacttt
     2461 ctctatattt gaaataaatg gtagtacaga tacaaacaac ggtaacattg taaatatcca
     2521 ctttatatga ttattcctaa ttccagattt taaaatcatc ctccattttt gacctccaac
     2581 tctaatttat ttcatagtat tataccatat ttattttcat tttataggtc tacctcttgc
     2641 ttctttgtct gtgttaatcg cttttcttgt ttttataact gctctataca agtcttaact
     2701 ttttctgcct gtttaatttt ttctcgtatc tctaatattt tattgtgtaa gctctttttt
     2761 tctttcttca tattggcgac ttccgatttt catttgctaa tgactaaggt cttgctttcg
     2821 cccaaatgct cttttagata tttcttggca ctctcaaata aaataatctc tgctgtatca
     2881 acgttagctg atatgccctc tgcaagagcc ttcggagaac gcacgcacct gttgaggtgt
     2941 atatgtacac tcttgtaaac aagggactat tcctctgtgt ccgttgcttc ctcttgcact
     3001 tctatgtttt cttctgtttg ttctcttttc tctatgattt ttaggatttt ttgattgact
     3061 gctccctttt cataaaggcg tctatctctc ttttttctct cttcctgttt cgactgaatg
     3121 atgggctttt ttcttttgtt ttgtaactgc ttgatttctc catctgtcat taaaattttt
     3181 tcatctatgt ttttcatttt ctattttcct ctctttctgt tttgagcaac aaaaaaacag
     3241 taaaccattt ttttgattta ctgttttcta ataaatatta tcttagttat ctattctact
     3301 tttcgtaaat ataaatgata aatccatgat acgataccac ttatcaaaac aactccaatt
     3361 atagaaaacc cagaaacttt gtttaaatag cccataaaaa ctagaagaaa aaaaactatt
     3421 cccagtaaag ttgtttgaat cacatatcct accatattag ccttagctgt tattaaggac
     3481 tctctttcat cggtttcatt tatccaatct tgttttttac ctgaaattga aaatacccat
     3541 attccactaa cacacagaag aatagcaaca acgagaaagc ctacccatgc aatatccatt
     3601 cttggaaata cctgtaaaat atctttttta aaaaataata tgcaagcaat caaggcaaaa
     3661 agtattccag tagcaataac tataatagct aactttcttg ccataaccat ctcttttttt
     3721 atatttcttt tcattttttt attcctcctc gtatataaag atatcttcaa tgcttaaact
     3781 aaaatactta gcaattttaa aagctaaaat aatggaagga ttataccttc cgttttctaa
     3841 agaaccaatt gtctgccttg atacttcaag aatagatgct aactcttcct gtgttattcc
     3901 attttctttt ctgatttcct caagtctatt tttcacattt aatgacctcc tgcaacaatg
     3961 acaagctaac tttacatata gtataatgtt ttttagagaa aatggcaagt atactttcca
     4021 taaaatcgtt tccttatagg tctagccctt acttttttac atgtacgact cctctatatc
     4081 tgcattttcc tcttatactt ctgtctgttg atgagcactt gcttctcttt gtgatgatat
     4141 ctttactatg cttttcattt ttgggatttt tatcttaatt ttgagtagtc ataactaatg
     4201 cccgtaaaaa cgggctttta tcttgtttta aaactgccat ctgaaaatgg atcttcatat
     4261 tctttaacac tcaacttatc aagtgcaatg tcatttttct cctgctcgcg aatatatttc
     4321 gctaccgtct tttcgttcag tccaacggta ctaacatagt agcctctagc ccaaaacttt
     4381 cgatttccat acttatattt taaattagcg tgtttatcaa atatcatgag agcactttta
     4441 cttttcaaat accccatgaa atcggaaatc gaaagttttg gaggtagcaa gacgagcata
     4501 tgaacatgat ctggcatcat atgtccctca atgatttcca cgcccttgta ttgacatagg
     4561 tgacggaaaa tatcaattaa gtcctgtcta attttgtagt aaatggattt tctgcggtac
     4621 tttggtgtga aaactatgtg atatttgcac atccatttgg tatgtgataa actgtaactg
     4681 gttttagcca tctctttttc ctccttgatc taacctgaac aattagatta taacaggaaa
     4741 aagaaatgga agctcaaagc cttgtcagcc accagcatag ctggtggttt tcttgttttt
     4801 ctctacgaga aaaactggct cgaagccata atgaatcaaa agaagatagc atttctgcta
     4861 tctcactgtt agccactact tacaggtaaa aatacacctt gtctatttgt agtttaacta
     4921 tccatttaat ccatcaataa gccaaaccag accgtttaat catctaccca gccttacaca
     4981 tagtattttc tcacatcatt tgtagaattg ctttctcctt gcatgtcacc atctcgtctt
     5041 aaacgttcgt aaagggctgt ttgatctttt ctaactattt tagaaaatta ttttgctgtt
     5101 ctgatgaggt taatctcgtt agatcagtca tgctggaggt agctaccgta tgggagcgtc
     5161 aaaataagtc agctgataat cccctataat acgattgagc ttttcgccat agctagtatc
     5221 tgtggcatat gtgcctgtta aactagcggt ggcctgctga taacttgtat gaatacctcg
     5281 gtgagtaggg cgataaagcg ggtcactcaa aaccctagca taatcctcaa agcaggctgt
     5341 taagctgcca taggaccgaa aagaagcgtc aattagataa aggttgcctt ggccatcatc
     5401 ttccaaggta ggtaaaataa ctgattttcc tttatagctt cctttgatac caaaaaaatt
     5461 ataatagggc tcttgactta gcttagattg accatttgct gactccaaaa tagcctgtgc
     5521 catcatgact gaggcataga gcttgtttcg ctgcgcaact gcctgagcgg aatgactaat
     5581 cttgctcaca aatagcatgg ttgagctatt ggcatgaggc ttaaggtgat ccttagctga
     5641 cgctaaggtc caaaggctaa gcaacatgct gcctaaaaca ataccagcag ccagccaaga
     5701 gctagcttcc ctgtggcttc ttctagcttt cctcctcttc aacagaaata tcctcacttc
     5761 cttgctttta aacctagtat agcaaaaatt aaaagcaaaa tgtagccaga ccacatgctc
     5821 acctcaaaaa caggccttat gacttctaaa aagacctagc agccacaaca ggcgcataaa
     5881 aagtttttaa caagaaaaga agactttgct gtatttcaat ccacgctcct gcaaagggag
     5941 cgatacaaaa aataaatgga atatctacaa tcaaatgatt tcaatgttta gctatttcaa
     6001 gaatatatct tatttttgat agatgttact ataggaaaaa cgttgatagt atctacttta
     6061 attgatacta taattcgaaa ataactgttt cgcacgtttg gtgtggctta gtttagcagg
     6121 gctattgggt cactgcttag ctattctaga tcagattgat tctctctaaa tattagcttt
     6181 tcgccagtca tcactactag caacaaacaa aacgcacgac atcatgtaaa aacaggctga
     6241 tgtcatgcgt ctgatgtttt attaagacta ggtctaattc agaagctttc cctagtactt
     6301 gtggctttat agccagtaac taagcttttt tacgaagtgc gccaaagaga ataccagaaa
     6361 ccactgctcc aatagcgaca aacaataggt ataagaaagg attgcttgtc aaagcgataa
     6421 cgaagatacc gccatgtggt gcgattaatt tgacacctgc tagaccaaca agagcacctg
     6481 ttagggcaga gccagcgata aagcttggga tagcgcgtgc tgggtctgct gcaccaaacg
     6541 gaatggctcc ttctgtaatg aaggaaagtc ccataataat gttggtcaag ccagattcac
     6601 gctcttcctt ggtaaatttg tctttaaata agagtgttgc cacaaaaaca gctagaggag
     6661 gcaccatacc acctgccatg acagcagcca taacaactga cccaccgctt gcaacggttg
     6721 cagcaagtgt tcctgtacca aagacatagg ctgccttatt cactggacca cccatatcaa
     6781 cagccatcat gccgccaaca agaagtccca taagaactgc agagctacct gacagacttt
     6841 ctaagaagtg gttcaatgct gtattgatag ctgccatagg aatattgatc agcagcatca
     6901 aaagacctgt cacaagaaca ccaagtaatg ggtaaagaag gattgacttg accccttcaa
     6961 gcgaacgcgg aagccctgca agcacttgac gaagagcaag aattactccc cctgcaagga
     7021 agccacctac aagcgcacca agaaatccag acggtactcc cgctaatgat aggctagcct
     7081 caccgccagc agcaaatgga acctttccaa aagcaagacc gctagaagca atggcacctg
     7141 ccacaaagcc tgccacaaga cctggctttt cagcgataga ataagcaatg tagcctgcta
     7201 gcactggcaa catgaatgaa aaggccgcac caccaatatg tttaaagata gctgctattt
     7261 catggtagga tcccaaatta gacagctgat cctttggtac cccaagcatg ttgtcaagca
     7321 agaaggcaag agcaattagg attccaccac caattacaaa tggcagcatt tgtgatacac
     7381 cactcatcag gtgcttgtag aaggctccgc ctaggcttgt cttttgagct gcttttgctt
     7441 gttcagcagc gccattcttg gcatgataaa cactaccagc attgtttaaa atcagtgaaa
     7501 tcaattcctc gcttttctta ataccatctg ctacaggacg agcaatcaat tgcttaccat
     7561 caaagcgatc catctcaacc gccttatcag cagcgataat cactcccttg gcctgcttga
     7621 tgtcatcagc tgtcaggcga ttgccaaccc ctgaagcacc gttggtttca accttgatgc
     7681 cgacacccat ctgtgcagcc tgctttttca aggcctcttc tgccatataa gtatgtgcaa
     7741 tacctgtcgt acaagctgtc acagcaacga taaactcctg agcatttgta ggaacaaaag
     7801 ctacctcttt ctgatcagaa gccgcatcaa agacagcaat cacttcgtct ggacttgttg
     7861 cctttcgcag ttgatctgca aagccatcct ttaataggta ttgggataat tcggctaagg
     7921 ccgctaagtg agtatcattt gccccttgag gtgctgcaat cataaagaac agatcagttg
     7981 gctgaccgtc taaggatttg taatcaacgc ccttgttaga ttttgcaaag agcactgctg
     8041 gctggtcaac aacaacattt tttgaatgcg gcatagcaat gccatcgcca agacctgttg
     8101 aggtttgctc ctcgcgagct aagatactct ttttaaacac atcaaagtca tgtacaatcc
     8161 catgctctac tagttctgta atcatttcat caattgcagc ctcttttgaa acagcctgca
     8221 aatcaagaat catgatgtct tttcttaata aatcctgtat tttcatcgaa cctctacctc
     8281 aacctcatta tatgtttttt taatatcatc aattgctgct aaatcatctg aaaaagcagt
     8341 tgctgttccg caggccactc cccattttag agcctctagc ggactatgac ttttgacaaa
     8401 ggcacctgta aagcctgcca ccatcgaatc accagctcca acagaattct tcacctgccc
     8461 tttaataggc ttagcaaaat aagttgcttc ctgagtgacc agcaaggcac catcaccagc
     8521 catcgaaacg ataacatgct gcgctcccat gtcaaggacc ttacgagcat atgtttcaac
     8581 gtcatctagc ccatttaagc tgacgttaaa aatagcttct agctcatggt tattaggctt
     8641 tacgagcaat gggtgatacg ccaatgcatc tagcaaggtc tgtccttcaa aatcacagac
     8701 cacctgtgcc ccagcttgtc tgaccaatgg gatcaagtcc ttatagacat cattgcctag
     8761 acttgaaggc gctgagcctg caaaaacaac aatgtcctct gctgacacat ttgccaatat
     8821 agcctttaaa tgatccaatt gctgctttga aatcactggt ccaaggccat taatctctgt
     8881 ctcctctgct gatttgatct taacattgat ccgcgtatcc tgatcaaccg ttacaaagtc
     8941 agtattgatg ctctcagcag ctagactttc cttaataaaa cgcccagtga agccgcctaa
     9001 aaagccagtc gctgtattat caatgcctaa tcgctgtaga atgcgactaa cattaatccc
     9061 ctttcctcct gcaaatgtat cgtcactgac catgcggtta accgctccaa tatctaattg
     9121 gtctattctg acaataaagt ctatagaagg atttaaggtt actgtgtaaa tcatagtgca
     9181 attaccttcg ctttttcctt gattttcttc agcattactg tcgaagattt ctctgtaatg
     9241 atttcaaccc tatcaattgg agcaaccttg acaaaggaaa catgaccaag ctttgttgca
     9301 tcagctaata cataggtgat tttagcattg gcaatgacag cttttttaat aacagcctcc
     9361 tccatatccg gagtggttaa aaatgcctca tcgataccat tgataccaag aaaagcctta
     9421 tcaaaattca tttgcctaat ttgctccaag gcaacatgac cgatgcttgc gtctgttgtc
     9481 tgcttgacat agccaccaat aataatggtc ttgatcgcca tatcaaccag tctagtcgca
     9541 tgatgaatag aattagtcac tactgttact ttttttaatt gcaaaaaagg aaggagaaat
     9601 tcggttgttg tcccagcatc aataaagatg acatcattat caaaaaccag ctctgctgcc
     9661 ttttgagcga tgatttcttt tatttgactg tttttgacag atttttcctg attagataat
     9721 tcctcttgta aggaatgaaa aagctcggca cctccatgca ctcgatgaag cttgccctca
     9781 cgctccagct catctaaatc tctacgaaca gttgattctg acgagcttaa cagctgcatt
     9841 aaatcctcta gcgcaacgta attctcagct gtgatttttg ccataatgag ctgttttcgt
     9901 tttgatttta agataaaacc acccctttgt ctgaaatcgt ttacagctct attatactac
     9961 actttattcc aaagtcaagc actatctttt aaaaacattc aaattcaatc ttagacctct
    10021 attgccttaa caataactgc caattgatca gtcattgtcc ccgtcaatac ctgtagacta
    10081 atgattaacg acttttttat taactagagc ccaaaaagcg ctcacctgtt gcaaaagtct
    10141 gaaacacaat agtctcttac aaatcaaaaa gcaacggatt tactgtcgtt gcttcataat
    10201 gagagtctag gacaaagtct tttcagccaa caagacaaaa cgagagagtc acctattgtg
    10261 agcctctcgt tttattgtac tgagaaattg ttttatccca gactccttat gtctaaacct
    10321 atttgatctt caaaatattc tctttggcat ggactagctg tgtaatcaag cggcaataag
    10381 gggtatcgat accaagcttt tcacccttgg tatttaccgc accgttgata aagtcaattt
    10441 cagtcaagcg gtgattttga acaagatcct gatgcattga tgggtagtga tgagcagcct
    10501 tcactgaggt ttccatcaca taggctgtga tttcctcttc attaagctcc accccctcag
    10561 cacgaccaac aataacaaac tcatgaatga tttctttaac catgtttaaa ccatcttcgc
    10621 tggcaaataa ctcaccaatc gtgcaatcaa gtagggcaca ggttgagttc attgtaccat
    10681 tgacacaggc ttttctccaa atatttggaa caacattatc atcataagtt gcattcaatt
    10741 gagcgtcatt tagcaagtca gcaatctgat gtcctgcctc ttggtttgct ggatccatgc
    10801 tttgtagatt aagcgcacca actccttgta agtgtacctg accaggtccc tcaagacccg
    10861 ctgtccaaac ggtaacaccc attaaaatat tatgctctgg aatatagtga cgaatcacat
    10921 cttcgtgtcc aagaccattt aataggcaaa gtaccttggt ttcagggcca ataatacctt
    10981 taatatcagt cagcatttgt ggcagctgca tggctttggt aaacaaaatg ataaggtcag
    11041 cttccttagt agcctctgtc ggcttcatga taggaagctt tacggtttcc tctacatcgc
    11101 ctgaaatctt caagccattc tctttgatcg cttgaagatg tgcttcccaa ttatccagta
    11161 aaataacgtc attgtttgtt tttgaaattt ggtaaccaaa tcgacagccc atagctcctg
    11221 agcctgcaat ataaactaac atgctttttc ctcttatcct tcaaatacaa aaatatcttc
    11281 tttataaagc tttaaaatat ccttacaaag cttatgtgcc acaaaagcaa ctccaaatgg
    11341 aatgaccaac caagcaatga taatgatcac aatattgctg ccaccggcaa gtgaagcaat
    11401 aggaccaact gcaccaacaa gaccaaagcc agatgaggct ggtgttccaa tcagattaaa
    11461 cattggaacg gttaaagagc taacaatagc tgtcatcatc attggaatag ccataactgg
    11521 gtattttaag aagtttggca tcatcatttt catagcgcca agggcaatgg caattggaac
    11581 acctgatttg ttaaccttta acgttgccca cacaagaaca gcggttgttg aagcaatacc
    11641 cattgaggcc gcaccagctg ccataccatt taagccgata gctaaaccaa tcgcaaccgt
    11701 tgagatcgga ctcacaatca aaagagcaaa ggcaatggca atcaaaatag acatcagaat
    11761 tggctgaagc gttgtaaatg aattaatgcc ttggccaatc agggtcgtca cataagaaac
    11821 gtaaggaagc agcttccagc caatgtaacc cacacctgtt ccaataataa ttggcaacaa
    11881 aataatggtt agagacccaa atttatcacc aaaccacttc actgctaaaa cggcaagcgc
    11941 agctgtgatc atcatattaa tcagatcacc aatgcccttt agctggaagg tcccagtggc
    12001 aacacctttt tggataacct ctgtataagc ccaagctcca gaaccgatat aagctgcccc
    12061 gccgacagcc agctgctgca ttgggttaaa tttgaactgc tgtccaatca aaaaaccagc
    12121 cataactggc gtaaagaatt ggaaaacctg gacgatatgt aaaaattcag ctgctacagt
    12181 atttggcaaa agcggcttta aaaacgtcgc taaaatagca ttcggaataa gtgcaactac
    12241 aatcgcaatt gctgtaccag ctaagacctt attcataaac gagctaaagg tctctttatt
    12301 tgttgttgtc atttcatgac ctctcttaat attatagtgt gaaaaacatc acgaaagtat
    12361 tctaacataa aaagagcatt ttgtcacagc tattttaatt tttatcaata cgtacagaat
    12421 attcaattaa atgtcatata atattaatca atcaaggctg ttgaatgaac aggtctatta
    12481 tctctatcag gataaatata cttaatcgct tggttgacag caatcggtgc ctcaccaaag
    12541 ccagtggcaa tcaaatcaac cctgccttca taagctgctg cgtcaccgat cgcaaaaatc
    12601 ccttcctgac ttgtttgaaa gaggggagag acaagaagac ttgagcgctt ataatctaga
    12661 ttccaatgct ttaggttttt attagatgta gaaaagccaa agctaacaat caggctgtct
    12721 agctcaagcg ttatctcctc ttctgacttt accttttgaa tagtcatttt gttgacaaag
    12781 ccattttctc cttcgagggc aaggggaaca aagggggtaa gggtagtaac atgagagttt
    12841 tttaacaatt ctacgctatg ctcatgagcc ctaaaggcgt ctcgccggtg cacaagggta
    12901 acactcttag cgaggccatc taaggctaaa gcccagtcca cagcagaatc tccaccaccg
    12961 cagatcacaa ccctcttacc agcaaactga ttcaagctgt gaacattata aaagagatta
    13021 tgatcagcaa ataactgctc attgtctaag cccaaggttc taggcgcaaa ggctccattg
    13081 ccacaagcaa caataatggc cttagaataa tgtctggcct tgcttgtttg aataacaaag
    13141 ttcccatcag ccttctcaaa agacaggacc tcttctttca ggcatactgc tatgcgatcg
    13201 tcaaatctgc ttagctgctc aataagcttt tgtgttagtt ccgctccagt cagggccgga
    13261 taagctggaa tatcatagat aaccttttca ggataaagaa cagccggctg tcctcctagc
    13321 tctgacaggc tttcaataat cttaaccgtc atgccgcgca ggcctgcata aaaggctgca
    13381 aataagccta ccggacctcc accaatgatg gtaatgtcat atattttttc ttgcactagt
    13441 tctctccttc acttagcccc gatttgattt tatcaaaaat ccttttttcc tcatcagaaa
    13501 aatcataagt ctctaataaa tctggtcttc tcaaataggt cttctttagg ctttgctcca
    13561 tacgccagag acgaatatgc tcatgatggc cactcattag gacatcaggc accttcatgc
    13621 cacgataatc atatggcctt gtatactgtg ggtactccaa gagcccagat gagaaggaat
    13681 cctcttgatg actggcttgc tttccaagca cattaggaat cagtctcact gttgcatcaa
    13741 tcattgtcat agcagccagc tcaccaccag ttaagacaaa atctcccaga gatatttcat
    13801 cggtaacaag tgtcttaatg cgttcgtcat agccttcgta atgcccacaa ataaaaatta
    13861 actcttcctc aagagctaat tcttcagcat aagactgatg aaagggtttt ccagcaggat
    13921 ccagtaaaat cactcgaggc tttgtagcct gaatgctatc catggtatca aaaataggct
    13981 gcgctctcag cagcatgccc tgcccaccac catatggctc atcatcaaca tgcctagctt
    14041 tctccgcatg gtcacgaaaa ttgtggtaat gaatatctaa aagccccttt tccttagcct
    14101 ttccaacaat ggagtgctcc aaaggagcaa acatttccgg gaaaagggtt aaaatatcaa
    14161 tcttcatcat ctaagccttc cataatttca acgtctaccc gatgcttttc gatatcaaca
    14221 caaagaacaa ccgatgggat ataaggaagc aacaggtcac gcttgctttg ccgtttgacc
    14281 acccaaacat catttgcacc aggctgtaaa atttccttaa tctctcctac tagctggtcc
    14341 ttttcataca cctccagacc aataatctgg tgatagtaaa attctccctc agctagctta
    14401 ccctgattct ctttagcaat cttaagactg tagcccttaa attgctcaat agcattgatg
    14461 tgatacattc ccttaaactt gataatgtca aactgcttat gcttgcgatg actcgcaatc
    14521 tcaacctcct gcacaaaacg atccttgtcg tcaaacaggg ctagtctagc acctttttga
    14581 aatcgttcct cagtaaagtc actcacagac agcacgcgca tttctccttg caagccttga
    14641 gtattgacaa tcttcccaac gctaaaatat tccatcctta ctcctaatca tcttagactc
    14701 tatagcttga tagacctcta ttttttcatg acaacacgac atgagtatca tcatcctaag
    14761 cactctagcc tatcgttaaa gctcccctta ttgtaacatg ttctgcctta ttttgcactt
    14821 ctctttcaaa aaattaatct cccagttata gcagctaagc ctagcaagca aagcccttga
    14881 tgctaaagaa tcctgatccc cctataatta acaaatcatc atgacttgcc ttgcccaagc
    14941 tcagtcaagt gaatgaaaaa tctgctaaac aatagccttg cgcctcgctg acaagcatca
    15001 aaaaaacact cctgctggca atctgaactg ccccccaatt gttagatttt atgtccaact
    15061 tttgggggtc agtacaatct agtaaactag aatcaggagt gtttcattat agcccaacaa
    15121 gcaaaaggaa tacttggtaa aagcaaagct gacttgcatt gagaagatta aaaccattca
    15181 atctgtcaca ataattatgg aaacattggg aatttaaaaa caagtatcag ctgctatcaa
    15241 cctgtgggga aatagtctac ctatgcctat cgggccatcc atcataggtc ctctcaagaa
    15301 atgatgagag cctcatcaac cagctatcat cgccttaaag gagaatgacg aatgttatcg
    15361 taggtgtccc aagaaatact acaaaagaaa ctcattttga tcttaatgct ctaaagggct
    15421 tgaccttacg tcaactgata aagctctact tcatagcatc gttttgcttt gcagcttttc
    15481 tatacctcat gtctaataaa agacataagc ttgccgataa gaacattacc ccaacataga
    15541 agaatagatt ggtctcatcg ccagtcttta gtaagatggt attttgatgc ttcatcggtt
    15601 tggtagctgt tgaaacatgc ggacacttgg tttcatttgt cgtcgatggt attgtcggac
    15661 gacttggctt agtgttatta ggcttatgat tgccttcact actgcttacc tttttcttcc
    15721 actgtgcaaa caattcatta ggaaacggca ggtcattatc taccctaatg tcatcaccta
    15781 ccttttttaa cctcctgctc gatctcttgt tgcatacaaa atgttataca gatacttctg
    15841 tcagatagag ttcttgcttt tgtctcttga cttggtgatt caaaacacaa aaaaagcctg
    15901 ctagatagaa ctagcaaggc tttaagatta gtcttgttca aaatagaact tatttttcat
    15961 caatgactaa tcgaaccttt tttcctaaag ttggcaccga atagacaatc gatcttatcg
    16021 ctgtgatggt acgacctttc tttccgataa cacgaccgat gtcttgagca tccaagtcaa
    16081 gatggtactc taaaaaatcc ggagtatctt caattttaat agtaagctta tctggttgtg
    16141 aaatcaaggg cttcacaata gcgataatga gattttcaat ggtatccata ggcttttatt
    16201 acttagaaaa tttttgatcg tggaatttag ccataacccc agctttagat agaaggctac
    16261 gaactgtatc agaaggttgt gcaccttttc ctagccaatc aagaacacga tcttctttaa
    16321 gagttacttg attttcagct acaagtgggt tgtaggttcc aactgtttcg atgaaacgac
    16381 catcacgtgg tgcacgtgaa tctgcaacgt tgatacggta gaaaggtttt ttcttagaac
    16441 ccatacgagt taaacggatt tttactgcca ttttaatatg tctcttttct ttaaatgata
    16501 atagtcaaga aatgtagtcc tgctcatttc tcacctaact agtatacttt acttttgatt
    16561 atgtgtcaag tttttttctt gacacttttt tatgatcata atactactca acatcttcaa
    16621 tcagctaagc tgcttagatg acatcaaaca gcaggcagct gctcttataa gagcatacaa
    16681 ctccaaacta acctactcta gtgatcctta gccgtcaata atgggatcag gcaagcataa
    16741 ctccccgtca aaggagcggt ttgtttcaca gcaaaaaggc gaaataaact gacaatcaca
    16801 tcaaaaagga cgagccccta aacatgcagg agctcgtcct tttaccaata tgacttagtc
    16861 tctccttgct tttaaggcta gggtattagc taagcgttac actaataatg catcaaaata
    16921 tgcttaagaa actctccacc ataaatccaa aaataactga aggtcaaaat tgaaatgggt
    16981 ctacaaatta ggataatcag taaaaagcgc ttgtaggtca tctgactcaa tccagtaatc
    17041 ataataagag catcggcagg ggctaagggg gaaatcatat tgagaataaa gaaacgctca
    17101 aataatttcg ttgatagctt cttttcataa aactgtagct gctccatact taaaaacagt
    17161 aagataaagg gctttccgta tctcctcacc aactgaaaca aaatagaaga tccaatgcag
    17221 ataccaaaca catttaacat aaagcctaat ataggaccaa aggctagaaa gccaacgact
    17281 gttgtcacac caccaggaat gataggaaca actacctgca caatttgcaa gataaaaaag
    17341 caaatggcac cgataaggag atgatccttg attaaatggg ctaaagcctt tggattatta
    17401 ataatatcta gctgcctaat aaggtagaca acaagcatga cggagaacag aattgatagg
    17461 ccaccaagaa tcttaaacag cttctttaac aacgaatgtg aaacaccaaa gctactcata
    17521 gcgcaaagcc tctatcggat caagcttgct tgctttgttt gctggcagca atccaaaaat
    17581 aataccaatt gatgccgaaa agataatagc tacagccgca acatctaagg aaacagctgc
    17641 tccctttaat tgcatcgcat ttcctagcac acctacacac atctgtgcta gcagcagccc
    17701 taaaagaccg ccaattaacg tcaacaccac tgattcaatc aaaaattggc taagtatctt
    17761 caagcgcgtt gctcccaagg cttttcgcaa gccaatttca cgtgtacgct ctgttacaga
    17821 taccagcatg atgttcataa caccaatacc acccacaaga agggaaattc ctgcaatgga
    17881 cccaacaact gtggtcatga tactaaattg tgcgttaatg tcattgataa tttggctatt
    17941 gtcaggaaca gcgtactcgc cctccttaac atgagacagt gtggtcagca tagcagctgc
    18001 ttgatttcct aattcaaggc ttcgcttaac gtcgccaata taaagataaa cagagccaat
    18061 ttccttgaca tgaaattctg aagccacctg ggtattggcc ataatggctc ctccagaaat
    18121 cccaccagca aacgaaacaa cctcctgatc agtcttgtaa acacctacta caaggtagtc
    18181 cttactatct agactaacca ccttatttag agcttgttca taattgcctt tgccaaataa
    18241 ttcgtcagcc aagacagtat ctaataggat aatgcgagaa aaatttttat aatccttgct
    18301 atttagcgtc ctacctgcaa caatatcata ttttttgact ttaaaataat cctgactaac
    18361 cccagtgatg gccacattgt ccatcttctt tttctcaaag gaaatggtag aggttgaatt
    18421 attggtatag taataagaat ctaccccatc aattgctttg acaatctgct ctagccattc
    18481 aggcttgacc tcttgctcat tttcatgcgc tgcaaaggcc gcgtaagggt tgtcctcatc
    18541 tccttttgcc ttgaaataaa gctgaacctc tttttggtca tttgaaaagg aatccgtaac
    18601 cctctttgtc atggcagcac caagccccat gataatcaca acagcagcta caccgataat
    18661 aattcccagc atggtaagaa tcgaacgcag cttgtgcccc cagattgaac taagagcaaa
    18721 tttccaattt tccatcactt ttcctcctag tcaatcctga cactttctgt tgtatcagct
    18781 gtgatttcac catcacgaat aacaattttt cgagtggcaa agtccgcaat ctctggctca
    18841 tgagtaacca taataatagt tttgccttcc ttattcagct ccgtcaaaag cctcataatc
    18901 tgctcaccag tctttgtatc tagggcacca gtcggctcat cagctaagat aatagacggg
    18961 ttattaacca aggctcttgc aatggcaacc ctttgctttt gaccacctga taactctgat
    19021 ggcaaatgct tcattcgcat accaagctca accttttcca aaaattgctt agccaattca
    19081 cgacgctttg atactccaac tccagcataa atcaagggaa gctcaacatt ttgcagggca
    19141 tttagctttg ctagtaaaaa gaactgctga aagacaaagc caatctcttc gtttctcacc
    19201 tgagcaagct ttcgatcatt taggatctca acctgtgtgc cattgagacg ataatcacct
    19261 gaggttggtc tatctaataa gccgatgata ttcatcaggg ttgatttccc tgagccagaa
    19321 ggccccataa tagcgacaaa ttcaccctca tatacagtca aatccacgcc ttttaggacc
    19381 tgtagctcct gatcaccatt ttgatagctt ttaacaatgc tttttaattg tattaattct
    19441 tttttctcat ctggcactac ttaatcacct cggattcttt actgcttttt ttagaatctt
    19501 ttgatgcctt tgtgtctgcg gaaataacgt cttctagctt ttcaccctct ttgatgttct
    19561 tatcagggtt agcaatgaca atatctccca cctttagacc tgcacttact tcttgtcttt
    19621 cagcatcagc attgcctagg gttacttcaa cctttttagc ctttgcagtt gagtcatcat
    19681 agacccagac aaaatgcttc ttgcctttgt taacgatagc agtaactggt actaaggcat
    19741 gctttgcttc gttgataacc tcaacagaca ccgtaaagcc ttgctttagc tggttaagcg
    19801 gactcgtgat atcaattttg tagtcatagg tcgcaccagt tgagcttgat gagcctgagc
    19861 ctcctgcagt tgaaccacct gcattggcat cggttgggta gtttgacaca taagaaatct
    19921 ttccggtcca ctcttgatca gcatagacct ttgatttaat cttcacagct tgtccaacct
    19981 taatattggc taaatcatac tctgttaggg tccctttgac ctgtaacttg ccttcggttg
    20041 cgacatgaac caaggtttga ctgttttttg aagacgggtc aatatcatta ttaacctcta
    20101 caactgtccc tgaaacacca ctgacaacta ctgtttcatt taaggcctgc tgtgctttat
    20161 tgacctctgc ttgagcatca gcataggaat catttaaatc ctgcaattgc tgagcatagc
    20221 tagcattttg ctgggctgag ggctgaatgg ttgtggtggt ttcttgccct gtctcctcgt
    20281 ccttgcttgt ctcagtagtt gctgctggaa caccatacgt ttttaaatga ttaatctgac
    20341 gcccaatttt attgagattg cgaacagcgg tgtcataagc tgcctgtggt acagttgtat
    20401 tgtactgtac taactgctgg ccttgtgtga cctgatctcc taccttaacc gtaacggtag
    20461 cgtctgagcc tttgctagca tcaaaataaa catattcttc tgaaagagct ttaacagtac
    20521 cagagagtaa ggttgaagag gctattgtcc cttctgttac atttaccgca gaataaggta
    20581 gcttgatatt ttgatcagag atagtatctt gctgttgctt ccacaatact ccaccgataa
    20641 cgactacagt tagtgcaact gcacctgcga taatgccttt ggttttcgtt gataacttta
    20701 tctttcctct tttagacatt tctgtcctcc ccttttgtac tatttttgta agacaagtat
    20761 atgatgtttt taaaaacttg tcaagaattt cttggataag cttaataaag cagcctcttc
    20821 atcatgtaga tgacaactct attataatgg tttttcaagc tgtactagct tacacttttg
    20881 taatattaaa aagaggcaaa gacaaaaaga gttgtccttt aactttatta cacagtctca
    20941 ttcattaaaa agcgaacaag cctagttttc aaaatctcag aaaactagac ttgttcgttt
    21001 gtttagactt ttctctcagt ctcttcatca ggtttaaata gcttctatac taaaggtacg
    21061 gctttcaaga actctcagca ttgctactgc tgtatccaat gctgtaaaca gaggaactcc
    21121 ttgttcgatt gctgagcttc tgatcatctg cccgtcctta tcagtcactc gttttgttcc
    21181 tacggtatta ataatagctt gaatctgccc ttttctcagt aaggctggga tatcatgagc
    21241 attgtcgcca atttttccaa ctagctgtga atctagccct tggtcagcaa agaaagcagc
    21301 tgtgccttcg gttgccatga tctggtagcc aatagcacta aagcgtctag ctaagatcag
    21361 agcctccgac ttatggtcat cagcgatggt aaaaactatt gttccatatt ccggcatgtg
    21421 cagatagcta gcttcaaagg ctttgtaaag ggctttttca agtgttaaat cagagcccat
    21481 gacttcacca gttgatttca tctcaggccc taaaaggcta tccaccttag cgagctttgc
    21541 aaatgaaaaa accggtgcct tgatatgaac aagcgagctt tcaggataaa ggccatcttg
    21601 ataacctaag tcttttaagg tctgacccag aataagcttc gtagcgactt gtgccattgg
    21661 aatattggtt acttttgata aaaatggcac tgtccgactg gcacgaggat tgacctcaat
    21721 gacatagacc tgctcatttt ggatcacaaa ttggatattc atcatgccaa tacagtttag
    21781 ccctatagca agacgcttag tgtaatcaac aatcttgtct tgaacctgtt tagataggtg
    21841 ctgcggcggg tacacagcca ttgaatctcc tgaatgcact cctgctcttt cgatatgctc
    21901 catgatccct gggattaaga ctgattgacc gtcagagatt gcatctacct cgcattcctt
    21961 accaaggata taagaatcta ttaaaacagg atgctcagga ctagccttga cagctgtttt
    22021 catgtaggag cgtaaatcgt tttcattttc aacaatttcc attgctcggc caccaagaac
    22081 ataagagggt ctgaccaata ccggaaagcc aatggcacgc gctgcctcta aggcctctgc
    22141 ctcattggtg gctgttttcc caggaggctg agggatcccc agctccttca aggctttttc
    22201 aaaaagctcc ctatcctcag cacaatctaa gtcctctagc tgtgtgccta aaataggaac
    22261 tccggccttg gttaactgct ctgctagatt aatagcagtt tgtccaccaa actgtaggat
    22321 tactcccttt ggctgctcta attcaataac gttcatgacc tcttcaaagg ttaagggttc
    22381 aaaataaagc ttgtctgata tcgaaaaatc tgttgacact gtttcaggat ttgaattcat
    22441 gataatggct tcatagcccg cagcctgaat agccttgaca gaatgtacgg ttgcataatc
    22501 aaactcaact ccctgaccga tgcggatagg accagagcca aggacgataa cagattcttt
    22561 ctcggatttg attgattcgt tttcccactc ataggtcgag taaaaataag gcgtttgtga
    22621 gtcaaattca gctgcacagg tatcaaccat cttataaact ggcaagacac gataggctcg
    22681 ccttaaccgt ctaatacttg cagcatcagt ttgccaaagc tctgcaattt tttggtctga
    22741 aaaaccatat cgcttggctt ctatcagcaa atcgatatca actggctttt taataaggtc
    22801 ttgctccagt tctacgatat gacgtaattt atccaaaaag aataaatcaa tcttggttaa
    22861 gccagctagc tcttcaatac tatagccacg acgaagggcc tcagaaagat agaatagacg
    22921 atcgtcctgt gctcttacaa tgtgagcaac cagctcatga tcactgatag tatctagacc
    22981 cttcagttcg ttatggtgta ctccaatttc caacgagcga caagccttta agagacattc
    23041 ctcaatacgg cgtccaatag ccataacctc accagttgct ttcatctggg ttcctagacg
    23101 acgctccccc cgctcaaact tgtcaaatgg aaagcgtggc agcttggcaa ccacataatc
    23161 aagagctggt tcaaacatgg cataggtggt tcctgtgacc ggattaagca tgtcatcaag
    23221 ccttaagcca actgcaattt tagcagctat tttagcgatt ggataaccag ttgcctttga
    23281 agccagtgct gatgagcgag atacccgcgg attaacctca atcacataat agctgaagct
    23341 attgggatca agtgccagct gaacattaca gcctccttca atcttaaggg cacgaataat
    23401 tctcaagcta gcatcacgaa gcagctgatt ctcaacatct gatagggttt gtgtcggggc
    23461 aaaaacgatt gaatctccag tatgtatccc tactgggtca aaattttcca tactgcaaac
    23521 aaccagcgcg ttatcagcag catcacgcat gacctcatat tcaatctctt taaagccggc
    23581 aatggagcgt tcaatcagac actgggtgac aggagatagc ttcaggccat tctccacaat
    23641 atctcgcaag acctcttcat tggagcaaat accacctcca gtgcctccca gagtaaaggc
    23701 ggggcggaca ataacagggt agccaatggc atttgcaaag ccgatagccg cctctactgt
    23761 cgtcacaatc tctgattctg gaataggctc tcccaactct ttcattaatt gcttaaataa
    23821 atcacgatcc tctgcctgat caatagcaga taaggttgtt ccaagcagct ccactcctaa
    23881 ttcttgtaaa ataccagcct tagacagttc catcgccatg ttaagaccgg tctgcccacc
    23941 taaggtcggc agcaaggcgt ctggtctttc ctttcttaag atacgactaa caaatgccaa
    24001 cgtcaggggc tcgatataaa ccttatctgc aacctctttg tctgtcataa ttgtcgcagg
    24061 gttagaatta accagaacaa cctgatagcc ctcttccttt aaggctaaac aagcctgtgt
    24121 tcctgcgtaa tcaaattcag ctgcctgccc aataacaata ggaccagacc ctatcaccat
    24181 gattttttta atatctgtac gttttgccat aatatctggt acaaaaggcc ttaacaatcc
    24241 gaataaaata atgcaagcac ctaacattaa agcatcacaa tctatttttt actaggattt
    24301 gtacctgtac tcagctgcag caagcccttt gtacctactc ctttcattat ttgccgtctc
    24361 acagggcggc attaaataaa acacttaaca gtctgtcaca tgagacgatg agtacaagat
    24421 caagtaaccc ttagctcagc aagtatagat gacttaattg atatagtctt tttacttcta
    24481 aagagggcga tcttgccagc aaatactagt cataacccgc ggcagagcga tcatttccca
    24541 ctagtctatc tgctgcctga ctcaagctgt ttcatgacag ctgatcaagc ctttggtgct
    24601 tgctttttga tctgctagca cacttgatta acatttgcct tgctgctcta gctgccaggc
    24661 gtcaatcata tctaaaaatt catcaaatag atagctagcg tcatgagggc ctggtgcagc
    24721 gtctgggtga aactgcacag aaaaggcggg aacatgtcga tgtctcaccc cttcaacagt
    24781 tttgtcatta atctcctcgt gcgtaaccat caagcagtct ggcaagctgt cgcgctcaac
    24841 agcataacca tgattttgac tagtaaaatc aatacgtccg gtcgctattt ctctgacagc
    24901 atgattaaag ccacgatgtc caaaaggcat tttaaaggtc ttagcgccat tagctaagct
    24961 aagcagctga tggcccatac aaatgccaaa aattggaatt tttccttgaa caccacgaat
    25021 catctccaag gcctccggca aatcctctgg attacctgga ccatttgata gcattagacc
    25081 atctgggttg agctgtagaa tctcttctgc tgtgatatca aaggggacta ttgtcatctg
    25141 acattgcctt ttggataatt ctcttaaaat ggaatgcttc aagccaaagt ccaccaaaac
    25201 aatatttttc ccaacacccg gagcgggata ggcagtctta gttgacacct gctcaatacc
    25261 attagtcgga agcacagttg cacgcagctg atcctttagg tgttcaagcg tatcaccatc
    25321 atctgccatt gttgccttca tcgtaccatg ctgacgaatg attttggtca acgctctggt
    25381 atcaattcct gaaatgcctg gaatcccctt atgctttaaa aactcgtcca aggtcatttg
    25441 ctgacgccaa ttgctagcta tcctgcttac ttcagagaca atgacccctt tgcaagttgg
    25501 ggcaatggac tcataatcat cacgattaat accataatta ccaacaaggg gataggtaaa
    25561 tactaagagc tgcccgttat aggactggtc tgtgattgac tcctggtagc ctgtcattcc
    25621 tgtattaaag acaatctcgc cagtgacatc aatatctgca ccaaagggct ttccttcaaa
    25681 aatggtgcca tcctctaaga taagtaaccg ttttgccatt ttaaccccct ctaacatgcc
    25741 tttagacctt atcgtttctg ccattaagga tcgcttcgat aatggccata cggacaaata
    25801 caccattagc catttgagct actattcttg cctttggagc ctctactaaa tggtcagcaa
    25861 tctcaacatc gcgattaacc ggtgccgggt gcataataat cgcagagtcc tttaaccgcc
    25921 tgtagcgctc ctcagttaga ccaaactgtc tatgataatc ttccttggaa aagctttgac
    25981 taccatcatg gcgctcatgc tgcaccctaa gcagcatcaa cacatctaat tgatcaataa
    26041 tgtgatcaat cgccatgtac cttccatagc tgtcaaattc agacgagtac cattgctcag
    26101 gaccatagaa ataaagctct gctccaagcc gctttagaat ctgcatgttt gatttagcca
    26161 cacgagaatg tgtcaaatcc cctgcaatag caatcttcag gccatcaaaa tgaccaaatt
    26221 cttcataaat agttagcaaa tcaagcaagc attgactagg gtgctgacct gatccatcac
    26281 ctccattaac gatagaggca gtaatcgttg gactgtcaat aagctgctga tagtaatcat
    26341 cttctgggtg acgaatcacg cagatttctg ttcctagagc actcatggta agaacagtat
    26401 catataaggt ttccccttta ttgacagcac ttgtatcagc gttaaaatca aggactctaa
    26461 gaccaagctt gttctcagca acctcaaagg atttatgggt tcttgttgaa ttttcaaaga
    26521 ataaattagc tgcaaagtgc ctactgttat ctttaatagc taccttacct gccttgtatt
    26581 cagagccacg actaataagt cctaaaacct cttcatttgt taaatgctcc attgacacca
    26641 aatgcttaag cgcaacacga ttatttacaa ctgacatgat ttatcccctt ttaccaataa
    26701 tgaaatgatg ataacaattg acaacagcta cacactagtt ttctggaaga agctgataca
    26761 atataatgcc aagaagcgtt gaaaaagcaa cacccgaaat ctgaaggcca ttgatttgaa
    26821 gcatgaggcc tccaatacca gaaaccagaa taacactagc aatcaatagg tttttcttgt
    26881 tgtccatatc aaccttagct tcaatcagga ttttcaagcc actagaggct ataaccccaa
    26941 acagagcaat cgaaatccct ccaatcactg gagtaggaat agactgaata agtgctgata
    27001 ccttaccaac aaagcttaac aaaccagcaa tcacagcggc acctgcaata acatagactg
    27061 agaagatttt attgagggcc atcacaccaa tattttcacc ataagatgtt accggaggcg
    27121 ctcctaaaaa tccagcaatc acctgtgcaa ggccatcacc cgtcaaggtt ttttccaagc
    27181 caggatcctt gaaataatct cttttagtca ggctattaag caccatgata tgaccgaaat
    27241 gctctgtcat ggtgacaaag gcaatcgggg ccatcgttaa aatagcacta ggatacaagg
    27301 taatgtcata ggttaaaaag gggatagcca cagctggaac actgagccat tgggccttag
    27361 caacctgtgt aaagtcaaca atagactgac ccgtcaccat accaacaagg atcgcaaaca
    27421 aatagccaac caataagccc aacaaaatag gaatgatggc gacaatccct ttaccataaa
    27481 tgttaaagaa aataatcgct aataaggtga caagaccaat caaaaggtat aacaggttat
    27541 actttccatc ctttagcatg acatcactaa ctgctgttga ggccaagcta agaccgatca
    27601 ccataacaat gggaccaacc acaactggag gtaagatctt atcgatccat tcattgccaa
    27661 tcgccttcac caccagtgct acaaccagat aaaccaggcc acctgtaatc gctccctgtg
    27721 caactgcacc aataccatct gttttcatta gcatttgcat ggctgcaata taagcaaagc
    27781 ttgagcccat ataagcggga attttaaatg ttgttactga caaatgcgcc agagtcccaa
    27841 gtccacttga taagagggca actgacggat caatcccaac caaaattgga accaaaacag
    27901 ttgctccaaa catagcaaat aaatgctgga aggacaagcc aagcaaaatc cctgcctttg
    27961 gcacttcttc tacatcataa atgacatctt tcacacaatc acctctttct tatcccggat
    28021 caacaatact aatacgatct tgaccgtcaa cctcaaccac ctcaacgaca atctcttctg
    28081 tcttgcttgt gggaatattc tttccaacat aatcggcccg aattggtaat tcacgatggc
    28141 ctcgatccac caaaacagct aggctaacac gtccaggacg ccctaagcta accaaattgt
    28201 cgatagctgc ccgaatcgtt ctgccggtat aaagcacgtc atctactaag ataatatcct
    28261 tgccggtaat atctaccggc atgctggtgg tgtcctcttc cactctcata tcatctctaa
    28321 agggcttggt atctagctct ccaactgcca agtgcaggct ttctagctgc tctaatcttt
    28381 cttgaatacg acgagcaagg taaacacctc ttgttttaat ccctacaagc accacattgt
    28441 ctagttgctt gttgcgctca ataatctcgt acgtaatccg cgtgatcgca cgcttcatgg
    28501 ttagctcatc aacaattacc tttgatttca ttcaaagcct cctcaaaaaa ttcaactaaa
    28561 aaaatctccc tgttaacaag gagattcagc aaaacaggca cacagctaga cataactgtg
    28621 cactttttta ttcagaacat gctccttgcc agcctcacag gactgtttta aaggaatatt
    28681 ttattttcat tagtatagca aaatcacaag ccaaaaacaa ggattttcta aaaaataatt
    28741 caaaatatat agagctatca cagcaccaag gaaaatgcta ctaaggtcat cagcaatcct
    28801 ccaacacaat tccaaaaata ggtcttaaga cctattgtat ttgtatcaaa acaatagcac
    28861 aataatatca aacacaaagg agagcgttta tgatgaatga tataactaga aagattaacc
    28921 ataagcaact gattcaaatc actaccattc taggcattat tgttaccatc gttattttgt
    28981 tctatctgca gcagcaccct aatctttttg cagttggcgg tccttttcag acctatctta
    29041 tggaacttgg tatcctagca ccctgtttgt ttatactgct tcaaatcatt caagtggttt
    29101 accctatcat tcctggaggc ttgacctgtg ttttagggca tgtagtcttt gggccgtttt
    29161 ggggatttct ttataatact ctaggtattt ttattggttc gctgcttagc tttatgctcg
    29221 ctagaaaata tggtgaacag tttgctaaag cctttgtatc agatgatacc tataacaaat
    29281 acattcctta cctcaataaa ggcaagtact ttgaacgatt tctcataaca gcctttattc
    29341 tccctggctt tccagatgat tttctctgta tggtagctgg actaagcagc atgtctatca
    29401 aaacatttac cagtattttc ttgatatcaa agccaattac tctttatatc tacacccttc
    29461 ttgcttacca aggcatacaa atcgttggac aggtattgca atcctaaaaa aagctagtat
    29521 taagctatca agcctgattg gaatacagta ttccaatcaa aaaggcgctc agcttggtac
    29581 cagcttttta tccttgtctt agttgctcca aagtcctttg gaagatttct ggtggctcaa
    29641 cagtaaagac cagctcctct cctgtcacag ggtgggttag tcccaatgtt tgcgcatgaa
    29701 gaaactgccc cttgccagcc aaggtcttac gaggaccgta gagtggatct cctgcaagag
    29761 ggtgaccaat ataagccata tgaacgcgaa tttgatgcgt tcgacctgtt tccaattgta
    29821 attccacgaa ggtatagtgg ccaaagcgct ccaaaacctt aaaaagagtc aaggcttcct
    29881 tgcccttagc agttacggtc tgttttttac gatccttttc actgcggcca atcggagctt
    29941 caattacacc tcgatccttt ggtaaattac catgaacaat ggccacatac tttcgtaagg
    30001 atttcttagc cttgagctca tcagctagta gctggtgggc cttatcggtc ttggcaacca
    30061 ttaaaagacc agaggtatcc ttatcaattc tatgcacaat tcctggacga ataacaccat
    30121 taatagaaga caggtctttg atatgataga gcaaggcatt gaccagcgtc cctgtagaat
    30181 gccccgcaga agggtgaaca accattccct gaggcttatt aataatggcc aatacatcat
    30241 cttggtagac aatatctagt ggtatatcct gagcctgata gtccaagctg ctttcctctg
    30301 ggatatgata gctaatgcag tcacccacct gcacaatata cttggccttc ttaggtaagc
    30361 cattgaccaa tacccttttt tgcttgatct gatcattagc ctgacttctt gataatgggg
    30421 tcaaatcagc caaggcctta tccaagcgat ggcctgattc tgttatctta atttccatag
    30481 tcctcttctt tccatagaca aatgaccagc agcaaaacac ctatcgtcaa ataggaatct
    30541 gccacattaa aaatagcaaa attgatcaca tctaaatgaa tcatatcaac cacataggat
    30601 aacctcaagc ggtcaataaa attcccaaga cctccagata taatcagcaa taaagagagc
    30661 tgtagccaaa agctagcctt tgggtgcttc aacacataat aaatggcata gccaaccacc
    30721 aaaacagtta tgattgtaaa gaaccactgc tgattctgta gtatggaaaa agcagctcct
    30781 cgattttgaa gataggtcaa gctcaccaaa cctggtataa agggcttcac ctgccctagc
    30841 tcaatatgtg taacagtcca ccatttactt agctgatcca gtatcattaa gacaatggca
    30901 gccataataa aactaattct tttcaactaa tcctattcct ttcagcttaa aaacaagaga
    30961 ttaccttgat ggcttcaaaa aagcaacaac agccagctgt ctctgtagcg tactcaacct
    31021 taaagcctcc aaaaactggt attctagtaa ccttttagta tcattgatag tcaaccacac
    31081 agcagctcta gacttgactt tatatcaaca agtctcacca cagcagctcg cttaatcctt
    31141 atccatacca gagctaagtc ccattgtcta tagcttgctt ttcttttcga tgttcaaaat
    31201 aatcctgtaa aatggtcaca aaatgtaaag ccgcagcaga taggttctta tccctacgct
    31261 tgacataaat cattttatgc tccatatgat cacgcaaggg aataaccttg atgccattaa
    31321 cgctttgctg atctaaaaat ccagaccctg ttgcaaaggc agctgtcctt tccaaaatgc
    31381 catttaaggt tgccctatct gacacagtgt atatgtgagg actcttgctt gtgtcaataa
    31441 aattttctga ataataaaga tattcttctt tttcttgagt aaagcgtacc gctggcagcc
    31501 cttgcaaatc ctctaagaaa agggctttcc tttgagccaa tggatggttt tttgataggt
    31561 aaatatgggt tgtaaaggat agcaattcaa cataatccaa agccagctta tccattcgct
    31621 gaaaaagccc ctgacggttt tgtgcattaa gatagataat tccaagctca ctatttccct
    31681 gtgccacctc atctaaaatt tgcatagtcg ttgactcaaa aactctaaaa accttatgcc
    31741 cagcatgctt ttgggaaaat gctgttatta aagctggtaa aaaatcataa tgctgactcg
    31801 caattgaaaa ttcatttggc tccaaagccg attgagaaaa ctccttttcc agcgagtcaa
    31861 agcacttaac aacctctaag gccttttcat aaaataaaag cccctggctg gttaacacag
    31921 ttcctgctgt tgtcctacga aagatctgaa agccaagctc tgtctccaaa tccttcactg
    31981 aaacagacaa actgggttga ctgacaaata gctttgaagc agcctcacga aaggtaccat
    32041 tatttgcaat agcaaccaca tatcgtaatt gttgaatatt cattaatcca cttcctaaat
    32101 ctagtaccct tcattatacc ataaagccag ccaatgaaaa ataaaggcgt ccatcttaac
    32161 catgccaaac gtatctacag ataatcatga gatagcattg actttttcaa tagtgtctta
    32221 tcatatttag ctatagaaaa cagccttact ataagttata cttttgaaag aagtaagcct
    32281 tagatcacag aacatcacac tgagattttt tatgcgctta tcctgtctgt ccaagaactg
    32341 agaattggct acatctagct aataagccat ttcaggattt tactgtctag gagttattta
    32401 taggcaacta ttacagtaag atagtgtcac aatacaaaaa aggctatccc aaagtacaga
    32461 acagccttat accgtgccct tttaacacat tattttgcga ttgggtatac agaaacttgt
    32521 ttcttatcgc gtcccttacg ctcaaagcgt acaacacctt caaccttagc aaaaagagta
    32581 tcatctccgc cacgaccaac gttaacacca ggataaatat gtgtgccgcg ttgacggtaa
    32641 aggattgaac ctcctgaaac tgtttgtcca tcagctgcct tagcgccaag acgttttgct
    32701 tgtgaatcac gtccgttaga agttgaacct ccaccttttt tgtgggcgaa gtgttgtagg
    32761 ttagaaagat taagtttaat catttttatt tcctctcgtt gaatttaatt catcacaggc
    32821 ttttgaacat attctgataa atgctctgcc aaattctcca agccaatcac aacagactca
    32881 aacagaattt gccacacctg ctcttgttgc tcagtaaatc cctcaggctt tgttaccctt
    32941 aggaatccac caccatcgac catttctagt gctggctcaa gacctgtcat ctgttcaact
    33001 gaattaacaa gattgaaggc caaaactgaa accgaagcac aaactacatc aaagccgtac
    33061 tcaccgcttc cagcatgtcc tgtgataagc atctcagtcc agccagctgc gtcttttgtt
    33121 aaccgtactt taatcatgtc aaactagaat tatgccttga tagcgttaat cacaacttta
    33181 gtgtaaggct gacgatgacc ttgcttacgg tggctacctt ttttaggctt gtacttaaag
    33241 gttacaacct tcttttgttt tccttgcttt tcaacagttc caacgacagt agctccctca
    33301 acaactggag taccaacgac agtcttatca ccacctacga gaacaacctc gttaaaagtg
    33361 atttctgcgc cagcttcagc gtcaattttc tcaacgtaga ttgcttgacc tacttcaact
    33421 ttaacctgtt ttccaccagt tttgatgatt gcatatgtgc tcatgatgca cctcctataa
    33481 gatttttgat gaggtttccc tctgtgaaga ctcgcctaga atcgtgagag ccaatctact
    33541 tgaaaacgat tttcgtgcgg ttgcacagga cgtgcactta gtcaacgtta caattttaac
    33601 atcaaatttg atttttatca agaaaaatat gcttttatct tcctaaaatc ttaagctata
    33661 cataatcaca gctatgtaaa ggctagcaat gctttaccat tttaggttaa ccagggcatt
    33721 catttcttta taagcaatag ctgctttttc ttgcgtttcg ggatcaatct tatcataata
    33781 tctgccgcct ttgataaagt cctccaaaac catggtacga tagctatata gctcatagcc
    33841 ttcactacca taaaggccct taggcttagc taaaaccatt gtcgggtgag cctttactgt
    33901 ttttattttt gttttttgcc ccttcttctc aaaggtaagg tccattagca cgccgcgctc
    33961 tgtccaaata tcatcaacag tctctaggcg ttgattggaa atgaaattac ccattgaata
    34021 gataataaat ttcttttcct tgtccttaac aatcgtctct gccggctcta cgacgtgggg
    34081 gtgacctcct aagacaacat cagcacccca gtcaatcatt tttcgataaa gagttttttg
    34141 ctcagctgtt ggctctaaag catactctgt gcccatctgc ggcataacaa tggtaatatc
    34201 ggcctctttt tcagcacgca agatgtcttt ttgtatcttt tcctcattaa ggtcagacag
    34261 gtgcttgtca tactcctcct gactgagtgt cgcctccatt ccattatagc catatgaata
    34321 gcccaatatt gcaatcttaa tcccattaac ctttttaatg agaatgttct ccttagagcg
    34381 atcctgctca taaataccaa tgctgtctat ccccatatca gcaaaaacac gcttggtatt
    34441 gagagctcct tctaatcttg agtccaaaat atggttatgg gccaaatcaa ccacatcata
    34501 gccagtatgc ttaagcgcag cagcaatagc ctctggcgca ttaaacaaag gatagccagc
    34561 tagaggatag tctggactga tcgttccctc atagtctcca atggccaaat cagcctgact
    34621 aatccaatcc ttcacatact caaaataggg attaaaatca tagctaccat cagccttttt
    34681 agcactcata tagagaatat catgaatcaa aatatcacca tttgcgacaa cacgcgctgt
    34741 ttgtgtcttt tgaggtgtct tgcttttcgt ttgtgtgcct ttttttgaca tgcctaataa
    34801 atcaaaggcc aacccaaaaa caagtatcac cacaatcaag gtaagcactg aaagcatggt
    34861 ctttttatac tgaaaatctt ttagcaagcg tcaaacctcc ttttttccta ttataccatg
    34921 ttgacacgac tttttaataa caaatcccaa agaaaaggct atgcccattt aagaagaatg
    34981 ccttagacag cagcatagac tcgtattagc tagtcaaaaa actagattgc tcctctttgg
    35041 ttgatgtcat atactttgag cctaaatagc tttcaacaaa gtctaatagt tgaataatgt
    35101 catgcaaaat atggtataat gaaacaaaat caaactagtc aggatagtca catgaagcat
    35161 aactctttca gccgctcact attactcccc cttctcatct gttccttgtc tgcttgctct
    35221 tctcatacag agaaaaaaga ccataccaaa gacgctactg ctatcaccga tacccgaaaa
    35281 gcagagcatc aggacatcag ggcaaatatg gaaaaggtca agctcgctac cgctagcacc
    35341 gacttcaaag gtggctcaag ccttgaggag ctaatcacta tttttggaca gcctagtcag
    35401 cacgaagaaa aagcagctgg tagtgttact cttgactcct acacatggca gtttgaccat
    35461 gtcacggtta atattaacct ctatgaaaac agcagcattg ttaaaactat tgctaacttt
    35521 gcttttatta gagacctgac cttatcctta aaggactaca acagcttgaa aaagggcatg
    35581 acctatgatg aggtcaagca gctattgact gagcctgata attacagtca agccaattcc
    35641 agtgaaaaag aaaccattca agccatttgg attagtggct taaaagctca gacacagggt
    35701 gccaatatag cactaacctt tgaaaacaac cagttgacag aaatgtcaca ggttggtctt
    35761 gaagactagt ttgtggataa ccccaatcat attaatgata gaaaaaagct tgatatttaa
    35821 taagatcaag ctcaaacgat agaccaagta gctgatgatc ttgacagtaa tgtgtaacaa
    35881 gctgagatac tactcactag gcagtattta ctagcagcca ctgaatttcc tttatgatga
    35941 caggcaacca ccttttttgt ggtgacctat caatagcacc ataagctctc ttttgtcaca
    36001 taccttgctt aacattattt taccaggtat gtgatgagct ttttaggttg tctgatagta
    36061 taacatctaa cccctagttg atgatgtaga taaggcaaga gctgctaagg atagcaccat
    36121 aaataagatc caacataggg tcatattata tagtgccaag aacgaaaaga taaagacacc
    36181 tacagggagc gataaagaga acagaagacc taaaaagtta ttgctttggg ctagcatatc
    36241 tgatgggaga ttttccatta aaagggcgtc cagcttgggt gtggcttttc ccataatata
    36301 agctgcaaag gctaagcata aaacccctat gatggcaggt aattgcagag cattagagac
    36361 tcctaccagc aaaaatgcta tgccctgagt ctgtactagc tttgatattg aaagccttga
    36421 aaagtaatcc tttggtgtta gatttcccaa catcgctccg ataatcgtaa cggcatcaac
    36481 aataactaaa gactgcccat aatgaaaatg aaatagctga tgatccatca aataaaaatg
    36541 ataaatgcta ttaattgctc ctccaatagc gtttaaggtc aagatggata agagtaacat
    36601 cacaaaagag atatgatcaa tctttttaaa ggtctctgtc atccttgtat acatcacctt
    36661 aaattgcttc attaatgaaa cacctgcttc agaagcttca acgacatcat gccttagctt
    36721 ttgtcgattt ttaagaagca caacagatga caataaaaag gaaatagcat ttatcaaagc
    36781 aacaaaggca taattgttgc ctgatgtcgt tagcagccaa actcctaaag cttgtcctgc
    36841 aatactagag aggtagccga taaattgagc aaaagaatag gcctcataga gcttttctga
    36901 ttcaatattt ttctgcatta tcgggagacg taagccattt ttgtaatcac ttagaatatc
    36961 agaaaccaca ttcaaaaagc ccacaaaggc aaataccaag aacgtctgat ttgtcatcaa
    37021 caaggctaca agcgtaaata aaagagattg tataaaacca ataacaataa gatttcttgt
    37081 tttccttttt gtcttatctg ctttgacgcc aatccaaaag gtaaacacca taggaatgat
    37141 ggtgatgata ttggctataa aaacagcaat atgagaataa ggtagcgtgg ttgcataaat
    37201 aataaaaaca atattgtaaa tataagagcc taaagcactt aaaaagtttg aaactgtcag
    37261 tgttctaaaa acgacatttt taatcaatcc cctcatttac ttacctgttg acgtcctttc
    37321 ttatgtcacc ttactttact tgattgaata tacttacagc atatctaaat tcgtactgta
    37381 gttttatatg gtgttctgac atgattttgc tactaattag taattcacaa gccttttcta
    37441 agtataaagt atcgtttgtt agtctaaata cttgtaaaag tgtcatggct atccccagca
    37501 ttccgttcca tagaccacta aactgagcaa attcaactaa taacgactcc gataaattct
    37561 taatatcttt aatatattta tcggagttaa cgtaaataag caattgaacg atcccagcag
    37621 tcccatttga taagtatgga gatacagaat tttctgatat taatacaccc cgatttccat
    37681 cgctatcttc aactaagctt tctagaataa aatcaattcc tttctcaata atttcgttat
    37741 cataagaaat tgaagacaga tagaacaata ctccagctaa accatttaac cctaaattaa
    37801 ct
//
LOCUS       DARYNN010000019        37386 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.019, whole genome shotgun sequence.
ACCESSION   DARYNN010000019 DARYNN010000000
VERSION     DARYNN010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37386)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37386)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37386
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.019"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            19..91
                     /locus_tag="TVB59_000860"
     tRNA            19..91
                     /locus_tag="TVB59_000860"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:52..54,aa:Asp,seq:gtc)
     gene            95..167
                     /locus_tag="TVB59_000861"
     tRNA            95..167
                     /locus_tag="TVB59_000861"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:128..130,aa:Lys,seq:ttt)
     gene            173..254
                     /locus_tag="TVB59_000862"
     tRNA            173..254
                     /locus_tag="TVB59_000862"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:207..209,aa:Leu,seq:tag)
     gene            262..334
                     /locus_tag="TVB59_000863"
     tRNA            262..334
                     /locus_tag="TVB59_000863"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:295..297,aa:Thr,seq:tgt)
     gene            346..417
                     /locus_tag="TVB59_000864"
     tRNA            346..417
                     /locus_tag="TVB59_000864"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:378..380,aa:Gly,seq:gcc)
     gene            426..510
                     /locus_tag="TVB59_000865"
     tRNA            426..510
                     /locus_tag="TVB59_000865"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:460..462,aa:Leu,seq:taa)
     gene            525..598
                     /locus_tag="TVB59_000866"
     tRNA            525..598
                     /locus_tag="TVB59_000866"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:559..561,aa:Arg,seq:acg)
     gene            605..678
                     /locus_tag="TVB59_000867"
     tRNA            605..678
                     /locus_tag="TVB59_000867"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:639..641,aa:Pro,seq:tgg)
     gene            689..762
                     /locus_tag="TVB59_000868"
     tRNA            689..762
                     /locus_tag="TVB59_000868"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:723..725,aa:Met,seq:cat)
     gene            783..856
                     /locus_tag="TVB59_000869"
     tRNA            783..856
                     /locus_tag="TVB59_000869"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:817..819,aa:Ile,seq:cat)
     gene            864..953
                     /locus_tag="TVB59_000870"
     tRNA            864..953
                     /locus_tag="TVB59_000870"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:900..902,aa:Ser,seq:tga)
     gene            965..1038
                     /locus_tag="TVB59_000871"
     tRNA            965..1038
                     /locus_tag="TVB59_000871"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:999..1001,aa:Met,seq:cat)
     gene            1063..1135
                     /locus_tag="TVB59_000872"
     tRNA            1063..1135
                     /locus_tag="TVB59_000872"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1096..1098,aa:Phe,seq:gaa)
     gene            1141..1211
                     /locus_tag="TVB59_000873"
     tRNA            1141..1211
                     /locus_tag="TVB59_000873"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1173..1175,aa:Gly,seq:tcc)
     gene            1241..1314
                     /locus_tag="TVB59_000874"
     tRNA            1241..1314
                     /locus_tag="TVB59_000874"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1275..1277,aa:Ile,seq:gat)
     gene            1324..1411
                     /locus_tag="TVB59_000875"
     tRNA            1324..1411
                     /locus_tag="TVB59_000875"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1358..1360,aa:Ser,seq:gct)
     gene            1470..2285
                     /locus_tag="TVB59_000876"
     CDS             1470..2285
                     /locus_tag="TVB59_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEL1009784.1"
                     /translation="MKKLNLSRLFFWLTSLALLALTLVLLFRVAISPYLSMIIRNPVT
                     KIDAIMSKPFAVIKEGAKELDSLMSAFSENKHLKKELRSYKLDQLQVDKLKSENRELK
                     ELLGLDYGTDNQFAARMISRNPYSWNKSLVIDSGKREIKEKSLVTSELGLIGRVTAVS
                     QSSAHVELLTSGKNIELPIKIVDKDKVIYGNLKAFKSESKTMVASEFNSNDSISLDAK
                     VYTSGLDGETVADIPVGKVTGFKNAADKLKRRIFIKLYADTDNLDYVLVVGKE"
     gene            2288..2791
                     /gene="mreD"
                     /locus_tag="TVB59_000877"
     CDS             2288..2791
                     /gene="mreD"
                     /locus_tag="TVB59_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEL1009785.1"
                     /translation="MKKSSELLVLLPFLLFFVDAHVSDLISSMLPEGYSVVSHLFLLF
                     FLILMVAFRSKGVICFFSLLLGLLFDYYYFDHIGILSLALPFGTMIVLGLLRFFSGSI
                     SQLQFFLFFTLYMFLVDVSSFILANSYQLTDMTFPYVMTFQLAPTLIVNLLILFCFRK
                     LILSQFY"
     gene            2887..4065
                     /locus_tag="TVB59_000878"
     CDS             2887..4065
                     /locus_tag="TVB59_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002996017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL1009786.1"
                     /translation="MKKRILSAVLVSGVTLGTATTVGADDLDSKIALQNSVISNLNKE
                     QKAAQDRMKTLQSQVSSLQSEQERLVAKNGELEARSAQFEQEIQVLASQIIARNEKLK
                     GQARSAQKGNTLGYLNALLNSKSISDVITRLVAINRAVSANAQMLEKQKADKLSLEEK
                     QQENQEAINTIASNITAIESNQVALKTQQADLEVAKVDLALQLATAEDEKASLITRKE
                     AAEQAAAQAKAQAEQEAAARAAQAQAQAQSVAAAQAAVTQAVPTPAPAQAQPVVAPAA
                     MVSTPAVSYAYDPSNPYPVGQCTWGVKALAPWVGNYWGNGGQWASSAAAAGFRVGATP
                     MVGSVVVWNDGGYGHVAYVTGVQGGQIQVMEANYAGNQSIGNYRGWFSPGAVSYIYPN
                     "
     gene            4170..5132
                     /locus_tag="TVB59_000879"
     CDS             4170..5132
                     /locus_tag="TVB59_000879"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEL1009787.1"
                     /translation="MSYSDLKLFALSSNKELAEKVAAAMGIQLGKSTVRQFSDGEIQV
                     NIEESIRGHHVFILQSTSSPVNDNLMEILIMVDALKRASAEKISVVMPYYGYARQDRK
                     ARSREPITSKLVANMLEVAGVDRLLTVDLHAAQIQGFFDIPVDHLMGAPLIADYFDRH
                     GLVGDDVVVVSPDHGGVTRARKLAQFLQTPIAIIDKRRSVDKMNTSEVMNIIGSVEGK
                     KCILIDDMIDTAGTICHAADALAEAGATAVYASCTHPVLSGPALDNIQKSAIEKLIVL
                     DTIYLPEERLIDKIEQISIADLIAEAIIRIHEKRPLSPLFELGK"
     gene            5492..6262
                     /gene="recO"
                     /locus_tag="TVB59_000880"
     CDS             5492..6262
                     /gene="recO"
                     /locus_tag="TVB59_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEL1009788.1"
                     /translation="MRIQRSLGIVLYNKNYREDDKLVKIFTEAAGKRMFFVKHIGRSK
                     LAPVVQPLTAADFLLKINDSSLSYIEDYNQVEAYRHINEDFFRLSYASYVLALADAAI
                     PDNEPDPQLFAFLKKTLDLMEEGLDYDILTNIFEVQILDRFGVRMNFHDCVFCHRTNL
                     PFDFSHKYSGVLCPQHYHEDERRYGLDPNVIYLLNRFQTLNIDELKTISVNTGMKKKL
                     RLFIDALYEDYVGIRLKSKVFIDDLAKWGDIMKNKQGL"
     gene            6378..7385
                     /gene="plsX"
                     /locus_tag="TVB59_000881"
     CDS             6378..7385
                     /gene="plsX"
                     /locus_tag="TVB59_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEL1009789.1"
                     /translation="MKKIAIDAMGGDYAPKAIVEGVNQAIESFSDIEIQLYGDQSRIE
                     SYLVKSDRVSIVHTDEKINSDDEPAKAIRRKKNASMVLAARAVKDGRADAVLSAGNTG
                     ALLAAGLFIIGRIKGVDRPGLLSTLPTVDGSGFDMLDLGANAENTAEHLHQYAILGSF
                     YAKHVRGIAKPRIGLLNNGTEATKGDSLRKEVYNFLASDSSLQFIGNVEARDLMSGVA
                     DVVVADGFTGNAVLKSIEGTAMSIMGQLKSAIAVGGVKAKFGALLLKSSLYDLKDTLD
                     YSSAGGAVLFGLKAPLVKSHGSSDAKAIFHTIKQVRTMLETDVVGQLVEEFSKESDVN
                     D"
     gene            7378..7626
                     /locus_tag="TVB59_000882"
     CDS             7378..7626
                     /locus_tag="TVB59_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514702.1"
                     /note="carries the fatty acid chain in fatty acid
                     biosynthesis; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEL1009790.1"
                     /translation="MTEEVILEKIIALIKKQRSRIDFDITEKTALKDDLGVDSIELVE
                     FVINIEDEFGIDIPDEDVDGMVSMGDMLNYLVKRLNQS"
     gene            7776..8486
                     /locus_tag="TVB59_000883"
     CDS             7776..8486
                     /locus_tag="TVB59_000883"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEL1009791.1"
                     /translation="MSNQLIYSGKAKDIYETADDGIVLISYKDQVTMLNGAHKEMIEG
                     KGSLNNQISALIFDRLNRVGVSTHFIKQLSETEQLNKRVAIIPLEVVLRNVAAGSFSK
                     RFGVKEGQALDEPIIELYYKNDALDDPFINDEHVSFLKLATDEQIAYIKQETHRINAY
                     LKEWFASVGLTLVDFKLEFGFDKEGMLILADEFSPDNCRLWDNAGRHMDKDVFRRQLG
                     SLTQAYETVLERLRALDQ"
     gene            8665..12405
                     /locus_tag="TVB59_000884"
     CDS             8665..12405
                     /locus_tag="TVB59_000884"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEL1009792.1"
                     /translation="MNKRIFVEKKADFQIKAQVLLKELKHQLQLKTLVDLRIVQVYDV
                     FHLDQELLLTAIKHVFSEQVTDQVLSEEALQADLKRYAFFAIEALPGQFDQRAASSQE
                     ALLLLGASTDVTVLTSQLYLVNQDIAAEELEALKQYLLNPVDSRFKDILAGLDDQDFS
                     VADKVIPTLDVFNDYTAENLARYRSEQGLAMEVEDLLFIQDYFKTKGRVPTETELRVL
                     DTYWSDHCRHTTFETELKTLDFSASHFEKQLQATYETYLAMRDELGRSERPQTLMDMA
                     TIFGRYERANGRLEDLEVSDEINAYSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRLSGAGDITSPLSETRKGKLPQQVISRQAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKENVVREKPRTGDVVVLLGGK
                     TGRDGIGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRRGDVTRLIKKSNDF
                     GAGGVCVAIGELAAGLNINLDKIPLKYAGLNGTEIAISESQERMAVVICPKDLEAFMS
                     ACHKENIHAAVVAAVTEKPNLVMTWNGQTIVDIERSFLETNGVRVSVAAKVVDSGAPI
                     PEARQTTAETLEADTIAVLSDLNHASQKGLQTLFDSSVGRSTVIHPLGGRYQMTPVEG
                     SVQKLPVQHGVTKTVSVIAQGYHPYIAEWSPYHGAAYAVIEATARLVATGSHWHKARF
                     SYQEYFQRMDKQAERFGQPVAALLGAIEAQVQLGLPSIGGKDSMSGSFEELTVPPTLV
                     AFGVTTAHVDHILSPEFKAAGENIYYIPGQAISEVIDFELIKSNFMTFEAIQKKHNIS
                     SASAVKYGGVVEALALAAFGNRLGACVTLPELDRSLTAQLGGFIFTSKEEITGVIKLG
                     QTTSDFTLVVNDVKLSGARLLKAFEGSLEQVYPTVFQQAGELKPVPVVTTALAAQFKE
                     KIAQPVVYIPVFPGTNSEYDSAKAFEREGARVNLVPFVTLNEAAIDASVDTMVDHIHQ
                     AHIIFLAGGFSAADEPDGSAKFIVNILLNEKVRMAIDAFIEKGGLIIGICNGFQALVK
                     SGLLPYGRFEAVHEASPTLFYNDANQHVAKMVETRIANTNSPWLAGVRVGDIHAVAVS
                     HGEGKLVVTERELAELCKNGQIFSQYVDLDGNPSMDSRYNPNGSVNAIEGLTSKNGQI
                     IGKMGHSERFEEGLFQNIPGNKDQWLFRSAVHYFRGDHVGID"
     gene            12524..13981
                     /locus_tag="TVB59_000885"
     CDS             12524..13981
                     /locus_tag="TVB59_000885"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003104332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEL1009793.1"
                     /translation="MTYDVKSLNEECGVFGIWGHPHAAQVTYFGLHSLQHRGQEGAGI
                     ISNDNGELHQHRDVGLLSEVFKDSSDLDKLKGHAAIGHVRYATAGTASINNIQPFLYR
                     FTDAQFGLCHNGNLTNAMSLKKALESEGAIFNASSDTEILMHLIRRSHHPEFLGKVKE
                     ALNTVKGGFAYLLMTENQLIAALDPNGFRPLSIGRMKNGAWVVSSETCAFEVVGAEWV
                     RDVMPGEVIIIDDQGITYDCYTTTTQLAICSMEYIYFARPDSTIAGVNVHTARKRMGK
                     RLAQEFQHEADIVVGVPNSSLSAAMGFAEASGLPNEMGLVKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVNLLREAGATEVHVAIGSPELKY
                     PCFYGIDIQTRRELISANHTAAEVCDIIGADSLTYLSLDGLIEAIGLDTKAPNGGLCV
                     AYFDGQYPTPLYDYEEAYLKSLEEKVSFHIDQVTK"
     gene            14038..15060
                     /locus_tag="TVB59_000886"
     CDS             14038..15060
                     /locus_tag="TVB59_000886"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEL1009794.1"
                     /translation="MSKNAYAQSGVDVEAGYELVERIKKHAERSKRLGVMGGLGGFGG
                     LFDLSKTGVKEPVLVSGTDGVGTKLMLAIQYDKHDTIGQDCVAMCVNDIIAAGAEPLY
                     FLDYLAAGKNEPAKLEQVIAGIAEGCVQAGAALIGGETAEMPGMYGQDDYDLAGFAVG
                     IAEKSQLIDGSRVAEGDHLLGLASSGVHSNGYSLVRRIFAGYTGEELLPELDGKKLKE
                     VLLEPTRIYVKAVLPLIKSGLVAGIAHITGGGFIENLPRMFSKELAAEIEEASLPVLP
                     IFKVLETYGKINHEEMFEIFNMGIGMVLAVKPEHVEQVKACLDEPVYDIGRVVTRTVA
                     SVVMKP"
     gene            15057..15614
                     /gene="purN"
                     /locus_tag="TVB59_000887"
     CDS             15057..15614
                     /gene="purN"
                     /locus_tag="TVB59_000887"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEL1009795.1"
                     /translation="MTRIAVFASGNGSNFQTIAEQFPVAFVFSDHCDAHVLSRACALG
                     VLSYSFELKDFENKQAYEQTLVALLQRHQIDLIVLAGYMKIVSTTLLDAYEGKIINIH
                     PAYLPEFPGAHGILDAWQAGVSQSGVTVHWVDSGIDTGKIIKQVRVPRLSDDTLESFE
                     ARIHEAEYQLYPEVLDSLGVERLNR"
     gene            15761..17308
                     /gene="purH"
                     /locus_tag="TVB59_000888"
     CDS             15761..17308
                     /gene="purH"
                     /locus_tag="TVB59_000888"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEL1009796.1"
                     /translation="MTKRALISVSDKRGIVDLARELKHLGWDIISTGGTRLALEEAGV
                     VTVAIDDVTGFPEMMDGRVKTLHPLIHGGLLARRDIEHHLQAAKQNRIELIDLVVVNL
                     YPFKETICRPDVTYDVAVDMVDIGGPSLLRSAAKNHASVTVVVDPTDYPLVLGELAST
                     GSTSYQTRQSLAAKAFRHTAAYDAVIADYFTRQAGETKPEKLTLTYDLKQSMRYGENP
                     QQAADFYQRALPTTYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKERPTVVALKHM
                     NPCGIGQADDIETAWDFAYAADPVSIFGGIVVLNREVDLATAEKLHAIFLELIIAPGY
                     SKEALAVLTHKKKHLRILELPFAAQEASEIEAEYTGVLGGLLVQNQDVVTESPADWIV
                     VTKRQPNEQEMAALAFAWKTIKYVKSNAIVIANDHMTLGVGPGQTNRIASIRIAIAQA
                     TGQLEGAVLASDAFFPFADSIEEIAAAGIKAIIQPGGSIRDSESIAAANQHGITMIFT
                     GVRHFRH"
     gene            complement(17686..18840)
                     /locus_tag="TVB59_000889"
     CDS             complement(17686..18840)
                     /locus_tag="TVB59_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HEL1009797.1"
                     /translation="MKKVYQLLASGAILLGGNGAISSATTTISQGQSGIVHAAVLGDN
                     YPSKWKQGFGADPWNMYLRQCTSFVAFRLHSSNGFSLPRGYGNVESWGRIAKHQGYHV
                     DHTPRVGAVAWWDKGFNQSHALYGHVAWVAEVNGDTVIIEEYNYNAGQGPEKYHKRQI
                     HKHQVSGYIHFKDLDHNSTSHTQMLHASQAGSTRLAKSGTYYFSSQSPIKAEATLASP
                     DLAYYHTGQLVHYDQTLVADGYEWLSYIGHSGNHRYIPIHKLPVQPQQHSQASIDKPK
                     PVATTPIKVGDTVAFPGVFRVDQVAQNMIASSELAGGEPTSLNWIDSAPLHETDHKGR
                     IAGNQILQVGDYFVVSGTYKVLKVDQPSKGIYVQMGSRGTWLTIDKAKKV"
     gene            19231..20493
                     /gene="purD"
                     /locus_tag="TVB59_000890"
     CDS             19231..20493
                     /gene="purD"
                     /locus_tag="TVB59_000890"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEL1009798.1"
                     /translation="MKLLVIGSGGREHAIAKKLLESKGVEQVFVAPGNDGMTLDGIER
                     VDIDISEHSALIAFAKTNHIAWTFVGPDDALAAGIVDEFNQSGLKAFGPSRLAAELEW
                     SKDFAKQIMVKYGIPTAAYGTFSDFAKAKAYIEEKGAPIVVKADGLALGKGVVVAETV
                     EQAVEAARDMLLDNKFGDSGARVVIEEFLAGEEFSLFAFVNGDQFYLMPTAQDHKRAL
                     DGDKGPNTGGMGAYAPVPHLSQSVVDTAVETIVKPVLKGMMTEGRPYLGILYCGLILT
                     EDGPKVIEFNARFGDPETQVILPRLTSDFAQNITDILEGNTANITWSDEGVTLGVVLA
                     SNGYPLAYKKGVLLPAKTTGDIITYYAGVKLAENGKALLSNGGRVYMLVTTAVTVPAA
                     QEKIYTELAQQNTEGLFYRNDIGRKAVK"
     gene            20722..21210
                     /gene="purE"
                     /locus_tag="TVB59_000891"
     CDS             20722..21210
                     /gene="purE"
                     /locus_tag="TVB59_000891"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEL1009799.1"
                     /translation="MKPIISIIMGSKSDWTTMQKTAEILDQFGLAYEKKVVSAHRTPD
                     LMFTYAEKARERGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGLDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALTALRILSIEDETIAEQLSHFHKEQGRIAEESTHE
                     LN"
     gene            21197..22270
                     /gene="purK"
                     /locus_tag="TVB59_000892"
     CDS             21197..22270
                     /gene="purK"
                     /locus_tag="TVB59_000892"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEL1009800.1"
                     /translation="MNSTKTIGIIGGGQLGQMMAISAIYMGHKVITLDPAADCPASRV
                     SEVIVAPYSDVEALRQLTERCDILTYEFENVDADALDTVVKEEQLPQGTELLRISQNR
                     IFEKDFLANKASAAVAPYKVVTSSLDLENLDFSKKYVLKTATGGYDGHGQVVIRSEAD
                     LEEANKLANTAECVLEEFVSFDREISVIVSGNGTDVTVFPVQENIHRNNILSKTIVPA
                     RISEAVSAKSQAMAVKIAEQLNLSGTLCVEMFVAGDEILVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGQPLPAVKLHAPAIMLNVLGQHMEQAQRYATENPSAHLHLYGKIE
                     AKHNRKMGHVTVFNSQSDEVEEF"
     gene            22285..22509
                     /locus_tag="TVB59_000893"
     CDS             22285..22509
                     /locus_tag="TVB59_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HEL1009801.1"
                     /translation="MIKIIVHAFIENGETGVVEVVFASENQESISEKMTELQKQYPND
                     YLAIYDLPLDTDLSQLAHYPSIAIGKGEFE"
     gene            23106..24398
                     /gene="purB"
                     /locus_tag="TVB59_000894"
     CDS             23106..24398
                     /gene="purB"
                     /locus_tag="TVB59_000894"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEL1009802.1"
                     /translation="MLNRYSRPEMAKIWSEENKYRAWLEVEILADEAWAELGEIPKED
                     VAKIRANASFDINRILEIEEETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIVAEKAKEHKMTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNQERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCGKLGIRPQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMVTAYENVALWHERDISHSSAERIITPDTTILINYMLNRFGNIVKNL
                     TVFPENMTRNMNSTFGLIYSQRVMLKLIEKGMTREEAYDLVQPKTAYSWDNQVDFKPI
                     LEADENITAKLRQDELDELFNPAYYTKRVDAIFDRLGL"
     gene            24696..25609
                     /locus_tag="TVB59_000895"
                     /pseudo
     CDS             24696..25609
                     /locus_tag="TVB59_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677204.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            25692..25790
                     /locus_tag="TVB59_000896"
     CDS             25692..25790
                     /locus_tag="TVB59_000896"
                     /inference="COORDINATES: protein motif:HMM:NF038244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system DWW-type pheromone"
                     /protein_id="HEL1009803.1"
                     /translation="MFKKYQYYLFLAALFLLHSAQLLSDIDWWRVG"
     gene            25824..26831
                     /gene="ruvB"
                     /locus_tag="TVB59_000897"
     CDS             25824..26831
                     /gene="ruvB"
                     /locus_tag="TVB59_000897"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEL1009804.1"
                     /translation="MTRILDNDLIGDEGSVERTLRPQYLREYIGQDRVKDQLMIFIEA
                     AKRREESLDHVLLFGSPGLGKTTMAFVIANELGVHLKQTSGPAIEKAGDLVAILNDLE
                     PGDVLFIDEIHRMPMAVEEILYSAMEDFYIDIMIGAGDTSRSVHLELPPFTLIGATTR
                     AGMLSNPLRARFGITGHMEYYQTADLTEIVERTADIFDMTIKHEAAYELARRSRGTPR
                     IANRLLKRVRDYAQIMGDGMITTQITDKALTMLDVDQEGLDYVDQKILRTMIEVYQGG
                     PVGLGTLSVNIAEERDTVEDMYEPYLIQKGFIMRTRTGRVVTEKAYQHLGYPYEKTIK
                     T"
     gene            27072..27530
                     /locus_tag="TVB59_000898"
     CDS             27072..27530
                     /locus_tag="TVB59_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEL1009805.1"
                     /translation="MKKVCFVCLGNICRSPMAEFVMKSMASPDELQVESRATSGWEHG
                     NPIHHGTQSLLQQYQISYDTKKTSQQITSFDFEAFDYIIGMDSHNIRDLKQMSKHQWD
                     SKIHLFIEGGVPDPWYTGDFEETYRLVKAGCQHWLSQISAEHESHVEIDE"
     gene            27536..27937
                     /locus_tag="TVB59_000899"
     CDS             27536..27937
                     /locus_tag="TVB59_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009806.1"
                     /translation="MKAIINNIQKWQITRTKLEIISVLVIIVCGLSVFTLTISSKASL
                     TYDNGQIKYTGYVLNHRMNGKGKLVYPNGDTYVGDFNKGVFDGEGTFTASTGWSYSGQ
                     FKKGQADGKGTLKAKDSKVYKGTFKQGIFQK"
     gene            27934..29715
                     /locus_tag="TVB59_000900"
     CDS             27934..29715
                     /locus_tag="TVB59_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEL1009807.1"
                     /translation="MRIKWFSFIRVTGLLLVLLYHFFKHTFSGGFVGVDIFFTFSGYL
                     ITALLIDEYVSKQTIDVVAFFRRRFYRIVPPLVLLILLTIPFTFLVKSDFIAGIGQQI
                     AAALGFTTNSYELLTGSSYESQFIPHLFVHTWSLAIEVHFYLLWGLLVWLLAKKGYSQ
                     KKFRGILFLISSAVFTLSYFSMFIRAFFVSDFSSVYFSTLSHSFPFFLGAMFATMTGI
                     KDTTVRFQKNVKLWPRLHVIGVMAGAFALLLFLTLVLDFNHIFTYLFGFVLASLFASV
                     MIYAARVLSDQTPTWQEPLLVTYLADISYGIYLFHWPFYIIFTQLMSNWLAVILTVFF
                     SVVFSTLSYYIIEPLIQGKTPQLFGLAIDCNPYKKWLSGLALGLFLLMVGTCLTAPRV
                     GNFETQLLVDSLQQSQSNLNKTHTLAAGDAHALSDVSIIGDSVALRSSDAFSKLMPTA
                     QLDAAVSRNFSEAFELFENHIQSKSLSKTTVLAVGVNSLYNYAQDIQGFIYALPKGHR
                     LVIVSPYDAKNAAQVAEAREHLLQLAKKYSYVTVADWYKAAVENPNIWYGSDGVHYNN
                     DAKLKGADLYVSTIQAAVERAAKKDAK"
     gene            30135..32777
                     /gene="adhE"
                     /locus_tag="TVB59_000901"
                     /gene_synonym="adhC"
     CDS             30135..32777
                     /gene="adhE"
                     /locus_tag="TVB59_000901"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEL1009808.1"
                     /translation="MTEKNSTVETTSVAATIDALVQKGLVALDKMRQLTQEQVDYIVA
                     KASVAALDAHGELAKHAYEETGRGVFEDKATKNLFACEHVVNNMRHQKTVGIIEEDDV
                     TGLTLIAEPVGVICGITPTTNPTSTAIFKSLISLKTRNPIIFAFHPSAQESSAHAARI
                     VRDAAIAAGAPEDCVQWIETPSLEATNALMNHDGIATILATGGNAMVKAAYSCGKPAL
                     GVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVSEFKS
                     YHTYFVNKKEKALLEEFCFGAKANSKNCAGAKLNPNIVGKPAAWIAEQAGFTVPEGTN
                     ILAAECKEVSENEPLTREKLSPVIAVLKAESRTDGVEKARQMVEFNGLGHSAAIHTAD
                     ADLAKEFGTKIRAIRVIWNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVSAVN
                     LLNIKKVGRRRNNMQWFKVPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGFLDR
                     IIEQLDLRRNKVVYQIFADVEPDPDITTVMKGTELMRTFKPDTIIALGGGSPMDAAKV
                     MWLFYEQPEVDFHDLVQKFMDIRKRAFKFPELGKKTKFVAIPTTSGTGSEVTPFAVIS
                     DKANNRKYPIADYSLTPTVAIVDPALVLTVPGFIAADTGMDVLTHATEAYVSQMANDF
                     TDGLALQAIKIVFENLEKSVKEADFESREKMHNASTMAGMAFANAFLGISHSMAHKIG
                     AQFHTVHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIAKLLGLPASTP
                     EEGVESYAKAVYDLGCRLGIKMNFRDQGIDEEEWKAHTRELAYLAYEDQCSPANPRLP
                     MVEHMEEIMNDAYYGYAERPGRRK"
     gene            33272..34324
                     /locus_tag="TVB59_000902"
     CDS             33272..34324
                     /locus_tag="TVB59_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEL1009809.1"
                     /translation="MKAATYVAPGQLELIDQPKPEILAPTDAVVRLLKTTICGTDLHI
                     LGGDVPETTHGTILGHEGIGIVESVGSAVNNFKVGDKVIISCITACNTCYYCKKGIPA
                     HCESGGWILGHLINGTQAEYVHIPQADGSLYHAPKTVEDDALVMLSDIFPTSYEIGVQ
                     SAKVKPGDTVCIVGAGPIGLAALLTAQFYSPAKLIMVDLSESRLEAAKRFGATDTICS
                     GDLDDIVKKVHELTDGRGVDVAIECVGYPATFDICQKIIAIGGHVSNVGVHGKPVSLD
                     LQDLWIKNITMSTGLVNANTTEMLLNVLKSGKIDATKMVTHHFKLSEVEKAYEVFKNA
                     GSNNALKVIIENDITA"
     gene            34527..35543
                     /gene="adhP"
                     /locus_tag="TVB59_000903"
     CDS             34527..35543
                     /gene="adhP"
                     /locus_tag="TVB59_000903"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEL1009810.1"
                     /translation="MKAVVVNQTSSGVEVVEHDVPSIGHGEALVKVEYCGVCHTDLHV
                     AHGDFGQVPGRILGHEGIGIVEKLGEGVTSLKVGDRVSIAWFFEGCGHCEYCTTGRET
                     LCRSVKNAGYSVDGGMSEYAVVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAGA
                     APGQWIVIFGAGGLGNLAVQYAKKVFNAHVVAVDINNDKLELAKEVGADIVVNGKEIE
                     DVAGYIQEKTGGAHGVVVTAVSKVAFNQAIDSVRAGGTVVAVGLPSEYMELSIVKTVL
                     DGIKVVGSLVGTRKDLEEAFAFGAEGLVVPVVEKVPVETAPEVFDEMERGLIQGRKVL
                     DFTL"
     gene            36259..>37386
                     /locus_tag="TVB59_000904"
     CDS             36259..>37386
                     /locus_tag="TVB59_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1009811.1"
                     /translation="MKEIVRSHRLLYVIVAFFSVISAFLMTLFSIQLGKILDSISNSS
                     SELLFQIVVCVCTIMAWFIMIWSYSYFKSYYVKKVILDLKERLFIGYLLREFNEIDTC
                     DRYNSDFLNNVTKNIDIIQENLLVPRVAVIVDLASMVTSVVAIVLIEWRLALVFLLLS
                     IVTVFLSQIPGKLMSKATRYYSEKSNHYLAEMTSFIEGFEQIKLLNIQKWIQKIEQNT
                     TLEFEDSRQKYQYRKDLASNTGMFLSFFSQVACMVAGIFFVRNNLLTVGLLVASIQLL
                     NGVFGPLQSFLYNKNLIKSTGTILTSIQEVLDKTNFVNGYIENKTFYEGDISSISINN
                     LTYQVENRKIFTNFSFEFKKGNTYAIIGPSGVGKTTLAKLIL"
BASE COUNT        10680 a         6667 c         8783 g        11256 t
ORIGIN      
        1 tcccataagt tatgaatagg tcccgtagtg tagcggttat cacgtcgccc tgtcacggcg
       61 aagatcgcgg gttcgattcc cgtcgggacc gtaggactcg ttagctcagt tggtagagca
      121 tttgactttt aatcaaaggg tcactggttc gagcccagta cgggtcataa aggcgggttt
      181 ggcggaattg gcagacgcac cagatttagg atctggcgct taacggcgtg ggggttcaag
      241 tcccttaacc cgcatagata ggccggctta gctcagttgg tagagcatct gatttgtaat
      301 cagagggtcg cgtgttcaag tcatgtagcc ggcattgata gagttgcgaa cgtagttcag
      361 tggtagaaca ccaccttgcc aaggtggggg tcgcgggttc gaatcccgtc gttcgctttt
      421 ggggagccgg ggtggcggaa ctggcagacg cacaggactt aaaatcctgc gatggttaac
      481 atcgtaccgg ttcgattccg gtcctcggca tagcataagg aaaagcaccc ttagctcaac
      541 tggatagagt acctgactac gaatcaggcg gttagaggtt cgactcctct agggtgcata
      601 gttacgggaa gtagctcagc ttggtagagt acttggtttg ggaccaaggt gtcgcaggtt
      661 cgaatcctgt cttcccgatt agtttgatgg cggtgtagct cagctggcta gagcgtccgg
      721 ttcatacccg ggaggtcggg ggttcgatcc ccttcgccgc tattttgttt ttggattgtt
      781 ttggaccttt agctcaactg gttagagcac tcggctcata accgagcggt cgtaggttcg
      841 agtcctacaa ggtccataat ggtggaggat tacccaagtc cggctgaagg gaacggtctt
      901 gaaaaccgtc aggcgtgtaa cagcgtgcgt gggttcgaat cccacatcct cctttaaaga
      961 ttatcgcggg atggagcagt taggtagctc gtcgggctca taacccgaag gtcgtaggtt
     1021 caaatcctgc tcccgcaatt atataaaaga tatatgctgg ttggctcggt agctcagttg
     1081 gtagagcaat ggattgaagc tccatgtgtc ggcggttcga ttccgtctcg cgccatttta
     1141 gcgggtgtag tttagtggta aaactacagc cttccaagct gttgtcgcga gttcgattct
     1201 cgtcacccgc tttatagttt tcccaagcta tagtgtgctt gggcgcgtag ctcaggtggt
     1261 tagagcgcac gcctgataag cgtgaggtcg gtggttcgag tccactcgtg cccatcatta
     1321 tttggagaat tactcaagag gctgaagagg acggtttgct aaatcgttag gtcgggtaac
     1381 tggcgcaagg gttcgaatcc cttattctcc gtattgtaaa ggtgattatc atactgataa
     1441 tcgttttttt atttttagag gtgattttat tgaaaaagct taacctatct cgtctctttt
     1501 tttggttaac atcattagct ttactggctt tgaccttggt tcttcttttt agagtagcta
     1561 tttctccata tttatcaatg attatccgaa atcccgttac aaaaattgat gctataatgt
     1621 ctaagccttt tgctgttata aaggagggtg caaaggaatt agatagcttg atgtctgctt
     1681 tttctgaaaa taagcattta aaaaaggaac ttaggtccta taaattggat cagttacagg
     1741 ttgacaagct aaaatctgaa aatcgagagc tcaaggaact gttagggttg gattatggta
     1801 ctgataatca atttgctgcc agaatgatat caagaaatcc ttatagctgg aataaatcgc
     1861 tggtcattga tagcggcaaa agggaaatta aggagaagtc tttggttact tcagagcttg
     1921 gacttattgg tcgtgttaca gctgttagcc agtcatctgc tcatgttgaa ttgttaacat
     1981 ctgggaagaa tattgagttg ccgattaaaa ttgtagataa ggataaggtg atttatggca
     2041 atttaaaggc atttaaatca gaaagtaaaa caatggttgc cagcgaattt aattctaatg
     2101 actcaatatc attagatgct aaggtttata caagtggatt agatggtgag actgtggcag
     2161 atattcctgt tggaaaggtt acgggcttta aaaatgctgc tgataagcta aagcgtcgta
     2221 tttttataaa attgtatgct gatactgata atcttgacta tgttcttgtt gttggaaaag
     2281 agtgaatatg aaaaaatctt cagagctatt agtccttttg ccttttcttt tattttttgt
     2341 tgatgcacac gtgtcagacc tgatcagctc aatgttacct gagggttact cggtagtatc
     2401 acacctcttt ttactgtttt tcctgatcct tatggtagcg tttagatcta agggagttat
     2461 ttgtttcttc tctcttcttt taggattatt gtttgattat tattattttg atcatatagg
     2521 gattttgtct cttgccttgc cttttggaac aatgatcgtt ctagggctat taaggttctt
     2581 ttctggttcc attagtcagc tacaattttt ccttttcttt actctttata tgtttcttgt
     2641 agatgtatca agctttattt tggcaaacag ctatcagtta actgatatga cttttcctta
     2701 tgtaatgacg tttcagcttg ctccgacttt aatcgtcaat ctccttattt tgttttgctt
     2761 tagaaaatta atattaagtc aattttattg attattacat acaactgtaa cagatgcgta
     2821 acattaaacg cttgattttt tgatagaata taatgtgtct tatcgaaaag gagtaatttt
     2881 tttagtatga aaaaaagaat tctatcagcg gttcttgtaa gcggtgtgac ccttggaaca
     2941 gcaactacag tgggagcgga tgatttagat tccaaaatag cgttgcaaaa ttcagttatt
     3001 tctaatttaa ataaagaaca aaaagctgcg caggatagaa tgaagacttt gcaaagtcag
     3061 gttagctcat tacaatctga acaagaaagg ttagtcgcta aaaatggtga gcttgaagcg
     3121 cgatctgctc agtttgagca ggagattcaa gtgcttgcca gtcaaattat tgctcgtaat
     3181 gaaaagttaa aaggacaggc tcgtagtgct caaaagggaa atacgttagg ttacctcaat
     3241 gcacttttga attctaagtc aatttctgac gttattactc gtttggttgc tattaataga
     3301 gctgtgtcag ccaatgcaca gatgttggaa aagcaaaagg ctgataagct ttctcttgaa
     3361 gaaaagcaac aggaaaatca agaagcgatt aatacaattg cttcaaatat tacagcaatt
     3421 gaatcaaacc aagtagcttt aaagactcaa caagcagatt tagaggttgc caaggtagat
     3481 ttggcgcttc aattagcaac tgctgaggac gagaaggcta gcttgattac ccgtaaagag
     3541 gctgcagagc aggcagcagc tcaagccaag gctcaggcag agcaggaagc agcagccaga
     3601 gcagcacagg ctcaagctca agcacagtct gtagcggcag ctcaagcagc agtgactcaa
     3661 gccgtaccaa caccagctcc agcgcaggca cagcctgttg tggcgccagc agctatggtt
     3721 tcaacaccag cggtgtcgta tgcctatgat ccttctaatc cgtaccctgt cggccaatgt
     3781 acttggggag ttaaggcttt agctccttgg gttggcaatt attggggaaa tggtggtcaa
     3841 tgggcatcaa gtgcagcggc agcaggtttc cgtgtaggtg caacaccaat ggttggctct
     3901 gttgttgtat ggaatgatgg tggctatggt cacgttgcct acgtaacagg tgttcagggt
     3961 ggacagattc aagttatgga agccaactat gctggaaatc aatctattgg caattatcgt
     4021 ggttggttta gcccaggtgc tgtatcgtat atttatccaa attagaaaat aagtaaaggt
     4081 aagaatcagg attcttacct ttttatttcc attgaaaaat tgattgaaaa gggttaaaat
     4141 ggtataggat caaaactttg gaggaaaaaa tgtcttattc tgatttaaag ctgtttgcat
     4201 tatcgtcaaa caaggaatta gcagaaaaag ttgctgctgc gatgggaatt caacttggga
     4261 agtctacggt tcgccagttt tcagatggtg agattcaggt caatattgag gaatcaatac
     4321 gtggacacca tgtttttatt ttgcagtcaa caagctcgcc tgttaatgat aacctaatgg
     4381 aaattttaat tatggttgat gctttaaagc gtgccagtgc tgagaaaatt tctgtggtaa
     4441 tgccttatta tggctatgct cgtcaggatc gtaaggctcg ttcgcgtgag cctattacct
     4501 ctaaattagt cgctaatatg ctagaggtgg caggtgttga tcgtttattg actgttgatt
     4561 tacatgctgc gcagattcaa ggcttctttg atattcctgt tgatcatctc atgggagcac
     4621 ctttaattgc tgattatttt gatcgtcatg gtctagtagg tgatgacgtt gttgttgtta
     4681 gcccagatca tggtggtgtg acgcgtgctc gtaagctggc acaattcctc caaacgccaa
     4741 ttgctattat tgataagcgt cgtagtgttg ataaaatgaa taccagtgag gtgatgaata
     4801 tcattggtag tgttgaaggt aaaaaatgta ttctgattga tgatatgatt gatactgctg
     4861 gtaccatctg tcatgccgct gatgcgcttg ctgaagcagg agcaacagca gtttacgcat
     4921 catgtactca cccagtgctg tcaggaccag ctcttgataa tattcaaaaa tcagcgattg
     4981 aaaaattgat tgttttggat acgatctatt taccagaaga aagactgatt gataagattg
     5041 aacaaatctc tattgcagat ttgattgcgg aagctatcat tcgtatccat gaaaaacgtc
     5101 cattgtcacc cctatttgaa ttagggaaat gataaggtta gcctgaggta gtaagcctta
     5161 ggctttttta tgttttaaaa ggctatttga ttaccaaagc agtgtttgat ttaacgccat
     5221 agataggctt cactgtctta tggtaggtgt tgagctatta tagcaaaaag tcatgtgtag
     5281 gtgctgtgtt taaacagcta gcctatgatt catatagtta tggctagtga ctgttgagct
     5341 tcttattctc agagttgtta cgagccttaa gtacagtgtt agtcatgcaa ttttcctgga
     5401 ttttgggtat aatatagctg tatttaaggt gttttaaagg tctagtaaga aaggcattat
     5461 tactagctga gaagcttggt tatggagata tatgcgtatt cagaggtcac ttggtattgt
     5521 cttgtacaat aaaaactatc gtgaagatga taagctcgta aaaatattta cagaagcggc
     5581 gggcaagcgt atgtttttcg tgaaacatat tggtcgttct aaactagctc ctgtggtcca
     5641 gcctttaacg gctgctgatt ttctattgaa aatcaatgat tcgagccttt cttatataga
     5701 ggattataat caggtggagg cttatcggca catcaatgaa gattttttta ggctatccta
     5761 tgctagttat gtcttggctc tggctgatgc ggctattcca gataatgagc ctgatcctca
     5821 gttgtttgct tttttgaaaa agactcttga tctgatggaa gaagggctag attatgacat
     5881 tttaacgaat atctttgaag tccagatttt ggatcgtttt ggggtgagaa tgaattttca
     5941 tgattgtgtt ttttgtcaca gaaccaatct gccttttgat ttttctcata agtattcagg
     6001 tgtcctttgt ccgcagcatt accatgagga tgagaggcga tatggcttgg atcccaatgt
     6061 gatttatttg cttaatcgtt ttcaaacgct taatattgat gagctaaaga ctatttctgt
     6121 gaatactggt atgaaaaaaa agcttcgtct ttttattgat gccttgtatg aggattatgt
     6181 cggtattcgt ctaaaaagta aggtttttat tgatgatttg gctaagtggg gagatattat
     6241 gaaaaacaag cagggcttgt gagctattca ggtgtggatt tgtcctttta tgggaattgt
     6301 ctggggaata tgctataata gttacgttat tctctaggat atttttcgtt aagaaaaata
     6361 ggattaaagg agcaaaaatg aagaaaattg caatagacgc tatgggtggt gattatgccc
     6421 ctaaagctat tgttgagggt gttaatcagg cgatagaatc cttttcagat attgaaattc
     6481 agctttatgg cgatcaatca aggattgagt cttacctagt taaatcagat cgtgtgtcca
     6541 ttgttcatac agatgaaaaa attaattctg atgatgagcc agcaaaggct attcgtcgta
     6601 agaagaatgc ttctatggtt ttagctgcaa gggcagttaa ggatggtcgg gctgatgcag
     6661 ttctttcggc aggtaataca ggcgccttgt tagctgctgg tttgtttatt attggtcgta
     6721 tcaagggagt ggatcgtcct ggtttgctgt caactctgcc aacggttgat ggttcaggct
     6781 ttgacatgtt agatttgggt gccaatgctg aaaacacagc agagcattta caccaatatg
     6841 ctattttagg ctctttttat gcaaaacatg tgcgtggtat tgccaagcct cggattggct
     6901 tgcttaataa tggtactgag gcaactaagg gtgattctct tcgcaaggag gtctataatt
     6961 ttttagcttc agacagcagc ctacagttta ttgggaatgt tgaggcaaga gatttgatgt
     7021 ctggcgtggc agatgttgtg gtagcagatg gctttacagg aaatgctgtt ttgaagtcga
     7081 ttgaaggcac tgctatgagt attatgggac aattgaaatc agctatagca gtaggtggtg
     7141 ttaaggcaaa gtttggagct cttttattga agagtagcct ttatgactta aaggatactt
     7201 tagattattc cagtgcgggt ggggctgtat tgtttggtct taaagcacct cttgtgaaat
     7261 cacatggttc tagtgatgcc aaggctattt ttcataccat taagcaggtt cgtacgatgc
     7321 tagaaacaga tgtagttggc caattagttg aggagttttc taaggagagt gatgtaaatg
     7381 actgaggaag ttattttaga gaaaatcatc gcattaatca agaagcaaag aagtcgtata
     7441 gactttgaca ttacagaaaa aacagcacta aaggatgatt taggagtaga ttcgattgaa
     7501 ctggtagagt ttgttattaa tatcgaagat gaatttggta ttgatattcc tgatgaagat
     7561 gttgatggca tggtatctat gggagatatg ctaaattatt tggtcaagcg tttaaaccaa
     7621 agctaaatag ttttaaaaga gcaccagctc tttttttgtt tccgaaaaaa cgaacattat
     7681 aagtttattt tatattaaat gtaaataaat gttgaatatt tagtatgttt gtggtattgt
     7741 ttagatatta aatgcaaaga aaggcgaaca aataagtgtc taatcaactc atttattcag
     7801 gtaaggcaaa ggatatctat gaaacagccg atgacgggat tgtcttaatc tcctacaagg
     7861 atcaggtcac tatgctaaat ggagcacata aggaaatgat tgaaggaaaa gggagcctta
     7921 ataatcagat ttctgcctta atctttgata ggctaaatag ggttggcgta tcaactcatt
     7981 ttattaagca attatccgag acagaacagt taaataaaag ggttgcgatt attcctttgg
     8041 aggttgtttt acgaaacgtg gccgctggct cattttcaaa gcgctttggt gttaaagaag
     8101 gtcaggcttt ggacgagcca attattgagc tttattacaa gaatgacgct ttagatgatc
     8161 ctttcattaa tgatgagcat gtcagctttt taaagcttgc gactgatgag cagatagcct
     8221 acatcaaaca agagacgcat cgtattaatg cttatttgaa ggagtggttt gctagtgttg
     8281 ggttgacact ggttgatttt aagctagaat ttggctttga taaggagggg atgcttatcc
     8341 ttgctgatga gttttctccg gataattgcc gcttgtggga taatgcgggc cgtcacatgg
     8401 ataaggacgt ttttcgtcgt cagcttggca gtttgacgca agcctatgag actgttttag
     8461 aaaggctaag agcattggat caataaagac cagcttattt gttgtcagtt aagaaaggga
     8521 gctctttttt gtccgtcatg taagaaaata aatcagttca gactatttga gctgctgtct
     8581 aagaaaggct gtctgctatt ggagaaaaga gtcaggctag ttcttatttt gggctggttt
     8641 ctgattggac ttggtatatt aactatgaat aaacgtattt ttgttgaaaa gaaggctgat
     8701 tttcagatta aggcacaggt cctgttaaag gaattgaaac atcagctgca gttaaagaca
     8761 ctggttgatt tgcgtattgt gcaggtttat gatgtgtttc atttggatca ggagctgctt
     8821 ttaacagcta taaagcatgt tttctctgag caggtcactg atcaggtatt gtcagaagaa
     8881 gctttacaag cagatttaaa aaggtatgcc ttttttgcga ttgaagctct gcctggacag
     8941 tttgatcagc gtgcggcaag ctctcaggaa gccttattgt tgttaggagc ctcaactgat
     9001 gtgactgttt tgacctcaca gctttatttg gtcaatcaag acattgctgc tgaagaatta
     9061 gaagccttaa agcagtactt gttaaatcca gtggattcta ggtttaagga catattagcc
     9121 ggtcttgatg atcaggattt ttcagtagca gataaagtga ttccaacgct tgatgttttt
     9181 aatgattata cagcggaaaa tcttgctcgt tacaggtctg agcagggcct agcaatggaa
     9241 gtggaggatc tgctgtttat tcaggattat ttcaagacaa aggggcgagt gccaacagag
     9301 actgaactaa gggttttgga tacgtattgg tctgatcatt gtcgtcacac aacctttgaa
     9361 acagagctaa aaacgcttga tttttcagct tctcattttg aaaagcagct ccaagctacc
     9421 tatgagacct accttgctat gcgtgatgag ctaggtcgat ctgaaaggcc tcaaacgctt
     9481 atggatatgg ctaccatttt tggacgttat gaaagagcta atggtcgttt agaggatttg
     9541 gaggtttcag atgaaatcaa tgcttactca gtggaaattg aggtagatgt tgatggtgtc
     9601 aaggagcctt ggctgctcat gtttaaaaat gaaacacata atcacccaac ggaaattgaa
     9661 ccctttgggg gtgctgcaac ctgtattggt ggagctattc gtgatcctct gtcaggccgt
     9721 tcctatgttt atcaagccat gcggctttct ggtgcagggg acattacaag cccgctgtca
     9781 gagactcgta agggcaaatt accacagcag gttatttcga ggcaagcagc acatggttac
     9841 tcgtcatatg gcaatcaaat tgggctagcg actacttatg ttcgtgagta ttttcaccca
     9901 ggctttgttg ccaaacgtat ggagcttggt gcggtagttg gtgctgcacc caaggaaaat
     9961 gtggttcgtg aaaagccaag gacaggtgac gtggtggttt tgcttggtgg gaaaacagga
    10021 cgtgatggta ttggtggtgc gacaggatca tctaaggttc agacagttga gtctgtagaa
    10081 acagctggtg cagaggtcca aaaaggaaat gccattgagg agcgtaaaat ccaacgtctt
    10141 tttcgtcgtg gcgatgtgac acgcctcatc aagaagtcaa atgattttgg tgctggtggt
    10201 gtttgtgtag ccattggcga gcttgctgct ggtcttaaca ttaacttaga taagattcct
    10261 ttaaaatatg ctgggctaaa tggaacagaa attgccattt cagaatccca agagcgtatg
    10321 gctgtcgtga tttgtccaaa ggatttagag gcctttatga gcgcctgcca taaggaaaat
    10381 atccatgctg ctgttgtggc agctgtgaca gaaaaaccga atcttgttat gacctggaat
    10441 gggcagacga ttgttgatat tgaacgctca tttttagaga caaatggtgt gcgcgtgtct
    10501 gttgctgcta aggttgttga cagtggtgcg ccaataccag aagctcgtca aactactgct
    10561 gagacacttg aagcagatac cattgctgtc ttatcagacc tgaaccatgc tagtcaaaag
    10621 ggtttgcaaa ccctgtttga tagctcagtg ggtcgctcta cagtaataca tccgcttggt
    10681 gggcgctatc aaatgacacc tgttgaaggc tctgttcaga aattaccagt tcaacatgga
    10741 gtgacaaaga cagtctctgt tatcgctcaa ggctatcacc cttatatagc cgaatggtca
    10801 ccttatcatg gtgctgctta tgctgtaatt gaggcaactg ctcgtctggt cgcaacgggt
    10861 agccattggc ataaggcacg cttttcatat caggaatatt tccaaagaat ggataagcag
    10921 gcagagcgct ttggtcaacc ggtggcagcc ttgcttggag caattgaagc acaggtgcag
    10981 cttggcttgc cttctattgg aggtaaggat tcaatgtctg gtagctttga ggaattgaca
    11041 gtgccgccga ccttggttgc ctttggtgtg acgactgctc atgtagatca tatcctttca
    11101 ccagaattta aagctgctgg cgagaatatt tactatattc caggacaggc tatttcggaa
    11161 gtgattgatt ttgagttgat aaaatctaat tttatgactt ttgaggctat tcagaaaaag
    11221 cataatatta gctcagcttc ggctgttaaa tatggtggtg ttgttgaagc actggctctt
    11281 gctgcctttg gtaatcggtt aggggcttgt gtgacattac cagagcttga caggagctta
    11341 acagctcagc ttggtggctt tatctttaca tcaaaagagg aaatcacagg tgttatcaag
    11401 cttggtcaaa ctaccagtga ctttacattg gttgtcaatg atgtcaagct atctggagct
    11461 cgtctcttaa aggcttttga agggagcctg gagcaggttt acccgacggt atttcagcag
    11521 gcaggtgaat tgaagcctgt tcctgtagtg acaacagcac ttgctgctca gtttaaggaa
    11581 aaaatagctc agccagttgt ctatattcca gtttttccag gaactaactc agaatatgat
    11641 tcggctaagg cctttgaaag agagggtgca agggtgaact tggtgccttt tgttaccttg
    11701 aatgaggcag ctattgacgc ttcagttgac acgatggttg accatattca tcaagctcat
    11761 attatcttcc ttgcaggtgg tttttcagcg gcagatgagc cagatggttc agctaaattt
    11821 attgttaata tcctgctgaa tgagaaggtt cgaatggcga ttgatgcctt tattgaaaag
    11881 ggtggtctga ttatcggtat ttgtaatggc tttcaagctc tggtcaaatc agggctgctg
    11941 ccatatggac gttttgaggc ggtacatgag gctagtccaa ctctgtttta taatgatgcc
    12001 aatcagcatg tggctaaaat ggtagaaacg cgtattgcca ataccaattc tccttggctg
    12061 gcaggtgtca gggtggggga tattcatgct gttgcagtgt cacatggaga gggcaagctt
    12121 gtggtaacag aaagagaatt agcagagctt tgtaaaaatg gtcagatttt tagccagtat
    12181 gttgaccttg atggtaatcc aagcatggat agcaggtata atccaaatgg ctctgtcaac
    12241 gctattgaag gtcttaccag caaaaatggt cagattatcg gtaagatggg acattcagag
    12301 cgctttgaag agggactttt ccaaaatatt ccgggtaata aggatcaatg gttattccga
    12361 agtgcggtgc attattttag aggagaccat gtgggtattg actgaactgg gatatagcct
    12421 tgtaatagct aagatagctg ctattattgc tcagcctagc tgttagttct agcttagtta
    12481 atgacacaat cataattaaa agggcattag cccagaggta aagatgacat atgacgtaaa
    12541 atctcttaat gaggaatgtg gtgtttttgg gatttgggga cacccacatg ccgctcaagt
    12601 gacttatttt gggcttcata gcctacagca ccgcggccaa gagggagcag gtattatttc
    12661 aaatgataat ggggagcttc atcagcatcg tgatgtaggt ctcttgtcag aggtgtttaa
    12721 ggattcatct gatctggaca agctaaaggg acatgctgcc attggtcatg tgcggtatgc
    12781 gactgctggg acggcttcca ttaataatat tcagcccttt ttatatcgtt ttacagacgc
    12841 tcaatttggc ttgtgccaca atggtaattt gaccaatgct atgtcattga aaaaagcgtt
    12901 agagagtgag ggagctattt ttaatgcctc ttctgataca gaaattctaa tgcatttgat
    12961 tcgtcgtagt catcacccag aatttttagg aaaggtaaaa gaggcactca acactgttaa
    13021 agggggcttt gcttacctgc tgatgacaga gaaccagctg atagcagcgc ttgatccaaa
    13081 cggctttagg ccgttgtcta taggccgtat gaaaaatggg gcttgggtcg tctcaagtga
    13141 gacctgtgcc tttgaagtgg ttggtgctga gtgggttcgc gatgtgatgc caggtgaggt
    13201 cattatcatt gatgatcagg ggatcactta tgactgctat acgactacta cgcagctggc
    13261 tatctgctct atggaatata tttactttgc gcgtcctgat tcaaccattg ctggagtcaa
    13321 tgttcacacc gctcgcaagc gaatgggaaa gagactggct caggaatttc agcatgaggc
    13381 tgatattgtg gttggtgtgc caaattcctc attatcagca gcgatgggct ttgcagaagc
    13441 atcaggcctg ccaaatgaaa tgggattggt caagaatcaa tatacccaac gaacctttat
    13501 ccaaccaact caggagcttc gtgagcaggg agttcgaatg aaactttcag ctgtttcagg
    13561 tgttgtcaag ggcaaaaggg ttgtgatggt agatgattct attgtcagag ggacaacctc
    13621 acgacgcatt gttaatttgc tgcgtgaagc aggagctaca gaggttcatg tagcaattgg
    13681 tagccctgag ctcaaatacc cttgctttta tgggattgat attcagacaa gacgggagct
    13741 gatttcagct aatcatactg ctgctgaggt ctgtgatatt atcggtgctg atagcctgac
    13801 ttatttgtca cttgatgggc ttatcgaggc tattggactt gatacaaaag caccaaatgg
    13861 tgggctttgt gtggcttatt ttgacggtca gtatccaacg ccgctttatg attatgagga
    13921 ggcttatctc aagagcttag aagaaaaggt aagctttcac attgatcagg tgacgaagta
    13981 gcgctttatg gctaacatag aataaatgat ctaggcagct aaaataagga ggagaaaatg
    14041 tctaaaaatg cttatgctca atcaggtgtc gatgttgaag caggctatga gcttgttgag
    14101 cgaataaaaa agcatgccga gcgtagcaaa cgattgggtg ttatgggtgg tctaggaggc
    14161 tttggtggtc tgtttgacct gtcaaagact ggtgttaagg agcctgtttt ggtttcaggg
    14221 acagatggcg tcggaacaaa gctaatgctt gcaatccagt acgataagca tgacacgatt
    14281 gggcaggatt gtgtggcaat gtgtgtcaat gatattattg cagcaggtgc cgaacccctg
    14341 tattttcttg attaccttgc agcaggaaaa aatgagcctg ccaaattaga gcaggtgatt
    14401 gcaggtattg ctgagggctg tgttcaagca ggtgctgctc ttatcggtgg agaaactgct
    14461 gagatgcctg gtatgtatgg tcaagatgac tatgatcttg ccggttttgc ggttggtatt
    14521 gctgagaaat ctcagctgat tgatggttca agagtagctg agggagatca tctcctaggt
    14581 ttggcatcaa gtggagttca ttcaaatggt tattccttgg ttcgtcgtat ttttgccggt
    14641 tatactggtg aggagctgct tccagagctt gatggaaaaa agcttaagga ggtacttctt
    14701 gagccaactc gtatttatgt caaggctgtg ttaccactca ttaaaagcgg cttagtggca
    14761 ggaatcgctc atattacggg tggcggcttt attgaaaacc tacctcgtat gttttccaaa
    14821 gaactagccg ctgaaattga agaagccagc ttacctgtgc tgcccatttt taaagtcctt
    14881 gagacatatg gtaagatcaa tcatgaagaa atgtttgaga tttttaatat gggtattggc
    14941 atggtgcttg ctgtcaagcc tgagcacgtt gagcaggtga aggcctgtct tgatgagcct
    15001 gtgtatgaca ttggtcgcgt tgtgaccaga acagttgcta gtgtggtgat gaagccatga
    15061 caagaattgc cgtttttgct tctggtaatg gctccaattt tcaaacgatt gcagaacagt
    15121 ttccggttgc ctttgttttt tctgatcatt gcgatgctca tgttttaagt agagcctgtg
    15181 ctttgggtgt tctgtcctac agctttgaac taaaggactt tgagaataag caagcctatg
    15241 agcagactct tgtggcattg ctgcagcggc atcagattga tctcatcgtc cttgccggct
    15301 atatgaaaat tgtgagtaca accttacttg atgcttacga aggaaaaatc atcaacattc
    15361 acccagctta tttgccagaa tttccaggag cacatggtat tttagatgct tggcaagcag
    15421 gtgttagtca gtcaggagtg actgttcatt gggttgatag tggtattgat acaggaaaaa
    15481 tcatcaaaca ggtacgagta ccacgtttga gtgatgatac tcttgaaagc tttgaagcca
    15541 gaattcatga agcagaatac caattgtatc cagaggtact ggatagtctt ggagtagagc
    15601 ggcttaaccg ctgattgtgt aagattaata actattttcc ctattgtggc atttcgttta
    15661 tcatagcagc tgcgctaatg gtggctaaca aaggctagaa gacttgtttg atgatggcac
    15721 tgctattgag gaaaatagac ttttctaagg agaacttaaa atgactaaac gcgccttaat
    15781 tagcgtatca gataaaagag ggattgtgga ccttgctagg gagcttaagc atcttggctg
    15841 ggatattata tcaacaggag gaacaaggct tgctcttgaa gaggctggtg tagttactgt
    15901 tgctattgac gatgtgacag gctttcctga aatgatggac ggacgggtaa aaacgctgca
    15961 ccctctcatt catggtggct tacttgctcg tcgtgacatt gagcaccact tacaggcagc
    16021 aaagcaaaac aggattgaat taatagacct tgttgttgtt aacctttatc ccttcaaaga
    16081 aaccatttgc cgtccagatg tcacttatga tgtcgctgtt gatatggttg atattggtgg
    16141 tccttcactg ctgcgttcag cggctaaaaa tcatgctagt gttacggtag tggttgatcc
    16201 gacagattat ccgctcgttt taggagagtt ggctagcact ggcagtacaa gttaccaaac
    16261 ccgtcaaagc ttagcagcta aagcttttcg ccatactgca gcctatgatg cagtgattgc
    16321 agattatttt acaagacaag caggtgagac aaagcctgaa aagctcacgc ttacctatga
    16381 tttgaagcaa agcatgcgtt acggtgaaaa tcctcaacag gctgcagatt tttaccaaag
    16441 agcgctccca acaacctatt caattgcttc agccaagcag ctaaatggaa aagagctatc
    16501 attcaacaat attcgtgatg cagatgctgc gattcgtatt attcgtgatt ttaaggagcg
    16561 tccaaccgtt gtagcactca agcatatgaa tccatgtggt attggtcagg cagatgatat
    16621 tgagacagct tgggattttg cttatgcagc tgatccggtg tctatctttg gtggtattgt
    16681 tgtcctaaat cgtgaggtgg atctagcgac agcggagaag cttcatgcta tttttcttga
    16741 attgatcatt gcaccaggct attccaaaga agcgctagct gttctcaccc ataaaaagaa
    16801 gcacttgcga attcttgaat tgccatttgc tgctcaggag gctagtgaaa tagaagcaga
    16861 atatacagga gttcttggtg gtctactagt gcaaaatcaa gatgttgtca cagagtctcc
    16921 agcggattgg atagtggtga caaagcgtca gccaaatgaa caggaaatgg ctgctctagc
    16981 atttgcttgg aaaaccatca aatatgtcaa gtctaatgcg attgtcattg ctaatgatca
    17041 tatgactttg ggcgttggtc cagggcaaac aaaccgaata gcctctattc gtattgctat
    17101 tgcgcaagca acggggcagc ttgagggagc agttcttgct agcgatgcct tcttcccatt
    17161 tgcagacagc attgaagaaa ttgctgccgc tggtatcaag gctattatcc agcctggagg
    17221 ctctattcgt gattcagaat ctattgcagc tgccaatcag catggtataa ccatgatttt
    17281 cacaggtgtg aggcatttta gacattaata aagtaaaaag agactggagc caaaagagtt
    17341 gcactttaga aattcttggt taatatactt tattacctag ttggattcat taaaaagcga
    17401 acaagtctag ttttcataat ctcagaaaac tagacttgtt tgcttgtttt atttggtggt
    17461 catactattg tttcagcctc tttttactat gactaataca agaatttatg aaggaacaag
    17521 gctttatttt ttgttgtggt aacagtgacc agatccgtta tcaatcagta tttgagtatt
    17581 ttgagctcta gatgcatcac ttagatagga tattgcaaag gatacagctg ctgcatgtat
    17641 taggaaagca ttatcataaa aggctttttc gttagcctaa aggttttaga ccttctttgc
    17701 cttatctatt gttaaccatg ttccacgtga acccatttgc acgtaaatcc ccttgctagg
    17761 ctgatcaacc tttagaacct tataggttcc tgaaacgaca aaataatcac ccacctgcaa
    17821 aatctgattt ccagcaatac gtcctttatg gtccgtttcg tggagtggag ctgagtctat
    17881 ccagtttaag gaggttggct ctccaccggc taattcactg cttgcaatca tgttctgagc
    17941 gacctgatcg acccgaaaaa caccaggaaa ggctacagta tctccaacct tgataggagt
    18001 ggtcgccaca ggctttggtt tatctataga ggcttgacta tgttgctgag gctgaaccgg
    18061 caatttgtga attggaatgt agcgatgatt tcctgaatga ccgatatagc tgagccattc
    18121 atagccatca gcgacaaggg tttgatcata gtgcactaac tgtccagtat gatagtaagc
    18181 taaatcagga cttgctaatg tagcttcagc ctttatagga ctttggcttg aaaaataata
    18241 ggtaccactt ttagctagac gagttgatcc tgcttgagaa gcatgtaaca tttgtgtgtg
    18301 gctggtagag ttgtgatcca gatccttgaa gtgaatgtaa ccacttacct gatgcttatg
    18361 aatctgtcgt ttatgatact tttcaggtcc ctgtccggca ttatagttgt attcctcaat
    18421 aataacagtg tcaccattga cctctgctac ccaggcgacg tgtccatata gggcatgtga
    18481 ctggttaaag cccttatccc accaagcaac agcaccaact ctaggtgtat gatcaacatg
    18541 atagccttgg tgtttagcta tacgtcccca gctttcaaca ttaccatagc ctctaggcag
    18601 gctgaatcca tttgaggaat gcagtcggaa tgctacaaaa gaagtgcatt gacgtaagta
    18661 catgttccaa ggatcagctc cgaagccctg tttccactta cttggatagt tatcccctaa
    18721 aacagcagcg tgtacgatac ctgactgacc ttgtgaaatc gttgttgtgg cagaggatat
    18781 tgcaccatta ccacctaaaa ggattgctcc tgaagctaac aattgataga cttttttcat
    18841 taattacctc ctgtaactta ctattcgcaa gaaagaggac aaaaatgtcc ttgatttaaa
    18901 aaaatgtaag gaaaaatatt ttagcctcaa aatactgttg gtgctcccta gcttccaaga
    18961 gccaataggc aagcccatct ccagcttgcc tgctccctgt agctaaaagc aatttatagt
    19021 aacactagca cctcatctga agaggcaggc tgtggtaatt aatgccaata atctgtaaaa
    19081 agagacagca ggtatggtta tatgagctat gatggttata ttctataaag cttatttttt
    19141 agcttcgggc tttctttggt gattagttat ttatataaac gaacaattat gctaaaatat
    19201 gtttataaaa ttcgtgttat gaggtgtgtg atgaagcttt tagttatcgg ttcaggtggt
    19261 cgtgaacatg cgattgctaa gaaattgtta gagtcaaaag gcgttgaaca ggtttttgtg
    19321 gcacctggca atgatggcat gacccttgat ggcatagaac gggtagatat tgatatttcc
    19381 gaacattctg ctttgattgc ttttgcaaag accaatcata tagcctggac ctttgtggga
    19441 ccagatgacg cattagcggc tggtatcgtt gatgagttta accagtctgg cttgaaagcc
    19501 tttgggccct ctcgtttagc agcggagctg gagtggtcaa aggactttgc taagcaaatc
    19561 atggtcaaat acggtattcc aacagcagcc tatggcacat tttctgattt tgcaaaagcc
    19621 aaggcctaca tcgaggaaaa gggcgcgcca attgtggtta aagcagatgg tttggcgcta
    19681 ggaaagggtg ttgtcgtagc agagactgta gagcaggcag ttgaggcggc gcgtgacatg
    19741 ctcttggata ataaatttgg tgattcaggt gcgcgcgtgg tgattgagga atttttagct
    19801 ggtgaagagt tctctctctt tgcctttgtg aatggcgatc agttttacct catgccgaca
    19861 gcgcaggacc acaagcgggc tcttgatggt gacaaggggc caaatacagg tggtatgggg
    19921 gcttatgcac cagtgcctca tctttctcaa agtgtggtgg atacagcagt tgagaccatt
    19981 gtcaagcctg ttctaaaagg gatgatgaca gaggggcgtc cctatcttgg aatcctttac
    20041 tgtggcttga ttttgacaga agatggacca aaagtgattg aattcaatgc tcgctttggt
    20101 gatcctgaga ctcaggttat ccttcctcgc ctgacctctg attttgcaca gaacattacc
    20161 gatatattag agggcaacac agctaatatc acatggtcag acgagggagt gacgctcggc
    20221 gttgtccttg cttcaaacgg ttatccgctt gcttacaaga aaggtgtgct tctgccagca
    20281 aagaccactg gcgacatcat tacctactac gcaggggtta agcttgcgga aaatggcaaa
    20341 gcactgctgt caaatggtgg acgtgtctat atgctggtca ccacagcagt taccgtccca
    20401 gctgcgcaag aaaaaatcta taccgaactt gctcagcaaa ataccgaagg attattctac
    20461 cgaaacgata ttggaagaaa agcagtaaaa taaattagcg ctagctcaag ctaccgaagg
    20521 tcgctatgat gacaatgact tattatcggt gagcaaaagc gagcctaaca cgatactttt
    20581 cgccgtagcg caaagagtga caaggtcact cgggggaact tgaaagacct tgggctttca
    20641 agttagtcat gagacaccta tggtggctgt tgacgccccc ccccacttaa gaaaagtatc
    20701 aaaaaccttt aaggagaaag tatgaaacca attatctcta tcatcatggg ctccaaatct
    20761 gactggacca ccatgcaaaa aaccgccgaa atcctcgacc agtttggcct tgcctacgaa
    20821 aaaaaagtgg tctctgccca ccgcacgccg gatctcatgt tcacatacgc tgagaaagca
    20881 cgcgaacgtg gcattaaaat catcatcgct ggtgctggcg gagcagccca tctccctgga
    20941 atggtcgctg caaagacgac acttcctgtt atcggcgtac ctgtcaaatc gcgtgctctt
    21001 agtggtcttg attcgctgta ttcaattgtg cagatgccag gtggtgtgcc tgtggcaact
    21061 atggccattg gagaggcagg agcaaccaat gcagcactga ctgctcttcg gatcctttca
    21121 attgaggatg aaacaatcgc agagcagctc agccatttcc acaaagagca aggacggatc
    21181 gcagaggagt caacccatga actcaactaa aacaattgga attatcggag gtggtcagct
    21241 gggacagatg atggcgattt ctgccattta tatggggcat aaggtcatta cactggatcc
    21301 agcagcggat tgcccagcct cgcgcgtgag tgaggttatc gtggcgcctt atagtgatgt
    21361 ggaggcgctg cgtcaattga ccgagcgctg tgatattttg acctatgaat ttgaaaatgt
    21421 ggacgctgac gcccttgata cagtggtaaa ggaggagcag ctgcctcaag gaacagagtt
    21481 acttcggatc tcgcagaatc gtatttttga aaaagatttt ttagccaata aagcaagcgc
    21541 ggcagtggca ccctacaagg ttgtaacctc tagcctcgac ttggaaaacc ttgacttttc
    21601 gaaaaaatac gtcctcaaga cagcgacagg tggctatgat ggacacggtc aagtcgttat
    21661 tcgctccgaa gcagaccttg aagaggctaa taagttggct aacactgccg agtgcgtctt
    21721 ggaagaattt gtcagctttg accgagagat ttccgttatt gtatctggca atggcacaga
    21781 tgtcactgtc tttcctgttc aggaaaatat ccatcggaac aatatcctgt caaaaaccat
    21841 tgtcccagct cgcatttcag aagcagttag cgctaaatcg caggctatgg cggtgaaaat
    21901 agcagagcag cttaacctat ctggcaccct ctgtgtagaa atgtttgtgg caggcgacga
    21961 gattttggtc aatgaaatcg ccccacgtcc ccacaactca ggacattact ccatcgaagc
    22021 ctgtgatttc tcccagtttg acacccacat tttaggtgta ttaggccagc cattaccagc
    22081 tgtcaaactc catgccccag ccattatgct caacgtcctc ggccagcaca tggaacaagc
    22141 ccaacgctac gccacagaaa accctagcgc ccacctccac ctctatggta aaatagaagc
    22201 caagcacaac cgcaaaatgg gacacgtgac ggtgtttaac agtcaatcag atgaggttga
    22261 agaattttag gaggaattaa tcctatgata aaaatcattg ttcacgcttt tattgaaaat
    22321 ggtgaaacag gtgttgttga agttgtcttt gcttcggaaa accaagaatc catttctgaa
    22381 aaaatgacgg agctacaaaa gcaatatcca aacgattacc ttgctatcta tgatttacca
    22441 ctagatacag acctatcgca attggcccac tatccgtcaa tagcgatagg caaaggggag
    22501 tttgagtagt taaggaagat tagtatttcg gattgagtgt tattgggaca atttatggct
    22561 atgcctttca aaagattggt catgatgttg agcatgttgt gagaattgag aatcgtaatc
    22621 agatttcaga agttggtaaa tgacttaatg gataattcta gatactgatc tcgagcaatc
    22681 ataagagaaa tgttgaaatt gtagcttctg gaggtgtaga actcaaaaat tatcgtggtg
    22741 agatatttcc atataaaact tctaagcgta tttcgtctag attgataaca tatagatagg
    22801 tttgtacata atgaacttac tagatgcatc atgacaaagc agatctttta tatacatgca
    22861 aagaggttta caatattggt atagtcaact attgatgccc taacttttaa tcacaatata
    22921 gaaattattg cgaatagact ttaaaagcat tactattaac tatgtagaaa ggaaatgagc
    22981 gctagaattt tcaaactgaa cctgagcgga aagctcggaa tttagataaa tttcctcgga
    23041 cgtaaatgtc cgtctttagc tttctaaaat tcagttgctt tctggctgtt cttggtatct
    23101 taattatgct aaaccgttat tcacgccctg agatggcgaa gatttggagt gaagagaaca
    23161 agtaccgtgc ttggttggag gtggaaatcc tcgctgatga ggcatgggct gagttgggtg
    23221 agattcccaa ggaagatgtg gcgaagattc gcgccaatgc gagttttgac atcaatcgta
    23281 ttttggagat tgaagaagag acccgtcacg atgtggtggc ctttactcgt gcggtgtctg
    23341 aaacgctcgg tgaggagcgc aagtgggtcc actatggctt gacatcgact gacgtggtgg
    23401 atacggccta tggctatctc tacaagcagg ctaatgacat tatccgtcgt gaccttgaaa
    23461 actttaccaa cattgtggct gagaaggcta aggagcacaa aatgactatc atgatggggc
    23521 gtactcatgg tgtgcacgcg gagccaacga ccttcggtct caaattggcg acctggtaca
    23581 gtgaaatgaa gcgtaatcaa gagcgttttg agcatgcggc tgctggtgtt gaggccggta
    23641 aaatctcagg tgctgttgga aactttgcca atatcccacc atttgttgag gagtatgtct
    23701 gtggcaagct aggcattcgc ccgcaggaaa tctcaactca ggtcttgcca cgagaccttc
    23761 atgccgagta cttcgcagtg cttgctagta tcgcgacatc aattgaacgc atggcaactg
    23821 aaattcgagg cctgcaaaaa tctgagcaac gtgaggtaga agagttcttt gccaaaggac
    23881 aaaagggaag ctctgccatg cctcataagc gtaacccgat cggctctgaa aacatgacgg
    23941 ggcttgcgcg tgtcattcgt gggcacatgg tgacagccta tgagaacgtg gcgctttggc
    24001 atgagcgtga tatttcgcac tcgtcagcag agcggattat cacaccagac acgactatcc
    24061 tcatcaacta catgctcaac cgttttggca atatcgtcaa aaatttgaca gtctttccag
    24121 aaaacatgac tcgtaacatg aactctacct ttggcttgat ttacagccaa cgtgtgatgc
    24181 ttaagctgat cgaaaaaggc atgacgcgtg aggaggcgta tgacttggta cagccaaaga
    24241 cagcctattc atgggacaac caagtggact tcaagccgat ccttgaggca gacgaaaata
    24301 tcactgcaaa attaaggcaa gatgagcttg atgagctctt caatccagct tattatacca
    24361 agcgtgtcga tgctattttc gaccgattag gattatagga agaaaacagc gcgtcttttt
    24421 agactgtagc taagcccaga tttgtttaaa aagtcttgaa aatgaattcc tcggagctaa
    24481 ttctcaaaat gaagaatagt atttcaagag aggctgtcac tagctatatc gcttaagaaa
    24541 atgctctaaa atagacattt tttcaatctg agaaggcaat aggccttctt tttttctaaa
    24601 aatacagaaa tgttattata gaatggagtc aaaaaattaa taattaatta aattatgtga
    24661 tataatgaaa gaaatagtgt cttgaagagg gaaacatgtt agacaatttt ggtgaaaagg
    24721 tgagagacct tcggtatcag aaaaaaatta ccagagagga tttatgtgga gatgagtcag
    24781 aattatccat tcgtcaattg gcacgaatag aactgggcca atcgattccc agcctatcaa
    24841 aggtggtttt tattgctaag gctttggacg ttagtgtcgg ctttttgaca gacggagagg
    24901 atttggagct accgaagcgc tataggagct taaatatttg attttaagaa caccgaccta
    24961 tatggacgat gacaaattaa agctgcgaga agagcaattt gacgaaattt ttgaagatta
    25021 ttatgaccag ttgccagagg aagaaaagct tgtggtggat tgcttgcagt ccataatgga
    25081 tacgttatta accgagaata tcaattttgg agttgggtta ttacaggaat actttgaaca
    25141 aacaaaaagt aagactcaat ttagagagaa tgatctcatt cttattgagc tgtatttagc
    25201 gtacctcgac attgcaggaa tgaatggaga gtattcagat aaaggattct atgattcttt
    25261 gttagacatt ttgttaaatc agtttgaaca ttttgaatta gaggaattat ttattgtcaa
    25321 taaaatagct ataggaattt cctcgttgag catcaaaaac aataagccgg agattcttga
    25381 gaaggttatt gtacttagtc aaaaaattat cctcaagact caggatttta atagaatgcc
    25441 tatcttaaat ttgatagagt ggaaatatgc tctaatgaag aaaaaagaca tagaaatggc
    25501 caaaaaatgc tatgctaagg catgcctgtt tgctcaatta acaggagatc agtatttgga
    25561 aaagaaattg agagaagaat ggggtaaaga tataaaacga tatcaatagg acaaaaatgt
    25621 catttttatc aaaaatggaa taatatataa tctttatata acaaataatt gattaaagga
    25681 gttccattta tatgtttaaa aaataccaat actatctgtt tttagctgct ttatttctac
    25741 ttcattctgc ccaattactt agtgatattg actggtggcg tgttggttaa agctaaatca
    25801 tctatttatg ctataatagc tctatgacaa gaattttaga taatgatctg ataggcgatg
    25861 aaggatctgt tgagaggaca ctacgtccac agtatttacg tgagtatatt ggtcaggata
    25921 gggttaaaga ccagctgatg atttttattg aggcagccaa gaggcgtgag gaatccttgg
    25981 atcatgtcct gttatttggt tccccaggct tgggtaaaac aacgatggcc tttgtcattg
    26041 ccaatgaatt gggagttcat ctcaagcaga cctctggccc agccattgaa aaagctggtg
    26101 atttggtggc aattttgaat gatttagagc caggagatgt cctctttatt gatgaaattc
    26161 atcgtatgcc gatggctgtt gaggaaatct tgtacagtgc catggaggat ttttacattg
    26221 atatcatgat tggcgctgga gacactagcc ggagtgtgca tttggagctg cctcccttta
    26281 cattaattgg agcaacgact cgtgcaggca tgctgtcaaa tcctttgagg gctcgttttg
    26341 ggattactgg gcatatggaa tattatcaga cagctgattt aacagagatt gtggagcgta
    26401 cagctgatat ttttgacatg acaatcaagc atgaggccgc ttatgaactg gcacgcagga
    26461 gtcgtggaac ccctcgtatt gctaatcggc tgttaaaaag ggtgcgtgat tatgctcaaa
    26521 ttatgggtga tggaatgatt acgactcaaa tcacagataa ggctctaacg atgttagatg
    26581 tggatcaaga aggtttagat tatgtggacc aaaagattct tcgtaccatg attgaggtgt
    26641 accaaggagg gccggttggt cttgggactc tatctgtcaa tatagcagag gagcgagata
    26701 cagtagaaga catgtacgag ccttatttaa ttcaaaaggg ttttatcatg cgtaccagaa
    26761 caggccgagt tgtcaccgaa aaagcctatc agcacttagg ctatccctat gaaaaaacca
    26821 ttaagacata aatagctatg taagacttga ttcctttgtt tttaccggtg tcaagtcttt
    26881 tgtattgtca atagcttact gagtaaaaaa gtaaaacgat gtgaggtgag gggtgattgg
    26941 tcagggaagc agaggtgctt tcactagaca aagcattaaa aaacattttt agatcaattg
    27001 aacgaaaatt ataagagcga tttctccttt tggccctata attttgctat aataggtaaa
    27061 aggagttttt catgaaaaaa gtatgctttg tttgtcttgg aaatatttgt cgtagtccta
    27121 tggccgaatt tgtcatgaaa agtatggcca gtcctgatga gctacaggtg gagagtcgtg
    27181 caacctctgg ctgggagcat ggcaatccaa ttcatcatgg gacacaatcg ctattacagc
    27241 aatatcagat tagctatgat accaagaaaa cctctcagca aatcaccagc tttgactttg
    27301 aagcctttga ctatattatc ggaatggata gccataatat cagagatttg aagcaaatgt
    27361 ccaagcatca gtgggattcc aagatccatc tttttattga aggaggcgtt ccggatcctt
    27421 ggtatacagg agattttgaa gaaacctacc gcttggttaa agcgggctgt cagcattggt
    27481 tgagtcaaat cagcgctgaa catgaatcac atgtggaaat agatgagtaa tagtaatgaa
    27541 agcaataata aataacattc aaaaatggca gatcactcgg acaaagctag agattatttc
    27601 agtccttgtg attattgtct gtggattgtc ggtttttacc ttgaccatat cctcaaaagc
    27661 aagcttgacc tatgacaatg ggcaaatcaa gtacaccggc tatgtcctta atcatagaat
    27721 gaatggtaaa gggaaattgg tttaccctaa tggcgatacc tatgttgggg attttaataa
    27781 aggtgtcttt gatggagaag gaacgtttac agctagtaca gggtggtctt acagcggaca
    27841 atttaaaaaa ggtcaggctg atggcaaggg tactttgaag gcgaaggatt caaaggttta
    27901 caaaggaacc tttaagcagg ggatatttca aaaatgagga taaaatggtt ttcgtttatt
    27961 agggtaacag gtcttttgct ggtgttgctc tatcactttt ttaagcatac tttttcagga
    28021 ggctttgttg gcgttgacat cttctttact ttttcaggct atttgattac agccttgttg
    28081 attgatgaat atgtctcaaa acaaaccatt gatgtggttg ctttttttag aaggcgtttt
    28141 tatcgtattg taccgccgct tgtcttgtta attctcttga caattccctt tactttttta
    28201 gtcaaaagtg acttcattgc tggtatcggt cagcaaatag cagctgccct agggtttaca
    28261 acaaatagtt atgagctact gacaggcagt agctatgaaa gtcaattcat tccgcatctg
    28321 tttgtgcata cctggagctt ggccattgag gtgcattttt atttgctttg ggggctgttg
    28381 gtttggttat tagctaaaaa aggctacagt cagaagaaat ttagaggcat tctgttttta
    28441 atttcttccg cagtgttcac gcttagctac ttcagcatgt ttatcagagc cttctttgta
    28501 tcagattttt cttctgttta cttttcaacg ctttcacaca gctttccttt ctttttagga
    28561 gcgatgtttg caaccatgac gggaattaag gacacgactg ttcgctttca aaagaatgtt
    28621 aagctgtggc caaggctaca tgttattgga gtgatggctg gcgcttttgc tctgttgttg
    28681 tttctaacgc ttgtgttaga ttttaaccat atctttacct atcttttcgg ttttgtctta
    28741 gccagtcttt ttgcttcggt aatgatttat gctgcgcgtg ttttgagcga tcaaacacca
    28801 acctggcagg aaccactgct tgtgacctat cttgcggata ttagctatgg gatttattta
    28861 ttccattggc cattttacat tatttttaca cagctgatgt ctaactggct ggcagtgatc
    28921 ttaacggttt tcttttcagt agtgttttca acgctttctt attacattat tgagcctttg
    28981 attcaaggca agacaccaca gctttttggt ttagcaattg attgtaatcc ctataagaaa
    29041 tggttatcag ggcttgcttt aggactcttt ttgttgatgg ttggtacctg tttgacagca
    29101 ccaagggtcg gtaattttga gacccagctt ttagtagatt ccttgcagca atctcaaagt
    29161 aatctcaata agacacatac tttggcagca ggagatgcgc atgctcttag tgatgttagc
    29221 attattggtg actcagttgc cttgaggtct agtgacgctt tttcaaaatt aatgccgact
    29281 gctcaactag acgctgctgt cagccgcaat ttcagtgaag cctttgagct ttttgaaaat
    29341 catatccaat ccaagagctt atcaaaaaca acggttttag ctgttggtgt taattctctt
    29401 tataattatg cgcaggatat tcaaggcttt atttatgcac taccaaaggg gcatcgcttg
    29461 gtgattgtgt cgccctatga tgctaagaat gcagcacagg tagcagaggc tagagagcat
    29521 ttgttgcagc tagctaaaaa atatagctat gtaacagttg ctgactggta caaggcggca
    29581 gtcgaaaatc ccaatatctg gtatggtagt gatggggtcc actacaataa cgacgccaaa
    29641 ttaaaaggtg ctgacttata tgtctcaacg attcaggcgg ctgttgagcg agcagcaaaa
    29701 aaagatgcta aatagtggtg ctaacaacaa tttgttaaga attaataacg aaggcttggt
    29761 cttacaaaca gatcaagcct tttcatgatg tgatttttag atcgtcttgc gccctttagc
    29821 gcgagataaa gctccacctg ttagacagtg tcattattgg ctgttattgc tgacggtgac
    29881 gtgcttttaa aaacggatca ttaaataatt tagcctgatc taaaaaagaa agcgctttcg
    29941 gaacaaagtg aatgcgtcag ccattatttc agaaaaaatc caccaagcca aaccccttgt
    30001 tatcaaagag tttcggaaat tgattgaaaa aacatcacaa ttttattgtg aaatgattta
    30061 caaaatgcca aaaaatgata taatattttt gtaaacaaaa ttgtgaaact tttaacaagg
    30121 taaaggagtc tcaaatgact gaaaaaaata gtactgttga aacaacatct gttgccgcaa
    30181 caattgacgc tcttgttcaa aaaggtttag tagcgcttga taaaatgcgt cagttaactc
    30241 aagaacaggt tgactacatt gtagcgaagg cctctgttgc tgctttggac gcacatggtg
    30301 agttagctaa gcatgcctat gaagaaactg gtcgcggagt ttttgaagat aaggctacca
    30361 aaaacctttt cgcatgtgag cacgttgtta ataacatgcg tcaccaaaaa acagtaggta
    30421 tcattgaaga agacgatgta acaggtttga ccttaattgc tgagccagta ggtgttattt
    30481 gtgggattac cccaacaact aacccaacgt caacagctat ttttaaatct ttaatctcct
    30541 taaaaacacg taaccctatt atttttgcct tccacccatc agctcaagaa tcatcagctc
    30601 atgcagcacg cattgttcgt gatgcagcca ttgcagcagg agctcctgag gactgtgttc
    30661 aatggattga aaccccatca ctagaagcaa ctaacgctct gatgaatcat gatggtattg
    30721 caacaatcct tgcaactggt ggtaatgcta tggttaaggc agcctactca tgtggtaagc
    30781 cagctcttgg ggttggtgct ggtaacgtgc ctgcctatgt tgaaaaatcc gctaacattc
    30841 gtcaggcagc acacgatatt gtcatgtcta aatcatttga caatggtatg gtttgtgctt
    30901 ctgagcaggc tgttattatc gacaaggaga tttatgacga gtttgttagt gaatttaagt
    30961 cttaccacac ttactttgtc aacaaaaagg aaaaggctct gttagaggaa ttctgctttg
    31021 gtgctaaggc taacagtaaa aactgtgcag gtgctaagct gaaccctaat attgttggta
    31081 agccagcagc ttggattgct gagcaggcag gctttacagt accagaagga acgaatatcc
    31141 ttgcagcaga atgtaaggaa gtttctgaaa atgagccatt aacacgtgaa aaattgtcac
    31201 cagttatcgc tgttttgaag gctgaatctc gcacagatgg tgttgaaaag gctcgtcaaa
    31261 tggttgaatt taacggactt ggtcactcag ccgctattca tactgctgat gcagacttag
    31321 ctaaggaatt tggaacaaaa attcgtgcta ttcgtgtgat ttggaattca ccttctacat
    31381 ttggtggtat cggtgatgtt tataatgcct tcctaccgtc attaacattg ggctgtggtt
    31441 cttatggacg taactcagtt ggtgataatg ttagtgctgt aaatctcttg aacatcaaaa
    31501 aagtaggaag acgtagaaat aatatgcaat ggtttaaagt tccttcaaaa acatacttcg
    31561 agcgtgattc aattcaatac cttcaaaaat gtcgtgacgt tgagcgtgtg atgattgtta
    31621 ccgaccacgc tatggttgag cttggcttct tagatcgtat catcgagcag cttgaccttc
    31681 gtcgtaataa ggttgtttat caaatttttg cagatgttga gccagatcct gatatcacaa
    31741 cggttatgaa aggtactgag ctgatgcgta ccttcaagcc agatacgatt atcgctcttg
    31801 gcggtggttc tccaatggac gctgcaaagg taatgtggtt attctatgag caaccagagg
    31861 ttgacttcca tgatcttgtt caaaaattca tggatattcg taaacgtgcc ttcaagttcc
    31921 ctgagcttgg taagaaaaca aaatttgtgg ctattccaac aacctcaggt acaggatcag
    31981 aggttacacc gtttgctgtt atctcagata aggccaacaa ccgcaagtac ccaattgctg
    32041 actattcatt gacaccaacg gtagccattg ttgacccggc gttggtgctt acagtaccag
    32101 gcttcattgc agctgataca ggtatggacg tgttgaccca cgcaaccgag gcttacgtat
    32161 cacaaatggc taatgacttt acagatggtt tggcccttca agccattaag attgtctttg
    32221 aaaaccttga aaaatctgtt aaggaagctg actttgagtc acgtgaaaaa atgcataatg
    32281 cctcaacaat ggcaggtatg gcctttgcta atgccttcct gggtatttct cactcaatgg
    32341 ctcataagat tggtgcacaa ttccatactg ttcatggacg taccaatgct atcttgcttc
    32401 catacgttat tcgttacaat ggtacccgtc ctgctaaaac agcaacatgg cctaagtaca
    32461 attactatcg cgccgatgaa aaatatcaag acattgctaa gttgctagga cttccggcat
    32521 ctactccaga agaaggtgtt gaatcttatg ctaaagctgt ttatgatctt ggctgtcgct
    32581 taggcattaa gatgaatttc agagatcaag gaattgatga ggaagaatgg aaggcacaca
    32641 ctcgtgagct tgcttatctt gcctacgagg atcaatgctc acctgctaac ccacgcttgc
    32701 caatggttga gcacatggaa gaaatcatga atgatgctta ttatggttac gcagagcgtc
    32761 caggacgtcg gaaataatat caatcattaa tagtaaaaat aggagctgct tggcttctat
    32821 ttttttatct agctatgaaa agggctgtgt tagatgaaaa agtcggcagt gccttgtgtt
    32881 gagatagctt aactcagggg tagtttctca gatatcatat aaagctttta agacaatggt
    32941 tttacagagc attccatcag agggggaagc ttcatttgcc atattcataa agtggctgat
    33001 agttacgact tagctgcact tagcaattag ctgaagaaaa taacatgttg cgtctatctg
    33061 atgagcttta ttttctaata aaacaaggag tgattgcttt tttaatgatg ttaatagcgt
    33121 taaaaacctt tatatatcaa acaaaaacca aaataatggt attgtcagac tttttctaaa
    33181 attacccttt attaattgac aaagagggtg taaaaaatta tactaaaaat gtaatcgatt
    33241 acattttcta gactaaattt ggagacgttt tatgaaagca gctacatatg ttgctccagg
    33301 tcagctggag cttattgatc aaccaaaacc agagattctt gctccgacag atgctgtggt
    33361 tcgtttattg aaaacaacaa tctgtggaac agacttacat attttaggtg gagatgtccc
    33421 agagactact catggtacca ttttaggtca tgaaggtatt ggtattgtcg agtcagtcgg
    33481 ctctgcagtg aacaacttta aggtaggtga taaggttatt atttcctgta tcacagcctg
    33541 taatacctgc tattattgta aaaaaggaat tcctgctcat tgtgaaagcg gtggctggat
    33601 tctagggcat ttgattaatg ggacacaagc agagtatgtt catattcctc aagcagatgg
    33661 cagtctttat catgctccta aaaccgttga ggatgatgcc ttggttatgc tgtcagacat
    33721 tttcccaact tcctatgaaa taggcgttca gtctgcaaag gtaaagccgg gtgatacagt
    33781 gtgtatcgtt ggagcaggtc ctatcggact agcagctctt ttaacagcac aattttattc
    33841 accagctaag ctgatcatgg ttgacttgtc agaatcacgt ttagaagcag ctaagcgctt
    33901 tggagcaaca gatacgattt gctctggtga ccttgatgat attgtcaaaa aagtccatga
    33961 attaactgat ggtcgaggtg ttgatgttgc cattgagtgt gtaggctatc ctgctacctt
    34021 tgatatttgc caaaagatta ttgctattgg cgggcatgtt tctaacgttg gtgtccatgg
    34081 aaaaccagtt agtttggacc tacaggacct atggatcaaa aacattacaa tgtcaactgg
    34141 cctagtaaac gctaatacaa cagaaatgct attgaatgtg ttgaaatctg gtaagattga
    34201 tgcaactaag atggtaacac atcactttaa gctgtcagag gttgaaaaag cctatgaggt
    34261 ctttaaaaat gccggcagta ataacgccct taaagtgatt attgaaaatg acattacagc
    34321 ctaaaggaat aaggtataaa tagataaaag tgacaacagc atttggaatg gtctagatgc
    34381 tgttttttag ccaacttaac tggttaagtt tattttcaga aaactttcaa gaaattggtt
    34441 gacaaacctt gtgaaaaagt atacaataca aattgtaaac ggttgcaaaa atagataaac
    34501 cgagacttag aaattggagg catcctatga aggctgtagt tgttaaccaa accagcagtg
    34561 gtgtagaggt tgtagagcat gatgtaccat caatcggtca tggagaagct cttgttaaag
    34621 tagaatattg tggcgtatgt catactgact tgcatgttgc gcatggtgat tttggtcagg
    34681 ttccagggcg tatcctcggt catgaaggta tcggtattgt cgaaaagcta ggtgaaggcg
    34741 ttacctcctt aaaggttggt gatcgtgtat caattgcttg gttctttgaa ggctgcggtc
    34801 attgtgaata ttgtacaaca ggtcgcgaga ctctatgccg ttcagtcaaa aatgctggct
    34861 attcagttga tggtgggatg agtgagtatg cagttgttac agctgactat gctgtgaaag
    34921 tgccagatgg tcttgaccca gctcaagcat catcaattac ctgtgcaggc gttacaacct
    34981 ataaggctat caaagaagca ggtgccgctc caggacaatg gattgttatc tttggtgccg
    35041 gtggacttgg taacctagct gttcagtatg ctaaaaaggt tttcaatgct catgtcgtag
    35101 cagtggacat taacaatgat aagctagagc tggccaagga ggttggagca gatatcgttg
    35161 tcaatggtaa agaaatcgaa gatgttgccg gctatatcca agaaaaaaca ggtggtgctc
    35221 atggcgttgt ggtaaccgct gtttctaaag tagcctttaa ccaagctatt gatagtgtgc
    35281 gtgcaggagg aactgttgtt gctgtaggac ttccatcaga atacatggaa ttatctatcg
    35341 taaagactgt cctagacgga atcaaggtag tcggatcact tgtgggaact cgtaaagact
    35401 tggaagaagc ctttgccttt ggtgcagaag gtctggttgt gccagttgta gaaaaggttc
    35461 cagttgagac tgctccagaa gtctttgacg aaatggaacg tggtctcatt caaggaagaa
    35521 aggtattgga tttcacgctt taaggctgat ttcagaaaaa gtcagcagcc agacaagctg
    35581 attgtcccaa atgatgaata aagtccttag aattaatttt ctaagggctt ttttggtgaa
    35641 actaactggt aaaaaaagct tggtatctaa agatgtaaaa gagccagcta gttattaata
    35701 ccatgattgc cccttgaaag acagtaccag agaaagttgg acatattgta acctctgata
    35761 gagatactgg gtttgaacaa tattagagat taacacagga actcaatcta gaagtttatt
    35821 tctctgctcc tcacacccct tgataacgta ggacaaatga aaataccaat gggttaatca
    35881 aagagtagtt tcctaaagga actgacttga ctgatattga gagctctatc atataagagt
    35941 gggaagataa atgaaatgat cgttctagaa gatgtcctaa ctggaaacta ccttataaac
    36001 tcttttatgg aaaagcgttg cacttaattt gacaattcgt cttcacaaat tttaggaagc
    36061 actgtaggaa aaaagaataa tgacataaca tattgctaaa aacatgggtt ataagctaaa
    36121 ttattatcta cgtttttagt aacaaggtag tatgatttaa aatatagatg aaaaatgttg
    36181 tgtcccgaat aagggaagtt ttttaggata cgatacttgt acattataat ttatttataa
    36241 aatcttttag gtggatttat gaaagaaatt gtaagaagtc atagattgtt atatgtaata
    36301 gtagcttttt ttagtgtaat cagtgcattt ttaatgacct tattttctat tcaactggga
    36361 aaaatactag atagtatatc taattcaagt agtgaattat tgtttcagat agtagtgtgt
    36421 gtatgtacca taatggcatg gtttataatg atatggtcct attcttattt taagagttat
    36481 tatgtaaaaa aggtcatttt agatttaaag gagaggcttt ttataggtta tttattacgg
    36541 gaatttaatg aaattgatac ttgtgatcga tataattcgg attttctaaa caatgtaaca
    36601 aaaaatattg atataattca ggagaattta ttggttccta gagtggctgt gattgttgat
    36661 ctggcttcaa tggttacgag tgtagtagct attgtactta tagaatggcg attggcccta
    36721 gtatttttat tgctttctat tgtaactgtt tttctatctc aaattcctgg aaagttaatg
    36781 agtaaagcaa ctcgatatta ttctgaaaaa agtaatcact atttagcaga aatgactagt
    36841 tttattgagg gatttgaaca gattaaatta ttgaatattc aaaaatggat acaaaaaatc
    36901 gaacaaaata ctactttaga atttgaagat tctagacaga aatatcaata cagaaaagat
    36961 ttagcttcaa atacaggaat gtttttgagc ttcttttctc aagtagcctg tatggttgct
    37021 ggtatatttt ttgtaaggaa taatctacta acagttggac tattagtggc cagtattcag
    37081 ttattaaatg gagtgtttgg ccctctacag tctttccttt acaataaaaa tttgatcaaa
    37141 agcacaggta ctattttaac aagtattcaa gaagttctag ataaaacaaa ttttgttaat
    37201 ggttatatag aaaataagac tttttatgaa ggagacatct ccagcatttc gataaataat
    37261 ttaacttatc aagttgaaaa tagaaaaata tttactaatt tttcatttga atttaaaaag
    37321 ggaaatactt atgccattat tggtccttcg ggggttggga aaacaacatt agcaaaactg
    37381 atatta
//
LOCUS       DARYNN010000020        33280 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.020, whole genome shotgun sequence.
ACCESSION   DARYNN010000020 DARYNN010000000
VERSION     DARYNN010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33280)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33280)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33280
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.020"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            132..824
                     /locus_tag="TVB59_000905"
     CDS             132..824
                     /locus_tag="TVB59_000905"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEL1009812.1"
                     /translation="MKKLEALLENSFNIRFDDKRLLETAFTHTSYANEHRLLNISHNE
                     RLEFLGDAVLQLIISEYLFAKYPKQTEGDMSKLRSTIVREESLAGFSRYCSFDAYIKL
                     GRGEEKSGGRHRDTILGDLFEAFLGALLLDKGIEEVRRFLNQVMIPQVEQGTFEKVKD
                     YKTCLQELLQAKGDVVIDYQVISETGPAHAKQFEVAVLVGEDHLSKGTGRSKKLAEQD
                     AAKNALAQLSEV"
     gene            825..4376
                     /gene="smc"
                     /locus_tag="TVB59_000906"
     CDS             825..4376
                     /gene="smc"
                     /locus_tag="TVB59_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEL1009813.1"
                     /translation="MFLKEIQMQGFKSFADKTKIIFDKGVTAVVGPNGSGKSNVTESL
                     RWALGEASAKSLRGGKMPDVIFAGTEHRSPLNYAEVAVVLDNSDAFIKNAQKEIRVER
                     HIYRNGDSDYLIDGKKVRLRDIHELFMDTGLGRDSFSIISQGRVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRKKETQTKLNQTQDNLDRLDDIIYELEHQAGPLERQAKTARQFLAL
                     DADRKQLQLDILVKDIEQDRMEQEAQEKALVALREDLAAYHRKRQSLEAENHRLKTKR
                     QKLSAVAEQTQADLLELTKVISDLERQIDLIKLDLSQKQEKKTEASQRRQQAQEQLLA
                     FQQEHQQKSRQLDEIHQALAEFNTKVSELSQELERFSSDPDQLLEALREDFVGLLQQE
                     ADVSNQLTAIVAQLDKESQAKASQAQEYQVLQEKVNQLSQDTQTALLAYQASQSRLEQ
                     LLADYQELAKTVEALEQDYHQGQTRLFDLLDQKKAKEARRASLVSIQKNHSQFYAGVR
                     AVLQAAGKLDGILGAVSEHLTFDSQYQTALEIALGASSQHIIVADEAAAKRAIAFLKA
                     NRQGRATFLPLTTIKARQLSEVTLKQLRACQGYLGTADSLVTYEPSLVAIVQSLLGVT
                     AIFDTIDHANQAAKQLHYKVRIVTLDGTELRPGGAFSGGTNRHNSTTFIKPELEQIEK
                     ELALLSEQIKESEKAVAAVQADLKAKKAAQADTKLAGEQARLVEQKTQLAYQQLAEKL
                     ADSKELLELLSNRQTGQSSERLLSEKARLEEALQLLADEKSALTSEIEQIKENKDTIK
                     QKKDQLSQELSQARLKERDLLNEKKFEAANQRRLETMIAQGQKELANLETVLSHQVSQ
                     EAIDQLPHLENQLTEANQDKIKTQERFIQLRFEGEDYDARLEELEAQLLKEAKKNEAF
                     IRQQARLEADLEQVIGRLRQHARSLSEELQLSLEEAKEQASPINDTDMAAARQKLQQV
                     QQSIRALGPINSDAIAQFDEVSERLAFLNGQRADLIKAKNLLVDTIGNMDHEVKARFR
                     VTFEAIRDSFKETFRQMFGGGSADLMLTETDLLSAGVDISVQPPGKKLQSLNVMSGGE
                     KALSALALLFAIIRIKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRK
                     GTMAAADSIYGITMQESGVSKVVSVKLKDTQDLTYLS"
     gene            4741..5184
                     /locus_tag="TVB59_000907"
     CDS             4741..5184
                     /locus_tag="TVB59_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009814.1"
                     /translation="MMTVKTNKQRLWLGLIIVIGAIIMVFRLNGKRTEEQQKRDLETS
                     IAKLLVHDYEGVKEVKFTGWGHSRETGSWGTIVIINGENEIGFSFDGLSSLEKIRGIV
                     TDDDTEKMEKPETDTKPRIMDRIDKINKTSLVGVTVIYSKDNQED"
     gene            5186..6475
                     /locus_tag="TVB59_000908"
     CDS             5186..6475
                     /locus_tag="TVB59_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009815.1"
                     /translation="MAISDSSYNELAKQVYNVEPSKAKSNGDLVIVAGKTVKDPITKR
                     QYRVLLVQDNNNDAHKTNDNGMQAMAVAPIVKGDIDTSQVVIAYAGTNAADSRDLDTD
                     WQLLIRGNQDDLVSGNIDGGNFVIAENQLRSAQKFYQQVKRKYPHSALTTTGHSLGAY
                     LALIVAAEHKIPATTFNGPDPVRGMSAEAITWVKANSNMYNNFRINFDGIGNFGAYFG
                     TDDLAISRNVDAMLLSANPLYYHDLGAYRFNQKGQIVDRDGKLIGTQYLVSRAYLTVL
                     ASKKSMSSYNQLKKHWQSTGKGISSSEELFLDAAQGMILGSSMAKAAREGADEALDHK
                     TVADAKLMEVWSAIDFNSFHELPYYEVQALFASYGITYDRFVQDFQDYTQSKVSKLSA
                     LATDFENLNRDIQTVIDSKLETDRQLAGEFRAWQTEL"
     gene            6457..6774
                     /locus_tag="TVB59_000909"
     CDS             6457..6774
                     /locus_tag="TVB59_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009816.1"
                     /translation="MADRIVEEVAIYRKLREMDDAEQDFLRQKRAYQKREDSLSERRH
                     VLNDLINSEYQKMSVFLKRLDLSANAASDFFNELGRLKDQSNAEFHLFLKLGKILNNK
                     SLG"
     gene            6941..7246
                     /locus_tag="TVB59_000910"
     CDS             6941..7246
                     /locus_tag="TVB59_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009817.1"
                     /translation="MLAVSTLSFGSAATARVVSAATAHPAPYPIIDEWNYGVSDNYGY
                     SNDYVKSPNNIGSKSSVTNLWGTVKDRDSQKYGWANSSATKSWNDVRLNTHWNYFTF"
     gene            7313..9295
                     /locus_tag="TVB59_000911"
     CDS             7313..9295
                     /locus_tag="TVB59_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1009818.1"
                     /translation="MKLKLCIVGFFFCLIAAIGLVSINDTQKPIPLPIDGAFSIQGKS
                     NLSNEEVYQTISDLSKEKKVTIYKPVVQNSGQLTYIKFDNTNHEQLKSAPITGMYYTL
                     GKLDSNSLKPLTSTGLQVIYLAYPWQIGGMIQFTGPLRLLLMISIYLTLLVVLFVVRA
                     RQIKEGVIRRSLGLPVHDLRRDYFMSFTFELVMAALLMISYSSFLGSGFFTYSSKLFF
                     SMLLTNLIIFQIIDIITFVLFWLTIKVEKPIEIIKNKAKNSLIFIVWLAVISIIIVVS
                     GVFLRETKASQSKINMQIKHLKPWSAVKDWKRPEFLGIENESVTNGEEANDSGAKYVE
                     IAKALKKLDFIYIKSSSAYVPEYMAASDVTEDFSKQLKSDGITHPEVNKELVYINQTG
                     AKVQNKVNGTNYQSLDNKIATIYIPHKFKENKASIENTVVAEQFTGTNYTKDDLTVQV
                     IPDGQEFFYFNENGSSVPENKDNLPLESVTDSKDNIVVVLDTDKMIENNDFILASNII
                     YNSLFSSEAIKKINDLSASLNFSINPVEVYQTVKLNIQSLEHQIFLSKILQIIICGIV
                     FLLIYQYAQMFVALKQNDYVKKIILGLSKTRIAISSLNYFIVTITMVILLTFMLTGQV
                     ELLYIGIASLMVLIFSTIMSFRKLSEKYTQILKGDD"
     gene            9295..9918
                     /locus_tag="TVB59_000912"
     CDS             9295..9918
                     /locus_tag="TVB59_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1009819.1"
                     /translation="MAIEVLNVTKKFGSKKIFTDLNLTFEAGKSYALIGGSGSGKSTL
                     LNIIGRLEKIDSGKVLVDEQDIWKTKERTFFKTIIGYVFQNYSLIENKTVYDNLRLIN
                     KDKKIIADVLEKVGLSNDYLNQKIYELSGGQVQRVAIARMLMKPRKIILADEPTGALD
                     SEIGKEIINLLLSETAENKYVIIATHDPAVYNKVDVIIDLKDIGSEI"
     gene            9915..10424
                     /locus_tag="TVB59_000913"
     CDS             9915..10424
                     /locus_tag="TVB59_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009820.1"
                     /translation="MKKKAYMTLILLIGILAIFLVGKQVIKKENPNKPTVDLTVYTIS
                     SSDTQKWNKVRQLETEEAIYLIRVKEAASSEEIFSNIIADGAAMGFGVSEEDVKQFNN
                     HLENTIEDSKNNKLIEMEFFDFSNNNKGFVVANFDYGKKEFNAQKKEKKALYKKLYEA
                     FKEKNHQSR"
     gene            10942..11739
                     /locus_tag="TVB59_000914"
     CDS             10942..11739
                     /locus_tag="TVB59_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL1009821.1"
                     /translation="MVKLIATDMDGTFLREDGTYDKERLAALLPKLREKGILFTVSSG
                     RSLLAIDHLFEPFLDDIAIIAENGSVVQYKRDILFADVMTKQQCHDIVEKILANPYYN
                     QSGILFSGQKAAYVLKGATEDYIQKMHYYYENVQLIDCLQDIVDDTVFKASTTFTGET
                     VLAGSDWLNQELSYASAVTTGFDSIDIILKEVHKGFGMDQLCQHLGILPEKTIAFGDN
                     LNDYQMLSFAGQAIATENARPEIKAISDQVIGHCNDSAVLTYLEGLV"
     gene            11740..12567
                     /locus_tag="TVB59_000915"
     CDS             11740..12567
                     /locus_tag="TVB59_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL1009822.1"
                     /translation="MTRIKLLALDLDGTLYNTEKIVSDENKKALAAAKEKGVKVVITT
                     GRPLKAIGNLLEELDLLGEENYSITFNGGLVQRNTGHILDKSALSLAEVYDIHQQLAA
                     VGLPTDVISDGTVYSLSGNDGRRSQYHLASPLLNFVSLKSFAELPKDITYNKIVTVTD
                     PKVLDQQLARLPKTIFEDFEAFKSRDIIFEIMPKGIHKAFGLDLLCQHLGLEAKHVMA
                     MGDEANDFSMLQWAGLGVAMANAVDQAKEVADAVTTLTNDQSGVAEAIWKYILNEEG"
     gene            12567..14024
                     /gene="ftsY"
                     /locus_tag="TVB59_000916"
     CDS             12567..14024
                     /gene="ftsY"
                     /locus_tag="TVB59_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEL1009823.1"
                     /translation="MGLFERLFGKKDKTKVAEQEAATTEVLSEDITSKDTIESEKEAL
                     SDTNAHAVAADVVSRTDDTSKQAELSDEAASEQAEGLDPAARGAFLLEREPELELAAT
                     DDKTLDQAGESLSQHEAMEEAKHDRAKSEHSNESADASTEDQAETNAEYQVAAQAPAG
                     SADQPAEEGQKQETLSAESDQEKYKRSLKKTRTGFSARLNSFFANFRRVDEDFFEDLE
                     ELLILSDVGVHVATTLTEELRYEAKLENAKKPEALKRLIIDKLVAIYEGDGRYNEAIH
                     YQPGLTVMLFVGVNGVGKTTSIGKLAYRYKQEGKKVMLVAADTFRAGAVAQLVEWGRR
                     VDVPVITGPEKADPASVVFDGVERAVAERADILLIDTAGRLQNKDNLMAELEKIGRII
                     KRVIPDAPHETLLALDASTGQNALSQAKEFSKITPLTGLILTKIDGTAKGGIVLAIRQ
                     ELDIPVKLIGFGEAIDDIGEFHSEDFMKGLLEGIL"
     gene            14313..15152
                     /locus_tag="TVB59_000917"
     CDS             14313..15152
                     /locus_tag="TVB59_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEL1009824.1"
                     /translation="MIIKRVLNHNAAISTNHQGLDILLMGKGIAFKKRIGDHIDSEAI
                     EASFVLKNSDNMNRFTELFIAVPQEVVACSERLINLGKIKLGKNLDEILYINLTDHIH
                     SAIERHKQGMIISDPLRWEIRRYYPDEYAIGVKALEVIASELGVALAVDEASFIAMHF
                     VNASLDNPFKEPHRMTEIVSYIEQKVKADFKTELDEVSIDYYRFITHVKLFAQRVLSG
                     MAYDDDETDLLLMVKDKYPEEYHCVRQISHHMKKAYHYQLSSSELLYLTVHIKRLVKN
                     VKE"
     gene            15157..17019
                     /locus_tag="TVB59_000918"
     CDS             15157..17019
                     /locus_tag="TVB59_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HEL1009825.1"
                     /translation="MTYQETAKAIFEAVGGEQNIQEVTHCITRLRLVLKDDKQVVDQK
                     IKLIPNVIGVMRQNGQYQIILGNDVNNYYKAFMTLGQFHETDMSSSAGQKQSMIEGLI
                     ETIASVITPLIPALLGGGMLKVVGILVPMLGLAGTDSQTVAFINFFGDAAYYFMPIMI
                     AYSAAARFKVTPVLAATVAGILLHPAFVTMVATGKPMALFGAPVTPASYGASVIPILI
                     MVYLMQYIEREVNRFVPSVMKSFLQPTLIIFISGFLALVVIGPLGVIIGQGLSNSLLA
                     IYHIAPWLALAILGAIMPLVVMTGMHWAFAPIFLAASVATPDVLILPAMLASNLAQGS
                     AAVAVACQSKQKQTRQVALAAGLSALLAGITEPALYGITLKFKKPLYAAMISGGLVGA
                     YIGFVNIASYTFVVPSLIGLPQYISPTSSANFTNALIAAGLTIALTFTLTWFFGIDEE
                     VDQEGSADSDSTPVKSGLSAKQSIYAPMVGTVLPLSEVPDETFSSKLLGEGLAILPNE
                     EYVYAPFDGEVITLFPTKHAIALKNAKGVDVLIHVGIDTVELKGQGFEQLVKAGDTVK
                     QGQPLLRIDLELIGSKGYSLVTPFVVTNSSEQLEIIVNDNKEHITQHDVALVIL"
     gene            17046..18467
                     /locus_tag="TVB59_000919"
     CDS             17046..18467
                     /locus_tag="TVB59_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000643228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEL1009826.1"
                     /translation="MVCFPKDFLWGGAVAANQVEGAYLTDGKGLSVQDVLPEGGLGDY
                     TAEPTAANLKLEAIDFYHRYKEDVALFAEMGFKVFRTSIAWSRIFPQGDETEPNEAGL
                     QFYDDLFDELIAHGIEPLVTLSHYETPLHLAKVYNGWTDRRMVGFFERFATTVMQRYK
                     NKVKYWLTFNEVNSILHMPFTSGAIMTPKEKLTPQELYQAIHHELVASASVTRLARLI
                     NPAFKIGCMILAMPAYPMTSDPRDILAAKQFEQRNLLFSDIQVRGKYPSYAKSFFKEQ
                     HIDIQFEPGDSELLAQHTVDFLSFSYYMSVTQSHHPDHYQRGEGNILGGLVNPHLPSS
                     EWGWQIDPIGLRITLNDYYDRYQIPLFIVENGLGAKDKLVQTKDGHWTVQDDYRIDYM
                     RQHLLQVAKAIEDGVDIMGYTSWGCIDCVSMSTAQLSKRYGFIYVDRHDDGSGHLTRY
                     KKKSFAWYQRVIETNGRSLSEES"
     gene            complement(18652..19467)
                     /locus_tag="TVB59_000920"
     CDS             complement(18652..19467)
                     /locus_tag="TVB59_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEL1009827.1"
                     /translation="MIRFLILAGYFELTMYLELSGKLNQYINIRYAYLAYISMVLSFI
                     LALVQLYTWTKNIKLHSHLKGKVAQLTSPLILVFPVLVGLLVPTVSLDSTTVAAKGYT
                     FPLAAGASKTGVSDDGTTIQYLKPDTSLYFTKSAYQKEMLNELKKYQGKSAITITTDN
                     YMEVMELIYLYPDEFVDRTIQYTGFVYNEPGHDSYQFLFRFGIIHCIADSGVYGLLTT
                     GNQESYANNTWLTVKGQLHMEYDKTLEQQLPVLQIEEAHQAPEPDNPYVYRVF"
     gene            complement(19467..20369)
                     /locus_tag="TVB59_000921"
     CDS             complement(19467..20369)
                     /locus_tag="TVB59_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEL1009828.1"
                     /translation="MSLFSNLPPSVLQWFAIFLSIIIEALPFVFLGTILSGCIEVFVT
                     PDLVQRYLPQNKWLRILFGTFIGFVFPSCECGIIPIINRFLEKKVPSYTAVPFLATAP
                     IINPIVLFATYSAFGNSLRFLMLRLLGAILVAVSLGIMLAFIVDENILKESTQPVHCH
                     TYSHESLPKRLYLALAHAIDEFFDTGRYLVFGTLIASAMQIYLPTKVLTAIGHSPLTA
                     ILVMMLLAFILSLCSEADAFIGASLLSTFGVAPVLAFLLIGPMVDIKNLMMMLNSFKG
                     AFIVQFISVSAVMITIYCLLVGVL"
     gene            complement(20410..20565)
                     /locus_tag="TVB59_000922"
     CDS             complement(20410..20565)
                     /locus_tag="TVB59_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009829.1"
                     /translation="MAITHKKNDQLEKMMAGFASIPDFDKPLELNQDGKLVTEKPKPQ
                     VKTAKQD"
     gene            20737..21459
                     /locus_tag="TVB59_000923"
     CDS             20737..21459
                     /locus_tag="TVB59_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003104099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1009830.1"
                     /translation="MTKRVLLVDDEEPILRLLDYHLAKEGFVTEMVTDGRTALALAER
                     EPYDFIVLDIMLPQLDGIEVCKRLRAKGSKTPIMMVSAKSDEFDKVLALELGADDYVT
                     KPFSPRELLARVKAILRRTEAEISGDGEERREPFYTMSQLRLYPERHEVYKDKELLPL
                     TPKEYELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKAP
                     QYIQTIRGYGYKFKELKNDRTS"
     gene            21443..22768
                     /locus_tag="TVB59_000924"
     CDS             21443..22768
                     /locus_tag="TVB59_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEL1009831.1"
                     /translation="MIGHLRRLSMLLGLCLLAALGLIWQGPHQVLTLVVLCTGLVASF
                     YVLSMLFRWEREFRALHHHLLTASDHFLLVGQADLSAYAKQLTELKSDLLQKEARLKA
                     LSKNVEAVTSHLTMGMLLVSNQRELLLTSKSLPAYFPEAKPPFVVLEDLKRMDLIALV
                     NQVFDQKQTLKKELTGLHDGDLILEVTLVPIFNQSHVVKEILVLLYDLTAIRHYERLN
                     LEFIANASHELRTPVTSIKGFAETIKEMPDDETSLKEDFLDIIYNESLRLERIVEHLL
                     TLSKANKTPLDLTEFQLRNFLLYTGQSMRPQLEQKQLELSYALEDSIVVTSDQYLLSQ
                     IMLNLLSNAIQYTDNGGRIQLSSQRVAGGVAITVADTGIGISQIELDRIFERFYRVNK
                     GRSRQSGGTGLGLAIVKELSQLLGGQITVTSQLGEGSQFTLFLPEAINK"
     gene            22927..23799
                     /locus_tag="TVB59_000925"
     CDS             22927..23799
                     /locus_tag="TVB59_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HEL1009832.1"
                     /translation="MTIKKMLIMAAIGLSGLGLAACGNNSADAGKAADRIDLVSRENG
                     SGTRGAFTEMTGILKKDGDKEIDQTAKTAIIQNSTEGVISSVKGNSRAIGYISLGSLN
                     SDVAALKVNGVKASRETILEGKYPLQRPFNIVWSSDLSGVGKDFITFIDSKQGQEIVR
                     DNRLIEAKTDAPAYSSKGLSGKLSIVGSTSVSPLMEKLAEAYKKENPAISIDITSNGS
                     SAGITAVKEKTADIGMVSRDLTTEESKGLIDDAIALDGIVVIVHKDNKVSNIGIDVLA
                     DVFSGKLTSWDKVK"
     gene            23869..24732
                     /gene="pstC"
                     /locus_tag="TVB59_000926"
     CDS             23869..24732
                     /gene="pstC"
                     /locus_tag="TVB59_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEL1009833.1"
                     /translation="MNKQAFKEDFFKVIFFLSAAMAIIAICLICIFIFSNGLPFIAKY
                     GMRAFLLGNDWSPSNQPASYGILPMIAGSFVITLGAMVIGVPTGILTSVFMVYYCPKA
                     CYGFLKSAVNLMAAIPSIVYGFFGLQVLVPWIRSFAGNGMSVLTASLLLGIMILPTLI
                     SLSESAIRAVPKAYYSASLALGASHERSIFRVILPAAKSGLFSALILGFGRAIGETMA
                     VILVAGNQPVLPSGLFEGTRTMTTNIVLEMAYASGQHREALIATSAVLFGFILIINAC
                     FAYVKGKSAHD"
     gene            24725..25540
                     /gene="pstA"
                     /locus_tag="TVB59_000927"
     CDS             24725..25540
                     /gene="pstA"
                     /locus_tag="TVB59_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEL1009834.1"
                     /translation="MTNYLLKALVYLLSLLTFGSLFLIIAFMLIKGLPSLSLSLFSWT
                     YTSDNVSLMPSIISTVSLVLGTLVLALPIGVFAGFYLVEYAKQDSLWVRAIRLAADTL
                     SGIPSIVFGLFGMLFFVVFFGLQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDHLRQ
                     ASLGLGAGKLRTIFKIVLPAAMPGILAGVILAIGRVVGETAALMYTLGTSTNTPTSLM
                     SSGRSLALHMYMLSSEGLHVKEAYATGVILLITVLLINALSSLLSRRLVKGVV"
     gene            25542..26294
                     /gene="pstB"
                     /locus_tag="TVB59_000928"
     CDS             25542..26294
                     /gene="pstB"
                     /locus_tag="TVB59_000928"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEL1009835.1"
                     /translation="MGAFSTKQLNVFYGAFQALKDISIDIPENQITALIGPSGCGKST
                     FLKTLNRMNDLIPSCRIEGEVLLDNQDIYAKAINLNSLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGLKDKKTLDQLVEQSLRGAAIWDEVKDSLKKSAMSLSGGQQQRLCIARA
                     LAVAPDVLLMDEPTSALDPISTLKIEDLVQQLKQDYTIIIVTHNMQQASRMSDKTAFF
                     LTGDICEFGDTAELFTKPKDKRTEDYISGRFG"
     gene            26570..26896
                     /locus_tag="TVB59_000929"
     CDS             26570..26896
                     /locus_tag="TVB59_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009836.1"
                     /translation="MKKLLLTSAAALALATVAVSTTKVEAFSRGHVIEHTINDTKSLS
                     AARWGSRLQILNLLTRFKHKLGEDGFRSYNRQFRARVGAAKSVSEIDELYNKFEKELE
                     ELEDLT"
     gene            27064..29196
                     /locus_tag="TVB59_000930"
     CDS             27064..29196
                     /locus_tag="TVB59_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEL1009837.1"
                     /translation="MENMNHQNISEALGVTPKQISQVLTLTAEGNTIPFIARYRKEAT
                     GNLDEVVIKAIIDMDKSLTQLRERKDTILAKIEGQGKLTAALKEAIEAADKLADLEEL
                     YLPYKEKRRTKATIAREAGLSGLARLILQNAQDLETKAEAFITEGFSDPQAALAGAVD
                     ILVEAMSEDSRLRSWTYNEIWKYSRITSSLKEASLDDKQVFQIYYAFSETVSNMQGYR
                     TLALNRGEKLGVLKVSFEHHIDKMLRFFSLRFKEHNAYIDDVINQTIKKKIVPAMERR
                     IRTELTEMAEDGAIKLFSENLRHLLLISPLKGKMVLGFDPAFRTGAKLAVIDPTGKLL
                     TTQVIYPVAPANQAKIQAARVALAQLITDYQIDIIAIGNGTASRESEAFVAEVLKDFP
                     ETSYVIVNESGASVYSASELARHEFPELTVEKRSAISIARRLQDPLAELVKIDPKAIG
                     VGQYQHDVSQKKLSEHLDFVVDTVVNQVGVNINTASPALLAHVSGLNKTISENIVRYR
                     EENGEITSRAEIKKVPRLGAKAFEQAAGFLRIPNAKNILDNTGVHPEAYPAVKKLFQL
                     LAIKDLDEPARAKLQAVNLEEMAEQLTLGQETLKDIIADLLKPGRDLRDDFEAPVLRK
                     DILSVKDLAVGQRLEGTVRNVVDFGAFVDIGVHEDGLIHISEMSEAFVNHPSQVVSVG
                     DLVTVWVSKVDLDRHKVNLSLVPPRESD"
     gene            29183..29620
                     /locus_tag="TVB59_000931"
     CDS             29183..29620
                     /locus_tag="TVB59_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003097487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEL1009838.1"
                     /translation="MSLTDYVREVSLADFGKPFKHQASWNRRLRTTGGRFFPKDGHLD
                     FNPKILEEHGETVFRQIVRHELCHYHLYFEGLGFRHKDQAFKELLDQVDGLRYAPKLQ
                     SHQANYLYICQDCGQAYDRKRPINLAVFACGRCHGRLIEKNQS"
     gene            29684..29956
                     /locus_tag="TVB59_000932"
     CDS             29684..29956
                     /locus_tag="TVB59_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEL1009839.1"
                     /translation="MESKFYKQRKHKLVAGVISGLADKYGWDLPLARVLAALLIYFTR
                     FGVVIYILLAIFLPYKEDLLEERYGRGPRRRKDADVLNDEDEGWFW"
     gene            30234..31166
                     /locus_tag="TVB59_000933"
     CDS             30234..31166
                     /locus_tag="TVB59_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEL1009840.1"
                     /translation="MTVTVKMLVTKVKLDVVYATDDLLEKEITTSDISRPGLEMTGYF
                     DYYAPERLQLFGMKEWSYLTQMTSHNRYSVLKEMFKKDTPAVIVSRGLAIPEEMVQAA
                     QEEGIALFSSRVSTSRLAGEMSYFLDASLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDVFAKDEETLWGEPAEILRHLLEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAIYLENFEAGKVFDRLGNGNEEITFSGVSIPRIRIPVKTGRNVSVVIE
                     AAAMNHRAKEMGFDATKTFEERLTRLISKNEEGK"
     gene            31163..31942
                     /locus_tag="TVB59_000934"
     CDS             31163..31942
                     /locus_tag="TVB59_000934"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEL1009841.1"
                     /translation="MINPIAFKLGPLSLHWYAVCILVGLLLAVYLAAKEAPRKKMTSD
                     DIIDFILIAFPLAIIGARIYYVAFEWSYYSQHLSDIFAIWNGGIAIYGGLITGTIVLF
                     VYCYYKVLNPIHFLDIAAPSVMLAQAIGRWGNFFNQEAYGRAVSQLNYLPSFIRQQMF
                     IDGSYRVPTFLYESMWNLIGFVIIMVWRRKPRSLVDGDIISFYLIWYGCGRLVIEGMR
                     TDSLMLLGIRVSQYMSVLLIIIAIVFIFKRHRQKGISYYQE"
     gene            31964..32368
                     /locus_tag="TVB59_000935"
     CDS             31964..32368
                     /locus_tag="TVB59_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007892823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEL1009842.1"
                     /translation="MNLVGISLLIIALAFVALVIFLIVVLKKVSEAVDEAKKTITVLT
                     SDVNVTLYQTNEILAKANVLVDDVNGKMTTIDPLFVAIADLSESVSDLNVQARHLGRR
                     ATNATSNAAKVGKVALVGKVASKLFGKKEKRS"
     gene            32365..32790
                     /locus_tag="TVB59_000936"
     CDS             32365..32790
                     /locus_tag="TVB59_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEL1009843.1"
                     /translation="MSNFFKTLVIGVASGAATAYFLSTEKGKVLKARAQRAYEAYRQN
                     PEEYHQMAKEKGSEYSQLARHTFNDLKTRFESGDMTTDQVFDFIKEKTSQFVHQAKEA
                     ASEHDKADDVIIDLDEEDIIINYPEDDSEKEAASNKSEE"
     gene            complement(32916..33197)
                     /locus_tag="TVB59_000937"
     CDS             complement(32916..33197)
                     /locus_tag="TVB59_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEL1009844.1"
                     /translation="MPTPLEQRQLKQQKQEQVSQQKFQEFQDLNGHSSKLKELIFFAR
                     IAVFSLITVLFAFVLLVMNLAPVWAFLIASAISLAITSFLSKAITLLMS"
BASE COUNT         9855 a         6090 c         7789 g         9546 t
ORIGIN      
        1 tagcagcagt caatagctcg tgcctatttg gtacaatatt tctgaaaaat ccacttgtga
       61 taagcctttc aagtggattt ttgttataat agaatggttt ataaggacat tagaaaagga
      121 gatttgtcat gatgaaaaag cttgaggccc tgctggaaaa ctcttttaat atccgttttg
      181 atgataaaag attactagag actgccttta cacatacctc ttatgctaat gagcatcgcc
      241 tcctaaacat ttcacataat gagcgtttgg aatttttagg agacgccgtt ctacagttaa
      301 ttatttcaga atacctcttt gccaagtatc ctaagcagac tgagggtgat atgtcaaaac
      361 tcagatcaac gattgtcaga gaggaaagct tagcaggctt ttcacgctat tgttcgtttg
      421 atgcttatat taagcttggc aggggcgagg aaaaatcagg aggccgtcat cgtgatacga
      481 ttttaggcga tttgttcgag gcttttttgg gtgctcttct tttggataaa ggcattgaag
      541 aggttcgtcg ctttttaaat caggttatga ttccacaggt tgagcaggga acttttgaga
      601 aggtcaagga ttataaaacc tgcttgcagg agttgttaca ggctaagggt gatgttgtga
      661 ttgattatca ggtgattagc gagactggac cagctcatgc taagcaattt gaggtagctg
      721 tattggttgg tgaggatcat cttagcaagg ggacaggtag atctaaaaaa ctggcagagc
      781 aggacgctgc taaaaatgcc ctggcccaac ttagtgaggt ctaaatgttt ttaaaagaaa
      841 tacaaatgca gggctttaag tcttttgcag ataagaccaa gattatcttt gataaggggg
      901 tcacagctgt tgtagggcca aatggctctg gaaaaagtaa tgtgacagaa agccttcgtt
      961 gggcacttgg tgaggccagt gccaaaagcc tgcgcggtgg caagatgcca gatgtgatct
     1021 ttgctggaac tgagcatcgg agtcccttga attatgcaga ggtggctgtt gtcttggata
     1081 attcagatgc ctttattaag aatgctcaga aagagattcg tgtggagagg catatctatc
     1141 gcaatggcga cagtgattat ctgattgatg gcaaaaaagt taggctaaga gatattcacg
     1201 agctgtttat ggatacagga ctagggcgcg attcgttctc tattatttct caaggtcgtg
     1261 ttgaggagat tttcaatagt aagccagagg aaagacgggc catctttgaa gaggcagctg
     1321 gagttttgaa atacaagacc cgcaagaagg agacgcaaac taagctaaac caaactcaag
     1381 ataatcttga ccgcttagac gatattatct atgagcttga gcatcaagct ggtcctctag
     1441 aaagacaggc gaaaactgct aggcaatttt tagccttaga tgctgatcgt aagcagctgc
     1501 agctggatat tttggtcaag gatatagagc aagaccgcat ggagcaggag gctcaagaaa
     1561 aggccttagt agctcttcgt gaggatctag cggcctatca taggaagcgt cagagtctag
     1621 aggcggaaaa tcaccgtcta aaaaccaagc ggcaaaagct ctctgctgta gctgagcaga
     1681 cgcaggctga tttgctagaa ttgacaaagg tcatatcaga tctggagcga cagattgacc
     1741 tcatcaagct ggaccttagt caaaagcagg aaaagaaaac agaagccagt cagcgcaggc
     1801 agcaggctca ggagcaattg cttgcctttc aacaggagca tcagcaaaag agtcgtcagc
     1861 tagatgaaat ccatcaagcc ttagctgagt ttaataccaa ggtcagcgag ctttctcagg
     1921 agcttgagcg attttctagc gatccagatc agctgcttga ggctcttcgt gaggattttg
     1981 ttggtctgct ccagcaagag gctgatgtgt caaaccaatt aaccgctatt gtagcgcagc
     2041 tggataagga aagtcaggcg aaagccagtc aggcgcagga ataccaagtc ctacaagaga
     2101 aggtcaatca gctcagtcag gacacccaga ctgctctttt ggcttatcaa gctagtcaat
     2161 caagacttga gcagctccta gctgattatc aagagctagc aaagacagtt gaggccttgg
     2221 agcaggatta tcatcaggga cagacaaggc tttttgattt gttggatcag aaaaaagcca
     2281 aggaggctcg tagggctagt ttggtttcta tccaaaaaaa tcatagtcaa ttttacgcag
     2341 gtgttagggc agtgcttcag gctgctggta agctagatgg tattttagga gcagttagtg
     2401 agcatttgac ctttgatagt cagtatcaaa cggcacttga gattgctttg ggagctagta
     2461 gtcagcatat tatcgtggca gatgaggcag cagccaagcg agcgatagcc tttttaaagg
     2521 ctaatcgtca ggggcgtgcg acctttttac ctctgacaac gattaaggcc cgtcagcttt
     2581 ctgaggtgac tctcaagcag ctcagggctt gtcagggcta tttaggcaca gctgattctt
     2641 tggtgaccta tgagccctct ttggtcgcta ttgtacaaag cctgttaggt gtgacggcta
     2701 tttttgatac cattgatcat gctaatcagg cagctaagca gctgcattat aaggtcagga
     2761 ttgtaacgct tgatggtacc gagctgcgtc ccggtggtgc cttttcaggg gggactaatc
     2821 gtcacaatag cacaaccttt atcaagccag agctagagca gattgagaag gaattagcct
     2881 tgctttctga gcagatcaag gaatctgaaa aagcagtagc tgctgtacag gctgatttga
     2941 aggctaaaaa ggctgcgcag gctgatacta agctggctgg tgagcaagca agactggtcg
     3001 agcaaaaaac acaattggcc tatcagcagc tagcagaaaa gctggctgac tcaaaagagc
     3061 tgctagagct tctcagcaac cgtcagactg gtcagtctag tgagcgctta ttatcagaaa
     3121 aagcgaggct ggaggaggca ttgcagctcc tagctgatga aaaatcagcc ttaacgtcag
     3181 aaattgagca aattaaggaa aataaagata cgattaagca aaagaaggac cagcttagcc
     3241 aggaattatc tcaggctcgt cttaaagagc gagatttgct caacgagaaa aagtttgaag
     3301 cagctaacca gcgtcgcttg gagacgatga ttgctcaggg tcagaaggaa ttagctaatt
     3361 tggagactgt tttatcacat caggttagtc aggaggccat tgaccaattg cctcacctag
     3421 aaaatcagct gacagaggct aatcaagaca agatcaagac tcaggagcgc ttcattcagc
     3481 tgcgctttga aggtgaggac tatgacgcca gactggagga gctagaggct caattgctta
     3541 aggaagccaa gaaaaatgaa gcgttcattc gtcagcaggc aagactggag gctgacttag
     3601 agcaggttat tggtcgtttg cggcagcacg ctagaagcct atcagaggag cttcagctaa
     3661 gcttagagga ggccaaggag caggcaagcc caatcaatga cactgacatg gcagcagcaa
     3721 gacagaaatt gcagcaggtt cagcaaagca ttcgtgccct aggcccaatc aatagtgatg
     3781 ctattgctca atttgatgag gttagtgagc gtttggcctt cttaaatggt caaagggctg
     3841 accttatcaa ggccaagaat ctcttggtag atacgattgg caatatggac catgaggtta
     3901 aggcacgctt tagggttacc tttgaggcta ttcgtgatag ctttaaggag acctttaggc
     3961 agatgtttgg cgggggctca gcggacttga tgttgacaga gactgatctg ctttctgctg
     4021 gagtagatat ttcagtgcaa ccgcctggta aaaagcttca atctttgaat gtgatgtctg
     4081 gcggagaaaa agccttatca gcgctagccc ttttatttgc tattatccgc attaagacca
     4141 ttccctttgt gattttagat gaggttgagg cggcccttga tgaggccaat gtcaagcgtt
     4201 ttggagatta tctcaatcgt tttgacaagg atagtcagtt tatcgtggtt acccaccgca
     4261 aggggacaat ggcagcagca gacagtattt atgggattac catgcaagaa tctggtgttt
     4321 ctaaggtagt atctgttaag ctcaaggata cgcaggatct gacttacttg tcataactct
     4381 aggacagagc ttagttttag ctgtatttct acatgtagca gatgataacc aagaataagc
     4441 tataaaaaaa cctatcgtca tggtaggttt tttggctttc caaaggacaa agcacaagga
     4501 ttggctagca gtaagctgct gtttttgaca tgctcctgga acttagtacg gcttgttttg
     4561 attaaaatat accaaaaaag taactaagga cataatatat tgacaagtag atgtctgtat
     4621 attataattt aattacaaaa tgagaataat ataaataaga tttggcgttg atttcaccct
     4681 aattagtcat gctgccttcc ttagagtgac ggacgcatag caaaagagtg aaaggaggac
     4741 atgatgacag ttaagaccaa taagcaaagg ctatggctag gcttaataat agtaatagga
     4801 gcgatcataa tggtttttcg tttgaatggc aaaagaacag aggaacaaca aaaaagggac
     4861 ttggaaacca gtattgctaa gctgctggtt catgactatg aaggggttaa agaagttaag
     4921 tttacaggct ggggacattc tcgggaaaca ggttcgtggg gaacgatagt gattataaat
     4981 ggagaaaatg aaataggctt ttcgtttgat ggcttgtcta gtcttgagaa aatacgagga
     5041 attgttactg atgatgatac agaaaagatg gaaaagcctg aaactgatac caaaccaaga
     5101 attatggata ggattgacaa gattaataaa acatctcttg taggtgttac tgtcatttat
     5161 tcaaaggaca atcaggagga ttaatatggc gatatcggat agtagttata atgagttggc
     5221 taaacaggtt tataatgtcg aacctagcaa agctaaatca aatggagacc ttgttattgt
     5281 tgctggtaaa actgtaaaag atcctatcac taaacgacaa taccgagtcc tcttagttca
     5341 ggacaataac aacgatgccc ataaaaccaa tgacaacggt atgcaggcaa tggctgtagc
     5401 ccctattgtt aaaggtgata tcgatacctc tcaggttgtg attgcctatg cagggacaaa
     5461 tgctgcggat tccagagatc ttgatacgga ttggcagctg ctcattcggg gcaatcaaga
     5521 tgatttagtc agcggcaata ttgatggtgg caattttgtt attgccgaaa accaattacg
     5581 atctgctcaa aagttttatc aacaggtcaa aagaaagtac cctcattctg ccttaacaac
     5641 cacaggtcac tctctcggag cttatctagc actaatagtt gccgcagaac ataagatccc
     5701 agcaacaacc tttaatggtc cagaccctgt tcgcggcatg tcagctgaag ctatcacatg
     5761 ggttaaggct aatagcaata tgtacaataa tttccgcatt aattttgatg gcattggcaa
     5821 ttttggtgcc tattttggaa ctgatgattt agctatttct cggaatgtcg atgctatgct
     5881 cttatcagcc aaccccttgt attatcacga tttaggagct tatcgtttta atcaaaaggg
     5941 tcagattgta gatagagacg gtaagctcat tggaacacaa taccttgtga gtcgggccta
     6001 tttaactgtc cttgcctcaa aaaagagcat gtcaagctac aatcagctca aaaaacactg
     6061 gcagtctacc ggcaagggga tcagtagttc tgaggagctc tttttagatg cggcacaggg
     6121 aatgatccta ggctcgtcca tggctaaggc tgctcgagag ggggctgatg aagctctgga
     6181 tcataaaacg gttgcagacg caaagcttat ggaagtgtgg tcggcgattg acttcaactc
     6241 ttttcatgag ctgccctact atgaggtgca ggccttattt gcttcttatg gtatcacata
     6301 tgaccgcttt gtccaagact ttcaggacta tactcaatcc aaggtcagca agctgtcagc
     6361 cttggccaca gactttgaaa acttgaatag agatattcag acggttattg atagcaagct
     6421 tgaaacggat cgtcagttag caggagagtt tagagcatgg cagacagaat tgtagaggaa
     6481 gtggctattt atcgtaagct tcgggagatg gatgatgccg agcaggactt tctacgccag
     6541 aaaagagcct atcagaagcg tgaagacagc ttatctgaaa gaagacatgt cttaaatgat
     6601 ttgatcaact ctgagtacca gaagatgagt gtttttttga agcgtttaga cctatctgcc
     6661 aatgctgcat cagatttttt caatgaattg ggtcgcttaa aggatcaatc caacgcagag
     6721 tttcatctct ttttaaaatt ggggaaaatt ttgaacaaca agtcactcgg ataatttcta
     6781 taggatgact aacttttact tgcaatttag catcttgtaa ttcaaataat aatatgatat
     6841 tatgctaata aataataata tattatttag attgttcaaa tatttttaac aatctatcca
     6901 atgagaacta atatgaaaaa ttggtgacaa aacattagtt ttgcttgctg taagcacttt
     6961 aagttttgga tctgctgcta cagctagagt tgttagtgca gcaacagcgc atccagctcc
     7021 atatccaatt attgatgaat ggaattatgg tgtaagtgat aactatggtt attctaatga
     7081 ctatgttaag tctccaaata atattggttc aaaatcttca gtaactaatc tatggggaac
     7141 agttaaggat agagattctc aaaaatatgg atgggcaaac tcaagcgcaa caaaaagctg
     7201 gaatgatgtt cgattaaata cacattggaa ttactttaca ttttaaaaat ggtttatgaa
     7261 agctaaaggc ccaataatgc tatagggcct tttatgatat aggtaggtgc ttatgaaatt
     7321 aaaattatgc attgttggat tcttcttttg tttaattgct gccattggtc tggttagtat
     7381 taatgatact caaaaaccaa tacctttacc aattgatggt gccttctcca ttcaagggaa
     7441 aagcaatctt tctaatgaag aagtgtatca aacgattagt gacctatcaa aagagaaaaa
     7501 agttaccatt tacaaaccgg tagttcaaaa ttcggggcag ttgacttata tcaagtttga
     7561 taatactaat catgaacaat taaagtctgc accaatcaca gggatgtatt ataccctagg
     7621 gaaattagat tcaaatagtt taaaaccgct cacatctaca ggtcttcaag tcatatatct
     7681 ggcttaccct tggcagatag ggggaatgat acaatttact ggtccgttga gattattgct
     7741 aatgatttca atttacttaa ccttattagt tgttctattt gttgttagag cgagacagat
     7801 taaagaagga gtgataagac gttctttagg attacctgta cacgacctaa gaagagatta
     7861 tttcatgtca tttacttttg aactggttat ggccgcttta ttgatgattt cttatagttc
     7921 ttttttgggt agtggttttt tcacctacag ttccaagtta tttttttcta tgcttttaac
     7981 taatttgatc atatttcaaa tcattgacat catcaccttt gttctatttt ggctaactat
     8041 taaggttgaa aaacctattg aaattataaa aaataaggcc aaaaatagcc tcatttttat
     8101 cgtatggctt gcggttattt ctatcataat agttgtttca ggagtctttt tacgggaaac
     8161 aaaggctagt caatcaaaga taaacatgca gataaagcat ttaaaaccat ggagtgcagt
     8221 aaaagattgg aaaagaccag agtttttggg tattgaaaat gaatctgtta ctaatggaga
     8281 agaagcaaat gactcaggag ctaagtacgt agagattgct aaagccttaa aaaaactgga
     8341 ttttatatat atcaaatcat cttcagccta tgttccagaa tatatggcag cttctgatgt
     8401 tacagaagat ttttctaagc aattaaaaag tgatggaata acgcatccag aagttaataa
     8461 ggaactggtt tatattaatc aaacaggtgc taaggtacaa aataaagtta atggaacgaa
     8521 ctatcaatca ttagataata aaatagcaac catctatatt cctcataaat ttaaagagaa
     8581 taaggcatca atcgagaata cagttgtagc agaacaattt actggtacaa actatacaaa
     8641 agatgacctt acggtgcaag tcattcctga tgggcaagaa tttttctatt tcaatgaaaa
     8701 tggtagtagt gttcctgaaa ataaagataa tctacctttg gaaagtgtga cagatagtaa
     8761 ggataatata gtcgttgtgc tagatactga taaaatgata gaaaataacg attttatttt
     8821 ggcaagtaat ataatatata actcactttt tagttcggaa gcaattaaga aaatcaacga
     8881 tttgagtgct agtttgaatt tttcaatcaa tccagtcgag gtttaccaaa ctgtaaaact
     8941 taatattcaa tccttagagc atcaaatttt cctttcaaaa atactgcaaa taattatttg
     9001 tggaatcgta tttctactca tttatcagta tgctcaaatg tttgttgcct taaaacagaa
     9061 tgactatgtt aaaaaaatca ttttaggcct atcgaaaaca cgtatagcca tttcaagtct
     9121 caactatttt attgtgacta ttacaatggt tattctattg acatttatgt tgacaggaca
     9181 agtagagcta ttatatattg gcattgcttc tttaatggtt ttaatttttt caacaataat
     9241 gagttttaga aaattatctg aaaaatatac acaaattcta aaaggagatg actaatggca
     9301 attgaagttt tgaatgttac caaaaaattc ggctcaaaaa agatattcac agatttaaat
     9361 ttaacgtttg aagctggaaa aagctacgca ttgattggag gctctggttc aggtaaaagt
     9421 acactactta atatcatagg aagactagaa aaaattgaca gtggaaaggt tttagttgat
     9481 gagcaggata tttggaagac aaaagaaaga actttcttta aaactattat tgggtatgta
     9541 ttccagaatt attctttaat agaaaacaaa acagtatatg ataatttgag actcatcaat
     9601 aaagataaaa aaataatagc tgatgtactt gaaaaagtag gactttctaa tgactattta
     9661 aatcagaaaa tatatgaatt atctggagga caggttcagc gtgtagctat tgcaagaatg
     9721 ttaatgaagc cacgtaaaat tattttagcg gatgaaccta caggagcttt ggatagtgag
     9781 attggaaaag aaatcattaa tttattattg agtgaaacag ccgaaaataa atatgttatt
     9841 atagcaacac atgatccagc tgtatataat aaggttgatg ttatcattga tttgaaagat
     9901 atagggagtg agatatgaaa aagaaagctt atatgacgtt gatattatta attggaatac
     9961 tcgcaatttt cttagtggga aaacaagtaa taaaaaaaga aaatcccaat aaacctacgg
    10021 tagatttaac agtctatacg atctcttcta gtgataccca aaaatggaat aaagtaagac
    10081 aattagaaac agaagaagcc atatacctaa taagggtaaa agaagcagca tcttcagaag
    10141 aaatattttc aaacatcatt gcagacggag ctgctatggg ttttggagtt agtgaagaag
    10201 atgttaaaca attcaacaat catttagaga atactataga agattctaag aataacaaat
    10261 taatcgaaat ggaatttttt gatttttcta acaataacaa ggggtttgtg gtagcaaatt
    10321 ttgattacgg taaaaaagag tttaatgctc agaaaaaaga aaagaaagcg ttatataaaa
    10381 aactatatga agcttttaag gagaaaaatc atcagtctag atagattcat tactcaactc
    10441 tttagtaaca agaaaactta gtgacgggct tcaattaaga attatggcaa ataagcgttg
    10501 agagtatgga gataaagaag tttagccttt aaaaacggag ctcagattga ctgttaaaac
    10561 aagggtatgt cagatggcac gccctttttt ggtctacctg tggtataacg aaaggagtta
    10621 tactgggatt tgagttgcac accccactcg ggttttgcac tcccttgaaa gtgaaatggt
    10681 tagattgtat gttaaagtta attgcaacag aaattggaat aaggaaattg atacaataga
    10741 acataaagaa agccttggaa taagggctca ataatctcca cagtggagtt acccactaca
    10801 gaaattataa agccttaaaa caaggacgtg ttaggacagg cacgcccttt ttgtttagat
    10861 atggtataat ggaaaaagag atttttggga gagctgaata gctgaatcag tatctcccta
    10921 aaaaggaaat ggttaaattg tatggttaaa ttgatagcaa cagatatgga cggaaccttt
    10981 ttaagagagg acggaactta tgacaaggag cgcttggcag ctctgttgcc taagctaaga
    11041 gaaaaaggga ttctctttac agtttctagt gggcgttcgc ttttagccat tgatcacttg
    11101 tttgagcctt ttttagatga cattgccatt atcgctgaga atgggtctgt ggtgcaatac
    11161 aagagggaca ttctttttgc tgatgtcatg accaagcagc agtgtcatga cattgtagag
    11221 aaaattcttg ccaatcctta ttacaatcag tctgggatcc tcttttcagg gcaaaaggca
    11281 gcctatgtgc tcaaaggagc tacggaggat tatatccaaa aaatgcatta ttattatgaa
    11341 aatgttcagc ttattgattg tctgcaggat attgttgatg acactgtttt taaagcctca
    11401 acgaccttta caggagaaac agtcttagct ggcagtgact ggctaaatca ggagctgtcc
    11461 tatgcttctg cggtgacgac tggctttgat tcgattgata ttatcctaaa agaggttcat
    11521 aagggctttg gcatggatca gctgtgtcag cacctaggca ttttaccgga aaagaccatt
    11581 gcctttggcg ataatctaaa tgattatcaa atgctgtcct ttgcagggca ggctattgct
    11641 actgaaaatg caaggcctga aatcaaagcg atttctgatc aggttattgg tcattgtaat
    11701 gactcagcag tgttaactta tttggaggga ttggtgtaaa tgacgcgtat aaagctttta
    11761 gctctagatt tagatgggac tctctataat accgaaaaaa tcgttagtga tgagaacaaa
    11821 aaagctctag cagcagctaa ggaaaaagga gttaaggttg ttatcacaac cggacgtcct
    11881 cttaaggcta tcggaaattt gcttgaggag ctggatttgc taggtgaaga gaactatagc
    11941 attaccttta atggcggtct ggttcaacga aatactggtc atattttaga taaaagcgct
    12001 ctaagccttg ctgaggttta tgacattcat cagcagttgg cagcggttgg cttacctact
    12061 gatgttatca gtgatggtac tgtttatagt ctatcaggca atgatggcag acgctctcag
    12121 tatcacttgg caagtccctt gctgaacttt gttagcctta aatcatttgc tgagctgcca
    12181 aaggacatca catacaataa aattgttacg gtgacggatc caaaggtctt ggatcagcag
    12241 cttgcaaggc ttccaaagac tatctttgag gattttgagg cctttaaatc acgagacatc
    12301 atctttgaga ttatgcctaa ggggattcat aaggcatttg gtttggacct gctttgtcag
    12361 cacttgggct tggaggccaa gcatgtcatg gcgatgggag atgaggccaa tgactttagc
    12421 atgctacaat gggcaggtct tggtgtggct atggccaatg cggttgatca ggctaaggaa
    12481 gtggcagatg cagtgactac cctaaccaat gaccaatcag gtgtggctga ggctatttgg
    12541 aaatatattt taaatgagga aggctaatgg gattatttga acgcttattt ggaaaaaagg
    12601 ataagactaa ggttgctgag caagaggctg ccactacaga ggtattgtcg gaggacataa
    12661 cgtcaaagga tacgattgag tctgaaaagg aggccttatc agatacaaat gctcatgcag
    12721 tggcagctga tgtggtctct aggaccgatg acactagcaa acaggctgag ctctcagacg
    12781 aggctgcttc agagcaagct gaagggcttg atccagcagc tagaggagct tttcttttag
    12841 aaagagagcc ggagctagag ttagcagcta ctgatgacaa gaccttggat caggcaggtg
    12901 agagcctaag ccagcacgag gctatggagg aggctaagca tgatagggct aagtcagagc
    12961 atagtaacga gagcgcagac gcatcaacag aagatcaggc agagacaaat gctgagtatc
    13021 aagtagcagc tcaagcacct gctggttcag ctgatcagcc agctgaggaa ggccaaaagc
    13081 aagagaccct atcagctgaa tctgatcagg aaaaatacaa gcgcagctta aagaaaaccc
    13141 gtacaggctt ttcagcacgc ttgaacagct tctttgctaa ctttagacgt gttgacgagg
    13201 acttctttga ggacttagag gagcttttga ttctctcaga tgttggtgtt catgttgcca
    13261 caaccttgac tgaagaattg cgctatgagg ctaagcttga aaatgctaaa aagccagagg
    13321 ctctaaagcg tcttatcatt gataagctag tggctattta tgagggggat ggccgctaca
    13381 atgaagcgat tcattatcag cctggcttga ccgttatgct ctttgttggg gtgaatggcg
    13441 ttggtaagac aacatcaatt ggaaagctag cttatcggta taagcaagag ggaaaaaagg
    13501 ttatgcttgt tgcagctgat accttccgag caggcgcggt tgcccagctg gttgaatggg
    13561 gacgacgggt tgatgtgccg gtcattacag gccctgaaaa agcagatccg gcctctgtgg
    13621 tctttgatgg cgttgagagg gctgttgctg aaagggcaga tattctcctg attgataccg
    13681 caggccgcct gcaaaataag gacaacctaa tggcagagct tgaaaaaata ggacgaatca
    13741 ttaagcgtgt catacctgat gccccacacg aaaccctgct agcgctcgat gcctcaacgg
    13801 ggcaaaatgc tctgagtcag gctaaggagt tttcaaaaat cacaccgctc acaggcttga
    13861 ttttaactaa gattgacggt acagctaagg ggggaattgt cctagctatt cgtcaggaat
    13921 tggatatccc agtgaagctg attggctttg gtgaggctat tgatgatatc ggtgaatttc
    13981 actctgagga ctttatgaag ggactattag aaggcatact ttaagaggaa agcctcagat
    14041 tatcggctgt tggccaaaga gaatgagggg gttcgtttag aggcaaatgt caaacagcct
    14101 tttgaaaacg cttgacagga cctttaggag atgataaaat gaaaacgtta ttagatgtga
    14161 ttacttaggg taagcgtgct aatgacaaat gaatcagaat attaaaggat gttatcacag
    14221 ttttgtgagc agggacctat tccagtgtgg ccttttagca tgctgtggat aggtcatttt
    14281 ttattgtgaa gcaatgaggg actaggactt ttatgattat taaacgcgtt ttaaaccata
    14341 atgcagcgat ttcgaccaac catcaggggc tagatattct tttgatggga aaggggattg
    14401 cttttaagaa aagaattggt gaccatatcg atagtgaagc tatcgaagcg tcatttgttt
    14461 taaaaaatag tgacaatatg aaccgtttta ctgaattatt tattgctgtt ccgcaagagg
    14521 tggttgcttg ctcagagagg cttattaatc tagggaaaat taagctgggt aaaaatttag
    14581 atgaaatact ctatatcaat ttgacagacc atattcattc agctattgaa agacataagc
    14641 aggggatgat cattagtgat cccttgcgct gggagattag acggtattat cctgatgaat
    14701 atgcgattgg cgttaaggcc ttagaggtca ttgccagtga gctaggagtc gctctggctg
    14761 tagatgaagc ttcgtttatt gcgatgcact ttgtcaacgc gagccttgat aatcctttca
    14821 aggagcctca tcgaatgaca gaaattgtgt cttacattga acagaaggtc aaggctgatt
    14881 ttaagacaga gcttgatgaa gtctctattg attattatcg ctttatcact catgtgaagc
    14941 tatttgctca gcgcgtgtta tcaggcatgg cttatgatga tgacgagact gatttgctgc
    15001 tgatggttaa ggataaatac ccagaggaat atcactgtgt taggcaaatt agccatcaca
    15061 tgaaaaaagc ataccattat cagcttagct ctagtgagct tttgtattta acggttcata
    15121 tcaaacgttt agtcaaaaat gtgaaggagt aatgaaatga cttatcaaga aacagccaag
    15181 gccatttttg aagcagttgg tggtgagcag aatattcaag aggtaaccca ctgcatcacg
    15241 cggttacgct tggttttgaa agatgataaa caagtggtag atcaaaaaat caaacttatt
    15301 cctaatgtga ttggagtcat gcgccaaaac ggtcagtatc aaattatttt aggaaacgat
    15361 gttaacaatt attataaggc atttatgacc ctaggacagt ttcatgaaac tgatatgagc
    15421 tctagcgctg gtcaaaagca gtctatgatt gaagggttga ttgaaacgat agctagtgtg
    15481 attactccac tgatacctgc cttactggga ggcggtatgt taaaggtggt tgggatcttg
    15541 gtgcctatgc ttggtctagc aggtacggac tctcaaacag ttgcttttat taattttttt
    15601 ggagatgctg cttattattt tatgccaatc atgattgcat attcagctgc ggcacgcttt
    15661 aaggtcacac ctgtattagc agcaactgtt gcagggattt tactacaccc agcttttgtt
    15721 acgatggtag ctacaggtaa acctatggct ttgtttggag cgccggtgac acctgctagc
    15781 tatggtgcgt cagttattcc gattttaatt atggtttacc tgatgcaata cattgagcga
    15841 gaggttaacc gttttgtacc gagtgtgatg aagagcttcc tgcagccgac cttgattatt
    15901 tttatttcag gctttctagc cttagttgtt attggacctc tgggtgttat tataggacag
    15961 ggcttgtcta atagcctgct agcgatttac catattgctc cttggctggc tcttgctatt
    16021 ttaggtgcaa ttatgccgct tgttgttatg acgggtatgc attgggcctt tgctcctatt
    16081 tttctggcgg cctctgtagc aactccagat gttttaatcc tcccagcaat gctagcctct
    16141 aacctagctc agggatcagc agcggtggct gtagcatgtc aatcaaagca aaagcaaacc
    16201 cgtcaggttg ccttagcagc aggcttatca gctttattgg caggaattac agagcctgct
    16261 ctttatggca ttactctaaa gtttaaaaag ccgctctatg ctgcaatgat ttctggtggc
    16321 cttgtgggcg cctatattgg ctttgttaat atagcctctt atacttttgt ggtgccatca
    16381 ctaattggat tgccacaata cattagcccg actagctctg ctaattttac caatgcctta
    16441 attgcagcgg gcttaacaat tgctctaacc tttacattaa cctggttttt tggcattgat
    16501 gaggaggttg accaggaggg gtcagctgac tcggatagca cgccagtaaa aagtggctta
    16561 tcagcaaagc aatctattta tgctccgatg gttggcacag tgcttccatt atcagaggtg
    16621 ccagatgaaa ccttttcgtc taagctttta ggagaggggc tggctatttt acctaatgag
    16681 gaatatgtct atgccccatt tgatggcgag gttatcaccc tttttccaac aaagcatgct
    16741 attgctttaa agaacgccaa gggagttgac gtcttaattc atgttggtat tgatacggtt
    16801 gagctaaaag gacagggctt tgagcagctg gttaaggctg gtgatactgt taagcagggg
    16861 cagccgctgc tacgtataga tcttgaattg attggctcta agggctattc tttagtgact
    16921 ccatttgtgg tgaccaatag ctctgagcag ctcgaaatca ttgttaatga caacaaggag
    16981 catatcactc agcatgatgt tgctctcgtt attctctaaa gagatgaatt gaaggaggag
    17041 ataatatggt ttgttttcca aaggatttct tgtggggagg ggcagttgct gccaatcagg
    17101 ttgagggagc ttatttaaca gatggcaaag gcttgtcggt tcaggatgtt ttaccagaag
    17161 ggggcttagg agactataca gctgagccaa cagcagctaa tttgaagcta gaggccatcg
    17221 atttttatca ccgctacaag gaggacgtgg cgctctttgc agaaatgggc tttaaggttt
    17281 tccggacatc aattgcttgg tctcgtattt ttcctcaggg cgatgagaca gagcctaacg
    17341 aagcagggct acaattttat gacgatttgt ttgatgagct gatagcacat ggcatagagc
    17401 ctttagtgac cctatctcac tacgaaaccc cactgcatct agctaaggtc tataatggct
    17461 ggactgaccg tcgtatggtt ggcttctttg aacgttttgc gacaactgtc atgcagcgct
    17521 acaagaacaa ggttaagtat tggttaacct tcaatgaggt taattcaatc ctgcatatgc
    17581 cttttaccag tggtgctatc atgacaccaa aggaaaagct gactccgcag gagctttatc
    17641 aagcgattca ccatgaatta gtagcgtctg ctagtgtgac aaggcttgct agattgatta
    17701 accctgcttt taaaataggc tgtatgattt tggctatgcc agcctatcca atgacctctg
    17761 atccgaggga tattttagct gcgaagcagt ttgagcaacg taatctcctg ttctcagata
    17821 ttcaggtcag aggaaaatac ccttcctatg ccaaatcctt ttttaaggag cagcacattg
    17881 acattcaatt tgaaccgggc gacagtgagc ttttggcgca gcatacggtt gactttttat
    17941 cctttagcta ttacatgagt gtgactcagt ctcatcaccc ggatcattat caacgagggg
    18001 agggcaatat tttaggtggc ttggttaatc ctcatctgcc ctcttcggaa tggggctggc
    18061 aaattgatcc aattggcctt cgcataacct tgaatgatta ctatgatagg taccaaattc
    18121 ctctctttat tgtagaaaat gggcttggcg ccaaagataa gctagtacag acaaaggatg
    18181 gtcactggac agttcaggac gattatcgga ttgattacat gaggcagcat ttattgcagg
    18241 ttgctaaggc tattgaggac ggtgttgaca ttatgggcta tacctcctgg ggctgtattg
    18301 attgtgtttc tatgtcgact gctcagctaa gtaagcgtta tggctttatt tatgtcgacc
    18361 gacatgatga tggcagtggt catttgacac gctacaagaa aaaatccttt gcttggtatc
    18421 aaagggtcat tgagaccaat gggcgtagcc tgtctgagga gagctagaaa gtagcctcaa
    18481 aggctttacc aacaatagca aagccgtata gcacacgtct tttaaaaggc tgatgctata
    18541 cggcttttag ccatttcatt taaatggaac gaactcaatt acgtctttgt actgtcccct
    18601 aacaaaaagc ctccatagac ctgtgtcata ggtgtggagg cttaatgctt gttaaaatac
    18661 cctatagaca taagggttat caggctctgg ggcttggtgt gcttcctcga tttgaaggac
    18721 aggaagctgc tgctctaggg tcttgtcata ttccatgtgc agctggccct tgacggtcag
    18781 ccaagtgtta ttggcatagc tttcttgatt accagtggtc agaagcccat acacaccgga
    18841 atcagcgata caatggataa tcccaaatct aaagaggaat tgatagctgt catgtcctgg
    18901 ctcattatag acaaagccag tgtactgaat cgtacgatca acgaattcgt ctgggtaaag
    18961 gtagattaat tccattacct ccatataatt gtcagtggta atggtgatgg ctgatttgcc
    19021 ttggtatttt ttcagttcat tgagcatttc cttttgatag gcggatttgg taaagtacag
    19081 gctggtgtct ggctttaggt attgaatagt agtaccatca tcactgaccc ctgtttttga
    19141 agcgcctgcg gctaatggaa aggtatagcc cttggcggca acggtcgtcg aatccaagct
    19201 gactgtaggt actaacaagc caaccaaaac aggaaagacc aggataaggg gactggtcag
    19261 ctgagcgacc ttacctttta aatgactgtg tagcttgatg tttttagtcc aagtgtatag
    19321 ctgcaccaat gcaaggataa aggatagaac catagaaata taggctaagt aagcgtaacg
    19381 aatattgata tattgattta gcttgccaga tagctctaga tacatggtca actcaaaata
    19441 gcctgctaaa attaaaaagc gaatcatcac agcaccccca caagtaagca atatatggta
    19501 atcatcacag ctgatacact gataaattga acaataaagg ctcccttaaa ggaattgagc
    19561 atcatcatga ggtttttgat gtcaaccata gggccgatta agagaaaggc taaaacagga
    19621 gcaactccaa aggttgacaa taacgaagct ccaataaagg cgtcagcctc actgcaaaga
    19681 gataagataa aggctaagag catcatgact aagatggctg tcaaagggct atgtccgatc
    19741 gctgtcagca cctttgttgg cagataaatc tgcatggctg aagcaatcag ggtcccaaag
    19801 actagatacc ttcctgtatc aaaaaattcg tcaatagcgt gagccagtgc caagtaaagc
    19861 cgttttggca ggctttcgtg actgtaagta tgacaatgca ccggctgggt tgattccttg
    19921 agaatgttct catcaacaat gaaggctagc atgatgccaa ggctgacagc cactaaaatg
    19981 gcgcctaaaa gccttagcat gagaaagcgc agcgaattcc caaaggcaga gtaggtagca
    20041 aataaaacaa tcggattaat aattggagcg gttgctaaaa agggaacagc agtgtagcta
    20101 ggcaccttct tttctaaaaa acgattaata ataggaatga taccacattc acaggaagga
    20161 aaaacaaagc caataaaggt accaaataaa attcttagcc acttattttg agggaggtat
    20221 ctttgaacta aatcaggcgt gacgaaaacc tcaatacagc cagataaaat agtccctaaa
    20281 aatacaaaag gcagggcttc aatgataatg gatagaaaaa tcgcaaacca ttgaagcacg
    20341 ctgggtggca gatttgaaaa aagcgacatt caccgtatcc tttctatatg ttaacgacgc
    20401 caataagggc tagtcctgct tagctgtctt gacttgtggc tttggttttt cagtgactag
    20461 ctttccatct tggttaagct ctaaaggctt atcaaaatct gggatagacg caaagcctgc
    20521 catcatcttt tcgagctggt catttttctt atgagtaatt gccataggta taccttcttt
    20581 caatcaatat agctctatta tacaatcatt tgacggtaaa gccaaagcta aaacatcttt
    20641 ttatcttctg attgatttta ggcttcaggc cgtcaagcag tgtgtcatta gattgactga
    20701 caaatatgat ataatgtggc tgatgggagc tatgaaatga caaaacgagt attattagta
    20761 gatgatgagg agcctatctt aaggctactg gattatcact tggccaagga gggctttgtg
    20821 acagagatgg taacagatgg ccgtactgcc ttggcattag ctgaaagaga accttatgat
    20881 tttattgtgt tagatattat gctgccgcaa ttagacggta tcgaggtctg caaaaggctt
    20941 cgtgctaagg gaagcaaaac cccaattatg atggtttctg ctaaaagtga tgaatttgac
    21001 aaggttttgg ctttggagct gggggcagat gattatgtga ccaagccctt tagtcctaga
    21061 gaattattag cgcgtgtcaa ggctatttta aggcgtactg aagcagagat ttctggtgat
    21121 ggtgaagagc gtcgtgagcc tttttatacg atgagtcaat tgcgtctgta cccagagcga
    21181 catgaggtct ataaggacaa ggagctattg ccgttaaccc caaaggaata tgagctactg
    21241 ctctatctca tgaagcaccc taatatgacc ctgacgcgtg agcggctatt agagcgtatc
    21301 tggggttatg actttggcca agaaacacgt ctggtagacg ttcatattgg caagctcaga
    21361 gaaaaaatcg aggacaatcc taaggcgcct cagtatattc aaaccattcg cggctatggc
    21421 tacaaattta aggagctaaa gaatgatagg acatcttagg cgtttgagca tgctgctagg
    21481 gctttgcttg ctggctgctc ttggtctgat ttggcaaggg ccgcatcagg tgctgactct
    21541 agtagtgctg tgtactggtc tcgtagctag cttttatgtc ttgagcatgc tatttagatg
    21601 ggagcgtgaa ttcagagcct tgcaccacca tcttttgaca gctagtgacc attttctcct
    21661 agtggggcag gctgatttaa gtgcttatgc taagcagctg acagagctaa aaagtgacct
    21721 attacaaaag gaagcaaggc taaaagcctt atcaaaaaat gtggaggctg taacctctca
    21781 tctcacgatg ggcatgcttt tagtctccaa tcaaagggag ctgttgctga ccagcaaatc
    21841 cttaccggct tattttccag aggctaagcc accttttgtg gtcttggagg atcttaaacg
    21901 aatggatctg atagccttag ttaatcaagt ctttgaccaa aagcagacat taaagaagga
    21961 attaacaggc ctacatgatg gtgatttgat cttggaggtt acccttgtgc ctatctttaa
    22021 ccagtcgcat gttgtcaagg agattttagt gctcttatat gatctgacgg ccattcgtca
    22081 ttatgagagg ctaaatttgg agtttattgc taatgcttct cacgaattaa gaacaccggt
    22141 tacatcgatc aagggctttg ctgaaacgat taaggaaatg cctgacgatg aaacaagcct
    22201 aaaagaagac tttttagaca ttatctacaa tgaaagcttg cgtctagaac gtattgttga
    22261 gcacctgctg accttatcca aggctaacaa gacaccactt gacctgacag agtttcagct
    22321 caggaacttc ctgctgtata caggtcagag catgaggcca cagctagagc aaaagcagct
    22381 tgagctaagc tatgcattgg aggattcgat tgttgtgaca tctgatcaat acctcttatc
    22441 gcagatcatg ttaaatctct tatcaaatgc gatacagtat acagacaatg ggggcagaat
    22501 tcagctatcc agtcaaaggg ttgctggtgg tgttgccatt acagttgcag atactgggat
    22561 tggcattagc caaattgagc tagatcgtat ttttgagcgc ttttatcgtg ttaacaaggg
    22621 acgtagcagg caaagtggtg gaacaggcct aggcctagcc attgtaaagg agctgagtca
    22681 gcttcttggc ggtcagataa cagtcacaag tcagctagga gagggcagcc aatttacctt
    22741 attcttacca gaagctatca acaagtaaac agtcactacc agctacttaa ggccagcctt
    22801 ggtagtggct gttttaggtt ttacaaaatc tttacattaa tcagggataa acctttacaa
    22861 agacctgata agctataggt gtagcaagcc tacaacacaa tatcataaaa gataagggtg
    22921 attcttatga caatcaaaaa aatgctgatc atggcagcta ttggcttatc aggcttaggt
    22981 cttgcagcct gtggcaataa cagtgctgat gctggaaaag cagcagacag gattgacctt
    23041 gtttctcgag aaaatggctc aggtactcgt ggagccttta ccgaaatgac aggcattcta
    23101 aaaaaggacg gtgacaaaga gattgaccaa acagcaaaaa cagctattat ccaaaatagc
    23161 acagaagggg tcatctcctc tgttaaggga aatagtcgtg ccattggcta catctcgcta
    23221 gggtccttaa atagcgacgt tgcagcccta aaggtaaatg gcgtaaaggc tagtcgtgag
    23281 actattttag aggggaaata ccctctgcag cgtcccttta atattgtatg gtcctcagac
    23341 ctatcaggag ttggtaagga ttttatcacc tttattgact caaagcaggg gcaggagatt
    23401 gttagagaca atcgattgat cgaagcaaaa acagacgcgc cagcctatag cagtaagggc
    23461 ttatcaggca agctgtcaat tgtaggctca acctcagttt cacccttgat ggaaaaatta
    23521 gcagaagcat acaagaaaga aaatccagcc attagcattg atattacctc aaatggctca
    23581 tcagcaggta tcaccgccgt caaggaaaaa acagcagaca tcggtatggt ttctcgtgac
    23641 ctaacaactg aggagagcaa gggcttaatt gatgatgcga ttgcccttga tggtatcgta
    23701 gtgattgttc acaaggacaa taaggtaagt aatattggca tagatgtgct ggctgatgtc
    23761 tttagcggca agctaacaag ctgggacaaa gtcaaataaa gaacgattag aaggaaggca
    23821 aagaagaggt gttttgttct tgctttcctt tcttagaaag gatcatcagt gaataaacaa
    23881 gcctttaaag aggatttttt taaagttatc ttctttctca gtgcagcgat ggcaattatt
    23941 gctatttgtt taatctgtat ctttattttt agtaatggcc ttccctttat tgctaagtat
    24001 ggtatgagag cctttttgct aggaaatgat tggtcaccgt caaatcagcc ggcaagctat
    24061 ggtattttgc cgatgattgc agggtctttt gtcatcacac ttggtgcaat ggtgattggt
    24121 gtgccaacag gtatattgac ctcagttttt atggtttact attgtcctaa agcatgctat
    24181 ggctttttaa agtcagctgt taatctgatg gcagccattc cgtctatcgt ttatggcttt
    24241 tttggtcttc aagtgctagt gccttggatt aggagctttg ctggtaatgg catgagtgtg
    24301 ctgactgcct ccttgctctt aggaatcatg attttgccaa cgcttatcag tctttcagag
    24361 tctgctatca gagctgttcc aaaggcttat tattcagcta gtcttgcact gggagccagt
    24421 catgaaagga gtatttttcg agtgatcctg ccagcagcca aatccggcct tttttccgct
    24481 cttattttag gatttggtcg tgccattggt gagacgatgg cagttatttt ggtagcagga
    24541 aaccagcctg tgctgccatc aggattattt gagggcacaa gaaccatgac gacaaatatt
    24601 gtcctagaga tggcatatgc ttctggtcag catagagagg ccttgattgc aacatcggct
    24661 gtcctctttg gctttattct catcattaat gcttgctttg cttatgtgaa aggaaaatca
    24721 gctcatgact aactatttac taaaagccct ggtctatctt ttgtcgctat tgacctttgg
    24781 ctccttattt ttgattattg cctttatgct gataaaaggc ttgcctagtc tgtcgttatc
    24841 cttattttca tggacctata cctctgacaa tgtttctcta atgccgtcga ttatctcaac
    24901 tgttagtcta gttttaggca ccttagtgct agccttgccc attggtgtct ttgctggctt
    24961 ctatcttgtg gaatacgcta agcaggactc actatgggta agggcaatac gtcttgcagc
    25021 tgatacgcta tcagggattc cttcgattgt ttttggtctt tttggcatgc tgttctttgt
    25081 ggtttttttc ggcctgcaat attctctttt atcaggtatt ctgacgtctg taatcatggt
    25141 gttgccagtt atcattcgat caacagaaga agcgctcctc tctgttagtg atcacttgcg
    25201 tcaggctagc cttggcttag gagcaggtaa gctaaggacg atttttaaaa tagtgctgcc
    25261 ggctgcaatg cctggtattc tagccggggt aatcctagcg attggacgtg ttgtgggtga
    25321 gacagcagcc ctgatgtata ccctaggcac ctctaccaat acgccaacca gcctcatgtc
    25381 atcaggacgc tcactagctc ttcacatgta catgctgtct agcgaagggc tacatgtcaa
    25441 ggaagcttat gcaacgggtg ttatcttact cataactgtc ttgctgatca atgccctatc
    25501 aagcttatta tcacgccgat tagtgaaagg agtcgtctaa aatgggagct ttttcaacca
    25561 agcagcttaa tgtcttttat ggagcatttc aggccttaaa ggatatctcc attgacatac
    25621 cagaaaatca gatcacagcc ctgataggtc cctctggctg tggcaaatca acctttttaa
    25681 aaaccctaaa tcgcatgaat gacttgattc cttcctgtcg tatcgaagga gaggttctct
    25741 tagacaatca agacatctat gctaaagcaa taaacctcaa cagtctgcgt aagcgtgttg
    25801 gtatggtctt tcagcagccc aacccatttg ccatgtctat ttatgataat gtggcttatg
    25861 gtcctaggac acatggcctt aaggacaaga aaactctaga tcagctggta gagcagtcct
    25921 tgagaggagc agccatttgg gacgaggtca aagacagctt aaaaaagagt gccatgtccc
    25981 tatcaggtgg acagcagcag cggctttgca ttgcaagagc gcttgctgta gcacctgatg
    26041 tgttgctcat ggacgagcct acctctgctc ttgatcccat ttctacctta aaaattgagg
    26101 acttggttca gcaattaaag caggattaca cgattatcat cgttacccac aacatgcagc
    26161 aggcttcacg catgtcagat aaaacagcct ttttcctcac aggagatatt tgtgaatttg
    26221 gcgatacagc tgaactattt acaaagccaa aggacaagcg tacagaggat tatatttccg
    26281 gacgcttcgg ataagaaaag gactaggcga tgaaagagca attggaatga gggctaaatc
    26341 tctcctcaat tggtgttttg atgatgtcag atcagtatcc tattagcgtg gaagcttctc
    26401 tcttacttcc tgtagagtga agcttttttg ctttctttga taagcacgat ctagctattt
    26461 tcagacaaag gttactggta ttagaaatat atatatatat atattagtaa actataatct
    26521 tattaatatt atataataac tacataaaaa aacaaatagg agtcatatca tgaaaaaatt
    26581 actattaact agtgctgcag cgctagcctt agcaacagta gcagttagca caacaaaagt
    26641 agaggcgttt tctcgtgggc atgttataga gcatacgatt aacgacacca agtcgcttag
    26701 tgcagcgcgc tgggggtcaa gactgcaaat ccttaatctg ttaacacgat ttaagcataa
    26761 actaggagag gatggcttta ggtcttataa cagacaattc agagctaggg taggtgcagc
    26821 aaaatcagta agtgaaattg atgaacttta taataagttt gaaaaggagt tggaagagtt
    26881 agaagatctc acttaatttt gactaaccac taagtagcta aaagacgatt tccgtttgga
    26941 gatcgttttt tcttagcctt tagaagtatc tgaaaagata agttttgttt tcttgacact
    27001 tatttgtcat aaagctttta tcttgttcta tccctctttc tttgtgctat aataagaact
    27061 gttatggaaa atatgaatca tcaaaacatt tcagaagcgt tgggggtcac cccaaaacag
    27121 attagtcaag tgcttaccct taccgctgag ggtaatacca ttccctttat tgcgcgctat
    27181 cgtaaggaag ctacaggtaa ccttgatgaa gtggtgatca aggccattat tgatatggat
    27241 aagtccctca cacagcttag ggagcgtaaa gacaccattc ttgctaaaat cgaaggacaa
    27301 gggaaactaa cagctgccct taaggaagct atagaagcag ctgataaatt ggctgaccta
    27361 gaggagcttt atttgcctta caaggaaaag cggcgtacca aggcaaccat tgctcgagaa
    27421 gccggcttat ctggactagc tagactgatc cttcaaaatg cacaagacct agaaactaag
    27481 gcagaggcct ttatcacaga aggtttttcg gatccacagg cagcccttgc tggagctgtt
    27541 gatattttgg tcgaagccat gtcagaggat agcaggctaa ggtcctggac ctataatgag
    27601 atttggaagt atagccgtat aacctctagc ctaaaggaag ccagcttaga tgacaagcag
    27661 gtctttcaga tttactatgc gttttctgag acggtatcta acatgcaggg ctacaggacc
    27721 ctagctctca atcgtgggga aaagctaggc gtattaaagg tatcctttga gcatcatata
    27781 gacaaaatgc tgcgcttttt cagccttcgc tttaaggagc acaatgctta tattgatgat
    27841 gttattaacc aaacaatcaa gaaaaaaatt gttcctgcta tggaacgacg tatccgcaca
    27901 gaattaactg aaatggctga ggacggtgct atcaagctct tttcggaaaa tttgcgtcat
    27961 cttttgctaa tttcaccact aaagggaaaa atggtgctgg gctttgaccc ggcctttagg
    28021 acaggggcca aattagcggt gattgatccg actggaaagc tgttaactac tcaggttatc
    28081 tatccggtgg caccagctaa tcaagctaag attcaagcag caagagtagc tctagctcag
    28141 ctcatcactg actatcagat tgatattatt gccattggta atggcacagc cagtcgtgag
    28201 agtgaagcct ttgttgcaga ggtgctaaag gattttccag aaacctctta tgtcattgtt
    28261 aatgaaagcg gagcttcggt ttattcggcc tcagagctag cccgccatga atttccagag
    28321 ctgacggttg aaaagcgctc agccatctct attgcgcgtc gcttgcaaga cccgctagca
    28381 gagctggtca aaattgaccc aaaagcaatc ggtgtcggac aataccagca tgatgttagt
    28441 cagaaaaagc tatctgagca tctggatttt gtcgttgata ccgttgttaa tcaggttggg
    28501 gttaacatca atacagctag tccagcccta ctggctcatg tttcagggct aaataaaacc
    28561 atttctgaga atatcgtcag gtatcgtgaa gaaaatggag agatcacctc acgtgctgag
    28621 atcaaaaagg tccctagact aggcgcaaag gcctttgagc aggcagcagg cttcttgcgt
    28681 attcccaatg ctaagaatat attagacaat acaggcgttc acccagaagc ctatccggct
    28741 gtcaaaaagc tctttcaatt acttgcgatt aaagacttag atgagcctgc aagggccaaa
    28801 ttacaggcgg ttaatcttga ggaaatggca gagcaattga cgcttggtca agaaacgctc
    28861 aaggatatca ttgctgattt gctgaagcca ggaagagact tgcgtgatga ctttgaagct
    28921 cctgttcttc gaaaggacat tttgagtgta aaggatctgg ctgttggtca aaggctagag
    28981 ggaactgtta gaaatgtggt tgacttcggt gcttttgttg atattggtgt acatgaggac
    29041 ggtttgattc acatttcaga gatgagtgag gcctttgtca atcacccaag tcaggtcgtt
    29101 tctgtcggag atttagtcac tgtttgggtt tctaaggttg acttagaccg ccacaaggtc
    29161 aacctaagct tagtgccgcc tcgtgagtct gactgattat gttagagagg tctcgctagc
    29221 tgattttgga aagcccttta agcatcaggc ttcttggaac agacgactaa gaacaacagg
    29281 cggacgtttt tttccaaagg atggtcatct ggatttcaat cccaaaatct tagaggagca
    29341 tggggagact gtctttagac agatcgttag gcatgagctt tgtcattatc acctctattt
    29401 tgaggggctg ggctttcggc ataaggatca agcctttaag gagcttctag accaagtaga
    29461 cggtctgaga tacgctccaa aattacagtc acatcaagct aattacctct acatctgtca
    29521 agattgcggc caagcttatg accgaaaacg tcctatcaat ctggcggtat ttgcctgcgg
    29581 caggtgtcat ggcaggctca ttgaaaaaaa tcagtcgtaa ggctgatttt attttgctaa
    29641 aaaaggaata aactagtatc atagaataag gaggcgagga gacatggaat ctaaatttta
    29701 taagcaacga aagcataagc tagtggctgg agttatctct ggtttagctg ataaatacgg
    29761 ctgggatttg cccctagctc gtgtgcttgc cgccttattg atctatttta ctcgctttgg
    29821 ggttgttatt tatattcttt tagccatctt cctaccatat aaagaggacc tacttgaaga
    29881 acgttacggg agaggaccaa gacgtcgcaa ggatgctgat gtcctaaatg atgaagatga
    29941 aggctggttt tggtaagacc acagcgagcg actattaaaa gcttgacagg aattttaata
    30001 gtgcctctag cgtgattatc agaaataaag ctggctgtag gcctttatct gatgagatag
    30061 ggccttttgt tgtttgtccg ctttaggcta gtgcctgctt taagtgagcc tgaggcagct
    30121 gttgcaggat tcttttttag tatgatcaag cactttgaaa gcttctttga aaaataagta
    30181 tttgtaaggg cttagatagt gatttatgat ataatattaa aaaaggagaa attatgacag
    30241 ttaccgttaa gatgttagtc acaaaggtca agcttgacgt tgtctatgca actgatgact
    30301 tgctagaaaa ggagataacg acctcagata tttcgcgtcc gggtcttgag atgaccggct
    30361 attttgatta ctatgcccca gagcggcttc agctgtttgg catgaaagaa tggtcctacc
    30421 tcactcagat gacctcacac aatcgctact cagtcttaaa ggaaatgttt aaaaaagaca
    30481 cgccagctgt gattgtatct aggggcctag ctatcccaga ggagatggtt caggcagcgc
    30541 aggaggaagg tattgctctg tttagcagcc gcgtatctac cagccgctta gctggtgaga
    30601 tgtcttattt tcttgatgct tccttagcag agcgaacaag tgtgcatggg gtgctgatgg
    30661 atatttacgg tatgggggtg ctgatccaag gtgattcagg tattggtaaa agtgagacag
    30721 gcttagagtt ggtcaagcgt ggccatcgct tggtggcaga cgaccgagta gatgtctttg
    30781 ctaaagatga ggagacgcta tggggggagc cagcagagat tttacgtcat ctccttgaga
    30841 ttcgtggtgt tggcattatt gatgtcatgt cgctgtacgg tgctagtgct gtcaaggatt
    30901 cctcacaggt gcagttggct atttatttgg agaattttga ggctggcaag gtctttgacc
    30961 gcttgggcaa tggcaatgaa gagattacct tttctggtgt cagtattcca aggattcgca
    31021 ttcctgtcaa aacaggtcga aatgtgtcag tggttattga ggctgctgcc atgaaccatc
    31081 gtgcgaaaga gatgggcttt gatgctacca aaacctttga ggagcgcctt acacgtttaa
    31141 tcagcaaaaa tgaggagggc aaatgatcaa tccaatagcc tttaagcttg gtcctcttag
    31201 tcttcactgg tatgcggttt gtatcttggt gggattactt ttagcggttt atttggcagc
    31261 caaagaagcc ccgcgaaaaa aaatgaccag tgatgatatt attgatttta ttctgattgc
    31321 ctttcctttg gcaattattg gagcaagaat ctattatgta gcctttgaat ggtcctatta
    31381 ttctcagcat ttgagtgata tctttgctat ttggaatggt gggattgcca tctatggcgg
    31441 cttgataaca ggtaccattg ttctctttgt ttattgctac tataaggtgc tgaatcctat
    31501 ccatttctta gatattgcag cgcctagtgt catgcttgct caggccatcg gcagatgggg
    31561 aaatttcttt aaccaagagg cctatggcag ggctgtcagc cagctcaatt acctgcctag
    31621 ttttattcgc cagcagatgt ttatagatgg cagctatcgt gttcccacct ttttatatga
    31681 gtccatgtgg aacctgattg gctttgtcat tatcatggtg tggcggcgta agcccaggtc
    31741 attagtagat ggggatatta tctcatttta cctgatttgg tatggctgtg gtcgattggt
    31801 gattgagggc atgcgaacgg acagcctgat gcttttagga attcgtgttt ctcaatacat
    31861 gtcggtgctg ctcattatca ttgcgattgt ttttatcttt aaaaggcatc gacaaaaggg
    31921 aatttcttat tatcaagaat agggatagaa agaggagacg tttatgaatt tagtgggcat
    31981 ttcattgctg ataatcgcat tagcctttgt tgctctggtt atttttttga ttgtggtgtt
    32041 aaaaaaggtg tcagaggcag ttgatgaggc taaaaaaacc attaccgttt taacgagtga
    32101 tgtcaatgtt accctttatc aaaccaatga aatattagct aaggctaatg tgctggtaga
    32161 tgatgtgaat ggtaagatga caacaataga tcctctcttt gttgctattg cagatttgtc
    32221 agaaagtgtt tctgatttga atgtgcaggc cagacacctt ggacgtcggg cgacaaatgc
    32281 cacaagcaat gctgcaaagg tgggtaaagt agctcttgtc ggcaaggtcg cttctaaatt
    32341 atttggtaaa aaggagaaaa ggtcatgagt aattttttta aaacgttggt gattggtgta
    32401 gcttcaggag cagctaccgc ttatttcttg tcaactgaaa aaggaaaggt cttgaaggct
    32461 cgcgcacaaa gggcctatga agcctatcgt caaaatcctg aggaatatca tcaaatggct
    32521 aaagaaaaag gaagtgagta cagtcagctg gctcgccata cctttaatga tttaaaaacc
    32581 aggtttgaat caggggatat gaccactgat caggtgtttg attttatcaa ggaaaagacc
    32641 agccaatttg ttcatcaggc aaaggaagct gcttcagagc atgacaaggc tgatgatgtg
    32701 attattgatc tggatgaaga ggatattatt atcaactatc ctgaagatga ttcagaaaaa
    32761 gaagcagcta gcaataagtc tgaagaataa taaggcaaaa ataagggctc tctcagctat
    32821 ggagggcctt ttgtgatgtg ggctactcgt ttattcaaga aaataggcaa taagagtaat
    32881 gaaaaaagag cttagcgaag ccaagctcta actgtttatg acattaataa cgtgatggcc
    32941 tttgaaagaa aggaagtgat ggctaggctg atagcactag caattagaaa ggcccaaacc
    33001 ggtgccaaat tcatgacaag aaggacaaat gcaaacaaga cagtgattaa actaaaaaca
    33061 gcaatacggg caaaaaaaat aagttccttg agcttgctac tgtgtccatt gaggtcttga
    33121 aactcttgaa atttttgctg cgagacctgc tcttgcttct gctgcttgag ctgccgctgc
    33181 tccaatggtg taggcatagt cctctccttt cccgtaagat acccaaccat tttaccataa
    33241 aagctgatgg ttgtcatctt ttttttgaag gcttctcgtt
//
LOCUS       DARYNN010000021        31792 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.021, whole genome shotgun sequence.
ACCESSION   DARYNN010000021 DARYNN010000000
VERSION     DARYNN010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31792)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31792)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31792
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.021"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(14..1408)
                     /locus_tag="TVB59_000938"
     CDS             complement(14..1408)
                     /locus_tag="TVB59_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEL1009845.1"
                     /translation="MTIFRKKRQAINKTEMNRHLKMLDLIFLGLGSMVGTGIFTITGI
                     GAANYAGPALTISIILSAIAISILALFYAEFASRIPANGGAYSYVYATLGEFPAWIVG
                     WYIIMEFLTAISSVAVGWGSYLKGLLANYGLQLPNALNGTFDPQKGTYVDLLPVLVML
                     LVTAIVLMNSKAALRFNSFLVLLKFSALALFVIVGLFFIDVANWSHFAPYGFGQIYGG
                     KSGIFAGASVMFFAFLGFESISMTVDEVKEPQKTIPRGIVLSLTIVTILYVIVTMVLT
                     GIVHYTKLDVPDAVAFALRSIGLYWAADYVSIVAILTLITVCISMTYALARTVYSISR
                     DGLLPRALCQITEKTRIPRNATLVVGALSMICAGIFPLASLAEFVNICTLAYLVIMSF
                     AIIKLRKNAGEPQRGEFKTPFVPLLPILAIIICVTFMSQYMVFTWIAFGISTILGIVV
                     YACYGYTHSQERRN"
     gene            complement(1567..3537)
                     /gene="ftsH"
                     /locus_tag="TVB59_000939"
     CDS             complement(1567..3537)
                     /gene="ftsH"
                     /locus_tag="TVB59_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEL1009846.1"
                     /translation="MKNNKNNGFVKNSFIYILMIVIVVAGFQYYLRGTSTQSQQISYS
                     KLIKHLKAGDIKSLSYQPSGSIVEVKGKYEKPQKVSIDTGLSFLGNSAATEVTEFTAL
                     ILPSDSVLKEMTSVADKNGTDITVKQESSSGAWITFLMSFLPIVIFAAFMMMIMNQGG
                     GARGAMSFGKNKARSQAKGDVKVRFTDVAGAEEEKQELVEVVDFLKNPKKYKALGARI
                     PAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAKK
                     AERAIIFIDEIDAVGRRRGAGMGGGNDEREQTLNQLLIEMDGFEGNESIIVIAATNRS
                     DVLDPALLRPGRFDRKVLVGRPDVKGREAILRVHAKNKPLAEDVNLKVVAQQTPGFVG
                     ADLENVLNEAALVAARRNKTKIDASDIDEAEDRVIAGPSKKDRSISQREREMVAYHEA
                     GHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKDDLKEQLAGLMGGRV
                     AEEIIFNAQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMMPGQLSPEKS
                     YSAQTAQMIDDEVRDLLNEARNKAADIINDHRETHKLIAEALLKYETLDAAQIKSIYE
                     TGKMPNDPENDEAEVHALSYDEIKDKMTEAKE"
     gene            complement(3559..4101)
                     /gene="hpt"
                     /locus_tag="TVB59_000940"
     CDS             complement(3559..4101)
                     /gene="hpt"
                     /locus_tag="TVB59_000940"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012961310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEL1009847.1"
                     /translation="MLEQDIQKILYSENDIIQRTKELGEQLTKDYHGKNPLMVGVLKG
                     SVPFMAELMKHIDTHVEIDFMVVSSYNGGTTSSGEVKILKDVDTNIEGRDVIFVEDII
                     DTGRTLKYLRDMFKYRKANSVKIITLFDKPEGRVVDIEADYVCYNVPNEFIVGFGLDY
                     AENYRNLPYVGVLKEEVYSK"
     gene            complement(4106..5389)
                     /gene="tilS"
                     /locus_tag="TVB59_000941"
     CDS             complement(4106..5389)
                     /gene="tilS"
                     /locus_tag="TVB59_000941"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEL1009848.1"
                     /translation="MTYQHIYNIIKKKAYFDAHQAVLIAVSGGVDSMNLLHFLHAFQA
                     KLQIRIGIAHVNHKQRPESDDEEAYLRSWAKKHAIPIYVAYFQGAFSENAARHLRYQF
                     FEEIMQQEHYSALVTAHHADDQAETILMRLIRGSRLRHLAGIREVQPFANGQLIRPFL
                     TVSKAELPNPFHFEDHSNDSMAYFRNRVRHHYLPDFKRENPQATQSLIDLSAESRLLL
                     QAFDDLTKGLEFHRLNCFLAQSAAVQFFLLQHYLETFPQLAIKKSQFDDLLHIIRRQK
                     QGIYPIKNTYCLLIEKESFAIKKIIPKTDLNREFKMVSYGDSLNYRGYRFVFSGSLTD
                     KGHDIAIPLYSLSPVTLRHRQAGDRLFLGEFSKKLRRLFIDGKFTSEQRQNAIVGEQA
                     GVIIFVLVGDETYLRKASKHDIMLAKLYIDKLEKR"
     gene            complement(5386..6672)
                     /locus_tag="TVB59_000942"
     CDS             complement(5386..6672)
                     /locus_tag="TVB59_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HEL1009849.1"
                     /translation="MKKLLAAMLMTFFVTPLTVISTEKIPVFSEATRYHLSQDIVSST
                     LYYSRIPTNPNVFEETVAYRDPELSVPKTMIAPDNRIVIKDVLLNKAAIPVFRLADDT
                     YLEASRQIVYEDIMFEQTAVDLDFWTQKKMTIYAEPYVLGVKTIASDSEPGRKVHASK
                     MAQTEHGTYYFIDHKGWVNQKELSPTDNRMLKVQEMLLQKYNKENYSIFVKQLNTQAS
                     AGINADKQMYAASISKLATLYSVQKKLKSGSLSEGKSLKYIDEVNHFYGDYDPTGSGK
                     ISKTADKKDYNVMELLKAVAQQSDNVATNILGYYLCNQYNQAFQSEIRALAGVDWDME
                     KRLLSSHAAANLMEAIYYQKGQIISYLSQTAFDDQRISKNISVPVAHKIGDAYDYKHD
                     VAIVYGDNPFILSVFTDKASYDDITAIADDVYSILK"
     gene            complement(6814..7185)
                     /locus_tag="TVB59_000943"
     CDS             complement(6814..7185)
                     /locus_tag="TVB59_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEL1009850.1"
                     /translation="MKKPSIVQLNNHYINEENIKKRFEEEEIQKRNRFMGWILVSMMF
                     LFILPTYNLVKGYVSLKKQGQQIITLEKEYRELEKKTKSEKQLAEQLKNDDFVKKYAR
                     AKYYLSREGEVIYPTPGLLPK"
     gene            complement(7172..7444)
                     /locus_tag="TVB59_000944"
     CDS             complement(7172..7444)
                     /locus_tag="TVB59_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEL1009851.1"
                     /translation="MRLDKYLKVSRLIKRRSVAKEVADKGRIKVNGILAKSSTDLKLN
                     DQVEIRFGNKLLTVRVLDMKDSTKKEDAAKMYDIISETRISSDEEA"
     gene            complement(7475..8986)
                     /locus_tag="TVB59_000945"
     CDS             complement(7475..8986)
                     /locus_tag="TVB59_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HEL1009852.1"
                     /translation="MRLNLEKLPHKTKQSSLLIVISGFMSKLLAASYRIPYQNLVGDR
                     GFYAYQQIYPLLGIISALGLTALPNVIASMAQKKKQLQLAALFKLQCYTSFLLSGILV
                     LSHKALASWMGAQQLAPSIVITAMVLLIVPFISFYRGLAQADMNMAPTALSQVLEQII
                     RVAIIIVAALCYRVLGWTVYLTANVAAFGNLVASLVILAYLKRHSAYSLKSFLSGDTV
                     AIRDLTSLGLPTLVFLLFSIYLLVFQLIDSLLVKNILVSSGLSEITAEMTKGVYDRGQ
                     PLLQFGLIFSTALFTAYLPNLTVLFHIKRESYREQSQCFFEFIFYFSLTLTVGFISIL
                     HLMNRALFEDNKGWLALVVYLMIIAVSSMIQFFHQKCFIEDHIKQSLLILLFGFLLKL
                     GLTPILTYYYAIVGSSLSTLIPLLVVLLLYAVLADIDFKAIVNAKYGLALVIMLMCVL
                     TSQYCLPLSGRLGALISLLVSSAVGLSSFLIACKKLGVFKEKLWSFLPFVKEK"
     gene            complement(8955..12449)
                     /gene="mfd"
                     /locus_tag="TVB59_000946"
     CDS             complement(8955..12449)
                     /gene="mfd"
                     /locus_tag="TVB59_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEL1009853.1"
                     /translation="MDILELFNQNKSIQTWQCDVTSLKRQLVMGLSGSSKAAAIASAY
                     LSFQGKLVVVTSTQNDMEKLAGDLSALLDEGSIFQFFADDTAAAEFIFSSMDKTISRI
                     EALAFLSNPEARGILVISLAGLRILLPSPKTFQQGQIDLAVGVDTDLDNVVKKLVKIG
                     YQRVAQVLSPGEFSRRGDILDVYEVTQDLPVRIEFFGDEIDGIRSFDIESQKSLQKKD
                     STSIKPASDMIFEPEDFDRASHNLEKQLQLAKAEHKGYLEELLTVTKEGLKHKDIRKF
                     QSLFYDNEWTILDYLPKGTPVFFDDFQKLVDRNAKFDLELAHLLTDDLQQGKSLPFLH
                     YFADNYRELRHYKPATFFSNFHKGLGNIKFDKVYSLTQYAMQEFFNQFPLLIDEIKRY
                     QKSGATVLLQVESHQAYERLAKSLEAYQCQLPLVSADAIVLHQAQIIIGHLAGGFYFA
                     DEKLVLITEHEIYHKRLKRRARRTNMSNAERLKDYNELSKGDYVVHSVHGIGRFLGIE
                     TINIQGVHRDYVTIQYQQSDRISLPVDQLESLSKYVSADGKEPKINKLNDGRFQKAKQ
                     RVKKQVEDIADDLLKLYAERSQQKGFQFSPDDELQRAFEEDFAFVETDDQVRSIKEVK
                     KDMESVRPMDRLLVGDVGFGKTEVAMRAAFKAIGDHKQVAILVPTTVLAQQHYENFRE
                     RFENYPVEIAVLSRFRSKKEQSESLERLKKGQVDIIIGTHRLLSKDVIFSDLGLIVID
                     EEQRFGVKHKETLKELKTKVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPVQ
                     TYVLENNPGLIREAIIREMDRGGQVFYVYNKVDTVDKKVAELQELVPEASIGFVHGQM
                     SDIQLENTLMDFINGDYDVLVATTIIETGVDISNVNTLFIENADHMGLSTLYQLRGRV
                     GRSNRIAYAYLMYKPDKVLTEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNILGA
                     SQSGFIDSVGFDMYSQLLEQAIASKQGRALTRQKGNAEINLHIDAYLPSDYIKDERQK
                     IDIYKRIREIDSRAAYSDLQDEIMDRFGDYPDQVAYLLEIGLLKYYLDTAFAELVEKR
                     DHQVMVRFEVASLQYYLTQDYFEALSKTSLKARISEHQGKIEIIFDVRRQKDHVILEE
                     LILFGETLGEIKSRKASS"
     gene            complement(12452..13021)
                     /locus_tag="TVB59_000947"
     CDS             complement(12452..13021)
                     /locus_tag="TVB59_000947"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEL1009854.1"
                     /translation="MVKMIVGLGNPGSKHQQTKHNVGFMAVDRLVKDLDVSFTEDKTF
                     KALIGSTFINQEKIYFVKPTTFMNNSGLAVRALLTYYNISTKDLMVIYDDLDMAVGKI
                     RLRQKGSAGGHNGIKSIIAHIGTQEFDRVKIGIGRPSHGMSVINHVLGKFDTDDMITI
                     NIALDKVDKAINYYLQEKSIEKTMQQFNG"
     gene            complement(13180..14295)
                     /gene="ychF"
                     /locus_tag="TVB59_000948"
     CDS             complement(13180..14295)
                     /gene="ychF"
                     /locus_tag="TVB59_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEL1009855.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTELITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESINKRYARVEKMARTQKD
                     KDSVAEFAVLEKIKPVLEEGKSARTISFTDDEQKIVRQLFLLTTKPVLYVANVDEDKV
                     AIPDAIDYVKQIRDFAATENAEVVVISARAEEEISELDDEDRSEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGIKAPQAAGIIHSDFERGFIRAVTMSYDD
                     LIKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            complement(14379..14744)
                     /locus_tag="TVB59_000949"
     CDS             complement(14379..14744)
                     /locus_tag="TVB59_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1009856.1"
                     /translation="MMTKFAEQLKKYRLEKQLSQDALAEKLFISRQAISKWENGDATP
                     DLENLVTLAAVLEVTLDELVTGKEPAIKVIKKTEKPMNVWEFLTEESKRPMRKGDLLM
                     LLLVVIVLLGVYFIVIHFS"
     gene            complement(14865..15062)
                     /locus_tag="TVB59_000950"
     CDS             complement(14865..15062)
                     /locus_tag="TVB59_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEL1009857.1"
                     /translation="MYQVGSLIEMKKPHACVIKETGKKANQWKITRVGADIKLQCTNC
                     NHVIMLSRHDFERKMKKVLQP"
     gene            complement(15140..16276)
                     /gene="dnaN"
                     /locus_tag="TVB59_000951"
     CDS             complement(15140..16276)
                     /gene="dnaN"
                     /locus_tag="TVB59_000951"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEL1009858.1"
                     /translation="MIQFSINRALFIQALTATKRAISSKNAIPILSTIKIEVNPSDIT
                     LTGSNGQISIENTIPVSNENAGLLITSTGAVLLEASFFINIISSLPDVSLEFKEIEQH
                     QVVLTSGKSEITLKGKDVSQYPRLQEVSTENPLILNTRLLKSIIAETAFAASMQESRP
                     ILTGVHITLSQHKNFKAVATDSHRMSQRLITLEKTSADFDVVIPSKSLREFSAVFTDD
                     IETVEVFFSASQMLFRSDYISFYTRLLEGNYPDTDRLLMKQFETEAVFNTQSLRHAME
                     RAFLISNATQNGTVKLEIEANRISAHVNSPEVGKVNEDLDVVSQAGNDLTISFNPTYL
                     IEALKAIKSETVKIHFLSPVRPFTLTPGDDEESFIQLITPVRTN"
     gene            complement(16433..17785)
                     /gene="dnaA"
                     /locus_tag="TVB59_000952"
     CDS             complement(16433..17785)
                     /gene="dnaA"
                     /locus_tag="TVB59_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEL1009859.1"
                     /translation="MTENEQIFWNRVLELAQSQLKQATYEFFVHDARLIKVDNHVATI
                     FLDQMKELFWEKNLKDVILTAGFEVYNAQIAVDYVYEDDLMIEQQHQGQQGYTEQAFQ
                     QLPAVQSDLNPKYSFDNFIQGDENRWAVAASIAVANTPGTTYNPLFIWGGPGLGKTHL
                     LNAIGNSVLLENPNARIKYITAENFINEFVVHIRLDTMDELKEKFRNLDLLLIDDIQS
                     LAKKTLSGTQEEFFNTFNALHNNNKQIVLTSDRTPDHLNDLEDRLVTRFKWGLTVNIT
                     PPDFETRVAILTNKIQEYNFIFPQDTIEYLAGQFDSNVRDLEGALKDISLVANFKQID
                     TITVDIAAEAIRARKQDGPKMTVIPIEEIQAQVGKFYGVTVKEIKATKRTQDIVLARQ
                     VAMFLAREMTDNSLPKIGKEFGGRDHSTVLHAYNKIKNMIGQDESLRIEIETIKNKIK
                     "
     gene            complement(18018..18791)
                     /locus_tag="TVB59_000953"
     CDS             complement(18018..18791)
                     /locus_tag="TVB59_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEL1009860.1"
                     /translation="MTEILMHIPIEDIVANPYQPRLQFNQKELEELAHSIQANGLIQP
                     IIVRKSDVFGYELVAGERRFKAAKLAGLQKIPAIVKEISTLESMQQAIVENLQRSNLN
                     AIEEAKAYQLLIDKNKMTHEDIATYMGKSRPYISNTIRLLQLPDVIRQAIEDGTISAG
                     HARALLSLSTPKEQELYFHNILDQGLSVRQIEQLVKTKHPPKKRNKHKTIFVKSLEKE
                     LSKSLGLPVALSLQKNDSGQLQLSFSNQEELNRIINKLL"
     gene            complement(18911..20134)
                     /locus_tag="TVB59_000954"
     CDS             complement(18911..20134)
                     /locus_tag="TVB59_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HEL1009861.1"
                     /translation="MLKSKNILKPLWVLAIGFLGGLLAALVVNGFSQNSLTSSNAKGA
                     TTTSNVSFNNTTDTTKAVKVVQDAVVSVINYQKAASPAISNPYINLFGEENDTSAVQK
                     EDELSIHSEGSGVVYKKEGNTAYLVTNNHVIEGAQRIEILTADGSKIVGELVGADTYS
                     DLAVVKVAADKIKTIAKFADSTKINVGEVAIAIGSPLGTKYANSVTEGIVSSLSRTVT
                     SRNEAGETISTNAIQTDAAINPGNSGGPLINIEGQVIGINSSKISSTPTGSGGAIEGI
                     GFAIPSSDVVTIINQLESNGAVIRPALGITMVNLSNLSTNALIQLNIPTSVTSGVVVA
                     STQDGMPALGKLEQYDVITEVDGKEVSSISDLQSVLYSHEINDTIKVTFYRGTAKKKV
                     DIKLTKTTKDLTKKQ"
     gene            20344..20823
                     /gene="rlmH"
                     /locus_tag="TVB59_000955"
     CDS             20344..20823
                     /gene="rlmH"
                     /locus_tag="TVB59_000955"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEL1009862.1"
                     /translation="MKIKLICVGKLKEAYLRDGIAEYQKRLSRFCQCDIIELADEKTP
                     DKASHAEKQQIMAKEADRIKKKLGQRDFVIALAIEGKQLASEQFSHLLSEVTVKGYSD
                     IAFVIGGSLGLDQSIKNRANLLMSFGLLTLPHQLMRLVLIEQVYRAFMIQQGSPYHK"
     gene            complement(21123..21196)
                     /locus_tag="TVB59_000956"
     tRNA            complement(21123..21196)
                     /locus_tag="TVB59_000956"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(21160..21162),aa:Arg,seq:tct)
     gene            21477..21548
                     /locus_tag="TVB59_000957"
     tRNA            21477..21548
                     /locus_tag="TVB59_000957"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21510..21512,aa:Glu,seq:ttc)
     gene            21581..21654
                     /locus_tag="TVB59_000958"
     tRNA            21581..21654
                     /locus_tag="TVB59_000958"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21615..21617,aa:Asn,seq:gtt)
     gene            complement(21915..24500)
                     /locus_tag="TVB59_000959"
     CDS             complement(21915..24500)
                     /locus_tag="TVB59_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEL1009863.1"
                     /translation="MTKPKAWSLVYDIASFLLPFLIMFFVLLSMGISYGSEKTILASD
                     GFHQYVIFAQALRNILHGADSIFYTFTSGLGVNFFALASYYLGSLLSPLVYFFNLQSM
                     PDAIYLLTLIKFGLIGLAAYFSFHRIYPKIKPFLVLTLSVSYSLMSFLTSQLELNNWL
                     DVFILLPIVLLGLYRLITQTKPLLYYSSLSLLFIQHYYFGYMVAIFIFLLFLVNLISL
                     DTWKRRLRACLSFTSVSILSALTSAFILIPAYLDLTAYGETLSPINQIIIKPIGAFDL
                     LAKLSLGAYDTTKFNAIPMIFIGLLPSLLSIVFFTLKSISWRLRLGYGLLLGLIMASF
                     YLQPLDLFWQGMHGPNMFLHRYSWSFSIIIIILACEALSRQKDITNTRIIFAFILLSC
                     LLTLPYLTMDQYSFLQPSLLILSLAFLAAYLILLLSMQKTSVPMPFLIFFTLLFSCLE
                     TSLNTYYQLNGIHHEWVFPSRKGYSRALQDIDRLVKKTADSNDQFFRLEQLLPQTGND
                     SMKYSYNGISQFSSIRNRHSSSLLDRLGYQSAGTNLNLRYQNNTLIMDSLLGIKYNLS
                     YHQLHKFGFSRIASSHHTTLYQNHYSSNLAILTDNIYKDVKLTVNTLDNQTKLLNQLS
                     GKRLTYFQLEPSKLISNAQVFNGRISGEAAENTSTTIVHYQVTVPNHRQLYLSLPNIS
                     FSNHNATAVRIRIDDQTYEYTTDNAFSFFDLGYFEKGRTLTLAIMFPKNKNISFATPH
                     FYSLNSDNYLAAMNAINQKEVTTYTRSNQVISHYKAKSEGSMIFTLPYDKGWTARLNG
                     RPVALKKAQGGFIRIDVPKGSGKLVLTFVPNGFTLGLLLSFIGILLYSFLHYYLLRQT
                     AKLKA"
     gene            complement(24623..26242)
                     /locus_tag="TVB59_000960"
     CDS             complement(24623..26242)
                     /locus_tag="TVB59_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1009864.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTAGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEEERAIDVVIMGNEQLYSIMKEKDAI
                     YMKPDFSEEDGVRAAELEGSFAELGGWEAESEASQLLQNLNIPEELHYQSMSELTNGD
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSISWLEDFLIDFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLFVGNYDFWKQSSELAARLQADRNAKAEEKIKELQEFVARFSANA
                     SKSKQATSRKKMLDKIELEEIIPSSRKYPFINFKAEREMGNDFVTVENLSVTVDGDKI
                     LDNISFILRPGDKTAIIGQNDIQTTALMRALADDIDYEGTIKWGVTTSRSYLPKDNSR
                     DFASDESILEWLRQFAAKGEDDDTFLRGFLGRMLFSGDEVKKSVNVLSGGEKVRVMLS
                     KLMLLKSNVLLLDDPTNHLDLESISSLNDGIKDFKESVIFTSHDHEFIQTIANHIVVI
                     SKNGVIDRIDETYDEFLENKDVQAKVAELWK"
     gene            complement(26322..27194)
                     /locus_tag="TVB59_000961"
     CDS             complement(26322..27194)
                     /locus_tag="TVB59_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEL1009865.1"
                     /translation="MKKRVMDLLFVTIGSFITAIGFNTMFVDNNIASGGMVGISVVIK
                     ALFGISPSLFLMLSNIPLLILCYFFLGKQNLIKTLYGSWIYPIAIRLTSQLPTLTHNQ
                     LLAAIFGGIICGIGLGMVFWGNSSTGGTGILTQILHKYSPLSLGVAMTIVDGISVLMG
                     FIALSADDVMYSTIGLLVIGYVISVMENGFDSSKNVMIISKEYQAIKAYITGVMDRGV
                     SKIPIRGGYTTSDKIMLMAIVSGYELPALQEKILEIDDTAFIVVMPAAQVMGRGFSLT
                     KHYKLEDKDVLLPM"
     misc_binding    27316..27555
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            27611..28633
                     /gene="trpS"
                     /locus_tag="TVB59_000962"
     CDS             27611..28633
                     /gene="trpS"
                     /locus_tag="TVB59_000962"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEL1009866.1"
                     /translation="MTKPVILTGDRPTGKLHLGHYVGSLKNRVSLQNENKYKMFVFLA
                     DQQALTDHAKESEMIRESIFNVALDYLSVGLDPSKSTIFIQSQVPELAELTMYYMNLV
                     SLARLERNPTVKTEIAQKGFGESIPAGFLVYPISQAADITAFKANVVPVGNDQRPMIE
                     QTREIVRSFNHTYKTACLIEPEGLYPENEKAGRLPGLDGNAKMSKSLGNGIYLSDDAD
                     TVRQKVMSMYTDPNHIRIEDPGQLEGNMVFHYLDIFGQKEDKADIEAMKEHYQRGGLG
                     DVKTKRYLLDILERELAPIRQRRLEYAKDKGEVFRMLEAGSQKAQAVAAQTLSEVKVA
                     MGIRYF"
     gene            28834..30315
                     /gene="guaB"
                     /locus_tag="TVB59_000963"
     CDS             28834..30315
                     /gene="guaB"
                     /locus_tag="TVB59_000963"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEL1009867.1"
                     /translation="MSNWDTKFLKKGYTFDDVLLIPAESHVLPNEVNLKTKLAKNLTL
                     NIPIITAAMDTVTDSKMAIAIARAGGLGVIHKNMSIAEQAEEVRKVKRSENGVIIDPF
                     FLTPEHKVAEAEELMQRYRISGVPIVETLANRKLVGIITNRDMRFISDYNAPISEHMT
                     SEQLVTAEVGTDLETAERILHEHRIEKLPLVDDNGRLSGLITIKDIEKVIEFPHAAKD
                     EFGRLLVAAAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDK
                     TLIAGNIATAEGARALYDAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIYQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAASDIVFQMLGGIRSGMGY
                     VGAGTIRELHDNAQFVEMSGAGLIESHPHDVQITNEAPNYSMH"
     gene            30696..31088
                     /locus_tag="TVB59_000964"
     CDS             30696..31088
                     /locus_tag="TVB59_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1310 family protein"
                     /protein_id="HEL1009868.1"
                     /translation="MNRFLKISLLIVGVIVIMLGMEVKHRMDIYDQIKQEEIKIAQSK
                     EAIVIYEQELKWLDPNALTNEGTIKSYSIDLDSITLNPMGGFSIALHINKNPKYKYRI
                     SLMWNTPMRDLCVGGSSLSPELQELLDR"
     gene            31163..31564
                     /locus_tag="TVB59_000965"
     CDS             31163..31564
                     /locus_tag="TVB59_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1310 family protein"
                     /protein_id="HEL1009869.1"
                     /translation="MKTLLKLIVFIVGTLVLMLGMEVKHRMDTYDQIKQVELKNAHSK
                     EVIEMYEQELISMDPQALTDEGLIKSYTIDSDSLFINPMGGFSIHLIINDDPDIYLRV
                     GLGRYDMERNLEIDGIYRSEKLEKLLKGVER"
     gene            31561..>31792
                     /locus_tag="TVB59_000966"
     CDS             31561..>31792
                     /locus_tag="TVB59_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1310 family protein"
                     /protein_id="HEL1009870.1"
                     /translation="MKTLLKLIVFIVGALVLILGMEVKHRMDIYDQVKQVELKNAHSK
                     EAIDIYEKKLKRLDPQALTDEGLIKSYTIDSDS"
BASE COUNT         9891 a         6368 c         5850 g         9683 t
ORIGIN      
        1 tagttttgga catttagttt cttctttctt gcgaatgggt atagccatag catgcataga
       61 ctacaatacc aagtatagtg ctgataccaa aagcaatcca cgtaaatacc atatactgac
      121 tcataaaggt tacacagatg ataatagcta aaattggcaa tagaggcaca aaaggagttt
      181 taaactcccc acgttgaggc tctccagcgt tttttcttag cttaatgata gcaaaggaca
      241 tgatgacaag ataagcgaga gtacagatat tgacaaactc agcaagactg gctaggggga
      301 atattcctgc acaaatcata gataatgcac caacaactag ggttgcattt ctaggaattc
      361 ttgttttttc tgtgatttga caaagggctc ttggtaaaag tccatctcta ctgatactgt
      421 aaaccgttct tgctaaggca taggtcattg aaatacaaac tgtaattaga gttaaaatgg
      481 caacaattga gacataatct gctgcccaat ataacccaat actccttaaa gcaaaggcaa
      541 ctgcatcagg tacatctaat tttgtatagt gaacaatccc agttaaaacc attgtaacaa
      601 taacatataa gatcgttaca atcgttaagg ataatacaat acctcttgga attgtttttt
      661 gtggttcttt gacctcatct actgtcatgg aaatagactc aaagcccaag aaagcaaaaa
      721 acatgactga ggctccagcg aaaatacctg acttaccacc ataaatttgg ccaaagccat
      781 aaggcgcaaa atgtgaccag ttggctacat caataaaaaa taagcctaca atgacaaata
      841 aagccagagc tgaaaatttt aacagaacta aaaagctatt gaatcgcaat gctgcctttg
      901 aattcatcaa tacaatagca gtcactaata gcatcactag cactggaagt aaatccacat
      961 aggtcccctt ttgaggatca aaggtaccat ttaaagcatt gggcaattgt aagccataat
     1021 tagccagtaa gccttttaaa tagctccccc agccgacagc tacacttgaa attgctgtta
     1081 aaaattccat gatgatatac cagcccacaa tccaagctgg aaattcacct aatgtcgcat
     1141 agacatagct ataagcacca ccatttgctg gaattcgtga agcaaattct gcataaaaga
     1201 gtgctaatat actaatagca atagcagata gaataataga aatcgtcagc gctggtcctg
     1261 cataattagc agctcctatg cctgtaatag tgaaaattcc tgttcccacc attgatccta
     1321 ggcccaaaaa aatcaaatcc agcattttta agtgcctatt catttcagtc ttattaatag
     1381 cttgcctttt tttacgaaag attgtcatct tgtcactttc tagtcttaaa atagttctac
     1441 ttagtttatc atagttcctg acaattgtaa atttcactaa aatgacccca atatagccta
     1501 agacctatta aaaaacgagc taggaccaaa cccagctcat cttatatatc aataatgact
     1561 aattatttat tctttagctt ctgtcatttt atccttgatt tcatcatagg ataaggcatg
     1621 tacctctgct tcatcgtttt ctggatcatt tggcatttta ccagtctcgt aaatggactt
     1681 aatttgagca gcatccaacg tttcatactt aagaagtgct tcagcaatca gcttatgagt
     1741 ttcacgatga tcattaataa tgtcagcagc cttgttacga gcttcgttta ataaatcacg
     1801 aacctcatca tcaatcattt gagctgtttg ggcagaatat gatttttcag gtgacaattg
     1861 ccctggcatc atagcatgat tgccttcata ttggactggt ccaagttttt cactcatacc
     1921 atactctgtg accatagccc tagccatttg agtggcctgt tcaaagtcat ttgaagcacc
     1981 tgttgtctga gcattgaaaa taatttcttc tgcaacacga ccacccataa gccctgcaag
     2041 ctgctccttc agatcatctt tagataaaag catttgatct tcctttggaa gcgcaatcat
     2101 atagccgcct gctcggcctc gaggcacaat tgttaccttg tgcacaacac gagcattgga
     2161 taagactaaa ccaacaatag tatgacctgc ctcatggtag gcaaccattt cgcgctctct
     2221 ctgtgaaatg ctacgatcct tcttagaagg tcctgcaata acacgatcct ctgcctcatc
     2281 aatatcacta gcatcaattt tagttttatt tcgacgcgct gcaacaaggg ctgcttcgtt
     2341 tagaacattt tcaaggtctg caccgacaaa acctggagtt tgttgagcaa caaccttcag
     2401 attgacatcc tcagcaagtg gcttattttt agcgtggacg cgtaatatcg cctcacgccc
     2461 cttaacatct ggtcgaccaa caagcacctt acggtcaaaa cgacctggtc ttaacaaggc
     2521 tggatctaag acatcactac ggttggttgc agcaatgaca atgatgcttt cattaccttc
     2581 aaagccatcc atctcaataa gaagctgatt aagggtttgc tcacgctcat cgttaccacc
     2641 acccatgccg gcaccacgac gacgaccaac agcgtcaatt tcgtcaatga aaataatcgc
     2701 tcgctcagcc tttttagcat cttcaaataa agaacgcaca cgactggcac caacaccaac
     2761 aaacatctca acaaaatctg agcctgaaat gctaaagaat ggtactcccg cctctccagc
     2821 aacagccttt gcaagcaatg ttttacctgt tcctggaggt ccctccaaaa gaacaccagc
     2881 aggaatgcgc gcaccgagtg ccttgtattt cttaggattc tttagaaaat caacaacctc
     2941 taccagttct tgtttttctt cctcagcacc agccacatct gtaaatctaa cctttacatc
     3001 accctttgct tgtgatctag ccttattttt accaaaactc atggcaccac gagcaccacc
     3061 accttgattc atgatcatca tcatgaaggc tgcaaaaatc acaatcggca gaaagctcat
     3121 aagaaaggta atccaagccc cacttgagct ttcttgtttt acagtaatgt ctgttccatt
     3181 tttatctgcg acagaagtca tttcctttaa tacagaatca gatggtaaaa ttaaggccgt
     3241 aaattctgtt acctcagtgg ctgcactatt acctaaaaat gacaagcctg tgtcaataga
     3301 caccttttga ggcttttcat attttccttt aacctcaaca atgctgccac taggctgata
     3361 gctaagtgat ttaatatcac ctgccttcaa atgcttaatt aattttgaat agctaatttg
     3421 ctggctttgt gtactagttc ctcttaagta atattgaaat cctgctacaa caataacaat
     3481 catcaatata tatataaaag aatttttgac aaatccatta tttttattat ttttcataca
     3541 acaataattg accttttcct attttgaata gacttcctct tttaaaacac cgacataagg
     3601 gagatttcta taattttctg cgtaatctaa tccgaagcct acaataaact cattaggaac
     3661 attgtagcac acatagtctg cctcaatgtc taccacacga ccctctggct tgtcaaatag
     3721 tgtgataatc ttaacggaat tagccttacg atatttgaac atgtcacgca aatatttgag
     3781 tgttcgacca gtatcaataa tatcttcaac aaagatgacg tctcttccct caatattggt
     3841 gtcaacgtct tttaagattt taacctctcc actgctagtt gttccaccat tatagctaga
     3901 aacaaccata aaatcaattt caacgtgagt gtcaatgtgc ttcatcagct cggccatgaa
     3961 tggaacagaa ccctttaaga caccgaccat caagggattt ttaccatgat aatcctttgt
     4021 caactgctca ccaagctcct tggtcctttg aataatgtca ttttcagaat aaagaatttt
     4081 ttgaatatct tgctcaagca tactgtcacc ttttttctaa tttatcaata tacagtttag
     4141 ccaacattat atcatgttta gacgcttttc tcaaatatgt ttcatcacca accagcacaa
     4201 aaataataac tccagcctgt tctcctacga tggcattttg acgctgctca cttgtaaact
     4261 ttccatcgat gaataaacgt cttaattttt ttgaaaattc accaagaaaa agcctatctc
     4321 ctgcctgcct atgacgtaaa gtaactggtg ataagctata taaagggata gctatatcat
     4381 gtcccttatc agtcaaacta cctgagaaaa caaatcgata ccctctataa tttagggaat
     4441 caccgtatga taccatttta aattctcgat ttaaatcagt ctttggaatg atttttttaa
     4501 tagcaaaaga ctctttttca atgaggagac aataagtatt tttaattgga taaatcccct
     4561 gcttttgtcg tctgatgatg tgtaaaagat catcaaattg tgatttttta atggctagct
     4621 gtggaaacgt ttctaaataa tgctgaagca aaaaaaactg aacagcagct gattgagcta
     4681 aaaaacagtt taatcgatga aattcaagtc ccttggttaa atcatcaaag gcctgaagca
     4741 gcaggcgact ttccgcagat aaatcaatca aagattgagt agcttgagga ttttctcttt
     4801 tgaaatctgg caggtaatga tgacgaacac gattgcgaaa ataagccatg ctgtcattag
     4861 aatgatcttc aaaatgaaag ggattaggca gttctgcttt tgataccgtt aaaaacggtc
     4921 gtatcaactg accattagca aagggctgaa cctctctgat accagctaaa tgacgcaatc
     4981 gactaccacg aatcagtctc atcaaaatag tctcagcctg atcatcagca tgatgtgctg
     5041 tgactaaagc cgaataatgc tcctgctgca tgatctcttc aaaaaattga tagcgaagat
     5101 gacgcgcagc attctcagaa aaagcgccct gaaaataagc aacatagata ggaatagcat
     5161 gctttttagc ccaagacctc aaataagcct cttcgtcatc tgattctggt ctttgcttgt
     5221 gattgacatg cgcaatgcca atccgaattt gcaattttgc ttgaaaagca tgcaaaaagt
     5281 gcagcaaatt catcgaatct actccaccag atacagctat caaaacagcc tgatgagcgt
     5341 caaaataggc cttctttttt atgatgttat aaatgtgttg ataagtcatt ttaaaatcga
     5401 ataaacatcg tcagcaattg ctgtgatgtc gtcataggaa gccttatctg taaaaacgga
     5461 taagataaag ggattatcac cataaacaat ggcaacatca tgcttgtaat cgtaggcgtc
     5521 tccaatcttg tgagccactg gcacagaaat attttttgaa atgcgctgat catcaaatgc
     5581 cgtctgtgac aaataagaaa taatctgacc tttttgataa tagatagctt ccatgagatt
     5641 tgctgctgca tgagaagaaa gcaagcgctt ttccatgtcc caatctactc cagctaaagc
     5701 cctaatctct gattgaaagg cttgattata ttgattacat aggtagtagc ctaagatatt
     5761 agtagcaaca ttgtcagact gctgagccac agcctttaaa agctccatca cattatagtc
     5821 ctttttgtca gctgttttac tgattttacc actgccagtt ggatcgtaat caccataaaa
     5881 atgattgacc tcatcaatgt attttaagct cttaccttca gataagctac ctgacttcag
     5941 ttttttttga acactgtaca gggttgctaa tttggaaata cttgccgcat acatctgttt
     6001 atcagcattg atacctgcac tggcctgcgt gttaagctgc tttacaaaaa tagaataatt
     6061 ctctttatta tatttttgca atagcatttc ctgaaccttc aacatgcgat tgtcggtagg
     6121 tgacaactcc ttttgattaa cccagccctt atgatcaatg aaataatagg tcccatgctc
     6181 tgtttgagcc atcttactag catgaacctt tctgccaggc tcactatctg atgcaattgt
     6241 cttaacacct aaaacatagg gttcagcata tatagtcatc tttttttgag tccaaaaatc
     6301 caaatccaca gctgtctgct caaacataat atcctcgtaa acaatctgac gactagcttc
     6361 aaggtaagtg tcatctgcca gtctaaagac aggaatagct gccttgttta gcaaaacatc
     6421 cttgataaca attctattgt ctggtgcgat catcgtcttt ggcacactca attcgggatc
     6481 cctataagca actgtctcct caaaaacatt gggattagtc ggaatccgac tataataaag
     6541 agtggagcta acaatatcct gacttaagtg atagcgtgtc gcttcagaaa acactgggat
     6601 tttttctgta ctaatgaccg ttaaaggagt cacgaaaaat gtcattaaca tagctgctaa
     6661 taattttttc acaatggctc cttcctattt tacttctgtg cgatgatggt ctttcttcag
     6721 ctcttgattt tccttttcta gctctgctaa tttgtcatca gaaaaggcaa gaaaggtttc
     6781 aattttttcg acaatattat ccatagtcaa ttactatttt ggtaataatc caggagttgg
     6841 ataaataacc tctccttctc ttgataagta atatttagcc ctagcatact ttttgacaaa
     6901 atcatcattt tttagctgct cagctaactg cttttcagac ttagtctttt tttctaactc
     6961 acgatactct ttttccaacg taataatctg ctgaccttgt tttttcagtg aaacataacc
     7021 cttaaccaag ttataggttg gcagaataaa caagaacatc atactaacca agatccaacc
     7081 cataaaacgg ttccgttttt ggatttcctc ttcctcaaac cgttttttga tattttcttc
     7141 gttgatataa tggttattca actggacgat actaggcttc ttcatcgcta cttatccttg
     7201 tttcgctgat aatgtcatac attttagcag cgtcctcttt tttagtgcta tccttcatat
     7261 caagcacacg aacagtaagc aacttattgc caaacctgat ttcaacctga tcatttagtt
     7321 ttaaatcagt tgagcttttc gcaaggatac cattaacctt aatacgtccc ttatctgcga
     7381 cttctttggc cactgatcga cgcttaatca atcttgatac ctttaaatat ttatctaatc
     7441 tcatatcttt tgcctcacaa tccctttcat tctatcattt ttctttgaca aatggtagaa
     7501 aagaccacaa tttctcttta aagacaccta gctttttgca agctattaaa aaagaggata
     7561 aaccaacagc agatgacacc aaaagactaa tcagcgcacc aagtcgacct gataatggca
     7621 agcaatactg acttgtaagc acacacatga gcatgatcac taaagcaagc ccatatttag
     7681 cattcactat cgctttaaaa tcaatatcag ccagcacagc atacaagagt aaaacgacca
     7741 gcaaggggat tagggtggat aaggagcttc caacaatagc gtaatagtag gttaatatag
     7801 gtgttaagcc taattttaat aaaaagccaa acagcaaaat aagcaaagat tgcttgatgt
     7861 gatcctcaat gaagcatttt tgatgaaaga attgaatcat gcttgatact gctataatca
     7921 tcaggtaaac cactaaggcc agccagccct tattgtcctc aaataaggct cgattcatca
     7981 gatggagaat actaataaaa ccaacagtca gtgttaaact aaaataaaag ataaactcaa
     8041 agaaacattg actttgctct ctataggact cccttttaat atgaaacaag actgttaaat
     8101 tcggtaaata agctgtaaat aaggccgtcg aaaaaatgag accaaattgc agcaagggct
     8161 gtcccctatc gtaaacaccc ttagtcattt cagctgttat ctctgataag cctgagctaa
     8221 ccaaaatatt tttcaccaaa agagaatcta tcaattgaaa aacaagcagg taaattgaaa
     8281 aaagtaaaaa aactaaggtc ggcaagccca gacttgttaa atctctaata gcaaccgtat
     8341 ctcctgataa aaagcttttt aatgaataag cactatgacg cttcaaataa gctaaaataa
     8401 ctaagctcgc tactaaattt ccaaaagcag caacatttgc tgttaaataa accgtccaac
     8461 caagcaccct gtagcatagt gcagcaacaa tgattatagc aactcttatg atctgctcaa
     8521 gaacctgact cagagctgta ggagccatat tcatatcagc ctgggctaag cctctgtaaa
     8581 aggatataaa gggtactatt aacaaaacca ttgctgttat aacaattgat ggtgccaact
     8641 gctgtgctcc catccagcta gccaatgcct tatgacttag caccaatatt cctgacaata
     8701 agaagctggt atagcattgc aacttaaata gagctgctag ctgtagctgc ttttttttct
     8761 gggccatact ggcaatcaca ttgggtaaag cagttagacc taaggctgaa ataataccta
     8821 gcaaaggata gatttgttgg taagcataaa agcccctatc ccctaccaaa ttttgataag
     8881 ggatacggta actggctgct aataattttg acataaaacc actaataaca atcagaagac
     8941 ttgattgctt agttttatga ggaagctttt ctagatttaa tctcaccaag tgtctctcca
     9001 aaaagtatca attcttctaa aatgacatgg tctttctgac gtctaacatc aaagataatt
     9061 tcaattttac cctgatgctc actaatcctt gcttttaagc ttgtttttga cagagcctca
     9121 aaataatcct gtgtcaaata gtattgaagc gaagcaacct caaacctaac cataacctga
     9181 tggtccctct tctcgactaa ttcagcaaag gctgtatcca agtagtattt caacaagcca
     9241 atctccagta aataggctac ctgatcagga tagtcaccaa aacgatccat gatttcatct
     9301 tgcaaatcag aataagctgc tctagagtca atctcacgaa tgcgcttata aatgtcaatt
     9361 ttttgacgct cgtctttgat ataatcacta ggtaaataag catcaatatg cagattaatc
     9421 tctgcattac ctttttgtcg cgtcaatgct cttccttgct tgcttgcaat agcctgctcc
     9481 agcagctgag aatacatgtc aaaaccaact gagtcaataa aaccactttg tgaagcaccc
     9541 aatatatttc ctgctccccg aatagataaa tctcgcatag caattttaaa gccagatccc
     9601 agctctgtaa agcccttaat agcttctaac cttttttcgg aaacctctgt tagtacctta
     9661 tcaggcttat acatgagata agcataggca atacgattgc tccttccaac acgacctcga
     9721 agctgataca aagttgatag tcccatatga tcagcatttt caataaataa ggtattgaca
     9781 ttagaaatat caacccctgt ctcaataata gttgttgcaa ctaaaacatc ataatcacca
     9841 ttgataaaat ccatcaaggt attctcaagc tgaatgtcac tcatttgacc atggacaaaa
     9901 ccaatagaag cctctggaac caattcttgc agctctgcca ccttcttgtc aacagtgtca
     9961 accttattgt aaacataaaa gacttgacca ccacgatcca tttctcgaat aatagcttcc
    10021 ctaatcaagc caggattatt ttctaaaaca taagtctgaa caggatagcg attcgtagga
    10081 ggcgtctcaa tcactgataa atcccgaata ccaagcatag acatatgcag ggtacgagga
    10141 ataggcgttg cagtcagtgt aaggacatca accttggtct ttaattcctt tagggtttct
    10201 ttatgcttaa caccaaaacg ctgctcttca tcaatgacaa tcaagcctaa atctgaaaaa
    10261 atcacatcct ttgacagcaa cctatgagtc ccaataataa tatcaacctg accctttttt
    10321 agcctttcta gactttcaga ttgctctttt ttactgcgaa agcggcttaa aacagcaatt
    10381 tcaaccggat agttctcaaa tctttcccta aaattctcat aatgctgctg tgctaaaacg
    10441 gttgttggta ctaagatagc tacctgctta tggtcaccga tagccttaaa agcagctctc
    10501 atagccacct cagtcttacc aaagccaaca tcaccaacta gtaaacgatc cataggtctg
    10561 acactctcca tgtctttttt aacctctttt atggacctaa cttgatcatc agtctcaaca
    10621 aaggcaaaat cctcctcaaa tgctctttgt aactcatcat ctggagaaaa ctgaaatcct
    10681 ttttgctgac tccgctctgc ataaagcttc aacaggtcat ctgcaatatc ctcaacttgc
    10741 tttttaaccc tttgctttgc tttttgaaaa cgaccatcgt ttagtttatt aatctttggc
    10801 tctttaccat ctgctgatac atattttgat aagctttcaa gctgatcaac aggcaaagaa
    10861 attcgatctg actgctgata ctgaatggtg acataatctc gatgtacccc ttgtatgtta
    10921 atcgtttcaa tgcctaaaaa acgaccaatc ccatgcacac tgtggaccac ataatcaccc
    10981 ttagacaatt cattgtaatc ctttaagcgt tcagcattac tcatattagt acgacgagca
    11041 cgacgcttca gcctcttatg atatatctca tgctcagtaa ttaaaactaa tttttcatca
    11101 gcaaagtaaa acccacctgc taggtgacca ataatgattt gtgcttgatg taatactatt
    11161 gcatcagcag aaacaagggg caattgacat tgataagcct caagagattt tgccaaccgc
    11221 tcataagctt gatgagattc aacctgtaaa aggacagttg ctccagattt ttgataccgc
    11281 ttaatctcat caatgagcag tggaaattga ttgaaaaatt cctgcatggc atactgtgtt
    11341 aagctataca ccttatcaaa tttaatatta ccaagtccct tgtgaaaatt tgaaaagaag
    11401 gtggcaggct tatagtgtcg cagctcacga taattgtcag caaaataatg gagaaatgga
    11461 agtgactttc cttgctgtaa atcatctgtc aacaaatgag caagctctaa gtcaaattta
    11521 gcatttctgt caactaactt ttggaaatca tcaaaaaata ctggtgttcc cttaggaagg
    11581 taatctagaa tcgtccattc attatcataa aacagtgatt gaaatttacg gatgtcctta
    11641 tgcttcaggc cttcttttgt tacagtgagc aactcctcca gatagccttt atgttctgcc
    11701 ttagcaagtt gaagctgctt ttcaagatta tgactagccc tatcaaaatc ctccggctca
    11761 aaaatcatat cacttgcagg cttgatactg gtgctatcct tcttttggag agatttttga
    11821 ctttctatat caaagctcct aataccatca atctcatcac caaaaaattc gatgcgaaca
    11881 ggtaagtcct gtgttacctc gtaaacatct aaaatatcac ctcgtctgct aaattcacca
    11941 ggactaagga cctgagccac cctttgataa ccaattttga caagcttctt gacaacgttg
    12001 tcaagatcag tgtcaactcc tactgctaag tcaatctgcc cctgctgaaa agtcttagga
    12061 cttggaagta ggattctgag tcctgctaag ctaatgacca atattcctct tgcttctgga
    12121 tttgataaaa aagctagtgc ctctattctc gagattgttt tatccataga ggagaaaata
    12181 aactcagccg cagcagtatc atctgcaaaa aattgaaaaa tagagccctc atcaagcaag
    12241 gctgacaaat caccagctaa tttttccatg tcattttgag ttgatgtcac cacgaccagc
    12301 ttcccttgaa agctaagata ggctgaggca atggctgctg ctttacttga gcctgacaag
    12361 cccatgacta attgccgttt taagcttgtt acatcacatt gccaggtctg gattgacttg
    12421 ttttgattaa ataattctaa aatatccata actacccatt aaattgctgc attgttttct
    12481 caatgctttt ttcctgtaaa taatagttga ttgctttgtc aaccttatca agtgctatat
    12541 tgattgttat catatcatct gtatcaaatt ttcctagaac atgattaata acactcattc
    12601 catgacttgg tcttccaata ccaattttaa ccctatcaaa ttcctgtgta ccgatatgag
    12661 caataatgga ttttatacca ttatgtcccc ctgcagagcc tttttgacgc aaacgaattt
    12721 taccaactgc catatctaaa tcatcataga tgaccattaa atctttagtt gaaatattgt
    12781 aataggtcaa taaagcccta acagcaagac cactattatt cataaaggta gttggcttaa
    12841 caaaataaat cttttcttga ttgataaaag tactcccaat aagggctttg aaggttttat
    12901 cttctgtaaa gctaacgtca agatccttga caagtctgtc aactgccata aaaccaacat
    12961 tatgctttgt ttgctgatgt tttgagcctg gatttcctaa tcctacaatc atttttacca
    13021 tactaataca ccagagaaac gaggtatgat agcagcctgt tgaccattct taaagcttta
    13081 tcagcctctt cccctctatt ttttgtcctt tctaagcttt tgataggcac caaaagggct
    13141 ggaatactat cccaacccta gaacacaata ttgttaccac taaacattga atctaaattc
    13201 cataatatcg ccatcctgaa cgatatattc ctttccttcc tcacgcagac gacctgcctc
    13261 tttaacagcc ttttctgagc catacttaat caaatcatca tagctcatcg tcaccgcacg
    13321 aataaaaccg cgctcaaaat ctgagtgaat gataccagct gcttgtggtg ccttaatacc
    13381 gcgcttgaag gtccatgcac gcacttcctt ttcaccagct gtaaagtagg tgccaagtcc
    13441 aagtaaatga taggctgcac gtgtcagctt gtcaacgcca gattctgtca gaccgatagc
    13501 ttctaaaaat tcactcctgt cttcatcatc taactctgaa atctcttctt ctgcacgagc
    13561 tgaaatcaca acaacctctg cattttcagt tgctgcaaag tcacgaatct gcttcacata
    13621 atcaatagcg tctggaattg ctaccttatc ctcatcaacg tttgccacat aaagcactgg
    13681 cttagtcgtt aataaaaata actgcctaac aattttttgc tcatcatctg taaagctaat
    13741 ggtacgagca gatttgcctt cttcaagcac tggcttaatt ttttcaagga cagcaaattc
    13801 tgctacagaa tccttgtcct tttgtgtacg ggccattttt tcgacacgcg catagcgttt
    13861 attgattgat tctaagtcag ccaaaattaa ttcaaggtta atcgtatcaa tatctgccaa
    13921 aggatccaca aaggcatcct cacgcccctg ctcacgcatg acattttcat catcaaaggc
    13981 acgaaccaca tgaacaatag catcaacctc gcggatattg gctaagaact tatttccaag
    14041 tccttctcct tttgaagctc cctttacaat acctgcgata tctgtaaatt caaaggttgt
    14101 aggtactgtt tttttaggcg tgataagctc tgtcaacttc tgtaaacgct catctggaac
    14161 ctctaccata ccaacattag gatcaattgt cgcaaaagga taattagcag cctctgcccc
    14221 tgcttttgta attgcgttaa ataaggttga tttcccaacg tttggcaaac caacgatgcc
    14281 tgctgttaaa gccatatttt tttcggtctc cgttacattt tttcaatcct tatcattata
    14341 gcaaaaaaaa gaagaaaaag cttgcctagt aatgatcttt aactaaaatg gatcacaata
    14401 aaatacacac ctaacaaaac gatcacaacc aataatagca taagaagatc gcctttacgc
    14461 attggccgct tagattcctc agttaaaaat tcccatacgt tcattggctt ttcagttttc
    14521 ttaataacct tgattgcagg ttcttttcca gtcaccaatt catctaaagt tacctctaaa
    14581 acagctgcca atgtaactaa attttccaaa tccggtgtcg catctccatt ttcccacttt
    14641 gaaatagcct gacgggagat gaaaagcttc tcagctaagg catcctgaga caactgcttt
    14701 tcaagccgat acttctttaa ttgttctgca aatttagtca tcattaatga ccgcctttcc
    14761 tttttgatag ctttacaata actctttttt aaaaggcaag ctagcaattt ttaacgcaat
    14821 aatgagttgc gaaggtagtt aaaaacctta tgacaataga gcttctatgg ttgcagaacc
    14881 ttcttcattt tacgctcaaa atcatgacga cttagcatga taacatgatt acagttagtg
    14941 cattgcagct taatatctgc tcctactctt gtgattttcc attgatttgc cttttttcct
    15001 gtttctttaa tgacacaggc atggggcttt ttcatttcaa ttaaggatcc aacttgatac
    15061 atcactttat cactcactca tctcttatat ttattattta tcataacaaa aaaagccccc
    15121 aaaagggagc gtttttcgct tagtttgtac gaactggtgt gattaattga ataaagctct
    15181 cttcatcatc tcccggtgtt aaggtgaaag gacgaacagg cgataggaag tgaatcttaa
    15241 ccgtctcact tttaatggct tttaaggctt caatcagata ggttgggtta aagctaatgg
    15301 ttaaatcatt ccctgcttga ctcaccacgt ccagatcctc gttaacctta ccaacctctg
    15361 gagagttaac atgagctgaa atgcgatttg cttcaatttc aagcttaaca gtaccatttt
    15421 gcgtagcgtt tgaaatcaag aaagcacgct ccatagcatg tcgtaaggat tgtgtgttaa
    15481 aaacagcctc tgtctcaaac tgcttcatca gcaaacgatc agtatcaggg taattacctt
    15541 ctaacagacg ggtgtaaaaa gaaatgtagt cacttctaaa tagcatttga ctagcagaaa
    15601 agaacacttc aacggtttct atatcatctg taaagacagc tgaaaattct ctcaaggatt
    15661 tacttggaat aaccacatca aaatcagctg aggttttctc cagagtaatc aagcgctggc
    15721 tcatacgatg tgaatctgtt gccaccgctt taaagttctt atgctgactt agggtgatgt
    15781 gtacgcctgt caaaatagga cgactttcct gcatactagc agcaaaggct gtctcagcaa
    15841 tgatagattt taagagtctt gtatttaaaa ttaaaggatt ttcagttgat acctcttgaa
    15901 gacgtgggta ttgagaaaca tccttcccct ttaaggtgat ttcagatttc ccactggtta
    15961 gcaccacctg atgctgttca atttccttaa attctaagct aacatctgga agacttgaga
    16021 taatattgat aaaaaagctg gcttctaaaa gaacagcccc tgttgaggtt atcaacaagc
    16081 ctgcgttttc attgctaaca ggaatggtat tttcaataga gatttgacca ttagagccag
    16141 tcagggtaat gtctgatgga ttaacctcaa tcttgatggt tgataagatc ggtatagcat
    16201 ttttactgct gatagccctt ttagtggctg ttaaagcttg aatgaaaagg gctctattga
    16261 tagaaaattg aatcatggta actcctttgt tatataagta ttatagctag tagtagtagt
    16321 aggtcttgtt aaaatagtgg ataagtctcc ttgtactagt cgttactagt taaaacgctt
    16381 gtgcacaagc tgtggataaa ttttcctttt tgctaaaggt tatccacatt gcttatttga
    16441 ttttgttctt gatggtttca atttcaattc tgaggctctc gtcttgtcca atcatgtttt
    16501 taattttgtt ataagcatga agcacagttg aatgatcacg tcctccaaat tctttaccga
    16561 tctttggcag actgttatcg gtcatctcac gagctaaaaa catagcaacc tgtctagcaa
    16621 gcacgatatc ctgtgtgcgt ttggtcgcct tgatttcctt aaccgtaacc ccataaaatt
    16681 ttccaacctg agcttggatt tcttcaattg gaatgacagt catcttagga ccgtcttgct
    16741 ttctagctcg aatagcttct gctgctatgt ctactgtaat tgtatcaatt tgtttaaaat
    16801 tagccacaag actaatatcc ttcaaagccc cttccaggtc tctgacatta gagtcaaatt
    16861 gaccggccaa atattcgatg gtgtcctgag gaaagatgaa attatattct tgaattttat
    16921 tggtcaaaat agcaacacgt gtctcaaaat caggcggtgt gatattaact gttagtcccc
    16981 acttaaatcg agttactagg cgatcttcta ggtcattgag gtgatcaggg gttcggtcac
    17041 ttgttaaaac aatttgcttg ttattgttat gtagagcatt gaaggtgtta aagaactcct
    17101 cttgtgtacc agacaaggtt tttttagcta gggattgaat gtcatcaatt aggaggagat
    17161 caagattgcg aaatttctcc tttagctcgt ccatagtatc tagacgaata tgaacaacaa
    17221 attcattaat aaaattttca gccgtaatgt atttaatcct agcatttgga ttttccagta
    17281 aaactgaatt tccaatagca tttaaaagat gggtcttacc aagacctgga cctccccaga
    17341 taaataaagg attataggtt gttcctggtg tattagctac cgctattgat gcagcaacag
    17401 cccacctatt ttcatcacct tggataaagt tgtcaaagct gtatttaggg tttagatcgg
    17461 actgtactgc tggtaattgc tggaaggctt gttcagtata tccttgctgt ccctgatgct
    17521 gttgctcaat catcaagtca tcctcataga catagtctac agcaatttga gcattgtaaa
    17581 cttcaaatcc tgctgttagg ataacgtctt tgagattttt ttcccaaaac aattccttca
    17641 tctgatctaa aaaaattgtt gcgacatgat tgtctacctt gatcaaacga gcatcatgaa
    17701 caaaaaattc ataagttgcc tgctttaact ggctttgagc tagctctaag accctattcc
    17761 aaaaaatttg ttcattttca gtcatacgag attccttctt gtggataatt ctagaaccat
    17821 tctatcataa ataaagatag ttttccacaa aggatcaagg attattttag acttacccac
    17881 aagctgtgga gataaaatac acaatgtgta agatagtttt ccacaacttg tggaaaaaag
    17941 agaaagcctt gtgataaaag gttttagccc catttctctt gtggaaaact gaataaaaaa
    18001 aacagacaat caacaagcta aagcaacttg ttgataattc tgttcaattc ttcttggttt
    18061 gaaaatgaca gttgcagctg cccactgtca tttttttgga gagacaatgc cacaggtaat
    18121 cctaatgatt ttgagagctc tttttctaaa gacttcacaa aaatggtttt atgtttgttt
    18181 cttttttttg ggggatgctt agtctttacc agctgttcga tttgcctaac gcttaagcct
    18241 tgatccagaa tgttgtgaaa ataaagctcc tgctcttttg gtgttgacaa ggataataaa
    18301 gctcttgcat ggccggcgct aatggtaccg tcctcaatcg cttgtctaat aacgtctggt
    18361 aattgcagca gtctgatggt gttgctgata taagggcgtg attttcccat gtatgtcgcg
    18421 atgtcctcat gggtcatctt atttttatca ataagtaatt gataggcctt agcctcttca
    18481 atagcattta aatttgagcg ctgtaggttt tctacgatgg cctgctgcat gctctcaaga
    18541 gtagagattt ccttaacaat tgctggaatc ttttgaagtc ctgccagctt ggctgcttta
    18601 aagcgtcgtt ctccagcgac taattcatag ccaaatacat cagattttct gacaatgatt
    18661 ggttgaatca aaccattagc ctgaatggaa tgtgccagct cttcaagctc tttttgatta
    18721 aattgaagac gtggttgata aggatttgcc acaatatcct cgataggaat gtgcattagg
    18781 atttctgtca tataagcctc tcaaaaggga aatagtggta gcttaacggt tattagagat
    18841 acatacggga taaaagagca agagcccgcg accatcgtct cggactcaat ctcacgggga
    18901 tacccaatgt ttactgcttt ttagttagat ccttagttgt ttttgttaat ttgatgtcaa
    18961 ctttcttctt agcagttcct ctgtagaagg ttaccttaat ggtgtcgtta atctcatgac
    19021 tatataagac actttgtagg tcactaattg agctgacttc tttaccgtca acctcagtaa
    19081 tgacatcata ctgctccaat ttaccaagag caggcatgcc atcttgagta gaggctacga
    19141 caacaccgct ggtaacgctt gttggaatat tcaattgaat caatgcattg gttgatagat
    19201 tacttaagtt taccattgta atgcctaagg ctggtctgat aacagctccg ttagactcta
    19261 gttggttaat aatggtgaca acatcgcttg atggaatagc aaagccaatt ccctcaatgg
    19321 ctccgccgct accagtaggt gttgaggata ttttacttga gttgatacca ataacctggc
    19381 cttcaatatt gatgagtggt ccacctgaat tacctggatt gatagcagca tcagtttgga
    19441 tagcatttgt tgagatggtc tcgcctgcct catttcttga agtgactgta cggcttagac
    19501 ttgaaacaat cccttctgtc actgagttgg catattttgt tccaagagga ctaccaattg
    19561 caatggctac ctctccaaca ttaattttgg ttgaatctgc aaatttggct attgttttga
    19621 ttttatcagc agcaactttg acaacagcta ggtcagaata agtgtctgca ccaactagtt
    19681 ctccaacgat cttagagccg tctgctgtta aaatttcaat tcgttgagct ccctcaataa
    19741 catgattgtt ggttacaaga taagcagtat taccttcttt tttgtagaca acacccgaac
    19801 cttcactgtg tatgcttagc tcgtcctctt tttgtactgc tgaggtatca ttttcttctc
    19861 cgaaaagatt gatgtaagga tttgaaatgg caggcgaagc agccttttga tagttaataa
    19921 cagacactac agcatcttga accaccttaa cagcctttgt tgtatcagtt gtattattaa
    19981 agctgacgtt gcttgttgtc gttgctccct ttgcatttga agatgttaga gaattctgac
    20041 taaatccatt aacaactaag gcagctaata agccccctaa aaatccaatg gctaaaaccc
    20101 ataagggctt caatatattt tttgatttta acacaaaatc acctccgaat ggttttcaca
    20161 taggatataa aacctcactt aattatacct taaaaccata aaaaagaaaa gtaatccaca
    20221 acttgtggaa aacttttcag gactatacta aaaaggctgt agaaaagggt ttatataaag
    20281 aaaataagaa atcaacatgt ggataagttg tgtaaaaaga gttgattatg gtacaataag
    20341 gatatgaaaa taaagcttat ttgtgtcgga aaattaaaag aagcgtattt aagagatggg
    20401 attgcagaat accaaaaaag actgtctcgc ttttgccaat gtgatatcat tgaattagca
    20461 gatgaaaaaa cacctgataa ggctagccat gctgaaaaac agcagattat ggctaaggag
    20521 gctgacagga tcaagaaaaa gcttggtcag cgtgattttg taattgcttt ggcaatagag
    20581 ggcaagcaat tggcatcaga acagtttagt catctactat cagaggtcac tgtaaaaggc
    20641 tattcagaca ttgcctttgt cattggtggg agtcttggtt tggatcaatc cattaaaaat
    20701 agggctaatt tattgatgag ctttggccta ttgaccttac ctcatcaatt gatgcgtttg
    20761 gttttaatcg agcaggttta tcgtgctttt atgattcaac aaggcagtcc atatcataaa
    20821 tagcagttgt ttcacatgaa acactacaca tggcatagaa gaagcgcgtg tatacctcaa
    20881 ccatacttct agctttcatt aatagggctg ttgatttgca gccttactca gctattgcct
    20941 gatgataaaa gcattaattg ctttatcgaa ctgatgattt ggaggttttg tgattttagc
    21001 cttagacgat gtcaggcaaa tgcttatcac tcttatgact ctcctacggg agtcagtagc
    21061 ttactattgt tagaaataca aaaagccatt agatactgac taatggcttt ttttactatt
    21121 tctgatctca gcaggattcg aacctgcgac cgttcgctta gaaggcgaat gctctatcca
    21181 gctgagctat gagacctcaa ccaccttatt ttaacaaaaa aaccttatgc ctgtcaatgc
    21241 ttatttttga taagaagctt cactgcccta aacgtgcggt gatatgtctt ttagcagttt
    21301 gtatcagagg agcaatgtgt tatgttttct agcatgtttg gggtaattag acttgtttta
    21361 gactgtttat gtcaaaagtg atcaaaaaat caagattttt ttgaaaaaag tatagacaaa
    21421 taaaaacatt ctgctataat aataagagtg ttaaggagag ttactcctga acttcaggtc
    21481 cgttggtcaa ggggttaaga caccgccttt tcacggcggt aacacgggtt cgaatcccgt
    21541 acggactatc agaattgtct ttgtggcaat ttttttattt tccggcatag ctcagttggt
    21601 agtagcgcat gactgttaat catgatgtcg taggttcgag tcctactgcc ggagtgataa
    21661 gacacttcct aaggctttct taggattttt ttattgacct tgaagagtga ttgtgatttg
    21721 ctaagaaact taaaaatacg ctaatcgtct aaatgatagg cttctctttt ttgggactaa
    21781 ggaacacgtg agttatggaa agtcatgtgt tttgataaat atccttaaat caatagacca
    21841 gctaaaaaca cttgattttg atacctggaa gggctgtaaa atcaagcgtt ttgcttatat
    21901 atggaaattg ctgtttaagc ttttagcttg gctgtttgcc tgagtaagta gtaatgtaag
    21961 aagctgtaaa gcaagatacc aataaatgag agcagtaagc ctaatgtaaa gccatttgga
    22021 acaaaggtga gtactaattt accagatcct tttggaacat ctatcctaat aaaaccacct
    22081 tgagcctttt taagagccac tggtcggcca tttagtcttg ctgtccagcc tttgtcatag
    22141 ggaagggtaa aaatcataga gccttctgat ttggccttgt aatggctaat gacctgattg
    22201 ctacgggtgt aagtagtaac ctctttttgg ttaatcgcat tcatggctgc cagatagttg
    22261 tcactattta aactgtagaa gtgtggggta gcaaaggaaa tatttttgtt tttcggaaac
    22321 ataatagcaa gggttaaggt tcttcctttt tcaaagtacc ctaagtcaaa gaatgaaaaa
    22381 gcgttgtcag tagtgtactc gtaggtctga tcatcaatac ggatcctaac agctgttgca
    22441 ttgtgatttg aaaagctaat atttggaaga cttaagtaga gctgcctatg gtttggtaca
    22501 gtaacctgat aatgaacaat ggttgttgac gtattctcag cagcctcccc tgaaattctc
    22561 ccattaaata cctgagcatt tgatattagc ttagaaggct ctagctgaaa ataggtgagc
    22621 ctttttccac tcagctgatt cagcagcttg gtttgattgt caagtgtgtt gacagttaac
    22681 ttgacatctt tgtaaatgtt atctgttaag atagctagat tgctgctata gtgattttga
    22741 tagagtgtag tgtgatgact ggaggctatc cttgaaaagc caaatttatg aagctgatgg
    22801 tagctaagat tgtattttat ccctaaaaga ctatccatga tgagagtgtt gttttgatag
    22861 cgaaggttta gatttgttcc agcagactgg tagcctagac gatccagaag ggagctggag
    22921 tgacgatttc ggatagatga aaattgagaa atgccattat agctgtattt catactatca
    22981 ttgcctgttt gtggtaggag ctgctccagt ctgaaaaact gatcattgct atcagctgtt
    23041 ttcttgacaa gtctgtcaat atcctgtaaa gctctactat agcccttacg tgatggaaac
    23101 acccattcat gatgaatgcc attaagctga taataggtat ttaaactggt ttctaaacag
    23161 ctaaacagta gggtaaaaaa gattaaaaat ggcattggta cagaggtttt ttgcatgctt
    23221 aacaataaaa taagatatgc cgctaaaaag gcaagactta agatcaataa actaggctgt
    23281 aaaaagctat actgatccat tgtcagataa ggaagtgtta ataagcagct taataatata
    23341 aaggcaaaga ttattctagt gttagtaatg tctttttgtc tagaaagggc ttcgcaggct
    23401 aaaataatga taatgattga aaatgaccac gaatagcggt gcaaaaacat attgggtcca
    23461 tgcatgccct gccaaaataa atctaagggc tgaagataaa agctagccat gatgagtcct
    23521 aaaagcagcc catagcccag tcttaagcgc cagctaatag attttaaggt gaaaaagacg
    23581 atacttaaca atgaaggcaa cagaccaata aatatcatgg gaatcgcatt aaactttgtc
    23641 gtatcatagg caccaagtga tagctttgct aataaatcaa aggctcctat aggcttaatg
    23701 ataatctgat tgattggaga gagtgtttca ccgtaggctg ttaggtctag ataggccggt
    23761 atgagtataa aagcacttgt taaggctgat aagattgaca ctgatgtaaa gcttaaacag
    23821 gctcttaacc gtcttttcca tgtgtctagt gatataaggt tgactagaaa taataaaaaa
    23881 ataaagatag caaccatata tccaaaataa taatgctgga taaagagaag actaagtgag
    23941 ctataataaa gcaagggctt ggtttgagta atcagccgat agagccccag taagacaatt
    24001 ggtagaagaa taaaaacatc taaccagttg ttaagctcta gctggcttgt cagaaagctc
    24061 attagggagt aagagactga taatgtcagg actaaaaagg gtttgatttt agggtaaata
    24121 cgatgaaagg agaaataagc ggcaagcccg atcaaaccaa atttaataag tgtcaagaga
    24181 tagatagcat ctggcatgga ttgcagatta aaaaaataga caagaggaga caaaaggctg
    24241 cctagataat agctagccag agcaaaaaag tttacaccta ggccactggt aaaggtgtaa
    24301 aaaatactat cagccccatg aagaatattt cttagggctt gcgcaaaaat aacatattga
    24361 tgaaagccat cactagctaa aatggttttc tcactgccat atgaaattcc cattgacaaa
    24421 agaacaaaaa acattatcaa aaagggaagg aggaagctag caatgtcata aacaagagac
    24481 catgctttag gttttgtcat aaataagccc ttctatgata tttttgaaaa aagagctaga
    24541 aatagtttcc agccctcaga tgtcatcggt gatcatctct atactttaat gatgatattg
    24601 agcaaagctc cttgtttctt ccttatttcc aaagctctgc taccttagct tgaacgtctt
    24661 tgttttcaag gaattcatca taggtttcgt caatacggtc aatcacacca tttttagaaa
    24721 taacaacaat gtgattagca atggtttgga taaactcgtg gtcgtgactg gtaaaaataa
    24781 cagactcttt aaaatcttta atcccgtcat tgagacttga aatagattcc aaatctaggt
    24841 gattggttgg gtcatcaaga aggagaacat ttgattttaa aagcattaac tttgatagca
    24901 tcacgcgcac cttctcacca ccagagagaa cgttaacgga ttttttaacc tcatctccag
    24961 aaaagagcat acgtcctaag aaaccacgca agaaggtatc atcatcttca ccctttgctg
    25021 caaattggcg gagccattca aggatagact catcgctagc aaagtcacgt gagttgtcct
    25081 ttggcagata ggagcgacta gttgttactc cccatttgat agtcccttca tagtcaatgt
    25141 catcagccag agcgcgcata agagctgttg tttgaatgtc attttgtccg ataatggcag
    25201 tcttatcacc tggccttaga atgaagctaa tgttatctag aattttgtca ccatcaacgg
    25261 ttacagacaa attttcaact gttacaaagt cattgcccat ttcacgctca gctttaaaat
    25321 tgatgaatgg gtatttacgg ctagatggaa taatctcttc tagctcaatt ttgtccagca
    25381 ttttcttacg agaggttgct tgctttgatt tagaagcatt ggcagaaaag cgtgctacaa
    25441 attcttgcag ctctttgatt ttttcttcgg ccttagcatt acgatctgcc tgaaggcgtg
    25501 cagctaattc agatgattgc ttccagaaat cgtagttacc gacaaaaagc ttaatctttc
    25561 caaaatcaag gtcggccatg tgagtacata ccttgttcaa aaagtgacgg tcatgtgaca
    25621 ccacaataac agtattttca aagtcaatca agaagtcttc taaccatgaa atagactgaa
    25681 tatcaagacc gttggttggc tcgtctagca gcaaaacatc aggcttgcca aaaagtgctt
    25741 tagctaggag aaccttcacc ttatcaccat tggtgagctc gctcatgctt tgataatgca
    25801 attcctcagg gatatttagg ttttgtagta attgagaggc ctcactttca gcctcccagc
    25861 cgcctagctc agcaaagctt ccttctaatt cggcagcgcg aacaccatct tcctcagaaa
    25921 aatcaggctt catgtaaata gcatcctttt ccttcatgat actgtaaagc tgttcatttc
    25981 ccatgataac cacatcaatg gcacgttcct cttcgtaatc aaaatgattt tggcgaagga
    26041 cagaaagacg ctcatctggt cctaaagaga tatgacctgt tgttggttcg atatcacctg
    26101 cgagaatttt taggaaggtt gattttccgg caccattggc accaattaag ccataagtgt
    26161 tgccagctgt aaatttgata ttaacatcgt caaaaagttt tcgatcacta aagcgcagtg
    26221 atacgtcaga aactgttagc aatttgtcac ctcattttat ttatctaatc ctcattgtac
    26281 ctaaaaaagc cccttttttc aatcagaaaa gggcttaggg cttacatagg cagcagcaca
    26341 tctttgtcct ctagtttgta atgcttggtt aagctgaagc cacgtcccat gacctgtgct
    26401 gctggcatga caacgataaa ggcagtgtca tcgatttcta gaattttttc ctgtaaagct
    26461 ggcaactcat agccagaaac aatggccatt agcatgatct tgtctgatgt tgtgtagcct
    26521 cctcggatag gaatcttaga gacaccacga tccataacac ctgtaatata agccttgatg
    26581 gcctgatatt cctttgaaat aatcatgaca ttcttagaag agtcaaagcc attttccatg
    26641 acactaatga catagccaat aacgagcagt ccgatcgtag aatacatgac atcatcagca
    26701 gataaagcga tgaatcccat taaaacacta atgccatcca caatagtcat agcaactccc
    26761 aatgataatg gagaatattt gtgtaggatt tgtgtcagaa taccagtacc tccggttgat
    26821 gaatttcccc aaaagaccat tccaaggccg atcccacaaa tgatgccacc aaaaatagct
    26881 gctaataatt ggttatgagt gagtgttgga agctggctgg ttaggcgtat agcaataggg
    26941 taaatccatg aaccgtagag ggttttgatg agattttgtt taccaagaaa gaagtagcat
    27001 aaaatcaata aagggatatt gcttagcatt aaaaagagcg aggggctaat tccaaacagc
    27061 gctttgataa caactgaaat ccccaccata ccacctgaag caatattatt atcaacaaac
    27121 attgtgttaa agccgatagc tgtgatgaag gaaccaatgg ttacaaatag taaatccatt
    27181 accctttttt tcatatttaa tacctccttt atcgtttagt aaacataata gacccattat
    27241 ctcctaaaag aatagaaacc gtcaagccct attgcttaaa aatcttagca gcttgacaaa
    27301 tcacttaaaa tgtcatagaa tgaccctaaa ctagatgagt aatctttccc ttgtttttag
    27361 agagctagtg gttggtgaga gctagcagca agcaagatga aatgggctag tggatctttt
    27421 gagaggaaac cataactttc aggcctggca ccccttatcg tgcaatttct tgagttgaga
    27481 agatgagata gtattgattg atcagagata ctaattgagg tggtaccgcg tatttattgt
    27541 aatgacgccc tcacgcaagc cttttgcgtg agggtttttg atgtcataaa atcagtatta
    27601 aggagaaatc atgacaaaac cagttatttt aacaggagat agaccaacag gaaagctaca
    27661 cttgggacat tacgtcggca gtcttaaaaa tcgtgtaagc ctgcaaaatg aaaacaagta
    27721 caagatgttt gtctttttgg cagatcagca ggccttgacg gatcacgcca aagaatctga
    27781 gatgattcgt gagtctattt tcaatgtcgc attggattat ctttctgtcg gcttggatcc
    27841 aagtaagtca actattttta tccaaagtca ggttcctgaa cttgcagagt taacaatgta
    27901 ctatatgaat ttggtgtctc ttgctcgctt ggagcgtaat ccaaccgtta aaactgaaat
    27961 tgctcaaaag ggctttggtg agagtattcc agcaggcttt ttggtttacc caatttctca
    28021 agctgctgat atcacagcct tcaaagctaa tgtagttcct gttggtaatg atcaaaggcc
    28081 aatgattgag cagacacgtg aaattgtaag aagctttaat catacctata agacagcctg
    28141 cttgattgag ccagaaggtc tttacccaga aaatgaaaag gcaggacgtc taccagggct
    28201 tgatggcaat gctaaaatgt ccaaatcact gggtaacggc atctatcttt ctgatgatgc
    28261 tgacactgtt cgtcaaaaag tcatgagtat gtataccgat ccaaatcata ttcggattga
    28321 ggatccggga cagctagaag gtaatatggt ctttcattac ctagatattt ttggccaaaa
    28381 agaggacaaa gctgatattg aagcgatgaa agagcattac caaagaggtg gccttggaga
    28441 tgttaaaacc aagcgttatc tgctggatat tttggaaaga gagcttgcgc caattcgcca
    28501 acgccgattg gaatacgcca aggataaggg cgaggtcttt cgtatgctag aagcaggaag
    28561 tcaaaaagca caggcagtgg ctgcccaaac attgtctgaa gtaaaggttg ctatggggat
    28621 tcgttatttt taatagcgta gaggctgaga atgattcttg gcctcttatc ttttcaaatg
    28681 cacctatcac tcatgagtca aaacctgtct ttttaattta cagaaatata tagaattatg
    28741 ttattgacaa atgaatttag cgtgatatga tagtaacaat aaaaataggc tggggtaata
    28801 ttccctaaaa aagaagaaaa gaggattgtg ttaatgtcaa attgggacac taaatttttg
    28861 aaaaaaggct acacgtttga tgatgttttg cttattccgg cagaaagtca tgttcttcca
    28921 aatgaagtca atttaaaaac caagcttgct aaaaatttga cattaaatat tcctattatt
    28981 accgcagcca tggacactgt aacagacagt aaaatggcta ttgcgattgc gcgtgcaggt
    29041 ggtcttggtg ttattcataa aaacatgtca attgctgagc aggctgagga ggtgcgtaag
    29101 gtcaagcgct ctgaaaatgg tgtcatcatt gatccgtttt tcctaacgcc tgagcacaag
    29161 gtagctgagg ctgaggaatt aatgcagcgc taccgtatta gtggtgttcc gattgtagag
    29221 accttagcta accgcaaatt agtcgggatt attactaatc gtgacatgcg ttttatttct
    29281 gattacaacg ccccgatctc agaacatatg acaagtgagc agctggtgac agctgaggtt
    29341 gggactgacc ttgagacagc agagcgtatc cttcatgagc atcggattga aaagctacca
    29401 ttggtagatg ataatggccg tctttcaggt ttgattacaa tcaaggatat tgaaaaggtt
    29461 attgagtttc cacatgctgc aaaggacgag tttgggcggt tgctggtagc ggctgcggtt
    29521 ggtgttacat cagatacctt tgagcgtgca gaggctttat ttgaagctgg tgcagatgct
    29581 attgttattg atacagctca tggacattcc gcaggtgttc ttagaaaaat tgcggagatt
    29641 cgcgcccact tccctgataa aaccttgatt gcaggaaata ttgctactgc tgaaggcgcg
    29701 cgtgcccttt atgacgcagg ggttgatgtg gttaaggttg gtatcggacc aggctcaatt
    29761 tgtacaactc gtgtcattgc tggtgttggg gtacctcaag ttacagctat ttatgacgca
    29821 gctgctgttg ctcgtgaata tggcaaaacc attattgctg atggtggtat taagtattca
    29881 ggagacattg taaaagccct tgcagcaggc ggcaatgctg tcatgttagg ctctatgttt
    29941 gctgggacag atgaagctcc aggtgagact gaaatttacc aaggacgcaa gtttaaaact
    30001 tatcgtggca tgggatcaat tgcagctatg aaaaaaggat caagcgaccg ttacttccaa
    30061 ggctctgtta atgaagccaa caagctagtg ccagaaggta ttgaaggacg tgttgcttat
    30121 aagggagctg cctctgatat tgtctttcaa atgcttggtg gtattcgctc aggtatggga
    30181 tatgttggag ctggtactat ccgagaattg catgacaatg ctcaatttgt agagatgtca
    30241 ggagctggtc tgattgaaag tcacccacat gatgtccaaa tcacaaatga agcaccaaat
    30301 tattccatgc attaatcctg caggtgttta cttgatgtag tatttgacat atctatttta
    30361 aaagctgaga tattttctcg gctttttttg ttgcacgatt aaaccatgat tagaaatgac
    30421 agcttgctag ccctagctat ttgcttttta gctttgtgat atttcaatgc taggctaatg
    30481 atcaaatcat actgaatgct cttaagcgta ataccttcca aaaatggcat aaccctaaaa
    30541 ggattaactt aaatagacat gaaatattgt gaaatataga aatcatgtta aaataatatt
    30601 attaaatagt taaattaaaa agaaatatac caaaatgatt ccatttattt ttgggaattt
    30661 atcgataagt ataggaatga tataggagta tagacatgaa taggttttta aagatcagtc
    30721 tgcttattgt tggtgttatt gtcattatgc ttggcatgga agtaaagcat agaatggata
    30781 tatacgatca aatcaagcag gaggagataa aaattgccca aagtaaagaa gcaattgtga
    30841 tttatgaaca ggagttaaaa tggttggacc caaatgcatt gacaaatgaa gggactatta
    30901 aatcctattc tattgattta gactcaataa ctcttaatcc aatgggaggc ttttccattg
    30961 ctttacatat aaacaaaaat ccaaagtata agtatcgaat aagtttaatg tggaatacac
    31021 caatgagaga tttatgtgtg ggaggatcct ctttgtcgcc agaattacaa gaattgttag
    31081 ataggtaatg attatgacag gctatcagaa acaattgatt gcaccaaaga acaatataat
    31141 tttcatgaaa aggagcatag ttatgaaaac attgttaaaa ctcattgtat ttattgttgg
    31201 tactcttgta cttatgcttg gcatggaggt aaagcataga atggatacat acgatcaaat
    31261 caaacaggta gagctcaaaa acgcgcatag taaagaagtg attgaaatgt atgaacagga
    31321 gctaatatca atggatcccc aggccctaac agatgaagga cttatcaagt cctacactat
    31381 cgactcagat tcactcttta ttaatccgat gggaggcttt tccattcatt taattatcaa
    31441 tgatgatcca gatatttact tgagagttgg ccttggtaga tatgatatgg aaagaaattt
    31501 ggagattgat ggtatctatc gctcagaaaa gttagaaaaa ctactaaaag gagtggagag
    31561 atgaaaacat tgttaaaact tattgtattt attgttggtg cccttgtact tattcttggc
    31621 atggaggtaa agcatagaat ggatatatac gatcaagtca aacaggtaga actcaaaaac
    31681 gcgcatagta aagaagcgat agacatttat gaaaagaagt taaaaagatt ggatcctcag
    31741 gccctaacag atgaagggct tatcaagtct tatactattg actcagactc aa
//
LOCUS       DARYNN010000022        31394 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.022, whole genome shotgun sequence.
ACCESSION   DARYNN010000022 DARYNN010000000
VERSION     DARYNN010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31394)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31394)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31394
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.022"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            <1..174
                     /locus_tag="TVB59_000967"
     CDS             <1..174
                     /locus_tag="TVB59_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1009871.1"
                     /translation="EAKKPEQPKPMTKPGAKKPEQSLPSTGDIRNPFFTPAAIAIMIA
                     AGTIAIPKRKEED"
     gene            complement(420..734)
                     /gene="trxA"
                     /locus_tag="TVB59_000968"
     CDS             complement(420..734)
                     /gene="trxA"
                     /locus_tag="TVB59_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEL1009872.1"
                     /translation="MAHIVTDATFEAETNEGLVLVDFWATWCGPCLMQAPILDQLAAE
                     IDEAELKIVKLDVDDNPNTAQQFGIMSIPTLLFKKDGKVVKQVAGVHTKDQIKAIVAE
                     LS"
     gene            914..2233
                     /locus_tag="TVB59_000969"
     CDS             914..2233
                     /locus_tag="TVB59_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEL1009873.1"
                     /translation="MEAYELIVIGFGKAGKTLAAKMAQLGKRVALIEQSPTMYGGTCI
                     NIGCIPTKALITAAEHNASFADAMAHKDTVVHRLRQKNEQLLAQSGVTLYNGKASFVS
                     NKTIQVEAGQERILLEGKHIVINTGAVSNRFPIPGLADSQHVVDSTGILALTEQPQRL
                     AIIGAGNIGLEVASLYASLGSEVTMYEAAPAILGRYEPVVAELAQDYLEKAGVTFKLS
                     ATVELIANDEAGRVLVTANGKTEAFDCLLYAMGRKPATQGLGLENTDIKLDDRYAVVV
                     DDYCQTTVEGLYAVGDVNGGPQFTYTSLDDFRIVFGQLTGTSQYNHKDRGYLPTTVFI
                     EPPLSQIGLTEKEAKEQGLPYKANELLVANMPRAHVNNDLRGIFKVIVNTETNEILGA
                     TLFANNSHEYINLIKMAMDNQIPYTYLKNQLFTHPSMAENLNDVFNL"
     gene            complement(2573..4909)
                     /locus_tag="TVB59_000970"
     CDS             complement(2573..4909)
                     /locus_tag="TVB59_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEL1009874.1"
                     /translation="MEKKILEQLEFEKVKEQFWPYLQTEQGQLELDLLEPIANKDKIQ
                     AYFTELEEMAAIFVEHHHFALGGLSDVSESMQRLDLEADLSIQELLAVKKLLQVSAEV
                     CRFYADLENVDLVALKALFEKIESFPSLQGSLQAINDAGFVEGFASPELESIRRQISN
                     KEHASRQLLQDILKKQAAYLSESLIASRNGRSVLPVKNTYRHKVAGVVHDMSASGSTV
                     YIEPRALVSLNEELTQLQTDERHEIGRILHELSEQLRPHSRSLRNNAWLLGHLDLVRA
                     KYLYMQAKQATVPVISDDKSLQLLNARHPLIQNPVANDLHFANDLAVIVITGPNTGGK
                     TIMLKTLGLAQVMAQSGLPILADKGSRVAVFNGIYADIGDEQSIEQSLSTFSSHMTHI
                     VEILNQADSDSLILFDELGAGTDPQEGASLAMAILEQLRLTNIKTMATTHYPELKAYG
                     IEIAYVENASMAFDNVSLKPTYRFMQGVPGRSNAFDIARRLGLAEHIVKEAQAMTATD
                     HDVNRIIEQLEQQTLESRKRLEHIKEVEQDNLKFNRAVKKLYNEFSHAKDKELEKAAL
                     EAREIVDIALAESDSILSQLHEKAELKPHEIIEAKHRLKQLAPEQSLSQNKVLKKAKK
                     WRAPRVGDDIIVTAYGQRGTLLAQLKDKRWEAQVGLIKLTLKEDEFSLVKLKEEAQQP
                     KKRAVKVVKKAATGKGPRARLDLRGKRYEEAMQELDAFIDQALLNNMSQVDIIHGIGT
                     GVIREAVGKYLRRNKHVKSFGYAPQNAGGSGCTIANLG"
     gene            complement(4982..5527)
                     /locus_tag="TVB59_000971"
     CDS             complement(4982..5527)
                     /locus_tag="TVB59_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEL1009875.1"
                     /translation="MLSVLILLLLSWSFYIGYNRGLILQTFYCFGALVSLLFAHHGYK
                     ALAGKLALWVPYSNPAEGAATLFFKDINIFELDKVYYAGIAFFILSTVGYAVVRLAGV
                     LVHLAPVDYFDGFEAKLASGLLAVMVSVLFLSMALTVLATIPMPFIQGRLHGSLLSRL
                     LVEHCPFISSILRQLWVTAIL"
     gene            complement(5527..5838)
                     /locus_tag="TVB59_000972"
     CDS             complement(5527..5838)
                     /locus_tag="TVB59_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009876.1"
                     /translation="MKNINRYKLTFGEKTLTLTTDKDNLFMEEVDRVAKEKYQAIKER
                     LPEADDETVAILMTINTLSAQLSREIEIEKIEAEIVELREKALAGIQEKASQADTDEV
                     S"
     gene            5956..6864
                     /locus_tag="TVB59_000973"
     CDS             5956..6864
                     /locus_tag="TVB59_000973"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEL1009877.1"
                     /translation="MDTLVFKINSQVSSSLIKQLAPYRISNANPYVRLAAKKDGVTLM
                     LYTSGKLVLQGRQAAKLAQELDLQETPADQRPAPSSAQDIPLIGSDEVGNGSYFGGIA
                     VVASFVQPEEHALLRQLGVDDSKNLNDKSIAQIAPVLKKHIQHRALLLSPKKYNEMVG
                     KGKPYNAVSVKVALHNQAIFLLLNDGARPEKIVIDAFTSQANYDKYLQQEKNHFRNPL
                     TFEEKAEGKYLAVAVSSIIARQLFLDNLDKLSQDLGYRLPSGAGRPSDQIASQILAAY
                     GMAGLEHCAKLHFANTKKAQALLKKQ"
     gene            6889..7488
                     /gene="lepB"
                     /locus_tag="TVB59_000974"
     CDS             6889..7488
                     /gene="lepB"
                     /locus_tag="TVB59_000974"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEL1009878.1"
                     /translation="MKQFIKEWGAFTLFILLFGLSRLFLWQPVKVDGHSMDPTLAHGE
                     RLIIFNKAKIDRFDIVVASEEDENGQRKEIVKRVVGMPGDKLSYRNDTLYINNKKTKE
                     PYLDTYLTSFKKDKLQSTYAYSDLFQELAENAAAFTVNSEGKTEFDITVPKGEYFLLG
                     DDRIVSRDSREVGSFKKQDIVGEVKFRFWPLNKINLFPR"
     gene            7717..10116
                     /locus_tag="TVB59_000975"
     CDS             7717..10116
                     /locus_tag="TVB59_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEL1009879.1"
                     /translation="MEHFFTGTVDRIIFDNASNFFKILLLAIEDTDSDFDEADIVITG
                     TMAEIIEGEAYTFWGELTQHPRYGQQLRLSRYQKAKPTSAGLVSYFSSEHFKGIGQKT
                     AEKIIALYGNNPIDEILKNPSRLNEISSLSKANREAFVAKLKANYGTEQVIAALADLG
                     LANRFAFQLFDKYKEEAVHIVKDNPYQLIEDIQGFGFKLADSLAEQLGIESASPKRFR
                     AALLHCLLEQSIKRGDTYIQARELLALTISLLEDTRPVECDPAIVANQLTQLIDEGKV
                     MTIGTRVFDSSLYYAEDGIQKHLTRLLQQPLTKEPSQDTIDQEIQAIQEELAITYDKI
                     QKQAISQALTSKVFILTGGPGTGKTTVIRGILQAYASLYQIDLKQKDIPIILAAPTGR
                     AARRMNELTGLASATIHRHLGLNGDNDYQAMEDYLDCDLLIVDEFSMVDTWLANQLLT
                     AINSNTQLIIVGDSDQLPSVGPGQVLADLLKVDRIPHITLDKIFRQSEESTIVDLANH
                     IRQGILAPDFCQKKADRSYFEAQAPFIPGMMTKIVQAALKSGIPAEEIQILAPMYKGL
                     AGINSLNQLMQNLLNPLANQTEFLFNETAFRKGDKVLHLVNDAQLNVFNGDIGYITDL
                     IPAKYTESKQDEIIMDFDGTEIVYPRNEWLKITLAYAMSIHKSQGSEFQVVILPVTRQ
                     SGRLLQRNLIYTAITRSKSKLIMLGEIAAFEEAIKKEGDKRHTYLVQRLQVAEADDHT
                     AAASVKESNQSSLSVMPATSPQKEQEQPPYLLTPHNFLAIDPMIGLTEDDMLTFFKKK
                     S"
     gene            10212..10697
                     /locus_tag="TVB59_000976"
     CDS             10212..10697
                     /locus_tag="TVB59_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009880.1"
                     /translation="MISYEQVRQALRTSTITIIIINAISMVITLFGLAGIFFLKSQLD
                     KPEFRAQFSAEQLRLFEVGISPFTIFMSVISLGLVVLTTVLCGFNLSKIKQGSTVSYV
                     PYIIGIVLYLISIVSQLFSQIEPVSMIIVLAELALYGFAFYKAKTLNEKDKDNPQSIE
                     E"
     gene            complement(10840..11943)
                     /gene="dinB"
                     /locus_tag="TVB59_000977"
     CDS             complement(10840..11943)
                     /gene="dinB"
                     /locus_tag="TVB59_000977"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEL1009881.1"
                     /translation="MLIFPLINDTSRKIIHIDMDAFFAAVEERDNPELKGKPVVIGKN
                     PRESGGRGVVSTCNYEARRFGIHSAMSSKEAYERCPQAIFISGDHAKYRRIGYDIREI
                     FKRYTDQVEPVSIDEAYLDVTTNKLGIKSALKIARLIQHDIWNSLQLTCSAGVSYNKF
                     LAKLASDFEKPHGLTLVLPDDALPFLEKLPIEKFHGVGKRTVERLHEMGIYTGQDLLR
                     VPEMTLIDQFGRFGYELYRKARGISHSPVKPNRMRKSISSERTYAKLLYQEADIKAEL
                     SKHARRVADLLEANKKLGRIIVLKVRYADFTTLTKRVSLPELTRDARIIDQVARELFD
                     SLEEHQAGIRLLGVTMTGLKDKVTDILLDLSFN"
     gene            12152..14476
                     /gene="pflB"
                     /locus_tag="TVB59_000978"
     CDS             12152..14476
                     /gene="pflB"
                     /locus_tag="TVB59_000978"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEL1009882.1"
                     /translation="MATVKTNADVFEKAWEGFKGTDWKEKASISRFVQANYTPYDGDE
                     SFLAGVTERSLHIKKVIEETKAHYEATRFPYDTRPTSIADIPAGFIDKDKELIFGIQN
                     DELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKHVTTVNDGIFRAYTSNIRRA
                     RHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAITEIDEESIRLREEI
                     NLQYQALGEVVKLGDLYGVDVRRPAENVKEAIQWVNIAFMAVCRVINGAATSLGRVPI
                     VLDIFAERDLARGTFTESEIQEFVDDFVLKLRTVKFARTKAYDALYSGDPTFITTSMA
                     GMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYAFRRYCMHMSHKHSSI
                     QYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNGGY
                     DDVHKDYKVFDIDPVTDDVLDFDTVKANFEKSLDWLTDTYVDALNIIHYMTDKYNYEA
                     VQMAFLPSHQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYPRW
                     GEDDPRSNELAEWLIEAYTTRLRSHKLYKNAEATVSLLTITSNVAYSKQTGNSPVHRG
                     VYLNEDGTTNLSQLEFFSPGANPSNKAKGGWLQNLNSLASLDFSYAADGISLTTQVSP
                     RALGKTHDEQVENLVTILDGYFENGGQHVNLNVMDLNDVYDKIMAGEDVIVRISGYCV
                     NTKYLTPEQKTELTQRVFHEVLSMDDAAEAISGK"
     gene            14784..15062
                     /locus_tag="TVB59_000979"
     CDS             14784..15062
                     /locus_tag="TVB59_000979"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009883.1"
                     /translation="MKRLKTLCLLATAITLTLAPISTSQTTTQTVYASETHQNLCTNT
                     GNGWFKCPDGHGGWTWHFDENHKSNQQSFLGGLLGFALSLWGAIIRLF"
     gene            complement(15226..16167)
                     /locus_tag="TVB59_000980"
     CDS             complement(15226..16167)
                     /locus_tag="TVB59_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEL1009884.1"
                     /translation="MTLEVIEKVSQQIQEGLYHGASLALFRCGGWQEHYIGTLDGQRP
                     VTKGLVYDLASVSKVVGVATVCIAMINSGALALDTPLRHYYPDAQKLEVTLRQLLTHT
                     SGLDPYIPNRDQLNAQQLRAAMHQLQVKDDKTFHYTDVNFLLLGFMLEHLHGKSLDEL
                     FQEMVFTPFGMTETSFGPRPEAVPTVKGVLDGEVHDPKAKVLGNHAGSAGLFSTIRDL
                     ERFIEHYLKESFSDRLFQSYSRQEKPRSLGWSLEGDWISHTGYTGPFIMLNKKEQQAA
                     IFLTNRTYDKDDRALWIKERRQLRDAIHRTFDRNSPR"
     gene            complement(16164..16919)
                     /locus_tag="TVB59_000981"
     CDS             complement(16164..16919)
                     /locus_tag="TVB59_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEL1009885.1"
                     /translation="MTLFDNIVFKTPVLRVNNRDLNIAFYQKNLGLRLVSEENAISIF
                     SSWGQGQERFVIEESPAARTRVVDGPKKVNTIVIKTTAPKDIEQLLAHGVDYDLIFKG
                     KKGYAFEVTSPEGDRFLLHAEDDIKELDIVDDVPAIDKEADFRGLSQFSFDLIVLNVL
                     DDEQSRAFYQSIFGDCLPVTLEFNREAGQDLTIVPHVTWDLEILEFQVSDSYDLLALK
                     TYLEDKGCQVYLDKKARVLVLSDPSQIEIWFVK"
     gene            complement(17412..18260)
                     /locus_tag="TVB59_000982"
     CDS             complement(17412..18260)
                     /locus_tag="TVB59_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEL1009886.1"
                     /translation="MEITWTVKYITEFIATAFLIILGNGAVANVDLKGTKGNRSGWLV
                     IAFGYGLGVMMPALMFGNVSGNHINPAFTFGLAVSGLFPWAHVLQYVLAQLLGAMFGQ
                     LVVVAVYKPYFVQTDNPNNILGSFSTISAVDDGDKGSRKAAYINGFLNEFVGSFVLFF
                     GAMALTKNYFGVELVGKLVEAGYDQTTAATQISPYVTGSLAVAHLGIGFLVMTLVTSL
                     GGPTGPALNPARDLGPRLVHHFLPKSVLGQAKGDSKWWYSWVPVAAPVLAAVAAVAAF
                     KFLYIK"
     gene            complement(18362..18814)
                     /locus_tag="TVB59_000983"
     CDS             complement(18362..18814)
                     /locus_tag="TVB59_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEL1009887.1"
                     /translation="MISKYKRILAAVDGSYESELAVEKAINVALRNDAVLLLAHVIDV
                     KAYQGDAMVSDYVFDTQEEHAKEVLRYYEKMARGRGVSSIKKIIERGNPKKLLASDIP
                     EKEQADLIMVGATGLNTFERLLIGSTSEYILRHAKKDLLVVRNCEKTL"
     gene            complement(18834..20033)
                     /locus_tag="TVB59_000984"
     CDS             complement(18834..20033)
                     /locus_tag="TVB59_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1009888.1"
                     /translation="MEDKLFNKHFIGITVLNFIVYMVYYLFTVIIAFVATKELGAKTS
                     EAGLATGIYILGTLLARLIFGKQLEVFGRRLVLRGGAIFYLLTTLAYFFMPTIGMMYF
                     VRLFNGFGYGVVSTATNTIVTAYIPASKRGEGINFYGLSTSLAAAIGPFVGTFMLDNL
                     HIDFRMIIILCSVLIAVVVLGAFAFPVTDIALNSEQLAKTKSWTVDSFIERKALFITL
                     IAFLMGIAYASVLGFQKLYTTDIHLTTVGAYFFVVYALIITITRPAMGRLMDVKGEQW
                     VLYPSYLFLALGLFLLGSVTSSLPYLLSGALIGFGYGTFMSCGQAASIKGVEEHRFNT
                     AMSTYMIGLDLGLGAGPYLLGLIKDMLLGSGVQSFHQLFWLAGLIPAACAVMYFLKTQ
                     AKAIDKG"
     gene            20202..20861
                     /locus_tag="TVB59_000985"
     CDS             20202..20861
                     /locus_tag="TVB59_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEL1009889.1"
                     /translation="MNHQILQRYIDSHNFPIIEKGYHKYLTFESLEEDFTYILKEGIV
                     KQSVLSKYGMEFNLRYVTGLEITSVLNTGYSKDMREPYNVRIESETASFYKVRHSTFL
                     RDISEDIELQGYVKDFYHYRLQKSMKKMQCMLTNGRIGAISTQIYDLMTLFGRPLANG
                     HILIDFIITNEELGKFCGISTASSVSRLLKQLKKEGIIQINDQHIIITNLEKLKDNIV
                     F"
     gene            20882..23167
                     /locus_tag="TVB59_000986"
     CDS             20882..23167
                     /locus_tag="TVB59_000986"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEL1009890.1"
                     /translation="MRYNQLSYIPTSLETAVAELQALGFAVQQEQAPKENFAIFLRKL
                     FFHFQDTDYPLSHMIASKDLDLLTFLTSDATLTKEVFDLVALQVLGFIPAVDFTDAQD
                     FIQKIGFPIVFDSQQLLLNLHQLLATRQKSGVTLIDSLVSQGLLPMDNCYHYFNGKAL
                     ATFDTTSLIREVVYVEAPLDTDQDGQLDLIKVNIIRPKASTAIPSMMTASPYHQGINE
                     TANDKKLHRMEGELSPKAPRRITVEPTDFQPLATKPSRLPVNECQETFSHISSYTLND
                     YFLARGFANLYVSGVGTAGSTGFMTSGDYAQIESFKAVIDWLNGRATAYTSHKRDYQI
                     KADWSNGLVATTGKSYLGTMSTGLATTGVDGLAVIIAEAAISSWYDYYRENGLVCSPG
                     GYPGEDLDVLTELTYSRNLLPGDYLRHNDHYQQLLSQQSQALERQSGNYNQFWHDRNY
                     LPQADRIKCEVVYTHGLQDWNVKPRQVYNIFNALPDSLGKHLFLHHGEHVYMHNWQSI
                     DFREAMNALLCQKMLGQNNGFTLPTIIWQDNQKEQTWKELTAFGGHSKRQIALGDDHV
                     LIDNHYGEEDFKRYSKDFRAFKAELFEGKANQAVIDILLEEDLPINGQACLKLKLKSS
                     ENKGILAAQLLDYGKKKRFADIPAILELDSIDNGQQFAREALKELPFKDSPYRVVTKG
                     VLNLQHRSDLLTIEDIPNDQWMTITFHLQPTIYHMAKGDTLRVVLYTTDFEHTIRDNS
                     NYALTLDLEQSYLLIPTDEEE"
     gene            complement(23273..23665)
                     /locus_tag="TVB59_000987"
     CDS             complement(23273..23665)
                     /locus_tag="TVB59_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HEL1009891.1"
                     /translation="MLTEEMKEMIAEQLAMVVTVDNEGNPNIGPKRSMRLLDDETLVY
                     NENTGGQTCSNIQANGKIEVAYVNREQLRGYRFVGRAEIITEGPVFEAAKEWAEGKMG
                     APKAAGLIHIESVYSLHSGAEAGKKVSK"
     gene            complement(23819..24076)
                     /locus_tag="TVB59_000988"
     CDS             complement(23819..24076)
                     /locus_tag="TVB59_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1009892.1"
                     /translation="MSKATLKELRIAQKKTQKELSALTGISVRTLARYEKDVQKLRRA
                     KYEKLRGIAEALTISVDDIFFGRRFGFYEIKSACLLIAFLL"
     gene            24255..24629
                     /locus_tag="TVB59_000989"
                     /pseudo
     CDS             24255..24629
                     /locus_tag="TVB59_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678526.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(24887..25669)
                     /locus_tag="TVB59_000990"
                     /pseudo
     CDS             complement(24887..25669)
                     /locus_tag="TVB59_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514970.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
     gene            complement(26186..27694)
                     /locus_tag="TVB59_000991"
     CDS             complement(26186..27694)
                     /locus_tag="TVB59_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1009893.1"
                     /translation="MLEEYLEPVINHQALLLTILLGKKRISFHAIQQKTGFSLANIKR
                     YIHQLEELFQGDIAFEWDSTIVRCTVLKRGKPFLKTIYRQSVRLHILKFLLIKAPCYK
                     VKSVSGFAREHFISTPSAYRLIQHMKPFVEECGLALEDNSVVGEEWRIRYLIALLHDK
                     YGIVIYELTDHDLDIVHDFIFSIKKQQTPHPLLDKKFRFFDVLLSLSWKRGEFDVAIP
                     QEGIFKRLKSLALYGYLEDFFKREGKLLLDMDFPSSEIDYIFLVYLTVNNSFSITQWS
                     EEDSSALLTIIQEDPAYQELLGELRQLFGHYIAFDKACIQTLIPYFRKTLFDLSLFIP
                     QKYYYAEEYQGSKLLANRIELMINSWAERVSGVGRLTGSNLHLLCTRLEQLVREGLPP
                     LAIAVIEINKKNIDILYSLVMQQVSPCVAKVYRFNILSEAELPWRTDFDLIVTTAEMT
                     AFIEERLSLNENTKILDFNFDFVMYQAEYLSQVIRELRDKQYQEALDTILNG"
     gene            27945..28841
                     /locus_tag="TVB59_000992"
     CDS             27945..28841
                     /locus_tag="TVB59_000992"
                     /inference="COORDINATES: protein motif:HMM:NF012162.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL1009894.1"
                     /translation="MKTKSFRKVLTTSATCIVLATSFAGGTLRVWAEQLYYGWNDGTR
                     QSSPYFLYVSPKNAPKRELKDEYVVYCFNKKLYWPDQWESIYSNFNDIRSPYNDLPVY
                     EKKLGYDGIFKQYAPDYKKDISDIASALVAVLSNGYPTNKSQLSTSYHLNNDSSRKVT
                     QLAIWYFSDSLTKEYLKDTGGYNLNDMEKKALDFLISKGEDSKLKSEQSNYSLDIYVY
                     QSGGHDHMKDYQNLLGSTLIPKEPLKPQLGGFSGHNGNGLSGLEGGSSGSQETNEDGK
                     KGLIGFHGGLSGSEGKRDPFQD"
     gene            28838..29101
                     /locus_tag="TVB59_000993"
     CDS             28838..29101
                     /locus_tag="TVB59_000993"
                     /inference="COORDINATES: protein motif:HMM:NF014980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein"
                     /protein_id="HEL1009895.1"
                     /translation="MKGEAGAPDTPQKPNDPLQSLEGGNSPIVEQNYGSTEGYHGQSG
                     ILEETEDTNPPGIILGGSGNVETRSSSDGAWRWSSWRIRRNDT"
     gene            29028..29834
                     /locus_tag="TVB59_000994"
     CDS             29028..29834
                     /locus_tag="TVB59_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin binding protein"
                     /protein_id="HEL1009896.1"
                     /translation="MSKRDPHLMGLGGGLAGESGETTPKPGQTGGHGPIIETTEDTQK
                     GMSGQSGGTIESENTKKPEVMIGGQGQTIETTEDTQKGMSGQSGGTIESEDTKKPEVM
                     IGGQGQTIETTEDTQKGMSGQSGGTIESEDTKKPEVMIGGQGQIIDFSENTQSGMSGQ
                     SGDTTVIEDTKKSEIIIGGQGQIIDFSEDTQPGMSGQSGGTTIVEDTKKPTPKPKPAP
                     APIVNDEKPNKGTQLPQTNDMKQLTLSIIGAMSMLLVLCLSLFKRPSKKD"
     gene            complement(30206..31252)
                     /locus_tag="TVB59_000995"
     CDS             complement(30206..31252)
                     /locus_tag="TVB59_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEL1009897.1"
                     /translation="MRLRTYIVIGYLMSMLITIAGLIVGLNQMLITIEDISYILVIAL
                     IASVAGGIVNMILLSNVFSSLKRLKKKIQAISERNFDSGQLIKCPLEFKDLEEAFNQM
                     SSELKVSFESLSESEHEKSMMIAQLSHDIKTPLTSIQATVEGILDGVIPREEERHYLN
                     TISRQTNRLNQLVEELHMVSLNDQKQDDKQQLQIIYLEKLLIDMLSEFQLTLEQEKRS
                     VHIEVAKEVVKISSRYDALSRIMLNLVSNALKYSKANTALTIHAYQQEQSIRIDVIDQ
                     GQGIKKEDLPLIFKRLYRVEASRNMKTGGHGLGLSIARQLARQLGGDIAVESQLGKGS
                     CFSLLLPASPPLGD"
     gene            complement(31254..>31394)
                     /locus_tag="TVB59_000996"
     CDS             complement(31254..>31394)
                     /locus_tag="TVB59_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HEL1009898.1"
                     /translation="WEEEYLDDTNTLNVHIHSLRNDLAKYSTEQTPTIKTVWGLGYKL
                     EG"
BASE COUNT         9385 a         7384 c         6253 g         8372 t
ORIGIN      
        1 gaagctaaga agcctgaaca acctaaacca atgactaaac caggagctaa gaagcctgag
       61 caatcacttc catcaactgg tgacatcaga aatccattct tcacgcctgc agctattgct
      121 attatgatcg cagcaggtac cattgccatt ccaaaacgca aggaagaaga ttaaacaaat
      181 taacaatccc catatttcaa caatgataca caagccccta cttgtgtcca cctcaaaagc
      241 agtagccagt cgcgcggcta ctgcttttac tatgcttttt ttacaccagc tctgatagca
      301 gctaataaca aaaaagattg aagacacagc ttattgggtc cccgatcttt ttttggtcat
      361 acaaccaaca gcagctcttg aggcttgctg tccttctaag aggctgttgg cttgttgctt
      421 tagcttaatt ctgctacgat agccttgatt tgatccttgg tatggacgcc tgctacttgc
      481 ttgacaacct taccgtcctt tttgaacagc agggttggga tagacataat gccaaattgt
      541 tgagcagtat tgggattgtc atcaacatct agcttgacaa tcttaagctc agcttcgtca
      601 atttctgctg ctaattgatc aaggattggc gcttgcatta agcaagggcc gcaccaggtt
      661 gcccaaaagt ccacaaggac taggccttca ttagtttctg cttcaaatgt tgcatctgtt
      721 acgatatgtg ccattgtaat ctccgttctt atagtttata agcctatttt aggggaaaac
      781 gactgataat gcaagaatct gatacgaaga cctcggtctt atgatttaag aaaaatctgg
      841 cgtagccatt ttaagacaaa tacgctggcc tttgctacaa tgaccttatc ttaacaacta
      901 aaaggaggct actatggaag catacgagct tattgtgatt ggatttggta aggccggaaa
      961 aactttggct gccaaaatgg cgcagctagg aaaaagagtt gcccttattg agcagagccc
     1021 cactatgtat ggcgggactt gtatcaatat cggctgtatt ccaacaaagg ccttaatcac
     1081 tgctgctgag cataatgcta gctttgcaga cgctatggcg cacaaagata ctgttgttca
     1141 tcgtcttcgc caaaaaaatg agcagctgct agctcagtct ggtgtgacac tttacaacgg
     1201 taaggcaagc tttgtctcta ataagacgat tcaagtagaa gcagggcagg agcggatcct
     1261 cttagagggc aagcatatcg tgatcaatac cggagctgtt tcaaatcgct ttccgatacc
     1321 tggtctagca gatagtcagc atgtggttga tagtacaggg attctagctc tcactgagca
     1381 gcctcagcgc ttggctatta tcggtgcggg gaatatcggg ctagaggttg ccagccttta
     1441 tgccagctta ggcagcgagg ttactatgta tgaggctgca cctgctattt tagggcgcta
     1501 tgagccggtt gtcgctgagc tggcacagga ttacctggaa aaagctgggg ttacctttaa
     1561 gctctctgcg actgttgagc tgattgctaa tgatgaagca ggtagagttc tagtgactgc
     1621 taatggcaag acagaagcct ttgattgtct cctctatgct atgggacgta agcctgccac
     1681 tcaaggcctt ggcttggaaa acactgacat taagcttgat gatcgctatg ctgtcgtggt
     1741 agatgattat tgtcaaacca ctgtcgaggg gctatatgcg gttggtgatg ttaatggcgg
     1801 gcctcaattt acctatacgt ccttagatga tttcaggatt gtgtttgggc agctaacagg
     1861 cacaagccag tacaaccaca aagatcgggg ctatctgcca acaacagtct ttatcgagcc
     1921 gccactttca caaattggtc taacagaaaa agaagcaaaa gagcagggac tgccctacaa
     1981 ggctaatgag ctcttggttg ccaatatgcc acgcgcccat gtcaataacg acctcagggg
     2041 gatttttaag gtcattgtca atacagagac taatgaaatt ctaggggcaa ccttatttgc
     2101 taacaattct cacgaataca ttaacctgat taagatggct atggataacc agattccata
     2161 tacctatctc aaaaaccagc tctttaccca cccgtcaatg gctgaaaatc ttaatgatgt
     2221 ctttaacctt taaaagaacc tcaacctcac ctgcatagca ggtacaacag ccaaactatt
     2281 aaaaaaacaa actccttttt ggctgcttat cacatggata ggcggctagc aaaaggagct
     2341 tgttttttct tgtatccaat cagcaggcta gcagctgctc atggtctaaa ggaactagct
     2401 aggctgggac acgttggtag caaaagtcca gcaagactca ctagctgctg tcatgagctt
     2461 tgaagagcag cacttaggga acacgcccag tagctttctt tgggacgctt ggctcaccta
     2521 gggctcaatc agcttgagta aaaaggggct ttatttgaat caagaggatc aattagccta
     2581 gattagctat ggtacagcct gagccgccag cattttgcgg ggcatagcca aagcttttga
     2641 catgcttgtt gcgtcgcaag tacttgccga ccgcttcacg tataacacct gtaccaatac
     2701 catgtatgat gtcaacctga ctcatgttgt taagcaaggc ttggtcgata aaggcatcta
     2761 gctcctgcat ggcctcctca tagcgcttgc ctcgaaggtc taagcgagcg cgcggccctt
     2821 ttcctgtagc tgcttttttg acgaccttga cagctctctt cttaggctgc tgcgcttctt
     2881 cttttagctt aaccaagctg aattcgtctt ccttgagggt caacttgatc aggccaacct
     2941 gagcctccca cctcttgtcc ttaagctggg caagcaaggt tcctctttgc ccataggcgg
     3001 taacaatgat gtcatcaccc acacgaggag cccgccattt tttcgctttt ttcagcacct
     3061 tattttgcga caggctttgc tctggcgcaa gctgctttag gcgatgcttg gcttcgataa
     3121 tttcgtgcgg ctttagctct gccttttcat gcagctgact taaaatgcta tcactttctg
     3181 ccaaggctat atccacaatc tcacgcgctt caagggctgc cttttccaat tccttgtcct
     3241 tagcgtggga gaactcgtta tagagctttt taacagcacg attgaatttg aggttatcct
     3301 gctcgacctc cttgatatgc tcaaggcgct tgcggctttc taacgtttgc tgctctagtt
     3361 gctcaatgat acgattgaca tcatgatcag ttgcggtcat cgcctgagct tccttgacga
     3421 tgtgctctgc taagcccaat cgtctcgcaa tgtcaaaagc atttgagcga ccaggcactc
     3481 cttgcatgaa gcggtaagta ggctttaggc tgacattgtc aaaggccatg ctggcatttt
     3541 caacataggc tatctcaatc ccataggcct ttagctctgg gtaatgggta gtggccatcg
     3601 tcttaatatt ggtcagacgc agctgctcca aaatagccat agcaaggctg gctccttcct
     3661 gtggatcagt ccctgctcct agctcgtcaa agaggatcaa gctgtcactg tctgcctgat
     3721 tgagaatctc aacaatgtga gtcatatgac tggaaaaggt agacaggctt tgctcaatgg
     3781 attgctcatc tccaatatca gcataaatac cattaaaaac tgccaccctg gagcccttgt
     3841 cagccaaaat aggcagccct gactgggcca tcacctgagc aagccccaag gttttgagca
     3901 tgatggtctt accacctgta ttaggaccgg tgatcacaat tactgctaag tcatttgcaa
     3961 aatgcagatc atttgccaca gggttttgaa tcaaggggtg gcgcgcattg agcagctgta
     4021 agcttttatc gtcagaaatc actggcacag ttgcctgttt ggcttgcata taaaggtatt
     4081 ttgctctcac aagatctaaa tgtcctagta gccaagcgtt attcctaaga gatcgactat
     4141 gcggacgcag ctgctctgac agctcatgca agattcgtcc aatctcatgg cgttcatctg
     4201 tctgtagctg agtcagctcc tcattgagac ttacaagcgc tctaggctca atgtagaccg
     4261 tactgccaga agctgacatg tcatgcacaa cgcctgccac cttatgacga taggtgtttt
     4321 tgacaggcag gacacttcgg ccattacgac tagcaatcag gctctctgac aaataagctg
     4381 cctgtttttt taggatatcc tgcaggagct gacgactggc atgctccttg tttgatatct
     4441 gacgacgaat gctctccaat tcaggactag caaagccttc aacaaagcct gcgtcattaa
     4501 tggcttggag actcccctgt aagctaggaa agctctctat tttttcaaag agtgctttta
     4561 gagcgactaa atcaacattt tccaaatcag cgtaaaaacg acagacctct gccgacacct
     4621 gcaggagctt tttaactgct aaaagctctt gaatgctcag atctgcctct aaatccaaac
     4681 gctgcatgct ttctgagaca tctgatagcc ctcccaaggc aaaatggtgg tgctctacaa
     4741 aaatagccgc catttcctca agctctgtaa agtaagcctg tattttgtct ttattcgcaa
     4801 taggctccaa caagtcaagc tctagctgcc cctgctctgt ctgtaaataa ggccaaaatt
     4861 gctctttaac cttttcaaat tctaactgtt ctaaaatctt tttttccata gttcttatta
     4921 tacctaaaaa tcacttaaaa tgtgggacac taaacaaaaa gagaccagag agactctgac
     4981 ctcaaagaat agctgttacc cataattgcc tgagaatgct tgagataaag ggacaatgct
     5041 caaccaagag gcgagacaaa agactgccat gtaggcgccc ttgaataaag ggcatgggaa
     5101 tggtagcaag aacggtcaat gccatgctta aaaacaaaac cgaaaccatc accgccagca
     5161 agccactggc tagcttagcc tcaaagccat caaaataatc caccggcgca aggtgcacca
     5221 agacacccgc caatcgaacc acagcatagc ctactgtaga cagtataaaa aatgctatcc
     5281 ctgcataata aaccttatcc aattcaaaaa tattaatatc cttaaaaaat aaggtagctg
     5341 ctccctcagc aggattagaa taaggcaccc atagagccag cttgcctgcc agagccttat
     5401 agccatgatg ggcaaacaag agcgacacca aggccccaaa acaataaaag gtctgaagga
     5461 taagccctct attgtagcca atgtaaaagc tccaagaaag cagtaacaat ataagcactg
     5521 agagcatcat gacacctcat ctgtatctgc ttgactagcc ttttcctgaa tacctgccag
     5581 tgccttctca cgcagctcga caatctcagc ttcgattttt tcaatctcaa tctctctact
     5641 cagttgggct gacagggtat tgatggtcat caaaatagca acggtttcgt cgtctgcttc
     5701 tggcagacgc tccttgatgg cctgatattt ttcctttgcc acacgatcaa cctcttccat
     5761 aaagaggttg tctttgtccg ttgtcaatgt taatgtcttc tcaccaaatg ttaatttgta
     5821 acgattaata ttcttcatag gctcacccct ttagcattat accctaaaaa tgacttttcg
     5881 taaaattgtg aaattaatct gagattgcat ggaatgattt cccataacag gacattttat
     5941 gttaaaataa tgttcatgga caccttagtt ttcaaaatca attcccaagt cagcagcagc
     6001 ctgatcaagc agctagcacc ataccgcata agcaatgcca atccttacgt tagactggct
     6061 gccaaaaaag atggtgtcac actgatgctg tatacctcag gcaagctggt gctgcaaggc
     6121 agacaggctg caaagctggc tcaagagctt gatctgcaag aaacgcctgc tgatcagaga
     6181 cccgcaccct ccagcgcaca ggatatcccc ttaattggta gtgatgaggt gggaaatggc
     6241 tcttactttg gaggcattgc tgttgttgct agctttgtgc agccagagga gcacgccttg
     6301 ctcagacagc tcggtgtcga tgattctaaa aacctcaatg ataagagtat cgcccagatc
     6361 gctcctgtcc taaaaaagca tattcaacac agggcgcttt tgctatcgcc taaaaaatac
     6421 aatgaaatgg taggtaaggg gaagccctac aacgctgttt ctgtcaaggt tgctcttcat
     6481 aatcaagcga tttttctgct cttaaacgac ggagcaagac cagaaaaaat tgtcattgat
     6541 gccttcacaa gtcaggccaa ttatgacaaa tacctacagc aagaaaaaaa tcactttcgt
     6601 aatcccttga cctttgagga gaaggccgaa ggcaaatatc tggcagttgc tgtcagctct
     6661 atcattgcta gacagctatt tttagacaat cttgacaagc tcagtcaaga tctgggctac
     6721 cggttgccta gtggtgctgg gcgtccatct gatcagattg ccagtcaaat cttagccgcc
     6781 tatggtatgg caggcttaga gcattgcgct aagctgcact ttgcaaacac caaaaaagcc
     6841 caagcgctac taaaaaaaca ataatcttag aaaaataaag gaaaagtcat gaaacaattt
     6901 attaaagaat ggggagcttt tacccttttt atcctacttt ttggactctc acgtttgttc
     6961 ctatggcagc ctgtcaaggt tgatggccac tcaatggacc caaccctagc acatggcgag
     7021 aggctcatta tcttcaacaa ggctaagatt gatcgctttg atattgttgt tgccagtgag
     7081 gaggacgaga acggacagag aaaagagatt gttaagcgtg ttgttggcat gccaggtgat
     7141 aagctgtctt atagaaatga cactctttat atcaacaaca agaaaacaaa agagccttat
     7201 cttgatacct acctgacgag ttttaaaaag gacaaattac aatcaaccta tgcttacagt
     7261 gatctcttcc aagagctggc tgaaaatgct gctgccttta ccgtcaactc cgaaggaaaa
     7321 acagaatttg acatcactgt tccaaagggc gaatatttcc tactgggtga tgaccgcatt
     7381 gtatctcgtg acagccgcga ggtcggctcc tttaaaaagc aggacatcgt tggtgaggtt
     7441 aagttccgct tttggccact caataaaatc aatctcttcc ctagatagca ggcaagctaa
     7501 agctattttc tagcagggct gatataggct ctatgcccac agcagtaaag actcagggca
     7561 gcaatagcct ctatctatat ctgcttatct atccatacca agaggcttga tgtgctatcc
     7621 aagcactcag ctagctttag agaagcagct attgttgacg ttctaaaacc tgccgttgtg
     7681 caggttttcg actatcttgc acagaaaggt accgtcatgg aacacttttt tacaggcact
     7741 gttgaccgaa ttatctttga caatgcgtca aattttttca aaattctatt actggctata
     7801 gaggatactg atagtgattt tgatgaagct gacattgtca ttacaggcac tatggctgag
     7861 atcatagagg gcgaagccta taccttttgg ggtgagctga cccagcaccc aaggtatggt
     7921 cagcagctgc gcctgagccg ctatcaaaag gctaagccca cctcagcagg tctcgttagc
     7981 tatttttcca gtgagcattt caagggcatt gggcaaaaaa cagctgagaa aatcattgcc
     8041 ctttacggta ataatcctat tgatgagatt ttaaaaaatc ccagtcggct taatgagatc
     8101 tctagccttt ctaaggctaa tcgtgaagcc tttgtggcaa agcttaaagc caattatggc
     8161 actgagcagg tgattgctgc cttggctgat ctaggactgg ccaatcgctt tgcctttcag
     8221 ctatttgaca aatacaagga agaggctgtt catatcgtca aggacaatcc ttatcaactc
     8281 attgaggaca ttcaaggctt tggctttaag ctggctgata gcttagctga acagctagga
     8341 attgagagtg cctctcccaa gcgctttcgt gcggctctgc tgcattgcct gttggagcaa
     8401 tccatcaagc gaggcgacac ctatatccag gcacgtgagc ttttggcgct gaccattagc
     8461 ctattagagg acacaaggcc agtcgaatgc gacccagcta ttgtcgctaa tcagctaacc
     8521 cagctcatcg acgagggcaa ggttatgact attggcacgc gtgtttttga cagcagcctt
     8581 tattatgccg aagacggcat tcaaaagcat ctgacacgct tactacagca gcctctgact
     8641 aaggagccta gtcaagatac cattgaccaa gaaatccaag ccatacaaga ggagcttgct
     8701 ataacctatg acaagatcca aaagcaggcc atcagccagg cactgaccag caaggttttc
     8761 attctaacag gaggcccagg cacaggaaag acaaccgtta tcaggggcat tttacaggcc
     8821 tatgccagcc tgtaccagat tgacctgaaa caaaaggata ttcccattat cctagcagct
     8881 ccaactggtc gagccgctcg tcgtatgaac gaattaaccg gtctagcaag cgcaactatt
     8941 caccgccatc ttgggttaaa cggagacaat gattaccaag caatggagga ttatttagac
     9001 tgtgatttgc tgattgttga tgaattttcc atggttgata cctggctggc caatcagcta
     9061 ttaacagcca tcaattctaa tacccagctg atcatcgtag gagatagcga ccagctgcct
     9121 tctgtcggtc ctggacaggt actagctgac ttgctaaagg ttgatcggat ccctcacatt
     9181 acccttgaca agatttttcg ccaatcagag gagtcaacca ttgttgattt agccaaccac
     9241 atacgccaag gcattcttgc tcctgatttt tgtcagaaaa aggctgatcg ctcctacttt
     9301 gaagcgcaag cgccattcat tcccggcatg atgacaaaga tcgtacaggc tgccctaaaa
     9361 agtggcatcc cagctgagga aattcaaatc ctagccccta tgtacaaagg actagcaggc
     9421 atcaacagcc tcaaccagct catgcaaaac ctcctgaatc ctctagctaa tcagacagaa
     9481 tttctcttta acgagacggc ctttcgtaag ggagacaagg tacttcacct tgtcaatgac
     9541 gctcagctta atgtcttcaa tggtgatatt ggctatatca cagacctcat tccagccaaa
     9601 tataccgaat ccaagcagga cgaaatcatc atggactttg atggcaccga gatcgtctac
     9661 ccaagaaatg aatggttaaa aatcaccctt gcctatgcca tgagcattca caaatctcaa
     9721 ggcagtgaat ttcaggtggt aatcctgcct gtcacccgtc agagtggtcg acttctgcaa
     9781 agaaacctca tctacactgc catcaccaga tcaaaaagca agctcatcat gctcggagaa
     9841 atagccgcct ttgaagaggc aatcaaaaaa gaaggtgaca agcgacacac ctatctcgta
     9901 caaaggcttc aagtggctga agctgatgac catacagcag ctgcttcagt aaaggaatca
     9961 aatcagtcta gcctatctgt aatgccagct accagcccac aaaaggaaca agagcagcct
    10021 ccttatctgc tcacccctca taatttccta gctatagacc ccatgattgg tctaaccgaa
    10081 gatgatatgt taaccttttt taagaaaaaa tcataatata ttaaaaaagt aaggcacaat
    10141 ccttattcct atgctataat atccatgtat catcttaaaa gtacaataac ataacattca
    10201 aggagactta tatgatttca tacgaacaag tacgacaagc actcagaaca tcaactatta
    10261 cgatcattat catcaatgct atcagcatgg ttatcacctt gtttggactt gctggcattt
    10321 tctttttgaa gtctcaattg gataaacctg aatttcgtgc acaattttca gctgagcagc
    10381 taaggctatt tgaggttggc atatcaccct ttactatttt tatgtcagtg attagccttg
    10441 gattggttgt tttgaccact gtgctttgtg gctttaacct ctcaaaaatc aaacaaggtt
    10501 ccactgtcag ctatgttcct tacattatag ggattgtgct ctatcttatt agtatcgtaa
    10561 gccaactatt tagccaaatt gagcctgtct caatgatcat tgtcctagct gagcttgcgc
    10621 tttacggctt tgccttttac aaggctaaaa cccttaatga aaaagacaag gacaatcccc
    10681 aaagcattga agaataagca ggccataaag gtatgataac aagacttcct gtctgccttc
    10741 aaatatggct ctttgtcagc ccactacggt tgacaaagag ccttttttaa ccactaaaaa
    10801 agcaagagga aaattgataa tgtcctcttg ctttttttgt tagttgaatg acaggtccaa
    10861 caaaatatct gtcactttat cctttagtcc ggtcattgtg actcccaata agcggattcc
    10921 tgcctgatgc tcctccaggc tatcaaaaag ctctctagcc acctgatcaa tgatcctagc
    10981 atctcttgtt aactcaggta ggctaacccg cttggtcaag gtcgtaaagt cagcataccg
    11041 aaccttcaaa acaatgatcc ttcctagttt tttattcgcc tcaagcaaat cagcgacccg
    11101 tcttgcatgt ttagaaagct ctgccttaat atcagcctcc tggtagagga gcttagcata
    11161 ggtacgctca ctgctgatgg atttgcgcat acgattaggc ttgactggag aatgactaat
    11221 gcctctggcc tttcgataaa gctcatagcc aaagcgtcca aactgatcaa tcagggtcat
    11281 ctcaggaaca cgcaaaagat cctgcccagt gtaaatcccc atctcatgca gcctttcaac
    11341 tgttcgctta ccaacgccat gaaacttttc aatcggaagc ttttctaaga atggcagagc
    11401 atcatcagga agtactaggg tcagaccatg tggcttttca aaatcactag ctagcttggc
    11461 taaaaatttg ttataagaaa caccagcaga gcaggtcaac tgcaggctat tccaaatatc
    11521 atgctgaatc agtcttgcaa tctttaaggc agacttgatg cccagcttat tggttgtcac
    11581 atctaaataa gcctcatcaa tagacacagg ctccacctga tccgtataac gcttgaaaat
    11641 ctctctgata tcatagccaa tcctacggta cttagcatga tctccagaga taaaaatagc
    11701 ctgaggacaa cgctcgtagg cctcctttga gctcattgca gagtgaatgc caaaccttct
    11761 tgcctcgtag ttacaggttg atacaacgcc ccgtccacca ctttctctag ggttcttgcc
    11821 gatcaccacc ggcttgccct ttaattcggg attatctctt tcttccaccg cagcaaaaaa
    11881 agcatccatg tcaatgtgta taatcttgcg tgaggtgtca ttaatcagcg gaaaaataag
    11941 cataggtccc tccctcctac attatactcc tttaggcttt taaagccaag gcagaggatt
    12001 gtatgacagt tttcaactgt ttcagcaaac tgtaatataa aagaatcttg tatttgtcaa
    12061 gatttttgct tgggaaatcg tttcccctat ggtaaactta gattgtaaat gtaacagatt
    12121 ggacttgtta ctagatttta aggagaaact tatggcaact gttaaaacta acgcagatgt
    12181 ttttgaaaaa gcttgggaag gctttaaggg aactgactgg aaggaaaaag cgagtatatc
    12241 tcgttttgta caggctaact atacacctta tgacggtgat gaatcattcc tagcaggtgt
    12301 tactgagcgt tcattgcaca tcaaaaaggt cattgaggag actaaagctc actacgaagc
    12361 aacacgcttc ccatacgata ctcgtccaac ctcaattgct gacattcctg ccggatttat
    12421 tgacaaggat aaggaattaa tctttggtat ccaaaacgat gagctattca aattgaactt
    12481 catgccaaag ggtggtatcc gtatggcgga aacaactctg aaggaaaacg gctatgagcc
    12541 agatcctgct gtacatgaga ttttcactaa gcatgtgaca acggttaatg acggtatttt
    12601 ccgcgcttac acgtcaaaca ttcgtcgtgc gcgccatgcc cacactgtaa ctggtctgcc
    12661 agatgcttac tcacgtggtc gtatcatcgg tgtttacgca cgtcttgccc tctacggagc
    12721 agattacttg atgcaagaaa aggtcaacga ctggaatgcc atcactgaga tcgacgaaga
    12781 atcaatccgt cttcgcgaag aaatcaacct gcaataccaa gcacttggcg aagtggttaa
    12841 gttaggtgat ctttacggtg ttgacgttcg tcgtcctgct gaaaacgtca aagaagctat
    12901 ccaatgggtt aacattgcct ttatggctgt ttgccgcgtg atcaatggtg ctgctacttc
    12961 tcttggacgt gtcccaatcg ttcttgacat ctttgctgag cgtgaccttg cacgtggaac
    13021 cttcaccgaa tcagaaattc aagaattcgt tgatgatttt gtcctcaagc ttcgtaccgt
    13081 taagtttgct cgtacaaagg cttatgacgc tctttattca ggtgacccaa ccttcatcac
    13141 aacctctatg gctggtatgg gtaatgacgg tcgtcaccgc gttacaaaga tggactaccg
    13201 cttcttaaac acacttgaca atattggtaa ctctccagag ccaaacctaa ccgttctttg
    13261 gactgataag ttaccatatg ctttccgtcg ctactgtatg cacatgagtc acaagcactc
    13321 ttcaatccaa tatgagggtg tgacaacaat ggctaaggac ggctacggtg aaatgtcatg
    13381 tatctcatgc tgtgtgtcac cacttgaccc agaaaatgaa gagcaacgtc ataacattca
    13441 gtacttcggt gctcgtgtga acgtgcttaa agcccttctt actggactta acggtggtta
    13501 cgatgatgtg cacaaggact acaaggtatt tgacatcgac cctgttactg atgatgtcct
    13561 tgactttgat actgttaagg ctaactttga aaaatcactt gattggttga ctgatactta
    13621 cgtagatgcg cttaatatca ttcactacat gactgacaag tacaactacg aagctgttca
    13681 aatggcattc ttaccatcac atcaacgtgc taacatggga tttggtatct gtggcttcgc
    13741 aaatactgtt gacaccctat cagctattaa atatgcgact gttaagccaa ttcgtgacga
    13801 agatggttac atctatgact acgaaacaat cggcgactac ccacgctggg gtgaggacga
    13861 tcctcgctca aacgaattag ctgagtggtt gattgaggct tacactacac gtctacgcag
    13921 ccacaagctt tataagaacg ctgaagcaac tgtgtcactg cttaccatca cttcaaacgt
    13981 tgcttactct aagcaaactg gtaactctcc ggttcaccgc ggtgtttacc tcaacgaaga
    14041 tggtacaact aacctatcac aacttgaatt cttctcacca ggtgctaacc catctaacaa
    14101 ggctaagggt ggctggctgc aaaacttgaa ctcacttgca agccttgact tctcatatgc
    14161 cgcagatggt atctcactaa caactcaagt atcacctcgc gcgcttggta agacacatga
    14221 cgaacaggtt gaaaaccttg ttactatcct tgatggttac tttgaaaatg gtggtcaaca
    14281 cgttaaccta aacgttatgg acttaaatga cgtttacgat aaaattatgg ctggtgaaga
    14341 cgttatcgtc cgtatctctg gatactgtgt caataccaaa taccttacac cagaacaaaa
    14401 aactgaatta actcaacgtg tcttccacga agtgctttca atggacgatg ccgctgaagc
    14461 tatttcagga aaataagcta atcttagcta gctaagagcc tgtctgttga caggttcttt
    14521 ttttatcaca catgcaatag gtacagctgt cctcagcagc tgaataacca gcagagctgg
    14581 ttgaaactac tagcaagcct atcattatca ttgtgaaaat cagacgatta accttttcat
    14641 taaaaaaaaa aaaaaacgaa actacggaga aaagctgatg aggagctctt taaggctatc
    14701 agtcaacatg ttaaactctt cttaggaagc gttaacaata actaactgct aagctaagca
    14761 attatctatt aaggagaata acaatgaaac gactaaaaac actatgcttg ttagctactg
    14821 ctataaccct aaccctagct cctatcagca caagccagac aacaacacag accgtatatg
    14881 ctagtgaaac tcatcaaaat ctttgtacga acactggtaa cggatggttt aaatgtcccg
    14941 atggacatgg agggtggact tggcattttg acgaaaatca taagtcaaat cagcagtcct
    15001 ttttgggagg attgttgggc tttgctttgt ctctatgggg agctattatt agactctttt
    15061 aagctctagc ttaactaatc ctcaaacaac aaaaataagc tcttagagaa ctaagctcta
    15121 agggcttttt gctgttctga taagtaaaaa ccaagagaca aggacatcaa aaacaagcag
    15181 gcctatcaga tataccacct gataggccca cttgtgctct cattcttatc taggactatt
    15241 tctgtcaaag gtcctatgaa tagcatcccg aagctgtcgt ctctctttga tccacaaggc
    15301 cctatcatcc ttgtcatagg ttctattggt gagaaaaatc gctgcctgct gctccttttt
    15361 attgagcatg ataaaaggcc ctgtatagcc tgtatgacta atccaatcac cctctaggct
    15421 ccaacccaaa gacctgggct tttcctgtct gctatagctt tgaaaaagtc tatccgaaaa
    15481 gctttccttc aggtaatgct caataaaccg ctctaaatcc ctgatggttg aaaaaagccc
    15541 tgctgagcct gcatggtttc ccaagacctt agccttggga tcatgtacct ctccatcaag
    15601 cacccctttg accgttggaa ctgcttctgg ccttgggcca aaggaggtct cagtcattcc
    15661 aaagggagta aaaaccatct cctgaaaaag ctcatcaaga gactttccat gaaggtgctc
    15721 tagcatgaag ccaagcaata aaaaattcac atctgtgtaa tgaaaggtct tatcgtcctt
    15781 gacctgaagc tggtgcatcg ctgctcttaa ttgctgggca ttgagctgat ctcgattggg
    15841 aatataaggg tcaagtccac tagtatgggt gagtagctgt cgcagtgtaa cctccagctt
    15901 ttgagcgtca ggataataat gccttaaagg agtatcaaga gccaaggcac cactattgat
    15961 catggctata cagacagtcg ctactccgac aaccttagag acactggcta aatcataaac
    16021 caagcctttg gtaacaggtc tttgaccatc aagggtaccg atataatgct cctgccaacc
    16081 gccacagcga aaaagggcta agctagcccc atgatataag ccttcctgaa tctgctggct
    16141 taccttttct atgacttcta atgtcatttg acaaaccaaa tttcgatctg acttgggtct
    16201 gaaagaacaa gcacccttgc ctttttatct aaataaacct gacacccttt gtcctcaagg
    16261 taggtcttta gagcaagcaa gtcatagcta tctgacacct gaaattctaa aatctccaaa
    16321 tcccatgtga catgcgggac aatcgtcaaa tcttgaccag cctccctatt aaactcaagc
    16381 gtgaccggca ggcaatcacc aaaaatagac tgataaaaag ctctggattg ctcgtcatct
    16441 aaaacattta agacaatcag atcaaagcta aactgactca gccccctaaa gtcagcttcc
    16501 ttgtcaattg caggaacatc atcgacaatg tcaagctcct tgatatcgtc ctctgcatgg
    16561 agtaagaagc gatctccctc tggtgaggtg acttcaaagg catagccttt ttttcccttg
    16621 aaaatcaaat catagtcaac gccatgagct aggagctgct caatgtcctt aggagcagtt
    16681 gttttgataa caattgtatt tactttctta gggccatcta caacgcgtgt tcttgctgct
    16741 ggagattctt caattacaaa gcgttcttgt ccttggcccc aagatgaaaa aattgatatc
    16801 gcgttttcct ctgacactag ccttaagcct agattttttt ggtaaaaggc aatattaagg
    16861 tcgcgattgt taacacgtaa tactggggtt ttaaagacaa tattgtcaaa taaagtcata
    16921 tattcctcct aatcctctgc tattatagac aaaattccaa tttttgacaa gaaattatat
    16981 gctttttaac cgcctgtcac gcgctaccaa ggcaatatag cactcacagc catcaccaga
    17041 cttactaggt ccaatcttcc ttcgtgcgct ctatcacaag cagctttcct tagcgtaact
    17101 catgcacata ttggtaaatg cgactttttc aaaatagcac atgaagtacc cctttaattt
    17161 gacttttcct taaccaaaag cgagaacctt ttttagttct cacagtagca atcacactct
    17221 tgaaatgtga tttcgctctc ctcaataaca gatgataact gaaattgccc ggattttctt
    17281 atccacgcgc aacttcaaaa gcaccttatc ttcagcatta gtaaggatac taccagctta
    17341 gctcagacca gattcagctg gctcttgctg gcaagctttt atcacaaaaa agaaggccta
    17401 agccttcttt tttacttgat ataaaggaat ttgaatgctg ctactgctgc tactgctgct
    17461 agcactgggg cagcaaccgg tacccatgag taccaccatt ttgaatcccc cttggcttgt
    17521 ccaaggactg attttggtaa gaaatggtga accaaacgag ggcctaagtc acgcgctggg
    17581 ttgagcgctg gaccagtagg accaccaaga gaggtcacaa gagtcatcac caagaaacca
    17641 atccccaagt gagctactgc aagtgagcct gtcacgtaag gagagatttg cgttgcagct
    17701 gttgtttggt catagccagc ctctaccagc ttaccaacaa gctccacacc aaagtaattc
    17761 ttggttaagg ccattgcgcc aaaaaagagg acaaaggaac caacaaactc gttcaaaaag
    17821 ccattaatgt aggctgcctt acggctgccc ttgtcaccat catcaactgc tgaaatcgtt
    17881 gagaaggatc ccaaaatatt gttagggttg tctgtctgca caaaataagg cttgtacacc
    17941 gcaacaacca ctaattggcc aaacatagcc cctagcaatt gagcaagaac atattgtaaa
    18001 acgtgtgccc aagggaacaa gcctgaaact gccaagccaa aggtaaaagc tgggttaatg
    18061 tgatttccag aaacgttacc aaacataagt gccggcatca tcacaccgag gccatagcca
    18121 aaggcaatca caagccagcc tgagcggtta ccctttgttc cctttaagtc aacattggca
    18181 actgctccat ttcccaaaat aatcaaaaat gcagtggcaa taaactctgt gatgtatttc
    18241 acagtccatg ttatttccat attctctagt ttcctccaaa tgataagtat aacagatacc
    18301 attttatcag ggatactagt tcttgtaaag cctattgtaa gatattgcct gcttaatatg
    18361 tttacagtgt tttttcacaa ttacggacaa ctaataagtc ttttttagca tgtcgcagga
    18421 tatactctga ggtcgatcca atcagcagac gctcaaaggt atttaagcca gttgctccta
    18481 ccatgatcaa atcagcctgc tccttttcag gtatgtcact agctaagagc tttttagggt
    18541 tgcctctttc gatgattttt ttaatgctgc taacgcctct gcctctagcc attttctcgt
    18601 aatagcgcaa cacctccttg gcatgctcct cttgtgtgtc aaagacataa tcactaacca
    18661 ttgcatcacc ctgataggcc ttaacatcaa taacatgagc cagcagtaag accgcatcat
    18721 tgcgaagggc aacattaatg gccttctcaa cagctaattc tgattcgtaa gagccgtcca
    18781 ccgcagccag aatccgttta tatttgctta tcatctttgt ctcctttcgt tgattagcct
    18841 ttatcaatag cctttgcttg tgtctttagg aaatacatga ctgcgcaggc agctggaatg
    18901 agccctgcca gccagaacaa ttgatgaaag gactgcacac cagacccaag aagcatatcc
    18961 ttgatgagtc ccaacagata aggtcccgca cccaagccca aatctagccc aatcatataa
    19021 gtagacatag cggtattaaa gcgatgctcc tcaaccccct tgatggaggc tgcctgtccg
    19081 caggacataa aggttccata gccaaagcct atcaaagcac ccgaaagcag atagggaagg
    19141 ctgcttgtca cactaccaag caggaaaagc cctagcgcca aaaagagata gctgggataa
    19201 agaacccact gctccccctt aacgtccatc aagcgtccca tagcaggtcg tgtgatcgta
    19261 atgatcaagg catataccac aaagaaatag gctcccaccg tcgtcaaatg aatgtctgtt
    19321 gtgtataatt tttgaaagcc tagcacagaa gcataggcaa tccccatcaa aaaggcaatc
    19381 aaggtgataa ataaggcctt tcgctcaata aagctatcaa ctgtccagga ttttgttttt
    19441 gccagctgct ctgagttgag ggcaatatct gtcacaggaa aggcaaaggc ccctagcaca
    19501 actactgcga tcaacacact gcacaaaata ataatcatcc gaaaatcaat gtgcaaatta
    19561 tccagcataa aggtcccaac aaaaggacca atcgccgccg ctaggcttgt tgatagacca
    19621 taaaaattaa tcccctctcc gcgcttgcta gctggaatat aggcagtcac aatggtattg
    19681 gttgctgttg agacaacacc atagccaaag ccattaaaca agcgcacaaa atacatcatg
    19741 ccaatcgttg gcatgaaaaa gtaggctagc gttgttagga gataaaaaat ggcgcctcct
    19801 cttagcacta agcgtcggcc aaaaacctcc aattgcttgc caaaaatcag tcgagccagc
    19861 agggttccta ggatataaat ccccgtcgcc agacctgcct cactggtctt agctcctaat
    19921 tccttagtcg caacaaaggc aatgatcacc gtaaacaagt aatagaccat atacacaata
    19981 aaatttaata ctgtgatccc tataaaatgc ttgttaaata atttgtcttc cactgaaaat
    20041 gagctcctcc ctatttcatt aacattttac aaaaaaatca gataatgccc catttcaatg
    20101 gtataatata ggtgatacta ttaaacgaca ttagcaaatg ctaagcattg ctgcagcaac
    20161 aaattatata atgataccag aaacacctct aggagaaaag cgtgaaccat caaatcttac
    20221 agcgttatat tgacagtcat aactttccta ttatcgaaaa gggctaccac aaatacctga
    20281 cctttgaaag cttagaggag gattttacgt atatcctaaa ggagggcatt gtcaagcaaa
    20341 gcgttctgtc aaaatatggc atggaattta acctcaggta cgtcacaggc cttgagatca
    20401 cctctgtgct taatactggc tattccaagg acatgagaga gccctacaat gttcgcatcg
    20461 aatctgagac tgccagcttt tataaggttc gtcattccac ctttttaagg gatattagcg
    20521 aggatatcga gctgcagggc tatgtcaagg acttttatca ctaccgcctc caaaaatcaa
    20581 tgaaaaaaat gcagtgtatg ctgacaaatg gccgtatcgg cgctatctct actcagattt
    20641 acgatttaat gacccttttt ggacgcccct tggctaatgg ccatatcctt attgatttta
    20701 tcatcacaaa tgaggagctg ggcaaattct gtggcatttc gactgccagc agtgtcagtc
    20761 gtctcctaaa gcagctcaaa aaagagggca ttattcaaat caatgaccag catatcatca
    20821 ttaccaattt agagaagcta aaggataata ttgtttttta acgatttaga aaggacgtcc
    20881 catgcgctat aatcaattgt cttacattcc caccagtcta gaaacagctg tagctgagct
    20941 tcaggccctg ggctttgctg tccagcaaga gcaagcaccc aaggagaact tcgctatttt
    21001 ccttagaaag ctattttttc attttcagga taccgattat cccttgagcc atatgattgc
    21061 aagcaaggat ctcgacctat tgaccttttt aacatctgat gcaacactga caaaagaggt
    21121 ttttgattta gtggccttac aggtccttgg ctttattcct gctgttgact ttaccgatgc
    21181 acaggacttt atacaaaaga ttggctttcc gattgttttt gacagccagc aattactact
    21241 caatttacat cagctgcttg caacccggca gaagtccggt gtgaccttga ttgatagcct
    21301 tgttagtcag ggcttgcttc ctatggataa ttgctaccac tacttcaacg gaaaagccct
    21361 agcaaccttt gataccacca gcctcattcg cgaggtggtc tatgtcgaag cgccacttga
    21421 taccgatcaa gacggacagc ttgacctcat caaggtcaac attatccgcc ccaaggccag
    21481 cactgctatc ccaagcatga tgacagccag cccttatcac caagggatta acgagaccgc
    21541 caacgataaa aagctccatc gcatggaagg tgagcttagc cctaaggctc ctcgtaggat
    21601 taccgttgag ccaactgatt ttcagccgct tgccaccaag ccctcaaggc ttcctgtcaa
    21661 tgagtgccaa gagaccttca gccatatcag ctcctacaca ctaaatgatt attttctagc
    21721 gcgtggcttt gccaatctct atgtctcagg agtgggaaca gcaggctcaa ctggctttat
    21781 gacaagtggt gactacgccc agatcgaaag ctttaaggct gttatcgatt ggctaaatgg
    21841 cagagctact gcttacacga gccacaagcg tgactatcaa atcaaggctg attggtcaaa
    21901 tggcttagtc gcaacaactg gaaaatccta tcttggtacc atgtcaacag gactggctac
    21961 aacaggtgtt gatggcttag cagtcatcat tgctgaagct gccatttctt cttggtacga
    22021 ttattatcgt gaaaatgggc tggtatgcag tcctggtggc tacccaggag aggatctcga
    22081 tgtgctgaca gagctcacct actcgcgtaa cctgctgcca ggtgattact tacgtcacaa
    22141 cgaccattat caacagctgc tgagccaaca atctcaagct ctcgagcgcc aatcaggcaa
    22201 ctacaatcaa ttttggcatg accgcaacta cctgccacag gctgatcgca tcaagtgtga
    22261 ggtcgtctac acgcatggcc tacaggactg gaatgtgaag cctagacagg tctacaatat
    22321 cttcaatgcc ctgcctgata gccttggaaa gcaccttttc ctacatcatg gtgagcatgt
    22381 ctacatgcac aactggcagt caattgattt tcgtgaggcc atgaatgccc tgctctgtca
    22441 aaaaatgcta ggacaaaata atggctttac cctaccaaca atcatctggc aggataacca
    22501 aaaagaacaa acctggaaag agctaacagc ctttggcggt cacagcaagc gtcagattgc
    22561 cctaggcgat gatcatgtct taattgacaa tcactatggc gaagaggact ttaagcgcta
    22621 tagcaaggat tttcgtgcct ttaaagctga gctttttgaa ggcaaggcaa atcaagcagt
    22681 cattgatatt ctgttagaag aggatctacc aatcaacggg caagcctgcc ttaagcttaa
    22741 gctaaaatca agtgaaaaca aggggatttt ggctgcacag ctcctagatt atggcaagaa
    22801 aaaacgcttt gctgatatac ctgctattct tgagctagac agcattgaca acgggcagca
    22861 gtttgcacgt gaagcgctca aggagcttcc cttcaaggac agcccatacc gcgttgtcac
    22921 caagggtgtc ctaaacctac agcaccgcag cgacctattg accattgagg atattccaaa
    22981 tgaccaatgg atgaccatca ccttccactt gcagccaacc atctatcata tggccaaggg
    23041 agacacccta agagtcgttc tttacacgac tgattttgag catacaatcc gcgacaatag
    23101 caactatgcc ctaaccctag atttggagca atcctatctc ctaatcccta ctgatgagga
    23161 ggaataaatc aaagcgcatc aaaaaagcct gagatcacaa tgagctgcac cccaatcgtt
    23221 agatcctttg tctaactgtt ggagtacagc tcaaagctct aggctttttt aactattttg
    23281 aaaccttttt accagcctca gcaccagaat gcaggctgta gacggactcg atatgaatca
    23341 agcctgctgc ctttggtgcg cccatcttgc cttctgccca ttccttggca gcctcaaaga
    23401 caggaccctc tgtaatgatt tccgcacgcc ctacaaagcg ataaccacgc aattgctcgc
    23461 gattgacata agcgacctca attttaccat tagcctgaat attagagcag gtttggccgc
    23521 cagtattttc attataaacc aaggtttcat cgtctaacag tctcatcgaa cgcttagggc
    23581 caatattagg attaccctca ttatctacag ttactaccat tgctaattgc tcagcaatca
    23641 tttctttcat ttcttctgtt aacatataat ctcctcttaa tcgtttctat agtcagctga
    23701 ctacgctttg attatagcac agttaagcag aaaagccgac aaaaataggt tagcttaaaa
    23761 aagttttaca gtttacttaa gattagaatg attctcgcta tctagccatc acccttgatc
    23821 acagtaaaaa ggcgattagc aagcaagcac tctttatttc ataaaatccg aatcgtcgcc
    23881 caaaaaaaat atcatcaact gatatggtca atgcctctgc aatacctctt aatttttcat
    23941 acttagctcg cctaagcttt tgcacatcct tttcatatct ggctagtgtc ctaacagaaa
    24001 tcccagttaa cgctgacagt tccttttggg tctttttttg agcaatcctc aattccttta
    24061 acgttgcttt tgacaatatt ttccctccgc ctctcatctc aggtaatatt aatgacagat
    24121 gacaagttta ttatagactt cggtttttat gaagtcaagt cttttatcgc actttcccca
    24181 cttctttttc taaatctttt gatttagctt gatttgtggt atcatatcct atatagaaat
    24241 aaaggagaat ggaaatgtcc gaaaagaaaa cattttttgc aactaattta aaatatcttc
    24301 ggctaaaaaa gaatatggaa caattagaac ttgctaacct tttaggacga aaaagctctt
    24361 cctcaatcag cgaatgagaa agaggaaagt acactccaaa atctggtctc ctgagtgaca
    24421 ttgctgccat ctttgatgtc agcctgacag acctcatgga aaaggattta acactggaaa
    24481 ataagggagt gacttatcag cttccccaaa gagatttagt aatgatttca gagcagctat
    24541 ctgaaaacaa ttataacaaa tggctggatt ttggtcagga tctcttatct catcaggata
    24601 aagaagaaaa tcacaagcca agcaaataaa gagcctcaca cgtcttattc tcatcaagtt
    24661 tcgaaaaatc acctaccact caagcacaca aaaagccttg gcagggcttc taagcataag
    24721 aaagctgtat catatcaata cctcagggac catgatatga tacagctttt tgtatctcac
    24781 ttttagacaa ggtagccaca taaagcttgc agatgaccta cctctgtatt agctaccaca
    24841 accaacagct agctagactg gcaggccctc tataagcctc agcggattat ctaagcactc
    24901 ccaacagctc caacaaaata aagacataac caataccatt atttaagata tgggctactg
    24961 ttgaaaaata gatattcttc ttccaaacat aaactaagcc gagcaaaagt cccagtccac
    25021 catacacaac gatggaagat agctcgctga aggaatagat atgaaccaag ccaaatagca
    25081 atgatgatcc caacaatcga gccagcagca tacctgtgcc tgattggccc tcaccgatta
    25141 aaatcttgcg gaaaataagc tcctcattga agggaccaat aatactcacc accagaataa
    25201 agatcactgt ctcgaagccc tcactagcat tatagcgatt agctaaaaca gctgcattgc
    25261 tgctctcttc taaaggaagg ctactgagca aaatatttgc aacataaagc actgcaaaaa
    25321 tgaccaagac ccacaaggta tttttgaccc attttgttga aaactgccgc cagtccctct
    25381 gataatctgc tcgataaagc caacagatcc caagtgcaaa aatcagcaga tgtctcccgt
    25441 aaaataaaaa ggtattcaat aaaggcggaa gctcaatcac attgctaact tgtctataaa
    25501 gatacacagc aatgatatat agcatgacca gtacagctgc acgatgacgt ttgatggtat
    25561 ccaattactc ttcctcaatt ctaataattg tcagattagc taggctatat tgccatcagc
    25621 taatcttgat cttaaatgtg actaatttac aagcactcaa cttttgaatc ggtaaagctg
    25681 acagacagcc ctaccctagc ttcaataaag ctatcttcca atagtccttg cgctcatcag
    25741 aactgtcaaa ggcctgaccc agctgagtca acagacttat ccagtcaaca tcacacagaa
    25801 caagaccatc ttaccatatc cctgccaact ataaaagccc ctaacctgac ctatttgact
    25861 actaacagca aaaaagcagc ttaaaaacac caatcagacg ccaccaagga ctcttgatca
    25921 gcgcagctcg cacagacacc tgaaaaatga cagacaagcc tcttaaaagc acctcagcaa
    25981 gctgagccaa cccttcacag aatagacaaa caacaagagc taagtcaaga cctcaagcta
    26041 gcagattaca ggcagagacg cttgcaaggc ttacccagca aaaagcaaca gactgataaa
    26101 ggattcacac cacacagcca caagtcaagc agctagccca aacaaagcac tgctcaccaa
    26161 atcctactat gctttctggt agcccttatc cattcaaaat cgtatccaag gcttcttgat
    26221 attgcttgtc tcgcaattct ctgatcacct gtgataaata ctctgcctga tacatcacaa
    26281 agtcaaaatt gaaatccaga attttggtgt tctcattcaa tgacagcctc tcctcgataa
    26341 aagcagtcat ctcagctgtt gtcacaatca agtcaaaatc agttctccaa ggcaattcag
    26401 cctctgacaa aatattaaaa cgatagacct ttgcaacaca aggactcacc tgttgcatga
    26461 ccaagctata taaaatatca atgtttttct tgttgatttc gatcactgct atggctaaag
    26521 gtggcagacc ttctctaaca agctgttcca gtcgcgtgca aagcaaatgc aaattagagc
    26581 ctgtcagccg accaacacca gaaacccgct ctgcccagct attaatcatc agctcgatac
    26641 gattggccaa gagcttactg ccttgatatt cctccgcata ataatatttt tgcgggataa
    26701 agagcgacaa atcaaacaag gtcttacgaa aataaggaat caaggtctga atacaagcct
    26761 tgtcaaaggc gatatagtgg ccaaacaatt gacgcagctc acccagcagc tcttggtaag
    26821 caggatcctc ctgaatgatc gtcaataagg ccgaagaatc ctcctcagac cattgtgtga
    26881 tcgaaaaaga gttgttaacc gtcaaataaa cgagaaaaat ataatcaatc tcgctactgg
    26941 gaaagtccat atcaagcaac aatttcccct cacgcttgaa aaagtcctcc aaatacccat
    27001 aaagcgccaa agactttaag cgtttaaaaa tcccctcctg aggaatcgca acgtcaaact
    27061 ctccacgctt ccaagatagc gacaagagca catcaaaaaa gcgaaacttc ttatccagta
    27121 acgggtgagg cgtttgttgc tttttgatcg aaaagataaa gtcatgcaca atatccagat
    27181 catggtcagt cagctcatag atgacaatcc cgtacttatc atgcaataaa gcaatcaaat
    27241 agcggatacg ccactcctca ccaacaacac tattatcctc taaggccaag ccgcactcct
    27301 caacaaaggg cttcatgtgc tgaatcagcc gataagctga cggtgtggaa ataaaatgct
    27361 ccctagcaaa gcctgagaca gatttgacct tatagcaagg tgccttgatc aagagaaatt
    27421 taagaatgtg cagccgtacc gattggcggt aaatcgtctt caaaaacggt ttgccccttt
    27481 tcaaaacggt gcagcggaca atggtgctat cccactcaaa ggcgatatct ccttggaaaa
    27541 gctcctctaa ttggtggata tagcgcttta tgttagctag gctaaagccc gtcttttgct
    27601 gaatggcgtg gaaactgatc ctttttttac caagtagtat ggtcagcagc aaagcctgat
    27661 gattaatcac tggttccaaa tactcttcaa gcaaaacact ttctcctcct taaaccattt
    27721 cgttagcgtc attatcataa caatttttac caaaaaagtg atgaaaaata tttaatatca
    27781 ggacgatttt tctgatagcc tttattataa cacaaaagct caaggcaggt aaaacgataa
    27841 agaaatcaac ttaaaactat gacacagtct catctcatat gatatagtta ttcaggtttc
    27901 ctaatggaaa acatattaac aacttaataa tggagagaag aaagttgaaa acaaaatcat
    27961 ttagaaaggt actgacaacg tcagctacct gtattgtgct ggcaacaagc tttgccggag
    28021 gaaccctaag agtctgggca gagcagcttt attatgggtg gaatgatgga acgagacaaa
    28081 gttcgccata ttttttgtac gtatcgccta aaaatgctcc aaagcgtgaa ttaaaagacg
    28141 agtatgttgt ttattgcttt aacaaaaaat tgtattggcc agatcaatgg gaatctatat
    28201 acagcaattt taatgacatc agatctccat ataacgattt acctgtatat gagaaaaaac
    28261 taggatatga tggtatattt aaacaatatg ctccagatta caaaaaagat attagtgata
    28321 tcgcaagtgc tttggtggca gttttaagta atggataccc cactaacaag tcacaactat
    28381 caactagcta ccatttaaat aatgattctt ctagaaaagt tactcaatta gccatttggt
    28441 attttagtga tagtttaaca aaagaatacc ttaaagatac gggtggttat aacttaaacg
    28501 atatggaaaa aaaagcttta gattttttaa tcagtaaagg agaggattct aagcttaaat
    28561 cagagcagag taattactca ttggatattt atgtttatca aagtggcggg catgaccata
    28621 tgaaagatta ccaaaatctt ctcggctcta ccttaattcc taaagaaccg ctaaagcctc
    28681 agctaggtgg ttttagtgga cataatggaa atggattaag cggccttgaa ggaggatcat
    28741 caggttcaca agaaactaat gaagatggta agaaaggact tataggtttc catggaggac
    28801 tctcaggaag cgagggcaaa cgagatcctt tccaggattg aagggtgagg ctggtgcacc
    28861 tgatacacct caaaagccta atgacccatt gcaaagtctt gaaggtggta actctcctat
    28921 cgtagaacaa aactatggta gtactgaggg atatcatggt caatctggca ttcttgagga
    28981 aaccgaagac actaacccac ctggtatcat tttaggtggc tcaggaaatg tcgaaacgag
    29041 atcctcatct gatggggctt ggcggtggtc tagctggcga atcaggagaa acgacaccta
    29101 aaccaggaca gactggtggt catggaccaa tcatcgagac aacagaggac acacaaaaag
    29161 gcatgtctgg gcaatctggc ggcactatcg agtcagaaaa caccaaaaag cctgaggtca
    29221 tgattggtgg gcagggacaa accatcgaaa caacagagga cacacaaaaa ggcatgtctg
    29281 ggcaatctgg cggtactatc gagtcagaag acactaaaaa acctgaggtc atgattggtg
    29341 ggcagggaca aaccatcgaa acaacagagg acacacaaaa aggcatgtct gggcaatctg
    29401 gcggtactat cgagtcagaa gacactaaaa aacctgaggt catgattggc ggtcagggac
    29461 aaatcatcga cttctctgaa aacacgcaat caggtatgtc tggacagtct ggagacacta
    29521 cggtcattga ggataccaag aagtctgaga taatcattgg tgggcaagga caaatcatcg
    29581 acttctctga ggatactcag ccgggtatgt ctgggcaatc tggaggcacc acaattgtcg
    29641 aagacaccaa gaagccgaca cctaagccta aacctgcacc tgcgccaatt gttaatgacg
    29701 aaaaacctaa caaaggcact cagctcccac agacaaatga tatgaagcaa ctcaccctaa
    29761 gcatcatcgg tgcaatgtca atgctgcttg tcctatgtct gtctctattc aagcgaccat
    29821 ctaaaaaaga ctaagcaaca ctgacaagtg atcattattg tacggacgtt tacaggcggg
    29881 ctttctgccc tcttaaaaca ccgtacaaca acaaaacggt ctaaatagaa atatccctca
    29941 agggttagac aatcgctcta gcccttgggg ctttttttga tacttataat agaagagagc
    30001 aagcagtgac actttctttt tgccctatat ctgctaacac tagcggtatg tgcagttacc
    30061 ataggctatc aactcgtcgt gcaactctag agaaaagctg atacaaaaaa caagcaccag
    30121 ccttgctgct gatgcttgct ccggacttac tgataagcct ttgtgatgtc ctagctttat
    30181 aaccatatgc ctattaccta aaggtctagt ctcctaatgg tgggctggct ggtaaaagca
    30241 aggagaaaca gctccccttt ccaagctggc tctcaacagc aatatcccca cctagttggc
    30301 gagctaactg cctagcaata gagagcccca gcccatgacc accagtcttc atattgcgag
    30361 aggcctcaac acgatacagg cgcttgaaaa tcaaaggcag gtcctctttt ttgatccctt
    30421 gcccctgatc aataacatca atgcgaatgg actgctcctg ttgataagca tgaatcgtca
    30481 aagccgtatt agcctttgaa tatttaagcg cattgctgac taaattcagc ataatccgag
    30541 acaaagcatc atatcggctg ctgatcttaa ccacctcttt tgccacctca atatgaacgg
    30601 agcgtttttc ctgctctaag gtcaattgaa attcggatag catgtcaatc aatagctttt
    30661 caagatagat gatttgaagc tgctgcttgt cgtcttgctt ttgatcattt aagctgacca
    30721 tatgcaattc ttcaactaat tgattcaaac ggttggtctg tcgtgagatg gtgtttagat
    30781 agtgcctttc ctcttccctt ggaataacgc catctaaaat cccctctaca gttgcttgaa
    30841 tagaggtcaa gggtgtctta atatcgtgcg acagctgagc aatcatcatg gatttctcat
    30901 gctcactctc actcaatgac tcaaagctga cctttagctc tgaggacatc tgattaaagg
    30961 cttcctctag atctttaaac tccaaaggac acttgatgag ctgaccacta tcaaagtttc
    31021 tttcagaaat agcctgtatc tttttcttta gccttttaag cgatgaaaaa acattactca
    31081 aaaggatcat attcacaatt cctccggcta ctgaagcaat tagagctatt actaaaatat
    31141 atgaaatatc ctcaatggta atgagcattt ggtttaaccc aacaatcagg cctgcaatag
    31201 taatcagcat agacattaaa tagccaatga caatgtacgt tcttaatcgc atgctacccc
    31261 tctaatttat aacctagtcc ccaaaccgtt ttaatggttg gtgtttgctc ggtactgtat
    31321 tttgccaagt cattgcgtag ggaatgaatg tgaacattta aggtattggt atcatctaaa
    31381 tactcctcct ccca
//
LOCUS       DARYNN010000023        31131 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.023, whole genome shotgun sequence.
ACCESSION   DARYNN010000023 DARYNN010000000
VERSION     DARYNN010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31131)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31131)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31131
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.023"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(126..1544)
                     /gene="sufB"
                     /locus_tag="TVB59_000997"
     CDS             complement(126..1544)
                     /gene="sufB"
                     /locus_tag="TVB59_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEL1009899.1"
                     /translation="MSDINETVAPQPIDLGDYQFGFHDDVEPIYSTGKGLNEAVVREL
                     SAAKDEPEWMLEFRLKSLEAFHKMPMQTWGADLSDIDFDEIIYYQKPSDKPARSWDDV
                     PDKIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKAEFEKLGIIFTDTDSALKEY
                     PELFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNEHTGQ
                     FERTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVY
                     NLVTKRARALKDATVEWIDGNLGAKTTMKYPSVYLDGPGARGTMLSIAFANTGQHQDT
                     GAKMVHNAPHTSSSIVSKSIAKSGGKVDYRGQVTFNKLSKKSVSHIECDTILMDDISK
                     SDTIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKE
                     LPMEYAVELNRLIAYEMEGSVG"
     gene            complement(1584..2021)
                     /locus_tag="TVB59_000998"
     CDS             complement(1584..2021)
                     /locus_tag="TVB59_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEL1009900.1"
                     /translation="MALSKLSSLYMAVVADHSRHPHHHGQLEGVEAVQLHNPTCGDVI
                     SLTIKFADDRIEDIAFAGDGCTISTASSSMMTDAVLGKTKEEALALADIFSNMVQGND
                     DSNQALLGEAELLAGVANFPQRIKCATLAWHALKQAIEKSDEF"
     gene            complement(2008..3234)
                     /locus_tag="TVB59_000999"
     CDS             complement(2008..3234)
                     /locus_tag="TVB59_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEL1009901.1"
                     /translation="MFDPNQIKADFKLLDQYVNDEALVYLDNAATTQKPQAVLEAMQA
                     YYQKDNANVHRGVHTLAERATRQYEASRQKVADFIGAKSSKEVIFTRGTTSSLNWVGK
                     FAEQVLKPGDEVLISIMEHHANILPWQQVCQKTGARLVYAYLKKGKLDMNDLQSKLGA
                     STKFVSITHVSNVLGCVNPIQEIARLAHARGAYFVVDAAQSVPHMAIDVQELDCDFLA
                     FSGHKLLGPTGIGVLYGKEALLNQMNPVEFGGEMIDFVYEQEATWKPLPWKLEAGTPH
                     IAGAIGLGAAISYLEAIGMDQVHAHEADLVAYTLPRLQAIAGLTVYGPDRSDERSGVL
                     AFNIDGLHPHDLATALDYEGVAVRAGHHCAQPLHKYLGLHSTVRASFYLYNTREDCDR
                     LIEAILKAKEFFNGTF"
     gene            complement(3261..4523)
                     /gene="sufD"
                     /locus_tag="TVB59_001000"
     CDS             complement(3261..4523)
                     /gene="sufD"
                     /locus_tag="TVB59_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEL1009902.1"
                     /translation="MTKEKILAFSQAHAEPTWLQELRLKAFDVMPHLELPTIERVKFH
                     RWNFGDGSLTESTALGTVPDFMALGDNPKLVQVGTQTVLEQLPMELIEKGVVFTDLAT
                     ALDEIPEQLEAHFGSALAFDEHRLAAYHTAYFNSAAVLYVPDHVEIEQPIEGIFLQDG
                     DSDVPFNKHVLIIAGKESKLTYLERFESIGDKTQAASANISVEVIAQAGSQIKFSAID
                     RLGDQVTAYISRRGRLDHAATIDWALALMNEGNVIADFDSDLIGQGSQADVKVVAASS
                     GRQVQGIDTRVTNYGKHTVGHILQHGVILERGTLTFNAIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENEVTAGHAASIGQVDPEDMYYLMSRGLDQETAERLVIRGF
                     LGAVVAEIPVPSVRQDIVTALDDKLARR"
     gene            complement(4614..5384)
                     /gene="sufC"
                     /locus_tag="TVB59_001001"
     CDS             complement(4614..5384)
                     /gene="sufC"
                     /locus_tag="TVB59_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014293969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEL1009903.1"
                     /translation="MSILEINNLHVSIEDKEILKGVNLTLRTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYQVTEGEILLDGVNILELEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAMNAGKEDRDKISVRDFITKLDEKMALLGMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPKFALLDEIDSGLDIDALKVVSKGVNEMRGQAFGAMIITHYQRLLNYITPDLVHV
                     MMDGRIVLSGDAALAIRLEKEGYAGIAEELGIDYKEEV"
     gene            complement(5505..6662)
                     /locus_tag="TVB59_001002"
     CDS             complement(5505..6662)
                     /locus_tag="TVB59_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HEL1009904.1"
                     /translation="MISFTIDDVLVLIGALLMSLLLTPIVRFLSIRVGVVDTPNARRI
                     NKVPMPTSGGLAIFTSFVIASLVLMPLASNGAHIGGQTYFQYILPVVLGGLVVTITGF
                     IDDVYELSPKLKMLGIVIGAIIVWAFTDFKFDSFKIPFGGPLLAFDPFLTFFLTVLWI
                     ISITNAINLIDGLDGLVSGVSIISLVTMAIVAYFFLPLTNFFLTLTILILIASIAGFF
                     PYNYHPAIIYLGDTGALFIGFMIGVLSLQGLKNATAVAVVTPVIILGVPIMDTIVAII
                     RRSLSGKKFYEPDKMHLHHRLLSMGFTHRGAVLVVYGIAMLFSLISLLLNVSSRIGGV
                     LLILGLLFALEVFIEGIEIWGEKRTPLFNLLKFIGNSDYRQTTLSKWKQRK"
     gene            complement(6669..7433)
                     /gene="mecA"
                     /locus_tag="TVB59_001003"
     CDS             complement(6669..7433)
                     /gene="mecA"
                     /locus_tag="TVB59_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEL1009905.1"
                     /translation="MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYAV
                     MDELGLPDNFKDSGMLSFRVTPRKDRLDVFVTKSDLNKDLNFEDLADLGDISQMTPED
                     FFRSLEQSMREKGDVNAHEKLEKIEEIMEDVVDATLAEQADSKEAAELDEPTEPLDYV
                     HYVLDFASVRDAVCFAKVIDFPIEASELYKGPRHYHMTILLDVQNKPAYFANVMYARL
                     IEHASPGTKTRAYLQEHGCQLIFDGAVEELQKIRLG"
     gene            complement(7553..8392)
                     /locus_tag="TVB59_001004"
     CDS             complement(7553..8392)
                     /locus_tag="TVB59_001004"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEL1009906.1"
                     /translation="MLFIELLKAIFFGVIEGVTEWLPISSTGHLILVQEFIRLHQDKA
                     FMEMFNIVIQLGAIIAVIVIYFERLNPFQPGKSPQQIRLTWQLWLKVAIACIPSIIIA
                     VPLDDWFDAHFNHMLPIAIALIVYGIAFLWIEKRNQTLEPRVVKLSRMSYKTAFFIGC
                     FQVLSIIPGTSRSGATILGAIILGASRTVAADFTFFLAIPTMFGYSGLKALKFFIDGN
                     HLTLSQLLVLLVASLTAFAVSLYVIKLLTDYVKKHDFTVFGRYRIVLGSLLIVYSVFK
                     SLF"
     gene            8708..10276
                     /locus_tag="TVB59_001005"
     CDS             8708..10276
                     /locus_tag="TVB59_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEL1009907.1"
                     /translation="MKKLVLSCLATLLIFLGGIGTVQADHYLRVGMEAAYSPFNWTQD
                     DSSNGAVPIEGTSQYANGYDVQIAKKIAKALNKDLLVVKTSWTGLIPALTSGKIDLIA
                     AGMSPTAERKKEIAFSNSYYTSEPVIVVASNGKYAKARSIKDFSGAKVTAQQGVWHVN
                     LLPQLEGAKLQTPMGDFSQMRQALTSGVIDGYISERPEAMTAETANKAFKMITLTKGF
                     TVSESDAAIAIGMKKGDDRLTAVNQVLDAISQKERLALMDKMIQQQPSEPKADEAKPS
                     FIKQTWSIFQSNWKQFLRGTGMTLLISMIGTITGLFIGLLIGIYRTAPKAKGKLAALA
                     QRLFGGLLNVYIEVFRGTPMIVQSMVIYYGTAQAFGISIDRTLAAIVIVSINTGAYMS
                     EIVRGGIFAVDKGQFEAATALGFTHGQTMRQIVLPQVVRNILPATGNEFVINIKDTSV
                     LNVISVVELYFSGNTVATQTYQYFQTFTIIAIIYFVLTFTVTRILRYIERRFDADTYT
                     TGANQMQVSEVPNV"
     gene            10269..11009
                     /locus_tag="TVB59_001006"
     CDS             10269..11009
                     /locus_tag="TVB59_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL1009908.1"
                     /translation="MSNPIIEIKNLKKSYGNNEVLKDISLTVNKGEVISIIGSSGSGK
                     STLLRSINLLEEPSAGEILFHGDNVLAEGYNLTHYREKLGMVFQSFNLFENLNVLENA
                     IVAQTTVLKRERSEAEKIAKENLKAVGMTEQYWQAKPKQLSGGQKQRVAIARALSVNP
                     EAMLFDEPTSALDPEMVAEVLKTMQDLAKSGLTMIIVTHEMEFARDVSDRVIFMDKGL
                     IAEEGTPKQLFEQPKQDRTKAFLQRFLS"
     gene            11357..11473
                     /locus_tag="TVB59_001007"
     CDS             11357..11473
                     /locus_tag="TVB59_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HEL1009909.1"
                     /translation="MAEKTDLASAYRRLKSPNIKTKKRALKIIHEHKRYGKK"
     gene            complement(11997..12887)
                     /locus_tag="TVB59_001008"
     CDS             complement(11997..12887)
                     /locus_tag="TVB59_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEL1009910.1"
                     /translation="MLEAILIIGFLVIVILSIMASTLYVVRQQSVAIIERFGKYQGTA
                     TSGIHIRLPFGIDRIAARVQLRLLQSEIIVETKTKDNVFVTLNVATQYRVNEQNVIDA
                     YYKLIKPEAQIRSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMSTYGYIIV
                     KTLITKVEPDAEVKQSMNEINAAQRKRVAAQELANADKIKIVTAAEAEAEKDRLHGVG
                     IAQQRKAIVDGLADSIQELKEANISLNEEQIMSILLTNQYLDTLNTFAAKGNQTLFLP
                     NTLNGVDDIRTQVLSALKTR"
     gene            complement(13150..14814)
                     /locus_tag="TVB59_001009"
     CDS             complement(13150..14814)
                     /locus_tag="TVB59_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEL1009911.1"
                     /translation="MSNITTSLFQEMVQAAATRLGKQAEYVNSLNVFPVPDGDTGTNM
                     SMTMDNGAKEVADKPASTVGEVGQILSKGLLMGARGNSGVITSQLFRGFGQSIKSKEE
                     LTGKDLAQAFQMGVEVAYKAVMKPVEGTILTVSRGAATAALKKADLTDNAIEVMQAAL
                     DGAKGALAKTPDLLPVLKEVGVVDSGGQGLVFIYEGFLSALNGDYVASEDFKATPANM
                     SEMIKAEHHKSVAGHVATEDITYGYCTEIMVALKQGPTYVKEFNYDEFQGYLSGLGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLIKIKVDNMRNQHEAQVQKIDNEPTKA
                     EAKEFGLIAVVAGDGLAEIFKAQGVDYVISGGQTMNPSTEDIVKAIEAVNAKQVIILP
                     NNKNIFMAAQSAAEVVDIPAAVVETRTIPQGFTSLLAFDPSKTLEDNVADMTASLSDV
                     VSGSVTLAVRDTTIDGLDIHENDFLGMVDGSIVVSNPDMEATLKTTFDHMIDEDSEIV
                     TIFIGEDGSSEVAQGLADYLEETYEDIEVELHQGDQPVYPYLMSVE"
     gene            complement(14814..15179)
                     /locus_tag="TVB59_001010"
     CDS             complement(14814..15179)
                     /locus_tag="TVB59_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEL1009912.1"
                     /translation="MTVKINTKDGLIELSDDVIATVVGGSATEIFGVVGMASKSALKD
                     NFQSLLRKENYAKGVVVKSTDMGISVDVYTVMSYGVKISEVSKNIQERVKFNLESQLG
                     LSADMVNVYVQNIKVVGEN"
     gene            complement(15331..15519)
                     /locus_tag="TVB59_001011"
     CDS             complement(15331..15519)
                     /locus_tag="TVB59_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEL1009913.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRTVKPNLQKVTILVDGKP
                     KKVWASARALKSGKVERI"
     gene            complement(15979..16344)
                     /locus_tag="TVB59_001012"
     CDS             complement(15979..16344)
                     /locus_tag="TVB59_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009914.1"
                     /translation="MADLSISKKSLLKGLGLLSVCLGLAVGTSRTAFAHVSTFYWNRS
                     WYLSQQNKGTDEEVEQKKKELIKKIKDSDLDGFIMGNYIDTINSHVFLYKLLHLEEYI
                     DFLIAQFDHFTPEQLEKRD"
     gene            complement(16934..17815)
                     /locus_tag="TVB59_001013"
     CDS             complement(16934..17815)
                     /locus_tag="TVB59_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEL1009915.1"
                     /translation="MPIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKQAP
                     VLIQTSMGAAKYMGGYKLAKVLIETLVESMNITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLEKAREIVKLAHAKGVSVEAEVGTIGGEEDGIIGSGELAPIEDAK
                     AMVATGIDFLAAGIGNIHGPYPENWTGLDLDHLKKLTDAVPGFPIVLHGGSGIPDDQI
                     QAAIKLGVAKVNVNTECQIAFANATRAFARDYEANVAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSANKA"
     gene            complement(18018..18103)
                     /locus_tag="TVB59_001014"
     tRNA            complement(18018..18103)
                     /locus_tag="TVB59_001014"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(18067..18069),aa:Leu,seq:aag)
     gene            complement(18158..19084)
                     /locus_tag="TVB59_001015"
     CDS             complement(18158..19084)
                     /locus_tag="TVB59_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEL1009916.1"
                     /translation="MKTIRLSKYFGILLLLLTLASVGASFYFFHVAQVREEKSFINNK
                     KRTPDNPLYPAELAFDSLTREKRSITNRGRQQVAWYLPASQDTHKTAIVVHGFTNDKE
                     DMKPYAMLFHSLGYNVLIPDNEAHGESEGDLIGYGWNDRLNLLAWIDLLVSEDKGSRI
                     SLFGLSMGAATVMMASGEQLPSQVVNIVEDCGYTSVWDELKFQAKAMYNLPAFPLLYE
                     VSALSKIRAGFSYGEASSVKQLAKNKLPVLFIHGDKDTFVPTEMVYQNYQATKGPKEL
                     MVVKGAKHAKSFETNPDQYKEKIAAFLQKYEK"
     gene            complement(19444..21057)
                     /locus_tag="TVB59_001016"
     CDS             complement(19444..21057)
                     /locus_tag="TVB59_001016"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEL1009917.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NIDPGTMSPYQHGEVYVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITDALKEKIKRAATTTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGSENVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPVE
                     QGIKNKLAQFCDVNPEAVIESRDVEHLYQIPLNLQAQSMDQIVCDHLKLDVPQADMTE
                     WSAMVDRVMNLKKTTRIALVGKYVELPDAYLSVVEALKHSGYANDTAIELDWINANDL
                     TAENAKKLLGQADGIIVPGGFGQRGTEGKIQAIRYAREHDVPMLGICLGMQLTCVEFA
                     RHVLGMEKANSFELDPDTAYPIIDIMRDQIDIEDMGGTLRLGLYPCKLKAGSRAAAAY
                     NNQEVVQRRHRHRYEFNNKFRQDFEAAGFVFSGVSPDNRLVEIVELPEKKFFVAAQYH
                     PELQSRPNRPEELYTAFVTAAVKNKNQSL"
     gene            complement(21331..21897)
                     /locus_tag="TVB59_001017"
     CDS             complement(21331..21897)
                     /locus_tag="TVB59_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEL1009918.1"
                     /translation="MKLDVFAGQEISELSMIEVARAILEERGRDNDMYFSDLVNEIQN
                     YLGKSDADIRYALPFFYTDLNTDGSFIPLGENKWGLRSWYAIDEIDEEIITLEDEEDG
                     APKRKKKRVNAFMDGDEDAIDYSADDPEDEDFVRESSDIEYDEEDPDDEKSEVESYDS
                     ELNEIIPEDDFEEVDLNEEDEEDEEEEE"
     gene            complement(22164..23447)
                     /locus_tag="TVB59_001018"
     CDS             complement(22164..23447)
                     /locus_tag="TVB59_001018"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEL1009919.1"
                     /translation="MSTSFENKATNRGVITFTISQDKIKPALDQAFNKIKKDLNAPGF
                     RKGHMPRPVFDQRFGEEVLYEEALNIVLPAAYEGAVAELELDVVAQPKIDVVSMEKCQ
                     EWTLTAEVVTKPEVKLGDYKDLTVEVEASKEVTDEEVDAKVERERNNLAELVVKEEAA
                     VEGDTVVIDFVGSVDGVEFDGGKGDNFSLELGSGQFIPGFEEQLVGAKAGDTVEVNVT
                     FPENYQAEDLAGKAAKFVATVHEVKAKEVPELDDELAKDIDEEVETLDELKAKYRKEL
                     EASKEAAYDDALEGAAIELAVENAEIVELPEEMVHDEVHRSVNEFMASMQRQGISPDM
                     YFQLTGTSQEDLHKQHEAEADKRVKTNLVIEAIAKAEGFEASDDEIEKEINDLAAEYS
                     MPVEQVRSLLSADMLKHDIVMKKAVEVITSSAKAK"
     gene            complement(23796..25205)
                     /locus_tag="TVB59_001019"
     CDS             complement(23796..25205)
                     /locus_tag="TVB59_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEL1009920.1"
                     /translation="MVTHKTKRFLKALSVTSLTLGLVLSGLAPLAPANLASAQEVQSD
                     NQPVAMKDGAILHAWCWSFNTIKENMSAIKEAGYTSIQTSPINAVIEGAGGSKDLKNW
                     YYHYQPTDYTIGNYQLGTEEEFKAMAQEADKYGINIIVDAVLNHTTSEIKAVSPKITA
                     IDNWTHGNDKIVNFNDRYQITQKSLLGLYDFNTQNRAVQEYMLNYLKRAVADGADGFR
                     YDAAKHIELPGEHNSDFWKVILNNGAKFQYGEILQGDACNEAGYGNIMGVTASNYGKL
                     IRKVLGQGYVKDWDLVNFQVHGVSEDKLVTWVESHDTYANDDEESTKLTDEDIKLGWG
                     IIAARNEGAPLFFSRPRGGGGQNGRFPGESQIGDAGSDLFKDPTIVAINQFRNRMNGQ
                     SEYIRNPGMDQGLVMIERGQKGAVITNLTIVDKDFSSTTTLADGDYKDAVTGTVYHVS
                     NHNITGHLAKKSVAVLLPA"
     gene            25656..26495
                     /locus_tag="TVB59_001020"
     CDS             25656..26495
                     /locus_tag="TVB59_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HEL1009921.1"
                     /translation="MTFILTYFNQLHLENIMVLVFSKLVSITLLLIFFVIFKKITTAL
                     FEKAIAKSFSYSRQTEARKKTLSKLLHNTLNYVFYFLLIYWILSLLGIPVSSLLAGAG
                     IAGVAIGLGAQGFLSDVVNGFFILFENQFEVGDTVTIAGIEGTISSVGIRTTQVRGFD
                     GTLHFIPNRNITVVSNKSRGNMRALIDIPLYSSTDLEHVTQIIKAVNKREVPNFPQIV
                     GQPNILGPQTNPNGQFTFRVSIFTENGQQFTIYYSFYKLYQEALLREGIKLPTASAIS
                     PLA"
     gene            complement(26591..27151)
                     /locus_tag="TVB59_001021"
     CDS             complement(26591..27151)
                     /locus_tag="TVB59_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019777568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEL1009922.1"
                     /translation="MNLKVLREEARSILLDIVERSAIKKGQLFVLGLSSSEVLGGRIG
                     QHSSLEVGEVIVKLILEELSFRGIHLAVQGCEHINRALVLEESVAEEYRLEIVNVLPS
                     LHAGGSGQLAAFKYMKQPVEVEAIAAHAGLDIGDTSIGMHVKRVQVPLVPIQRELGGA
                     HVTALASRPKLIGGVRARYQPDPIRK"
     gene            complement(27164..27637)
                     /locus_tag="TVB59_001022"
     CDS             complement(27164..27637)
                     /locus_tag="TVB59_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEL1009923.1"
                     /translation="MKQTRELALVSILTALTVVLGRFVSIATPTGFLSLLDAGVYVTA
                     FSLGKKEGMLVGGLSAFLLDLISGYPNWMLISLVAHGAQGYLAGLPGRHRFLGVGLAS
                     VIMVGLYFLAAIPMYGMGAAISEISGNAAQNTLGIGVGYLLYLGVKKQLVKVSDD"
     gene            complement(27643..28392)
                     /locus_tag="TVB59_001023"
     CDS             complement(27643..28392)
                     /locus_tag="TVB59_001023"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEL1009924.1"
                     /translation="MKNKVLTIAGSDIFSGGGLQADLAVLHQLDSFAFLAITCLTSCD
                     AKGFSIHPVATDLLAKQLSSLAAIPFQAIKVGLLPRPEIAEQVALFLELKKDIPVVLD
                     PVLVFKENQDQTVVEMTQALRSLFPLTAVITPNLREAERLAGLAINSREQMVEAAKKL
                     YEMGAKRVVIKGGNRFDQRVALDLFYDAKTLCFLEKPVLAKQNSGAGCSFAAAIAAYL
                     AKGYSPLRAVEQAKDLVFEAIQQSNDYGVVL"
     gene            complement(28382..29131)
                     /gene="truA"
                     /locus_tag="TVB59_001024"
     CDS             complement(28382..29131)
                     /gene="truA"
                     /locus_tag="TVB59_001024"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEL1009925.1"
                     /translation="MTRYKAIISYDGTLFSGFQRQSQARTVQEEIEKTLQKLTGGQGI
                     QIHGAGRTDAGVHAYGQVIHFDLEQKRDPEKLRFALDTQTPDDIDVISLEIAADDFHA
                     RYHKHFKTYEFLVDIGRPKNPMMRHYATHYPYPLDIAKMQAAIKDLVGTHDFTGFTAA
                     GTSVKNKVRTITAATLTQDPKTGFLVFTFSGNGFLYKQVRNMVGTLLKIGNGRLPIEQ
                     IRLVLESKNRQLAGPTAAGNGLYLKEIIYEE"
     gene            29318..30682
                     /locus_tag="TVB59_001025"
     CDS             29318..30682
                     /locus_tag="TVB59_001025"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEL1009926.1"
                     /translation="MKVTKFGGSSLASAQQLEKVLAIIKDDPERKIIVVSAPGKRSPT
                     DTKVTDALIAYYKAYVSDRHYHKHLEWIINRYQQICNDLTLDSKIITQIKASLEQLAR
                     LPKEHNPYLYDTFLAAGEDNNAKLVAAYLKANGLTASYLHPKDAGLIVSSEPQHARLL
                     PISYDKLEALKDHDDILVIPGFFGVTNENQICTFSRGGSDITGSIIAAGVTADSYENF
                     TDVNGIFAAHPGVVKQPQTITELTYREMRELAYAGFSVLHDEALIPAYRGKIPIVIKN
                     TNNPSHPGTTIVLEHQRKSNPVVGISGDDHFVSINLSKYLMNREIGFGRKLLQILEDL
                     NIRWEHMPTGIDDLSIVLRERELTPIKEEEILRRLVQQLEVDEVSITRNLSIIMIVGE
                     NMKSHIGVTSAATKALSEHHINIAMISQGSSEVSVMFVINSTDEKKAIRALYQTFFSP
                     DRPL"
BASE COUNT         9264 a         7451 c         5668 g         8748 t
ORIGIN      
        1 gccaagaagt cttttttatg ccttaggtat ttaaaaacta acctcttggg ttagtaccta
       61 tgtcttttaa aaagcctatc catcaggtca ccctaatgga taaggtcaat gtagctgctt
      121 cttgactagc caactgatcc ttccatttca taggcgatca agcgattcaa ttcaacagca
      181 tactccattg gtaattcctt ggtaaagggc tcaacaaacc ccatgacaat catttcagta
      241 gcttcgctct ctgacagtcc ccgactcatc aggtaataga gctgctcctc tgaaatcttt
      301 gaaacttttg cttcatgctc aagagctacc tgagagttgt gaatttcatt gaaggggata
      361 gtatctgatt ttgagatgtc gtccatcagg attgtatcac attcgatatg agagactgat
      421 ttttttgaca gcttgttaaa ggtaacctga cctcgatagt caaccttacc accacttttt
      481 gcaatagatt ttgacacaat agacgatgag gtgtgaggcg cattatgcac catcttagct
      541 cctgtatcct gatgctgacc agtattagca aaggcaatgg agagcatggt gccacgcgca
      601 cctggaccat caaggtaaac tgaagggtat ttcatggttg ttttagcacc cagattacca
      661 tcaatccact caaccgttgc gtccttgaga gcacgcgctc gcttggtcac caaattatag
      721 acattgtcag accaattttg aattgttgta tagcgcatgt aagcaccatc taaagcaaag
      781 atttcaacaa tagcagcgtg caagctgttg cttgaatagg taggtgctgt acagccctcc
      841 acataatgca cactagcgcc ctcatcaaca ataattaggg tacgctcaaa ctgaccagtg
      901 tgttcattat tgatgcggaa ataggtttgc aaaggaatgt ctaccttgac cccctttggc
      961 acataaataa aggtccctcc tgaccaaaca gcagaattca aggcggctaa tttgttgtca
     1021 gttgggggta ccagcttagc aaaatactgc ttaaatagct caggatattc ctttaaggca
     1081 gaatccgtat ccgtaaagat aatgcccagc ttttcaaact cagccttcat gttgtggtaa
     1141 accacctcag actcatattg tgctgaggcg cccgccagat aagctcgctc tgcctctgga
     1201 atgccgatgc gctcaaaggt ttccttgatt ttatctggaa catcatccca tgaacgagcc
     1261 ggcttatcag atggcttttg ataatagata atctcatcaa aatcaatatc tgaaaggtct
     1321 gcgccccagg tttgcatggg cattttatga aaggcttcaa gtgattttag gcgaaattcc
     1381 agcatccact ctggttcatc tttagcagct gataattctc tcacaactgc ttcatttagg
     1441 cccttacctg ttgagtagat aggctcaaca tcgtcatgaa agccaaattg ataatcacct
     1501 aaatcaattg gctggggggc tactgtttca tttatatcag acattttcta ttttccttta
     1561 tacgttacta aatgagagag gacttaaaac tcatcgcttt tttcaatagc ctgcttgaga
     1621 gcatgccaag ccagagttgc gcacttgata cgctgtggaa agttggcaac cccagctaat
     1681 agctcagctt cacccaagag agcctgattg ctatcgtcat ttccctgaac catatttgaa
     1741 aaaatgtcag ctagggccaa cgcttcttcc tttgtctttc caaggacagc atctgtcatc
     1801 atactagacg aagcagtcga aatcgtgcag ccatccccgg caaaggcaat atcctcaatc
     1861 ctgtcatcag caaatttgat agtaagggaa atcacatctc cacaggtagg attatgaagc
     1921 tggactgcct ctacaccctc aagctggcca tgatgatgcg ggtgtcttga atgatcagcc
     1981 acaacagcca tatataagct gcttaactta gaaagtgcca ttaaaaaact cctttgcttt
     2041 taaaatagct tctatcaagc gatcgcaatc ctccctcgta ttatagagat aaaagctagc
     2101 acgaactgtt gaatgcagtc ccaagtactt atgcaaaggc tgagcacaat gatgtcctgc
     2161 tctaactgca acgccctcat aatctaaagc cgttgcaaga tcatgcgggt gtaagccatc
     2221 tatattaaag gcaaggacgc ctgagcgttc atctgatcgg tcaggaccat ataccgtcaa
     2281 gccagcaata gcctgcagcc ttggcaaggt ataagcaact aaatcagcct catgagcatg
     2341 aacctgatcc attcctatag cctccaaata tgaaatagca gctccaagac caatagcacc
     2401 agcaatatgg ggggttcctg cctcaagctt ccaaggcaag ggcttccaag tcgcctcctg
     2461 ctcataaaca aaatcaatca tttcgccacc aaattcaact gggttcattt ggttaaggag
     2521 agcctccttg ccatacaata caccaatgcc agtcggtccc agcaacttat ggcctgaaaa
     2581 ggcaaggaaa tcacaatcta actcctgcac atcaatagcc atgtgcggta ctgactgcgc
     2641 agcgtcaacc acaaaatagg caccccgagc atgagcaagc cttgcaatct cctgaatcgg
     2701 attaacacag cctaacacgt tagagacatg ggtgatactg acaaatttgg tgctagcacc
     2761 caattttgat tgcagatcat tcatgtctag cttgcctttc ttaagataag catagacaag
     2821 ccttgcccct gttttttgac aaacctgctg ccaaggaagg atatttgcat ggtgctccat
     2881 aatcgaaatc agcacctcat cacctggctt taagacctgc tcagcaaatt ttccaaccca
     2941 atttaagctg cttgtcgtcc ctcttgtgaa aatcacttcc ttgcttgact tagccccaat
     3001 aaagtcagca accttttgac gactagcctc atactgtctt gttgctcttt ctgccagggt
     3061 atggacacct ctatgaacat tggcattatc cttttgataa taggcctgca tggcctctaa
     3121 cactgcctgt ggcttttgtg ttgtcgccgc attatctaag taaacaagag cctcatcatt
     3181 tacatattgg tcaagtagtt taaagtctgc tttgatttga ttaggatcaa acaatgataa
     3241 ctcctttctt tgactagtaa ctaacgacgt gccagcttat catctaaggc agtaacaata
     3301 tcctgacgaa ccgacggcac agggatttct gccactaccg cacctagaaa acctcgaata
     3361 acaagacgct cagcagtctc ttggtctagt cctctactca ttaaataata catgtcctca
     3421 ggatccacct gaccgataga ggcggcatgg cctgctgtta cctcattttc atcaatcagg
     3481 agaataggat tggcatcaga gcgagcctga tctgacagca ttaggacacg actttcttgt
     3541 tgggcatcag caccctttgc tcccttaatg atatgaccga tagcattaaa tgtcaatgtc
     3601 ccgcgctcca agataacccc atgctgtaaa atatgcccaa ccgtatgttt tccataattg
     3661 gttactcggg tatcaatccc ctgaacttga cgaccacttg aagcagcaac caccttcaca
     3721 tcagcctgtg agccttgacc gatcaaatca ctatcaaagt cagcaatgac attgccctca
     3781 ttcatcagag caagcgccca atcaatagtc gcagcatgat ctaagcggcc tctgcgactg
     3841 atataggctg tcacctgatc acccaggcga tcaatcgccg aaaacttaat ctgacttccc
     3901 gcctgagcaa tgacctcaac actaatattg gcactagctg cttgggtctt gtctcctata
     3961 gactcaaagc gctcaaggta ggtcagctta ctttctttac ctgcaatgat gagcacatgc
     4021 ttgttaaagg ggacatcact atcaccatct tgcaagaaga tcccttcaat tggctgctca
     4081 atctcaacat gatctggaac atatagcaca gccgcactgt taaaataagc cgtatgatag
     4141 gccgccagtc tatgctcatc aaaggctaag gcagaaccaa aatgagcctc aagctgctcg
     4201 ggaatctcat ctagagctgt agcaaggtct gtaaaaacaa ctcccttttc gatcaattcc
     4261 ataggaagct gctcaagaac cgtctgtgtt ccgacctgaa ccagcttagg attatcaccc
     4321 aaggccataa aatctggaac agttcctaaa gcagtgcttt ctgtcaggct accatcacca
     4381 aagttccaac ggtgaaattt aacccgttca atagtaggca gctctaaatg tggcatcaca
     4441 tcaaaggcct ttaagcgcag ctcttgcagc caagtaggct cagcatgcgc ttgagaaaag
     4501 gccaatatct tttcttttgt catctatcct tccttttttc tggtaagctt ttcaatcatc
     4561 agcaaacata ctaatcagca cagctatggc gaagccttag acagccttgc agcttagacc
     4621 tcttctttat agtcaatgcc tagctcctca gcaatgcctg catagccttc tttttcgagt
     4681 cgtatagcaa gtgcagcatc ccctgatagg actatccgac catccatcat gacatgcacc
     4741 aagtccggag tgatgtaatt aagcaagcgc tggtaatggg taataatcat cgcaccaaat
     4801 gcctgaccac gcatctcatt aacccctttt gacaccacct ttagggcatc aatatcaagc
     4861 cctgagtcaa tctcatctaa cagcgcaaac ttaggctcta gcatgagcaa ttgcagaatt
     4921 tcatttcttt ttttctcacc gccagaaaag ccttcattga ggtagcgctc tgccatttcc
     4981 tccttcatgc caagcagggc catcttctca tctagcttgg taatgaagtc acgaacagaa
     5041 atcttatccc tgtcctcttt ccctgcattc atagcggctc gcataaattc ggcattggta
     5101 atccctggaa tctcagacgg gtattgcatc gctagaaaaa gtcccagtct agcacgctca
     5161 tcaacctcta gctccagaat attgacacca tctagtaaaa tctcaccctc tgtcacttga
     5221 tagttgggat tgcccataat cgctgctgac agtgttgatt ttcctgttcc atttggcccc
     5281 atgatagcag caatttcacc tgtccttagg gttagattga ccccctttaa aatctcttta
     5341 tcctctatcg aaacatgcaa attgttgatt tcaagaattg acattgtata cctcatcatt
     5401 tctattaggc tctttcagta tcttctttcc tgaaaatagc ctaatgcttt cattatcttc
     5461 attataacaa aaaaagcctc agcaggcttt ttacttgtct gaaatcattt cctttgcttc
     5521 cattttgaaa gcgtcgtctg acggtaatcg ctattaccga taaacttcaa gaggttgaat
     5581 aggggcgttc gtttttctcc ccagatttca ataccttcaa taaagacctc tagggcaaat
     5641 aagagtccca agataagcaa gaccccacca atacgactag agacattcaa caaaagagag
     5701 atcaaggaaa agagcatagc aataccgtaa acaaccagca ctgcaccgcg atgtgtaaac
     5761 cccattgaca agagacggtg atgcaggtgc atcttatcag gctcgtaaaa tttctttcca
     5821 gacaggcttc gacgaataat cgccacaatc gtatccataa ttggaacacc taaaataata
     5881 accggtgtaa caacggctac cgcagttgca tttttcaagc cctgcaatga taacacacca
     5941 atcataaagc cgataaaaag cgctcccgta tccccaagat aaataatagc cgggtgatag
     6001 ttatagggaa aaaagccagc aatagatgca atcaggatta aaatcgtcag ggttaaaaag
     6061 aaatttgtca atggcaaaaa gaaataagct acaatagcca ttgttactaa gctaataatc
     6121 gaaacaccac tgactagacc atctaagcca tcaataagat taatcgcatt ggtaattgag
     6181 ataatccaaa gaacggttaa aaagaaggtc aagaaaggat caaaagccag caagggtcca
     6241 ccaaaaggaa tcttaaagct atcaaattta aagtcagtaa aggcccagac aataatggca
     6301 ccaatgacaa ttcccagcat tttcagctta ggacttagct catacacatc gtctataaag
     6361 cctgttatgg taaccaccaa gcctcctaag acaactggca aaatatactg aaaataggtt
     6421 tgcccgccaa tatgagcacc atttgatgcc agaggcatca gtaccagact cgcaatcaca
     6481 aaggaagtaa agatagccaa gcctccacta gtcggcatgg gaaccttatt aatccgtcta
     6541 gcatttggag tatctaccac accgactcta atgcttagaa aacgtacaat tggcgttaat
     6601 aaaagtgaca tcagcaaggc accaattaaa accaagacat catctatcgt gaacgaaatc
     6661 atcataccct accccaacct gattttttgc agctcctcaa cagcaccatc aaaaatgagc
     6721 tgacaaccat gctcctgcaa ataagctctt gtttttgttc caggactagc atgctcaatc
     6781 aatctggcat acatcacgtt ggcaaagtag gcaggcttgt tttgcacatc aagtaaaatc
     6841 gtcatgtgat aatgacgagg acccttatac aattcagaag cctcgatcgg aaaatcaatc
     6901 accttagcaa agcaaacagc gtctcgaaca gaagcaaaat caagaacata gtgaacataa
     6961 tcaagtggct ctgtcggctc atcaagctca gcagcttcct tactatctgc ttgctcagcc
     7021 aaggtagcat caaccacgtc ctccatgatc tcctcgattt tttcaagctt ttcatgggca
     7081 ttgacatcac ccttttcacg catagactgc tccaagcttc tgaaaaaatc ctctggagtc
     7141 atttgagaaa tatcacctag gtctgccaaa tcctcaaaat taaggtcctt attgaggtct
     7201 gatttggtca caaaaacatc taagcgatcc tttcttggag tcactcgaaa gctaagcata
     7261 ccactgtcct taaaattgtc cggaaggccc aactcgtcca tgacagcata aaagaactcc
     7321 tctgtctttt cttgagggat caagaagtcc ttgagctcca tccccctttc ttctaaatcg
     7381 tccatactaa ttgttatttt tagcgttgtc tcgctaattt gtttcatttc cattgtaaaa
     7441 tacctcgcag gcgtagtcat tttattatac tagaaatact atgatttcgc aatttatgac
     7501 tagccttaca gcaagtaaaa gcagccttcc taggaaaact gcctgacgat ttctaaaaaa
     7561 gtgacttaaa tacactgtag acaatcaata agcttcccaa cacaatccgg taccgcccaa
     7621 agactgtaaa atcatgcttt ttaacataat ctgttaacaa tttgatcaca tacaaactga
     7681 ctgcaaaggc tgttaggctg gcaactaaaa gcactaatag ctgcgagagg gtcaaatggt
     7741 tgccatcaat aaaaaacttc aaagctttta ggccactata gccaaacatc gtcggaatgg
     7801 ccaaaaagaa ggtaaagtcc gcagcaactg tcctgcttgc tccaagaata atcgccccta
     7861 aaatcgttgc tcccgaacga ctggtcccag gaataatgct aagcacctga aagcagccaa
     7921 taaagaaggc tgttttatag gacatacgag atagcttgac gactcgcggc tcaagtgtct
     7981 gatttctctt ttcaatccat aaaaaggcta tcccataaac aatcaatgca atagcaatag
     8041 gaagcatatg attaaaatga gcgtcaaacc aatcatcaag tggtactgca atgataatag
     8101 acggaataca agcaatagca accttaagcc acagctgcca ggttagcctg atttgctgtg
     8161 ggctcttgcc aggctgaaaa gggttcaagc gttcaaagta aataacaata accgcaataa
     8221 tcgctcccag ctgaataaca atattaaaca tctccataaa ggccttatcc tgatgaagtc
     8281 tgataaattc ctgaaccaaa atcagatgtc cagtactgga aataggcagc cactcagtaa
     8341 ctccctcaat aacaccaaag aagatggcct tcagcaattc aataaataac atgttccctc
     8401 cttctaacaa agactctcat atctagcccg tcctaaaaga acaccacttc ctcctccatt
     8461 gccagcggag aagccgcaac cacagtcacc aagcaacagc aatggggtat tgcttttttt
     8521 gcttgttcat attgtaccat aaatgacacc gttaataaat cagtgacttc ataagaaaaa
     8581 gcttattttt aatcatttct tcacttgttt tatgaataaa taatcacctc ttttaaccaa
     8641 tgtattgaaa tagcttgtaa attactatag aatagtatta aacacgtttt taaaaaagga
     8701 gacctatatg aaaaagctag tccttagctg cttggccacc ttacttattt ttcttggagg
     8761 aataggtact gtgcaagcag atcactattt acgagttggt atggaggcgg cttactctcc
     8821 atttaactgg actcaagatg attcgtcaaa tggcgctgtt cctatcgaag gaaccagcca
     8881 atacgccaat ggctatgatg tgcaaatcgc taaaaaaatt gcaaaagcat taaacaaaga
     8941 cttattggtt gtgaaaacct cgtggacagg tcttattccg gctctgacct caggtaagat
     9001 tgatttaatt gcagctggta tgagcccaac agcagagcgc aaaaaagaaa ttgccttttc
     9061 taacagctac tacaccagcg agccagtcat tgttgtcgcc tcaaatggta agtatgccaa
     9121 ggctcgttct atcaaagatt tttcaggtgc taaggtaact gctcaacagg gcgtgtggca
     9181 tgtcaacctg ctaccacagc tagagggggc aaagcttcaa acaccaatgg gagatttttc
     9241 tcaaatgcgc caggctctaa cctctggagt gattgatggc tatatctccg agcgccctga
     9301 ggcaatgaca gccgagactg ccaacaaagc ctttaaaatg atcactctaa caaaaggatt
     9361 taccgtttca gagtcagacg ctgccattgc cattggcatg aaaaaaggag acgaccgcct
     9421 tacagcagtc aatcaagtgc ttgatgccat ttctcaaaag gaacgccttg ccttgatgga
     9481 caagatgatc caacagcagc caagcgagcc caaagctgat gaagcaaagc cctcctttat
     9541 caagcaaacc tggtcaatct ttcaaagcaa ctggaagcag ttccttcgcg ggacaggcat
     9601 gaccctcctg atttcgatga ttggtactat cacaggactt ttcatcggtc tcttgattgg
     9661 tatttaccgt acagcaccaa aggctaaagg caaattggca gcgctagctc aaaggctctt
     9721 tggtggacta ctcaacgtct atatcgaagt ctttcgtggg acgccaatga ttgttcaatc
     9781 aatggtgatc tactacggca ctgcacaggc ctttggcatt tccattgacc gcacactagc
     9841 agctatcgtt attgtctcaa tcaacacagg tgcttacatg agtgaaattg tccgaggcgg
     9901 tatctttgca gttgacaaag ggcagtttga agcagcaaca gcccttggct ttactcatgg
     9961 gcaaaccatg cgtcagattg tccttcctca ggtggttcgt aatatcctac ctgctactgg
    10021 taatgagttt gtcatcaata tcaaggatac ctctgtcttg aatgtcattt cagtggttga
    10081 gctatatttc tcaggaaata cagtggctac tcagacttat caatacttcc aaacctttac
    10141 cattatcgct attatttact tcgtcctaac ctttacggta acgcgtatcc ttcgctatat
    10201 cgaacgtcgc ttcgatgctg atacttacac taccggagca aaccaaatgc aagtttcgga
    10261 ggtcccaaat gtctaatccc attattgaaa ttaaaaacct aaaaaaatct tacggcaaca
    10321 atgaggtcct aaaggacatc tcgctaaccg tcaataaagg agaggtgatt tcaatcatcg
    10381 gttcatctgg atcaggcaaa tcaaccctcc tacgctcaat caacctatta gaagagccta
    10441 gcgccggaga aattctcttt catggtgaca atgtgcttgc agaaggctac aacctgaccc
    10501 attaccgtga aaaattgggc atggttttcc agtccttcaa tctctttgaa aatcttaacg
    10561 ttttagaaaa tgcaatcgta gctcaaacaa ctgtcctcaa gagagaacga tcagaggctg
    10621 aaaaaatcgc caaggaaaat ctcaaggcag ttggcatgac cgagcaatac tggcaagcca
    10681 agcctaagca gctatcaggc ggacaaaagc aacgtgttgc tatcgcccgc gccctatctg
    10741 ttaaccctga agccatgctg tttgatgagc caacatcagc tcttgaccca gaaatggtcg
    10801 cagaggtctt aaaaaccatg caagatctgg ctaaatcagg cttgaccatg attattgtca
    10861 ctcacgaaat ggagtttgca agagatgttt ctgaccgtgt cattttcatg gataaggggc
    10921 tcattgcaga agaaggcacg ccaaagcagc tctttgagca gccaaagcag gaccgaacca
    10981 aagcattttt acagcgcttt ttgtcataag cctaaaagcc agtctaacca taggtgttag
    11041 attggctttt tttgataagt cacatctgct aagcagcata atgatcatat agactacttt
    11101 agatcaaaga aaagacctat tataggacaa tttccctcaa caggcacaga taataaacct
    11161 ccttttgaag gttgtgctgc tactttttca aagctgctaa ggcaactggt ctacaaaaat
    11221 catttctcaa atgagacggt aactgttaag cttgatctct attctaaaat ttcaacacaa
    11281 aatactttac tggttaataa ctttgtgcta tactgtcttt attaacgtta ataatatatt
    11341 ttagtaggag gatagcatgg ccgaaaaaac tgacctcgcg tcagcttaca gaagactaaa
    11401 aagcccaaat attaaaacta aaaaacgtgc tctgaagatt attcacgagc acaaacgtta
    11461 cggtaaaaaa tagtattcta tttttatctc tccaaattta agtcagataa aaaatgatta
    11521 ggacaccatc cctccgtctt aatcattttt tgatggccaa gaaaagaaag ctttaagcat
    11581 tgttaaccat caacaagctg aggacacaca catctgatag agctgccaat agtagcagtt
    11641 aggaaatgct acactcagct tttaggtcca tgcttcagca ttttcaagca accggatacc
    11701 aagaaaacta accttttagc acagcacaaa gcggcacttg aactcacttt gttccctcat
    11761 ttgctctctt agcggctaag cttcaaaggt gattgaaaca acccattgca attggtctag
    11821 cttccaagct gtttgagcct gtgattcttg ctagcatttc agacatagca acatttttca
    11881 atagccatta tgcttaagac aatagtgaaa taaagacgac tgccttactt ttcaagaaca
    11941 ttgacgagcc atcatacaaa aagcaagctg atgctgacca gcttgcttaa tatatattat
    12001 cttgttttta aggctgatag cacctgagtg cgaatatcat caacaccatt tagagtattt
    12061 ggtaggaaaa gggtctgatt accctttgca gcaaaggtat tgagggtatc taagtactgg
    12121 ttggtcagaa gaattgacat gatctgctct tcattcagtg aaatattagc ctccttcaat
    12181 tcctgaatag aatcagccaa gccatcaaca atagccttac gctgctgtgc aataccaaca
    12241 ccatgcaggc gatccttttc ggcttccgct tctgctgcag ttacaatttt aatcttatca
    12301 gcattagcca attcctgtgc tgccacacgc ttacgctgag cagcattaat ttcattcata
    12361 gactgcttga cttcagcgtc tggctcaacc tttgtaatca aggtctttac aataatatag
    12421 ccataggttg acatttcttc tgctacctga tgctgcacct ccaaggcaat ttcatctttt
    12481 ttctcaaaca attcatctaa ggttagcttt ggaacagaag agcgcaaggc atcttcaata
    12541 taagacctaa tttgagcctc tggcttgatc aatttgtaat aagcatctat cacattttgc
    12601 tcattcacac gatattgagt cgcaacattt agcgtcacaa aaacattgtc cttggtcttt
    12661 gtttcaacaa taatctctga ctgcagcaaa cgcaattgca cacgcgcagc aatgcggtca
    12721 atcccaaagg gcaatcgaat atgaatacca ctagtagctg taccttgata tttaccaaag
    12781 cgctctataa tagcaacaga ttgctggcgc accacataca gcgtgcttgc cataatggat
    12841 aatatcacaa tcaccagaaa tccaataatc aaaatagctt ctaacatgtt aatctcctcc
    12901 ttataaagcc ctagctggat agctatacgg ctttttatga ttgcctcatt gttataagac
    12961 aattataaaa catttttgtc ttttgtcaat aaaaatctca acgtctatca gccggcttta
    13021 cagctgctag agaccactaa aagtctacac ctgacgacag gctgcaatca ttgcttctta
    13081 atagtcaagt cttccttcca aagacaaaag gagctaagcc ttgcctaact cctctctttg
    13141 ttctattcat tattcaacac tcataaggta tggatacaca ggctgatctc cctgatgcaa
    13201 ctcaacctct atatcctcat atgtttcctc gaggtaatca gcaagacctt gagccacttc
    13261 actgctgcca tcctcaccaa tgaagatcgt aacgatttcg ctgtcctcat caatcatgtg
    13321 atcaaaggta gtctttaggg tagcttccat gtctggattt gacactacaa tgctgccatc
    13381 gaccattcct aaaaagtcat tttcatgaat atcaaggcca tcaatcgttg tatcgcgcac
    13441 agccagagtc acacttccac taaccacatc agacaggctt gctgtcatat cagctacatt
    13501 atcctccaaa gtttttgaag gatcaaaggc cagcaggctc gtaaagcctt gtggaattgt
    13561 acgtgtctcc acaacagccg caggaatatc cacaacctcg gctgctgatt gggctgccat
    13621 gaagatgttt ttattgtttg gtaagataat cacctgctta gcattgacag cttcgatagc
    13681 cttaacaata tcctcagtag atggattcat ggtttgtcca cctgagataa cgtagtcaac
    13741 cccctgtgcc ttaaaaatct ctgccaggcc atcacctgca acaacagcaa tcaggccaaa
    13801 ctcttttgcc tctgccttag taggctcatt gtctattttt tgtacctgtg cctcatgctg
    13861 attgcgcatg ttatctactt taattttgat cagtgagccg tacttcagac cctcttgcat
    13921 cactagccct ggatcctctg tatggacgtg aaccttaacg atctcatcat catttactac
    13981 taaaagcgaa tcaccaagcc cactcaaata gccctgaaat tcatcataat taaattcttt
    14041 aacataggta ggaccctgct ttagagcaac cataatctca gtacaatagc cataggtaat
    14101 atcctcggta gcaacatgac ctgcaactga tttgtggtgc tcagccttaa tcatctcaga
    14161 catattggca ggagtggcct taaagtcctc agaagctaca taatcaccat ttaaggcaga
    14221 caagaagccc tcgtaaataa agacaagacc ttgacctcct gagtcaacaa caccaacctc
    14281 ttttaaaact ggcagcaggt ctggtgtttt tgcaagggct ccttttgcac catctagcgc
    14341 tgcttgcatc acctcaatgg cattatcagt aaggtctgcc tttttcaagg ctgctgttgc
    14401 tgcaccacga gaaacggtca aaatagtccc ctcaacaggc ttcatcaccg ccttgtaggc
    14461 aacctcaact cccatctgaa aggcctgagc taaatcctta cctgtcagct cctcttttga
    14521 cttgatactt tggccaaagc cacgaaaaag ctgcgaggta ataacaccag aattgccacg
    14581 cgcccccatc aagagaccct tggataggat ctgcccaacc tcaccaaccg ttgaagccgg
    14641 cttatcagca acctctttag caccattatc cattgtcatg ctcatattag tccctgtatc
    14701 accatctggt acaggaaaaa cgtttaagga attgacatat tctgcttgtt taccaagacg
    14761 agttgctgcc gcttggacca tttcttggaa taagcttgtt gtaatatttg acactaattt
    14821 tctcctacaa ctttaatatt ttgcacgtaa acattcacca tatccgcaga aagcccaagc
    14881 tgactctcaa ggttaaattt cacacgctcc tgaatatttt tggatacctc actaatttta
    14941 acaccgtagc tcataacagt atagacatca actgaaatac ccatgtccgt tgacttaaca
    15001 actacaccct tagcataatt ttctttgcga agtagcgatt gaaagttatc ttttagagca
    15061 cttttactag ccataccaac aacgccaaaa atttccgttg ctgaacctcc aacgacagtt
    15121 gcaataacgt catcagatag ctcaattaga ccatcttttg tattaatttt tacagtcata
    15181 gttactacct caaaaagttt ttatcagctt attttatcat aattcaaggt caatgtaaaa
    15241 agatataagc gaagaaaggt cacctctatc atgcttttct aagctttttc tgaaaacgac
    15301 taagaaaaaa agccctaagg cttatttcga ttagatgcgt tctactttac cagatttaag
    15361 cgcacgagct gaagcccaaa ctttttttgg tttaccatca acaaggatag taactttttg
    15421 aagatttggt ttaacagtac gttttgtttg gttcatagcg tgtgaacggt tgttaccaga
    15481 tacagtctta cgacctgtga aataacatac tttagccatt gtaatctatt tcctcctagg
    15541 tagaatatgt ttacggatgt gctagcacca catacttacc tagtctatca caactcttac
    15601 cttttggcaa gctatttttt acatctgcag gccttagcca ctaagcagca aaatgtccct
    15661 cttaatagct aagcactcac ttgctcctct cctataaata ggtctataag aatcaataat
    15721 accctatcta tcacaaatgt ctaagggctg ctgtcagctc gaaagccttc tcttagaacg
    15781 ctaaaactac tctaagaaat agaggttatt taacaggctt tgctgtagtt gcctagctga
    15841 aatcctataa gcatgcacta aaaaagacta aacaagacat cacacaacca cattagtagg
    15901 gagattagcc tgaggagtgc ttcttgttta gtcttttatc ctcttgaaag ccttgatcag
    15961 tatcgtgatt gctgatttct aatcacgctt ctctaactgc tcaggtgtga agtggtcaaa
    16021 ctgggcaatt aaaaaatcaa tatactcttc aaggtgtaaa agcttataga gaaaaacgtg
    16081 gctattaatg gtatcaatat aattacccat aataaagcca tctaaatcag aatctttaat
    16141 cttcttgatt aattccttct ttttttgttc aacctcttca tcagtgcctt tattttgctg
    16201 agacaggtac caggacctat tccaataaaa ggttgataca tgcgcaaaag ctgtccggct
    16261 agtaccgact gctaaaccaa gacaaacaga tagtagtcca aggcccttta aaagagactt
    16321 ttttgaaata cttagatctg ccatagcgag tcctcctttt tatttttcta accaaaccat
    16381 actaaaatat aactatattg taaaataaaa agtattgtat tagaaataag taaaaataaa
    16441 gctatgaata gttgacctaa ctaaacccaa caaataagat gctacatgac aaaattcctt
    16501 ttattctcac cacctgtgat ctcatcaaaa gctctctaaa ccagagaggc atagacagct
    16561 accgaatgaa gccttagtaa tagctgtctc agctcacctt aaactaatag ggtcgataaa
    16621 taaggagaca tttgcgcagc agaagctgat agtgtcaaag gttctacttc agcaagcata
    16681 tcatgagtca cctatttcag cacaggcttg gtaatgtttg gatagtacaa agcgtttttc
    16741 tcaagaacgt tcaagatcct tccagtcata gcagagcagc ccttaccaca gacatctgct
    16801 agcacacacc tcaaaaacaa agacataatc gctcaagtag ggctattctt tatcggcaag
    16861 gggattaggc gaaggaacta taaaaaggcc tatccttgcg gataaaccct gatttaatca
    16921 cgtttagcag tcattaagcc ttgtttgctg agccaaagac atcaatacgt tcttcaacag
    16981 aagcctggat cgccttaaca ccatctgcca agaatttacg tgggtcaaag agttttttct
    17041 tatcgtattc tgcaacgttt gcttcgtaat cacgcgcaaa ggcacgagta gcgttagcaa
    17101 atgcaatttg acactctgta ttaacattaa cctttgcaac accaagcttg atagctgctt
    17161 gaatttggtc atcaggaata cctgaaccac catgaagcac gattgggaag cctggtacag
    17221 catcagtcaa tttcttcaag tgatctagat caagaccagt ccagttttct gggtatgggc
    17281 catggatatt accaatacct gcagccaaga agtcaattcc tgtagcaacc attgccttag
    17341 cgtcttcaat cggagcaagc tcaccactac cgatgatacc gtcttcttca ccaccaattg
    17401 tacctacctc agcttcaact gaaacaccct tagcatgtgc tagcttaaca atttcacgtg
    17461 ctttctcaag gttttcttca actggaaggt gtgaaccgtc aaacatgatt gaagtgtaac
    17521 caacctcgat acattcaaga gcatcttcat agtgaccatg atcaagatgg atcgcaaccg
    17581 gtacagtgat gttcattgat tctacaagag tttcgataag aaccttagct agcttgtagc
    17641 cacccatgta tttagctgca cccattgagg tttggataag aacaggagct tgtttagctt
    17701 ctgctgcacg caggatcgct tgagtccatt caaggttgtt tgtgttaaat ccaccaacag
    17761 catagccgtt atcacgtgct gcttggacaa atttttctgc tgaaacgatt ggcattttaa
    17821 taagcctcct cttatatttt gggttaaccc catttacatt gttcatttta gcacaatttt
    17881 caagaaattt ccagcccctc atcagcttaa agcgttttct cgattcatct tatcacaggc
    17941 tcacaattga gcatttggct agcagcagtc ttttcaggaa ataaaaaaaa agatgaatcc
    18001 aagattcacc tctgcgatgc ggagagtggg acttgaaccc acacgaccta aagcggtcac
    18061 aggatcctta gtcctgcgcg tctgccaatt ccgccatccc cgcttgctct ttagcaacat
    18121 ataaaattat atcagctggg agctttactg tcaatactta tttctcatat ttttgcaaaa
    18181 aggccgcaat cttttccttg tactggtcgg gattggtctc aaaggacttg gcatgcttag
    18241 cccccttaac aaccattagc tctttaggac cttttgttgc ctgatagttt tgatagacca
    18301 tctctgtcgg gacaaaggta tccttgtcgc catgaataaa gaggactggc agcttatttt
    18361 tggccaattg cttcaccgag ctagcctcac catagctaaa gccggcacga attttagaga
    18421 gggctgaaac ctcatacagc aagggaaagg ctggtagatt gtacatggcc ttagcttgga
    18481 atttcaattc gtcccaaaca ctagtatagc cacaatcctc aacaatattg acaacctgac
    18541 taggtagctg ctcaccgctt gccatcataa cggttgcggc acccatggat aagccaaata
    18601 agctaatgcg actgccttta tcctcgctaa cgagcaaatc aatccaggca agtaggttca
    18661 agcgatcatt ccagccatag ccaatcaagt caccctcact ctcaccatga gcctcattat
    18721 ctggtatcag cacattgtag cctaggctgt gaaaaagcat ggcatagggc ttcatgtcct
    18781 ctttatcatt tgtaaagcca tgaacgacaa tagctgtctt atgagtatcc tgcgaggcag
    18841 gcaaatacca tgcaacctgt tgacgtcctc tgttagtgat actgcgtttt tcacgcgtca
    18901 agctgtcaaa agctagctct gctgggtaca aaggattgtc tggggttcgt tttttattgt
    18961 tgataaatga cttttcctca cgcacctgag caacatggaa gaaataaaag ctagctccca
    19021 cactagccag ggtcaacaag agcagtaaaa tgccaaaata ctttgataat cgaatggttt
    19081 tcataccgac tattctacaa gaaaatatgg aaaaaagaaa gctttatgct aaaaataacc
    19141 gatacctttt tactgccttc ttaaggccaa atctcaagcc agccagtagc taaagcgttt
    19201 tcgcaggaat tgaagctcaa tagtttaaag aatatacaag ctaccttcaa aatagctttg
    19261 accagatcaa gaggaagtcc gctgacagca tttgataaga ggtaaaatgg tgctttttgc
    19321 tatattaaaa gtggctgatg tcatcatctc atcagccact caaagactta ataagcctat
    19381 caaagctgct aactctcagc acctaaataa ggctcaagga tagcctctta cgtcatacta
    19441 gacttaaagg ctttggtttt tatttttcac tgctgctgta acaaaggcag tgtatagctc
    19501 ttcaggacga ttaggacggc tttgcagctc tggatggtat tgggctgcca caaagaattt
    19561 cttctctggt aattctacaa tctctaccaa acgattgtcc ggcgaaacac ctgagaaaac
    19621 aaagcctgct gcttcaaagt cctgacggaa tttattgtta aattcgtaac ggtggcggtg
    19681 acggcgctgc accacctctt ggttattgta ggctgctgca gctcttgagc cagcttttag
    19741 cttacatggg tatagcccca gacgtaatgt tcctcccatg tcctcaatat caatttgatc
    19801 acgcataata tcaatgattg gataggcagt atctggatcc agctcaaacg aattggcctt
    19861 ttccatgcct aggacatgac gagcaaactc aacacaggtt aattgcatgc ctaagcaaat
    19921 gcccagcatc ggcacatcat gctcacgcgc atagcgaatg gcttgaattt ttccttctgt
    19981 tccacgctga ccaaagccgc caggaacgat aatgccatca gcctgcccaa gcagcttctt
    20041 agcgttttca gctgtcaggt cattagcatt aatccaatca agctcaatag cagtgtcatt
    20101 agcatagcca gaatgcttta gggcttccac aacagacaaa tacgcatctg gaagctcaac
    20161 atatttccca accaaagcaa tccttgtcgt tttcttgagg ttcatcactc tatcaaccat
    20221 agctgaccat tctgtcatat ctgcctgagg cacgtctagc ttcaagtgat cacagacgat
    20281 ttgatccatt gattgagcct gcaaattcag tggaatttga tacaaatgct ccacgtcacg
    20341 agattcaata acggcttctg ggttaacatc acaaaattgc gccagcttat tttttatccc
    20401 ctgctcaaca ggctcctcag tacgaatgac aagcatattc ggctgaatgc ctaagccgcg
    20461 taattcctta acagagtgct gtgtcggctt tgttttcatc tcgcctgctg cttttaaata
    20521 aggcagtagg gttgtgtgaa tatacatcac attttcagag ccgacatctg ccttcatttg
    20581 acgaagcgct tctaagaatg gcagactctc aatgtctccc acagttccac caacctcggt
    20641 aataatcacg tcagaatctg tggtcgtagc tgcgcgcttg atcttctcct ttaaggcatc
    20701 tgtaatgtgt ggaataacct gaacagtcgc tccaaggtat tcacccttac gctccttacg
    20761 aagcacctca ctgtagattt taccagttgt cacatttgag tatttattaa gattaatgtc
    20821 aataaaccgt tcgtagtgac caagatccaa gtcagtctct gcaccatcat cagtgacata
    20881 gacctcccca tgctgataag ggctcattgt cccaggatcg atattaatat aagggtcgaa
    20941 tttttgaatc gttaccttta ggccacgatt tttcaataaa cgtccaaggc tagccgctac
    21001 aatacctttt ccgattgatg agaccactcc gccagttaca aaaatgtact ttgtcataac
    21061 actcctttat ccttttgagt taagcctgac taactcgttt ttatttttaa aagatcgtcc
    21121 tactttagct agtaacgatt gggggctaag cttcccataa ggctaagcca tgagaccagt
    21181 aaccaaggct aagttattaa aacaaaaata gccccctatt aactagggag cttacctgac
    21241 ctcttaaaga ggtgcccgat taataatata aactataaga ggacatttgt caaatattac
    21301 tgttgctttt agaggctagc gatactcctg ctattcctcc tcttcctcat cttcttcgtc
    21361 ctcttcattg aggtcaacct cttcaaaatc gtcctctgga atgatttcat tgagctctga
    21421 atcgtaggac tctacttcag atttttcatc gtctggatct tcctcgtcat attcaatatc
    21481 agatgattca cgaacaaaat cctcatcctc tggatcatca gcgctatagt caatagcgtc
    21541 ctcatcaccg tccatgaagg cattgacacg tttcttcttg cgttttggtg cgccgtcttc
    21601 ttcatcttct agggtgatga tttcctcatc aatctcatca atagcatacc atgaacgtag
    21661 accccattta ttttcaccaa gtggaataaa gctaccatct gtattgagat cagtgtaaaa
    21721 aaatggtaaa gcatatcgaa tatcagcgtc agacttgcct aggtaatttt gaatctcatt
    21781 aaccaaatcg ctaaaataca tgtcattatc gcgaccacgc tcttctaaaa tagcacgagc
    21841 aacttcaatc atagaaagtt cgcttatttc ttgtcctgca aatacatcta atttcaaggc
    21901 agttctcctt attttatcat tctcccctat tttacgctaa aaataccgat tcgtcaaagc
    21961 ttttatcagg gaagaacagt attcttttta cccacttctc agccagcaag aacaaagcct
    22021 agcagcaacc agcttgattg ctcctaaacg cgataacaga agcatttcaa agagaagtgt
    22081 taactgtttg cctttaaacc atgaagcaac agcaaaacaa gaccaagtgc ttgcttagtc
    22141 ttgcttgtct atatcataac agcttatttt gcttttgctg agcttgtaat cacttctaca
    22201 gcttttttca taacaatgtc atgctttaac atatcagctg aaagcaatga gcgaacctgc
    22261 tcaactggca tgctatactc agctgcaagg tcgttaattt ctttttcaat ctcatcgtct
    22321 gaagcttcaa agccctctgc ctttgcgata gcctcaataa cgagattagt tttgacacgc
    22381 ttgtctgcct ctgcttcatg ctgcttgtga agatcttctt gacttgtgcc agttagctgg
    22441 aagtacatat caggtgaaat gccctgacgc tgcatgctag ccataaattc attaacggaa
    22501 cggtgaacct cgtcatgaac catttcctct ggtaattcca caatttcagc attctcaaca
    22561 gctaactcaa tagcagcacc ctctagagcg tcatcataag ctgcttcctt tgaagcctca
    22621 agctctttac gatacttagc ctttagctca tcaagtgttt caacttcctc gtcaatatcc
    22681 tttgcaagct catcgtcaag ctcaggtact tcttttgcct ttacctcatg aacagttgcc
    22741 acaaacttag cagccttacc tgcaagatct tcagcttgat aattttctgg gaaggttaca
    22801 ttaacctcaa cagtgtcacc agccttagcg ccaactagct gttcctcaaa gcctggaata
    22861 aattgtcctg agccaagctc aagtgagaaa ttgtctcctt tgccgccatc aaattcaact
    22921 ccatcaacag agcctacaaa atcaataaca actgtgtcac cttctactgc tgcttcttct
    22981 ttgacaacca gctcagcaag attgttgcgc tcgcgctcaa cctttgcgtc aacctcctca
    23041 tcagtaacct cttttgaagc ctcaacctca acagtaaggt ctttgtaatc accaagctta
    23101 acctctggtt ttgtgacaac ctctgcagta agtgtccatt cttgacactt ttccatagaa
    23161 accacatcaa tttttggctg tgcaacaaca tcaagctcaa gctctgcaac agcaccttca
    23221 taggctgctg gcagcacaat attcaaggcc tcctcataaa gaacctcttc accaaatctt
    23281 tgatcaaaaa caggacgagg catgtgaccc ttacggaagc ctggtgcatt taaatccttt
    23341 ttaattttat taaaagcttg atcaagagcg ggcttgattt tatcttgact aatggtaaat
    23401 gtaatcacgc cacgatttgt agctttgttc tcaaatgatg tagacattaa gtcatttctc
    23461 cttaaaataa tttagataca cctcattcta tcatattacc aagtgttttt aaagtttttt
    23521 atgcgtgaaa gtagggacag ggtttccaaa tatcagactc ttaactgaac cattaccaaa
    23581 aacctcatca gcttcaaaga aaaagagact ggaacaaaag tctgcctcca aaataaaaca
    23641 aacgaacaag acttgttttc tgagatccca aaaactagtc ttgttcgctt tttaattatt
    23701 tagactgggt aataaaatac attagctaag actttttaac atgcaactct ttttgtccca
    23761 gagtccaaac agtccttaat ctgtaagcca gatagttacg ctggaagtag gacagctact
    23821 gatttcttag ctagatgacc ggtaatgttg tgattggaaa catgataaac tgtgccagtc
    23881 actgcgtctt tgtagtcacc gtcagctagg gttgttgtag aagaaaagtc tttatcaacg
    23941 atggttaggt tggtgataac agcacccttt tgaccgcgtt caatcatgac tagaccttgg
    24001 tccataccag gattgcgaat atattctgat tgaccattca tcctattgcg gaattgatta
    24061 atcgcaacaa tggttggatc cttaaacaag tcactgccgg catcaccaat ttggctttct
    24121 ccagggaagc gtccattttg gccgccaccg ccacgaggac gtgaaaagaa gagcggtgct
    24181 ccctcattac gagcagcaat aattccccag ccaagcttaa tgtcctcatc tgttagcttg
    24241 gtagactctt catcatcgtt agcataggta tcatgagatt ctacccaagt gactaacttg
    24301 tcctctgaaa cgccatgcac ttggaaattc accaaatccc aatctttcac atagccttga
    24361 cctagcactt tacggattag cttaccatag tttgacgctg tcactcccat gatattgcca
    24421 tagcctgctt cgttgcaagc atcaccctgt aaaatttctc catattggaa tttagcacca
    24481 ttgttaagaa taaccttcca gaaatcgctg ttatgctcac ctggtaattc gatatgcttt
    24541 gcagcatcat acctaaagcc atctgctcca tcagctactg ctcgttttag ataattcagc
    24601 atgtattctt ggacagctcg attttgcgtg ttgaaatcat aaagtcctag caaggatttt
    24661 tgggttattt gataacgatc gttgaagttg acgattttgt catttccatg tgtccagtta
    24721 tctatggctg tgatcttagg gctaactgcc ttaatctcag aggttgtatg attcaaaaca
    24781 gcatcaacaa taatattgat cccatattta tcagcctcct gagccattgc cttaaattcc
    24841 tcttctgttc ctaattggta gttcccgata gtatagtctg ttggctgata atggtaatac
    24901 cagtttttca agtccttact accgccagct ccttcaatga cagcattaat aggtgaggtt
    24961 tgaatactag tgtagccagc ttccttaatg gcactcatgt tttctttgat ggtgttaaag
    25021 gaccagcacc aagcatgtaa aatagctccg tccttcatgg ctaccggttg attatcggac
    25081 tgcacctcct gagcactagc aaggttagct ggggctagag gagccaagcc tgaaagtacc
    25141 aagccaaggg tcaagctggt cactgataga gctttgagaa atctttttgt cttatgtgtt
    25201 accatatgta aactccgttc tttctgcgaa atcgctttcg ttggcgctta aaaaaataag
    25261 atgattctct gtactgtttg caaacaaaaa taggacctat gagagaagta taacatataa
    25321 atttcggtat gcataccatt tttagcaaaa aattagtgat ttttttaatt tttatttcct
    25381 ttgctaaagc ctctaaaacc aatcaaaata atgttgcata agtatttgcc ttttatttat
    25441 ctcataatca gactcattcg ctctaatctt ttgcacatgt taatgtcatt tatttgcaga
    25501 cctacgcaac caattgcaca gagctttgtt tccttcgtca gaaaaacctc aataaaacat
    25561 aaacaagaag ccattactct tcttgataat gtttggtgat ctattttcaa ccaggacttt
    25621 ttttggtaaa ctagctacga tagaaaggag ttgccatgac gtttatatta acatacttta
    25681 atcagctaca cctagaaaat atcatggtgc ttgtgttttc taaattagtg tcaatcacct
    25741 tattattgat tttctttgtg atcttcaaaa aaatcacgac agctttattt gaaaaggcaa
    25801 tcgccaagtc attttcctat tcaagacaaa ctgaagcaag gaaaaaaacc ttatccaagc
    25861 tccttcacaa caccctaaat tatgttttct attttcttct catctattgg attttgagcc
    25921 tacttggtat tccagtatct agtcttttag caggagcagg aattgctggt gttgctattg
    25981 ggcttggggc tcaaggcttc ttgtctgatg tggtcaatgg cttttttatt ctgtttgaaa
    26041 atcaatttga agtaggagac accgtcacca ttgcaggcat tgaaggaacc atctccagcg
    26101 ttggtattcg aaccactcag gtgcgaggct ttgatggcac actacatttt attcccaacc
    26161 gcaatattac agttgttagc aacaaatcac gcggcaatat gagagctttg atcgatattc
    26221 cactttattc ctcaaccgat ctagagcatg tgacccaaat catcaaggct gtcaataagc
    26281 gagaggtgcc aaatttccca caaattgtcg gacagcccaa cattctagga ccacaaacca
    26341 atcccaacgg acaattcacc tttcgcgtta gcatttttac tgaaaatggg cagcaattta
    26401 cgatttacta tagcttttat aagctctatc aagaggcctt actaagggag ggtatcaagc
    26461 taccaactgc atctgccata tcacccttag cctagcagta aaaaccattg ctttcttagc
    26521 atacaaaagc cctatcccgc agccaggtca tcagacttag actgctagat agggctattt
    26581 cttttggctc ttatttccga ataggatcag gctgatacct ggctcttaca ccaccaatta
    26641 atttgggccg acttgctaag gcagtcacat gagcaccacc aagctctcgc tgaataggca
    26701 caagcggcac ctgtacacgc ttaacatgca taccaattga ggtatctcca atgtcaaggc
    26761 ctgcatgagc agcaatggct tcaacctcaa ctggctgctt catgtatttg aaggctgcta
    26821 attgaccact tcctccagca tgcaagctag gcagcacatt gactatttct agccgatatt
    26881 cttcagcaac actttcttct aataccaagg cacgattaat gtgctcacac ccctgaaccg
    26941 ctaaatgaat ccctctgaac gacaattcct ccaatataag cttcacaata acctcgccca
    27001 cctctaagct agaatgctgg ccaatacgac caccaagtac ctcgctagag gacagcccta
    27061 agacaaacag ttgccctttt ttgatagcac tacgctccac aatatcaagc aagatagagc
    27121 gtgcttcttc tctcaatact tttaaattca ttgaatcacc tgcttaatca tctgacactt
    27181 tgaccagctg ttttttgacc cctaaataca gcagatagcc tacacctatg ccaagggtat
    27241 tttgagcagc attccccgaa atttctgaaa tagcagcgcc cataccatac attggaatag
    27301 ctgcaagaaa atacagacca accattatca cagaagcaag gcccacgcca agaaagcgat
    27361 gcctgccagg caagcctgct aagtagccct gagccccatg agcaacaaga ctaatcagca
    27421 tccaattggg gtaacctgag atcaaatcaa gcaaaaaagc tgataagccc ccaacaagca
    27481 taccctcctt tttcccaaga gaaaaggcag tcacatacac ccctgcatct aaaagactta
    27541 aaaaacctgt cggcgtggca atactcacaa acctgcccag gacaactgtc agggcagtca
    27601 agatagacac aagagctagc tctcttgtct gtttcatatt tatcataaga caactccata
    27661 atcatttgac tgttgaatgg cttcaaaaac aaggtcttta gcctgctcaa cagccctaag
    27721 cggtgaatat cccttagcta aataagcagc aattgcagct gcaaagctac agccagcccc
    27781 actgttttgt ttggccaaga ctggcttttc taaaaagcac agggtttttg cgtcataaaa
    27841 tagatctagg gcaactcgtt gatcaaaacg attcccaccc ttgatcacaa ccctcttagc
    27901 ccccatctca taaagctttt ttgccgcttc taccatttgc tccctgctat taatagcaag
    27961 ccctgccaag cgttctgctt ctcttaggtt gggagtaatc actgctgtta agggaaaaag
    28021 agagcgcaaa gcctgtgtca tttccacaac tgtctgatct tgattttcct taaatactaa
    28081 aacaggatct aaaacaacag ggatatcctt ttttagctct aaaaacaggg ccacctgctc
    28141 tgctatttca ggtcttggca aaagaccaac tttgattgcc tgaaaaggaa tagctgctaa
    28201 gctagacaac tgctttgcca gcaaatcagt cgcaacaggg tgaatgctga aacctttagc
    28261 atcacagctt gttaagcagg tgatagctaa aaatgcaaag ctatcgagct gatgaagcac
    28321 tgccaaatca gcctgcaaac caccaccgct gaatatatca ctcccagcaa tcgttaatac
    28381 cttattcttc ataaatgatt tccttcaaat aaagaccatt accagccgct gtcggtccag
    28441 ctagctgccg attcttactc tctaaaacga gcctgatttg ttcaatgggc aaccgaccat
    28501 tgccgatctt aagcaaggtc ccaaccatat ttctaacctg cttataaaga aagccattcc
    28561 ctgaaaacgt aaaaacaaga aaaccagttt tagggtcctg agtgagggta gctgctgtaa
    28621 tggtacgaac cttattttta acagaggttc ccgcagctgt aaagcctgta aaatcatgcg
    28681 tcccaaccaa atccttaatc gcagcctgca ttttcgcaat atctaaggga taagggtaat
    28741 gggtcgcata atggcgcatc ataggatttt taggacgacc aatatccact aagaattcat
    28801 aggttttgaa atgcttatgg tagcgagcgt gaaaatcatc tgctgcaatc tccagactga
    28861 tcacatcaat atcatctggt gtctgggtat caagtgcaaa gcgaagcttt tcagggtctc
    28921 ttttttgctc caaatcaaag tgaatcactt gaccataagc atgcacacct gcatctgttc
    28981 taccagctcc atgaatctgt atcccttgac cacctgtcaa tttttgcagg gtcttttcaa
    29041 tctcttcttg taccgtacgt gcctgacttt gtctctgaaa accagaaaat aaggtcccat
    29101 cgtaggaaat aattgcttta tatcttgtca tgctattatt ctaccatttc ttccagccat
    29161 cagaaaagag catttacggc ttttgtcccc atacagtttt cgattagctt tgataatcaa
    29221 gcttgatttg acgccaacag gcaaaaaaag gctactgaca aggactagct tttctgctat
    29281 aatttctcta atattcaata agtagactgg agagcaaatg aaggtaacaa aatttggcgg
    29341 cagctcctta gcatctgccc agcagttaga aaaggtcttg gctattatca aggacgatcc
    29401 tgagcgtaaa atcatcgttg tctccgcacc aggcaaacga tcccctacag acacaaaggt
    29461 gactgatgca ctcattgctt attacaaagc ctacgtctca gaccgtcatt atcacaagca
    29521 tttggaatgg attatcaatc gttaccaaca aatctgtaat gacctaactc tagatagcaa
    29581 aatcatcacc caaattaaag cttccttaga gcaattggca cggcttccaa aagaacataa
    29641 tccctattta tacgatacct ttcttgcggc cggtgaggac aataatgcta agctagtagc
    29701 tgcctacctc aaggcaaatg gcttaactgc aagctatctc caccccaaag atgcaggtct
    29761 aatcgtaagc agtgagccac agcatgcacg tcttcttcca atcagttacg ataagctaga
    29821 ggccttaaag gatcatgatg acattcttgt tattcctgga ttctttggtg tgacaaatga
    29881 aaaccagatt tgtaccttct cacgtggtgg ctctgatatt accggctcca ttattgcagc
    29941 aggagtcaca gctgacagct atgaaaattt tacagatgtc aatggcatct ttgctgccca
    30001 ccctggtgtt gttaagcagc cacagacgat cactgaatta acctacagag aaatgcgcga
    30061 gttagcctat gctggctttt ctgtcctcca tgatgaagca ttaatccctg cttaccgagg
    30121 gaaaatccca atcgtcatca aaaacactaa caatcccagc cacccaggta caacaattgt
    30181 tcttgagcac cagaggaaat ccaatcccgt tgtcggtata tcaggtgatg atcactttgt
    30241 cagcattaac ctatctaaat acctcatgaa cagagaaatt ggatttgggc gcaagctcct
    30301 tcagatatta gaggacctca atatcagatg ggagcacatg cctacaggta ttgatgacct
    30361 atcaattgta cttagagaaa gagaattgac ccccatcaaa gaagaagaaa tccttcgcag
    30421 acttgtccag caattagagg ttgatgaggt gtccatcacc aggaaccttt ctattatcat
    30481 gatagtcggt gaaaacatga aaagtcatat tggtgtcaca tctgccgcaa caaaggctct
    30541 atctgaacat catatcaata ttgctatgat ttcccaaggc tcaagtgagg tatctgtcat
    30601 gtttgtcatc aatagcaccg atgaaaaaaa ggccattaga gccttatatc aaaccttttt
    30661 tagccctgat cgacccctgt aaagctccat ataacatctc ttgttaacac caagcttcaa
    30721 aaacagctca caagctagac agtactccta gcctatgagc tgttttgatg atctaaaact
    30781 atcaagatta agcatcggta gtaacgactt aatatgctca cagctatcat aaactctagc
    30841 tttaccttat tgaggaaaag aaaaccagtt ttcacctcag ctaagattaa caacaagcga
    30901 ttaagcactt gctaaaaaca gatagacttc aaaagtgaga catatgtata atttctacca
    30961 gatctaaata aatatagcag cagagcaccg agtttaataa gccatttctg acatgataaa
    31021 ctcgccaagc tctccacaga tcaagatttg ccttatcaat tgatacaaca gccagcattc
    31081 tcaaagatgc acaagatcca tcacagtcta gccatctccc tgcacagtaa g
//
LOCUS       DARYNN010000024        30531 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.024, whole genome shotgun sequence.
ACCESSION   DARYNN010000024 DARYNN010000000
VERSION     DARYNN010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30531)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30531)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30531
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.024"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     regulatory      696..821
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            894..1472
                     /locus_tag="TVB59_001026"
     CDS             894..1472
                     /locus_tag="TVB59_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007894892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEL1009927.1"
                     /translation="MSKTHQLVMVAILSAISFCLMFVGFSIIPGASFLKIDFSIIPIL
                     LGLVLMDLKQANLILAVRTLLRLALNNHGVNDLIGIPMNVIAVALFITAFALIWHRQK
                     GLVTYVLASLVGTGLLTLGMVVMNYVFAIPLYAKFAGFDIKAFIGTARYIFTMVIPFN
                     LLEGLIFAIVFYFVYIAGKPILERYPNSYHET"
     gene            1462..2112
                     /locus_tag="TVB59_001027"
     CDS             1462..2112
                     /locus_tag="TVB59_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEL1009928.1"
                     /translation="MKHKQQHLLLSSFAMLLFVVLGYIVKFFPEDLTSFDSQLRLALR
                     GHLPEGLTQFFKGITVAGNVSTQAVIVVVAVLALLALSWRAEALFVLSNGVFAALLIW
                     VLKLLYQRPRPSIEHLVHASGYSFPSGHSMGSLLIIGSLLIICHQRLQSASLRWLVDI
                     ALLALILLIGLSRIYLGVHYPSDVLAGYALGFGILQLLYPFYDQKRFEWRFQLKQK"
     gene            2303..3226
                     /locus_tag="TVB59_001028"
     CDS             2303..3226
                     /locus_tag="TVB59_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623410.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HEL1009929.1"
                     /translation="MTKRYQTLNEYYRRLFGAKIFKVPIDAGFDCPNRDGTVAHGGCT
                     FCTVSGSGDAIVAPDAPIREQFYKEIDFMHRKWPEVNQYLVYFQNFTNTHDKLEVIRE
                     RYEQAINEPGVVGINIGTRPDCLPDETIAYLAELSERMHVTVELGLQTTYEATSQLIN
                     RAHSYDLYKETVQRLRQYPNINIVSHLINGLPGETHEMMIENVRRCVTDNDIQGIKLH
                     LLHLMTNTRMQRDYHEGRLQLLSQKDYVSIICDQLEIIPEHIIIHRITGDAPRDMLIG
                     PMWSLNKWEVLNAIDLEMERRNSWQGCKLKG"
     gene            3239..4024
                     /locus_tag="TVB59_001029"
     CDS             3239..4024
                     /locus_tag="TVB59_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 3'-phosphotransferase"
                     /protein_id="HEL1009930.1"
                     /translation="MKQRLIAGEELSLPPVLKKLLQNSLVYDSSSSAEARVYAIDKGQ
                     GYFLKTAAKGRLAKEAALTRYCHSKGLATEVLDYISGDQDWLLTAKVAGEDASHIEYL
                     SDPKRLCRILVDHMLKLHSLSLSDFPVADKTLAYIEAAEAGYHQGRFNQCFLPPQQRF
                     QSQEEAYRRIQELKLLLQHETLIHGDFCLPNMILDRWQFQSMIDWGEAGKSDRHIDLF
                     WLIWSLQFNLKTDRYKDYVLDCYGRRHIDLDILDGIAAFEVFA"
     gene            4034..4591
                     /locus_tag="TVB59_001030"
     CDS             4034..4591
                     /locus_tag="TVB59_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL1009931.1"
                     /translation="MIKRPIHVSHEFLKEVLDKQSIAVDATMGNGYDTAFLASLSQRV
                     YAFDVQQQALTKTQERLEQQGLTNAELILAGHEQVDQYVKEPIRAAIFNLGYLPNADK
                     SLITRPETTILALAKILDRLELGGRIAIMVYYGHDGGSREKEELLDYIGQLNQRQVTA
                     MLYQPINQMNQPPFLIMLEKIAATD"
     gene            4719..6053
                     /locus_tag="TVB59_001031"
     CDS             4719..6053
                     /locus_tag="TVB59_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEL1009932.1"
                     /translation="MEDPVSQPLLIQFLLLVILTLLNAFFSASEMALVSLNRSRVEQK
                     AADGDKRYDRLLRVLEQPNNFLSTIQVGITFISLLSGASLSASLGQVISGWLGGSATA
                     QTAGSIISLVFLTYVSIVLGELYPKRIAMNLKDKLAVISAPVIIILGKLVSPFVWLLS
                     ASTNLLSRITPMTFDDADERMTRDEIEYMLTNSEATLDAEEIEMLQGIFSLDEMMARE
                     VMVPRTDAFMIDINDDTLDNIKEILKQSFSRIPVYDVDKDKVIGLIHTKRLLESGFRQ
                     GFENISMRKLLQEPLFVPETIFVDDLLRQLRNTQNQMAILLDEYGGVAGLVTLEDLLE
                     EIVGEIDDETDKAEQFVHHIDDNTYIVTGTMTLNDFNEYFDTELESDDVDTIAGFYLT
                     GIGTIPSQKEKESFACDSKQKHLVLVNDKVKDGRITKLKLTISNIEQNITED"
     gene            6130..6921
                     /gene="pflA"
                     /locus_tag="TVB59_001032"
     CDS             6130..6921
                     /gene="pflA"
                     /locus_tag="TVB59_001032"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEL1009933.1"
                     /translation="MVEVDYGQVTGMVHSTESFGSVDGPGIRFIIFLQGCKMRCQYCH
                     NPDTWAMETNQSQRRTVNDVLKEALQYRHFWGKKGGITVSGGEAMLQMDFITALFTEA
                     KKLGIHTTLDTCGFAYRPTPEYHELLETLLAVTDLILLDLKEIDEEQHKLVTRQPNKN
                     ILQFARYLSDRQVPVWIRHVLVPGLTDIDDHLVRLDAFVKTLRNVDKFEVLPYHTMGE
                     FKWRELGIPYQLEGVKPPTKERVENAKKLLHTESYTEYMNRIHQS"
     gene            7421..8356
                     /locus_tag="TVB59_001033"
     CDS             7421..8356
                     /locus_tag="TVB59_001033"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEL1009934.1"
                     /translation="MSKLLVFGHQNPDTDAIASSYAFDYLAKKAFDLDTEVVALGDPN
                     EETAFALDYFGVSAPRVVTSAKAEGASHVILTDHNEFPQSISDIREVEVYGIVDHHRV
                     ANFETANPLYMRVEPVGSASSIVYRLFKENRVDVPKDIAGMLLSGLISDTLLLKSPTT
                     HASDHRVAAELAELAGVKLEEYGMAMLKAGTNLASKSEAELIDIDAKTFELNGNAVRV
                     AQVNTVDIAEVLERKEAIEAAIREVMASEGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFSFKLEDNHAFLAGAVSRKKQVVPQLTESFGA"
     gene            8423..9076
                     /locus_tag="TVB59_001034"
     CDS             8423..9076
                     /locus_tag="TVB59_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEL1009935.1"
                     /translation="MITIFNPDKLTRQPFFQDLIHYLNQHDDVTLRHIKQAFSHVKGI
                     DKALEAYIQAGYICRKNRRYYLCLPLLDDLQQVTLEDLIFVDRASDLYEALMALVFET
                     VLSNQTNQVLIKEKTTIDRDKLTLANYFYRLRRGEALSDEQLRLYALLGDVNQDYALK
                     YMTSFLLKFARKEIVMQKRTDIFVNALELLGYIEKVEATKYCLKLAFDKEQLIFYAD"
     gene            complement(9181..10179)
                     /locus_tag="TVB59_001035"
     CDS             complement(9181..10179)
                     /locus_tag="TVB59_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEL1009936.1"
                     /translation="MTATKRHVPLFLGLISGLVCLMIISLSIGESSMSPLEVVRVLFG
                     KSTADMALIITNIRLPRILAACIGGGSLALSGLMLQSLTRNHLADSGILGINAGAGMA
                     ITLVISYSTSNSLTSRQGLPLMTISGAMATIVLVYLLSLRHGHIDPIRLIVTGVGLST
                     MLSSLMIAFVGNVNRYKVDYVIHWLSGQLTGDDWSKLSIVAPLLGITWLLAFSQAYKL
                     NIMALNDEASMALGFKLHQYRTIVLALSAILSALSVILVGNITFIGLIAGHTSKRLVG
                     ADHRLSLPVSLFIGMILLLLADTIGRVYLVGSNIPTGILVSIIGASYFLYLMVKMT"
     gene            complement(10176..11201)
                     /locus_tag="TVB59_001036"
     CDS             complement(10176..11201)
                     /locus_tag="TVB59_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEL1009937.1"
                     /translation="MTAQHHTKPKLAKAAPPWLILTFISLTLVLAIYCSLRFGAVSLS
                     HQELYHILLGKQDQGQKASIILDIRLPRLILAALVGAALAVSGAIMQGITRNPIAEPG
                     LLGINSGAGLALVIGYAFSPHLHYSTIILLSLLGSLLATLLILSLAYQAGKGYTQMRL
                     ILAGAMISMLLSAIGQGITTYCHLANAIIGWQAGGLIGVNWQMVSYVAPLIICGLALS
                     YLLAYHLTILSLSQEQAKALGQRTFLISLIFIGLVLLLSSAAVAVAGSISFVGLIIPH
                     AITLVTAKDYRWILPLATLLGASFMLWVDFACRNINPPYETPLSALISFIGLPCFLWL
                     VRKGGRF"
     gene            complement(11211..12149)
                     /locus_tag="TVB59_001037"
     CDS             complement(11211..12149)
                     /locus_tag="TVB59_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-hydroxamate ABC transporter
                     substrate-binding protein"
                     /protein_id="HEL1009938.1"
                     /translation="MKKLLLILTVFVTAFTLVACSSQSKQQESTSKASLSHKPKIAGV
                     TYYGDIPVKPKRVVSLAATYTGYLAKLDLHLVGVTSYDKKNPVLTKSITQAKQVAATD
                     LEAITALEPDLIVVGSTEENIDQLAKIAPLISIEYRKRDYLQVFSDFGRIFNKEKETD
                     QWLADWKQKTSDYEKEIKQVTGSAATFTIMGLYEKEIYLFGKDWGRGGEIIHQALHYD
                     APEKVKKEVFKQGYLSLSQEVLPDYIGDYVIVAAEDDQTGSALYESDLWQQIPAVTNN
                     HVIKVNANVFYFTDPLSLEHQLEVLKKAILSTGASQ"
     gene            complement(12174..12953)
                     /locus_tag="TVB59_001038"
     CDS             complement(12174..12953)
                     /locus_tag="TVB59_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1009939.1"
                     /translation="MSTISAERISAGYDQSLIISNLSVTIPEGKVTTIIGANGCGKST
                     LLKTLARLLPLKAGQVLLDGQAIARLATKDVARTLAVLPQLQEATTATVYELVSYGRY
                     PHQSYLGQLSQADKDKICWAMEVTSMAPYAHQAVDALSGGQRQRAWIAMALAQDTDII
                     FLDEPTTYLDMNHQLDILELLKELNQVSGKTIVMVLHDLNLSARYSDHLIAMKNGHIK
                     YSGEVNQVMTPEMIQDIFQVKAQLVTDPLYHCPTLLTYQLI"
     gene            complement(13213..14658)
                     /locus_tag="TVB59_001039"
     CDS             complement(13213..14658)
                     /locus_tag="TVB59_001039"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEL1009940.1"
                     /translation="MITIEHLLTILKKDHNFREVLDQDGYHFNYSGLQFDSLSYDSRQ
                     ADEQTLFFAKGSAFKADFLRQAIAKGLRLYVSEIDYQVGIPVILVNNIKHAMSLAAMA
                     FYDYPQNKLKLLAFTGTKGKTTAAYFAYHMLKESHKPALLSTMNTTLDGQHFFKSQLT
                     TPESLDLFAMMAQCVANGMTHLVMEVSSQAYLVGRIYGLTFDVGVFLNISPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVVVNSGMEHFNILAEQVADKPHDFYGKGACNRLLQRQA
                     FSFQAAGKVAGDYAIQLIGSFNQENAMAAGLACLRLGASLEDIRQGIAKTNVPGRMEV
                     LTMTNQAKVFVDYAHNGDSLEKLLSVVEEYQKGQIYLILGAPGNKGESRRADFGQVIN
                     QHPNVRIILTADDPNFEDPQLISEEIASYIHREVDIIIDRKEAIKTGMERCQNEQDAL
                     IIAGKGADAYQIVKGQKTAYAGDLAIAKSYL"
     gene            14744..16375
                     /locus_tag="TVB59_001040"
     CDS             14744..16375
                     /locus_tag="TVB59_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEL1009941.1"
                     /translation="MSTEKKQLTQEQLMVQGAAWSTAGNFISRLLGVLYIIPWYIWMG
                     QYAIQANALFNMGYNVYAYFLLISTTGLNVAIAKQVAKYNSMGQQEHSYQLIRSTLKV
                     MLVLGLIFSVLMYLGSPLFARLSGGDETLVPIMHSLSLAVFVFPVMSVIRGIFQGYKE
                     IKPYALSQIAEQLVRVIWMLLTTFFIMKMGSKDYIAAVTQSTFAAFIGMIASMAVLFY
                     YFWTQGLLKAIFTKTEHAIPIDIKGLLIETLKESIPFIITGSAIQAFQLLDQWTFVNT
                     MTLFTSYTRSQLWVLFGYFNANPAKITMVLIAVAASIGSVGIALLTENYIKKDMRAAG
                     RLIINNIEMLLMFLLPALTGAIILARPLYTVFYGSSEGQAVRLFVAVLCLTLLMALYT
                     LFSPMLQALFENRKAIYYFAYGVFVKLVLQVPLIYLFHAYGPLLATTLGLLVPIYLMY
                     RRLHQVTRFNRKLLHKRILLTVIETALMGLIVLLANWFLGYLFKPTGRLTSLLYLVII
                     GGLGMGVYAYMTLLTRQLDKLIGSRAARYRQKLGL"
     gene            16525..17154
                     /gene="upp"
                     /locus_tag="TVB59_001041"
     CDS             16525..17154
                     /gene="upp"
                     /locus_tag="TVB59_001041"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEL1009942.1"
                     /translation="MGKCQVISHPLIQHKLSILRRQDTSTKDFRELVNEIAMLMGYEV
                     SRDLPLEDVEIQTPVAKTVQKQLAGKKLAIVPILRAGIGMVDGFLSLVPAAKVGHIGM
                     YRNEETLEPVEYLVKLPEDIDQRQIFIVDPMLATGGSAILAVDSLKKRGAANIKFVCL
                     VAAPEGVKKLQEAHPDVDIYTAALDERLNDHGYIVPGLGDAGDRLFGTK"
     gene            17385..17975
                     /locus_tag="TVB59_001042"
     CDS             17385..17975
                     /locus_tag="TVB59_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="HEL1009943.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRHRLEKILAQNAGK
                     TIKQIHKDAERDYWMSAEETLAYGFIDEIMENNELA"
     gene            18080..18526
                     /locus_tag="TVB59_001043"
     CDS             18080..18526
                     /locus_tag="TVB59_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HEL1009944.1"
                     /translation="MLIINEELFAIEKAIEQLVQDIRTSSQYQAYALAKKAFEADLAL
                     QTELALFEELKQDYELRQDLLKLCPDARALRCQLLHQKRQLDLHPLVADLRLAQVDLQ
                     EVLATISTAIAEAVSEDILVDTGLPLATNRPRHELGPYQNIKEKST"
     gene            18527..18811
                     /locus_tag="TVB59_001044"
     CDS             18527..18811
                     /locus_tag="TVB59_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEL1009945.1"
                     /translation="MFQKQQRIGLVIYLYYNRDARKVMKYGDLYYHSRRSRYLVIYIN
                     KEDMEEKLKDISRLTFVKEVKVSAFDDIDCDFVGNLHREPLEPQALPEQG"
     gene            19127..19762
                     /locus_tag="TVB59_001045"
     CDS             19127..19762
                     /locus_tag="TVB59_001045"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEL1009946.1"
                     /translation="MTRGKLITFEGPDGAGKTTVLERLVPLLQAALGQTIVTTREPGG
                     VAIAEKIRQLILDVSHTTMDDKTELLLYIAARRQHLVEKIMPALESGHLVLVDRFIDS
                     SVAYQGAGRGLDKQAIQWLNHFATDGVDPDLTLYFDVPSELGLARIAQNTEREINRLD
                     LEQLDLHQRVRKGYLELALENPQRIVKIDASQDLESVVSAALAAIITHSQA"
     gene            19776..20651
                     /locus_tag="TVB59_001046"
     CDS             19776..20651
                     /locus_tag="TVB59_001046"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEL1009947.1"
                     /translation="MDLAQKAPRVYQAFQEILQKKRLNHAYLFSGDFANFDMALFLAK
                     TLFCEQKRGNAPCHHCRACQLIEHNDFSDVTILEPVGQLIKTDTVKEMMTNFSQTGYE
                     GRRQVFIIKDCDKMHVNAANSILKYIEEPQGDCYMFLLTNDDNQVLPTIKSRTQVFHF
                     PKDEHYLSELAQKKGLLKHQADLLARLAANAQQLTAFSENTRLLELMAQAERFVSIWF
                     QDKEQAYLELNRLVQLAEEKEEQDMALTLLTLILAKDYSRQNAFTYLEAVYQARLMWQ
                     SNVSFQNTLEYMVIS"
     gene            20648..21448
                     /locus_tag="TVB59_001047"
     CDS             20648..21448
                     /locus_tag="TVB59_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEL1009948.1"
                     /translation="MISTIGIKYCDTCSVRYVQTDQAFPVQTKLVISDGKGSRLAVVN
                     SPIKSFCKDDLPKDMPSVLRPANDMDYKAYQQNLQLAAQSKQKVAEMIDRNGLDMTLV
                     DIVFSLERRYVLITFTAQERVDFRQLLKDLAAYFKTRIELRQINSREEARVYGGLGPC
                     GRPLCCSSFLGEFPPVSIKMLKHQGLSLHSAKSLGCCGRLLCCLQYEDDFYQESKKKF
                     PDYGTIVRTAQGPGEVAGIDLFTDTIQVRFKDQLALVTYALEEVKVSE"
     gene            21441..21764
                     /gene="yabA"
                     /locus_tag="TVB59_001048"
     CDS             21441..21764
                     /gene="yabA"
                     /locus_tag="TVB59_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEL1009949.1"
                     /translation="MNKKELFDAFDGFSQNLMVTLAEIEAMKKQVQGLVEENTILRLE
                     NTKLRERLSQLEHENLAKTSSKQGKDHLEGIYDEGFHICNFFYGQRRENDEECMFCRE
                     LLDRK"
     gene            21769..22635
                     /gene="rsmI"
                     /locus_tag="TVB59_001049"
     CDS             21769..22635
                     /gene="rsmI"
                     /locus_tag="TVB59_001049"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEL1009950.1"
                     /translation="MQIQKSFKEEKESGVLYLVPTPIGNLEDMTFRAVNVLKEVDIIC
                     AEDTRNTGLLLKHFGIKTKQVSFHEHNAYDKIPDLLDLLLAGRSLAQVSDAGMPSISD
                     PGHELVRAAIDRDITVVALPGASAGITGLIASGLAPQPHLFYGFLPRKAGQQRAFLMT
                     KADYPETQIFYESPYRVKDTLTNLLACYGDRQVVLVRELTKLFEEYQRGQISEVLTYL
                     ADHPLKGECLLIVAGANQADASEPAEDLDLLALVQQAIAAGMKPNQAIKTIAKDYKVN
                     RQELYQQFHGLG"
     gene            23141..23296
                     /locus_tag="TVB59_001050"
     CDS             23141..23296
                     /locus_tag="TVB59_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEL1009951.1"
                     /translation="MATEMLASFEGGKNNWAANVSGVIGAGSAGAALGFPVCGVACGS
                     IGVTGGF"
     gene            23355..23555
                     /locus_tag="TVB59_001051"
     CDS             23355..23555
                     /locus_tag="TVB59_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEL1009952.1"
                     /translation="MEHYRALAISEMQDISGGNAAGNAVIGGLGGLKTGITFCKIPHP
                     VLKGVCIDGFTALGACLAYKVN"
     gene            24223..24816
                     /locus_tag="TVB59_001052"
     CDS             24223..24816
                     /locus_tag="TVB59_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HEL1009953.1"
                     /translation="MIIKKLSVIALTSLSLISLSACRQQNQALGQNGSAQNHRKASVS
                     EDKAKELAFKDASITAADAQRLKLTKETDDGRVVYDIEFDAKDQEYSYTIDANTGEIL
                     EKSSEPITEAPASAQAAGGQADQAAGISEDKAKELAFKDASITAADAQRLKLTKETDD
                     GRVVYDIEFDAKDQEYSYTIDANSGDILEKSSEPVYD"
     gene            25156..26661
                     /gene="glpK"
                     /locus_tag="TVB59_001053"
     CDS             25156..26661
                     /gene="glpK"
                     /locus_tag="TVB59_001053"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEL1009954.1"
                     /translation="MGTETYIMAIDQGTTSSRAIIFNKKGEALVSSQKEFPQLFPQAG
                     WVEHNANHIWNLVQSVIADAFIESGIKPEQIEAIGITNQRETTVVWDKQTGLPIYNAI
                     VWQSRQTASIAEQLKRDGYTKMIHEKTGLVIDAYFSATKLRWLLDHVPGAQERAERGE
                     LLFGTIDTWLVWKLTDGAVHVTDYSNAARTMLYNIKELKWDDEILALLNIPKAMLPEV
                     RSNSEIYGKTASFHFYGGEVAIAGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GQEAQLSSSNLLTTIGYGINGKVYYALEGSIFIAGSAVQWLRDGLRMIKTSFESEQLA
                     LASTNADEVYVVPAFTGLGAPYWDSNARGSVFGLTRGTTKEDFVKATLQSIAYQVRDV
                     IDTMQVDSGITIQQLRVDGGAAMNNMLMQFQADILGIDIARAENLETTALGAAFLAGL
                     AVGYWKDMETLKQLNATGQLFKASMSESRREKLYQGWKRAVKATQFFAEEL"
     gene            26835..27479
                     /gene="fsa"
                     /locus_tag="TVB59_001054"
     CDS             26835..27479
                     /gene="fsa"
                     /locus_tag="TVB59_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEL1009955.1"
                     /translation="MKFFLDTANVEAIRAINELGVVDGVTTNPSIISREGRDFETVIK
                     EICEIVDGPISAEVTGLTAEEMIAEARNIAKWHDNVVVKIPMTTEGLKATNVLSQEGI
                     KTNVTLIFTVSQGLMAMKAGATYISPFIGRLEDIGADPYQLISDLRGIIDLYGFQAEI
                     IAASIRTAAHVEAVAQLGAHIATIPDPLFAKMTEHPLTTNGLKTFMEDWASFKK"
     gene            27863..29851
                     /gene="tkt"
                     /locus_tag="TVB59_001055"
     CDS             27863..29851
                     /gene="tkt"
                     /locus_tag="TVB59_001055"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEL1009956.1"
                     /translation="MTFDAIDQLAVNTVRTLSMDAIQAANSGHPGLPMGAAPMAYVLW
                     NHVMTVNPKTSRRWSNRDRFILSAGHGSAMLYSLLHLAGYDVSIEDLKNFRQWGSKTP
                     GHPEVNHTDGVEATTGPLGQGVANAVGMAMAEAHLAAKFNRPGFDIVDHYTYALNGDG
                     DLMEGVSQEAASLAGHLKLGKLVLLYDSNDISLDGPTSMAFTEDVKGRFEAYGWQHIL
                     VKDGNDLEAIAKAIEEAKAETEKPTIIEVKTIIGFGAEKQGTSAVHGAPLGAEGIAFA
                     KKSYQWTHADFEVPQEVTERFRQGLQARGEQAEQAWNDLFAAYEAAYPELAAEYKKAF
                     ANEAAEVELQAHELGTAVASRVSSQQAIQQISEQVPAFWGGSADLSASNNTMVKAETD
                     FQPGHYAGRNIWFGVREFAMAAAMNGIALHGGTRVYGGTFFVFSNYLLPAVRMAALQQ
                     LPTVYVMTHDSIAVGEDGPTHEPIEQLASVRSMPNLNVIRPADGNETNAAWKRAIAET
                     DRPTMLVLTRQNLPVLEGTKELAEDGLNKGAYILSEAKGDLDGIIIATGSEVKLAMDT
                     QAALAADGIHVRVVSMPSQNIFDEQPASYKEEILPAAVTKRLAIEAGSSFGWAKYVGL
                     AGKTLTIDTWGASAPGNRIFEEYGFTVEHATELYKSLS"
     gene            complement(30033..>30531)
                     /locus_tag="TVB59_001056"
     CDS             complement(30033..>30531)
                     /locus_tag="TVB59_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1009957.1"
                     /translation="RGEKGEQGPRGEKGEQGQRGEKGDQGQRGEKGDQGQRGEKGDQG
                     QRGEKGDQGQRGEKGEQGQRGENGEQQPKGDQGKDTKPSVPKAPESPKMPEKPQAPEK
                     APAPKAPKASEQSASPKAPAPQSTPSKKAVLPATGEASHPFFSLAALSVIASAGLLTL
                     KRKKS"
BASE COUNT         8367 a         5990 c         7358 g         8816 t
ORIGIN      
        1 gcgatcaaga cacagaacag gggctatagc agcctgatgt gagacaagaa ggacttactg
       61 tcctaccagc tacagtcact acactgctag agcttgcggt gtgagcagca gtaagaagca
      121 aaggcgctgc cctagagggc tgatgaatca ccatcaccag tttggagcca ttagctgtgc
      181 caaaggtttt ctaaagccaa aaagaaaaaa ctccgattgg agttcagaat gtaggcaaac
      241 cctatcagcg atagaaaaat tgaacattta gaaattgact atcatatcat gaaaactctg
      301 ggaaatgctg atattacagt atttttcaga cttcttttgt ttttttgatt aaaagaaaaa
      361 gattgaagaa aaccgtctaa aatggacttt ttcttcaatc tgaaaactct gattggagtt
      421 ttcattggtt aggtgtgtct atgaccgtaa aggggacaac ggtagtaata ccagagcagg
      481 ttattggagg tttcttctag tctgctcttt tttgccttga gctaggctag tgccatgtca
      541 cagggtggcc tacctcgtag agagctttgt agcctcaaag tgatttttct tgctgttgct
      601 ttcatctagc ttttttgcct gatgtcttgt gtttgttgga aaagctaggc ttcaaaaaaa
      661 tgtcttgcgc tataggttta aatttgctat gctataagtg tcttcagggc agggtgtaat
      721 tcccgaccgg cggtgactag tgcagctaga agtccgcgag cgcaagctga tgtggtgtga
      781 ttccacaacc gacagtaaag tctggaagag agaagaccgg gtttttgagt tgactttttg
      841 cctgctcata cgaaggagct tctttcaatt tgtcaaaatt ggaggaattt tttatgtcaa
      901 aaacacatca actggtgatg gttgccattc tttcagccat atccttttgc ctgatgtttg
      961 tggggttttc cattattcca ggagccagct ttttaaagat tgattttagt atcattccga
     1021 ttttgttagg cttggtcttg atggatctaa agcaagctaa cttgatttta gcggtgagga
     1081 ccttgcttag actagcctta aacaatcatg gcgttaatga tttgattggt ataccgatga
     1141 atgttatagc agttgcgctt tttatcactg cctttgcctt gatttggcat cgtcagaaag
     1201 ggctggtcac ctatgtacta gctagtcttg tggggacagg gctgttaacg cttggtatgg
     1261 ttgtcatgaa ctatgtcttt gctattccct tatatgccaa gtttgctggc tttgatatta
     1321 aagcttttat tggtactgct cgctacatat ttacaatggt cattcctttc aaccttttgg
     1381 aggggctaat atttgcaatt gtcttttatt tcgtgtatat tgcaggtaaa ccaattttag
     1441 agagatatcc gaattcatat catgaaacat aaacaacaac atctgctatt gtcttccttt
     1501 gctatgctac tatttgtggt gcttggctat attgttaaat tttttcccga agacctaacg
     1561 tcttttgata gtcagcttcg gttagcccta agaggtcatc tgcctgaagg gctaacccag
     1621 ttttttaaag ggatcactgt agctggaaat gttagtacac aggcagtgat tgttgttgtt
     1681 gctgtgctgg ctttattggc cttgagctgg agagctgagg ccttatttgt cctatcaaat
     1741 ggtgtttttg cggccctttt gatttgggtg ctaaagctct tgtatcaaag accaagaccc
     1801 agcattgagc atttggtgca tgcttctggc tattcttttc cgagtggcca ttcgatggga
     1861 agccttttga ttattggaag tctgctgatt atttgccatc aaagattgca gtcagcctcc
     1921 ttacgctggc tggttgatat agcccttttg gccttgattt tgctgatagg cttgtcacgc
     1981 atttatctgg gagtgcatta tcctagcgat gtgttggctg gctatgcctt aggctttggc
     2041 atacttcagc tgctttatcc tttttatgat caaaagcgct ttgaatggcg ttttcagcta
     2101 aagcaaaagt aaatccagtg atcagtcagc tgtatggcgc gttacagatc agttctagaa
     2161 aagctagtga ttgaaggcag gtctcttcca gaggtcttct tcaatccttt ttagttgcct
     2221 tgctttggct catcaatcag agaagtagca gccaattgag atcttctgct gttaatcggg
     2281 ggatttgtgc tacaatagag gcatgacaaa aagatatcag accttaaatg agtattatcg
     2341 tcgtttattt ggtgctaaaa ttttcaaggt gcccattgat gctggctttg actgtcctaa
     2401 tcgtgatggg acagttgctc atggtggctg caccttttgt accgtttctg gctcaggtga
     2461 tgcgattgtg gcgcctgatg cacctatcag ggaacaattt tacaaagaaa ttgattttat
     2521 gcatcgcaag tggcctgagg tcaatcagta tttggtttat tttcaaaatt ttaccaatac
     2581 gcatgataag ctagaggtta ttcgcgagcg ctatgagcaa gcaatcaatg agcctggcgt
     2641 tgttggtatc aatatcggaa caaggcctga ttgtttgcca gatgagacga ttgcttattt
     2701 ggctgagcta tcagagcgca tgcatgtgac agtggagctt gggctgcaaa caacttatga
     2761 agccacctcc cagctgatta atcgggcgca ttcttatgac ttgtataagg aaacggttca
     2821 gcgtctgagg cagtacccta acattaacat tgtgtctcac ttgattaatg gcttgcctgg
     2881 tgaaacccat gagatgatga tcgaaaacgt tagacgctgt gtcacagaca atgatattca
     2941 aggcattaag ctgcatttgc tgcacctgat gaccaatacg cgtatgcaaa gagactatca
     3001 tgagggacgc ttgcagctct tgagtcagaa ggactatgta tcgattatct gtgatcagct
     3061 agaaatcata cctgagcata tcattattca tcgcatcaca ggtgatgcgc ctagggacat
     3121 gctgattggt cccatgtgga gcctgaataa atgggaggtt ttgaatgcga ttgacctaga
     3181 aatggaaaga agaaatagct ggcagggctg taagcttaag ggataatcgg gggaagcaat
     3241 gaaacaaaga ttgatagcag gagaggagct gagcctacca cctgttttaa aaaaactgtt
     3301 acaaaacagt ttggtttatg atagcagtag ctcggcagag gcacgtgttt atgctattga
     3361 taaagggcag ggctattttc taaaaacagc cgctaaaggt aggcttgcca aggaggccgc
     3421 cctaactcgg tattgtcata gtaagggctt agcaacagag gtgcttgatt atatcagcgg
     3481 tgatcaggat tggcttttaa ccgcaaaggt agcaggagag gacgccagtc atattgaata
     3541 tttgtccgat cccaagcgct tatgtcgtat cttagttgat catatgctaa agctgcatag
     3601 cctgtctttg tctgattttc ctgtagctga caaaacgcta gcctatatcg aagctgctga
     3661 ggctggttat caccaagggc ggttcaatca gtgcttttta ccgcctcagc aacggtttca
     3721 gtcccaggag gaggcttaca ggcggattca ggagcttaag ctcttgttac agcatgaaac
     3781 tctgattcat ggggattttt gtttgccaaa tatgatcttg gatcggtggc aatttcagtc
     3841 catgattgat tggggggagg caggaaaaag cgatcgacat attgatcttt tttggctgat
     3901 ctggtcgctt caattcaatc taaaaacaga tcggtataaa gattatgtgc tagattgtta
     3961 cggccgaagg catattgact tagacatact agatggtatc gcggcatttg aagtatttgc
     4021 ttaggaggat aagatgataa agcgtcctat tcatgtatca catgaatttt taaaagaagt
     4081 tttggataag cagagtattg ctgttgatgc tactatggga aatggctatg acactgcctt
     4141 tttagcaagt ctgtcacaaa gggtttatgc ttttgatgtg cagcagcagg cactgaccaa
     4201 gacacaagag cgcttggagc agcaaggctt gactaatgca gagcttattt tagctggaca
     4261 cgagcaggtg gatcaatatg ttaaggagcc cattcgggca gccattttta atctgggcta
     4321 tctacccaat gcagataagt cgttgatcac aaggcctgag acgaccatat tagccctagc
     4381 taaaatactt gatcggcttg agctaggtgg acggattgct atcatggtgt attatggtca
     4441 tgatggcggt agtagggaga aggaagagct tttggactat attggtcagc tcaatcagcg
     4501 ccaggtaaca gcaatgctct atcagccgat caatcagatg aatcagccgc catttttaat
     4561 catgctggaa aaaatagcag ctactgatta agcttcagcc agccttatgt cagggcttag
     4621 actgtctgtg atttctcagg aaaaagaaat aaatcagcaa tctttggcga caattgtgat
     4681 ataatgaagt agtatattat gttttaggag ttatattaat ggaagaccct gtgagtcagc
     4741 ctttattgat tcagttttta ttgttagtca ttctaacctt gttaaatgcc tttttctcag
     4801 ccagtgagat ggctctggta tccttaaatc gctctcgtgt ggagcaaaag gctgccgatg
     4861 gggataagag gtatgatcgc ttgctgcgtg ttttagagca gcccaataac tttttatcga
     4921 ccattcaggt tggtattacc tttattagcc tcttgtcagg ggcgagcctg tcagcctctt
     4981 tagggcaggt tatttctggc tggttaggtg gttctgcgac cgctcaaaca gctggtagca
     5041 ttatttcttt ggtgttcttg acctatgtct cgattgtttt gggagagtta taccccaagc
     5101 ggatagctat gaatctaaaa gacaagcttg ctgtgatttc tgccccagtg atcattatct
     5161 tggggaaatt ggttagtccc tttgtttggc tcttatcggc gtcgacaaat ttactgagcc
     5221 ggattacccc aatgaccttt gatgacgcag atgagcgcat gacgcgtgat gagattgagt
     5281 acatgctgac taacagcgag gcaacgcttg atgccgaaga gattgaaatg ctgcagggga
     5341 ttttctcgct tgatgagatg atggcgcgtg aggtgatggt tccaaggaca gatgccttca
     5401 tgattgacat taacgatgat acgctagaca atatcaagga aatcctaaag cagagcttct
     5461 ctcgtattcc agtttatgat gttgacaagg acaaggtgat cggcttaatt cataccaaaa
     5521 ggcttttaga atcaggcttt cgtcagggct ttgaaaacat cagcatgaga aagcttctgc
     5581 aggagccgct ctttgtacca gaaacgattt ttgtagatga tttgttgagg caattgcgaa
     5641 atactcaaaa ccagatggct atcctacttg atgagtacgg aggggttgca ggtttggtga
     5701 cgcttgagga tttgcttgag gaaatcgttg gtgagattga tgatgagaca gacaaggctg
     5761 agcaatttgt tcatcacatt gatgacaaca cctatattgt cacagggaca atgacgctca
     5821 acgactttaa cgagtatttt gacacagaat tagaaagtga tgatgtcgat accatcgcgg
     5881 gcttttattt gacagggatt ggtaccattc caagtcaaaa ggagaaagag agctttgcct
     5941 gtgatagcaa gcaaaagcat ctggttttgg tcaatgacaa agtaaaggac ggtcgtatca
     6001 ccaaattgaa acttactatt tctaatatag aacagaatat tactgaagac taggcattga
     6061 gcttagtctt tttgatgaaa catgatataa tgaaaacgta aaaccattta caagggtgaa
     6121 ggagacacaa tggttgaagt agattatggg caagtaactg gaatggtgca ttctacagaa
     6181 agctttggtt ctgttgatgg tccggggata cgttttatca tttttttgca gggctgcaag
     6241 atgcgttgcc agtattgcca taatccggac acctgggcta tggaaaccaa tcaatctcaa
     6301 cgccgaaccg ttaatgatgt cctaaaggag gctctgcaat ataggcactt ttgggggaaa
     6361 aagggtggaa tcactgtgtc aggtggtgag gctatgctgc aaatggactt tatcactgcg
     6421 ctctttactg aggccaaaaa gctaggtatc catacaacgc tagatacctg tggctttgcc
     6481 tatcgtccaa cccctgaata ccatgagctg ttagaaacat tattagcagt tactgatttg
     6541 attttgctgg acttaaagga gattgacgag gagcagcata agcttgtcac ccgtcagccc
     6601 aataaaaata tcctgcagtt tgctcgctac ctctctgata ggcaggtgcc cgtctggatt
     6661 cgccatgtct tggtgcctgg cttgacagac attgatgatc acttggtacg cttagatgcg
     6721 tttgtcaaga ccttgagaaa tgtcgacaag tttgaggtac tcccttatca tacgatggga
     6781 gagttcaaat ggcgcgagtt agggattcca taccagcttg agggcgttaa gccaccaacc
     6841 aaggagcggg tggagaatgc caaaaagctg ctgcatacag aatcctatac tgaatacatg
     6901 aaccgtattc atcaatcata ggctaagcta gagttgggaa atgcccagct ttttttggcc
     6961 ccatgtcaac tgtagtgggt gactgataac taagcacgag acgaagctcg ttttctcttg
     7021 tgtgatgtgc aaagcgaggt aaatgggctc tataatttct gtagtgggta aatccaccat
     7081 ggaaattata gagccgtttt tttgctgatg aagcggctgg cttgatgaga ccttcagtgt
     7141 ttttaagcga gctcagacac gtgccaaaaa gtaatccttg aagcattaaa ccaatcaagg
     7201 acagtgtatt gtccccaaat agctgaatag ctcattatag aaggcattgc tttttggact
     7261 ggcttgcctg ttcttgtgtg tttgacagga ctctttaata cctgagattc tgtgccctta
     7321 tgccctttag actcttggcc tgtgactggg gaatcttctt tgattttaga gcctatttct
     7381 gctacaataa gatgaataaa gagaatgagg tagaaacttt atgtcaaaac tattagtttt
     7441 tggtcatcaa aatccagata ctgatgccat cgcatcatcg tatgcttttg actacttagc
     7501 aaaaaaagcc tttgatttgg atacggaggt agtcgctctg ggtgacccaa atgaagaaac
     7561 agcctttgcc cttgactatt ttggggtatc agcaccaaga gtggtgacat cagcaaaagc
     7621 agagggtgct agtcatgtta ttctaacaga ccataacgaa tttccacagt ctatttcgga
     7681 tattcgtgag gttgaggtgt atggtattgt tgaccaccat cgggtggcta attttgagac
     7741 agcaaatccg ctttatatgc gtgtcgaacc tgttggctct gcctcatcta ttgtttaccg
     7801 cctgttcaag gaaaataggg ttgatgtgcc aaaggacatt gcaggcatgc ttttgtctgg
     7861 cttgatttct gataccttgc tgttaaaatc accaacaacg catgcttcag atcatcgtgt
     7921 tgctgcggaa ttagcagagt tagcaggagt taagctagag gaatacggta tggctatgct
     7981 aaaggccgga acaaaccttg caagtaaatc agaagcagaa ttgattgata ttgatgctaa
     8041 gacctttgaa ttaaatggca acgcagttcg tgtagcccag gtcaataccg ttgacattgc
     8101 agaggtgtta gagcgcaagg aggctattga ggccgctatt agagaggtga tggcaagtga
     8161 gggctattct gattttgtct tgatgattac agatattgtt aattcaaatt cagagatttt
     8221 ggcgcttggt gcgaatatgg ataaggttga ggcagccttt agctttaagc ttgaggataa
     8281 tcatgctttc ctagcaggtg ctgtatctcg taaaaagcag gttgtccctc aattaactga
     8341 aagctttgga gcatagagct tgcctgtaga ggggtgttga tttttatcag cagccctttg
     8401 gtctttttgc tataatagta gtatgattac catttttaac cctgataaat taacgcgtca
     8461 gccttttttt caagacctta ttcattacct caatcagcat gatgacgtaa ccctgcgtca
     8521 cattaagcag gccttttctc atgttaaggg gattgataag gcgcttgaag cttacattca
     8581 ggctggctat atctgtcgaa aaaacagacg ctactatctg tgtctgccct tgctagatga
     8641 cctgcagcag gtgacattag aagatctaat ctttgtggat agggcatcag atctatatga
     8701 agctttgatg gccttggtgt ttgagacagt gctgtctaat cagaccaatc aggttttgat
     8761 caaggaaaaa acaaccattg accgagataa gctgacgctt gccaattatt tttaccgctt
     8821 aagaagaggg gaagccctat ctgatgagca attaaggctc tatgccctat taggtgatgt
     8881 gaatcaggac tatgccttga agtacatgac cagctttctt ctaaaatttg ctagaaaaga
     8941 gattgttatg caaaagcgga cagatatttt tgtgaatgcc ttggagcttc taggctatat
     9001 tgaaaaagta gaggccacta aatactgcct gaagctggct tttgataagg agcagctgat
     9061 tttctacgct gattaagagt tgacttgatg aataaaaaat ggcttagacc cacactgtaa
     9121 aacagttgag tctaagccat ttatgcttgc tgagcccttt aagctatgca gcagaggctc
     9181 ttatgtcatt ttgaccatca gatagagaaa ataggatgca ccaataattg agacaagaat
     9241 accggttggt atattgctgc cgacgagata gactcgtccg atagtgtcag ccaagagaag
     9301 cagaatcatg ccgatgaaaa ggctgacagg caggcttaat cggtgatcag ctcccactag
     9361 tcgtttgctg gtatggcctg ctatcagacc aataaaggtg atgtttccga ccaaaataac
     9421 acttagggct gagagaatcg cagatagtgc aagaacaatg gtacggtact gatggagctt
     9481 gaagcctaga gccatgcttg cttcatcatt taatgccatg atgttgagct tataggcttg
     9541 actaaaggct agcagccaag tgatccccaa taagggagca acaatgctta gcttggacca
     9601 atcatcgcct gttagctgcc cgcttagcca atgaatcaca taatccacct tataacggtt
     9661 cacattgccg acaaaggcaa tcatcaggct agatagcatg gttgatagcc ctacgccagt
     9721 gacaatcagc cgaataggat caatatggcc atgacgaagt gagagcaggt agaccaagac
     9781 aatggttgcc attgccccgg atatggtcat aagcggcagc ccttgcctgc tggtcagact
     9841 gttactagtg ctgtaggata tgacaagggt aatagccata ccagcaccag cattaatgcc
     9901 tagtatgcca gaatctgcca gatgatttcg cgttaagctt tgcagcatta agccagaaag
     9961 ggccagtgag ccgccaccga tacaggcagc taaaattctt gggagtctaa tgttggtgat
    10021 gatcaaggcc atatcagcag tggatttacc aaaaagcacc ctgacgacct ccaatggtga
    10081 catgctagat tccccaatag acaaggaaat aatcatcaaa cagaccagtc cagagattag
    10141 tcctagaaat aatgggacgt gtcttttagt agctgtcaaa agcgacctcc ttttctaact
    10201 agccataaaa agcagggcag cccaataaag ctgatcaaag cagatagcgg tgtttcatag
    10261 gggggattga tattccgaca ggcaaagtct acccaaagca taaagctggc tccaagaaga
    10321 gtagctagcg gcaggatcca gcggtaatcc ttagcagtga ctaatgtgat ggcatgaggg
    10381 ataatcaagc cgacaaagga aatgctgccg gctactgcta cagcagcaga agacagaagc
    10441 agcacaagtc caataaagat aaggctaatc aagaaggtgc gttgccctag ggccttggcc
    10501 tgctcttgac ttaagcttaa aatggtcaaa tgataggcta gcagataaga tagggctaag
    10561 ccacagatga tgagtggcgc aacatagcta accatctgcc aattgacccc gatcaatcct
    10621 cccgcctgcc agccaataat ggcattggct aggtgacaat aagttgttat tccttgtccg
    10681 atagctgaca gtagcataga tatcatcgct cctgctaaaa taagcctcat ttgagtgtag
    10741 cccttaccag cttgataggc taggctgaga attaataggg tcgctaagag tgaccctagc
    10801 aaggaaagta atataattgt cgaataatga agatgagggg aaaaagcata gccgatgact
    10861 aatgccagcc cagctccaga gttgattccc agtaagccag gctcggcaat gggatttctg
    10921 gtaatgcctt gcatgatagc tcctgaaaca gcaagtgcag caccaactag agctgctaaa
    10981 atcaagcggg gcaggcgaat gtccaaaata atgctggcct tttgaccctg gtcctgcttt
    11041 ccaagtagaa tatgatagag ctcctgatgt gatagtgaca cagccccaaa cctcagactg
    11101 cagtaaatgg caagcactag agttaagctg ataaaggtta agatcagcca aggaggagct
    11161 gctttagcta gtttaggctt agtatgatgt tgagctgtca tcttaagttt ttattgactt
    11221 gcaccagttg agaggatagc cttttttaga acctcaagct ggtgctccag tgacagtggg
    11281 tctgtgaagt aaaagacatt agcgttgacc ttgatgacat gattgttggt cacagcaggg
    11341 atctgctgcc aaaggtcgct ctcatataag gctgagccgg tttggtcatc ctcagcagca
    11401 acaatcacat aatcaccaat ataatctggt agaacctcct gtgataagga cagatagccc
    11461 tgcttaaaca cctctttttt caccttttcg ggagcatcat aatgtaaggc ctgatgaata
    11521 atttcaccac ctcttcccca gtccttacca aaaaggtaaa tttccttttc atagagcccc
    11581 atgattgtaa aggtagcagc tgatccggtg acttgtttta tttctttttc atagtcactt
    11641 gttttttgtt tccagtcggc caaccattgg tcagtttcct tttccttgtt aaaaatacgg
    11701 ccaaaatcag aaaacacctg caaataatca cgcttgcggt attcaatgga gattagtggt
    11761 gcgatttttg ctagctggtc aatgttttct tctgttgagc caacaacaat gagatcaggc
    11821 tctagtgctg taatagcctc taggtcagta gctgccacct gcttggcttg agtaatgctt
    11881 tttgttaaaa cagggttctt tttgtcgtag gaggtgacac cgaccagatg aaggtctaat
    11941 tttgccaagt aaccagtata tgtagctgct aagctaacca cgcgctttgg cttgacagga
    12001 atgtcaccat aataggtcac tccagcaatt tttggcttgt gggataggct tgctttgctg
    12061 gtgctttctt gttgcttgct ttgacttgag caggcgacta atgtaaaagc tgtcacaaaa
    12121 acagttaaaa taagcagtag ttttttcatg tattctattc tcctagaata aatttatatc
    12181 agctgatagg tcagcaatgt agggcaatga tagagaggat cagtgacgag ctgagccttt
    12241 acttgaaaaa tgtcttgaat catctctggc gtcatcacct ggttgacctc tccagaatat
    12301 ttgatatgtc catttttcat ggcgatcaga tgatccgagt agcgtgctga aagatttaaa
    12361 tcatgaagga ccatcacgat tgtttttcca gagacctgat tgagctcctt tagtaattct
    12421 aaaatatcga gctgatgatt catatctaag taggttgttg gctcatctag aaaaataata
    12481 tcagtatcct gtgctaaggc catagcaatc caggcccttt gacgttggcc gcctgacagg
    12541 gcatcaacag cctgatgagc atagggtgcc atgcttgtga cctccattgc ccagcaaatc
    12601 ttatccttat cagcttgact gagttgtcct aggtaggatt ggtggggata acgcccataa
    12661 gaaaccagct catagacagt agctgtagta gcttcttgca gctgaggtaa aactgctagt
    12721 gttctggcaa cgtccttggt tgctagtcta gcaatggctt gtccatctaa gagaacctgc
    12781 cctgctttga gtggcaatag tcgtgccaga gtctttaaaa gggttgactt cccacagcca
    12841 ttagcaccga tgatggttgt tacctttcct tcgggaatag tgacagataa gttgctgatg
    12901 ataagcgatt gatcatagcc agctgaaatc ctctcagcac tgattgttga catggttttt
    12961 ctcctttcta atagtcaagc aaagccagct agcaaaattc taaggggctg atagcctatg
    13021 aaatgctagt cgcttttttg gtctgactat aatagtgcgc tttctcttaa aagctatccc
    13081 attatagcat agaaaaaagg cctaaaaaag cctttcagaa tctaattact gagtttatgc
    13141 taaaaaagga gccagcttag aatcattatc agtaatctta agaattatta ctgtttagcc
    13201 tgttagacca gtctataggt agctctttgc aatcgctaaa tcacctgcat aggcagtctt
    13261 ttgtcccttg acaatctgat aagcatcagc ccccttgcca gcaataatga gtgcatcctg
    13321 ctcattctga cagcgctcca taccagtctt gattgcttct ttacggtcaa tgataatatc
    13381 aacctcgcgg tgaatatagc tagcaatctc ctctgaaatc agctgtgggt cctcaaaatt
    13441 aggatcatca gcagtcagaa taatacgaac attggggtgc tggttgatga cttgcccaaa
    13501 atcagcccga cggctctcgc ctttattgcc cggtgctcct agaatcaagt aaatctggcc
    13561 tttctggtac tcttcgacaa cagataggag cttttcaagg ctatcaccgt tatgtgcata
    13621 atcaacaaat accttggcct gattggtcat ggttaagacc tccatgcggc cagggacgtt
    13681 tgtcttagca atgccttggc ggatatcctc taggcttgcc cccagtcgaa gacaggctag
    13741 tccagcagcc atagcatttt cttgattgaa gctgccaatt aattgaatcg catagtctcc
    13801 agctaccttg ccggctgctt gaaatgagaa ggcctgccgc tgcagcagcc tattgcaagc
    13861 ccctttgcca taaaaatcat gaggcttatc agccacctgc tctgctagga tattaaaatg
    13921 ctccataccg ctattgacca caacagctcg gctattttcc attaagagcc gcttatggta
    13981 aaaataatcc tcaaagcttg ggtgctcgat tggtccgatg tgatcggggc taatattaag
    14041 aaagacaccg acatcaaagg ttaagccgta gatacgcccg accaagtagg cttgactaga
    14101 gacctccatc accaaatgcg tcatgccatt agccacacac tgagccatca tcgcaaataa
    14161 atcaagactt tcaggtgtgg ttaactgcga tttaaaaaag tgttggccat ctaaggtcgt
    14221 gttcattgta gagagcaggg caggcttatg agattccttt agcatatgat aggcaaagta
    14281 ggcagcagtt gtcttgccct ttgttccggt gaaggctaat agcttgagct tattttgtgg
    14341 gtaatcataa aaggccatcg cagctaggct catagcgtgc ttaatattgt taacaagaat
    14401 aacagggatc cctacctgat agtcaatctc tgaaacatag agtcttagtc ccttggcaat
    14461 ggcctgtctc aaaaagtcag ccttaaaagc tgatccctta gcaaaaaaga gcgtctgctc
    14521 atctgcttgt ctgctgtcgt agctaaggct gtcaaactgt agaccgctat agttaaagtg
    14581 gtagccgtct tgatcaagaa cctctcggaa attatggtcc ttttttaaaa tggttaataa
    14641 gtgctcaatt gttatcatag ccttatttta tccttaatgt tcttgtttta caagtcacaa
    14701 gcaaaagttt ataataaagc tataaaaact aggaagaacg gatatgtcga cagaaaaaaa
    14761 acaattgaca caagaacagc tgatggttca gggagcagcc tggtccaccg caggtaattt
    14821 tattagccga cttttaggcg ttctatatat tattccatgg tacatatgga tggggcagta
    14881 tgcgatacag gcaaatgcgc tctttaatat gggatacaat gtgtatgcct attttttgtt
    14941 gatttcgaca acagggctaa atgttgccat tgctaagcag gtcgctaagt acaactcgat
    15001 gggacagcaa gagcatagct atcagctcat tcgaagcact ctaaaggtta tgctggtatt
    15061 aggcttgatt ttctcagtgc tgatgtatct gggatctccg ctctttgctc gcttgtccgg
    15121 tggtgatgag acccttgtcc cgattatgca tagcttatca ttagctgttt ttgtttttcc
    15181 agtgatgagc gtgattaggg ggatttttca gggctataag gagattaagc cctatgctct
    15241 tagccaaatt gctgagcagc tggttcgtgt gatctggatg cttctaacaa cctttttcat
    15301 catgaaaatg gggtctaagg actatattgc agctgttacg cagtccacct ttgctgcttt
    15361 tattggaatg atagccagta tggcggtgct cttttattat ttctggacgc agggcctttt
    15421 aaaggctatt tttaccaaga cagagcatgc gattcctatt gacatcaagg gcttgcttat
    15481 tgaaacgtta aaggagtcga ttccctttat tattacagga agtgcgattc aggcctttca
    15541 gctccttgat cagtggacct ttgtcaatac gatgactctg tttaccagct acacgcgttc
    15601 tcagctctgg gtgctgtttg ggtattttaa cgccaaccct gctaaaatca ccatggtgct
    15661 cattgcagta gccgcttcaa ttggtagtgt tggtattgcc ttattgacag aaaattacat
    15721 taaaaaggac atgcgagcag cagggcgcct gatcattaac aacattgaaa tgctgctgat
    15781 gtttttattg cctgctctga caggagctat tatactggca aggcctcttt atacggtttt
    15841 ttacggtagt agcgagggac aggctgttag gctgtttgtt gctgtgcttt gccttaccct
    15901 attgatggcc ttgtatacgc ttttttctcc gatgctgcag gccctgtttg aaaaccgtaa
    15961 ggccatctat tattttgctt atggtgtttt tgtcaagctg gttttgcagg ttcctttgat
    16021 ctatctgttt catgcttatg gtcctttgtt agctacgacc cttggcttgc tagtgcctat
    16081 ctatctcatg taccgtcgtc tacatcaggt cacacgattt aaccgtaagc tgctgcataa
    16141 gcgtatatta ctaacggtga ttgagacagc attgatgggc ctgattgtgc tactagctaa
    16201 ctggtttttg ggctatttgt ttaagccgac aggcagattg actagcctgc tttacttagt
    16261 gattattggt ggcttgggaa tgggtgttta cgcctacatg acgttattga cgcgtcagct
    16321 ggacaaatta attggcagca gagcagctag gtatcgccaa aaattgggac tttgacaccc
    16381 aagatcaagg cagctgaagc aggcagctag ctgatcagat tcttgctttt atcatttcaa
    16441 ccggatctga aaaaagtaag caaggttttc aattttttgg tataatagca aaagtgtaaa
    16501 aaataaagaa ggaagtacgt catcatggga aaatgtcagg ttatttcgca tccacttatt
    16561 cagcataagc tatcaatcct gcgtcgtcag gatacctcaa ccaaggattt tagagagctg
    16621 gtcaatgaaa ttgcaatgct tatgggctac gaggtttctc gtgacttgcc attagaggat
    16681 gttgagattc aaacaccggt tgccaagacg gttcaaaagc agttagcagg taaaaaatta
    16741 gcaattgttc cgattcttag agctggtatt ggtatggtgg atggctttct tagtcttgtg
    16801 ccagctgcca aggttggtca catcggtatg tatcgtaacg aggagacctt ggagccggtt
    16861 gaatatttgg tgaagctgcc agaggatatt gatcagcgcc aaatttttat tgttgatccg
    16921 atgctggcta ctggcggctc tgctattctt gcagtggatt cactgaaaaa gcgtggggct
    16981 gctaatatta agtttgtgtg tctggtagca gcaccagaag gggttaaaaa gcttcaggag
    17041 gctcacccag atgttgacat ttataccgca gcccttgatg aaagattaaa tgatcatggc
    17101 tacattgttc ctggtcttgg agatgctggt gatcgcttat ttggtaccaa gtaaaaggct
    17161 acaggctttg gttgtgctag gctctgcttg ctagaggcta gcctgctaaa gctaataaga
    17221 ctttctagtt taggctggaa ggtttttaaa agcaagttta tcatttgacc ttttttgacc
    17281 aagagattat aataaggtca atcattataa aaagatgtgt ttgactgcct gtcactgcat
    17341 gaggcagagt ggtgttagac agtcacgata gattggagat ttttatgatt cctgtagtta
    17401 ttgaacaaac cagtcgtgga gagcgttctt atgacattta ttcacgtctg ttaaaggacc
    17461 gtattatcat gctgactggt ccagtagagg ataatatggc aaactctgtt attgcgcagc
    17521 tcttgttttt agatgcccaa gacaacacaa aagatattta cctctatgtg aataccccag
    17581 gaggctctgt atcagctggt ttagctattg ttgatacgat gaactttatt aaggcagatg
    17641 tgcaaaccat tgttatgggt atggctgctt ctatgggaac cgttattgct tcatcaggtg
    17701 caaagggcaa gcgctttatg cttccaaatg cagaatatat gattcaccag cctatgggag
    17761 gcacaggagg tggtacgcag cagacggata tggccattgc tgctgagcat ttattaaaga
    17821 cacgtcaccg cctggaaaag attttggcac aaaatgccgg taaaacgatc aaacaaatcc
    17881 ataaggacgc tgagcgtgat tattggatga gcgcagaaga aaccctagcc tatggcttta
    17941 ttgatgaaat catggaaaat aatgagctag cttagagagc ttagtaaaat agcttaacag
    18001 cttctgaaac aaattgtttc aggggctttt tgcatgctaa agagggctat cttccttaaa
    18061 attatggtat aattaaccta tgctaatcat aaatgaagaa ttgtttgcca ttgaaaaggc
    18121 tattgagcag ctggttcagg atattaggac aagcagccag tatcaggcct atgccttggc
    18181 taaaaaggct tttgaggcag atttggccct acagaccgag ttagccttat ttgaggagct
    18241 taagcaggat tatgagctta ggcaggactt gcttaagttg tgtccagatg ctagagcgtt
    18301 gcgctgccaa ttacttcatc aaaagcgcca gcttgacctg catccattgg ttgctgatct
    18361 gcgcttggca caggttgatt tgcaggaggt tttggcgacg atttcgacag ctattgcaga
    18421 agcagtgtct gaggatattc ttgtcgacac aggacttccc ttggcgacaa atagacctcg
    18481 acatgagctt ggaccgtatc aaaatataaa agaaaagagt acctaaatgt ttcaaaaaca
    18541 gcagagaatt gggctggtta tctacctgta ttacaatcga gacgctagaa aagtgatgaa
    18601 atatggtgac ttgtactacc attccaggcg ttctcgatac cttgttattt acatcaataa
    18661 agaggacatg gaagaaaagc taaaggacat tagtcggcta acatttgtca aagaggtgaa
    18721 ggtatcagcc tttgatgaca ttgattgtga ttttgttggg aatttacatc gtgagcctct
    18781 agagcctcaa gccctacctg agcagggcta agtaggcctg atcctgtctt atatagcatg
    18841 tcttagctca tcaattgctc aaagctgatg gatcagccct gctggcttgc ttaggcaaag
    18901 aaaataagag ctgagacgat tgtcatttat cgagtggctg ctcataggct ttgaggtgtg
    18961 aggcacaagt cttaggctgc tgctttgagg gctggctttt tattcctatc gcctaaaagg
    19021 cagcacaaaa aggctttttt ctgatctggc actgcccaat gaattggcag tgctttttca
    19081 ggcaaatttt ggtaaaatag aggtaacgat aaacaaagga ataaagatga ctagaggaaa
    19141 attaataacg tttgaaggtc cagacggagc aggaaaaaca acggtgctgg aaagactggt
    19201 gccactctta caggcagctc taggacaaac cattgtaaca acgagagagc ctggaggcgt
    19261 tgcgattgct gagaagattc gtcagctgat cttagatgtc agtcacacga ccatggacga
    19321 taaaacagag ctgctgctct atattgcagc aagaaggcag catttggttg aaaagatcat
    19381 gccagctctt gagtcaggac acttggtttt ggtggatcgt tttattgaca gttcagttgc
    19441 ttatcaaggc gccggaagag ggctggataa gcaagccatt caatggctca atcattttgc
    19501 aacagatggt gttgaccctg atttaaccct gtattttgat gtgccctcag agcttggatt
    19561 ggcaaggatt gcacaaaata ctgagcgaga gatcaatcgt cttgatcttg agcaattaga
    19621 tttgcaccag cgtgttcgta agggctatct ggagctggct ttggaaaatc cccagcgtat
    19681 tgtcaagatt gatgcatcac aggacttaga aagcgttgtg tcagcggctt tagctgccat
    19741 tatcacacac agtcaagcat agcaggaggt taggaatgga tttggctcaa aaggctccta
    19801 gggtctatca ggcctttcaa gagattttgc aaaaaaaacg tctaaatcat gcctacctct
    19861 tttcaggtga ttttgccaat tttgacatgg ctcttttttt agccaagact cttttttgcg
    19921 aacaaaaaag aggcaatgct ccttgtcatc actgtcgtgc ttgccagctg attgagcaca
    19981 atgacttttc agatgtcacc atcttagagc ctgtcggtca gcttatcaag actgataccg
    20041 tcaaagaaat gatgacaaat ttttcgcaga ccggctatga gggcaggcgg caggttttta
    20101 tcattaagga ttgtgataag atgcatgtca atgcagctaa cagcatttta aaatatatag
    20161 aagagccaca aggggattgc tatatgtttt tactaacgaa tgatgacaat caggtcctac
    20221 caacgatcaa gagccgtaca caggtttttc actttccaaa agatgagcac tacctctctg
    20281 agctggccca aaaaaagggg cttttgaaac atcaagcaga cctcttagcc agattagcag
    20341 ccaatgccca gcagcttacc gctttttctg aaaacaccag gctgttggag ctgatggcgc
    20401 aggctgagcg ttttgtttcc atctggtttc aggataagga acaggcttat ctggagctta
    20461 atcgcttggt tcagctagca gaggaaaaag aggagcagga catggcacta actcttttaa
    20521 ccttaatctt ggcgaaggac tacagtcgac aaaatgcttt tacctatctg gaggctgttt
    20581 atcaggctag acttatgtgg caaagcaatg tcagctttca aaatacgtta gaatatatgg
    20641 tgatttcatg ataagtacga ttggaattaa atattgtgac acctgctctg tcaggtacgt
    20701 tcaaaccgat caggcctttc ctgtgcaaac caagcttgtc atatctgatg gcaagggcag
    20761 tcgattggca gtggtcaatt ctccgataaa aagcttttgt aaggacgacc tgccaaagga
    20821 tatgccctct gttttgagac ctgccaatga catggactac aaggcttacc agcaaaacct
    20881 tcagctagca gcccagtcaa agcaaaaagt agcagagatg attgacagaa atggcttaga
    20941 catgaccttg gttgacattg ttttctccct tgagagacgt tatgttttga ttacctttac
    21001 cgctcaggag cgtgttgatt ttcgccagct cctcaaggat ttggctgcct atttcaagac
    21061 aaggattgag ctgcgtcaga ttaatagtcg tgaggaggca agggtttatg gagggctggg
    21121 tccctgtggt cgcccactat gctgttcaag ctttttagga gagtttcctc cagtctcaat
    21181 caaaatgcta aaacatcaag ggctgtcctt gcattcggca aagtctttgg gctgctgcgg
    21241 tcgcttgctg tgctgcctac aatatgagga cgatttttat caagaaagta agaaaaaatt
    21301 tcctgattat ggtactatag taagaacagc gcagggacca ggtgaggttg caggaattga
    21361 tctttttaca gataccattc aggttcgctt taaggaccag ctggccttgg taacctatgc
    21421 tttagaggag gttaaagtta gtgaataaaa aagaactgtt tgacgctttt gatggctttt
    21481 cacaaaacct gatggtgact ttagctgaaa ttgaagcaat gaaaaagcag gtccaaggac
    21541 tcgtagagga aaatactatc cttaggcttg aaaacaccaa attacgtgag cgcttgagtc
    21601 aattggagca cgaaaatctg gccaagacct cttctaagca gggcaaggac cacttggagg
    21661 gcatttatga tgagggcttt catatctgca attttttcta tgggcaacgt cgtgaaaatg
    21721 atgaagagtg tatgttttgt cgagagctat tagatagaaa gtagagtcat gcaaatccaa
    21781 aagagcttca aggaagaaaa agagtcaggg gttctctatc tggtgcctac ccctattggt
    21841 aacctagagg atatgacctt tagagcggtc aatgttctaa aagaggtgga tattatctgt
    21901 gcagaggata cgagaaatac tggtctgttg ctcaagcatt ttgggataaa gacaaagcag
    21961 gtaagctttc atgagcataa tgcttatgat aaaattccag atttgctgga cctgttgttg
    22021 gctggaaggt cattggctca ggtctccgat gctggtatgc cctctatttc agatcctggt
    22081 catgagctag tcagagcagc tattgatcga gatattactg ttgttgcttt gccgggtgct
    22141 tctgcgggca ttaccggcct cattgctagt ggcttggcgc cccagcccca tctgttttat
    22201 ggctttttgc caagaaaagc tgggcagcaa agggcatttt tgatgactaa ggcagattat
    22261 ccagagactc aaatctttta tgaatctcct tatcgtgtta aggatacgct aacaaacctg
    22321 ctggcctgct atggggatcg ccaggtggtg ctggtgagag agttaaccaa gctttttgag
    22381 gaataccagc gtggtcagat ttcagaggtc ttgacctatc tagcagacca tccactcaag
    22441 ggtgagtgtc tattgattgt ggcaggtgcc aatcaagctg acgcatcaga gcctgctgag
    22501 gatttggatc tgctagcact tgttcaacag gctattgctg ctggcatgaa gcctaatcag
    22561 gcgatcaaga caatcgccaa agactataag gtgaatcgcc aagagctcta tcagcaattt
    22621 catgggcttg gctagactgg cttttaatcc ggactagtcg cctgattgag agaatctcta
    22681 gtaggccaag caaaggagag gtactcaagt aagggctaat agctgtcttt tgcacttctg
    22741 agaattgtca ttaatgtaag cagatagatt tgtctgcaca ctaagagagc tagtcagttc
    22801 tctttttttg gcttcttgtc aactttaggg gggtgactga taactagtac ctagtgagga
    22861 ccagactggt gctttttttg tgttgttaat agcaatgaga agcttgcttt taatgttttt
    22921 aaggttccta aagccacagg cttgtcgctt cacgccttcc cttaatggtc actttgcagt
    22981 cttaaacgaa aaaaatgctc ccatttagga cgtttcaacg actgtttagg atatggagga
    23041 atgttttaca aaaaaagcgt tatactaaat atgtcaaggt tgcaactgga caacatcgat
    23101 ttttagggag tatttgcaat caatacaata atttgacgta atggctacag aaatgcttgc
    23161 tagctttgaa ggaggaaaaa ataattgggc tgccaatgtg tcaggtgtga ttggagcagg
    23221 aagtgcaggc gcagcacttg gatttccagt atgtggagta gcttgtggat ctattggtgt
    23281 cacaggaggc ttttagaaat gagaaaaaca gaaagattct gagtttggaa ccttgtttta
    23341 ggaggataat agaaatggaa cattatagag cattagcaat aagtgaaatg caagatattt
    23401 caggaggaaa tgcagcaggt aatgctgtta tcgggggatt aggaggtctc aagacaggaa
    23461 ttacattttg caaaatacct catccggtgc taaaaggagt atgtatagac ggctttactg
    23521 ctttaggagc atgcttggca tataaggtaa attagatgtt attgattact ttttcaggtc
    23581 tttatgcttt aatttttatc tatatactgg ttgacagtgc taagaggggc aaagaagggg
    23641 cttcttactt tattttttta attttttatt tcttatcgac tactataagc aatgtaaatc
    23701 ttatatccct tgtgacctta ctatgttttt tagctattta tatagaaaaa aggtaaatta
    23761 agttttgtat ggttcgttta gatacttttt caacagttta gggagtattt gtaatcaatc
    23821 agaaatgctg gtaaatgctg aaggtcggct atggatacgc actggaggtg taagaaacat
    23881 cgatgctggt acttaaaagt agcttggtgt cagatagtga gtggcagtga gggttcatac
    23941 caaaatggtc attaaatagt gattgatagc tggtgaaggc aataaataag accaaaataa
    24001 ttcttctcat tctaccaata attgcttttt ttattcggct gggtgatcta ttcttggttg
    24061 agggatagca aagtccttac ctttacctta tgggctcttt gggggttatc atataaggga
    24121 gtaagcctgg ttaagagagt tttagcgctt taaaattgta aaatcagatt atttaatgta
    24181 tactagagga aataagatga ataaagacgg aaggtcaata caatgataat caaaaaactt
    24241 tcagtaatag ctcttacgag tctatcctta atcagcctat cagcttgtcg tcaacagaat
    24301 caggctctag gtcaaaatgg cagtgctcag aatcatagga aggcaagtgt ttcagaggac
    24361 aaggccaagg aacttgcctt taaggacgcc tcaatcacag cagctgacgc tcaaaggctc
    24421 aagctgacga aagaaacaga cgatggtaga gtggtctatg atattgagtt tgatgctaag
    24481 gatcaggagt atagctatac cattgacgct aataccggtg agatcctaga aaaatcctct
    24541 gagccaatca ctgaggctcc tgcttcagct caagcagctg gtggtcaggc tgatcaagca
    24601 gctggcattt cagaggacaa ggccaaggag cttgctttta aggacgcctc aatcacagca
    24661 gctgacgccc aaaggctaaa gctgacgaaa gaaacagacg acggtagggt ggtctacgat
    24721 attgagtttg acgccaagga tcaggagtac agctatacta ttgatgctaa tagtggagat
    24781 attttagaaa agtcctctga gcctgtttac gattaaaaag ctatcaccgc ttatgtgata
    24841 aaagcctgta acattcctaa gcctttatat gctaaaaggg cttaggtttt ttgttgttcc
    24901 ttgttgtgcc tgatagagct ggagcttgtt ggcagccatt taggcgctag cctatagccc
    24961 gcctttgttg ctggtatttg gctgtgataa gggctgttta gttgaaatga taggcattat
    25021 cagcttagga tttggcagag tgatactttt atgactagaa ggataggcta tgggctgtaa
    25081 atgttgtata atagagtaga aagcgcttgc tatgattgag agagcctatc tcagcagcga
    25141 tagaatggag gacacatggg aactgaaacc tatattatgg ctattgatca gggcacaacg
    25201 agctctcgtg ccattatttt caataagaaa ggagaagcgc tggttagtag tcaaaaggaa
    25261 tttccacagc tttttccaca ggctggctgg gttgagcaca acgccaatca catttggaat
    25321 ttggtgcagt ctgttattgc agacgccttt atcgagtctg gtataaagcc agagcaaata
    25381 gaagctatag gcattaccaa ccagcgtgaa acaacggtag tctgggacaa acagacaggt
    25441 ctgcccatct ataatgctat tgtgtggcaa tctagacaaa cagcctccat tgcagagcag
    25501 ctaaagcgtg atggctatac caaaatgatc catgaaaaaa caggcttggt tatagatgct
    25561 tatttttctg cgaccaagct cagatggctt cttgatcatg ttccgggggc tcaagagcga
    25621 gctgaaaggg gagaattatt atttggcacg attgacacct ggctggtttg gaagctaacg
    25681 gacggggcgg tacatgtgac ggattattct aatgcagcac gtaccatgct atacaatatc
    25741 aaagagctaa aatgggacga tgagatattg gccttgctga atatccctaa ggccatgctt
    25801 cctgaggtca ggtctaattc ggaaatttat ggtaaaacgg cttcttttca tttttacgga
    25861 ggagaggtag ctattgctgg catggcaggt gatcagcagg cagccctatt tgggcaactg
    25921 gcctttgagc ctggtatggt aaaaaatacc tatggcacag gctcttttat catcatgaat
    25981 actggtcaag aggctcaatt atccagcagc aacctgctaa caacgattgg atatggtatt
    26041 aatggcaagg tttattatgc cttagaaggg tctatcttta ttgctggctc tgctgtgcaa
    26101 tggctacgag atggcttgcg aatgataaaa acctcttttg agtctgaaca gctagccttg
    26161 gcttcaacca atgctgatga ggtatatgtt gtaccagcct ttacaggtct tggcgctcct
    26221 tattgggatt ccaatgcacg cggctcagta tttggcttaa cgcgtggaac aacaaaagag
    26281 gattttgtta aggctaccct acagtctatt gcttatcagg tcagagatgt gattgatacc
    26341 atgcaggtgg actcagggat cactatccag caattacgtg ttgatggcgg agcggctatg
    26401 aataacatgc tcatgcagtt tcaggcagat attttaggga ttgatattgc tcgtgctgaa
    26461 aatcttgaaa ccacagctct aggagcagcc tttttagccg ggcttgctgt aggctactgg
    26521 aaggacatgg agacactaaa gcaattaaat gctacaggtc agctgtttaa agcaagcatg
    26581 agtgagtctc gccgagaaaa gttatatcaa ggctggaaaa gagctgtcaa agccacacag
    26641 ttttttgcag aggagctgta agaatcaagc cttttaaaga aacagagtcc catagctagg
    26701 tctagttttg aacactagac tgtgtgatac ttggtctttt atatcctaag agtgactttt
    26761 ataatgataa tgtagacggt aaacagcgtc atgctgttca atgactgata acagactaat
    26821 taacggaggt taagatgaaa tttttcttag acacagcaaa tgtagaggca attcgtgcga
    26881 ttaatgagct tggtgttgtg gacggtgtta ccacaaaccc tagcattatc tcgcgtgagg
    26941 gtcgtgattt tgagacagtt atcaaggaaa tctgtgagat tgtggacggc cctatcagtg
    27001 cagaggtcac cggactaacc gcagaggaaa tgattgcaga ggctaggaac attgccaagt
    27061 ggcatgacaa tgtggtcgtg aaaattccga tgacgacaga gggcttaaaa gcaactaatg
    27121 tcttgtcaca agaaggcatc aaaacaaatg tgacgcttat ttttacagtt agtcagggac
    27181 taatggccat gaaggctggt gcgacctata tcagtccatt tattggtcgc ttagaggata
    27241 ttggagcaga tccttatcag cttattagtg atttgcgtgg gatcattgat ttgtatggct
    27301 tccaagcaga aatcatcgca gccagcattc ggacagctgc ccatgttgaa gctgttgcac
    27361 agctaggggc acacattgca accattccag atccattatt tgcgaagatg actgagcacc
    27421 cattgacaac aaatggctta aagaccttta tggaggattg ggcttccttt aaaaaatagg
    27481 ctaagagcat agagctctcc ttatattcta atgtggctgt agcggttagt ttgggattag
    27541 ctatttgtag gtggcaggat cagctggtgc tttgctgttg cgctagaatt aacaggcagc
    27601 tggcgcttac tgtagccaaa gggaggtacc aaagaggaat gcttgcttag ctggcaacag
    27661 ctaggcttgc tttttcttat gagcataggt gctctatcta agacagctgt caatcacaaa
    27721 aagctaggaa cagcaatgct tattgctaga taagaattta aggactttat aggattttgt
    27781 taaaaatcag tttactttta tgttacaata gacaatggaa aacgtttaat ttttagttgt
    27841 aatacacaga gaggttttac ttatgacatt tgatgcaatt gatcagctgg cagttaatac
    27901 tgttcgtact ctatcaatgg acgctattca agcagcaaat tctgggcatc caggtttgcc
    27961 gatgggggcg gcgccgatgg cttatgtgct atggaatcat gttatgacag tcaatccaaa
    28021 gacaagccgc cgttggtcaa atagagaccg ctttatccta tcagcaggtc atggtagtgc
    28081 catgctttac agcctgttgc acctagcagg ctatgatgtg tctattgagg atcttaagaa
    28141 cttccgtcaa tggggctcta aaacaccagg tcacccagag gtcaatcata cagatggcgt
    28201 tgaggcaacc acagggcctt taggacaagg agttgccaat gcagttggta tggctatggc
    28261 agaggcacac ttagcagcta agttcaatag acctggcttt gatattgtag accactatac
    28321 ctatgctcta aatggtgacg gagaccttat ggagggtgtc agtcaggagg cagccagtct
    28381 ggcaggtcac ttgaagcttg gtaagcttgt cttgctatat gattcaaacg atatttcgct
    28441 tgatggccca acctcaatgg ccttcacaga agacgtcaag gggcgttttg aagcttacgg
    28501 ctggcagcat atccttgtta aagacggcaa cgacctagag gccattgcta aagctatcga
    28561 ggaagctaag gcagagactg aaaagccaac cattattgaa gtaaagacaa tcattggctt
    28621 tggtgctgaa aagcaaggaa cttcagctgt tcatggggct ccgcttggtg cagaaggcat
    28681 tgcctttgct aagaaatctt atcaatggac ccatgctgat tttgaggtgc cgcaagaggt
    28741 gactgagcgc tttagacaag gccttcaggc gcgtggtgag caggctgagc aggcatggaa
    28801 tgacctattt gcagcttatg aagcagcata ccctgagtta gcagccgaat acaaaaaagc
    28861 ctttgctaat gaggcggcag aggttgagtt gcaagctcac gagcttggca cagcagtagc
    28921 cagtcgtgtt tctagccagc aggctatcca acaaatctct gagcaggtgc cagccttctg
    28981 gggaggctca gctgaccttt ctgcctctaa caataccatg gttaaggctg agacagactt
    29041 ccagccgggt cattatgctg gtcgtaacat ctggtttggc gtacgcgaat ttgcaatggc
    29101 agcagcgatg aacggtattg cccttcatgg tggaacacgt gtttatggcg gaaccttctt
    29161 tgtcttttca aactacctat tgccagcggt tcgtatggca gccttgcagc agctaccaac
    29221 ggtttatgtc atgacgcatg attctatcgc ggttggtgaa gatggtccga cccatgagcc
    29281 aatcgagcag ctagctagtg ttcgatcaat gccaaatctg aacgttattc gtccagctga
    29341 cggcaatgaa acaaacgctg cttggaagcg tgcgatcgct gagacagacc gtccgacaat
    29401 gcttgtctta acacgtcaaa accttcctgt acttgaaggt actaaggaat tggcagaaga
    29461 tggccttaat aagggagctt atatcctgtc agaggcaaag ggtgaccttg atgggattat
    29521 cattgcaacc ggctctgaag tcaagctagc aatggatact caagccgctc ttgcagcaga
    29581 tggtatccat gtgcgtgtgg tatcaatgcc atcacaaaat atctttgatg agcagccagc
    29641 ttcctacaag gaggaaatcc taccagcagc agtgacaaaa cgtctagcta ttgaagcagg
    29701 ctcaagcttt ggctgggcaa aatacgttgg ccttgcaggg aaaacactga ccattgatac
    29761 atggggagct tctgcaccgg gcaatcgtat ctttgaagaa tatggcttta cagtagagca
    29821 tgctactgaa ttgtacaaat ccttatcata agtgattaag ctggagcagg ccttatctag
    29881 gcttgctttc ggcattatta gacaaaaaaa cgcatgatgt tcaacccttt ttagggagga
    29941 cgtcatgcgt ttttgtttca gatttaatag tgctactgct cagccttgca gatctatccc
    30001 gagttgctag aagctattgt caaatagctg gcttagcttt tctttctttt tagggttagc
    30061 agacctgcgc tagcgatgac gctaagagct gccagactaa agaatggatg gcttgcctct
    30121 cctgtagctg gtaggactgc ttttttgctt ggtgttgact gaggtgctgg tgccttaggg
    30181 ctagctgact gctctgaagc ctttggagct ttcggtgcag gagccttttc aggagcctgt
    30241 ggcttctctg gcatttttgg tgattctggt gcctttggaa ctgatggctt ggtatccttt
    30301 ccttggtcac cctttggctg ttgctcacca ttttcaccgc gttgaccttg ctcgcctttt
    30361 tcgccacgtt gaccttggtc gcctttttca ccgcgttgac cttggtcgcc tttttcgcca
    30421 cgttgacctt ggtcgccttt ttcaccgcgc tgaccttggt cgcctttttc gccgcgttga
    30481 ccttgctcgc ctttttcacc gcgtggccct tgctcgcctt tttcaccgcg t
//
LOCUS       DARYNN010000025        30363 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.025, whole genome shotgun sequence.
ACCESSION   DARYNN010000025 DARYNN010000000
VERSION     DARYNN010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30363)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30363)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30363
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.025"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(109..792)
                     /locus_tag="TVB59_001057"
     CDS             complement(109..792)
                     /locus_tag="TVB59_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HEL1009958.1"
                     /translation="MLLDVVIQFRDRRSTITIDTPSTCPHCGRTMSPQHVGESKSSDN
                     ESYSYQGHFSVIFRCSFDDCLKYFAVEYIHDQIGKGSAVAYFYRPPIRVNLPENVDKV
                     SPAFVEIYSQATIAEQEKLDQIAGVGYRKAAEFLIKDYTISKNPDDSDNIKQIMLGKV
                     ISDYLSDFPKLQALSRSVAWIGNDETHYVRRHNNKDLQDLKRFILAAAQFVAADYDAD
                     DALSFTSTD"
     gene            850..1038
                     /locus_tag="TVB59_001058"
     CDS             850..1038
                     /locus_tag="TVB59_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009959.1"
                     /translation="MEETASVNVTVKINNITEFSTLVEKFNEKARELEAISHELMRFK
                     FQGEIESRALSDNANEIE"
     gene            complement(1012..1479)
                     /locus_tag="TVB59_001059"
     CDS             complement(1012..1479)
                     /locus_tag="TVB59_001059"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009960.1"
                     /translation="MDLNQVRLLEACHRYLVDRVHIDIKENMLNDKLVFEFNGDFVTF
                     NTYQEVGHCCFYEYELGSYEELENHRSIDVTEILSILNLKSGQIGTLSMLTDITRVRA
                     YIFKLLSQADFAKFEKEIKNTNFAYNFRYVENYSYLPCVKIDKDKLFNFVSII"
     gene            1553..1741
                     /locus_tag="TVB59_001060"
     CDS             1553..1741
                     /locus_tag="TVB59_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1009961.1"
                     /translation="MQILLYKLRKEKRISQEEMSKVINKSSNTYRDKELGKRDFTQSE
                     MFKIANFFHKELGEIFTP"
     gene            1792..2508
                     /locus_tag="TVB59_001061"
     CDS             1792..2508
                     /locus_tag="TVB59_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HEL1009962.1"
                     /translation="MNQLINITLNENQEPVVSGRDLHKVLEIKTAYKDWFPRMAEYGF
                     EEGQDFSSFLSKSTGGRPSQDHVLKLDMAKEIAMLQRNEKSKQVRKYFIQIEKDFNSP
                     EKIMARALLMADKKVHKLEAQIEADRPKVLFADAVSASKSSCLIGELAKILKQNGINI
                     GQNKLFQWLRTNGYLISRRGESWNQPTQKSMQLGLFELKKTAINHSDGHTTTNVTPKV
                     TGKGQQYFINKFLNQEYLPV"
     gene            complement(2663..2878)
                     /locus_tag="TVB59_001062"
     CDS             complement(2663..2878)
                     /locus_tag="TVB59_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009963.1"
                     /translation="MVDKYIPGRYIQREIDEIIELVRDRSKFEPVRVREVQEHIQKIL
                     IQHEAEILARLEENQDQKASENSNDIF"
     gene            3067..3357
                     /locus_tag="TVB59_001063"
     CDS             3067..3357
                     /locus_tag="TVB59_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009964.1"
                     /translation="MAIEVFGPDFRKELLADLISLNREALKIAQFENSKSIEWVTMKR
                     LEKETGWGRTKLTQWREQGKFNFKRSSENGKVLYDLADVNRFLRTSGYEKGA"
     gene            3359..3553
                     /locus_tag="TVB59_001064"
     CDS             3359..3553
                     /locus_tag="TVB59_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009965.1"
                     /translation="MNKLELFLLAATVILAIIARIQYEVIKKHNSPENKRKIFREVAL
                     ENSKRWSEKRSRGEVEKCLL"
     gene            3688..3867
                     /locus_tag="TVB59_001065"
     CDS             3688..3867
                     /locus_tag="TVB59_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009966.1"
                     /translation="MTTTKKLGRPTSNPKSHSKRLRMTDEEVQKLEYCTKQTGKTQTD
                     VLMLGLDKVYQELKK"
     gene            4040..4312
                     /locus_tag="TVB59_001066"
     CDS             4040..4312
                     /locus_tag="TVB59_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009967.1"
                     /translation="MDNSKLANHQKVTVVCTDFNVYLNGIRLTGARPETAKLAERCGE
                     KLITLSLVVTDFDDHRTPKMADMAKEAEMANKTLDWEKKHFYKSNK"
     gene            complement(4302..4682)
                     /locus_tag="TVB59_001067"
     CDS             complement(4302..4682)
                     /locus_tag="TVB59_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009968.1"
                     /translation="MIDYYSLYKNSLEAIGYHKLDTGVDLLQYLIATEEGKRIYSQYP
                     YREVEEIIFYTLDCLIQQDLVTATEMPRLDRRIYTIDGLTPKGMYFLGYIGQVETEVI
                     EWLNEFGVSQNPESIYNALRYIIY"
     gene            4738..5181
                     /locus_tag="TVB59_001068"
     CDS             4738..5181
                     /locus_tag="TVB59_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001074391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009969.1"
                     /translation="MAKTYTLTEEELNELVAERMKQAKEKRTPQGLFKDVSFDDELIP
                     INEKYPKVLKKLNRERAYKPEKHVFNQTPKVFGVDNDISYSKITTHDVHNHIRLLVLN
                     VFGKSQNKEVLPEEYDQAIELYKELKEWFVSSYDKRLEGLVLEDD"
     gene            5298..6110
                     /locus_tag="TVB59_001069"
     CDS             5298..6110
                     /locus_tag="TVB59_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017285243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HEL1009970.1"
                     /translation="MGKEKTKIYFWLKFDKKFFENIFIKRLKKMAGGDTMTVLYIRLM
                     LESLETDCILYYEGYFENLVEELAIKLEVSEDDINMTLAYFTKCGLIQIDGSGNAQMP
                     QAKAMLESETNWAKYKRETRKIGQIPTNVQPMSNQCPTEIEIEKDKKKDINIDIKSEV
                     EEEIKEISTADENSLKIISDYFQQEIGILSPNQFEQLSDYITITKMEVDVVKSAITRA
                     ADNSKRSFGYVNSILRNWRQNGITTMVKVKEESRNFKARKAKQEEVSEYDTW"
     gene            6097..6879
                     /locus_tag="TVB59_001070"
     CDS             6097..6879
                     /locus_tag="TVB59_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEL1009971.1"
                     /translation="MTLGDNNALAKIAVAYQKNVKKESTVCQKHGCIYITILKTGLTV
                     CPMCHKEDLESQNELHVQKQYERELENKRLYYLKKLSIMDDELENASFDNFRVITPKQ
                     QEVLSWAKSMANYWYTGGKGNIIMTGKAGRGKSHLAYSIIRGLSDETKKLGLLVNITD
                     LLSEIKRDFSQEAFWLDKLKNVDYLVLDDLGAEKVSDWSTSIIYSLLNKRTNTIITTN
                     LTPVEIRKNYGERIASRIRKGCAKSHIMDFAGLEDERIKLWN"
     gene            7016..7222
                     /locus_tag="TVB59_001071"
     CDS             7016..7222
                     /locus_tag="TVB59_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009972.1"
                     /translation="MTPEEAEKAKIRAKQEIEVFSIYLEQAIDTFGSMLSPQEVFLAA
                     GFAYLGAGQTDIHAAVEGLYEQVR"
     gene            7384..8310
                     /locus_tag="TVB59_001072"
     CDS             7384..8310
                     /locus_tag="TVB59_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HEL1009973.1"
                     /translation="MANQLSTYTHKQFFNAPTIQKAFDDVWKGAGTQFAVSILSVLQG
                     SKSLKSASNESIYAAAMKAAVLNLPIEPSLGRAYLVPYKGQAQFQLGYKGLIELAQRS
                     GQYKNINAGIVYKSQLISYNPLFEELILDFSKPQDEIVGYFAAFKLLNGFEKVSFWTV
                     EKVTAHGKKFSKSFASGPWKTDFDAMAQKTILKDILSKYGPLSVEMQKAIDEDNQDST
                     ISIPKDITPPETNSLDDLIGHQNEKKDAPGNLKDVTDDLHSEPEKTLTDENKTVLEDT
                     SYPADEIPDFDQETGEIKASEGNLFDNLGDLI"
     gene            8307..8507
                     /locus_tag="TVB59_001073"
     CDS             8307..8507
                     /locus_tag="TVB59_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009974.1"
                     /translation="MIKLVKIEGYYINPEYVVGVWERSALNFDDLDEKVVVIQFVGDR
                     EREECVFYDTPIDEVIKRLLDD"
     gene            8500..9297
                     /locus_tag="TVB59_001074"
     CDS             8500..9297
                     /locus_tag="TVB59_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease-like domain-containing
                     protein"
                     /protein_id="HEL1009975.1"
                     /translation="MTSLDLLGKDYYSKESAIRYWSISQYKRFRECEARALAELRGDW
                     TDTRDNTALLVGNYVHSYFEGEEAHEEFKVQNSSEMISTRGTTKGQLKKDYLVAEQMI
                     DALKSDNNFMAIYQGEKEVAITGFLGEVEFKGKIDCLNAERGYFVDIKTTKGPIDDKI
                     WNGQERVYWFEAYSYILQMAAYKNMLEAKHKKPFEPIIYAVTKETPPDTRAIRIQNLD
                     AMQNELDNLAQNIKRLDDVKKGIEKSKPCGHCEYCRANQLTQRVMIF"
     gene            9476..9817
                     /locus_tag="TVB59_001075"
     CDS             9476..9817
                     /locus_tag="TVB59_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009976.1"
                     /translation="MEQIKITGTGTALILDRVNRIFAISGGLTMQWDFISDFKKIDDE
                     PSLDEDGELFEVAYDLVLEAKPKTKINLTSSYFAKEHKKDTDEIIKVFSFIEDNKRNI
                     FETLGIRGVLE"
     gene            9814..10326
                     /locus_tag="TVB59_001076"
     CDS             9814..10326
                     /locus_tag="TVB59_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009977.1"
                     /translation="MSNLVLSLDISTSGTGWALFKGSDLIQSGVLKHKSDSYFERGRY
                     MASQLRAIQSRALKKYDCSFSTIAVEKNSVMGPNQQSMLKIGIVTGIILGRLIADNVV
                     FINVSTWRKHWKFSYKDRSKKAMKAQSKAKAAENFGKIVKDDEADAVLIGAYYVNQGY
                     LDGLETHDYY"
     gene            10313..10525
                     /locus_tag="TVB59_001077"
     CDS             10313..10525
                     /locus_tag="TVB59_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009978.1"
                     /translation="MTTTKKHVVRIYNKGITATYAVTDKRLFREHEFATKREAMQFIR
                     ELELANDKRATEYYLREWRDANGRYV"
     gene            10503..10787
                     /locus_tag="TVB59_001078"
     CDS             10503..10787
                     /locus_tag="TVB59_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3310 domain-containing protein"
                     /protein_id="HEL1009979.1"
                     /translation="MLMEDTFKKIKELEAACQDRTDNIKKPSHYQGRHGMEAIDVVKN
                     FAACPEHEEGFYWGNAVKYLLRYHAKNGVEDLKKARQNLDWLIEKLEEVE"
     gene            10812..11024
                     /locus_tag="TVB59_001079"
     CDS             10812..11024
                     /locus_tag="TVB59_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000010060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009980.1"
                     /translation="MSFRLSWEINGQTVEVIGDYKTLKAAYDSIKVHVKDRDKFASPY
                     YRIWQKGAVHFVDYGKHNAFYKIEER"
     gene            11029..11229
                     /locus_tag="TVB59_001080"
     CDS             11029..11229
                     /locus_tag="TVB59_001080"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009981.1"
                     /translation="MMDTETLEAVYDALQLSLPKIIDMLKAASATRDDAYKEGVLDGA
                     DLIADTVIKAIGQMIDPEADHG"
     gene            11222..11449
                     /locus_tag="TVB59_001081"
     CDS             11222..11449
                     /locus_tag="TVB59_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009982.1"
                     /translation="MAKDDFLTGFVLTLLAACVFAAGFVIGSDCSSEHYEQQMTDLRM
                     QLVSTQQQLKQSREQNQRQTKRIAELTGNGG"
     gene            11460..12149
                     /locus_tag="TVB59_001082"
     CDS             11460..12149
                     /locus_tag="TVB59_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002814908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEL1009983.1"
                     /translation="MEIKCGNCLQLLTELTDGSIDMVITDPPYNISVKNNFATMGRTG
                     IDFGDWDKGFDLLSWIDIASRKLTKNGGMVIFNDWKNLGDIARHCEKTGLVVKDIFRW
                     VKDNPMPRNRDRRYITDSEYGIWVVRKNSKWVFNRKSEKYDRPEYRYPIVAGLEKTQH
                     PTQKPVALMRDIITRHTTKGAVVLDPFMGSGSTGVACLLTERDFIGYELNKDYFNIAK
                     KRIAELTGNGG"
     gene            12153..12335
                     /locus_tag="TVB59_001083"
     CDS             12153..12335
                     /locus_tag="TVB59_001083"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009984.1"
                     /translation="MPELINTADLQTPIEALENNLDFFKSFYNDERFEDMENAKKLIE
                     RYEKAISILTEVQNES"
     gene            12325..12483
                     /locus_tag="TVB59_001084"
     CDS             12325..12483
                     /locus_tag="TVB59_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009985.1"
                     /translation="MKVKDLHKVLAKVDPELEVWINEKDGGVITKAKNVMTWNEHPNK
                     FFINAETQ"
     gene            12502..13083
                     /locus_tag="TVB59_001085"
     CDS             12502..13083
                     /locus_tag="TVB59_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEL1009986.1"
                     /translation="MNIEEAIKYFEDKRKDYIVSPSVIHVSTVEVINILKQIKLDKPK
                     PEIPQFVADWIEGHKADYITWEKADKADFVFRCINDLFNFGADMHTYDFDVSYEISKW
                     TQEHAYGFIVAVLFGYTIKKEKLYIVEIPNPNSGIEHKHIALARLANGKLGFSEIIDT
                     DFYSREDVRLTESEIRKDFDWAWERGFAKGVKE"
     gene            13080..13247
                     /locus_tag="TVB59_001086"
     CDS             13080..13247
                     /locus_tag="TVB59_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009987.1"
                     /translation="MNKSEIKNLVDRLSDLIDKCENDFEAMVFNPDGTFDLLLASHSA
                     LSKVLRGEVTE"
     gene            13244..13459
                     /locus_tag="TVB59_001087"
     CDS             13244..13459
                     /locus_tag="TVB59_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009988.1"
                     /translation="MKSYQKRFVEEYRQLTQRLSKLDKMLKKYAQGTLGFEPDCPIRL
                     LQEQRRVMSEYVDILEARAKFEGVDLE"
     gene            13533..13970
                     /locus_tag="TVB59_001088"
     CDS             13533..13970
                     /locus_tag="TVB59_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEL1009989.1"
                     /translation="MGNIPTPKANNFLEELKTIPDLIETLERDANLMSRSLIKSPQWS
                     DMRVSGGVKQSQEDKNIKMLHMVSYYSDQIERLKDRRQEMANLIVQSMGICESHVLLT
                     TYLDCDGDYERARERLNIGNRNKYFMFVRRGKESLELILKNTN"
     gene            complement(14475..14852)
                     /locus_tag="TVB59_001089"
     CDS             complement(14475..14852)
                     /locus_tag="TVB59_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEL1009990.1"
                     /translation="MLIYPATFTQDTDYIMVTFPDVPEAITQGKDFQEAYEMAVEVLG
                     FALEDYTDYPKASSVSDLKEQYRDSDIALIGIDMIAYMKKYHSKKVRKNVTIPEWLNK
                     AAEDENLNFSQVLTEALELKLQA"
     gene            complement(14904..15089)
                     /locus_tag="TVB59_001090"
     CDS             complement(14904..15089)
                     /locus_tag="TVB59_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEL1009991.1"
                     /translation="MPMTPKQMIKLLKKNGFYEVSQNGSHKKFRDNNGHQTIVPLHNK
                     DLGKGLEDTILKQAGLK"
     gene            15205..15540
                     /locus_tag="TVB59_001091"
     CDS             15205..15540
                     /locus_tag="TVB59_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEL1009992.1"
                     /translation="MRPQKLTIAGGRRTTVDYDDRSAEYRDYNRNRWKYDRKTKQFYN
                     SKIWRETSKQVLLQSDYICAMCGGEATMTDHIVSVKKDWNKRLDWNNLQASCKACNDC
                     KAIRERRKT"
     gene            15703..16170
                     /locus_tag="TVB59_001092"
     CDS             15703..16170
                     /locus_tag="TVB59_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HEL1009993.1"
                     /translation="MGRNLKLVETTKKHLTKEEKIVRETAQNKASDGLKKLQKTPPEH
                     FNNVAKYEYRRIIEDLQNLPLRNLDRGLLELYCTWYAIYKETSRKLDEVGYFTNDPDK
                     GIIPSPLILTLEKATANIRSSASQLGLTVDSRMKMFIPKEEEKPKSIFDKFGG"
     gene            16185..17939
                     /locus_tag="TVB59_001093"
     CDS             16185..17939
                     /locus_tag="TVB59_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HEL1009994.1"
                     /translation="MTIEYDYSAIGDIYKDDAFYYAKMVVDEEIKASKKVFKACLRHL
                     NDLKKIDDDNFKFIYLPKKAIDPIIFIELLPDVKTGKPYPLAMFQKFIIGNLYGWRKK
                     TDHSLRRFRKAMISVARKNGKTILIAGILLYEFLFGHNPSMSRQLFCTANDRTQAKIA
                     WDMAKKQLSSLRAKDADVRKATKIVRDELKNLHDESYIRALSRDTGAVDGFEPYVGVL
                     DEFAASKTNEMLELLESGQGQLDNPFILIISTAGMDLNVPMHTIEYPYITKILDEEIV
                     DDGYFGYVAEQDNEGEIKDESNWIKSNPILEVEALHDKLMDYLRTRRRVSLETGEINK
                     VLIKNFNMWRQSSEESYIDKQSWELARIDKPDTHKRRVWLGVDVGRVSDLFAITPVIM
                     MDDFWYIDSFSFVATKYGLTAKEKRDGVSYSNLERQGYCEITTLESGVIDDERVLEKI
                     EEMVYSNDWEVNGICFDPYQFGTLLTMIEKRHPEWPLIEVSQTTMVLNMPTKQFRDDL
                     KNGKIKHSGNPLLTMAVNNAYIKTDNNGMRIDKNKNSNKIDPLDAALDGYAVCYLEPF
                     DGSGYWTSEKILGGETLF"
     gene            17936..18106
                     /locus_tag="TVB59_001094"
     CDS             17936..18106
                     /locus_tag="TVB59_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009995.1"
                     /translation="MIGFILKNIHTLILLAGLGLLMYGLFLFGDKVGFIASGLILIFL
                     AIYVDSVGGKHE"
     gene            18099..18365
                     /locus_tag="TVB59_001095"
     CDS             18099..18365
                     /locus_tag="TVB59_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1009996.1"
                     /translation="MNKRIKKKRKLETAVVMLVAENAMQAEVLRNQNRQIAELRSIIQ
                     QNAQATNREFAAVKSATLDNQAAIKKIGDEVYYIKQNYKRKWRK"
     gene            18399..19619
                     /locus_tag="TVB59_001096"
     CDS             18399..19619
                     /locus_tag="TVB59_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000007730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEL1009997.1"
                     /translation="MSFFQPLGSSKVSYDDYVSSVLAGDVSQKYLGVSALKNSDILTA
                     TSIIAGDIARFPLVKKDVNGDIIHDEDINYLLNVKSTKNASARTWKFAMAVNAILTGN
                     SFSRILRDPKTNQALQFQFYRPSETTVEETDNHEIVYTFTDMLTAKQVKCFAHDVIHW
                     KFFSHDTILGRSPLLSLGDEIDLQTGGINTLIKFFKDGFSSGILKMKGAYISGEARKR
                     ARVEFEKMREGAIGGSPLVFDDTQEYTPLEIDTNVLQLITSNNFSTAQIAKALRVPSY
                     KLGVNSPNQSVAQLMEDYVTNDLPFYFDAITSELGLKTLSDKDRRLYRIEFDTRSVTG
                     RNVDEIVKLVNNQILTPNQGLVELGKQKSTDPNMDRYQSSLNYVFLDKKEEYQDKVGI
                     KGKGGEVNAKEDKS"
     gene            19597..20262
                     /locus_tag="TVB59_001097"
     CDS             19597..20262
                     /locus_tag="TVB59_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HEL1009998.1"
                     /translation="MPKRINLKGPLIANNSQEVYDYYGMEAASAKSIIEQFPEDNSDI
                     VLEVNSNGGLVTVGSEIYTALRNYKGKVTAEITGMAASAASVAVMGADKVVMSPTAQM
                     MVHKALFKWVSGNSDDLDKASNALKSSDKAIVSAYVAKTGLSEDAIMDLMRNETFMSA
                     QDAVEKGFADEVMSFEAVASIDNSMLPQAVIDDYYRSRNKRKQEISNMLLEIEKEEIL
                     RGL"
     gene            20287..21474
                     /locus_tag="TVB59_001098"
     CDS             20287..21474
                     /locus_tag="TVB59_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HEL1009999.1"
                     /translation="MFEEKIKEIKANIANLNQAIATKTTEVKNALESDDLETARSIKA
                     EIEEAKANLAEAENDLKLYEASVEKGGAENTGGKEVPQETKTYRESVNEFIRSKGTVT
                     NEGLRFEGKDEVLIPLNQTTPVDPKTDGVKKTDVKPVSSEEILYTPAREVKTVVDLKQ
                     FTSIHPAKKESGKWPVLQRATEKMVSVEELEKNPKLGKPQFKNVEWEVKTYRGAIPLS
                     QESIDDADVDLVGIVAETIGQMKVNTTNDAIAKVLKTFEAKAGVKTLDDIKKILNVDL
                     DPAYNVSFIVSQSFYQTLDTLKDKNGRYLLQDSITSASGKVFLGKPVFVLSDDVIGED
                     SAFVGDFKRGVLFADRKDLGLRWADNEIYGQYLQAVLRFGVAKVDDKAGYYVTFKPEQ
                     LPS"
     gene            21619..21921
                     /locus_tag="TVB59_001099"
     CDS             21619..21921
                     /locus_tag="TVB59_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HEL1010000.1"
                     /translation="MAVSKELLDSVKLYCKIDFDFDDDIIKEMIESAQEQICFAIEDG
                     STPEKFKGHAKFNLAVKKQVKEEYDHRGLSADSFRYPLANGVLNIIHQLRLRGDDS"
     gene            21918..22265
                     /locus_tag="TVB59_001100"
     CDS             21918..22265
                     /locus_tag="TVB59_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HEL1010001.1"
                     /translation="MITRKMNVRITIFSQSGGQNEDGEVVSAVRKDLYTCWAEVLKTQ
                     LRDFNYQSKYQNASNLPTNKDTKVFLIRYNPELSIDNTMFVEFGKRIYKIDKIESDES
                     GKDIIMISGVSMS"
     gene            22262..22639
                     /locus_tag="TVB59_001101"
     CDS             22262..22639
                     /locus_tag="TVB59_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEL1010002.1"
                     /translation="MTKGLDEILANLTKLEVKAPKTAKAAVTEVAKEFEKALKANTPV
                     YEIETDERLQEDTVISGFKGANVGIVSKEIGYGKATGWRAHYPNDGTIYQRGQDFKEK
                     TINQMTPKAKQIYAAKVKEGLGL"
     gene            22636..23106
                     /locus_tag="TVB59_001102"
     CDS             22636..23106
                     /locus_tag="TVB59_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010003.1"
                     /translation="MIAETAAYKLLSNDKTLNELLDRLRGGPFKNGFKQGIFTYDIPD
                     NPVDLRKVDLAPFMRINTTLDGPADYADDEILCNEQRITINFWCKTASEADQISKCID
                     DILKKGGFERYTANEKPRYKDSDIDLLMNVRKYRYFDFYLKERGKNGKSKIWTT"
     gene            23078..23668
                     /locus_tag="TVB59_001103"
     CDS             23078..23668
                     /locus_tag="TVB59_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1010004.1"
                     /translation="MGKVKFGLRDFQYAVLGEDDNVATKKGGIKKLPGMKSAKLDITN
                     ELVTVSADDGPYVVLSGGITETKLEIEVLDLTTDARKDFFGIKVAAGVEKYNKNLTPN
                     NVACIFRTSDENGKAIWVGLLKGKFNLPGMETQTKEGSPNPKADTVTGNFVSRGTDGD
                     VLVIGREESHEFNYEAFAGFVFAGATDIKKGENFEM"
     gene            23720..24046
                     /locus_tag="TVB59_001104"
     CDS             23720..24046
                     /locus_tag="TVB59_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010005.1"
                     /translation="MYEITLKKGGVDKVFSKDFINVEDNLLAVEHQVRQSAVFSDEKR
                     RLDSKAHRKLNESYLQMFVDMYAGQFTVDDLKQSDMSVLNTLNDLYIAALGGEQEEDE
                     SEKKEQ"
     gene            24094..24243
                     /locus_tag="TVB59_001105"
     CDS             24094..24243
                     /locus_tag="TVB59_001105"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010006.1"
                     /translation="MKNGYTILDIKKMRLSDIELMVQALEIETVEKEEVIETTLDKAF
                     PFLFG"
     gene            24256..28179
                     /locus_tag="TVB59_001106"
     CDS             24256..28179
                     /locus_tag="TVB59_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HEL1010007.1"
                     /translation="MGNIGDLVATATLDISPFMSNTRNLKTYMKGLDNSLKAVEKSFQ
                     GHGGRIKGLKAVYAETGSALKGYQELLKTQSQKYSDLKKEIGDVNNATAEQKQKLIGA
                     KSAMLETAAKVTELQNRLRALATETSVFTRFGKAAEKIGGKMKSLGDSVAGVGAAFTR
                     GVTAPIVAGAGYAIKAAVDYETAFAGVKKTVDETATVSYAKLSQGIRQMAKELPASAV
                     EIAHVAEAAGQLGIKTGDILSFSRTMIDLGESTNLSAEEAASSIAKIANITGLTSKEY
                     SRFGSSVVALGNNFATTERDIVAMTNRIAASGKLAGLTNQEMLALATAMSSVGIEAEA
                     GGTAMTQTLSAIETAVINGGEDLTKFAQIANMSSADFARAWKEKPIVALQEFIKGLGQ
                     LDKKGESATKVLDELGLSGIRQSNMLKSLGLASETLGKALGISNKAWQENTALTDEAN
                     KRYETTESKLKMLKNEVNDVAIEFGGPLVDALRNGLEAGKPIIQMAADLAKQFNSLDK
                     EQQQQIIKWGLIAAAAGPALSIFGKGVGIIGSTIQGIGKMSQGLGALSGWLRTFKTGA
                     AAASAGAEAATASMGGMAGAVALLSNPVTWGVLLGGAAIVGIGLIADSMYKAQKRTEE
                     WGTAVSATEANALSNFKKKVDETNTSLQMFEAGAGSVKKVTEAFDDLVGSIEKLAQSK
                     LDKNINLAKKLGLSEETINALKSKTESVVNNVKSMNTQIKAIMEKHNGDMSQLSSAEK
                     ELVLRNQREMITAQLDLMKFSASEKKALTAALNNELDALNARQLEKVSENTVKMLDKE
                     NSAYKTKKAELKEILKQFGSDTSKLSAEELAARQEVLNRLTELNMQHNLKTKALNDQY
                     LAIQRERVQRLKESGKSQEEIHQGISQMASDMAQKLGISYDDAYRKLAYYTEKSGETL
                     KVLSRNTANATAEVAAANAQWDSLFTSDNPQQSLNELLSTAEGWNSFEIMVKNADVEP
                     TGRAALAEMLVAGGQWENMTLEQKKLVVDGQQAMIEIFDSKELLAQWQALTPEEKVLL
                     AKNLTQEPTMSAQQALDSVKQTVPADVNASDKTAGETQSAQNKIDNVKQRVPADVKAS
                     DKTGPDVASADRAVNSPKQKSPAVIRAQDNASGVAEGVIGALARIPRSVTTTITTFVR
                     KIFGHEKGTDFHPGGLAMVNDQKGPLYKELVTLPTGESFIPSGRNVILPLPRGSKVLK
                     ASRTKQLFPHYASGIGFDDTKIASLTTRLKSVQDKGQVIINTDPQLAELIKLLKDRDD
                     RNVTNNYTVNATNSSSSEDMFSQENMRRLLRELAYYTNGEGGRLA"
     gene            28179..28886
                     /locus_tag="TVB59_001107"
     CDS             28179..28886
                     /locus_tag="TVB59_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HEL1010008.1"
                     /translation="MRYIEFNGTKSNDLGLLLERERSIKSTNNDIDLIEVAGRDGVLI
                     KDNERLKAVEQDFPFSLVGDVTVNQQKISEWLHVKGWHDLALSWDKDYIYRASVVNLF
                     EIDEILKQFGRLKVNFLIHPIKYLKTGKQEVPLVNGGTLQNPGNVQAKPILKIKGTGN
                     GVLTINDFETGLENVQGELVIDMERHLVYKDVLSAWDNIVRTEHHRMPLFDIGQNKIS
                     WTGNFTITAVPNWGVKV"
     gene            28883..>30363
                     /locus_tag="TVB59_001108"
     CDS             28883..>30363
                     /locus_tag="TVB59_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1010009.1"
                     /translation="MIPVLYEAKETKFRTFGLGEIADAYEVKATRERNGNYSLYIKYP
                     LDGAFAHLFKEEMKIKSDAGRRTKWQTFEINRVLRNSKEHIEIFARHISMRTQDIALK
                     PFVSGSSIDAESALEVWRDNLVGDDTFDVKSDILTLGSFNWEVDKIGNARGALGGVAG
                     SILDVYGGEYEFDNRTIILHKQMGRKTPTVLEYGRNIVSVEEERLLDGNYTSIYPYVR
                     YTPQPKPQEEASGKPHIGEHEKPEEQLVTLPEFIIDGQYLDLYAQRRIQMVDLSSHFN
                     DDKKEPTVEEIRKLAQKYLKDNNVGAPKISIEVDYIDLSQTLDYQDFRVMEEVELCDI
                     VPLYYPKFGITTETEKVVEIVYDVYTDSNHTIKLGTIGQSISKSLTGGVTQRIETLEN
                     NQKVITNNQQQFELNLPKYLNDLNGTKIWYEKPDDNVEHKIGDFWFEKNGKYQRTWVW
                     DGNQWVKIIDTEDLNPNQRAFDEAMAEIEKLKQHQQQIDKRNQR"
BASE COUNT        10551 a         5037 c         6609 g         8166 t
ORIGIN      
        1 tggaaggagg aacgatatga acgaactaga aagaacagcc cttaatgaaa tcatgaggac
       61 agtgacttat atagcggaga agctggataa aattgattct aagatttctc agtctgtaga
      121 agtgaacgat agtgcatcgt cagcgtcgta gtctgccgca acaaattgag cagctgctaa
      181 aataaaacgt ttgagatcct gcaagtcttt attattatgt ctacgaacat aatgagtttc
      241 atcgttacca atccacgcca ccgagcgaga tagagcttgg agtttaggga agtcggagag
      301 atagtcacta attacttttc caagcataat ttgtttgatg ttgtcgctgt cgtcaggatt
      361 ctttgatatt gtataatctt tgattaaaaa ctcagcagct ttacggtaac caacacctgc
      421 aatttgatcg agtttttctt gctctgcaat tgtagcttgg gagtatatct ctacaaatgc
      481 tggcgacact ttatcaacgt tttcaggaag attcactcta ataggtggac gatagaagta
      541 ggcgacagct gatcctttac caatctgatc gtggatatac tctacagcaa aatattttaa
      601 gcaatcatcg aaagagcaac ggaatatcac tgaaaaatgc ccctgatatg aataactttc
      661 attgtcagaa cttttgcttt cgccaacgtg ttgaggggac atagttcgac cacagtgggg
      721 gcaagtcgaa ggtgtatcaa tcgtgattgt acttctacga tctctaaatt gtataactac
      781 atcaagcaac attattattt ctctccaatc gttttattta aattatacca cagaaagggg
      841 gtggggaaga tggaagaaac agcctcagta aacgtaactg taaaaattaa taacataact
      901 gagttttcaa ctttagttga aaagttcaac gaaaaagccc gtgagttaga agcgatttct
      961 cacgagctaa tgcgtttcaa atttcaaggc gagattgaaa gtcgtgcgct atcagataat
     1021 gctaacgaaa ttgaataatt tatctttatc aattttaacg cacggtaagt aactataatt
     1081 ttcgacatat cgaaaattat aggcaaaatt agtatttttg atttcttttt caaattttgc
     1141 aaaatccgct tgggatagaa gtttgaaaat ataagctctt actcttgtta tgtcggtaag
     1201 cattgagagt gtaccaattt gccctgattt taagtttaag atgctcaaga tctcagtaac
     1261 atcaatactt ctgtggtttt ctagctcttc atatgagccg agttcatact cataaaagca
     1321 gcaatgccca acttcttgat atgtattgaa agtcacaaag tctccgttga attcaaaaac
     1381 tagtttgtca ttaagcatat tttctttgat gtcaatatgt actctatcaa caagatatct
     1441 atgacaagct tccaataatc gaacttgatt taaatccatc acattcacct cctttctgcc
     1501 catattatag cagattagag gtactaaaaa cagatagaaa ggaggtgggg gaatgcagat
     1561 tcttctgtat aaactgcgaa aagaaaaaag aatttcacaa gaagagatgt ctaaggttat
     1621 taataagtct tctaacactt accgagataa agaattaggt aaaagagact tcacacagag
     1681 tgaaatgttt aaaatcgcca atttctttca caaagaatta ggcgaaattt ttacaccata
     1741 aacttcacga aacgtgaaat ataaatcaac acaacactag aaaggaacaa catgaatcaa
     1801 ctaataaaca tcaccctaaa cgaaaatcaa gaaccagttg tcagtggtcg tgatttacat
     1861 aaagtacttg aaatcaaaac agcttataaa gattggtttc caagaatggc tgaatatggt
     1921 tttgaagaag gtcaggactt tagctcattt ttgagcaaaa gtacaggagg tcgtcctagt
     1981 caagaccacg ttctaaaact agacatggca aaagagattg ctatgttaca gcggaatgaa
     2041 aaatctaagc aagtccgcaa gtattttatt caaatcgaaa aagactttaa cagccccgag
     2101 aaaattatgg caagggcgtt gctgatggcg gacaagaaag tgcataaatt agaagctcag
     2161 attgaggctg accgacccaa agtactattt gctgatgccg taagtgctag caaatcatct
     2221 tgtctgattg gtgagttagc taaaatcctg aaacagaatg gaatcaatat tggtcagaat
     2281 aagctatttc agtggcttag aacgaacggt tatctaatta gcagacgcgg cgagtcatgg
     2341 aatcagccaa cgcaaaaaag tatgcagctt ggattgtttg aactcaaaaa aacagccatc
     2401 aatcactctg acggtcacac tacaacaaat gtaaccccaa aagttactgg taaggggcag
     2461 cagtatttta tcaacaaatt tcttaaccag gaatatctgc cagtttagaa aggaaaccac
     2521 atgagaccaa aacgatatcc gtatacacca aaaagaccct ttccgagtca agaaagagtc
     2581 gcaagttata gattggctat tgaagagtta aattctttag caccaacagc atccgaaaca
     2641 ctaaagaaaa aaatagaaga agctaaaaaa tatcatttga gttttctgaa gccttttgat
     2701 cttgattttc ttctaaacga gcaagaatct cagcttcatg ttgaataaga attttttgaa
     2761 tatgttcctg gacttcacga actctaactg gttcgaactt acttctatca cgaaccaatt
     2821 caataatttc gtcgatttct ctttgaatat aacgaccagg aatatattta tcaaccatgt
     2881 aatttatcct cctttatagc atatttgact aacgacttca taaggaatag atggtttgtc
     2941 ataaatcaat tatagcagaa agagggggca tagaagaatt tatatacaac aaaaaagtcc
     3001 gacgggaatc ggactcaaaa caaaaactat ttacttagat tataacacaa gagagaggaa
     3061 ggttccatgg caattgaggt atttggacca gatttcagaa aggaactact tgcagacttg
     3121 atttctctaa acagagaagc gctaaaaatt gctcaattcg agaactctaa gtcaattgag
     3181 tgggttacca tgaagcggtt ggaaaaagaa actggatggg ggcgaactaa attgacccag
     3241 tggagagaac aagggaaatt taactttaaa aggtcatcag aaaacgggaa agtactatat
     3301 gacctagcag atgttaatag atttttgcga acaagtggat atgaaaaagg agcataacat
     3361 gaacaaacta gaattatttt tattagcagc aaccgtcatc ttagcaatca ttgcaagaat
     3421 tcagtatgaa gtcataaaaa aacataattc gcccgaaaat aagcgaaaaa tttttaggga
     3481 agtagcttta gaaaacagca aaagatggag cgagaagcgc tctagaggag aggtagaaaa
     3541 atgccttttg taaaacggta gaaaccacat agtcctttga caactgaata gggtaccttg
     3601 aaaaaatatt aaaaaagttt gattttgggg ttgacttatg tatccacata atgatattat
     3661 atatttgtgg atacgaaagg aggaaatatg accactacca aaaaacttgg tcgtccaact
     3721 tctaatccta agtctcatag caaaagactg agaatgacag acgaagaagt acaaaaatta
     3781 gaatattgta ctaaacaaac tggaaaaact cagacagatg ttttgatgct aggcttagat
     3841 aaggtctatc aagagctaaa aaaatagcgt ataatccgcc atcgccaaac tttggattac
     3901 acgctatcga ccgacctgaa aacaggtaca caaatatatt atcatgtgta cccttttcag
     3961 tcaacctgac aagggtattt tttgcgccct tgttgtttag ataagggttt ttattgtacc
     4021 caaaaatagg aggaacacaa tggataattc aaaactagca aatcatcaaa aagtaacggt
     4081 agtctgtaca gattttaatg tctatttgaa tggaatacga cttactggag ctagaccaga
     4141 aaccgctaaa ttagctgaga gatgcggaga gaaactcatt acactaagtc tagtagttac
     4201 agattttgat gaccatagaa cacctaagat ggcggatatg gcaaaggagg ctgagatggc
     4261 taataaaaca ttggactggg agaaaaagca tttctataaa tctaataaat aatgtatctc
     4321 agagcgttat agattgattc tggattttgc gaaactccaa attcattaag ccattcgata
     4381 acctcggttt ctacctgccc gatatatcca agaaaataca tgccttttgg tgtcagaccg
     4441 tcaattgtat atattcgtct atctaatctc ggcatttctg tggcagtaac taaatcttgt
     4501 tggatcaaac aatctagggt gtaaaaaata atttcttcaa cttctcgata agggtattga
     4561 gaatatatcc tttttccttc ttctgttgca ataaggtatt gaagtaaatc tacacccgta
     4621 tccaacttat gatatccgat ggcttcaagt gaatttttgt ataaagaata gtaatcaatc
     4681 atacacttct ccaagtattt tattttaaat ataacaaaat agtaagagga aaacaatatg
     4741 gctaaaactt acacattaac cgaagaagaa ttgaatgaat tagtagctga gcgcatgaaa
     4801 caagcgaaag aaaaacgcac accacaagga ctattcaaag atgtcagctt tgatgatgag
     4861 ttgattccaa tcaatgaaaa atatccaaaa gtactcaaga aattaaatcg tgaacgtgct
     4921 tataaaccag aaaaacacgt cttcaatcag acaccaaaag tttttggtgt ggacaacgat
     4981 attagttata gcaaaattac aacacatgac gtacacaacc atattcgttt gcttgtccta
     5041 aatgtctttg gtaaaagtca aaataaggaa gtattgcccg aggaatatga ccaagcaata
     5101 gagctttaca aggaattgaa agaatggttt gtgtctagct atgataagcg attagaggga
     5161 ttggtgctag aagatgatta aaaaattctg cgttaactac ttactaagac agattaacaa
     5221 aagcaaacta gaaacaagag ataaagcgaa gttaaaccac tttatcacac tagtggacta
     5281 caagttagga ggataaattg ggtaaagaaa aaactaaaat atacttttgg ctaaagttcg
     5341 acaagaagtt ttttgaaaat atttttatca aacgtttaaa aaagatggct ggcggagaca
     5401 ctatgacagt cttgtatatt cgtttgatgc tagaaagttt agaaacagac tgcattttat
     5461 attacgaagg atactttgaa aatttggtag aagagcttgc catcaagtta gaggtgtctg
     5521 aagacgatat caatatgaca ttagcttact tcacaaaatg tggtctaatc cagatagacg
     5581 gtagcggtaa cgcacaaatg ccccaagcta aagctatgct ggaaagtgag acgaactggg
     5641 caaaatataa acgagaaact agaaaaattg gacaaattcc aaccaatgtc caaccaatgt
     5701 ccaaccaatg tccaacagag atagagatag agaaagataa aaagaaagat ataaatatag
     5761 atataaagtc agaagtagaa gaagagataa aagagatttc tactgctgac gaaaacagtc
     5821 tcaaaattat atctgattat ttccaacaag aaatcggtat tttgtctcca aatcagtttg
     5881 agcagctgtc agactatatt accattacaa aaatggaggt agatgttgtt aagtctgcta
     5941 ttacaagagc tgctgacaat tctaaacgtt cttttggtta tgttaactct atactgcgca
     6001 attggcgaca aaatggaatc accacaatgg taaaagtgaa agaagaaagt aggaatttta
     6061 aagccagaaa agctaagcaa gaagaggtct cagaatatga cacttggtga caacaacgca
     6121 cttgctaaaa tcgctgtagc ttatcaaaaa aatgtcaaaa aagaaagcac tgtttgtcaa
     6181 aaacatggtt gcatctatat cacaatcctt aaaactggat tgacagtatg tccgatgtgt
     6241 cacaaagagg acttagaaag ccaaaatgag ttacacgtcc aaaagcaata tgagagagag
     6301 cttgaaaaca agcgactgta ctatctcaaa aaattatcaa ttatggacga cgagttggaa
     6361 aatgcctcat ttgataattt cagggtgatc acacctaagc agcaagaggt cctttcgtgg
     6421 gcaaaatcca tggctaatta ctggtataca ggaggcaaag gcaatatcat catgactggt
     6481 aaagctggcc gcgggaaaag ccatctagca tacagcatca tcagaggttt gtctgacgag
     6541 actaaaaagt tagggctgct tgtaaacatt actgacttgc tatcagagat aaagcgagac
     6601 tttagccaag aggcattttg gctagataag ctaaaaaatg ttgattattt ggttttagat
     6661 gacttaggcg ccgaaaaggt cagcgactgg tccacaagta ttatttacag cttactaaat
     6721 aagcgtacaa atacaatcat tactacaaac ttaacacctg ttgaaataag gaaaaattat
     6781 ggagaacgta tcgcatcaag aattagaaaa ggctgcgcta agagccatat tatggatttt
     6841 gcaggactgg aagatgagag gatcaagcta tggaactaat attaataact ttttttggcc
     6901 tatctgaaga acatgcagcc aaaatcatgg cgctagacga agatagccga ataaataaaa
     6961 tcgaggaatt gagagcatgg agagaatgct caaaaataac attttaggag gaaatatgac
     7021 accagaagaa gcagaaaaag caaaaatcag agctaaacaa gaaattgaag tttttagcat
     7081 ataccttgaa caggcgattg atacttttgg cagcatgcta agcccacaag aagtcttctt
     7141 ggcagcaggg tttgcctacc ttggcgctgg tcaaacagac atacatgcgg ccgtcgaggg
     7201 gttgtatgag caagttcgat gactttaaat ttagcgaaga ctgggagagt aactactttg
     7261 aggtccaagc tttgctagga caagagatag acaagctaca aaatagagtt gtccagttag
     7321 caaacgaaaa taatagatta aaggccgaaa attggcagtt aagacacaga aagaggaaat
     7381 gaaatggcga atcaattatc aacatacaca cacaaacaat tttttaatgc accaacaatt
     7441 caaaaggctt ttgatgacgt ttggaaaggc gccgggacac agttcgcagt aagcatcttg
     7501 tcagtactac aaggtagtaa aagtttgaaa tcggcatcta atgaatctat ttatgcagca
     7561 gctatgaaag cagccgtgtt aaatctgcct attgagccaa gcttaggaag ggcctattta
     7621 gttccgtaca aaggtcaagc acaattccaa ttaggctata aagggttgat tgagttagcg
     7681 cagcgcagcg gacaatacaa aaatattaat gcaggtatcg tctataaatc acaattaatt
     7741 tcttacaacc ctttgtttga ggaattgatc cttgacttta gtaagccaca agatgaaatt
     7801 gtagggtatt ttgccgcttt taaactttta aatggattcg agaaagtttc tttttggaca
     7861 gtagaaaaag taactgcaca tggaaagaaa ttttcaaaat cgtttgctag cggcccttgg
     7921 aaaacagact ttgatgcaat ggctcaaaaa actattttaa aagatatttt gagtaaatat
     7981 ggtccgttat cagttgagat gcagaaagct atcgatgaag acaatcaaga ttcaacaatt
     8041 tctattccga aagacattac accaccagaa acaaacagcc ttgacgacct aattggtcac
     8101 cagaacgaaa aaaaggacgc tcctggcaat ttaaaagacg taactgatga tttacattcc
     8161 gagccagaaa aaacgctcac agacgaaaat aagacggttt tagaagacac ctcttatcca
     8221 gctgatgaaa tccctgattt tgaccaagaa acaggcgaaa ttaaagctag cgaaggcaac
     8281 ctctttgata atcttggaga cttaatatga ttaaacttgt aaaaattgaa ggatattata
     8341 ttaatccaga atatgttgtt ggcgtttggg aaagatctgc tttaaatttt gacgatttag
     8401 atgaaaaagt agtggttatt caattcgttg gagataggga aagggaagag tgtgtctttt
     8461 acgatacacc tattgatgaa gtaattaaga ggttgctaga tgactagttt agacttactt
     8521 ggaaaggact attatagcaa ggaatcagct ataagatact ggtccattag tcagtacaag
     8581 cgctttagag aatgcgaggc aagggcactt gctgaattac gaggggattg gacagatacc
     8641 agagataaca ctgcgttgct cgtcgggaat tacgtccact cttactttga gggtgaggag
     8701 gctcacgaag aatttaaagt ccaaaacagt tctgaaatga tttcgaccag aggaacgaca
     8761 aaaggccaat taaaaaagga ttacttagtc gctgagcaga tgattgacgc tcttaaaagc
     8821 gataacaact tcatggcaat ctaccaagga gaaaaggaag ttgccatcac aggatttctt
     8881 ggtgaggttg agtttaaagg taagattgac tgtctgaatg ctgaacgtgg ctattttgta
     8941 gacattaaaa caacaaaagg acctattgat gacaaaattt ggaatggtca agagcgagtt
     9001 tactggtttg aggcttacag ctatattttg cagatggctg cctacaaaaa catgctagag
     9061 gcaaaacaca aaaagccgtt tgagcctatc atttacgcag taacaaagga aacaccgcca
     9121 gataccagag caatcaggat tcaaaattta gatgctatgc aaaatgagtt agacaaccta
     9181 gctcaaaaca tcaagcgttt agatgatgtt aaaaaaggca tagaaaaatc taagccttgt
     9241 ggtcattgcg agtattgcag ggcaaatcaa ttaacacaaa gggtaatgat tttttaacta
     9301 actattgcaa agtgaagctc ggcctttgca ataatcatat tttccgagcg agaaaggaaa
     9361 attgcaatat cgtcaagtta acagtattga tgatataaag agttgctaca ctcgtccttg
     9421 ccaatgctca cacacaattt tagggcgagt gtggatttta aaaaaggtga aaaatatgga
     9481 acaaattaaa attacaggaa caggaacagc actaatttta gatagagtaa accgaatctt
     9541 tgccatctct ggcggtttga ctatgcaatg ggattttatt agtgatttta aaaagattga
     9601 cgacgaaccg tcacttgatg aagatggaga actattcgaa gtagcttacg accttgtgct
     9661 tgaagctaaa cccaaaacta aaatcaatct aacatcatca tattttgcta aagagcataa
     9721 gaaagacaca gacgaaatta taaaagtatt ctcgtttatc gaagataata agagaaatat
     9781 ctttgaaacc cttggcattc gtggggtgct tgaatgagca atctagtatt atcgctagac
     9841 atctcaactt ctggtacagg ttgggcctta tttaaaggct cagaccttat ccagagtggt
     9901 gtcttaaaac ataagagcga ctcttatttc gaacgtggac gatatatggc tagccaatta
     9961 agagctatcc agtcacgagc actaaaaaaa tacgattgct cctttagcac aatcgcagtc
    10021 gaaaaaaact cggttatggg tccaaatcaa caatccatgc ttaaaatcgg cattgtaact
    10081 ggtatcatct taggacgatt gatagctgat aatgtcgtat ttatcaatgt ctcaacttgg
    10141 cgaaagcact ggaagtttag ctacaaagac cgctcaaaaa aagcaatgaa agcacagtca
    10201 aaggctaagg ctgctgaaaa ctttggcaaa atagtcaaag atgatgaggc agatgccgtc
    10261 ttgattggtg catactatgt caatcaaggc tatcttgatg gattggagac acatgactac
    10321 tactaaaaaa cacgttgtga ggatttacaa caaaggtatt acagcgactt acgcggttac
    10381 tgataaaaga ttgtttaggg agcatgagtt cgcaacaaaa agagaagcga tgcagtttat
    10441 tagagagcta gagttagcta atgataagcg agcgacagaa tattatttga gagagtggag
    10501 agatgctaat ggaagatacg tttaaaaaaa ttaaggagct tgaagctgct tgtcaggata
    10561 ggacagataa cattaaaaag ccatcacact atcaagggcg gcatggcatg gaagcaatcg
    10621 acgtggttaa aaacttcgca gcttgcccag agcacgagga gggtttttat tggggcaatg
    10681 ctgttaagta ccttttgcgg tatcacgcta aaaatggtgt tgaagacctt aaaaaagcac
    10741 gtcagaacct tgattggtta atcgagaagt tggaggaagt ggaatgatac caaaatttag
    10801 agtgtggaag aatgagtttt agattatctt gggaaattaa cggccaaacc gttgaggtta
    10861 taggtgacta taaaacacta aaagcagcct atgactcaat taaggtccac gtcaaagaca
    10921 gagataaatt tgccagccca tattatcgca tatggcaaaa aggagctgta cactttgtgg
    10981 attatggaaa acacaatgct ttttataaga ttgaggagag gtgattaaat gatggataca
    11041 gaaacactag aagcagtata tgatgctttg cagctatcct tgccaaaaat aatcgatatg
    11101 cttaaagcag catccgcgac cagagatgat gcttacaaag agggtgtact cgatggcgcg
    11161 gatttgatag ctgatactgt aataaaagct atcggacaaa tgatcgatcc ggaggctgat
    11221 catggctaaa gacgactttt taacaggttt tgtacttaca cttttagctg cttgcgtttt
    11281 tgcagcagga tttgtgattg gatctgactg tagtagcgag cactacgagc aacaaatgac
    11341 agacttgcgt atgcagcttg ttagcacgca gcagcagctt aagcaatctc gtgagcaaaa
    11401 ccagagacag actaaacgga ttgcggaatt gacaggaaat gggggataaa aaacactaca
    11461 tggaaataaa atgtggaaat tgcttacaat tactaacaga gttaactgat ggatcaatcg
    11521 atatggtgat aacagaccca ccatacaaca tatcagtaaa aaataacttt gctacaatgg
    11581 ggcggacagg tatagatttt ggtgattggg ataaaggctt cgacttgtta agttggattg
    11641 atattgcaag tcgaaaatta actaaaaatg gtggaatggt gatcttcaac gattggaaaa
    11701 atttaggaga tattgcaaga cattgcgaaa agacagggtt agtagtaaaa gatatttttc
    11761 gttgggtcaa agataaccct atgcccagaa acagagatag aaggtatatt acagacagcg
    11821 agtacgggat atgggtcgtc cgaaaaaatt ccaagtgggt atttaatcgg aaatcggaaa
    11881 aatatgatag gccggaatac agatatccaa ttgtagccgg actggaaaaa acacagcacc
    11941 ctactcaaaa gccagtagcc ctgatgaggg acatcattac gcgacacaca acaaaagggg
    12001 ctgttgtttt agaccctttt atgggtagcg ggtcaactgg agtagcttgt ctactgacgg
    12061 agagagactt tattggatat gagctaaata aagattactt taatatcgca aaaaaaagga
    12121 tagcagaatt aactgggaat gggggatgaa atatgccaga attgattaac acagccgact
    12181 tacagacacc gatagaagca ctagaaaata acctagattt ttttaaaagt ttttacaacg
    12241 acgaacgctt tgaagatatg gaaaatgcaa aaaaattgat tgagagatac gaaaaagcta
    12301 tatcaatttt aaccgaggta caaaatgaaa gttaaagatt tacataaagt gttagctaaa
    12361 gttgaccctg aacttgaagt ttggataaat gaaaaagatg gaggggttat aactaaagct
    12421 aaaaacgtga tgacttggaa tgagcatcca aataagtttt ttataaatgc agaaacacaa
    12481 taatgttaac cgaggtacaa aatgaacatc gaagaagcga taaagtattt tgaagataag
    12541 agaaaagatt atattgtatc accaagtgta atacatgtat cgactgttga ggtcataaat
    12601 attttaaaac aaattaagtt agataaacca aagccagaaa ttccgcagtt tgtcgctgat
    12661 tggatagagg gacacaaagc agattatatt acgtgggaaa aagctgataa agcagatttt
    12721 gtttttaggt gtattaatga cctctttaat ttcggtgcag atatgcatac ctatgacttt
    12781 gatgtgtctt atgagatatc aaaatggacg caagaacatg cctacggttt tattgttgct
    12841 gttttgttcg gctacacaat aaaaaaagaa aagctgtata ttgttgagat ccctaatcct
    12901 aatagtggca tagaacacaa acatattgca ctagcaaggt tagcgaatgg aaaacttgga
    12961 ttttcagaga tcatagatac tgatttttat tcaagagaag atgtccgact caccgagtca
    13021 gaaatccgca aagattttga ttgggcttgg gaacgaggtt ttgcgaaagg tgtgaaggaa
    13081 tgaataaaag cgaaatcaaa aatttagtag atagactaag tgatttaatt gataaatgcg
    13141 agaacgactt tgaggcaatg gtatttaacc cagacggaac gtttgactta ttactcgcaa
    13201 gccattctgc gttgtcaaaa gtgttaagag gagaggtaac agaatgaaat catatcaaaa
    13261 aagatttgtt gaagagtaca gacaacttac acaacgtttg tcaaagctag ataaaatgct
    13321 taaaaaatat gctcaaggca ctcttggttt tgaaccagat tgccctatca ggctattaca
    13381 ggagcagaga cgtgtgatgt cggagtatgt cgacatattg gaagcaagag caaaatttga
    13441 aggggttgat ttggagtaat aaaaaaagac gtccatgcga acgccttcat gattaaatac
    13501 ccaacaatat tatatcatga atggagagtt agatgggcaa cattccgaca ccaaaagcta
    13561 ataatttttt ggaagaatta aagactatcc ccgatcttat agagaccctt gaaagagacg
    13621 ctaacctaat gagtcggtcg ctcattaagt ctcctcaatg gtctgatatg cgagtgtctg
    13681 gtggggtcaa acaatcacag gaagacaaaa acataaaaat gttacacatg gtcagttatt
    13741 acagtgatca gattgagcgg ctaaaagacc gtcggcaaga aatggctaat ttgattgtgc
    13801 aaagcatggg aatttgtgag agccatgttt tgctaacgac ttatcttgac tgtgatggag
    13861 actacgagag agccagagaa cgcttaaaca taggtaatcg gaataaatac tttatgtttg
    13921 ttaggcgagg aaaggaaagt ctagaattga tactaaaaaa tactaattag atacaaattg
    13981 atactacata atactaataa ccatgttatt atagtactgt tgaaataaca agaagagata
    14041 accattttac caattgacta tttatttagt cgctgacttt aactacgatc aaacttgtta
    14101 ttttactaaa gcttagtagc tttgcgttaa aggtgttaaa ttactcggtt gaaccggtcg
    14161 ggtaagtcgc aaatatgaag agagttgttg agacgtaagg aaatgtcatg tgcacgcatc
    14221 ttatgatatt gcaggttcga accctgccgt ctcaatcagc gtcggggaga cgcgacccca
    14281 taccccttta aaggcagaca cgttctgatg tgtgggtttt tatgattaac cgcaagtcca
    14341 aaaccaaggg tcgcaacctt gcttgtggtt agtagggaca acggttgtaa gtcggttcga
    14401 ttccgactgt tcctgtgcta gtcatcacat cgtgatggct ttttattatg caaaaaagaa
    14461 ccactaagtg gctcttatgc ttgtagtttt aattcaagtg cctctgtgag gacttgcgag
    14521 aaattgagat tttcatcttc ggctgctttg tttaaccact cagggatagt cacgttctta
    14581 cgtacttttt tagagtggta ttttttcatg taggcaatca tatcgatgcc gattaaagca
    14641 atatcagaat cacgatactg ttcttttaag tcggaaacgg agctagcctt tggatagtca
    14701 gtatagtctt caagagcaaa gcctaagact tcgacagcca tttcgtaagc ttcttgaaag
    14761 tctttacctt gagtaattgc ttcaggtaca tctggaaatg taaccatgat atagtctgtg
    14821 tcttgtgtga atgtagctgg atagattaac ataatgattc tccttcgatc actgtgagat
    14881 aagcaaacca tctggcaagc ggattatttt aaacccgcct gctttagaat ggtatcttca
    14941 aggccttttc cgaggtcttt gttgtgtaga ggaacaatgg tttgatgtcc gttattatct
    15001 cggaattttt tgtgacttcc gttttgactg acttcataga acccattctt ttttagcagt
    15061 tttatcatct gctttggggt cattggcata ttgcttacct cactttctat acttatatta
    15121 tacacgcaat aaacatggtt gtcaataggt atgcgcaaaa aatgcgtatt tttgttttct
    15181 attttttatt atggaggtta gggtatgagg ccgcagaagt taacaattgc gggtggcaga
    15241 cgaacgactg ttgactacga tgataggtca gctgagtatc gtgactataa tcgtaacaga
    15301 tggaagtatg ataggaagac taagcagttt tataactcta agatttggag agagacaagt
    15361 aagcaagtct tattgcaaag tgattatatc tgtgcaatgt gtggtggaga agcaacgatg
    15421 actgatcaca ttgtctcagt taagaaagat tggaataaaa gattagattg gaataacttg
    15481 caagcaagtt gtaaagcttg taacgattgt aaagcaataa gagagagacg gaaaacctaa
    15541 acgtacataa aaagtaacat acgcaatcat tgttcgggaa ataccccgcc tattttttaa
    15601 cggggctata ttgttcggaa acttaagaac gcgccctttt ctgtgcaaaa aaatcccttt
    15661 ttgaaatttt tgaaactgta aagtttgtgt aaaggaggtc ttatgggaag aaatttaaag
    15721 ctagttgaaa cgacaaaaaa gcatcttacg aaagaagaaa aaatagtgcg agaaaccgcg
    15781 caaaataagg cgtctgacgg tcttaaaaag ttgcaaaaga cacctcctga acactttaat
    15841 aatgtagcta agtacgagta taggagaatc atagaagacc tccaaaacct acccctaaga
    15901 aatctcgata gagggctatt agagttatat tgcacatggt atgctatcta caaagaaaca
    15961 agtagaaaac tagatgaggt tggttatttt acgaatgatc cagacaaagg cattattcct
    16021 agtccgctta ttttaacatt ggaaaaagcc actgcgaata ttagaagtag tgccagtcaa
    16081 ttaggactaa cggtagatag tcgcatgaag atgtttattc cgaaggaaga agaaaaacct
    16141 aagagtatat ttgataaatt tggaggatag agagaaaggg ggtcatgaca atagaatacg
    16201 attattcagc aatcggcgac atctataaag atgacgcttt ttattatgca aaaatggtcg
    16261 ttgatgaaga gattaaagca agtaagaagg tctttaaagc ttgtctaaga catttgaatg
    16321 accttaaaaa aatagatgat gataatttta aatttatcta tttaccaaaa aaagcaattg
    16381 accccataat ttttattgag ctattgccag acgttaagac gggaaagcct tatcctttag
    16441 cgatgtttca gaagtttatt atcgggaatt tatacggatg gcgaaagaaa acagatcatt
    16501 ccttaagacg ctttagaaaa gctatgattt cggttgctcg taaaaatggc aaaacaattc
    16561 tgatagctgg tatcttgctt tatgaatttt tgtttgggca taatccatct atgagtagac
    16621 aattgttttg tacagctaat gaccgtacac aggctaaaat tgcttgggac atggcaaaga
    16681 agcaactctc atctttaaga gcaaaggacg ctgatgtcag aaaagccacg aaaattgttc
    16741 gtgatgagct gaaaaactta catgatgaat cttatattag ggctcttagt cgagatactg
    16801 gggcagtcga tgggttcgag ccttacgttg gcgttttaga tgagtttgcg gcatcaaaga
    16861 caaacgaaat gttagagctt ttagaatccg gtcaaggtca gcttgataat ccgtttatct
    16921 tgattatctc aacagctggt atggatttga atgtccccat gcacacaatt gagtatccgt
    16981 acatcactaa aattttagac gaagaaattg tagatgatgg ctattttgga tatgtcgcag
    17041 agcaagacaa cgaaggtgaa attaaagatg aatcaaattg gataaaatca aatccaatcc
    17101 tcgaggttga agctttgcac gataagctaa tggattacct gagaacgcgt cgtagagtgt
    17161 ctcttgaaac aggtgaaatt aacaaggtac ttatcaaaaa ctttaacatg tggcggcagt
    17221 cgagtgagga atcatatatt gataagcaat cttgggaact tgctcgtatt gataaacccg
    17281 acacacataa acgaagggtc tggctaggtg tggacgtcgg tcgtgttagt gacttatttg
    17341 ctattacacc agttattatg atggacgatt tttggtatat tgacagtttt tcttttgttg
    17401 cgacaaagta tgggttaacg gctaaagaaa agcgtgatgg tgtgtcttac agtaatttag
    17461 aacgtcaagg ctattgcgag ataacaacat tagaaagtgg ggttattgat gatgagagag
    17521 ttttagaaaa aatagaggag atggtctatt cgaatgactg ggaagttaac ggaatctgtt
    17581 ttgaccctta ccaatttgga acgctgctta cgatgattga gaaaaggcac ccagaatggc
    17641 ctctcataga ggtttcgcaa acgacaatgg ttttgaacat gccaacaaag caatttcgtg
    17701 atgatctcaa gaatggcaaa ataaagcact ctggcaatcc attgctaaca atggctgtta
    17761 ataacgctta tatcaagact gataacaatg gcatgaggat tgataagaat aagaatagca
    17821 ataagataga ccctctggac gctgctttag acgggtatgc agtttgttac ttagagccat
    17881 ttgacggctc tggttactgg acaagtgaga aaattttagg aggagagaca ctgttttgat
    17941 tggttttatt ttaaaaaaca tacatacatt aatcttgtta gctggactag gtttattgat
    18001 gtatgggttg tttttgtttg gtgataaagt tggttttatc gctagtggtc ttattttaat
    18061 ttttttagct atctatgtag atagcgtagg aggaaaacat gaataaacgc attaagaaaa
    18121 aacgtaaatt ggaaacagcg gttgtgatgc ttgttgcaga aaatgctatg caagctgaag
    18181 tactcaggaa tcaaaacaga caaattgcag agctgagatc gattatacaa caaaacgccc
    18241 aagcgacaaa tagagagttt gcagcagtta aatcagcgac gctagacaac caagcagcca
    18301 ttaagaaaat tggggatgag gtttattata tcaagcaaaa ttataagcgc aagtggcgga
    18361 aatagatgtt aatggtttag aaaggaggtg agaaatcgat gagttttttt caacctttgg
    18421 gcagttcaaa ggtgtcctat gatgactatg tatcatctgt tttagctggc gatgtctccc
    18481 aaaaatactt aggagtgtcg gctttgaaga atagcgatat tttaacagca acgtctatta
    18541 tagctgggga tattgctagg tttccgcttg ttaaaaagga tgttaatggg gacattatcc
    18601 atgatgagga tattaattat cttttaaatg ttaaatccac aaaaaatgcg agcgctagga
    18661 cctggaagtt tgctatggca gtaaatgcca ttttgactgg taattctttt tcgcgtattt
    18721 tgagagatcc aaagactaac caagctttgc aattccaatt ttacaggccg tcagaaacga
    18781 ctgttgagga gacagataac cacgagatag tttatacgtt tactgatatg ttgacagcaa
    18841 aacaggttaa atgttttgcc catgacgtta tccactggaa gttttttagt cacgatacaa
    18901 ttttgggaag gtccccgcta ctgtctttag gtgatgagat tgatttgcaa accggcggca
    18961 tcaatacctt aattaaattc ttcaaagatg gtttttctag tggcatctta aaaatgaaag
    19021 gcgcttatat aagcggtgaa gcacgtaaga gagccagagt tgaatttgaa aaaatgcgcg
    19081 agggtgcaat tggtggtagt cctttagtat tcgacgatac gcaagaatac acgccgcttg
    19141 aaatcgatac taacgtattg caattaatta caagtaacaa tttttcaacg gcgcaaatcg
    19201 caaaagcttt gcgggttccc agctacaagc ttggtgttaa tagtccaaat caatctgttg
    19261 cccagttgat ggaagattat gtcacgaatg atttgccatt ttattttgat gctatcacaa
    19321 gtgagttagg acttaagacg ctaagtgata aggataggcg tttgtatcgt atcgagtttg
    19381 atacacgaag cgtcacaggt cgcaatgttg atgagattgt caaattggtt aataaccaaa
    19441 tcttgacgcc taaccaaggc ctcgtagagc ttggtaagca aaaatcaaca gatccaaaca
    19501 tggataggta ccagtctagt ctaaactacg tctttttaga caaaaaagaa gaatatcaag
    19561 acaaggttgg tatcaaaggg aaaggaggtg aggtaaatgc caaagaggat aaatcttaaa
    19621 ggaccactaa ttgcaaataa ctctcaagaa gtttacgact attacggaat ggaagcagca
    19681 agtgctaaaa gtatcattga gcaatttcct gaagataata gcgatattgt tttggaagtt
    19741 aattcaaacg gtggacttgt gacagttggg agtgaaatct ataccgcttt acgaaattac
    19801 aaaggaaaag taactgcaga aattactggc atggctgcaa gtgcagcatc tgtggctgtt
    19861 atgggtgcgg ataaggttgt catgagtcct acagctcaaa tgatggtgca taaagcactc
    19921 tttaaatggg tgtctggtaa tagtgatgac ctagacaaag cttctaatgc cttaaaatca
    19981 agtgataaag ctattgtgag tgcctatgtc gcaaaaacag ggttatcaga agatgcaatc
    20041 atggatttaa tgcgaaatga aacgtttatg tccgctcaag atgccgtaga aaaaggtttt
    20101 gcggacgaag ttatgtcttt tgaagcagtt gctagcattg ataattccat gttgccgcaa
    20161 gctgttattg atgactatta cagaagtagg aacaaacgaa aacaagagat tagcaacatg
    20221 ttactagaaa ttgaaaaaga agaaatttta cgagggctat aagctctttt tttattggag
    20281 gaatttatgt tcgaagaaaa aatcaaagaa attaaagcga atatcgctaa tttaaaccaa
    20341 gctattgcta ctaaaacaac agaagtaaaa aatgctttgg aatcagatga ccttgaaact
    20401 gctcgctcaa ttaaagcaga aattgaagaa gctaaagcaa acctagcaga agcagaaaat
    20461 gacttgaaat tgtatgaagc tagcgttgaa aaaggcggtg cagaaaatac tggaggaaaa
    20521 gaagtgccac aagaaactaa aacatatcgc gaaagcgtta acgaatttat tcgttcaaaa
    20581 ggaacagtaa ccaacgaagg tttgcgtttt gaagggaaag acgaggttct tatcccactt
    20641 aaccaaacaa cgcctgtaga ccctaaaacg gatggtgtta agaaaacgga tgtaaaacct
    20701 gtctctagtg aagaaattct ttacacacca gcgcgtgaag tcaagacagt tgttgatttg
    20761 aaacaattca ctagcatcca cccagctaaa aaagaatcag ggaaatggcc agtattgcaa
    20821 cgtgctacag aaaaaatggt tagcgttgaa gaattggaaa aaaatccaaa actaggcaaa
    20881 ccacaattta aaaacgttga atgggaagtt aagacttatc gtggagctat cccactgtct
    20941 caagaatcta tcgatgatgc agatgtagat ttggttggta ttgttgctga aacaatcggt
    21001 caaatgaaag ttaatacaac taatgatgca attgctaaag tcctaaaaac atttgaggct
    21061 aaagctggtg tcaaaacatt agatgacatc aaaaaaatcc taaatgtaga tttagatcca
    21121 gcttacaatg tatcatttat tgtatctcaa agtttctatc aaaccctaga tactttaaaa
    21181 gacaaaaatg gtcgctactt gcttcaagac tcaatcacct ctgcgtctgg caaagtgttc
    21241 cttggaaaac cagtatttgt cctatctgat gacgtgattg gcgaagactc agcttttgtc
    21301 ggagatttta agcgaggcgt gttattcgct gatcgtaaag atttagggct tcgttgggca
    21361 gataacgaaa tttacggtca atacttgcaa gctgtccttc gctttggtgt cgctaaggta
    21421 gatgacaaag ctggatacta tgtgacattc aaaccagaac aattgccctc ataaggccac
    21481 tgaagaagtg gcgaaaccaa ctagcaaaag cactgtcgag gagattaagc gctatttaac
    21541 aagcaaggga attgacttta atgggaaaac attaaaatct gatttattaa aacttgcagg
    21601 cgttgaagag gtatagctat ggctgtatca aaagagttat tagacagtgt aaaactctat
    21661 tgtaaaattg actttgattt tgatgacgac atcatcaaag aaatgattga atctgctcaa
    21721 gaacaaatct gttttgcaat agaagacggt tctactcctg aaaagttcaa aggtcacgct
    21781 aaatttaatt tagctgtcaa aaagcaagtc aaggaagagt atgaccatcg cggtttgtct
    21841 gcggatagtt ttcgctatcc gttggcaaat ggtgttttaa acattatcca tcaattgcga
    21901 ttgagaggtg atgattcgtg attacacgca agatgaacgt caggataacg atttttagcc
    21961 aatcaggcgg gcaaaatgaa gatggtgaag tagtatctgc tgtcagaaag gacttgtata
    22021 cttgttgggc agaagtgcta aaaacgcagt tgagagattt taattatcaa tcaaagtatc
    22081 aaaacgctag caatttgcca acaaataagg atactaaggt ttttttaatt aggtataacc
    22141 ctgaattatc tatagataac acgatgtttg ttgagtttgg caagcgcatt tataagatag
    22201 ataaaatcga atctgacgaa tctggcaaag atattatcat gataagtgga gtaagcatgt
    22261 catgacaaaa ggtttagatg aaatattggc taatctgaca aagcttgaag taaaagcacc
    22321 aaaaaccgca aaagcagcag taactgaagt tgccaaagaa tttgaaaaag cacttaaagc
    22381 aaatacccct gtttatgaga ttgaaacaga tgagcggcta caggaagata ccgttatcag
    22441 tggttttaaa ggagctaatg ttggaattgt atccaaggaa atcggctatg gcaaagcgac
    22501 tggttggcgt gcgcactatc ctaacgatgg gaccatttac caacgcggac aagactttaa
    22561 ggaaaaaact atcaatcaga tgacaccaaa agctaaacaa atctacgcag caaaagttaa
    22621 ggagggacta gggctttgat tgctgaaaca gcagcttata aattattaag taacgataag
    22681 acgctaaatg agttgttgga taggctcaga ggcggtcctt ttaaaaatgg gtttaagcaa
    22741 ggcatattta cttatgatat tccagataac ccagttgact tgcgtaaggt agatttagcg
    22801 ccttttatgc gaatcaacac aacattagac ggtcctgctg attatgcaga tgatgagata
    22861 ctgtgtaacg agcaacggat caccatcaat ttttggtgca aaacagcttc tgaagctgac
    22921 caaattagca aatgtataga tgatatttta aaaaaaggcg gttttgaaag atacaccgca
    22981 aacgaaaaac caagatataa agatagcgat attgacttac tcatgaacgt aaggaaatac
    23041 cgctattttg atttttattt aaaagaaaga ggaaaaaatg ggaaaagtaa aatttggact
    23101 acgtgatttt cagtacgccg tactaggcga agatgataat gttgcaacga aaaaaggtgg
    23161 tattaaaaaa ctacctggaa tgaaatctgc aaaactcgat attaccaatg aattggttac
    23221 cgtttcggca gatgatgggc cttatgtagt gctttcggga ggaatcaccg aaacaaaact
    23281 agaaattgaa gtactcgatc ttacaaccga tgcacgtaag gactttttcg gcattaaagt
    23341 ggcggcaggt gttgaaaaat ataacaaaaa cttgacacct aataatgtag cctgcatttt
    23401 tagaacaagt gatgagaacg ggaaggctat ttgggtagga ctgcttaaag gtaaatttaa
    23461 tttacctggc atggaaactc aaacaaaaga aggatctcct aaccccaaag ctgataccgt
    23521 aacaggtaac tttgtgtctc gtggcaccga tggagacgtg cttgttattg gaagagaaga
    23581 aagtcatgaa tttaattatg aagcttttgc aggatttgtt tttgctggtg cgacagatat
    23641 taaaaaaggc gaaaacttcg aaatgtaaca atcaggttgg attttaaatc caacctttta
    23701 tttttgataa ggagtagata tgtacgaaat taccttaaaa aaaggtggtg tagataaagt
    23761 tttttcaaaa gactttatta acgttgagga taatttgttg gctgttgagc atcaagttag
    23821 acaaagcgct gtgtttagcg atgagaaaag acgcttagat tctaaagcgc atagaaaact
    23881 taacgaatct tacttgcaaa tgtttgttga tatgtacgca ggtcaattta cagtcgatga
    23941 tttaaagcaa tctgacatga gtgttttaaa tacacttaat gacctgtaca ttgcagcact
    24001 cggtggagag caagaggaag acgaaagcga aaaaaaggaa caataacccc acaagaggct
    24061 aaagaaaact tactcttgtg gatacagagc cttttgaaaa acggttatac cattttagat
    24121 attaaaaaaa tgcgcttatc tgatattgaa ttgatggtac aagcgctaga aattgaaact
    24181 gtcgaaaaag aagaagtgat tgaaacgacc ttggataagg cattcccatt ccttttcggc
    24241 tagaaaggag gctaaatggg gaatataggt gatttagtag caacggctac actagacata
    24301 tcaccattta tgtcaaacac aagaaaccta aaaacctaca tgaaaggctt agacaactcg
    24361 ttaaaagctg ttgaaaagag ttttcaaggg catggcgggc ggattaaagg tcttaaagcg
    24421 gtctatgctg aaacaggtag tgcattaaaa ggttaccaag aattactaaa aactcagtca
    24481 caaaaatata gcgacctaaa aaaagagata ggcgatgtta ataacgctac tgctgagcaa
    24541 aagcaaaaat tgattggcgc taaatcagcc atgttggaga ctgctgcgaa agtcacagaa
    24601 ttgcaaaaca gattacgagc gttagccact gaaactagcg tttttacaag atttggtaaa
    24661 gctgctgaaa aaatcggcgg caagatgaaa tcattaggtg attctgtagc aggagttggt
    24721 gctgcattta cgagaggagt taccgctcct attgtagcgg gcgctggtta tgctattaaa
    24781 gcagctgttg actatgaaac tgcgtttgcc ggtgttaaaa aaacagttga tgagacggcg
    24841 acagtatcct atgctaagtt gtcgcaaggc attaggcaaa tggctaaaga gttgccagcc
    24901 agcgcggtag aaatcgctca cgttgcagag gcggcaggtc aattagggat taaaacaggt
    24961 gatatcctta gtttttctcg tacaatgatt gatttaggag aatccactaa tctatccgca
    25021 gaagaagctg catcatctat tgcgaaaatc gcaaacatta caggactaac gtcaaaggaa
    25081 tattctagat ttggtagctc tgttgttgcc ttaggtaata actttgcgac aactgaaaga
    25141 gatattgttg cgatgacaaa ccgtatcgcc gcatctggta aacttgccgg cttaactaat
    25201 caagaaatgt tagcgttggc aactgctatg tcaagcgtcg gtatcgaggc agaagctggt
    25261 ggtactgcta tgactcaaac attatcagca attgaaactg ctgttattaa tggtggagaa
    25321 gatttaacaa aatttgctca aattgccaat atgtcatccg ctgattttgc aagagcgtgg
    25381 aaagagaagc caattgttgc attgcaagag tttattaagg ggcttggtca acttgataaa
    25441 aaaggtgaaa gtgctacaaa agtgcttgat gaactcggtt taagtggtat ccgccagtct
    25501 aacatgttga aatctttagg attagcatct gagactttag gcaaggctct tggaatctct
    25561 aacaaagctt ggcaagaaaa cactgcttta actgacgaag ctaataagcg ctatgagaca
    25621 acagagtcta agctaaaaat gcttaagaat gaagttaatg atgtagctat tgaatttggt
    25681 ggccctttgg ttgacgctct aagaaatggg ctcgaagcag gaaaaccaat tattcaaatg
    25741 gcagcagatt tagccaagca atttaactcg cttgacaaag agcaacaaca gcagattatc
    25801 aagtggggac ttattgctgc cgccgctggt ccagctttgt ctatctttgg taaaggtgtt
    25861 ggcattattg gcagtactat tcaaggcatt gggaaaatga gtcaaggttt aggagcgttg
    25921 tcaggctggt tgcgcacttt taaaactgga gcggcagcag ctagtgcagg agccgaagct
    25981 gccacagctt ctatgggcgg aatggctggc gcggttgcct tattaagcaa cccagtaacg
    26041 tggggtgttt tgctaggtgg ggcagccatt gtgggtatag gtttaattgc tgatagcatg
    26101 tataaagccc aaaaacgcac agaagagtgg ggaaccgctg tttccgcgac agaagcaaat
    26161 gcactaagta actttaagaa aaaagttgac gaaactaaca cttcgttgca aatgttcgag
    26221 gcaggcgcag gtagcgttaa gaaagtgact gaagcttttg atgatttggt cggaagtatt
    26281 gaaaagttag ctcaatcaaa attagataag aatataaact tagctaaaaa attaggatta
    26341 tcagaagaaa ccataaatgc tttgaaatcc aaaactgaat cagtggttaa caatgttaaa
    26401 agcatgaata cccagattaa agcaatcatg gagaaacaca acggtgacat gagccagttg
    26461 tcaagcgctg aaaaagaact tgttttgcga aatcaaagag aaatgattac cgctcaactt
    26521 gatttaatga agttctctgc atcagaaaag aaagctttaa cagcagcttt gaataacgaa
    26581 ttagatgccc tcaacgcaag acagttggaa aaagtatccg aaaacaccgt taagatgctt
    26641 gataaagaaa attctgctta caaaacaaaa aaagcagaat taaaagaaat tttaaagcaa
    26701 tttggaagcg atactagcaa gctaagcgct gaagaattgg ctgctagaca ggaagttttg
    26761 aatagactta ctgagttaaa tatgcagcac aacctaaaaa ccaaagcttt gaacgatcag
    26821 taccttgcta tccagaggga gcgtgtccaa cggttaaaag aatctggcaa gagtcaagaa
    26881 gaaatccacc aagggattag ccaaatggca tcagacatgg ctcagaagct tggtattagc
    26941 tatgacgatg cttaccgtaa actagcttat tatactgaga aatctggtga aacgttgaaa
    27001 gttttgtcgc gtaatacggc taatgctacg gcggaagtag cagcagctaa cgctcagtgg
    27061 gatagcttgt ttacgagcga taatccacaa caaagcctaa acgaattgtt atcgaccgca
    27121 gaaggctgga acagttttga aatcatggtt aagaatgccg acgttgaacc gacaggtaga
    27181 gccgcacttg ctgaaatgtt ggtagctggt ggccaatggg aaaacatgac gttagagcag
    27241 aagaagttgg ttgttgatgg tcaacaagcg atgattgaaa tctttgatag caaggagtta
    27301 ttagcgcagt ggcaagcatt gacgccagaa gaaaaggttt tgctagcgaa aaacttaaca
    27361 caagaaccaa ctatgtcggc tcaacaagcc cttgacagtg tcaagcaaac agtacctgct
    27421 gatgttaacg caagtgataa aacagcaggc gaaactcaat cagcacaaaa caagattgac
    27481 aatgttaaac aacgagttcc agctgatgtg aaagcatcgg ataagactgg accagatgta
    27541 gcaagtgctg acagggctgt caatagtcct aaacaaaaaa gtccagctgt tatcagagcc
    27601 caagataatg ctagcggtgt tgcagaaggt gttataggtg cattggctag aatcccaaga
    27661 agtgttacaa caaccattac aacgtttgtc cgtaagattt ttggacatga aaaagggact
    27721 gatttccacc ccggcgggtt agctatggtc aatgaccaaa aagggccgct atacaaggag
    27781 ttggtcactt taccaacggg tgaatcattt attccaagcg gacgaaatgt catcctccct
    27841 ttgccaaggg ggtctaaagt cttaaaggcc agccgtacaa aacaattatt cccgcactat
    27901 gccagcggaa taggttttga tgacaccaaa atcgctagtc tgacaactcg tcttaaatct
    27961 gtgcaagata aggggcaagt gattatcaat accgaccctc aacttgcgga gttaattaaa
    28021 ctacttaaag acagagatga cagaaatgtc acaaataact ataccgtaaa cgctactaat
    28081 agtagtagtt cagaggatat gtttagccaa gaaaatatga gacggctact cagagaatta
    28141 gcttactaca cgaacggaga aggagggagg ttagcttaat gcgatacatt gaatttaatg
    28201 gcactaaaag caatgattta ggtttattgc tagagcgcga acgatcaatt aagtcaacaa
    28261 acaacgacat tgatttaatc gaagtagcag gtcgtgacgg tgtacttatt aaagacaacg
    28321 aacgcttaaa agcggttgag caagactttc ctttttcgct ggttggtgac gtgactgtca
    28381 atcaacaaaa aataagcgaa tggttacatg tcaagggttg gcacgacttg gcgttgtctt
    28441 gggacaagga ttatatctat cgggctagtg ttgtcaatct ttttgaaata gacgagatac
    28501 ttaagcaatt tggtagatta aaagttaatt tcttaatcca ccctatcaaa tatttaaaaa
    28561 caggtaagca agaggtgcct ctcgtaaatg gaggtactct acaaaatcct ggcaatgtcc
    28621 aagctaaacc tatcttaaaa atcaaaggca caggcaatgg tgttttaacc attaatgact
    28681 ttgagacagg acttgaaaat gtacagggcg agcttgttat agatatggaa aggcatcttg
    28741 tctataagga tgttttatcg gcttgggata atatcgtaag gacagaacat catcgcatgc
    28801 ctctttttga tattggtcaa aacaaaatct catggactgg taactttact atcaccgcag
    28861 tgccaaactg gggggttaaa gtatgatacc agttttatac gaggccaaag aaaccaaatt
    28921 taggactttt ggccttggag aaattgcgga cgcttacgag gttaaagcta cacgtgagcg
    28981 taatggcaat tactcgttat atatcaaata tcctttagat ggtgcctttg ctcatctgtt
    29041 caaagaagag atgaagatta agtccgatgc tgggcgtagg actaagtggc agacgtttga
    29101 gattaatcgg gtgctgcgga atagtaaaga gcacattgag atttttgcac gccacatatc
    29161 gatgcgcaca caggacatcg ctttaaaacc atttgtgagc gggtctagca ttgacgcaga
    29221 gtcggcactg gaggtttggc gggataatct tgtcggtgat gatacctttg atgttaaaag
    29281 cgacatttta acactaggca gctttaactg ggaagttgac aagataggca atgcaagagg
    29341 cgctctcggg ggtgtcgctg gctctatctt agatgtttac ggtggtgagt acgagtttga
    29401 caatcgcaca atcatcttac ataaacaaat ggggcgtaag acccctacgg ttttggagta
    29461 tggccgcaat atcgttagcg tggaagagga gcgtttgctt gatggcaatt atacctcaat
    29521 ctatccttac gtaagatata cgccacaacc aaagccgcaa gaggaagcct ctggtaagcc
    29581 gcacatcggc gagcatgaga aacccgaaga acagctggtc actttgcctg aatttatcat
    29641 agacggtcag tatcttgact tatatgccca acgcagaata cagatggttg atttatctag
    29701 tcattttaat gatgacaaaa aagagccaac agtcgaagaa attagaaagc tggctcagaa
    29761 ataccttaaa gataataatg taggcgcacc taaaatcagt atagaggttg attatatcga
    29821 cctgtcacag acgcttgact atcaagattt tagagttatg gaggaggtcg agctttgcga
    29881 tattgtaccg ctttactatc caaagtttgg tatcacaacc gagaccgaaa aagtcgttga
    29941 gattgtctat gacgtctata cagatagcaa tcacacaata aagcttggca cgattggcca
    30001 atccatctct aagagtctga caggtggtgt tacgcagcgg attgagacgc tggaaaacaa
    30061 ccaaaaggtt attactaata atcaacagca atttgagctt aatttaccca aatacctcaa
    30121 cgatctaaac ggtaccaaga tatggtacga aaaaccagat gacaacgttg agcacaagat
    30181 aggcgatttt tggtttgaga aaaacggtaa atatcagcgt acctgggttt gggacgggaa
    30241 tcaatgggta aaaatcattg atactgagga tttaaatcct aatcagcgcg cttttgatga
    30301 ggctatggcc gagatcgaaa agcttaagca gcaccaacaa caaattgaca aacgcaatca
    30361 gcg
//
LOCUS       DARYNN010000026        30235 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.026, whole genome shotgun sequence.
ACCESSION   DARYNN010000026 DARYNN010000000
VERSION     DARYNN010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30235)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30235)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30235
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.026"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(<1..134)
                     /locus_tag="TVB59_001109"
     CDS             complement(<1..134)
                     /locus_tag="TVB59_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HEL1010010.1"
                     /translation="MKSIIEHYQARPLGEERCYAVCLPLIWQEGRWQVLYEIRSQHIS
                     "
     gene            336..662
                     /locus_tag="TVB59_001110"
     CDS             336..662
                     /locus_tag="TVB59_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019314866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEL1010011.1"
                     /translation="MYFPVSATLIEFLILSIVDKHDSYGYDISQTIKLVANIRESTLY
                     PILKKLEKSDYLTTYSQEHQGRKRNYYTITAKGEKQLIFLKEEWQSYKATLDGIIEGR
                     LRHDKR"
     gene            649..1074
                     /locus_tag="TVB59_001111"
     CDS             649..1074
                     /locus_tag="TVB59_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010012.1"
                     /translation="MTRDEYLAELDKYLRKLPKADYYEAAENSSQLELNDGSIKDSSI
                     TVADTKEENDYDYTDPSELAINHVTIKEKNTINGGDININTTLANPRDIAYHVTTRGN
                     IKLSSRFSNAKLNTDAATGATSFHSDIANTVNQSDLSIH"
     gene            1093..2148
                     /locus_tag="TVB59_001112"
     CDS             1093..2148
                     /locus_tag="TVB59_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HEL1010013.1"
                     /translation="MTKQDFLDKLKQQINHLPQKDYQEIIDHFTEYFDEAGPDHEQAI
                     LKELGNPEDIAKELLKALDLPEKTDEDDWTNWEVDNKTKSEASSQKLEPIVDIRYSLL
                     NHDLTIETADIPYPTISYDDNRITISQDSDGMLNIIEDSAVQTIQYGFHFLDRWLAKY
                     QPITLTLPVNHHLKKISGESDNNDVTIRHIHCDSIVSNTYNGTISISHLSDSTVNLSS
                     KNGNIILEHCNIQSSKCQAKNANLSCDNSTLINCQLNNNNGNIRLEASQLTETFIENK
                     NGNIIGQQLSFSNDITIINKNGIIDINCPRENLIYYDVKASNNNGFVTISQEAGRQTP
                     FKAQLTISNNNGLISVS"
     gene            complement(2252..4534)
                     /locus_tag="TVB59_001113"
     CDS             complement(2252..4534)
                     /locus_tag="TVB59_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HEL1010014.1"
                     /translation="MLEGLKAIIKNRKLVVTMIGVALVPALYNLSFLGSMWDPYGRVD
                     QLPVAVVNQDKPAYLNNKRLTIGNDMVDNMSKNKELDYHFVAADTAQKGLEKGRYYMT
                     ITLPKDLSQKATTLLDQQPEKLIVSYQTSKGHSFIASKMGESAMNHLREAVSKNIRKT
                     YITSVFKSMHQLQSGLKEASNGGQQLAAGLVIARASSQLMSRHLNTLSESSARLSQGA
                     GNLSSGIAAYTAGVGQLDTAGLGQLAADMPAYLDGVSRLSKGANQLNAGLTQLALGSD
                     LSQDKQANIQALMASLPKLNQAIQQLKTNLSLSLAPNVDSGAIAKHLADMTRLVQELV
                     VDDTADKNNQLAALQATATYQGLNSEQQEELSSAISNTSTKVTISAKAMLTSLQAMSE
                     ELEAMSTSAGVADQLRDFKALVNQLAYQADQILPSTGKALSELSTGLRAVHSATTAQL
                     LSGSQALAGGFNQLTAKNEALTAGLSTLATGATALNHQSSQLLAGGQQLTVGANQLAF
                     GANQLSSGSSQLTDGLTTLSTGLSSLTTSLSKASDQLSMAWVEDQNADMVSDPVALSE
                     KDKDKVRTNGIGMAPYMIAVSLMVVALSTNIIFAEALSGKPIKDRWDWAKQKLLINGM
                     ISTVGSVILYAALQLLGFEANDGIKTLGFIMLSGWALMALVTALVSWDARYGAFASLI
                     MLLLQVGAAGGSYPIELSGQIFQILHPYLPMSYIVSGLRQTISLTAQIGLETSVLVGF
                     LLSFMAIGVLIYRPKDKQSS"
     gene            4666..5199
                     /locus_tag="TVB59_001114"
     CDS             4666..5199
                     /locus_tag="TVB59_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEL1010015.1"
                     /translation="MDSRKQQTKKAILNAMVSLLKTESFDDVTTVQLAKMAGISRSSF
                     YTHYKDKYEMIDYYQQTFFHKLEYIFEKEYQNKEHAFLEVFEFLKREQLLSALLSSNG
                     TREIQSFIINKVRLLITTDLQDKFSKDILSPTEKEYRSIYLAHAFFGVCQSWIAKGKK
                     ESPQEMTRFVLKMLSKT"
     gene            complement(5406..6017)
                     /gene="rpsD"
                     /locus_tag="TVB59_001115"
     CDS             complement(5406..6017)
                     /gene="rpsD"
                     /locus_tag="TVB59_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEL1010016.1"
                     /translation="MSRYTGPSWKQSRRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFSYGMGEKQFRNLFVQATKIKEGTLGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSFRVEIGQVISVREKSMKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(6541..6813)
                     /locus_tag="TVB59_001116"
     CDS             complement(6541..6813)
                     /locus_tag="TVB59_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HEL1010017.1"
                     /translation="MSDAFTDVAKMKKIKEDIKAHEGQLVELTLENGRKREKNKVGRL
                     IEVYPSLFIIEYQGNPDASGEANNSYVESYTYSDILTEKTLIRYFD"
     gene            complement(6830..8206)
                     /gene="dnaB"
                     /locus_tag="TVB59_001117"
     CDS             complement(6830..8206)
                     /gene="dnaB"
                     /locus_tag="TVB59_001117"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEL1010018.1"
                     /translation="MEVLSLPEVAELRVQPQDLLAEQSVLGSIFISPDKLITVREFIG
                     PEDFYKYSHKVIFRAMIRLSDRNDAIDATTVRTILDDQGDLQHIGGLSYIVELVNSVP
                     TSANAEYYAKIVAEKAMLRDIINRLTETVNLAYEGASDSEDIIASAEKALVDISEHSN
                     RSGFRKISDVLKINYENLEVRSKQTSDVTGLPTGFRDLDKITTGLHPDQLIILAARPA
                     VGKTAFVLNIAQNVGTKQKRAVAIFSLEMGAESLVDRMLAAEGMVNSHSLRTGQLTDQ
                     DWNNVTIAQGALAEAPIYIDDTPGIKITEIRARARKLSQEVEGGLGLIVIDYLQLITG
                     TRPENRQQEVSDISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIE
                     QDADIVAFLYRDDYYRKESDSTEEALEDNTIEVILEKNRAGARGTVKLMFQKEYNKFS
                     TIAQFEER"
     gene            complement(8227..8679)
                     /gene="rplI"
                     /locus_tag="TVB59_001118"
     CDS             complement(8227..8679)
                     /gene="rplI"
                     /locus_tag="TVB59_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEL1010019.1"
                     /translation="MKVIFLVDVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEASSQAI
                     GQLRGQQKAEEKAQAEILAEAKAVKKILDDEKTRVQFKEKVGPDGRTFGSITAKKISE
                     ELQKQFKVKVDKRHIVLDHPIRAIGLIEVPVKLHKEVTAEIKLNIAEA"
     gene            complement(8676..10652)
                     /locus_tag="TVB59_001119"
     CDS             complement(8676..10652)
                     /locus_tag="TVB59_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEL1010020.1"
                     /translation="MKRFRFETIHLIMMELILFGLLALCVRIMQSKMLITLAIFLVLL
                     FVAALLWYQKKVYELSDLDHIELLNEQTENNLKTLLDNMPVGVIQFDQETNAIEWYNP
                     YAELIFTDEAGFLQEQMIQQLLTDKRKSDISQTFEVSGNRYTSYIDVASGIFYFFDSS
                     VGSRQSADSSLLKPVIGIISVDNYDDITDDLSDADTSKINSFVANFIAEFMESKQVFY
                     RRVNMDRFYFFTDYKILKGLMDDKFSILEQFRKEAQEAQLPLTLSMGISFGEENHCQI
                     GQVALENLNIALVRGGDQIVIRENADHTNPVYFGGGSVSTVKRSRTRTRAMMTAISDR
                     IKMVDNVFIVGHRKLDMDALGSAVGMQFFASNIIENSFAVYNPDEMSPDIERAIERLQ
                     ADGKTRLISISQAMGLTTPRSLLVMVDHSKISLTLSKEFYEQFQDVIVVDHHRRDDDF
                     PDNAILTFIESGASSAAELVTELIQFQNAKKRLNKIQASVLMAGIMLDTKNFSTRVTS
                     RTFDVASYLRSRGSDSVEIQNISATDFDDYKQVNEIILRGERLSDSIIVATGLAGQYY
                     SNVIASKAADTILSMAHIEASFVIVETGADKIAISARSRSKINVQRMMEKLGGGGHFN
                     LAACQMKHISLSEAKQLLLETIDNTMKETREVES"
     gene            complement(10740..12638)
                     /gene="mnmG"
                     /locus_tag="TVB59_001120"
     CDS             complement(10740..12638)
                     /gene="mnmG"
                     /locus_tag="TVB59_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEL1010021.1"
                     /translation="MVHEFTESYDVIVVGAGHAGVEASLAASRMGCKTLLATINLDML
                     AFMPCNPSIGGSAKGIVVREIDALGGEMGKNIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KSLYAREMKHTVEKQENLTLRQSMIDDILVENGRVVGVLTATGQKYAAQAVIITTGTA
                     LRGEIILGELKYSSGPNNSLASVTLADNLKKLGLEIGRFKTGTPPRVKASSIDYEVTE
                     IQPGDVTPNHFSFMSKDKDYLANQIPCWLTYTNQISHDIITKNLYRAPMFSGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGFDTEEVYVQGLSTSLPEDVQKELVHSIKGL
                     ENAEMMRTGYAIEYDIVLPHQLRATLETKMISGLFTAGQTNGTSGYEEAAGQGLVAGI
                     NAALKVQGKPELILKRSDAYIGVMIDDLVTKGTLEPYRLLTSRAEYRLILRHDNADMR
                     LTEIGRQIGLVDDERWSAFEIKKNQFDNELKRLDSIKLKPIKETNARVQKLGFKSLTD
                     AMTAKEFMRRPEVDYATVVSFIGPAAEGLDAKLIELLETEIKYEGYIKKALDQVAKMK
                     RMEEKRIPKTIDWDAIDSIATEARQKFKKINPETIGQASRISGVNPADISILMVYLEG
                     NGKARRKT"
     gene            complement(12641..13105)
                     /locus_tag="TVB59_001121"
     CDS             complement(12641..13105)
                     /locus_tag="TVB59_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HEL1010022.1"
                     /translation="MVQDFRTRIADHSFGVRASALIIKDGYIYLAKSPKEDYYLLGGA
                     IHVGESTEEAVKREVLEEVGAEVSVAQLAFVVENQFCLEGVNFHQIEFHYIVSLLSDS
                     SPSVVEGDCTRVCEWVALDDLDKIRLNPSCLKRAIKHWDRQPQHIKHIEIKE"
     gene            complement(13310..14434)
                     /gene="mnmA"
                     /locus_tag="TVB59_001122"
     CDS             complement(13310..14434)
                     /gene="mnmA"
                     /locus_tag="TVB59_001122"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEL1010023.1"
                     /translation="MMTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGVFMKNWDD
                     TDEFGVCTATEDYKDVAAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRSGRTPNPDV
                     MCNKEIKFKAFLDYAMTLGADYVATGHYAQIKRDENGVVHMLRGLDKGKDQTYFLSQL
                     SQEQLQKTMFPLGHLQKSEVRAIAEQAGLATAKKKDSTGICFISEKNFKTFLSHYLPA
                     QKGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQQGGDNKPWFVVGKDLSQNILYVG
                     QGFYHESLMSTSLDASVIQFTREVPEEFTLECTAKFRYRQPDSKVTVHVKKDKAKVVF
                     AEPQRAITPGQAVVFYDGHECLGGGIIDMAYKDGEPCQYI"
     gene            14715..15386
                     /gene="sdaAB"
                     /locus_tag="TVB59_001123"
     CDS             14715..15386
                     /gene="sdaAB"
                     /locus_tag="TVB59_001123"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEL1010024.1"
                     /translation="MNTQKFQSVFDIIGPVMIGPSSSHTAGAVRIGKVVHSIFGEIPD
                     EVTFHLYNSFAKTYQGHGTDKALVAGIMGMDTDNPNIKNSLEIAHQKGIKIYWDILKD
                     SNAPHPNTVKISVKKADKAMSITGVSIGGGNIQVTELNGFSVSLSMNTPTLIIVHQDI
                     PGMIAKVTDILSASDINIAQMTVTRESAGEKAIMIIEVDSRDCQVAVKQIATIPNLHN
                     VNFFD"
     gene            15398..16270
                     /gene="sdaAA"
                     /locus_tag="TVB59_001124"
     CDS             15398..16270
                     /gene="sdaAA"
                     /locus_tag="TVB59_001124"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEL1010025.1"
                     /translation="MFYTIEELVKQADDRFDGNVAELMIATEVEMTGRSRAEILSIMS
                     QHLQVMKDSVVSGLTATKSISGLTGGDALKMDHYIKKGKGLSDQTILTAVRNAMAVNE
                     LNAKMGLVCATPTAGSAGCLPAVLAVAIDKLKLSEKEQLDFLFTAGAFGLVIGNNASI
                     SGAEGGCQAEVGSASAMSAAALVKAAGGTAYQASQAVAFVIKNLLGLVCDPVAGLVEV
                     PCVKRNALGSSFALVAADMALANIQSQIPVDEVVDAMYQVGAAMPTAFKETAEGGLAA
                     TPTGRRYSKEIFGD"
     gene            16304..16939
                     /locus_tag="TVB59_001125"
     CDS             16304..16939
                     /locus_tag="TVB59_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase-like protein"
                     /protein_id="HEL1010026.1"
                     /translation="MKAILFDLDGTLVDSSIGILNAFEYTFQKMKIPCPDHSILSSYI
                     GPPLEATFSAFFRNQHDVEVAITHFRDFYRELGIYQARLYSGITELLDNLSQEGLDLY
                     VTTSKYEPMARQMLQDLTISHYFKAILGSISNRCHKLDIVKACLQDFAINKKEAIIVG
                     DTKFDMIGGKQAGITRLGVTWGFGCQEDLQAHGAQYIGHTPQEVIEIIQSL"
     gene            complement(17000..17611)
                     /locus_tag="TVB59_001126"
     CDS             complement(17000..17611)
                     /locus_tag="TVB59_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HEL1010027.1"
                     /translation="MFKQDILKQRYFSFGIVAAAIALLAVVFAFSSENVNTDSYAKAS
                     DTKVVKKHHKTKKSTVAKAATKEQPAEQAEPSSADAAPAQESVASEVASPAVQEAAPQ
                     AQYAATPVAYSNGVILSNGNTAGAIGSEAAAQMAAATGVPQATWEAIIARESNGNPNA
                     ANPSGASGLFQTMPGWGSTATVQDQVNSALNAYRAQGLSAWGY"
     gene            complement(17867..18676)
                     /locus_tag="TVB59_001127"
     CDS             complement(17867..18676)
                     /locus_tag="TVB59_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEL1010028.1"
                     /translation="MDKLILGRYIPGNSIIHRLDPRSKLLAMIIYIIIIFWANNVVTN
                     LLLLAFTLLLIFLSQIKWSFFFNGVKPMIGIILFTTLFQVFFTQGGSVLFQLGIIKIT
                     SLGLSQAILIFMRFVLIIFFSTLLTLTTTPLSLSDAVEALLKPLVRFKVPAHEIGLML
                     SLSLRFVPTLMDDTTRIMNAQKARGVDFGEGNLIQKVKSIIPILIPLFASSFKRADAL
                     AIAMEARGYQGGDSRTKYRLLSWQLKDTLAIILVVILGIFLFCLKSPSRLT"
     gene            complement(18669..19511)
                     /locus_tag="TVB59_001128"
     CDS             complement(18669..19511)
                     /locus_tag="TVB59_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEL1010029.1"
                     /translation="MSIHFQNVSYTYQAGTPFEGRALFDVNLDIVDGSYTAFIGHTGS
                     GKSTIMQLLNGLHLPTTGKVTVAGKEITSQSKNKDIKPIRKQVGLVFQFPESQLFEET
                     VLKDVAFGPQNFGVSQKEAEALAREKLTLVGISEELFGKNPFELSGGQMRRVAIAGIL
                     AMQPDILVLDEPTAGLDPKGRKELMSLFKSLHQSGMTIVLVTHLMDDVANYADFVYVL
                     EAGKIILSGQPKAIFQHIDLLKEKQLGVPKVTAFAQRLAKQGFDLPYLPITLEELREV
                     LKHG"
     gene            complement(19487..20326)
                     /locus_tag="TVB59_001129"
     CDS             complement(19487..20326)
                     /locus_tag="TVB59_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEL1010030.1"
                     /translation="MSNIIEVKNLTFKYKQDQERYTLDDVTFHVKQGEWLSIIGHNGS
                     GKSTVVRLIDGLLKAEAGQIFVDGDLLTEDNVWDIRHKIGMVFQNPDNQFVGATVEDD
                     VAFGLENKGVSHQEMIERVHQALQLVGMEAFKDKEPSRLSGGQKQRVAIAGAVAMRPM
                     IIILDEATSMLDPKGRLELIRTIQSIRQEYQLTVISITHDLDEVALSDRALVMNNGRV
                     ESVSTPQELFARGNQLINLGLDIPFTTSVVNMLKKDGYPIQGIYLTEKELEEQLCQFI
                     SKM"
     gene            complement(20329..20871)
                     /gene="pgsA"
                     /locus_tag="TVB59_001130"
     CDS             complement(20329..20871)
                     /gene="pgsA"
                     /locus_tag="TVB59_001130"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003090075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEL1010031.1"
                     /translation="MIKKENIPNLLTLARIVMIPLFLLITSFSKTVGWHTFAAIIFAV
                     ASLTDYLDGYLARKWQVVTNFGKFADPLADKMLVMSAFIMLVGLELVPAWVSAVIICR
                     ELAVTGLRLLLVETGDKVLAAAMPGKIKTVAQMLSIIFLLCHWTVLGTVLLYIALLFT
                     IYSGYDYFKGASFLFKDTFK"
     gene            complement(20884..21888)
                     /locus_tag="TVB59_001131"
     CDS             complement(20884..21888)
                     /locus_tag="TVB59_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1010032.1"
                     /translation="MRETSLGELLRETRVGKNITLDEIEAKTGISSHYLLAMELDQFK
                     IIPEEKFGHFLKQYADIVGLDFDSLKRLYQLQVSFKKETGTPSVTQIVEEKLSKKRLQ
                     ENSYSEKIAQPEPSRTQPETLVIPVKTSLSSSKSAPTASHFKATDHRRTRETSASRLS
                     RYGNSAKTKKSAFPSALLGLIAVAIVGVIGFAVWKQFDKGQKAKEAEMSFLKSSQSSH
                     STASSSSEPKTVITTEGAENYLIANITKSKEAVDVTVSLTDAESSWISLTNSEIGEAG
                     MTLTKDNPTYSTTLPAETTESLLTLGVTKGVSVAIDGQPLDLSAMTSTDISYITLKIQ
                     "
     gene            complement(21938..23221)
                     /locus_tag="TVB59_001132"
     CDS             complement(21938..23221)
                     /locus_tag="TVB59_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEL1010033.1"
                     /translation="MTSLLKKDYPSIKETLHYGQLANGLRVYLIKKEGYSEKTAMLTA
                     RFGSLDTSFTVNCQRFDLPSGVAHFLEHKLFEDKDGNDIALTFTQLGSETNAFTTFDK
                     TSYFFSTVNEWQESLRLLQEFVAAPSFTEESVNREKHIITQEIEMYQDDPDYQAYSGI
                     LQNLFPNTSLAVDIAGTKESIRDITGSLLADSHAYFYHPSNMVLTIIGDIDIEEAFTA
                     IEAFQDSQPSQTQYDVQIAPLTYYPVIKSRSIDMDVATAKLAVGFRGQLMSSEYSLLT
                     YQVALRLLLAVLLGWTSKTYQDWYEKGKIDDSFDIEVDIQRDFQFVLISSDTSQPIAM
                     SNSIRKKISDFRCSRDVNEEHLELVKKEMYGDFMQSLDAIDQLASQFSLHLSEQETYF
                     DIPRIIETLALKDIIEIGSLFFEHAATSDFTVFPK"
     gene            complement(23223..24467)
                     /locus_tag="TVB59_001133"
     CDS             complement(23223..24467)
                     /locus_tag="TVB59_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEL1010034.1"
                     /translation="MKLIQGVQLHLIKNKTFKTNQITFRFSGDLNQKTVAKRVLVAQM
                     LATANDTYPTAKQFREKLAQMYGASLSTHVSTKGLVHIVDIDITFIQDQYAFYGEKLL
                     DEMIQFLKDILFSPLLSVAQYQPKLFDIEKRHLMTYVEADKEDSFYYSALKAKQLFYA
                     NDSLKLSKYGNTELIAKETAYTSYQEFHKMLNEDQIDIFILGDFDDYRMVQLLHQFPF
                     EGRRKKLDFFYLQQPVNVVNELVEQKQLNQSVLELAYHFPLVYGQAEYYALVVLNGLL
                     GAFTHSRFFTQIREKEGLAYSIGSRFDVYTGLFEAYAGIDRQHRTRALQLMVKELNDI
                     KMGRFSSSLVKKTKLMLKNNALLSEDNSKALIELEYMRSYIDPSYTLSSWLDEIDKVS
                     KLDIVRTANLLKLQAVYFLEGK"
     gene            24682..25095
                     /gene="yaaA"
                     /locus_tag="TVB59_001134"
     CDS             24682..25095
                     /gene="yaaA"
                     /locus_tag="TVB59_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEL1010035.1"
                     /translation="MTYTLFTDFITLQALLKEQGIIQSGGAIKGFLAQTEVFLNGQEE
                     QRRGKKLRVGDVITIPSQHIKIELVAPSQAEKTAYEAEKAEKERVAKMVKQMNQQAKK
                     AQTKQAATTKSKRGQATSAVKAKSNHQKPIRFPGL"
     gene            25097..26206
                     /gene="recF"
                     /locus_tag="TVB59_001135"
     CDS             25097..26206
                     /gene="recF"
                     /locus_tag="TVB59_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEL1010036.1"
                     /translation="MWIKELNLTHYRNYQQASAAFSPGLNVFIGDNAQGKTNFLEAIY
                     FLSVTRSHRTKSDKDLIYFDERDCSISGTLERLSGRVQLEILLSDKGRITKINTLKQA
                     KLSDYIGAMMVVLFAPEDLQLVKGSPNLRRKFMDIDLGQIKPVYLSDLSHYNHVLKQR
                     NAYLKSVHQLDNDFLSVLDEQLVTYGSRVMAHRLAFVQSLAKEANKHHQAISNGLEKL
                     SISYQASVSFEHQQEIYQQFMNQLKTTHQRDFLRKNTGVGPHRDDLVFYINDMNANFA
                     SQGQHRSLILSLKMAEVSLMKQLTGDNPILLLDDVMSELDNTRQTKLLGAVKKENVQT
                     FITTTSLEHLSQLPKDISLFKVNKGTIERDSIMID"
     gene            complement(26271..27134)
                     /locus_tag="TVB59_001136"
     CDS             complement(26271..27134)
                     /locus_tag="TVB59_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HEL1010037.1"
                     /translation="MEGILFALVPMFAWGSIGFVSNKIGGKPSQQTFGMTIGALLFAL
                     VVWLVVRPEMSMKLWIFGILGGIIWSVGQTGQFHAMQYMGVSVANPLSSGSQLVLGSL
                     IGVLVFHEWTKPIQFVVGTIALLLLIVGFYFSSKQDETNAASNQLHDFSKGFRALTYS
                     TTGYVMYAVLFNNIMKFDVLSVILPMAVGMVLGAAMFMSFKVSFDQYVIKNSVVGLLW
                     GVGNIFMLLAASKAGLAIAFSFSQLGAIISIVGGILFLGETKTKKEMRWVITGILCFI
                     VGAILLGIVKS"
     gene            complement(27305..29734)
                     /locus_tag="TVB59_001137"
     CDS             complement(27305..29734)
                     /locus_tag="TVB59_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEL1010038.1"
                     /translation="MMILTDEQRQRIAEEEYEKHTVGSPVLIDDDNSEFSIGYVSQIE
                     DSISGFQAYVVTDVKLPPHPTKADYAQVKHVTMLYRGSTGPDQWQKHPVDVVADWVGN
                     DLPMAMRILLPDQTPTKGTAQLRKAATFTNKTLKQYPNATFEFYGHSLGSMTVQYGVT
                     SVSDKNLSRISGVYIYNGPNTYRVLNEYQRKRAKLLHDRIYNYVDPHDIIGMGFDQKE
                     GAVGQVFVVNTKKVNDIVLQHMWHGYQYDQYGNMTDVNGRFVHANVLLPIDIDSDNRL
                     DTKVEELYLGFRNYFDSSTSARYGVLSDKQTIVINAGVLTNLAQNLQSSISGDLQTIR
                     HITEKCQAKNDAIKDSFEERKKRVSENIKALLATNGLTDTFNSLQSSLERLVGQQDLF
                     DMLSHSASLDYPFSYDEIPYVNNNRLNLAMYDSELASLNTKSLQLASSAQHEKSGWID
                     SIIGRSTLLKSWQIIDEASRQLLKESDKTFEGTGLRESKVDGISDSLKEVFSVELQDI
                     IELEKMIINTSELILGVSQNVTATDNWLGNSLKNGQFQGSADVVCVPSSYDAYLERTG
                     LLDDVRDILQAFDEQVEQKSRDYSRKVASVYASTFSRLFDTLDYWTTEVNIFKNIVTV
                     LERRFSDRVYVERTEIKDETSTTTRSYWGNLGALYPCRIRSGIASARAEVCPLVPALT
                     DTIQRVNTARHRLQNLHGDLSRLIEKGVYSALDLDDIITSQKMVGRLLDKIIVELSFV
                     KATIEASMSGQAASAMVNHLALLLKRLGYFSQLVADCFGTQVTKVPNKAPARASHKVK
                     RFSLNNPLALQ"
     gene            29956..30039
                     /locus_tag="TVB59_001138"
                     /pseudo
     CDS             29956..30039
                     /locus_tag="TVB59_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002932394.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            30067..>30235
                     /locus_tag="TVB59_001139"
     CDS             30067..>30235
                     /locus_tag="TVB59_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEL1010039.1"
                     /translation="MIRLIDRYGLAIVQKGKNSYYSPELKQEIIDKVLIDGQSQKQTS
                     LDYALPNSSMLS"
BASE COUNT         9305 a         6590 c         5545 g         8795 t
ORIGIN      
        1 tgagagatat gttggcttct gatttcatat aagacctgcc atcgcccttc ctgccaaatc
       61 aaaggtaagc aaaccgcata acatcgctcc tcacccaagg gcctagcctg ataatgttca
      121 ataatgctct tcatctgtcc ttctccttat catatccatc actaagctac tttcatagta
      181 taaaatagta atcctttggt caagaaatgg ctccgattac tctctatgat atataaaatt
      241 tttatatata aaatattgac atattaaaac agaaactcta tacttaatat ataaaataat
      301 tatatataaa tacgaggcag gaagggagta accagatgta ttttccagta tctgctacct
      361 tgattgaatt tttgatttta tctattgtcg acaagcatga ttcctatggt tatgatatca
      421 gccaaaccat taagcttgtc gctaatatca gggaatcaac cctataccct attttaaaaa
      481 agctagagaa atcagactat ttaactacct atagtcagga acatcaaggt cgcaagcgta
      541 actattacac cattacagcc aaaggcgaaa agcagctgat tttcttaaag gaagaatggc
      601 aaagctacaa ggccacccta gatggcatta ttgaagggag attaaggcat gacaagagat
      661 gaatacctag cagagctaga caaataccta cgaaaattac ctaaagcaga ttattatgaa
      721 gctgctgaga actcaagtca gctagaactt aacgacggca gtatcaaaga ctcttctatc
      781 actgtagctg atacaaaaga agaaaacgac tatgactata cagacccctc cgagcttgct
      841 ataaatcatg tcacaatcaa ggagaaaaac acaattaatg gcggcgatat taatatcaat
      901 accacattag caaatccaag agatattgct tatcatgtca caacaagagg caacatcaag
      961 ctcagctctc gtttttcaaa cgccaagctt aacacagacg cagcaacagg agctacttca
     1021 tttcactctg acatagccaa tactgtcaat caaagcgacc tatcaattca ttaatcaagg
     1081 gaggatatca taatgactaa acaagatttt ctagacaagc taaagcagca gatcaaccat
     1141 ttacctcaaa aggattacca agaaatcatt gaccatttta cagagtattt tgacgaggct
     1201 ggtcctgacc atgaacaagc tattcttaaa gaactgggaa atccagagga cattgccaag
     1261 gagctattaa aagccttaga tctccccgaa aaaacagacg aagatgactg gacgaattgg
     1321 gaagttgaca acaaaacaaa gtcagaagca agctcacaaa agcttgagcc aatagttgac
     1381 attcgctata gtctgcttaa ccatgattta accattgaaa ctgctgacat tccttaccct
     1441 actatttcat acgatgataa tcgcatcaca ataagccaag atagtgacgg catgctcaat
     1501 atcattgaag actcagcagt acaaacaata cagtatggct ttcatttcct agaccgctgg
     1561 cttgcaaaat atcaacccat taccttgaca ctacctgtca accaccacct gaaaaaaatc
     1621 tctggagaaa gtgacaacaa cgatgtcacc ataaggcata tacattgtga tagcattgtc
     1681 tctaacactt acaatggaac gatttctatc agtcatttat cagatagcac tgtcaaccta
     1741 agcagcaaaa atgggaacat tattttagag cattgcaata tccagtctag taaatgtcaa
     1801 gccaaaaatg ctaacctcag ctgtgacaat agcaccctaa taaattgcca gctgaacaat
     1861 aacaatggaa acatcagatt agaagcaagt cagctaacag aaaccttcat tgaaaacaaa
     1921 aacggtaata tcatagggca gcagctgtcc ttttccaatg acatcactat catcaataag
     1981 aatggaatca ttgacatcaa ttgtcctaga gaaaacctca tctactatga cgtaaaggct
     2041 tcaaataata atggatttgt aacgattagt caagaagcag gtcgtcaaac accctttaaa
     2101 gcacagctta ccatttccaa taataatggt cttatctccg taagctaaac caaccataaa
     2161 aaaagcttct agaaagagct taaaccacaa tttctagaag cttttttatt atatctactg
     2221 tttaacgata acctgttatc tcagctatta tctaggacga ttgcttgtcc tttggacgat
     2281 aaatcagcac tcctatagcc ataaagctta acaaaaagcc aactaataca ctcgtctcta
     2341 aacctatctg ggcagttaat gatattgtct gacgaaggcc agagacaata taagacattg
     2401 gaagataagg atggagaatc tggaagatct gaccactcaa ctcaatagga taagaaccac
     2461 ccgcagcacc aacctgtagc aacagcataa ttaacgaagc aaaggcacca tatcgagcat
     2521 cccagctgac caatgcagtc actaaagcca tcaaggccca tccactcagc ataataaagc
     2581 ctaaggtctt gataccgtca ttagcttcaa agcccagcag ttgaagtgca gcgtaaagaa
     2641 taacagagcc aacggtcgaa atcatgccat tgatcagtaa tttttgcttt gcccaatccc
     2701 atctatcttt aatcggctta ccagataagg cctctgcaaa aataatattt gtagacaagg
     2761 caactaccat tagagacaca gcaatcatat aaggagccat gccaatacca ttggtcctaa
     2821 ccttatcctt gtccttctct gataacgcta ctggatcaga taccatatca gcattctggt
     2881 cctctaccca agccattgaa agctggtcag aagcttttga tagtgaggtc gttaagcttg
     2941 acagacctgt tgacagagtt gtcaagccat ctgtcaactg agagctgcca gaggagagct
     3001 gattggctcc aaaagctagc tgattagcgc ctactgtaag ctgctgtcca cctgctaata
     3061 attgactgga ttgatggtta agagctgttg cccctgtagc aagagtagac aggcctgctg
     3121 taagagcttc attcttagct gtcaattgat taaagccgcc agcaagagct tgactacctg
     3181 ataagagctg ggctgttgtc gctgagtgaa cagcccttaa accagttgaa agctctgaca
     3241 atgccttgcc tgtgctaggt aggatttgat cagcttgata agccagctga ttaacaagtg
     3301 ctttaaagtc cctcagttga tcagctacac cagcacttgt tgacatagcc tctagctcct
     3361 cagacatggc ttgcagtgat gtcaacatag cctttgctga tattgttact ttagttgaag
     3421 tattggaaat agctgagctc agctcctcct gctgctcaga gttgagacct tgataggtag
     3481 ctgtagcttg tagagcggct agctgattgt tcttgtcagc agtatcatct accacaagct
     3541 cctgcactaa acgcgtcata tcggctaaat gcttagcaat ggctcctgag tccacatttg
     3601 gtgccaaaga caaggaaaga ttggtcttta gctgctggat agcctgatta agctttggta
     3661 ggctagccat taaagcttga atattagctt gtttgtcttg agacagatca cttcctagag
     3721 ccaattgggt caagccagca tttaactgat tagcaccctt ggataaccga gaaacaccat
     3781 ctagatacgc tggcatatca gctgctagct gtcctaagcc cgcggtatca agctgaccaa
     3841 caccggctgt ataggcagct ataccactag atagattacc cgctccttga gacaagcgag
     3901 cacttgattc agacaaggtg ttcaaatgcc ttgacattag ctgactgctt gccctagcaa
     3961 ttactaagcc agcggctaat tgctgaccgc catttgaagc ttcctttaga ccagattgga
     4021 gctgatgcat gctcttaaaa acggaggtga tataggtctt ccttatattt ttagaaacag
     4081 cctctctcaa gtgattcata gcagattcac ccattttaga agcgataaag ctatggccct
     4141 tactagtttg atagctaaca atcagcttct ctggctgctg atctaatagc gtagtggcct
     4201 tttgtgacaa atcctttggc aacgtaatcg tcatataata acgacccttt tccaagccct
     4261 tttgtgcggt atctgcagcc acaaaatgat aatccaattc cttattttta gacatattgt
     4321 ctaccatatc gttaccaata gtcagtctct tgttattcaa gtaagcaggc ttatcctgat
     4381 tcacaactgc tacaggcaac tgatcaaccc gaccataagg atcccacatg gaccctaaaa
     4441 aggacaaatt atagagagct ggtactagag caaccccaat cattgtcact actagcttac
     4501 gatttttgat tattgctttt aatccttcta gcattatttt ttctccaaat agacatactg
     4561 ttcaaaaatt atgataaaat atattataca aataaagtga cattttacaa ggaaaaaata
     4621 aattttttag acataatgtc tacaagtgtt caaaaggaga taatgatgga tagccgcaag
     4681 cagcaaacca agaaggccat tcttaatgca atggtgagct tactaaaaac cgaaagcttc
     4741 gatgatgtaa caaccgttca gcttgctaaa atggcaggca ttagtcgttc tagcttttat
     4801 actcactata aagacaaata tgagatgatt gattactatc aacaaacctt ttttcacaaa
     4861 ttagaataca tttttgaaaa agaataccaa aacaaggagc atgctttttt agaagtattt
     4921 gaatttctca agcgagagca actactatct gctctgctat cctccaatgg tacccgagaa
     4981 atccaaagct ttatcattaa caaggttcgt ctgttgatca ctaccgatct tcaggacaag
     5041 ttcagtaagg acatcttgtc cccaaccgaa aaggaatatc gaagcatcta cctagcacat
     5101 gcctttttcg gtgtctgcca aagctggatt gctaaaggaa aaaaagaatc ccctcaggaa
     5161 atgactcgtt tcgtcttaaa aatgctatct aaaacatagt cctgcactaa tgatgtcaaa
     5221 tccagtacca aaaaacaact ttgtaaacta tttcttactg agtttataat gatctttatg
     5281 cctaacaata ccgacctcca atcgttagac ttttggtcta acctttgggg tcggtacata
     5341 aatcagctaa ccgctcaacc aaaaaagccc actgttgtgg gcttcttata atataaagtc
     5401 ttatcttaaa gcattttgtt gtagaattca acgacaagtg cttcattgat ttctgggtta
     5461 atttcgtcgc gctctgggag gcgagttaat gatccttcaa gcttttcagc gtcaaatgaa
     5521 acaaaagctg gacgtccaag agttgcttca actgcctcaa ggattgcagg aaccttcatt
     5581 gatttttcac gaacagagat gacttggcca atctcaacgc ggaatgatgg gatatcaaca
     5641 cgcttaccat caacaagaat atgaccatgg ttaacaaact gacgtgcttg acgacgagta
     5701 gttgcaagac ctaagcggta aaccacattg tcaagacgac gctctaaaag aagcatgaag
     5761 ttgaaaccaa gagttccttc tttgattttt gtagcttgta cgaataggtt acggaattgt
     5821 ttttccccca taccatatga aaagcgaagc ttttgcttct cagcaagttg caagccatat
     5881 tctgaaagct tgctacggtt gttagggcca tgctgaccag gtacgtagtt acgacgtgcc
     5941 aattccttac ctgtgcctgt caatgacaag ccaagacgac gtgattgttt ccatgatgga
     6001 ccagtataac gtgacatgta tcatgtcctc ctctaaaaaa tataacgagg aaataactgt
     6061 ttgaaaaatc ctgattcgtg caggaggttt tcgcctaaac agcaaaggtt actcaattta
     6121 gttaaccgcc tgttgacgag cttcatattt ttctgctgtt atttcacaca aaactaattg
     6181 taacatgaaa aaggtattga ttcaagtttt ttttacattt ttaatatcat atcatcaaaa
     6241 atggttagct gtaagctcaa agatgatgtt aatcatatgg caaacaagct tttacacaac
     6301 acttcccgag taaacaaggc tttttaatac cgataggaaa ttctttgaaa atagcatatt
     6361 atgttttgat atctaatacc gagagtctca gagtaactgc ttttcaagaa agctagtccc
     6421 tattattagt ccgggcttca ttcatttgct aataagttct tcaaggcttc aaattgattc
     6481 atatctttac acagctgtca acaaagtgta aagaaaaagc cctaaatggg cattgatttt
     6541 tcaatcaaaa taacgaatca gtgttttttc cgtcaaaata tctgaatagg tataagactc
     6601 aacataagaa ttattcgctt cccctgaagc atctgggttc ccctgatact caatgataaa
     6661 taaagaaggg taaacctcta tcaatctgcc aaccttattt ttttcacgct tacgaccatt
     6721 ttcaagtgtt aactcaacca actgaccttc atgagcctta atgtcttcct ttattttttt
     6781 cattttggca acatctgtaa atgcatcact cattctcttt ccctctttct tatctttcct
     6841 caaattgagc tattgtcgaa aatttattgt attccttttg aaacatcagc ttaactgtcc
     6901 cacgcgcacc tgccctattt ttctcaagaa tcacctcaat tgtattatcc tcaagagcct
     6961 cttctgtgct gtcgctttct ttacgataat aatcatctcg gtacaaaaat gcaacaatat
     7021 ccgcatcctg ctcgatagag ccagactcac gaatatcaga caaaactgga cgcttgtcct
     7081 gcctctgctc aacaccacga gaaagctgac tcaaagcaat aacaggcact tttaattcct
     7141 tagctaaaat ctttagctgc cttgaaatat cagaaacctc ttgctgacga ttttcaggtc
     7201 ttgtaccagt gatcagttgg aggtaatcaa tgacaattag ccctaagcct ccctcaacct
     7261 cctgagacaa tttacgtgcc cttgctctga tctcagtaat cttaatgcca ggtgtatcat
     7321 caatatagat aggtgcttct gccaaggctc cttgggcaat ggtcacatta ttccagtcct
     7381 gatcagtcaa ctgaccagtc ctcaagctat gtgaattgac cattccctca gcggccagca
     7441 tacgatcaac aaggctttca gctcccattt ctaaggagaa aatggcaact gctctctttt
     7501 gctttgtacc aacattttga gcaatgttta agacaaaggc tgtcttaccg actgcaggac
     7561 gagctgctaa aataatcagt tgatctgggt gtaaacctgt tgtaatcttg tcaagatccc
     7621 taaagcccgt tggtaaacct gtaacgtctg atgtctgctt agaacgaacc tcaagatttt
     7681 cataattaat ctttaaaacg tctgagatct tacgaaagcc actgcgattg ctatgctcac
     7741 tgatatcaac caaggccttc tcagcacttg caataatatc ctccgagtca gatgctcctt
     7801 cataggctaa gtttacagtc tctgtcaacc tattgatgat atcgcgtagc atagcctttt
     7861 cagctactat tttagcatag tattctgcat tggcactggt aggtacacta ttaaccagct
     7921 caacaatata agacaagcca ccaatatgtt gaaggtcccc ttgatcatca agaatcgtcc
     7981 ttaccgttgt tgcatcaata gcatcatttc gatcactaag ccttatcatt gccctgaaaa
     8041 tgaccttatg agaatactta taaaaatcct ctggaccgat aaattctcta acggtaatca
     8101 acttgtctgg ggaaataaag atagagccta gtacagactg ctctgccaat aaatcttggg
     8161 gttgaactcg taactcagca acttcaggca aactcagcac ctccaaatct tttttaggct
     8221 gatgtgctat gcctcagcaa tgtttagttt tatttcagct gtcacttctt tatgcagctt
     8281 aactggcact tcgataagac caatagcacg aatagggtga tctaaaacaa tatgacgctt
     8341 gtcaaccttg accttaaatt gcttttgcaa ttcctcggaa attttcttag ctgtaattga
     8401 gccaaaggta cgcccatctg gtccaacctt ttccttaaac tggacacgag ttttttcgtc
     8461 atctaagatt ttcttaacag ccttagcctc tgctaggatt tcagcctggg ctttttcctc
     8521 agctttttgc tgccctctta gctggccaat tgcttgactg ctagcttcct ttgctaaatt
     8581 tttcttaatc agaaaattct gagcataacc agtgggaacc tccttgattt ctcctttttt
     8641 tccttttcct ttaacgtcaa ctaaaaaaat gactttcatg actctacctc tcttgtttct
     8701 ttcattgtgt tatcaattgt ttctagtaac agctgcttag cctcgctaag actgatatgc
     8761 ttcatctgac acgctgctaa gttgaaatgt cctccgccgc caagcttttc catcattctt
     8821 tggacattga tcttactacg acttcttgct gatatagcaa tcttatcagc tcctgtctct
     8881 acaataacaa agctagcctc aatatgggcc attgatagta tggtatctgc tgccttacta
     8941 gcaatgacat tactataata ttgcccagca agcccagttg caacgataat ggagtcgcta
     9001 aggcgctcac ctctgagaat gatctcatta acctgcttat agtcatcaaa atcagttgct
     9061 gaaatatttt gaatttcgac gctatcacta cctctgcttc gtaaataact ggcaacatca
     9121 aaggttctac tggtgacacg tgttgaaaaa ttcttagtat ccagcataat accagccatc
     9181 aaaacacttg cttgaatctt gtttaagcgc ttcttcgcat tttgaaactg gattaattct
     9241 gtcactagct ctgcggcact gcttgcacca ctttcaataa aggtcaagat agcattatct
     9301 ggaaaatcat catctcttcg gtgatgatca acgacaataa catcttgaaa ttgctcgtaa
     9361 aattccttag acaaggttaa ggaaatctta gagtggtcca ccattactaa cagtgatcta
     9421 ggggtcgtaa gccccattgc ttgagaaata ctgataagac gtgtcttacc atcagcctgt
     9481 aagcgctcaa tagctctttc aatgtctgga ctcatctcat ccggattata gacagcaaag
     9541 ctgttttcaa taatgttact agcaaaaaat tgcatgccaa cagccgagcc taaggcgtcc
     9601 atgtccagtt tacggtgacc tacgataaac acattatcaa ccattttgat acggtctgaa
     9661 atagctgtca tcatggcacg cgtcctagtt ctagagcgtt taaccgtaga aacagagccg
     9721 ccaccaaaat agaccggatt tgtatggtct gcattttcac gaataacaat ctgatctccg
     9781 cctcggacaa gagcaatatt cagattctca agagcaacct gaccaatttg acaatgattt
     9841 tcctctccaa aggaaatgcc catacttagg gtcaatggta gctgcgcttc ttgggcttcc
     9901 tttcggaact gctctaaaat agaaaactta tcgtccatca gcccttttaa gatcttatag
     9961 tctgtaaaaa agtaaaaacg atccatatta acacgtcgat aaaatacctg cttagactcc
    10021 ataaactcag ctatgaaatt agccacaaat gaatttatct ttgacgtatc agcatcagat
    10081 aagtcatctg taatgtcgtc ataattatcc acagaaataa taccaataac tggctttagc
    10141 aagctagaat ctgctgattg tctactacca acagagctat caaaaaagta aaaaatacct
    10201 gatgccacat caatataaga cgtgtatcga ttgccagaaa cctcaaaggt ttgagaaata
    10261 tcacttttac gcttatcagt gagaagctgt tggatcatct gttcctgtaa aaaaccggcc
    10321 tcatcagtga aaatcagctc tgcgtaagga ttgtaccatt caatagcatt ggtttcttga
    10381 tcaaactgaa taacaccaac tggcatgtta tccagtaatg tttttaaatt attttctgtt
    10441 tgttcgttca atagctcaat gtggtctaaa tcagacaatt cgtaaacctt tttttgatac
    10501 caaagcaagg ccgcaacaaa caacaacact aaaaaaatag ctagtgtaat cagcattttt
    10561 gattgcatga ttctaacaca taaggctagt aagccgaata aaatcaactc catcataatt
    10621 aaatgaatgg tttcaaaacg aaatcttttc atctttaacc tcttaatccc gtattatacc
    10681 ataaaacagc cctgaaatac agagctgtca gtggttttga gattacaatt tgatgactat
    10741 tatgttttac ggcgagcctt tccattacct tcaaggtaaa ccattaaaat gctaatatct
    10801 gccggattta cacctgaaat gcgactagcc tgaccaatgg tttctggatt gattttctta
    10861 aatttttgcc ttgcctcagt agcaattgag tcaatagcgt cccaatcaat ggtcttagga
    10921 atccgctttt cctccatacg cttcatttta gcaacctgat caagggcctt tttgatatag
    10981 ccttcgtatt tgatctcagt ttctagtagc tcaatcagct tagcatctaa tccctcagca
    11041 gcaggaccta taaatgacac tacagtggca tagtcaacct ctggtcgacg cataaattcc
    11101 ttagctgtca ttgcgtccgt caaggactta aagccaagct tttgaacacg agcattggtt
    11161 tctttgattg gctttaattt gatactatct agcctcttta attcattgtc aaattgattt
    11221 ttcttgattt caaaggcaga ccaacgctca tcgtcaacca agccaatctg acgaccaatt
    11281 tcagtcaatc gcatgtccgc attatcatga cgaaggataa gacgatattc tgcgcgtgat
    11341 gtcagcaaac ggtaaggctc caaggttcct ttggttacca aatcatcaat cattacacca
    11401 atataagcgt cgctgcgctt taaaatgagc tcaggcttac cctgaacctt caaagcagca
    11461 ttgataccag cgacaaggcc ttgaccagca gcttcctcat agcctgaggt tccattggtt
    11521 tgcccagctg taaaaagccc tgaaatcatc tttgtttcaa gggtagcacg aagctgatga
    11581 ggtaatacaa tgtcatactc aatagcatag cctgttctca tcatctcagc attttcaagc
    11641 cccttaatag agtgaaccaa ttccttttgg acgtcctcag gaagacttgt ggatagacct
    11701 tgaacataga cctcctcagt gtcaaagcct tctggttcta aaaagagctg atgacgctct
    11761 ttatcagcaa atcgtacaat cttatcctca attgatggac aatagcgtgg gcccactccc
    11821 ttgacgactc ctgaaaacat aggtgctcga tataggtttt tagtgatgat atcatgacta
    11881 atctgattag tgtaggtcag ccagcaagga atctgattag ccaaataatc tttgtcctta
    11941 gacataaagg aaaaatgatt tggagtcaca tcaccaggct gaatctctgt cacctcataa
    12001 tcaatagaag aagccttgac acgtggtggg gttcctgtct taaagcggcc aatttcaaga
    12061 ccaagctttt tcaaattatc agctagtgtc actgaggcca agctgttatt cgggccagac
    12121 gaatatttca attctccaag gataatctca ccacgaagag ctgtacctgt tgttatgatc
    12181 actgcctgag ctgcatattt ttgccctgtt gctgtcagca ctccaacaac cctaccattt
    12241 tctactaaaa tatcatcaat catagactgg cgaagagtga ggttttcttg cttttcaaca
    12301 gtatgcttca tctcacgtgc atacaagctt ttatctgctt gagctcgtaa tgctcgaact
    12361 gccggtccct tacctgtatt gagcattttc atttggatat aggttttgtc aatgtttttc
    12421 cccatctctc caccaagagc atcaatttcg cgaacaacaa tacccttagc tgaccctcca
    12481 atagagggat tgcatggcat aaaagccagc atatcaagat ttatcgttgc taataaggtt
    12541 ttacacccca tacggctagc cgctaagctg gcttcaacac ctgcatgtcc tgctcctaca
    12601 acgatgacat cgtaggattc tgtaaattca tgtaccatat ctactccttt atctcaatat
    12661 gttttatatg ctgaggctgc ctgtcccaat gctttatagc cctttttaaa caactaggat
    12721 tgagccttat cttatctaga tcatcaagag caacccactc acaaacccta gtacaatcac
    12781 cctcaactac agaagggcta gaatcagata atagactcac aatataatga aactcaatct
    12841 gatgaaagtt cactccttct agacaaaatt gattttcaac cacaaaggct aactgagcaa
    12901 ctgaaacctc agctcctacc tcctctagaa cctcacgctt gacagcttct tctgtgcttt
    12961 ctccaacatg aatagcacca cctaaaagat aatagtcctc tttgggtgat ttggcaagat
    13021 aaatatagcc atccttaatt attaacgctg aagccctaac accaaagcta tggtctgcta
    13081 tccttgttct aaaatcctga accatctttt ctccttgaca ctgtttttaa gctataaaaa
    13141 tagtcaaaac ctgagaaagc tgtaagccaa aaagacttac aattcccatg agctttgacc
    13201 atcatcgtta ttgttaacct tattctatca aaatctgcca gcttgtcaag acttatcaga
    13261 tgacaaaacc gtcaacttta ttgacacatc tgtcaattaa catgtcaagc taaatatatt
    13321 gacaaggctc gccatcttta tacgccatat caataatacc accaccaaga cactcatgac
    13381 catcataaaa aacgactgct tgaccaggtg taatcgcacg ctgaggctca gcaaaaacaa
    13441 ccttagcttt gtctttcttg acatgaaccg tcaccttaga atctggctga cgatagcgga
    13501 actttgctgt gcattctaag gtgaattctt caggaacttc tcttgtaaac tgaatgacag
    13561 aagcgtcaag actagttgac attaaggact cgtggtaaaa gccttgacca acataaagga
    13621 tattttgtga aaggtctttt ccaacaacaa accaaggctt gttatctcca ccctgctgac
    13681 caccaatgcc aagtccccca cgttggccaa tagtataata catcaagcct gcatgctctc
    13741 ccatatcacg accatcaaca gtcatcatac gccccttttg agctggtaaa taatggctaa
    13801 gaaaggtctt aaaattcttc tcactaataa aacaaatccc tgttgagtct tttttctttg
    13861 ctgttgcaag gcctgcttgt tcagcaatag cacgtacctc tgatttttgc aggtgcccca
    13921 agggaaacat ggttttttgg agttgctctt gtgatagttg gcttaaaaaa taggtttgat
    13981 ccttaccctt atcaagacca cgcagcatat ggactacacc attctcatca cgtttgattt
    14041 gggcatagtg acctgttgcc acataatcag cacccaatgt catcgcataa tcaagaaagg
    14101 ctttaaactt tatctcctta ttgcacatga catcaggatt tggggtgcgt cctgaacggt
    14161 attctgctag gaaatactca aacactctat cccaatactc tttttcaaaa ttaacagaat
    14221 agtaaggaat accaatctga tcggctacgg ctgccacatc tttataatcc tcagtcgccg
    14281 tacaaacacc aaattcatct gtatcgtccc aattcttcat aaagacgcca atcacatcat
    14341 atccctgctc ctttaacagc aaggcagtta cagatgaatc aacaccgcca ctcatgccaa
    14401 caacaacacg tgttttcgag ttatctgtca tcatttattc tcccatcaat ataagataca
    14461 aggacatgag aaaaagaata gaacgaatca acttgcctaa acaagactct agcaaatggt
    14521 tcatttctat attttttgtc tttgtccaag tgttttctca aagctcgatt tgaaggtcga
    14581 tttgaagcgc cgctagacgc atgactatta taacagtatt gtctcttatt tccaacaata
    14641 tcttttttca taacaaacga catttgatta gcgatttgtt ataataaaaa ggataaaaag
    14701 agcatggagc atatatgaac acacaaaaat ttcaatcagt ttttgacatc attggaccag
    14761 tgatgattgg accatcgagc agtcataccg ctggtgctgt tagaatcgga aaggttgtcc
    14821 actccatttt tggagaaatt cctgatgagg tgacctttca tctatacaat tcatttgcta
    14881 agacctatca aggccatggt accgacaagg cactagtagc tggtattatg ggcatggata
    14941 cggataatcc aaacatcaag aattctcttg aaattgctca tcaaaagggc attaaaattt
    15001 attgggatat tttaaaggat agcaatgctc cccaccccaa tactgtaaag attagtgtca
    15061 aaaaggctga taaagcaatg agcattacag gtgtgtcaat tggaggagga aacattcagg
    15121 tcacagagct aaatggtttt tctgtttcct tgtctatgaa tactccaacc ttgattattg
    15181 tccatcaaga tatccccgga atgattgcta aggttacaga tatattgtca gctagtgata
    15241 ttaatatcgc tcaaatgact gtgactcgtg aaagtgcagg tgagaaagcc attatgatta
    15301 ttgaggttga ttctcgtgat tgtcaagttg ctgtcaagca gattgcaact attcctaatc
    15361 tgcataatgt caatttcttt gactagaaag gtatattatg ttttacacaa ttgaagagct
    15421 tgtcaagcag gctgatgata ggtttgatgg taatgtagca gagctgatga ttgctacaga
    15481 ggttgaaatg actggtcgaa gcagggcaga aatcctatcc atcatgtcac agcatttaca
    15541 ggtaatgaag gattctgttg tcagcggatt gacagcaacc aaatctatta gcggattgac
    15601 tggcggtgat gctcttaaga tggatcatta catcaaaaaa ggaaaggggc tttcagatca
    15661 aaccatttta acagctgtga gaaatgctat ggctgtcaat gagctaaatg caaaaatggg
    15721 acttgtttgt gcaaccccga ctgctggaag tgcaggctgt ctacctgctg tccttgctgt
    15781 tgctattgat aagctcaagc tatcagaaaa ggaacagctg gactttctct ttacagcagg
    15841 tgcctttggc ttagtcattg gaaataatgc ctctatctcc ggagcagaag gaggctgtca
    15901 agccgaggtg ggctctgcct ctgcaatgag tgctgcagcc cttgttaagg cagcaggtgg
    15961 taccgcttat caggctagcc aagcggtagc ctttgtgatc aaaaatctat tgggattggt
    16021 ttgtgatcct gttgctggct tagtcgaagt tccctgtgtt aagcgtaatg cattaggatc
    16081 aagctttgct cttgttgctg ctgatatggc attagcgaat attcagtcac aaattcctgt
    16141 agatgaggtt gttgatgcta tgtatcaggt tggtgccgca atgccaacag cctttaagga
    16201 gacagctgag ggaggattag cagcaacccc aacaggtaga cggtatagta aagaaatttt
    16261 cggagactaa tataatcaag taacgataga ctgaggagac gtcatgaaag caatcctatt
    16321 tgacttagat ggtactttgg tggattctag tataggaata ctaaatgcct ttgaatacac
    16381 ctttcaaaaa atgaaaatcc cttgtcctga tcatagcata ttatcgtctt acatcggacc
    16441 acccttagaa gcgacctttt cagcattttt taggaatcag catgatgtcg aggttgctat
    16501 aacacacttt agagattttt acagggaatt aggcatttac caagcaaggc tttattctgg
    16561 aatcacagag ctattagata atctctcgca agaaggtctt gacctctatg tgacaactag
    16621 taaatatgaa cctatggcaa ggcaaatgct tcaggattta acgattagcc attatttcaa
    16681 agctatccta ggctctattt ctaatcggtg tcacaagttg gatatcgtca aggcatgctt
    16741 acaagatttt gctattaata aaaaagaagc tataattgtt ggagatacca aatttgacat
    16801 gattggtggt aaacaagcag gcattacaag acttggagtt acttggggat ttggttgtca
    16861 agaggattta caagcacatg gcgcacaata cattggacac acaccccaag aggtgattga
    16921 gattatccag tcattgtaaa acgatactaa aaacctatca tcacacaaga tgataggttt
    16981 ttaacgctgt tatctgttct tagtagcccc aagctgataa gccctgtgca cgataggcat
    17041 ttaaggctga atttacctga tcctgaacgg ttgcagttga tccccagcct ggcatggttt
    17101 ggaataatcc tgaagcacct gaaggattag ctgcgttagg gtttccattt gactcacgag
    17161 cgataatggc ttcccaagta gcttgtggaa caccagtagc tgccgccatt tgagctgctg
    17221 cttcactacc gatagcccct gcggtattgc cgttagaaag gattactcca ttgctataag
    17281 ccactggtgt agctgcatac tgagcttgag gagcagcctc ttgcacagca ggactagcta
    17341 cctcagaagc tactgattcc tgagctggtg ctgcatcagc agaggaaggc tctgcctgct
    17401 cagctggctg ctccttggtt gcagcctttg ctactgttga tttttttgtt ttatgatgtt
    17461 tcttcacaac cttagtatca gaagctttag cataggaatc agtgtttaca ttttcacttg
    17521 aaaaagcaaa aactactgcg agcaaagcaa tagcagctgc tacaatgcca aaactaaaat
    17581 aacgttgttt caaaatgtct tgtttaaaca ttaaataaat acctcacttt tctctgttat
    17641 ccatattaac tgttaattat tacttgtcta tttaagatat attaaaaata ttacagcaat
    17701 attgatattc caagttttct agcctgatat cagtgttttt tgagcttaag aagctcaaaa
    17761 taaaaacaat gcctaagttc agacctgtgt aacagatgat ttaagcattg ttattattaa
    17821 taaattctag ttgctacagc ctaacaaagg ggctgctgta atatagctag gtgagccttg
    17881 agggactttt tagacagaaa aggaaaatcc ccaaaatgac taccaaaata atggctagag
    17941 tgtcttttaa ttgccagctt agcaggcggt attttgttcg actgtcaccg ccttgatagc
    18001 ctctagcctc catagcgatc gctaaagcgt cagctctttt aaagcttgaa gcaaaaagag
    18061 gaatcaaaat agggataatc gactttacct tttgaataag attgccttct ccaaaatcaa
    18121 cacctcgcgc tttttgcgca ttcataatac gagttgtatc gtccatcaag gttggaacaa
    18181 accgtaagct caaagataac atcaaaccga tctcatgggc aggtacctta aacctaacta
    18241 aaggcttcaa cagcgcttca acagcatcag ataagcttag tggggtggtg gttagggtta
    18301 acagcgtgga aaagaaaata atcaaaacaa atcgcatgaa aatcaaaatg gcttgactta
    18361 atcccaagct tgttatctta attattccaa gctgaaaaag aactgatcct ccctgtgtaa
    18421 aaaaaacttg aaaaagcgtt gtaaatagga taataccaat cataggctta acaccattga
    18481 aaaagaaaga ccattttatc tgtgacaaga aaatcagcag caaggtaaat gctaacagca
    18541 aaagattagt taccacatta ttggcccaaa aaataatgat aatatagata atcatagcaa
    18601 gcagcttgct tcttggatca agccgatgaa taattgaatt cccaggaata tagcgaccaa
    18661 gaatgagttt atccatgctt taatacctct cttaattcct ccaaagtaat gggtaaatag
    18721 ggtaaatcaa agccttgctt agccaggcgt tgggcaaagg ctgtcacctt agggacacct
    18781 aattgttttt cttttagcaa atcaatgtgt tgaaaaatag cctttggctg acctgataag
    18841 atgattttac cagcttcaag gacataaaca aaatcagcat aattagcaac atcgtccatc
    18901 agatgtgtca ccagtacaat ggtcatgcct gattgatgga gcgatttaaa aagactcatt
    18961 aattcctttc gccctttggg atcaagccca gcagtaggct catctaacac caaaatatcc
    19021 ggctgcatcg caagaatacc cgcaatagca accctgcgca tctgcccacc agaaagctca
    19081 aatggatttt taccaaatag ttcctctgaa atccctacta gggttaattt ttcacgcgct
    19141 aaagcttccg cctctttctg agaaacacca aaattttgtg gtccaaaggc aacatccttc
    19201 aaaaccgttt cctcaaaaag ctggctctca ggaaattgaa agactagacc aacctgctta
    19261 cgaataggct taatatcttt attttttgac tgactagtta tctccttgcc tgctaccgta
    19321 accttgccgg tggtcggcag atgcaagcca tttaagagct gcataatcgt tgacttgcct
    19381 gagccagtat gaccaataaa agccgtataa gagccgtcta caatatcaag attaacgtca
    19441 aaaagggcac gcccctcaaa gggtgtccct gcttgatacg tgtagcttac attttggaaa
    19501 tgaattgaca tagctgttcc tctaattcct tttctgtgag atagattccc tgtatagggt
    19561 agccgtcttt ttttagcata ttaacaacag aggttgtaaa aggaatatct aaacctagat
    19621 tgatcaattg attgccccta gcaaatagct cctgtggagt cgagacagac tcaacacgcc
    19681 cattgttcat caccaaagct cgatcactaa gagccacctc atcaagatca tgtgtaatag
    19741 atataacagt tagttggtat tcttgtctaa tagattgaat tgtccgaatc aactccagac
    19801 gcccctttgg atccagcata ctggttgctt catctaaaat gatgatcatt ggccgcatgg
    19861 caacagcacc tgcaatagca acccgctgct tttgaccacc tgataatctg gaaggctcct
    19921 tatccttaaa agcctccata ccgaccagct gcaacgcctg atgaacacgc tctatcatct
    19981 cctgatggga aacacctttg ttttcaagac caaaagcaac gtcatcttcg acagttgcac
    20041 caacaaattg gttatcagga ttttgaaata ccatgccaat tttatgacga atgtcccaga
    20101 cattgtcctc tgtaagaaga tcaccatcaa caaaaatctg gccggcttct gctttcaata
    20161 gcccatcaat taacctaaca acggttgact tgcctgagcc attatgccca atgatagaca
    20221 accactcgcc ttgtttcaca tgaaacgtca catcatctag ggtatatcgc tcctggtcct
    20281 gcttatactt aaatgtaaga ttcttaactt caataatatt tgacattgtt atttaaaggt
    20341 atccttaaaa agaaagcttg ctcctttgaa ataatcgtaa cctgaataaa tcgtaaacaa
    20401 tagagcaata tacagcaaaa cagtgcctaa aacagtccaa tgacacagta aaaagatgat
    20461 ggaaagcatc tgtgctactg ttttgatctt accaggcata gcagctgcta ggaccttatc
    20521 tccagtctca accaatagca aacgaagtcc tgtaacagct agctcacgac agataataac
    20581 cgctgacacc caagccggta ccagctctaa gcccactaac ataataaaag cactcatgac
    20641 aagcatcttg tctgccaatg gatcagcaaa tttaccaaaa ttagtaacaa cctgccactt
    20701 acgtgcaagg taaccatcta aataatcggt caggcttgcc actgcaaaaa taatcgctgc
    20761 aaaggtatgc caaccgactg tctttgaaaa agaggtgatc aacaaaaaca atggaatcat
    20821 gacgatacgg gcgagagtta acaaattggg aatattttct tttttgatca tgcttatacc
    20881 ttattattgt atcttcagtg tgatatagct gatatcagta cttgtcattg ctgataaatc
    20941 taggggctga ccatcaattg ctactgaaac accctttgtt acgcctagtg tcaacaagga
    21001 ttctgttgtc tcagcaggca aggtagtaga ataagtcgga ttgtcctttg ttagggtcat
    21061 accagcctca ccaatttccg aattagtgag ggaaatccaa ctgctctcag catcagtcag
    21121 tgacactgta acatcaacag cttcttttga tttagtaata ttagcaatca agtaattctc
    21181 tgcgccctct gttgtgatca ccgtcttagg ctcagatgag ctggacgctg ttgagtgact
    21241 gctttgtgat gacttaagaa aagacatctc agcctctttt gctttttgac ctttatcaaa
    21301 ttgcttccaa acagcaaaac caataacacc aacaatagcc acagcaataa gacctagtaa
    21361 ggctgatgga aaggctgatt ttttcgtttt agcactattt ccataacgac ttagccttga
    21421 agcactggtc tctctagtcc gtctatggtc agtagcctta aagtgactag ctgtaggagc
    21481 tgatttgctt gaggatagtg acgtcttgac aggaatcact agggtttctg gttgagtcct
    21541 tgaaggctct ggttgagcta ttttttcaga atagctattc tcttgtagcc tttttttgct
    21601 gagcttttct tcaacgattt gtgtgactga tggtgtacct gtttcctttt taaagctcac
    21661 ctgcagctga tacaagcgtt ttaagctatc aaagtctaag ccaacaatat cagcatattg
    21721 ctttagaaaa tgaccaaact tttcttctgg aatgattttg aactggtcaa gctccattgc
    21781 caatagataa tgcgaggaaa tgccagtttt agcttcaatt tcgtctaatg ttatgttttt
    21841 tccgacacgt gtttctctta ataattcacc gagacttgtt tctctcatac gagtacctca
    21901 aaaatattgt aataagacca ttataacaga ttttaagcta tttgggaaag actgtaaaat
    21961 ctgaagtagc tgcatgctca aaaaacaagc ttcctatttc gataatatcc tttaaagcta
    22021 gggtctcaat aatcctagga atatcaaaat aggtctcttg ctctgataaa tgaaggctaa
    22081 attggcttgc cagctgatca atagcgtcta agctttgcat aaaatcccca tacatttcct
    22141 ttttcactag ctctaagtgc tcctcattaa cgtctcttga gcatctaaaa tcggaaatct
    22201 tttttctaat gctgttagac attgcaatag gctgactagt atctgaagaa atcaatacaa
    22261 attggaaatc cctttgaatg tcaacctcta tatcaaagga gtcgtctatc ttgccctttt
    22321 cataccaatc ctgataggtt tttgacgtcc agccaaggag caccgctagg agcagtctaa
    22381 gagctacctg ataggtgagt agagaatact cgcttgacat tagctgaccg cgaaagccga
    22441 ctgctaattt ggcagtcgca acgtccatat caatagatct agacttgatc acagggtagt
    22501 aggtcaatgg agctatctgt acatcatact gcgtctgact tggttgacta tcttgaaagg
    22561 cttcaatagc tgtaaaggct tcttcaatgt caatatcgcc aataatcgtt aagaccatgt
    22621 tagaagggtg ataaaaataa gcatggctgt cagccaataa agagcctgta atgtccctga
    22681 tagactcctt ggtcccagca atatcaacag ctaagctggt attgggaaag aggttctgta
    22741 agataccact gtaagcctga taatcaggat cgtcctgata catctcaatt tcttgagtga
    22801 taatatgttt ttcacgatta accgactcct ctgtaaagct aggagctgct acaaattcct
    22861 gcaaaagtct cagactttct tgccattcat tgacagttga aaagaaatag ctcgttttat
    22921 caaaggttgt aaaggcattt gtttctgatc ctaactgtgt aaatgtaaga gcaatatcat
    22981 taccatcttt atcctcaaat agcttgtgct ctaagaaatg agcaacacct gacggcaagt
    23041 caaacctttg acaattgact gtaaagcttg tgtcaagaga accaaaacga gcagtcagca
    23101 tagctgtttt ctcagaatag ccctctttct ttatcaaata aacccttaaa ccatttgcca
    23161 attgaccgta gtgtaaggtc tctttaatgc tgggatagtc ttttttcagt agtgacgtca
    23221 tcttattttc cctctaaaaa atatacagct tgcagcttga gtagattagc tgtcctgaca
    23281 atatctagct tgctaacctt gtcaatctcg tcaagccaac ttgacaaagt ataggaagga
    23341 tctatataag atctcatgta ttccagctca atcaaggctt tactattatc ctcagatagc
    23401 aaggcgttat tttttagcat tagctttgtt ttcttgacaa ggctgcttga aaagcgcccc
    23461 atcttgatgt cattgagctc tttaaccatt agctgcaggg ctcttgtccg gtgctgtcta
    23521 tctatgccag cataagcctc aaataagcct gtgtaaacat caaatcgact accaatacta
    23581 taggccagcc cctccttctc acgaatttgg gtaaagaagc gagagtgtgt aaaggctcct
    23641 aatagaccat ttaacacaac taaggcataa tactctgctt gcccataaac cagcggaaaa
    23701 tgataggcta gctctaaaac agactgatta agctgctttt gctcgaccaa ttcgttgaca
    23761 acattgacag gctgctgtaa ataaaagaaa tctagctttt tcctgcgtcc ctcaaaggga
    23821 aattggtgta acaattgtac catacgataa tcatcaaaat caccaagaat aaaaatatca
    23881 atctgatcct cattcaacat tttatgaaat tcttgatagc ttgtgtaggc tgtttcttta
    23941 gcaattaact cagtattacc atattttgac agcttcaggc tatcattagc ataaaataat
    24001 tgcttggctt ttagggcact ataataaaag gaatcctcct tatctgcctc gacataggtc
    24061 atcaaatgtc ttttttcgat gtcaaatagt ttgggctggt actgagccac tgataacaaa
    24121 ggagaaaaaa ggatatcctt tagaaattga atcatttcgt ctagaagctt ctctccataa
    24181 aaagcatact gatcctgaat aaaggtaatg tcaatatcca caatatgaac caaacccttg
    24241 gttgacacat gagttgacag gcttgctcca tacatttgtg ctaatttttc tctaaattgc
    24301 ttggcagtag gataggtatc gttagccgtt gctaacattt gagctactaa gactcgcttt
    24361 gctaccgttt tttgattcaa atcacctgaa aagcgaaacg ttatctgatt cgttttaaat
    24421 gttttgtttt ttatcagatg aagctgaact ccctgaataa gtttcataat atttccttat
    24481 taataaatgt gtgatctcta gaattatacc atttttatcg ctattcgttg agtgttaaca
    24541 tcagtctggt agcctatttt gactctttat caaaatgcta tcctgtggct atagtctaga
    24601 ctttagaagg tcagcatttc agcattatta tttagtggct ttttatgcta taatgacttg
    24661 aatgacaaat tggagatgac tatgacatac acactattta ctgactttat taccctacaa
    24721 gctttattaa aggagcaagg tattatccaa agtggtggtg ccattaaagg ttttttagct
    24781 caaacagagg tttttttaaa tggtcaagag gaacaacgac gtggcaagaa gctaagagtc
    24841 ggtgacgtca tcaccattcc atcacagcac atcaagattg agcttgtagc gcctagtcag
    24901 gccgaaaaaa cagcctatga agctgaaaag gcagaaaaag agcgagttgc taagatggtt
    24961 aaacaaatga atcaacaggc taaaaaagca cagaccaagc aagcagctac taccaaaagc
    25021 aagcgtggtc aagctacctc agctgtaaaa gctaagtcta atcaccaaaa gcctattcgc
    25081 ttcccaggat tgtagcatgt ggatcaaaga actaaacctc acccattacc gtaattatca
    25141 acaagcctca gcagcctttt caccgggctt gaatgttttc attggtgaca atgcgcaggg
    25201 caagacaaat tttcttgaag ctatttattt tttgtcagta acaagaagtc atcgcaccaa
    25261 atctgataag gacttaatct actttgacga aagggattgc tctatatctg gaactcttga
    25321 gcgccttagt ggtcgtgttc agctagaaat actgctgtct gataagggac ggatcaccaa
    25381 gattaacacc ctaaagcaag caaagctttc tgattatatc ggagcaatga tggtggtcct
    25441 ctttgctcct gaggatctac agctggtcaa aggctctcct aatcttagac gaaaatttat
    25501 ggacattgac ttaggtcaga taaagcctgt ttacttatca gatttgtcac attacaatca
    25561 tgtcctaaag cagcgaaatg cctatctcaa aagtgttcat cagcttgata atgacttttt
    25621 atctgtgtta gatgagcagc tggttaccta cgggagtcgt gtaatggcgc atcggttggc
    25681 gtttgttcaa tcactagcaa aagaggcaaa caagcatcat caagctatct ctaatggcct
    25741 agagaagctt tcgatctcct atcaagcctc tgtgagcttt gagcaccagc aagagattta
    25801 tcagcaattc atgaaccagc tcaaaaccac tcatcaaaga gatttcttga gaaaaaatac
    25861 tggtgttggc ccccaccgcg atgatctggt tttttatatt aatgacatga acgctaattt
    25921 tgctagtcaa ggccagcatc gtagcctgat tttatcactg aaaatggcag aggttagtct
    25981 gatgaagcaa ttaacaggtg acaaccctat tcttctactt gatgatgtta tgagtgagtt
    26041 agacaatacc agacaaacaa agcttctggg agctgtcaag aaagaaaatg ttcaaacctt
    26101 tatcacaaca actagcttag agcatttgtc tcagctacct aaggacatta gtctctttaa
    26161 ggttaataaa ggaacaatag aacgagattc tatcatgatt gattaactga gcaaactaaa
    26221 aaaagggcac cttaatagtg acccttttta cggttaaatt agttgatact ctatgatttg
    26281 acgataccta agaggatagc gccaacaata aagcaaagga tacctgtaat gacccagcgc
    26341 atctcttttt tggtttttgt ctcacctaag aataaaatac ctccgacaat agagataata
    26401 gcgcccaatt gtgaaaagct aaaagcaatc gccagaccag cctttgaggc tgctagcagc
    26461 atgaagatat ttccaactcc ccaaagcaag ccaacaacac tatttttgat aacatactgg
    26521 tcaaacgata ccttaaacga cataaacatg gctgcaccaa gcaccattcc cactgccatc
    26581 ggtaaaataa ccgacaacac atcaaatttc ataatgttat tgaacagcac agcatacatc
    26641 acatagccgg ttgtcgagta ggttaaggct ctaaagccct ttgaaaaatc atgcaattga
    26701 ttacttgctg cattcgtctc gtcctgcttg cttgaaaaat aaaaaccaac aatcaaaaga
    26761 agtaaggcaa tcgtaccaac gacaaattga ataggcttgg tccactcatg aaagaccagc
    26821 acaccaatca ggctacctaa aactagctga gaaccactag acaagggatt tgctactgaa
    26881 acacccatat actgcatggc atgaaattgc ccagtctgac caacagacca gataatacca
    26941 cctaaaatcc caaaaatcca gagcttcata gacatctcag gtctgactac taaccaaaca
    27001 actagagcaa atagtaaagc tcctatggtc attccaaagg tctgctgtga gggtttaccg
    27061 ccaattttat tactaacaaa gccaatactt ccccatgcaa acattgggac aagtgcaaat
    27121 aaaatacctt ccaaatttac atctccttta caataagttg acacatgatg ttaacgataa
    27181 aagtgctttc atacggagaa ttattatagc ctatttcctt agaaaataca ataacatgat
    27241 gtaaaaaatc atctgctcac acgcttctcc ctaaaaaggt gtcaaagtag ctgacagagc
    27301 ttatttactg caatgctaga ggattattta atgaaaaccg tttgacctta tggctggctc
    27361 tagctggagc tttgttaggg acttttgtga cctgagttcc aaagcaatca gcaactagct
    27421 gactgaaata gcctaagcgt ttgaggagta gagcaagatg attaaccata gcactagctg
    27481 cttgaccgga catgcttgct tctatggtag ctttgacaaa ggatagctca acgatgattt
    27541 tatccagcag tctgccaacc atcttttgac tagtgatgat gtcatctaaa tcaagagcgc
    27601 tgtaaactcc tttttcgatc aatcgactga gatctccatg caagttttga agccgatgcc
    27661 ttgcggtatt gactcgctgt atcgtatcag tcaatgccgg tactagagga catacctcag
    27721 ctctggcaga agcaataccg gatcttatgc ggcaaggata taaagcaccc agatttcccc
    27781 aatagctcct tgtcgttgta gaggtttcat ctttgatttc tgttcgttca acataaaccc
    27841 tatctgaaaa acgtctctct aatactgtca cgatattctt aaagatattc acctcagtag
    27901 tccaataatc aagtgtatca aatagccttg aaaaggttga cgcataaaca gaggcaacct
    27961 ttctggaata gtcccgactc ttttgttcca cctgctcatc aaaggcttgg agaatatctc
    28021 tgacatcatc taaaagacct gttctttcta ggtaagcatc atagctgctt gggacacaga
    28081 cgacatcagc acttccttga aattgaccat tttttaggct gttgcctagc cagttatctg
    28141 tagctgtgac attttgtgat acccctagga tcagctcact ggtattgatt atcatttttt
    28201 ccagctctat gatatcctgt aattccacgc taaatacctc ttttaaggaa tcgctaatac
    28261 cgtcaacttt actttcacgt aaacccgttc cttcaaaggt cttatcactc tccttcaata
    28321 gctgacgact ggcctcatca ataatctgcc aagatttcaa aagtgtcgag cgaccgataa
    28381 tactatcaat ccagcctgac ttttcatgct gagcagatga ggcaagctga agcgattttg
    28441 tgtttaagct cgctaattct gaatcataca tggccagatt gaggcgatta ttattcacat
    28501 atgggatctc atcataggaa aagggatagt ctaggctagc cgaatgagac agcatatcaa
    28561 acaagtcctg ctgaccaact aatctctcca aagaactttg caggctatta aaagtatcgg
    28621 ttaggccatt tgtagcaagc agggctttga tgttttctga aactcgcttt ttcctctctt
    28681 caaaggagtc ttttatggca tcattttttg cctgacattt ttcagtaatg tggcgaatcg
    28741 tttgcaggtc gcctgatata gaggattgaa ggttttgtgc aaggttagtc aggacaccag
    28801 cattgatgac aatcgtttgc ttatcagaaa gcacaccgta ccgagccgat gttgacgaat
    28861 caaagtaatt tctaaagcct aagtacagct cctctacctt agtgtctaat cggttatcgc
    28921 tgtcaatatc aataggcaac aggacattag catgaacaaa ccggccattt acgtctgtca
    28981 tgttgccata ttgatcatac tgatagccat gccacatatg ctgtaagact atatcattga
    29041 ccttttttgt attgacaaca aagacctgac cgactgctcc ctccttttgg tcaaagccca
    29101 taccaatgat gtcatgcgga tccacatagt tgtaaatgcg gtcatgcaag agctttgcac
    29161 gttttctttg atactcatta agcacacgat aggtgttggg gccattgtag atatagactc
    29221 cagagatacg agataagttt ttatcactaa cagaggtaac accgtactga actgtcatgg
    29281 agcctagcga atgaccataa aactcaaatg ttgcgttagg gtattgcttt aatgtcttat
    29341 tggtaaaggt tgctgccttt cggagctgag ctgtcccttt agttggtgtc tggtccggta
    29401 aaagaatgcg catagccata ggcaaatcat tgcctaccca atctgcaacc acatctactg
    29461 ggtgtttctg ccactggtct gggccagtag agccccggta cagcatggtg acatgcttga
    29521 cctgagcata gtctgccttg gtaggatgag ggggaagctt gacatctgtc acgacatagg
    29581 cttgaaaacc tgatatcgaa tcctctatct gagacacata accgatggaa aactcagaat
    29641 tatcatcatc aattaaaact ggtgaaccta ctgtatgttt ttcatactct tcctcagcaa
    29701 tccgttgtct ctgttcgtct gtcaggatca tcattttcac tctcctttta gtagtttttc
    29761 taacttttct gagcgataat tactagcgat ctctaaattt ctttctaaat catatctact
    29821 aaggcgaacc cttaaataag tatctggatc atcattgata atcaggtgaa tagaaaaacc
    29881 tcccctggct tgaatgaact gtgaactgcc ccccaaaagt tagacataaa atctaacaat
    29941 tggggggcta tttttatgac attgagttat gaagacaagg ttcaaatcta tgagctacgg
    30001 cacattggaa agtccattaa atgcttatca gaaaagttta gtattgtaga atctgacctc
    30061 aaatacatga ttcgcctgat tgacaggtat gggttagcca ttgtccaaaa aggtaagaat
    30121 agttattatt ctccagaact gaagcaagag ataatagata aagttctgat tgatggtcaa
    30181 tctcaaaaac agacgtcctt agactatgct ttaccaaatt ctagtatgct ttcaa
//
LOCUS       DARYNN010000027        29140 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.027, whole genome shotgun sequence.
ACCESSION   DARYNN010000027 DARYNN010000000
VERSION     DARYNN010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29140)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29140)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29140
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.027"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            <1..397
                     /locus_tag="TVB59_001140"
     CDS             <1..397
                     /locus_tag="TVB59_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1010040.1"
                     /translation="YVLTGGFLFTGFLLGLSFVLGAALIIYYKQYSEGYEDKKSYNIL
                     QEVGMSKQQVKKTINSQIVLVFFMPIAMAVLHFCVALVMLKQMLFLFGVLDTNLIYLV
                     SALTIAVIIVIYFTIYRITSKTYYNIIER"
     gene            441..1106
                     /locus_tag="TVB59_001141"
     CDS             441..1106
                     /locus_tag="TVB59_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1010041.1"
                     /translation="MIKAGKIYIVEDDAAILTPLKEHLSQNYQVLTVSNFRDIKQEVI
                     DYKPDIILMDITLPFFNGFYWTTEIRKTSTVPIVFISSSNDEMDTVMALNMGGDDFIS
                     KPFSLTILDAKIAAFLRRSQQFSSDDVTIDQFKLHFDGTLSNGTDSIHLSPTEHKILT
                     ILFTHPQQIVSKEDILARLWENESFIDQNTLNVNMTRLRKKISAIGFDCIHTVRGVGY
                     IIK"
     gene            1103..2080
                     /locus_tag="TVB59_001142"
     CDS             1103..2080
                     /locus_tag="TVB59_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL1010042.1"
                     /translation="MIRAFFKEYYSWYIQYGVVMAGYLLIFWLYRLPLGYFKVTSLTI
                     LTLLILQGFGNYIRFKKKMKILQEFIYVKELDQLHSPSEQAYRSLIIKLKEAEAEVAL
                     YQLNNQKNTEALIKMWSHQMKLPLAAMSLMLQTNHIDIKDYQIQVLRLEHYLNNLLSY
                     LKFNQHSDDFRFQVCSVKQLVTSVIKKSSQTCIAKGISIAVDGDWQLSTDNKWLSFAL
                     TQIIDNAIKYSKPQGHIKVSIKEGSIFISDNGIGILEEDLPRLFEEGFTGYNGHEHQK
                     ATGLGLFMTKQILDKLNLNITISSQVDQGTLVVIQKKHSKQTKFSTSLL"
     gene            complement(2180..3250)
                     /gene="xerS"
                     /locus_tag="TVB59_001143"
     CDS             complement(2180..3250)
                     /gene="xerS"
                     /locus_tag="TVB59_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEL1010043.1"
                     /translation="MKRDLLLTKIEEYKNIMPWYVLDYYQSKLSVPYSFTTLYEYLKE
                     YKRFFEWLIDSDLSKAARIADVDLTTLEHLSKKDMEAFILYLRERPSLNIYSTKKGVS
                     QTTINRTLSALSSLYKYLTEEVENEHGEPYFYRNVMKKVATKKKRETLAARAENIKQK
                     LFLGDETMAFLDYVDKEYEYKLSNRAKASFRKNKERDLAIIALLLASGIRLSEAVNLD
                     LKDVNLNMMLVEVTRKGGKRDSVNVAAFAKPHLEAYLSVRKDRYQAEKQDVAFFLTAY
                     RGLPNRIDASSIEKMVGKYSEGFKIRVTPHKLRHTLATRLYDTTKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDKL"
     gene            complement(3407..3844)
                     /locus_tag="TVB59_001144"
     CDS             complement(3407..3844)
                     /locus_tag="TVB59_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEL1010044.1"
                     /translation="MLSKQKLSLEISHYLISGLLTTILYFVFRYVIYSWLHQATISAG
                     FANIIAIIAAFLMNDSYVFKQTSEKRLFRFAMFFLARVVTLGLDMLLAYLLVEKYPEV
                     IGSLVEHDSESINSVESILSQAIMISLNFIVSKYYIFKQHRSR"
     gene            4045..4737
                     /locus_tag="TVB59_001145"
     CDS             4045..4737
                     /locus_tag="TVB59_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1010045.1"
                     /translation="MFSGIQLKTARLSRHISQEQLGQLLGVNKMTISNWEKEKNRPNQ
                     KHFEELVSIFQLPAEYFYQENRLLLPYSQLSASNKEKVISYSESLLEQKEKIIALPAK
                     KKTLYPYRVYERLSAGTGYSYFGDGNFDVVFYDEQLDYDFASWVFGDSMEPTYLNGEV
                     VLIKQDSFDYDGAIYAVEWEEQTYIKKVYREENGLRLVSLNKKYPDKFASFDDNPRII
                     GKIIANFMPLDV"
     gene            complement(5113..5589)
                     /locus_tag="TVB59_001146"
                     /pseudo
     CDS             complement(5113..5589)
                     /locus_tag="TVB59_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515631.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(5802..7364)
                     /gene="guaA"
                     /locus_tag="TVB59_001147"
     CDS             complement(5802..7364)
                     /gene="guaA"
                     /locus_tag="TVB59_001147"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEL1010046.1"
                     /translation="MTEISMLNDIQKIIVLDYGSQYNQLIARRIREFGVFSELKSHHI
                     TAQELRDINPIGIVLSGGPNSVYATDAFGIDPEIFELGIPILGICYGMQLITHTLGGK
                     VVPAGQAGHREYGQSSLRLRSASALFAGTPDEQLVLMSHGDAVTEIPEGFHLVGDSND
                     CPYAAMENTKKRLYGIQFHPEVRHSVYGNDILKNFAISICGGRGDWSMDNFIDMQIAK
                     IRETVGDRKVLLGLSGGVDSSVVGVLLQKAIGDQLTCIFVDHGLLRKNEGDQVMEMLG
                     GRFGLNIIRVDASKRFLDLLAGVEDPEKKRKIIGNEFVYVFDDEASKLKGVDFLAQGT
                     LYTDIIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGTALGMPDEV
                     VWRQPFPGPGLAIRVMGEITAEKLETVRESDAILREEIAKAGLERDVWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAQLPWEVLKKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            7651..8349
                     /locus_tag="TVB59_001148"
     CDS             7651..8349
                     /locus_tag="TVB59_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1010047.1"
                     /translation="MLPAYIKIHDAIKKDIEKEVWTIGSRLPSERDLAEHFEVSRMTL
                     RQAITLLVEEGILERRVGSGTYVASHRVQERMRGTTSFTEIVNSQGRKPSSKLISYQR
                     QLASDTEINQLHLEESDYVIRMERIRYADKVPLVYEVASIPEKFIKNVKKTDITEHFF
                     QTLTSNGYEIGKSQQTIYAKIASERVASYLEVAKGHAILALTQVSFFTDGRPFEYVRS
                     QYVGDRFEFYLENN"
     gene            8561..8893
                     /locus_tag="TVB59_001149"
     CDS             8561..8893
                     /locus_tag="TVB59_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEL1010048.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEAYEMKLHMYSDYIVRSEIFDDILAKYPSDHYLRDKISI
                     LTSIDNRD"
     gene            8908..10479
                     /gene="ffh"
                     /locus_tag="TVB59_001150"
     CDS             8908..10479
                     /gene="ffh"
                     /locus_tag="TVB59_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEL1010049.1"
                     /translation="MAFESLTQRLQDVFKHIRGKKTLSEADVQEVTKEIRLALLEADV
                     ALPVVKTFIKRIRERAVGHEIIDTLDPTQQILKIVNEELTGILGSETAELDKSPKIPT
                     VIMMVGLQGAGKTTFAGKLANKLIKEENARPLMIAADIYRPAAIDQLKTLGQQINVPV
                     FDMGTNHSAVDIVANGLAQAKENRHDYVLIDTAGRLQIDEKLMGELREVKALAKPNEI
                     LLVVDSMIGQEAANVAYEFNNQLDITGVVLTKIDGDTRGGAALSIREITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDLLTLIEKASQEYDEKKSLELAAKMRENTFDFNDF
                     IEQLDQVQNMGPMEDLLKMIPGMATNPALANIKVDDKQIARKRAIVSSMTPEEREQPE
                     LLTPSRRRRIAAGSGNSFVEVNKFIKDFNQAKAMMQGVMSGDMTKMMKQMGINPNNLP
                     KNMPNMPGGMPDMSALEGMMGQGGLPDMSALGGDMDMSQLFGGGLKGKIGQFAMKQAM
                     KRQANKIKKAKKKRK"
     gene            complement(10632..11855)
                     /locus_tag="TVB59_001151"
     CDS             complement(10632..11855)
                     /locus_tag="TVB59_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyltransferase"
                     /protein_id="HEL1010050.1"
                     /translation="MINVAFNSKIGISAQEHDQFVKQHQQVNLLQSSSWAAVKNQWQN
                     ERIGIFQGDNQVASMSLLIKPLPFGMTMIYIPRGPVMDYTNADLVAFTIKTLKAYGKK
                     KRALLIKFDPMILLKQHQLGEKAPDNSKALTIIKHLKRFGAHWTGPTTKLSDTIQPRF
                     QANCYTNADIEASFPKHTKRLMKDARQRGVIAYRGNQSDLHTFADLISLTEKRKGVAL
                     RNEAYFRQLMTTYGDNAYLHLAKVNLPEKLKNYELQLKAVEQELAQTQAHQKKRLARL
                     TDQKQSLQRYLSEFKDFLDKYPDEVVIAGILSISYGNTMEMLYAGMNDDFKKFYPQYL
                     LYPKVFMDAYHDDIAWANMGGIDGSFKDGLTAFKSNFSPTIEEFIGEFNLAISPFYHL
                     ANLLYKIRKQLKHRH"
     gene            complement(12080..13051)
                     /locus_tag="TVB59_001152"
     CDS             complement(12080..13051)
                     /locus_tag="TVB59_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEL1010051.1"
                     /translation="MTYQKKLIAASMALASVFMLQTVHAAANNVQQVIDETYVQPDYV
                     LGYSLSAEQREQTLALLHYNSASDNKLSTLNTTAYASIMNVADDPSLQLYSSVRIQKL
                     GAKETLKVTIVTPENITKVTQDMYRNAAVTLGIEHANITVAAPIPVTGESALAGIYYS
                     LEKNGAKVPEENKKLAQEELSTLSNINTENAGKTGYDADKLNVALTDIKAAVAKAGEG
                     VNEEKVRQIVTETLDHYGLTKAVTPDQINLIINFALNLSNSGVISNENFTKTLNALKD
                     SIVEKAGSTFKNINVNFDATEALKTGQGILQQIIDFFRGLIDSLMGN"
     gene            complement(13364..13804)
                     /locus_tag="TVB59_001153"
     CDS             complement(13364..13804)
                     /locus_tag="TVB59_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEL1010052.1"
                     /translation="MTKKAYLSLFTILLLFPLSACDFKAQDSTGKKLKSSHQLEKRCK
                     ALKKETDKSPNEVSKEEGIAAEQIIVSISDDGFVTSHGDHYHFYNGEVPYDSLFSSEL
                     LPPKDYQFDQKDVINEVKNGYVIKTDDHYYFYLKDNNHQENLRS"
     gene            complement(13801..14736)
                     /locus_tag="TVB59_001154"
     CDS             complement(13801..14736)
                     /locus_tag="TVB59_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HEL1010053.1"
                     /translation="MIRGFKKTIVAVGLLAVLLGLSACHQSSSSRKAGLVIKTSFYPI
                     YAMTKEICGDLNDVQVIAQNTSIHSYEPSPTVVAKVYDGDVFIYHSKILEAWAADLAP
                     QLEKKGLAVMEGTSHLTLDKVQGLEHFTIKKGMNTDALYDPHTWTDPILASQEAEQIA
                     ALLSQKDPAHKAVYLQNAKRFKAKAQKLVKTYKEKFESLGRKTFVTQHTAFSYLAKRF
                     DLKQLGIAGISPEQEPSPRQLAQIDRFIKKYDVKTIFVEENASDKLAKTLAQSNGVAI
                     DILSPLEVVPADQKTYLEHLKMNLETLYRVLESET"
     gene            complement(15174..15587)
                     /locus_tag="TVB59_001155"
     CDS             complement(15174..15587)
                     /locus_tag="TVB59_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEL1010054.1"
                     /translation="MELKAIHHIAIIVSDYEVSKDFYVNKLGFEIIRENHRPDRHDYK
                     LDLKCGAIELEIFGNKKTDPAYQAPPKRIGRPEYDKEACGLRHLAFHVKPIEAYIEQL
                     MAKGIAVEPLRYDDYTGKKMTFFFDPDGLPLELHE"
     gene            complement(15685..16440)
                     /locus_tag="TVB59_001156"
     CDS             complement(15685..16440)
                     /locus_tag="TVB59_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase"
                     /protein_id="HEL1010055.1"
                     /translation="MAKRTHRRRQKRRKMSFARGILVVLLLIIGLALLFNKPIRNTLI
                     AWNSNKYQVTKVSKKTIKKNKEAKSSFDFQAVQPVSTESVLQAQMDAQQLPVIGGIAI
                     PELGINLPIFKGLGNTELIYGAGTMKEDQVMGGENNYSLASHHIFGLTGSSEMLFSPL
                     ERAKEGMSIYLTDKERIYEYEINAVFTVTPERIDVINDTPGLKEVTLVTCTDYEATER
                     IIVKGAIKNEYEFNKAPDDVLKAFNHSYNQMST"
     gene            complement(16445..18940)
                     /gene="gyrA"
                     /locus_tag="TVB59_001157"
     CDS             complement(16445..18940)
                     /gene="gyrA"
                     /locus_tag="TVB59_001157"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEL1010056.1"
                     /translation="MQDKHLVDVNLTSEMKTSFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRHMLVD
                     GHGNFGSMDGDGAAAQRYTEARMSKIALELLKDINKNTVDFQDNYDGNEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLAEAIDAVKMVMENPDCTTRDLMEVLPGPDFPTG
                     ALVMGRSGIHKAYETGKGSIVLRSRTEIETTSTGRERIVVTEFPYGINKTKVHEHIVR
                     LAQEKRIEGITAVRDESSRQGVRFVIEVRRDASANVILNNLFKLTSLQTNFSFNMLAI
                     EGGIPKILSLRQIIDNYILHQKDVITRRTQFDKDKAEARAHILEGLLIALDHLDEVIA
                     IIRNSETDIIAQAELMSRFDLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILARPERIEAIIKEEMEEIKRKYANPRRTELMIGEVLSLEDEDLIEEEDVLITLS
                     NNGYIKRLAQDEFRSQKRGGRGVQGTGVNDDDFVRELVSTSTHDTLLFFTNFGRVYRL
                     KAYEIPEYGRAAKGLPVINLLKLDDGETIQTIINAKKEDILDKYFFFTTKQGIVKRTE
                     VSEFSNIRQNGLRALNLKEGDELINVLLTNGQEDIIIGTRSGYSVRFNEATIRGMGRS
                     ATGVRGVKLREEDWVVGASRINDKQEVLVITENGYGKRTSAAEYPTKGRGGKGIKTAN
                     ITAKNGQLAGLMTVDGSEDIMVITTKGVIIRTNVSSISQTGRSTLGVKVMRLDTDSKI
                     VTFTLVQAEDNDPTAIAQTDTALTEAPINSSKE"
     gene            19132..20115
                     /locus_tag="TVB59_001158"
     CDS             19132..20115
                     /locus_tag="TVB59_001158"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEL1010057.1"
                     /translation="MTATKQHKKVILVGDGAVGSSYAFALVTQNIAQELGIIDIFKEK
                     TQGDAEDLSHALAFTSPKKIYAADYADCHDADLVVLTAGAPQKPGETRLDLVEKNLRI
                     NKEVVTQIVASGFKGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFRQAL
                     AAKIGVDARSVHAYIMGEHGDSEFAVWSHANVAGVGLYDWLQANRDVDEQGLVDLFIS
                     VRDAAYSIINKKGATFYGIAVALARITKAILDDENAVLPLSVFQEGQYEGVEDCYIGQ
                     PAIVGAYGIVRPVNIPLNDAELQKMQASANQLKTIIDEAFSKEEFASAAKN"
     gene            complement(20320..21687)
                     /locus_tag="TVB59_001159"
     CDS             complement(20320..21687)
                     /locus_tag="TVB59_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEL1010058.1"
                     /translation="MSKIVVIGANHAGTACIKTMLTNYGDANEIVVFDQNSNISFLGC
                     GMALWIGEQISGPEGLFYSNKEELESLGAKVYMESPVQSIDYDAKTVTALVDGKEHVE
                     SYDKLIFATGSQPILPPIKGAEIKEGSLEFEATLENLQFVKLYQNSADVISKLENKDI
                     KRVAVVGAGYIGVELAEAFQRKGKEVILIDVADTCLAGYYDRDLTDVMSKNLEEHGIQ
                     LAFGETVKEVAGDGKVEKLITDKNEYDVDMVILAVGFRPNTALGAGKIELFRNGAFLV
                     NKHQETSIPGIYAIGDCATIYDNATRDTNYIALASNAVRTGIVAAHNACGTALEGIGV
                     QGSNGISIYGLHMVSTGLTLEKAKCLGFDAAVTEYTDNQKPEFIEHGNFQVTIKIVYD
                     KESRRILGAQMASHEDISMGIHMFSLAIQEGVTIEKLALTDIFFLPHFNKPYNYITMA
                     ALGAE"
     gene            complement(21937..22539)
                     /locus_tag="TVB59_001160"
     CDS             complement(21937..22539)
                     /locus_tag="TVB59_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HEL1010059.1"
                     /translation="MFRVLKRILGLAVLIFCLYEAVTIHKNVHRVLQYKPTVERILAE
                     NGNKADVDLVLAMIYTETKGGEADVMQSSESSSGIRDSITDSQSSIEYGVRLLSHNLA
                     LAEKAGVDPWTAVQAYNFGTAYIDYVAKNGGQHTIELATNYSRTVVAPSLGNTTGKTY
                     FYYHPLALLSGGKLYCNGGNIYYAQEVHVNLYLIELMSLF"
     gene            complement(22540..23517)
                     /locus_tag="TVB59_001161"
     CDS             complement(22540..23517)
                     /locus_tag="TVB59_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEL1010060.1"
                     /translation="MLDIYIKGIVIHQFTPNDTELILSDALVAITPRIDEYFRKKLAK
                     VFSDDAKRGQLEADHAFFTTIGTELLETSVTIAKLWKEEFVASEHQKTNDLVFIQFDK
                     EGVPYLAFLRIALKEHFAHLSDDHENPITITQNNLPSPTQAPDEALVINRQTGYYYLI
                     EKRMKHNGSFAHYFSEKLLKVTPEQSVKKSIQMLEQTAQKVAENFNQDDFAFQSKMKV
                     ALAKNLEEETALSPEKLADQLFDQNLTARLTFVDQVKEMIPEPIQVSDIDHSRQLKKL
                     ETQKLSLSNGIELLVPNAVYQDAESVEFILNDNGTYSILIKNIEDIKNN"
     gene            complement(23520..24779)
                     /locus_tag="TVB59_001162"
     CDS             complement(23520..24779)
                     /locus_tag="TVB59_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEL1010061.1"
                     /translation="MMFNNENYKDYDQELWEAIQAEEDRQEHNIELIASENMVSKAVM
                     QAQGSVLTNKYAEGYPSKRYYGGTEYVDIVESLAIERAKKLFGAAYANVQPHSGSQAN
                     AAAYMALINAGDTVLGMDLAAGGHLTHGSPVNFSGKTYQFVGYTVDKETEKLDYAAIL
                     KQAKAVQPKLIVAGASAYSRQIDFEQFRFIADQVGSYLMVDMAHIAGLVAAGLHQNPV
                     PYAHIVTSTTHKTLRGPRGGLLLTNDEAISRKMNAAIFPGLQGGPLEHVIAAKAVAFK
                     EALDPAFTDYARAVIANTAAMAEVFAKDDRFRLISGGTDNHLFLVDVTKVIENGKLAQ
                     ALLDEVNITLNKNAIPFETLSPFKTSGIRIGCAAITSRGMGVDESRTIAHLIIKALVN
                     HQQPEILEEVRYEVRRLTDAFPLYKKN"
     gene            complement(24791..25222)
                     /locus_tag="TVB59_001163"
     CDS             complement(24791..25222)
                     /locus_tag="TVB59_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1010062.1"
                     /translation="MLRPLDQTDCQAICDINDQSLGYKVSLELTKSQLEKLRSDKHHY
                     LLGYADTKTNLLLGYLHAECYESLYSEKGFNILALAVRLDHQGRGIGRRLLAALEEKA
                     KQEKVSFIRLNSASHRTEAHAFYRKLSYVDDKTQLRFMKLL"
     gene            complement(25236..25829)
                     /locus_tag="TVB59_001164"
     CDS             complement(25236..25829)
                     /locus_tag="TVB59_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEL1010063.1"
                     /translation="MITHLIETIKAGGALILPTETVYGLFAQALNEEAVNAVYRLKKR
                     PRDKAMNLNVADFESILAFSKQQPAYLNKLYEAFLPGPLTIILKANAQTPYWINSGLK
                     TVGFRLPSHPLTAKIIRATGPLIGPSANLSGSKSGKCFNDIVKAFDGKVDGYADDAYL
                     TGKDSTILDLSSPKVSILRQGAITKEQLLAKVPELPF"
     gene            complement(25801..26649)
                     /gene="prmC"
                     /locus_tag="TVB59_001165"
     CDS             complement(25801..26649)
                     /gene="prmC"
                     /locus_tag="TVB59_001165"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEL1010064.1"
                     /translation="MNYAKQLRAYEDRLENIGEDRENLAYVFKELKQWTSLDFLLHQN
                     QEVTSEDQALLERIFLALSQHVSPQYITGRAYFRDLVLAVDSRVLIPRPETEELVELI
                     LKENDATRKSVLDIGTGSGAIAIALKKARPNWQVTASDISADALSLAYSNALDHHVEI
                     AFEQSDLFSKLSGQFDIIVSNPPYIAYEDKDEVGLNVYQSEPHLALFAAENGFSIYRR
                     IIEQASAYLTTSGKLYFEIGYKQGEGLKRLLSKRFPQKRIRVLKDMLGKERMVVVDDN
                     TFDRDN"
     gene            complement(26646..27728)
                     /gene="prfA"
                     /locus_tag="TVB59_001166"
     CDS             complement(26646..27728)
                     /gene="prfA"
                     /locus_tag="TVB59_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEL1010065.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPEVVSDTKRFMALSKEEASTR
                     ETVAAYRQYKAIIQSIDDAEEMIKEAGGDPDIEEMAKEELKEAKSAKEAYEDKLKLLL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLAMYQKFAESQGWRFEVMEASYNGVGG
                     IKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRIDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNRDKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEIVDALVLYDQTQKLESLNNQ"
     gene            complement(27770..28339)
                     /locus_tag="TVB59_001167"
     CDS             complement(27770..28339)
                     /locus_tag="TVB59_001167"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEL1010066.1"
                     /translation="MAQLYYKYGTMNSGKTIEILKVAHNYEEQGKPVVIMTSALDTRD
                     GFGIVSSRIGMRREAVPISNDMDIFAFIAELQEKPYCVLIDECQFLSKQNVYDLARVV
                     DELNVPVMAFGLKNDFQNELFEGSKYLLLLADKIDEIKTICQYCSKKATMVLRTEHGK
                     PVYEGAQIQIGGNETYIPVCRKHYFHPPI"
     gene            28526..28711
                     /locus_tag="TVB59_001168"
     CDS             28526..28711
                     /locus_tag="TVB59_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEL1010067.1"
                     /translation="MPFVTIDLFEGRSQEQKIALAREVTEVVSRIAQAPKEAIHVVIN
                     DMPEGTYFPHGEMKTKA"
     gene            28766..>29140
                     /locus_tag="TVB59_001169"
     CDS             28766..>29140
                     /locus_tag="TVB59_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEL1010068.1"
                     /translation="MIATDQIKMMGTIIDICIDSSKAKQQAATIRELLTLYNHRFSAS
                     DDSSELMAINHMAGIQPVRVHSDLFDLISIGKEHSLAYPSNLNITLGPLVQSWRIGFS
                     DAKLPDEATIDRRLRLTNPNHII"
BASE COUNT         8613 a         6030 c         5495 g         9002 t
ORIGIN      
        1 ctatgtccta accggtggct tcctttttac aggctttctt ttaggcttga gctttgtact
       61 tggggctgca ctgatcattt attacaagca atactctgaa ggctatgagg ataaaaaatc
      121 ttacaatatt cttcaagagg tcggcatgag caaacaacaa gtcaaaaaaa ccatcaattc
      181 ccaaattgta ttagtgttct ttatgcccat agctatggca gtcctacatt tttgtgtcgc
      241 tctggttatg cttaagcaaa tgctctttct ctttggcgtt ttagacacta atcttattta
      301 cctagttagt gcgctgacca ttgctgttat tatcgttatt tactttacta tttacaggat
      361 aacaagcaaa acctattaca atattattga aagataagac gagtggcgat ttttcgccac
      421 ttttttgata aaataatatt atgattaaag ctggaaaaat ttatattgtc gaagatgacg
      481 ctgctatctt aacaccctta aaagagcatc tgagtcagaa ctaccaggtt cttaccgtct
      541 ctaactttag agacattaag caagaggtga ttgattataa accggatatc atccttatgg
      601 acatcacctt accgtttttt aacggctttt actggacaac agaaattcgt aaaacgtcaa
      661 cagtgccaat tgtttttatc tcaagcagta atgatgagat ggatacggtc atggcactta
      721 atatgggggg agatgatttc atctctaaac ccttttctct aaccatttta gacgcaaaaa
      781 tcgcagcctt tttaagacgc tcacagcaat ttagcagtga tgatgtgacc atagatcaat
      841 ttaagctaca ttttgatggc accttatcta atggcacaga tagcattcat ttatcgccaa
      901 cagagcacaa aatcttaacg attttattta ctcacccgca gcaaattgtt tcaaaggagg
      961 atattctagc aaggctttgg gaaaacgaga gctttattga tcaaaacacg cttaatgtta
     1021 acatgacgcg tctacgcaaa aaaatatcag ctattggttt tgactgtatt cacacagtga
     1081 gaggagtagg ctatattatc aaatgataag agcatttttt aaggaatatt attcctggta
     1141 tatccagtat ggggttgtta tggctggtta tctgctgatc ttttggcttt ataggcttcc
     1201 tttaggctat tttaaagtga ctagcctaac catactaacc ttgctaatat tgcaaggttt
     1261 tggaaactat attaggttca aaaagaagat gaagatttta caagaattta tttatgtaaa
     1321 agaactagat cagctgcact cccctagcga acaagcctat aggtctttga ttattaagct
     1381 taaggaagca gaagcagagg tagcactgta ccaacttaac aaccaaaaga atacagaagc
     1441 actgattaaa atgtggtctc accaaatgaa gcttccccta gcggctatgt ccttaatgct
     1501 tcaaaccaat catattgata ttaaggatta tcagattcag gttctacgct tggagcatta
     1561 cctcaacaat ctattaagct atttgaagtt taaccagcat agtgatgatt ttcggtttca
     1621 ggtttgctct gtaaagcagc ttgtgacctc agttatcaaa aagtccagcc agacttgtat
     1681 cgctaagggg attagcattg cagttgatgg cgattggcaa ttgagcactg acaacaaatg
     1741 gctgtcattt gctctgacac aaatcattga caatgcaatc aaatattcta agccacaagg
     1801 ccacatcaaa gtcagcatta aggaaggcag tatttttata tcagataatg gtattggaat
     1861 actagaggaa gatttgccac gtctgtttga agaaggcttt actggctaca atggccatga
     1921 gcatcaaaag gcaactggtt taggcctctt tatgacaaag caaatccttg ataaattaaa
     1981 tttaaacata actatttcca gtcaagttga ccaaggaact ttagttgtaa ttcaaaaaaa
     2041 gcattctaaa cagaccaaat tctcgacttc tttgctgtaa aaaataacag ctataaatcc
     2101 ctataatagt gacaaagagg attaaaacat tgcaaaaaaa gactgaaagt acagattaca
     2161 taattttagt tatgtaaatt tataatttat ctagggcatt tttttgctca tcgttaacaa
     2221 tatgagtata gaggtctgta acttgggtcg aggcatgacc aagctgatga cttactagga
     2281 cctgtgactt tgtagtatca taaagtctcg ttgcaagcgt atggcgtagc ttatgaggag
     2341 ttacacgaat tttaaagcct tcagaatatt tacctaccat tttttcaatg cttgaggcat
     2401 ctatccgatt ggggagccca cgataggctg ttaaaaagaa ggctacatcc tgtttttctg
     2461 cttgatagcg gtcttttcga actgataaat aggcttctaa atgaggcttg gcaaaagcag
     2521 caacattgac cgaatctctc ttacctccct tacgggtaac ctcaaccagc atcatgttga
     2581 ggttgacatc cttaaggtct aggttaactg cctcggataa ccgaatacca gatgccagca
     2641 gtagggcgat aatggctagg tcgcgttctt tattttttcg gaaagaagcc tttgcccgat
     2701 ttgacagctt atattcatat tctttatcca catagtctaa aaatgccatc gtctcatcgc
     2761 ctaaaaaaag cttttgttta atattttcag ccctggctgc taaggtttct cttttctttt
     2821 tggttgccac ctttttcatg acatttcgat aaaaataagg ctctccatgc tcattttcaa
     2881 cctcctcagt aaggtattta tacaagctgg atagtgcaga aagggtacga ttaatggtgg
     2941 tttgcgatac ccccttttta gttgaataga tgttcaagga aggacgctca cgaagataga
     3001 gaataaaggc ttccatatcc tttttactca aatgctccag agtagtcaag tccacatcag
     3061 caatcctagc agcttttgat agatcagaat caattaacca ctcaaaaaag cgtttgtatt
     3121 ctttcaggta ttcgtacaag gtcgtaaagc tataaggaac agatagctta gattgataat
     3181 aatcaaggac ataccaaggc atgatgtttt tgtattcttc aattttagta agtagtaaat
     3241 cacgtttcat aataaattct cacaatgttt cgtcaacaaa tgaattatcc attggatatc
     3301 agactgatag tagtatatca catcttgggg tatttttcaa gaaaattata gtttttcgga
     3361 aagatataaa attatttaat agttattttg ctaagctaag gctgttttat ctgctacgat
     3421 gctgcttaaa aatatagtat ttactaacaa taaaattcaa gctaatcatt atggcttggc
     3481 tcaaaatgct ttcaacagaa ttaatgcttt cagaatcatg ttcaacaagg cttccaatga
     3541 cctctgggta tttttcgact aataaatagg ctaatagcat atctaagcct aatgttacta
     3601 ctctagctag gaaaaacatg gcaaatctaa acaagcgttt ttcagaagtt tgcttaaaaa
     3661 catagctatc gttcatcaag aaggcagcta tgatcgctat aatattggca aagcctgctg
     3721 atatggtggc ctgatgtaac catgaataga tgacataccg aaaaacaaaa taaagaatgg
     3781 ttgttagaag accagatatc aggtaatgac tgatttcaag tgataatttt tgtttgctaa
     3841 gcatttttct ttcctatgtg tatttatctt gactgttata ttttgatgga tctatataag
     3901 tataacatgt ttggcattaa acctaagaca gcttactgtc ttttcgatat aaacataaaa
     3961 agcttgaata ttcttataag ctatgttata ctctggtaaa gttaatactt tactagagta
     4021 tactgacaaa ggagatttat gctgatgttt tctggtattc aattaaaaac agcacgttta
     4081 tcaaggcata ttagccaaga acagctagga cagcttttag gagttaataa aatgactatt
     4141 tccaattggg aaaaggagaa aaatagacca aatcaaaagc attttgaaga gcttgtgagc
     4201 atttttcaat tacctgctga gtacttttat caagaaaatc gtcttttact tccctatagt
     4261 cagttaagcg cctctaataa agaaaaagtt atcagctatt ctgagagctt acttgaacaa
     4321 aaagaaaaaa taattgcttt accagctaag aaaaagacac tttaccctta tcgtgtttat
     4381 gaaaggttgt ctgcagggac tggctattct tactttggtg atggtaattt tgatgttgtc
     4441 ttttacgatg agcagttaga ttatgatttt gcttcatggg tttttggtga ctccatggag
     4501 ccaacctatt tgaatggcga ggttgttctc atcaaacagg atagctttga ttatgacggt
     4561 gctatctatg ctgttgagtg ggaagaacaa acctatatca aaaaagtata tcgtgaagaa
     4621 aatggtctgc gtttggtttc attgaacaaa aaataccctg ataaattcgc ttcctttgat
     4681 gacaatccgc gtattattgg aaaaatcatt gccaacttta tgcccttaga tgtataagcc
     4741 tttgtattag cttaaaagca tgactgttgt acaaccaaac tcattgcatg acattggtgc
     4801 attatttttg aagtggcttc tacttctttg atttactttt ctgcattaaa aagcccatta
     4861 aaggtttttg aaacttatta cttagacaaa ggctctatta aaaatcataa ccaaccggtg
     4921 gtggtttatt tgtcatgtac cttgcatttt gtgacagact tcataaaacg aacaaaacac
     4981 atcgctaaaa gattttacca tcttaaagtt atgtgttttt tgtataaaaa cttatctata
     5041 tgcttgatta accaactgag ataaatagat tattatttca tagagaagtt tgttatctaa
     5101 tccaaataat cgtattatcc tcttaagttc ctcaacatta taaccatcac aatctgttgg
     5161 cagtttattt ttttcaagcc acttatcaac cactgctatt cccaaagaaa ttgaaaaatc
     5221 tttttcttta tcaaacttac acaattccac tgccaaagtc aatacaaaat tcctgtgaat
     5281 attatcgtaa ttttcatcaa ataattgcct ttccaaaccc acaatagata gccgactaaa
     5341 tatgtatctc cctatttctt cgtcaatacc ttcagtagcc ttaatagctt cttggacaac
     5401 attattccag aaagcatttt tattacgctc ttctataaaa gttttaagtt tcattttgaa
     5461 aatatcagta atttgaccaa ctgctttatc aataacctat gaaacaatat tcttcatcat
     5521 tatgattttc tcctcgtata cataaataat tgtatctttg ctatataatt gtggtatctc
     5581 ttcaatcaac caatattgtt cttaaactat tccctcaaaa gccttccacc aaaacgatgg
     5641 aaggctttta aaccattcac ctaaattcaa caactccctt ttgaacttgc tattttagct
     5701 ttttagtatc aaagcagtat cactcaagag ttttttgttt ccacaaaccg caaaaaccca
     5761 ctgttttcaa cactttcatg gcagtaatat atttgcttct gtcactccca ctcaacggtt
     5821 gctggtggtt tgctggtgat gtcgtagaca atgcgattaa cgtggtcgac ttcattgaca
     5881 attcgaactg agattttctt tagaacttcc caaggcaatt gggcaaagtc tgctgtcata
     5941 ccatcaattg aggtgatagc acgaatagcg atggtatagt cataggtgcg accatctccc
     6001 ataactccga cggaacgaac acctgtgtta actgtaaaat attgccacac atcacgctca
     6061 agtcctgctt tagcaatttc ttctcgaagg atagcatctg actcgcgaac tgtttcaagc
     6121 ttttctgctg tgatctctcc catgacgcga atggcaaggc ctgggcctgg gaaaggctga
     6181 cgccagacga cttcatctgg cataccaagg gccgtaccaa gagcacgaac ctcatcctta
     6241 aagagtgtat tgaggggttc gattaattca aactgcatat cctctggcag accaccaaca
     6301 ttgtggtgag attttatcgt ttgagcagtt tctgttccag attcaatgat gtctgtgtaa
     6361 agcgttcctt gtgcaaggaa gtcaacgccc ttaagcttgc tagcctcgtc atcaaagacg
     6421 taaacaaact cattaccgat aattttacgt tttttctcag gatcctcaac gcctgcaaga
     6481 agatctaaaa agcgctttga ggcatcaaca cgaataatat tgagaccaaa tcttccacca
     6541 agcatttcca taacttggtc accttcattt ttacgaagaa gtccatggtc aacaaagata
     6601 caggttaatt gatctccgat agctttttgt aaaaggacac caacaactga agaatcaaca
     6661 ccaccagaca aacctagcaa aaccttacga tctccgactg tttcgcgaat tttagcaatt
     6721 tgcatgtcaa taaaattatc cattgaccaa tcaccacgtc caccacagat agagatagca
     6781 aagttcttca aaatatcatt accatagaca gagtgtctta cctctgggtg gaattggata
     6841 ccgtagagcc tcttttttgt attttccata gcagcgtaag ggcaatcgtt agaatctcct
     6901 acaagatgaa agccctctgg gatttctgta acagcatcac catgactcat caaaacaagc
     6961 tgctcatctg gagtgcccgc aaataatgct gatgcagaac gtaaacgtaa tgatgattga
     7021 ccatattctc ggtgacctgc ttgaccagct gggactacct tacctcctaa ggtatgtgtg
     7081 attagctgca tgccatagca aatccctaaa attggaatcc ctaattcaaa gatttcagga
     7141 tcaataccaa aggcatcagt tgcataaaca gaatttggcc caccagacag gacaatcccg
     7201 attggattga tgtcacgaag ctcttgcgca gtgatgtgat ggcttttgag ctcagaaaaa
     7261 acaccaaact cccgaatacg tcttgcaatc agttgattgt actgactacc ataatcaaga
     7321 acgataattt tttgaatatc attcaacatt gaaatttcag tcattataac cctttcatta
     7381 tataccagaa ccttgttagc tgatagtttt caattaattg tagcatattt tcactaaaaa
     7441 ggcattagct tttcaggtga tgtgatgaaa aaataagctt tttgcagaga tattaaaatg
     7501 aatgacctca actatcttat gtatgactac tattgtcagt cttagcatga aaaagctgat
     7561 tgatgatgag tgtttttggt aataattggg ctgctattta ggctgaaaat atgataaaat
     7621 aaaaccatca tcaccctcaa ggagtaaagc atgctgccag cttatataaa aattcatgac
     7681 gctattaaaa aagacatcga aaaagaagtt tggactattg gtagtcgcct gccaagcgaa
     7741 cgagatttag cagaacattt tgaggtcagt cgcatgacgt tgcgtcaggc aataacactg
     7801 cttgtagagg agggaattct agaaaggcgt gttggtagtg gtacttatgt tgccagccat
     7861 cgcgtacaag agagaatgcg tgggaccact agctttacag agatcgtgaa ttctcaggga
     7921 cgtaagccat cttcaaaact gatttcctat caacgtcagc tagcaagtga tacagaaata
     7981 aatcaattgc acttagaaga atcagattac gttattcgaa tggagcgcat tcgttatgca
     8041 gataaggttc ccttagttta cgaggtagca tctattcctg agaaatttat taaaaatgtc
     8101 aaaaaaactg atattacaga gcactttttc caaaccctaa cctcaaacgg ttatgaaatc
     8161 ggcaaaagtc aacaaaccat ttacgcgaaa atagccagtg agcgtgtcgc ctcttatcta
     8221 gaggtcgcta aggggcatgc tattttagca ttgactcagg tttccttttt tacagacggt
     8281 aggccctttg aatatgtgcg tagccaatat gtaggtgatc gctttgaatt ttatttagaa
     8341 aataattaat cataagcaat gatgtttaaa taacattgat aggaagtggc tcaccacttc
     8401 tttttttcaa cacttgtcaa gtatatcaat atttcaagaa cagttattaa aacaagctac
     8461 tattatcctc atttttgctc taagaaagct tcctgataaa aggctgatcg ctatcattta
     8521 ccactgttaa aaatgctcat gatgtgataa aatgaagatt atggaaattg aaaaaacaaa
     8581 ccgaatgaat gctctttttg aattttatgc tgccttattg actgataaac agatgaacta
     8641 tatcgagctc tattacgctg atgattatag tctggctgaa attgctgaag aattcggtgt
     8701 cagccgccaa gcagtttatg ataatattaa gcgcactgaa aaaattctgg aagcctatga
     8761 aatgaagctt catatgtatt cagattatat tgtacgtagt gaaatatttg atgatattct
     8821 tgcaaaatat cccagtgacc actatttacg tgacaaaatt tccattttaa ctagtattga
     8881 caacagagat taagaggagt tatagctatg gcatttgaaa gcctaaccca acgtttacag
     8941 gacgttttta agcacattcg tggtaaaaaa accttatctg aagccgatgt tcaggaagtg
     9001 accaaggaga ttcgtctagc cttattagag gcagatgttg cacttccagt tgttaagacc
     9061 tttatcaagc gtatacgtga gcgagctgtt ggccacgaaa ttattgatac ccttgatcca
     9121 acgcaacaaa tacttaaaat tgttaatgag gaattaactg gtatcttagg atcagaaacc
     9181 gcggagcttg ataaatcacc taaaatccct actgtcatca tgatggtggg cttgcaggga
     9241 gctggtaaaa cgacctttgc aggaaaatta gccaataagc tcatcaagga agaaaatgct
     9301 cgtccattga tgattgcagc agacatctat cgtccggctg ctattgacca gttgaaaacc
     9361 ttgggacagc aaataaatgt tcctgttttt gatatgggga caaatcattc agcagttgat
     9421 attgttgcca atggtttggc acaggcaaaa gagaaccgtc atgactatgt tttgattgat
     9481 acggcaggac ggttacaaat tgatgagaaa ctaatgggcg agcttcgtga ggttaaagca
     9541 ctagctaaac caaacgaaat ccttcttgtt gttgacagca tgatcggaca agaagctgcc
     9601 aacgttgcct atgaatttaa caatcagctc gatatcactg gagtagtgtt aacaaagatt
     9661 gacggtgata ctcgtggtgg tgcggccctt tctatacgtg aaataactgg taagccaatc
     9721 aaatttaccg gaactggtga aaaaatcacc gatattgaaa ccttccatcc agaccgtatg
     9781 tcaagtcgta tcttgggaat gggagacctt cttaccttga tcgaaaaagc aagtcaggaa
     9841 tatgatgaga aaaaatcatt agagcttgcc gcaaaaatgc gtgagaatac ctttgatttt
     9901 aatgacttta tcgagcaatt agaccaagtg caaaacatgg ggccaatgga agatctgtta
     9961 aaaatgattc caggtatggc aactaatcct gctctagcca atattaaggt tgacgacaag
    10021 caaattgctc gcaagcgtgc tatcgtttct tctatgacac ctgaggagcg tgagcagcca
    10081 gagcttttaa caccaagtcg ccgccgtcgc attgcagctg gatcaggtaa tagtttcgtt
    10141 gaagtcaaca aatttattaa agattttaac caagccaaag ccatgatgca gggtgtcatg
    10201 tcaggtgata tgactaaaat gatgaaacaa atgggaatca accctaataa cctccctaaa
    10261 aacatgccaa atatgccagg aggcatgcct gatatgtctg cccttgaagg aatgatgggg
    10321 caaggtggtt tacctgacat gtctgcattg ggtggtgata tggatatgag ccagctcttt
    10381 ggaggtggtc taaagggtaa gattggtcaa tttgccatga agcaggccat gaagcgtcaa
    10441 gctaataaga ttaaaaaggc caagaaaaaa cgaaaataga ctaaaagaat ggttgccttg
    10501 tattctgcct ctaatcgtta gatgctattc taatttggag tgcaggtcag tagcgaccat
    10561 cttttttata aatacaatca ctagatcttt ggttctaacc attaaacatg atatcatttc
    10621 actattagct gttagtgcct gtgctttaat tgctttctga tcttatatag caaattagcc
    10681 aagtgataaa aaggactgat tgctaggttg aattctccaa taaactcttc gatagttgga
    10741 ctgaaattgg acttaaatgc tgtcaatccg tccttgaagg agccatcaat gccgcccata
    10801 ttcgcccaag ctatatcatc atgataggca tccataaaga ctttaggata aagcaggtac
    10861 tgaggataaa actttttaaa gtcatcattc atgccagcat agagcatttc catcgtgttg
    10921 ccatatgaaa tcgataaaat gcccgcaatg acaacctcat ctggatattt atccaagaag
    10981 tccttgaatt ctgatagata acgctgaagc gattgctttt gatctgttag tctagccagt
    11041 cgcttttttt gatgcgcttg cgtttgagca agctcttgtt caacagcttt cagctgaagc
    11101 tcgtaattct tgagtttttc tggaagatta acctttgcta aatgcaaata agcattgtcg
    11161 ccataagtcg tcatcagctg tctaaaataa gcttcgtttc ttagagcaac tccttttctc
    11221 ttttcagtta aagagataag gtcagcaaat gtatggagat cagactgatt acctcgataa
    11281 gctatcacgc cacgttgcct agcatccttc atcaatcgct tggtatgctt aggaaaggac
    11341 gcttcaatat cagcattagt gtaacaattt gcttgaaaac gcggctgaat agtatcagat
    11401 agcttggttg ttgggcctgt ccaatgggca ccaaatcgct ttaaatgctt aataatggtc
    11461 agagccttgg aattatcagg tgctttctca ccaagctgat gctgctttag cagaatcata
    11521 ggatcaaatt taatcaaaag agctcttttt ttcttaccat atgccttcaa ggttttaatc
    11581 gtaaatgcca ctagatcagc attggtatag tccatcactg gacctcttgg aatataaatc
    11641 atcgtcatac caaacggcaa aggcttaatc agcaaggaca tagaagccac ctgattatct
    11701 ccctgaaaaa taccgatgcg ttcattttgc cactgatttt taacagctgc ccatgagctg
    11761 ctctgcaaga ggttaacctg ctggtgctgt ttgacaaatt ggtcatgctc ttgagctgaa
    11821 ataccgattt ttgaattaaa agctacattt atcatcatat ttcctcatct ttaagtatct
    11881 aaatatctga tcttgaaata gatctgcttc tacttaattt attcgaaaaa tagtttgaaa
    11941 aataattgct ttttttgatt ttcaatttga ttatttttag ctgctcaaat gaataatcga
    12001 tttcggttta aataagttta aaaaatagga ctaattccta atgaaatcag gaattagtcc
    12061 tactactttt atctatttat cagttaccca ttaggctgtc aatcaatcct ctaaagaaat
    12121 caataatttg ctgaaggatt ccctgtccag tctttaaggc ttcagtagca tcaaagttca
    12181 cgttgatatt tttaaaggta gatccggcct tttcaacaat actatccttt aaagcattca
    12241 gcgttttggt gaagttttca ttggaaatca cgccactatt tgagaggtta agcgcgaaat
    12301 tgataataag gttaatctga tcaggtgtta ctgccttggt taacccataa tgatctaagg
    12361 tttctgttac aatttggcgc accttttcct cattaacccc ttctccagcc tttgcgacag
    12421 cagctttaat atcagtaagc gcaacattta gcttatctgc atcatagcct gttttacctg
    12481 cattttcggt attgatatta gatagggttg atagctcctc ttgtgccagc ttcttgtttt
    12541 cctctgggac tttggcacca tttttttcga gtgaataata aataccggct aaagctgatt
    12601 ctccagtaac tgggattggt gcagctacag taatattggc atgctcaatg cccaaggtca
    12661 cagcggcgtt acgatacata tcttgcgtca ccttagtgat attttcaggt gttacaatag
    12721 ttaccttaag cgtttcttta gctcccagct tttgaatcct aactgaggaa taaagctgta
    12781 ggctcggatc atctgctaca ttcatgatac tagcataggc agttgtattt agggtgctta
    12841 atttgttatc agaagcacta ttgtagtgaa gcaaggccaa ggtttgctct ctttgctcag
    12901 cagacagtga atagcctaaa acgtaatcag gctgaacata ggtttcatca attacctgtt
    12961 gaacattatt agctgcagcg tgtactgttt gaagcataaa taccgaagcc aaagccatac
    13021 tggctgctat taatttcttt tgataagtca tttttctacc tcttttgtgt tataaatttt
    13081 cctttacgag aatcctccag aaaagacgat taaagccaaa gtatctaggt gcctagtaag
    13141 accgttttac ttagctctgc aaagggcaat attcctagtc tttttcaaaa tctaacgcct
    13201 ctattgtagc atttttacct caataagacg attaaaaagc tgaaacaaag catagctaga
    13261 atggccaagc actattttta caacaaaaaa actagtgcat aatggcagct tagatgtagc
    13321 tactatcact agtccaatga ttatcttatg cagcaaccag tctttatgat ctgaggtttt
    13381 cttgatggtt attgtccttt aaatagaaat aataatgatc atcagttttg atgacatagc
    13441 catttttaac ctcattaatc acgtcctttt gatcaaactg gtagtcctta ggcggtaata
    13501 actctgagga aaaaaggcta tcataaggca cctcaccatt gtaaaaatgg taatggtcac
    13561 catgagaggt aacaaaacca tcatccgaga tagacacaat aatttgctct gctgctatcc
    13621 cctcttcctt gctaacttca ttaggacttt tgtcagtctc tttctttaag gctttgcacc
    13681 ttttttccaa ttgatgagat gattttagct tcttgcctgt gctatcttgg gctttaaagt
    13741 cacaagcgga caaaggaaat aatagtaaga tagtgaataa cgataaataa gcttttttgg
    13801 tcatgtttca ctctccaata cacgatatag tgtttctaaa ttcattttta aatgctctag
    13861 ataagttttt tgatcagctg gaaccacctc aagcgggctt aggatatcaa ttgctacacc
    13921 gttactttga gccaaggttt tggctagctt atctgaagca ttttcttcga cgaaaatcgt
    13981 cttcacatca tattttttga taaagcggtc aatttgagct aattggcgag gactaggctc
    14041 ttgctcagga gatatccctg caattcccaa ttgctttaga tcaaatctct tagctaggta
    14101 ggaaaaggct gtatgctgtg tcacaaaggt tttcctacct agagattcaa acttttcctt
    14161 ataggtcttc actaattttt gagccttagc cttaaaacgc ttagcatttt gcaaataaac
    14221 tgccttgtga gcaggatctt tttgactcaa taaagctgca atctgctctg cctcttgact
    14281 agctaagata ggatcagtcc aagtgtgagg atcatacaag gcatcggtat tcattccttt
    14341 ttttatggtg aagtgctcca agccttgaac cttgtctaat gttagatgtg atgtcccctc
    14401 catgactgct aatccctttt tttccagctg tggtgccaaa tccgcagccc aagcttctaa
    14461 tatcttggaa tggtaaataa agacatctcc atcgtaaacc ttagcaacaa ctgtcggact
    14521 tggctcatac gagtgtatgc tagtgttttg ggcaatgacc tgaacatcat ttaaatcccc
    14581 gcaaatctcc tttgtcatag cataaatagg ataaaagctt gtttttatga ccaaaccggc
    14641 cttcctactg ctagagctct gatgacaggc tgatagaccc aaaagtactg ctaatagtcc
    14701 tactgcgaca attgttttct tgaatcctct aatcatatct actctcttaa ctagttaatg
    14761 acctaaaaag gataccatga tttaactgaa atgtcaatat tttatcattt tagcgcacga
    14821 cgtacacgca tgaagaaaat gcatgtaagc cttttttagc cccatgcatt ttttaatcta
    14881 tttctagcgt tttgacattg caatatcatc agtttgtcaa tttcaatgtg atgacttcat
    14941 cacattttgc taaaaaggcc atagtgatga taaaaaaccg ctaccagaaa gcgtaaatgt
    15001 cttcttgctt ttgtcgtgat tttagtgaac cgcctaccaa ctgaactgat gctggcttaa
    15061 ccatttcctg gccaccatca aaagcctgcc tctcaattaa caagcttact caaggaagag
    15121 gtgactgagc catgcatccg tcttagttat gactaacagc ttatcttggc atttcattca
    15181 tgtaattcca gtggcaggcc atcaggatca aaaaagaagg tcatcttctt accagtataa
    15241 tcatcatacc taagaggctc gacagcaatg cccttagcca ttaattgttc aatataagct
    15301 tcaataggct taacatgaaa agctaaatga cgaagcccac aggcctcttt gtcatattcg
    15361 ggcctaccga tacgcttagg cggtgcctga taagctggat cagtcttttt attgccaaaa
    15421 atctctaatt caatggctcc acattttaaa tccaatttgt aatcatgtct atcaggccgg
    15481 tgattttcac gaataatctc aaagccaagc ttattgacat aaaaatcctt agagacctca
    15541 taatccgaaa caatgatagc aatatgatga atagccttaa gctccatatg atttagttcc
    15601 tttattaaat aaaaaaagtg aaacaaagca atgccaagat tactttgttt cacccctcgt
    15661 agcgacccct cgcctagatt aggcttaggt tgacatctga ttgtaagagt gattaaaggc
    15721 cttcaaaaca tcgtcaggtg ctttgttaaa ctcatactcg tttttgattg ctcctttgac
    15781 aatgattcgc tctgttgcct cataatccgt acaggtgacc aaggttacct cctttagccc
    15841 tggtgtgtca ttgataacat ctattctctc aggtgtgacc gtaaagacgg cattgatctc
    15901 gtactcgtaa atacgctcct tatctgtaag gtaaatagac atcccttctt ttgctctttc
    15961 aagcggtgag aataacattt cagaagagcc tgttagtcca aaaatatgat gactggctaa
    16021 ggagtaattg ttttctcctc ccataacctg gtcctctttc atggtaccag caccgtatat
    16081 aagctctgtg ttgccaagcc ctttaaagat tggtaggtta ataccaagct ctggtatggc
    16141 aatacctcct attactggaa gctgctgggc gtccatttga gcctgtaaga cactttcggt
    16201 gctaactggc tgaactgctt gaaaatcaaa gcttgacttt gcttccttat tctttttaat
    16261 cgtctttttt gaaacctttg taacttgata tttattagaa ttccaagcaa tcagggtgtt
    16321 tctaatgggc ttgttaaata acaaggctaa gcctatgatt aacaataaga cgactagaat
    16381 acctctagca aaggacatct ttcttcgttt ttgtcttctc ctgtgggttc tttttgccat
    16441 tcatttactc cttgctagaa tttattggtg cttctgttaa agctgtatca gtctgagcga
    16501 ttgctgttgg atcgttgtct tcagcctgta ccaaggtaaa ggtaacaatc ttagaatctg
    16561 tatctagcct cataacctta acaccaagtg ttgaacggcc agtctgagaa atacttgaaa
    16621 cattggtacg aataatcaca cccttcgttg tgatcaccat aatatcctca ctgccatcaa
    16681 cagtcatcag gccagccaac tggccatttt ttgcggtgat attagctgtt ttgattcctt
    16741 ttccacctcg acccttagtt gggtattcgg ctgcactggt acgcttacca tagccatttt
    16801 cggtgatgac taagacctct tgcttgtcat tgatacgaga agctccgaca acccaatctt
    16861 cctcacgaag cttgacacca cgaacacccg tagcgctacg ccccatgcct cgaatggtag
    16921 cttcattaaa gcgaacagaa taacctgatc ttgttccaat gataatatct tcctgaccat
    16981 ttgtcaagag aacattaatc agctcatctc cttccttgag attaagggct cgtagaccat
    17041 tctgacgaat attgctaaac tctgatacct cagttcgttt gacaatccct tgctttgttg
    17101 taaagaagaa atatttatca agaatgtctt cttttttagc attgataatt gtttgaatgg
    17161 tttcaccatc atctagcttt agtagattga taacaggaag tccttttgca gcacgtccat
    17221 attctggaat ctcataggcc tttaagcgat agacgcgccc aaaattggta aagaaaagca
    17281 atgtgtcatg tgtacttgtt gagacaagct cacgaacaaa gtcatcgtca ttgacacctg
    17341 ttccctgtac accacgacca ccacgctttt gagatcgaaa ctcgtcttga gcaaggcgct
    17401 taatgtagcc attgtttgat agggtgatca aaacatcttc ttcctcgatc aaatcctcat
    17461 cttctaatga caatacctca ccaatcatca attctgtgcg gcgaggatta gcgtacttgc
    17521 gcttgatctc ctccatttct tccttgatga tggcttcgat acgctctggc cttgccaaaa
    17581 tatctgccaa atctgcaatc aaagccagta ggtcatcgta ttctgattga attttatcac
    17641 gttccaagcc ggtcaaacgg cgaagacgca tgtctaaaat agcctgactt tggcgttcag
    17701 acaagtcaaa acgagacatc aattctgctt gtgcgataat atctgtctcg ctattgcgga
    17761 taatggcaat aacctcatct agatggtcaa gagcgataag taagccctct aaaatgtgtg
    17821 ccctagcttc tgccttgtcc ttgtcaaatt gagtcctgcg tgtaatgacg tccttttgat
    17881 gtagaatata attatcaata atctgtctca gtgacaagat tttaggaatc ccgccttcaa
    17941 tggctagcat attgaagcta aagtttgtct ggagacttgt caatttgaat aggttattta
    18001 aaatcacatt agcagatgca tcgcgacgga cttcaatgac aaatcgtacc ccttgtcggc
    18061 ttgattcgtc acgaacagct gtaatgccct caatacgctt ttcttgggct aagcgaacaa
    18121 tatgctcatg gacctttgtt ttattaatgc cataagggaa ttctgtgacg acaatccgct
    18181 cccgtcctgt actagtggtt tcaatctcgg tgcgtgaacg caaaacgatt gatcccttac
    18241 cagtctcata agccttatga attcctgaac gtcccatcac caaggcacct gtaggaaaat
    18301 ccggccctgg aagaacctcc attaaatctc tggtagtgca gtcaggattt tccatgacca
    18361 tcttaacagc gtctatggcc tcagctaaat tatgaggtgg aatattggta gccataccaa
    18421 ctgcgattcc ggtggcacca ttgaccaata aattggggaa gcgagccggt aagactaagg
    18481 gttctctttc attaccatcg tagttatcct gaaagtcaac agtattttta ttaatatcct
    18541 ttaagagctc tagcgcgatt ttgctcatac gagcctcagt ataacgctga gccgcagcac
    18601 cgtcaccgtc catagaacca aagtttccat gaccatcgac aagcatgtga cgatagctcc
    18661 accactgggc catacggacc atcgcttcat agatggacga atccccatgt gggtggtact
    18721 tacccatgac atcaccggta atacgagcag attttttatg tggcttatca ggtgtgacgc
    18781 ctagctcatt catgccataa aggatacgac gatgaacagg ctttaagcca tctcgtacat
    18841 ctggaagtgc tcttgctaca ataacgctca tagcataatc aatgaaactc gttttcatct
    18901 cacttgtcag attgacgtca actaaatgtt tatcttgcat ttaaggaatg ctccttttct
    18961 agtcaatact cttttaatta taccataaaa tccttatttt ttctgattgg aaacgctgtc
    19021 cgaaaacaat tttcataatt tggtcgaata tcatgacaaa gacattaaaa tgtgttaaaa
    19081 taagatcgta tgagcaattt gctctaacta aaatgaagga gatgtttaga aatgactgca
    19141 actaaacaac ataaaaaagt catcttggtt ggcgatggtg ctgtaggctc ttcttatgcc
    19201 tttgcactag taacccaaaa tattgcccaa gagcttggta ttattgatat ttttaaagaa
    19261 aaaactcaag gagatgctga ggatttaagc catgcgcttg cctttacctc ccctaaaaag
    19321 atctatgctg ctgattatgc tgactgtcac gatgctgacc tagttgtttt aacagctggc
    19381 gctcctcaaa agccaggtga gactcgtctt gaccttgttg agaaaaatct acgtattaat
    19441 aaagaagtgg ttactcaaat tgtggcctca ggctttaagg gaattttcct tgttgctgct
    19501 aatccggtgg atattttgac ctattcaacc tggaaattct caggtttccc taaggaacgc
    19561 gttatcggtt ctggaacatc acttgactca gcacgcttcc gtcaggcact tgctgccaaa
    19621 attggtgtag acgcacgttc tgttcatgcc tacatcatgg gtgagcatgg agattcagaa
    19681 tttgctgttt ggtcacatgc taatgttgca ggggttggat tgtacgactg gcttcaagct
    19741 aatcgtgacg ttgatgaaca aggcttggta gacctcttta tctctgtacg tgacgcagct
    19801 tactctatca tcaataaaaa gggtgctacc ttctatggta ttgcagtcgc cctagcacgt
    19861 attacaaaag ctatccttga tgatgaaaat gcagttcttc cactttctgt tttccaagaa
    19921 ggccaatacg aaggcgttga ggattgctat atcggtcagc ctgctattgt tggtgcctat
    19981 ggtattgttc gtccagtcaa tatcccattg aatgacgctg agcttcaaaa aatgcaagct
    20041 tcagcaaacc aattgaagac tattatcgac gaagccttct ctaaagaaga gtttgcgtct
    20101 gctgctaaaa actaattaaa aaatgaatgt gttagatctt gctctaacgt tttggaatca
    20161 ctacaaaaag cctaatccaa tcggataggc ttttttcatg cgtctaacag cgaggtgcaa
    20221 gacaaagcac gctttcatta agcatcgtgt gtgctatgct tatagtctta agtcacaaaa
    20281 aagacaacca gctttatgag ctggctgctt attagcttgt tattcagcac caagtgctgc
    20341 cattgtaatg tagttatatg gcttgttaaa gtgcggtaag aagaaaatat cagtcaaagc
    20401 taatttctca atggtcactc cttcttggat agcaagtgag aacatatgaa ttcccattga
    20461 aatatcttca tgtgaggcca tttgagcacc tagaatacga cgtgattctt tatcgtagac
    20521 aatcttaatg gttacttgga agttaccatg ctcgataaat tctggttttt gattgtcagt
    20581 gtattctgtt actgctgcat caaagccaag gcattttgct ttctcaagag ttaagccagt
    20641 tgataccatg tgcaagccgt agatagagat accatttgat ccctgcacac caataccctc
    20701 aagagctgtg ccacaagcgt tatgagctgc gacaatccct gtacgaacag catttgaagc
    20761 aagggcaata taattggtat cgcgagttgc gttgtcatag atggttgcac aatcaccgat
    20821 tgcataaatc cctggaatag atgtttcttg gtgtttgtta acaaggaagg caccattacg
    20881 gaaaagctca atcttgccag caccaagagc tgtatttgga cggaagccaa ctgcaaggat
    20941 aaccatatca acatcatatt cattcttatc agtgattagc ttttcaacct tgccatcacc
    21001 agcaacctct ttgacagttt ccccaaaggc caactgaata ccatgctctt ctaggttttt
    21061 agacatgaca tctgtcaaat cacgatcata gtagcctgct agacaagtat ccgcaacatc
    21121 aatcagaata acctctttgc ccttacgttg gaaggcttct gcaagctcta caccaatgta
    21181 gcctgcacca acgactgcaa cgcgcttaat gtctttgttt tctaatttcg aaatgacatc
    21241 tgctgaattt tggtacaatt taacgaattg aagattttca agtgttgctt caaactctaa
    21301 tgagccctct ttgatttctg cacctttaat tggtggcaag ataggctgtg aaccagttgc
    21361 aaaaattaat ttgtcatatg actcaacatg ctctttgcca tcaacaaggg ctgtcactgt
    21421 tttagcatcg tagtcaatag attgaactgg tgattccatg taaaccttag caccaaggga
    21481 ctctagctct tccttatttg agtagaataa gccctctggg ccagaaattt gttcgccaat
    21541 ccaaagtgcc ataccacagc ctaagaatga aatatttgag ttttggtcaa atacaacaat
    21601 ctcattagca tcaccatagt ttgttaacat agtcttgata catgccgtac ctgcgtggtt
    21661 tgcaccgata acaacgattt tactcatatg attatgttcc tcatttcaca atttatatta
    21721 ggtctctatt ataacacagg gaaaaagcgc ttccaactaa aatgctcatt tttcttgctt
    21781 ttttataccg ttttttagtc aataaataag acagcctatc atttgttgaa gggtcgtaca
    21841 aagaccggtt tgcttcagtt aagtcaagac gacattctta ttcaactatt ttcccaaatt
    21901 cattacatga ttaagaccat tttttgtcgt taacttctaa aaaagactca taagctcaat
    21961 caggtaaaga ttgacatgta cctcttgagc ataataaata ttgccgccgt tgcaataaag
    22021 ctttccacca gagaggaggg ctaaggggtg gtaataaaaa taggtttttc cagtagtatt
    22081 tcctaggctg ggtgcaacga cagttctaga atagttagtg gctagttcaa ttgtatgctg
    22141 accgccattt ttagcaacgt aatcaatata ggcggttcca aaattgtaag cttgaacagc
    22201 tgtccaaggg tctacgccgg ctttttctgc taaagctaaa ttgtgagata gcaatctgac
    22261 accatactca atgctagatt gactatcggt gatcgaatcc cttatgccag agctgctttc
    22321 gcttgactgc ataacgtcag cttctcctcc cttagtttcc gtgtatatca tggctagtac
    22381 cagatcgacg tctgctttgt taccgttttc tgctaaaata cgctctactg ttggcttgta
    22441 ttgtaggact ctgtgcacat tcttatgaat ggtaactgct tcgtacaggc aaaaaatgag
    22501 gacggctaat cctaagatac gctttaacac tctaaacatt tagttatttt tgatatcctc
    22561 tatatttttt atcaatatgg aataggttcc gttgtcattc aagataaact ctactgactc
    22621 agcatcttga taaactgcat tagggacaag aagctcaatt ccatttgaca gcgacagctt
    22681 ttgcgtctct agctttttta gctgtctaga atgatcaata tcactgacct gaattggttc
    22741 gggaatcatt tccttgacct gatccacaaa ggttaacctt gcagtcaggt tctggtcaaa
    22801 taattgatct gctagctttt ctggagatag agctgtttct tcttctagat ttttagccag
    22861 tgctactttc atctttgatt gaaaagcaaa gtcatcttgg ttaaaattct cggcaacctt
    22921 ttgagcggtc tgctcaagca tttgaataga ttttttgaca gattgctcag gtgttacctt
    22981 tagcagcttc tcagaaaagt aatgagcaaa gcttccattg tgcttcatgc gtttttcgat
    23041 taagtagtaa tagcctgttt gacggttaat gaccaaggct tcatcaggtg cctgagtagg
    23101 gcttggcaaa ttattttgcg tgatcgtaat aggattttca tgatcgtctg atagatgggc
    23161 aaaatgctct tttagggcaa tgcgtaaaaa ggccagataa ggcactcctt ccttatcaaa
    23221 ctgaataaaa accaaatcgt ttgtcttttg atgttcagaa gcgacaaatt cttccttcca
    23281 aagcttggca attgttactg atgtttccaa aagctctgta ccgattgtgg taaaaaaagc
    23341 atgatcagct tctaattgcc cacgtttagc gtcgtcagaa aaaaccttgg ctaatttttt
    23401 gcgaaaatac tcatcaattc ttggtgttat agctactaaa gcatctgata agatcagctc
    23461 ggtatcgttt ggtgtgaatt ggtggatcac aattcctttt atataaatat ctagcattgt
    23521 tagttcttct tgtataatgg gaaggcgtca gtcaatcggc gaacctcata acggacctct
    23581 tcaaggattt caggctgctg gtggttaacc aaggccttga taattaaatg agcaatagtc
    23641 ctactttcgt ctactcccat tccacgactg gtaatggcag cgcagcctat gcgaatgcct
    23701 gatgttttaa agggagatag ggtctcaaaa ggaatagcat ttttgttaag ggtaatatta
    23761 acctcatcaa gcaaggcttg agcaagcttg ccattttcaa tcaccttagt cacatcaaca
    23821 aggaaaagat ggttatctgt accgcctgag atcagacgaa aacgatcatc cttggcaaaa
    23881 acctctgcca ttgctgctgt atttgctata acagcccttg catagtctgt aaaggcagga
    23941 tcaagcgcct ccttaaacgc aacagccttc gctgctatga catgctccaa aggcccaccc
    24001 tgtagaccag ggaaaatagc tgcattcatt ttccttgaaa ttgcttcatc atttgtcaaa
    24061 agcaggccac cacgaggacc acgaagggtt ttatgagtgg ttgaggtcac aatatgagca
    24121 taaggtactg gattttgatg cagacctgct gcaaccaagc ctgcaatgtg tgccatatcc
    24181 accatcaaat aggatcccac ctggtctgca ataaaacgaa attgctcaaa atcaatctgc
    24241 cgagaatagg ctgaggcacc tgcaacaatc aacttaggct gaacagcctt agcttgcttt
    24301 aggatagctg cgtagtccag cttttcagtt tccttatcga cagtgtagcc gacaaattga
    24361 taggtttttc cagaaaaatt gacaggtgag ccatgtgtca agtgacctcc agctgccaaa
    24421 tccataccaa gcacagtgtc accagcatta atcagtgcca tataagcagc agcattggcc
    24481 tgactaccag aatgaggctg aacgttggca taggctgcac caaagagctt tttggcacgc
    24541 tcaatagcaa ggctttcaac aatatcaaca tactctgtgc cgccataata acgcttgctt
    24601 ggatagccct cagcgtattt gttggtcaag acagagcctt gtgcttgcat aacagccttt
    24661 gagaccatat tttcagaagc aattagctca atattatgct cttgcctgtc ctcctcggcc
    24721 tgaatagcct cccaaagctc ctgatcatag tctttgtagt tctcgttgtt aaacatcatt
    24781 attgtctcct ctataatagc ttcataaatc gtaattgtgt cttatcatct acatagctca
    24841 gcttacggta aaaggcatgt gcctcggtcc tgtgactagc agaattaagc cgaataaagc
    24901 ttactttctc ctgcttagcc ttctcctcta aagcagctag taagcgacga ccgatacctc
    24961 taccttgatg gtccagcctc actgctaagg ccaaaatatt aaagcctttt tccgagtaaa
    25021 gcgactcgta gcattcagca tgcagatagc ctaagagcag attggtctta gtatcagcat
    25081 agcccagcaa ataatgatgc ttatcggatc ttagtttttc caattggctt tttgtcaatt
    25141 caagagaaac cttgtacccc aaggattgat cattaatgtc acaaatagct tgacaatctg
    25201 tttgatctag tggtcttagc atagccttac ctcctctaaa atggcagctc tggaacctta
    25261 gctaataatt gctccttagt aatagcacct tgtcgtaaaa tactgacctt aggtgacgat
    25321 aaatccaaaa tagtagaatc cttccctgtc aaataggcat catcagcata accatcaacc
    25381 tttccatcaa atgccttgac aatgtcatta aagcattttc cactctttga gcctgacagg
    25441 ttagcagatg gcccaatcaa gggacccgtt gctctgataa ttttagctgt gagagggtga
    25501 ctgggtagtc gaaagccaac tgtttttagc ccagaattaa tccaataggg tgtctgggca
    25561 ttggctttta ggataatcgt aagtggacca ggtaaaaaag cctcgtacag cttgttaaga
    25621 taggcaggct gctgcttaga aaaagccaaa atactctcaa aatcagccac attaaggttc
    25681 atagccttgt cgcgaggcct ttttttgaga cgataaacag cattaacagc ctcttcattt
    25741 aaggcctgag caaaaagacc ataaactgtc tcagttggta aaataagagc tccaccagcc
    25801 ttaattgtct ctatcaaatg tgttatcatc aacaaccacc attctttctt tacccagcat
    25861 atccttaagc actctgatac gcttttgagg gaaacgcttg gataagagcc tttttaagcc
    25921 ttctccctgc ttgtagccta tttcaaaata gagcttacca cttgtcgtca gataagcact
    25981 agcttgttcg ataatgcgtc ggtaaataga aaagccattt tctgcagcaa ataaggccaa
    26041 atgcggctca gattgataaa cattcaagcc aacctcgtcc ttatcctcat aggcaatata
    26101 gggagggtta gaaacaatga tgtcaaactg ccctgatagc ttgctaaaaa ggtctgactg
    26161 ctcaaaggct atctctacat gatgatctaa agcgtttgag taagcaaggc tcaaggcatc
    26221 agctgaaata tcagaggctg tgacctgcca gttaggtctt gcttttttta aagcaattgc
    26281 aatagcacca ctgcctgttc caatgtctaa aacggatttg cgagtagcgt cattttcctt
    26341 caagataagc tcaactaatt cttccgtctc tggtcttggg attagcacgc gcgaatccac
    26401 tgcaagcacc agatctctaa aataagccct gcctgtgata tattgtggcg atacatgctg
    26461 gctaagcgct aaaaaaatcc gctctaataa ggcttgatcc tctgaagtga cctcttgatt
    26521 ttgatgaagc aaaaagtcaa ggcttgtcca ctgctttaat tctttaaaaa cataggcgag
    26581 gttttcacga tcctcaccta tgttttctag cctgtcttcg taggctctta gttgcttagc
    26641 atagttcatt ggttatttag cgattctaat ttctgagttt gatcatatag cactaaagcg
    26701 tcaacaatct cgtctaactt tccagacaaa atggtgtcta atttttgcag ggttagaccg
    26761 atacggtgat ctgtcacacg attttgtggg aaattatagg tccgaatccg ttcagaacga
    26821 tcacccgtac cgatagttga tttacgctct gcgtcctgct cgtcctgtgc gatctgtgca
    26881 aaatgatctg ctacacgtgc ccgaataatc ttcatagcct tgtcacgatt cttttgctgc
    26941 gttctttcct cttgcatctc aaccttgatg tttgttggga gatggacgat acgaacagcg
    27001 gttgccacct tgttgacatt ttgtccgcca gcaccagaag catggtaaat atcaatacga
    27061 aggtcctttg gatcaatgtc gtactcaact tcttctacct ctggcatgac taagacagtc
    27121 gcagttgaag tatgcacgcg cccttggctt tctgttacag gaacacgctg tacgcgatga
    27181 gcacctgatt cgtattttag cttggaataa acagattgtc ctgaaaccat agcaacaacc
    27241 tctttaatcc ctccaacacc attataggaa gcctccatta cctcaaagcg ccagccttgg
    27301 ctttcggcaa atttttggta catggctaag agatcaccgg caaatagagc agcctcatca
    27361 ccacctgcgg caccacgaat ttccaagata atatttttat catcatttgg atctttggga
    27421 agcagcaaaa gctttaactt gtcctcatag gcttccttgg cagacttggc ctcttttagc
    27481 tcctccttgg ccatctcttc aatgtcagga tcgccgccgg cttccttaat catctcctca
    27541 gcgtcatcaa tggattggat aatagcctta tactgacgat aagctgctac tgtttctcgt
    27601 gtgctagcct cttcctttga cagagccata aaacgtttgg tgtcagaaac aacctccgga
    27661 tcacttaata attcgcctaa ttcttcataa cggtcctcaa cggcctgtaa ttgatcataa
    27721 atattcatta gggggtattc tctcctcttt ttacttgttt tagttgttat tagattggtg
    27781 ggtgaaaata atgcttgcga caaactggaa tataggtctc attgccacca atttgaatct
    27841 gtgctccctc ataaacgggc ttaccatgtt ctgttcgcaa taccatagtt gcttttttgc
    27901 tgcaatattg acagatggtt tttatctcat caatcttatc agctaacagt aacaggtatt
    27961 tggagccttc aaacaattca ttttgaaaat cattttttaa gccaaaggcc atcactggaa
    28021 catttagctc atcaaccaca cgtgctaaat catagacatt ttgcttgctt aaaaattgac
    28081 attcgtcaat caagacgcaa tagggcttct cctgcaattc agcaataaat gcaaaaatat
    28141 ccatatcatt cgaaattggt acagcctcac gacgcatgcc aatccgacta gaaacaatgc
    28201 caaagccatc acgtgtgtct agcgcacttg tcataatcac aacaggcttc ccctgttctt
    28261 cataattgtg tgctaccttc aagatttcaa tggtctttcc tgaattcatt gttccatatt
    28321 tgtaatataa ttgagccaaa atggagattc ctaccttctt cttttgtcct acttattcta
    28381 tcatatttgt ccctatttgg cgattgcctt atctgaaaat cttattttca caacagctaa
    28441 atcctgtgct gttgagctaa ggttaggctt tttgaagctg acatgctaca atagaggtat
    28501 cattaaaaaa aggagattga ctattatgcc atttgtaacg attgacctgt ttgaggggcg
    28561 tagccaagaa caaaaaattg ccctagcgcg tgaggtgaca gaggttgttt ctcgtatcgc
    28621 acaggctcca aaagaagcga ttcatgttgt aatcaatgac atgcctgagg ggacctattt
    28681 cccgcatggt gagatgaaaa ccaaagccta atgcctaagt cccacttatc taggtgggct
    28741 tttcctattt gaaaaggagg gcctgatgat agctactgat cagatcaaga tgatgggaac
    28801 aatcattgat atttgcattg actcatcaaa agcaaagcag caagcagcta ctatccgaga
    28861 gctactaacc ctttacaatc accgtttttc ggccagtgac gacagctctg aattaatggc
    28921 aatcaaccat atggcaggta ttcagccagt gcgtgtgcat tcagatttgt ttgacttaat
    28981 ctcaatcgga aaagagcata gcttggctta tccaagcaac cttaatatca cacttggtcc
    29041 tttagtgcaa agctggcgca tcggcttttc agacgctaag cttccagatg aagcaactat
    29101 tgatcgcaga ctaagactaa ccaatcctaa tcatatcatc
//
LOCUS       DARYNN010000028        28033 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.028, whole genome shotgun sequence.
ACCESSION   DARYNN010000028 DARYNN010000000
VERSION     DARYNN010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28033)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28033)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28033
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.028"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(298..813)
                     /locus_tag="TVB59_001170"
     CDS             complement(298..813)
                     /locus_tag="TVB59_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEL1010069.1"
                     /translation="MIKKWKQLLSAKKADALSDRILSVAKGQLVPITSVSDPVFSERL
                     MGDGFAIIPQEGAIYAPVTGRVMTVFPTKHAYGIVTPAGLEVLIHIGVDTVELGEAAF
                     SSDIVAGQEVVAGQLLAQVSLPVLEAAQKDSTVMVVFTNSQDIADMRLADAGAVAARA
                     EVGQVRLKATL"
     gene            complement(815..2326)
                     /locus_tag="TVB59_001171"
     CDS             complement(815..2326)
                     /locus_tag="TVB59_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEL1010070.1"
                     /translation="MDFKKFSKLGQAFMLPISILPVAGLLLGIGGALSNSNAIAQFPI
                     LNQAWLQAIFTIMSTAGNAVFANIALIFAIGVAVGLANGDKGTAGLSGAVAYLVFTAT
                     ISGYLTLFSAKDAQIDTGVLGALTVGLVVVSLHNKYRKIELPAFLGFFGGSRFIPIVS
                     SLAAIVIGSVFYVIWPPIQNLLVVFGEKIADMGSIGTFLYGFFLRLTGAVGLHHTIYP
                     MFWYTSLGGSEVVAGETIQGAQNIFFAQLADANHTDLFTYGTRFFAGRFATMMFGLPA
                     ACLAMYHAIPKANRKKVGSFYSSSALTSLLTGITEPIEFAFLFVAPWLYVVHAFLDGC
                     SFLVADLLKIRIGNSFSGGLIDFLIFGVFQGNDHTNWLLVIPVGIVWFMVYYFVFKFF
                     VSKFQVAVPGMVAQVEAEGQAETTNTQSSSLREVSLAIIEALGGQANIEDVTACATRL
                     RVSLSDSSLVNKNVLTSLGATAVLDVKNGIQAIYGGKAILYSQEINQLLGRED"
     gene            complement(2316..3041)
                     /locus_tag="TVB59_001172"
     CDS             complement(2316..3041)
                     /locus_tag="TVB59_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEL1010071.1"
                     /translation="MLEKPSKAELLTALKDGLIVSCQALPGEPLYSEAGGIMPLMAKA
                     AEEAGAVGIRANGVRDIKEIQAVTDLPIIGIIKKEYPPQAPFITPTMAEVDALAALDV
                     AVIALDCTQRERHDGLAIADFIRSIRKKYPEQLFMADISTLEEGLVAYEAGIDFVGTT
                     LSGYTPYSRQGTGPDMELISALCDAGVSVIAEGKIHSPEEARAVQALGVAGIVVGGAI
                     TRPKEIAERFVAALKKEEKSHGF"
     gene            complement(3570..3992)
                     /locus_tag="TVB59_001173"
                     /pseudo
     CDS             complement(3570..3992)
                     /locus_tag="TVB59_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678587.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(4136..4642)
                     /locus_tag="TVB59_001174"
     CDS             complement(4136..4642)
                     /locus_tag="TVB59_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010072.1"
                     /translation="MTQTFFNNDVDERRRQLYLDARSKGHLEKCFRGDSGFKINAKDS
                     YFQSITDINVLIERCLYPLYDLGDSIIPHETERILSQFSTSKNVVELYQVVSYIFYQK
                     NNKLLKKNFSFYIDFNPMIPDLVFSVKRLSPENIVTDDEKAMVGFIKNMFQKIPQVQS
                     YLEAQNCK"
     gene            complement(4644..5570)
                     /locus_tag="TVB59_001175"
     CDS             complement(4644..5570)
                     /locus_tag="TVB59_001175"
                     /inference="COORDINATES: protein motif:HMM:NF019104.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010073.1"
                     /translation="MNEPIAARVTKPTYNRQQLLKNLENSRLATESSRFKSYVAREKL
                     INTLRKQNADLNLITFREKAIEIFNRDLKGNSWVSIRQADEFVETLDDYAQLSVDNGA
                     VSTKADFYKMYSNKNYIYLDGFIKNIKQLYIKTGASSIVNGQDLYNAIEQYGTIGRGK
                     SGNFATSMAEDIALLYDSSGNLVSSGMIEAIKGVDEGKYLSGAFQYEYSPQFVKSFDQ
                     IGEVRTVTGKTPGSSLLNIPGAKTWAGKNMALSQSELMMPSIDTSNLKLEDVLLSMES
                     TGIYTLNNPTIVLKDGTKKIVEGQFIIRKLGN"
     gene            complement(5712..6134)
                     /locus_tag="TVB59_001176"
     CDS             complement(5712..6134)
                     /locus_tag="TVB59_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010074.1"
                     /translation="MEHSQLEWEDVSQYEEVKGYGQQVWKRQGTYYLVTNEGGIAEQR
                     VVYELPYDLFELLEQGKRNLGEIAFKLRYDCWPPTEEEKIASDKAFLQRSPIALIADP
                     TSWELFTQEELRKLIPIAEQKWIDWKGKLPDDYVSPLK"
     gene            complement(6457..6717)
                     /locus_tag="TVB59_001177"
     CDS             complement(6457..6717)
                     /locus_tag="TVB59_001177"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010075.1"
                     /translation="MDNNNCFQYTQRLRELIELEYPKQKNYSGILRDLYVLTNDIDNN
                     RIVGNINFSSLARQFVDDTTQYDSPILKTLKDLEVCLNRKRR"
     gene            complement(6732..8540)
                     /locus_tag="TVB59_001178"
     CDS             complement(6732..8540)
                     /locus_tag="TVB59_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010076.1"
                     /translation="MSYNIKYDEITSLQQSTQTTISAWGDGITSIQTALSALIGDSRL
                     QGQTASSIKSYLSEVHGTLLQTLQSLMNDYSASLLLYKDGYYQIDSNSHAQLPGQVFK
                     TLQSELRLSQAHLKDQLELLQNTRAKLSDLVHYSGVSHAKTVVDYSELITDIHRLDEA
                     IIQYESNHASQDLAAFKELLASTKALIAEYSSKPKRAGSYQVGDIGQLNTIKRFATAY
                     QGVARHLETNAKRLQAAQERDHARFEAVAAEDRAKQGWIDLALSLVTIAVGVAAIVMT
                     AGAATPLVVGAFVVGSGTVAYGASNLYEAGHNIYLGSVGDGLTVATNPLRDTLFMGND
                     RLYHQIGGLFTTASAALILIGQTKSVAKGLTEFTIGEVGGFIGGQASYHGTKLLGGSE
                     QDAQRATLVGNILAGYAASSAARRFSLNEPIAARVTKPTYNHQQLLKNLENSRLARES
                     SNFGGYIKKESVTKYPTQIDSKVTVGAKENLPGWIADSFTDSHYRTVITGEEITLYRT
                     FGGASDAGGGFVTTVPATNRIQAKIDTALLPEWKNTRQYEAVIKIPKGSQLNIGKVAP
                     QTVKSSGTTLIGGGDQVLLPNRWPLEWIQEIRIVPN"
     gene            complement(9181..10080)
                     /locus_tag="TVB59_001179"
     CDS             complement(9181..10080)
                     /locus_tag="TVB59_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEL1010077.1"
                     /translation="MVLFTGKTVEEAIEKGLQELGLSRLKAHIKVISKEKKGFLGFGK
                     KPAQVDIEGINEKTVYKADKKAVRSVPEEINRQNAPVINPDEVELEEMKAVRSQDRRA
                     AESDAHQPTGPLSTAQSAPTQSKAQPVSSAAGASQLDPAAADMSKDIELAAQEISDYV
                     TKIIYEMDIEASIERTNNRRQINLQIETPEAGRVIGYHGKVLKSLQLLAQNFLHDRYS
                     KNFSVSLNVHDYVEHRTETLIDFTKKVSKRVLESGQDYTMDPMSNSERKIVHKTVSAI
                     DGVESYSEGNDPNRYVVVSLIHD"
     gene            complement(10092..10901)
                     /locus_tag="TVB59_001180"
     CDS             complement(10092..10901)
                     /locus_tag="TVB59_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002267318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEL1010078.1"
                     /translation="MKKRVKTAALVPLVLLLVACGRGEVTAQSSSSWEQLVYFFAKAI
                     QWLSFDGSTGIGIILFTIMIRLLLLPLFNMQIKSGQKMQDIQPELKALQKKYAAKDTA
                     TRMKLAEESQALYKKYGVNPYMSLLPLLIQMPVMFALFQSLTRVAFLREGTFLWVELA
                     RHDHLFILPILAAVFTFLSTWLTNLAAREKTAMITIMTYVMPVFIFFMGFNLASGVVL
                     YWAVSNAFQVVQLLLFNNPFKVIAERQRLADEEKERRAKERRARKRAMKRK"
     gene            complement(10885..11244)
                     /gene="rnpA"
                     /locus_tag="TVB59_001181"
     CDS             complement(10885..11244)
                     /gene="rnpA"
                     /locus_tag="TVB59_001181"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEL1010079.1"
                     /translation="MKKSYRVKREKDFQAIFKLGQSMANRKFVIYHLKGEHKHFRAGI
                     SVGKKLGNAVTRNAVKRKIRHVLMELGDHLKSEDFVVIARRGAEELDYQAVKQNLHHV
                     LKLAKLLEEGFEIEKKS"
     gene            complement(11736..12476)
                     /locus_tag="TVB59_001182"
     CDS             complement(11736..12476)
                     /locus_tag="TVB59_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1010080.1"
                     /translation="MLNIFILEDNLIQQSRIEAIVASILEEGRIPHNQLEVFSNPQKL
                     FDSIQERGDHQLYFLDIEIGDKSRSGLELASDIRQKDPNAVLVFVTTHSEFAPISFRY
                     KVSALDFIDKAVDSQQFKERIEECIRYTYEMMSSRQVEEMFLFETPQTRLKLPYKDIL
                     YFATATTPHKVCLWTQTERLEFYGNLSEIHAVAPKLFLCHRSYLVNLDNVVRIDKAKQ
                     LVYFENGDSCMVSRLRMKQLFEKWKSFR"
     gene            complement(12480..13778)
                     /locus_tag="TVB59_001183"
     CDS             complement(12480..13778)
                     /locus_tag="TVB59_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HEL1010081.1"
                     /translation="MLGMSFFYALIFVNSWVIFSTFSGIKLAVRSLLLVGACFVVANL
                     LLDHVLLVDQLVFVAVSVGFAPHKKASEHLFNGLFAIMIVELLFRIIGSFLLPAVLGY
                     SIHQINNDIGLLMVCHALVLPAFYLFSYIFSVDLTLIKFISEDKLKKWVFWMNAALLF
                     YYVMVHCMINIQGDFFKIYFRYRSVMIFLYLMLLIWVIVKLDRFAKDQLSQRLALAQK
                     ERVAYLEKHNQYIERLCREIRAIKHDSENILISLKDSIDSGDIAAISKVYQTVIQESA
                     SSIRQLTPELSALDNVQDSVIRSLLHAKLLEAKLQGIAVYIDIPETLASSSVRLLDVI
                     VLFKVVIDNAILSAKGSSRPFLSIAYFNQDGKRFFIIENSTRLKRVDIAKQFDASRLE
                     LGSHAHKRLLQFSAVLERYPHITFSTKSDHYRLRQLLEMR"
     gene            complement(13790..15136)
                     /locus_tag="TVB59_001184"
     CDS             complement(13790..15136)
                     /locus_tag="TVB59_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEL1010082.1"
                     /translation="MTDIYYLFLLLSLMIYYVTEISIFSFLSDIKLALWKQIFVLTAA
                     LFLNQFALLPPLIIDPLLLLAVLALEKRPCFSLKALFLAFVPGVFVDLLSRFILAIVL
                     PYIFSVNGSYVRHLVLDFIAYVMIFPSFALINYFVGKDYKQIVKADRFDKASSFYSLF
                     LLFSLAYYIDLFMILGFTDPFLDLKSPIMMSTSYKVLFLIFTLLLIYLLSYFNHQSKE
                     FLKQELKKEQQAYIANLETYGKHLEKLYKGVKVFQLVYLKRLERLGQAIDSGSVSDVQ
                     TVYAQTVDEATDYWDDKHYNISKLSKISVSSIKSLLSSKIIKAEKAGIALSLEVPDRI
                     RDSYISELDLLLLVSIFCDNAIEAALETAQPAVAIAYFLSDDQQIFTVTNTTKDERVM
                     ISRIFEEGYSSKGSGRGIGLSNAKRILQKYPELSLRTRSHDYQFSQTLIMPKIEKE"
     gene            complement(15581..17026)
                     /locus_tag="TVB59_001185"
     CDS             complement(15581..17026)
                     /locus_tag="TVB59_001185"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEL1010083.1"
                     /translation="MSKPIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGDFIIRIE
                     DTDRKRHVEDGERSQLENLKWLGIDWDESPETHERYRQSERLALYQQYIDQLLAEGKA
                     YKSYVTEEELAAERERQEAAGETPRYVNEYLGMSAYEKAAYIAEREAAGIVPTVRLAV
                     NEAGVYKWTDMVKGDIVFEGGNVGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPVFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYM
                     PEAVFNFIALLGWNPGGEAEIFSREQLIALFDEIRLSKSPAAFDQKKMDWMSNEYFKH
                     ADLGAVYALCKPFLEAAGRLTEKAEKLVELYQPQLSSADEIVPLTDLFFSDFPELTAK
                     EKEVMAAETVPTVLKAFKEKLEAMSDEDFKPENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPNTIYLLGREQSIEHIANML"
     gene            complement(17628..18341)
                     /locus_tag="TVB59_001186"
     CDS             complement(17628..18341)
                     /locus_tag="TVB59_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00266 family protein"
                     /protein_id="HEL1010084.1"
                     /translation="MAYNRMTYTIDSSMQFPLVEIDLDMGESVFLQKGSMVYHTPSIS
                     LNTKLNGRGSGLGKLVGAIGRSMVSGESMFITQAIANDVSGKLALAPSMPGQVIALEL
                     GVDQYRLNDGAFLALDGSAHYTMKRQKLGKALFSGQGGFFVMSTQGEGTLLVNAFGSI
                     KKITLHGDSMTIDNSHVVAWSQDLDYDIHLENGFMQSIGTGEGVVNTFSGYGDVYVQS
                     LNLQQFAGVLQSYIVTGGH"
     gene            complement(18469..18975)
                     /locus_tag="TVB59_001187"
     CDS             complement(18469..18975)
                     /locus_tag="TVB59_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEL1010085.1"
                     /translation="MSYFERFLSANEAYVALHGTAHLPLKPKTKVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRITDDMLRSLVISQQQLGTREIVVLHHTDCGAQTFTNEAF
                     TAQLHDTLGVDVSDCDFLPFTDVEASVREDMAILQQSPLIPKDVVISGAVYDVATGRM
                     SQVAMPKS"
     gene            19358..19636
                     /locus_tag="TVB59_001188"
     CDS             19358..19636
                     /locus_tag="TVB59_001188"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010086.1"
                     /translation="MKQTKIICLLAAAAVLTLGPISTGQTQPQTVYASQVSGDSCIDL
                     GNGWFKCPKDIGGWDILFNQDYQAPSRSPFFTWISGWFNFIWQWFKSF"
     gene            complement(19797..21158)
                     /gene="radA"
                     /locus_tag="TVB59_001189"
     CDS             complement(19797..21158)
                     /gene="radA"
                     /locus_tag="TVB59_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEL1010087.1"
                     /translation="MAKKKARFICGECGYQSPKYLGRCPNCSAWSSFVEETEVKDVKN
                     ARISLTGEKSKPIKLKHINGVRYQRIQTEMNEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSIQLADKGTVLYVSGEESAEQIKMRSDRLGQTDNDFYLYAETNMQAIRAEIE
                     AIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELLQLAKSNHIATFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFDMQSGGLVEVLNP
                     SQVFLEERLDGATGSAVVVTMEGSRPILAEVQALVTPTVFGNARRTTTGLDFNRVSLI
                     MAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTNPQEAFLGE
                     IGLTGDIRRVTRIEQRINEAAKLGFTKLYAPKSSLQGIDLPKGIEVVGVTTVGEVLKA
                     VFT"
     gene            complement(21225..21671)
                     /locus_tag="TVB59_001190"
     CDS             complement(21225..21671)
                     /locus_tag="TVB59_001190"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEL1010088.1"
                     /translation="MTRIRGFELVSGFTDTDLLPKRETAHAAGYDLSVAEETSIAPGE
                     IVLVPTGVKAYMQDGEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPANEGHIFAQ
                     MKNITDQTITLSAGERIVQGVFMPFLIADGDQAGGERTGGFGSTGG"
     gene            complement(21873..22640)
                     /locus_tag="TVB59_001191"
     CDS             complement(21873..22640)
                     /locus_tag="TVB59_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HEL1010089.1"
                     /translation="MIDLQEILARMNPNQKINYDRVMQQMTKVWARESIRPRILMHVC
                     CAPCSTYTLEYLTQYADITVYFANSNIHPKDEYHRRAYVTQKFVAEFNDKTGNSVQFI
                     EADYVPNEFVKTVRGLEKESEGGDRCRVCFDYRLDKTAQKAVELGFDYFASALTISPH
                     KNSQTINDVGIDVQKVYTTKYLPSDFKKNNGYRRSVEMCEEYDIYRQCYCGCVYAANI
                     QGIDLVQVKKDAKAFMADKDLEADFPRIRFSYAGKEI"
     gene            complement(22802..24598)
                     /locus_tag="TVB59_001192"
     CDS             complement(22802..24598)
                     /locus_tag="TVB59_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1010090.1"
                     /translation="MKILRFFWFYFKRYKLSFVVIFFAIVLATYLQVKAPVFLGDSLA
                     ELGEWVQRYYKAQALSKMTGQPLVEPSMAPFRTVMGKLLLAYLFTAVANLIYSLLFTR
                     VISHSTNRMRKGLFGKLERLTVGFFDSHKDGAILSRFTSDLDNIQNSMNQSLIQVLTN
                     IALYIGLVLMMFRQDSRLALVTIASTPVALILLVVIITMARKYTDLQQKEVSALNAYM
                     DEKISGQKAIIVQGVQQDAIDGFIEHNERVRAATFKGRLFAGLLFPVMNGMSLLNTAI
                     VIFAGSTIVLGDKSMSTAAALGLVVTFVQYSQQYYQPIMQIASSWGELQLAFTGAGRI
                     QEMFDEKEEVRPEHAPVFTALKEGVEIKHVDFGYLPGQKILSDVSISASKGKMVAVVG
                     PTGSGKTTIMNLINRFYDVDAGSITFDGRDIREYDLDSLRQRVGIVLQESVLFSGTIA
                     DNIRFGNQTISQKEVETAARATHIHEFIMSLPDGYQTQVSDDENVFSTGQKQLISIAR
                     TLLTDPQVLILDEATSNVDTVTESKIQKAMEAIVAGRTSFVIAHRLKTILNADEIIVL
                     KDGKVIEQGSHHELLRQKGFYAELYHNQFVFE"
     gene            complement(24598..26307)
                     /locus_tag="TVB59_001193"
     CDS             complement(24598..26307)
                     /locus_tag="TVB59_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1010091.1"
                     /translation="MLRNAVMKYKWYAALSLVMISGVVASALLQPHYLKDVLAAIMEN
                     DQTRIAEVGFWLLVIAGIGLVSGAVNTILSAKIAQGVSADIREQTFRKIQSFSYANVE
                     AFNAGNLVVRMTNDINQIQNFVMMLFQILLRLPILFVGAFILAVQALPSLWWVLVLVV
                     VMTMVVIGLVMSQMGPRFGIFQRLMDRINQIAKENLRGVRVVKSFVQEKSQYDTFKEA
                     SNDLLGLNLFIGYGFSIMQPILMLVSYMAIYLSLYLVSGLVKTDPAVIGNMASFMTYM
                     GQISFAITMVGFMGMQASRALTSIGRIREILETEPAMTFVNHEQEELTGSIVFDDVSF
                     TYPNDSEATLKHISFEVEPGQMVGIVGATGAGKSTLAQLIPRLFDPQEGQILIGGKAL
                     PSISQETLRDTVSIVLQKAILFSGTIADNLRQGNPYADQLALENAARIAQAKEFIDRM
                     DAGYQSEVEERGNNFSGGQKQRMSIARGVINNPKILVLDDSTSALDAKSEKLVQEALN
                     KELKETTTVIIAQKISSVVKADKILVLDNGRLIGEGTHAELVASNPIYREIYETQKGR
                     EEN"
     gene            complement(26300..26749)
                     /locus_tag="TVB59_001194"
     CDS             complement(26300..26749)
                     /locus_tag="TVB59_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEL1010092.1"
                     /translation="MPRIIAELRELTHQVEQISEEIAKKYDLQHLAGPQGHVLVFLHC
                     HQDRDIFVKDIEKELQISKSVTSNLVKRMEKNGFIRVVASATDKRCKQVVLTSAGRAK
                     LPVLKECRRDIERYFFKEISREELLTVKKVIDQLKQNIRAYKGDTDA"
     gene            26959..27978
                     /locus_tag="TVB59_001195"
     CDS             26959..27978
                     /locus_tag="TVB59_001195"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEL1010093.1"
                     /translation="MPKQKVAILGPGSWGTALAQVLNDNGHEVRLWGNIPEQINEINT
                     RHTNSHYFKDIVLDEAIKATLDLKEALADIDAILFVVPTKVTRLVAKQVAQVLDHKAI
                     VMHASKGLEPGTHERLSTILEEEIPAQLRSEVVVVSGPSHAEETIVRDITLITAASKD
                     ITAARYVQTLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGYGDNAKAAVI
                     TRGLAEITRLGVKLGADPLTYSGLSGVGDLIVTGTSVHSRNWRAGAALGRGEKLKDIE
                     NNMGMVIEGISTTKVAYEIAQELGVYMPITSAIYKSIYEGADIKESILGMMSNEFRSE
                     NEWHT"
BASE COUNT         8374 a         6756 c         5153 g         7750 t
ORIGIN      
        1 ctctattttc ctttttcagc ccttgtatac tggggaggat ataatagccc ccctaaaata
       61 aaatgtgcta agcaatatga gaaacaggtc gctgagcttt tcttttattt gccacaaggc
      121 acatacgaca gctgttaaca tttaaataga ggttaaaaga taggacaatc aaagcctgct
      181 gattgctgac aataataaaa gcaccccaag gcattgaccg acttagccaa gtgctggggt
      241 gcagtttttt catatgacct tttagttgtc atcaaggact ggatcgatag cctctagcta
      301 gagagtagcc tttagcctaa cttggccgac ttctgcccta gcagcaactg ctccagcatc
      361 agcaagacgc atatcagcaa tgtcctgtga gtttgtaaag acaaccataa cggtgctgtc
      421 tttttgagca gcttcaagca ctggcaaaga gacctgagcc aataactgcc cagctactac
      481 ctcctgacca gcaacaatat cagagctaaa ggcagcttct cccagctcaa cagtatcaac
      541 accgatatga atcaagacct caagaccagc tggagtaacg atgccataag catgcttggt
      601 cggaaaaacc gtcatgaccc ttcctgttac gggtgcataa atagcgccct cctgaggaat
      661 aatagcaaag ccatcgccca ttagcctttc tgaaaagaca ggatcactga cactggtaat
      721 aggaactaat tgtcccttag ccactgataa aatacgatcg cttaacgcat cagctttttt
      781 tgctgataat aattgcttcc acttctttat catgttaatc ttctctacct aatagttgat
      841 tgatttcttg actatacaag atagccttac caccataaat agcctgaatg ccatttttaa
      901 catctaatac agctgttgct cccagtgagg ttaaaacatt cttgttaacc aagctgctat
      961 ctgacagaga cactctcaag cgagtcgcgc aagcggttac atcttcgatg ttagcttgtc
     1021 ctcccaaagc ctcaataata gctaatgaca cctcacgaag tgatgagctt tgagtattag
     1081 tagtctctgc ttgtccttct gcttctacct gagctaccat tcccggtaca gcaacctgga
     1141 atttgctcac aaagaattta aagacaaagt aataaaccat aaaccacacg ataccaacag
     1201 ggataacaag tagccagttg gtatgatcat ttccttggaa cacaccaaag attaaaaagt
     1261 caatcaaacc acctgagaag gaattaccga tacgaatctt taataaatca gcaactaaga
     1321 aagaacaacc atctaagaaa gcatgaacta catagagcca aggggctaca aataaaaagg
     1381 caaattcaat aggctctgtg atccctgtta gtaaggaagt caaggcacta cttgaataaa
     1441 agctaccaac ctttttacga ttagcctttg gaatagcgtg atacatagca agacaggcag
     1501 caggtagtcc aaacatcatg gttgcaaaac gtcctgcaaa aaagcgtgtc ccgtaagtaa
     1561 acaagtcggt atggttagca tcagccaatt gcgcaaagaa gatattttgt gctccttgga
     1621 tagtctcacc tgctacaacc tcactaccgc caagtgatgt ataccaaaac attgggtaaa
     1681 tggtgtggtg cagccctact gctcctgtca gacgtaaaaa gaaaccgtac aagaatgttc
     1741 cgatgctccc catatccgca attttttcac caaacactac taggagattt tgaataggtg
     1801 gccaaatgac atagaaaaca ctaccaatca caatcgctgc caatgaggaa acaatcggaa
     1861 taaaacgaga gccgccaaag aagcctaaaa aggctggcag ttcgatcttt cggtacttat
     1921 tgtgaaggct aacaacaact aagccaaccg tcaaagcccc taaaacaccc gtatcaatct
     1981 gagcgtcctt tgctgaaaaa agagtcagat agccgctaat ggttgccgta aagaccaaat
     2041 aagccacagc acctgaaaga ccggctgttc ctttatctcc gttggctaag ccaacagcaa
     2101 caccaatcgc aaaaatcaag gcaatattag caaaaacagc gttacctgct gtgctcataa
     2161 tggtaaaaat agcctgtagc catgcttgat ttaatatcgg aaattgtgca atggcattgc
     2221 tatttgacag ggccccacca atccccaaca acaaaccagc aactggtaag attgagatcg
     2281 gcagcataaa ggcttgaccc aattttgaaa atttcttaaa atccatgtga tttctcctcc
     2341 ttcttgagag ccgccacaaa gcgctctgca atttcctttg gtctggtaat agcaccacca
     2401 accacaatac cagctactcc caaagcctga acagccctgg cctcctctgg actatgaatc
     2461 ttgccctcag ctatcactga tacccctgca tcacacaagg cacttatcag ctccatatcc
     2521 ggacctgtcc cctgacgact ataaggcgta taccctgata aggtcgtccc tacaaaatct
     2581 ataccagcct cataggctac tagaccctct tcaagcgtac tgatgtctgc cataaacagc
     2641 tgctctgggt acttcttcct tatcgatcga ataaagtccg ctatcgctaa gccatcatga
     2701 cgctcccttt gcgtacaatc caaggctatc accgctacat ctaaggccgc taaggcgtct
     2761 acctctgcca tggttggcgt gataaagggc gcttgcggag gatactcctt tttgatgatc
     2821 cctatgattg gcagatccgt caccgcttgg atttccttaa tatctcgaac cccattagct
     2881 cttatcccta ctgctcctgc ttcctctgct gcctttgcca tcagaggcat gatacctcct
     2941 gcctctgaat agagaggctc gcccggcaga gcttgacagg aaacgatcag cccgtctttc
     3001 agagctgtca gtagctctgc cttgcttggt ttttcaagca tgctttctac tccttttatt
     3061 aattttagag aacgttcaca tctttattgt agcagatatt aaaacacttt caatagacag
     3121 cccactttta ggaagtactt tcattttcag agaaaaatcc ttgttttctg aaagtatatt
     3181 caatagcctt aagtatggca aagagctagc ctattgagct atttactaat tgatacaaca
     3241 acagcaaaac cttacaagac ataccttctt accataaaag cctttttgcc agccagctaa
     3301 ggccaaatac ggcaatatgt ctcaacaaga actaccttag gtcctattat tgcttgataa
     3361 gcttgacaaa gagacaaaaa agagagaacc agtccagtcc tctctcgcac ccagcttttc
     3421 aagctctaca atacccgtag tgggtaactc caccgcaagg gttatatata gaacttttga
     3481 ttgtacccaa aaataaccac ttttcaccta cctaatacag ctaacaacgg cccctaacat
     3541 agctgccctc agatccgcta tcttaaacat tatttcaaag gactgacata atcatctggc
     3601 agttttccct tccaatctat ccatttttgc tccgcaattg gaattagttt tcttagctct
     3661 tcttaggtaa acagttccca actggttgga tctgcaatta atgctattgg ggatctttgt
     3721 agaaatgctt tatcactagc tattttctcc tcttctgttg gcagccagca gttatttttg
     3781 acataaaaat ctatttctaa taaaaatttt cggtcacttt ccagtaattg gaaaagctca
     3841 ttagggagtt tatacactac tcgttgtaca gcaattcctc cttcttctct gactagataa
     3901 tattctccct gatgcttcca aacctgttgg ccataaccct tgatttcctc atattgacta
     3961 acatcttccc atgttaattg actgcgtgcc atgtgtgtta tctttcgttt ttatagctta
     4021 atcgataaat actgctcaat ctttttccaa taataccctt acctcgtctg attgaaaagc
     4081 atactctatt tttatttaag ctatttcaaa tccatttttc aagtattcat ctaaactatt
     4141 tgcaattttg agcttcaaga taagactgta cctgaggaat tttttgaaac atgtttttta
     4201 taaaaccaac catcgctttt tcatcatcag tcacgatatt ttcaggagat aaccttttaa
     4261 cagaaaaaac taaatcaggg atcataggat taaaatcaat ataaaaggaa aagttcttct
     4321 ttagtagttt gttgttcttt tgatagaaaa tatatgacac aacttgatat aattctacaa
     4381 cattttttga agttgagaat tgagacagta ttctttcagt ttcatgtggg ataatgctat
     4441 ctcctaaatc atacaaggga tacaagcagc gctcaataag cacatttata tctgtgatcg
     4501 attgaaaata tgagtcttta gcatttattt taaacccaga atcccctcta aagcacttct
     4561 ctaagtgtcc ctttgaacga gcatctaagt aaagttgtcg acgtctttca tcaacgtcat
     4621 tgttaaaaaa tgtttgtgtc atattaatta cctaattttc taattataaa ttgtccttca
     4681 acaatctttt tagtgccatc tttcaaaacg attgtaggat tattcaaggt ataaattcct
     4741 gttgattcca tacttaataa tacatcctcc aattttaagt tactagtatc aatagatggc
     4801 atcattaatt cagactgtga caaagccata tttttacctg cccaagtttt agcccctgga
     4861 atatttaaaa gtgaagaacc tggagtttta ccagtaactg ttctcacttc accgatttga
     4921 tcaaaagatt taacaaactg aggactatat tcatactgaa atgcaccaga caaatactta
     4981 ccttcatcta cccctttgat agcctctatc ataccggaag aaactaaatt accactacta
     5041 tcataaagta atgctatatc ttcagccata cttgttgcaa aatttcccga tttacctctt
     5101 ccaatggtac catattgctc aattgcatta tacaaatctt gaccattcac aattgatgat
     5161 gcacctgtct taatataaag ctgttttata ttctttataa agccatctaa atatatatag
     5221 ttcttatttg aatacatctt ataaaaatct gcttttgtag aaacagcacc gttatctact
     5281 gataattgag cataatcatc taatgtttct acaaattcat cagcctgtct tatcgaaacc
     5341 caactatttc ctttaagatc cctattaaaa atttctatgg ctttctccct aaatgtgata
     5401 agatttagat cagcattctg ttttcttaaa gtattaatta acttttctct tgctacatag
     5461 ctcttaaacc ttgagctctc tgttgccagc ctgctgtttt caaggttctt caaaagctgc
     5521 tggcggttgt aggtcggttt cgtcacccta gctgctattg gctcattcaa gctaaaccgt
     5581 ctggcggcgc ttggagacgc ttggcattgg cttcaaggtg acgagctact ccctgataag
     5641 ctgtcgcagg ctaattatta agaacatgct ttaaaatagc agagctaatc tcggctccgc
     5701 tatcttaaac attatttcaa aggactgaca taatcatctg gcagttttcc cttccaatct
     5761 atccattttt gctctgcgat tggaatcagt tttcttagct cttcttgggt aaaaagttcc
     5821 caacttgttg gatctgcaat taaggctatt ggggatcttt gtaaaaatgc tttatcacta
     5881 gctattttct cttcttccgt tggtggccaa caatcatatc gcaatttaaa agcaatctcc
     5941 cctaaattcc gttttccttg ctccaataat tcaaataaat catacggcag ctcatatact
     6001 actcgctgct cagctatacc accttcatta gtcactagat agtaagttcc ctgacgcttc
     6061 cacacctgtt gaccataacc cttgacttcc tcatattgac taacatcttc ccactctaat
     6121 tgactatgtt ccatgtatgt tctcctttac ttgtactgat atctttcata actccctctg
     6181 gcatatcacc cggataagta cgacctccag gtcgccacca gctattagca cccttttcat
     6241 taccacttgg aatagaaatc cctttctccg aaacaacctc tggtgaaaca tctaagcgat
     6301 agagcggatc attgccaaga taaccctcgt cgaagccgag taagctttca taaaagattg
     6361 atgcatagtc agcttactct tgttcctcct ttcttcagtt ttttatcata atttcatctt
     6421 aaaatttaat caattcgagc aatctaatct cactcatcat ctccttttcc tatttaggca
     6481 tacttctaag tccttcaaag tttttaaaat tggactatca tactgtgttg tatcatcaac
     6541 aaattgtcta gctaaacttg aaaaattaat attcccaaca atccgattat tatcaatatc
     6601 attagtcaaa acataaagat ctcttaatat tcctgaatag tttttttgct tgggatactc
     6661 aagttctatt aactctctaa gcctttgtgt atattgaaaa cagttattat tatccataaa
     6721 tttctccttt tttagttagg aacgatcctt atttcttgaa tccactccaa tggccaccga
     6781 ttgggaagta agacctgatc tccacctcca attaaggttg ttcctgaaga tttaaccgtc
     6841 tgtggggcaa ccttgccaat attcaattga ctcccctttg gtattttaat tacagcctca
     6901 tattgtctag tatttttcca ttctggaagt aaagctgtat ctatttttgc ttgtatacga
     6961 ttagttgcag gcaccgttgt gacaaaaccg cctccagcat ctgacgcccc tccaaaagtc
     7021 ctataaagtg ttatttcctc acctgtaata actgttctat agtgactatc tgtaaatgaa
     7081 tctgcaatcc aaccaggaag attttcctta gccccaactg ttactttact atctatttga
     7141 gttggatatt ttgtaacact ttcttttttt atatagcctc cgaaattaga actctctctc
     7201 gccagcctgc tgttctcaag gttcttcaaa agctgctggt gattgtaggt cggtttcgtc
     7261 actctagctg ctattggctc attcaagctg aaccttctgg cggcacttga ggcggcatag
     7321 cctgctagga tattccctac caaggtagct ctttgggcat cttgctcact gccgcctaag
     7381 agcttggtgc catgatagct ggcctgacca ccgataaagc cgccaacctc accgatcgta
     7441 aactctgtca agcccttggc aacactcttg gtctgaccaa tcagaattag tgctgcactg
     7501 gctgttgtga acagcccgcc gatctggtga taaagcctgt cattccccat gaacaaggta
     7561 tcccgaaggg gattggtagc cactgtaagc ccatcgccaa cgctacctag ataaatgttg
     7621 tgcccagcct catacaggtt cgacgcccca taagcaactg taccactgcc aacaacaaag
     7681 gccccaacca ccaagggagt cgctgcccct gctgtcatga cgatagccgc aaccccaacc
     7741 gctattgtca caaggctgag tgctagatct atccagccct gcttggccct gtcctctgca
     7801 gctactgcct caaaacgggc atgatcccgc tcctgcgctg cttggagacg cttggcattg
     7861 gtctcaagat gacgagccac cccctgataa gctgtcgcaa agcgttttat ggtgttgagc
     7921 tgtcctatat ccccaacctg atagctccca gcccgcttgg gcttactgct gtactctgct
     7981 atcaaggcct tggtcgaagc caaaagctcc ttgaaggcgg ccaagtcctg actggcatga
     8041 ttgctttcgt attgaatgat ggcctcgtcc aagcgatgga tatcagtgat cagctcacta
     8101 taatccacta ctgtcttggc atgactgaca ccagagtagt gaaccaggtc tgataactta
     8161 gctctggtat tctgtagtag ctcaagctga tccttgaggt gggcctgcga gagccgaagc
     8221 tctgactgca gggtcttaaa gacctgaccg ggtaactggg catgactatt actgtctatc
     8281 tggtaatagc cgtccttata cagcaagagg ctagctgagt aatcattcat caggctttgc
     8341 agggtttgta aaagtgtccc atgcacctca ctcagatagc tcttgattga gctagcggtc
     8401 tgaccctgaa ggcgactgtc tccaatcaag gctgacaggg cggtctggat actcgttatc
     8461 ccatctcccc aagcactgat cgtggtttgg gtgctttgtt gaagggaggt aatctcatca
     8521 tatttgatat tatagctcat ttcttcccct aacgttttca atgcgatatc aaaatgtttc
     8581 accaataata gcaatacatt tctttaatat acctctttta ttatatcaaa aaaaacttaa
     8641 tgattatcac accaagctaa gagcattgat gggtaataac atatagctta tccaaccttg
     8701 ttagcaggag tattacaaat aatgtattgc caagaggaaa agctgatata aataggtggg
     8761 acaaacgtgg tcaagaaaac ctttaacacc aagaaaacca tgataattct tgataacatc
     8821 aaatagtgcc tcagctaaat gattatgatg acctttacca aatcattctt tattatctgc
     8881 aagaaaagaa cagtgacatc tcttcgatcc gattacgaat ataaatcaag cttcaaaacc
     8941 gctcttagta cctttattcg ttgccaaaaa tatctcattg aactctctta ttcaaacgct
     9001 aagctagaag caaccaataa actgagcaaa aacataaagc ggcaagcttt ggctttagga
     9061 acttcaaagc taagattccc aatactttta acatcacaaa agagagcacc aagctggtcc
     9121 tctctagata ttagttatta gtcaccccac tacagttgac attgagcctc tttgatgaca
     9181 ctagtcgtga attagtgaga caacaacata gcgattaggg tcgttgccct ctgaatagct
     9241 ctcaacccca tcaatagcag aaactgtttt atgaacaatc tttcgctcgc tgttactcat
     9301 aggatccatg gtataatctt gaccagactc aagcacacgc ttggatacct ttttggtaaa
     9361 gtcaatcagg gtttctgtcc gatgctctac ataatcatga acattcaagg agacagaaaa
     9421 attcttagaa tagcggtcat gtaagaaatt ttgggccagc aattgcagtg atttcaaaac
     9481 cttaccatga tagccaataa cacgacctgc ctctggtgtc tctatctgaa gattgatctg
     9541 acgacgattg ttggtcctct caatagaggc ttcaatatcc atctcataga taatcttggt
     9601 cacatagtca gaaatctcct gtgcagctag ctcaatatcc ttactcatgt ccgctgcagc
     9661 tggatccagc tgactcgcac cagcagctga cgacacaggc tgtgcctttg actgagtagg
     9721 agctgactga gctgtgctta atggacctgt tggctgatga gcatcagact cagcagccct
     9781 tctgtcttgt gatcgaacag ccttcatctc ctcaagctcc acctcatcgg ggttaataac
     9841 cggtgcattt tgacggttga tctcctctgg aacactacgt acggcttttt tatcagcctt
     9901 atagactgtt ttttcattaa tgccttcaat atcaacctga gctggctttt taccaaagcc
     9961 caaaaagccc tttttctcct ttgaaatcac cttgatgtgt gcttttagac gtgacaaccc
    10021 caactcttga agtccttttt caattgcttc ttcaacagtc ttacctgtaa acaataccat
    10081 atcctaaact cctattttct tttcattgct ctcttacgag cgcgacgttc cttagctcga
    10141 cgctcttttt cttcatctgc taaacgttgc ctttcggcaa taaccttaaa gggattatta
    10201 aacagcaaga gctgaacaac ctgaaaggca ttggaaactg cccaataaag caccacacca
    10261 ctggccagat taaagcccat aaagaagatg aacacaggca tcacgtaggt catgatcgtt
    10321 atcatggccg tcttttctct agccgctaga ttggttagcc atgttgataa aaaggtaaag
    10381 acagccgcta aaataggcag aataaagaga tgatcatgtc gcgccagctc aacccataaa
    10441 aaggtgcctt ctcttaagaa agccacacga gtcagagact gaaacaaggc aaacatcacc
    10501 ggcatctgaa tcagcaaggg caaaaggctc atgtaaggat tgacaccata ctttttgtac
    10561 agagcttgac tttcttcagc tagcttcata cgagttgctg tgtctttagc agcatatttt
    10621 ttttgcaggg cctttagctc tggttgaatg tcctgcattt tctgccctga cttgatttgc
    10681 atgttaaaca atggcagtaa aagcaagcga atcattatcg taaataggat aatcccaatc
    10741 ccagtcgatc catcaaagga caaccattgg atcgccttgg caaaaaaata aaccaattgc
    10801 tcccagctac tagatgattg tgctgtcacc tctccacgcc cacaggctac tagtagcaag
    10861 acaagcggca ctagggctgc tgttttaact ctttttttca atctcaaaac cttcctcaag
    10921 caattttgct agctttaaaa catgatgtaa attttgtttg actgcttgat aatctaattc
    10981 ctctgcacct ctcctagcaa taacaacgaa atcctcagac ttgaggtgat cacccagctc
    11041 cattaaaaca tgtcgtatct tgcgctttac cgcatttcga gtaacagcat ttcctagctt
    11101 tttgccaaca gaaatccctg ctcgaaaatg cttgtgctcc cctttcaaat ggtaaatgac
    11161 aaattttcga tttgccatgc tctgaccaag cttaaaaatc gcctggaaat ctttctctcg
    11221 cttgacacga tagcttttct tcaaaactta actcccatat ctaaattatt accattatac
    11281 cataaaacat taaaaagcct caacccttat caatgggcct ataataagag attggaccca
    11341 ctatctaaag gatcagaaca aaaaatgctt ttagtgaatc acggtagctg tcaagtcttg
    11401 atagccttat caatcatact agcaaagaaa caaaaaaata aagcccggta aaccgagctt
    11461 tatctccgct gacttgagca tcagcaaata tgatatccaa acaaagacaa ctgaaacaat
    11521 cattttaata acaagcagcc atatcaaaaa tactatttgt ttatggagag agagagaaaa
    11581 caatattttg attgaattgg ggatggacca ctccattacc taatgatttc gtaaatcttt
    11641 attcatacta gacattatag cgaaaaatca ctaaaaaaga tgacaatttc ctgaaatgtt
    11701 catttttcgt cctaaaatgt cattcaactt aatttttagc gaaaagactt ccacttttca
    11761 aaaagctgtt tcattctcaa acgagagacc atacaagaat caccattttc aaaatacacc
    11821 aattgcttag ccttatcaat tcgaacaaca ttgtcaagat tgaccaagta agaacggtgg
    11881 cataaaaaca gcttaggagc taccgcatga atctcagata agttcccata aaattctaag
    11941 cgctctgttt gcgtccacag gcacaccttg tgaggcgttg ttgcagttgc aaaataaaga
    12001 atgtccttat aaggcagctt taggcgggtc tgcggggtct caaacaaaaa catctcttct
    12061 acttgacgac tcgacatcat ctcataggtg tagcgaatac attcctcaat gcgctcttta
    12121 aattgctgac tatcaaccgc tttatcaata aaatccaagg cagacacctt gtacctaaag
    12181 gaaatagggg cgaactctga atgcgtcgtg acaaaaacaa gcacagcatt gggatccttc
    12241 tggcgaatat ctgaggctag ctctagccca cttcttgatt tgtcaccaat ttcaatatct
    12301 aaaaaataca gctgatgatc tcctctctcc tgaatgctat caaacagctt ttgaggattt
    12361 gaaaacacct ctaattgatt atgaggaatc ctaccctctt ctaatatgga cgccacaatg
    12421 gcctcaatac gactttgttg aatcagattg tcttccagaa taaaaatgtt tagcatggct
    12481 tatctcattt ctaacaattg tctcaaacgg tagtgatcac ttttggttga aaaggtgatg
    12541 tggggatagc gctctaacac agccgagaac tgtagcaggc gcttatgagc atggcttcct
    12601 agctccaatc ggctagcatc aaattgcttg gcaatatcaa cccgcttgag ccttgtacta
    12661 ttttcaatga taaaaaatcg cttgccatct tgattaaaat aggcaatgga taaaaaagga
    12721 cgagagctgc ctttagctga caaaatagca ttatcaataa ctaccttgaa aagaacgatg
    12781 acatctaaca gcctgacaga agagctagca agcgtttcag gaatatcgat gtaaacagca
    12841 atgccctgca gctttgcttc taatagcttg gcatgcaata ggctgcgaat caccgaatcc
    12901 tgaacattat caagggctga taattcaggt gttagctgcc tgatagagct tgctgattct
    12961 tggataactg tttgatagac cttagaaata gcagctatat ctccactatc aatactatcc
    13021 tttagactaa ttagaatatt ttctgaatca tgcttaatag ccctgatctc acgacaaagc
    13081 cgctcaatat actgattgtg cttttcaagg taagcaacac gctccttttg tgccagagcc
    13141 aatctttgag atagctgatc cttagcaaag cggtccagct tgacaatgac ccagatgagc
    13201 agcatgaggt aaagaaaaat catgacagag cggtaacgaa aataaatctt gaaaaaatct
    13261 ccttggatat tgatcatgca gtgaaccatc acatagtaga aaagtaaggc tgcattcatc
    13321 caaaagaccc acttctttag cttgtcctca ctgataaact taatcaaggt caaatcaacg
    13381 ctaaaaatat agctaaacag gtaaaaggcc ggcaaaacca atgcatgaca gaccatcaat
    13441 agacctatgt cattattgat ttgatgaatg ctgtagccta aaaccgctgg caaaaggaaa
    13501 gagccaataa tacgaaagag cagctcaaca atcataatcg caaacaagcc attaaacaga
    13561 tgctcagaag cctttttatg aggtgcaaag ccaacactga cagcaacaaa caccagctga
    13621 tcaactagca gcacatgatc cagcagcaga ttagcaacaa caaagcaggc accaaccaaa
    13681 agcaatgatc taacagctag cttaatgcct gaaaatgtcg aaaagatgac ccagctattc
    13741 acaaagatca gagcataaaa gaatgacata cctagcataa aataaaactc tactctttct
    13801 ctatttttgg catgattagg gtctgactaa actgataatc atgactcctg gtgcgcaagg
    13861 atagctcagg atatttctgc aaaatccgct tggcattaga caagcctatc cctcgaccgc
    13921 tcccctttga ggaatagccc tcttcaaaaa tcctactaat catgaccctt tcgtccttgg
    13981 tcgtattggt tacggtgaaa atctgctgat catcagataa aaagtaggct atcgccactg
    14041 ctggctgggc tgtctctaga gcagcctcaa tagcattgtc acaaaaaata gatacaagca
    14101 gcaataaatc aagctctgag atatagctat cccgaatccg atctggaact tctaggctta
    14161 aggcgattcc tgccttctca gccttaatga tttttgatga tagcaagctt tttatcgagg
    14221 atacactgat tttactgagc tttgaaatat tgtaatgctt atcgtcccaa taatccgtcg
    14281 cctcatctac cgtttgggca tagacagtct gtacatctga cacagagcca gagtcaatag
    14341 cctgccccag cctttctagc ctcttgaggt aaactagctg aaatacctta acacccttat
    14401 aaagcttttc tagatgcttt ccataggttt ccagattagc aatataagcc tgctgttcct
    14461 tttttaattc ctgttttaag aattcctttg attgatgatt aaaataagac agtaaataaa
    14521 tcaacaatag ggtaaagatg agaaacagca ccttataaga cgttgacatc attatcgggg
    14581 atttaaggtc aagaaaggga tcagtaaatc ctaaaatcat aaagagatca atatagtagg
    14641 ccaaactaaa gagcaaaaac aagctataaa agctactggc cttatcaaac ctgtcagctt
    14701 taacaatctg cttgtaatcc tttcccacaa aataattaat caaagcaaag cttgggaaaa
    14761 tcatcacata agcaataaag tctaggacaa ggtgtctgac atagctgcca ttaactgaaa
    14821 aaatataggg aagtacaatc gctaaaataa agcgtgataa caaatcaaca aacactccgg
    14881 gaacaaaggc caagaataga gcctttaagc taaagcaggg ccgcttttct aaggctaata
    14941 cagctagcag caataaagga tcaattatca agggcggcaa taaagcaaac tgattcaaaa
    15001 agagagctgc tgtcaggaca aaaatctgct tccaaagtgc cagtttaatg tctgataaaa
    15061 aggaaaaaat actaatttct gtcacataat aaatcatcag tgatagtaat aaaaagagat
    15121 aataaatatc agtcattctg cctccttacc aactttatta ttttaacaca ctttgtgtca
    15181 atccctatta tatgaatttt ttatataatt cagcaagcgc aaaaacagtc catagctggt
    15241 ttgtgacagc gtttgcaaat cagatgtcaa tcattaaagc aaattaaaat atctgaccag
    15301 ccttacctta tctagggaaa aatattgtat aacaaataat ctaagaaaac cagtgacaat
    15361 ttaatattta ttttaataat atcttccacg ctcatcaaaa attaagcaga taagcctgct
    15421 ggattatgac atctagctat gcgctactgg gcgtcgtgtc gctagctcaa gcacactaaa
    15481 aaagaatgaa gcaaacatca gatatctcat ctctgcttca ttcatgatgt tatttatgat
    15541 catcgtccag cctagaccaa actactagct gcgatagtgt ttaaagcata ttggcaatat
    15601 gctcaatcga ttgttcacgt ccaaggaggt aaatggtatt tggcagctct gggccatgca
    15661 tttctccaga aacagcaata cgaattggca taaagaggtt cttgccctta atgccggttt
    15721 ctttttggac agccttgatt tgtgggaaaa tgttttctgg cttaaagtcc tcatctgaca
    15781 tcgcctctag cttttccttg aaggccttca gaactgttgg aacagtctca gctgccatca
    15841 cttctttttc ttttgcggtc agctctggga aatctgagaa aaataaatca gtcaatggaa
    15901 caatctcatc agcagagctt aattgaggct gatagagctc aactagcttc tctgcttttt
    15961 cagtcaagcg gcctgctgct tcaagaaatg gcttacaaag cgcatataca gcgccaagat
    16021 cagcatgctt aaagtactca ttgctcatcc agtccatttt tttctgatca aaggctgctg
    16081 gcgacttgct aagacgaatc tcatcaaata aggcaatcaa ttgctcacga gaaaagatct
    16141 cagcctcccc gccaggattc cagcctaaaa gggcaataaa attaaagact gcctctggca
    16201 tatagccttt tttgcggtaa tcctcaataa actgcagggt attggtatca cgctttgata
    16261 gctttttacc tgtctcagaa ttaatgataa gggtcatatg accaaagacg ggtgcttccc
    16321 agccaagcgc ctcgtaaacc atcaactgct ttggcgtatt ggcaatatgg tcatctccgc
    16381 ggataacgtg tgagatttgc atatcgtgat catcaataac aacagcaaaa ttgtaggttg
    16441 gatagccgtc ttttttctgg attacccagt caccaccgac attgccaccc tcaaatacga
    16501 tatcgccttt taccatgtct gtccatttgt aaacaccagc ctcattgacc gctaaacgaa
    16561 ccgtaggcac aatacctgct gcttcacgct ctgcaatata ggccgccttt tcatatgctg
    16621 acatgccaag gtattcattg acatagcgag gtgtttcacc agctgcctct tgacgctcac
    16681 gctctgctgc cagctcctcc tcagtcacat aagacttgta agccttgcct tctgccaata
    16741 attggtcaat gtattgttga taaagggcta gacgctctga ctgacgataa cgctcgtgcg
    16801 tctcaggact ttcgtcccaa tctataccaa gccattttaa attttccagc tgagaacgct
    16861 cgccgtcctc gacatgacgc ttacgatcag tatcttcaat acgaataata aagtcaccgc
    16921 catgatgacg agcataaaga tagttaaaga gcgctgtccg cgcatttccg atatgtaaaa
    16981 ggcctgttgg gcttggtgca tagcgcacac gaattggttt agacattctt tttctcctat
    17041 ggtttcattg aaagaaggga tcctgggcta taaaccgttc ctacggtagg cttgctctat
    17101 gagaaaatgg tcgataagga acaaaaatac agctaatccc ttggaaatct aaagatttca
    17161 atcgctccta ttatagcaca acttcaagca ttgggcgaca aaaatcaact tagaacagct
    17221 gcataacgaa aatgcatgta accattttct agctacatgc attgttttca tctacttctg
    17281 atattttgat atcatcagct gttcacattc agcttaattg tagcctgaat tgatttgaaa
    17341 aagaccatac cactgatgag aaaatcgcta tcaaaaacgt aaagatcctt atgcgtttgg
    17401 cgtggcctag agctaggata gctctataag cagctcattg gcaagcagtg ctgcctcttt
    17461 caatagcttc atagcatgcc tagctataga tattagtcag gctattgacc tgcattgatg
    17521 tcaagctaca ccccagcaaa gaaagcgaca atatactctg gcaaccacga acctgtcata
    17581 tccatttcaa tccatcaatt ggcaaggctt ggtttacttc caactgctta atggccgcct
    17641 gtgacaatat agctctgtaa aactccagca aattgctgaa ggttcaggct ttgcacatag
    17701 acatctccgt atccgctaaa ggtattgacc actccctcac ctgtaccaat agactgcata
    17761 aagccatttt ccaaatgaat atcataatcc aaatcctgac tccaagccac cacatggcta
    17821 ttatcaatcg tcatgctgtc gccatgaagc gtgatttttt taatcgaacc aaaagcattg
    17881 accaataggg ttccttctcc ttgtgttgac atcacaaaga agccaccctg accgctaaat
    17941 aaggccttac caagtttttg gcgcttcatg gtgtagtgag ctgagccatc taaagccaag
    18001 aaggctccgt cattcaaacg gtattgatct acccctagct caagagcaat aacctgacca
    18061 ggcattgaag gggcaagcgc tagcttgcca ctaacatcat tagcaatcgc ctgtgtgata
    18121 aacatggatt ctcctgaaac cattgaacgg ccaatggcac caaccagctt gccaagacct
    18181 gagccacgcc cattgagctt ggtgtttaag ctgattgacg gtgtgtggta aaccatactg
    18241 cctttttgta gaaagacaga ctcccccatg tccaaatcaa tttcaacaag aggaaactgc
    18301 atgctgctgt caatagtata ggtcattcga ttataggcca taacaccact cctttgtatg
    18361 attttgttga tacaatcaag tatagtcttt tttggcagca ttgtccacta gctactgtcg
    18421 ccgccattcc taaccagtct caaagccata ctacaaaccg atcagctgtc aggatttcgg
    18481 catcgccacc tgagacatac gtccagtggc aacatcatag accgcaccac taatgaccac
    18541 gtcttttgga atcaacggtg attgctgcaa tatagccata tcctcacgaa cacttgcttc
    18601 cacatcagta aaggggagaa aatcacagtc agacacatct actcccagag tatcatgaag
    18661 ctgcgctgta aaggcttcat tggtaaaggt ttgcgcccca caatccgtat gatgaagaac
    18721 aacgatctca cgcgttccca gctgctgctg cgaaatcaca agagaccgaa gcatgtcatc
    18781 tgttatccgt ccaccagcat tgcgtaaaat atgggcatca ccaagcgcta aacccaaggc
    18841 ctgcgccaca tgcagtcttg agtccataca ggtcacaata gctaccttag ttttgggctt
    18901 taggggcaaa tgagcagtcc catgtaaggc gacataggct tcattggcag ataaaaagcg
    18961 ttcaaaatat gacatgaata cggtcctccc agactaatct ctaagctatc tcagccttga
    19021 gctgtctgtc tatcttatca tcttttgcct gaaatgtctg aatgctgaac tgctttttaa
    19081 cacaagcaga tagcactagc ctaactgaaa ccagaggtag gtgagccagc cttgacattg
    19141 gaagcaagct tagcagcccg ccctttgagc cgctaaagta agggcagcaa gaacgtgaca
    19201 aaatcagtta attgtcattt taattaaaaa acgaaactac ggagacaaac tgataaattg
    19261 ctatttctcg ctatcagcca gtatgctaaa ctcttctcag aaggccttgg cagtcgctag
    19321 ctgctaagcc aataatacta aattaaggag aatagcaatg aaacaaacaa aaataatctg
    19381 cttattggct gctgctgctg tcctaaccct aggtcctatc agcacaggcc agacacaacc
    19441 acagaccgta tatgccagtc aggttagtgg agacagctgt atcgatctag gtaatggatg
    19501 gtttaaatgt cctaaggata ttggaggatg ggacattctt tttaatcaag attaccaagc
    19561 gccttcacga tcgccatttt tcacttggat ttcaggctgg tttaacttta tatggcagtg
    19621 gtttaaaagc ttctaagatc tactaatacg ctatccatat cataaggctc ttagaggcta
    19681 gctctctaag ggctttttgg ttctacggaa cactataagg accttccaat actactggtc
    19741 ttaaaataaa aaagactagg aatagctccc ctagtcctca tgttaaaaac aacaacctaa
    19801 gtaaagacag cctttaagac ctctcctact gtcgtcacac caacaacctc aatccctttt
    19861 ggcagatcaa tcccctgcaa tgagcttttc ggagcgtaaa gcttggtaaa gccaagctta
    19921 gcggcttcat taatccgctg ctcaatacgg gtcacacgcc gaatatcacc agtcaagcca
    19981 atctctccta aaaaggcctc ctgagggttg gttggttttt ccttgtagct agaggcaatg
    20041 gccacagcaa ctgccaagtc aatagcaggc tcatctagct tcacaccgcc tgctgacttg
    20101 aggtaggcat cttgattttg tagcagcagc ccacatcgct tttccaagac agccataatc
    20161 agactgacgc gattaaagtc caacccagtt gtcgttcgtc tagcattacc aaaaacagtc
    20221 ggtgtcacca aggcctgcac ctcagctaaa atcggtctgc tcccctccat ggtgacaacc
    20281 acagcagagc ctgttgcgcc gtctaatcgt tcctctaaga acacctgact gggattgagg
    20341 acctccacta gcccacctga ttgcatgtca aaaataccaa tctcattggt tgagccaaaa
    20401 cgatttttaa ccgctcgcaa gatacgaaag gtatgatgcc tctcaccctc aaaataaagg
    20461 accgtatcaa ccatatgctc cagcatgcga ggccctgcta gggtgccctc cttggtgaca
    20521 tgtcctacaa taaaggttgc aatatgatta gacttagcta gctggagcag ctcagcagtg
    20581 acctctcgaa cctgactgac cgagccctga acacccgaaa tctccggact catgatcgtc
    20641 tgaatagaat caataatcaa aaaatccggc tgaatggctt caatctctgc tcgaatagcc
    20701 tgcatattgg tctccgcata gaggtaaaaa tcattgtcgg tctgtcccaa acgatcactg
    20761 cgcatcttga tctgctctgc cgattcctct ccagagacat ataaaacagt tcccttatcc
    20821 gcaagctgga tagaaacctg caagagcagc gttgacttac caataccagg atcaccacca
    20881 atcaaaacca agctccccgg cacaacacca ccgcccagca cacgattgaa ctcattcatc
    20941 tctgtctgga tacgctggta gcgaacgcca ttgatatgct ttagcttgat gggcttactt
    21001 ttttctccag tcaggctaat acgggcattt ttgacgtcct tgacctctgt ctcctctaca
    21061 aaggaagacc aggcagagca attagggcag cgccccagat atttgggtga ctgatagcca
    21121 cattctccac agataaacct cgcctttttc ttagctataa cacatttcct ccttgaatct
    21181 aagcatcaac tggctacaag cacgtgaagc agcctgctaa taccttatcc tcctgtcgaa
    21241 ccaaaaccac ctgtccgctc accaccagcc tgatcaccat cagcaatcaa aaaaggcata
    21301 aatacgccct gaacaatgcg ctcaccagct gacaaggtaa tggtttgatc cgtaatattt
    21361 ttcatctgag caaaaatatg cccttcattc gcagggttac catagtagtc accatcaata
    21421 acacccacag aattgatcag aaccagtccc tttttacgag gattgctgga gcgatcatag
    21481 agataaagca cctcaccgtc ttgcatatac gccttgaccc ctgttggcac aagtacaatc
    21541 tcacctggtg caatgctggt ctcctctgca acagataagt catagcctgc tgcatgagct
    21601 gtctcacgtt ttggtaataa atcagtatca gtaaagcctg acacaagctc aaagcctcga
    21661 atccttgtca tgattaacct caagagccct tgtcagtgcc tgcagcagct gtaaaatcac
    21721 ctgccaggac agcagacaaa agcactctta tcccttttct ttttttagtc ctcttattat
    21781 aaaatattcg taaaggaata gcaaaaaagt aggggctgca ccccaaaaat caccgactgc
    21841 ccccctctat aacgcaacaa aatgcaagag ggctaaatct ccttgccggc atagctaaac
    21901 cgaatccttg gaaaatcagc ctccaaatcc ttatctgcca taaaagcctt ggcgtccttt
    21961 ttcacctgaa ccagatcaat cccttgtatg tttgcagcat agacgcagcc gcaatagcac
    22021 tggcggtaaa tatcatattc ctcacacatt tcgaccgacc tgcgatagcc attatttttc
    22081 ttgaaatcac taggcaaata cttagtggtg taaacctttt gcacatcaat gcctacatcg
    22141 ttaatcgtct gtgagttttt atgagggctg atggtcaagg cactagcaaa ataatcaaag
    22201 cccagctcca cagccttttg tgccgtcttg tccaagcgat aatcaaagca aacacgacaa
    22261 cgatccccgc cctcagactc tttctccaag cctcggacag tcttgacaaa ttcatttggc
    22321 acataatctg cctcgataaa ctgcacgcta ttacctgttt tatcgttgaa ctctgctaca
    22381 aatttctgag taacataggc cctgcggtgg tattcgtcct ttgggtgaat atttgaatta
    22441 gcaaaataaa ccgtaatatc agcgtactgg gttaaatatt ccagcgtgta ggttgagcag
    22501 ggagcacagc aaacatgcat caaaatgcga ggacgtatag actccctcgc ccagaccttg
    22561 gtcatctgct gcatgacccg atcatagttt attttctggt ttggattcat tctagctaga
    22621 atctcttgta agtcaatcat tacatcttct accttctatt gtctgtctct tttattatag
    22681 cacattgcct tgacatgctt tgcatcaaaa aactccgcca aagcggagtc gatcggcaaa
    22741 agctgttttg atggttttta agaataacaa cagcagctta tgtaatgatc atttttagaa
    22801 gctactcaaa cacaaactga ttgtgataaa gctcggcata aaagcccttt tgccttagca
    22861 gctcatggtg acttccctgc tcaataacct taccgtcctt tagaacgatg atttcatcag
    22921 catttaaaat ggtttttagg cggtgggcaa tcacgaagct tgtgcgacct gccacgatag
    22981 cctccatagc cttttgaatc ttactttcag taacagtatc aacatttgat gttgcctcgt
    23041 ccaaaatcaa gacctgagga tcggttaaca gcgtacgagc aattgaaata agctgctttt
    23101 gaccagttga aaagacattc tcatcatctg acacctgagt ttggtagcca tcaggcaagg
    23161 acatgataaa ctcatgaata tgcgttgcac gcgctgctgt ctcaacctct ttttggctga
    23221 ttgtctgatt accaaagcgg atattatcag caatagtccc agaaaacaag actgactcct
    23281 gtaggacaat accaacccgc tgacgcagac tatccaagtc atattcccta atatcacgac
    23341 catcaaaggt aatagagcca gcatcaacat cataaaaacg attaatcaga ttcatgatcg
    23401 tggtcttgcc agaccctgtc ggtccaacaa cagcaaccat tttccccttt gaagctgaaa
    23461 tcgacacatc tgacagaatt ttttgtcccg gcagataacc aaagtcaaca tgcttaatct
    23521 caaccccttc ttttaatgct gtaaagacag gagcatgctc agggcgaacc tcttcttttt
    23581 catcgaacat ttcttggata cgaccagcac ctgtaaaggc cagctgcaat tcaccccagc
    23641 tagaggcaat ctgcataatc ggttgataat actgctgtga atactgaaca aaggtcacca
    23701 ccaagccaag agcagcagct gttgacatgg acttgtcacc aaggacaatg gttgagccag
    23761 caaagatgac aatagctgta ttcaaaagac tcatcccatt catcacagga aacagcagac
    23821 cagcaaaaag gcgtccctta aaggttgctg cacgcaccct ctcattgtgc tcaataaagc
    23881 catcaatagc atcctgttgc accccttgaa caataatagc cttctggcca gaaatcttct
    23941 cgtccatgta agcatttaaa gcactgacct ccttttgctg caaatcagta tatttgcggg
    24001 ccattgtaat gatgacaacg agaagaataa gcgccacagg ggttgaggct atcgttacca
    24061 aggccaagcg actatcctgc ctaaacatca tcagcactag accaatatac aaagcaatat
    24121 ttgtcaagac ctgaatcaga gattggttca tggagttttg aatattatca agatcactgg
    24181 taaagcgtga tagaatagca ccgtccttgt gactatcaaa aaagccaact gtcaagcgct
    24241 ccaatttgcc aaataagccc ttacgcatgc gattggtcga atgcgaaata acccttgtaa
    24301 agaggagact ataaataaga ttagccactg ctgtaaagag ataagccaac aatagctttc
    24361 ccataaccgt cctaaaaggc gccatagagg gctcaactaa gggctgaccc gtcattttgc
    24421 taagcgcctg agccttgtaa tagcgctgca cccattctcc cagctcagct agagagtctc
    24481 ccaaaaagac aggggcctta acctgcaggt aggttgccag gacaatagca aagaatatca
    24541 caacaaaaga gagcttataa cgtttaaaat aaaaccagaa aaatcgcagg atcttcatta
    24601 gttctcctct cttccctttt gagtttcgta aatttcacga taaatcggat tggaagcaac
    24661 cagctcagca tgcgtccctt ctccaatcaa tcgaccatta tcaagaacaa gaatcttatc
    24721 tgccttgaca actgacgata ttttttgtgc gatgatgact gttgttgtct ctttgagctc
    24781 cttattcaag gcctcctgaa caagcttttc agatttggca tctagagctg atgtcgaatc
    24841 atcaagcacc aaaatcttag gattgttaat cacaccacga gcaattgaca ttctctgctt
    24901 ttgaccgcca gaaaaattat tgccacgctc ttctacctca ctctggtagc cagcgtccat
    24961 acggtcgata aattccttgg cctgcgcaat gcgtgctgca ttttctaaag ccaattggtc
    25021 agcataggga ttgccctgac gcagattatc cgcaatagtc ccagaaaaaa gaatagcctt
    25081 ttgcagcaca atagagacgg tgtcgcgcag agtctcttga ctgatgcttg gcagagcctt
    25141 accaccaatc aggatttgcc cttcctgtgg gtcaaacaaa cgcggaatca gctgcgcaag
    25201 ggtcgacttg ccagcacctg tcgcaccgac aataccaacc atttgaccgg gctcaacctc
    25261 aaacgaaata tgctttagag tggcttcact gtcatttgga taggtaaagc tcacatcatc
    25321 aaagacaata ctgcctgtca gctcctcctg ctcatggtta acaaaggtca tagcaggctc
    25381 tgtttctaaa atctccctga tccgaccaat cgaggtcaag gcacgacttg cctgcattcc
    25441 cataaaacca accatcgtga tcgcaaagct gatttgtccc atataggtca taaaggaagc
    25501 catatttcca ataacagcag gatctgtttt gaccagccct gaaaccagat acaaggacaa
    25561 ataaatggcc atgtaagaca ccaacatcaa aataggctgc atgattgaaa agccatagcc
    25621 gataaacaaa ttcaagccca gtaggtcatt tgaagcctcc ttaaatgtgt catactggct
    25681 tttttcctga acaaaggact tgaccacacg cacaccgcgt aggttttcct tagcaatctg
    25741 attgatccta tccatcaagc gctggaagat cccaaagcga ggacccatct ggctcatcac
    25801 cagcccaatg actaccattg tcatcacaac cacaagcacc aagacccacc aaaggctcgg
    25861 taaggcctgc accgctaaaa taaaggcacc gacaaataaa atcggcaagc gcaacaatat
    25921 ctgaaaaagc atcatcacaa agttttggat ttgattaata tcatttgtca ttctaacgac
    25981 aagatttcca gcattgaagg cttccacatt ggcataagaa aaggattgga tctttctaaa
    26041 ggtctgctca cgaatatcag cagatacccc ttgagcaatc ttggcagaca agatggtatt
    26101 gaccgcacct gacaccaagc caatccctgc tatcactaac agccaaaaac ccacctctgc
    26161 aatccttgtc tgatcatttt ccataatagc agctagaaca tctttgaggt aatgtggctg
    26221 gagcagggca ctggctacga ccccagaaat catcactagg gacagagccg cataccattt
    26281 atacttcatc acagcatttc taagcatctg tatctccttt ataagctcgt atattttgtt
    26341 tcagctgatc gataaccttt tttaccgtca gcagctcttc tcttgaaatt tccttgaaaa
    26401 aatagcgctc aatatctctg cggcactcct ttaataccgg cagcttagcc ctaccagccg
    26461 aggtcaagac aacctgcttg cagcgcttat ctgtagccga ggcaacaact cgaataaagc
    26521 catttttttc catacgcttc accagattac tcgtaaccga ttttgagatt tgaagctcct
    26581 tttcaatgtc cttgacaaaa atgtctctgt cttgatggca atgcaaaaag acaagaacat
    26641 gcccttgtgg accagcaaga tgctggaggt catacttttt agcaatctct tcgctaattt
    26701 gctcaacctg atgggtcaat tcacgaagct cagcaatgat tcttggcatt tccttcctcc
    26761 ttagttctca tgataaccat tttagttctc ttgggaacta ttgtcaacca aaaaggctta
    26821 cgatctgact atcttccctg ctacttaccc tttgctagca ccactgagct gacaggctag
    26881 gccagcagac cttttctatt agagttaggc cttgtcttat gatataataa ggtgattagc
    26941 tcttaaagga gaataaaaat gccaaaacaa aaggtagcca ttttgggacc tggctcttgg
    27001 ggcacagccc tggcacaggt cctaaatgac aacggacatg aggtccgact atggggaaat
    27061 atccctgaac aaatcaacga aatcaacaca cgccatacta atagtcatta ttttaaggac
    27121 attgtcctag atgaagccat caaggcaacc cttgatttga aggaagcatt ggctgatatt
    27181 gatgctatat tgtttgttgt gcctaccaag gtgactcggc ttgttgccaa gcaggtcgct
    27241 caggtcctag accacaaggc tattgtcatg cacgcctcaa agggattaga gcctggaacc
    27301 catgagcgcc tctcaacgat cctcgaagag gagatccctg cccagctgcg cagtgaggtc
    27361 gtggttgtgt ctgggcctag ccatgccgag gagaccatcg ttcgtgacat taccctaatc
    27421 actgcagcct caaaggacat cacagctgct aggtatgttc agaccctctt tagcaaccac
    27481 tacttccgtc tctacaccaa tactgatgtg atcggtgttg aaaccgctgg cgctctcaag
    27541 aacatcattg ctgttggagc cggtgctctg catggccttg gctatggtga caatgccaag
    27601 gctgctgtca tcacacgcgg tcttgcggaa atcacacgac taggggtcaa gcttggggca
    27661 gaccctctga cctatagcgg cctatctggt gttggtgatt tgattgtcac aggaacatct
    27721 gtgcattcac gcaactggcg agctggtgct gctcttggtc gcggcgaaaa gctcaaggac
    27781 atcgaaaaca atatgggcat ggtgattgaa ggcatttcca caaccaaggt agcctacgaa
    27841 attgcccaag agctaggggt ttatatgcca attaccagcg cgatttacaa atctatctat
    27901 gaaggtgctg acattaaaga aagcattctg ggcatgatgt caaatgaatt tcgctcagaa
    27961 aatgaatggc acacataagg aaccacaaat caaggaggaa ctcatgacaa aggtcagaaa
    28021 agccattatc cca
//
LOCUS       DARYNN010000029        26438 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.029, whole genome shotgun sequence.
ACCESSION   DARYNN010000029 DARYNN010000000
VERSION     DARYNN010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26438
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.029"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(153..356)
                     /locus_tag="TVB59_001196"
     CDS             complement(153..356)
                     /locus_tag="TVB59_001196"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010094.1"
                     /translation="MKRYIIEQLANETDTITIMFTNGKQHTFCQVANECPDNPNIIEL
                     KLSDAQYIVLVNLDQVTYISHHS"
     gene            416..877
                     /locus_tag="TVB59_001197"
     CDS             416..877
                     /locus_tag="TVB59_001197"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010095.1"
                     /translation="MQANRIFYGKEKPTNAVAGDCWFRDNELMILKDNWEASVNNLKS
                     PKVIGEIEIDLEQHDVLLTARGNRPPLLMIDGIMLGGVSKVIIINELSESCAIVSLNE
                     YIKENLFPFDDFESLQRLFQKGHQKLSVRELCLEKRLGEHSYQDHRKSCDE"
     gene            1019..1735
                     /locus_tag="TVB59_001198"
     CDS             1019..1735
                     /locus_tag="TVB59_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HEL1010096.1"
                     /translation="MNQLINITLNENQEPVVSGRDLHKVLEIKTAYKDWFPRMAEYGF
                     EEGQDFSSFLSKSTGGRPSQDHVLKLDMAKEIAMLQRNEKSKEVRKYFIQVEKDFNSP
                     EKIMARALLMADKKVHKLEAQIEADRPKVLFADAVSASKSSCLIGELAKILKQNGINI
                     GQNKLFQWLRTNGYLISRRGESWNQPTQKSMQLGLFELKKTAINHSDGHTTTNVTPKV
                     TGKGQQYFINKFLNQEYLPV"
     gene            1769..1918
                     /locus_tag="TVB59_001199"
     CDS             1769..1918
                     /locus_tag="TVB59_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010097.1"
                     /translation="MPEDLIKQLEAGSEFLAKTCLHSKIIITVDGVRLVETKEFHPVS
                     GTLLD"
     gene            complement(1915..2115)
                     /locus_tag="TVB59_001200"
     CDS             complement(1915..2115)
                     /locus_tag="TVB59_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KTSC domain-containing protein"
                     /protein_id="HEL1010098.1"
                     /translation="MQRQYVSSSNVRSVGWENNTLEVEFNNGSIYHYHNVSQTEYRSV
                     LVGSVGSNIHRLAKIHTYTRIV"
     gene            2226..2510
                     /locus_tag="TVB59_001201"
     CDS             2226..2510
                     /locus_tag="TVB59_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1010099.1"
                     /translation="MDSRLLQMLDEFEAGLIDRKIKVIGMLNNETEIYPLELNKKQIS
                     KMLGVDPKTFDVRFNSHKDFPRIETGGREKYPRDLVIEWYSKNWERTGIR"
     gene            2507..2653
                     /locus_tag="TVB59_001202"
     CDS             2507..2653
                     /locus_tag="TVB59_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010100.1"
                     /translation="MIKKLFNFIFAKPKEESRQPYQQPRGFLDFETGKRIEIDPITRK
                     EYFV"
     gene            2857..3102
                     /locus_tag="TVB59_001203"
     CDS             2857..3102
                     /locus_tag="TVB59_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEL1010101.1"
                     /translation="MLLTILSNSDEWRVYPEELAKRCRDSVDAVRTQLKALEKAGYIR
                     SYRKSLGGRYGTETHRFCSDTKISDEVFQELLKELNC"
     gene            3264..3647
                     /locus_tag="TVB59_001204"
     CDS             3264..3647
                     /locus_tag="TVB59_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HEL1010102.1"
                     /translation="MDEKKLFENFQLTFGRMISPFEIEDIQKWIHQDNMPIDVVNLAL
                     REAVENNKINWKYINKILVEWHKAGDTTIEKVKERLQRFEDSKEQRHATISNVPSWSN
                     PDYQGPTYDDLKVNPSEVSDGAGDF"
     gene            3628..3861
                     /locus_tag="TVB59_001205"
     CDS             3628..3861
                     /locus_tag="TVB59_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010103.1"
                     /translation="MAQEIFDGFNALINKMYGRQSSIETFNRFVEYCQKRREENGVEP
                     VLNPINLFAFGVGITTEEANKLRIKRYKQENGL"
     gene            3858..3998
                     /locus_tag="TVB59_001206"
     CDS             3858..3998
                     /locus_tag="TVB59_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010104.1"
                     /translation="MTKQYRETLIWHRASHKEREKLLDFGLVDKSQYMTLLRQLRKKY
                     AI"
     gene            4007..4213
                     /locus_tag="TVB59_001207"
     CDS             4007..4213
                     /locus_tag="TVB59_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010105.1"
                     /translation="MTPEQVEKAKIRAKRELETFSIYLDQAIVEYGSTLSPQEVFLAA
                     GFAYLGAGQTDIHAAIEGLYEQIQ"
     gene            4348..5076
                     /locus_tag="TVB59_001208"
                     /pseudo
     CDS             4348..5076
                     /locus_tag="TVB59_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017827951.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
     gene            5253..6464
                     /locus_tag="TVB59_001209"
     CDS             5253..6464
                     /locus_tag="TVB59_001209"
                     /inference="COORDINATES: protein motif:HMM:NF018751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1351 domain-containing protein"
                     /protein_id="HEL1010106.1"
                     /translation="MSENLTLFENLNDIKPAEPAELSFDFEFTPAEIKIKGKEKLEEI
                     LAAYAKKYDGYTVTAETFEDDAKVRAKLNTLQKDINNSVKTKLAEYNNPLDDVKQWVN
                     SIIEPIKKITKTIDEGVKHFEEIERQKRANTIKETFEAAIAETGADIDIRLFESNFDD
                     MSAKGYFMADNVRVNTATKKAINKLVAEEVAKKQEHEQALIQISEAAAKADFGPAIYI
                     KRFENGAQLADILQAIADDKLLADKVREEEKRKAELSKRVEEMTALAQREGLQPGKYV
                     KLLEDGKSALVVFETLMDDSKKMQAKIAQKNAEAHQQQIEQTEYMSEASNSGVNELET
                     DKVINNIIKQENALEAKIEPNKSVTKWQGDFKITFPDSETAKLFGGQGGLYEKHGVIV
                     EKLGEWVKIND"
     gene            6457..7293
                     /locus_tag="TVB59_001210"
     CDS             6457..7293
                     /locus_tag="TVB59_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease-like domain-containing
                     protein"
                     /protein_id="HEL1010107.1"
                     /translation="MTKLTEENYYQDREWLSNSRFKAFLDCEAKALAVENNEWEDTRD
                     ETPLLVGNYLHSYFESPEAHEKFKAENGAKMISSRGVTKGELKKEYKVAQNMIETLET
                     DEIFNLMYHGQSGDNVLKEMIIYGEILGIKVKGKVDSINLTKGYFCDLKTMKSIHSDE
                     WSNDLRKRVPGVAANIIGFKYHIQMGLYQELLRQMTGKTLQPLIIAISKENVPDKELI
                     ELGQTWLDEGLQLFENNVEHVHEVIIGKAEAKSCGRCDYCRSQKKLNRVVDLDDLIAG
                     IF"
     gene            7478..7819
                     /locus_tag="TVB59_001211"
     CDS             7478..7819
                     /locus_tag="TVB59_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010108.1"
                     /translation="MEQIKITGTDTILILDRVDRAFVIEGNLAERWRFTSKFIKIDDE
                     LSLDEDGELFEIVYDLMLEAKPHNVINLTSSYFAKEHKKDTDEIIKVFAFIEDNKKNI
                     FETLGIRGVLE"
     gene            7816..8328
                     /locus_tag="TVB59_001212"
     CDS             7816..8328
                     /locus_tag="TVB59_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010109.1"
                     /translation="MSNLVLSLDISTSGTGWALFKGSDLIQSGVLKHKSDSYFERGRY
                     MASKLRLIQSRALKKYDCSFSTIAVEKNSVMGPNQQSMLKIGIVTGIILGRLIADNVV
                     FINVSTWRKHWKFSYKDRSKKAMKAQSKAKAAENFGKIVKDDEADAVLIGAYYVNQGY
                     LDGLETHDYY"
     gene            8550..8777
                     /locus_tag="TVB59_001213"
     CDS             8550..8777
                     /locus_tag="TVB59_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010110.1"
                     /translation="MTKNDFLTGFVLILLAACIFAAGFVIGSDCSSEHYEQQMTGLRM
                     QLVNTQQQLKRASEDRARRTKRIADLTGNGG"
     gene            8781..9203
                     /locus_tag="TVB59_001214"
     CDS             8781..9203
                     /locus_tag="TVB59_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEL1010111.1"
                     /translation="MIDEIELDLQKPEIPQFVADYIDDMHKNARTLRYAFKYMESNIK
                     MHKWCVFERQETFVNAFLYGYTIKKEKLYIVEIPNPNSGIEHKHIALARLANGKLGFS
                     EIIDTDFYSREDVRLTESEIRKDFDWAWREGFAKEVTE"
     gene            9371..9601
                     /locus_tag="TVB59_001215"
     CDS             9371..9601
                     /locus_tag="TVB59_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003077369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010112.1"
                     /translation="MAYLREERETVIHYDELDDCWTFETNVRRHITKIEKRIELYEIL
                     SEEFDDRGRRIYICAKMKTGTVSPFAKPPRRK"
     gene            9978..10412
                     /locus_tag="TVB59_001216"
     CDS             9978..10412
                     /locus_tag="TVB59_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HEL1010113.1"
                     /translation="MTFFPEIDIQKTKSNAKRKLKEYPRWRRIANDVDTQKVTATYSF
                     EPRQPHGVHSKPVERLALNRVSAEQELDAIEQAVSMILEPERRRILYDKYLSPYKKAD
                     KVIYTELCMSESFYYDTLDIALLAFAELYREGSLIVEQGVFS"
     gene            10950..11024
                     /locus_tag="TVB59_001217"
     tRNA            10950..11024
                     /locus_tag="TVB59_001217"
                     /product="tRNA-OTHER"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
     gene            11183..11674
                     /locus_tag="TVB59_001218"
     CDS             11183..11674
                     /locus_tag="TVB59_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011834794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEL1010114.1"
                     /translation="MAKLTIKQQKFIDEYIICGNATEAALKAGYSKKTAGQIGEQNLK
                     KLEIKSAINERLKQLESSKIASAIEILQVLTAVLRQDLTEEVVTLNPVTGEYVTMQKK
                     PSIAEVIKAAGELLKRYPIQEQIEKIKQENELLRLKIETVKGAKPDTHLMEKLLEVIE
                     DGG"
     gene            11709..12962
                     /locus_tag="TVB59_001219"
     CDS             11709..12962
                     /locus_tag="TVB59_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEL1010115.1"
                     /translation="MRRPFNYELEVNEGTPRSGKTTAGHFRYARYLIESEDENHLVTA
                     YNQEQAYRLFIDGDGTGLMHIFDGNCEIKHDERGDHLLVTTPKGNKRVYYKGGGKVNS
                     VGAITGMSLGSVVFCEINLLHMDFIQECFRRTWAAKLRYHLADLNPPAPQHPVIKDVF
                     DVQNTRWTHWTMDDNPILTAERKQNIINSLKKNPYLYKRDVLGQRVMPQGVIYGLFDM
                     EKNVLDTLIGEPVEMYFCADGGQSDATSMSCNIVTRVRDNGKISFRLNRTAHYYHSGA
                     DTGQVKAMSTYARELKAFIDWCVKKYQLRYSDVFIDPACKALREELHAIGILTTGAPN
                     NAHDVNSKAKGIEVGIERGQTLISDGDFYLVNHKEEKYDHYHFLKELGLYSRDDKGKP
                     IDANNHSMDEFRYSVNVFVGRYKMK"
     gene            12972..14471
                     /locus_tag="TVB59_001220"
     CDS             12972..14471
                     /locus_tag="TVB59_001220"
                     /inference="COORDINATES: protein motif:HMM:TIGR01542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEL1010116.1"
                     /translation="MFRNLWTKIKGVMQKMGLIKGLKDLNLHREIELSDKHYDSIQIW
                     KELYQGYHDKIHDYYEKSILDGRKKKKRLTLNMPKVVTSELATLIFNEKCEINIGSEN
                     ESLTKLITETLEKNNFTQEFQRFLEYSFALGGMAIKAYLKKDGTIGLNFVQADSFIPI
                     SWDNAGISEAVFVDTQHRGKYKYTHLEWHTWESELYVVAHELFRTDKSNDDVGIRVPI
                     TEIYPDLKSQVVIEKLSRPLFVYLKPNSANNIDLSSPLGISIYHNSFDTLRAIDIAYD
                     SFEREFRLGRKRILVPATAIRTVVDSEGNFHRYFDATDETYEAFHTGEDSKIQDIKDI
                     SVELRVDEHIAAINALLNLLSMQIGFSPGSFSFDGVSGVKTATEVISENSKTFRTKQS
                     HETMVEATLKNLVAIIVDFGDLYGLIEGESKYNVTVTFDDSIAQDRTQDAQYYIGLVA
                     AGLISKKKAMMKLFNLSEEDAELEIQTIHEESRTTNDMSIDLFGLDGDA"
     gene            14471..16081
                     /locus_tag="TVB59_001221"
     CDS             14471..16081
                     /locus_tag="TVB59_001221"
                     /inference="COORDINATES: protein motif:HMM:NF017919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010117.1"
                     /translation="MDYDTHIQLSFDLIELYSDVERELLTSIGRRFAKHYDEMVAGDI
                     MDWQIRQLLEVGELRKEHIEIMRKSARVSRERMIEMLTEAGYTSAGRYEDFFKEAYVK
                     GLIKLNPSAADNSMRLLRVLNTYINQAEDTLNLVNTTMLQSGQDTFLDTVNQVVAYVS
                     TGIKTPQVAMRDALKNAGQKGLTVFRAKNGAQWSTETYLNMITRTMNSNISNAMEDER
                     RHEYGVDYIEVSSHAGARPRCAPYQGRIYYDGVGDDPLEKYPHFSETSYGEAAGLFGV
                     NCGHHKYPYVPGMSKQTFFPYSKSENDKTYAESQVQRKLEREVKQLKRERAILTAAKD
                     KEGAKLASQRLENKWQELRQFTAQTGRTRRYDREKSLNTILSEDKKKAIVKDNLKIRD
                     EYRAIKKAIPEVAPKNLETYYDMRYNGGKIYEDLVRDYKDYIRWSKAEFPTKKSFEGH
                     IDSHLKEFPGLTGKQYQKKAADLLSRPITDNILGYDTDSRRVRYDLENNIFALGRVKQ
                     GTITTMLKPKEGVDYFDNDWKREFDNLK"
     gene            16047..16268
                     /locus_tag="TVB59_001222"
     CDS             16047..16268
                     /locus_tag="TVB59_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010118.1"
                     /translation="MTGKESLIILNDLEYVHCPVCGTLTEVYDICDTCKWQNTGETNI
                     DGGPNYITLEEARRRWANGEPLRNFFKDQ"
     gene            16320..16604
                     /locus_tag="TVB59_001223"
     CDS             16320..16604
                     /locus_tag="TVB59_001223"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010119.1"
                     /translation="MNKRIEKKRRTQMMLDRILRIVELMSQATDDNFAILEKRLEKAE
                     KRNEELMEIILVNVKEVNNRFDELEICQKIVEDDVAELKKAKKKGWFSRK"
     gene            16690..16929
                     /locus_tag="TVB59_001224"
     CDS             16690..16929
                     /locus_tag="TVB59_001224"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010120.1"
                     /translation="MAVIIVQTRGGDIEVPTPLPAMQANKAIQSQLFDKELTFLCVDN
                     HAFAKTEVLHVLVETEEDEELPQSKHKEEETCYMD"
     gene            16914..17516
                     /locus_tag="TVB59_001225"
     CDS             16914..17516
                     /locus_tag="TVB59_001225"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010121.1"
                     /translation="MLHGLKHRLFKLAPDTGAGGGAEVTSETNAEAGRVEQTVSQQQA
                     DPVDTEAIKNQAINEVLSQLGVSSVEDAKANLASWNEYQEGQKTEFQKIQDSLTVANN
                     SLAERDTMIASLQAQLAAAQMGVPAENTSDVITLANSLVHDKTDINAAITTVLEKYPH
                     FKGGDADVADKPNFVTQTQSQTETTEDAFFKALGLTIKED"
     gene            17518..18390
                     /locus_tag="TVB59_001226"
     CDS             17518..18390
                     /locus_tag="TVB59_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003039217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010122.1"
                     /translation="MSINYITKHEGIFEKKLMQGALTSNLETPKVNWLGAKSFELPTI
                     SVTGYKAHTRSKGYNAGTVSNDKNTYTLGFDRDVEFFVDKADVDETNQELSMANISNT
                     FITEHATPEVDAYRFSKIATNAIDNSHFKQEDDYSTTNVYERLKAAILPIRKYGAGNI
                     IIYVSSEIMDFLERSKDFTRSIATTSPQGIDTRVTSLDGVQLIEVWDDARFKTKFDFT
                     TGFVKDGSGKDINFLIVAKPAVIAKAKFNSIYLFAPGQHTEGDGYLYQNRLYHDLFVL
                     KSKQDGVYVSHKSA"
     gene            18401..18649
                     /locus_tag="TVB59_001227"
     CDS             18401..18649
                     /locus_tag="TVB59_001227"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010123.1"
                     /translation="MKTYEKDNQVYKVQEGSELEIQLIADGFKEIIEANEKETDITKM
                     KLDKLKAYAENEGIIIPEDIKKKEDVLAFIKEQQQRGE"
     gene            18652..19038
                     /locus_tag="TVB59_001228"
     CDS             18652..19038
                     /locus_tag="TVB59_001228"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010124.1"
                     /translation="MLTFDFYNKGYCGSQLNEEKFGELSKRAERKILALIGLKKEQVK
                     NLPLDILEAVKMAVCAQIEYLNAIGVESAIGVTSVTQAKVGNFSYTDGKKATVSASVG
                     SVGVSPDVLDYLLPSGLLYKGVNTRW"
     gene            19032..19376
                     /locus_tag="TVB59_001229"
     CDS             19032..19376
                     /locus_tag="TVB59_001229"
                     /inference="COORDINATES: protein motif:HMM:NF022130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010125.1"
                     /translation="MVKEVKPIPKELLVDTVTYLAVGNKDSWGAETVVSTELSQVLVQ
                     PRSSIQRGQQNESNSYELLLFFDCVNSLPVDHQFKVDDKISYLGKEYRIASVEVLKAF
                     DQSPHHYEVMLE"
     gene            19373..19726
                     /locus_tag="TVB59_001230"
     CDS             19373..19726
                     /locus_tag="TVB59_001230"
                     /inference="COORDINATES: protein motif:HMM:NF022564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010126.1"
                     /translation="MIGFKVEVIFNASKLIAKSEASAKTARFALSGQIKKDSDKYIPA
                     REWNLRDSGRVTERSVSWHTPYARRLYYNPQYNFSKDKNPNAQGKWFEVAKANHAEHW
                     YELTKKAYGAEFRGD"
     gene            19729..20097
                     /locus_tag="TVB59_001231"
     CDS             19729..20097
                     /locus_tag="TVB59_001231"
                     /inference="COORDINATES: protein motif:HMM:NF024103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010127.1"
                     /translation="MTFIDFLLRKVQEVSGAEPVLGIMGNSDKVAIIPMAGNFDNRAL
                     DESKIRIFTFQVLAKSKKQQEAFLTTENLVNGLDGLSNEPFTGGYLIKLECTTTTNFV
                     EKDSDKNYLYTALFRAELGG"
     gene            20101..20598
                     /locus_tag="TVB59_001232"
     CDS             20101..20598
                     /locus_tag="TVB59_001232"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010128.1"
                     /translation="MAADKPTFYLQSEHKLEISEDGKTWMRLAGGISELEPDGNEEVS
                     QDAYLDGSESDVTGGQLVLALTGHRLVGDKAQDWIYARQFRYGGKRRGFTRWTLPGGK
                     TQFTFASTFANIKGPSGAANGKGEIEFEIHSNETLVPNKVVVEVTKTNKELASEALGL
                     ERQER"
     gene            20618..21025
                     /locus_tag="TVB59_001233"
     CDS             20618..21025
                     /locus_tag="TVB59_001233"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010129.1"
                     /translation="MVRQFEFKKTVEEIEIAGEIYLLPLDDDNLLRIQRDFISYGKEI
                     EELQKVEVEKGDPDDLADNHKQQLLVMKKVIESPFGEGSFEKLYEASGHSLMNMVDLL
                     DYLVELVAEKVEQNKARATKAKEKYYSSKRKKK"
     gene            21033..21650
                     /locus_tag="TVB59_001234"
     CDS             21033..21650
                     /locus_tag="TVB59_001234"
                     /inference="COORDINATES: protein motif:HMM:NF018553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010130.1"
                     /translation="MKLTETYEVLADAFEFGGHIVTVDLAFDVVLRVMELLADAEVND
                     YAKIVWTLDMLLPYFDRTELSFDEEFEIFEYILKTFIYEQEDGEDDSLGGMSQTKTMH
                     FEKDAELIFASFFQSYHLDLFEQQGKLHWRKFMSLLMNLHKDTPFKEVVSYRVMKVPN
                     KDEASEEYIKHVKKMKRIYSLEDESEHQALNDDKLSALAARFGGE"
     gene            21651..24098
                     /locus_tag="TVB59_001235"
     CDS             21651..24098
                     /locus_tag="TVB59_001235"
                     /inference="COORDINATES: protein motif:HMM:TIGR01760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HEL1010131.1"
                     /translation="MADGSVIIDTLLKTEKFNQGVGKLQGKLAGLGSKLTSIGTGLTL
                     GLTAPIVGIGAASLSTFTTFESQMNRVKAISGATASEFRKLEDQAIKLGASSVFSATE
                     VAQAQEMMASAGFKVVDILKAMPGVMSLAAVSGGDMALASEAAATAVNMFGLEAKDAA
                     HVADVFAQAAADTNAEVGDMAEALKYAGPVAGALGISLEETAAAIGIMSNAGIKGSQA
                     GTTLRTSLSRLTDPTKKMRGIMSELGLEFFDVNGKMKSLSGITKELQTKMGDLTDSQK
                     SAAISTLFGKEAMSGMLALVNSAPGALDKQTQALINSNGAAKEMADTMNSGVKGSIEE
                     LKGSLETAGISIGKILAPALTSVIGAITSLVNWFNNLSPTMQNVVVVLGSLLAAIGPV
                     VLIIGVVTTQIAAFQQGVGLVFNAVKGLQAAFAFLTSPIGLVIVAIGALIAVFVYLWN
                     TNEQFRTKIIEIWTAISNFLQPIIQFIGNFIRETWTQLATFWNENQATIMTIAQTTWS
                     FIQTIFTTAIEMIKLAVSVFLGLLQSTWSVTFNSLKVIAQVAWAFISNVFKGSLGSIL
                     AVASAIFEQIKSTIDLAMKIIQNIIKIILSAIEGDWDGVLEGIKGIVSAFGDFIQSTF
                     SNMMDTAKRLVGAGIDTVKGIFDSLWNIDLFGAGQAIINGFLNGLRSMWGAVTDFVGG
                     IASWIAANKGPISYDRVLLKPHGKAIMDGLGNSMKTNFKDIQKDVSGMADDLTRSFQI
                     KRFNGFLPEKYTTKLDELKKYAQATLGGMILAPNMAVQPTVVVNISNEADSDIIRQKV
                     NAKNAQDAIINQLFKKG"
     gene            24102..24863
                     /locus_tag="TVB59_001236"
     CDS             24102..24863
                     /locus_tag="TVB59_001236"
                     /inference="COORDINATES: protein motif:HMM:NF017520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HEL1010132.1"
                     /translation="MFSIEFLDGERLSADERGWKVKEMSSSGLEQNVVSESPKMRSGR
                     LVYGLYHGIKTYQLVFTKIIKDTLDYSRLVDEVNYYFLRDEPYYLYRDFRKKADRVDL
                     PKKRAKVFTKSIDHQKNGLKVEFTAKLESYELPYEEDTEVQRVTWTATHSWHNKGGHR
                     LDPRYCPMKMTITVSGSGAELKVLFNGQPYFWYKKSVKQGDIFIIDGTDVEKNRYNCF
                     EDCHKQTSFLKTGNNRIDIQGASCEALFEYRLLYL"
     gene            24874..>26438
                     /locus_tag="TVB59_001237"
     CDS             24874..>26438
                     /locus_tag="TVB59_001237"
                     /inference="COORDINATES: protein motif:HMM:NF018329.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1010133.1"
                     /translation="MQVKTKQGVFYVNADYTVVEKQGDYPKLTCTIPIKGNETWIADC
                     QELDRLYPAGEQDEFIIINPIKVTKGSSYDLEITAIGAFHFEFVKARLYEELPERMYT
                     LDYLLDLLFKDSRFSYKLQGDYSTRRFSGFGDDNKLTLFHHLMERFQTEFKVVGKVVL
                     VNTKVGKDTGFQFRYLRNIKDTKYSVDVTNLMTYVKGYGAWFDENDHSKGRLIVDYES
                     PLSKEYGKLDGKPVVDERMSLKESLIKKCKLAVDRSVSVSLTTTLVSLKQQDYQGAAR
                     IGDSIWFIDERISIEKKIRFSVVTTYYNAYDDILKQDVTLGDKDTYSRYQSLENSSQT
                     ETNDFQKAMSSKLAEVQDDVKKTHILVSGTTRIFFSTEFPQDNPKGTIKEDDILYRNH
                     DGTTLMYRWNGVQWELVPLVNDPDRWREELEKQISEAVEKLKQEQKVINQRTDKELEE
                     FRDTLKNLSLPEEAIKKITEAIKVDDIPSIKQSFDDLKNKVSETSETARLNAEIIGTD
                     GKTRYNKNLLVGDP"
BASE COUNT         8910 a         4551 c         5923 g         7054 t
ORIGIN      
        1 tgacaaaatt ttcagaagaa ataaaaatag taaggacgaa gtcttctgtt tatgtaaaca
       61 gcgtcttaga cgttgcagat aaaaaagacc ccgcgtctgt tgtagcagtc gcagagcttt
      121 taaaggcgta taagtcgtta acagaattgt aatcaactat ggtgacttat atacgtgact
      181 tgatcgagat tgaccaaaac gatgtattga gcgtctgata gtttcagttc aataatattt
      241 ggattatcag ggcactcatt tgcaacttgg cagaatgtgt gttgcttacc atttgtgaac
      301 atgattgtaa tggtatcagt ttcattcgct agttgttcga taatatatcg tttcatacaa
      361 tcacctcctt tctgctcata ttatagcagt taaggacaac tagagaaagg acactatgca
      421 agcaaatcga attttttacg gaaaagaaaa accaacaaac gcagtagcgg gcgattgctg
      481 gtttagagat aacgaattaa tgatactcaa ggacaattgg gaagctagcg taaacaactt
      541 aaagagccct aaagttatcg gagagataga aatagaccta gagcagcatg atgtactgct
      601 gacagccaga gggaaccgtc ctccactatt aatgattgat gggataatgt tgggcggagt
      661 atctaaggta ataattataa atgagttatc cgagtcttgc gcaattgtct ctcttaatga
      721 gtatatcaag gagaatttgt tcccttttga cgattttgaa tcacttcaaa ggttatttca
      781 aaagggccat cagaaattat ccgtacggga actttgctta gaaaaacgtt taggtgagca
      841 ttcttatcaa gaccatcgaa aaagctgcga tgaatagtaa aagttttctt accgctcgca
      901 agagctttct cgtaatcctg agtcagtagt ttaacagaga gatctaattg atagtcgtac
      961 acttttgttt atcctccttc cactaggata actacattat acaacagaaa ggaacaacat
     1021 gaatcaacta ataaacatca ccctaaacga aaatcaagaa ccagttgtca gtggtcgtga
     1081 tttacataaa gtacttgaaa tcaaaacagc ttataaagat tggtttccaa gaatggctga
     1141 atatggtttt gaagaaggtc aggactttag ctcatttttg agcaaaagta caggaggtcg
     1201 tcctagtcaa gaccacgttc taaaactaga catggcaaaa gagattgcta tgttacagcg
     1261 taacgagaaa tctaaagaag tccgtaaata cttcatccag gtcgagaaag acttcaacag
     1321 cccagagaaa atcatggcaa gggcgttgct gatggcggac aagaaagtgc ataaattaga
     1381 agctcagatt gaggctgacc gacccaaagt actatttgct gatgccgtaa gtgctagcaa
     1441 atcatcttgt ctgattggtg agttagctaa aatcctgaaa cagaatggaa tcaatattgg
     1501 tcagaataag ctatttcagt ggcttagaac gaacggttat ctaattagca gacgcggcga
     1561 gtcatggaat cagccaacgc aaaaaagtat gcagcttgga ttgtttgaac tcaaaaaaac
     1621 agccatcaat cactctgacg gtcacactac aacaaatgta accccaaaag ttactggtaa
     1681 aggccagcag tattttatta ataaattcct taatcaggaa tatctgccag tttagaaagg
     1741 aaacaaaacc aacgaaaagg agaaaagtat gccagaggat ttaatcaaac aactagaagc
     1801 tggttcagaa tttctagcaa agacatgttt acatagcaag attattatca cggtggatgg
     1861 tgttcggctt gtggaaacaa aagagttcca cccagtgagc ggaactctac tagattagac
     1921 aatacgtgta taagtgtgta tcttagctaa tctatgaata tttgagccaa cagacccaac
     1981 aagaacagaa cggtattccg tttggcttac attgtgataa tggtaaatag aaccattatt
     2041 aaactcaact tccaaagtgt tattttccca accaacactt cggacgttac tagatgaaac
     2101 gtattgacgt tgcataactt tttctccttt ccgcgatgat agctttatta tagcacgcaa
     2161 ggagaataca aaaaaagtcc gacgggaatc ggactcgaca ataatattta tgaggtaatt
     2221 ttatcatgga tagtagatta ttacaaatgc ttgatgagtt tgaggcgggt ctgatagacc
     2281 gtaaaatcaa agtcataggc atgcttaata acgaaacgga aatttatccg ctagagctta
     2341 acaaaaagca aatcagtaag atgctgggag ttgatcctaa aacatttgac gtaagattta
     2401 atagccacaa agattttccg cgcatcgaaa cgggaggtcg ggaaaaatac ccacgagatt
     2461 tagttattga gtggtatagc aaaaactggg aaaggacggg gataagatga ttaaaaaact
     2521 atttaacttt atttttgcaa agccaaaaga agaatcaagg caaccttatc aacaaccgag
     2581 aggttttctg gattttgaaa caggtaaacg aattgaaata gatccgataa caagaaagga
     2641 atacttcgta tgatgcatca aattaatata tcgcttagaa attttgtcga gactggagag
     2701 attgacaaca tcttcgacat ttttagaatt ttagatttct actttcggga ggtggtcagc
     2761 tgatgcagta catttttcaa gacgttgaga gggagttaca cgagcgttag taatgagttt
     2821 gtcaacgata aaaaacttta taacaaggaa aagggattgt tgttgaccat tcttagcaat
     2881 agcgatgagt ggcgagtata tccggaggaa ttggctaaac gttgcagaga tagtgttgac
     2941 gctgtcagaa ctcagctaaa agcacttgag aaagctggat acatcagaag ttatcggaag
     3001 tcgcttggcg ggcgatatgg taccgaaacc catagatttt gctcagacac aaaaataagt
     3061 gatgaggttt ttcaagagct gcttaaagaa ttaaattgct aatgtgcaaa ttgctaatgt
     3121 gcaaattgct aatgtgcaaa ttgctaatgt gcaaattgct aatgtgcaaa ttgcctaact
     3181 aataaatact aacactaaat aaatactaaa taataataaa tactaacaaa caataagcat
     3241 catcatcaac agcaggagga gctatggacg aaaaaaagct ttttgaaaat tttcaactaa
     3301 ctttcggaag aatgatatcg ccatttgaaa tagaagatat tcaaaagtgg attcaccagg
     3361 ataatatgcc gattgatgtt gttaaccttg ctttaagaga agcggtagaa aacaacaaga
     3421 tcaattggaa gtatatcaac aaaattttgg tggagtggca taaagctgga gatacgacga
     3481 ttgagaaggt caaagagagg ttgcagagat ttgaggatag caaagaacaa cgacatgcaa
     3541 ctatctcaaa tgttcctagc tggtcaaatc cagactacca aggcccgaca tacgatgatt
     3601 taaaagtaaa tccaagcgag gtgtcagatg gcgcaggaga tttttgatgg atttaatgcc
     3661 ttaatcaata aaatgtatgg cagacaatct agcatagaga cctttaaccg atttgtcgag
     3721 tattgtcaaa aaaggagaga ggaaaacggg gttgagcctg tattaaatcc gatcaatctt
     3781 tttgcattcg gcgttggaat cacaacggaa gaagctaata aattaagaat aaaacgctac
     3841 aaacaggaga atggattatg acaaaacaat atcgagagac acttatctgg catcgggcaa
     3901 gtcacaaaga gcgtgagaag ctgcttgatt tcgggctagt tgataaatca cagtacatga
     3961 cactattacg ccaattgcgc aagaaatatg cgatttagga ggaaatatga caccagaaca
     4021 agtggaaaaa gcaaaaatca gagctaaacg agaacttgaa acgtttagca tctaccttga
     4081 ccaggcgatt gtcgaatacg gaagtacgct aagtccacaa gaagtctttt tagcggcagg
     4141 gtttgcctac cttggtgcag gtcagactga catacatgcg gccatcgagg ggttatatga
     4201 gcaaatccaa tgattttaat tttagcgatg actgggaaag caactatttc gaggtccaag
     4261 ctttgctagg gcaagagata gacaagctcc aaaacagggt catagcgcta agccaggaaa
     4321 acaatagatt aaaagcgagg aaatgaaatg gcaagtgaaa ttgtaacaat tcaaaaagat
     4381 atcactgata tcgttaattc aaaaattagt atgcttcaga acgaaggtct tgtaatagcg
     4441 ccaaactatg ctccagcaaa tgctttgaag tcagcattct ttaaaatttt aaaaaccaaa
     4501 gacagaaata agaggcctgc tcttgaagcc tgcacaaagg actcaattgc gaactcgctc
     4561 cttgaaatgg tcacccaagg attatcacct gcaaaaaatc aatgctattt tatcgtttac
     4621 gggaatgagc tccaactgca aagatcatat ttcggaacaa tggcagtttt attgcagcag
     4681 aaaaaaatta aatcaattaa gtcagaagtt atttatgaag gtgacgattt tgagcttgaa
     4741 attgtagatg gtgaaaagaa attcaaaaag catgatactc attggaaaaa tcaagacaat
     4801 ccaattgaag gggcttattg cattattgag gatatagatg gtaacactaa gctaacactg
     4861 atgacaaaaa aagagattga taaagcgtgg tctaagacaa agactggtgg agggacacaa
     4921 aaagaattcc ctcaggaaat ggccaaaaaa acagttatca acagagctgc taagtttttt
     4981 atcaatatca gtgatgacag tgacattttg gcagattcta ttaacaagac caccgcagat
     5041 gaatatattg acgatcgtca agtaaaagat gtaacggaaa cacagtcacc tgcacagaca
     5101 ctactcgata acatgaagca tgacgaggaa atgagcaaaa tcgaaacgat gcaaaatgaa
     5161 caattgatgc atgatccaga aacaggagaa atcattgatg cagaggttgt tgaggcggac
     5221 ctaaaggaat ctgatatgga ggagccattc taatgagcga aaatttaaca ctttttgaaa
     5281 atttaaatga cattaaacca gccgaacccg ctgagctgag ttttgatttt gagtttactc
     5341 cagccgaaat caaaatcaaa gggaaagaga agctcgaaga gattttagca gcctacgcta
     5401 aaaaatacga tggctacaca gtgacagccg aaacctttga agacgatgca aaggttagag
     5461 caaaactcaa tactttgcag aaagatatta ataactctgt aaaaacaaaa ctcgcagaat
     5521 acaataaccc tcttgatgat gttaagcagt gggttaactc aattattgag ccaattaaaa
     5581 aaattacaaa aacgattgat gagggtgtta aacactttga agaaatcgaa cgtcagaagc
     5641 gtgcaaatac aatcaaagaa acctttgagg ctgctattgc tgaaacaggt gctgatattg
     5701 atatccgctt gttcgaatct aactttgacg atatgtcggc taaaggatat tttatggctg
     5761 acaacgtccg cgtcaatacc gctaccaaaa aggccattaa caaattggtt gctgaagaag
     5821 tagcaaaaaa acaggaacat gagcaggcgc ttatccaaat ttcagaagct gctgccaaag
     5881 cggattttgg accagctatc tatatcaaac gatttgaaaa tggcgcacaa ctggcagata
     5941 tcttacaagc aatcgctgac gataaactgc ttgctgacaa ggtgcgcgaa gaagaaaaac
     6001 gcaaagcaga actatctaag cgagtagaag aaatgacagc cctggcacaa cgtgaagggt
     6061 tgcaaccagg caaatatgta aaattgcttg aagatggcaa gtctgcttta gtcgtttttg
     6121 aaactctgat ggacgattct aaaaaaatgc aggccaagat agcacaaaaa aacgcagaag
     6181 cgcatcagca acaaatagaa cagaccgaat atatgtctga ggcctcaaat tcgggggtaa
     6241 acgagcttga aacagacaag gtgataaata atatcatcaa acaagaaaat gccttagaag
     6301 ccaaaataga accgaataag agcgtcacaa aatggcaagg tgattttaaa ataactttcc
     6361 cggattcaga aacagctaaa ctatttggcg ggcaaggcgg attatacgaa aagcatggcg
     6421 tgattgttga aaaattaggt gaatgggtga agattaatga ctaaattaac cgaagaaaat
     6481 tattatcaag accgagaatg gttgtctaac tcaagattta aggctttcct tgattgtgag
     6541 gctaaagctt tagctgtcga aaacaacgag tgggaagata ccagagatga gacaccgctt
     6601 ttggttggta actaccttca cagctatttc gaaagtcctg aagctcatga gaaattcaaa
     6661 gccgagaatg gagctaagat gatttccagt cgtggagtta caaaagggga actcaaaaaa
     6721 gagtacaaag tagcgcaaaa catgattgaa acgctagaaa ctgatgagat atttaatctc
     6781 atgtaccatg gccaatctgg tgataatgtt ttgaaagaaa tgatcatata cggggaaatc
     6841 ttaggcataa aagttaaagg aaaagttgat tcaatcaatt taacaaaagg ttatttttgt
     6901 gacttaaaaa cgatgaaaag catacacagc gacgaatgga gtaatgactt gcgtaagcgt
     6961 gtacctggtg tagcagctaa cattatcggg tttaaatacc atatccagat ggggctctat
     7021 caagaattac tcagacagat gactggaaaa acgcttcaac cgctaatcat tgcaatcagt
     7081 aaagagaatg taccagataa ggaactcatc gaacttggcc aaacgtggct agatgaaggg
     7141 ttgcaacttt ttgaaaacaa tgtggagcat gtgcacgaag tcatcattgg taaagctgaa
     7201 gctaagtcgt gtggacgttg tgattattgt cgaagtcaga aaaagcttaa tagggtggtt
     7261 gatctcgatg atttgattgc aggaattttt taggagatct tattgtattg caaagtgatg
     7321 ctcggccttt gcagcaacaa atattttccg agcgagaaag gaaaattgca atatcgtcaa
     7381 gttaacagga ttgatgatat aaagagttgc tacactcgtc cttgctaatg ctcacacaca
     7441 attttagggc gagtgtggat tttaaaaagg tgaaaatatg gaacaaatca aaattacagg
     7501 aactgacaca atattaattt tagatagagt agatagggcc tttgtcattg agggtaatct
     7561 agctgaaaga tggcgtttta ctagcaagtt tataaagatt gacgatgagc tatcgctgga
     7621 cgaggacggc gaattgtttg agatagttta tgacttaatg ctagaagcaa aacctcacaa
     7681 cgtgattaat ctaacatcat catattttgc taaagaacat aagaaagaca cagatgaaat
     7741 cataaaagta tttgctttta tcgaagataa caagaagaat atttttgaaa cccttggcat
     7801 tcgcggggtg cttgaatgag caatctagta ttatcgctag acatctcaac atctggtaca
     7861 ggttgggcct tatttaaagg ctcagacctt atccagagcg gtgtcttaaa acataagagc
     7921 gactcttatt ttgaacgtgg acgctatatg gctagcaaat taaggttgat ccagtcacga
     7981 gcattaaaaa aatacgattg ctcctttagc acaatcgcag tcgaaaaaaa ctcggttatg
     8041 ggtccaaatc aacaatccat gcttaaaatc ggcattgtaa ctggtatcat cttaggacga
     8101 ttgatagctg ataatgtcgt atttatcaat gtctcaactt ggcgaaagca ctggaagttt
     8161 agctacaaag accgctcaaa aaaagcaatg aaagcacagt caaaggctaa ggctgctgaa
     8221 aactttggca aaatagtcaa agatgatgag gcagatgccg tcttgattgg tgcatactat
     8281 gtcaatcaag gctatcttga tggattggag acacatgact actactaaaa aacacgttgt
     8341 gaggatttac aacaaaggta ttacagcaac ccacgcagtt actgataaaa atttatttac
     8401 agagtataca tttgcgacgc agcaagatgc cgagaattat atcagagact tagagctaaa
     8461 cggatctaag tgtgcccttt gagtattatg agaggagatt tgcaaaatga tagacaccga
     8521 tacacttgca gcagtacggg aggctgatca tgactaaaaa cgacttttta acaggttttg
     8581 tacttatact tttagctgct tgcatttttg cagcaggatt tgtgattgga tctgactgta
     8641 gtagcgagca ctacgagcaa caaatgacag gcttgcgtat gcagcttgtt aacacgcagc
     8701 agcagcttaa gcgtgcgagt gaggatagag caaggcggac taaaaggatt gcggatctga
     8761 ccgggaatgg aggatagggt atgatcgacg aaatcgaact cgacctacaa aaaccagaaa
     8821 tcccacagtt tgtcgctgac tacatagatg atatgcacaa aaacgcacgt acattgagat
     8881 acgcttttaa atacatggaa agtaacataa aaatgcacaa atggtgtgtt tttgaaaggc
     8941 aagaaacgtt tgttaatgct tttttatacg gctacacaat aaaaaaagaa aagctgtata
     9001 ttgttgagat ccctaatcct aatagtggca tagaacacaa acatattgca ctagcaaggt
     9061 tagcgaatgg aaaacttgga ttttcagaga tcatagatac tgatttttat tcaagagaag
     9121 atgtccgact caccgagtca gaaatccgca aagattttga ttgggcatgg agagaggggt
     9181 ttgctaaaga ggtgacggaa tgagcagaga taaaaccaga atcaggaaca ttgtgaagtc
     9241 catgaaacag ttaggtgcta gcgaagaaga gacagacgaa tacatgtatc tatgcgtgtt
     9301 taaaaagcct cacgtcatag ctcaaatccg taaaaaggct aagattttca gaggcgaagg
     9361 gtggtaacag atggcatatt tacgagaaga aagagaaaca gttattcatt acgacgaatt
     9421 ggatgactgc tggacttttg aaactaacgt ccgtaggcat attacgaaaa tagaaaaacg
     9481 catcgaactg tacgagattc tctcagagga attcgatgac cgaggaaggc gtatctatat
     9541 ctgtgcgaaa atgaagacag gaactgtcag tccctttgcg aaaccaccaa gaaggaaata
     9601 gctatagaat cgattttaag cttcaaaaac atggcaagaa cgcacttctg ggaacgtgaa
     9661 acacctagct aatataaatg taccctagaa caatttaaat cgaaaaaatg attagctaca
     9721 taggttttaa tcggcttatg tggcatagac cgaaattaaa cacagaagga tgtgatgaca
     9781 atctccttac acccaaaaaa tctaacgctg gttatcggtc accagctatt atccaaggcg
     9841 ctaatactga catcgtgtgc ctgagctggc ttataaaaaa cgaaagagag ggcttttctc
     9901 cacacaaaaa gacgtccatg cgaacgcctc cttggttata tctgttaaca ccattatacc
     9961 acactgaggg ggctttcatg acgttttttc ctgagattga tatccaaaaa acaaaatcca
    10021 atgccaagcg taaattgaaa gagtatccac gctggcggcg gatagctaac gatgtagata
    10081 ctcaaaaagt tacagctact tactcatttg agccaaggca acctcatgga gtccatagca
    10141 agcctgtaga gaggttagca cttaatcgtg tgtcagcgga gcaggagtta gatgcgattg
    10201 agcaagctgt cagcatgata ctagagccag agaggcgcag gattttgtac gataaatact
    10261 tatcacctta taaaaaagcg gacaaggtta tttatacaga attgtgtatg tcagagagct
    10321 tttattatga tacgctcgat atcgctttat tagcttttgc agagctatat agagaggggt
    10381 ctctgattgt cgagcaagga gtttttagct agtttttata cagtaatata atagtttttg
    10441 tacaaaatag cgtgttaata tagtatcata gcaaaataac aaaaagagat aaccatttta
    10501 ccaattgact atttatttag tcgccaactt taactacgat caaacttgtt attttgaagg
    10561 tacatgggac gtgcaggttc gaatcctgcc gtctcaatac cagctatttc caaaatggaa
    10621 acagttggaa aagacaaacc ccccattcct ttaaaggcag atacgttctg atatggggct
    10681 ttttatgatt aactgcaagt aaaacaaggg tcgcaacctt gcttgtggtt agtagaccta
    10741 gtggtcgttt atgcacgttc gattcgtgca aggtctgttg ggttgattgc aataatcctt
    10801 ttgtggacgc acaacaaaaa tgtgatgtaa gtcacggcta aggtttgggc ggcgatagaa
    10861 tagatgcgca actatcgttg ggtcacgtct cagagtttgc atagttaata ttaaccgatg
    10921 ggcacaccct gcgtcagtgg gttgtttatg gatagcttag caaaggggtt aatgcgacca
    10981 actgtttagt ttggtaggcg tgagttcgaa tctcacacta ttctttcagg aacatgaacc
    11041 gtgattggaa aacggtagag gtagcgcctt gataattgga ttgtcgacgg tctgattata
    11101 tgtgtcggtt caattccgac tgttcctgtt ctagtcacca attgtggtgg ctttttatta
    11161 tgtcacgagg aggtgatgga aaattgctaa gttaactata aaacaacaaa aatttattga
    11221 tgagtacatc atctgtggaa atgcgacaga agccgctctt aaggcgggtt atagcaaaaa
    11281 aacggctggg caaatcggtg agcagaactt gaaaaaactt gaaataaaat ctgccatcaa
    11341 cgaacggcta aaacaactcg aaagcagtaa aatagctagt gcaatcgaga tcctacaagt
    11401 tcttactgcc gttcttcggc aggatttgac ggaggaggtt gttaccctta atcctgtaac
    11461 aggtgagtac gttactatgc agaaaaaacc tagcatcgca gaagtcataa aagctgctgg
    11521 tgagttattg aaacgttatc ctatccaaga acaaattgaa aaaatcaagc aagaaaacga
    11581 gttgttacgc cttaaaattg aaaccgtcaa aggcgccaag cctgataccc atttgatgga
    11641 aaaactgctg gaggtaatcg aagatggcgg ttaggataaa aaagttatcc acaaaacaaa
    11701 aagacatcat tagacgccct tttaactacg aattagaggt caatgaggga acacccagaa
    11761 gtggaaagac caccgctggg cattttcgtt atgctaggta tctgattgag tcagaagatg
    11821 aaaatcatct tgtgactgct tataatcaag aacaagctta tcgtttgttt attgatggag
    11881 acggtacagg gctgatgcac atctttgacg ggaactgcga aatcaaacat gatgagcgag
    11941 gagatcacct gcttgtaaca acaccaaaag gtaataaaag ggtttattac aagggtggag
    12001 gtaaagttaa ctcagtcggt gctattacag gtatgtctct aggctcagtg gtcttttgtg
    12061 agattaatct actgcatatg gattttatcc aggagtgttt taggcgtacc tgggcggcta
    12121 aactgcgtta tcacttagca gaccttaacc ctcctgcgcc acagcaccct gttattaaag
    12181 acgtttttga cgtccaaaat accagatgga cgcattggac catggacgat aatccaatat
    12241 taactgcgga gcgcaagcaa aacattatca atagcctcaa aaaaaatcct tatctttata
    12301 aacgagatgt actcgggcag cgggtgatgc ctcaaggtgt tatttatggt ctttttgaca
    12361 tggaaaaaaa tgttctagac actttgattg gcgagccagt ggagatgtat ttctgtgcag
    12421 atggtgggca atctgatgcc acatctatgt cttgcaacat cgtaacaaga gttagagata
    12481 atggcaagat aagttttagg cttaatcgga cagcgcacta ctatcatagt ggagcagata
    12541 ctggtcaggt caaagccatg tcaacatacg ccagagaact taaggctttc attgactggt
    12601 gtgttaaaaa ataccaactt cggtactctg atgtctttat tgaccctgcg tgtaaggctt
    12661 tgcgcgagga attacatgcc attggtattc tgacgactgg agcgccgaac aacgctcacg
    12721 acgtaaacag taaggcgaaa ggtatcgaag ttgggataga acgtggccag actttgattt
    12781 cagacggtga tttttatcta gtaaatcaca aagaggaaaa atatgatcat tatcatttcc
    12841 tgaaggaatt agggctttat agccgcgatg ataaaggcaa accaatagac gcaaacaacc
    12901 actcaatgga cgaatttagg tactcggtca atgtttttgt gggacgatac aaaatgaaat
    12961 aggaggtagt catgtttaga aacctctgga ctaaaataaa aggggtgatg caaaaaatgg
    13021 gattgataaa aggtttgaaa gatttgaacc tgcaccgcga aattgaactg tctgataagc
    13081 attatgatag tatccaaatt tggaaagagt tgtatcaagg ctatcacgat aaaatacacg
    13141 attactatga gaaatctatc ttagatggtc gtaaaaagaa gaagcgtttg actttgaata
    13201 tgcctaaagt tgtgacctca gagcttgcta cattgatttt taatgaaaaa tgtgaaatta
    13261 acattggttc tgaaaatgag agtttgacaa agctcatcac tgaaacgtta gagaaaaata
    13321 attttactca ggagtttcaa cgcttcttag aatatagttt cgccttggga ggtatggcaa
    13381 tcaaagcata tctcaaaaag gacggtacta tcggtcttaa ttttgtacaa gcggatagtt
    13441 ttattcccat ttcgtgggat aatgctggga ttagcgaagc cgtatttgtt gatacgcagc
    13501 atcgtggaaa atacaagtac acgcatttgg agtggcatac ttgggaaagt gagttgtatg
    13561 tagttgctca cgagttattt agaactgaca agtcaaatga tgatgttggc attcgcgtac
    13621 cgataacaga gatttatcca gatttaaaat cacaagtagt catcgaaaaa ctatcaagac
    13681 cgctatttgt ttacctcaaa cctaattcgg caaacaacat tgatctatca agtccgctag
    13741 ggatttcaat ctatcacaat tcgtttgata ccttgcgagc gattgatatt gcctacgata
    13801 gctttgagcg tgagtttcga cttggccgta agaggatatt ggttccagcg actgccattc
    13861 gtactgtagt ggatagcgag gggaatttcc accgctattt tgacgcaaca gacgaaacat
    13921 atgaggcttt ccacacaggt gaagacagca aaattcaaga tatcaaagat attagtgttg
    13981 aattgcgagt tgatgaacat attgcagcta ttaacgcact gttgaactta cttagtatgc
    14041 agattggctt tagcccaggt tctttcagtt tcgatggagt atcgggtgtc aagacagcca
    14101 ccgaggttat ctctgagaat tctaagacat tccgcacgaa gcaatctcat gaaacgatgg
    14161 tagaagcaac attgaaaaat cttgttgcga ttatcgttga ttttggggat ctttatggtt
    14221 tgatcgaggg tgagagtaag tataatgtaa ctgtaacgtt tgacgactct attgcgcagg
    14281 acagaaccca ggacgctcag tattatatag ggttggtcgc agctgggtta atcagcaaga
    14341 aaaaagctat gatgaagctg tttaatctgt cagaagaaga tgcagagttg gaaatccaaa
    14401 ctatccacga ggaaagccgg acaacaaacg atatgtcaat tgatttattt ggtttggacg
    14461 gtgatgctta gtggattatg atactcatat ccagctgtct tttgacttaa tagagcttta
    14521 ttctgatgtc gaacgtgaat tgttgacgtc aataggtcgc aggtttgcaa aacactatga
    14581 cgaaatggta gctggcgaca tcatggattg gcaaattagg caattactcg aagttggaga
    14641 gctgagaaaa gagcacatcg aaatcatgcg aaaaagtgca cgcgtgagtc gtgagcgtat
    14701 gattgagatg ctgacggagg caggttatac ctccgcagga aggtatgagg atttttttaa
    14761 agaggcatac gttaaaggtt taatcaagct caatccatct gctgcagaca acagcatgag
    14821 gttgttgcga gtgttaaata cttacatcaa tcaagctgag gacacactta atcttgtcaa
    14881 tacgaccatg ttacagtctg gccaagatac ttttttagat acagtcaatc aagttgttgc
    14941 ttatgtttct acaggtatca agaccccaca agttgctatg cgtgacgctc taaaaaatgc
    15001 tggtcaaaag ggccttacag tctttcgtgc taaaaatggc gcccagtggt caacggagac
    15061 ttatctcaat atgatcactc ggacgatgaa ctctaacatt tctaacgcta tggaagatga
    15121 gcgtaggcat gagtatggtg ttgattacat cgaggtatct agccatgctg gcgcacgtcc
    15181 aaggtgtgct ccttatcaag gtcggatata ttacgatggt gtcggagatg atccgctaga
    15241 gaaatacccg cacttctcag agacttctta tggcgaagct gctggattgt ttggcgttaa
    15301 ttgcggtcat cataaatatc cttacgtccc aggtatgagt aaacagacct ttttccctta
    15361 cagtaaaagc gaaaacgata aaacctatgc agagtcgcag gtacaacgta aattagaacg
    15421 ggaagttaag cagctgaaac gggaacgagc aattctaact gctgcgaagg acaaagaggg
    15481 ggctaaatta gcttctcaac gcttggagaa caagtggcag gaattgcgtc agtttactgc
    15541 tcaaacaggc agaacgagac gatacgaccg cgagaaatcg ctaaatacta ttttgtctga
    15601 ggacaagaaa aaagccattg tcaaagataa tttgaaaatc agagatgagt atcgagcgat
    15661 taagaaagct atccctgaag tagctcctaa aaatcttgaa acctattatg atatgcgtta
    15721 taatggtggc aagatatacg aggatttagt tagggattac aaagactata taagatggtc
    15781 taaagctgaa tttcctacta aaaaatcttt tgaagggcat attgatagtc acttaaaaga
    15841 gtttccagga ttgactggta aacaatatca gaaaaaggct gctgacttat tatctagacc
    15901 gataactgat aatattttag gttatgatac agattctaga cgtgttaggt atgacttaga
    15961 aaataacatt tttgctttag ggcgcgttaa acaaggtacg attacgacta tgctgaaacc
    16021 aaaggaaggg gttgattact ttgacaatga ctggaaaaga gagtttgata atcttaaatg
    16081 atttagaata tgtccattgt cctgtttgtg gaactttgac cgaggtttat gatatttgcg
    16141 atacttgtaa atggcagaat accggtgaga caaatattga tggcggtcct aattatatta
    16201 cacttgagga agcacgacga aggtgggcaa atggtgaacc tttgcgcaac ttttttaaag
    16261 accaataata caagcactgt aacagtgctt tttttgtact caaaaaagga gagagtaaaa
    16321 tgaacaaacg aattgaaaag aagcgtcgca cacaaatgat gttagacaga atcttgcgca
    16381 ttgtagaatt gatgtcgcaa gcaactgacg acaactttgc tatcttggaa aagcgcttag
    16441 aaaaagctga aaaacgtaac gaagagctta tggaaatcat cttagtaaac gttaaagagg
    16501 taaataaccg ctttgacgag ctagaaatct gccagaagat tgttgaagat gatgtcgcag
    16561 agctcaaaaa agctaagaaa aaaggctggt tcagccggaa ataacttaat cgtgtcgaat
    16621 tcgatgcggt tttattttgc cctgccgcat ggcgataaac taggtaaaaa taaaagaaag
    16681 aggtctaaaa tggctgttat tatcgtacaa acacgaggcg gagatattga agttcccacc
    16741 ccattaccag caatgcaagc taataaagcg attcaaagtc aattattcga taaggagctg
    16801 acttttttat gcgtggataa tcatgctttt gctaaaactg aggttttaca cgttttggtc
    16861 gaaacagaag aagatgaaga attaccacag tcaaaacata aggaggaaga aacatgctac
    16921 atggattaaa acaccgtttg tttaaactag ccccagatac tggagcaggc ggaggcgctg
    16981 aagttactag cgagactaac gctgaagctg gacgagttga gcaaacagta tcgcaacaac
    17041 aagctgatcc ggttgatact gaggcaatca aaaatcaagc aattaatgag gttctaagtc
    17101 aactaggtgt ttcttcggta gaagatgcca aagcaaatct agcttcttgg aatgaatatc
    17161 aagaaggtca gaaaacagag tttcaaaaaa ttcaagatag tttgactgtg gctaataact
    17221 ctttggctga gcgcgacact atgattgcta gcttacaagc tcagttagct gctgctcaaa
    17281 tgggagtgcc tgcggaaaac acctccgatg ttatcacttt ggccaatagt ttggtccacg
    17341 ataaaacaga catcaatgca gcgattacta ccgtacttga gaaatatcct catttcaaag
    17401 gaggtgatgc cgatgtagct gataaaccta actttgtgac tcaaactcag agtcaaacgg
    17461 aaacgacgga agacgctttt tttaaagcgt taggactaac aattaaggag gactaatatg
    17521 tcaatcaatt atattactaa acatgaagga atattcgaaa agaaactaat gcaaggcgct
    17581 ttgacgtcta acttagagac accaaaagtc aactggttag gtgcaaagtc ttttgagcta
    17641 ccaaccatct cggtgactgg ctataaggcg cacacacgct caaaagggta taacgcaggt
    17701 actgtatcta acgataaaaa tacttatacg ctcggctttg atcgtgacgt agagtttttt
    17761 gtggataagg cagacgtcga tgagactaac caagagctgt ctatggctaa catctcaaac
    17821 acttttatca cagagcatgc aacgccagaa gttgacgctt atcgcttttc gaagattgcc
    17881 acaaatgcga tcgataatag ccattttaag caggaagatg actactctac tactaatgtt
    17941 tatgagcgct taaaagctgc tattttgcct attcgcaagt acggagctgg caatatcatt
    18001 atctatgtct ccagtgagat tatggacttt ttggagcgct caaaggactt tacacgctca
    18061 atcgcgacaa catcaccgca agggattgat actcgtgtga catctcttga cggagtgcag
    18121 ctcatagagg tttgggacga tgcccgcttt aagactaaat ttgattttac gacaggcttt
    18181 gtcaaagatg gcagcggtaa agacattaac tttttgattg tggccaagcc tgcggttatt
    18241 gcaaaagcta aatttaactc tatttatctt tttgcaccag gtcagcacac cgaaggggac
    18301 gggtatctat atcaaaatcg cttgtatcac gacctttttg tgcttaaatc taaacaagat
    18361 ggggtttatg tatcccataa atcagcttag gaggttaacg atgaaaacat acgagaagga
    18421 caatcaagtc tataaagtac aagaaggcag cgagctggaa attcagctga ttgccgacgg
    18481 ctttaaagaa attattgaag caaacgaaaa ggaaactgat atcactaaaa tgaagcttga
    18541 taagctaaag gcttatgctg aaaatgaagg cattataatt cctgaagata ttaagaaaaa
    18601 agaagatgtt ttagctttta ttaaggaaca gcagcagaga ggtgagtagt gatgctcacc
    18661 tttgattttt acaataaggg atattgtggc tcacagctga atgaagaaaa gttcggggag
    18721 ctgtcaaaac gtgctgagcg taaaattttg gcacttattg gcttgaaaaa ggagcaagtg
    18781 aagaatttgc cacttgatat tttagaggcg gtaaaaatgg ctgtctgcgc ccaaattgag
    18841 tatcttaacg caataggcgt tgaaagtgct atcggagtaa cctctgtaac ccaagctaaa
    18901 gtcggcaatt ttagttacac agacggaaag aaagcgactg tatcagctag tgttggctct
    18961 gttggtgtta gccctgacgt gctagactat ctgcttccga gtggattgtt atacaagggg
    19021 gtgaatacga gatggtaaaa gaagtcaaac ctatccctaa agagttatta gttgacacag
    19081 ttacttatct agcagttggc aacaaagaca gctggggagc agaaacggta gtatctacag
    19141 aattgtcaca ggtgttagta caacctagaa gcagtatcca acgtgggcaa caaaacgaga
    19201 gtaatagcta cgagttgtta ctcttttttg attgtgtaaa ctcgttacca gtagatcatc
    19261 agtttaaggt tgacgacaaa attagttatc taggaaaaga gtatcgtatc gcaagtgttg
    19321 aggtactaaa agcttttgac cagtcgccac atcactatga ggtgatgcta gaatgatagg
    19381 ttttaaggtt gaagtcatct ttaacgctag taaattgatt gccaagagtg aagcatctgc
    19441 aaagacagct cgctttgctt taagtggtca aatcaaaaag gatagtgaca agtatattcc
    19501 tgctcgtgag tggaatctgc gagatagcgg aagagtaact gaacgctcag tatcttggca
    19561 tacaccgtac gctagacgac tctactacaa tcctcagtat aactttagca aggataagaa
    19621 tccgaatgca caaggcaagt ggtttgaggt tgctaaagca aatcatgcag agcattggta
    19681 tgagctaaca aagaaagcct atggtgctga gtttagagga gattaatcat gacatttatt
    19741 gattttttgc tcagaaaagt tcaagaagtg agcggagcgg aaccggtcct tggcattatg
    19801 gggaatagtg ataaggttgc tattatccct atggctggaa attttgacaa tcgagctctt
    19861 gacgaaagta agattaggat ttttactttc caagttttgg ccaagagtaa aaaacagcag
    19921 gaagcttttt tgacaacaga aaacttggtc aatggtctag acggtctatc aaatgagccg
    19981 tttactggag gatatctcat taagctggag tgtacgacga ccactaactt tgttgaaaaa
    20041 gatagtgaca aaaattattt atatacagct cttttcagag cagaattagg aggataagaa
    20101 atggcagcag ataagccaac tttttattta caatccgagc ataagctcga aatttcagaa
    20161 gatggaaaaa cttggatgcg actagcaggt ggtatcagtg aattagaacc agacggaaat
    20221 gaagaagtat cacaagatgc ttatcttgac ggctctgaat ctgatgttac aggaggtcag
    20281 ctagtactag ccttaactgg acatcgtcta gtaggagata aagctcaaga ctggatctat
    20341 gcacgtcaat tccgatatgg gggcaaacgt cgtggtttta cgcgttggac attgccagga
    20401 ggaaaaacac agtttacctt tgcctctacg tttgcaaata tcaaaggtcc atcaggagcg
    20461 gctaacggta aaggtgaaat tgaatttgaa atccattcga acgaaacact tgtacctaat
    20521 aaagtagttg tagaagtcac taagacaaac aaagaacttg cgtctgaagc acttggttta
    20581 gaacgtcaag agcgataagt agaaaggata gtcagcaatg gtgagacagt ttgaatttaa
    20641 gaaaacggtt gaagaaattg agattgcagg ggaaatctac ttactgcctc ttgatgatga
    20701 taacctctta cgtatccaac gtgactttat tagttacgga aaagagatcg aagaactcca
    20761 aaaagttgag gtagaaaaag gagatccaga cgatctggcg gataatcata agcaacagct
    20821 tttagtaatg aaaaaggtca tcgagtcacc atttggagaa gggagttttg agaaacttta
    20881 cgaagcatca gggcactctt taatgaatat ggttgactta ttggattatc ttgttgagtt
    20941 agtcgctgaa aaagttgagc aaaataaggc tcgtgccact aaagcaaaag agaagtatta
    21001 ctcctcgaag cgcaagaaaa agtaggtagc ttatgaagtt gacagaaaca tatgaagttc
    21061 ttgctgatgc ttttgaattt ggcggtcata tcgtaactgt tgacttggct tttgatgtcg
    21121 tgttgcgagt catggagctt cttgccgacg cagaagtcaa tgactacgct aaaattgtct
    21181 ggactttgga tatgctcttg ccatattttg atcgtacgga gttaagtttt gatgaagaat
    21241 ttgaaatttt cgaatatatc ctaaagacgt ttatctatga acaagaagac ggagaagatg
    21301 acagtttagg aggaatgtca caaacgaaaa caatgcattt tgaaaaggat gcagagttaa
    21361 tctttgcgtc cttttttcaa agttatcatc ttgacctatt tgaacaacag ggaaaattgc
    21421 actggcgaaa atttatgtca ctgctcatga atctgcataa agacactcct tttaaggaag
    21481 ttgtcagcta tcgtgtcatg aaagtgccta ataaagatga agcatcggaa gagtatatca
    21541 aacacgtcaa gaagatgaag cgtatctatt cgctagaaga cgaatctgag catcaagcgc
    21601 taaatgatga caagctttca gcgttagcag caaggtttgg aggtgagtag atggcagatg
    21661 gtagtgttat tattgatacc ctgctaaaga ctgagaaatt taaccaaggt gtagggaaac
    21721 tacaaggtaa attagctgga ttaggatcaa agttgaccag cattggtacc ggtctaactc
    21781 taggcttaac tgctcctatt gtaggaatcg gagcggcatc gctcagcacg tttactacat
    21841 ttgaaagtca aatgaatcgt gttaaggcga tttctggagc aacagcaagt gagttcagaa
    21901 aactagaaga ccaggctatc aaacttggag cttcctctgt ttttagtgcg acagaagtag
    21961 cacaagctca agaaatgatg gcttctgcag gttttaaagt cgtcgatatc ttaaaagcaa
    22021 tgccgggtgt tatgtctcta gctgctgtat ctggtgggga tatggcatta gcaagcgagg
    22081 cagccgcaac agctgtcaat atgtttggac ttgaagctaa agacgcagcc catgttgcag
    22141 atgtttttgc acaagctgct gcggatacta acgcagaagt tggagatatg gcagaagccc
    22201 taaaatacgc cggacctgtt gctggggctt tagggattag cttggaagaa accgcggcag
    22261 caattggtat catgtctaat gcaggcatta aagggtcaca agcaggaaca actttgagga
    22321 caagcctttc acgacttacg gatccaacta aaaagatgcg aggaatcatg tccgaattag
    22381 gacttgaatt tttcgatgtt aatggaaaaa tgaagtcctt atctggtatt accaaagaac
    22441 ttcaaaccaa aatgggtgat ttaactgata gtcaaaagag tgcagctatc tctactttgt
    22501 ttggtaaaga agcaatgtct ggaatgcttg ccctagttaa ttctgctcct ggcgcattag
    22561 acaagcaaac acaagcactt atcaattcaa atggtgctgc taaagaaatg gcagacacca
    22621 tgaatagtgg tgtcaaggga tcgattgagg agcttaaagg ttcgcttgag actgctggaa
    22681 tctccatagg taaaatattg gcgccagccc taacgtcggt tatcggggcg ataacaagcc
    22741 ttgtgaattg gttcaataac ctaagtccga caatgcaaaa cgtggtagtt gtactcggaa
    22801 gtttacttgc tgccattgga ccggttgtcc ttattatagg ggttgttact actcagatag
    22861 cagctttcca gcaaggcgtc ggactagtct ttaatgctgt caaaggatta caagctgctt
    22921 ttgccttttt gacgagtcct atagggttag tcatcgtagc cataggtgca ctaattgccg
    22981 tatttgttta tttgtggaat acaaacgaac aatttagaac gaagatcatt gagatttgga
    23041 cggctatttc gaacttttta cagcccatca tacaatttat tggtaatttc ataagggaaa
    23101 cgtggactca attagctact ttttggaacg aaaatcaagc aactattatg acaatagccc
    23161 agacaacttg gtcatttatc cagacgatat ttacaacagc aattgaaatg ataaaattgg
    23221 ccgttagtgt ttttttaggg ttattgcaat caacgtggtc tgtaactttt aattctctta
    23281 aggttatcgc acaggtcgca tgggctttta tttccaatgt tttcaaggga agtttagggt
    23341 ccatacttgc ggttgcatct gctatatttg agcaaattaa atcaacgatt gatcttgcga
    23401 tgaaaattat tcaaaatatc atcaaaatca tactatccgc gatagaaggt gattgggacg
    23461 gtgtattaga aggtatcaaa ggaattgttt ccgcatttgg agattttatt caatcaactt
    23521 tctcaaatat gatggatact gctaaacgct tagtcggagc tggaatagat accgtaaaag
    23581 gaattttcga ttctttgtgg aatattgact tgttcggagc cggtcaagcg attattaatg
    23641 gattcttaaa tggtttgcgg tctatgtggg gagctgtcac agatttcgtt ggcggtattg
    23701 caagctggat tgcagcaaac aaaggtccca tctcatatga tagggtacta ttgaagccgc
    23761 atggaaaagc tattatggac ggactcggta atagcatgaa aactaacttt aaggacattc
    23821 agaaagatgt ttctggcatg gctgacgatt taacaagaag ttttcaaatc aaaaggttca
    23881 acggtttttt gccagaaaag tatactacta agcttgatga gcttaaaaaa tatgcgcaag
    23941 ccacgcttgg cggaatgatt ttagccccta acatggcagt tcaaccgaca gtcgttgtta
    24001 acatcagcaa tgaagcagat agcgatatca tcaggcaaaa agtcaatgct aagaatgcac
    24061 aagatgctat tattaatcag ttattcaaga aagggtaaaa catgttcagt atagagtttt
    24121 tagacggaga gcgactaagc gccgatgaac gaggatggaa agttaaagag atgtcctcat
    24181 caggacttga acaaaacgtc gttagcgagt ctcctaaaat gcgttctggt cgccttgttt
    24241 atggtcttta tcatggcatc aaaacttatc aacttgtttt tacaaaaatc attaaagata
    24301 cccttgatta tagccgttta gtagatgaag ttaattacta ttttttacgt gatgaaccat
    24361 actatcttta ccgcgacttt agaaagaaag ctgatcgggt ggacttgccg aagaagcggg
    24421 cgaaggtgtt tactaagtca atcgaccatc aaaaaaatgg gcttaaagtt gaatttacag
    24481 ctaagctgga atcttatgaa ctaccctacg aagaagatac tgaggttcag cgggtcactt
    24541 ggacggcaac acattcatgg cacaataagg gagggcatcg ccttgaccct cgttattgcc
    24601 caatgaagat gaccataaca gtatcaggtt caggagctga acttaaggtg ctatttaacg
    24661 gtcagcctta tttttggtat aaaaaatcag ttaaacaagg ggatatcttt atcattgatg
    24721 ggacggacgt tgaaaaaaat agatacaatt gttttgaaga ttgccataag caaacctctt
    24781 ttttaaaaac aggaaataac agaatagata ttcaaggagc ttcgtgtgaa gctctttttg
    24841 aatatagact actgtatttg taggagggtt agtatgcagg taaaaacaaa gcaaggtgtt
    24901 ttttatgtta acgcagacta caccgtcgtc gaaaaacaag gtgactatcc taagctaact
    24961 tgtactattc ctattaaggg aaatgagact tggatagcag attgccaaga acttgaccgc
    25021 ttatacccag ctggggaaca agatgaattt attattatca atcctattaa agtcactaag
    25081 gggagttcgt atgatttgga aattacagcg ataggagcct ttcattttga atttgtaaag
    25141 gctcgtctat atgaagaact accagaacga atgtatactt tagattactt gctcgatctc
    25201 ctgtttaaag acagccgatt cagttataag ctacaaggtg attattctac tagaaggttc
    25261 agtggcttcg gagatgataa caaactgact ttattccatc atttaatgga acgatttcaa
    25321 acagaattta aagttgttgg caaggtcgtt ttagttaaca caaaagtagg taaagataca
    25381 ggatttcagt tccgctatct tagaaatatc aaggatacaa agtactcggt agacgtaact
    25441 aacctgatga catacgttaa aggatatgga gcctggtttg atgaaaatga ccattcaaag
    25501 ggaagattaa ttgttgatta tgagagcccc ttatccaaag agtatggcaa acttgatggt
    25561 aagcccgttg ttgatgaacg aatgagttta aaagaaagtc ttatcaaaaa atgtaagcta
    25621 gccgtagatc gctctgtatc tgtcagctta acaacgactt tagtctcttt aaaacaacag
    25681 gattatcaag gtgcggcgag aataggagac tctatttggt ttattgacga acgtatatct
    25741 attgaaaaaa agattcggtt cagcgtagta acaacttact acaatgcata tgatgatatt
    25801 ttaaagcagg acgttacttt aggtgataaa gatacctact ctcgatatca aagtttagaa
    25861 aactcttctc aaacagagac aaatgatttt caaaaagcga tgagtagcaa acttgcagaa
    25921 gttcaagatg atgttaaaaa gacgcatatt ttagtatctg gcactactag gattttcttt
    25981 tctacagagt ttcctcagga taatcctaag ggaactataa aagaagatga cattttgtac
    26041 cgtaatcacg atgggacaac attgatgtac aggtggaatg gtgttcaatg ggaattagtc
    26101 ccgttggtaa acgatccaga tcgttggcgt gaggaactgg agaaacaaat ctctgaggct
    26161 gtcgaaaagc tcaaacaaga gcaaaaagta atcaaccaga gaaccgataa agagctcgaa
    26221 gagtttagag atacgctcaa aaacctatct ttaccagagg aagccattaa aaaaatcaca
    26281 gaggctatca aagttgatga tatcccgtcg attaaacagt catttgatga cttaaaaaat
    26341 aaagtcagcg agacaagcga gaccgcacga ttaaacgctg agattatcgg gacagatggc
    26401 aagacccgct acaacaaaaa tttgctagtc ggcgaccc
//
LOCUS       DARYNN010000030        25038 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.030, whole genome shotgun sequence.
ACCESSION   DARYNN010000030 DARYNN010000000
VERSION     DARYNN010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25038)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25038)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25038
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.030"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            310..2454
                     /gene="pnp"
                     /locus_tag="TVB59_001238"
     CDS             310..2454
                     /gene="pnp"
                     /locus_tag="TVB59_001238"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEL1010134.1"
                     /translation="MSKQTFTTTFAGKPLVVEVGQVAKRANGATVVRYGESTVLTAAV
                     MSKKMSTGDFFPLQVNYEEKMYAAGKFPGGWMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDEDASAPMAAMLGSSLALSISDIPFNGPIAGVQVAYVEGEFI
                     INPDKAQQEASLLELTVAGTKDAINMVESGAKELPEAIMLEALLVGHKAIQELIAFQE
                     EIVAAVGKEKAEVELLQVAADLQAEIIETYNADLQQAIQVEEKKAREAATEAVKERVI
                     AAYEERYAADEEHDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRRVDEIRPLAAEI
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGDTQIIDGLEPEYKKRFLHHYNFPQYSVGE
                     TGRYGAAGRREIGHGALGERALAQVLPSLEAFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGTNYTVLTDIQGLEDHFGDMDFKVAGTRQGITAL
                     QMDIKIEGITPQILEEALAQAKKARFEILDLIEATIAEPRPELAPTAPKIDTIKIDVD
                     KIKVVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIASLVREAKV
                     GEVYHAKVVRIEKFGAFVNLFDKTDALVHISEIAWSRTTNVSDVLEIGEEVDVKVIKV
                     DDKGRIDASMKALVPRPPKPEKSEAKKEGKHD"
     gene            2447..3199
                     /locus_tag="TVB59_001239"
     CDS             2447..3199
                     /locus_tag="TVB59_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SseB family protein"
                     /protein_id="HEL1010135.1"
                     /translation="MTNTNELDIRLRAFINAPDNFLDSVALVNAFHQYPVWAAKKPYA
                     IEIEGVRIFPVFTDKDDMATFKEEQKSAQAQYWVERSALTVLEEAVHAGAAGLGFNLK
                     KKGDFGNSTVFKSADMIQFMNNYTTILNTLMSDDNSAADTLDRLYLVPAFVYPKEEEH
                     YYDRLFPTMSTPEGKRYVPAFSNLQSFAKWYNQEEFGGLFRKSGGVILTWKIADIYQP
                     RNGNNDIDETFGVAIDPFDDQQILVDWSDIDT"
     gene            3211..3747
                     /gene="cysE"
                     /locus_tag="TVB59_001240"
     CDS             3211..3747
                     /gene="cysE"
                     /locus_tag="TVB59_001240"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEL1010136.1"
                     /translation="MGWWKDNIDIVKQLDPAARSTLEVILTYPGLKALAAHRLSHFLW
                     QHGFKLLARMHSQFWRFWTQIEIHPGARIASGVFIDHGAGLVIGETAIVEKGAMLYHG
                     VTLGGTGKDRGKRHPTVREGALISAHAQIIGPVEIGKSAKVGAAAVVLTDVPAGVTVV
                     GIPAQIVRVHEKKPSRQD"
     gene            3865..5208
                     /locus_tag="TVB59_001241"
     CDS             3865..5208
                     /locus_tag="TVB59_001241"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEL1010137.1"
                     /translation="MIKIYDTMTRSLREFVPITDKVVNMYVCGPTVYNYIHIGNARSA
                     VAFDTIRRYFEYAGYTVNYISNFTDVDDKIIKAAKESGVSPKELADRFIAAFMEDTKA
                     LGVKPATKNPRVMDYMDEIIAFIAALIKKGYAYESAGDIYFRVAKASNYARLANKTIA
                     DLEAGASGRTDTETALKEDPLDFALWKSAKLGEISWASPWSAGRPGWHIECSVMATEL
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTSKTFANYWMHNGFVNVDNEKMSKSLGNF
                     VTVHDLLKTVDGQTLRFFLATQHYRKPINFTEKAIHDAGVNLKYLKNTLQQPTVATAD
                     ASQLAAFITAFKAAMNDDFNTANGITVLFDMAKWINSGAYSEAVKSAFEEMLAVFGIV
                     FEAESLDTEIEQLIAERQEARANRDFARADAIRDQLAAQGIKLLDTKEGVRWIRG"
     gene            5201..5608
                     /locus_tag="TVB59_001242"
     CDS             5201..5608
                     /locus_tag="TVB59_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEL1010138.1"
                     /translation="MANSVDVNLINGIALAFVGDAVYSYYIRRHLIFQGQTKPNKLHY
                     LATKYVSAKAQASLIQAMLEAQLLTEKEKDIYKRGRNTNSHTKAKNADVVTYRMSTGF
                     EAIMGYLDMTGQTERLELLIQWCIKQVENSPQS"
     gene            5825..6613
                     /locus_tag="TVB59_001243"
     CDS             5825..6613
                     /locus_tag="TVB59_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010139.1"
                     /translation="MKPMRNVALVISAMLLLSSQAFVSAVAAQDNQPTIAVQAQAAAE
                     ANVSARMRSDQPVIEANIATSQPVSQSTEATILLKDAKGNAINSTAYTMQAGQSRFSV
                     WFDLTNLKVSDYSISVSVPDKEKAFSGSSAPIHFDGKPTKNTPETEQKNSNPVPANNQ
                     PKPAASGRVTSTEQPQNVPSATASANHMTRTNHRSDKVLKASSSNTPSAAKSIDSAEK
                     GKGMLSDSTAQDKEQKGFPWLLSSLIAITAAALLALVIKAVHRK"
     gene            6662..7408
                     /gene="rlmB"
                     /locus_tag="TVB59_001244"
     CDS             6662..7408
                     /gene="rlmB"
                     /locus_tag="TVB59_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEL1010140.1"
                     /translation="MKAKEINETKDIVYGVHAVTESLLANTGNKLYIQEDLCGKHVDH
                     IKDLATSKKVSISWTKKKALTEMTAGAVHQGFALRVSAFAYTELDELLELAQQEDNPL
                     LLILDGLTDPHNFGSILRTADATGVCGVIIPKHRAVGVTPVVAKTSTGAVEHVPIARV
                     TNLSQALDQLKANGFWVFGTDVTGTPSYKWNTSGKLALIIGNEGKGISANIKKQVDEM
                     ITIPMMGHVQSLNASVAAAILMYEVFRNKL"
     gene            7409..7927
                     /locus_tag="TVB59_001245"
     CDS             7409..7927
                     /locus_tag="TVB59_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HEL1010141.1"
                     /translation="MKKRLLLVDGYNMIAFWESTRQFFKTNQLDQARRILLNKLNNYA
                     HFDDSDIICVFDAQYVPGLRQRYDQYRISVIFTEEEETADSYIERTAAELNTALTMVE
                     VATSDLNEQWTIFSQGALRVTAKELEQRVNAVKSDLDKLSQDIDLKKPRLGPFDQGQL
                     NQLKDFMNRLDD"
     gene            8111..8971
                     /locus_tag="TVB59_001246"
     CDS             8111..8971
                     /locus_tag="TVB59_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL1010142.1"
                     /translation="MTFVLMTDSTADLDSFWAKEHNIDIVGLTVECDGKVYKTVGPDR
                     LTSDALLAMMKSGSQPKTSQINVGQFEEIFRHYAADNQALLYIAFSSVLSGTYQSAVM
                     ARELVLEDYPDAVIEIVDSLAAAGGEGYLTMLASEARDNGKSLLETKAIIEGILPRLR
                     TYFLVDDLFHLVRGGRLSKGSAFIGSLVNIKPLLWIDASGKLVPIAKIRGRKKAIKEI
                     ADRATKDIADSTVVVSYTSDQTGADDLREQLLAHEGISDVFMLPLGPVIAAHTGPDTL
                     AVFVIGKEKR"
     gene            9510..9956
                     /gene="rplM"
                     /locus_tag="TVB59_001247"
     CDS             9510..9956
                     /gene="rplM"
                     /locus_tag="TVB59_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEL1010143.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKVYYTHSMYPGGLKSITAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGGEHTHAAQQPEVLDISGLI"
     gene            9976..10368
                     /gene="rpsI"
                     /locus_tag="TVB59_001248"
     CDS             9976..10368
                     /gene="rpsI"
                     /locus_tag="TVB59_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEL1010144.1"
                     /translation="MAQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTEGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(10483..11574)
                     /locus_tag="TVB59_001249"
                     /pseudo
     CDS             complement(10483..11574)
                     /locus_tag="TVB59_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378871.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            complement(11628..12146)
                     /locus_tag="TVB59_001250"
     CDS             complement(11628..12146)
                     /locus_tag="TVB59_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1010145.1"
                     /translation="MTNNIAKLIEESGKKIKSISEALDISYPTLSSYNQGIRKPKKEN
                     AQKLADYFGVSVAYILGIDEEKYAPSNLKIVTDSFKTSEITSVTPFKSDMEKLKKGIE
                     LGEIHLSMPLNEVFSDDFRRILSNYLMDYEETFIKDLIKFMNNQGQKSDIWKTWIQTE
                     EFQIRRADRDRK"
     gene            12299..12583
                     /locus_tag="TVB59_001251"
     CDS             12299..12583
                     /locus_tag="TVB59_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1010146.1"
                     /translation="MSEEATLVVQLPKVLEKQLRAHYDEMVSTAIERALEDKELYKPM
                     VRMAALSRWLDVSTTTLQKWTREGMPTMVIDGVTLYDKRAVTRWLKQYER"
     gene            12592..13077
                     /locus_tag="TVB59_001252"
                     /pseudo
     CDS             12592..13077
                     /locus_tag="TVB59_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643974.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication protein DnaD"
     gene            13129..13416
                     /locus_tag="TVB59_001253"
     CDS             13129..13416
                     /locus_tag="TVB59_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HEL1010147.1"
                     /translation="METLWHRELTQQEKVLLEGFAVNDSLLQLAIQKTEELEPKKQNM
                     SYVKGILMNWEARGFITVDQVIASEEDYRPLEIANVEVSEDFLAAMDIWKD"
     gene            13431..13721
                     /locus_tag="TVB59_001254"
     CDS             13431..13721
                     /locus_tag="TVB59_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010148.1"
                     /translation="MTVYYQLENMLVAGFKSQDEYDRYQALKRDYEGESEDYSFSIRE
                     ITNQLEIICQTSENDFPNLSEALMIDYLELVGELKRYDTNQADRYLGMVRHV"
     gene            13714..14076
                     /locus_tag="TVB59_001255"
     CDS             13714..14076
                     /locus_tag="TVB59_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL1010149.1"
                     /translation="MSERIRTILKKFYVTELQNEVLNQLVNDTGLQTFSNYARRMLFK
                     ETSLFMRFDESQFDELIYSLRRIQNNLRQLSKIAEQSQDSQAYRAMDYSRRLVSHYEK
                     QLTRYHKKKKRKLLSKGA"
     gene            14076..14432
                     /locus_tag="TVB59_001256"
     CDS             14076..14432
                     /locus_tag="TVB59_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL1010150.1"
                     /translation="MDKRRIRNVIKQVFLSEEENQKLLEKMKQDGFTNFSLFARKQLL
                     KPDFETWLVSFPEYQPLTGRLLSVGRTINGIAKSATQFGKISQHDLMELGQLMEELVE
                     LVEKQVKEDKQRIAKK"
     gene            14776..16320
                     /locus_tag="TVB59_001257"
     CDS             14776..16320
                     /locus_tag="TVB59_001257"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HEL1010151.1"
                     /translation="MSEQAQRQELHRKIWAIADDVRGAVDGWDFKQYILGILFYRFIS
                     ENFKTYIEGGEDFNYEEIPDEVITPEVKDDAIKTKGYFIMPAQLFSNVVKTARSNDNL
                     NTELKDIFDAIEASAMGYASENDIKGLFDDVDTRSNKLGSTVPERNERLALILEGIAS
                     LDFGSFEDNHIDLFGDAYEFLISNYASNAGKSGGEFFTPQSVSRLLARIVMLGKDEKN
                     KINKIYDPACGSGSLLLQAKKQFTEHIIEDGFYGQEINMTTYNLARMNMFLHNINYDK
                     FSIERGNTLLDPKHGNDKPFDAIVSNPPYSIKWVGSDDPTLINDDRFAPAGILAPKSK
                     ADFAFIMHSLSYLSNKGRAAIVTFPGIFYRGGAEQKIRQYLVDGNFVETVIQLPDNLL
                     FGTSIATCILILAKNKPTTDVLFIDASQQFKKETNNNVLTEENIEKILKSVEHKNNEE
                     YFAQLISQEKIVEADYNLSVSTYVEKEDTREKINIDVLNKEIAETVKNIDRLRAEIDK
                     IVEELS"
     gene            16322..17584
                     /locus_tag="TVB59_001258"
     CDS             16322..17584
                     /locus_tag="TVB59_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002892408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEL1010152.1"
                     /translation="MTYIDEMIKELCPDGVEWKELGEVVDYEQPTKYIVKSKEYSDDY
                     SIPVLTAGQTFILGYTNEVTGIYPASKEHPVIIFDDFTTARKWVDFEFKVKSSAMKLL
                     SIKSDRQDDVSIRYVWHYLGTIKYTPEQHARQWIGTFSKFKIPLPPLEIQGEIVKILD
                     KFTEHVTELTAELTAELTFRQKQYSYFRDKLLSFDDESMGGANDKVYTVQWKTLGEVV
                     NFRRGSFPQPYTDMSFYGGEDAQPFVQVVDVADEGFRLNTKTKKTISQKAIPKSVFVP
                     KGTVIVTLQGTLGRVAVTQYDAYVDRTLAIFDGYKQEVDKRYFAHQLKFIFDREKEFA
                     RGSTLKTITKQEFSNFKIPVPPLDIQRRIVQVLDNFDTVCNDLNIGLPKEIELHQKQY
                     AYFRDKLLTFTAEGVYTDSTVQYSTDKT"
     gene            17593..18198
                     /locus_tag="TVB59_001259"
     CDS             17593..18198
                     /locus_tag="TVB59_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEL1010153.1"
                     /translation="MTWVFGPIKVELGAVCDVVRGNGLQKKDFVNEGYPVIHYGQIYT
                     FYGLSARVTKSFVSPEVGQKLKKAKTGDVIVATTSENIEDVGKALVWEGAEDVCIGGH
                     SCVLHTEQNSKYLLYYFQTTVFQKQKEKLVIGTKVIELYPKNLEKAIIILPPVYEQGR
                     IVSILDKFDTLTSDLTQGLPKEIEQRQKQYEYWRDLLLNFP"
     gene            18213..19421
                     /locus_tag="TVB59_001260"
     CDS             18213..19421
                     /locus_tag="TVB59_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEL1010154.1"
                     /translation="MGNDIKFENLEQISDNIISSNKKVHLLYAYNATGKTRLSMELKN
                     KVNETDSDGNSIKHILYFNSYTEDLFTWDNDLENDEDRYLIYDKRTYFGNFLEEQQLF
                     ERAVDNFQKYVGRSIDIEFQDVIETVKDEFGNVQKDNRGEALTISNKKSIRFKVDGHT
                     IKVSRGEERIFVWSVFLTLLEIIIEDLTESADTSEFSKMNYIYIDDPISSLDDTNIIN
                     AAIYLSDVIGSAENTDLKFVVSTHQALFYNVLYNEIRFDRRIKKKVFYVMKATDEIED
                     EKQFKYLLTDVEGDSPFGYHLRVREELRKAIQDEQVEKFHFALFRNLVEKTATFLGYG
                     RWENILLGLDVAGHVITSENIKLYTQLIDLYTHNRHADLEYRELPPQEKNTLINLFNS
                     FDSIYRFKED"
     gene            19424..22519
                     /locus_tag="TVB59_001261"
     CDS             19424..22519
                     /locus_tag="TVB59_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019771596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HEL1010155.1"
                     /translation="MTEIIQTDTILEAKNFIVLEKYTKLEKPSTYQTEADLERELVSD
                     LRQQGYEYLNNLTTPEALLDNLKTQMEALNGVVFSEAEWLRFLEEYLNKPSDGLIDRT
                     RKLHDNHIYDFIFDDGHIQNIYLWDKKNISRNKLQVINQMSQVGTSSNRYDVTILVNG
                     LPLVQIELKKRGVAIREAFNQVHRYSKESFNEENSLFKYLQIFVISNGTDTRYFANTT
                     KREKNSFDFTMNWALKNNEPIKDLKDFTATFFSQQTLLNILINYSVFDTSDTLLIMRP
                     YQIAATERIIWKIRSAIDSKIKSGPETGGYIWHTTGSGKTLTSFKAARLATEMDKVDK
                     VFFVVDRKDLDYQTMKEYQRFSPDSVNGSNSTAGLKRNIEKDDNKIVVTTIQKLNNFM
                     SSEAQHEIYNKQVVFIFDECHCSQFGEAQKRLKQKFKKYCQFGFTGTPIKVENALGSE
                     TTASVFGRELHAYVITDAIRDQKVLKFKVDYNDVRPQFKSLETEQDLGKLSAAENKKA
                     LLHPTRITEISAYILEHFNQKTHRQNGKGFNAMFAVSSVEAAKAYYQELQDQQAGKAK
                     PLKIATIFSYAANEEQAAIGEIDDETFSPADLSDISSKEFLSGAISDYNRLFQTNFSI
                     NGNEFQNYYRDLAKRVKSGEVDLLIVVGMFLTGFDAPTLNTLFVDKNLRYHGLIQAFS
                     RTNRIYNATKTFGNIVTFRDLEKATTDAIKLFGKTETADILLERSYEDYMNGYIEAGQ
                     EQKGYLEVVKELQERFPDPTTIIKESDKKEFVTLFGQFLRLDNILQNYDDFMSLQALQ
                     ELDVTDIEALADFKGRFHLDDEAVAVLSQLDIPSVREIQDYRSAYNDIKSWYDNERRN
                     QQNNDSEIDWDAVVFEVELLKSQEINLDYILELIFETNQKVSDKDQLIEEITRTIRAS
                     LGQRAKESLIVDFINASDLDSFSEKSDILEQFYTFARQKQKEAVANLIETEGLNVESA
                     SRYIQMSLKREYASENGNALNEALPKMSPLNPQYRTKKQMVFEKIVDLVEIFKGIGGE
                     I"
     gene            22687..24138
                     /locus_tag="TVB59_001262"
     CDS             22687..24138
                     /locus_tag="TVB59_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014293901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA binding domain-containing protein"
                     /protein_id="HEL1010156.1"
                     /translation="MENKKDLIQTLAYYQFSLENQYLDRKSARKKPQELLKHLIAFAN
                     ADGGQLVIGIEDEKQDNIITGFKDGRAYPIDDFKKIDHEMRETPLDLSLEEIPVLNHK
                     GEDDLILVISVELSSNRVIAAPNDEVYLRQGDESVKLSYEQRTQLSYDKGQRFFEDEV
                     VPDATLEDIDDGLVQDFKNRFDISERSMEEVLKARRFLVNGKLTKAAILLFAKYPSAF
                     FPQARVRFQRFDGTDMGTGSSFNVIKEVTFDDALPTLIIKVRDFIRTQLREFQYLDDN
                     GQFQILPEYPEFAWFEGVVNAVTHRDYSVYGDHIRVLMFDDRLEIHSPGKLPNIVTVD
                     NIKHECFSRNPRIARTLTEFGWVREMNEGVKRIYSEMESAFLHEPKYLEPGNKVVLTL
                     ENNIVSRHLRTRDSLEKQFSDFGNLTADEQAIVHYMYNSGDKMTTAKAIELTGRSRSF
                     VVKMLHHLRDLEIITWFGSSKNDRNQYYLLVDK"
     gene            24500..24787
                     /locus_tag="TVB59_001263"
     CDS             24500..24787
                     /locus_tag="TVB59_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEL1010157.1"
                     /translation="MATLIRDRQYNFRVNTEMMEEAKRILEAKNISVPDALNLFVERV
                     VEEKDLPIKTAEQIRAESFLNELISELDEGYQDILAGRTKPANEVFSKYGL"
     gene            24777..>25038
                     /locus_tag="TVB59_001264"
     CDS             24777..>25038
                     /locus_tag="TVB59_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEL1010158.1"
                     /translation="MAYDIYISNKAEQDLDEIYNYYLTEFSHSSAQKVIESLQSAISI
                     LEISPEGYVDFDDRVGRKLFPEGQLRMIPSKHFIVFYLIRQSR"
BASE COUNT         7690 a         4370 c         5633 g         7345 t
ORIGIN      
        1 gcaggtcttt ttttgctgcg tcatcagcgg cttagcgtgc ttggctgtag ggctatagtg
       61 ataaaagaga gtgctgctgg tattgacagc cctttcaaac tttttctagg aatgcctttt
      121 agggtcgtga atttttaact attttatggt aaaatgtagc agatacgtcg tttgatacaa
      181 agaggagtgt gtaattcctt acagattgct ctttgtagca aaacaacgta tagccataaa
      241 aaataaaagg ctagcaagct ttggtcgggt caaacggcta tggtaggcta gctcgttcaa
      301 ggagaaagaa tgtcaaaaca aacatttaca acaacctttg caggcaaacc acttgttgtt
      361 gaggtcggtc aagtagccaa gcgagcaaat ggtgccactg tcgttcgtta tggggagtct
      421 acagtgctaa ctgctgctgt catgtctaag aagatgtcaa caggagactt tttcccgctt
      481 caagtcaatt atgaagaaaa aatgtatgcc gcaggtaaat ttcccggtgg ctggatgaag
      541 cgtgagggac gtccgtcaac agatgcgacc ttaaccgctc gcttgattga ccgccctatc
      601 cgtcctatgt ttgctgaggg ctttcgtaat gaggtccagg tgattaatac tgtcctgtct
      661 tatgacgaag atgctagtgc ccctatggct gctatgcttg gtagctcatt agccctatcg
      721 atttcagata ttccttttaa tgggccgatt gctggtgttc aggtggccta tgttgagggt
      781 gaatttatca tcaatcctga taaggcccag caggaggctt cattattaga gttaaccgta
      841 gcaggaacaa aagatgcgat caatatggtt gaatctggtg ctaaggaatt gccagaggct
      901 attatgctag aagcactttt ggttggccat aaggctatac aggagttgat tgcttttcaa
      961 gaagagattg ttgcagcggt gggcaaggaa aaggctgagg tagagctatt acaggttgct
     1021 gctgatttgc aggctgagat catagagact tacaatgctg atttgcagca ggctattcag
     1081 gttgaggaga aaaaagcacg tgaagccgca accgaggctg tcaaggagcg tgtcatagct
     1141 gcatacgagg agcgttatgc agcagacgaa gagcatgacc gtatcatgcg tgatgtggct
     1201 gaaattttgg agcaaatgga gcatgctgag gttcgtcgcc tcatcactga ggataaggtt
     1261 cgtcctgatg gtcgtcgtgt tgatgagatt cgtccgcttg ctgctgagat tgatttctta
     1321 ccaagggtgc atggctcagg cctctttacg cgcggtcaaa ctcaagcttt gtctgtcttg
     1381 actctagccc caatgggaga tactcaaatt attgatgggc ttgagcctga gtacaaaaaa
     1441 cgcttcttgc accactataa tttccctcaa tattctgttg gtgagacagg ccgctacggt
     1501 gcagcagggc gtcgtgaaat tgggcatggt gctttaggcg agcgcgctct tgcacaagtc
     1561 cttccaagcc ttgaggcatt tccatatgct attcgtctag tggctgaggt attggaatca
     1621 aacggttctt cctcgcaggc ctctatctgt gcagggacgc ttgctttgat ggctggtggt
     1681 gtgccgatca aggcaccggt tgcgggtatt gctatgggac ttatctctga tgggaccaat
     1741 tatactgttt taacagacat tcaggggtta gaggatcatt ttggcgacat ggacttcaag
     1801 gttgctggga cacgccaagg gattacagca ctgcaaatgg atatcaagat cgaaggtatc
     1861 acccctcaaa tcctagaaga agccttggcg caggctaaaa aggctcgctt tgaaattctt
     1921 gacttgattg aggcaaccat tgctgagcct cgtccagaat tggcaccaac agcaccaaag
     1981 attgatacca tcaagattga tgttgataag attaaggtgg ttattggtaa gggtggcgaa
     2041 accattgata agattattgc tgagacaggt gttaagattg acattgatga ggaaggaaat
     2101 gtttcaatct actcaagtga tcaggacgct atcaatcgtg ctaaggaaat cattgctagc
     2161 ctagtacgtg aggctaaggt aggagaggtc taccatgcta aggttgtccg tattgaaaaa
     2221 tttggtgcct ttgttaacct ctttgacaag acagatgcgc tggtgcatat ctctgaaatt
     2281 gcttggagcc gcactaccaa tgtctcagat gttcttgaaa tcggtgaaga ggttgacgtt
     2341 aaggttatta aggttgatga taagggacgt attgacgcat caatgaaagc cttggtgcca
     2401 cgcccgccaa agccagaaaa atcagaagca aaaaaagaag gcaaacatga ctaatacaaa
     2461 tgaactagat attcgtttaa gagcctttat caatgcccct gataattttt tagatagcgt
     2521 ggccttggtt aatgcttttc accagtatcc ggtgtgggca gcaaaaaagc cctatgctat
     2581 tgagattgaa ggggtaagga tttttcctgt attcacagat aaggacgaca tggcgacctt
     2641 taaagaggag caaaagagtg cacaagctca gtattgggta gagcgctctg ctcttactgt
     2701 cttggaggag gctgttcatg caggtgctgc tgggctaggc tttaatctca agaaaaaggg
     2761 agattttggc aattctacag tgttcaagtc tgctgatatg attcagttta tgaacaatta
     2821 cacaacgatt ttgaatacct tgatgagtga tgacaatagc gcagcagata ccctggatag
     2881 gctttatctg gtgccggcct ttgtttaccc taaggaagag gagcattact atgacaggct
     2941 ttttccaacc atgtcaactc cagaggggaa gcgttatgtt cctgcctttt caaatcttca
     3001 gagcttcgct aaatggtaca atcaagagga gtttggcggc ctttttagga aatcaggtgg
     3061 tgttatctta acatggaaga tagcagacat ttatcagcca agaaatggca ataatgacat
     3121 agacgagacc tttggggttg ctattgaccc ctttgatgat cagcagattc ttgttgattg
     3181 gtctgatatt gacacataaa aggagtttaa atgggctggt ggaaggacaa tattgatatt
     3241 gtaaagcaac tagatcctgc tgcacgtagc accctagagg ttatcctaac ctaccctgga
     3301 ttaaaggcct tggcagcgca caggctgtca cattttttgt ggcagcatgg ctttaagctg
     3361 ctggctcgaa tgcatagcca gttttggcga ttttggacac agattgaaat ccacccagga
     3421 gctaggattg cttcaggtgt tttcattgac catggggctg gcttggtgat tggtgagacg
     3481 gccattgttg aaaaaggagc catgctttat catggagtga cgcttggtgg aactggaaaa
     3541 gatcgaggga agcggcaccc tactgttcgt gagggggcac tgatttctgc ccatgctcaa
     3601 attatcggtc ctgtcgagat tgggaaatcg gctaaggttg gagctgcagc tgttgtgttg
     3661 actgatgtac ctgctggcgt gacggtcgtt ggcattccag cccaaattgt tcgagtgcat
     3721 gagaaaaagc cctcaaggca ggattaatag ttttctctag aggcagtcag ccaaaaaacg
     3781 ggagagttag agccctatgc ttacctcagt tgctgacagc ttgcgcagtc taggagaaaa
     3841 ggataaaaac aaaagggaaa agtgatgata aaaatctatg ataccatgac cagaagtctg
     3901 cgagagtttg taccaataac tgataaggtg gtcaatatgt atgtctgcgg gccaacggtt
     3961 tacaattata ttcacattgg caatgcacgt tcggctgtgg cctttgatac gattcgtcgc
     4021 tactttgaat acgcaggcta tacagtcaat tacatttcaa attttacaga tgtagacgat
     4081 aagattatca aggcagccaa ggaatcaggt gtatcaccca aggaattggc ggacagattt
     4141 attgctgcct ttatggagga taccaaggca ctcggtgtga agccggccac caaaaatcca
     4201 cgcgtcatgg actatatgga cgagatcatt gcctttatcg ctgctttaat caaaaaaggc
     4261 tatgcctatg agtcggcagg tgatatttat ttccgcgtgg caaaggcatc aaattatgcc
     4321 agactggcta ataaaacgat tgctgatttg gaggctggtg ctagtggtcg tacagatacc
     4381 gaaactgctc tcaaggaaga tcctttggac tttgccctat ggaaatcagc aaagctaggc
     4441 gagatttctt gggcaagtcc ttggagcgcc ggtcgtcctg gctggcatat cgagtgctct
     4501 gtaatggcaa ccgagctttt gggagatacc attgatattc atggtggtgg cgcagacctg
     4561 gaattcccac accataccaa tgaaattgct caatcagaag caaaaactag caaaactttt
     4621 gccaattact ggatgcataa tggctttgtt aatgttgaca acgaaaaaat gtctaagtca
     4681 ctgggcaact ttgtgactgt tcatgatctg ctaaagacgg tggatgggca aacgctacgc
     4741 tttttcttgg ctactcagca ttatcgtaag ccgattaatt ttactgaaaa agctattcat
     4801 gatgctggag ttaacctcaa atacttgaaa aacacgcttc agcagcccac agtagccact
     4861 gcagatgcta gccagcttgc tgcctttatc actgccttca aagcagccat gaatgatgat
     4921 tttaatacag caaatgggat tacagtctta tttgacatgg caaaatggat taactccggc
     4981 gcctattctg aggctgtcaa atcagcattt gaagagatgc tagctgtttt tggcattgtc
     5041 tttgaagcag aaagcctaga cacagagatt gagcagctga ttgctgagcg tcaggaggca
     5101 cgtgccaatc gagattttgc aagggcagat gctattcggg atcagttggc agctcagggg
     5161 atcaagctgt tggatacaaa agaaggtgtg aggtggatac gtggctaatt cagttgatgt
     5221 caatttgatt aatggcattg cccttgcctt tgttggtgat gctgtttatt cttactatat
     5281 tcgtcgtcat ctgattttcc aaggccagac caagccaaat aagctccact accttgcaac
     5341 aaaatatgtt tctgcaaagg cacaggcttc tctgattcag gccatgctag aagcacaact
     5401 attgaccgaa aaagaaaaag acatctacaa acgaggccgc aataccaaca gccataccaa
     5461 ggctaaaaat gctgatgtag taacctatcg tatgtcaaca ggctttgaag ctattatggg
     5521 ctaccttgat atgacaggtc agacagaacg gctagaactg ttgatccagt ggtgtatcaa
     5581 gcaggtggag aacagtcctc aatcataatg atgaatcatc taaaacattc tctgtgtcac
     5641 tagcgatctg ccatcgctca aagtcatgag agtgttttta tgttgtgttt aaaagttatg
     5701 tcacaatata gatacacacg aaacataaaa taaatatttg taacaaaaac gtaacaaaac
     5761 tattgaaaaa ttttccgaat agtttataat gaaagagtca taataaaatg ataggagaat
     5821 gtctatgaaa ccaatgagaa acgtagcctt agttatttca gcaatgttac tgttaagctc
     5881 acaggccttt gtatcagcag tagcagcaca ggacaatcaa ccaaccatag cagttcaagc
     5941 acaggcagca gctgaggcca atgtcagtgc tcgtatgcgt tcagatcagc ccgttattga
     6001 agctaacatt gctaccagtc agccagttag ccaaagcact gaggctacta ttttactaaa
     6061 ggatgccaaa ggcaacgcga ttaatagcac agcctatacc atgcaggctg gtcaaagccg
     6121 gttttcagta tggtttgacc ttacgaacct aaaggttagt gattatagta tatcagtgag
     6181 tgttcctgat aaagaaaagg cctttagtgg tagctcagca cctattcatt ttgatggaaa
     6241 gccaaccaaa aataccccag agacagaaca gaaaaacagc aatccagtac cagctaataa
     6301 ccagcctaaa cccgctgcta gcggcagggt gacaagcact gagcaacccc aaaatgtgcc
     6361 tagcgcgact gctagcgcca atcatatgac aagaaccaat catcgatctg ataaggtcct
     6421 aaaggcaagc tcaagcaaca caccatcagc tgccaaatca atagactctg ctgagaaagg
     6481 caagggcatg ctttctgata gcacagccca agataaagag caaaaaggct ttccttggct
     6541 gctatcatct ctaattgcaa ttacagcagc tgctttactt gctcttgtca tcaaagctgt
     6601 tcacaggaaa taaaaagagc agcaagagct attttattgc tttcgtggta taataaaaac
     6661 catgaaagct aaagaaatca atgaaaccaa ggatattgtt tatggcgtcc atgccgttac
     6721 cgaaagccta ctagccaata ctggaaataa gctttacatt caagaggatc tgtgtggtaa
     6781 gcatgttgat cacatcaagg atttagccac tagtaagaag gtgtctatct cttggacaaa
     6841 aaagaaagct ttgaccgaaa tgacagcagg agctgttcat cagggctttg cgcttcgagt
     6901 gtcagccttt gcttatactg agctagatga gctgctagag ctggcacagc aggaggataa
     6961 tcccttgctg ctcatcctag atgggctgac agatcctcat aattttgggt ctattttaag
     7021 aacagccgac gcaacaggtg tttgtggtgt gattatccct aagcatcgtg ctgttggtgt
     7081 gacaccagtg gttgctaaga cctcaacagg agctgttgag catgttccaa ttgctcgcgt
     7141 gacaaatctt agccaagcat tggatcagct aaaagcaaat ggcttttggg tcttcgggac
     7201 agatgtaact ggtacaccat catacaagtg gaatacctca ggcaagctgg ctttgattat
     7261 tggcaatgag ggtaagggca tttcagctaa catcaaaaaa caggtagatg aaatgattac
     7321 cattcctatg atgggtcatg ttcagagctt aaatgctagc gttgcagctg ctattttgat
     7381 gtatgaagta tttagaaata aattatagat gaaaaaaaga ctattgctgg ttgatggcta
     7441 taacatgatt gccttttggg aatcaactcg tcagtttttt aagacaaacc aattggatca
     7501 agctagaagg atcttgctaa ataagctgaa caactatgcg cattttgatg atagtgacat
     7561 tatttgcgta tttgatgctc agtatgttcc aggacttaga cagcgttatg accaatatag
     7621 gatttctgtt atttttaccg aagaggaaga aacagctgat agctatattg agcggactgc
     7681 tgctgagcta aacaccgctc taaccatggt agaggtggct actagtgatc tgaatgaaca
     7741 gtggacgatc ttttcccaag gcgccttgcg tgtcactgct aaagagcttg agcagcgtgt
     7801 taatgctgtt aagtcggatt tagataagct gtcacaggat attgatctta aaaagcctag
     7861 actgggtccc tttgatcaag ggcagcttaa tcagctcaag gactttatga atcgattaga
     7921 tgattaataa gcttatcttg ctagcttttc taggtatgat tctccaggct gctagagcag
     7981 ctcatacgat ctaacggtga tcatttctga ggcagctggt tcttattgct ttcttagctg
     8041 atattttttt gttatactat gagaaaatca tttgattatt aaacgataat gacgttactt
     8101 gggagttcag atgacatttg tattgatgac agattcaaca gcggatttag attctttttg
     8161 ggcaaaggag cataacatcg atatagtagg cctaactgtt gaatgtgatg gcaaggttta
     8221 caagacggtt ggtccagata gattaacgag tgatgctttg ctagctatga tgaaaagtgg
     8281 gagccagccc aaaacaagcc agataaatgt tggtcagttt gaagagattt ttcgacatta
     8341 cgcagctgat aaccaagctc ttttatatat cgccttttct tcagtcctat caggtaccta
     8401 tcaaagtgct gtcatggcac gtgagctggt tttggaggac tatccggacg ctgtaattga
     8461 gattgttgat agcttggctg cagcaggagg agagggctat ttgaccatgc tagcctcgga
     8521 ggcgcgtgat aatggaaaaa gcctattaga aaccaaagcg ataatagaag gtattttgcc
     8581 tcgcttacgc acctatttct tagtagatga tctttttcat cttgtgcgag gaggacgctt
     8641 gtcaaaaggc tctgctttta taggcagcct agtgaatatt aagcctctct tatggattga
     8701 tgccagcgga aaattagttc ctattgccaa gattcgtggc cgtaaaaagg ccattaagga
     8761 aattgctgac agagccacaa aagatattgc tgattcaact gttgttgtgt cctatactag
     8821 tgatcagact ggggcagatg acctacgaga acagctatta gcacatgaag gtatcagtga
     8881 tgtctttatg ctgccgctcg gaccggtgat tgctgctcat acaggtccag ataccttagc
     8941 ggtctttgtc atcggcaagg aaaaaagata aaaagaaaag gattgaagcg cttgtttcaa
     9001 ttcttttttg tcgactatag cttgttttag ctgtgatgcc gcttaagagt atgggtgttc
     9061 gcatttttta tttttaatca aaagttagaa tgaattgttt gacaatgaag gtgcgcgtgc
     9121 aggtaaggaa ctagcataac agaacagggc tttttgattt gccagaagtc agatgtcaaa
     9181 tgttttagca gttgacagga gctttggtca ttccaccact aatctttgta ttgttatttg
     9241 cataggagct aacaggaact gagcggattt tttggaggga agtcaaggct aatagtccag
     9301 ctcaaaagca agcctgttct tcttgtgaaa aagcaaaaat aatcaaagaa atagagctaa
     9361 accacttgac tatcagttaa gaagtttgat actatagtag acggtattgt ttaccccatt
     9421 tgaaaggccc cggaaccttc caaatacctt cgatggaccg gaacatccat cactaatgta
     9481 aacaaaaacg aattcgtata ggagaaatca tgaacaaaac aactttcatg gctaaaccag
     9541 gccaagttga acgcaaatgg tacgttgttg acgcaacaga tgtgccactt ggacgccttt
     9601 ctgcagtagt tgctagcgta cttcgcggaa agaacaagcc aactttcaca ccgcacactg
     9661 atacaggtga ctttgttatt gttatcaatg ctgagaaggt taaattaact ggtaaaaaag
     9721 caactgataa ggtttattac actcactcaa tgtacccagg tggcttgaaa tcaatcactg
     9781 ctggtgagct tcgctctaaa aatgccgttc gtttgattga aaagtcagta aaaggcatgc
     9841 ttccacacaa cactcttgga cgtgcacaag gtatgaaatt aaaggtcttt gttggcggtg
     9901 agcacactca tgctgcacaa caaccagaag tacttgatat ttcaggactt atctaagaga
     9961 aaggagcatt aaataatggc acaagcacaa tatgcaggta ctggtcgtcg taaaaacgct
    10021 gttgcacgcg ttcgtttagt tccaggtact ggtaaaatca ctgttaataa aaaagatgtt
    10081 gaagaataca tcccacatgc tgacctacgt ttagtcatta atcagccttt tgcagtgact
    10141 tcaactgaag gctcatacga cgtttttgtt aacgttgtag gtggtggtta tgctggtcaa
    10201 tcaggtgcga ttcgtcatgg tatcgctcgt gcgcttcttc aagtggaccc agatttccgt
    10261 gactcactaa agcgcgctgg tcttcttaca cgtgacgcac gtatggttga acgtaaaaaa
    10321 ccaggtctta aaaaagcccg taaagctagc cagttctcaa aacgttaata tccagttata
    10381 ccaacgtttc agagcacttt gcgaagtttt cgcaaggtgc ttttttgttg aaaaaagcac
    10441 cttggtaatc tgttgagacc tagttttaag agaggttaag ttagaatgac tataagtatc
    10501 taaagtcatc tggctgctag catgacctag acgcttagcg gtattaactg ggtcaattcc
    10561 catttcaatc atcaaggttg cgtgagtgtg cctaaaccca tgtgggctaa tctttttaag
    10621 attatgcttt cgtataatgc gttttagaat attgttgata tagtcagcgt gtaagggttc
    10681 tatctcacca tctctgttgc agtatgtaaa cataaattct ttgtcgagag aaaggggctg
    10741 tactgataat tgcccctttt ctttgctagt ttcctgtttc catttgttga ggatagaaca
    10801 ggtttcatca tcaagataga tagagcgtac tgagaatgta tttttagttc ctttttcaat
    10861 ggcatgacca tctattcttc ctaaactttt gctgactgtt aatagttgat tctcagaatc
    10921 aaaatcttcc catttgaggg cgtagagctc tccttttcgt aacccgctgt atgctagtaa
    10981 tcgaaataga gcataatgtt tataaggttc attttctaaa atgattgtca aaaaatgatg
    11041 caactcgtta actgtccagt agttctcact gacagttttt ttgagtttag gcataataac
    11101 tttgctcata ggattacgtt caatatgatt catattgatg gcaaattcaa aggttttaga
    11161 ggtgtatgac ttgatttgct tcatgttctt gaatgatttc gctttatctg tgataaaggt
    11221 ttggcagtct agcggactga tttttgaaat ctttttctct ccaaaggttg gaagaatatg
    11281 aaggcgatat aaatcggccg ttttagctgc agtagttgtt tcaacggtat ctttgtaagc
    11341 ttcataccac ctttgatata gttcttggta agtataggtt gtttgagcag taagatgggc
    11401 aaaagttcca ctattcagct gatgattaac agcagtttca tgagctttgg cagctttacg
    11461 cgtcttgaat cctcgtttag tgtaatattt tttcttaccg tagtcgttta gaccaaggta
    11521 aactttaaca aaataggtaa ttccttttgt agattggtat ttgtgtacag acataacagt
    11581 tctccgtttc taagttttcg gagcttatgt aattgagaaa tattagtcta ttttctgtca
    11641 cgatctgctc gtctaatttg aaactcttcg gtttgtatcc atgttttcca aatatccgat
    11701 ttttggcctt ggttattcat aaacttaatt aagtctttga taaaggtttc ttcataatcc
    11761 attaagtagt tagaaagaat acgtctaaag tcatctgaga aaacctcgtt taagggcata
    11821 gacaaatgaa tctctcctag ttcgattcct ttcttaagct tctccatatc gcttttaaaa
    11881 ggtgttacag aagtaatttc agatgtcttg aaactatcag tgacgatttt taaatttgac
    11941 ggagcgtact tttcttcgtc aattccaagg atgtatgcca ctgagacacc aaaataatcc
    12001 gctaactttt gagcattctc ttttttaggt tttcgtattc cttggttata gctagatagt
    12061 gttgggtagg atatatctag cgcttcactg atacttttta tttttttgcc actttcttct
    12121 ataagtttag ctatattatt agtcatagat tcctcctaat tgatattcta ccacatttaa
    12181 tacaaaaagt ataataccac ttgacaagaa tacaaaaagt atttataatt taaaatgtat
    12241 aataaaatat acaaatttcg gagtttattt aattgagaaa tggaaacgag gtaatgatat
    12301 gtctgaagaa gcgactttag ttgttcaact tcccaaagtt ttggaaaaac aattaagggc
    12361 acattatgat gaaatggttt ctacagctat tgaaagagcg ctagaggata aagaattata
    12421 taaacctatg gttcggatgg cagccctttc tagatggctt gatgtgtcaa cgacaacact
    12481 tcaaaagtgg acgcgagaag gaatgcctac aatggttatt gatggtgtga ctctgtacga
    12541 taaacgtgcg gttacacgtt ggttgaagca atatgaaaga tgaggtaaag aatggctaat
    12601 agacgaatgt tgagtaaaac ggtggtgcag atacaacgat ttttacgcct accacttgaa
    12661 gcgcaggcgc tttactgtca cttggtagtc aatgcagatg atgatggtat tgttgaagct
    12721 tttcctgtta tgcggatgat taatgctaat gaggacagtt tgaatttatt aactcttaag
    12781 cagtatttac tcttgttaaa caatgaaatg gtttacttta tcaaggattt ctttgagcag
    12841 aataccatca aagcagatcg ttacacaccg agtagtcatc gtcaacttct tatagattat
    12901 ctgaaggata atcagttgtt ggagtgtcta aatctaggac cacgcttgat taattatctt
    12961 caaaatactc ggctccaagt tggagccagt ctggatccag atgggaaccg caatataatt
    13021 aaagataaga taagtaaaga taggataggt aaagataagt taagtcaaga taagatagga
    13081 ttagataatg atccaatctc atcacaactg actgatgaca tctggttaat ggaaacacta
    13141 tggcatcgag aattaaccca acaggagaaa gtattattag aaggattcgc ggttaatgat
    13201 tctttattgc agttagctat tcagaaaaca gaggagcttg agccaaagaa acaaaacatg
    13261 agttatgtca aagggatact aatgaattgg gaagctagag ggtttataac tgttgaccaa
    13321 gtgatagcat ctgaagaaga ctaccgtcca ttagaaattg caaatgtaga agtttcagaa
    13381 gatttcttag cagctatgga tatatggaaa gactagggga ataatgagtt atgacagtat
    13441 attatcaatt agaaaatatg ttagtggctg ggtttaagtc acaagatgag tacgaccgct
    13501 atcaggctct caagagggac tatgaagggg agtcagagga ctatagcttt tcaatcagag
    13561 aaatcacaaa tcaacttgaa atcatttgtc agacctcaga gaatgatttt ccgaacttat
    13621 cagaagcatt aatgattgat tatttagaac tggtaggaga gttgaaacga tatgatacta
    13681 atcaggcaga caggtattta gggatggttc gtcatgtctg aacgtatcag aactatttta
    13741 aagaagtttt atgtgacgga attgcagaat gaagtactta atcaactagt aaatgataca
    13801 ggcttgcaaa cattctctaa ttatgctcgt cggatgcttt ttaaggaaac atcactcttt
    13861 atgcgatttg atgaatctca gtttgatgag ttgatttatt ctttaaggcg tattcaaaat
    13921 aatttaaggc agttatctaa aattgcagag cagtctcaag atagtcaagc ctacagagct
    13981 atggactata gcagaaggtt agtttcacat tatgaaaagc agttaacgcg ttaccacaag
    14041 aaaaagaaac ggaaattatt atctaaggga gcttaatgga taaaaggaga attaggaacg
    14101 taattaaaca agtctttttg tctgaagaag aaaatcaaaa actgttagag aaaatgaagc
    14161 aagatggctt cacaaacttt tctctttttg ctagaaagca attattaaaa cctgattttg
    14221 aaacttggct agttagtttt ccagaatatc agccgctgac tggcaggtta ctatctgttg
    14281 gtagaacaat taatggcatc gctaaaagcg caacacagtt tggaaaaatt tcccaacatg
    14341 atttgatgga attaggtcag ttgatggagg aacttgtaga actggtagag aaacaagtga
    14401 aggaagacaa gcaacgaata gccaagaagt gatagtcgtt cagtcatttt ggtagaatag
    14461 ttttaaataa aacaacaaaa acgctgatgg tagtcagcgt tttttagcat gtaattgtaa
    14521 aaaatccttg tacggacaat gtgcggcacc gtataaagta cgggaaatca ctaaaaatgg
    14581 agttaggtct ttgcgagctc agatagtgta tacacactat cgtaaaaata gaaccatcag
    14641 taaaggtcag actgacactt tttgattgat gcttatattt tattttgggg caaagcccca
    14701 aaccccttga gaaaacgtgt gagaagtagg gaaaaatggt ataatagaaa tattaaagac
    14761 tgtgaggatt tgaagatgtc agaacaagca caaaggcaag agttgcaccg caaaatctgg
    14821 gcaatcgcag atgatgtccg tggtgcggta gatggttggg atttcaaaca atatattttg
    14881 ggaatccttt tttaccgttt tatcagtgaa aatttcaaga cttatatcga gggtggtgag
    14941 gacttcaact atgaggagat tccggatgaa gtaatcacac ctgaggttaa ggatgatgcg
    15001 attaagacaa aggggtactt tattatgcct gcgcagcttt tttccaatgt tgtgaaaaca
    15061 gctcgtagta atgacaactt aaatacggaa ctcaaggata tttttgatgc cattgaggcg
    15121 agtgctatgg gttatgccag tgaaaatgat attaaaggtc tttttgatga cgtagacacc
    15181 agaagtaata agctaggaag taccgtccca gagcgtaatg aacgcttagc ccttatccta
    15241 gaaggtattg ccagccttga ttttggtagt ttcgaggaca atcatatcga cctttttggc
    15301 gatgcctatg agtttctgat ttctaactac gcttctaacg ccgggaaatc aggcggagag
    15361 tttttcacac cgcagagcgt gtcacggctc ctagcacgta tcgtcatgtt aggcaaggat
    15421 gaaaagaaca aaatcaataa gatttatgac cctgcttgtg gttctggttc tctcttgctt
    15481 caagccaaaa aacaatttac ggagcatatt atcgaggatg gtttttatgg tcaggaaatc
    15541 aacatgacca cctacaactt ggctcggatg aatatgttcc ttcataatat caactacgac
    15601 aagtttagca ttgagcgtgg caatacgctg ctggacccta agcatggcaa tgataagccc
    15661 tttgatgcta tcgtgtccaa cccgccttat tcaatcaagt gggttggtag cgatgacccg
    15721 acgctaatta atgatgaccg ttttgcacca gcggggattc tggcacccaa gtctaaagcg
    15781 gattttgctt ttatcatgca tagcctttct tatttgtcca ataaaggcag agcggctatt
    15841 gtgaccttcc ctgggatttt ttatcgtggt ggagcggagc aaaagattcg tcagtatttg
    15901 gtagacggaa actttgtcga aactgttatc caattgccgg ataatctcct ttttgggacg
    15961 tctatcgcta cctgtatcct tattcttgct aagaataagc cgacaacaga tgttctcttc
    16021 attgacgcta gccagcagtt caaaaaagaa accaataaca atgtcttgac agaagagaac
    16081 atcgagaaaa ttctgaaaag tgttgagcat aagaataatg aagagtattt tgctcagctc
    16141 atttcccaag aaaaaattgt ggaagctgac tacaatctct ctgtatctac ctacgtggaa
    16201 aaagaggata cgcgtgagaa gattaatatt gatgtattaa acaaagaaat tgctgagacc
    16261 gtgaaaaata ttgaccgatt gcgggcagag attgataaga ttgtcgagga gttgagctga
    16321 tatgacctac attgatgaga tgattaaaga gctttgtcct gacggagtgg agtggaaaga
    16381 gttgggtgaa gtcgttgact acgaacagcc aacaaagtat atcgtaaaat ctaaggaata
    16441 cagcgatgat tattccattc cagttttgac agcaggtcag acatttattc ttggatacac
    16501 aaatgaagta actggtattt atccagcaag taaggaacat ccagttatta ttttcgatga
    16561 ctttacgaca gctagaaagt gggtggattt tgaatttaaa gttaagtcct cggcgatgaa
    16621 actactctct atcaagtcag accgtcaaga tgatgtttca ataaggtatg tttggcacta
    16681 tttaggaaca ataaaataca caccagaaca gcacgcacga cagtggatag ggactttttc
    16741 taaatttaaa atcccccttc ccccactaga aattcaaggg gagatagtta aaatacttga
    16801 caaattcacg gaacatgtta cagaattgac cgcagaattg accgcagaat tgacctttcg
    16861 acagaaacaa tattcttatt ttagagataa gctcctaagt tttgatgatg aaagtatggg
    16921 aggggcgaac gataaggttt acactgtcca gtggaaaacg ctgggggagg tggtgaattt
    16981 taggagaggg tctttccctc agccttacac agatatgtcg ttctatggtg gagaagatgc
    17041 ccaaccattt gttcaagttg tagatgttgc tgatgaagga tttagactga atactaaaac
    17101 gaaaaaaaca atttctcaaa aagctattcc aaaaagtgtt tttgtaccta agggaaccgt
    17161 tatcgttacc ttgcaaggca ccctaggaag ggtagcggtt acccagtatg atgcttatgt
    17221 cgatagaacg ttagcaattt ttgacggtta taagcaagaa gttgataaac gctatttcgc
    17281 acaccaattg aagtttattt ttgacagaga aaaagaattt gctagaggaa gtactctgaa
    17341 aacaataaca aaacaagaat tctcgaattt caaaatccca gtccctcctc tggatattca
    17401 gcgtcgtatt gtccaagttt tggataattt tgatacggtt tgtaatgacc taaatatcgg
    17461 gctacctaag gagattgagc ttcatcagaa acagtatgcc tattttagag acaaactctt
    17521 gaccttcacc gccgaaggcg tgtatactga cagtacagta cagtacagta cagacaagac
    17581 ctaattaggc tcttgacttg ggtttttgga ccgattaagg ttgagttggg ggctgtctgc
    17641 gatgtggtgc gtgggaatgg tttgcaaaag aaggattttg ttaatgaggg ttatcctgtt
    17701 attcattatg gacaaatcta taccttctat ggattgagtg ctcgcgtgac gaaatctttt
    17761 gtgtcaccag aagttggtca aaaattgaaa aaagctaaaa ctggtgatgt gattgtagct
    17821 actacttctg aaaatattga agatgttggt aaagcacttg tttgggaagg tgctgaagat
    17881 gtttgtattg gtggacactc ttgtgtattg cacacggaac aaaactcgaa gtacttgctt
    17941 tattattttc agacaactgt gtttcaaaag caaaaggaaa agttagtgat aggaactaaa
    18001 gtgattgaac tgtatcctaa aaatttagaa aaggcgatta ttattctccc acctgtatac
    18061 gaacaagggc gtatcgtctc cattcttgac aaatttgata cactaacttc tgaccttacc
    18121 caaggtcttc cgaaagaaat tgagcaacga cagaaacagt atgagtattg gcgggattta
    18181 ctacttaact ttccgtagga ggaagaatag atatgggaaa tgatatcaaa tttgaaaatt
    18241 tagaacagat ttcggataat attatttcta gtaataagaa agttcatttg ctatatgcct
    18301 ataatgctac tgggaaaact aggctttcta tggaattgaa aaataaggta aatgagactg
    18361 atagtgatgg taatagcatt aagcacattt tatatttcaa ttcatatacg gaggatcttt
    18421 ttacgtggga taatgatttg gaaaacgatg aagatcgata tttgatttat gataaacgaa
    18481 cttattttgg aaatttcctt gaagagcaac aacttttcga acgtgctgta gacaattttc
    18541 aaaagtatgt tggtagatct attgatattg agttccaaga tgttattgaa acagttaaag
    18601 atgagttcgg aaatgttcaa aaagataata ggggtgaggc actaacaatt agtaataaaa
    18661 agagtataag atttaaagta gatgggcata caataaaggt gtctagagga gaagagagga
    18721 tttttgtttg gtcagttttc ttaacgctcc ttgaaattat tattgaagat ttgactgagt
    18781 ctgctgatac ctcagaattt tcaaaaatga actatatcta tattgacgat cctatatctt
    18841 ctttggatga tactaatatt attaatgctg caatttattt gagtgatgtt ataggtagtg
    18901 ctgaaaatac tgatttgaaa tttgtcgtct ctactcatca agcattattt tataatgtac
    18961 tttataatga aatccgattt gatagaagaa tcaagaaaaa ggttttttac gtcatgaaag
    19021 ctactgatga aattgaggat gagaaacaat ttaaatattt gttgacagat gttgaagggg
    19081 attctccatt tggatatcat ctcagagtga gagaagaatt gagaaaagca attcaagatg
    19141 aacaggtaga gaaattccat tttgctcttt ttagaaacct agttgaaaaa acagcaacat
    19201 ttttaggata tggacgatgg gaaaatatct tgttaggttt agatgttgct ggacatgtta
    19261 taacatctga aaatattaaa ctctatacac aactgattga tttatacact cataataggc
    19321 atgctgattt agaatataga gaattgcctc cccaagagaa aaatactctt ataaatttat
    19381 ttaatagctt tgattcaatc tatcgattta aagaggacta actatgactg aaatcatcca
    19441 aacagatact attttagagg ctaagaactt cattgtactg gaaaaataca ccaagttgga
    19501 aaagcctagc acctatcaga cggaagcaga cttggagcga gagctggtta gcgatttgcg
    19561 gcagcaggga tacgagtacc tcaacaatct gacgacccca gaagctctct tagataacct
    19621 aaagacccag atggaagccc ttaatggcgt ggttttttct gaggcagaat ggctgcgttt
    19681 tttagaggag tacctcaata agcctagtga tggtttgatt gaccgcaccc gaaagctcca
    19741 cgataaccac atctacgact ttatctttga cgatgggcat atccaaaata tttatctctg
    19801 ggataagaaa aatatcagtc gaaataagct tcaggtcatt aaccaaatgt ctcaagttgg
    19861 gacttcaagt aaccgttatg atgtgaccat tttggttaat gggctaccct tagtacaaat
    19921 tgagcttaaa aagcgtgggg tggctattcg tgaggctttc aaccaggttc accgttacag
    19981 taaggaaagc tttaatgagg aaaattcgct cttcaagtat ctccagattt ttgtcatttc
    20041 aaatgggacg gatactcgct attttgctaa taccactaag cgagagaaaa attcttttga
    20101 ctttaccatg aattgggcac taaaaaataa tgagccaatc aaggatttga aggattttac
    20161 agcgaccttc ttcagtcagc agacactctt aaacattctc atcaactact cagtttttga
    20221 tactagtgat accctcctaa tcatgcgtcc ctatcagatt gctgcgacgg agcgcatcat
    20281 ctggaagatt cgttcggcca ttgatagcaa aatcaagagt ggtcctgaga ctggcggcta
    20341 tatctggcat acgacggggt ctggtaagac cttgaccagt tttaaggctg cgagactggc
    20401 gactgagatg gataaagtgg acaaggtttt ctttgtggtt gataggaaag acttggacta
    20461 ccagactatg aaagaatacc agcgtttttc acctgactca gttaatgggt caaatagcac
    20521 agctggactt aaacgcaata tcgaaaaaga tgacaataag attgttgtga cgacgattca
    20581 aaagctcaat aactttatgt ctagtgaagc acagcatgag atttacaaca agcaagtggt
    20641 ctttatcttt gacgaatgcc actgttcaca gtttggcgag gctcaaaagc gcttaaaaca
    20701 aaagtttaag aagtattgtc agtttggttt tacaggcacg ccgattaaag ttgaaaatgc
    20761 tttaggcagt gagacgacag cttctgtatt cggtcgggag cttcatgcat acgtcattac
    20821 tgatgctatc cgtgaccaaa aggtgttgaa atttaaggtg gattataatg atgttcgtcc
    20881 acagtttaag tcgttagaaa ctgagcaaga tttagggaaa ttatctgctg ctgaaaataa
    20941 aaaagcccta cttcatccaa cacggattac agagatttcg gcttatattt tagaacattt
    21001 taatcaaaag acacataggc aaaacggtaa aggatttaac gctatgtttg ctgtgtcaag
    21061 tgtcgaggcg gccaaggctt actaccaaga gttgcaagac caacaagctg gaaaagctaa
    21121 accattgaag attgcaacca tcttctctta tgcagcaaat gaggagcagg ctgcgattgg
    21181 ggagattgat gacgagactt tcagccctgc tgacttgtca gatattagta gtaaggaatt
    21241 tttgagcgga gcgatttccg attataatcg cctttttcag actaatttta gtatcaatgg
    21301 caatgagttt caaaactatt accgtgattt agctaagcga gttaagtctg gagaagtgga
    21361 tttgctgatt gtcgttggta tgtttttgac tggttttgat gcaccaacct tgaatactct
    21421 ttttgtggat aaaaacttgc gttatcatgg gcttattcag gctttttctc ggacgaatcg
    21481 gatttataat gcgacaaaga catttggaaa tattgtaact ttccgtgatt tggagaaggc
    21541 tacgacggat gctattaagt tgttcgggaa gacggagacg gctgatattc tgttagagcg
    21601 ctcttacgag gactacatga atggctacat tgaggctggt caagagcaaa aaggatattt
    21661 ggaagtcgta aaagaattgc aggagagatt tccagatcca acgactatta tcaaagaaag
    21721 tgataagaaa gaatttgtga ccttgtttgg tcagttcttg cgcttggata atatcttgca
    21781 gaactatgat gatttcatga gtttgcaggc tttgcaagag ttagatgtta cagatataga
    21841 ggctttggca gatttcaaag gacgttttca tttggatgac gaagcagttg cagtactctc
    21901 tcaactggac atcccaagtg ttcgtgagat tcaagattat cgctccgctt acaatgatat
    21961 caagtcttgg tatgacaatg agcggcgtaa tcagcagaat aacgattccg aaatcgactg
    22021 ggatgcggtt gtctttgaag tggagttgtt gaaatcacag gaaatcaatc tggactatat
    22081 tctggaattg atttttgaaa ccaaccaaaa ggtatctgac aaggatcaac tcattgaaga
    22141 aattacacga actatccgtg ctagtctggg tcagagagct aaggaaagtt tgatcgtgga
    22201 ttttatcaat gccagtgact tggacagttt ttctgagaag tcagatatct tggagcaatt
    22261 ttatacattt gcccgtcaaa aacaaaaaga agcagtggct aatttgattg agactgaggg
    22321 attgaatgta gagagtgcta gccgctatat tcagatgtca ctcaaacgag agtatgccag
    22381 tgaaaatggt aatgctctca atgaagcact tcctaagatg agtccgctca atcctcaata
    22441 tcgtaccaaa aagcagatgg tgtttgaaaa aattgtggat ttggtggaga tatttaaggg
    22501 gattggtgga gaaatttaat tattattatt tcttctagat atagaagaga taaactttaa
    22561 attagagctt gaaattttaa gaaatattaa ggcatcatat cagtagtata aaaagctgac
    22621 ttataattta tttggaaacg acagttaatc ctaaaatacg atgcttgata tggaggaggc
    22681 ttaaacttgg aaaataaaaa ggatttaatt caaaccttag cctactacca attctcacta
    22741 gaaaaccaat acttggatag aaaatcagca cgaaagaagc cgcaagaatt actcaagcat
    22801 ctgattgctt ttgccaatgc ggacggcggt cagttggtta ttggtattga agatgagaag
    22861 caggacaata ttatcactgg tttcaaggat ggcagagctt atcccataga cgatttcaaa
    22921 aaaattgacc atgagatgcg ggagactcct ctggatttgt ctttagagga aatccctgtg
    22981 ctaaatcata agggagaaga tgacctgatt ttggttattt ctgttgaatt atcgtcgaac
    23041 cgagtgattg ctgcgcctaa tgatgaggtt tatctgcgtc agggcgatga atcggttaaa
    23101 ttaagctatg agcaacgtac tcagcttagc tatgataagg gccaacgttt ctttgaagat
    23161 gaagtggtac ctgatgcgac cttggaagat attgatgatg ggttagtcca ggacttcaaa
    23221 aatcggtttg atatttcaga gcgctccatg gaagaagttc ttaaagcaag acgattcttg
    23281 gttaatggta aattaactaa ggcagcgatt ctactctttg ccaaatatcc atcagcgttt
    23341 tttccacaag ctcgtgttcg ttttcaacgg tttgacggga cggatatggg aacaggcagt
    23401 agctttaatg ttattaaaga agtaactttt gatgatgctc tgcccacctt aattatcaaa
    23461 gtgcgagatt ttatccgtac tcagctgcgt gaatttcagt acttagacga taatgggcaa
    23521 ttccagattt tgcctgagta tcctgaattt gcttggtttg agggtgttgt caatgcggtg
    23581 actcaccgtg attactctgt ctatggggat cacattcgtg tactcatgtt tgatgataga
    23641 ctggagattc atagcccagg gaaattacca aatatcgtta ccgttgacaa tatcaagcat
    23701 gaatgttttt ctagaaatcc tcggattgcg agaaccctga ctgaatttgg atgggttcgt
    23761 gagatgaatg aaggagtgaa gcgtatctat tctgagatgg aatcagcttt tcttcatgaa
    23821 cctaaatatt tagaaccagg taataaggta gttttgaccc ttgaaaataa catcgtgagt
    23881 cgacatctcc gaacacgaga tagtttggaa aaacaatttt ctgattttgg aaatctgact
    23941 gcagatgaac aagctatcgt tcactacatg tataattctg gcgataaaat gacaacagca
    24001 aaggcgattg agttgacagg gagaagtcgt tcgtttgttg tcaaaatgct acatcatctt
    24061 cgtgatttag aaatcatcac ttggtttggt tcaagtaaaa atgaccgtaa tcaatattat
    24121 cttttagttg ataaatgatt gcagccagga tacttattag taataagaat acagtagaat
    24181 acagaaaaag tggtgttcca taaaatattg atcaccactt ttgattatag aagtttaaat
    24241 aaagtggata tttgtatata gttcacaata tatacctcaa atacaataag aaatagtggt
    24301 tatatttttc tgttattgta gatatttaaa aatagttgat aagtgattac atttagcatc
    24361 tctcaactga taaattccga aaacatactt atttttagta aactaatggc aagtttgcaa
    24421 attgctttat attgctaagt cactattgat ttgttataat cttgttatac ataaggataa
    24481 cgcaattaag gagactataa tggctacatt aataagagat agacagtata attttagagt
    24541 aaatacggaa atgatggaag aagcaaagcg tattttagaa gctaaaaata ttagtgttcc
    24601 agatgctctt aatctatttg ttgaacgggt ggtggaagaa aaagatttac ctattaaaac
    24661 tgcagaacaa attagagctg aatcattttt aaatgaactg atatcagagc ttgatgaagg
    24721 gtatcaagat attttagcag gacgtacgaa gccagctaat gaggtatttt caaaatatgg
    24781 cttatgatat ctatatttca aataaggcag aacaagattt agatgaaatc tataactact
    24841 atttaacaga attttcgcac tcaagcgctc aaaaagttat tgaatctttg cagtcagcta
    24901 tttctattct tgagatatcc cctgaaggtt atgttgattt tgacgatcgt gtaggacgta
    24961 aactatttcc tgaaggccag ctaaggatga ttcctagtaa gcatttcata gtattttatt
    25021 taattcgtca gtcaaggg
//
LOCUS       DARYNN010000031        24179 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.031, whole genome shotgun sequence.
ACCESSION   DARYNN010000031 DARYNN010000000
VERSION     DARYNN010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24179)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24179)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24179
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.031"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(93..869)
                     /locus_tag="TVB59_001265"
                     /pseudo
     CDS             complement(93..869)
                     /locus_tag="TVB59_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779853.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
     gene            complement(965..2512)
                     /locus_tag="TVB59_001266"
     CDS             complement(965..2512)
                     /locus_tag="TVB59_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HEL1010159.1"
                     /translation="MKTSLKKNNKFWTAALAVIVSISCILGLWTVVYAKEKSSDAPTK
                     NEAVQTEVEVNVKYIFEDEKVFKEEKIKAEKGQLLDSGDLPMLPDDMKFIDEFLFYEV
                     KGDGNDEIIRKVAKTEVKDKETQTEEEKPKQDESTQTEATKTEDKGTQTELSKDDISK
                     MEKEAKELQEKFDKLNGELKDKDKQKEKIKDLEDEIDSLKEKMKKDKGNKDLSEDMKK
                     EIDKLTDKVKELEKKATETKKSSEAINSVTPISPISGIKTSSSISPQTPQTSVSSSGK
                     GSSDTVSSGNATKDTSKTEVKEKEKEVRYSNKLTAKAPANNSSQDSSMEGASSNVNTN
                     KGVASSPSKARGTVTENKDNGNKDYPIHHGDSSDNKETDQYSADARQFITFQTKNGKT
                     FHLIINHDEDSENVMLLTEVSEDDLLNMVEKKEAPKQEIVKEEPVKEEVKPEKKEEKS
                     NLGTYIILLLVVGGALGAGYYFKVVKKKEDKELEALEEEDDDFFSEAESEEETNDVDE
                     VEAEDEQ"
     gene            complement(2487..2726)
                     /locus_tag="TVB59_001267"
     CDS             complement(2487..2726)
                     /locus_tag="TVB59_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1010160.1"
                     /translation="MKKELTAVKNRIKKLKDKKALIDEELEPLFIREEELENEEIIMI
                     CRKNNITISDLMTKVNREKAELKKERTNENQFEKE"
     gene            complement(2739..4862)
                     /locus_tag="TVB59_001268"
     CDS             complement(2739..4862)
                     /locus_tag="TVB59_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL1010161.1"
                     /translation="MDGKLKKDFRERHKASLEREMLKAETSSIPEESKLKHNDDYRGK
                     IVHDKDRFQDKVHEKISKVRSENEQIEGTSKRNAKYRASDKGSVNEAGKADYDTEVKN
                     GKIYDSLGQDLDNDGIIDRYDNDFRDSDYFESTYDVEDNLPQKEKSLENPSKNHKAQK
                     NKYKRKNYSESLYTRKKDDVPKENKPEDKKAGKDVAGEKEHSSLSKDQKKKLKKDMVK
                     VSALSGLAKGSETVRDYLSHGSDENKGVEAGEKTADASSKLIHGIKRYSDKKRAKKGY
                     ELTNKDYKIRKRKSKLEFRDAKEELKKTDEYKRASAYKRFQKKNQVKAAISRENKSRL
                     RDRIKEGLIGTLKSSKDMIIRKAKGLMLIFVGIIILGNFVINFAGTGMTGFMNSTNSV
                     LTTSYLSKPNVLSEINQKFSAMESELQSEVDHVEENYPGYDEYILNNTEYIGHNVHEL
                     LSYITSRCGEVKSVSEVETILKELFESMYDLEYREEIEIRYRTVTETYTDEDGNEYTE
                     SHEEPYEYKKLIVTLHKKEMDSIIRRVFKDYPDNLKHYEALFLAQGNMGEAFRNSDLI
                     SANGGVGGGKEYEASSEVQKKIVNAAYITPSPGAGWCAMWVSQVYQNAGLGYIGGNAN
                     DMYRNYTFTSDRSKLKVGMLVAVESSSSGSTAGLTYGHVGIYIGDGKVIDNIGYIRVT
                     TLDDWIATFCKHHPVGFGFPPNVNR"
     gene            complement(4866..7295)
                     /locus_tag="TVB59_001269"
     CDS             complement(4866..7295)
                     /locus_tag="TVB59_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEL1010162.1"
                     /translation="MNKKRKIQQLKLEENKKALKKERKDLKQSKGKSNKEKSGLLDLI
                     FRKEQKRYTVEDTIPYLRLLKSGICQLDEKHFSKSIAFQDINYQLALDEDRDLIFNQF
                     ANFLNSFDPSIAIEFSYINQLGRNEEMKSAIQIPDKGDGFDDIRLEFREMLKSQIVKG
                     NNGLKKSKYVTFTVEADNLEQATSKLERLDIDILSNLKSMGVRAESLTVEERLKILHD
                     ILNPNKTFEFSYKDLKKKESTKTYIVPDEFNFMPSRYFKFGKFIGATSHFQILASELS
                     DRMLSEFLDIDDNINISFHIKAIDQSEAIKMVKRKNTDIDKMRIEENKKAVRSGYDMD
                     ILPSDLITYGEDVKSLLKDLQTRDERMFVVSIVFMNFARTVQKLDNTIAQISSIANKH
                     NCKLKRLDHTQEQGLVSVLPLGVNKIEIDRGLTSSSTAVFMPFTTEELFINSSNSLYY
                     GLNALSHNLIMADRKKLKNPNGLILGTPGSGKSFSAKREMANAILVTDDDVIICDPEG
                     EYGNLVRQFNGEVIKVSSKSKDYLNPLDINMNYGDGDAPLKDKANFIMSMLELVVGGS
                     GLTAEEKSVIDRCLPKIYERYFENPTYDNMPILQDLYDMLKGQEEKVGKKLATEMEIY
                     VSGSLNVFNHRSNVDLNKKLLCFDIKELGSQLKKIGMLVIQDQVWNKVSQNRGNKATR
                     YYIDEFHLLLKDEQTASYSVEIWKRFRKWGGIPTGITQNVKDLLMSKEIENIFDNTDF
                     VLMLNQASGDREILARKLKISLPQLRYVTNSNEGEGLLFFGNTIVPFLDKFPKDTILY
                     QKMTTKPEEVR"
     gene            complement(7207..7596)
                     /locus_tag="TVB59_001270"
     CDS             complement(7207..7596)
                     /locus_tag="TVB59_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HEL1010163.1"
                     /translation="MAYVPIPKDLKKVKTKVAFNLTKRQLIGFTIAGLVGIPVYLFMR
                     KVVPNDIAFIFLIVSTLPIFFITLFEKDGLTFEKYFKHIYLHKFYQPAKRVRKEVYLE
                     QEKKNSATKVRRKQKGIKKGEKGLKAK"
     gene            complement(7600..7863)
                     /locus_tag="TVB59_001271"
     CDS             complement(7600..7863)
                     /locus_tag="TVB59_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1010164.1"
                     /translation="MNKRKTVFTAVVMVAGIMAVIDRIRLHNKAAELEERTQDIGRCH
                     NDFCLMQQRYNKNTDEQLAIIQDEIGSVYEHFEEFSKGKEDGR"
     gene            complement(7883..8749)
                     /locus_tag="TVB59_001272"
                     /pseudo
     CDS             complement(7883..8749)
                     /locus_tag="TVB59_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466911.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(8769..8984)
                     /locus_tag="TVB59_001273"
     CDS             complement(8769..8984)
                     /locus_tag="TVB59_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002838961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family protein"
                     /protein_id="HEL1010165.1"
                     /translation="MEFFAQAVNVLKILVMAVGAGLGAWGVINLMEGYGNDNPGAKSQ
                     GIKQLMAGGGIVLIGLKLIPLLANVLR"
     gene            complement(8988..9299)
                     /locus_tag="TVB59_001274"
     CDS             complement(8988..9299)
                     /locus_tag="TVB59_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL1010166.1"
                     /translation="MKQEMININANLVAEPTFSSFEKEGKEVEVVNFTLVKKYGKGKE
                     YINCAAYGEKADKAKDFEKGDLIHVFGYFKKREKEGKTYKNFVVKSYNKIEKKEENEE
                     E"
     gene            complement(9463..11244)
                     /locus_tag="TVB59_001275"
                     /pseudo
     CDS             complement(9463..11244)
                     /locus_tag="TVB59_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565754.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
     gene            complement(11241..11726)
                     /locus_tag="TVB59_001276"
     CDS             complement(11241..11726)
                     /locus_tag="TVB59_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009346332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HEL1010167.1"
                     /translation="MINEEIARKTLNMEVRAAKVTGKLILNLLKKLMKEAEKLGGLEK
                     LVNANGNEVKLKDMVKKGQLEEIPVEEAELKELKKELNRYGVKFSVMKDKETGKYSVF
                     FQAKDMKVMDKAFKHALAQSEKKTERKESIHKNIEKFKEMAKNSVSKDKIKNKQKEQS
                     L"
     gene            complement(11723..12497)
                     /locus_tag="TVB59_001277"
                     /pseudo
     CDS             complement(11723..12497)
                     /locus_tag="TVB59_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588832.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            complement(12494..13273)
                     /locus_tag="TVB59_001278"
     CDS             complement(12494..13273)
                     /locus_tag="TVB59_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEL1010168.1"
                     /translation="MDFDYFYNREAERFNFLKVPEILVDGEEFKGLSAEAIILYSMLL
                     KRTGMSFKNNWIDKEGRVFIYFTVEEIMKRRNISKPTAIKTLDELDSKKGIGLIERVR
                     LGLGKPNIIYVKDFMSIFQVKEDDLQKLKNFTSEVKDFNLRSKENELQEVKNLDSNYI
                     ENNKSKYSKREYNFSENGLGTFQNVFLAAEDISDLQIIMNSQLDNYIERLSAYIKSTG
                     KTYKDHKATILSWFYKDQGRGKEVKTSNIPTWEEYDKGEHL"
     gene            complement(13360..13641)
                     /locus_tag="TVB59_001279"
     CDS             complement(13360..13641)
                     /locus_tag="TVB59_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010169.1"
                     /translation="MRWIIKIILFPFSLLLSVLTAFLTFILGIGTTILYFLMLMCIVA
                     AIGSFMQKDISLGIEALVLGFLLSPYGIPMVGAAVIAFFKGINEAIKSI"
     gene            complement(13661..15292)
                     /gene="rlmD"
                     /locus_tag="TVB59_001280"
     CDS             complement(13661..15292)
                     /gene="rlmD"
                     /locus_tag="TVB59_001280"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000902659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEL1010170.1"
                     /translation="MLSKNDIVQVEISDLSHDGLGIAKHEGFVFFVENALPGEIIQMR
                     VLKVNKNSGFGKVETYLTTSPMRQKKLDVTYLRTGIADLGHLLYPQQLLFKQKQVQDS
                     LYKIAGISNVEVKETIGMEYPYAYRNKAQVPVRRVNGQLETGFFRKHSHELVPISDFY
                     IQDKEIDRLIAFTRDLLRRFDIKPYDEKEQSGLIRHLVVRRGHYSGEIMLVLVTTRPK
                     IFRINQMIDSLVAEFPAITSILQNINDKPTNVIFGKAFTRLYGKETITDTILGNQYCI
                     SAQSFYQVNTTMAEKLYQTAIDFSELTADDVVIDAYSGIGTIGLSFAKEVKAVYGVEV
                     IEAAVRDAEKNAALNGITNAYYVADSAENAMANWCQEGIKPTVIIVDPPRKGLTESFI
                     KASAAMQPDKITYISCNPATMARDIKRYEELGYKLQKVQPVDLFPMTHHVETVALLSK
                     LNVDKYISVEIELDELDLTSAESKATYAKIKEYILEKFGFKVSTLYIAQIKRKCGIEL
                     RENYNKSKKDKQVIPQCTPEKEKAIMDALRHFKMI"
     gene            complement(15370..16800)
                     /locus_tag="TVB59_001281"
     CDS             complement(15370..16800)
                     /locus_tag="TVB59_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEL1010171.1"
                     /translation="MTRYQKGGLSHHEELRYFYLLRNLNYLTETERREFTFLKSKMES
                     RAMPSRSQRSLTHYTRGGRDDYAQASQDNADAYDMSDEQQAGPNGLPLYPRSERRSKR
                     HQQKPILAPQQDFYDDPDQAIYEELAPEAMPKKGRRKKKKGRLRRFFRILFFLLLLLV
                     AGIAFMFFKGMMDVSTNKANYKPAVSQVFHGQDTSDGTNILILGSDQRITQGSTDART
                     DTIMVVNVGNKENKIKMVSFMRDTLVNIPGYSYNNQDSYDLKLNASFNLGEQENHQGA
                     EFVRQTLKHNFDIDIKYYVMVDFETFAEAIDTLFPDGVTIDAKFATVNGEAVAAVDVP
                     DDLRMKDGVVPNQTITVGEQKMDGRTLLNYARFRKDDEGDFGRTVRQQQVMAAIMSQI
                     KDPTKLFTGSAAIGKIYALTSTNVSFPFVLKNGVSVLTNGKNGVEHVTIPENGDWIDE
                     YDMYGGQALFIDFAKYQNRLSKLGLR"
     gene            complement(16999..17493)
                     /locus_tag="TVB59_001282"
     CDS             complement(16999..17493)
                     /locus_tag="TVB59_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEL1010172.1"
                     /translation="MTKLLLGFMGVGKTTVAAQLDEHFLDMDRLIEAKIGMSISAFFS
                     YRGEAAFRKLESDTLQEVLALDNETIVSTGGGVVLSKANRELIRKNHKNNILLTASFE
                     ALYDRLKKDRLCQRPLFLNHSEAELYAIFQQRMALYEGLADKVINVEHRTPKEVAAII
                     ANMS"
     gene            complement(17486..18769)
                     /gene="aroA"
                     /locus_tag="TVB59_001283"
     CDS             complement(17486..18769)
                     /gene="aroA"
                     /locus_tag="TVB59_001283"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEL1010173.1"
                     /translation="MKLKTKAKALRGRLRVPGDKSISHRAVIFGAIAEGQTVIHGLLR
                     GQDVLATIQAFRDLGVTIYESADSLIIEGRGFKGLKPAQKPLDMGNSGTSMRLLAGLL
                     AAQDFSVQLLGDDSLSRRPMDRITIPLSLMGAELSGQGEKELPPLIVKGCQELRPIHY
                     QLPVASAQVKSAILLAALQTQGETVILEKELTRNHTEEMIEQFGGKLSVAGKQISIKG
                     PQRLQGQTLQIPGDLSSAAFWLAAGLIVPGSDLVLENVGINPTRTGLLEVIEKMGGRI
                     SYQAVDKDRQAATLKVSYSTLKGIEISGDLIPRLIDELPVIALLATQAQGTTYIRDAQ
                     ELRVKETDRIQAVTDVLGQMGADIQATEDGMVTRGKTPLHGAAVSTCGDHRIGMMTAI
                     AALLVEEGQVTLERAEAILTSYPDFFKDLERLWHD"
     gene            complement(18902..19840)
                     /locus_tag="TVB59_001284"
     CDS             complement(18902..19840)
                     /locus_tag="TVB59_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEL1010174.1"
                     /translation="MSIKKFLDKVISKWQYEPIQAFMRHFQSAEMDLSAIAVAYYLIL
                     TAFPLIVIAANIFPYLNIDISDLLRLMKEQLPKDIYRSASSIVVNIFSKPSGSVLGVA
                     TLTGLWTMSRSLTSLQKAFNKAYDASEHRDFLLGHLVGLLTSLLILFLLTFALIFSTF
                     SKAAIQVLDRHYHLNDNITTLFLFLIQPITILIIFVGLMLLYFLLPNIKIKKIRYILP
                     GTFFTTFVMIFLSNMVGNYVVHNVERMVDIKTFGSVMIFIIMLWFIFLARILIMGAVF
                     NATYQELSIGKLEGRSGNVVSLIKKTLGNDGAPPKK"
     gene            complement(19842..20702)
                     /locus_tag="TVB59_001285"
     CDS             complement(19842..20702)
                     /locus_tag="TVB59_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEL1010175.1"
                     /translation="MITLKSAREIEAMDRAGDFLAGIHIGLRQIIKPGVDMWEVEEYV
                     RRRCKEDNVLPLQIGVDGQLMDYPYATCCGLNDEVAHAFPRHYILQEGDLLKVDMVLS
                     EPLDKAVVDVAALDFDNVAEMKKWTESYTGGLADSCWAYAVGTPSDEVKRLMDVTKEA
                     MYRGIEQAVVGNRIGDIGAAVQQYAESHGYGVVRDLVGHGVGPTMHEEPMVPNYGTAG
                     RGLRLKEGMVLTVEPMINTGTWEINTDMKTGWAHKTLDGGLSCQYEHQFVITKDGPVI
                     LTSQGEERTY"
     gene            complement(20719..22002)
                     /locus_tag="TVB59_001286"
     CDS             complement(20719..22002)
                     /locus_tag="TVB59_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEL1010176.1"
                     /translation="MSKHQDILDYLERLAIGKRVSVRSISNHLKVSDGTAYRAIKEAE
                     NRGIVETKPRSGTVRIEKKGRVRIDRLTYAEIARISDSEVLAGHAGLGHEFSKFSIGA
                     MTQQNIHRYLIKGGLLIVGDRENIQLLALKNHNAILVTGGFPVSKQVIETADSQGIPV
                     MVTHYDTFTVATMINHALSNIRIKTDLKTVAQVLIPVEEYGCLYETDTVEEFNALIKK
                     TGQVRFPIVDALDQVVGVVSMRDVVDQPAETRLEQVMSPNPITAKPNASLANISQKMI
                     FEDLNMLPVVDDHHFLLGIITRRQAMENLPNHQPGNLYTYSQQMLSSLEETLDYYQVM
                     IEPTMIDSAGNLSNGVVAEFLKEISVRVLTKKHQKNIIIEQMMIYFLHAVQIDDQLRI
                     YPKIITENRRSSTLDMEVMVDDQVIAKAIITTKLN"
     gene            complement(21995..22549)
                     /locus_tag="TVB59_001287"
     CDS             complement(21995..22549)
                     /locus_tag="TVB59_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1010177.1"
                     /translation="MDIWTQLARFAFVETQRLLLRPFQYADHQPFYDMISHNSHYQFV
                     FPESMTKAESDFLMVNAFMKEPLGVWLIEDKTSHSMLGSIRLEKYDKQQASAEIGYFL
                     AQPFWGQGLMTEVLKTLTFLAFQEFGLRQLIIVTHLENKASQRVAEKAGFRLTKQFKG
                     SDRHSHHIRDYLEYQLTIGEYHYE"
     gene            complement(22843..24132)
                     /locus_tag="TVB59_001288"
     CDS             complement(22843..24132)
                     /locus_tag="TVB59_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622582.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEL1010178.1"
                     /translation="MEKNKKVSYFLRQSAVGLASVSAAFLVGTTSVGALDAATVLEPT
                     TAFIREAVREINQLSDDYADNQELQAVLANAGVEALAADTVDQAKAALDKAKAAVAGV
                     QLDEARREAYRTINALSDQHKSDQKVQLALVAAAAKVADAASVDQVNAAINDAHTAIA
                     DITGAALLEAKEAAINELKQYGISDYYVTLINKAKTVEGVNALKAEILSALPSSEVID
                     AAELTPALTSYKLVIKGATFSGETATKAVDAAVAEQTFRDYANKNGVDGVWAYDAATK
                     TFTVTEQPVAETIEAAELTPALTTYRLVIKGVTFSGETATKAVDAATAEQTFRQYAND
                     NGVTGEWAYDAATKTFTVTEALEESPADPEKPSASLPLTPLTPATKTAPAKQKDKQKA
                     KTLPTTGEKANPFFTAAALAIMASAGALAVTSKRQQD"
BASE COUNT         6485 a         5524 c         3924 g         8246 t
ORIGIN      
        1 gcattaaagc aaagctaaaa ggacttagcc ctgtgcaata cagaactaaa tcctttcaat
       61 aattattcgt ccaacttttt gggggcagta catttagtaa tcttttcttt ttgaatgaca
      121 tcagttattt caatcttatt gcccactaaa gttaagagct gctctgctgc tatttcatca
      181 tcaattctat ctgttgaaag tgtaaagcta tttgtagaaa gctctaccgt ataatatttt
      241 tctttcttaa agtttgctat ctcatcatct ctttttacga tcatagcaag agtcggtgtt
      301 tgtactctgc caacactgta attttgctta tacagacaag aatagagcct gctgatattc
      361 attccgacaa gccagtcagc gatagctctt gcctgtgccg actcaaagag attatcgtaa
      421 tcttttccgt cttttagatg atcaaagcca tctttaatgg cagtatcttc catagatgaa
      481 atccaaaggt gtttcatctt ctttttacaa ttcacttgat tatatacaag tctaaaaatg
      541 ctctcccctt ctctacctgc atcgcacgca ttgataaccg tatcaatttc tttgtcgttc
      601 atcaactttt taaggatgtt aaattgtttc ttggttgact ttgccacttc atacttatag
      661 tccttgggga taatcggtaa atcaaccata ttccacttgg catacttttc atcataaaca
      721 tccggatttg ccatttgaat taagtgtcca acacaccaag atactttgta tccatttccc
      781 tcataatatc cgtctttctt tttatttgct ccaagtactt ttgcaatact taatgctaca
      841 cttggttttt ctgcaatgac taacttcatt tctgtactgc ctcctgtttt caatataaaa
      901 gggcgaaaga ttttattctc ccgccctgca tttgcaccaa atactgtatt tttttggtgc
      961 agcattactg ctcatcttcc gcttctactt catctacatc atttgtttct tcctcgcttt
     1021 cagcttcaga aaagaaatca tcatcttctt cctctaatgc ttcaagctcc ttatcttctt
     1081 tcttttttac aaccttaaag tagtatcctg ctcccaatgc tccgcctaca acaagaagca
     1141 gaataatata tgttcctaaa ttactctttt cttctttttt ctcaggcttt acttcttcct
     1201 taacaggttc ttcttttaca atctcctgct ttggagcttc ttttttctct accatgttaa
     1261 gcaaatcatc ttcggatact tctgtaagaa gcatgacatt ctcactatcc tcatcgtggt
     1321 tgatgatgag atgaaaggtc ttaccgtttt tagtttgaaa ggtaataaac tgtcttgcat
     1381 cagcggaata ttgatccgtt tctttattat cgctgctatc cccatgatga atcggataat
     1441 ctttatttcc attatcttta ttttctgtaa cagttcctct tgcctttgac ggagatgaag
     1501 ctactccctt attggtattt acattactac ttgccccctc cattgacgaa tcttgactgc
     1561 tgttattagc aggtgctttt gctgtcaatt tattagaata gcgaacttcc ttttctttct
     1621 cctttacttc tgttttgctt gtatcctttg tagcattccc tgaactcacc gtatcagatg
     1681 agcctttacc ggaactactt acagaagtct gtggtgtttg gggagaaatg cttgagcttg
     1741 tcttaattcc ggaaatagga ctaatcggtg taacagaatt tattgcttca gaagatttct
     1801 ttgtttcagt tgcctttttc tcaagctctt tcaccttatc agtcagctta tctatttcct
     1861 ttttcatatc ttctgataag tccttatttc ctttatcttt cttcattttc tctttcaggc
     1921 tgtcaatttc atcttcaagg tctttgattt tttctttctg cttatccttg tctttaagct
     1981 caccatttaa cttatcaaat ttttcttgaa gctctttagc ctctttttcc atcttagaaa
     2041 tatcgtcttt agaaagctct gtctgtgtgc ctttatcctc cgtttttgta gcttctgttt
     2101 gcgtgctttc gtcctgcttt ggtttttctt cttccgtttg cgtttcctta tccttaacct
     2161 cagtctttgc taccttacgg ataatttcat catttccatc tccctttact tcataaaaca
     2221 ggaattcatc aataaatttc atatcatcag ggagcattgg aagatcgcca ctatcaagaa
     2281 gctgtccttt ctctgcctta atcttttctt ccttaaatac cttttcatct tcaaagatat
     2341 actttacatt tacttcaact tccgtttgga cagcttcgtt ttttgtagga gcgtcagagc
     2401 ttttctcctt ggcgtaaaca accgtccaaa gtcctaaaat gcagctaata cttacaatta
     2461 ctgcaagtgc tgctgtccaa aacttattat tctttttcaa actggttttc atttgtcctc
     2521 tcctttttca gttctgcttt ttctctgttt acctttgtca ttaaatcaga aattgtgatg
     2581 ttgttctttc tgcaaatcat gatgatttct tcattttcaa gttcttcttc acgaataaat
     2641 aaaggctcca attcttcatc aatcagagcc tttttatcct ttaacttttt tattctgttt
     2701 tttactgctg tcagttcttt tttcatattg ttccctcctt atctgtttac atttggtgga
     2761 aaaccaaagc ctaccggatg gtgtttacaa aaagtcgcaa tccaatcatc taaagtagtt
     2821 actcttatat aaccgatatt atcaataacc ttgccgtctc cgatatagat tccgacatga
     2881 ccataggtaa gtcctgctgt gcttccgcta ctgctgcttt ctaccgctac aagcattcct
     2941 accttgagct ttgacctatc ggatgtaaag gtatagtttc gatacatatc attagcattt
     3001 cctccgatat atccaagtcc cgcattttgg taaacttgcg atacccacat ggcacaccag
     3061 cctgcacccg gagatggagt gatatatgca gcattaacaa tcttcttttg tacttccgaa
     3121 gatgcctcat actctttccc accacctaca ccgccattag cactgataag gtcagaattt
     3181 ctaaaggctt ctcccatatt tccttgagca aggaataagg cttcatagtg ctttaaatta
     3241 tcgggatagt ctttaaagac ccttcggata atgctgtcca tctctttttt atgaagcgtt
     3301 acaatgagct tcttatattc ataaggctct tcatggcttt cggtatattc attgccatct
     3361 tcatcggtat aggtttctgt aactgtcctg tatctgattt caatttcttc cctgtattca
     3421 aggtcataca tggactcaaa caattctttt aatatggttt ctacttccga tacactcttt
     3481 acctctccgc accttgatgt aatgtaggat aaaagctcat ggacattatg accgatatac
     3541 tctgtgttgt ttaagatata ctcatcatat ccgggataat tctcttctac atgatccact
     3601 tcactttgaa gctcactctc catagcagaa aacttctgat tgatttcact tagaacattt
     3661 ggctttgata aatagcttgt tgtaagaaca gagtttgtag agttcataaa gcctgtcatg
     3721 cctgttcctg caaagttaat cacaaaattt cctaagatga tgatacctac gaagataagc
     3781 attagtcctt tggcttttcg gataatcata tcctttgagc ttttcagtgt tccgataagt
     3841 ccctctttaa tccgatctct gagtcttgac ttattctcac gagaaatcgc tgcctttacc
     3901 tgatttttct tttgaaatct tttataggca cttgctcttt tatactcatc tgtctttttc
     3961 agttcctctt tggcatcacg aaactctaac ttggatttac gctttctgat tttatagtcc
     4021 ttatttgtaa gctcatatcc ttttttagct cttttcttat ctgagtatct ctttatacca
     4081 tgaatgagtt ttgaacttgc atcggctgtt ttttctcccg cttctacgcc tttattttca
     4141 tcacttccat gagaaaggta atctcttacg gtttcacttc ctttggcaag tcctgacagg
     4201 gcagatactt ttaccatatc tttcttcagc tttttctttt ggtcttttga aagactgcta
     4261 tgttcttttt cgcccgcaac atctttccct gcctttttat cttcaggctt attctctttt
     4321 ggtacatcgt ccttttttct tgtatagagg ctttcggaat agtttttcct tttatactta
     4381 ttcttttgag ccttatgatt tttagaggga ttttctaatg atttttcttt ttgaggtaga
     4441 ttatcctcta catcataggt tgattcaaag tagtcgctgt ccctaaaatc attatcgtat
     4501 ctgtctatga ttccatcatt atcaaggtct tgtcctaaag aatcatagat tttcccgttc
     4561 tttacctcag tatcatagtc agcctttcct gcttcattta cacttccctt atcagaagcc
     4621 ctatactttg catttctttt agaagtcccc tctatctgct cattttcaga tcttaccttg
     4681 cttatcttct catgaacctt gtcctgaaat ctatctttgt catggacaat ttttcctctg
     4741 taatcatcgt tatgctttag cttactttct tcaggtatag agcttgtttc agctttaagc
     4801 atctcccttt caaggcttgc cttatgcctt tctctaaaat cttttttcag cttcccatcc
     4861 ataagctacc tcacttcttc aggcttggta gtcatcttct gataaagaat tgtatctttc
     4921 ggaaacttat caaggaaagg cacaatggta tttccaaaga aaagtagtcc ctcgccctca
     4981 ttggagttcg taacatatct aagctgcgga agtgagattt taagtttcct tgcaagtatt
     5041 tccctatctc ccgaagcctg atttaacatt aagacaaagt ccgtattatc aaagatattt
     5101 tcaatttcct tactcataag taggtctttg acattttgcg tgataccagt cgggattcct
     5161 ccccattttc taaaacgctt ccaaatctct accgaatatg aagctgtctg ctcatctttt
     5221 aacagcaagt gaaactcatc tatatagtac cttgtagcct tgtttcctct gttttgcgat
     5281 accttattcc acacctgatc ctgtataaca agcataccta ttttctttaa ttgacttcca
     5341 agctccttaa tatcaaaaca aagtagcttc ttatttaagt ccacatttga cctgtgatta
     5401 aagacattaa gagaacctga aacataaatt tccatctctg ttgccagctt tttccctacc
     5461 ttttcttcct gcccttttaa catatcgtat aggtcttgaa gtataggcat attgtcataa
     5521 gtcggatttt caaagtacct ttcgtaaatc ttaggtaagc atctatctat aacggacttt
     5581 tcttccgctg taagtccact accaccaact acaagctcaa gcatagacat aatgaagttt
     5641 gccttgtctt taagaggtgc gtccccatca ccgtagttca tatttatatc aagtggattc
     5701 aggtaatctt ttgacttact gctgacctta atgacttctc cattaaactg tcttacaagg
     5761 tttccatact ctccctccgg atcacagata atcacatcat cgtccgttac taaaatcgca
     5821 tttgccatct ctcttttggc actaaaggac ttaccactac ccggagttcc taagattaga
     5881 ccgtttgggt tctttaattt ctttcgatcc gccataatca ggttatggct taaagcgttt
     5941 agtccatagt ataggctatt acttgaattg ataaaaagct cctctgttgt aaaaggcata
     6001 aagactgctg ttgatgatga ggttagccct ctatctattt caatcttgtt taccccaaga
     6061 ggcagcacgc tcactaagcc ttgttcctgc gtatggtcaa gtcttttcaa tttacagtta
     6121 tgcttgtttg caatggagct tatctgagct atggtgttat cgagcttttg cactgtcctt
     6181 gcaaaattca taaagacaat acttacaaca aacatacgct catctcttgt ctgtaaatct
     6241 tttaaaagac tttttacatc ttctccgtaa gtaattaaat cacttggaag aatgtccatg
     6301 tcatagcctg accttacagc tttcttgttt tcctcaattc gcatcttatc aatatcggtg
     6361 ttttttcgtt ttaccatctt gatggcttct gactggtcaa tcgccttaat atgaaaagat
     6421 atattgatgt tatcatcaat atccaaaaac tccgataaca tacggtctga aagctcactt
     6481 gcaaggattt gaaaatgact tgttgctccg ataaacttcc caaacttgaa atacctgctt
     6541 ggcataaagt taaattcatc aggcacgata tatgttttgg tactttcctt tttcttcagg
     6601 tctttgtagg aaaactcaaa ggtcttattc ggatttaata tatcgtgaag aatctttagc
     6661 ctttcctcta ctgtaagact ttcagctctt acccccatgc ttttgagatt agataatata
     6721 tctatatcca atctttcaag ttttgatgta gcctgttcta aattgtctgc ctctactgta
     6781 aaggttacat actttgattt tttcagtccg ttatttcctt ttacaatctg actttttagc
     6841 atctctctaa actcaagtcg tatatcgtca aatccgtccc ctttatccgg tatctgaatt
     6901 gccgatttca tttcttcgtt tcgtccaagc tgattgatgt aggaaaactc aatcgctatg
     6961 cttggatcaa aggaatttag aaagtttgca aactgattaa aaatcaaatc cctatcttca
     7021 tctaaagcaa gctgatagtt aatgtcctga aaggctatgc ttttactgaa gtgcttttca
     7081 tcgagctggc atatcccgct ttttaagagt ctaagatagg gaatggtatc ttctaccgta
     7141 tagcgttttt gctcttttct aaagataaga tcaagtagtc cgctcttttc tttgttagac
     7201 tttcccttac tttgctttaa gtcctttctc tcctttttta atgccttttt gttttcttct
     7261 aactttagtt gctgaatttt tcttttcttg ttcaaggtaa acctcctttc tcactctctt
     7321 tgccggctga taaaacttat gaaggtagat atgcttaaaa tatttctcaa aggtcagtcc
     7381 gtccttttca aaaagtgtga taaaaaagat tggaagtgtg gacacgataa ggaatatgaa
     7441 agctatatcg tttggtacta cctttctcat aaataaatag acaggtattc caacaagtcc
     7501 tgcaatggta aatcctatga gctgtctttt tgtaaggtta aaggctacct ttgtcttgac
     7561 cttctttaag tccttgggta ttggtacata cgccatagct tacctcccat cttctttacc
     7621 ctttgaaaac tcctcaaagt gttcatatac agagccgatt tcatcctgaa taattgcaag
     7681 ctgttcatct gtattcttgt tatatctttg ctgcattaag caaaaatcat tatggcagcg
     7741 accgatgtcc tgtgttcttt cttctaattc ggcagctttg ttatgaagcc tgattctatc
     7801 aattaccgcc ataatgcctg cgaccattac tactgctgta aatactgttt ttcttttatt
     7861 catactatct ttcctttctt ttttagtgtg catttaatac gcttttggcc agtgttccgc
     7921 tctttagcat cattaacccc agcaaaaccg cataaccaag tatcgtcatg gtacttgtgt
     7981 gtatatctgt tatttcaatc gtcttaacta atactgcgta aattccaaga caaaccatta
     8041 aaaagagtcc ttgtagtcca agtgcaaata atcctttgat gtaatttgtg ccaatttgcc
     8101 cccattcttt gtttcccatc gtggcaaatg gaatggctga aaccgatgaa taaacataaa
     8161 tctcaaacat ccttccgtaa accacaagca taatcactat ggaaattgcc tgtatggcaa
     8221 ctttaatgag cgaggtttca aagagaatca tgataagctc tccaagtccc ttttctttta
     8281 gggtatccat catcgccact atctgatctc cggaaacggt ggcagaggtg tttatcaccc
     8341 ctgccgcctt atttaccata tgctgtgcta catcaaagac cgccattgaa aattcaaaag
     8401 cgtgagatac caaccataca gcaattcaca tcttgatgat gtacttgaaa aattcaaatg
     8461 tatccgtatt atcatgtagg ttatttttct gtataaccat attgataagc tcgatacaaa
     8521 ggactgctgt gataattagt cccgctatgg gaataatgac cgaatcgtta atgcttttaa
     8581 taaaggtaaa tacatctcca ttccacccca taggagtttt tcctacatct gttgcaactg
     8641 caccaacctt gtcgttgatg tcaagaaaca tggactctaa gtttgcttgg ataccgccca
     8701 gtagaagctc cttaaagaat tcttctattt tgtcgaatat cccaaacatc taagctctcc
     8761 ttttcttctt atctgagtac atttgcaaga agtggaatca gcttaagtcc gataaggaca
     8821 atacctcctc ccgccatcaa ttgcttgatc ccttgacttt tggctcccgg attatcgtta
     8881 ccataacctt ccatcaggtt aatgacaccc catgctccaa gtcctgctcc tactgccata
     8941 accaaaatct ttaatacatt tactgcctgt gcgaaaaatt ccataattta ttcctcctca
     9001 ttttcttctt tcttttcaat cttgttgtat gacttcacta caaaattttt gtaagtcttt
     9061 ccctcttttt cacgcttctt aaagtagccg aatacatgaa tcaaatcgcc cttttcaaag
     9121 tcctttgctt tatccgcttt ttctccatag gctgcacaat tgatgtactc cttgccttta
     9181 ccgtacttct ttacaagcgt aaaatttaca acttctactt ctttaccctc tttttcaaaa
     9241 cttgagaaag taggttctgc cactaagttg gcgttgatgt taatcatttc ttgcttcatt
     9301 aaaaatttct ccttttcatt tcaataaaaa aagcgaccgg aagtattact tttccaatcg
     9361 ctatactcat actatttagt tttttactca gtgggacttc tgatccttat catcttgcct
     9421 ccttactttt gcataaaaaa gcagcaaatc tattttgtag acttactgca ttcttgtaat
     9481 aactgtttcc ctattcagtt ttgcttttcc tttccgtttc atgtagcttt ctatatcaaa
     9541 taaatttttc ttatcatagt cctcaagcag cttatagttc ttgtgctttg taatatcgta
     9601 cttatctgaa agaaaaggtc tgacacctct aagctgaaag atacattttc caccatccat
     9661 gaccgtaatc tcatcctgac tcatcagctc tttgcctgtt ttttgatagt taagtccaaa
     9721 gctcttttga tttgaccttg tttccgatgt gttgtaaagg tcgatagttt ctttaccaag
     9781 cgtttcggac agctctttta gtgttttttt cctttccacc taagaataag gtactatcac
     9841 agttacccac aatggtatca gcattatcct tatatattgc ctttagctga gattgtgcct
     9901 gtaagataat actcgctgaa atttctctac ttctaattgt ggctatgagc ttctcaaact
     9961 ttggaattaa gccgatattt gcaaactcat caagtaagca tcttacatga acaggaagtc
    10021 tgccaccata tacatcatcc gccttatcgc aaagtagatt aaataactgt gaatacataa
    10081 tagacactac aaagttaaag gtatcatctg tatcagagat aataacaaag agtgctgtct
    10141 ttctatctcc caatgtatca agctcaagtt cgtcttcact catcaaatct ctaagttcct
    10201 gaatatcaaa tggagcaagc cttgcaccac aagatataag aatagatttt gctgtctttc
    10261 ccgcagccaa tttatatttt ttatattgct tgaccgcaaa gtgcgtaggc tcctttttct
    10321 caagtgcttc aaagagtctg tctattggat tcatataggt ttcatcatct tctcttactt
    10381 ctgaagcgtc tatcatatca aggagcgttg caaagttctt ttcttctctt ggagcttcat
    10441 agaagatata tccgataagt gctgtgtagt agagtttttc cgctttgacc caaaaatctt
    10501 cacccgcttt ttctccctca ccttttgtat ttgcaatgat tgtctgcact aatttgagta
    10561 tatctttctc agaatggata taggcaaagg gattgtattt catgctcttt ttgaagttta
    10621 tggtatttag aatttttatc tcatatccat tgtcttcaag catcttgcca cattcaatga
    10681 ctatcgttcc tttcggatcg gttacgcaat agctactgtg catctgcata aggttcggtt
    10741 ttacataaaa tcttgtctta ccacttcctg atccaccgat tacaagtaca ttcttgttac
    10801 gagcatactt tggattagcc ggtctaccat tcatagttag gcgttctgtc tgggtaagca
    10861 agatattgtt ttgaaacttt tcatccatgt atggctcaat atctttctta tttccccatc
    10921 ttgctgagcc atactctttc ccctgtctaa actttttagc attttacctt tggtatagac
    10981 aataaattta attaaagcag ccattcctat gcccattaaa atatccgccg gatgaatact
    11041 tggaagaaaa ctcatcgtgt tgatctccaa tatcccttga aagattttat ctatgacatc
    11101 accaccggta tagcttctca catgatgggc aaagatgttt cctaaataga aaaatgcaag
    11161 atagggaatg ttttgcttta caaactttgt cttatcctgc accttaaata agcctttgat
    11221 gtcctttaat attttatcta tcataggctc tgctcctttt gtttattctt gattttatct
    11281 ttggaaacag agttcttagc catttcctta aacttctcaa tattcttgtg aatagattct
    11341 ttcctttccg ttttcttttc agactgtgct aatgcgtgct taaaggcttt atccatcact
    11401 ttcatatctt tggcttgaaa gaatacagag tattttcctg tttccttatc cttcatcact
    11461 gaaaacttaa caccataccg attaagttct tttttcagtt ccttaagctc cgcttcttca
    11521 acaggaattt cttcaagctg tccctttttt accatatctt ttagctttac ttcatttccg
    11581 ttagcattaa ccagcttttc aagtcctcca agtttttctg cttctttcat caatttcttt
    11641 aataagttca gaattaactt tcctgttact ttagcagctc ttacttccat attcagcgtt
    11701 tttcttgcta tttcttcatt gatcaagttc tctcacctcc attcagtaac ctatctttat
    11761 ttcgattcaa tttatctctt tgaataatct ttctaaaatc ctctttggat tgtgtcgtag
    11821 gaaaggttag tggtgaagat agtcggtttc tgctttaagt acctgttgtt gacaatgtta
    11881 tatacctgct ctttggcata gcttgtatct ctttctattc ccaagtcatc caagataaga
    11941 acggaagtat ttacaaggga ttcaatatat gcgttcttat caaaatcaaa tcctcccttt
    12001 tgcagctcat tgataagctg tgcaaaattt cttattttaa cgcctatttg atactgttca
    12061 ataaggctat ttgcaatgga gcaggcaaga taggtttttc cacttcctac tgagccgtaa
    12121 aatagcagtc cgatattttc ttttttcatc tgctcatagt cttttacaaa attctttgca
    12181 atgataagac tttgattttc ttctccctga taattttcaa aggtgtatga ccactgaata
    12241 atagagttaa agcagttctt ttttaatcgt tctatttcca tctgcttttc tctttctttt
    12301 tttcttgcct ctctatctct atcgcatttg caagaaatct taaatatcat cttgttatca
    12361 aagaactcca tcacttttct gtcttttctt tcatgacaaa ctttacaaaa ggcgtgtccg
    12421 tccttgatat attctttttc aggatcgtaa gaatactcta catcctctat cattactttt
    12481 tctaattctt ttatcatagg tgttctcctt tatcatattc ttcccatgtc gggatatttg
    12541 atgttttcac ttctttgccc cttccctgat ctttataaaa ccatgaaagg attgttgcct
    12601 tatggtcttt ataggtcttt ccggtgcttt taatatatgc agataatctc tcaatataat
    12661 tatcaagctg tgagttcatt atgatttgta agtctgatat atcttcagca gctaaaaaca
    12721 cattttgaaa tgttccaagc ccgttttcac taaaattata ttctctctta ctatacttac
    12781 tcttattatt ctctatatag ttagagtcaa ggttcttaac ctcttgaagt tcattttctt
    12841 tacttctgag gttaaaatct tttacttctg aagtaaaatt ttttaacttc tgtaagtcat
    12901 cttcttttac ctgaaatatg ctcataaaat ctttgacata aatgatattc ggctttccaa
    12961 gtccaagccg tacccgttca atcagtccaa ttcctttttt actatctaat tcatctaatg
    13021 tttttatggc agtcggcttt gagatatttc ttcttttcat aatttcttcg actgtgaaat
    13081 agataaatac cctgccttcc ttatcaatcc agttattctt aaaggacatt cctgtccgtt
    13141 taagaagcat tgaataaagg ataattgctt cagcggataa tcctttaaat tcttctccat
    13201 caaccaatat ctccggtact tttaagaaat taaatctttc cgcttctctg ttataaaaat
    13261 agtcaaagtc catcgcttca cctccctcct taaaaatttg caaagaaaaa gacgatagtt
    13321 tttctctatc gcctttggta accattttta tgaaattttt tagattgatt ttattgcttc
    13381 attgattcct ttaaagaatg ctataactgc tgctccaacc atcggtattc cataaggact
    13441 taacaaaaat cctaatacta atgcctcaat gccaagtgat atatcttttt gcataaatga
    13501 tcctattgca gcaactatac acatcagcat taagaaatac agaatagttg ttcctatgcc
    13561 aagtataaat gtcagaaagg cagtaaggac actaagtagc aagctgaatg gaaacaatat
    13621 tatttttatt atccacctca tataatacct ctcctttctc ttaaatcatt ttaaagtgcc
    13681 ttaacgcatc cataatagct ttttctttct caggtgtaca ctgcggaata acttgcttat
    13741 ctttttttga tttattgtaa ttctctctaa gttctattcc acattttctt tttatctgtg
    13801 ctatatatag tgttgaaact ttaaaaccaa atttttctaa tatatactct ttaattttag
    13861 cataggtagc cttgctttct gcacttgtca aatcaagttc atcaagctct atttcaacac
    13921 ttatatactt atcgacatta agtttggaca ataatgctac cgtctcgaca tgatgtgtca
    13981 ttggaaacaa gtctactggc tggactttct ggagtttata gccgagttcc tcgtagcgct
    14041 tgatgtcacg cgccatggtg gcggggttgc aggatatata ggttattttg tcaggctgca
    14101 tcgctgcact ggccttgata aagctctcag ttagtccctt tcgtgggggg tctacaatga
    14161 taactgttgg ctttatgccc tcctgacacc agtttgccat cgcattttca gcgctgtcag
    14221 cgacatagta ggcattggta ataccgttta gcgctgcatt tttctcggca tcacgcactg
    14281 ctgcttcgat cacttcgaca ccgtatactg ctttgacttc tttagcaaag gatagcccga
    14341 tggttccaat gcctgaatag gcatcaatca ccacatcgtc agcggtcaat tcagaaaaat
    14401 caatagctgt ttgatagagc ttttcagcca ttgttgtatt gacctgatag aaggactgag
    14461 cagaaataca gtattgattg cccaagatcg tatctgtgat tgtctctttt ccataaagcc
    14521 ttgtaaacgc cttaccaaag ataacattag taggcttgtc attgatattt tgcaggatag
    14581 aagtaatcgc tggaaattct gcgacaaggc tatcaatcat ctggttgata cgaaagattt
    14641 taggtcgtgt tgtcactaaa accagcatga tttctcctga ataatgccca cgacgaacca
    14701 caagatgacg aatcaggcct gactgctcct tttcgtcata gggcttgatg tcaaaacggc
    14761 gcaaaaggtc gcgtgtaaag gcaatcaagc gatcaatttc cttatcttga atgtaaaaat
    14821 cagaaatcgg cactagctca tgagaatgct tacggaaaaa accagtctct agctgaccat
    14881 tgacacgacg aacaggaacc tgggctttat ttcgataagc ataaggatat tccataccaa
    14941 ttgtttcttt gacctcaaca ttgctaatcc ctgcaatctt atagagacta tcctgaacct
    15001 gcttttgctt aaagagcagc tgctgcggat aaagcaagtg ccccaaatca gcaatacctg
    15061 tacgcagata ggtcacatcc agcttttttt gacgcatcgg tgaggttgtt agataggtct
    15121 ctaccttgcc aaagccactg tttttattga cctttaggac acgcatctga atgatctcac
    15181 ctggaagagc attttcaaca aagaaaacaa agccttcatg cttagcgatt cctaagccat
    15241 catggcttaa atcagaaatt tccacctgaa caatatcgtt tttacttaac atttactttc
    15301 cttttctttt actacactaa tcactcaaaa aagaagagca accatcgtta cccttcatta
    15361 tagcatatct tagcgtaatc ccagcttaga taatcgattt tgatacttag caaaatcaat
    15421 aaagagagcc tgaccaccat acatgtcata ttcatcaatc caatccccat tttcaggaat
    15481 cgtcacatgc tccacaccgt ttttgccatt agtcaagacg gacactccat ttttaaggac
    15541 aaatgggaag gagacattgg ttgaggttag ggcataaatc ttaccaatag ctgctgagcc
    15601 cgtaaagagc ttggttggat ccttgatttg agacatgata gcagccatca cctgctgctg
    15661 acgtacggtc cgaccaaaat caccctcatc gtcctttcgg aagcgagcat agttgagcag
    15721 ggtacgacca tccatttttt gctcaccaac cgttatggtt tggttgggaa ccactccgtc
    15781 tttcattcgt aaatcatctg gtacatcaac agcagcgact gcttcgccat ttacagtagc
    15841 aaatttggca tcaatggtaa caccatctgg aaacagtgtg tcaatagcct cagcaaaggt
    15901 ttcaaagtca accatgacat aatatttaat gtcaatatca aaattatgct tgagtgtctg
    15961 acgcacaaat tctgctcctt gatgattttc ctgctctcct aaattaaagg aggcgttcaa
    16021 ttttaaatca taggaatcct gattattata gctatagcca ggaatattaa ccaaggtatc
    16081 cctcatgaag gagaccattt tgattttatt ctccttattg ccaacattaa ccaccatgat
    16141 tgtatctgtt cgagcatctg ttgagccttg cgtaatcctc tggtctgagc ctagaattaa
    16201 aatattagtg ccatcgctag tatcctgacc atgaaagacc tgcgaaactg ctggcttata
    16261 attggccttg ttagtagaca cgtccatcat tcccttgaaa aacatgaaag ctatccctgc
    16321 aacaagcagc agcaacaaga aaaagagtat tctgaaaaaa cgtctcagac gtcccttctt
    16381 ttttttcctt ctaccctttt taggcatagc ctcaggcgca agctcctcat agatcgcctg
    16441 atctgggtca tcatagaagt cctgctgagg ggctagtatt ggcttttgct gatgcctttt
    16501 gctacgtctt tctgatcttg gataaagagg caggccatta ggcccagcct gctgctcatc
    16561 actcatatca taagcatcag cattatcctg tgaagcttga gcataatcgt cacgcccacc
    16621 cctagtataa tgagtcaagg agcgctgaga acgagaaggc atagcccttg actccatctt
    16681 tgactttaaa aaggtaaatt ctctgcgttc agtctcagtc aaataattta aatttcttaa
    16741 taaataaaaa tatcgtaatt cttcgtggtg gcttagacca cccttttggt atctcgtcat
    16801 gctcttccaa ctcttagtat tctaatacaa tttcttctat tctttgtcta atgattctat
    16861 tataacctat attaacgaga ttgtcctcta aaatcgttag aattcaactt tatttcaacc
    16921 tatatattag cttttcatac ctaatcatta agaaaagctg ggctgcgaat aggaggccaa
    16981 aagtctaatc ctcagcagtt acgacatatt ggcaatgatt gctgcaacct cctttggtgt
    17041 tctatgctca acattaatca ctttgtctgc caatccctca tacaaggcca tgcgctgctg
    17101 aaaaatagca tagagttctg cttcagaatg atttaaaaac agtggtcttt ggcatagcct
    17161 atctttttta agccgatcat acaaagcctc aaaggaggct gttaagagga tattattttt
    17221 gtgatttttt ctgattaatt ctcggtttgc cttactaagg acaacacctc caccagttga
    17281 tacgatagtc tcattatcaa gtgccagcac ttcctgtaag gtatctgact caagctttct
    17341 aaaggctgct tcaccacgat aggaaaaaaa tgctgatatg ctcatgccta ttttagcctc
    17401 aataagccta tccatatcca aaaaatgctc atctaattgg gctgcaactg tcgtcttgcc
    17461 aactcccata aatcctaata gcagcttagt catgccataa cctctctaaa tccttaaaaa
    17521 agtcaggata agaagtcagg atagcttctg ctcgctctag ggtgacctgt ccttcttcaa
    17581 ccagtagggc tgcaatagct gtcatcatgc caattctatg atctccacag gtactgacag
    17641 ctgcaccatg taatggtgtt ttgcctctag tcaccatacc gtcctctgtc gcctgaatat
    17701 cagcacccat ctgtcctaat acatcagtaa cagcctgaat gcggtcagtt tccttgaccc
    17761 gtaattcttg agcgtccctg atataagtcg ttccctgtgc ctgagttgcc agcaaagcaa
    17821 taacaggcaa ttcgtcaatc aagcgaggaa tcaagtcacc agaaatctca atgcccttta
    17881 gggtggaata agacactttt agggtagcag cctgcctgtc cttatcaaca gcctgatagg
    17941 agatacgacc acccattttt tcaatgacct ctaaaagacc tgtccgcgta ggattaatcc
    18001 ctacattttc gagcacaaga tctgaccccg gaacaatcag accagcagct aaccaaaagg
    18061 ctgcgctaga gagatcgcca ggaatctgta aggtctgtcc ctgcaaacgc tgcggtcctt
    18121 tgatactgat ttgctttcca gctactgaga gctttcctcc aaattgttca atcatctctt
    18181 cggtatgatt tcttgtcaat tccttttcaa ggataacagt ctctccctgt gtctgcaaag
    18241 cagctaataa aatagcagac ttgacctgag cagacgctac aggcagctga taatggatcg
    18301 gccgcaactc ctgacagccc tttacaatta gtggtggaag ctctttttct ccttgaccag
    18361 atagctctgc tcccattaga gacaatggta tggtaatacg atccatagga cgccttgata
    18421 ggctatcatc tccaagcagc tgcaccgaaa aatcctgtgc tgctaatagc cctgcaagca
    18481 ggcgcataga agtacctgaa ttgcccatgt ctagaggctt ttgagctggc tttaggcctt
    18541 taaaacctct tccttcaatg attaaactat cagctgactc gtaaatggtg acacctaggt
    18601 ctcgaaaggc ttgaatggtg gctaaaacat cttgccccct taaaagacca tgaatcaccg
    18661 tttgcccctc tgctatagca ccaaaaatga ctgcacgatg gctaattgac ttgtcacctg
    18721 gtacccttag acgtccccta agcgccttag cttttgtttt taatttcatc attactccta
    18781 tttttagtac accagcatta gctcagcaaa gcaaataaaa gaaaatgaag taaggacaag
    18841 ggcccttacc ccatcaacta atcaccaagc accgtcttgt ttttcattct aagacaagcc
    18901 gctatttctt gggcggcgca ccatcattgc ctaatgtctt tttgatgaga gaaacaacat
    18961 tgccgctgcg cccctctaat ttgccgatgg atagctcttg ataggtagcg ttaaaaaccg
    19021 cccccataat caatatcctt gccaggaaaa taaaccatag catgatgata aaaatcatca
    19081 ccgaaccaaa ggttttaata tcgaccattc gctccacatt atgcaccaca taattaccaa
    19141 ccatattgct caaaaaaatc atgacaaagg tggtaaaaaa tgttcctggt aagatatacc
    19201 tgattttctt gattttgata tttggcaaca aaaaataaag caacatcaga ccaacaaata
    19261 taatcagtat cgtaatcggc tgaatcagga acaaaaagag cgtcgtgatg ttatcattta
    19321 agtgataatg cctatccagc acctgaatcg ctgccttaga aaaggttgaa aaaatcaagg
    19381 caaaggtcaa caaaaacagg atcagcaggc tcgtcagcaa gcctaccaaa tgaccgagca
    19441 aaaagtcacg atgctcagaa gcatcataag ccttattaaa ggccttttgc agagaggtta
    19501 ggcttcgcga cattgtccaa agccccgtca aggtcgctac tcccagcaca ctgcctgatg
    19561 gcttagaaaa aatattaacc acaatggagg aggcagagcg ataaatatcc ttaggcagct
    19621 gctccttcat taagcgtaat aaatctgaaa tatcaatatt taaataagga aaaatattag
    19681 ccgcaatgac aatgagtgga aaggctgtca aaataaggta ataagcaact gcaatcgctg
    19741 acaaatccat ctctgcactc tgaaaatggc gcataaaggc ttggattggc tcatattgcc
    19801 attttgatat gaccttgtcc aagaatttct ttattgacat tctaataagt tctttcttcg
    19861 ccctgactag ttaaaatcac tggaccatcc tttgtaatca caaattgatg ctcatactgg
    19921 caggacaagc caccatcaag tgttttatgg gcccagcctg ttttcatatc tgtattaatt
    19981 tcccatgtgc cagtattgat catcggctct acggtgagca ccatgccctc cttcagacgt
    20041 agtcctcttc ctgctgtacc atagttaggc accatcggct cttcgtgcat ggttggtcca
    20101 acaccatgac caacaaggtc tcgaaccaca ccgtagccat gactttcagc atattgctgg
    20161 actgctgcac caatgtcacc aatgcggttc cccacaactg cctgctcgat cccacgatac
    20221 atggcttcct tggtcacgtc catcagcctt ttgacctcat cagacggtgt acctacagca
    20281 taagcccagc aggaatcagc caaaccacct gtataagatt ctgtccactt cttcatttct
    20341 gccacattat caaaatccaa ggccgctaca tcaacgacag ccttatcaag tggctcactt
    20401 agcaccatat ctaccttaag caaatcccct tcctgtagaa tataatggcg cggaaaagca
    20461 tgtgcaacct catcatttag cccgcagcag gtagcgtaag gataatccat taattggcca
    20521 tcaacaccga tctgtaaagg aagcacattg tcctccttgc agcgcctgcg cacatattct
    20581 tcgacctccc acatgtcaac cccaggctta atgatctgtc tgaggccaat gtgaatccca
    20641 gcaagaaagt ctcctgctct atccatagct tctatttcac gcgcagattt taatgttatc
    20701 attgtttttg tttctcctct aattaagctt agttgtaata atggctttag caatcacctg
    20761 atcatcaacc atgacctcca tatcaagtgt actgcttctt ctattttcag ttataatttt
    20821 agggtatatc ctcaattgat catcaatttg gacagcatgt agaaagtata tcatcatttg
    20881 ctcgataatg atattttttt ggtgtttttt cgttagcact ctgacactga tttcctttaa
    20941 gaattcagca accactccat ttgacagatt gccagcacta tcaatcatgg taggctcaat
    21001 catgacctga taataatcca aggtctcctc aaggcttgat agcatttgct ggctataggt
    21061 gtaaagattt cccggctggt gattcggcag gttttccata gcctgtcgtc tggtaataat
    21121 ccccagcaga aaatgatgat catcaactac tgggagcatg ttcaaatcct caaagatcat
    21181 tttttgacta atattagcca ggctagcatt gggctttgca gtgataggat ttggagacat
    21241 cacctgctca agtctagtct cagcaggctg atccaccaca tcacgcatac tgaccacacc
    21301 aaccacctga tcaagcgcat ctacaattgg aaaccttact tgacctgtct ttttaatcag
    21361 tgcattaaat tcctcgacag tgtctgtctc ataaaggcag ccgtattctt caactggaat
    21421 cagaacctga gcaactgttt ttaaatcagt cttaatgcga atattagaca aggcatggtt
    21481 aatcatcgtt gccactgtaa aggtatcgta atgtgtcacc ataaccggaa taccttggct
    21541 atcagctgtt tcaataacct gcttagacac cggaaagcca cccgtcacta agatagcatt
    21601 gtgattttta agggctaaca gttggatatt ttcacgatcg ccaacaatca aaagccctcc
    21661 tttgatcaaa taacggtgaa tattttgctg ggtcatcgct ccaatagaaa acttgctaaa
    21721 ctcatgtccc aaaccagcat gaccggctaa aacctcagaa tcactgatcc ttgcaatttc
    21781 ggcataggtc aaacggtcaa tacgaacccg tccttttttc tcaatgcgga cagtaccact
    21841 acgcggcttg gtctcaacaa tcccccgatt ttcagcctcc ttgatcgctc tataggcagt
    21901 accatcacta acctttaaat gatttgaaat acttcggacg ctcacacgct ttccaatagc
    21961 aagtctttct aaataatcta aaatgtcttg atgcttactc ataatgatac tcacctatcg
    22021 ttagttgata ttctaaataa tctcgtatgt gatgactatg ccgatcactg cccttaaatt
    22081 gctttgttaa tcgaaagccg gctttttcag caaccctctg gctggccttg ttttccagat
    22141 gtgtcacaat gatcagctgc ctcaagccaa actcctgaaa agctaaaaag gtaagcgtct
    22201 ttaagacctc ggtcattaag ccctgtcccc aaaagggctg cgctaaaaaa tagccaatct
    22261 cagcacttgc ctgctgctta tcatattttt ctagtctaat agagccaagc atgctatggc
    22321 tggtcttatc ctctattaac cagactccca agggctcttt cataaaagca ttgaccatta
    22381 agaaatcact ctcagccttg gtcatgctct ctggaaacac aaactggtaa tggctgttat
    22441 gactgatcat atcataaaac ggctgatgat ctgcatattg aaagggcctc aagagcagtc
    22501 gttgcgtctc aacaaaagca aaccttgcta gctgtgtcca aatatccata gcctcccctt
    22561 caacatgcct gtaatactat tattatagca gatatcacct aaacattcta taactgtcat
    22621 gagttttgcc atgatgatca taataacctg acaagccata tcatagctca atcagactct
    22681 aagctgttaa actattacta acagtcaaaa ccaaaaaaga gaagaccgtc tgatcttctc
    22741 ttgctatctt atctgctaat gcttaaatgg gctacatcat agaaaagtcc tatgagtaag
    22801 ctcatccttc taaggctaaa catgcttcca taaatacact gcttagtcct gctgacgctt
    22861 tgaagtcact gctaaagcac ctgcactcgc cataatggca agagccgctg ctgtaaagaa
    22921 tggattagcc ttctcaccag tcgttggaag agtcttagcc ttttgcttat ctttttgctt
    22981 agctggtgct gtcttagttg ctggtgtaag cggtgtcaac ggaagagaag ctgatggctt
    23041 ttctggatca gctggactct cctctaaagc ctcagtgact gtaaatgtct ttgtagcagc
    23101 gtcataagcc cattcaccag taacgccatt gtcattggca tattgcctga aggtctgctc
    23161 ggctgtggct gcgtctactg ccttggtagc tgtttcacct gagaaggtaa cccccttaat
    23221 aacaagccta taggtggtca aagctggtgt taattctgcc gcctcaatag tctcagctac
    23281 aggctgttca gtgactgtaa atgtctttgt ggcagcatca taagcccaaa cgccgtctac
    23341 accattttta ttagcatagt ctctgaaggt ctgctcagct acagctgcgt ctactgcctt
    23401 agtagctgtt tcacctgaaa aagttgctcc cttgatgaca agcttatagc tagtcaaggc
    23461 tggtgttagt tctgctgcgt caatgacctc agaactcggt agagctgata aaatctctgc
    23521 cttaagcgca ttgacacctt caacagtttt ggctttgttg attaaggtca catagtaatc
    23581 actaatgcca tactgcttta gttcattgat agcagcttct ttagcctcca acaaggctgc
    23641 tcctgtaatg tccgcaatag ctgtatgagc atcattaatg gctgcattca cttgatcaac
    23701 tgaagcagca tctgccacct tagctgctgc agcaactaga gctagctgaa ccttttgatc
    23761 gcttttgtgc tgatcactta aggcattgat tgttctgtaa gcctcacgtc ttgcttcatc
    23821 aagctgaaca ccagcaacag ctgcctttgc tttgtcaaga gctgctttag cctgatcaac
    23881 agtatctgca gcaagtgcct caactccagc attagcaaga acagcctgaa gctcttgatt
    23941 gtcagcgtag tcatcactca gctgattgat ttccctaaca gcttctctaa tgaaggctgt
    24001 tgtaggctct aacactgttg ctgcgtctaa agcacccact gaagtcgttc caaccagaaa
    24061 ggctgccgac actgaagcta aaccaacagc tgattgacgt aaaaagtagg ataccttttt
    24121 gtttttttcc atttttcctc cctcgctttt tgtaaaaaaa actttgacac taaaaacta
//
LOCUS       DARYNN010000032        23700 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.032, whole genome shotgun sequence.
ACCESSION   DARYNN010000032 DARYNN010000000
VERSION     DARYNN010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23700)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23700)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23700
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.032"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(<1..274)
                     /locus_tag="TVB59_001289"
     CDS             complement(<1..274)
                     /locus_tag="TVB59_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEL1010179.1"
                     /translation="MYKILVVDDDYEILKLMRTILEMKNYKVTTYQEVTFPINFRDFQ
                     GFDLILLDVMMPNVEGTQICQLIRDKVASPIIFVSAKDTEDDIIKGL"
     gene            complement(311..1687)
                     /locus_tag="TVB59_001290"
     CDS             complement(311..1687)
                     /locus_tag="TVB59_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEL1010180.1"
                     /translation="MLTMKHKMLIFCLLLSIFVSQFHMLHVYAETSSKTQYNILIKES
                     LDTNKVKKQLNDQGMIVLDEIPEINVLTIAAANDSSMILEKNCNYIDDISRNNTFTVN
                     PKMTYQFGHAFYLDSDLNYWNKQWDMQRSISTSSRFWHKSSGEVTIGVIDSGITDNNT
                     DISSKIISVQNFTEDPVTKAIDVNNVLDKTGHGTSVVGQMSSNGYYTGIAPGMKVRMY
                     KVFEEGNAQDEWILKAIIQAAKDDVDVINLSLGQYLLKASSNIDEDRTALINSYQRAI
                     NYAHKQGSVVVASVGDEGANLNNQAELKNLVSALTGRAFSSVDGTIEDIPAQLDNVVT
                     VGSVDGDGAISNFSNRGRNVVDIFAAGGGSKKLALHGYDTWINNKLFEQDWVIIPTLE
                     GKYTYGYGTSIAAPKVAAALGLIIEKYDLKDKPDEAITILYSNSWSSLDDNGKPIRLL
                     NITDFISK"
     gene            complement(1855..1986)
                     /locus_tag="TVB59_001291"
     CDS             complement(1855..1986)
                     /locus_tag="TVB59_001291"
                     /inference="COORDINATES: protein motif:HMM:NF022534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010181.1"
                     /translation="MEEETKLNQETMTTMIGKYECYARQLEKLAFVFNYKSELRTKD"
     gene            complement(3095..5041)
                     /gene="thrS"
                     /locus_tag="TVB59_001292"
     CDS             complement(3095..5041)
                     /gene="thrS"
                     /locus_tag="TVB59_001292"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEL1010182.1"
                     /translation="MITITFPDGAVREFESGVTTFEIADSISKSLAKKALAGKFNGQL
                     IDTTRAIEEDGSIEIITADHEDAFEVLRHSAAHLFAQAAKRLFPKLHLGVGPAIADGF
                     YYDTDNADGQISNEDLPRIEEEMKKIVKENFPCIREEITKEEALELFKDDPYKVELIN
                     EHADDAAGLTVYRQGEFVDLCRGPHVPSTGRIRVFHLLNVAGAYWRGNSDNNMMQRVY
                     GTAWFDKKDLKAYLTRLEEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRT
                     LERYITDKELASGYQHVYTPPLASVELYKTSGHWEHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVYKNHVHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSYRDPKDTHKYYDNDEMWENAQSMLKAA
                     LDEMGADYFEAEGEAAFYGPKLDIQVKTALGNEETLSTIQLDFLLPERFNLSYIGADG
                     EEHRPVMIHRGVISTMERFTAILIETYKGAFPTWLAPRQVTVIPISNEAHIDYAWEVA
                     KILRDHGIRADVDDRNEKMQYKIRASQTSKIPYQLIVGDKEMQDKSVNVRRYGSKATH
                     TEAISAFVDNILADIARKSRPAEG"
     gene            complement(5632..6966)
                     /locus_tag="TVB59_001293"
     CDS             complement(5632..6966)
                     /locus_tag="TVB59_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEL1010183.1"
                     /translation="MRVGLFTDTYFPQVSGVATSIRTLKEELEKEGHEVYIFTTTDKH
                     VKRFEDPTIIRLPSVPFVSFTDRRVVYRGLISSYKIAKEYHLDIIHTQTEFSLGLLGK
                     MVGKALRIPVVHTYHTQYEDYVSYIANGKIIRPSMVKPLLRGYLKDLDGVICPSRIVL
                     NLLEGYEVTIPKRVIPTGIALENYVREDIKKEDVAALRKELAISDDETMLLSLSRVSY
                     EKNIQAIIHQLPAVLSENSRIKLVIVGDGPYLQALKELAVSLGVEDHVVFTGMIAHDQ
                     VGLYYKACDFFISASTSETQGLTYIESLASGKPIIAHGNPYLDDLITDKMFGTLYYAE
                     SELSDAIIDAILETPQMNQRLLDEKRYEISAQHFGKSVYTFYLDTLISRHNKETKKLS
                     LYLNRTEKSGSIKLVQGAIHLPKRAAKATALTSVKVLKAPIKLVNAIRDFLD"
     gene            complement(6968..7966)
                     /locus_tag="TVB59_001294"
     CDS             complement(6968..7966)
                     /locus_tag="TVB59_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEL1010184.1"
                     /translation="MKVLLYLEAENYLRKSGIGRAIKHQAKALSLVGQEFTTDPKDDY
                     DLVHLNTYGLKSWLLMSKAQKAGKKVIMHGHSTEEDFRNSFIFSNLVSPLFKAYLCRF
                     YNKADAIITPTPYSKALIEHYGVKTPIFAVSNGIDLEQYGANADKEAAFRRYFNLKEG
                     EKVVMGAGLFFLRKGIDEFVKVAEMMPDVRFIWFGDTNKWVIPARVRQIVNGKHPDNV
                     IFPGYIKGDVYEGAMTGADAFFFPSREETEGIVVLEALASRQHLVLRDIPVYEGWIDQ
                     DSAELANDTSGFVAALRRILSGESNKTEAGYRVAEGRSLDRIAHQLVAIYQKVMEL"
     gene            complement(8262..9737)
                     /locus_tag="TVB59_001295"
     CDS             complement(8262..9737)
                     /locus_tag="TVB59_001295"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEL1010185.1"
                     /translation="MSHQLLMQAFEWYLPADGRHWQRLKSSIPELQQLGVSQLWLPPA
                     FKGTSSDDVGYGVYDLFDLGEFNQNGTVSTKYGSKEDYLQLIAALKEAKIKPIADVVL
                     NHKANGDHKERFSVIKMNPENRQQALTEPYEIEGWTGFDFPGRQNTYNDFKWHWYHFT
                     GLDYDAKANETGIYMITGDNKGWANDELIDDEHGNFDYLMYNDLDFKHPEVIQNLQDW
                     AKWFIETTGIEGFRLDAVKHIDSYFIQTFINDIRTQLKPDLEVFGEYWKSDQESMEDY
                     LEATKAQFALVDVALHMSFFNASQQGADFDLTTIFDGSLVASRPDLAITFVENHDTQR
                     GQALESTVEEWFKPLAYGLILLRQEGKPCLFYGDYYGISGDYPQQSFKEVITKMAELR
                     QQLVYGEQIDYFDHANCIGWTCLGDDQRPQPLAVVLSNGDAGWKHMEVGQAYAGQVFC
                     DFLDNCQETVVVAEDGWADFKVEAGSISAWVLQKAQPKEEA"
     gene            complement(9807..10808)
                     /gene="ccpA"
                     /locus_tag="TVB59_001296"
     CDS             complement(9807..10808)
                     /gene="ccpA"
                     /locus_tag="TVB59_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEL1010186.1"
                     /translation="MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFSILAKGIDDIAAMYKYNIVLASS
                     DEDDDKEVNVVNTLFAKQVDGIIFMGHHLTDKIRAEFSRSRTPIVLAGTVDLDHQLPS
                     VNIDYKAAVADVVDILAKDHQSIAFVSGPLIDDINGKVRLAGYKDGLKKNKLDFKEGL
                     VFEANYSYKEGFELAQRVINSGATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSN
                     DSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEILLNHGIKKRGTTK"
     gene            10982..12067
                     /locus_tag="TVB59_001297"
     CDS             10982..12067
                     /locus_tag="TVB59_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEL1010187.1"
                     /translation="MTKLDQIRLYLNQEKAELAIFSDSVTINYLTGFLCDPHERQMFL
                     FVYHDKAPVLFVPALEVARAEQLLDFPVFGYVDSENPWEKIKSILPSTAAKTIYAEFD
                     HLNITKFQGLQSVFSGRFDNLTPYIQRMRLIKSADEIQKMLIAGEFADKAVNVGFDNI
                     SLDVTETDIIAQIEFEMKKQGISKMSFETMVLTGNNAANPHGIPGTNKIENNALLLFD
                     LGVETLGYTSDMTRTVAVGKPDQFKLDIYQLCLEAQLTALDMIKPGVTAAQVDAAARQ
                     VIEKAGYGDYFNHRLGHGIGMDVHEFPSIMAGNDLILEEGMCFSVEPGIYIPGKVGVR
                     IEDCGHVTKDGFELFTQTPKELLYFEG"
     gene            complement(12241..13824)
                     /locus_tag="TVB59_001298"
     CDS             complement(12241..13824)
                     /locus_tag="TVB59_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011226359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1010188.1"
                     /translation="MKSILQVISKWQLCLYSLLALLYSLQGLLLSVLIQIAGQIDMNN
                     KGMVLLFGLGGVAFFVFIYMCMYLNNILARSMVRAFNCLIAKKALYHFYHKQLNYFTS
                     ALNSFLTQDIPMFWQEYLVPLFIYPVFGLSILASVLYLLLQDIYIGIAFTIGGFLMII
                     PQFVFNHLLQSRGLELSQAREKSLASITDFTKGADTIQSNQANEAFAHHVLEMIQHME
                     DKQYSYYTTHNLVMFWTGPLKGIGLVSPLIIGLLVMSYSSLSLTTLIAMITASTNLVS
                     PLQQLLEATSSLQSATAVKEKMVRVLALEEETKHQALTPTDDLTLDIYFKRLDKYFDH
                     RLIFQGIDGHISAGHKTLLTGASGSGKSTLFALLCGEDKDYSGTIYFEAANGKRYFPS
                     YDVVSLIHQKPYIFEGSLRDNLTLFQDYSDQRLKEILQQVHLWNELNGDLDLHLDGQN
                     LSGGQIMKLEIARCLLILKPILLADEVTAALDKESAREIRELLHSLPCTMVEIAHKYN
                     AQSYDCIYHLKDKELVRCS"
     gene            14062..14913
                     /locus_tag="TVB59_001299"
     CDS             14062..14913
                     /locus_tag="TVB59_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1010189.1"
                     /translation="MNIREKFKAIRKQRRLSLKTLGKIAGSATSISDFENGKTNLSND
                     VLLQLLGFMIVEINELFEWEDFHEKELVEAIKQIELAIKSKHIPALSQLQQDFQSLSK
                     TKEQYIYHIISLILTITIAEYQNKEIDPHIMSELTDYFFFLEYWTNLDVGLLGNIVHY
                     MTTDALILLTNDILEHTPQVLRNNLDRIRIDTVLNCLTVLINRKEEKASRTLLKLLFN
                     KHYPNYFAFEKLYLHELQAVYDFNWKDKEQALAAHHVILATISLLFTADEAKEWDSFF
                     QESTSSL"
     gene            15174..15842
                     /locus_tag="TVB59_001300"
     CDS             15174..15842
                     /locus_tag="TVB59_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEL1010190.1"
                     /translation="MSHKSIHQQLRNAFSFRTAVRVYNDQKIAKEDLDLILDAAWLSP
                     SSIGLEAWRFVVLENEAVKHELKEVSWGAVYQFETASHMILLISEKNARYDGASIKQS
                     LLRRGITDEQALASRLACYEAFQKHDMKIADDPRALFDWTAKQTYIALANMMTTAAFM
                     GIDSCPIEGFNYDKVNAILAKHGIINPDTEGISSMLSLGYRLRDPKHSQTRKPREEVI
                     SFFN"
     gene            15957..16883
                     /locus_tag="TVB59_001301"
     CDS             15957..16883
                     /locus_tag="TVB59_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEL1010191.1"
                     /translation="MTLLSVIIPCFNEEDTIIPYLEEMKQIEAAMTSQLAFEYLFIDD
                     GSTDQTLSVLRELAGRFSNVHYLSFSRHFGKEAGLLAGLEEAKGSYITVMDVDLQDPP
                     ELLPLMYSKLQEGFDVVATRRQSRQGEPAIRSFFARLFYRLVKHVSNTEIVDGVRDYR
                     LMTRQVVDSILELGEVNRFSKGIFSWVGYNTAYISFDNRKRQYGKTSWNFLELLNYSI
                     DGFINFSEMPLTIATWTGTLSFLLSLLAICFIVIRKLLFGDPVSGWASTVSIMLFIGG
                     IQLFCMGIIGKYISKIFLETKKRPVYIIKEKK"
     gene            complement(16867..17055)
                     /locus_tag="TVB59_001302"
     CDS             complement(16867..17055)
                     /locus_tag="TVB59_001302"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010192.1"
                     /translation="MTLSRLFRCEADARSHTKKDLMVLIGTIKSFCRACHDEGNQSLS
                     ASLAADRGLDDCSVISFL"
     gene            complement(17167..17634)
                     /gene="smpB"
                     /locus_tag="TVB59_001303"
     CDS             complement(17167..17634)
                     /gene="smpB"
                     /locus_tag="TVB59_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEL1010193.1"
                     /translation="MAKGEGNVLAQHKKARHDYHIVETVEAGIVLTGTEIKSVRAARI
                     QLKDGFAQIKNGEAWLVNVHIAPFEQGNIWNADPERTRKLLLKKREIQHLADELKGTG
                     MTLIPLKVYLKDGFAKVLIGLAKGKHDYDKRESIKRREQDRDIRRVMKSVNRR"
     gene            complement(17637..19961)
                     /gene="rnr"
                     /locus_tag="TVB59_001304"
     CDS             complement(17637..19961)
                     /gene="rnr"
                     /locus_tag="TVB59_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEL1010194.1"
                     /translation="MMIENITNYLKEHGQSNIHDLAAALEMTDARSFPRLIKAISKME
                     GKGLLSFSDEGEVFLRAPQQKKPEIRVQGIFRANKAGFGFLSVDDNEDDIFIGRDDVG
                     YASDGDRVEAVIKKPANRLKATAAEARVVAIVERSLKTVVGRVILDDDHPKYAGYIKS
                     KNQRIQQRIYIAKSPIALDGTEIIKADIVQYPKAGQDYFVGTVCDIIGHQHDVGIDVL
                     EVLESMDIVSAFPDDVLAEANAIPDAPSDQDLMGRVDLRKETTITIDGADAKDLDDAI
                     HIKRLANGNVELGVHIADVSYYVTEGSALDREAAARGTSVYVTDRVVPMLPERLSNGI
                     CSLNPKVDRLTQSAIMEIDHQGHVVDYQLCQSVINTTFRMTYSAVNQMIAGDSEALRE
                     FDRIADDVSTMVELHQILEAMRVKRGALNFDTQEARIIVNDKGMPVDVVLRQRGVAER
                     MIESFMLAANECVAEHFSRAGLPFIYRVHEEPKAEKLQTFIDYASAFGIQIQGTANKI
                     SQEALQAFMAKVEGSPGAEVLNMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRR
                     YPDLLVHRMIREYNQITQEKVDHFAQVIPELAVSSSQLERRAIDAERVVEAMKKAEYM
                     ADYIGDVFDGVIASVVKFGMFVELPNTIEGLVHITNLPEYYHYNERTLSLKGERSGKV
                     FRAGQPIRVRLVRADKETGDIDFDYLASDYDVVEKTTRSAKAKHKHRQKAASRASRSK
                     ESKPSKPKSKQKTRKKAKKPFYQKAAKKKGRKRS"
     gene            complement(20048..20284)
                     /gene="secG"
                     /locus_tag="TVB59_001305"
     CDS             complement(20048..20284)
                     /gene="secG"
                     /locus_tag="TVB59_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEL1010195.1"
                     /translation="MYDLLLTILLVLSVLLVIAIFMQPQKNPSSNVFDSSGSEALFER
                     TKARGFEAFMQRFTAVLVFFWLGIALVLAILSSK"
     gene            complement(20330..20476)
                     /gene="rpmG"
                     /locus_tag="TVB59_001306"
     CDS             complement(20330..20476)
                     /gene="rpmG"
                     /locus_tag="TVB59_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEL1010196.1"
                     /translation="MRVKIHLECSHCGSKNYLTSKNKTSHPEKIKVPKYCPKERKVTL
                     HVES"
     gene            20964..22796
                     /locus_tag="TVB59_001307"
     CDS             20964..22796
                     /locus_tag="TVB59_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL1010197.1"
                     /translation="MRKTMKKMLAASTLCIIMSGSFISGSARVLAEKYYGFNDGTGEH
                     SPFPVYVTPITKPNRNTAKVVYCFNKDMKWPETWDKAAPKKPDNLPLYYDMEGTDQLF
                     STYASGQLTPNVSKVLANIMAKGYPNNNEFAHHFKLTPNSAVKVTQIAVWTVTDNLKN
                     YSQYSLTREEEAALNYLTDKNGDDFSDSIKLKLYIPQNPRTIKYQNLLGYDLIVKTPE
                     KKDNCKCTKIYIEDNGKDGYYLYIYYDNNENNRYDSDKDSLLQKKYIKNGKDGKPGRP
                     GVPGLPGPAGPQGPRGDKGETGERGPKGEKGLDGKPGEKGPKGDTGKDGKDGQPGPQG
                     PKGDPGRDGKDGEPGKPGERGEKGPQGERGPQGLPGPKGEPGIPGPKDEDGKDGAPGH
                     DGQPGPKGEKGDPGQQGIPGPKGEPGRDGKDGEKGERGEQGPQGERGEQGPQGERGEQ
                     GPQGERGEQGPQGERGEQGPQGERGEQGPQGERGEQGPQGERGEQGPQGERGEQGPRG
                     ENPTPTPDPMPQPEPQPEPQPMPDPAPKPESKPEPKPIPQPEVKPQPETKPQQPNKPS
                     TITSQSSGKSLPKTNDTGSLITAFGTGLLTLLGLGFLAKRKRKQ"
     gene            23111..>23700
                     /locus_tag="TVB59_001308"
     CDS             23111..>23700
                     /locus_tag="TVB59_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL1010198.1"
                     /translation="MRKTMKKMLAASTVCIIMSGSFIGGSARILAEQYYGWNDGTRVK
                     SPFFLYVTPTNETTRKTGKNGTIVYCFNRDKEWPANWEEGRSLELVNAETAYKLPIYN
                     KLLGTTDSFTKNASKPRVSGDIGKALIAVLKNGYPNKNLSGLDDTKSRILTQLAIWYF
                     SDSYNKDYFKQNYELTDQENNSLMELIKVGEEAAQK"
BASE COUNT         7251 a         5436 c         4384 g         6629 t
ORIGIN      
        1 ttaatccttt aataatatcg tcttcagtat ctttagcact aacaaagata ataggagaag
       61 caactttatc tcggattaat tgacaaattt gtgtaccttc aacattaggc atcatgacat
      121 ctaataaaat caagtcaaac ccttgaaaat ctctaaaatt gattggaaaa gtcacttctt
      181 gataggttgt taccttgtaa tttttcatct caagaatggt ccgcataagt tttaaaatct
      241 cataatcatc atcaacaact agaatcttat acatagtctt acctcataat agttacactg
      301 ttattttaca ctattttgag ataaaatctg taatatttaa caatctaatt ggttttccat
      361 tatcatccaa gctactccaa gagttactat acaaaatagt tatggcctca tctggtttat
      421 cttttaaatc atatttttcg atgattaaac ctaaggcagc agctacttta ggggctgcaa
      481 tagaggtccc gtagccataa gtatatttcc cttctagtgt tgggataata acccaatctt
      541 gctcaaataa tttattgtta atccaagtgt catagccatg aagcgctagc ttcttgcttc
      601 ctccacctgc cgcaaagata tcaacgacat tccttccacg attggaaaag ttagatattg
      661 caccatcacc atcaacagat cctactgtca caacattatc tagctgtgcg ggaatatcct
      721 ctattgtccc atcgactgaa ctaaacgctc ttcctgtgag agcactgact aagttcttaa
      781 gctcagcttg attatttaag ttagctccct catcaccaac agaagcaact accactgagc
      841 cttgtttgtg tgcataattg attgcccgtt gatagctatt gattagagca gttctatctt
      901 catcaatatt tgatgaagcc tttaataaat actgaccaag actcaaattt atgacatcaa
      961 catcatcctt tgctgcttga ataattgctt ttaaaatcca ttcatcttga gcgtttccct
     1021 cttcaaacac cttatacatt ctaaccttca tgcctggagc aattcctgta taataaccat
     1081 ttgaagacat ttgtccaaca acagatgtac catgacctgt tttatccaaa acattattaa
     1141 catcaattgc cttagttact ggatcctccg taaaattttg aacagaaatg atctttgaag
     1201 aaatgtcagt attattatca gtaataccag aatctattac accaatggtt acctcacctg
     1261 atgacttatg ccaaaaccta ctactagtac taatacttct ttgcatatcc cattgtttat
     1321 tccagtaatt taaatcacta tctaaataaa atgcatgccc aaactgatat gtcattttgg
     1381 gatttactgt aaaagtatta ttccttgaaa tgtcatcaat atagttacaa ttcttttcca
     1441 aaatcataga tgagtcattt gcagcagcga ttgtcaaaac attaatttca ggaatttcat
     1501 caagcactat cattccctga tcatttaatt gcttttttac cttattggta tctaagcttt
     1561 cttttataag aatattatat tgagttttgc tactagtctc agcatagaca tgtaacatat
     1621 gaaattgaga tacaaaaata gacagtagca aacagaaaat caacatttta tgcttcatgg
     1681 tcagcactcc tttaagtatt gtttttacac ttatcgtatg actaacattt cagatttgtt
     1741 tcagattcta gaaaataata cttactattg tgcttattta agtccaaaaa ttagcattac
     1801 actcattaag tatctgagat taatctagct aacattctaa attgttttct cccactaatc
     1861 ttttgttctt aattccgact tataattaaa gacaaaagct aatttttcta actgcctcgc
     1921 atagcactca tacttgccaa tcattgttgt catcgtctcc tgattgagct tagtttcttc
     1981 ttccacctgc tccagtttac tagctgatat gcaagtgcaa tggtcgtttt ttgtgaatca
     2041 cacctacttt gaatctggta aaatcattct actaacaaac ttcctgtgta atttctagta
     2101 gcctaggtag cctgataaag agatttcttc aaataaaaat aaccatgtcg aatgccagcg
     2161 ctccatttct taccagcatt ttcattattc cccagctaaa gctctatcca tgaggctaag
     2221 tgacctgtgc ttagaattaa ctcatatcca cactagtctc agaaataaag actgaagcta
     2281 tcatgatgtc actactagga atgaatgaaa tctagggttt ctacttgaca gtcatagtga
     2341 gacaaacaag cggcaatttg ctcttctaaa ctcccgattt gtttctaata gcaagcataa
     2401 atctccatag actaccccca tagaaaatgg tggtgattgg agaaatcacc attaagtgct
     2461 tcacgacgtt gaggagcttt cttcttcaaa ctagtataaa caattaatgg actacttact
     2521 ctagctgtca taggcgtttg agcaatcagt agttgaaata gcttgcaacc gaaagcaccc
     2581 agcatactct caatgcggat cggaagttca atgccaccta actgtagaat tttataatgc
     2641 aaattgtcct ttattaagaa ccttattgat cattttaagc tttagttcgg gagaggaacg
     2701 aatctttttc cttagcagct ttacaatcaa ttaatcgtgc taaatacttt aaatggaatt
     2761 gattgatatc aaattgtttg aatgaataac tctggttttg taggccgcag atttctacct
     2821 tgtcttgatg tcttaatgtc atgttaaaag caccccattc gttagatagt ttgtctaact
     2881 tttggggcgc agttcattca ttagattttt tatctaattt ttgagaagca gtttacttct
     2941 gatgagggct tctatattgc tttcattagt tctatgagtg agagcaaagc tcttgtagct
     3001 atttgtccca gattttttta tgtcatctgt tttgcaagtc aagctgacgt ctgcttaatc
     3061 agcctatcta aaaccagctt gcttggtctg ctttttagcc ttcagctggg cgtgatttgc
     3121 gggcaatatc agccaaaatg ttatcaacaa atgctgaaat agcttcggta tgtgttgcct
     3181 tactgccata gcggcgcaca ttaactgact tgtcctgcat ctccttatca ccaacgatta
     3241 attggtaagg gattttactg gtttgagagg cacgaatctt atattgcatt ttctcattac
     3301 gatcatccac atctgcacga atcccatgat cacgaaggat tttagcaacc tcccaagcat
     3361 agtcaatatg ggcctcattg gaaattggga taactgttac ctgacgtggt gccagccatg
     3421 ttgggaaagc tcccttatag gtttcaatca aaatagcagt aaagcgctcc atggttgaaa
     3481 tcaccccgcg gtggatcatc accggacggt gttcttctcc atcagcacca atatagctca
     3541 gattaaaacg ctcaggcagt aagaagtcca gctgaatggt tgatagggtt tcttcatttc
     3601 caagggctgt tttgacctga atatcaagct ttggcccgta aaaggcagcc tctccttctg
     3661 cttcaaagta atcagcgccc atttcatcaa gcgcagcctt cagcatgctt tgagcatttt
     3721 cccacatctc atcgttatcg taatatttat gtgtatcctt tggatcacga taggacagac
     3781 ggaagcggta atctgttagg ttaaaatcct cataaacgtc aataatcagc tgaagagctc
     3841 gctggaattc ctcctgaatc tgctctggcg tcacaaacag gtgcccatcg tttaaggtca
     3901 tctcccgcac gcgctgaagc cctgaaagag cccctgattt ttcatagcgg tgcatcatac
     3961 caagctctgc aatacgaatc ggcagctcgc gataggaatg cacatggttt ttataaacct
     4021 gaatatggtg tgggcaattc attggacgaa ggacaaattc ttcaccatct cccatatcca
     4081 ttgtcgggaa catatcctcc tgataatgct cccagtggcc tgatgtttta taaagctcaa
     4141 ctgaagcaag cggcggagta taaacatgct gatagcctga tgccagctct ttatcagtga
     4201 tatagcgctc aagcgtgcga cgaatcgtcg ctccatttgg tagccaaaat ggcaagcctt
     4261 gtcctacctc ctgagagatc ataaacaaat caagctcctt gcctagctta cggtgatcgc
     4321 gctccttagc ctcctcaagg cgtgtcaaat aggccttgag gtccttttta tcaaaccagg
     4381 ctgtcccata gacacgctgc atcatgttat tatcgctatt gccacgccag taagctccag
     4441 ctacatttaa caaatgaaag acccgaatcc gacctgttga cggcacatga ggaccacgac
     4501 aaaggtccac aaattcaccc tgacggtaaa cagttaagcc agccgcatca tctgcatgct
     4561 cattaatcaa ctcaacctta taagggtcat ccttaaaaag ctcaagagcc tcttcttttg
     4621 tgatctcctc acgaatacat ggaaagttct ctttgacaat ttttttcatt tcctcttcaa
     4681 tgcgaggcag gtcttcgtta gagatttgac catcagcatt atctgtatca taataaaaac
     4741 catctgcaat ggcagggcct acaccaagat gcagcttggg gaacaagcgc ttagcagctt
     4801 gagcaaacaa gtgagccgca gaatgacgca gcacctcaaa agcgtcctca tgatcagcag
     4861 ttataatttc tatactaccg tcctcttcaa tggcgcgcgt ggtatcaatt aattgaccat
     4921 taaacttacc agccaaggcc tttttagcta gagatttgct gatagagtca gcaatctcaa
     4981 aggttgtgac accagattca aattcacgca ccgcgccgtc tgggaaagtg attgtaatca
     5041 tctgttttct cctataaacc atctagatac ttaaaacaag ctaatcaagc agggctatat
     5101 ctcccaagcc ttctgctgct acgacaaaat aaaaactgac tgcctcccaa aggacgcaat
     5161 cagcgtggtt ccacctttat ttatgcatga caaagaaatc ctgtcctgca cctcagcttg
     5221 gctatatcgt gaccaccgtt ttatgtttgc ataaaagcaa ggaaggagta ttacactaga
     5281 caccctgtgc tcttctcacc aaccagcact cgcttaaagg atgcgaccta atctaacttg
     5341 tcttcctgat tattatagca atatttggaa ataattcaag tgatttttcc taaaaaagct
     5401 gagataagcc cacagacctc caagcccaca aggcaagaat gactaggcaa ggaaccctga
     5461 aacttctgcc acaagccttt gaagaacagc tcaaacagga cttgccgcct gtcgtctcag
     5521 ttcacaagac aacaaactaa atcctttaga caaatgatta tcctaaagag ctatctgctc
     5581 tctcacgcag aaccaaagcc tgtaattgca ggcttctttg tttatttagc cttagtccaa
     5641 aaagtctcgg atcgcattga ccagcttgat aggggctttg agcaccttga cagatgtcag
     5701 tgcagttgcc ttagctgctc gcttaggcaa gtgaatcgct ccttgaacca gcttgattga
     5761 gccactcttt tctgttcgat tgagatagag acttagcttt ttcgtctctt tattgtgtcg
     5821 cgaaatcaag gtatctaaat aaaaggtgta cactgatttg ccaaaatgct gagctgaaat
     5881 ctcatagcgc ttctcatcta gcagcctctg gttcatttga ggtgtttcta aaatggcatc
     5941 aataatcgca tctgacaatt ctgactcagc ataataaagt gttccaaaca tcttatcggt
     6001 aatcaaatca tctaggtagg gattgccatg agcgatgatg ggcttgccac tagcaaggct
     6061 ctcaatataa gttagcccct gtgtctcact cgttgacgct gaaataaaga aatcacaggc
     6121 cttataataa agcccaacct gatcatgagc aatcatacca gtaaagacca catgatcctc
     6181 aacgcctaag ctgacagcca gctcctttaa ggcttgaaga taaggaccat caccaacaat
     6241 gacaagcttg atcctgctat tttcactcaa aacagctggc agctgatgga taatagcctg
     6301 aatattcttc tcataagaca cccgcgacag gctcaatagc atggtctcat catcagaaat
     6361 ggccaattcc tttctcaagg cagcgacatc ttctttttta atatcctcac gaacatagtt
     6421 ctctagtgca atgccagtcg gaatcacacg cttaggaatg gttacctcgt acccttccaa
     6481 aagatttagc acaatccgac ttgggcaaat aacaccatca aggtccttta aatacccacg
     6541 aagcaggggc ttgaccatgc taggtcgaat gatcttacca ttagcaatat agctcacata
     6601 atcctcatac tgggtatgat aggtgtgaac aaccggaatt cttaaggcct tgcccaccat
     6661 tttgcccaac aaacctaagc taaactctgt ttgagtatgg ataatgtcta aatgatattc
     6721 cttagcaatc ttgtaggagg aaatgagccc acgataaacc acacgacgat ccgtaaagga
     6781 cacaaaagga acacttggta accgaataat ggtcggatcc tcaaagcgct taacatgctt
     6841 gtctgttgtt gtgaaaatat agacctcatg cccctctttt tccagctcct cctttagggt
     6901 gcgaatactg gtagccactc cggaaacctg tggaaaatag gtatctgtaa atagacctac
     6961 acgcatctta taactccatt actttttgat aaatagccac taattgatga gcaatcctat
     7021 caaggctgcg cccctcggcg acacgatagc cggcctctgt tttgttgctt tcccctgaaa
     7081 gaatgcgtct taaggctgca acaaagcctg aggtatcatt tgccaactca gcactgtctt
     7141 gatcaatcca gccctcatag actggtatat cgcgtaaaac aagatgctgc cggctggcta
     7201 aggcttcgag aaccacaatg ccttctgttt cctcacgact tgggaagaaa aaggcgtcag
     7261 ccccagtcat agccccctca tacacatctc ccttgatata accagggaag atcacattat
     7321 cggggtgctt accgttgaca atctggcgga cacgagcagg aataacccat ttattggtat
     7381 caccaaacca gataaaccga acatctggca tcatctcagc aaccttaaca aactcatcaa
     7441 tcccttttct aagaaagaaa agccccgctc ccatgactac cttctcaccc tctttgaggt
     7501 taaaataacg ccgaaaggca gcttctttgt cagcattagc accatattgc tccaaatcaa
     7561 tcccattaga tactgcaaaa ataggagtct taaccccgta atgctcaatc aaggctttag
     7621 aataaggggt cggtgtgata atggcgtccg ccttattgta aaagcggcag agataggctt
     7681 tgaataaagg agacactaga tttgaaaaaa taaaggaatt tctaaaatcc tcctctgtcg
     7741 aatgcccatg catgatcacc tttttaccgg ccttttgagc ctttgacatc aaaagccagc
     7801 ttttaagccc ataggtattg agatgaacca aatcatagtc gtcctttgga tcagtggtga
     7861 actcctgtcc cacaagcgat agcgcttttg cctgatgctt aatcgctcgc ccgatacctg
     7921 attttcttaa ataattttct gcttctaaat acaataagac tttcatactg tctattatag
     7981 cctattttat ggtatttttc actaagagag ttaaaaatca gcccttagac tgattttagg
     8041 gtaaggcttc ttctacccct atactcatct caaaaatgct tttaagtcct gcttttgctg
     8101 tcatcaaatg gctgatcttg gtaatatcag ctagaccaag atcgtgaaag ctccagctca
     8161 aggctcacgt attagccctt tcaagaaagc ctcccacctt tctcactggc caaaaagcca
     8221 gcaagacctg gccttttctt ctgattaatt cagcctatca gctaagcttc ttcttttggc
     8281 tgtgcttttt gtaacaccca ggctgagata gagcctgcct ctaccttgaa atctgcccag
     8341 ccatcctcag caacaacaac agtctcctga caattgtcta agaaatcaca aaaaacttga
     8401 ccagcatagg cttgaccaac ctccatgtgc ttccagcctg catcgccatt agacaaaaca
     8461 actgccaaag gctgaggacg ctgatcatct cctaagcagg tccagccgat acaattggca
     8521 tgatcaaagt aatcaatctg ctccccatag accagctgct gcctgagctc tgccattttt
     8581 gtgataacct ccttaaaact ttgctgaggg tagtctccag aaataccata ataatcacca
     8641 taaaaaagac agggcttgcc ctcttgtcgt aaaagaatca ggccataggc taagggcttg
     8701 aaccattcct caacagttga ctctaaggct tgccctcttt gggtgtcatg gttttccaca
     8761 aaggtaatag caaggtctgg ccgactagcc acaagactgc catcaaaaat agtggtcaaa
     8821 tcaaaatcag ctccctgctg gctagcatta aaaaaggaca tgtgcagcgc aacatcaact
     8881 agagcaaact gagccttcgt tgcttcgagg taatcctcca tagattcctg atcagacttc
     8941 cagtattctc caaaaacctc taaatcgggc tttagctggg tacgaatatc attgataaag
     9001 gtctgaataa aataagaatc aatatgcttc acagcgtcta aacgaaagcc ctcaatacca
     9061 gttgtctcaa taaaccactt ggcccaatcc tgtaaatttt ggattacctc aggatgcttg
     9121 aaatctaagt cattgtacat tagataatca aaattaccat gctcatcgtc aatcagctca
     9181 tcattggccc agcccttgtt atcaccggtg atcatgtaaa tacctgtttc attagccttg
     9241 gcgtcataat ccaatcccgt aaaatggtac cagtgccatt taaagtcatt ataggtattt
     9301 tgtctgccgg gaaaatcaaa gcctgtccag ccttcaatct catagggctc tgtaagggcc
     9361 tgctgacggt tctctggatt cattttgatc acagaaaagc gttccttgtg atcaccatta
     9421 gccttgtggt tcagcacaac atcagcaata ggctttattt ttgcctcttt tagggctgca
     9481 atcagctgca aataatcctc tttgctgcca tattttgtgc tgacagttcc attttggtta
     9541 aactctccca aatcaaacaa atcgtaaaca ccgtacccca catcatcaga gctagtgccc
     9601 ttaaaggcag gcggcagcca cagctgacta acccctagct gttgtagctc aggaatactg
     9661 cttttcagcc tttgccaatg ccttccatcg gcaggcaaat accattcaaa ggcctgcatt
     9721 aatagttgat gactcatctt aacctcctaa aaaggacaaa ccagaaaact cctagtttgt
     9781 cctcaaaact gcctaaacag gcagaactat tttgttgtcc cacgcttttt aatgccatgg
     9841 ttcaataaaa tttctttttc ttctaattct tccttattca tgatcttagt gagcatacgc
     9901 atgctaacag cccccaagtc atagaccggc tggctgatag agctcaaatt tggacgtgtg
     9961 tactgaacga ctggagaatc attgcttgtg ataatctcaa agtcttctgg aacacgctta
    10021 ccagcttcaa aaagaccatt caaaaggcct gctgccagct cgtcctctgc aacataggca
    10081 gctgtcgctc cggaattgat cacacgctga gccagctcaa agccttcctt ataagaatag
    10141 ttggcctcaa acaccagacc ctctttaaag tcaagcttgt tcttcttgag tccgtccttg
    10201 tagccagcta aacgcacctt tccgttgata tcatcaatga gcggccctga aacaaaggca
    10261 atgctttggt ggtctttagc taaaatatcc accacatcag caacagccgc cttataatca
    10321 atgttaacac ttggcagctg atgatccaga tcaaccgttc ctgccagaac gattggcgta
    10381 cgcgaacgag aaaactctgc ccgaatcttg tcagtcaagt gatgtcccat gaaaataatg
    10441 ccatcgacct gctttgcaaa gagggtattc acaacattga cctctttatc atcgtcctca
    10501 tcacttgaag caagaacaat attgtacttg tacatagcag caatatcatc aattcccttt
    10561 gccagaatag aaaaatagct atttgcaata ttaggaatca caacaccgac tgttgttgtc
    10621 tttttacttg caagaccacg agcaacagca tttggacgat aatcgagacg atcaataacc
    10681 tctaagacct ttttgcgggt attttccttt acatttttgt taccatttac aactcgacta
    10741 actgtcgcca ttgaaactcc cgcttcgcga gcaacatcat aaatcgtgat tgtatcatct
    10801 gtattcattc ttcatcttcc tttctaactg aaaatgacgc tttcaaaaag tattttagca
    10861 tgatttgtaa ccactttcaa gtattaacgg ttgatttttg aaaaagtttt caaaaattca
    10921 taataagctt gcttttttaa gtattttttg gaaaaataga aggcagaaag aaggtttatc
    10981 tatgactaaa ttagatcaaa ttcgtttgta ccttaatcag gaaaaggctg agcttgctat
    11041 cttttctgat tctgtaacga tcaattactt aactggtttt ttatgtgatc ctcatgaaag
    11101 gcagatgttc ctatttgtct atcatgacaa ggctcctgtt ttgtttgtac cagctttaga
    11161 ggttgcaagg gctgaacaat tgctggactt ccctgttttt ggctacgttg actctgaaaa
    11221 tccttgggaa aaaatcaagt ctatcctacc aagcacagca gcaaagacca tttacgctga
    11281 gtttgatcat ttgaacatta ccaagtttca agggctgcag agtgtctttt caggacgctt
    11341 tgacaatcta accccttaca ttcaaagaat gcggctcatc aagtctgctg acgaaattca
    11401 aaaaatgctg attgctggag aatttgccga taaggctgtc aatgtgggct ttgataatat
    11461 ttcacttgac gtcaccgaga cagatatcat cgctcaaatc gaatttgaaa tgaaaaaaca
    11521 aggcatcagc aagatgagct ttgaaacgat ggttttaact ggtaacaacg ctgcaaaccc
    11581 acatggcatt ccaggaacca ataaaatcga aaacaatgcc ctgctgctct ttgaccttgg
    11641 tgttgaaaca ttaggctata ctagcgacat gacgcgtaca gttgccgttg gaaagccaga
    11701 ccaatttaag cttgatattt atcagctttg cttagaggct cagctaactg ctcttgatat
    11761 gattaagcca ggagtgactg cagctcaggt agatgccgct gctcgccaag tgattgaaaa
    11821 ggctggctat ggcgactact tcaatcacag gctcggccat ggtatcggta tggacgttca
    11881 cgaatttcca tcaatcatgg ctggcaatga cctgattctt gaagaaggca tgtgcttctc
    11941 agttgagcct ggtatctata tcccaggcaa ggttggggtt cgtattgagg actgtggtca
    12001 cgtaactaaa gacggctttg agctcttcac ccaaacacca aaagaattac tatactttga
    12061 agggtaatag gaggcttaaa aagcctgaaa caaaatgtct cagaccctaa tatctaaagc
    12121 aacagcactt ggtctgttac ttttcatatt acaggctatt ttctcacaag gaaaagtcaa
    12181 agcacccctt gatgggaaat cagaggggca aaagctattt gtactaagct caaaagctaa
    12241 tcaagagcac ctgaccagct ctttatcctt taagtgataa atgcaatcat aagactgtgc
    12301 attatattta tgagctatct caaccatggt gcaggggagt gaatggagta actcacgaat
    12361 ctctctggcg ctttctttgt ctagggcagc tgtgacctca tcagccagca aaatcggttt
    12421 tagtatcagc aagcagcgtg caatttccag cttcatgatt tgcccgccag agagattttg
    12481 cccatctaga tggagatcaa gatctccgtt tagctcattc caaagatgaa cctgctgtaa
    12541 tatctccttt agtcgctggt ccgaataatc ctgaaacagc gtgagattat ctcgcaagct
    12601 tccttcaaat atgtaaggct tttgatgtat caaagacaca acatcatagg aaggaaaata
    12661 gcgttttcca ttggcagctt caaaataaat agttccagaa taatccttat cctcaccaca
    12721 caaaagagca aataaagtag atttcccact accactggct cctgttagca aggttttgtg
    12781 ccctgctgaa atatgaccat ctatcccttg aaaaataagc ctatgatcaa aatacttatc
    12841 taacctctta aagtagatat caagtgtaag atcatctgta ggggttaagg cttgatgttt
    12901 tgtctcttcc tccagagcca atactctaac catcttctcc ttaacagcag ttgcagactg
    12961 taaactcgaa gtagcttcta ataattgctg caagggagag acaagattcg tagaagctgt
    13021 tatcatagca atgagagttg ttagtgatag acttgaatag ctcatcacca acagaccaat
    13081 aataagagga ctaaccaagc caatcccttt taatggacca gtccaaaaca ttaccagatt
    13141 gtgggtagta taatagctat attgcttgtc ttccatatgc tgaatcattt ctaacacatg
    13201 gtgagcaaaa gcttcgttgg cttgattact ctgtatcgtg tctgccccct tagtaaaatc
    13261 ggtgatactg gctaggcttt tctccctcgc ctgactaagc tctaagcctc gtgattgaag
    13321 taagtgattg aacacaaact gtggaataat catcaaaaag ccaccaatag taaaggcaat
    13381 accaatataa atatcctgca aaagaaggta caagacagag gctaagatag ataggccaaa
    13441 aacaggataa atgaataagg ggaccaaata ctcctgccaa aacataggaa tatcttgggt
    13501 caaaaacgaa tttaaggctg aagtaaaata gttgagctgt ttatgataaa aatgatataa
    13561 agccttcttt gcaataaggc aattaaacgc tctaaccata gaacgtgcta aaatgttatt
    13621 aagatacatg cacatataaa taaagacaaa aaaagctacg cctccaagac caaaaagcaa
    13681 taccattcct ttattgttca tatcaatttg ccctgctatc tgaattaata ctgataacaa
    13741 tagtccctgc aaggaataga gcaaagccaa taaactatac aagcaaagct gccattttga
    13801 aatgacttgt aaaatacttt tcatatcaat cactcctcac ctgaaaccta aatgtatcgc
    13861 tctcttggaa agtataaacg aaacatcctc atacaccaat catttccacc acaaactaga
    13921 ttcttgaatg ttaaatcaag ctcttgatca aaatcatgtt ctctgatttc ttgaacaacc
    13981 attggttctc tcctttcatt cttactattt ctagtatata atgggaaaaa atacgaaagg
    14041 aaaaatttcg gaaatccgga tatgaatatc agagagaaat ttaaagcaat tcgtaaacaa
    14101 agaagactat ccttaaaaac gcttggtaaa atagctggct cagccactag tatttctgac
    14161 ttcgaaaatg gaaaaacgaa cctttctaat gatgttttat tgcagctttt aggctttatg
    14221 attgttgaaa taaacgagct attcgaatgg gaggattttc acgaaaagga attggttgaa
    14281 gccatcaagc aaatcgaact ggcaataaaa tctaaacata ttcctgctct atctcagcta
    14341 cagcaggact ttcaaagctt atctaagaca aaggaacagt acatttacca catcatctca
    14401 ctgatcctaa ccatcaccat tgcagaatat caaaacaaag agatcgatcc acacatcatg
    14461 tctgagctaa cagactactt ctttttcttg gagtattgga ctaaccttga tgtcggccta
    14521 ctaggaaaca tcgtccacta catgacaaca gatgccctaa tcttattgac aaatgacatc
    14581 ttagagcata cgcctcaagt actccgaaat aacctagatc gtattaggat cgatactgta
    14641 ttaaactgtc ttactgtctt gattaatcgt aaagaggaga aggcaagcag aacacttctt
    14701 aaattattat ttaacaaaca ttatcctaat tactttgcct ttgaaaagct ctatttacat
    14761 gaattacaag cagtctatga ttttaactgg aaagataaag aacaggcgct tgcagctcat
    14821 cacgtcatac tggctaccat ttcattacta tttacagctg atgaagccaa agaatgggac
    14881 agcttctttc aagaaagtac tagctctttg taatactcca gctcatacac taaagaaaag
    14941 caaggataat cacataaaaa ctaatcacat cactttgccc tgctagctga attagcttgg
    15001 gtcatctctt atgcccagca aaacatcatc tagtctcagc tttcttccaa agcttcttgt
    15061 ctctctgggc ttgcaagctt ttgatagctt aagaggcaca agcattaaca aaggctaaca
    15121 aatgcctgta aaaatatgct atgatagggg taacaaaaac ctaggaggtg cttatgtcac
    15181 acaaatccat tcatcaacag cttagaaatg ctttttcctt tcggacagcg gtacgcgtct
    15241 acaatgacca aaaaatagcc aaagaagact tagacctgat tttagatgct gcctggctca
    15301 gtccttcctc tatcggcctt gaggcctggc ggtttgtcgt tttagaaaac gaagctgtca
    15361 agcatgagct aaaggaggtc tcttggggag cagtttatca gtttgagaca gctagtcata
    15421 tgatcctttt aatcagcgaa aaaaacgcca gatatgatgg cgcttctatc aagcaaagct
    15481 tattgcgcag aggcattact gacgagcaag ccttggccag tcgtctggca tgctacgaag
    15541 ccttccaaaa gcatgatatg aaaatagcag atgatcctcg ggctctcttt gactggactg
    15601 ccaagcaaac ctatatcgcg cttgctaata tgatgaccac tgctgctttt atggggattg
    15661 actcttgtcc gattgagggc tttaactatg acaaggtaaa tgctatctta gcaaaacatg
    15721 ggattatcaa ccctgatacc gagggtatct ctagcatgct gtctttaggc tatcgcctgc
    15781 gcgatcccaa acactcacaa accagaaagc ccagagaaga ggttatttcc ttctttaact
    15841 aagccccttt tgccattgct cccaaagaaa gtgcaaagac agtcctttgc cttttctttt
    15901 tcataactgt cgaattatgg tacaatgtgt caaaagacct atggaaagtg atgcctatga
    15961 cattattatc tgtaattatc ccctgcttca acgaagaaga cacgattatt ccttatcttg
    16021 aagaaatgaa gcaaatcgaa gcggccatga ccagccaatt agcctttgaa tatcttttta
    16081 ttgatgatgg ctctacagat caaaccctga gcgtgctaag agagcttgcg gggcgcttct
    16141 ctaatgtgca ttacctctcc ttttcacgac attttggcaa ggaagctgga ctattagccg
    16201 gcctagaaga ggcaaaagga agctatatta cggtgatgga cgttgacctc caggacccac
    16261 ccgagcttct cccgctgatg tatagcaaat tacaggaggg ctttgatgtg gttgccacaa
    16321 gaagacagag ccgacaagga gagcctgcta tccgttcctt ttttgctaga ctcttctaca
    16381 gattagtcaa gcatgtctcc aacaccgaaa tcgtcgatgg ggtacgtgat tatcgtttaa
    16441 tgacaagaca ggtggtggat agtattttag agttgggaga ggtcaatcgc ttttccaagg
    16501 ggattttttc ttgggttggc tacaatactg cctatatcag ctttgacaat cgtaagcggc
    16561 agtacggcaa aaccagctgg aactttcttg agcttttgaa ctactcgata gacggcttta
    16621 tcaatttttc tgagatgccc ttaaccattg ctacctggac tgggacactt agctttttgc
    16681 tatctctgct agccatttgc tttattgtta tacgcaagct gctttttggt gatccggttt
    16741 caggctgggc aagcactgta tccattatgc tatttatcgg tggaattcag ctgttttgca
    16801 tgggaatcat tggaaaatac atttccaaga tcttccttga aaccaagaaa agacccgtct
    16861 acatcatcaa agaaaagaaa taacagagca atcatcaagg cccctatcag ccgccaatga
    16921 ggccgataag gactggttgc cctcatcatg acaagcacga caaaaagact tgatggtccc
    16981 aatcaaaacc atcaagtctt ttttagtatg tgaccttgcg tctgcctcgc acctaaaaag
    17041 acgagataat gtcataacca ccgtctatct actgacccca aaaagttgga caatttagtt
    17101 ttaagcaagg gatttagttc tgtattgcac aggactaagc aaggccatca gcttgtaaac
    17161 agacgcttag cggcggttca cactcttcat cacacgccga atgtcacgat cctgctcgcg
    17221 tcgcttgatc gattcacgct tgtcataatc atgctttcct ttggcaaggc cgattaacac
    17281 cttggcaaag ccatccttaa gataaacctt tagaggaata agggtcattc ctgtgccctt
    17341 tagctcatct gctaggtgct gaatctcacg ctttttgagc aataatttgc gcgtgcgctc
    17401 cggatcagca ttccagatat ttccctgctc aaagggagca atatgaacat tgaccaacca
    17461 ggcctcacca ttcttgattt gggcaaagcc gtccttgagc tggatacgcg cggcacgaac
    17521 actcttaatc tccgtaccgg tcaacacaat tccagcctca actgtctcaa cgatatgata
    17581 gtcatgacga gcctttttgt gttgcgctaa tacattacct tcaccttttg ccatgcttaa
    17641 ctccttttac gacctttctt tttagcagct ttttggtaaa atggtttctt tgcttttttt
    17701 cttgtcttct gctttgattt tggctttgag ggcttggact ccttactcct gctagccctt
    17761 gaagcagcct tttgcctgtg cttatgctta gctttagctg accttgtggt cttttcaacc
    17821 acatcatagt cactagccaa gtaatcaaaa tcaatgtcac ctgtttcctt gtcagccctc
    17881 accaatctaa cccgaatcgg ctgacctgct ctaaatacct ttcctgagcg ttcacccttt
    17941 aaggagagtg tccgttcatt atagtgataa tattcaggca aattggtaat atgcaccaga
    18001 ccttcaattg tatttggcaa ttcgacaaac atgccaaact taaccacact agcaatcacg
    18061 ccatcaaaca catcaccaat ataatctgcc atgtattctg cttttttcat cgcctcaacc
    18121 acacgctccg cgtcaattgc acgacgctct agctgagatg acgatactgc caattctgga
    18181 ataacctgtg caaaatgatc caccttctcc tgcgtgatct gattgtattc tcgaatcatg
    18241 cggtgcacca gtaaatcagg gtaacgacga atcgggctgg taaaatgcgt gtagtagtct
    18301 gctgctaagc catagtgacc atgattatgc tcagaatacc tagcctgctg catagagcgc
    18361 agcagcatca tattcaaaac ctctgctcca ggacttcctt ctacctttgc cataaaggcc
    18421 tgcaaggctt cttgagaaat cttattagca gttccctgaa tctgaatccc aaaggcacta
    18481 gcgtaatcaa taaaggtctg caatttctct gcctttggct cctcatgaac ccggtaaata
    18541 aatggcaagc cagcccttga aaaatgctca gcaacacatt catttgccgc tagcataaag
    18601 gactcaatca tgcgctctgc aacacctcgc tggcgcaaga ccacatcaac cggcatgccc
    18661 ttatcattga caataatcct agcctcctgc gtgtcaaagt tcaaggcccc gcgcttcaca
    18721 cgcatcgcct ctaagatctg atgcagctca accatagtac tcacatcatc agcaattcta
    18781 tcaaattccc taagcgcctc actgtcacct gcaatcatct gattgaccgc gctgtaggtc
    18841 attctaaagg ttgtgttaat cactgactga cacagctgat aatcaaccac atgtccctga
    18901 tgatcaatct ccatgatcgc tgactgggtc aaccggtcaa cctttggatt gagagagcag
    18961 ataccatttg acaaccgctc cggcagcatt ggcaccacac gatctgtcac gtaaacagag
    19021 gtcccgcgcg cagctgcctc acgatccaag gctgaccctt ccgtcacata gtaggacaca
    19081 tctgcgatat gaaccccaag ctcaacgttt ccattggcca atctcttgat atggatggcg
    19141 tcatctaggt ctttagcatc agcaccatca atagtgatgg tcgtttcttt gcgcaaatca
    19201 acacgcccca taagatcctg atcactcgga gcatctggaa tggcattggc ctcagctaga
    19261 acgtcatctg gaaacgccga tacaatatcc atagattcca aaacctccag cacatcaatg
    19321 ccgacatcat gctgatgccc aataatatca cacacagtcc ctacaaaata atcctgccca
    19381 gccttagggt attgcacaat atcagcctta atgatttcag taccatctaa ggcaattgga
    19441 gattttgcga tataaatcct ctgttgaatc ctttgatttt tcgacttgat gtagccagca
    19501 tacttagggt gatcatcatc taaaataacc ctaccaacaa ccgtctttaa agagcgctcc
    19561 acgatagcta ccacgcgagc ctctgctgct gtagccttaa gccgattagc tggtttttta
    19621 ataacagcct caaccctatc gccatcacta gcatacccca catcatcacg accaataaaa
    19681 atgtcgtcct cattgtcatc aaccgacaaa aagccaaagc cagccttatt ggcacgaaaa
    19741 ataccttgaa cccttatctc tggctttttt tgctgtggtg ctctaagaaa cacctcaccc
    19801 tcatctgaaa aagacaaaag tcccttgcct tccattttgg aaatggcttt aatcaggcga
    19861 ggaaagctcc tcgcatcagt catctctagt gcagccgcca aatcatgaat atttgattgg
    19921 ccatgctcct ttaaataatt cgtaatgttc tctatcatca tacctatctt ctatttctaa
    19981 caccatactt gatggttgtg ctcattgata aaaaaatgag ctagactaac tctgtcaagc
    20041 tcactcctta tttacttgat aaaatggcaa gcactaacgc aattcctaac caaaaaaaca
    20101 ctagaactgc tgtaaaacgt tgcataaaag cttcaaatcc gcgagctttt gtacgctcaa
    20161 acaaggcttc tgagccactg ctatcaaaaa cattgctact aggatttttt tgtggctgca
    20221 taaagatagc aatcacaagc aacactgata atactagcaa tatcgtaagt agtaagtcgt
    20281 acatgttaat tcctccactg tagtctcaat cattctaaca caaaaccaac taagattcaa
    20341 catgcagcgt tacttttctc tccttaggac agtatttagg aaccttaatc ttctcagggt
    20401 gacttgtttt atttttacta gtcaaataat ttttgctgcc gcaatggctg cactccaaat
    20461 gaatctttac tctcacatca tttccctaat cttactatat tttatcagcg tcataaggct
    20521 tcaaatcacc cgcagcttct ttattaaaga tatctctagt tattatagca tattatccag
    20581 taagaaaaca aactcaggac ttttagcaaa aaaggcttaa gcgccaacca ataaacattc
    20641 caaggctatc ggggaatatt ttctaatggt tattataaat catgaacaat tacctaacaa
    20701 agcaactcca aaacaaagat aaaagacgaa cattcacctt gctgctcagc tatcaagata
    20761 aacaatcctg atagcatcaa ttttctttag gtcctcagca atcggttgta atatcagaca
    20821 attcaggtgt tgattaaaaa aaacgaaact acggagacca attgtcagaa agctattcac
    20881 agcccgcagg cgtcgtgcta aagtattgtc tggaaaaaga aaggtttagg aatgattata
    20941 cctaaactca aaggagagaa acaatgagaa aaacaatgaa gaagatgcta gcagcctcga
    21001 cgctctgcat catcatgtca ggcagcttca tcagcggctc agctagagtg ttggcggaga
    21061 agtattatgg ttttaatgat ggcacaggag agcattcacc attccctgta tacgttactc
    21121 caattactaa acctaatagg aatactgcca aagttgtcta ctgtttcaat aaagatatga
    21181 agtggccaga aacttgggat aaagcagcac caaaaaaacc agataattta cctctatact
    21241 acgatatgga aggtactgat caattattca gtacatatgc aagtggacaa cttactccta
    21301 atgtcagtaa agtcttagct aatataatgg ctaaaggtta tccaaacaac aatgagtttg
    21361 ctcaccattt taaactcact cccaattccg ctgtaaaagt tactcaaatc gcagtttgga
    21421 ctgttacgga taacctaaaa aactattctc aatacagtct aaccagagaa gaggaagctg
    21481 cattaaatta cctaactgac aaaaatgggg acgactttag cgatagtatc aagttaaaat
    21541 tatacattcc acaaaatcct cgaactataa aatatcaaaa tcttctaggt tatgacctaa
    21601 tagttaaaac tccagaaaaa aaagataatt gtaaatgcac caaaatttat atagaagata
    21661 atggaaaaga tggctattat ctgtatattt attatgacaa caatgaaaat aatagatatg
    21721 actcggacaa agatagccta ttgcaaaaga aatacataaa aaatgggaaa gatgggaaac
    21781 caggaagacc aggggttcca ggacttcctg gccctgctgg acctcaaggg cctagaggag
    21841 acaaaggaga aaccggggaa cgtggaccta aaggtgaaaa aggtctagac ggtaagcctg
    21901 gtgaaaaggg tcctaaaggc gatacaggaa aagatggtaa ggacggacaa cccggacctc
    21961 agggacctaa gggtgaccct ggacgtgatg gaaaagatgg cgaacctgga aaacctggcg
    22021 agcgcggtga gaaaggacct caaggcgaac gtggacctca aggacttcct gggcccaaag
    22081 gtgagcctgg aattccaggg cctaaggatg aagatggaaa agatggtgct cctggacatg
    22141 acggacaacc ggggcctaaa ggtgaaaaag gggaccctgg gcaacaaggc attccaggac
    22201 ctaaagggga acctggacgt gatggtaaag atggagaaaa aggcgagcgt ggagagcaag
    22261 gacctcaagg cgaacgtgga gagcaaggac ctcaaggcga acgtggagag caaggacctc
    22321 aaggcgaacg cggggagcaa ggacctcaag gcgaacgtgg ggagcaagga cctcaaggcg
    22381 aacgcggaga gcaaggacct caaggcgaac gcggagagca aggacctcaa ggcgaacgtg
    22441 gagagcaagg acctcaaggc gaacgtgggg agcaaggacc tcgtggagaa aatcctactc
    22501 ctaccccaga tccaatgcca caaccagaac cacaaccaga accacaacca atgcctgatc
    22561 cagcacctaa accagaatcc aagccagaac ctaagccgat acctcaacca gaggttaagc
    22621 ctcagccaga gacaaaacct caacaaccaa acaagccatc aaccattact agccaatcta
    22681 gcggcaaatc actgccaaaa acaaatgaca ctggcagctt gatcacagca tttggtacag
    22741 gcttactcac tcttcttgga ctaggcttcc tagcaaaacg caaaagaaag caataattaa
    22801 aacactaccc atagcctttt aatcattggc tatcaactag ataacaaaaa gcttatcgtt
    22861 ttactcctaa cgataggctt tttcgcattc cctattgctt ggtctcaata ctatttttcc
    22921 agctttaggc tggttttgct aatccaaaat aatatcagac aatttccgtt ttaattaaaa
    22981 aaaaaaaaaa aacgaaacta cggacgccaa ttgtcagaaa atggttcaca gcttagagtc
    23041 accatgttaa gctattctac gaagaagaaa ggtttaggaa tgactatttc taaactcaaa
    23101 ggagagaaac atgagaaaaa caatgaagaa gatgctggca gcctcgacag tctgcatcat
    23161 catgtcaggt agctttatcg gcggatcagc cagaatccta gccgagcagt attatgggtg
    23221 gaatgatgga acaagagtaa aatcaccttt tttcctttat gttacgccaa caaatgaaac
    23281 gactaggaaa accggaaaaa atggtacaat agtctattgt ttcaacagag ataaggaatg
    23341 gccagcaaat tgggaagaag gaagatcctt agaactagtg aatgctgaaa cagcttataa
    23401 attacccatc tataataaat tactaggtac aactgattcc tttactaaaa atgctagtaa
    23461 accaagagta tctggagata ttggtaaagc gctaatagct gtactgaaaa atggttatcc
    23521 taataaaaat ttatccggat tagatgacac taaaagtcga atactaactc aactagctat
    23581 ctggtatttc agtgatagtt ataataaaga ttattttaaa caaaattatg aattaactga
    23641 tcaagaaaat aactctctta tggagctgat taaagtcggt gaggaagcag ctcaaaaaca
//
LOCUS       DARYNN010000033        23505 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.033, whole genome shotgun sequence.
ACCESSION   DARYNN010000033 DARYNN010000000
VERSION     DARYNN010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23505)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23505)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23505
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.033"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(36..1367)
                     /locus_tag="TVB59_001309"
     CDS             complement(36..1367)
                     /locus_tag="TVB59_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HEL1010199.1"
                     /translation="MEFLGPIGVLLGIIAIVYFSLKEIHITIAAPMATILVVLLNSMP
                     LVESLLGKEPNNYMGALGGYIMSYFAIFLLGSILAKLMEVSGATVSIAEFILKKVGYQ
                     NPYRILVAIFIISAILTYGGISLFVVMFAVLPLARSLFKKMDLAWNLIQVPLWLGIAT
                     FTMTILPGTPAIQNVIPIQYLNTSLTAALVPSILGSVGCIAFGLFYMKRCLTKSLEVG
                     ENYATYTSQTNEDTTERVLPPFVVSILPLILLIVIAIIGSLLGDEFVKKNIIYVALLT
                     GIISAIVLFNKYIDKKIATLSIGASGAVGPIFATASAVAFGSVVTAASGFGVFSDIIL
                     NIPGPPVISLTVLTSAMAAITGSSSGALGIVMPNFAQYYLDAGVSPEIIHRVAAVASN
                     ILTIVPQSGVFLTFLSLTGLSHKNGFKQTFITVFGGTLVAESIIMLTSLFF"
     gene            complement(1458..2237)
                     /locus_tag="TVB59_001310"
     CDS             complement(1458..2237)
                     /locus_tag="TVB59_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyrate dehydrogenase"
                     /protein_id="HEL1010200.1"
                     /translation="MNMSKQVVFVTGAASGIGKQIGETFLKEGKIVVFSDINQEKLDA
                     VVDEYTTKGWAADSVLCDVTNEEAINKAIDYTVEKHGRLDILVNNAGLQHVAMIEDFP
                     TAKYEFMLKVMLTAPFIAIKRAFPTMKKQGFGRVINMASINGVIGFAGKAAYNSAKHG
                     LIGLTKVAALEAAELGITVNAICPGYVDTPLVRGQFEDLSKTRKIPLENVLEEVLYPL
                     VPQKRLIDVQEIADYVSFLASDKAKGITGQPVILDGGYTAQ"
     gene            complement(2268..2912)
                     /locus_tag="TVB59_001311"
     CDS             complement(2268..2912)
                     /locus_tag="TVB59_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HEL1010201.1"
                     /translation="MVKELSKEEIQERIAKRVALELPNNSLVNLGIGLPTKVARFLPE
                     GVTIMLQSENGFVGLDKVGDDIDPTIVNAGGQPVGIVPGGAFFDSTTSFGIIRGGHVD
                     ATVLGALQIDEKGNIANYLIPGKMVPGMGGAMDLLVGAKKVIVAMEHTNKGKWKILKE
                     CSLPLTAAGVVDKIVTEMGVFTVTPEGIAVEEIHPDYTFEEVQEATEARLIYHN"
     gene            complement(2918..3568)
                     /locus_tag="TVB59_001312"
     CDS             complement(2918..3568)
                     /locus_tag="TVB59_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HEL1010202.1"
                     /translation="MNKRISIEEAVNLVKDGDTIMVGGFMTNGSPERLIDALVAKGVT
                     NLTLICNDAGFPDKGVGKMVAQHRFRKIIASHIGLNKEAGRQMTAGETVIDLVPQGTL
                     AERIRAGAYGLGGFLTPTGIGTLVEEGKQKLQVNDKDYLLELPLKADVALIFADKADE
                     LGNLCYKGSENNFNQVMAANAKVTIVEAREIVSLGDIEPIAVQTPGIFVNYLVEGE"
     gene            complement(3583..4773)
                     /locus_tag="TVB59_001313"
     CDS             complement(3583..4773)
                     /locus_tag="TVB59_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HEL1010203.1"
                     /translation="MLVKEVVITTAVRTPIGSFGGAFKSVSAVQLGKVVVEALLEKSG
                     VKPEQIDEVIFGNVLHAGLGQNVARQVGITAGIPNDKPAFTVDMVCGSGLKSIELAAQ
                     SIVCGDSDIIIAGGTENMSQASYVLKDYRWGGRLGDGKIIDTMVNDGLTDAFHDYHMG
                     ITAENIAKNYGISRKAQDIFALASQEKAAAAQAAGRFVDEIIPVPVPQRKGDPILVAE
                     DEYIKAGTTLEKLTALCPAFVRDGSGTVTAGNASGINDGAAAVLLMSRDKAEELGLPI
                     LGAIKGYASAGVAPEVMGTGPIPSTQKALAKVGWTIEDLDLVEANEAFASQAISVVDE
                     LGLNAAIVNVNGGAIALGHPIGASGARILVTLLHEMEKRQAHKGLATLCIGGGQGTSV
                     LIEK"
     gene            4965..5867
                     /locus_tag="TVB59_001314"
     CDS             4965..5867
                     /locus_tag="TVB59_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEL1010204.1"
                     /translation="MDIKHLRFFIAIVENNFNLSRTAQQLYISQPTLSIMINDFEEKQ
                     GIKLFNKKYNKILGLTMTGKQFYEDSLEVIRKYDKMHQNLFSTNQKLDGNITIGIPPL
                     ILSIVFSKIMPEIILENPNIHFNIKEYGANRLRQELILENVDIAILLHPERIAANTID
                     SFQIQESELCAFVSKNHHLANKKILTWIELHNEKLAIFDKTFMIHHLIKEKCKYTDIN
                     PQIILESASWDFLINSTRINPQLMTIIPKPTVDSYGFQDIVAIPMENPIPWKVMVSRL
                     KKDHYSTIEEYIFNKMLEKFHVIE"
     gene            complement(6764..7906)
                     /locus_tag="TVB59_001315"
     CDS             complement(6764..7906)
                     /locus_tag="TVB59_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010205.1"
                     /translation="MKALLPFELKKLIRTKSVLGMFIVSLLAIFGLFYINFFNGQISG
                     SSIDKIHGRDAVEINKRFAEEHTGQLSNELLIRTIKDYTLGGSSKNPVFNVYGYYVTS
                     HFDPKFRDYYFNLKKEETIDFSKITPKSQTALGSYLPFKELKLGNFAPWNQLFLVINS
                     AYILLLLLSVYFIAPVFSGDTAKNMNPILLTTRYGRNKLTIAKIISSYLISTSVFVTF
                     YAIILAVFVWYFGLSGWDTSVQLNLYWINSNVNIMAFPEKMTLLGTFINLVTYQFIGL
                     ILITAITILISSKVKSPLTGFALSAASVFVPSFLMDIFQAGIPHKVLSILSVSTASTP
                     NIMLKLAYDGFFGSFWVDGLVIVMIRLAFAFLCLYLAYLSIKRVSQ"
     gene            complement(7903..8766)
                     /locus_tag="TVB59_001316"
     CDS             complement(7903..8766)
                     /locus_tag="TVB59_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1010206.1"
                     /translation="MLLELNQLSKSYGSKNILRRITTQFTPGLYGLLGANGTGKTTLL
                     NLISHFTTPDEGEILLDHKPQSEEFYQHIGFLPQQFSYYGRFSGRDFLLYMAALKGIP
                     KHKAKQETDELLKLVDLYDVRLKRIASYSGGMKQRLGIAQALLNDPKILILDEPTVGL
                     DPKERVKFRNIISELSANKIIILSTHIVSDVEAIAKEIIILKNGQFIHKSSSQELLKT
                     IFGKVWEFSVSDGSPLPRHGQYAVVNEKLVSSSRVFRVVSDEKPNQLAQLVSPTLEDL
                     YIYHFREEQVL"
     gene            complement(8777..9103)
                     /locus_tag="TVB59_001317"
     CDS             complement(8777..9103)
                     /locus_tag="TVB59_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator
                     DNA-binding domain-containing protein"
                     /protein_id="HEL1010207.1"
                     /translation="MKYVILYKNRSVVKLPISETYDVTTHSSKPHTVVFVTLKGEFGA
                     ATSLRQIEGESAGKLKRCHRQYFINESKISGFDYATRIIKVTDSRISYRRSLLSTELQ
                     VLSRLI"
     gene            complement(9707..9871)
                     /locus_tag="TVB59_001318"
     CDS             complement(9707..9871)
                     /locus_tag="TVB59_001318"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010208.1"
                     /translation="MDSMTVDAEKASQLDLGIENAGWFHFKLTTAIKLKQVEKVFLFT
                     AIFNRVDEFI"
     gene            complement(10110..11006)
                     /gene="era"
                     /locus_tag="TVB59_001319"
     CDS             complement(10110..11006)
                     /gene="era"
                     /locus_tag="TVB59_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEL1010209.1"
                     /translation="MFKSGFVAILGRPNVGKSTFLNHVMGQKIAVMSDKAQTTRNKIM
                     GIYTTETEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVETVLFMVPADEKRGKGDD
                     MIIERLKAARIPVILVINKIDKVHPDQLLEQIDDFRSQMDFKEIVPISALQGNNVETL
                     VQLLKDNLEEGFQYFPEDQITDHPERFLVSEMVREKVLHLTQQEVPHSVAVVVDSMKR
                     DEVTDKVHIRVTIMVERDSQKGIIIGKQGAMLKKIGKLARRDIELMLGDKVYLETWVK
                     VKKNWRDKKLDLADFGYNQKEY"
     gene            complement(11142..11543)
                     /locus_tag="TVB59_001320"
     CDS             complement(11142..11543)
                     /locus_tag="TVB59_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEL1010210.1"
                     /translation="MASQDNNKRKWKNRTVIASLEFALTGVLTAFKEERNLRSHLLSA
                     LLASLAGIVFGISAIEWLFLLLAIFLVITLEIVNSAIENVVDLASDYHFSMLAKHAKD
                     MAAGAVLVISGYAVLTGLIIFVPKIWRMLCH"
     gene            complement(11524..12021)
                     /gene="ybeY"
                     /locus_tag="TVB59_001321"
     CDS             complement(11524..12021)
                     /gene="ybeY"
                     /locus_tag="TVB59_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018167004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEL1010211.1"
                     /translation="MYIEMIDETKQVSQEMMEQTIDLLNFAAKTIGKEDKEMAVTFVT
                     NDRSHALNLEYRDTDRPTDVISLEYKPELPIAFSQEDLELDPDLAGMIQEFDAYIGEL
                     FISVDKAHEQAEAYGHSFEREMGFLAVHGFLHINGYDHYTPEEEKEMFTLQEEILTAY
                     GLTRQ"
     gene            complement(12370..12996)
                     /locus_tag="TVB59_001322"
     CDS             complement(12370..12996)
                     /locus_tag="TVB59_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1010212.1"
                     /translation="MASFFEKLAEHRYLETERLCLRPVTLDDAKAMFDYASDEETVRY
                     SFPANQTIEETRQVIASVYLASPLGRWGIVLKETGDFIGTLDLHHIQLDLGRAEIGYC
                     LHKHHWGRGYATEAVKAVLVLCFEALGMNCVIAKHDKANPALGRVMAKSGMCFSHEEP
                     YAKRDHLDSNRFVTVLHYYLTKEDYDKQKSLASANKPDRYLHNSFESS"
     gene            complement(13051..13626)
                     /locus_tag="TVB59_001323"
     CDS             complement(13051..13626)
                     /locus_tag="TVB59_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEL1010213.1"
                     /translation="MTELLQAIMADPANRDYTKKGIEPLYAAPQTARIVIVGQAPGIV
                     AQETRLYWNDRSGVRLRAWLGVDDRTFYQSGLFGVLPMDFYYPGKGKSGDLPPRKGFA
                     AKWHGPLMALMPQVELVVLVGQYAQQYYLGEGCRRNLTETVQHFEDYLPDYFPLVHPS
                     PRNQLWLAKNAWFEEELVPVLKDKVRQILRG"
     gene            complement(13673..14773)
                     /locus_tag="TVB59_001324"
     CDS             complement(13673..14773)
                     /locus_tag="TVB59_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEL1010214.1"
                     /translation="MHYSTDISLNHPDDLLALFGSNERHLKMIESHLNVVIHARTERV
                     QIIGDDERAVELARLTIQALLVLVGRGMVINTSDVVTALSMADSDRLDQFVALYEEEI
                     IKDFYSKPIRVKTLGQKAYVDSIKHHDVVFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKEQTTRLMERDIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFQSKMIVNGDISQIDLPRHITSG
                     LIDAAQKLQAIKQIDFVHFSAKDVVRHPVVAEIIKAYETVGSKAESLKSSPNQLQHQT
                     KAPDRPKTETGQSTSGLTTYEVIGELPKEDKS"
     gene            complement(14876..15091)
                     /locus_tag="TVB59_001325"
     CDS             complement(14876..15091)
                     /locus_tag="TVB59_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEL1010215.1"
                     /translation="MRKAFYTWLMAQRNSTSNKPAALLADLVFEDPTFPKHTDDFETI
                     SRYLEEEASFSFNLGQFDQIWEDYLSH"
     gene            complement(15088..15597)
                     /gene="msrA"
                     /locus_tag="TVB59_001326"
     CDS             complement(15088..15597)
                     /gene="msrA"
                     /locus_tag="TVB59_001326"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HEL1010216.1"
                     /translation="MERAIFAGGCFWCMVQPFEEQAGILSVRSGYTGGHVHNPSYEQV
                     CSKTTGHTEAVEIIFDPSLISYSDLVELYWAQTDPTDAFGQFEDRGDNYRPVIYYTDE
                     RQREIAERSKQTLQASGRFDQPIVTSIEPAEPFYLAEDYHQGFYQKNPERYAQSSAIR
                     HQFLEEHWQ"
     gene            complement(15935..16792)
                     /gene="cvfB"
                     /locus_tag="TVB59_001327"
     CDS             complement(15935..16792)
                     /gene="cvfB"
                     /locus_tag="TVB59_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEL1010217.1"
                     /translation="MNHLLATVITGLVKEENSQFYLVQKEGLSFALAKEEGSHRLGDM
                     VKGFVYTDMKQRLRLTTKPIDARRDHYGWGEVTTVRRDLGVFVDTGIPDKEIVVSLDV
                     LPELKDLWPKKGDRLYLKLVVDKKDRIWGLPAEPEIFQRLASPAYDNMQNQSLPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYTEPRLGQVLTARVIGFRERDRTLNLSLKPRSF
                     EMLENDAQMILTYLKSNGGYMTLNDKSSPEDIKATFGISKGQFKKALGGLMKANKIKQ
                     DVTGTELIS"
     gene            complement(16926..17483)
                     /gene="frr"
                     /locus_tag="TVB59_001328"
     CDS             complement(16926..17483)
                     /gene="frr"
                     /locus_tag="TVB59_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEL1010218.1"
                     /translation="MANAIIETAKERFTQSHHSLAREYASIRAGRANASLLDRIQVDY
                     YGAPTPLNQLASITVPEARVLLISPFDKSSIKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRKELAKEVKKVGETAKVSIRNIRRDAMDEAKKQEKAKEITEDELKALEKDI
                     QKATDEAVKEIDRMTADKEKELLSV"
     gene            complement(17520..18248)
                     /locus_tag="TVB59_001329"
     CDS             complement(17520..18248)
                     /locus_tag="TVB59_001329"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEL1010219.1"
                     /translation="MKPKYQRILIKLSGEALAGDKGVGIDITTVQSIAKEIAEVHNSG
                     VEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQHYGVDTRVQT
                     AIPMQNVAEPYIRGRALRHLEKGRIVVFGAGIGSPYFSTDTTAALRAAEIEADAILMA
                     KNGVDGVYNADPRKDANAVKFDELTHGEVIKRGLKIMDATASTLSMDNDIDLVVFNMN
                     EAGNIKRVVFGEHIGTTVSNKACD"
     gene            complement(18547..19227)
                     /locus_tag="TVB59_001330"
     CDS             complement(18547..19227)
                     /locus_tag="TVB59_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1010220.1"
                     /translation="MIEFRHVYKSFHQKPVLTDCHFQMEKGESLGIMGESGSGKTTLA
                     RLIIGLEQPTAGQVLFHGQPYSVKVCGPRILLVFQDALRSVNPLFTIQEILTEALSKD
                     FALEEVVQILAAVGLDATHLGKKARELSGGQLQRVCIARALLLRPEVIIFDEALSGLD
                     PITQGQLLDLLYELKQEYQLTYIFIAHDANICQAICHRVLLLEQGRLVAVRDKEPQTS
                     CGGIGLDN"
     gene            complement(19214..20002)
                     /locus_tag="TVB59_001331"
     CDS             complement(19214..20002)
                     /locus_tag="TVB59_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1010221.1"
                     /translation="MERLIVNDLSAYNGSDVLLSKLNLELPLGSSLVIVGRSGSGKTL
                     LTKLLIGQCPSNVQMTGRITCQDMRLDQLDAKQWQSIRGRHMAYMVQNPMAMFNPFQT
                     IEAHLLETIRSHERLSKRACLKRALPFMRELYLEQPEELLRKYPFELSGGMLQRVMLA
                     ILLCLDPQIIILDEPTSALDDANRSNIIRMLKLLQDKGKTIITVTHDYQLAQTLGGQL
                     LVMSKGKIIEQGSVESIFHRPSQAATKELLLQNHYDRLIRYDRV"
     gene            complement(19990..20796)
                     /locus_tag="TVB59_001332"
     CDS             complement(19990..20796)
                     /locus_tag="TVB59_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1010222.1"
                     /translation="MPKYVIGSAVMLLLLFICVLFAPYLAPFDPHAVDVASKLMPPSQ
                     QHLLGTDQLGRDVLSRLLYGAKYSLLLAVTISLLELSIGAVVGLVVGWYQGRLEAAFL
                     WLADVVSAFPSFLLSLATMGILGQGIGNMILAIVLVEWLYYARLMVTMVKSAKAEPYV
                     ISAQTMGLSVRHILKKHILPFVYRPIVVLALMNIGNIILMISSFSFLGIGVQPNVTEW
                     GMMLHDARSYFRTALWLMMSPGLAILVTVLAFNSLGDYADAKGWRKTWNG"
     gene            complement(20781..21722)
                     /locus_tag="TVB59_001333"
     CDS             complement(20781..21722)
                     /locus_tag="TVB59_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1010223.1"
                     /translation="MMKKLISTFGALLMISIVTFVLVKLSSANPAEQYLRLSKISITP
                     EALHNARLYLGLDKPLWEQYVTWLSDILVGNFGTSYVLKVPVLPLVVERFLATLMLSL
                     TSFLLVLVIAFPLGVGSGLFEHSLFDRLVRLFSFVAVSMPSFWLGYLLIIAFSVKLNL
                     LPVSGKAGASSLILPSITLSFSLIGQYTALIRKAISEQLTSLHVENARLRGVKTYYIV
                     KHHLIRNAFPAIATGLSLTFVYLMTGSIIVEDIFSWNGIGSLFVMSLKAADIPVIQAC
                     MLLFGALFLLHHVITQELVSFIDPRLRKTKEEACPNT"
     gene            complement(21800..23422)
                     /gene="nikA"
                     /locus_tag="TVB59_001334"
     CDS             complement(21800..23422)
                     /gene="nikA"
                     /locus_tag="TVB59_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel ABC transporter, nickel/metallophore
                     periplasmic binding protein"
                     /protein_id="HEL1010224.1"
                     /translation="MKTKLNVLLLFFFALLLTACQNAKQASYRTDQLRIAWGEDFGDV
                     NPHRYNPDQFVIQDMVYEGLVRYGDKGNIEPALAESWTISPDGKTYTFNLRQAKFSDG
                     SDFNAQNVKRNFDSIFSEQNKGNHNWFHFTNQLDSYKALDDHTFEIKLKEAYSATLYD
                     LSMIRPIRFLADAGFPDGDDTNKHNVKKPIGTGQWVVKEKKANEYITFTRHESYWGEK
                     PKLKEVTIKIMPDAETRALAFEAGDIDLIYGNGLISLDTFVQYAKDKKYVTDVSQPMS
                     TRLLLLNAKQSVFQDKRVRQAMNHAVDKKAIAKHTFRGTETAADTIFSKTTPHADAGL
                     VPYEYNLQKAKDMLTAAGWKENQEGIREKDGQQLRLQVPYISTKATDKDLVEYFQGEW
                     KKLGIDVVLTAMEEDDYWANAKTGQFDMMLTYSWGAPWDPHAWMTALTAKADHGHPEN
                     IALESLPSKAEIDRLIKSVLIEPDGDKVDKGYKQVLSLLHDEAVYIPLTYQSVVSVYR
                     KGDFKTMRFAPEENALPLRYIEKSAADKAVKN"
BASE COUNT         7193 a         5581 c         4126 g         6605 t
ORIGIN      
        1 aatagaccaa tggttttcca ttgatctact gtgtattaaa aaaacaggct agttaacata
       61 ataatgctct cggccaccaa cgtaccacca aaaactgtaa taaaggtttg tttaaagcca
      121 tttttatggc tgagaccagt aaggctcaag aaggttaaaa agacgccaga ctggggtaca
      181 atggtcaaaa tattagaggc aacagctgcc acacgatgaa tgatctcagg tgaaacgcct
      241 gcatctaaat aatattgagc aaaatttggc attacgatcc ctaacgctcc tgaagacgaa
      301 cctgtaatag ctgccatagc cgaagtcagg acagtcaagc tgatcacagg tggcccagga
      361 atattcaaaa tgatgtctga gaatacgcca aaaccagatg ctgctgtaac aacagaacca
      421 aaggctactg cagaggctgt cgcaaagatt ggaccaaccg caccgctagc accaatgctg
      481 agggtcgcaa ttttcttatc aatgtacttg ttaaataaaa cgatagctga aataattcct
      541 gtcaagaggg ccacataaat gatatttttc ttaacgaatt cgtcccctag cagactacct
      601 atgatggcaa taacaatcaa gagtatcaaa ggcaagatgc tgactacaaa tggtggtaaa
      661 accctttcag ttgtatcttc atttgtttga ctagtatagg tcgcatagtt ttcgccaact
      721 tctaaactct tagtcaaaca acgcttcata tagaaaagac caaaggcgat acagccaaca
      781 ctccctaaaa tacttggcac caaggctgcg gttagagacg tgttaagata ttgtataggg
      841 ataacgtttt gaatcgctgg tgtaccaggt aagatcgtca tagtaaaggt tgcaatcccc
      901 aaccaaagtg gtacttgaat taagttccat gctaagtcca tctttttaaa gagagagcgt
      961 gccaagggta gaacagcaaa catgaccaca aagagactaa taccaccata agtcaaaata
     1021 gcactgatga taaaaatagc caccaagata cggtaagggt tttgataacc tacttttttc
     1081 aagataaatt cagcaatgga aactgttgca ccactgactt ccatcaattt agctaaaata
     1141 gaccccaaca agaagatagc aaagtagctc atgatatagc cacccagcgc acccatatag
     1201 ttatttggtt ccttacccaa gagtgactca actagtggca tactatttag aaggacgacc
     1261 aaaatcgttg ccataggagc cgcaatggta atatgaattt cctttagaga aaaataaacg
     1321 atggcaataa tgcccagcaa gaccccaatt ggtcctaaaa attccatagt gtttctcctc
     1381 tcacattcag aaggagcaag agatagagaa atgtcactct atctccaatc ctcttattta
     1441 cactgaacgg acagctctta ctgagcagtg tagccaccat ccaagataac cggttgtcca
     1501 gtaattccct ttgccttatc acttgctagg aaggagacat aatctgcaat ttcttgtacg
     1561 tcaatcaaac gtttttgcgg taccaacggg tacaacactt cttccaatac attttcaagc
     1621 ggaatcttac gtgtcttaga gaggtcttca aattggccac gaacgagtgg tgtgtccaca
     1681 tagcctggac agatagcgtt gactgtgata cctaattctg cggcttcaag cgctgcaacc
     1741 tttgtcaagc caatcaaacc gtgttttgct gaattgtaag ccgcttttcc ggcaaaacca
     1801 atgacaccat tgatagaagc catattaatg acacgaccaa agccttgctt tttcatagtt
     1861 ggaaaagcgc gcttaatagc gataaatggc gctgtcaaca tgaccttcaa cataaattca
     1921 tattttgctg ttggaaaatc ttcaatcatg gcaacatgct gcaaacctgc gttgttgacc
     1981 aaaatatcca aacgaccatg cttttcaact gtataatcaa tcgctttatt gatcgcttct
     2041 tcatttgtca catcacacaa aacagaatca gccgcccagc cttttgtggt atactcatca
     2101 acaacagcat ctaatttttc ttgattgata tctgaaaaga caacgatttt gccctctttt
     2161 aagaatgttt caccaatttg tttaccaata ccgcttgctg cacctgttac gaatactact
     2221 tgtttagaca tatttatttc ctcacttttt ttaaatattg ttttctatca gttatgataa
     2281 attaatcttg cttcggtggc ttcttgaact tcttcaaagg tataatctgg atgaatttct
     2341 tctactgcga ttccctctgg agtgactgtg aagacaccca tttctgtgac aatcttgtca
     2401 acaactcctg ctgctgtcaa tggcaatgaa cactccttca agattttcca tttgccttta
     2461 ttggtatgct ccatagcaac aatgactttt ttagcaccga ctagtaaatc catggcaccg
     2521 cccattcctg gaaccatttt ccctggaata agatagtttg cgatgtttcc tttttcatca
     2581 atttgcaaag cgccaagaac tgttgcatcg acgtggccac cacgaatgat cccaaatgaa
     2641 gtggtgctat caaaaaatgc tccgcctggt acgatgccaa ccggctgacc acctgcatta
     2701 actatagttg gatcaatgtc atcgcctact ttatctaagc cgacaaaacc attctcagac
     2761 tgcagcatga tagtcacacc ttctggtaaa aatctagcta ccttggttgg caagccaatc
     2821 cccaaattga ccagggaatt atttggaagc tcgagtgcca cacgtttagc aattcgttct
     2881 tgaatttctt ctttgcttaa ttctttcacc ataacgctca ttctccttcc actagataat
     2941 tgacaaatat gcctggtgtt tgaactgcaa tgggttcaat gtctccaagc gagacaattt
     3001 cacgcgcttc aacgatggtc acttttgcat ttgctgccat aacctggttg aaattatttt
     3061 cagagccctt gtagcatagg tttcctaatt catcagcctt atctgcaaaa attaaagcga
     3121 cgtcagcttt caatggtaat tctaacagat aatccttgtc attgacctgt aatttttgct
     3181 taccttcctc taccaaggta ccgatgcctg tcggagtcaa gaagccaccc agtccgtaag
     3241 ctcctgctcg gattctttca gccaaggttc cttgtggcac taagtcaatc actgtttcac
     3301 cggctgtcat ttggcggcct gcttctttgt tcaagccaat atgagaagcg ataattttcc
     3361 gaaaccgatg ttgtgctacc attttaccga cacccttgtc tgggaagcct gcatcgttac
     3421 aaataagagt taaatttgta actccttttg ctaccaaagc gtcaatcagg cgctctggac
     3481 tcccgttagt cataaaacca ccaaccatga tggtgtcgcc atcctttaca aggttaacag
     3541 cttcttctat gctaattcgt ttattcatga aaccatctcc ttttattttt caatcaatac
     3601 agacgtccct tgaccgccac cgatacagag tgttgccaat cctttatgtg cctgacgctt
     3661 ttccatctcg tgcaatagtg tgaccaagat acgcgcaccg ctagcaccga tcggatgacc
     3721 aagagcaata gcaccaccat tgacattgac gatagccgca ttaagaccaa gctcatctac
     3781 aacactgata gcttgtgagg caaaggcttc attggcctcc accaaatcca agtcttcaat
     3841 tgtccaacca accttagcaa gggccttctg agtggaagga attggcccag tacccatgac
     3901 ctctggtgct acaccagcac ttgcataacc tttaatggct cccagaattg gaagaccaag
     3961 ttcttcagct ttgtcacgac tcatgagaag gacagctgcc gcaccgtcat taattcctga
     4021 agcgtttcct gcagtaacag ttcctgaacc atctcggaca aaggccggac aaagggctgt
     4081 taatttttca agggttgttc cagctttaat gtactcatct tctgccacca aaattggatc
     4141 acctttacgt tgcggtactg gcactggaat aatctcatct acaaagcgac cagcggcctg
     4201 cgcagcagca gctttttcct gactagccaa agcaaatata tcttgagctt tacggctaat
     4261 cccatagttt tttgcgatat tttctgctgt aattcccatg tggtaatcat gaaaggcatc
     4321 tgtcaaacca tcattgacca tagtatcaat gatttttcca tcgcctaagc gaccacccca
     4381 acggtaatct ttgagcacat agctggcttg gctcatattt tctgtcccac ctgcaataat
     4441 gatatctgaa tcaccacaga cgatactttg tgctgctaac tcgatggatt tgagaccaga
     4501 accacagacc atatccacag tgaaggcagg tttgtcgttt ggaatacctg cagttatccc
     4561 tacctgtcta gcaacatttt gaccgagtcc tgcatggagg acatttccga aaatgacctc
     4621 gtcaatttgt tcaggcttca cacctgattt ctctagtaat gcttctacaa ccacttttcc
     4681 taattgaaca gccgagacag atttaaaggc tccaccaaat gaaccaatgg gtgtcctaac
     4741 agctgtagtg ataacaactt ctttaaccaa catgcgattc tccaatctat ttgttataga
     4801 aagcgctttc tgtttttgtg aatttatttt atcactacta aaagcgtttg caaaattcga
     4861 tttttttata tgactataaa aaatttttat tattttttat tgacagctat aaaaattatt
     4921 attagtatga agaaaaagac atctgaaatg aaagaagagg caatatggat attaaacatt
     4981 tacgcttttt cattgctatt gtagaaaata attttaacct gagccgtacc gctcaacagc
     5041 tttatatttc ccagcctacc ctcagtatta tgattaatga ttttgaagaa aagcagggca
     5101 ttaagctctt caataaaaaa tacaataaaa tcctcggctt aaccatgaca ggcaagcaat
     5161 tttatgagga ttctttggag gttatccgca aatatgacaa gatgcaccaa aatctctttt
     5221 ccaccaatca aaagttggac ggtaatatca ctatcggcat tcctccatta attctgtcaa
     5281 ttgttttttc aaaaatcatg ccagaaatta ttctagaaaa tcccaatatc cactttaata
     5341 ttaaggagta tggtgctaat cggctacgtc aggaattgat tttagagaat gtggatatcg
     5401 ccattcttct gcatcctgaa cgaattgctg caaacaccat tgattctttc caaatccaag
     5461 aatctgagct ctgtgcattt gtctccaaga accaccattt ggccaataaa aaaatcctga
     5521 cttggataga actccacaat gaaaaactag ctatatttga taaaaccttc atgattcacc
     5581 atctcatcaa ggaaaaatgt aagtatactg acattaaccc ccaaatcatt ctggaatcag
     5641 cttcttggga ctttctgatc aattctactc gtatcaaccc tcaactaatg acgattattc
     5701 caaaaccaac ggtagatagc tatggttttc aggatattgt ggctattcct atggagaatc
     5761 ctattccttg gaaagtcatg gttagtcgtc tcaaaaaaga tcattattcc accatagaag
     5821 aatacatttt caacaaaatg cttgaaaaat ttcatgtaat cgaatagaga ctaacaagtg
     5881 atccctttca catgactgca cgtgcccttc gacatatggc acctcaacta acccttagcg
     5941 catatggaaa cagctcaatt ctttttgaag gataaaacta aagaggcttg acgatccata
     6001 ctaactcaga cccaatatta ttatcaagat cctaaatatt aacacaactc atttataaca
     6061 attaacttac aaaaaatggt ctactccttt gaggcgtgac agcaatactg caatttataa
     6121 aaaatgactg tcaagacaat atctctgaac tcagtcactg tttctcaaaa atcactcaca
     6181 tctaatggag tactatcaag aaaaagttat ttttaaaatc atcaataacc tatctaaatt
     6241 ttctaaacaa tgccatataa aaagagctgg agtcaccaag ctctaattga tttttacatg
     6301 atgctctata acaatatcgt ttaaagatca ttctttttta ctagtatgtt gatcacattt
     6361 tctaaaagcc agaaagagac ttgaataccg agtccctttt ctttttatct ataaacagcc
     6421 ttaaagaagc ccagacaggc tgcggtaatt ttcttaacat gagcttctac tatttctctt
     6481 gttaagccct gctcacttga tgattcgtta tttttaccac ctgaagactc tcctctacat
     6541 aggctacttt gtcatctagt tcctgcttct taacgatata tcatcgtctc aattgatgcc
     6601 acttccctta tcatcttaga aaaaagctaa tttctatacc tttaggtgtt ctagatcaca
     6661 aaatagcttt ctcaatccta tctaccttgc aagaattcat tgaatgccct taacttttgc
     6721 agtaacgaca ataaaaatag tttagataac gatgctattg atgttactga cttaccctct
     6781 ttattgataa gtatgctaaa tataagcaaa gaaatgcaaa agctaatcta atcatgacaa
     6841 taactaatcc atcaacccaa aaactgccaa aaaagccgtc ataagcaagc ttaagcatta
     6901 tgtttggtgt actcgcagtt gatacagata aaatactcaa caccttatga ggtattcctg
     6961 cttggaaaat atccataaga aaacttggta caaaaacact agccgcagac aaggcaaaac
     7021 ctgtcaatgg agacttaacc ttacttgaaa taaggatagt gatagccgta atcaggataa
     7081 gcccaataaa ctgataggtg actagattga taaatgttcc caaaagagtc attttttctg
     7141 gaaaagccat tatattcaca ttgctgttaa tccaatacag attgagttga acactcgtgt
     7201 cccaaccact taatccaaaa taccaaacaa agaccgctaa tattatggcg taaaaagtaa
     7261 caaacactga ggtgcttatc aagtaactac ttattatctt ggctatcgta agtttattac
     7321 gaccatacct agttgtcaat aaaataggat tcatattttt agcagtatca ccggaaaaaa
     7381 caggagcgat gaagtaaaca gacaaaagaa gaagaaggat ataagcacta tttatgacca
     7441 gaaaaagctg attccagggt gcaaaattac ccaacttcag ctctttaaag ggaagataag
     7501 agccaagagc cgtttgagat tttggggtga tcttactgaa atcaatagtc tcttcttttt
     7561 tcaaattaaa ataataatct ctaaattttg gatcaaaatg gctagttaca tagtagccat
     7621 acacattgaa gacaggattt tttgagctgc cacctagagt ataatctttg attgttctaa
     7681 ttaataactc attggacaat tgaccggtat gttcttccgc aaatcgcttg tttatctcaa
     7741 cagcatctct tccatgaatt ttatctatcg aagaaccact gatttgtcca ttaaaaaagt
     7801 tgatataaaa taacccaaag attgctaata agctaacaat aaacattccc aaaactgatt
     7861 tggttcggat cagttttttt aattcaaatg gtaagagagc tttcataaca cctgttcctc
     7921 tctaaagtga taaatgtata agtcttctaa ggttggtgac actagttgag ccaactgatt
     7981 tggtttctca tcactaacca cacgaaaaac acgactagat gaaactagtt tctcattgac
     8041 tacagcatac tgaccatgcc ttggtaacgg cgaaccatca gagacagaaa actcccagac
     8101 cttgccaaag atggttttca acaattcttg actactactc ttatggataa attgaccatt
     8161 ttttaaaatg ataatctcct tagcaatagc ctcaacatca gagacaatat gagttgataa
     8221 gataataatt ttgttggccg acaattcgct aataatattg cgaaacttca ccctttcttt
     8281 tgggtctaat ccaactgtcg gctcatctaa aatcaagatt ttagggtcat tgagtaaggc
     8341 ctgggcaata ccgagacgtt gcttcatacc accagaataa gaggcaatcc gcttcagacg
     8401 gacatcatat agatccacaa gttttaacaa ttcatccgtt tcttgcttgg ctttatgttt
     8461 aggtattcct tttaaggctg ccatataaag aagaaagtct cgaccagaaa aacgaccata
     8521 ataactaaac tgttgaggca aaaaaccaat atgctgataa aattcctctg attgaggttt
     8581 gtgatccagt aaaatctctc cttcatcagg agtcgtaaaa tgactaatga gattgagcaa
     8641 ggtcgttttc cccgtcccat tagcccctaa aagtccgtaa aggcctgggg tgaattgagt
     8701 agtaatcctt cgcaaaatat ttttcgatcc gtagctctta ctcaattgat ttaattctaa
     8761 taacatagaa ccctccttaa atgagtctac tgagcacctg taactcagta ctcagtagac
     8821 ttctcctgta cgaaatcctg ctgtctgtaa cctttattat tctcgtagca taatcaaatc
     8881 cagagatttt cgattcatta atgaaatatt gacgatgaca cctttttaat ttcccagcac
     8941 tttctccctc aatctgtctc agtgacgtag ctgccccaaa ttcccctttt agggtaacaa
     9001 atactactgt gtgaggctta gatgaatgtg ttgtcacatc ataggtttca gagattggta
     9061 atttaacaac tgacctattc ttatataaaa taacatattt cattgacgtc ctccttctct
     9121 atttatatct taatacaagt acaagcattg agacggtaaa gtctcaaatg gtatctatca
     9181 tatcctgaat ggtatcacag tagctgttta agatgtcata gaggcatttg agaaatgtaa
     9241 cctgttttcc tttcgttttt tgatcatatg atattgtatt agttcggaga accatggtaa
     9301 tcattcaaat cttacataaa cctctcttgg gatatggtat tagcgtctat attaattact
     9361 acttcaacag acaccttttt aaagctgcta aaattgtcag tggcaaacaa ataggctata
     9421 ggtataaatc tcacacttat tttatcataa aatcattctt tttatcatct aatcaaatgt
     9481 acaagcactt taaagttatt ctcatgactc tattattctt attggaagcc atattaatta
     9541 cgacgacatt ttcagaaatc attatcgtgt gtttggtatc atcgacacaa ccgctaataa
     9601 atcgtttaaa tgtatccaaa accaaattca tgattacctg ttcaaagaat aaccagaggg
     9661 cttactgatt gctttaacaa atatttctag tcttctcatt ttgtactcat ataaactcat
     9721 ctactctatt aaaaattgct gtgaacagaa aaaccttctc aacctgtttc agttttatag
     9781 ccgtagttag tttaaagtga aaccaccctg cattttctat acctaaatcc aattgacttg
     9841 ctttttcagc atcaacagtc atgctatcca taagataaca caccacgatg tgttgtgatt
     9901 attgttcttc tatatttagc cttacctcct gaaaacaaaa aaagagaaca ccttttaaat
     9961 gttctcatat aagcaatctt atatattaaa tgaggattcg atctaatgac aagacagcct
    10021 tattgctacc aataatgcag cttaccaaac aagggcaatc agtataaggg ttgctaacca
    10081 gctctgctga catagcctgc tttgagcgat caatactcct tctgattata gccaaagtca
    10141 gctaaatcaa gctttttgtc acgccagttt ttcttaacct tgacccaggt ctccagatag
    10201 accttatcgc ctagcattag ctcaatatca cgccttgcca gcttaccgat ttttttgagc
    10261 atggcgcctt gttttccaat aataatgcct ttttggctgt cacgctctac catgatggta
    10321 actcggatat gcaccttgtc agtcacctca tcacgcttca tcgaatcgac cacaacagca
    10381 actgaatgag gcacctcctg ctgtgtcaag tgaagcacct tttcacgaac catctcagaa
    10441 acaagaaagc gctctgggtg atcagtgatt tgatcctctg ggaaatactg gaagccctct
    10501 tcaaggttat cctttaagag ctgaacgagc gtttcgacgt tgtttccttg aagtgctgaa
    10561 ataggaacaa tttccttaaa gtccatctga ctacggaaat catcaatctg ctccaataat
    10621 tggtctgggt gaaccttgtc aattttgttg atcaccaaaa taaccggaat acgagcagcc
    10681 ttgaggcgtt cgataatcat atcatcaccc ttaccacgct tttcatcagc aggcaccata
    10741 aaaagaaccg tctcaacctc acgcagggta ctataggctg attccaccat aaaatcacct
    10801 aaggctgtct taggcttatg aatgcctggc gtgtcaataa aaacaatttg ctctgtctct
    10861 gtggtataga ttcccataat tttattacgg gttgtctgcg ccttatcgct cataacggcg
    10921 attttttgtc ccatgacatg attcaaaaac gttgatttgc cgacatttgg tcggccaaga
    10981 atggcaacaa agcctgattt aaacataagc tactaagggc ctaaaggatc agtcaaggta
    11041 agaatcaagc agcaggctat tcacctgatt gctttcctaa agcttatact cctttcctgc
    11101 gctgcactat cgcacaggat agcccatttc ctttcatttt tttaatggca taacattcgc
    11161 caaattttgg gaacaaagat aatcagcccc gtcaaaacag catagcctga aatgaccagg
    11221 acagcacctg cagccatatc cttggcatgc ttagccagca tggagaaatg gtaatcactt
    11281 gccaagtcaa ccacattttc aatagctgaa ttgacaatct ctaaggtaat caccaaaaaa
    11341 atagccagca ataaaaacag ccattctata gcagaaatac caaaaacaat cccagccaaa
    11401 gaggctaaca gggctgacaa aagatgactt cttaggttac gctcctcctt aaaggctgtc
    11461 agaacccctg tcaaagcaaa ttctaagctg gcaattactg ttctgttttt ccatttgcgt
    11521 ttattattgt cttgtgaggc cataagcagt caaaatctct tcctgtaacg taaacatctc
    11581 tttttcttcc tcaggagtgt aatgatcata accattaata tgcaaaaaac catgaacagc
    11641 caagaagccc atctcacgct caaaggaatg cccataggct tctgcctgct catgggcttt
    11701 gtcaacagaa ataaacagct ccccaatata agcatcaaac tcctgtatca tacctgccaa
    11761 gtcaggatca agctccaaat cctcttggct aaaggcgatc ggaagctctg gcttgtactc
    11821 cagagaaatc acatcagtcg gacgatcagt atcacgatat tcaagattca aggcgtggct
    11881 tctatcattg gtcacaaagg taaccgccat ttccttgtcc tctttaccaa ttgttttggc
    11941 agcaaaattg agcaaatcaa tggtttgctc catcatctct tgagaaacct gcttagtttc
    12001 atcaatcatc tctatataca tcattatatg aagaggtcct agcaagacag gtccaaacaa
    12061 acaccacact gctaggtcaa aaagcttgat acctcttatc ctttcaacat catttcagta
    12121 ctttctttcc attataccac aagaaaaaag aaaaagcagg cattagtcta gcctgctcca
    12181 aaagaagccg gaataatgac aagatcgttg ataccccagc agctgctgtt tctggaatac
    12241 ccagagcctg ctgcgcagaa tacagtcctc ttagatagct gggactccta ggattacaat
    12301 agtagataag cctttagacc acttccatcg cctaaaaact aatcctaaac ggctttccct
    12361 tagataccac tagctgctct caaagctatt gtggaggtaa cgatctggct tattggctga
    12421 cgccagtgat ttctgcttgt cataatcttc tttggttaaa taatagtgca gcactgtcac
    12481 aaaacggttg gaatcaaggt gatcacgctt agcatatggc tcttcatgtg aaaagcacat
    12541 gccgctttta gccataacac gtcccaaagc cggattggct ttatcatgct tagcaatcac
    12601 acaattcatg cctaaagctt caaaacacaa gaccagtaca gccttgacag cctctgtcgc
    12661 atagcctctt ccccagtgat gcttatgaag acaatagcca atctcagctc tacctaaatc
    12721 cagctgtata tgatgaagat caagcgtccc aataaagtct cctgtttcct ttaacacaat
    12781 cccccaccgt ccaagtggac tagccagata gacagaagca atgacttgac gggtctcctc
    12841 aattgtctga ttggctggaa agctatacct gacagtctct tcatcagaag cataatcaaa
    12901 catggctttg gcatcatcca aggtcactgg acgcaggcat agacgctctg tctcaagata
    12961 cctatgctct gctagttttt caaaaaagct tgccactact actctccctt tcctaaaaat
    13021 ctaactcacc taacagcatg actgcctgcc ctagccgcgt aaaatctgcc tcaccttatc
    13081 ctttaaaaca ggaaccagct cctcttcaaa ccaagcattt ttagccaacc aaagctgatt
    13141 tctaggagat gggtgaacaa ggggaaaata atccggaaga tagtcctcaa aatgctgcac
    13201 cgtttcggta agattgcgtc tacaaccttc accaaggtaa tattgctggg catactgtcc
    13261 gaccagcacc accaattcaa cctgaggcat caaggccatt aacggaccat gccacttggc
    13321 agcaaagccc tttcgcggtg gtaaatcacc tgattttccc ttaccgggat aataaaaatc
    13381 cataggaaga acgccaaaca agcccgactg ataaaaggtc ctgtcatcaa cacccagcca
    13441 agctctcaag cgaactccgc tacgatcatt ccagtacaga cgcgtctcct gagctacaat
    13501 accaggcgcc tgaccaacaa tgactatccg agcggtctga ggagctgcat aaagtggttc
    13561 gatacctttt ttggtatagt cacgattggc aggatcagcc ataatcgctt gcaatagctc
    13621 tgtcatgata ccctcacttt cataaaaggc tcttcaggtg aagagctctt ttttacgatt
    13681 tgtcttcttt aggcagctct ccaatgacct cataggttgt taagcctgac gtagactgac
    13741 ccgtctctgt tttaggccga tctggagcct tagtctgatg ttgcagctga ttagggctgc
    13801 tttttaatga ctctgctttt gaacctacag tttcataggc cttaataatc tcagcaacaa
    13861 cagggtgacg caccacgtcc ttggctgaaa aatgcacaaa atcaatctgc ttgatggcct
    13921 gcaatttttg agctgcatca atcaagcctg atgtgatatg acgcggcaaa tcaatctgac
    13981 taatgtcccc attaacaatc attttagact gaaaaccaag tctggttaaa aacatcttca
    14041 tctgcatgat ggtcgtgttt tgcgcctcat ctaaaatcac aaaggcatca tctaaggtcc
    14101 gaccacgcat ataagccaag ggagcaatct caataatatc acgctccatt aaccgagtag
    14161 tctgctcttt accaagaatc tgataaaggg catcgtagac tggtctaagg taaggatcaa
    14221 ccttttcctt caaatcccct ggtaaaaagc ctaagctttc tcctgcttca acagctgggc
    14281 gtgtgagaat gatccgctta acctgaccac gctttaaagc agtaactgct agcgtaactg
    14341 ctaaaaaggt ctttcctgtt ccagccggac caataccaaa taccacatca tgatgcttga
    14401 tactatcaac ataggccttt tgccctagcg tcttaacacg aattggcttg ctataaaagt
    14461 ccttgataat ctcttcctca taaagagcaa caaattgatc aagcctatct gaatccgcca
    14521 tagacagcgc agtcaccaca tcagaggtat tgataaccat gccacgcccc accaaaacta
    14581 aaagggcttg tatcgtcaaa cgcgctagct caacagcccg ctcatcatca ccaataatct
    14641 gaactcgctc agttctagca tgaatcacaa cattgaggtg agattctatc atcttcaaat
    14701 ggcgctcatt gctaccaaaa agagctaaca gatcatctgg gtgattcaag ctaatgtcag
    14761 tcgaataatg caaatttgtc ttccttttcc atctataagt aactctatta taacaaattt
    14821 tgctataaat cgggaataag acccagcttt aaagcctaaa agagctagcc tatggctagt
    14881 ggctaaggta atcctcccaa atctggtcaa actgccccag attgaatgaa aagctcgctt
    14941 cctcttcaag gtaacgactg atggtctcaa aatcatctgt atgctttgga aaggtcgggt
    15001 cctcaaaaac caaatcagct aataaagcag caggcttatt agatgtcgag ttgcgctgag
    15061 ccatcagcca agtgtaaaac gcctttctca ttgccaatgc tcctccaaaa attgatgacg
    15121 aatagcacta ctttgtgcat aacgctctgg attcttttga taaaagccct gatgatagtc
    15181 ctctgctaga taaaaaggct ctgccggttc aatgcttgtc acaatgggct ggtcaaagcg
    15241 ccctgaggcc tgcagggtct gcttggaccg ctctgcaatt tcccgctgcc gctcatcagt
    15301 atagtaaatc accggccgat agttgtctcc tctatcctca aattgcccaa aggcatcggt
    15361 cgggtctgtc tgagcccagt aaagctctac caaatctgaa tagctgatca gactcggatc
    15421 aaagataatc tcaacagctt cagtatggcc tgtcgtcttt gagcaaacct gctcatagct
    15481 tggattgtga acatgccctc ctgtgtagcc acttctcact gataaaatac ctgcctgctc
    15541 ctcaaaaggc tgcaccatac accaaaaaca gcctcctgca aaaattgctc tttccatacc
    15601 taatctccac tttctttgtc cttacattag tgattttcat tgtaacaaaa aaccttgcca
    15661 gaggcaaagc ttaatataaa acaagtcaca gactcaaagt aacaagactc ctcagcccaa
    15721 ctagtgccta gcactaagca gtactgtcaa gcagccacta ctagatcaag agggccacac
    15781 agagcttttt cgacaacaaa aatgattggc gctttaaaac aggctatcag ctaagctcca
    15841 cactcaaaat aaggaagcta gctatactga taaaggataa gtcttagcaa caccgatcca
    15901 gcttatgatt ataggctaag agacagacag ctccctatga tatcagctca gttcctgtca
    15961 cgtcctgctt gatcttgtta gccttcatca aaccacctaa ggccttttta aattgaccct
    16021 tggaaatccc aaaggttgcc ttgatatcct ctgggcttga cttatcatta agagtcatgt
    16081 agccaccatt agacttgaga taggtcagaa tcatctgggc atcgttttcc agcatttcaa
    16141 aggaacgcgg ctttagcgaa aggttgaggg tacggtcacg ttctctaaag ccaatcaccc
    16201 gagcggtcaa aacctgcccc aaacgaggct ccgtataacg ctcgctaggg tggataaagc
    16261 ccagcatatt attttctggc aggtaaacaa aggtccctga tagcttcaag cgatagacaa
    16321 tagcaggcag gctttgattt tgcatgttat cataggctgg actagcaagc ctttgaaata
    16381 tctctggctc agctggcaaa ccccagatac gatctttttt gtcaaccaca agcttaagat
    16441 aaagcctgtc tcctttttta ggccaaagat cctttagctc cggcaaaaca tctaaggaaa
    16501 ccacaatctc cttatctgga ataccagtat caacaaacac cccaagatca cgacggacag
    16561 tggtcacctc gccccagcca taatgatcac gccttgcgtc aataggcttc gtggtcaagc
    16621 gtagtctttg cttcatatct gtatagacaa agcccttaac catatctcct aatctatgac
    16681 tgccttcctc cttagctaga gcaaagctca gcccctcctt ttggacaaga taaaactgac
    16741 tattttcttc ttttactaag ccagtgataa ctgttgctaa taaatgattc atatcttttt
    16801 gttctttctt ttaaaaaata gggacaagtc caaagcagct gctttttagc cttgtcacct
    16861 atcctgttat gcctgatgtg tattaggtta cgcagctgat ctagcttaat gatcagataa
    16921 gccgcttaaa ctgaaagtaa ttccttttct ttgtcagcag tcattcggtc aatctctttg
    16981 acagcctcat ctgttgcttt ttgaatatcc ttttccaagg cttttaactc atcttcagtg
    17041 atttccttag ccttctcctg ctttttagcc tcgtccatag catcacgacg aatattgcga
    17101 atcgaaacct tcgcagtctc accaaccttt ttcacttcct tggctaattc cttacgtgtt
    17161 tcttctgtaa gcgctggaat aaccaagcgg atgacagagc catcgttagc tggtgtaatg
    17221 cccaaatcag aagcattcaa ggcacgctca atatccttga ttgatgattt gtcaaatggt
    17281 gaaatcaaaa gcacacgcgc ctctggtact gtaatagaag ccaattggtt caacggcgtt
    17341 ggtgcaccat aataatccac ctgaatacga tccaaaaggc tagcattagc acgacctgca
    17401 cgaatgcttg catactcgcg tgctagtgag tgatgtgact gtgtaaaacg ttctttcgca
    17461 gtttcaataa ttgcatttgc catgattgtt tttctcctta atcctttagc tctaaaatcc
    17521 taatcgcagg ccttatttga taccgttgtg ccaatatgct ctccaaagac cacacgcttg
    17581 atatttcctg cttcattcat attaaagaca accaaatcaa tatcattatc cattgacaag
    17641 gttgaagctg tcgcgtccat aatcttgaga ccgcgcttga taacctcccc atgagtcaat
    17701 tcatcaaact taacagcgtt tgcgtccttt cttgggtcag cattgtagac accatcaaca
    17761 ccatttttag ccatcaagat agcatctgcc tcaatctcag cagcacgtaa ggccgctgtc
    17821 gtatctgttg aaaaataagg tgacccaata ccagcaccga aaacaacaat gcgccccttt
    17881 tccagatgac gaagcgcacg acctcgaata taaggctctg caacgttttg catgggaata
    17941 gctgtctgca cacgagtatc aacgccataa tgctgaaggc tatcagccat tactagagca
    18001 ttcataacgg ttccaagcat gcctgtgtaa tcagcctgca cacgatccat accagcctct
    18061 gcagcaggct caccgcgcca gagattacca ccaccaataa caagagcaat ttcaacacct
    18121 gaattgtgaa cttctgcgat ctctttagca atcgactgaa ccgttgttat gtcaatgcca
    18181 acacccttat caccagccaa ggcctcgcca gacaatttga ttaaaatacg ttgatattta
    18241 ggtttcacta tttatgatct ccttattttg tccctaccat tctaccacaa aacaaaaaaa
    18301 tttaatagac caatgcaaga gaggaaagcg aaatttttga cgatcctttt atcaagatcc
    18361 ctttgagcag caaaaaagat gagtcattat aaaaagagca ttatcgtatc cgaatagcac
    18421 agttataacc tattaatacg acaaaaacca gaacaactat gacaaaaaac gccgtaaaaa
    18481 agacttaaaa tcaagcctca agccagacta gattctaagt cgtgctatat tgagagatga
    18541 tttgttttag ttatctagcc caatgccgcc acaagaagtc tgaggctcct tatctctgac
    18601 agcaactagc ctcccctgct ccagcagcag aacacgatga caaatggcct gacagatatt
    18661 agcatcatgc gcaataaaaa tataagtcag ttgatactcc tgctttaact catagagcaa
    18721 gtccaatagc tgcccttggg taatagggtc caagccactc aaagcctcat caaaaatgat
    18781 cacctccggc cttaacaaaa gagctctcgc tatacaaaca cgctgtagct gaccaccact
    18841 cagctctctg gcctttttac ccagatgagt ggcgtcaaga ccgaccgcag ctagtatttg
    18901 aacaacctcc tctaaggcaa agtccttaga aagggcctct gtcaatatct cttgaatagt
    18961 aaagagggga ttgactgatc ttagcgcatc ctgaaagaca agtaaaatcc gaggtccaca
    19021 tacttttaca gaatagggct gaccatgaaa gagcacctga ccagctgtcg gctgctctag
    19081 cccaatgatt aacctagcaa gcgttgtctt gccactacca ctttctccca taatcccaag
    19141 gctctcaccc ttttccattt gaaaatgaca atctgttagc actggctttt gatgaaagct
    19201 cttataaaca tgtctaaact ctatcatagc gtatcagccg atcataatga ttttgcaaaa
    19261 gcaactcctt ggtggcagcc tgacttggcc gatgaaaaat cgactcaaca cttccctgtt
    19321 cgatgatttt tcccttactc atcaccagta gttgccctcc caaagtctgt gccaattggt
    19381 aatcatgcgt cactgtaata atggtttttc ccttgtcctg caataacttc agcatccgta
    19441 tgatattaga acgattggca tcatctaaag cagaggtagg ctcatctaaa atgataatct
    19501 gtgggtctaa gcacaacaaa atagctagca ttacccgctg tagcatacca ccacttagct
    19561 caaaggggta cttcctcagc agctcctctg gctgctctag atagagctct cgcatgaaag
    19621 gcagagccct ttttagacag gccctttttg aaagtctctc atggcttcgg atggtttcaa
    19681 ggagatgagc ctcaatggtc tgaaagggat tgaacatcgc cataggattt tggaccatat
    19741 aggccatgtg gcgccctcta atgctctgcc attgcttagc atctaattga tctagtctca
    19801 tatcttgaca ggtaatcctc cctgtcatct gtacattcga cgggcattga ccaattaata
    19861 gcttagtcaa gagggtcttg cccgaaccac tcctgccaac aatcaccaag gagctcccca
    19921 agggcaactc aagattgagc ttacttaata gcacatcaga gccattataa gccgataaat
    19981 cattaacaat taaccgttcc atgttttcct ccacccctta gcatcagcgt aatcacctag
    20041 gctgttaaaa gctagcacag tcactaaaat ggcaagccct ggtgacatca tgagccacag
    20101 agctgtccta aaatagctcc ttgcatcatg cagcatcatt ccccattctg tcacattggg
    20161 ctgaacaccg atacccaaaa aagaaaagct tgagatcatg agaataatat tgccaatatt
    20221 catcaaagcc aacactacaa tcggccgata aacaaatggc aggatatgct tttttaagat
    20281 atgccgcaca gataagccca ttgtctgcgc actaatgaca tatggctctg ccttagcgct
    20341 tttgaccatc gtgaccatca gcctagcata atacagccac tctaccagaa caatagctag
    20401 gatcatgttg cctatgccct gcccaagtat ccccattgta gctagcgata gtaaaaagct
    20461 aggaaaggca gaaacaacat cagctagcca cagaaaagct gcctcgagcc ttccttgata
    20521 ccagcctaca accaaaccaa ccacagcacc aatagatagc tctaacaaac taatagtaac
    20581 cgccaaaagc aaggaatact tagccccata taacaagcgc gacagcacat ctcttcccaa
    20641 ttggtcagtt cctaataagt gctgctgact aggtggcatg agcttactag caacatcaac
    20701 agcatgagga tcaaagggag caagataagg agcaaacaag acacagataa acaacagcaa
    20761 tagcataaca gctgaaccaa ttacgtattt gggcatgctt cctcctttgt cttgcgcaga
    20821 cgagggtcaa taaaagacac tagctcttga gttatcacat ggtgtagtaa aaacaaagca
    20881 ccaaataaga gcatacaggc ctgaataacc ggaatatctg ctgctttcag actcataaca
    20941 aatagactgc caataccatt ccatgagaaa atatcctcaa caataataga gcccgtcatc
    21001 aaataaacaa aggtcaagct caagcctgtt gcaatagcag gaaaggcatt tctaatcagg
    21061 tgatgcttaa caatataata ggtcttaacc cctcttagcc tggcattttc aacatgcaga
    21121 ctcgttagct gctcactgat tgcctttcgt atcaaggcag tatattgccc aatcaaggaa
    21181 aagctaagcg taatactcgg caaaatgagg ctgctggcac ccgccttgcc tgacacaggc
    21241 aggagattta gcttaacaga aaaggctata atcaagagat agcccaacca aaagctaggc
    21301 attgacacag cgacaaagct gaataaacgc accagccgat caaacaagga atgctcaaac
    21361 aaaccactgc ctacccccaa aggaaaggca atcacaagta ccagtaaaaa agaggtcaag
    21421 cttagcatta gcgttgctaa aaagcgctcc accaccaaag gcaggacagg gacctttaac
    21481 acgtaagagg tcccaaaatt tcctacaaga atgtcagata accaggtcac atactgctcc
    21541 cataaaggct tgtctaagcc caaatagagc ctagcattgt gaagagcttc tggtgtaata
    21601 ctgatcttag ataggcgcaa atactgctct gccgggttag cggaggatag cttaaccaga
    21661 acaaaggtca ctatcgaaat cattagcaag gcgccaaagg tagaaataag cttcttcatc
    21721 atattttctc tcaacccttc actaagacat cagacaagaa ttgtcaggat agtcactcac
    21781 aaccagttcc tctgctctat caattcttga ctgccttatc agcagcactt ttttcaatgt
    21841 aacgcaatgg aagggcattt tcctctggtg caaagcgcat tgtcttaaaa tctcccttgc
    21901 gatatactga aacaactgac tgataggtga gtggaatata aacagcctca tcatgcaaca
    21961 atgacaatac ctgcttatag cccttgtcta ccttatcccc atctggctca atcaaaacag
    22021 atttaatcag gcgatcaatc tcagcctttg atggcaaact ctccaaggca atattttctg
    22081 ggtgaccatg atccgctttt gccgttaagg ctgtcatcca agcatgagga tcccaaggag
    22141 ctccccatga ataggtcagc atcatatcaa actgccctgt cttggcatta gcccagtagt
    22201 catcctcctc catagctgtc aagaccacat caatcccaag ctttttccac tcgccttgga
    22261 aatattcaac caaatccttg tctgtcgctt tagttgaaat ataaggcacc tgtaaacgca
    22321 actgctgacc atctttttcc ctaatccctt cttggttttc cttccagcca gcggctgtca
    22381 gcatgtcctt agccttttgg agattgtatt cataaggaac taagcccgca tcagcatgcg
    22441 gtgttgtttt tgaaaaaatg gtatctgctg ctgtctctgt tcctctaaag gtgtgcttag
    22501 caatagcctt tttgtcaacc gcatggttca ttgcctgacg aacccgcttg tcctgaaaca
    22561 ctgactgctt agcatttaac agcaataaac gagtcgacat gggctgagaa acatcagtaa
    22621 catacttctt gtccttagca tactgcacaa aggtatcaag actaatcaga ccatttccat
    22681 agatcaaatc aatatcccca gcctcaaatg ctaaggctct tgtctcagca tcaggcataa
    22741 tcttgatggt tacttccttt agctttggtt tttctcccca atagctctca tgacgtgtaa
    22801 aggtaatgta ctcatttgcc tttttctctt taacaaccca ttgacctgta ccaatcggct
    22861 ttttaacatt gtgcttattg gtgtcatcgc catcaggaaa accagcatca gccaaaaacc
    22921 taatcggtct gatcattgac aaatcataca aggtagcgct ataagcctcc tttagcttaa
    22981 tctcaaaggt atgatcatct aaagccttgt agctatccaa ttgattggta aagtgaaacc
    23041 aattatgatt gcccttattc tgctcagaga aaatcgaatc aaaattccgt ttaacatttt
    23101 gagcattaaa atcagaacca tctgaaaatt tagcctgtct caggttaaag gtataggttt
    23161 tgccatctgg gctaatcgtc cagctctctg ctaacgccgg ctcaatatta cccttgtcac
    23221 catatcgaac caagccctca taaaccatgt cttgaataac aaactgatca ggattgtagc
    23281 gatgaggatt gacatcacca aaatcctcac cccaagcaat cctcaactga tccgtacggt
    23341 aagaggcctg cttagcattt tgacaggccg tcagcagcaa agcaaaaaag aataacaata
    23401 gcacattcaa tttagttttc attatgtcat taactttcta aagatattaa tctatctaat
    23461 tttagatgtg gtttatcaca aaattaagta tggttaattt aatca
//
LOCUS       DARYNN010000034        22690 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.034, whole genome shotgun sequence.
ACCESSION   DARYNN010000034 DARYNN010000000
VERSION     DARYNN010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22690)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22690)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22690
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.034"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(92..562)
                     /locus_tag="TVB59_001335"
     CDS             complement(92..562)
                     /locus_tag="TVB59_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEL1010225.1"
                     /translation="MLEVIKNWVNICVKEGDKILLLNRQHDDFPGWIQPGGKVNTSES
                     FFEAAVRELKEETGLTALNLQLKGISGFTNPDKPERYVYYDFLCEDFEGKLLTKSREG
                     LPQWHAIADLDKLDMQEDIRQRLPLYWRQGSFERLHYWSDKEKKVVKTITHLYD"
     gene            783..1633
                     /locus_tag="TVB59_001336"
                     /pseudo
     CDS             783..1633
                     /locus_tag="TVB59_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622164.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
     gene            1969..2259
                     /locus_tag="TVB59_001337"
     CDS             1969..2259
                     /locus_tag="TVB59_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009853345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uberolysin/carnocyclin family circular
                     bacteriocin"
                     /protein_id="HEL1010226.1"
                     /translation="MATLERHHKMLLLSMALGAASWLALGLISLPNLAGALGISTANA
                     NTTVNLLSAYSTVSSVVAIVGAVTGVGSIGAGIAATVLYLIKQKGKAAAALW"
     gene            2273..3412
                     /locus_tag="TVB59_001338"
     CDS             2273..3412
                     /locus_tag="TVB59_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010227.1"
                     /translation="MKHVFKYHKGDILGYLNIVGFTLLFYGSVIGMIMFRDYLTYDGA
                     GSLISTFILVSGTYHSVKSTFPYEGKRHPTFILTPYYLFKHLLLSVTKVYAFQIRVVT
                     IGIICLAIAFPEQLVWIALSVLAVFIYWLSLPLVAIFRVAGRLLNLLMIYGMYLNQEL
                     LVIACLCLNVVILVLSVTINVHYPYQWLAVRARKEEKTITLLKLVINTITDHLALMVL
                     FSIFCIAVTYFTQRLLLSFDYSSFSIPVFFLSASTYIALLEVMVGKNIKELELDRGLA
                     VLQFLNRDISVYKAYRNSQFLLSAHILAVIHTGCAIGLLPFLLNGQAALFLSNLVMIP
                     FIYFISFCYFVKSLKIVAGDLSVFRWVILVLYFILVVIAMVGSRL"
     gene            3409..3891
                     /locus_tag="TVB59_001339"
     CDS             3409..3891
                     /locus_tag="TVB59_001339"
                     /inference="COORDINATES: protein motif:HMM:NF014052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HEL1010228.1"
                     /translation="MIMRKFLRYYISFIIFSIAIGILIGLLITSDTVILSKPERGWDF
                     TLEVLKNNSNNFLSYIFLFFLSPALQLIDLVSVVIQITLGMRKSGFLITALGLFPHGL
                     LEIPNFLFYQGLSQYMLWTVLTEKSMTSFLERERRYVRYYLISYYVLLIAGIMEGLLG
                     "
     gene            3888..4475
                     /locus_tag="TVB59_001340"
     CDS             3888..4475
                     /locus_tag="TVB59_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1010229.1"
                     /translation="MKIVNESKSFSNRKILNHISFDFSKGLYKVEGNNGSGKTTFLRL
                     LAGLERFDSGHRLQHKGDILYLDTNAIGVVPLTIEDNLTLLWKTFNASPDEETLSVIN
                     QFFGERLLDHYLTASVGTKAKVGLSLLFVKDWDYIFIDEALSTLDGFSLDMVAGRLLA
                     LKEKATVFYVSHNLSHQQLLSESQVIYLNGKGEIY"
     gene            4472..4954
                     /locus_tag="TVB59_001341"
     CDS             4472..4954
                     /locus_tag="TVB59_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010230.1"
                     /translation="MKGNPFNRNLSWLIAYVLLLSCYVFILVDGGFLKNSVQELEVLL
                     GQTSLAIKLFLMVISIAFSIISLLVEYFLSKFLVLLFIEAGIVSLNDVLTAKSVTLVI
                     HLSALLLKLSPSPLFQFVVNALGIVIMYGLSIKRQGNRTTALLFCLPFTLDILATLLL
                     "
     gene            4979..5494
                     /locus_tag="TVB59_001342"
     CDS             4979..5494
                     /locus_tag="TVB59_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010231.1"
                     /translation="MKKILYLSVLLGTSILATLIKIYNTFFAKLKASSGHSTGNIEID
                     ALLSESRLVLERQHAFTTNGINKLFVMMMSLMLLLALYYLIKKDLKAVYSYLLYLVLT
                     LVHAIYSFFSLSPLAKLYSDDMLGATIQTGEKAKLIFSVVLFLLYLLIVVANNRVKSS
                     VEPASSIGIDV"
     gene            6128..7762
                     /locus_tag="TVB59_001343"
     CDS             6128..7762
                     /locus_tag="TVB59_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010232.1"
                     /translation="MTRFFQKKQAKSLAIGFVSLFAVLIGYGAFHYSKASRINAYLQA
                     RSSGSGQVLENIKEYLVWADTNEQLTNDQARYTSFKRYSKAELVSKRQQLQTATAADD
                     MYVKSVGRKFLIFPDYRIAVKPVALTIKTNVPNVDILLNHKKIAVSQSEDFSTTIERL
                     PAADYKASINGYYKDRKIKVSKAYDGKNHTLDLRVTFKTFTVTSNVRDGELYIDGERV
                     ETLKAGQLQLEEYPVTEIAKAYIKKTFPDGELTSSKHSLAPVAEGSQLEINIDHLLTE
                     EQAGQVLVAAFDQLLTYLNQGQDPAGLSTVFEQGANNAFYKGLKDSIKAKFQTDTRKA
                     SRLSIPSILLSKLTQIGKQSYLVDFTAVYDFVYDKETDPEKGTSGNVRQDLTGKLTLK
                     KSGDSYLVSQSGPKNITVASEKNQVKPSIFPEGLVGTWIGHRSDMTFTMILAKDGSIT
                     TTIGNKNGNGSQTTKSAKITKVEEKGDGLFLYTVAPDADIAALVPGGGLGGVNVKYAF
                     GVKWSGDVATIVVWQTANNAAFDYSKPMLGPDMKKQ"
     gene            complement(7903..8796)
                     /locus_tag="TVB59_001344"
     CDS             complement(7903..8796)
                     /locus_tag="TVB59_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEL1010233.1"
                     /translation="MTTANKPEMGFQISFINPYQATTVKELLEDRLLIPRKIRHFLRI
                     KKHVWVNDELINWQSPVKQGDHIKLQFDQEDYPDKGILMGKPGLVDCLYQDEHLIIVN
                     KPEGMKTHGNEPTELALLNHVSAYTGKTCYVVHRLDMETSGAILFAKNPFILPILNRL
                     LEHRDIKRDYWALIEGQLEQQTVTYRDPIGRHRHDRRKRVVDSKHGQEAITHLALLQA
                     FDQTCLVNCRLETGRTHQIRVHLAHHKHPLIGDPLYSRQKAERLMLHAHQLTLRHPLA
                     QEMIRVTAPSKSFKEGLQQLN"
     gene            complement(8780..8971)
                     /locus_tag="TVB59_001345"
     CDS             complement(8780..8971)
                     /locus_tag="TVB59_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010234.1"
                     /translation="MNKFQAFKETLSAESLKAVYDETRLEVASDEREGTEAFSVTLAT
                     QMAINLIEKYHDWLNDNSK"
     gene            9206..10960
                     /locus_tag="TVB59_001346"
     CDS             9206..10960
                     /locus_tag="TVB59_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein"
                     /protein_id="HEL1010235.1"
                     /translation="MNKPLIKSCLLALLTLAGLTSMAAQADVNTYNQGRTYNDTPYYS
                     AYHHYYDHTRDTADNGIDNWGRLTRYHYYRETYYQLEAERQQLVRTYLELKASYDDQV
                     ALSSQRLQQYQSGWSDLQSRFEQLRKTNPVVGGDYRIVELEGNFQSYQTLLQQLSMAD
                     FVSQYKDRLDTLTRLDTERARLIDTWWESDSNYSDLNTNLTLVNGYIKELNQALQELL
                     KDHQGKMTSDLQTLGDRQAELARRLTDIESRPKRQATSQPRGSQTHWRSAPRADVALW
                     NELRNEGDYASATTDNALPLQPYRADLTAVHDLEALQAQSDRAHRLRAKEIVFTLQRS
                     NISRQGDIDLSGAITAFIKEKLLVTPNARGVSSGFRWQMQTYDNERLTITLMPQYYMT
                     DDQYKEYYDHLKAWTAQHIQSTDTEVEKIDKIQDYIMTNYHYATGKVGGVTRTGISVQ
                     TPYAFIKDKEAVCQAYAQMFKDMGRLAGLDVHYIQGYGDPVGGLSSLHAWNIVKVDGQ
                     YYHIDLTWNDTIDSTNHNHTYTLRGNDFMSKTHLWNAAYAISDSDYAAYPRRSFLRYG
                     TYATNYSRNTFYPGYSYA"
     gene            11101..11481
                     /locus_tag="TVB59_001347"
     CDS             11101..11481
                     /locus_tag="TVB59_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEL1010236.1"
                     /translation="MKSIRRYDVNEEWAHTGLVEAGDFYFLNYCVGNVGQDIEAQING
                     AFDEMERRLGLVGLTLEVVVQMDCLFRDIWNVPVMEKIIKERFNGKYPARKFLQTAFA
                     HQGGPDGLLFQVDGVAYSKHISVS"
     gene            11519..13852
                     /locus_tag="TVB59_001348"
     CDS             11519..13852
                     /locus_tag="TVB59_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEL1010237.1"
                     /translation="MTFLELLQKKFFPKKYQEKQALKERAAQHMADKEATTQATATAL
                     ADQEAQAGQTERQSVLQRSKSYGVKRKNRPIWLQRLEAILPSQQGPIRRFLRRYHVGK
                     ILLILMGTFVLLLGSYLFYLSKTAKVSDLQDALKATTVIYDRKGEYAGSLSGQKGTYV
                     ELDAISDDLEKAVIATEDRTFYTNNGINFKRFLLAIVTAGRFGGGSTITQQLAKNAYL
                     SQEQSIKRKAREFFLALELTKKYSKNDILTMYLNNSYFGNGIWGVEDASQKYFGTSAA
                     NLTLDEAATLAGMLKGPEIYNPYYSIEKATNRRDTVLSAMVDAGKISKQQAQEAQAIG
                     MGNRLADTYVGKTDDYQYPSYFDAVINEAISRYGISEKDIVNDGYKIYTELDQNYQAG
                     MQTTFNEDSLFPVSEFDGSSAEAASVALDPKTGAVRGLVGRVNSTENQPFRSFNYATQ
                     AKRSPASTIKPLVVYTPAVAAGWSLEHELPNSVQDFGGYQPHNYGNYESETIPMYQAL
                     ANSYNIPAVSILDQLGVDKAFSYGEKFGLKMSETKKELGVALGSGVTTNPLEMAQAYA
                     VFANGGVKHIAHLITRIENAKGKVIKTFTDKTKRVISQSVADKMTSMMLGTFSNGTAV
                     NANVYGYTLAGKTGTTETDFNPDLSGDQWVIGYTPDVVISQWVGFNQTDEHHYLSDSS
                     AGTASAIFSTQASYILPYTKGSQFKVDNAYAQNGISAVYGINETNTQAGIDSQSIIDS
                     LRKSAEEASKSISEAVDQSGLREKAQSIWKSIVDYFR"
     gene            13901..14053
                     /gene="rpmG"
                     /locus_tag="TVB59_001349"
     CDS             13901..14053
                     /gene="rpmG"
                     /locus_tag="TVB59_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEL1010238.1"
                     /translation="MAQKKASLACVECGSRNYSIGISSTPRPTRLEVNKFCKYCKAYT
                     LHKETR"
     gene            14065..14241
                     /gene="secE"
                     /locus_tag="TVB59_001350"
     CDS             14065..14241
                     /gene="secE"
                     /locus_tag="TVB59_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEL1010239.1"
                     /translation="MGFISGIFKLLRDTTWPDRKQRWKDFISVLEYTAFFTVIIFIFD
                     QLLSKGILSLINLF"
     gene            14632..15177
                     /gene="nusG"
                     /locus_tag="TVB59_001351"
     CDS             14632..15177
                     /gene="nusG"
                     /locus_tag="TVB59_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEL1010240.1"
                     /translation="MLDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEI
                     PTQTVNVEKNGQVKEVEENRFPGYVLVEMVMTDDAWFVVRNTPNVTGFVGSHGNRSKP
                     TPLLEEEIRAILLSMGQTVDVFDTNIKEGDMVQIIDGAFIGQEGRVVEIENNKVKLML
                     NMFGSETLAEVELYQIAELSS"
     gene            16220..17737
                     /locus_tag="TVB59_001352"
     CDS             16220..17737
                     /locus_tag="TVB59_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1010241.1"
                     /translation="MSIENLFTKQQWRELELITLLSETKNPLYYKDACQMLDCSVLTL
                     QSCITNSVFMEDLGKLFYKDSQFHIHYNHQSGLKEVYRRALLESPSLQLMSALFFDDF
                     ASLDDLAEALFISLSTLKRLIRKTNLYLKEHFDIIISAKPIRVVGDEYNIRLFYIKYF
                     SEAYTFSEWPFASLLNENHHEQFVQLMASLIEVKIDFAIFRQLKLLSAVNLIRYLKGF
                     KIGKHKALSSLSLELLQDSQEMKKLSHLFVLKFSVPLDELVLSEMFSNYLDDDLVLEK
                     SLQVDKVKEEVPGPQSLLSWIDLLSEMEGATGIVLPNKYEVARYLHATVILGVEDISE
                     SFLIYDYKKDYLAFFKEHYTYVYFRFTDYVKRLFKDGDMELATNLLNNLVYSLLIAWE
                     NFFLTMCELMKKPKLLIIERSHGSTGSFLKKYIGEFFEITIFDKLTIEALCLQHDYDV
                     IITDTVIRGCEHADIFFFSRFVPTVIVAKLNHYLRKRMGSIFETKTTNKLGNIGY"
     gene            18019..18882
                     /locus_tag="TVB59_001353"
                     /pseudo
     CDS             18019..18882
                     /locus_tag="TVB59_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514825.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            19471..21972
                     /locus_tag="TVB59_001354"
     CDS             19471..21972
                     /locus_tag="TVB59_001354"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEL1010242.1"
                     /translation="MTFYNHKAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRFKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREINTTDPSYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLADLEEVDWPESIKD
                     MQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDSITTAEQ
                     AQAVAEYKRQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAIMAVPAHDERDWAFAKQFNLEIIPVLEGGNVDEAAYTEDGIHINSDFLDGLDKACA
                     IAKMVAWLEETGVGHEKVSYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPEQDLPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NDEQLADKDLLKQWLPVDIYIGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVDKRDGSFFHMETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGARKFLDRVYRLITTKEIVAENSGALD
                     KAYHETVKAVTEQIEGMKFNTAIAQLMIFVNAANKEDELYVAYAKGFVQLLAPFAPHL
                     GEELWQILTASGQSISYVAWPTHDDSKLVENDVEIVVQIKGKVKAKLVVAKDLSREEL
                     EKVALAHDKIQAEIAGKEVAKVIVVPNKLVNIVVK"
     gene            22159..22650
                     /locus_tag="TVB59_001355"
     CDS             22159..22650
                     /locus_tag="TVB59_001355"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010243.1"
                     /translation="MKKLVLASAAALVLAGATVSTGTVSANSSRYNYTGWNQGGYSWK
                     YLRLRNKNPYSRRTLTEDYSDQRKNEAKDSIKELSKLSDKEKKNFADRIDALTDTYAI
                     SSILSEAKNKNNDYLEFDKEYEALFNSNKYKLEIEKIKDRVYFDEGYSARQGINDLKS
                     LEN"
BASE COUNT         6669 a         4137 c         5041 g         6843 t
ORIGIN      
        1 tcaaggcttt tgcaggagat ttatgaaaaa gaaaaattta ggatagtgta agtataagct
       61 agtttcctta agaaaagctt aactgaagca attaatcgta gagatgggtg attgttttga
      121 cgactttttt ctccttgtca gaccaataat gaaggcgttc aaaagatcct tgtcgccagt
      181 agagtggtag cctttgtcga atatcctctt gcatgtctag cttatctaga tcagcaatag
      241 catgccattg tggtaggccc tctcgtgatt tagttagcag cttgccttca aaatcttcgc
      301 aaagaaagtc ataataaaca tagcgctcag gcttatcagg attggtaaag cctgagattc
      361 cctttaattg cagatttaag gcggttaagc cggtctcctc ctttagctca cgcactgccg
      421 cttcaaaaaa ggattctgag gtgttaacct tgccacccgg ttggatccag ccaggaaaat
      481 cgtcatgctg gcggttgaga agtaggatct tgtcgccctc cttgacacag atattaaccc
      541 aatttttgat gacttcaagc attagttacc tcgtttttag ttttatttta tcaaaaaaag
      601 atcagtatga atagctgaga gatttattga tatggtcata atggcttcag atagttttac
      661 tgctgcttta gccatctgca taaataatat aaaaatacca tttcacatca ttatttaata
      721 gatttattat catattaatg gtataattat gtgaaattag aactatgtgt agagagagta
      781 taatgaatag tacagatttg atgagactgg gagagcttta taaggagctt cgtattgctc
      841 gtggacttag gctaaaggac gttgctagag acaatttatc agtttcacag ctatctaagt
      901 ttgaaaatgg ccagagcatg ctggcagctg acaaactact attagctatt tcaggaatcc
      961 atatgacatt cgctgaattt ggtcatgctg taaatgggta taaagtcagc gatttttttc
     1021 agttaggcac caaggttgcc gagctacaaa cagcatcaga tatagatgga ttgaaggagc
     1081 ttctgagcca atataagggt gatgacattt tttctgttta taatagatta aatgaattaa
     1141 tcattaaaag tgctatctac tcacttgatc caaatgttaa aattgaagaa tcagacaagc
     1201 aattgttgac agaatacctt tatagtattg aagagtggac ggagtatgag ctatacattt
     1261 ttggcggttg tttggctatt ttatctgatg aggatatgat ttttttggga aaagcattta
     1321 tcgaacgaga taagattttc ctttctcttc cacaacatag aaaggcagct cacatcactc
     1381 tcttaaatat tatcatgaca aggcagcttt ttatgttgat ttttttatta aaaagctgga
     1441 ggagttgatt atctatcaag atatgttcac tatagtgagc ttaaattttt ttaagaaaat
     1501 atatacctac ttaaatgaag aaagtaagca taagagcgac attgaagatt atattaatct
     1561 tgttaaacag cttggcaacc ctcagtttgc ccaaattcta catcggacgc tatcagtgat
     1621 tctagatagt taatactaaa aaagtagccc aatcgtttgg tggctacagt ggccaaggcc
     1681 accaaataga caaaagggct aataagaaaa taaaagcttt tcgcataata tctcacctcc
     1741 ttgataagga tattatacaa aggggaagct tcaatctcaa acattcgcaa atatgaaaat
     1801 attaacaaaa gcatcatcat atttgcgaat atcgagaata tgataattgt cgtgatataa
     1861 ttactgtgtt aatgatttag ctaggcatta ataaatctaa atatagacta caggcaggtc
     1921 gctcgttata ctagtttgag ggccaatggt ctgggtagga ggaagcgtat ggcgacatta
     1981 gagcgacatc ataaaatgtt attattgtca atggcattag gggcagcgag ctggttagca
     2041 ctcggattga ttagcttgcc aaatcttgca ggtgctttag gaataagtac tgctaatgcc
     2101 aatactacag ttaatttgtt gagtgcttat agtacagttt ctagcgttgt tgcaatcgtt
     2161 ggtgctgtta cgggtgtagg gtctattgga gctggaattg cagctaccgt tttatacctt
     2221 atcaaacaaa aaggaaaggc tgctgctgct ctctggtagt taattgtctg atatgaagca
     2281 tgttttcaaa tatcataaag gcgacatttt agggtatctc aatattgttg ggtttaccct
     2341 tttgttttat ggctcagtga taggtatgat aatgttcagg gattatttga cctatgatgg
     2401 agctggttct ctaatatcga cctttattct ggtatcagga acctatcatt ctgtgaaatc
     2461 aacatttcca tatgaaggga agcgtcatcc aacttttata ttaacaccct attatctatt
     2521 taagcatcta ttgctttcag ttacaaaggt ttatgctttc cagatccgag tggttactat
     2581 aggaatcatc tgtttagcaa tagcctttcc ggagcagctt gtttggatag ccttgtctgt
     2641 gctagcagta tttatatatt ggctatcgct tccgctagta gccatttttc gagtagctgg
     2701 acgactcctg aatcttctca tgatttatgg tatgtatctt aatcaggagc tgctggtcat
     2761 tgcttgtctt tgtttaaatg tggttattct tgtgcttagt gttacgatta atgtacatta
     2821 tccctaccaa tggctggcgg tgagagctag gaaggaagaa aaaacaatta ccttgttaaa
     2881 gcttgttatc aatacgataa cagatcattt agctttaatg gttctgttta gtattttctg
     2941 tatagctgtg acctatttca cgcaaaggct gctgctaagt tttgattatt ctagctttag
     3001 cataccagtt tttttcttat ctgcttctac ctatatcgcg ttactagagg ttatggtcgg
     3061 taaaaatatt aaggagcttg agttagaccg gggcttggct gttttacagt ttctgaatag
     3121 ggatatcagt gtttacaaag cttatcgcaa cagccaattc ttgctttctg ctcacatctt
     3181 agctgttatt catacaggat gtgccatagg cttactacca tttttactaa atggtcaagc
     3241 tgctcttttt ctgtctaacc tagtgatgat ccccttcatc tactttatat cattttgcta
     3301 tttcgtgaaa tcactaaaaa tagttgctgg tgatttgtca gtgtttaggt gggttattct
     3361 ggttttgtat tttatactag tggtcattgc aatggtaggt agtcgtttat gataatgagg
     3421 aaatttttaa gatattatat cagttttatt attttctcaa tagcaattgg gattttaatc
     3481 ggtttgctga tcaccagtga tactgtcata ttatctaagc cagagcgggg ctgggatttt
     3541 actctggagg ttttgaagaa taatagcaat aattttttgt cctatatttt cctcttcttt
     3601 ttgtccccag ccttgcaatt gattgatttg gtatcagttg ttatacaaat tactctagga
     3661 atgaggaagt ctggatttct aataactgcc ttgggtttgt ttccgcatgg tttgctggag
     3721 atccctaatt ttctctttta tcaaggcttg agtcaatata tgctatggac tgttttgact
     3781 gaaaaaagca tgacgtcctt cttagaaaga gaaagaagat atgtaaggta ctatcttata
     3841 tcgtattatg ttttgttaat tgctggtatt atggaagggt tactcggatg aaaatagtaa
     3901 atgaaagcaa gtcattttca aacagaaaaa tcttaaatca catatccttt gactttagta
     3961 aagggctgta taaggttgaa gggaataatg gtagtggtaa aaccactttt ttgcgcttgt
     4021 tagcaggctt agaacggttt gatagcggcc atcgcttaca gcataaggga gatattctat
     4081 atcttgatac taatgctatc ggtgtagttc ccttaactat tgaagacaat ctgacattat
     4141 tatggaaaac ctttaatgcc tctcctgatg aggagacctt gtctgtgatt aatcagttct
     4201 ttggagaacg gttactagat cattatctga cggcttctgt aggaacaaag gctaaggtgg
     4261 gcttatcctt gctttttgta aaggattggg attatatttt catagacgaa gccctatcaa
     4321 cgcttgatgg gtttagtctt gatatggttg caggaagatt attagcatta aaagaaaagg
     4381 ctactgtttt ttacgtttct cataatctat cacaccagca gctattgtca gaatcacagg
     4441 tgatttatct taatggaaaa ggagaaatct attgaaaggt aatcctttta atcgtaatct
     4501 ttcttggtta atagcctatg tgctattact ttcttgttat gtattcatat tagtagatgg
     4561 tggtttttta aaaaacagcg ttcaagaatt ggaagtcctg ctcggccaaa catcactagc
     4621 tataaagctg tttttgatgg tgatatcaat agcttttagc atcatatctt tactggttga
     4681 gtatttttta agcaaatttt tagtgctgct ttttattgaa gctggcatcg tttctttaaa
     4741 tgatgttctt actgctaaat cagtgacttt agtgatccat ttatctgctt tgctattgaa
     4801 gctatctccc tctccacttt ttcagtttgt agtgaatgct ttagggattg tgatcatgta
     4861 tggattgagt atcaagagac aaggaaatag gacaactgct cttttgtttt gtttaccctt
     4921 tacactggat attctagcaa cattgttgct ttagtgattt tgagttggag gaaaagtaat
     4981 gaaaaaaatc ttatatttat cagtactttt aggaacgtca attctagcaa cattgattaa
     5041 aatttataac actttttttg caaagctaaa ggcttcatca ggtcattcaa ctgggaatat
     5101 agagattgat gcccttttat ctgagtctag actagtgttg gaaaggcagc atgccttcac
     5161 aacaaatgga atcaacaagc tattcgttat gatgatgagt ctaatgctgt tattagcctt
     5221 atactatctg ataaaaaagg atttgaaggc cgtctatagt tatttgcttt acctggtgtt
     5281 aaccttggtt catgcaattt atagcttctt ttcgttaagt cccttggcaa agctttattc
     5341 tgatgatatg ctgggggcta caatccagac gggagagaaa gctaaattga ttttttcagt
     5401 ggttcttttt cttctttatc tgcttattgt tgtggccaat aatagagtaa aatctagtgt
     5461 agaacccgct tcatctattg ggatagatgt gtaatacctt tcatattatg acctttaaag
     5521 ccttttagct tctctaattt tcagagtaac taggaggctg tttgtgacgc tctgagcgtt
     5581 ttttcgtttc tatcaaagtt tagctgcgtt aatgctatct atttccgtag ctgagataca
     5641 agatattata atatgtgttg tcataccata aaaacacctt acaggatatt ttatgatcaa
     5701 tcctccttga attaagcttt ctttaagcaa gggtgtgtat actagccgta atcctaaata
     5761 attggttacc taatgataac taattttttc ataacctcct tcctaaaaac gatgtcaggg
     5821 cagtcaggat tgattgctgt tatggcatcg tttttgttgt actttgatag gggatctagc
     5881 tgtatgttaa atagcctatc aggattgagt ggcgaagatg atcaggagtc tcttggctct
     5941 aggttatgct gctgtttcat gagaaacagc tcttgatgat caatttaggt agtattagtg
     6001 gtggtcatct tagcctttta ggctttgagc tgctttatgt ttgctcattt ttaatatgtt
     6061 agtgtttaca caaataattc tcattttttg atataataga aaaggtaagg aagggtagga
     6121 gataaggatg acaagatttt ttcaaaaaaa acaggccaaa agcttagcca ttggttttgt
     6181 gagcttgttt gctgtgctca ttgggtatgg agcttttcac tattctaagg ccagtcgtat
     6241 caatgcctat ctacaagcaa ggtcatcagg ctctgggcag gtgcttgaaa atatcaagga
     6301 atacctcgtg tgggcagata ccaatgagca gctgaccaat gatcaagcaa gatacaccag
     6361 ctttaagaga tacagtaagg cagagctagt aagcaagcgt cagcagctgc aaacagcaac
     6421 tgcagctgat gatatgtatg tcaaatcggt tggtcgcaaa tttttgattt tccctgatta
     6481 tcgcatagca gtgaagcctg tagccttgac aatcaagacc aatgtgccaa atgttgatat
     6541 cttgttgaac cataaaaaga ttgctgtatc acagtcagag gattttagca caactattga
     6601 aagactgccg gctgctgatt ataaggcgag tattaatggc tattataagg atcgtaagat
     6661 taaagtcagc aaggcctatg atggcaagaa ccatacacta gatttgaggg ttacctttaa
     6721 gacatttacg gtaaccagca atgtcagaga tggcgagctt tatattgatg gcgagcgcgt
     6781 ggaaactttg aaggctgggc agcttcagct ggaagaatac cctgtgacag aaatcgcaaa
     6841 ggcctatatt aaaaagacct ttcctgatgg cgagctaacc tccagcaagc attcccttgc
     6901 tcctgttgct gagggctccc agctagagat taacattgat cacctcttga ctgaggaaca
     6961 ggcgggacag gtgttggtgg cagcctttga tcaattgctc acctatctca atcaagggca
     7021 ggatccagca ggtctttcaa ctgtttttga gcaaggggct aataatgctt tttacaaagg
     7081 cttgaaggat tccatcaaag caaaatttca aactgatacc agaaaggctt ctcggttaag
     7141 cattccgtct attttgttaa gtaagctaac tcaaattggt aagcagtctt atctagtgga
     7201 ctttacagct gtttatgatt ttgtttacga taaggaaact gatcctgaaa aaggcacctc
     7261 agggaatgtt cgtcaagact tgactggtaa gctgaccctg aaaaaatctg gggatagcta
     7321 ccttgttagt cagtctggtc ctaaaaatat tacagttgcc agcgaaaaaa atcaggtcaa
     7381 gccgtctatt ttcccagagg ggctagtggg aacctggata ggacatcgtt cggacatgac
     7441 ctttacgatg atattggcta aggacggcag catcacaaca accattggaa acaaaaatgg
     7501 gaatggctca cagaccacta agtctgctaa aattaccaag gtagaggaaa aaggagatgg
     7561 cttgttcctc tacactgtag ctccagatgc tgatatagca gctcttgttc caggaggtgg
     7621 attgggtggt gtcaatgtca aatacgcttt tggtgtcaaa tggagtggag atgtcgctac
     7681 gatagtggtt tggcagacag caaataatgc ggcatttgat tacagtaagc caatgcttgg
     7741 ccctgacatg aaaaagcaat aagtacttta ccctacaagt tggtctagca tttattgcta
     7801 ggaggaatca gcataaagaa aaagcctctc ttttaatctt ttgtggttaa gaagagaggc
     7861 tttttagtat agggctgact gtatgaggag caaccgatgt aatcaattta gctgctgtag
     7921 tccttcttta aagcttttag acggggcagt gaccctaatc atctcttgag ccaaggggtg
     7981 tctaagggtt agctgatgag cgtgcagcat gagacgctcc gctttttgcc tgctatagag
     8041 gggatcacca attagagggt gtttatgatg agcgagatgt actctgattt gatgtgttcg
     8101 tcctgtctct aggcgacagt tgactaggca ggtctgatca aaggcttgta ataaggctag
     8161 atgggtgatt gcctcttgcc catgcttact atcaaccaca cgcttgcgcc tatcgtggcg
     8221 gtgacgtccg attggatcgc gataggttac tgtttgctgc tctagctgac cttcgattag
     8281 ggcccaataa tctcgcttaa tgtctcgatg ctccaatagg cgatttaaga tcggaaggat
     8341 aaagggattt ttagcaaaga gaatcgctcc actagtctcc atgtctaagc gatgaaccac
     8401 atagcaggtc ttgccagtat aggcagagac atggttgagc aaggcgagct cagtgggctc
     8461 attgccatgt gttttcatgc cctcgggctt gttgacaatg atgaggtgtt cgtcctgata
     8521 caggcaatcc actaggccag gcttacccat taagatgcct ttatcagggt agtcttcttg
     8581 gtcaaattgt agcttgatgt gatcaccctg cttgacaggg ctctgccagt taatcagctc
     8641 atcattgacc caaacatgct ttttgatgcg caagaaatgt ctgattttac ggggaatcaa
     8701 tagcctatct tctaataact ccttgacagt tgtcgcttga taggggttaa tgaaggagat
     8761 ctgaaagccc atctcaggct tatttgctgt tgtcattgag ccagtcatgg tatttttcaa
     8821 tcaaattgat ggccatttgg gttgcaagag ttacagagaa agcctcggtt ccctcgcgct
     8881 cgtcactggc aacctctaag cgtgtctcat catagacagc cttgaggctc tctgctgaca
     8941 gggtttcttt aaaagcttga aatttgttca tgatcatgtc ctacctttct aaatgtttgt
     9001 gacaatgcta ttatagcata tttttcatca aagctaatca tttgctcgat gatttgtgct
     9061 gcgctaacag cgtgattctt ttgagaaaaa ataagattag ctattgtgaa attgtctgtc
     9121 ttttattata ctaagaatag tctgataaat atattattta aggacacgat aacattggga
     9181 ttatgaatca tttaggagaa tactattgaa caagccattg ataaaatcct gtttgcttgc
     9241 tctattgacc ttggccggct tgaccagtat ggcagcacag gctgatgtca acacttacaa
     9301 ccaaggtagg acatataacg atacacccta ttattctgct tatcatcact actatgacca
     9361 cacgagggat actgctgaca atggtattga taattggggt cgtctgacac gctatcacta
     9421 ttacagagag acctattatc agcttgaggc cgagcgtcag cagcttgtta ggacttactt
     9481 ggagttgaag gcttcatatg atgatcaggt ggctcttagc agtcaacgac tacagcagta
     9541 ccagtctggc tggtctgatc tccaatcacg ctttgagcag ctcaggaaaa ccaatcctgt
     9601 tgtaggcggt gattatcgga ttgttgagct agagggcaat tttcaaagct atcagacctt
     9661 gctgcagcag ctttctatgg ctgattttgt cagccagtac aaagataggc tggatacctt
     9721 gactagactt gatacagagc gagctaggct cattgacacc tggtgggaaa gtgatagcaa
     9781 ttactcagat ctcaatacca atctaacact agtcaatggc tatatcaagg agctgaatca
     9841 ggctttacag gagcttctta aggaccatca aggtaaaatg acatcagatc tgcagacctt
     9901 gggtgaccga caggccgagc ttgctagacg gctgacagat atagaaagca ggcctaagag
     9961 acaggctacc agtcaacctc gtggttcaca gacacattgg cgatcagccc ctagagctga
    10021 tgttgccttg tggaatgaat tgcgaaacga aggagattat gcttctgcta cgacagacaa
    10081 tgctttgcca ttgcagcctt atcgagcgga cttaacagct gttcatgatc tagaagcctt
    10141 gcaagcacaa tctgatagag cacaccgctt gcgggcaaag gaaattgtct ttacactgca
    10201 gcgttctaac attagtcgtc agggcgatat agatttgtca ggagccatta cagcatttat
    10261 caaagaaaag cttctcgtca ctccaaatgc gcgtggggta tcatctggct ttaggtggca
    10321 aatgcaaacc tatgacaatg agcgcttaac catcactcta atgcctcaat attatatgac
    10381 tgatgatcag tacaaggagt attacgacca tctcaaggct tggacagctc agcatatcca
    10441 gtctaccgat acagaggttg agaaaattga taagattcaa gactatatca tgacaaacta
    10501 ccactatgcg accggcaagg ttggaggagt gacccgtact ggcatttctg tgcagacgcc
    10561 atatgccttt atcaaggaca aggaggctgt ttgtcaggcc tatgcacaga tgtttaagga
    10621 catgggacga ctagctggac ttgatgttca ttatattcaa ggctatggag acccagttgg
    10681 cggcttatca agtctacatg cttggaatat cgtcaaggtt gatggtcaat attatcatat
    10741 tgacctgact tggaatgata ctattgacag caccaatcac aatcatacct acaccctgcg
    10801 aggcaatgat tttatgagca aaacacattt gtggaatgct gcctatgcga tctcagatag
    10861 tgactatgct gcttatccta ggaggagctt cctgagatat gggacctatg cgactaacta
    10921 ttcaagaaat acattttatc caggatacag ttatgcttaa taatagctaa taccatcaaa
    10981 agccctagaa agcttgcttg attctttcag ggctttttga tatgtcatgg tttttggtat
    11041 aggattttga aagaaattgt tataatagga taaaatgctt atgtaacagg agaaaataaa
    11101 atgaagagta ttagacgcta tgatgtcaat gaagagtggg cacatactgg cttagtagag
    11161 gcaggcgatt tttatttttt aaattattgt gtaggaaatg tcggtcaaga tattgaggct
    11221 caaattaacg gtgcctttga tgaaatggag cgtcgtttgg ggctggtagg gctgacgcta
    11281 gaggtcgttg ttcaaatgga ttgcttgttt agagacattt ggaatgtgcc agttatggaa
    11341 aaaatcatca aggagcgatt taatggcaaa tacccggctc gtaaatttct tcaaacagcc
    11401 tttgctcatc agggtggtcc ggacggcttg ctatttcagg tagatggggt tgcttattca
    11461 aagcatatct ccgtatccta aacaatatga cttggaggct tagtagtatc ataaggctat
    11521 gacattttta gaattattac aaaagaaatt ttttccaaaa aaataccaag aaaaacaggc
    11581 cttaaaggaa agggcagccc agcatatggc tgacaaagag gctactactc aggctactgc
    11641 cactgctttg gccgatcagg aggcacaggc agggcagact gagaggcaat cagtccttca
    11701 acgcagcaag tcctatgggg tcaaaaggaa aaatcggccg atctggcttc aaaggctgga
    11761 ggcgattttg ccatcgcagc aaggtcctat tcgccgcttt cttcgtcgtt accatgttgg
    11821 taaaatcctg ctgattttga tgggtacctt tgtcttgctg ctggggtctt acctttttta
    11881 cctttcaaag acagctaagg tttctgactt gcaggacgct cttaaggcga cgacagtcat
    11941 ctatgaccgc aagggagaat atgcaggcag tctttctggt caaaagggga cctatgtgga
    12001 gcttgacgct atttcagatg atttggaaaa ggcggttatt gccacagagg accgtacctt
    12061 ttataccaac aatggtatta atttcaagcg ctttttattg gctattgtga ccgcaggacg
    12121 ctttggtgga ggctcgacca ttactcagca gttggctaaa aatgcttatt tgtcccagga
    12181 gcagagcatt aaaagaaagg cgcgtgagtt tttcttagca cttgaattga ccaagaaata
    12241 cagtaaaaat gacattttga ccatgtatct caataattcc tattttggaa atggtatttg
    12301 gggtgttgag gacgccagtc aaaaatattt tggtacctca gcagctaatc taaccttgga
    12361 cgaggcagca acccttgccg gtatgctcaa gggacctgaa atttacaatc cctattactc
    12421 aatcgaaaag gcaaccaacc gtagagatac tgttttgtca gccatggttg acgctggaaa
    12481 aatcagcaag cagcaggcac aagaggccca agctattggt atggggaacc gtttagcaga
    12541 cacctatgtc ggcaagacag atgattatca gtacccatct tattttgatg ctgttatcaa
    12601 tgaggctatc tcgcgctatg gcatctcaga aaaggatatt gtcaatgatg gctacaagat
    12661 ttacacagag ttggaccaaa attaccaagc aggcatgcag accaccttta atgaggatag
    12721 cctatttcct gtgtctgagt ttgacggcag ctcagctgag gcggctagtg tggctctaga
    12781 tcctaaaacc ggagctgtca gggggcttgt tggtcgtgtc aatagcacag aaaaccagcc
    12841 ctttagaagc tttaactatg ctactcaagc caagcgtagc cctgcttcaa cgatcaagcc
    12901 cctagttgtt tatactcctg ctgttgcagc aggctggtca ctggagcacg aactgccaaa
    12961 cagcgttcag gattttggcg gttatcagcc gcataattat ggcaattacg aatcagaaac
    13021 aattcctatg tatcaggctt tggctaattc ctacaatatt cctgctgttt caattctgga
    13081 tcagttgggg gtggataagg cctttagcta tggtgaaaaa tttggtttga agatgagtga
    13141 aaccaaaaag gagcttggag tggcgcttgg tagtggtgtc accaccaatc cgcttgagat
    13201 ggcacaggcc tatgcagtct ttgccaatgg tggtgtcaag catattgccc acctgattac
    13261 cagaattgaa aatgctaagg gcaaggttat caagaccttt acagacaaaa ccaagcgggt
    13321 tatcagtcaa tcagtggctg ataagatgac tagcatgatg cttggaacct tttctaatgg
    13381 tacagctgtt aatgccaatg tctatggcta tactctggct ggtaaaacag ggaccacaga
    13441 aactgacttt aacccggacc tttccggtga tcagtgggtc attggctaca cgccagacgt
    13501 tgttatcagt caatgggttg gcttcaatca aaccgatgag catcattatt tatcagattc
    13561 aagtgcgggc actgcctcag caatttttag cacccaagcc tcttatatat tgccatatac
    13621 caaaggaagc caattcaagg tcgataacgc ttacgctcaa aacggtattt cagcggttta
    13681 tgggattaat gagaccaata cgcaagcagg tattgattct caatccatca ttgatagtct
    13741 tagaaagtca gccgaggaag cttcaaagtc tatttcagag gcagttgatc aatctggtct
    13801 cagagaaaag gcgcaaagta tctggaagag tattgttgac tactttagat agcttgcgaa
    13861 aatatctaaa tcgtgttaga ataatcacta cggaggcgtt atggcacaga aaaaagcaag
    13921 cctagcgtgt gtagaatgtg gcagccgcaa ttattctatc gggattagta gcacgcctag
    13981 accaacacga ctagaagtca ataagttttg caaatattgt aaagcataca ccttacacaa
    14041 agaaacacgt tagaggagag cctgatggga ttcattagtg ggatttttaa gcttttaagg
    14101 gatacaactt ggccggatcg taagcagcgc tggaaggact ttatttctgt ccttgagtat
    14161 acagcattct ttacggtaat catctttatc tttgaccagt tgctatcaaa aggcatttta
    14221 tcattgatta atttattcta agtcattgca atgatgagac ctgttatgat taaaattgct
    14281 tggaaaagcc taggctgaaa caatcgtttc ggcctttttg agtgcgatgg gcaggttgta
    14341 ctctgataga tgcaagacca atagaccacc tactatgcgg gtgcgtaaag gggttgatag
    14401 ctaccgatag ttaagggcta tagcaagtag aaaggcttgc agctcagctg atccgctgtt
    14461 atgactaaag gcattgacca gaaaggttcg ttggcagcca acaaagtgct cttaccctgc
    14521 tatgaggggc tattaatgcg ttgacagcca atccttcttc tattataatg aaagtgtgat
    14581 aacagcaatg caaaggccag cagaggcttt tttataatga aaggaagtaa catgttagat
    14641 tcttttgata agggctggtt tgtccttcaa acttactcag gctatgaaaa taaagtaaaa
    14701 gaaaaccttt tgcagcgtgc tcaaacctat aacatgctag acaatattct ccgcgttgag
    14761 attcctaccc aaacggtaaa tgttgaaaaa aatggtcagg tcaaagaggt tgaggaaaac
    14821 cgcttcccag gatatgtttt ggttgagatg gttatgactg atgacgcttg gtttgttgtt
    14881 cgtaacacac caaatgtgac aggctttgtc ggatcgcatg ggaaccgctc aaaaccaacc
    14941 cctctacttg aagaggagat tcgtgctatc ctgttgtcaa tgggacaaac tgttgatgtc
    15001 tttgatacca acattaaaga gggcgatatg gttcaaatca ttgatggcgc ctttatcggg
    15061 caagagggtc gtgtcgtaga aattgaaaac aacaaggtca agctcatgct taatatgttt
    15121 ggctcagaaa ccttagcaga ggtcgagctt taccaaatcg cagagctatc gtcctgatag
    15181 gctcctaaag ctattattca taccataaaa aataaaaggc tggcatcggc tctctaaaat
    15241 accgatgtta ggcctttttt gttggtcttc tacaaccaag actcaaatta accaaaccct
    15301 aaaaagagtc atttttcctt cgctttttaa gtctctaact gatcgcccta gcttattttt
    15361 aatctagtaa tcgcaacagg tcaagagtta aatgatatcg cgccgttatt gattggtata
    15421 gacaaaaata cgctcaaaaa aagaaaaaag gataggtaat atagtcctgg tttgcttgat
    15481 agatggtggt tggcaaccaa ccattcgagt actttcctta actataaact cctaatcaat
    15541 tctagcgttt aaaaaataag attattcttg gagggaagca aagagcttct ctcctttttg
    15601 agttgtagca ttcttgatcc tgatcttata agcagagtcc tgtttgccgg gctgttgaga
    15661 tgaataaggg catttctata gtgattatat agtgttgcag atgtgtgtat ggtttaaggt
    15721 ctaaataccc ttcaagctta gttcttgggt agtcagttcg gattggctgg ctgattttta
    15781 agcctttaat ggcttagtgg taagacaaac cagattacat ttgctaaaaa gtccctaagg
    15841 ctacaatcat tttttgtgac taatataaaa actagacctt ttgggatttg taataattta
    15901 gattattgtt tttaaaatta gcaaatatta aacgcttttt tattgaagat acagatgata
    15961 gtaatggcag agctaaaaaa taagagaaaa taaaaaaagt ctacaattta taatgtaata
    16021 aaaaaatgag ttgactgttg tgttttaaag gcttttgtct atttgtaatc ggttaatttg
    16081 caaacaattc taaggtattt ctggctaata gtatgctata atgtaatact gttctacaac
    16141 cgacattaag agttaatgaa atagtgttgt gttgtggtaa gtttttaatc aggaagagta
    16201 tatttaggag ctagatacca tgtctataga gaatctcttt accaagcagc agtggcgaga
    16261 gcttgagttg attactttat taagtgaaac gaaaaatcca ttatattata aagatgcttg
    16321 tcagatgctg gattgttcgg ttttaacgct gcaatcgtgt atcacgaatt ctgtttttat
    16381 ggaagattta ggcaagctgt tctacaagga ttctcaattt catattcatt acaatcatca
    16441 aagtggctta aaggaggttt atcggagagc cttgctagag tctccttctc ttcagttgat
    16501 gtcggccttg ttttttgatg attttgcgtc attagatgat cttgcagagg cactttttat
    16561 tagcttgtca accttaaagc gcttgattcg taaaaccaat ctctatttaa aagagcattt
    16621 tgatattatc atttcggcta agcccattcg tgtagttgga gatgaataca atattagact
    16681 gttttacatc aagtattttt cagaagcata taccttttct gaatggcctt ttgcttctct
    16741 acttaatgaa aaccaccatg agcaatttgt tcaattaatg gcatctttga tagaggttaa
    16801 gattgatttt gcgatttttc gtcaactcaa gctattaagt gcggttaatc tcattcgcta
    16861 cctcaaaggc tttaaaattg ggaagcataa agcactgagt agtctttcat tggagttgtt
    16921 acaggattct caggagatga aaaagctgtc gcatttgttt gtgcttaaat tttcagtacc
    16981 gcttgatgag cttgtcttgt cagaaatgtt ttccaattat ttagatgatg atttggtatt
    17041 agaaaaatcc ttgcaggtag ataaggttaa ggaggaggtt ccgggtcctc agtccttgct
    17101 gagctggata gatttgctta gtgaaatgga gggagctaca ggtattgtat tgccaaataa
    17161 atatgaggtt gccagatatc ttcatgccac tgttatttta ggagtggagg atattagtga
    17221 aagctttctg atttacgatt ataaaaagga ttacttggcc ttctttaagg agcattatac
    17281 ctatgtttat tttaggttta ccgattatgt gaagaggcta tttaaggacg gggatatgga
    17341 gcttgctact aatttgctca acaatttggt ttattccttg ctgatagcct gggagaattt
    17401 ctttttaacc atgtgtgaat tgatgaaaaa accaaagctc ttgattatag aaagaagtca
    17461 tggcagtacg ggaagctttt tgaaaaaata cattggtgaa ttttttgaga ttaccatttt
    17521 tgataaatta accatagaag ccttgtgtct acagcatgac tatgacgtca ttattactga
    17581 tacggtcatt aggggctgtg agcatgctga tatctttttc tttagtcgat ttgtgccaac
    17641 cgttatagtc gccaagctta accattatct aagaaaacga atgggtagta tctttgaaac
    17701 gaaaacaact aacaagcttg ggaacatcgg ctattgatag atatcggtat atttcattaa
    17761 aatagccaca acttgtcatg gtgtaaaatt agtgagcttt gttaatccaa taaaattagg
    17821 tagaatatag ctataggcca acgtgtaatt cccttaggga gtaggtgctt tggtctggga
    17881 aagagaaaaa taaaaaggag aaacaaacaa catgaagagt tgtaaatcaa ccctagttta
    17941 gataaaaaga ttaattcttc tattggtatc aaaggaagta attttatttc ctcaaaactt
    18001 ttagcgaatt taaagactcg catcgactct gaagctactt tgaaagcaga aacaactcaa
    18061 ttgaaagccg atatagaaag agaaaaactt acttctaaag aattaagcac taaactggaa
    18121 gaggtaacat cagatcgtga taatgctctc agtgaatctg ccgatcttgc caacaaactc
    18181 tcagtagctc aagcagaagc agatcgttta agtcaggctg ttgatagtct gggtcgattg
    18241 actaactctg ctaagcgtga gctcacagag aagcttgctg agattgatca attaacacag
    18301 gacaaggtta aagcagagac tgaccttgaa actgctaatg ctaacatcac aacacttcaa
    18361 gaggagctgg caggtgctaa ggctaatgtt gataagcttg caaaggaaaa agctgcggca
    18421 gatcaggcac ttgctgaagc taatgcaaga gtatcaaatc ttgggcaaga ggtagcagca
    18481 gctaataata gagtggctga ccttgaagcg caattagctg aaaaaacagc cgagcttgat
    18541 gtggttaagg cagacaaggc agagcttgag gctaaggtta aggagcttca aagcctgctt
    18601 gagcaaaagg atcgtagcaa tgctgatctt caagctaaca ttgagcgctt gaagcaggag
    18661 cttgctgaca agtttaagga tcaggcacag cctcgttcta agactcctca ggcatcgaac
    18721 tcggttgcaa agcaaaaagc aagtaagcca gccgcaaaac cagcaggcca gctaccatca
    18781 acaggtgaag ctactgcaaa tccatttttc actgctgctg cagttgcgat tatgacaagt
    18841 gcaggcctag taacagtcat gccaaaacgc caaaaaaatt aagctattct caattctctc
    18901 ccctttaact attgttttat agcattttac taatggacat tggcattcct ataaactcta
    18961 ttgagcttct tatctgatag caaggataag gggcttttta gtagcttagc aagcactcct
    19021 tggtcaagct caatacctct ttgagagctt aaaactagag ctagaccaga tctaaaacca
    19081 agtgagatga tagcggatat ttggctgttt tatgagttgg ctcgtaaggc ttgagcttat
    19141 gcgtcgcaga gacgcgctat ctagtctaaa gggctttagc aatgtcgtga caaacgcatg
    19201 aagacagtta cactttctca tagcgagttt ttatcatcag tatagttttt ttggcaatat
    19261 gttatgaaat agtcaaatag caatcgagaa actggtgata ttgcaatgca aaaccgctga
    19321 acatagatta aaaaaatgca tgcagctaga aaatggttac atgcattttt gtgatgccga
    19381 cgtcgtggca gcaatattgc ttgcccattc ctaaaagtct gatatcgtgc tataataaga
    19441 agactagact ttttacatgg gagaattcac atgacatttt acaatcacaa agccattgag
    19501 cctaagtggc aggccttttg ggctgataat cataccttta aaacggggac agatgcctca
    19561 aagcctaaat tttatgcttt agatatgttt ccttatcctt ccggtgcagg tcttcatgtt
    19621 gggcatcctg agggttacac tgcaactgat attttaagcc gcttcaagcg tgcacagggt
    19681 tataatgtcc tccacccaat gggctgggat gcctttggtc tgcctgctga gcaatacgcg
    19741 atggatactg gtaatgaccc tgctgagttt acagcagaaa acattgccaa ctttaaacgt
    19801 cagatcaatg ctcttggctt ctcgtatgac tgggatcgtg agatcaatac aactgatcct
    19861 agttactaca aatggacaca gtggattttc acaaaattgt atgaaaaagg cctagcctat
    19921 gaagctgagg tgcctgttaa ctgggttgaa gagctgggaa cagctattgc gaatgaggag
    19981 gttctccctg atggcacatc agagcgtgga ggctatccag ttgtccgtaa gcccatgcgc
    20041 caatggatgc tcaaaatcac agcctacgca gagcgcttgc tagcagatct ggaggaagtg
    20101 gattggccag agtcgatcaa ggatatgcag cgcaactgga ttggtaaatc aacaggggct
    20161 aatgtaacct tcaaggtcaa agataccgat aaagacttca ccgtctttac cacacgacct
    20221 gataccctgt ttggtgcaac ctatgctgtt ttggcaccag aacacgcctt agtagatagc
    20281 attactacag cagagcaagc gcaggctgtt gctgagtaca aacgccaagc gagcctcaaa
    20341 tctgaccttg ctcgtaccga tcttgccaag gaaaaaacag gtgtctggac aggagcctat
    20401 gcgatcaacc cggtcaatgg caaagaaatg cctatctgga ttgcggatta tgtgcttgca
    20461 agctacggta caggtgctat catggcagtg ccagcgcatg atgagcgtga ctgggcattt
    20521 gcaaagcaat tcaatcttga gattattcca gtgcttgaag ggggcaatgt tgatgaggct
    20581 gcctacacag aggacggtat tcacattaat tctgacttcc tagatggtct tgataaggct
    20641 tgtgccattg ctaaaatggt ggcgtggctg gaggagactg gtgtcggtca tgaaaaggtc
    20701 tcttatcgcc tacgtgactg gctgttcagt cgtcagcgct actggggtga gccaatccca
    20761 atcattcatt gggaggacgg tacctcgaca gcggttcctg agcaggacct accacttgtt
    20821 ttgccagtga ccaaggatat tcgcccatct ggtacaggag aatcaccact agctaacttg
    20881 actgactggc ttgaggtgac ccgcgaggat ggggtcaaag ggcgtcgtga gaccaacacc
    20941 atgccacagt gggctggctc aagctggtat taccttcgct atattgaccc acacaatgat
    21001 gagcaattag ctgataagga cctgttaaag caatggctgc cagtagatat ttacattggt
    21061 ggtgctgagc acgcagtgct tcatctgctt tatgcacgct tctggcacaa ggtactctat
    21121 gatctgggtg tagtgccaac caaggagccc ttccaaaagc tctttaatca aggcatgatt
    21181 ttgggaacca gctatcgcga ccatcgtggg gccttggtcg caacggataa ggttgacaag
    21241 cgtgatggta gcttcttcca catggaaaca ggcgaggagc ttgagcaggc ccctgctaag
    21301 atgtctaaat cactgaaaaa cgttgtcaac ccagacgatg tggtggagca gtacggagca
    21361 gataccctgc gtgtgtatga aatgtttatg gggccacttg atgcgtccat tgcttggtct
    21421 gaagaaggcc ttgagggagc acgcaagttc ctagatcgtg tttaccgttt gatcacgaca
    21481 aaggaaattg ttgcagaaaa tagcggagct ttagataagg cttaccatga gactgttaag
    21541 gcagtcacag aacaaatcga aggcatgaaa ttcaatactg ctattgccca gctcatgatt
    21601 tttgtcaatg cagccaataa agaggacgag ctttatgtgg catacgccaa aggcttcgtt
    21661 caattgctag ccccatttgc cccacaccta ggtgaagaat tatggcagat cctgacagct
    21721 tcaggtcaat ccatctcgta tgttgcatgg ccaacccatg acgatagtaa gctcgttgaa
    21781 aatgatgttg aaatcgttgt tcaaattaaa ggaaaggtca aggctaagct tgtcgtggca
    21841 aaagacctct caagagaaga gctagaaaaa gtagccctag cacatgataa aatacaggct
    21901 gaaattgcag gcaaggaagt ggcaaaggtc atcgttgttc ctaataagct cgttaatatt
    21961 gtggtgaaat aaagacccta gcaaaaaatg ccttccttat aattttgagc ccaatactat
    22021 aaaaagctga taaccactcg tttacatgag tggttattct tgttttgtaa cacgctatta
    22081 aaactgatat tgaagaagct tgaagataat agtaaaataa aaccctaaac ttatttaata
    22141 aatggaggat ttttcaacgt gaaaaaatta gttttagcca gtgcagcagc acttgtatta
    22201 gcaggagcaa ctgtaagtac aggaacagta agtgcgaata gttcaagata taattatacc
    22261 ggttggaatc aaggtgggta ctcatggaaa tatttgcgcc taagaaataa aaatccttat
    22321 tcacgtcgta cccttacaga agactattct gatcaaagaa agaatgaagc aaaagatagt
    22381 attaaagaat tgagtaagct tagtgataaa gagaaaaaga attttgctga tagaattgat
    22441 gctttgactg acacctatgc aatcagctct attctatcag aagctaaaaa taagaataat
    22501 gactatttag aatttgataa agaatatgag gctttattca attcaaataa gtataagtta
    22561 gaaatagaga aaataaagga tcgtgtgtac tttgatgaag gttactcagc tagacaaggg
    22621 attaatgact tgaaaagtct ggagaattaa acagtagaca gatttattat ttatcaaaat
    22681 aatccaactg
//
LOCUS       DARYNN010000035        22607 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.035, whole genome shotgun sequence.
ACCESSION   DARYNN010000035 DARYNN010000000
VERSION     DARYNN010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22607)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22607)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22607
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.035"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            414..1898
                     /locus_tag="TVB59_001356"
     CDS             414..1898
                     /locus_tag="TVB59_001356"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004229889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEL1010244.1"
                     /translation="MPMMYQSTRNAANKVTASQAILSGLADDGGLFTPTSMPVLDLDF
                     EELKTKSYQEVAKLILSAFFDDYTEAELDACISSAYDDKFDTAVIAPLATLKDYHNLE
                     LFHGSTIAFKDMALSILPYLLTTAAKKQGVERKIAILTATSGDTGKAAMAGFVDVPGT
                     DIIVFYPKSGVSRIQELQMITQAGHNTHVVAIEGNFDDAQTEVKRLFNDPDLRERLAA
                     QQIQLSSANSMNIGRLIPQVVYYIYAYAQLVRHQRLEAGETINIVVPTGNFGNLLVAY
                     YAKEIGLPVAKFICASNENNVLTDFFASGRYDKKRPFKVTTSPSMDILVSSNLERLVF
                     YLLGNDAQKTAVLMKSLAETGQYQLADADQSILDLFAAGFATEQETAKEIKTIFESDH
                     YVLDPHTAVASAVYRAYREQSGDSRPTIVASTASPYKFPRVVVEAISGQQVASDFEAL
                     EQLADISGVVVPQAVNGLQEAPIRHSLLVTVADMQQAVEAYLGV"
     gene            1938..3239
                     /locus_tag="TVB59_001357"
     CDS             1938..3239
                     /locus_tag="TVB59_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEL1010245.1"
                     /translation="MTHNRKKILSLALPSMAENILQMLMGMIDNYLAAQIGLTAVSGI
                     AIANNILTIYQALFIALGAAVSSLIARSVGEQNHSKEIDYMANAILVTGALSVLLGLM
                     SVVGHKSILAFLGAASLVARLGGQYLAIVGGMILSLGLFTSLGAIIRAKGQPSIPMKV
                     SLLTNLLNAVFSALSLYIWGFGVIGIAWSTVASRLIGVVILCHFLPIKEIIKRFANPL
                     DKEIFSLSLPAAGERLMMRAGDVLIVTIIVRFGTEALAGNAIGETLTQFNYMPGLAMS
                     TATVILVANQLGSGKGATIAKTVKETFLLATLMMLVMGLITYLLGPNLLPLFTADAKA
                     QQAGMVVLVFSLLGVPATAGTLVYTAAWQGIGQAKLPFYATTIGMWLVRISLGYFIGV
                     TLNYGVIGVWLATILDNATRWLILAVAFKKQQRQLFSDCHS"
     gene            3619..3927
                     /gene="rpsJ"
                     /locus_tag="TVB59_001358"
     CDS             3619..3927
                     /gene="rpsJ"
                     /locus_tag="TVB59_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEL1010246.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAEKIVETATRTGATVAGPVPLPT
                     ERSLYTIIRATHNYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            4225..4851
                     /gene="rplC"
                     /locus_tag="TVB59_001359"
     CDS             4225..4851
                     /gene="rplC"
                     /locus_tag="TVB59_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEL1010247.1"
                     /translation="MTKGILGEKVGMTQIFTESGEFIPVTVIEATPNVVLQVKTVETD
                     GYEAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNIEGLEVGAEITVDIFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVSPNRVFKNKHLAG
                     RMGGNRVTIQNLEIVQVIPEKNVILIKGNVPGAKKSLITIKSAVKAAK"
     gene            4876..5499
                     /gene="rplD"
                     /locus_tag="TVB59_001360"
     CDS             4876..5499
                     /gene="rplD"
                     /locus_tag="TVB59_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEL1010248.1"
                     /translation="MANVKLFDQTGKEVSTVELNDDIFGIEPNESVVFDVVISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSAKVAEDKFVAVESLSFAAPKTAEFAKVLSALSIDTKVLVLVEEGN
                     EFAALSARNLPNVAVATAATASVLDIVNADKLLVTKEAISTIEEVLA"
     gene            5499..5795
                     /locus_tag="TVB59_001361"
     CDS             5499..5795
                     /locus_tag="TVB59_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEL1010249.1"
                     /translation="MNLYDVIKKPVITEKSMYALEEGKYTFEVDTRAHKLLIKQAVEA
                     AFDGVKVASVNTVNVKPKAKRVGRYTGFTSKTKKAIITLTADSKAIELFAVEAE"
     gene            5813..6646
                     /gene="rplB"
                     /locus_tag="TVB59_001362"
     CDS             5813..6646
                     /gene="rplB"
                     /locus_tag="TVB59_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEL1010250.1"
                     /translation="MGIKVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVSLKNKAGRN
                     NNGRITVRHQGGGHKRHYRLIDFKRNKDGVEAVVKTIEYDPNRTANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPDADIKVGNALPLVNIPVGTVVHNIELKPGKGGELVRAAGA
                     SAQVLGQEGKYVLVRLQSGEVRMILGTCRATVGTVGNEQQSLVNIGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSNKLLVRRRNE
                     K"
     gene            6758..7036
                     /gene="rpsS"
                     /locus_tag="TVB59_001363"
     CDS             6758..7036
                     /gene="rpsS"
                     /locus_tag="TVB59_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEL1010251.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRR"
     gene            7052..7396
                     /gene="rplV"
                     /locus_tag="TVB59_001364"
     CDS             7052..7396
                     /gene="rplV"
                     /locus_tag="TVB59_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEL1010252.1"
                     /translation="MAEITSAKAMARTVRVSPRKTRLVLDLIRGKKVADAIAILKFTP
                     NKAARVIEKTLNSAIANAENNFGLEKANLVVSETFANEGPTMKRFRPRAKGSASPINK
                     RTTHVTVVVSEK"
     gene            7409..8062
                     /gene="rpsC"
                     /locus_tag="TVB59_001365"
     CDS             7409..8062
                     /gene="rpsC"
                     /locus_tag="TVB59_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEL1010253.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFINK
                     ELAEASVSTIEIERAVNKVIVSLHTAKPGMVIGKGGANVDALRAQLNKLTGKQVHINI
                     IEIKQPDLDAHLVGENIARQLEQRVAFRRAQKQAIQRTMRAGAKGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            8066..8479
                     /gene="rplP"
                     /locus_tag="TVB59_001366"
     CDS             8066..8479
                     /gene="rplP"
                     /locus_tag="TVB59_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEL1010254.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVSFGEYGLQATTSSWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEVAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            8489..8695
                     /locus_tag="TVB59_001367"
     CDS             8489..8695
                     /locus_tag="TVB59_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEL1010255.1"
                     /translation="MKLEEIKKFVAELRGLSQEELAKKENELKKELFDLRFQAAAGQL
                     DQTARLNEVKKQIARVKTVQSEMK"
     gene            8720..8983
                     /gene="rpsQ"
                     /locus_tag="TVB59_001368"
     CDS             8720..8983
                     /gene="rpsQ"
                     /locus_tag="TVB59_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011983253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEL1010256.1"
                     /translation="MMERNQRKTLVGRVVSDKMDKTITVIVETKRNHPVYGKRINYSK
                     KYKAHDEKNLAKEGDIVRIMETRPLSATKRFRLVEIVEEAVII"
     gene            9008..9376
                     /gene="rplN"
                     /locus_tag="TVB59_001369"
     CDS             9008..9376
                     /gene="rplN"
                     /locus_tag="TVB59_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEL1010257.1"
                     /translation="MIQQETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRPDGSYIKFDDNAAVIIRDDKTPRGTRIFGPV
                     ARELREGGYMKIVSLAPEVL"
     gene            9460..9765
                     /gene="rplX"
                     /locus_tag="TVB59_001370"
     CDS             9460..9765
                     /gene="rplX"
                     /locus_tag="TVB59_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEL1010258.1"
                     /translation="MFVKKGDKVRVIAGKDKGVEAVVLKALPKVNKVIVEGVAIIKKH
                     QKPNSENPQGAIVEKEAPIHASNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            9789..10331
                     /gene="rplE"
                     /locus_tag="TVB59_001371"
     CDS             9789..10331
                     /gene="rplE"
                     /locus_tag="TVB59_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEL1010259.1"
                     /translation="MANRLKEKYTNEVIPALTEKFNYTSVMAVPKVEKIVLNMGVGDA
                     VSNAKNLEKAAAELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKVRGLDIVIVTT
                     ANTDEESRELLKGLGMPFAK"
     gene            10347..10532
                     /locus_tag="TVB59_001372"
     CDS             10347..10532
                     /locus_tag="TVB59_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HEL1010260.1"
                     /translation="MAKKSMIAKNKRPAKYSTQAYTRCEKCGRPHSVYRKFKLCRVCF
                     RELAYKGQIPGVVKASW"
     gene            10865..11263
                     /gene="rpsH"
                     /locus_tag="TVB59_001373"
     CDS             10865..11263
                     /gene="rpsH"
                     /locus_tag="TVB59_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEL1010261.1"
                     /translation="MVMTDPIADFLTRIRNANQVKHEVLEVPASNIKKGIAEILKREG
                     FIKNVEVIEDGKQGIIRVFLKYGQNGERVITNLKRVSKPGLRIYSKREDVPKVLNGLG
                     IAIISTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            11585..12121
                     /gene="rplF"
                     /locus_tag="TVB59_001374"
     CDS             11585..12121
                     /gene="rplF"
                     /locus_tag="TVB59_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEL1010262.1"
                     /translation="MSRIGNKVIIIPAGVEIINNDNVVTVKGPKGELTREFNKNIEIK
                     VEGNEMTLVRPDDSKEMKTIHGTTRANLNNMVVGVSEGFKKELEMKGVGYRAQLQGSK
                     LVLSVGKSHQDEVEAPEGITFTVANPTSISVEGINKEVVGQTAAYIRSLRSPEPYKGK
                     GIRYVGEYVRLKEGKTGK"
     gene            12224..12580
                     /gene="rplR"
                     /locus_tag="TVB59_001375"
     CDS             12224..12580
                     /gene="rplR"
                     /locus_tag="TVB59_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEL1010263.1"
                     /translation="MISKPDKNKIRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVVVGKLVAERAVAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            12599..13093
                     /gene="rpsE"
                     /locus_tag="TVB59_001376"
     CDS             12599..13093
                     /gene="rpsE"
                     /locus_tag="TVB59_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEL1010264.1"
                     /translation="MAFKDNAVELEERVVAINRVTKVVKGGRRLRFAALVVVGDGNGH
                     VGFGTGKAQEVPEAIRKAVEAAKKSMIEVPMVGTTIPHEVYTNFGGAKVLLKPAVEGS
                     GVAAGGAVRAVIELAGIADITSKSLGSNTPINIVRATVEGLKQLKRAEEVAALRGISV
                     SDLA"
     gene            13108..13290
                     /gene="rpmD"
                     /locus_tag="TVB59_001377"
     CDS             13108..13290
                     /gene="rpmD"
                     /locus_tag="TVB59_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002959367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEL1010265.1"
                     /translation="MAQIKITLTKSPIGRKPEQRKTVVALGLGKLNSSVIKEDNAAIR
                     GMVTAISHLVTVEDVK"
     gene            13492..13932
                     /gene="rplO"
                     /locus_tag="TVB59_001378"
     CDS             13492..13932
                     /gene="rplO"
                     /locus_tag="TVB59_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEL1010266.1"
                     /translation="MKLHELKPAKGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRIPKRGFTNINTKEYALVNLDQLNAFEDGTEVTPVVLKEAGIV
                     RAEKSGVKILGNGELTKKLTVKAAKFSKSAEAAITAKGGSIEVI"
     gene            13949..15253
                     /gene="secY"
                     /locus_tag="TVB59_001379"
     CDS             13949..15253
                     /gene="secY"
                     /locus_tag="TVB59_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEL1010267.1"
                     /translation="MFLKILKDALKIKNVRNKIFFTIFIILIFRIGTHITVPGVNAKS
                     LEQLSELPFLNMLNLVSGNAMRNFSVFSMGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYISLVLAFAQSIGITAGFNTLSSVALVKTPDVRTYLLIGALLTTG
                     SVIVTWLGEQITDKGFGNGVSMIIFAGIISSIPNAIATIREDYFVNVKSGDLQSSYIV
                     VGILILAVLAIVFFTTYVQQAEYKIPIQYTKLVQGAPTSSYLPLKVNPAGVIPVIFAS
                     SITTIPSTIIPFFQNGRDIPWLTTLQGIFNYQSPTGMIVYALLIILFSFFYTFVQVNP
                     EKTAENLQKNSSYIPSVRPGRETEEFMSSLLKKLATVGAIFLAFISLVPIAAQQALNL
                     SSSIALGGTSLLILISTGIEGMKQLEGYLLKRKYVGFMNITE"
     gene            15405..16046
                     /locus_tag="TVB59_001380"
     CDS             15405..16046
                     /locus_tag="TVB59_001380"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEL1010268.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVETFELIHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGDLVPDEVTNGIVKERLAQADIKEKGFLLDGYPRTIEQAHALDETLK
                     ALGLTLDGVINIEVDPASLIDRLSGRIINKKTGETFHKIFNPPVGDYKEEDFYQREDD
                     KPETVKRRLDVNIAQGEPIIKHYRQAGIVRDIDGNKDISEVFADIKKVIENLK"
     gene            16164..16382
                     /gene="infA"
                     /locus_tag="TVB59_001381"
     CDS             16164..16382
                     /gene="infA"
                     /locus_tag="TVB59_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEL1010269.1"
                     /translation="MAKEDVIEIEGKVVETMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILVGDRVTVEMSPYDLTRGRITYRFK"
     gene            16408..16524
                     /gene="rpmJ"
                     /locus_tag="TVB59_001382"
     CDS             16408..16524
                     /gene="rpmJ"
                     /locus_tag="TVB59_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEL1010270.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPTNPKHKQRQG"
     gene            16542..16907
                     /gene="rpsM"
                     /locus_tag="TVB59_001383"
     CDS             16542..16907
                     /gene="rpsM"
                     /locus_tag="TVB59_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEL1010271.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGVSEDIR
                     VKDLTSDQEDAIRREVDTIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            16925..17308
                     /gene="rpsK"
                     /locus_tag="TVB59_001384"
     CDS             16925..17308
                     /gene="rpsK"
                     /locus_tag="TVB59_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEL1010272.1"
                     /translation="MAKPTRKRRVKKNIESGVAHIHATFNNTIVMITDVHGNALAWSS
                     AGALGFKGSRKSTPFAAQMAAEAAAKSAQEHGLKTVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            17355..18293
                     /locus_tag="TVB59_001385"
     CDS             17355..18293
                     /locus_tag="TVB59_001385"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEL1010273.1"
                     /translation="MIEFEKPIITKIDENKDYGRFVIEPLERGYGTTLGNSLRRVLLS
                     SLPGAAVTSIRIDGVLHEFDTIPGVREDVMQIILNVKGLAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIELVNPDHYLFTIADGYTLKASMTVAKKRGYVPAEGNKKDDAPVG
                     TLAVDSIYTPVKKVNYQVEPARVGSNDGFDKLTIEIMTNGTIIPEDALGLSARVLIEH
                     LNLFTDLTDVAKATEVMKEAEKVNDEKVLDRTIEELDLSVRSYNCLKRAGINTVFDLT
                     EKSEPEMMKVRNLGRKSLEEVKVKLADLGLGLKNDK"
     gene            18308..18694
                     /gene="rplQ"
                     /locus_tag="TVB59_001386"
     CDS             18308..18694
                     /gene="rplQ"
                     /locus_tag="TVB59_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEL1010274.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAYVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            complement(18912..19143)
                     /locus_tag="TVB59_001387"
                     /pseudo
     CDS             complement(18912..19143)
                     /locus_tag="TVB59_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195628.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            19999..21249
                     /locus_tag="TVB59_001388"
     CDS             19999..21249
                     /locus_tag="TVB59_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010275.1"
                     /translation="MSIDMYLSLSEEQAQSVEAVLARRQTAYQSLQETLIQLISNSPD
                     LSGRTYDSAKAYSSQVLIPLLKGCMLLDEAIITACKRLPSEYRSQVDQIDLKESDLVE
                     RIAQFDHVIGRYMDLISIEYSREEPSYSYISHLRSAEQLHRAVKRRLEEILRRLRHFD
                     TNSVHLFSTIQTLAAAVQIGMRQARTSWHAGSQVFVISEDMAWADTINSKWSKSKGLS
                     YLSDYVYDPDVLSKRAAINHSWIKTGYTMSKNFGKAVSKDYTKASFLSYGKAAKATGW
                     TSMAVDTGITSVREYNKKNSRAYGSEGKALIHASVAQIKSMGPIEGAIIGSKAGPWGA
                     LMGFVTGGINVTWGVVHPESKDNMFLWIQDKMDDVYDSIVQTDLGKGTHHAKESVKGH
                     IGRAIVRTWDFVSQSFGKGVGYDI"
     gene            21239..22114
                     /locus_tag="TVB59_001389"
                     /pseudo
     CDS             21239..22114
                     /locus_tag="TVB59_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677217.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            22135..22428
                     /locus_tag="TVB59_001390"
     CDS             22135..22428
                     /locus_tag="TVB59_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
                     /protein_id="HEL1010276.1"
                     /translation="MQKELLPLGSVVYLEGATSKLMIVGRGPIFESNGQNVYSDYVGV
                     MYPEGINPEDAIFFNHEDIAKTVFEGFKDEEEQRFLEVYSDWESTLEISKIKL"
BASE COUNT         6959 a         4062 c         5025 g         6561 t
ORIGIN      
        1 acttgattat tgcttagttt tttctaatgg aggattttta gtttagaagc tttgagttta
       61 gacctcaaaa cttagatatg gaattcgaaa ggcagtcact gctgtcaaca ttactttggg
      121 aaagttccta taagagactt ttcattagac tgaagtagct tcaatagctc taaaactacc
      181 tagactcaag taacaacaag tccttagaat tgattttcta agggcttttt tgctgcctca
      241 aggtaaagac atgttcagca acaaattgac tggctagacc agtcctttat ttatgctgat
      301 ggcttgagac tgctgggtta ttagcacaga aaatggctgt ctccaaatcc tagaaggctt
      361 atgattggaa tatgatataa tagtcaaaag aaatgatgag gtgatgtgaa gcaatgccaa
      421 tgatgtacca atcaacaaga aatgcagcta ataaggtaac agctagtcaa gcgattttaa
      481 gtggcctagc agatgatggt ggcttgttta ctcctacaag catgccagtg ctggatctag
      541 attttgagga gctaaagacc aagtcctatc aagaggttgc caagcttatt ttatcagcct
      601 tttttgatga ctatactgaa gcagaattag atgcttgtat ctcttctgcc tatgatgata
      661 agtttgatac agcagtgata gcacctctag ctacgttaaa ggattatcat aatttggagc
      721 tatttcatgg ctcaaccatc gcatttaagg acatggctct atctattttg ccttatctct
      781 tgacaactgc tgctaaaaag caaggtgtgg agcgaaaaat tgcgatttta accgctacct
      841 caggtgatac tggtaaggca gcaatggcag gctttgttga tgttccggga acggatatta
      901 ttgtctttta tcctaagtca ggcgttagca ggattcagga gctgcagatg atcacacagg
      961 ccggtcacaa tacccatgtt gtggcgattg aaggcaattt tgatgatgct caaacagagg
     1021 tcaagcgcct gtttaatgac cctgatttgc gtgagcggct agcagctcaa cagatacagc
     1081 tgtcttcggc caattcgatg aatattggtc gtttgattcc tcaggttgtc tattatattt
     1141 atgcttatgc ccagttggta aggcatcagc gacttgaagc tggagagacg attaacatag
     1201 tagtgccgac aggaaatttt ggcaatctac tggttgccta ctacgccaaa gaaattggac
     1261 ttcctgttgc caaattcatc tgtgcttcca atgaaaacaa tgtcttgaca gatttctttg
     1321 ctagtggtag gtatgataaa aagcgtccct tcaaggtgac tactagtcca tcaatggata
     1381 ttttggtgtc ttcaaattta gagcgcttgg ttttttattt actaggcaat gatgcccaaa
     1441 agacagcagt attaatgaag agcttggcag aaacaggtca gtatcagcta gctgatgcag
     1501 atcagtctat ccttgattta tttgcggcag gctttgcaac agagcaagag actgctaaag
     1561 agatcaaaac gatatttgag tctgatcatt atgtgcttga cccacataca gctgtagctt
     1621 cagctgttta tcgtgcttat cgggagcaat caggtgactc tagaccgact attgttgcgt
     1681 caactgctag tccttataag tttccgcggg tagttgtgga agctattagt ggtcagcagg
     1741 ttgccagtga ttttgaggcg cttgagcagt tggctgatat atcaggtgta gtcgtgccac
     1801 aagcggtcaa tggcttacag gaggcgccca ttcgtcatag ccttttagtg acagtagcag
     1861 atatgcagca ggcagtagag gcttatcttg gagtatagga ggcataaagg agctcccttt
     1921 caattgatat gaatataatg actcacaata gaaaaaagat actgtccttg gcccttccat
     1981 caatggcaga aaatatattg caaatgctga tgggaatgat agacaattat ttggctgctc
     2041 aaattggact tacggctgtt tcaggcattg cgattgctaa taatattctg acgatttatc
     2101 aggccctttt tatcgcatta ggtgctgcag tctccagtct cattgctaga agcgtaggag
     2161 agcaaaacca ttctaaagaa atcgactaca tggcaaatgc tatcttagta acgggggctc
     2221 tatcagttct tctaggcttg atgtccgtag tgggacataa aagcatatta gcctttctgg
     2281 gagcagctag tctggtagct agacttggtg ggcagtattt agccattgtc ggtggaatga
     2341 ttcttagtct tggtcttttc acgagcttag gtgcgattat tcgtgctaag ggccagccta
     2401 gcattcccat gaaggtcagc cttttaacta atttgctaaa cgctgtattt tcagcccttt
     2461 ctctttacat atggggattt ggagtgatag ggattgcttg gtcaactgtt gcatcacgtc
     2521 tcattggagt tgttattcta tgtcactttc ttcctattaa agaaattatt aaacgttttg
     2581 ctaatccctt agataaagag atctttagcc tctctcttcc agcggctggt gagcggctca
     2641 tgatgcgagc tggtgatgtg ctgattgtta ctattattgt tagatttgga acagaggcct
     2701 tggcaggcaa tgcgattgga gaaaccttaa ctcaatttaa ttatatgccg ggacttgcta
     2761 tgtcaactgc gacagtcatt ttagttgcca atcagttggg cagtggcaaa ggggctacaa
     2821 tagcgaaaac tgtaaaagaa acctttttgt tagccaccct gatgatgctt gttatgggct
     2881 tgatcactta tttgctaggc cctaatctac tgcccttatt tacagcagat gccaaggctc
     2941 agcaggctgg tatggttgtc ttagtctttt ctcttttggg ggtaccagca acagccggga
     3001 ccttggttta tacagcagcc tggcagggta tcggacaagc taagcttccc ttttatgcaa
     3061 caacgattgg tatgtggctg gttcggattt ctttgggcta ctttattgga gtaaccttaa
     3121 attatggagt aataggtgtt tggcttgcga ctattttgga caatgctacc agatggctca
     3181 ttcttgcagt ggcttttaag aagcagcaaa ggcagctttt ttcggactgt catagctaaa
     3241 ctttgtattt aggtctcaag acttctgagt ggtgactttc cttttgggag tcagccactg
     3301 tcatcagaat gtaaagtacg cctgaggctc tgtttgctaa tagcttctct tatctgcgga
     3361 agatcaaaga ggattgctgg aacagctgag gtttgtcttc aatctggctt gccctttctt
     3421 agggcaagtt tttttgaaaa aatcccctga aaggcttgca atgccttatt aattctgcta
     3481 ttatattatg gtgctgtaaa aatacagctt tagctgtgat acgagaggtt gcgacacgct
     3541 cggttgcatt gccacgtgac aggtgtcggt tttctcgagg agctagccta ttatcgtaaa
     3601 tagacgagag gagaaaagat ggcaaacaaa aaaatccgta tccgcttgaa agcgtacgaa
     3661 caccgtacac ttgatacagc ggcagaaaaa atcgttgaaa ctgcaactcg tacaggtgca
     3721 acagtagctg gaccagttcc acttccaact gaacgtagtc tttacaccat tattcgtgcg
     3781 actcacaatt ataaagattc tcgcgaacaa tttgaaatgc gtacacacaa acgtcttatt
     3841 gatattgtga acccaacgca aaagactgtt gatgcactta tgaaattgga ccttccaagt
     3901 ggtgtcaacg tagaaatcaa gctttaattg tttgaaacat gagtgaggaa cgagttcata
     3961 tctaattgaa cacaggctaa actctgtgtg aaaaagagac acagccgttc taattttaat
     4021 tagattacgg atgtggctac ctgtaggtgt aaatcttcct agaaacagaa gtttcttcgt
     4081 cagatttcct attttcactg tgagtttgac gccttaagta tcttgctttg agcataaaaa
     4141 acgctcgtaa aaaacttttt tgagcataaa aaacgctcac taaaaacttt ttgaaatatt
     4201 attaagaaaa ggaattattt tctcatgaca aaaggaatct taggggaaaa agtgggaatg
     4261 actcaaatct tcactgaatc cggtgaattt atccctgtta ctgtcatcga agcaactcca
     4321 aacgttgtgc ttcaagttaa gactgttgaa acagacggtt acgaagcaat tcaagttggt
     4381 tttgatgata aacgtgaagt attgagcaac aaacctgcca aaggccatgt agcaaaagct
     4441 aacacagctc ctaagcgctt cattcgtgaa ttcaaaaaca ttgaaggctt agaagtaggt
     4501 gcagaaatca ctgtggatat cttcgcagct ggggatgttg ttgatgtaac tggtacttca
     4561 aaaggtaaag gcttccaagg tgttatcaaa cgccatggtc aatcacgtgg tccgatggcc
     4621 catggttctc gttaccatcg tcgtccaggt tctatgggac ctgtttcacc aaaccgcgtt
     4681 ttcaaaaaca aacatttggc aggacgcatg ggtggcaatc gtgtaactat tcaaaatctt
     4741 gaaattgtac aagttatccc agaaaagaac gttattctta ttaaaggtaa cgtaccaggt
     4801 gctaagaaat ctcttatcac catcaaatca gcagttaaag ctgctaaata ataagaaagg
     4861 agaaaacagt taaaaatggc aaacgtaaaa ctatttgacc aaactggtaa agaagttagc
     4921 acagttgaat taaatgatga tatctttggt atcgaaccaa acgaatcagt tgtttttgat
     4981 gttgtaatca gccaacgtgc tagccttcgc caaggtactc atgcggttaa aaaccgttca
     5041 gcagtatcag gtggtggacg taaaccttgg cgtcaaaaag gaactggacg tgctcgtcaa
     5101 ggttctatcc gctcaccaca atggcgtggt ggtggtgttg tctttggacc aactccacgt
     5161 tcatatggat acaaacttcc acaaaaagtt cgtcgccttg ctttgaaatc agtttactca
     5221 gcaaaagttg ctgaagataa atttgtagct gtagaaagcc tttcatttgc agcaccaaaa
     5281 acagctgaat ttgcaaaggt gctttcagct cttagcattg atacaaaagt acttgttctt
     5341 gttgaagaag gaaatgaatt tgcagcactt tctgcacgta accttccaaa cgtagctgtg
     5401 gcaacagcag cgactgcaag tgttcttgat atcgtaaacg cagacaaact tcttgtaacg
     5461 aaagaagcaa tctctacaat tgaggaggtt cttgcataat gaatttgtac gacgtaatca
     5521 aaaaaccagt tattactgaa aaatcaatgt atgcccttga agaaggtaaa tacacatttg
     5581 aagttgacac acgtgcgcac aaactgttaa tcaagcaagc tgttgaagct gcatttgacg
     5641 gagttaaggt tgcaagcgtc aatactgtta acgttaaacc aaaggctaag cgtgttggtc
     5701 gttacacagg ttttacttca aaaactaaaa aggctatcat cactcttaca gctgattcta
     5761 aagcaatcga gttgttcgca gttgaagctg aataatctaa ggaggaaata acgtgggtat
     5821 taaagtttat aaaccaacga caaatggccg tcgtaacatg acttctttgg atttcgctga
     5881 aatcacaaca agcacacctg agaaatcatt gcttgtttct cttaaaaaca aagctggtcg
     5941 taacaacaat ggtcgcatta cagttcgtca ccaaggtggt ggacacaaac gccattaccg
     6001 tttgattgac ttcaagcgta acaaagatgg tgttgaagca gttgttaaaa caatcgaata
     6061 cgatccaaac cgtactgcaa acattgcact tgtacattac actgacggag ttaaggctta
     6121 catcatcgct cctaagggtc ttgaagtagg tcaacgtatt gtttctggac cagatgcaga
     6181 tattaaggtt ggtaatgcac ttccattagt aaacattcct gttggtacag ttgttcacaa
     6241 cattgagctt aagcctggta agggtggaga gcttgtacgt gctgctggag cttctgctca
     6301 agtacttggt caagaaggca aatacgttct tgttcgtctt caatcaggtg aagttcgtat
     6361 gattcttgga acatgtcgtg caactgttgg tacagttggt aacgagcaac aatcacttgt
     6421 taacattggt aaagcaggac gtagccgttg gaaaggtatc cgcccaacag ttcgtggttc
     6481 tgtaatgaac cctaacgatc acccacatgg tggtggtgaa ggtaaagcac cagttggacg
     6541 taaagcgcca tctactcctt ggggtaaacc agcgcttggt cttaaaacac gtaacaaaaa
     6601 agctaaatct aacaagcttc ttgttcgtcg tcgtaacgaa aaataagcgg caaatctagc
     6661 ataagcttat tcaatcattc cgccagctcg gtagagtttg agcttgctct catgctcaag
     6721 ccgctgtggt acattattta aaggagaaaa ctacaaaatg ggacgtagtc ttaaaaaagg
     6781 acctttcgtc gatgagcatt tgatgaaaaa agttgaagct caagctaatg acgaaaagaa
     6841 aaaagtaatc aaaacttggt cacgtcgttc aacgattttc ccaagtttca tcggatatac
     6901 aatcgcagtt tatgatggcc gcaagcatgt acctgtgtac attcaagaag acatggtagg
     6961 tcacaagctt ggtgaatttg caccaactcg tacctacaag ggtcacgcag ctgacgacaa
     7021 gaaaacacgt cgttaatagg aggaggacac aatggcagaa attacttcag ctaaagcaat
     7081 ggctcgtaca gtgcgtgttt cacctcgtaa aacacgttta gtacttgatc ttatccgcgg
     7141 taagaaagtt gctgatgcaa tcgcaatctt aaaattcact ccaaacaaag cagctcgtgt
     7201 tattgagaaa actcttaact cagcaattgc taacgcagaa aataactttg gtttggaaaa
     7261 agctaacttg gtagtatctg aaacatttgc aaacgaagga ccaacaatga aacgtttccg
     7321 tccacgtgca aagggctcag cgtcaccaat caacaagcga acaactcacg ttacagtagt
     7381 tgtatcagaa aaataaggag gtaaaatcgt gggtcaaaaa gtacatccaa ttggtatgcg
     7441 tgtcggaatc attcgtgact gggatgcaaa atggtatgct gaaaaagaat acgcggatta
     7501 ccttcatgaa gatcttgcaa tccgtaaatt cattaacaaa gaattggcag aggcttcagt
     7561 ttcaacaatt gaaattgagc gtgctgtaaa taaagttatt gtttcacttc acactgcaaa
     7621 gcctggtatg gttatcggta aaggtggagc aaatgttgac gctcttcgcg ctcagcttaa
     7681 caaattaact ggaaaacaag tacacatcaa catcatcgaa atcaaacagc ctgatcttga
     7741 tgcccacctt gttggtgaaa acattgctcg tcagcttgag caacgtgttg ctttccgtcg
     7801 tgctcaaaaa caagctattc aacgtacaat gcgtgctgga gctaagggaa tcaaaactca
     7861 agtttcaggt cgcttgaacg gtgcagatat cgcgcgtagc gaaggctact cagaaggaac
     7921 tgttcctctt cacacacttc gtgcagatat tgactatgct tgggaagaag cagatactac
     7981 atacggtaaa cttggtgtta aagtttggat ttatcgtggt gaagttcttc cagctcgcaa
     8041 aaacactaaa ggaggcaaat aacagatgtt agtacctaaa cgtgttaaac accgtcgtga
     8101 gtttcgtgga aaaatgcgcg gtgaagcaaa aggtggaaaa gaagtatcat tcggtgaata
     8161 tggtcttcaa gctactacta gctcatggat cactaaccgc caaatcgaag ctgctcgtat
     8221 cgctatgact cgttacatga agcgtggtgg taaagtttgg attaaaatct tccctcacaa
     8281 atcttataca gctaaagcta tcggggttcg tatgggttct ggtaagggtg cacctgaagg
     8341 ttgggtagca ccagttaagc gtggcaaggt tatgtttgag gttgctggtg tttctgaaga
     8401 aatcgctcgt gaagcacttc gtcttgctag ccacaagcta ccagttaaat gtaaattcgt
     8461 aaaacgtgaa gcagaataag gagaagacat gaaacttgaa gaaatcaaaa agtttgttgc
     8521 tgagcttcgt ggcttgtctc aagaagagct tgctaagaaa gaaaacgaac tcaaaaaaga
     8581 acttttcgac cttcgttttc aagctgcagc aggtcaacta gatcaaactg ctcgtttgaa
     8641 cgaagttaaa aaacaaattg cacgtgtaaa gactgtgcaa tctgaaatga aataatagat
     8701 tgggaaagga gtattctaaa taatggaacg taatcaacgt aaaacccttg ttggacgtgt
     8761 tgtatctgac aagatggaca aaacaatcac tgttatagtt gaaacaaagc gtaaccaccc
     8821 agtctatggt aaacgtatca actattctaa aaaatacaaa gcacatgacg aaaagaacct
     8881 tgctaaagaa ggcgatatcg ttcgtatcat ggaaactcgt ccactttcag ctacaaaacg
     8941 cttccgtctt gtagaaatcg tggaagaagc tgttattatc taatcaaact aaaaggagac
     9001 aattgaaatg attcaacaag aaactcgctt gaaagttgct gataatagcg gtgctcgtga
     9061 gatcttgact atcaaggttc ttggtggttc agggcgtaag tttgctaaca tcggtgacgt
     9121 catcgttgca tctgtaaaac aagctactcc tggtggagca gttaaaaagg gtgatgttgt
     9181 taaggctgtt attgttcgta caaagagtgg tgctcgtcgt ccagacggtt catacatcaa
     9241 atttgatgac aatgcggctg tcattattcg tgatgacaag actcctcgtg ggactcgtat
     9301 ctttgggcct gttgcacgtg aattgcgtga gggtggctac atgaagatcg tatcacttgc
     9361 accagaagta ctttaatttt aatcattaaa caaactaagt cccctaggct agcctagggt
     9421 gcccataggg gcgtaagaaa ataataggag aaacccataa tgtttgtaaa aaaaggcgac
     9481 aaggttcgcg ttattgctgg taaggacaaa ggtgttgaag ctgttgttct taaagcactt
     9541 ccaaaagtaa acaaagttat tgttgaaggc gtagccatca tcaaaaagca tcaaaaacca
     9601 aacagcgaaa atcctcaagg tgctatcgtt gaaaaagaag caccaatcca tgcatcaaac
     9661 gttcaagttc ttgataaaaa tggtgttgct ggacgcgttg gttacaagtt tgtagacggc
     9721 aaaaaagttc gttacaacaa aaaatcaggc gaagtgcttg attaatcacg aaggaaagga
     9781 gaagcataat ggcaaatcgt ttaaaagaaa aatatactaa cgaagtaatt cctgcgttga
     9841 cagagaagtt taattacaca tcagttatgg ctgtgccaaa ggttgagaaa atcgttctta
     9901 acatgggtgt gggtgacgct gtatcaaacg ctaaaaacct tgaaaaagct gctgcagaat
     9961 tggcgcttat ctcaggtcaa aaaccactta ttactaaagc taagaaatca atcgctggct
    10021 tccgtcttcg tgaaggtgtt gctatcggtg cgaaggtgac acttcgtggc gaacgcatgt
    10081 acgaattcct agacaagcta gttagcgttt cacttcctcg tgttcgtgac ttccatggtg
    10141 ttccaacaaa atcatttgat ggtcgtggta actacactct tggtgtgaaa gaacagctta
    10201 tcttcccaga aatcaacttt gatgatgttg ataaagtgcg tggtcttgat attgttatcg
    10261 taacaactgc taacactgac gaagaatcac gtgaattgct taaaggtctt ggaatgcctt
    10321 ttgcaaaata atagggggta actaaattgg ctaaaaaatc tatgattgct aaaaacaaac
    10381 gtcctgcgaa gtattctaca caagcttaca ctcgttgtga aaaatgtgga cgtccacatt
    10441 ctgtttaccg caagtttaag ctttgccgcg tttgcttccg cgagttggct tacaaaggcc
    10501 aaatcccagg tgttgttaaa gcgtcttggt aaaatgatga tgtgagagcg ttaagctacc
    10561 taagcaaaaa taggaaaatt gacgaagagt ctaaatactc taggaaattt tgcacctaaa
    10621 ggtagtagct tgaactcagt tcaaatgaac aaataatact atcagatatt atgtctgatt
    10681 cgatgcaaag gcaaagtgtc aatttgaaca cgggcgaaag ccggtgtcaa aaagataaac
    10741 attccttgga ggttttccct cctgcggaag tttcctattt tgactttggc ttttagcgcc
    10801 ctttgtatca tcgattaact agcaagtgca gcttgcaaac tactagtaag aggagaataa
    10861 taaaatggtt atgactgacc caattgcaga ctttttgaca cgtattcgta atgctaatca
    10921 agtaaagcat gaagtgttag aagtacctgc atcaaatatt aaaaaaggga ttgcagaaat
    10981 ccttaagcgt gaaggcttta tcaaaaacgt tgaagttatt gaagatggca aacaaggaat
    11041 tattcgcgta tttcttaagt acggtcaaaa tggtgaacgt gtcatcacta acttaaaacg
    11101 tgtttcaaaa ccaggtcttc gtatttattc taagcgtgag gatgttccaa aggttcttaa
    11161 tggactagga attgcaatta tttcaacttc agaaggtctt ttgactgata aagaagctcg
    11221 tcaaaagaac gttggtggag aagttatcgc atacgtttgg taatttaaga gacaaaagcc
    11281 gtaacgaaca atctaaaatt agaaaattat tgtggcttgc ttgcaaacaa aatagtttgt
    11341 ctattttaga tggcagttcg tcggctgtgc tcaaatgatg aacactatca acatagcaaa
    11401 cgtaaaagaa ctaattgaac atgggctaaa gtctgtgtga aaaagataaa tttttctaga
    11461 aaccttggtt tcatagtaat gtttcctatt ttcactttgc cttttacgcc ctaagtatct
    11521 tagttcaccc cgtgaaaact cgtcgcgtaa gcggcctgat aatttaacag gagaaaaaat
    11581 taatatgtca cgtattggta ataaggttat tattatccct gcaggcgttg aaatcattaa
    11641 caacgacaat gttgttactg taaaggggcc taaaggagag ctcactcgtg agtttaacaa
    11701 aaatattgaa atcaaagtcg aaggaaacga aatgactctt gtacgtcctg acgactcaaa
    11761 agaaatgaaa acaattcatg gtacaactcg tgcaaacttg aataacatgg ttgttggagt
    11821 ttcagaaggt ttcaaaaaag agcttgaaat gaagggtgtc ggatatcgtg cacagcttca
    11881 aggctctaag cttgttcttt cagtaggtaa atctcaccaa gatgaggtgg aagctccaga
    11941 agggattaca tttactgtag ctaatccaac atcaatttca gttgagggta tcaacaaaga
    12001 agttgttggt caaactgccg cttacattcg tagcctacgt tcaccagagc cttacaaagg
    12061 taaaggtatt cgttacgttg gtgagtatgt acgccttaaa gaaggtaaaa caggtaaata
    12121 atgttcttag tggaatatgg cataggcttg cttatgtcat gctctacaag ctcaattgat
    12181 aatttgtcgg aaagacaaac ttaaatatta agaggtgaaa attgtgattt cgaaaccaga
    12241 taaaaacaaa atccgccaaa aacgccatcg tcgcgttcgc ggtaaactct ctggaactgc
    12301 tgatcgccca cgtttgaacg tattccgttc taatacaggc atctacgctc aagttattga
    12361 tgacgtagcg ggtgtaacgc tcgcaagtgc atcaactctt gataaagaag tttctaaagg
    12421 aacaaaaact gaacaagctg ttgtagtcgg caaacttgtt gctgaacgtg cggtggctaa
    12481 aggtatttct gaagtggtgt ttgaccgcgg tggatatctc tatcatggac gtgttaaagc
    12541 tttggctgat gcagctcgtg aaaacggatt gaaattctaa tagggaggac acaaaataat
    12601 ggcatttaaa gataatgcag ttgaacttga agaacgcgtt gttgctatta accgcgttac
    12661 aaaagttgtt aaaggtggac gtcgtcttcg ttttgcagct cttgtagttg ttggtgatgg
    12721 aaacggacat gttggattcg gtactggtaa agctcaggaa gtaccagaag ctattcgcaa
    12781 ggcagttgaa gctgctaaaa agagcatgat tgaagtgcca atggttggca caacaattcc
    12841 tcacgaggtt tacactaact ttggtggagc taaagtattg ttgaagccag ctgtagaagg
    12901 ttctggagtt gctgctggtg gtgcggtacg tgccgtcatc gaattagcag gtattgctga
    12961 tattacttca aaatctcttg gttcaaacac tccaatcaac atcgttcgtg caactgttga
    13021 aggattaaaa cagcttaaac gtgcagaaga agttgccgca cttcgtggca tctcagtttc
    13081 tgacttagct taagaaaggg gatcatcatg gctcaaatta aaattacttt gactaagtct
    13141 ccaatcggac gtaagccaga acaacgtaaa acggttgttg cccttggact tggtaaatta
    13201 aactcttcag ttatcaagga agataatgct gctattcgtg gtatggtgac agcaatttct
    13261 cacttggtga cagttgaaga tgtcaaataa agagttagct agaaatctct gatttcttgc
    13321 attagcatgc agaaccggct tttgtgagtt attcctttga atgacaagca gtggtcggtt
    13381 ggtgcatata gcatcaggct atgacatagc ttgatcatgt ataggcgagt ttctatggag
    13441 agtcctttcc cttcatagag gcgctagcat tttacaaaaa aaggagaaaa aatgaaactt
    13501 catgaattga agcctgccaa aggctctcgt aaagtccgca atcgtgttgg acgcggtact
    13561 tcatcaggca atggtaaaac atctggacgc ggtcaaaaag gtcaaaaggc tcgtagtggt
    13621 ggtggcgtac gtctaggctt tgaaggtgga caaacaccct tgttccgtcg tattccaaag
    13681 cgtggattta caaatatcaa cactaaagag tatgctcttg ttaaccttga tcaattaaac
    13741 gcttttgaag atggcacaga agtaactcca gttgttctta aggaagctgg aatcgttcgt
    13801 gctgaaaagt caggcgttaa aattcttggt aacggcgaat tgactaaaaa attgactgtt
    13861 aaagcagcga aattttcaaa atctgctgaa gcagccatta ctgctaaggg tggttcaata
    13921 gaagtcatct aatgagggga tactcattat gttcttaaaa atactcaaag acgcattgaa
    13981 gataaagaat gttagaaata aaatattttt tacaatcttt attatcctta tattccgtat
    14041 tggaacacat atcactgttc ctggtgtaaa tgcaaaaagc ttagagcagc tgagtgagct
    14101 tcccttccta aatatgttga acttggtcag cggtaatgca atgagaaact tttcagtttt
    14161 ctcaatgggt gttagtccct atattacagc ctcaatcgtt gttcagctat tgcagatgga
    14221 tattttgccg aagtttgttg agtggggaaa acaaggtgag gttggccgtc gtaagctaaa
    14281 ccaagcgacg cgctatattt cccttgtctt agcctttgct caatctatcg gtattacagc
    14341 gggttttaac accttatcaa gtgtggccct agtcaaaaca ccagatgtaa gaacctattt
    14401 actgattgga gctttactga caacaggtag tgtgattgtg acctggcttg gtgaacagat
    14461 taccgataaa ggctttggta atggggtgtc tatgattatc tttgcaggta tcatttcctc
    14521 tattccaaat gctattgcaa ccattcgtga ggattatttt gtcaatgtga agtcaggtga
    14581 cctacagtca tcttatatcg ttgttggtat tctcattctt gcagtgcttg ctatcgtctt
    14641 tttcacaacg tatgttcagc aggcggaata taaaattcca atccaatata caaagcttgt
    14701 tcagggtgcg cctacaagct cataccttcc cttaaaagta aatccagctg gtgttattcc
    14761 cgttatcttt gccagctcga ttacaacaat tccaagtacg attatcccgt tctttcaaaa
    14821 tggcagagat attccatggt tgacaacttt gcaaggaatt tttaactatc aatctccaac
    14881 aggaatgatt gtttatgcct tgttaattat cctgttttca ttcttctata cctttgttca
    14941 agtaaatcct gagaaaacag ctgaaaatct acagaagaat tcgtcctata ttccaagtgt
    15001 tagacctgga cgagaaacag aagaatttat gtcatccttg ctaaagaaat tggcaactgt
    15061 gggtgctatc ttcctagcat ttatatctct tgttccaatt gcggcacaac aagctcttaa
    15121 cctatcttct agtattgcat taggtggaac tagcttgctg attttgattt cgacaggtat
    15181 cgaaggtatg aagcagcttg aaggttacct tctcaagaga aaatatgtcg gatttatgaa
    15241 tattacagaa tagaatatgg gttgacactg tcaaccttct attttgtttt taaatgacaa
    15301 taagatttac agagccttgg ttcctatctt cttattgcca tttgaaaaca aaaacaagga
    15361 aaactaaatt tcctattatc tttatgtcaa aagaggagaa aaagatgaat cttttaatca
    15421 tgggcttacc tggtgccggt aagggtacac aggctgcaaa gattgttgaa acctttgagc
    15481 ttattcatat ttcaacagga gatatgttcc gcgctgcaat ggctaatcag actgaaatgg
    15541 gagttcttgc gaaatcttat atcgataagg gtgatttggt gccagatgag gtaaccaatg
    15601 gtatcgttaa agaacgctta gcacaagctg atattaaaga aaagggattt cttttagatg
    15661 gctatcctcg taccattgag caggcacatg ccttagatga aaccttaaaa gcattgggac
    15721 ttacgttaga tggtgtgatc aacattgagg ttgaccctgc gtcactcatt gacaggctta
    15781 gcggtcgtat catcaacaaa aaaacagggg aaaccttcca taagatcttt aacccaccag
    15841 tgggagacta taaggaagag gacttttatc aacgtgaaga tgataagcct gaaacagtta
    15901 agcgtcgctt agatgttaat attgcacaag gtgagcctat tatcaagcat tatcgtcaag
    15961 caggcattgt tcgtgacatt gacggaaaca aggacatttc tgaggtcttt gctgacataa
    16021 aaaaggtcat cgaaaacctg aaataaattc cagaaaatcg cttgcgaaag tgattttatc
    16081 gtgatatact agactagtct gacttataat tgttacctct gtgctcagag gacatcaaat
    16141 cgaaatttag ggggtacttt tgcgtggcaa aagaagacgt gattgaaatt gaaggtaaag
    16201 ttgtcgaaac tatgccaaat gcaatgttta ctgttgaatt ggaaaatgga catcagattt
    16261 tagcaaccgt atcaggaaag atccgcaaaa attacattcg tattttagtg ggtgatcgtg
    16321 ttactgtaga gatgagtcct tacgacttga cacgtggacg tatcacatac cgctttaaat
    16381 agtcgaaata attggaggga ttaaaacatg aaggtaagac catcggttaa accaatttgc
    16441 gaatactgca aggttattcg tcgtaacggt cgtgttatgg taatttgtcc gacaaatcca
    16501 aaacacaagc aacgtcaagg ataagataga aaggagaaaa aatggctcgt attgctggag
    16561 ttgatattcc aaatgataag cgtgtagtaa tttcacttac ctatgtgtat ggaattggtc
    16621 ttgcaacatc taaaaaaatc ttagcagcag caggtgtctc tgaggacatt cgtgttaaag
    16681 atttgacatc agatcaagaa gacgctatcc gtcgcgaagt ggatacaatt aaagttgaag
    16741 gtgatcttcg tcgtgaagta aacctaaata tcaagcgttt gatggaaatc ggttcatatc
    16801 gtggaattcg tcaccgtcgt ggacttcctg tacgtggaca aaacacaaaa aacaatgctc
    16861 gtactcgtaa aggtaaagct gttgcgattg caggtaagaa aaaataaaat aggaggtaaa
    16921 aaaattggct aaaccaacac gtaagcgtcg tgtgaaaaag aacatcgaat ctggtgttgc
    16981 acatattcac gctacattta ataacactat tgttatgatt acagatgtgc acggtaatgc
    17041 tttagcatgg tcatcagccg gtgctcttgg ttttaagggt tctcgtaagt caactccttt
    17101 tgctgctcaa atggctgcag aggctgctgc gaaatctgca caagaacatg gtttaaaaac
    17161 tgttgaagtt actgtaaaag gtcctggttc aggtcgtgaa tcagctattc gtgccctagc
    17221 tgctgccggt cttgaagtaa ctgccattcg tgatgtgact cctgtaccgc ataatggtgc
    17281 tcgtcctcca aaacgtcgtc gtgtataatc acagtaacaa atagtacaca agtttcgttt
    17341 cgaggggtga aagaatgatt gagtttgaaa aaccaataat aacaaaaatt gatgaaaata
    17401 aagattacgg tagatttgta atcgaaccac ttgaacgtgg atatggtaca actctaggta
    17461 attcacttcg tcgtgtactc ttgtcttcac ttccaggtgc agctgttaca tcaatcagaa
    17521 ttgatggagt actacacgaa tttgatacaa tcccaggtgt acgtgaagat gtcatgcaaa
    17581 ttatccttaa tgttaaggga cttgctgtga aatcatacgt cgaagacgaa aagattatcg
    17641 agcttgatgt agaaggtcca gcagaggtaa cagctggaga tattctcaca gatagcgata
    17701 tcgaacttgt taaccctgat cattatcttt ttactattgc tgatggttat acattgaagg
    17761 cttcaatgac tgtcgctaaa aaacgcggct atgtaccagc agagggtaat aaaaaagatg
    17821 atgcacctgt ggggacgttg gcagtagatt caatctatac gccagtaaaa aaggttaatt
    17881 atcaagttga gcctgctcgt gtaggtagta atgacggctt tgataaattg actattgaaa
    17941 tcatgacaaa cggaacaatt attcccgaag atgccttagg tttatctgct cgagttttaa
    18001 tcgaacactt gaatttattt actgatttaa cagatgttgc aaaggcaact gaagtgatga
    18061 aggaagctga aaaagtgaac gatgaaaagg tacttgatcg cactattgag gaacttgatt
    18121 tgtccgtacg ctcatataac tgcttgaaac gtgccggtat taatactgtc ttcgatttaa
    18181 cagaaaaatc tgagcctgaa atgatgaagg tccgtaacct tggacgtaag agtcttgagg
    18241 aagtaaaggt caagcttgct gacttaggtt tgggactaaa aaacgataaa taacatagga
    18301 ggataaaatg gcttaccgta aactaggacg cactagctca caacgtaaag caatgcttcg
    18361 tgacttaacg acagatcttt tgattaacga atcaattgta acgacagaag cacgtgcaaa
    18421 ggaaatccgt aaaacagttg aaaaaatgat tactcttggt aaacgtggtg atcttcatgc
    18481 tcgtcgccaa gcagctgcat acgttcgtaa cgaaatcgca tcagaaaact atgatgaagc
    18541 tactgataaa tacacatcaa caacagctct tcaaaaactt ttctctgaaa ttgcgcctcg
    18601 ttatgcagaa cgcaacggtg gatacactcg tatccttaaa acagaaccac gccgcggaga
    18661 tgctgctcca atggcgatta ttgaattagt ttaattttta tcaattttgt tgagtgttat
    18721 gatgatggag cagttccttt aagctgttct tagtctagct ctggtctacc gctaggacct
    18781 ttcctagcgg taacactcac catgttgaga ataagtaacg cttgtttacg aaaggtctct
    18841 aagctgtagg tgcccttcgt aagcaggcgt tttgttgtga ctccatgtta actgtagtag
    18901 atgactaata tctaatatct agagaggatc agcttggtgc tctcttttct gatattaaaa
    18961 gcattgggaa tcttggtttt gaagttctta aagctcctaa agccaaagtc tttcgcttga
    19021 tgtctttggt catcttgtta gtggtctccg gcttagcatt ggaataaggt agttcaaagc
    19081 attggtgatg taagatctat acttcctgaa ggtcttgaaa accgttttga aggtgtgatt
    19141 gacctgtagc gggagtagat tagatcaatg gcgtttggct gctttgaaaa tttaggtgac
    19201 aattgttttt gtatctttgt ttaaaaatgg tataatatta aaacattaaa caaaatgtac
    19261 ataaaaaagc catataaaag aatgatatta agataatgtg atcaatagtt ttagaaaatg
    19321 aatgtgtaag gttaaggtat gcccccttga tataatgcta gttttacgaa gaggcattct
    19381 gtacagacat aatgcactct tacaaatgat acggtaattg ctcaacaagg cgcaacagcc
    19441 ttggcaaatg taatatttgc cttagctagc agcgaattag ttacgcttga tacatagaca
    19501 agggtttctg gcatacagca gcagatggtg tgcctgtctc agagagtggc tgcttggctt
    19561 atcctattca tgttttaaaa cttacaggag gtgttatgtg gcctttggtc gatggatatt
    19621 tagctaggtg aacagctatt agctgtaaat atgaggtagg agctttagtt tgcatgatgt
    19681 taaatgaatt gaaacagact taggaaagct tggcttagca actatcacgc aagttcttaa
    19741 caacgataaa gatcgtatgg gaaaatatga tcaagcatca acggacatga gatgtgtttt
    19801 atgaagaaac cattatactt ttataagact tatttagttg tttttctttg cggacttgtt
    19861 tgaggagtag tctacatagg caataggctc aggcttacag cacttaggag acattagagc
    19921 atgagaagca ctaactggct agtgatagaa aagtaatagc acagtgtttt tataactaac
    19981 aagaggagta gacattctat gagtattgac atgtatttga gcttatctga agagcaggca
    20041 cagagtgtag aggctgtctt agctaggcga caaacagcct atcaatcctt acaggagacc
    20101 ttgatccaat tgatttctaa cagtcctgat ttatcagggc ggacctatga ttctgctaag
    20161 gcttatagta gtcaagtgct aattcctttg ttaaaggggt gtatgctttt agatgaggcg
    20221 attataacag cctgtaagag gctacctagt gagtaccgta gtcaggtaga ccaaattgat
    20281 ttgaaggaga gtgatctggt tgagcgtatt gcccagttcg atcatgtgat tggtcggtac
    20341 atggatttga ttagtattga atacagtaga gaggagccta gctattctta tatctctcat
    20401 ttaagatcag ctgagcagct ccatcgggcc gttaagcggc gtcttgagga gatattgcga
    20461 aggctaaggc attttgatac caactcagtt cacctttttt cgactattca gactttggca
    20521 gcagcggtac aaataggcat gcgtcaagct aggacctcgt ggcatgcagg aagtcaggta
    20581 tttgtgattt cagaggatat ggcatgggcc gatacgatta attctaagtg gtcaaaaagt
    20641 aaagggttaa gctatcttag tgattatgtt tacgacccag atgtgctctc taagagagca
    20701 gctattaatc actcttggat taaaacaggc tatactatgt ctaaaaattt tggcaaagct
    20761 gtttcaaaag attatacaaa agcaagcttt ttgagctatg gtaaggcagc caaggcgact
    20821 ggctggactt ctatggcagt agatactgga ataactagtg taagggaata caataagaaa
    20881 aatagtagag cctatggcag tgagggcaag gcgcttattc atgctagtgt ggctcaaatc
    20941 aagagcatgg gacctataga aggggcgata attggcagta aagctggacc ttggggagca
    21001 ttaatggggt ttgttacagg aggcattaat gttacttggg gagtagtgca tccagagtct
    21061 aaggacaaca tgtttttatg gatacaagat aaaatggatg atgtttacga ttcgattgtt
    21121 cagacagatc ttggcaaagg gacgcaccat gctaaagaaa gtgtcaaagg tcatatcggt
    21181 cgagctattg taaggacatg ggactttgtc agtcaatcat ttggtaaagg agtgggctat
    21241 gacatttaaa gatcagcttt ttagtgggac gtttgagcaa tcaaaaaaga ttgtgtctaa
    21301 aagtatattg acagaagaag gtgcgcagat tggagtattc tcatctatga gtctatggaa
    21361 gagaataaca ggcttgatga tgttgccatt atttgctatt tcatatggag taggagttgt
    21421 gttacctgaa cactttcaac aatcaacaga aggagttcaa gctatttcat tggctgcaat
    21481 agagattatt gccagattag gacagttcag tcgatacttt atcatttgtt ttatttgtat
    21541 gtctgttgga ttaattatta gtaatatcct tccaaagcct aactaggctt atcaattatt
    21601 atatggcaat gctactctta ttatacttag tattacaact attatctcag ccttcccttt
    21661 aactgctggc cttacaattg cagcttttgg ctggatcggt tttttgcttc agctattgct
    21721 ttgcctttat ttgtggaagg tttgtgtcat agataagtgt caacagctac gcacagcaat
    21781 ttatcaagaa agcaccatag cacctgattg gggcagtaag ctagtaagct ttattaagtc
    21841 ttatggtggt atcttattag gcctctctgt tctcaaccgc tggactctca atctaggaga
    21901 gctagtcaag gaaagccctg gtttgttgag ttttctgtac ggctggattt ttctattgtt
    21961 catgtttttg atgctatttg cactgggtca agcgttaaaa aataccatca tagcctatta
    22021 tttttttaga tatcaaaaag aataccgcaa gcattttaat ataagcgatg agcagtggta
    22081 cggtaaatgg cgtttaaaaa tattattaaa ataaacgata taaggagtaa tcatatgcaa
    22141 aaagaattat taccgttagg aagtgttgtc tatctagagg gagcaacaag caagctaatg
    22201 attgtcggac gtggtcctat atttgaatct aatggccaaa atgtctacag tgattatgtt
    22261 ggagtaatgt atccagaagg gatcaatcca gaagacgcga tttttttcaa ccatgaagat
    22321 attgcaaaaa cagtctttga aggcttcaag gacgaagaag aacaacgctt tttagaagtg
    22381 tattctgatt gggagagtac tttagaaatt tccaaaataa agctatagat gaactgtagc
    22441 agatatattt gtcagtagat tgtcatgatt atattgaaag attatgactt tctctggctt
    22501 aaatacctct aaagttccaa agtttagaaa aggctttaaa atgagtgtta taatagcatt
    22561 tatgctcatt aaataaaggt agcatttcaa tagaatcggt aaaaaaa
//
LOCUS       DARYNN010000036        20897 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.036, whole genome shotgun sequence.
ACCESSION   DARYNN010000036 DARYNN010000000
VERSION     DARYNN010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20897)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20897)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20897
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.036"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            126..1541
                     /locus_tag="TVB59_001391"
     CDS             126..1541
                     /locus_tag="TVB59_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL1010277.1"
                     /translation="MRKNKLLRMIMLMTLLVPHLETARVLAEDTGAEASQVPATANEA
                     AIAQTGESTSTAAATSATDNSSSTTETTPNSGEPGATGSSSNTASSGSASGSTGQSTP
                     TSPAASPQPAPEVATQASQPALNIVPAAPTVDLSLTLALPSVNTYAAYVTHWSGQSAY
                     THNLLSRRYGIKAEQLDSFLKSTKIKYDEKRINGAALLQWEKKSGLDVRAIVAIAMTE
                     SELGTKGNATLLGSNMFGYALFDLDSKKPNQFNDELAIVKLTQETIIKNSNLNFEQQD
                     QKADKFAKKQLNFASDGGLYFTDTNGIGKRRAEIMEKLDAWIDQHGGTPEIPAELKIQ
                     SSSSFAVVPTGYKLSKSYDILSYQASSYAWGQCTWYVYNRAKELGYQFDSFMGNGGDW
                     RFKSGYSISKEPKVGYAVSFAPGQAGADGLYGHVSIVEDVRKDGSILISESNCLGLGQ
                     ISYRTFTAEQANQLTYVVGKS"
     gene            1743..5494
                     /locus_tag="TVB59_001392"
                     /pseudo
     CDS             1743..5494
                     /locus_tag="TVB59_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922617.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NEAT domain-containing protein"
     gene            5723..6628
                     /locus_tag="TVB59_001393"
     CDS             5723..6628
                     /locus_tag="TVB59_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme-binding protein"
                     /protein_id="HEL1010278.1"
                     /translation="MKIINEEHMIKRLFKKLMGGLVVLLVCLAAIGGKAYADKGELYS
                     CVIRRDYRHPVSGQIEDSGGEHAFEIGQGMVEGTVYSNGMLEVTSAGDLYLTFRMSLA
                     DFSGNYQFWVQPGGTGAFQAAAYSVTKVGTDTNGTTKDIAIALPDVNTVVRGSMYVEP
                     MGREVVFYLSPSELQEGYSGDMVASFAAGEAKTDHAVTAPAKADEKKAPSKPDSKDAK
                     SAPNPSARPVGQSSSPKKQSNPSKKGQAVGLSTSLDKSKQESSQKPVNNPLPVLVYYV
                     PTALLLSGALVLFIKKKRKNNEESH"
     gene            6612..7496
                     /gene="isdE"
                     /locus_tag="TVB59_001394"
     CDS             6612..7496
                     /gene="isdE"
                     /locus_tag="TVB59_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme ABC transporter substrate-binding protein
                     IsdE"
                     /protein_id="HEL1010279.1"
                     /translation="MKKVIKLIGLAVLSLVLSACVDQHPRAEKKADKERIVATSVAVV
                     DICDRLSLDLVGVCDSKLYQLPKRYDAVKRIGLPMNPDMEVIASLKPTWILSPNSLQN
                     DLEPKYQQLDTEYGFLNLTSLEGMYQSIDDLGDLFDRKKEAKRLRADYEEFYRAFKKK
                     HKGQKKPRVLILMGLPGSYLIATNKSYVGNLLELAGGENVYHSEDKEFLSANPEDMLQ
                     QQPELILRTAHAIPDKVKDMFDKEFAENDIWKHFEAVKSQQVYDLDNTLFGMSAKFNY
                     KEALNHLSQIFYGAKEVK"
     gene            7498..8520
                     /locus_tag="TVB59_001395"
     CDS             7498..8520
                     /locus_tag="TVB59_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEL1010280.1"
                     /translation="MQQGSQYSDQVTAARKRTTRLVYMVLLLMLLFGLMLYAVSVGGL
                     SVSYQRIFNGLFVAYDSEVALIYDLRFPRIVIALLAGAGIATSGVLFQAILKNPISDP
                     AIIGVCSGASFMVLLSSLLLPQLLFYGPLLSFVGGCVSFLMIYTLSWKKGLQPIRIIL
                     TGIAINALFLGLSRAITDFSKTSNPFVNALLSGNISQKTWADVGVLWPYTVLGLLLAI
                     GLARQCDLLLLNDGLIRNLGIDSNYLRLGISLVAVLLAAVSTSIVGVVSFLGLIVPHI
                     GRLLVGSKHSYLIPFSALLGAFVFLLADTLGRQLCYPLEISPAVIMSIVGGPYFIYLL
                     RRSDVI"
     gene            8517..9299
                     /locus_tag="TVB59_001396"
     CDS             8517..9299
                     /locus_tag="TVB59_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1010281.1"
                     /translation="MSHEQGLIRVEDLSFTYRDRPILDRLSFTIPKGKITTIMGANGC
                     GKSTLLGLLTKNIPVKSGQIFLEGQAISSISLKQFAQKVAVVHQDNQAVADLLVGDLV
                     AVASQAHRRFFKGSSQEDDDIVAWALEVTNLRELAFREMQELSGGEKQRVWIAMALAQ
                     KTGVLVLDEPTTYLDIKYQLDILALIKKINQELGMTIIMVLHDINQALAVSDCVLGLQ
                     KGAIYAQGSPQEVLDQAFVEAVFGVSLPFIEKQDRRFVLTTL"
     gene            9345..11108
                     /locus_tag="TVB59_001397"
     CDS             9345..11108
                     /locus_tag="TVB59_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HEL1010282.1"
                     /translation="MNDTTEKISRAKKKMLLRRLKERIAPKRFLLYVSAFLSWLQFLM
                     RLMSFYLIAKQFTAFLAGQALQLTRLLVILLILNAVGFGLAMIAKQLQGLASQFARDS
                     LKQSFFDAFIAMDGQFDQQSTEADVLTVASQGIDSLDTYYSYYLSLAMLTAFNCTTVL
                     LLVFLIYPIGGLVFILSLPLIPISIVAMQKRSKRIMNHYWSTYMDVGNLFMDDLKGLN
                     TLYSYQADERYEESFVNKAEAFRKATMQLLGFQLQAVGYMDAVMYLGIGLSGFLAVQA
                     LSAGGISFFDFLFFILIATEFFAPIREQGYGMHLVMMNTKMADQIFGFLDSVEAVDQD
                     KGVALPAFDRIDIQDLSFSHGEKALLRDITMTIKKGELTAVAGVSGQGKTSLAQLLLK
                     RYQADSGQIFLGDVTIDLASKQAINQEILYVSDQSTLLNMSIYENLAMAAQLTRKELL
                     SWIDEHGILSFIYWLPDGIDTIVGENGCHLSAGQRQQVICARALLSQRSCYIFDEATS
                     SLDAENEAAIHRLLQQLAKQAIVIVITHKMKYLKQADQVLFLSPEQSASLASPRELYR
                     HHLAYRQLVDTQVELEANLYG"
     gene            11101..12783
                     /locus_tag="TVB59_001398"
     CDS             11101..12783
                     /locus_tag="TVB59_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1010283.1"
                     /translation="MVKSDYSTYRLVLRLLAMMKHLLAWIALAVMFAVLGFVLTVGIP
                     TSLAYLGLEVMAGHAITFKWLYLFVAMALLRGLVRYGEHYFGHFVAFHSLAAFRRIVF
                     KKLRALSPARLDSQDSGHLLKMIGEDIEALEVFFAHTLAPICTAFISASLMAYYLWQV
                     SWKLALGAIVTYVLLAVIIPVYFSNVLQSLLKKQNEGRRAYVSSFLESLRSVKDLLQF
                     QSIEKRFKLLSNQSKHVNALDRQVAQAQFLQMAITFLALGLSILTFAYVTLFELSQQT
                     VTFAGGLLAFVAFTASFAPFLELGRLPLGFKRAMNAARNVFQLLDEEALVDKGDQRIS
                     SVTRIAVEDLTFAYPKHQETIYHHLSVAFEKKGIIGIQGESGSGKSTLMKIIMKWYNW
                     QAGHIFLSEVDSQTLNAASLQANFAYVPQNAQLFQQTLRDNITLGRKDISDDDIMELA
                     EACGMKERILACDEGLDTLVRGSADFSAGEAQRLELMRALLKRADCYIFDEPTSNLDS
                     LNEAIFIDLIKKHCRGMVFLISHRPSTLACADQLFCVRNGFLKEVNNERVNH"
     gene            12764..13357
                     /locus_tag="TVB59_001399"
     CDS             12764..13357
                     /locus_tag="TVB59_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEL1010284.1"
                     /translation="MKGLTIKDIMTTGAFAALYFVCVGLGAMLSILFDRSGNMLYAPA
                     FAALLGGPVYMLLIAKLQTFGPISLVGIIMGSFFFLTGHFFASMLPAILFGCLADGIA
                     LLGKYQSRLVNLLSYLVFAFVNSGPIILMWLLKDAYIQSLLARGKDMAYVNRIMYDFT
                     VANVSWFVGVVLLCALVGGLFGQYLLKKHFAKSGMLL"
     gene            13354..14034
                     /locus_tag="TVB59_001400"
     CDS             13354..14034
                     /locus_tag="TVB59_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEL1010285.1"
                     /translation="MRLDVRTKLLLLILANACFFFRIDGWLGTMIIGVLLGILFWLGQ
                     GRLAIGMTLLYALLLALSVLPLHVLPAYLFRLLSFAAVAGQLLYPSVLAALIFVKTTT
                     AYELVHGLRKWHVPEVCLLTLAVMLRFLPKIRQEGKIIRQSLKIRGIFLDSWAIVRQP
                     RRYMEYLLVPLLMSLLRSSQDLTIASLTKGLAIKKGASECFVSHLSWKDWGVQIWIFV
                     TIAYMVLQ"
     gene            13971..15425
                     /locus_tag="TVB59_001401"
     CDS             13971..15425
                     /locus_tag="TVB59_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1010286.1"
                     /translation="MEGLGGTDLDICDDSLHGSPVIKAKQLQFSYTNRRQTACELRDC
                     QIEAGQFIVLCGQSGSGKSTFLKLLNGLIPDYFSGQLQGSLKVLSHQAGQASVEVLSR
                     QVSSVFQNPASQFFYREVKHELVFPCENQGLEPALILERLDTLAADFDIKDLLEADML
                     KLSGGQKQRVAIAAAIMQGTAIMVFDEPTANLDHASVAAVKAYLKQLKAAGKTIIVAE
                     HRLHYLLDLADHFYYFSAGRLERVLSPKDLLALPDQEREELGLRRCELTAVTKALRAK
                     TVFEHYDPEHALQIKQLEVKAGSRVLYHLNQLSFGAGQITGITGANGLGKSQLALYLA
                     GIFEAKEAKISYLGVTLPAKDRLSITSLVLQDVGLQLFSETVEKELNLGHHRHQATDD
                     LVNRLGLSQLLDKHPASLSGGEQQRVMIAASLLSDKEIVILDEPSSGLDLLQMQALVS
                     LLKELKQQKKVVIVISHDEELLDQACDSIYQLSR"
     gene            15789..17804
                     /gene="recG"
                     /locus_tag="TVB59_001402"
     CDS             15789..17804
                     /gene="recG"
                     /locus_tag="TVB59_001402"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEL1010287.1"
                     /translation="MLLKSSIANLKGLGPKSAEKFQKLGIYQIKDLLLYYPFRYEDFK
                     SKSALELLDGEKAVLTGRVVTPPSVQYYGFKRNRLSFKLKQGELVISVSFFNQPYLLE
                     KIVLDQEVAIFGRWDQKKAALTGMKLLMTLEDDLQPVYHVAQGISQPTLIKAIRSAFD
                     SGALAQLEENLPEPLIQKYRLLPRQAAVYAMHFPKHMEDYKQALRRIKFEEFFYFQMN
                     LQVLKLANKAEGNGLAIPFHQQAVAKKIAALPFSLTRAQQRSLEEILADMTSGAHMNR
                     LLQGDVGSGKTVIASLAMYAAQTAGFQSALMVPTEILAEQHYDSLCQLFPDLSIALLT
                     SGMKAAEKRAALSAIADGSVDMIVGTHALIQDAVTYHKLGLVITDEQHRFGVNQRRLF
                     REKGNNPDVLMMTATPIPRTLAITAYGEMDVSIIDELPAGRKPIITRWVKHRQLDSVL
                     AWVKTELAKGTQAYVISPLIEESETLDLKNAVALEAELKDYFKASASVALMHGKMKAD
                     DKEMIMQRFKAKEIDVLVSTTVIEVGVNVPNATIMLIMNADRFGLSQLHQLRGRVGRG
                     SKQSYAILVADPKTDSGKERMTIMTTTNDGFVLAEADLKLRGSGEIFGTRQSGLPEFK
                     TADIVEDYHILEEARRVAAEIVAAKDWQLDPRWAPILANLRVADQFD"
     gene            complement(17924..18889)
                     /locus_tag="TVB59_001403"
     CDS             complement(17924..18889)
                     /locus_tag="TVB59_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEL1010288.1"
                     /translation="MKEILVLHTGGTISMQADEAGKVSPNQNNPMNQVGLSLEHIHLT
                     VVDFLNLPSPHITPHHMLKMYHYIQQRASQFDAVVITHGTDTLEETAYFLDTMVLPVE
                     LPIVITGAMRSANEIGSDGIYNYLTALRVASHEKAKGKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGVVMKDDLLFFKTAEPRVRFELRHISGTVPIIKAYAGMGDGSI
                     LSLLTPDRIQGLVIEALGAGNVPPLAVSELEKLIASGIPVVLVSRCFNGIAEPVYAYR
                     GGGASLKRAGVMFVKELNAPKARLKLLIALNAGLTGQELKDYIEG"
     gene            18961..20349
                     /locus_tag="TVB59_001404"
     CDS             18961..20349
                     /locus_tag="TVB59_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL1010289.1"
                     /translation="MTIKAVFFDIDGTLLNDRKNVQKTTQRAIQQLKKQGIMVGLATG
                     RGPAFVQPFLENFGLDFAVTYNGQYILTRDKVLYQNQLPKSTIYKIIRYASDKKREIS
                     LGTASGLAGSRIIDMGTSPFGQMVSSIVPRSLVKTVEGSFKNLIRRFKPQSFSNLVTI
                     MREPIYQIVLVASVDDTQKIKERFPHIKVTRSSPYSLDLISSGQSKIKGIERLGEMFG
                     FELSEVMAFGDSDNDLEMLSGVGVGVAMGNAEAVVKSGAHFTTASNNNDGISKALAHY
                     GLIHFDVEKSFKSRDDNFNKVKDFHRLMDGDTIETPRGYSLKEAGYRADFKVEELVEF
                     LYAASQGDKHRFSQALIDLHAALDKAAKKVQAKEHPESPLVGQVDALTDLLYFTYGSF
                     VLMGVDPQPIFETVHEANMGKIFPDGKAHFDPITHKIQKPDDWQERYAPESAIKKELD
                     KQLQKSLQRLEK"
     gene            complement(20635..>20897)
                     /locus_tag="TVB59_001405"
     CDS             complement(20635..>20897)
                     /locus_tag="TVB59_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEL1010290.1"
                     /translation="AKEVLGDFEKQAREAGLTEVKQVIEFGNPKTLLAHDIPDKEEVD
                     LIMVGATGLNTFERLLIGSSSEYILRHAKVDLLVVREHDKTL"
BASE COUNT         5598 a         4151 c         5093 g         6055 t
ORIGIN      
        1 aataagaaaa ggcccttacc tttatccgag tattaaggca ttaatacaaa aaatcttgca
       61 ttttattttg cttcaatgtt ataatgtagg ttagaataga gcagaaagaa gtgattgaat
      121 actaaatgag aaaaaataaa ttattaagaa tgataatgct gatgactctt ctggtacctc
      181 atttagagac cgcaagagta ttggcagagg atacaggagc tgaagccagc caggttccag
      241 ctactgctaa tgaggctgca atcgcccaga ctggtgagtc cacttcgaca gcagctgcta
      301 cctcagctac tgacaactcc tcatcaacca ctgagactac tcccaacagt ggagaacctg
      361 gagcaacggg gtcatcaagc aatacagcta gctctggatc agcttctggt tctactggac
      421 agtcgacacc tactagtcca gcagctagcc ctcagccagc ccctgaagtt gctacacagg
      481 catctcagcc ggcactgaat attgttcctg ctgctcctac agttgatttg tccttgactc
      541 tggccctgcc ttctgtaaat acctatgctg cttatgtgac gcattggagt ggtcagagtg
      601 cttataccca taacctcttg tctaggcgct atgggatcaa ggcagagcag cttgatagct
      661 ttttaaagtc taccaagatc aagtatgatg agaagcgaat taacggtgct gccttgctgc
      721 aatgggaaaa aaagagtggg ctagatgtgc gggcgattgt agccattgca atgacagaaa
      781 gtgagctagg aaccaaggga aatgcaacct tactaggctc taacatgttt ggctatgcgc
      841 tttttgacct tgattcgaaa aagccaaatc agtttaatga tgagcttgct attgttaagc
      901 tgacacagga gacgattatc aaaaatagca accttaattt tgagcagcag gatcaaaagg
      961 ctgataaatt tgccaaaaag cagttgaact ttgctagtga tggtggtctt tacttcacag
     1021 ataccaatgg cattggcaag cgtcgcgctg agatcatgga aaaattagat gcttggattg
     1081 atcagcatgg aggcacgcca gagattccgg ctgagctgaa aattcaatcc tcttcaagct
     1141 ttgctgttgt tcctacaggc tacaagctgt ctaagagcta tgatatttta agctatcagg
     1201 cgtcaagcta tgcttgggga caatgtacct ggtatgttta taatcgcgct aaggagctag
     1261 gctatcagtt tgattccttt atgggaaatg gtggtgactg gagatttaag tctggctaca
     1321 gtatttctaa ggagccaaag gtaggctatg cggtttcctt tgctccaggt caagcgggtg
     1381 ctgacggtct ttatgggcac gtctctattg ttgaggatgt cagaaaggac ggctccatcc
     1441 tgatttcaga gtcaaattgt cttggcttag gtcagatttc ataccgcacc tttactgctg
     1501 agcaggccaa ccaattgact tatgttgttg gaaaatcata agtaatcttc ttgctttaaa
     1561 ggcgagaagt acagaatttt tgtaagaaaa aatccagctc tgttgcaggg ctgttttttt
     1621 ctttgcttta ttgtgaaaaa aatctcaaat tcaatcttga caaaggcttg acaacataat
     1681 aaattaagtg agattaataa aataattaaa tggctaataa catttttaga aggttcgaaa
     1741 taatgaaaag tatcaataag tgcgccattc ttgctttatc aacgctggct cttgcccagt
     1801 ctgcccagac ggttcgctca gaggctactc aagtctcttc aagtcttgtg acgactgtca
     1861 agcttaagga taatatttta ttgttcgagg agatcggtcc ctatgcggac aagtcagagg
     1921 ggaagctcta ttataaaaat atcgagaaaa ttctcattga tggtaaagag tatgacaaaa
     1981 agctggaggg tgactatagc tatgacatca attaccaagg aatcaaggta aacgctaaga
     2041 acatcacaga aggacagcat cagctgcgca tcgtcaataa gactaacgga ggcattcttg
     2101 tggtctttga caagaaagga aatgatgtta cctttgtttc tgccaagcct tcagatgata
     2161 ctactgcttc accgcagcaa gctgctgcta agacagaaaa gcctgctaag gtaactagcc
     2221 atgatggctt agcgacccta tcatttatca ccaaactaga gacaacagaa ggagagcttc
     2281 tttttccgga aattgatcgc tattccagca ccaagcaaat taaggaatta gctcatcaaa
     2341 tcacaaagat caaggtcaat gaccaggact ataaggattt ggtctatgat tcagtaaagg
     2401 acaagcctgg ctatgtgtct gacctgaagg ggcttcatct tgggacgaca gctttcaagg
     2461 agggagaaaa caaggttgtc atttcctcac aaagctttga agatgtcatc attacagtga
     2521 aaaagtcagg ggagcaatac acctttgttt ctgctaagca aaagcagaga caaggatccc
     2581 agcaggaagc accgcaggga cttgatttta ctaagctgga aagcgcgatc aaggaagctg
     2641 agcgtatcat tgctagcgag gccaataaag aacaggtcaa ggacttgtct agcaagcttc
     2701 aggtgatcaa ggagtcctat cgtcagattg acaatgaaaa attgctcaag gagacctatg
     2761 agcttttgat ggatagtatc aagtcctatc agggaactga tctggctgtt acggatctaa
     2821 aggcaggaac ctatacctta acctttaagg ccaataagga aaatacagag gaagcctcaa
     2881 tgctgcaggg agcatttgat aagaaggcca agctggtcgt caaagaagat ggcaagatgg
     2941 agatttcatt gctcaataca gctctagggc aatttttgat tgacttttcc attgagagta
     3001 aagggcagta tccaacctct gtccgcactc aggttggtga acgcgatatt aacaataact
     3061 acattagagt gaatttaccc taccgattga ggagctggac aagcttcaca agggtgctgt
     3121 gctagtatca gctatgggtg gtcaggaaag cgacctacat cactatgaca aatacaccaa
     3181 gttggacatg acctttagcg ctacagcaag taagggctgg acaggctatc aggctgagat
     3241 tgacgacaag gaaaaagggg tcggctctga gcgtcttgaa aaggttttgg ttaagcttgg
     3301 taaggacctt aacggtgatg gcaaaatgtc acctgaggaa attgcgaaga ttgaaggtga
     3361 gctgcgccta gaccactatg atttgacaga tatttcactc ttaaagcatg ctaagcatat
     3421 tactgagctg cacttagagg gcaatcagat tgcaagcatt ccaaaggaaa ccttcagtca
     3481 aatgaccaat ctaaggttct taaatcttcg cagcaatgtg attacaaccc tagataagga
     3541 tacctttgct cataacagcc agctaaaaga gctctatctc tcaagcaact atatgccaaa
     3601 tctggaggaa ggactattta gaaatcttgg tcagctggat cagctagatc tgtcaaaaaa
     3661 tagaatcagc gtgattcgag atggtgtctt taatggtcta tctcgcttga cctccttggc
     3721 cttggctgaa aatatcatta ctgaattttc agaaaatgct ctagcttcac ttgataatct
     3781 aaacttcttt gatgtttctg aaaaccagtt gggcagcctg ccaagctcct tgagtaagct
     3841 aactaagctt tcttatatcg ttgccaatcg aaaccaggtt ttagatattg ctaatattga
     3901 ctttagtcat atgccaaact tattaaccgt tgacttggca tcaaatgagc taactaaaat
     3961 cccacaggga gccttcaagg ctaataagca gctatcaaag cttaatgtct ataataacct
     4021 tttaacgaat attagcgaag ctgattttgc agatctaaag gcattggatc ttgatcttaa
     4081 gtttaactgc ctaagtggcg ttagtgataa gcttagacag atcatgggaa caaataagct
     4141 aaacccacaa aagcaatttg ctaatctatc tgcgacttta aatcatcaag cgatgaccta
     4201 tcaccaaggg tttagcctgc ttgatttgta ttattgggag cagcagacac tctcaagcac
     4261 cgaagcagaa attagctctg ttgaggatta caataaacgc cttaaggcaa gctcgtcaga
     4321 catcattgcc ttattaaatg agcgttatgc tgactgggat attgtggtgc aattgcagaa
     4381 aaaaacatca accggtcaat atgtcaccgt tgatgagaga cgcttgaata acgatccaca
     4441 agatgagctt caaggctcct ttgacctaaa gggagcaggt gtttatcgtg ttcgtaaggc
     4501 tcttatcacc aaggaatttg ctaagaagcg tgagcatatt tatctgacct ctaatgatgt
     4561 tgaggtcaag gaggatcagc ttgcaggtag tgaccagtct aagggcttgg atattaataa
     4621 gcttgaagat ggtgtctact acatcaaggc aagcatgctt aaaaatgatt tgcagtcaga
     4681 atcaatgtct catcaggcta ttgaccaccg cgtcaaattg attgtgaata agggtgtcta
     4741 tagcctagag gtgaccttta agggcatgaa gatcggtaac ctgacagggt atctcggaga
     4801 gttgagctac tttgttgatg gctaccaaag ggatttgact ggcagaccgg ttggtaagac
     4861 agaaaaagca gaggttgtgt cctactttac agatgtcaca ggcaagcccc tgtcagacgc
     4921 ttatggcagc aattacccac aggtgttgag atttaggctg attgatcagg ctaaaaagga
     4981 tggcttggta cctcttcgcg tctttgtgcc aattatggac gctatctcta agggaacagg
     5041 cttccagaca gtctttatga agttggatct tcaaagcctg acaaaggata aggcacaatt
     5101 gccacactca gaggacaatc agggacatgg taccataggt gagctcttgc agcctcacac
     5161 aggtatcatt ggtggtcata caagtcctgc tattcctaat ttgaccaatc ttttgactaa
     5221 gaagtcagct gctccaagca gtaatgccaa ggaggacgct aagaccggta cagataagct
     5281 taagagcctg atttcttcac ataaggcgtc taaggctggt acaggcaagg cctctaagca
     5341 ggctgctaag actagagcca aagctaaatc taaggctgct aaacatagtc aggagcagat
     5401 gaaagctgat catcgcggcc atatcattat cggtctagca agctttattg tcatagcagt
     5461 tggtctcatt cttggtagga aaaaattatt ttaagtcagt agagagtctg tttgatgcac
     5521 taagagcttg gtttaatcgc ttgtagtcat caaggcttat caacgatacg taaaggcatg
     5581 cctgtttcta atgatttctt aagcttaccc ttggtaagtg aggaatgggt atgcttttcg
     5641 tatttgaggt gttataatag tcaaataaga gtaggtcttg gcctgcgtct aaatctatgc
     5701 cttatttgat tgtcgtaagg aaatgaagat cattaatgag gaacatatga taaagagatt
     5761 attcaaaaaa ttaatgggtg gcttggtggt attgctggtt tgcctagcag ctataggagg
     5821 taaggcctat gctgataagg gtgagcttta ttcctgtgtg attaggcgag attatcgtca
     5881 cccggtttca gggcaaattg aagatagcgg tggtgagcac gcttttgaga ttggccaagg
     5941 tatggtggaa ggaacagttt atagcaatgg tatgctagag gtaacctcgg ctggggattt
     6001 gtatctgacc tttcgcatga gtctagctga tttttcaggt aactaccaat tttgggttca
     6061 gccgggtggt acaggggctt ttcaggcggc agcctacagt gtcaccaagg ttggcactga
     6121 taccaatggc acaacaaagg atattgcgat tgctttgcct gatgtcaata cggttgttag
     6181 aggcagcatg tacgtagagc ctatgggcag agaggttgtc ttttacctgt caccatctga
     6241 gctacaagaa ggctacagtg gagatatggt agctagcttt gcagcaggag aagccaagac
     6301 ggatcatgcg gtgacagctc ctgcaaaggc agatgagaag aaagctccta gtaaaccgga
     6361 ctcaaaagac gccaagtcag ctcctaatcc ctcagcaagg ccagttggtc aatcaagcag
     6421 tcccaaaaaa cagtcaaatc cctctaagaa gggtcaggca gttggtttga gcacttcgct
     6481 agataaaagt aagcaagagt cgtcccaaaa gccagtaaat aatccattgc cagttctggt
     6541 ttactatgta ccaacagctc ttttgttgtc aggagccttg gtcttgttta taaagaaaaa
     6601 gagaaaaaac aatgaagaaa gtcattaagc ttattggatt agctgttttg tccttggtgc
     6661 tatctgcttg tgtggatcag caccctaggg cagagaaaaa ggctgataag gagagaattg
     6721 ttgccacctc tgtggctgtt gttgatattt gtgatcggct aagcctagat ttggttgggg
     6781 tctgtgacag taagctatac caattgccaa agcgttacga tgctgtcaaa aggatcggtc
     6841 tgccgatgaa tcctgatatg gaggttattg cttctctaaa gccaacgtgg atactcagtc
     6901 ccaattctct gcaaaatgat ttagagccta aataccagca attggatacg gaatatggct
     6961 ttttgaattt aactagcctt gaaggcatgt accagtcgat tgatgatttg ggggacttgt
     7021 ttgatcgcaa aaaggaagct aagcgcttgc gggctgatta tgaggagttt taccgggcct
     7081 ttaagaaaaa gcataaaggg caaaaaaagc ctagggttct tattttgatg gggcttcctg
     7141 gcagctatct gattgctaca aataaatcct atgttggtaa tctgcttgag ctggctggtg
     7201 gtgagaatgt ttatcactct gaggacaagg aatttttgtc tgccaatcca gaagacatgc
     7261 ttcagcagca gcctgagctg attttgcgta ctgcccacgc cattccagac aaggttaagg
     7321 acatgtttga taaggaattt gctgaaaatg atatttggaa gcattttgaa gctgtcaagt
     7381 ctcagcaggt ttatgattta gacaataccc tttttggcat gagtgctaag tttaactaca
     7441 aagaggcttt gaaccatctg tcacaaatct tttatggagc aaaggaagtc aagtaagatg
     7501 cagcaaggta gtcaatattc tgatcaagtc acagcagcaa gaaaaaggac cactagactg
     7561 gtctatatgg ttctattgct catgctgctg tttggtttaa tgctatatgc ggtctctgtt
     7621 gggggcttat ctgtttctta tcagaggatc tttaatggct tatttgtagc atatgattca
     7681 gaggtagccc ttatttacga tttacgcttt ccaaggattg tgattgcttt attggctggg
     7741 gcggggatag caacatctgg ggtcttgttt caggcgattt taaaaaatcc tatttcagat
     7801 ccggcgatta ttggggtttg cagtggggct agctttatgg tcttgttatc tagcctgctt
     7861 ttgccgcagc tcttgtttta tggtcctttg ttatcatttg tgggaggctg tgtttctttt
     7921 ttgatgattt ataccttgtc ctggaagaag ggcttgcagc cgatacgcat cattttgaca
     7981 ggaatagcta tcaacgcctt gtttttaggc ttgtctcgtg cgattactga tttttcaaaa
     8041 accagcaatc cctttgtcaa tgcgctgttg tcaggaaata ttagtcaaaa aacctgggca
     8101 gatgttggtg tgctgtggcc ttatacagtg cttggcctgc tgcttgcgat aggcctagca
     8161 aggcagtgtg atctactgct gctaaacgat ggcttgattc gtaatttagg cattgatagt
     8221 aattacctgc gcttaggaat ctcgttggtt gcggtcttac tagctgctgt ttccacctcg
     8281 attgtgggtg tggtgtcatt tttaggcctg attgtgccgc atattggccg ccttttagtt
     8341 ggcagtaagc atagctatct cattcctttt tctgccctgc ttggcgcctt tgtctttttg
     8401 ctggcagata ccttaggaag gcagttgtgt tatcccttgg agattagccc agctgttatc
     8461 atgagcattg tcgggggacc ttattttatt tatctgttaa ggaggtctga cgtgatatga
     8521 gtcatgagca aggcttgatt cgtgtagagg atttgtcctt tacttatcgt gataggccta
     8581 ttttagatag gctgagcttt accattccaa aaggcaagat aacgacaatc atgggggcaa
     8641 acggctgtgg caaatcaacc ctactaggtc tgctgactaa aaatatcccc gttaagtctg
     8701 ggcaaatttt cttagaggga caagctatta gctctattag tcttaagcag tttgcccaaa
     8761 aagtagccgt tgtgcatcag gataatcagg cggtagcaga tcttctggtg ggtgatttgg
     8821 tggctgtggc aagccaagcc catcggcgtt tttttaaggg atcaagtcaa gaggacgatg
     8881 acattgttgc ttgggcctta gaggtgacta atctaaggga attggccttt agggaaatgc
     8941 aggagctatc tggtggtgaa aagcaaaggg tctggattgc tatggcgctt gcccaaaaaa
     9001 caggtgtctt agtgcttgat gagccaacca cttatcttga tattaagtac cagctggaca
     9061 ttttagccct catcaaaaaa atcaatcagg agctaggaat gaccattatc atggtgttac
     9121 atgatattaa tcaggccttg gctgtttcgg attgtgtgct tgggctgcaa aaaggtgcca
     9181 tctatgccca aggcagtcca caggaggttc ttgatcaggc ttttgtggag gcggtttttg
     9241 gggtgagctt gccctttatt gaaaagcagg ataggcgatt tgttcttacc actttatgag
     9301 acaaataaaa aatgaatgat agataggaat aaggcgacga ttatatgaac gatacaactg
     9361 aaaaaatatc acgcgcaaag aaaaaaatgc ttttaaggcg tttaaaggag cgtattgctc
     9421 ctaagcgttt tttgctttat gtgtcggcct ttttatcttg gctgcaattt ttgatgcgtt
     9481 taatgagctt ttacttaatt gctaagcaat tcacagcctt tttagcaggt caagccctgc
     9541 aattgacaag gctgcttgtt atccttttga ttttaaatgc tgttggcttt ggcttggcga
     9601 tgattgcaaa gcagctgcag ggcctagctt cgcaatttgc gcgtgactcg ctcaagcaat
     9661 ccttttttga tgcctttatt gctatggacg ggcaatttga tcagcagtca acagaggctg
     9721 atgtgttaac ggttgcctca caagggattg atagcttgga tacctattat tcctattacc
     9781 tatcgcttgc aatgctaaca gcttttaatt gcacaacggt cttactgctt gtttttttga
     9841 tctatcctat agggggcttg gtctttatct tgtctttgcc cttgattccc atatccattg
     9901 ttgctatgca aaaacgctct aaaaggatca tgaaccatta ctggtcaacc tatatggacg
     9961 ttggcaatct atttatggac gatctcaagg ggctaaatac cctttattcc tatcaggcag
    10021 atgaaaggta tgaggaaagc tttgtcaata aggcagaggc ctttcgtaag gctaccatgc
    10081 agctcttggg ctttcagctg caagcggttg gctatatgga cgctgtcatg tatcttggca
    10141 ttggcttatc tggcttttta gcggttcagg ctctgtcagc tggtggtata tccttttttg
    10201 actttctctt ttttatcctg attgcaacgg aattttttgc ccctattagg gagcagggct
    10261 atggcatgca cctagtcatg atgaatacta aaatggcaga tcaaatcttt ggctttttag
    10321 atagcgttga ggctgttgac caagacaagg gagttgcctt accggccttt gatcgtattg
    10381 atattcaaga tttgtccttt tcacatgggg aaaaggcttt gctaagagac atcacgatga
    10441 ctatcaaaaa gggtgagcta acagctgttg caggtgtttc aggacagggt aagactagtc
    10501 ttgcacagct cctgttgaag cgctatcagg cagatagcgg tcagatattc cttggtgatg
    10561 tgacgattga tctggcttct aaacaggcca tcaatcagga aatactctac gtttctgacc
    10621 agtcaacgct gcttaatatg agtatttatg agaaccttgc tatggcagct cagctgacta
    10681 gaaaggagct gcttagctgg attgatgagc atggcatttt gagctttatt tactggctac
    10741 ctgatgggat tgataccatt gtaggtgaga atggctgtca cttatctgca gggcaaagac
    10801 agcaggtgat ttgtgctagg gccttattga gccagcgttc ctgttatatt tttgatgagg
    10861 ctacctcaag tcttgatgct gagaatgaag ctgctattca cagactgctt cagcaattgg
    10921 ctaaacaggc cattgtaatt gtcatcactc ataagatgaa atatttgaag caggctgatc
    10981 aggtgctctt tttaagccct gagcagtctg ctagcttggc tagcccaaga gagctttacc
    11041 gccatcattt ggcctatcgt caattagttg atacacaagt agaattggag gcaaatcttt
    11101 atggttaaga gtgattacag cacctaccgg ctagttttac gattgcttgc tatgatgaag
    11161 catttgctgg cttggatagc tctggcggtg atgtttgcag tgctgggctt tgtgcttacc
    11221 gttggcattc ctaccagctt agcctatctg ggcttagagg tgatggctgg tcatgctatt
    11281 acctttaaat ggctttatct atttgttgct atggcactgc taagggggct tgttcgttat
    11341 ggagagcatt attttgggca ttttgttgcc tttcatagcc tggcagcctt tcgcaggatt
    11401 gtctttaaaa agctaagagc actctcgccg gcacgcttag acagtcagga cagcgggcac
    11461 ctgttaaaga tgattggcga ggatattgag gccttggagg tcttttttgc ccacacgctt
    11521 gcccctattt gtacggcgtt tatttcagct agcttgatgg cctattacct ttggcaggtt
    11581 agctggaagt tagccttggg ggctattgtg acctatgtgc ttttggctgt tattattcca
    11641 gtgtattttt caaacgtcct tcaatcactg ctcaaaaagc aaaatgaagg gcgcagggct
    11701 tatgtgtcaa gctttttaga gagtctcaga tctgttaagg atttgctgca atttcaaagc
    11761 attgagaagc gctttaagct cttatccaat cagagcaagc atgttaatgc gcttgatcgt
    11821 caggtggcac aggctcaatt tttacaaatg gcgataacct ttttggctct tggcttgtct
    11881 attttgacct ttgcttatgt tactcttttt gagctgagtc agcagacggt gacgtttgct
    11941 ggtgggttgc tggcttttgt tgcctttaca gcctcctttg cacccttttt agaattgggg
    12001 cgtttgccgc ttggcttcaa gcgtgccatg aatgctgcta ggaatgtctt tcagctttta
    12061 gatgaagaag cgttagtaga taagggagat cagcgtattt cctcggtaac aaggattgct
    12121 gttgaggatc tgacctttgc ttatcccaag catcaggaga ctatttacca ccacttatcc
    12181 gtcgcttttg aaaagaaagg cattatcggt attcagggag agtcaggctc tgggaagtca
    12241 actctgatga agatcattat gaaatggtac aattggcaag ctggtcatat tttcctgagt
    12301 gaggttgaca gtcaaacgct aaatgctgct tccctacagg ctaactttgc ctatgtccca
    12361 cagaatgcgc agctatttca gcaaacactt cgtgacaata tcacacttgg tcgtaaggac
    12421 atttcagatg atgatatcat ggaacttgct gaggcctgtg gcatgaagga gcgtatccta
    12481 gcctgtgatg aggggctaga taccctagtg agaggatcag cagacttttc agctggtgaa
    12541 gcccagcgct tggaattgat gcgggctcta ttgaagcggg cggattgcta tatttttgat
    12601 gagccaacat caaacttaga ttcgctgaat gaagccatct ttattgattt gattaaaaag
    12661 cattgccggg gaatggtctt tttgatttca catcggccat ccaccttggc ctgtgcagac
    12721 cagctatttt gtgtgagaaa tggttttttg aaggaggtaa acaatgaaag ggttaaccat
    12781 taaagatatc atgacaacag gcgcctttgc cgccctctat ttcgtttgtg tggggctagg
    12841 agccatgctg agcattctgt ttgatcgctc aggcaatatg ctctatgcgc cagcctttgc
    12901 ggccttgctt ggcgggccag tttatatgct attaatcgct aagctgcaga cctttggacc
    12961 gataagccta gtaggaatta ttatgggaag ctttttcttt ttgacaggtc atttttttgc
    13021 ttcaatgcta ccagctattc tttttggctg tttggcagat ggcatagccc ttttaggaaa
    13081 atatcaatct agactagtga atctcttgtc ttatcttgtt tttgcctttg ttaacagtgg
    13141 tcctattatt ttaatgtggc tgttgaagga cgcctatatc cagagtcttt tagcgcgtgg
    13201 taaggacatg gcatatgtta accgtatcat gtatgacttt accgttgcaa atgtcagctg
    13261 gtttgttggt gttgtccttc tttgtgcctt agtaggtggc ctttttggtc aatacctgct
    13321 gaaaaagcat tttgctaagt caggaatgct tttatgaggc ttgatgttcg cacaaaattg
    13381 ctcctgttaa ttctagccaa tgcctgcttc ttttttcgga ttgatggctg gctggggacg
    13441 atgattatag gtgttttgct tggcattttg ttttggcttg gtcaagggcg tctggcaatc
    13501 ggtatgacac tgctctatgc cttactgctt gctttgtctg tattgccgct tcatgtgctg
    13561 ccagcctatc tgtttaggct gctgagcttt gcagctgttg ctggtcaatt gctttaccca
    13621 tctgtgcttg ctgctttgat ttttgtcaag acaacgactg cctacgagct tgtgcatggg
    13681 ctgcgaaaat ggcatgtgcc agaggtttgt ctgttgactc ttgctgtcat gctgcgtttt
    13741 ttacctaaga tcaggcaaga aggaaagatt attcggcaat ctctgaaaat caggggcatt
    13801 ttcttggaca gctgggctat tgtcagacag ccaaggcggt atatggagta tctcttggta
    13861 ccgctgttga tgtcattgct gagaagtagt caggacttaa ccattgctag cctaacaaaa
    13921 gggctagcaa tcaaaaaggg agcaagtgag tgcttcgtat cacatctatc atggaaggat
    13981 tggggggtac agatttggat atttgtgacg atagcctaca tggttctcca gtgatcaagg
    14041 caaagcagct gcagttttcc tataccaatc gtaggcagac tgcctgtgag ctcagggatt
    14101 gtcagataga ggcaggtcaa tttatcgtgc tttgtggtca gtcaggctca ggcaagtcaa
    14161 cctttcttaa gctgctcaat ggcttgattc cagactattt ttcaggacaa ttacaaggaa
    14221 gtctgaaagt actgtctcat caggctggtc aggctagtgt tgaagtgctg tcaaggcagg
    14281 tttcctctgt ctttcaaaac ccagccagcc aatttttcta tcgtgaggtc aagcatgagc
    14341 ttgtttttcc ttgtgaaaat caaggcttag agccagctct tatccttgag aggctggata
    14401 ccttggcagc tgattttgac atcaaggact tactagaagc agatatgctt aagctatctg
    14461 gtggtcaaaa gcagcgggtg gctattgcag cagctatcat gcaagggaca gctatcatgg
    14521 tttttgatga gccaacagcc aatttggacc atgctagtgt agcagcggtc aaggcttatt
    14581 taaagcagct taaggctgct ggcaaaacca ttattgtcgc tgagcaccgc ttgcattatt
    14641 tgctggattt ggcagaccat ttttactatt tttcagctgg taggctagag cgcgtattaa
    14701 gccccaagga tctgctagct ttgccagatc aggaacgtga ggagctagga ctaagacgat
    14761 gtgagttgac tgctgtgact aaggctttgc gggcaaaaac tgtttttgag cattatgatc
    14821 cagagcatgc cttgcaaatc aagcagctag aggtcaaggc aggcagcagg gttttgtatc
    14881 acctcaatca gctcagcttt ggtgcagggc aaatcactgg cattaccgga gctaacggtt
    14941 tgggaaaatc gcagttggct ttatatctgg caggtatttt tgaagcaaaa gaggccaaga
    15001 tcagctatct gggtgtcacc ctgcctgcta aggacaggct ttcaatcaca agcctagtgt
    15061 tgcaggacgt tgggctacag ctattttcgg agacggtaga aaaggagctt aatctaggtc
    15121 atcatagaca tcaggctact gatgatttgg tgaataggct tgggctttct cagcttctag
    15181 acaagcaccc tgccagccta tcaggtggtg agcagcaaag ggtgatgatt gctgccagcc
    15241 tcttgtctga caaggagatt gtcattcttg atgagccaag cagtggctta gatctgctgc
    15301 aaatgcaggc tctggttagt cttttaaagg agctaaagca gcaaaaaaag gtagtgattg
    15361 tcatctctca tgacgaggaa ttactggatc aagcctgtga tagtatctat cagttgagca
    15421 ggtaaaggcc tagccttgct caagcggtct ggtgctgtat tggtgatggc tttatcgctc
    15481 cttggagcag caggtgttcc tgcttgatct gataaccact agctgcgatt gaccaatcac
    15541 aagccgccaa ctcttgacaa gctagcagta gctatcacaa ttctagggca tatcttggcc
    15601 tagcaagcag tgctgtattg tttatatgcc actcttcatc ttttagttag gccgtcctag
    15661 cggccgcact aagggtgtgt taggatcggc taatacctca aggcatctac agtaagaaaa
    15721 cgagcctctt cctttttgga gaggctcttg atttttgata taataatgaa aaagaaagcg
    15781 aggttgagat gctgttaaag agttcgattg ctaatttgaa gggtcttggt ccaaagtcag
    15841 ctgagaaatt tcaaaaatta ggcatttatc agatcaagga cttgctactc tattatcctt
    15901 ttcgctatga ggattttaaa agcaagtcag ccttagagct tttagatggt gaaaaggctg
    15961 tccttacagg tagagttgtg actccaccaa gcgttcaata ctatgggttc aagcgtaatc
    16021 gcctgagctt taaattgaag cagggggagc ttgtgattag tgtcagcttt ttcaatcagc
    16081 cttatctgct tgagaaaatc gtcttggatc aggaagtggc tatctttggt aggtgggatc
    16141 aaaaaaaagc agccttgaca ggtatgaaat tgctcatgac cttagaagat gatttgcagc
    16201 cagtttatca tgtggcgcag gggatcagtc aacccaccct gattaaggcg atcagatcag
    16261 cctttgatag cggtgcctta gctcagctgg aagaaaattt accagagccc ttgattcaga
    16321 aataccgcct gctgccgaga caagctgctg tttatgccat gcattttcct aaacatatgg
    16381 aggattataa gcaggccctg cgccgtataa aatttgaaga atttttctat tttcagatga
    16441 atctgcaggt tttaaagctt gctaacaagg cagagggcaa tgggttagcg attccttttc
    16501 atcagcaggc agtggcaaaa aagattgctg ctttgccctt ttcactgacc agagctcaac
    16561 aaagaagcct ggaggaaatc ttagcagata tgacctcagg ggctcatatg aaccgtctgt
    16621 tgcaggggga tgtcggctct ggcaagacag tgatcgcaag ccttgccatg tatgctgccc
    16681 aaacagcggg atttcaatcg gcactcatgg tgccaactga gattttagct gagcagcatt
    16741 acgatagtct ttgtcagctc tttccagatt tgtctattgc cctgttgaca tcgggtatga
    16801 aagcagctga aaaaagagca gctttatcgg ctattgctga tgggtctgtg gatatgattg
    16861 ttgggacgca tgccttgatc caagacgcag tgacctatca taagctaggg ctggtgatta
    16921 ctgatgaaca gcaccgtttt ggggttaatc agcgtcgctt gtttcgcgaa aaaggcaaca
    16981 atccagatgt tttgatgatg acagctactc ccatacctag aaccctagcc ataactgcct
    17041 atggtgagat ggacgtttcc attattgatg aattaccggc agggcgaaag ccaatcatca
    17101 ctcgctgggt caagcatcgg caattagata gtgtgctggc ctgggtaaag accgagcttg
    17161 ctaaggggac acaggcctat gttatctctc ctttgatcga agaatctgaa actctagatt
    17221 tgaaaaatgc ggtagcttta gaggctgagc tgaaggatta ttttaaagct tcagctagtg
    17281 ttgccttgat gcatggcaaa atgaaggcag acgacaagga gatgatcatg cagcgcttta
    17341 aggctaagga gattgatgtc ttggtgtcaa caaccgttat tgaggttggt gtcaatgtgc
    17401 caaatgccac catcatgctg atcatgaatg ctgaccgctt tggccttagc caattgcatc
    17461 agttgcgtgg tcgtgttggg cgaggcagca agcaatccta tgctattttg gtggcagatc
    17521 ctaagacaga ctcaggcaag gagcgtatga ccatcatgac aacgactaat gatggctttg
    17581 tgctggcaga ggctgacctc aagctgcgtg gctcaggaga gatttttggg acccgtcaat
    17641 caggtttgcc agagttcaaa acagctgata ttgtagagga ttatcatatc ctagaggagg
    17701 caagacgagt cgctgctgag attgttgcag ctaaggattg gcagctggac cctagatggg
    17761 ctccgatttt ggctaatctt cgtgtcgctg atcagtttga ttagatgtga ggctgacttg
    17821 ctggacagag ctaatataaa aacacgacaa gaggttctta gctgaccgag tcgtgctttt
    17881 tgtgctatag atgaggagta gtagcctgtg attataggag agcttagcct tcgatataat
    17941 ccttcagctc ttgacctgta agcccagcgt tgagggcgat gagcaatttt aacctggcct
    18001 taggggcatt tagctccttg acaaacataa caccagccct ttttaagctg gcaccacctc
    18061 cgcgataagc ataaactggc tctgctatgc cattgaagca gcgcgagacc aagacaacag
    18121 gaatcccaga ggcgattaat ttttcgagct cagatactgc taggggagga acatttccag
    18181 cgccgagggc ctcaatcact agtccctgaa tcctatcagg tgtcaaaagg cttaaaatac
    18241 ttccatctcc cataccagca taggccttga taatcggaac tgtgccagaa atatgacgaa
    18301 gctcaaagcg aacccttggc tcagcagtct taaagaacag taaatcgtcc ttcatgacga
    18361 ctcccaaagg gccatgagtc ggtgtttgaa aggtcgaaac attggtggta tgcgttttgg
    18421 tgacatactt agcggcatga atttcatcat tcatcacaac cagcaccccc ttgcccttgg
    18481 ctttctcatg gctggctacc ctaagcgctg ttaggtagtt atagatacca tcgcttccaa
    18541 tctcgttggc cgagcgcata gcacctgtga taacaatagg caactctaca ggcagcacca
    18601 ttgtgtctag aaaataagca gtctcttcta aggtatctgt accatgtgtg atgaccactg
    18661 catcaaactg actagccctt tgttgaatgt aatgatacat cttgagcatg tggtgagggg
    18721 tgatgtgcgg gcttggcaga tttaaaaaat ccacaacagt taggtggata tgctccaggc
    18781 taaggccaac ctgattcatt ggattgtttt gatttgggct caccttgcct gcttcatcag
    18841 cctgcattga aatggtgccg ccggtatgta agacgaggat ttccttcatt tgatactcat
    18901 acttctttca atttatgata taatttattt tatcacaaat agaagagaga acagaaggat
    18961 ttgacaataa aagcagtctt tttcgacatt gatggaaccc tgcttaatga tcgaaaaaat
    19021 gttcaaaaaa cgacgcaaag ggctattcag caattaaaaa aacaaggtat tatggttggg
    19081 ctggcaactg gtcgtggacc tgcttttgtg cagccctttt tagaaaattt tggcttggat
    19141 tttgcagtga cctacaatgg tcaatacatt ttgacacgag acaaggtctt gtatcagaac
    19201 cagctgccaa agtcaaccat ttataaaatc attcgctatg ctagcgataa aaagcgcgag
    19261 atctccttag gaacagcttc aggtcttgct gggtctcgga tcattgatat gggaaccagt
    19321 ccatttggtc agatggttag cagtattgtg ccaaggagtc tggtcaagac ggttgagggc
    19381 agctttaaaa acctcatcag acgctttaag ccgcaaagct tcagcaatct tgttaccatt
    19441 atgagagagc cgatttatca gattgtcttg gttgcttctg ttgatgacac ccaaaaaatc
    19501 aaggaaagat tcccgcatat caaggtaacc agaagcagcc cttattcctt agatttgatt
    19561 tctagcgggc agtctaaaat caagggcatt gaacgcttgg gcgagatgtt tggctttgag
    19621 ctctcagagg tcatggcctt tggcgactct gataatgact tagaaatgct ctcaggcgtt
    19681 ggtgttggtg ttgcgatggg aaatgctgag gcagtggtta aaagcggtgc tcactttaca
    19741 acagcttcaa ataacaatga tggtatctct aaggcgctgg cgcattatgg cttgattcat
    19801 tttgatgtgg aaaaaagctt taaaagtcgc gatgataatt tcaacaaggt caaggatttc
    19861 caccgcctga tggacggaga cacgattgaa acaccaagag gctattcctt aaaggaggct
    19921 ggctatcgag cagattttaa ggtagaggaa cttgtggaat ttctttatgc agccagtcaa
    19981 ggggataagc atcgcttttc tcaggctttg atagacctcc atgctgccct tgataaggca
    20041 gctaagaagg tgcaggccaa ggagcaccca gagtcacccc tggttgggca ggttgatgct
    20101 ttgacagatc tgctttattt tacctatggc tcatttgtat tgatgggagt ggaccctcag
    20161 cccatttttg agaccgtcca tgaagccaat atggggaaaa ttttccctga tgggaaagcg
    20221 cattttgatc ccataacgca taaaattcaa aagccagatg actggcagga gcgctatgca
    20281 ccagagtcag ccatcaaaaa agagttggac aagcagcttc aaaaatcatt gcagcgcttg
    20341 gaaaaataag gctgtcttta ttttagaggc attaaaaagc accttgagct gtgagttgat
    20401 ctcctagctg ttaagcattt ggcctaacac ttggggtcac ttcacttatt agctcagggt
    20461 gctttttgat gtagactaga caccctcaat aaaagggccc ttaagtctag ctagtggtaa
    20521 ttagtatatg agagcagtag tcctttagta gccttgtgag ctgaggctaa gggctaggta
    20581 tggttacttc acttaggctg caaatgcttc tgacagctga gagaattcgt cttgctacag
    20641 ggttttgtca tgctctcgaa ccactaatag gtcaaccttg gcatgacgaa ggatatattc
    20701 agatgatgat ccaatcagca accgctcaaa ggtgttaagc ccagttgccc caaccataat
    20761 caaatcaacc tcttctttgt cagggatatc gtgcgctaat agcgttttgg gattgccaaa
    20821 ttcaatcacc tgcttgacct cagtcagccc tgcctcgcgt gcttgttttt caaaatcccc
    20881 caagacctct ttagctt
//
LOCUS       DARYNN010000037        20223 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.037, whole genome shotgun sequence.
ACCESSION   DARYNN010000037 DARYNN010000000
VERSION     DARYNN010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20223)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20223)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20223
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.037"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            <1..1230
                     /locus_tag="TVB59_001406"
     CDS             <1..1230
                     /locus_tag="TVB59_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEL1010291.1"
                     /translation="FNKHIYDKLYDYDTFTEVHYGGASSGKSHGVIQKVVLKACQDWK
                     HPRKVLFLRKVGATVYDSIFEDVKQCLELWGLLDKCKVNNSAYRIELPNGATFIFKGL
                     DNPEKIKSIKGVSDVVMEEASEFTLDDYTQLTLRLRDRKHLKKQIFLMFNPVSKVNWV
                     YKAFFVKTPKNTVVYQTTYKDNRFLDDVTRENIEELANRNEAYYKIYALGQFATLDKL
                     IFPKYEKKILNKDKLSHLPSFFGLDYGFINDPSAFLHVKIDDNNKKLYILEEYVRKNL
                     TNDKIANAIKDLGYAKEEIRGDSAEKKSNQELRNLGIPRIIDVKKGPGSVMQGIQYLL
                     QYDWIVDERCVKTIEELENYTWKKDKKTNEYINDPVDSYNHCIDAIRYATSNHFLTLD
                     KKQSNSFNIFRKAGFGL"
     gene            1242..2744
                     /locus_tag="TVB59_001407"
     CDS             1242..2744
                     /locus_tag="TVB59_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000930109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEL1010292.1"
                     /translation="MLYTETFKDSTGNAKLLEFRFHRESRMRYQTSDLSGLFDEGYKL
                     LLDYIKHHESKQKPRIQELLDYAEGNNHTVCESGRRREADMADSRAIHNYGKYISTFK
                     QGYLVGNPIRVEYEDNDDAKKQLFKELADKNNFHQLNRRLVKDLSKVGRAYELIYRSM
                     DDKTEVVRLDPRETFIIYQADVGQASLVGVRYYNKSQLDRTKKTVEVYTDNEIIYFDY
                     DGQLTEVDRRPHIFKSVPITEYLNTDDGLGDYETELSLIDLYDAAQSDTANYMQDLSD
                     AILAIIGRVSFPSYVDTKEKAIEYLRAMRKARLLNLEPPVDTEGREGSVDAKYLYKQY
                     DVNGTEAYKDRVVQDIHRFTNTPDMSDSKFAGTQSGEALKWKVFGLDQERVDLQALFE
                     QSLKRRYKLIARVSELLKEIDGFDISKLKITFTPNLPKSLHEKIEAFKALGGELSQKT
                     TMSITDIVENPDKEIASINDEAKNRSLLAQKMESEGRMTDRELARDYNHE"
     gene            2725..4302
                     /locus_tag="TVB59_001408"
     CDS             2725..4302
                     /locus_tag="TVB59_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head morphogenesis protein"
                     /protein_id="HEL1010293.1"
                     /translation="MTTIMNKSKYWRDRVKKEMDAKEADDISLEQSMKQLHNYHFRNI
                     EKEIESFYQRYADKEKIDIAEARKRVSELDISAYQKKAKELVVKAEKLRKEGKTVTRD
                     DFTHQENADMAIYNLAMKTNALELLRLNIDLEMQELANGEHKLTKTFLDEGYRKEVEF
                     QAGLLGLSVASQASVKGLADAVINANFKGAKWSDSIWDRQDKLRSIISQSVQSAILKG
                     KNGLTIARDIRREFDVSVSYAKRIAITEHARVQMEVSRLSMAENGFAMFDIIPEPKAC
                     DVCKDIAKQGPYHMDKWRTGENTPPIHPYCRCAVVGVEEENSSNHESLDKLIKTEYNQ
                     SMKESSTYARNVLSAVSLIEPRITSQIKHIVKQSNGNLQGLDFRLKSLDSLARKISTD
                     SLLDDISPEEAANNINDALRYTAVFKPDNFFDDYHSMKNALVRDGFKIEKVKNTWLDD
                     GPYNGVNTVVSKDNVKFEIQYHTQESFDLKNGKLHELYEERRLPNITRKRKAELDKMM
                     FELSKSLTKPNQIERVN"
     gene            4304..4510
                     /locus_tag="TVB59_001409"
     CDS             4304..4510
                     /locus_tag="TVB59_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010294.1"
                     /translation="MITKYFFIKTEHPKIVRYSNGLTEVYNSAKGWEEQEAWYDRLFF
                     SDFSDFEEVTEKEAKMFIAGLTAA"
     gene            4507..4926
                     /locus_tag="TVB59_001410"
     CDS             4507..4926
                     /locus_tag="TVB59_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEL1010295.1"
                     /translation="MSIVELAFRVAKKAHLGQVDKAGVDYIKHPITVASFVKTDEEKA
                     TAYLHDVIEDTSLTLLDLEEYDFPRSVIEAVDILTKKKGQDYQSYLNLVKTNKLARTV
                     KLADLKHNSDLSRLSEVTNKDLKRYKKYQEAIKYLNN"
     gene            5123..5392
                     /locus_tag="TVB59_001411"
     CDS             5123..5392
                     /locus_tag="TVB59_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010296.1"
                     /translation="MNKRIKKKRKLETVVVMLVAENALQAEALINQNKEIMELKSIVE
                     RNALATNEELATVKDTVLDNQSVIKAIGDTVDYIKQNYKRKWGKK"
     gene            5428..5595
                     /locus_tag="TVB59_001412"
     CDS             5428..5595
                     /locus_tag="TVB59_001412"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010297.1"
                     /translation="MKVKEIAQVFNEYSDFFVVQNGKYLPGDRTSFFLDCELEIKEIS
                     IGIPDCLIIEV"
     gene            5777..6400
                     /locus_tag="TVB59_001413"
     CDS             5777..6400
                     /locus_tag="TVB59_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEL1010298.1"
                     /translation="MNKKLLEKLFKCAPDTGTGSGGASDADSQQSETDGEPSSEDSFK
                     APQSQSELDSYTNKAIQKALENQRKDEAKRIEEAVKAALDKEKDYSKLSEEERQQREF
                     EDSKKAFEAEKAKFEHDKLVVQVEKDLIAKGLPSEFAELLATKDAENALEQVKTFEAA
                     FKKAVADEVKKTVRQLTPSTGAGAISTQTNYGANLASKIAQQSTTLF"
     gene            6411..6791
                     /locus_tag="TVB59_001414"
     CDS             6411..6791
                     /locus_tag="TVB59_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head decoration protein"
                     /protein_id="HEL1010299.1"
                     /translation="MNKRKVTTSKEILHNLEYEAITVTLDSSTVGKKVIPAGTVLAGV
                     SDSVFKDRKQKVKTVANHEVSGESNICGILLTDVDLTDGDKAGACVYRGTVNADKLAD
                     SSIAENFTELATKLPHVVFIKGGK"
     gene            6794..7843
                     /locus_tag="TVB59_001415"
     CDS             6794..7843
                     /locus_tag="TVB59_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="major capsid protein"
                     /protein_id="HEL1010300.1"
                     /translation="MALIHEIITSENIKGFYNAKNENIDKTLGEKAFPPKQQLGLKLS
                     FIKGAAGKPVTLKAAAFDTKVPLRDRMAVELLDEEMPYFKEAMLVKEADRQELNIISQ
                     TKNSDLIDTVLAAIYNDKVTLIAGAKARLEAMRMEVLSKGKIHVASNGVMKDFDYGLD
                     SSQTTKPSVKWSEAETATPLKDIEGAIEKMAERGFVPEAIIMNSKTFSLIKNAKSTLK
                     IIKPMAPDGAAVTKGDLTTYIADELGLKILFKDGMFIGDDGKSRKYFPDGFATLVPNG
                     NLGYTVFGTTPEQSDLMGGHATDADVSLVETGIAITTTKTTDPVNVQTKVSMIALPSF
                     ERLEEVQIIDSIDQV"
     gene            7854..8120
                     /locus_tag="TVB59_001416"
     CDS             7854..8120
                     /locus_tag="TVB59_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010301.1"
                     /translation="MAEVIKTFRDKETTNTYYVGDDYNGDRIDELTAKGYLSGDKVSA
                     AAIEIDLDKLKVDEIRAKLDELGVAHDPKLKKPELLELLKQSAS"
     gene            8130..8483
                     /locus_tag="TVB59_001417"
     CDS             8130..8483
                     /locus_tag="TVB59_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HEL1010302.1"
                     /translation="MQKINTDSIIANVKLDLGIDDTLQDSLLNMLLKRVTDHFKAEYG
                     VDDIDNAFSFVLEDCLIARFNRRGSERAKSEEVEGHKTTYYDFLNEFEPYDKMIKSNL
                     NLIKDNSRKGGLYFL"
     gene            8480..8788
                     /locus_tag="TVB59_001418"
     CDS             8480..8788
                     /locus_tag="TVB59_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010303.1"
                     /translation="MRYADRITFVKATDEQYDPDLGEYTYTEVMIKTLPCFVMDLGMA
                     KSVQIFGDYQKTRKVVYLRQPYTDLLDHCLYKGKKYKVQVDKQFNTVFYLEGDDSICS
                     "
     gene            8769..9134
                     /locus_tag="TVB59_001419"
     CDS             8769..9134
                     /locus_tag="TVB59_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEL1010304.1"
                     /translation="MILFVADISLKVVGTTGLKNKLELIAKKEAVKKIVRDNGKQLHR
                     KMVQKAVFTKGHSTGATRISITMQIGDDGFSVTVKPGTHYAGYLEKGTRFMSKQPFVL
                     PALKEQKVKFRKDLEALVK"
     gene            9131..9520
                     /locus_tag="TVB59_001420"
     CDS             9131..9520
                     /locus_tag="TVB59_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HEL1010305.1"
                     /translation="MIKTRDQSIFDEMFKRIQSLGFKVYDYKPMTEVPYPFVEMESTD
                     AEYIPNKDDIKGSVDLVLSVWGLQKKRKQVSDMASAIFSQAMSVASSDSFYWSLNIRQ
                     SSIQVLDDTTTVTPLKRAIVTLRFNLR"
     gene            9530..10121
                     /locus_tag="TVB59_001421"
                     /pseudo
     CDS             9530..10121
                     /locus_tag="TVB59_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052382.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail protein, TP901-1 family"
     gene            10183..10542
                     /locus_tag="TVB59_001422"
     CDS             10183..10542
                     /locus_tag="TVB59_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail assembly chaperone"
                     /protein_id="HEL1010306.1"
                     /translation="MQLEIKGKTHNIKFGTRFVAEMDKNHIAEREGMKFGAGLQSTVP
                     FLFERNVVTLAEIIYTGTITESPRPSLNDIYDYIDEAEDIEKLFDDVLDELRQSNASK
                     LFITKLDKNIAEMATEA"
     gene            10584..10913
                     /locus_tag="TVB59_001423"
     CDS             10584..10913
                     /locus_tag="TVB59_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010307.1"
                     /translation="MIVLNCVRYLGMTDINEIGRLTLYEYDLLMIGKALASVDEAYKA
                     HKQAWINHQVSATRLVGGGKNKREVPVYKTFKEFFDYETEIKKITNEIDESYDKKAMD
                     LLLKANL"
     gene            10930..14184
                     /locus_tag="TVB59_001424"
     CDS             10930..14184
                     /locus_tag="TVB59_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HEL1010308.1"
                     /translation="MGESYSVEAVLTAVDKTFGKTLKSAVQSIEGLEKRSKGFSAVSQ
                     KAGSMFKSMLGANLAGQAITALGRTVSSGLISMIGEMNSSAKAWKTFDANLADIGFGK
                     QQILEAKTAMQDYATKTIYSASDMASTYAQLAAVGVKDTGKLVKAFGGLAASAENPKQ
                     AMKSISQQMTQAVGRPTVAWQDFRIMLEQAPAGMAKVAKAMGKNLNELVADIQAGRVK
                     TKDFLEAVKQAGNDKSFQKMATEFKTVDQAIDGMREGLSNKLQPAFEKVNQFGIRAIE
                     AIGKQLDKINFSKFAAGLGKFLEGVNIDSIISRISTSISSIVSKIKGFWDGFNQTGAI
                     SAFSGALQSVWGALKNTAKAMSGGSWKTFGSIIGEIVKHVSNFARVIGDVVGKMDPSR
                     LKSWIATLAAVGGGLKIFEKLTGQSVIGSFLDKIGSKFKIFGNKAKEGTEQAFNGVKR
                     SGGIISKIFNGLGNIVKSAGTAIATAAKGIATGFSIAFKGLGSAISMVPPATWLALGA
                     AILAVGAAFALAGTQADGISQIFKTVGDVVVQVLQQVTNSLATLIPIIVSAIGSILPI
                     VAGAISQVVAAVAGGLSQIITAVANGVSTIIGAFTGLLGGVSSVITSISGVIQSLAGV
                     ITSVFNGIATIISSVGSAIKDVLTGLGSAFKGFGNGVKSALEGVGTVIKSFGSAVRNV
                     LDGVAHIFDSMGNAALNAGRGVKEMAKGIKMLVDLSLADLVATLGAVATGLGNMAGSA
                     GQMTTLSSAMSEVANGMARLGTSATIAITGLTVFATTITTIQTAIATLPTILTAAASG
                     FREIGDSATAAVGRIQTFAAGTTVVASAFASMQSMIRSAMAAIVSSIITSFNQAASQI
                     QSILSRVLSQARTFGSQLEQQMRQSGQRSGQNLAQGLSSQQGAVINAVSSMVNAAVSR
                     ANAGASPMRQAGAYIGQGLAQGMYSALGAVTAAANALVAQAERAARAKAMIHSPSRLF
                     AKRVGQYIPQGVAMGIYKNADVVDDSVGELFDSINSFDFNIADRLTSIGARFQGVVKS
                     ESSQSLSQQQEFVHTAQPAYVNFSLGGNEYEAFVSDITNRQAKIEKIRLKRSSW"
     gene            14216..14995
                     /locus_tag="TVB59_001425"
     CDS             14216..14995
                     /locus_tag="TVB59_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HEL1010309.1"
                     /translation="MYEFNDTIRGTPKVTFNLKTTIGEKVLEEELNNDLGTFRTLTVS
                     GRDMVDLEHQTTSVLGRDGEYFHNATVEVRKLEIKAKITGKDNRSMRLQYEKLNRLIV
                     SHNQVFLSFSDEPDRNYLGIFKSKDIPEEVSNEQIIGLVFICYDPFKMSDIKTKKGNT
                     VQNDGLFNTKPIITLNLSSSTKEIRLLHVESQKYIRLTGTYTTDEIKIDMTTGKITQN
                     GRNILSDLDMVNSRYFDLLPGKNTLQCDNATITADFREVYL"
     gene            14992..17049
                     /locus_tag="TVB59_001426"
     CDS             14992..17049
                     /locus_tag="TVB59_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1010310.1"
                     /translation="MIYLFDKLEQLVATVGTDDLLSWHFKVKNNDWDQASFEVPVDYD
                     IEPFVYFGFFNYDPSQKEDVFKLFKVIDYNLEDSKYYKGLDKAESDLDTIAIIKDKRF
                     RQSSADACIDGALEGTGYQVGKVEGISEIRTLSYYYISPRAAMIKMIEAFNCEFNVRY
                     TFVNNKITSRYIDLKKRFGKPTGKQFEHGNNLLKVVYEESTDDIVTCLIGRGKGEEIQ
                     YDEPEAKEVEGHLPEAEKRQGYGRRIEFSDVVWSVEKGDSIDKPAGQNFVALDSAREE
                     YGLSQNGELKHRWGVFVNEEIEDKAELLKATWDQLQRLSIPIRIYKAEILDIGPETWK
                     GDSVAIIYDEVKIAFETRVDEIDIDKLNFNRSVVTLGDYSVVQNREARSRKEAVQNMI
                     NDSIENITGLGMNLQEFFQGIEEKIATGKKEMEDNWRKVNLEFDNFKKLIEQEGRNFR
                     ERLEAETKELDERNQKELDEFRETLKNLSLPEEAIKKITEAIKVDDIPSLKQSFDELK
                     NEVSKNSEKSRLNAEIIGTNGKTRYNKNLLVGEPNRTKTYDQDFVEIEANDGGFRRGE
                     TYTISFSQTCELLKKVAITLTQPHNKGLKLVLTPTKAKMEAQTFDLTKDIEVISVYPL
                     SYRAVLTGDWYKSKQMDFNAAEVQDLALEMSYRDVVDSNNASLILDWSSNPDVIFDGN
                     GGS"
     gene            17049..17756
                     /locus_tag="TVB59_001427"
     CDS             17049..17756
                     /locus_tag="TVB59_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HEL1010311.1"
                     /translation="MSETISAIVVHKSMTKNEWESSDIILPQGQLVYESDTGHSKFGD
                     GKNRYADLIYQGGPPGAQGPQGPAGETGPQGPPGPTGQRGETGPQGPPGPQGPPGADG
                     KMTFEQLTPEQKQQLKGAGIQSISLDYEGYLTIQLDNGQSFRSDISLKGPQGEPGING
                     MDGPRGATGPQGPAGDPASIPDDVVRRGELAAYLLKSEYKAKGAGSGLSYKVVTQSEY
                     DDLYDYSDNELILVTEG"
     gene            17758..18372
                     /locus_tag="TVB59_001428"
     CDS             17758..18372
                     /locus_tag="TVB59_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010312.1"
                     /translation="MAYKLYTKADVGDNMLLVVGHLPDNTKRLKIQRETLDVLSITHY
                     SSYDMVQLKSTVKRSHSKNTVVTLVAAAASKPKAKPKHVLNFAKANKVYLGSTRVIAV
                     YLGDRLLWSDKDSSGNKTVSVVGSLDIRQSQKMLYLYLIASDIADVKSKRIKSIAING
                     VNLSSAAQINFEDSDYYCLVTIERVANIKEIKNIAQKNKITLEF"
     gene            18383..>20223
                     /locus_tag="TVB59_001429"
     CDS             18383..>20223
                     /locus_tag="TVB59_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gp58-like family protein"
                     /protein_id="HEL1010313.1"
                     /translation="MSRDPTIVIDETNLVIGTDGRMHYTFTASQDNQKVRLKSNCLGT
                     AHFNQLMIERGDQATDYVAPVVVEGTGQATGVFKSLEEMLSGLKSIKLELTDTKNSNL
                     WSKIKLTTNGLLREYHHDHISTEIVETAAGIAKRIVDDTGQKLALINETIKGVKREYQ
                     DADRQLSASYQASIDGLKAQLANDKIGLQAEIKLSAQGLSQKYDDELRKLSAKITTTS
                     SGTTEAYENKLEGLRAEFTRSNQGMRTELESQISGLKAVQQSTAKQISQEIKDRAGAV
                     SRVQQDLDSYQRRLQDAEDNYSSLTQTVKGLQSTVSDPKGKIQSRFTQLQGQIEHRVT
                     RDGVMSIINESGDSIKLAIQKAGGIDAKMSAKEIISAINLNGYGVRISGERIALDGNT
                     TVNGAFGAKLGEFIKLKADQIIGGSIDAAKIRVINLNASSIVGLDANFIRAKIEHTIT
                     SLLEGKVIRARNGAMMIDLLNSKIDFNSNATINFNNKDNALVRKDGTHTAFVHFSNAT
                     PKNYTGSALYASIGITSSGDGINSASSGRFCGARFFRYARGYEHTALVDQAEIYGDDI
                     VFSDDFNIDRGFKMRPSLMPKMVDLNKMYQAILALGRCWLHANNTAWT"
BASE COUNT         6799 a         3554 c         4552 g         5318 t
ORIGIN      
        1 tttaataagc atatttatga taaattatat gactatgaca cttttacaga ggtccattac
       61 ggcggagcat cgtctggtaa atctcatgga gttattcaaa aagtagtatt aaaagcatgc
      121 caagactgga agcaccctag aaaggtgctt tttttacgca aagttggtgc aactgtttat
      181 gactcaatat tcgaagatgt gaaacagtgt cttgagttat ggggtctact agacaagtgt
      241 aaggttaata attcagcata taggattgag ctgccaaatg gggcgacatt tatttttaaa
      301 ggcctagaca accctgagaa aatcaagtca attaaaggcg tgtcagatgt cgttatggaa
      361 gaggctagcg agtttacgct tgatgattat actcagctaa ctcttcgtct gcgtgatcgt
      421 aaacatttaa agaaacaaat ttttttaatg tttaacccgg tatcaaaagt aaactgggtt
      481 tataaagcct tcttcgttaa gacacctaag aatacagttg tctatcaaac aacttataaa
      541 gacaaccgtt tcttagatga tgtcacgaga gaaaatatcg aggaactagc caataggaat
      601 gaagcttatt acaaaatata tgcccttggc cagtttgcga cattagataa gcttatcttc
      661 ccaaaatacg aaaagaaaat attaaataaa gacaaattat cacacttgcc ttcttttttt
      721 ggcttggact atggatttat taatgatcca tcggcatttt tgcatgtcaa aattgatgat
      781 aacaataaaa aactttacat cttagaggag tatgtgagaa aaaatctaac aaatgataag
      841 atagcaaatg ctataaagga cctcggatat gccaaagaag agattagggg agactcagca
      901 gaaaagaaat caaatcaaga gcttagaaat ttaggtatcc caaggataat cgatgttaag
      961 aaaggtccgg ggtctgtcat gcaagggatt cagtatctgc tgcaatatga ctggatagtt
     1021 gatgaaagat gtgtcaagac cattgaagag ttagaaaatt atacctggaa aaaagataaa
     1081 aaaacaaatg agtatattaa cgacccagtc gatagttata accactgcat tgacgcgatt
     1141 aggtatgcga catctaatca tttcttgaca ctggacaaaa aacaatccaa tagctttaat
     1201 attttccgca aagcaggttt cggactctag aaaggagaac aatgttatac acagaaacgt
     1261 ttaaagacag cacaggtaat gctaaattac ttgagtttag attccatcgt gagtctcgta
     1321 tgaggtatca gacaagcgat ttaagcggcc tttttgacga agggtataaa ctattgcttg
     1381 actatatcaa acaccacgaa agcaagcaaa aaccacgcat acaggagctt ttagactatg
     1441 ctgagggtaa taatcataca gtctgcgaat caggccgcag acgagaggct gatatggcag
     1501 acagtcgtgc tatacacaac tacggtaagt atatctcgac ctttaagcag ggctatttag
     1561 ttggaaatcc tatccgcgtg gaatatgagg acaatgatga tgctaaaaaa caattgttca
     1621 aggagctggc ggataaaaat aacttccacc aacttaaccg tagacttgtc aaggatttat
     1681 ccaaggtagg ccgcgcctat gaacttatct atcgcagcat ggacgataag acagaggttg
     1741 tgcgattaga tccacgagaa acctttatta tctatcaagc tgatgttggg caagctagcc
     1801 ttgtgggtgt gaggtactat aacaagagtc agctggatag aacaaagaaa acagttgagg
     1861 tctacacaga taacgagatc atttactttg attatgatgg gcaactgaca gaggttgata
     1921 ggcggccaca catttttaaa tctgtaccta tcacagagta tctcaatacg gacgatggcc
     1981 ttggtgatta tgagacggag ttgtctttaa ttgacttgta tgatgcagct caatcagaca
     2041 cagcaaacta tatgcaagat ttgtcagatg caatcttggc tattattggt cgagtatcgt
     2101 tcccgagtta tgtagacacc aaggaaaaag ccattgaata tctgcgtgct atgcgcaaag
     2161 ctaggttgct aaatttagag ccaccagtgg ataccgaagg tagagaaggt tctgtagatg
     2221 ctaagtatct ctataagcaa tatgatgtca acggcacaga agcttataaa gatagggttg
     2281 tgcaagatat ccacagattt accaacacac cagatatgtc agatagcaaa tttgcaggca
     2341 cgcaatctgg agaggcactc aagtggaaag tctttgggct tgaccaagag cgtgtagact
     2401 tgcaagcact gtttgagcaa tctctaaaac gtagatataa gcttatcgca agagttagtg
     2461 agctgttaaa agaaattgac ggatttgaca ttagcaaact taaaattact tttaccccta
     2521 acttaccaaa atcgctacat gaaaaaattg aagcttttaa agcacttgga ggggagttgt
     2581 cgcaaaaaac aacaatgtct attacagata ttgtggaaaa tcctgataaa gagattgctt
     2641 ccatcaacga tgaggctaaa aatcgtagtt tattggcgca aaagatggag tcagaaggta
     2701 gaatgacgga tagggagtta gctcgtgact acaatcatga ataagagtaa atattggcgt
     2761 gatcgtgtta aaaaagaaat ggacgcaaaa gaggcagatg atatctccct tgaacagtcc
     2821 atgaaacaat tacacaatta tcattttaga aatatcgaaa aagaaattga gtcattttat
     2881 caacgttacg ctgataaaga gaaaatagac atcgcagaag cccgtaagag agtttctgag
     2941 cttgacattt ctgcttacca gaagaaagct aaggaacttg ttgtaaaggc tgagaagcta
     3001 cgaaaagagg gtaagacagt aacgagagat gactttaccc accaagaaaa tgcagacatg
     3061 gccatctaca atttagcgat gaaaactaac gctttagaat tgttgcgctt gaatatcgac
     3121 ttggagatgc aggagctcgc aaatggcgaa cataagctaa ccaagacatt tcttgacgaa
     3181 ggataccgca aagaggttga gttccaagcg ggattgttag gactgtcggt tgctagccaa
     3241 gcaagcgtga aagggttggc tgacgcagtt attaacgcta atttcaaagg cgcaaaatgg
     3301 tcggatagca tttgggacag acaagataaa ttacgcagca ttatatccca gagcgtacag
     3361 agtgctatct taaaaggtaa aaatggttta actattgcaa gggatattag acgagagttt
     3421 gatgtgtcag tgtcttatgc aaagcgaata gcaatcactg agcatgcaag ggtgcagatg
     3481 gaagttagta gattatccat ggcggagaat ggctttgcta tgtttgacat tatcccagag
     3541 cctaaagcat gtgatgtttg taaagacatt gctaaacaag gtccatatca catggataag
     3601 tggcgaacag gggaaaacac gccgcccatc catccttatt gcaggtgtgc agttgttgga
     3661 gtggaagaag aaaatagtag taatcatgaa tcacttgata agcttattaa aacagagtat
     3721 aatcaaagta tgaaagagtc atcgacttat gctcgtaacg ttttgtcggc agtgtcattg
     3781 atagagcctc gaattacatc gcaaattaag catattgtca agcaatccaa cggtaattta
     3841 caaggacttg attttagatt aaaaagtcta gattctttgg ccagaaagat ctctactgat
     3901 agcttgttgg acgatatttc accggaagaa gccgcaaaca acataaatga tgcattacgc
     3961 tatacagctg tatttaaacc agataatttt tttgatgatt atcatagcat gaaaaatgca
     4021 ttggtcagag atggttttaa aatcgaaaag gtgaaaaata cttggctaga tgatggtcca
     4081 tataacggtg ttaatactgt tgtatcaaaa gacaatgtca agtttgaaat tcaatatcat
     4141 acccaagaaa gctttgattt aaaaaacggg aaactgcatg aattatatga ggagagaaga
     4201 cttcctaata taacacgaaa acggaaggct gaactagaca aaatgatgtt tgagcttagt
     4261 aaatctttaa ctaaacctaa ccaaatagaa agggtgaatt gatatgatta caaaatattt
     4321 ttttataaaa accgaacacc ccaaaattgt tagatattct aatgggttaa cagaagttta
     4381 taacagcgca aaaggctggg aagaacaaga agcttggtac gatcgtctat tctttagcga
     4441 tttcagtgat tttgaagagg ttacagaaaa agaagctaaa atgtttattg cgggattgac
     4501 agcggcatga gtattgtgga gctagctttc agagtggcta aaaaagccca ccttggacag
     4561 gttgataagg ccggtgtcga ctatattaag caccctataa ctgttgcaag ttttgtaaaa
     4621 actgatgaag aaaaggcaac ggcttatctt catgatgtta tcgaagatac aagtttgact
     4681 ttacttgact tggaagagta tgattttcct cgaagtgtta tagaggcagt tgatatactg
     4741 acaaagaaaa aaggacagga ttatcaatcc tatctaaacc ttgttaaaac aaataaactt
     4801 gcaagaactg taaaattagc tgatttaaaa cacaattctg atttatctcg tctctctgaa
     4861 gtaactaaca aagatttaaa acgctataaa aaatatcaag aagctatcaa atatttaaac
     4921 aattaaacaa caacagacgg gcaaccgtct ttttttgtac cccaaaaaca ggaggaaatg
     4981 atgttgaaaa tagtgaaatt tttgaaatat gtttggattt ataagtgtaa acctgtcagt
     5041 ccaagtcttt atgcatcgag tcggattgag tacttcaaac ctcttggtta ttactgggaa
     5101 aaagcaacga taggagaaag caatgaataa acgaatcaaa aagaaacgta aactagaaac
     5161 agtagtagtg atgctggttg cggaaaatgc cttgcaggct gaagcgctca taaatcaaaa
     5221 caaagaaatc atggagctaa aatcaatcgt tgagcgaaac gctctggcaa caaacgaaga
     5281 gttagcgact gttaaagaca ccgttttaga caaccaatca gttatcaagg caattggtga
     5341 cacggttgac tacatcaagc aaaattacaa acgtaagtgg gggaagaaat gaagtatctc
     5401 aagaaaaagt aatagtaagg agttattttg aaagtcaaag agatagcaca ggtgtttaat
     5461 gaatattcgg atttttttgt ggtacaaaac ggtaaatatc tacctggtga cagaactagt
     5521 ttttttctag attgcgaatt ggaaatcaaa gaaatatcta tcggaattcc tgattgctta
     5581 attattgaag tataaaaaat tcaaagtcgt agcaatacgg ctttttattg tgccctgagc
     5641 atggcctaaa aaggctcaaa ttaatcacta gcgtggcttg tggataaata cacctaatag
     5701 agactagaaa acatgaggcg cccgttttcg tggctctgca gtgtgtttaa aagcaagact
     5761 agcgtgggag gaaaaaatga ataaaaaact attagaaaaa ctttttaaat gtgctccaga
     5821 tactggcaca ggttcaggag gagcttctga tgcagatagc caacaatccg aaacagatgg
     5881 agaaccatct agtgaagaca gctttaaagc tccacagtcg caatcagagt tagatagcta
     5941 tacgaataaa gcaatccaaa aggcattgga aaatcaacgc aaagatgaag ctaaacgaat
     6001 agaagaagct gtaaaagctg ctttagataa agaaaaagac tactccaagc tatctgaaga
     6061 agaacgtcag cagcgtgaat ttgaagatag taagaaagcc tttgaagctg aaaaagccaa
     6121 gtttgaacac gataaacttg tagtccaagt cgaaaaggat cttatcgcaa agggattgcc
     6181 ttctgagttt gctgaattgc ttgctacaaa agatgcagaa aatgcgctag agcaagtcaa
     6241 aacattcgaa gcagcattta aaaaagcagt agctgatgaa gttaaaaaga ccgtacgaca
     6301 acttactcca tcaactgggg caggtgcaat atcaacacaa acaaactatg gggcgaactt
     6361 ggcgagtaag atcgcacaac aaagcaccac attattttag gaggaaaaaa atgaataaac
     6421 gtaaagtaac aacatcaaaa gagattctcc acaatctcga atacgaagct attacagtca
     6481 ctttagattc aagcacagtt ggcaaaaaag ttattccagc cggtacagtt ttggccggtg
     6541 tatcggattc tgtttttaaa gatcgcaaac aaaaagtaaa aactgtggca aatcacgagg
     6601 tcagcggaga gagcaatatt tgtggaattt tgttaaccga tgttgatttg acagatggtg
     6661 ataaagcagg tgcttgtgtt tatcgcggta ctgtcaacgc agataaactt gctgattcat
     6721 caattgcaga aaattttacg gaattggcga caaaactacc acatgttgtc tttattaagg
     6781 gaggtaagta agcatggcat tgatccacga aattatcaca tcggaaaaca tcaaaggttt
     6841 ttataatgct aaaaatgaga acattgataa aacgttaggg gaaaaagcat tcccaccaaa
     6901 acagcaatta gggcttaagc tatcctttat caagggtgcg gcaggaaaac ctgtgacact
     6961 taaagcggcc gcttttgata ctaaagtacc tctacgtgac cgcatggcag ttgagctgct
     7021 tgacgaagaa atgccttact ttaaagaggc tatgcttgtt aaagaggcag accgtcaaga
     7081 gcttaacatt atatctcaaa caaaaaatag tgatcttatt gacacagttt tagcggcaat
     7141 ttataacgat aaggtaacgc ttatcgcagg cgctaaagca cgtttagaag caatgcgtat
     7201 ggaagtgctg tctaaaggta aaatccacgt cgcatcaaac ggtgtcatga aagactttga
     7261 ttatggacta gactcttcgc aaacaactaa gccaagtgtt aaatggtctg aggcagagac
     7321 cgcgacacca cttaaagaca ttgaaggtgc aattgaaaaa atggcagaac gtggctttgt
     7381 gccagaagca attatcatga actctaagac atttagtttg attaaaaacg ctaaatcaac
     7441 tcttaaaatc atcaaaccaa tggcaccaga tggggcagct gttaccaaag gtgatttgac
     7501 gacttatatt gctgatgaac taggactcaa aattttgttt aaagatggta tgttcattgg
     7561 tgacgatggc aaatctcgta agtatttccc agatggcttt gcaactttgg tacctaacgg
     7621 caaccttggc tacactgtgt ttggcactac tccagagcaa tcagatctca tgggtgggca
     7681 cgcaacagat gcagatgtgt cgttggttga gactggtatt gcaatcacaa ctactaagac
     7741 aactgatcca gtaaatgttc aaaccaaggt atctatgatt gctttgccgt cattcgaacg
     7801 attggaagaa gtgcaaatta tcgactccat tgaccaagta taaggagggg gttatggctg
     7861 aagttattaa aacttttagg gataaagaaa ccactaacac ttactacgta ggagacgatt
     7921 acaacggaga ccgcattgat gagttgacag ctaaaggata cctatctggt gataaggttt
     7981 ctgctgccgc tatagagatt gaccttgaca aattaaaggt tgacgaaatt agagcaaaac
     8041 ttgatgagtt aggcgtcgct catgacccta aactaaaaaa gccagaatta ttagaacttt
     8101 tgaaacagtc agctagctag gaggtgttta tgcaaaagat aaacacagat agcattatag
     8161 ctaacgtaaa actcgattta ggtattgatg acaccttgca agacagtttg ctcaatatgt
     8221 tgctaaaacg tgttacagac cattttaaag cggaatacgg cgttgatgat atagacaacg
     8281 ccttttcgtt tgttttggaa gactgtctaa ttgctaggtt taatcgcaga gggtcagaga
     8341 gggctaagtc ggaagaggta gagggtcata aaacaaccta ctatgacttt ttaaatgagt
     8401 ttgagcctta cgacaaaatg attaagtcca accttaattt gattaaggat aattctcgta
     8461 aagggggatt gtacttttta tgagatatgc agataggatt acgtttgtta aggcgacaga
     8521 tgaacaatat gaccctgatt taggtgagta cacatatacc gaagtcatga tcaagacatt
     8581 gccttgtttt gtcatggact taggtatggc taaatctgtg cagattttcg gagactatca
     8641 aaaaacacga aaagttgttt atttgcgcca accttatacc gatttgttag atcactgtct
     8701 ctacaaaggc aaaaagtaca aggtacaggt ggataagcaa tttaatactg ttttttatct
     8761 ggagggagat gattctattt gtagctgata tatctttaaa agtagttgga acgacagggc
     8821 taaagaataa acttgaactt attgccaaaa aagaggctgt caagaagatt gttagagata
     8881 atggaaaaca actacacagg aaaatggtcc aaaaggcagt atttaccaaa ggtcattcca
     8941 ctggtgctac cagaatatcc atcacaatgc agattggtga tgatggtttt agtgttacag
     9001 taaaacctgg cacgcattat gcaggttatt tagaaaaagg cactcgcttt atgagtaagc
     9061 aaccttttgt gttgccagct ctaaaagagc aaaaagtaaa attcagaaaa gatttggagg
     9121 cgcttgtcaa atgattaaaa ctagagatca atctattttt gacgagatgt ttaagcgtat
     9181 tcagtcttta ggttttaaag tttatgatta caaaccgatg actgaggttc cttatccgtt
     9241 tgtggaaatg gaatctactg atgcagaata tattccaaat aaagatgaca ttaaaggctc
     9301 tgttgacctc gtactgtctg tttggggatt gcaaaaaaaa cgaaagcagg tgtctgatat
     9361 ggcatctgct attttttcac aagctatgtc agtggctagt tctgacagct tttactggtc
     9421 gttaaatatt cgtcaatcat ctatccaagt gttagatgac acaacaacag tgacacctct
     9481 caagagagcg attgtcacat taagatttaa tttaagatag gaggtcgcaa tgccaggacc
     9541 aagtagatta ggatccaaag atgaagacca ctccacacaa gaaaggaagg aaaaaatggc
     9601 agcgcaagat caagtacaat tagaagcaaa acaagggatt catgcaatcc tattattccg
     9661 tttgttaaaa gaagcatcat cagaaaaagc agctaaactc gcttttcaaa cggaacacga
     9721 agttggtaaa agtcgtgatg tcgacggtca aaagactaaa gatggtatta tccagtctgt
     9781 cggagcttta gaatacgact ttaaagcaac atctatttta gccaaaggtg acaagttagc
     9841 agcaaaacta gaagaagcca tggaaaaagg tgagcttgtt gaaatttggg atattgattc
     9901 cgaaaaagca agtgaagaag cttgatagca aaggtaaata tccagctacc tattaccaag
     9961 gttacatttc aagtttcggc gctaagaaaa atgcagaaga aaatattgaa attgaaatgg
    10021 aatttgccat taatggcgtt ggtcaaaaag gatttgcaac attgaccgaa gaacaaaaag
    10081 cagctgtaca gtacaaattt aaagatacaa cagcaggtta atcaacaagg ccagttaatt
    10141 actggtcttt tatttttaaa tttttaaagg gggaaaagaa taatgcaatt ggaaattaaa
    10201 ggtaaaactc ataacatcaa atttggcaca cgatttgttg ctgaaatgga taagaatcac
    10261 attgcagaac gtgaagggat gaagtttggc gctggtttgc aatcaactgt tccgtttttg
    10321 tttgagcgta acgttgtgac acttgctgag attatctata cagggacaat cacagagtca
    10381 ccacgaccaa gcttaaatga tatttacgac tacatcgatg aggctgaaga tattgagaag
    10441 cttttcgatg atgttttaga tgagttgcgc caatctaacg cgtcaaagtt gtttatcacc
    10501 aaactggaca aaaacatagc ggagatggca accgaagctt aaagagttca accaaaaatt
    10561 attcttcaca agaaagcttt gagatgattg tccttaattg tgttagatat cttggcatga
    10621 ctgacattaa tgagattggt cggttgactt tgtatgaata tgatttattg atgataggta
    10681 aagcgctagc ctctgtagac gaggcatata aagctcacaa gcaagcttgg ataaatcacc
    10741 aggtctcagc tacgaggctg gtcggtggtg gtaaaaacaa aagagaagtt cctgtttata
    10801 aaacattcaa ggaatttttt gattatgaaa cagaaatcaa gaagataacc aatgaaattg
    10861 atgaaagcta tgacaagaaa gcaatggatt tacttttaaa agccaacctt taaatagaaa
    10921 ggaagttaaa tgggagaatc ttattcagtt gaagcggtgt tgacagcggt tgataaaacc
    10981 tttggtaaga ctttaaaatc agcagttcaa tcaattgaag gactagaaaa gcgttcaaaa
    11041 ggcttctcgg cggtgtctca aaaggctggg tctatgttta aaagcatgct tggagctaac
    11101 ttagcaggtc aagctattac agcgctagga cgtacagttt catctggact tatttcgatg
    11161 atcggcgaaa tgaatagctc agcaaaagcg tggaaaactt tcgatgccaa tttagcagat
    11221 atcggatttg gcaaacagca aattcttgaa gctaaaacag ctatgcaaga ttacgctact
    11281 aaaacaatct actcagcatc agatatggcc agcacatatg cacagttagc tgctgttggg
    11341 gtaaaggata ctgggaaact cgtaaaagct tttggtggtt tggctgcatc tgctgaaaat
    11401 ccaaaacaag ctatgaagtc aatcagtcag cagatgacac aagctgtggg aagacctaca
    11461 gtagcgtggc aagatttcag aataatgctc gagcaagctc cagctggtat ggctaaagtg
    11521 gccaaagcta tgggcaaaaa ccttaatgaa cttgtagccg acattcaggc tggtagagta
    11581 aaaactaaag acttcctaga agcagtaaaa caagctggta acgacaaaag cttccagaag
    11641 atggcgactg aattcaaaac tgtggaccaa gccattgatg gcatgcgtga aggtttatcc
    11701 aataaattgc aaccagcttt tgaaaaagtg aaccaatttg gaattagagc gattgaagca
    11761 atcgggaaac aactcgataa aatcaatttt tccaaatttg ctgcaggcct tggtaaattt
    11821 ctcgagggcg tgaacattga tagtattatt tcaagaatat caacatcaat ttcatctatc
    11881 gtttctaaaa taaaaggatt ctgggacgga tttaatcaaa ctggagcaat cagcgctttt
    11941 tccggtgctt tacaaagtgt ttggggagcg ttaaaaaata ctgctaaagc catgagtgga
    12001 ggaagctgga agaccttcgg gtcaatcatt ggcgaaattg ttaaacatgt ttctaatttc
    12061 gcaagagtga ttggagatgt cgttggcaag atggatccga gtagactaaa aagctggata
    12121 gctactcttg cagctgttgg tggtggattg aaaatctttg agaaattaac aggtcaaagt
    12181 gttattggat cttttttaga caaaatcggc tcaaaattca aaatatttgg aaataaagcc
    12241 aaagaaggga cagaacaagc ctttaacgga gtcaaaagaa gtggtggcat tatcagtaaa
    12301 atctttaacg gtttgggtaa tatcgttaag tctgccggta cagcgatagc gactgctgca
    12361 aaaggtatcg caactggttt ttctatcgcg tttaaggggc ttgggtctgc catttctatg
    12421 gtaccgccag ctacatggct agctttagga gcagctattt tagcggtagg agcggctttt
    12481 gccttggcag gaactcaagc tgatggcatt agtcaaattt ttaaaactgt tggcgatgtc
    12541 gttgtacaag ttttacaaca ggtcactaac agtctagcta ctctaattcc tattattgta
    12601 agcgctattg gctccatatt accaattgta gcaggggcta tttctcaagt cgtcgcagca
    12661 gttgctggcg gattatctca gattattaca gctgttgcta atggtgtatc aactattatt
    12721 ggggctttca caggtctact tggtggtgtt tctagcgtca ttacctcaat tagtggtgtt
    12781 atccaatcgc tggcaggtgt aattacctca gtatttaatg gcatagcaac cattatttcg
    12841 tctgtagggt ctgcaattaa agatgtatta acgggtctcg gcagtgcttt taaaggattc
    12901 ggcaacggtg taaaatcagc cttagaaggc gttgggacag taatcaaatc atttggtagt
    12961 gcagtcagaa atgtccttga tggtgttgcg catattttcg attctatggg taatgcagct
    13021 cttaatgctg gtcgtggcgt caaagaaatg gctaaaggca tcaagatgct tgtagattta
    13081 tcgcttgctg atttagtcgc aacgcttgga gcagtcgcga caggtcttgg gaatatggct
    13141 ggctctgccg gtcagatgac tacgttaagt tctgccatga gcgaagtagc caatggtatg
    13201 gcgcgtctag gaacaagcgc tacgatagca attactggat taacagtttt tgctactact
    13261 ataacaacta ttcagaccgc aattgcaact ctaccaacaa tcctaactgc agccgctagt
    13321 ggttttaggg agatcgggga ttcggcaact gcagcagttg gtcgaatcca gacttttgca
    13381 gctggtacaa ctgttgttgc atcagcgttt gctagtatgc aatctatgat tcgatctgcc
    13441 atggctgcaa tagtaagcag cattataaca tcatttaacc aagctgcctc tcaaatacaa
    13501 tcaattttat ctcgggtgct atctcaagct aggacatttg gatctcaact agagcaacaa
    13561 atgaggcaat cgggacagcg ttcaggacaa aatcttgctc aggggttgtc ttctcaacaa
    13621 ggtgctgtta ttaatgctgt ttctagcatg gttaatgccg cggtatcaag agcaaatgca
    13681 ggtgctagtc ctatgcgtca agctggagcg tacatcggac aagggcttgc gcaaggtatg
    13741 tattcagcgc taggagctgt aacagcagca gcaaacgctc ttgtagcaca agctgagagg
    13801 gcagcaagag ctaaggcgat gattcactcg ccatctaggt tatttgcaaa acgagttggt
    13861 caatatatcc ctcaaggggt agccatgggg atatataaaa acgctgatgt cgttgatgat
    13921 tctgtaggtg agctatttga tagtatcaat agctttgatt ttaatattgc ggatagattg
    13981 acaagtattg gcgctagatt ccaaggtgtt gtcaaatcag aaagttcgca atcgttgtcg
    14041 cagcaacaag agtttgtaca tacagctcaa ccagcgtatg taaactttag tttaggcgga
    14101 aacgaatacg aagcatttgt aagtgacatc actaatcgac aagcaaaaat tgaaaaaatc
    14161 agactaaaga gaagcagctg gtagttgttt ctcttagttt tatgaaagga gtaaaatgta
    14221 cgaatttaac gatactatca gagggactcc gaaagttact ttcaatttaa aaacaacaat
    14281 tggcgaaaag gtattagaag aagagctcaa taatgattta ggtaccttta ggacattgac
    14341 cgtttctggt cgtgatatgg tggacttaga acaccagaca acaagtgttt tagggcgaga
    14401 tggcgagtat ttccacaatg ccacagttga agtcagaaaa ctagaaataa aagctaaaat
    14461 tactggaaaa gataaccggt caatgcgttt gcaatatgaa aaattaaaca gattaattgt
    14521 tagtcataat caagtttttt tatcattttc agacgagccg gacagaaatt atctaggcat
    14581 ctttaaatct aaagatatac cagaagaagt ttctaacgaa caaatcattg gcttggtttt
    14641 catctgttat gatccattta aaatgtcaga tataaaaacc aaaaaaggta atactgttca
    14701 aaatgatggc ctatttaata caaaacctat cataactctc aacctctcat catcaacaaa
    14761 agaaattagg ctgctacacg tcgaaagtca aaagtatatc agattaactg gtacttatac
    14821 tactgacgaa atcaagattg atatgacaac aggtaagatt acccagaacg gccgtaatat
    14881 tcttagtgat ttagacatgg ttaacagtcg ctattttgat ctattacctg gtaaaaacac
    14941 tttgcagtgt gataatgcaa cgattacagc tgatttcagg gaggtttatc tatgatttat
    15001 ctctttgata agctggagca attagttgct actgttggta ctgatgactt gctctcatgg
    15061 cattttaagg tcaaaaataa tgattgggat caagctagtt ttgaggtacc tgttgattat
    15121 gacattgagc cttttgttta ctttggtttt tttaactatg atccaagcca aaaagaggac
    15181 gtttttaaac tctttaaagt cattgattac aacctagaag atagcaagta ttataaaggc
    15241 ttagataagg ctgagagtga ccttgatact attgctatta tcaaagacaa gcgctttaga
    15301 caatcgtccg cagatgcttg tattgatgga gctttagagg gcactggtta tcaagttggt
    15361 aaagttgagg gcatttccga gatcaggacc cttagctatt attacatcag cccacgagct
    15421 gccatgatca agatgataga agcttttaac tgcgaattta atgtcagata cacctttgtt
    15481 aataacaaaa ttactagtcg ctatatcgac cttaaaaagc gatttggcaa gccaacagga
    15541 aagcagtttg agcatgggaa taacttatta aaagtcgtct atgaggaatc aacagatgac
    15601 atcgtgactt gtctgattgg ccgaggcaag ggcgaggaaa tccaatatga tgaaccagag
    15661 gcaaaggaag ttgaaggaca cttaccagag gcagaaaagc gtcaaggtta tggccgaaga
    15721 attgaattta gcgatgttgt ctggtcagtc gaaaaaggcg actcgataga caaaccagct
    15781 ggtcaaaact ttgtggcgct agatagtgcc agagaagaat acggattgtc tcaaaatggc
    15841 gagctaaaac accgatgggg ggtctttgtc aacgaggaaa ttgaggacaa ggcggaactc
    15901 ttaaaagcca catgggatca attgcagcgc ttatcaatac ccatcagaat ttacaaggcg
    15961 gaaatcttag atattggccc cgaaacgtgg aaaggtgact cagtagccat tatctacgat
    16021 gaggtaaaaa tagcttttga aactcgtgtt gatgagattg atattgataa gctaaacttt
    16081 aacaggtcgg tagtaactct cggtgattat agcgttgtcc aaaaccgcga agcaaggtca
    16141 cgcaaggaag ctgtccaaaa catgatcaat gatagcatag aaaacatcac cggccttggc
    16201 atgaacttac aagaattttt tcaaggtatt gaggaaaaaa ttgccactgg caaaaaagag
    16261 atggaagaca attggcgtaa ggttaacctt gaatttgata actttaaaaa attaatcgaa
    16321 caagagggac gtaactttag agagcgttta gaagctgaaa caaaggaact agatgaacgc
    16381 aaccaaaaag aactcgatga atttcgcgaa accctcaaaa atctgtcgct gcccgaggaa
    16441 gccattaaaa aaataaccga ggccatcaaa gttgatgata tcccatcgct aaaacaaagt
    16501 tttgacgagc tcaaaaacga agtcagcaag aacagcgaaa aatctcgctt aaatgctgaa
    16561 atcatcggca cgaacggtaa gacccgctat aacaaaaatc tcttggttgg tgaacctaat
    16621 cgcaccaaga cctatgatca ggattttgtg gagatagaag caaatgacgg tggttttaga
    16681 cgcggtgaga catacacgat tagctttagt cagacatgtg agttgctaaa aaaagtggct
    16741 atcacgctga cgcagccgca taacaaaggt ctcaagctgg tgctgacacc aaccaaggct
    16801 aagatggagg cgcagacttt tgacctaacc aaggacatag aggttatcag cgtctatcct
    16861 ttgagctaca gagctgtttt aacaggtgac tggtataaat ctaagcagat ggattttaat
    16921 gcggcagaag tgcaggattt agctctggag atgtcttata gagacgttgt cgatagcaat
    16981 aatgctagtt tgattttgga ttggtcctca aatccagatg ttatttttga tggaaatgga
    17041 ggtagttaat gtcagagact atatcagcta tagttgtgca taaaagcatg acaaaaaacg
    17101 agtgggagtc tagtgacatc attttgccac aaggccagct tgtctatgag tctgacacag
    17161 gccatagtaa atttggcgac ggtaaaaata gatatgcaga tttgatctat caaggtggac
    17221 cacctggggc acaaggtccc caagggccag ctggcgaaac cggtccacaa ggcccaccag
    17281 gccctactgg tcaacgtggg gaaacaggcc cacagggtcc acctgggcca caagggccgc
    17341 caggagcgga cggtaaaatg acgtttgagc agctcacacc agagcaaaaa cagcagctta
    17401 aaggtgctgg catacaaagc atatcattgg attatgaggg ctatttgaca atacagctag
    17461 ataatggcca atcgtttaga tcagatatta gcttaaaagg tcctcaagga gagccgggga
    17521 tcaatggtat ggacggtcca agaggcgcaa cgggtcccca aggaccagct ggtgatccgg
    17581 cgagcatacc tgacgatgtt gtcagacgtg gtgagttagc tgcatatttg cttaaatcag
    17641 agtataaagc caaaggcgca ggctctgggc taagctacaa agttgtcact caatcagagt
    17701 atgatgatct gtatgattac agcgacaatg agttgatact cgtgacggag ggttgacatg
    17761 gcatataagc tttacactaa agctgatgtt ggtgacaaca tgttgcttgt tgttggccat
    17821 ttgcctgaca atacaaagcg attaaaaatc cagcgtgaga cgttagatgt attgagtatt
    17881 acccactata gctcttatga tatggtacaa ctcaagtcga cagtcaaaag atcccacagc
    17941 aaaaatacag ttgttactct tgtagctgca gctgctagca agcccaaagc taagccaaag
    18001 cacgttttaa actttgctaa ggctaataag gtctatctag gcagcactcg tgtaatagcg
    18061 gtttatctgg gtgatcgact gctctggtcc gacaaagaca gcagcgggaa caaaactgtc
    18121 tctgttgtgg ggagtcttga tatcagacaa tcacaaaaaa tgctgtattt gtacttaata
    18181 gcgtcagaca ttgcagatgt caaaagcaag cgcattaaat cgatagcgat aaatggcgtt
    18241 aacctgtcaa gcgctgcaca aatcaatttt gaggatagcg actattattg tctagtgaca
    18301 atcgagcgag ttgctaacat caaagagatc aaaaatatag cgcaaaaaaa caaaatcacg
    18361 ctagagtttt aggaggtaac aattgagcag agacccaaca attgtaatag acgagacaaa
    18421 cctcgttatt ggcacagatg gccgcatgca ttacacgttt actgctagtc aagacaacca
    18481 aaaggtcagg ctaaaaagca actgtttagg cacagcgcat tttaaccagc tgatgattga
    18541 gcgaggagac caagcgacgg actacgttgc gcccgttgtt gttgagggta caggacaggc
    18601 aacaggcgtc tttaaaagtc tcgaggagat gcttagtggc ctaaagtcaa ttaaactgga
    18661 gctaacagat accaaaaact caaatctgtg gtcaaaaatc aaattgacga caaatgggct
    18721 tttgcgtgag tatcatcatg atcatatctc gaccgagatt gtcgagacag cagctggtat
    18781 tgccaaacgg attgtcgatg atactggcca aaagctggca ctaatcaatg agactatcaa
    18841 aggtgttaag cgtgagtatc aagacgcaga tagacagcta tccgcgagct atcaagcaag
    18901 tatcgatggc ctcaaagccc agctggccaa cgacaaaatt ggcctacaag ctgagattaa
    18961 gctgtccgcc caaggcttgt cgcaaaaata cgacgatgag ctgcgcaagc tatctgccaa
    19021 gattacaacg acatctagtg gtactacgga agcctacgaa aacaaactcg agggcttacg
    19081 ggctgagttt actcgtagca accaaggcat gcggacagag cttgagtcgc aaatcagcgg
    19141 cctaaaagca gtacagcaat caactgcaaa acaaatctca caagagatca aggatagggc
    19201 aggggctgtt agtcgtgtgc aacaggatct agatagttac caaagacgct tgcaagacgc
    19261 agaggataat tacagtagct taacccagac cgttaaaggc ctgcagtcaa ctgttagcga
    19321 tcccaaaggc aaaatccagt cacgatttac acagctgcaa ggtcaaattg agcatcgtgt
    19381 gactagagat ggggttatga gtatcatcaa cgagtcaggc gatagcatta agctagcgat
    19441 ccaaaaggct ggtgggattg atgctaagat gagcgctaaa gagattatct cagcgattaa
    19501 tcttaatggt tatggcgtca gaatctccgg tgagcgtatt gcgctggacg gtaatacgac
    19561 cgttaacggg gcttttggag ctaaacttgg tgagtttatc aagctcaaag ccgatcaaat
    19621 tattggtggt tcgattgacg ctgctaagat tagagtgatc aatcttaacg ctagcagcat
    19681 tgtcggctta gatgctaact ttatcagggc taaaatcgaa catacgatta caagtttgct
    19741 tgagggtaaa gttatcagag ctcgcaacgg agcgatgatg attgacttgt taaactctaa
    19801 aattgacttt aacagcaacg ctaccattaa ctttaataac aaggacaatg cgcttgtacg
    19861 taaagacggt acccacacag cctttgtgca ttttagcaat gccacgccaa aaaattatac
    19921 aggtagtgcg ctttacgcct cgatcgggat aacctcgtca ggtgacggga ttaacagcgc
    19981 gtcgagcggt cgtttttgcg gtgctaggtt ttttaggtac gcacgaggtt acgagcacac
    20041 agcgcttgtc gatcaggccg aaatttacgg tgatgatatt gtctttagcg acgattttaa
    20101 catcgatcgt ggctttaaga tgcggcctag cctaatgcca aaaatggtcg atctcaataa
    20161 gatgtatcag gccattttag ccctcggccg ctgctggtta catgctaata acacagcatg
    20221 gac
//
LOCUS       DARYNN010000038        19804 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.038, whole genome shotgun sequence.
ACCESSION   DARYNN010000038 DARYNN010000000
VERSION     DARYNN010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19804)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19804)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19804
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.038"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(85..1350)
                     /locus_tag="TVB59_001430"
     CDS             complement(85..1350)
                     /locus_tag="TVB59_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HEL1010314.1"
                     /translation="MAEFHFDIDQIANNAITKTDKTTDIITKLPTNTTGQISFYEKLS
                     PEQQQAITAKAPALVDTFMEDQNALLDFGQAAVEGVNATVNHILAEQKKLQIPQVDEL
                     LKNTNRELNGFIAKYKEATAAELEKKPTLLQKLFKQSKNTLQEFYFDSQTIEQKMDGM
                     AAAVVKQEDTLARNIVAAELLIEDNTKSIENLVGVIAFLEASQKETSSRALTLQQELA
                     VLDTTTPEYQVQSDLLARTTEVLNTLEQQHTEYLSRLYVAWATTPQMRNLVKVSSDMR
                     QKLGMLRRNTIPTMKLSIAQLGIMQQSVKSGMTADAIVNANNAALQMLAETSKEAIPN
                     LERTAQSPTISLTSVTALAESLVAQNNGIIAAIDQGRKERAQLEAAIIKSAETINDSV
                     KLRDQSIIQALLNEGKEKQETIEQTERQP"
     gene            complement(1364..2221)
                     /locus_tag="TVB59_001431"
     CDS             complement(1364..2221)
                     /locus_tag="TVB59_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010315.1"
                     /translation="MSRKYYQVSRRRKGFSWFGWLIGFAILVGVVENIDKAVLIFAAL
                     GVGYAAYRYSNRQARLKTATLEKRLEDLKATIQLADRKVKLLDHYLAKEDFTQYAILA
                     KQLLPQLSEIKKESGHLKEHMDISIYRRVTKKANDVESDVQLQLEKIQIAANLKAESL
                     KEQAADPIYKAPELRHYYDNIQADHHSILEKIKGADNHEELLALHEANMRRFQDILQG
                     YLKIKETPKNYYNADERLQQALEAIQQFDLDLDETLRKLNESELKDFDVSLRMMKGSA
                     QASEANTTN"
     gene            2564..3856
                     /locus_tag="TVB59_001432"
     CDS             2564..3856
                     /locus_tag="TVB59_001432"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000205037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEL1010316.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSSDAEVIARYQGGDNAGHTIV
                     IDNKKFKLHLIPSGIFFPEKISVIGNGVVVNPKSLVKELAYLHEEGVTTDNLRISDRA
                     HVILPYHIKLDQLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDRDIFAERL
                     KTNLAEKNRLFEKMYDSAPIAFDEIFEEYYAYGQEIKKYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREIGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLETVKICVAYDLDGKRIDHYPASLEQLKRCKPIYEELPGWSEDITGVRSLEDLPEN
                     ARNYVRRIGELVGVRISTFSVGPGREQTNILESVWATI"
     gene            complement(3971..4744)
                     /locus_tag="TVB59_001433"
     CDS             complement(3971..4744)
                     /locus_tag="TVB59_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEL1010317.1"
                     /translation="MTTKGIVFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCANPESQK
                     TLPEKMLSTDGLKTEIVGQEKTVEEIIAEVLKDLDFYEESGGGMTLSGGEIFAQFDFA
                     LALLKAAKAEGLHTAIETTAFAKHEQFAELINYVDFIYTDLKHYNRLKHTKVTGVRND
                     LIIKNIHYAFEMGKEVVLRIPVIPNFNDSLEDAKAFSELFNQLNINQVQLLPFHQFGE
                     NKYKLLGRSYDMADAVAYHPEDLVDYQQIFLNHHIHCYF"
     gene            4869..5615
                     /locus_tag="TVB59_001434"
     CDS             4869..5615
                     /locus_tag="TVB59_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEL1010318.1"
                     /translation="MNRLEKIIQLVFQKKKIDVNTLSEQLQVSKVTIRKDLDKLESKG
                     LLRRVHGYAVLNSGDDLNVRLSYNYNIKRRIAEKAAELVQDNDTIMIESGSTCALLAE
                     VLCQTKQNIKIITNSCFIASYIRQYSSCQLILLGGYYQPNSEVTVGPLLKEMISLFHV
                     DRVFVGTDGFDPAIGFMGKDMMRSEGVRYMAEASEELIILTDSSKLSKPSLVHQLSLE
                     AVDRMITDEQLEASTYKLLQEHGIAIDFIS"
     gene            5630..6610
                     /locus_tag="TVB59_001435"
     CDS             5630..6610
                     /locus_tag="TVB59_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEL1010319.1"
                     /translation="MKEGRKRLLAKVAYLHYVQGKSQTAISKQMNIYRTTVCRMLAKA
                     RAEGIVRIEIADYDANLFALEEYVRQKYGLEKLDIVSNQMEDSPSDTLVKVAKTAAEV
                     LRSTVKDGDKIGLSWGATLSSLIDELDPKVMKDIMVCPLAGGPSHINAKFHVNTLVYR
                     LARIFHGNSSFINAMVVQKDKQLTRGILQSKYFEETLTYWNHLDLALVGIGGEPNGHQ
                     TSQWRDLLTDKDYKQLADDKAVGEVCCRFFDQEGHSVHQELQDRTIGISLEQLARVPK
                     TIAVAVGQAKAKAILAALKAKFINYLITDKATIMAVLALDQDQTADTYLS"
     gene            6849..7169
                     /locus_tag="TVB59_001436"
     CDS             6849..7169
                     /locus_tag="TVB59_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEL1010320.1"
                     /translation="MELIVPDQIIMGLILNAGDAKQHIYQALKLAKAKDYEASDKELA
                     LADDALLEAHNLQTQFLAQEASGAKADITALFVHSQDHLMTTITEINFIKEIIELRKE
                     LAEN"
     gene            7194..7502
                     /locus_tag="TVB59_001437"
     CDS             7194..7502
                     /locus_tag="TVB59_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1010321.1"
                     /translation="MIKIGLFCAAGFSTGMLVNNMKVAAEKKGIACEIEAYSQGKLAD
                     YAPAIDVALLGPQVAYTLDKSEVICKENGIPIAVIPMADYGMLDGDKVLDLALSLIKE
                     "
     gene            7513..8817
                     /locus_tag="TVB59_001438"
     CDS             7513..8817
                     /locus_tag="TVB59_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL1010322.1"
                     /translation="MANMNAQKIIAPIMRFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     AGQIPFQGVNDAIASVLGADWTEPFMQVYQGTFAIMGLISCFSIGYSYAKNSGVEPLP
                     AGVLSLSAFFILLRSSYVPKKGEAIGDAISKAWFGGQGIIGAIIIGLVVGAIYTAFIR
                     RHIVIKMPEQVPWAIAKQFEAMIPAFAIFILSMLVYIIAKLVTGGGTFIEMIYAVIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGIVTALLLSNLDANKALLAAGDLS
                     LAKGAHIVTQQFLDSFLILSGSGITFGLVIAMIFAAKSKQYKALGKVAAFPALFNVNE
                     PVVFGFPIVMNPVMFLPFILVPVVAALIVYGSIAIGFMQPFAGVTLPWSTPAIISGFM
                     VGGWQGALVQALILVLSTVIYFPFFKVQDNIAYQNELAAEKA"
     gene            9098..11515
                     /locus_tag="TVB59_001439"
     CDS             9098..11515
                     /locus_tag="TVB59_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEL1010323.1"
                     /translation="MTEAKNPYFGTLTERMHRYREAVLDKKPYIDAERAILATEAYQK
                     HQNKPSNLKRAYMLQNILENMTIYIEDESLIAGNQASSNKDAPIFPEYTLEFVLNELD
                     LFEKRDGDVFYITEETKQQLRELAPFWENNNLRARCGVLLPKEVQVYMETGFFGMEGK
                     MNSGDAHLAVNYQKLLEVGLKGFEERTRAAKAALDLTIPESIDKYHFYDSVLIVIAAV
                     KAYAERYAKLARELAKTANPERQAELLEIARICDKVPYQPAETFAEAVQSVWFIQCIL
                     QIESNGHSLSYGRFDQYMYPYAKADLEAGRETEDSIVERLINLWIKTLTINKVRSQAH
                     TFSSAGSPLYQNVTIGGQTRDKQDAVNPLSYLVLRSVAQTKLPQPNLTVRYHKGLDNR
                     FMNECIEVMKLGFGMPAMNNDEIIIPSFIKKGVLEEDAYDYSAIGCVETAVPGKWGYR
                     CTGMSYINFPKILLITMNDGIDPASGKRFATGHGHFKDMTSYDELKAAWDATLREITR
                     MSVIVENAIDLGLEREVPDILCSALTDDCIGRGKTLKEGGAVYDYISGLQVGIANLSD
                     SLAALKKLVFEEGRLTTDELWHALETDFAGERGEEIRQMLINDAPKYGNDDDYADSLV
                     VEAYDTYIDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGKGTLATPDGRHAGTPL
                     AEGCSPEHSMDKKGPTSVLKSVAKLPTDEIVGGVLLNQKVNPQTLAKEEDKMKLMALL
                     RTFFNRLHGYHIQYNVVSRETLIDAQKNPEKHRDLIVRVAGYSAFFNVLSKATQDDII
                     ERTEHTL"
     gene            11530..12198
                     /locus_tag="TVB59_001440"
     CDS             11530..12198
                     /locus_tag="TVB59_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEL1010324.1"
                     /translation="MEYMLDTLNLEAIKKWNRILPLAGVTSNPSIAKKEGDIDFFERI
                     REVRAIIGDKASIHVQVVAQDYEGILKDAAAIRQQCGDSIYVKVPVTTEGLTAIKTLK
                     VEGYHITATAIYTTFQGLLAIEAGADYLAPYYNRMENLNIDPEAVIGQLAEAIDRECS
                     DSKILAASFKNVAQVNRAFALGAQAITAGPDVFEAGFAMPSIQKAVDDFGKDWQAIHH
                     RQTI"
     gene            12323..13414
                     /locus_tag="TVB59_001441"
     CDS             12323..13414
                     /locus_tag="TVB59_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEL1010325.1"
                     /translation="MKVFASPSRYIQGKNALFTNSDIIKKLGQKPVLLCDDIVYGIVG
                     ERFEGYLSEHGLPPVHVAFNGEASDNEINRVVAIARENDNDVIIGLGGGKTIDSAKAI
                     ADILEIPVIIAPTIASTDAPTSALSVIYTDEGAFEKYIFYAKNPELVLVDTQVICQAP
                     KRLLASGIADGLATWVEARAVMQKNGDTMAGGNQTLAGLAIAEACERTLFADGLKAMA
                     SCEKKVVTPALENVIEANTLLSGLGFESAGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLTQLFLENKSREEIDRYVDFYQAIGMPTTLKEMHLDTATEEDFLKIGRQATMAGE
                     TIHQMPFTITAEDVASALVAVDAYVCSRT"
     gene            13921..14973
                     /locus_tag="TVB59_001442"
     CDS             13921..14973
                     /locus_tag="TVB59_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEL1010326.1"
                     /translation="MIRKIGIVSLSSGMLGEANVKHELDLGLARLKQLGLEVTILPNA
                     LKGIDYFDQHPEARAADMIQAFADPSIDMILCAIGGVDTYRLLPYLFIEHQLQDVVNQ
                     KVFLGFSDTTINHLMLHKLGIKTFYGQSFLADICELADDMLPYSLAYFKELLETGTIA
                     EIRPSEKWYEERTDFSANSLGTQRIAHRNQGFELLKGPSLFKGEILGGCLESLYKLLD
                     SSKCSDSAKLCEQYQLFPDLSDWAGRLLLLETSEDKSDPAQYRRMLETLKATGIFSVI
                     SGLLVGKPIDNSYYDDYKQQLLAVVDNDIPILYNVNVGHATPRAIVPFGVMAVVDAKE
                     QVIRFVPDEHTDQNDV"
     gene            15002..15580
                     /locus_tag="TVB59_001443"
     CDS             15002..15580
                     /locus_tag="TVB59_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEL1010327.1"
                     /translation="MPKVDTITQVYFIRHAEPNYQNHNDVTRELSEHGVKASQDLVRQ
                     LAEVSIDAFYSSPYKRSIDTIAPLAASRAMEIKLIDDLRERKLADAWIEDFVDTAKKQ
                     WDDFTFKLPTGESLQEVQDRNIAALNRILKEAKGKTVVIGTHGTALSTLINYYQPDFG
                     FEDFDRYKHVFPWIVRASFDGDKLLGLNEFLV"
     gene            15779..16687
                     /locus_tag="TVB59_001444"
     CDS             15779..16687
                     /locus_tag="TVB59_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1010328.1"
                     /translation="MTNKTKRTGLVRKYGACSAAIALAALASLGAGKAVKADQPAALK
                     YPEPRDYFLHTREGDVIYDEDIKRYFEDLEAYLTARLGGIDKKVEEAAQKPGIPGPTG
                     PQGPKGDKGDPGAPGERGPAGPKGDTGEAGPRGEQGPAGQAGERGPKGDPGAPGPKGE
                     KGDTGAVGPKGEKGDTGATGPKGDKGERGEKGEQGQRGEKGEQGQRGEKGEQKPKGDQ
                     GKDTKPSAPKAPEKAPAPKAPKASEQSSNPKAPAPKSAPSKSAAPTGQKAALPATGEI
                     NHPFFTLAALSVIASVGVLTLKGKKD"
     gene            complement(16923..18269)
                     /locus_tag="TVB59_001445"
     CDS             complement(16923..18269)
                     /locus_tag="TVB59_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1010329.1"
                     /translation="MKKNQVTRYSLLIPAALMAAGLAMSTNSSVAFADESPAVDNHTV
                     VQPRLGEDKDTADTANQQLSDSTEVMADKPITKASETANPVAAADKLPLDTNQSAEDI
                     IAVKKAYIAKNTGLPLDKIQLLDTSEGKALMYPHDDHHHVILLDKIDVSKPFDDGQSS
                     HHSDHAHHHHDDVIEGSFAFTATVIDPEGKVLSGKDVQVVDITSGRKTLATVTTDEKG
                     QAVFDKLPLGRSLSIFVNGVPQGYTVRTGVDGDKHSASFTVDGKGTVEPEYSKTPLVV
                     IVRNEDAEPLSGQEVTLKHRVGRVIEKVTTGADGKAVFSKGLLDGTFYEIFVNGKKLS
                     QATTGEERSVALDAKDIKKSSPHSKPQEDAPKVPETKPETKPEAKPLSPEKADQAGKV
                     AAPAHTASKAAAAKAEMKKTTNQLPATGEAVNPFFTAAALAVMATAGVAAIKRKEN"
     gene            complement(19309..19413)
                     /locus_tag="TVB59_001446"
     CDS             complement(19309..19413)
                     /locus_tag="TVB59_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019773529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL1010330.1"
                     /translation="MTAFEVVQILLGFSSFTIALISLCYQIFKDDNKK"
BASE COUNT         5583 a         3995 c         4475 g         5751 t
ORIGIN      
        1 tgacagaagg gtatttttga ttgttaccaa tcaaaaagcc acaggctggg tagctgtggc
       61 aggtctgtta tatcaggagc tgctttaagg ctggcgttct gtctgctcga ttgtctcctg
      121 cttttctttg ccctcattga ggagagcttg aatgatgctt tggtcgcgca gcttgacaga
      181 atcattaatg gtttctgctg atttgataat ggctgcttcc agctgagctc gctccttgcg
      241 tccttgatca atggcagcaa tgatgccgtt gttctgggca actagacttt ctgctagtgc
      301 tgtcactgag gtcaacgaaa tcgttgggct ttgagctgtc cgctcaaggt ttggaatcgc
      361 ttccttgctt gtctcagcta gcatttgtag ggcagcgttg ttggcattga caatggcgtc
      421 tgcggtcatt ccagacttga cagactgctg catgatacct agctgagcaa tagataattt
      481 catggttgga atggtattgc gtcgcagcat gcctagcttt tgtcgcatgt cagaggacac
      541 cttgacgagg ttacgcattt gcggtgttgt tgcccaagcc acatagagtc gactaaggta
      601 ttcggtgtgc tgctgctcaa gggtattgag cacctctgtt gtcctagcca ataggtcaga
      661 ttgcacctga tactctggtg ttgtcgtgtc aagtactgca agctcctgct gcaaggtaag
      721 ggcgcggcta gaggtttcct tttgactagc ttcaagaaag gcaatcacac caaccagatt
      781 ttcaatcgac ttggtattgt cctcaatcaa gagctctgcg gctacaatat tacgagcaag
      841 cgtgtcttct tgcttgacaa cagctgcagc cataccgtcc attttttgct caatggtctg
      901 agaatcaaag taaaattcct gaagcgtgtt cttgctttgt ttgaatagct tttgcaaaag
      961 cgttggcttt ttttcaagct cagcagcggt cgcttcctta tatttggcaa taaaaccatt
     1021 aagctcacga ttggtgtttt tgaggagctc gtcaacctgt ggaatttgta atttcttttg
     1081 ctcagctaga atatgattaa cagtagcatt aactccttca acggctgctt gaccaaaatc
     1141 aagtaaggca ttttggtcct ccataaaggt atcaacaagt gctggtgcct ttgcagtgat
     1201 agcctgctgc tgctcaggac tcagcttttc gtagaaagaa atttgtccag tagtattggt
     1261 tggtagctta gtgataatat cggtggtttt atctgtttta gtgatagcat tattagcgat
     1321 ctggtcaata tcaaagtgaa attctgccat aatagctcct ttatcagttg gtagtgttag
     1381 cctcgctagc ttgagcagag cccttcatca tgcgcagact aacatcaaaa tcctttagct
     1441 cactttcgtt aagcttcctt agggtctcat caaggtccag gtcaaattgt tggatagcct
     1501 caagagcctg ctgcaagcgc tcatcagcat tgtaataatt tttaggtgtt tctttgattt
     1561 ttaggtagcc ctgcaaaatg tcttgaaacc tgcgcatatt agcctcatgg agtgctaaga
     1621 gttcctcgtg attatcagct cccttgattt tttctaaaat cgagtggtgg tcagcctgga
     1681 tattgtcata atagtgacgt agctcgggcg ccttataaat ggggtcagct gcctgctcct
     1741 ttaggctttc agccttcaga tttgctgcga tttgaatctt ttcgagctgt agctgcacat
     1801 cgctttccac gtcattagcc tttttggtca cacgacggta aatgctaata tccatgtgtt
     1861 ccttgaggtg accgctttct tttttgattt cactcaattg cggcagtagc tgcttggcta
     1921 aaatggcata ctgtgtaaaa tcttccttag ccagataatg atcaaggagc ttaacctttc
     1981 ggtcggcaag ctgaatagtt gcctttaaat cctccaagcg tttctcaagt gttgccgttt
     2041 ttaagcgagc ctgacggttc gaatagcgat aagcagcata accaacaccc agcgctgcaa
     2101 aaatcagaac agctttgtca atattttcta caactcctac taaaatcgcg aagcctatca
     2161 gccagccaaa ccagctaaag ccctttcttc gtcgagatac ttggtaatat tttcgtgaca
     2221 tgtaaaactt cctttgtact ttttatcaca gtaaacaatc aattagttct attttacctt
     2281 aaaaatgtga tttcttaaag gaaagattag cagatttagc attattttcc ttcaaagact
     2341 ggtcttgctt gctttttagt gaaatgtttg ctttctgcct gttttcagaa aaaagcattt
     2401 gccatttgat attttttctt aataatacca aggaaagata gcagaaaacc acattttttg
     2461 ctataatgag gtgtaacaga cacttgcagg tgagagtcct gccacattta tcaagaaagg
     2521 tgggggctct ctttctttgt tgagatgagc ctatatcgaa gatatgacat cagtagtagt
     2581 agttggtacc cagtggggtg acgaaggtaa gggtaagatc actgactttt tatcctcaga
     2641 tgcagaagtg attgcacgtt accaaggtgg tgacaatgca ggacatacca ttgttattga
     2701 taacaagaaa ttcaagctgc acctgattcc atcaggtatt ttcttcccag aaaagatttc
     2761 tgtgattgga aatggtgtgg ttgtcaatcc aaaatccttg gttaaggagc ttgcttacct
     2821 gcatgaggag ggcgtgacca cagacaattt gcgcatttct gatcgtgctc atgtcatttt
     2881 gccataccat atcaagcttg accagcttca agaggaagca aagggtgaca ataaaatcgg
     2941 taccaccatc aagggcatcg gtccagccta tatggataag gcagcacgtg ttggtatccg
     3001 tattgcagac ctgttagaca gggatatttt tgctgagcgc ttaaagacga atctggctga
     3061 gaaaaatcgt ctttttgaga aaatgtatga cagcgcaccg attgcatttg acgagatttt
     3121 tgaagaatac tatgcttatg gtcaagagat caaaaaatat gtgacagaca catctgttat
     3181 tttgaacgac gctcttgatg cgggcaagcg tgtccttttt gagggagctc aaggggttat
     3241 gcttgatatt gatcagggaa cctatccatt tgtcacctca tctaatccag ttgcaggcgg
     3301 tgtgaccatt ggttcaggag tcggaccaag caaaatcaac aaggttgttg gagtatgtaa
     3361 ggcctatact agtcgcgttg gtgatggacc attccctacc gagttatttg acgaggttgg
     3421 tgagcgcatt cgtgagattg gtcatgagta tggaacaacc actggtcgtc cacgtcgcgt
     3481 tggctggttt gattctgttg tgatgcgtca tagccgtcgt gtgtcaggca ttaccaatct
     3541 atcacttaac tctattgatg tgctatcagg ccttgagact gtaaaaatct gtgtcgctta
     3601 tgaccttgat ggtaagcgca ttgatcatta cccagcaagc cttgagcagc taaaacgctg
     3661 caaaccgatt tatgaagagc ttccaggctg gtcagaggat attaccggtg ttcgcagcct
     3721 tgaggatctc ccagaaaatg ctcgcaacta tgttcgtcgt attggcgaac tggttggtgt
     3781 tcgtatctca accttctcag taggtccagg acgtgagcaa accaatatcc ttgaatctgt
     3841 ttgggcaact atctaagctg tctattgtga tagcaccagc cttagctgaa tattaacgaa
     3901 aacacgagca atcctaagga aggttatccg gaggagctgc tcatgttttt taggtatagg
     3961 gcttttaaga ttaaaaatag caatggatat gatgattgag aaagatttgc tgataatcca
     4021 ccagatcctc tgggtgataa gcgacagcat cagccatgtc atagcttctg cctagcaatt
     4081 tgtatttgtt ttcaccaaac tggtgaaagg gaagtagctg cacctgatta atgtttagct
     4141 gattgaaaag ctcagaaaat gccttggcgt cctccaaaga atcgttgaaa ttcggaatga
     4201 cagggatacg caagacgact tccttgccca tctcaaaggc gtagtggata tttttaatga
     4261 tcaggtcatt tcgcaccccg gtgaccttgg tgtgctttag gcgattatag tgcttcaaat
     4321 cggtataaat aaagtctaca tagttgatca gctcagcaaa ttgctcgtgc ttagcaaagg
     4381 ctgtcgtttc gatagctgtg tgtagccctt ctgccttagc agcctttaga agcgctaagg
     4441 caaagtcaaa ttgagcaaag atttcaccgc cagacaaggt cataccaccg ccagattcct
     4501 cgtaaaaatc aagatccttt aaaacctcag caataatctc ttcaaccgtc ttttcctgac
     4561 caacgatttc tgtctttagt ccatctgtgc ttagcatttt ttcgggtaac gttttttgtg
     4621 attcgggatt ggcacaccag ggacagcgta agggacaccc cttgagaaat acagttgtgc
     4681 gaatgcctgg tccatcgtgt atgctaaaat gctggatatt aaatacaatg ccttttgtcg
     4741 tcatagcgag acttcctttc gttctaggac tatcataaca gataaacgta aataaatcaa
     4801 ttacgaacga aagttatttt tgcttttcat ttaccgccat aattgttaca atggaaagga
     4861 ggtaaattat gaatcgttta gaaaaaatta tccaattagt atttcaaaag aaaaaaatag
     4921 atgttaatac tttatctgag cagctacagg tctccaaggt aaccattcgt aaggatttag
     4981 acaagcttga aagtaagggg ctgctgcgtc gtgtgcatgg ctatgcggtg ctcaatagtg
     5041 gtgatgattt gaatgtgcgc ctgtcctata attataacat caaaaggcgg attgctgaaa
     5101 aggctgccga gctggtgcag gacaacgata ctatcatgat tgagtcagga tcgacctgtg
     5161 ccctgttggc agaggtgctc tgtcaaacca aacaaaacat caaaatcatc accaactcct
     5221 gctttattgc aagctacatt cgtcagtata gtagctgtca gcttatcctg ctggggggct
     5281 actatcagcc taattctgag gtgaccgtag gcccactttt aaaggaaatg atttcgcttt
     5341 ttcatgtgga tcgtgttttt gttgggacag atggctttga tccggcaatt ggctttatgg
     5401 ggaaggatat gatgcgctca gagggcgtcc gttacatggc agaggcttct gaggagctta
     5461 ttatcctgac agattctagc aagcttagca aacccagtct ggttcatcag ctatcgcttg
     5521 aggctgttga ccgtatgatc acagatgagc aattggaggc aagcacctat aagctcctgc
     5581 aagagcatgg tattgccatt gactttatat cgtagcgtag ggaactcaaa tgaaagaagg
     5641 acgtaaacgc ctgcttgcca aggttgccta cctgcattat gtgcagggca aaagccaaac
     5701 cgctatttca aagcaaatga atatttaccg aacaacggtc tgtcgcatgc ttgccaaggc
     5761 tagggctgaa ggcattgtgc gtatcgagat agctgattat gatgctaatt tgtttgcctt
     5821 ggaggagtat gttcgtcaaa aatatggctt agaaaagctt gatattgtat ccaatcaaat
     5881 ggaagatagc cctagtgata ccttggtaaa ggtggccaaa acagcagccg aggttttgcg
     5941 cagtacggtc aaggatggtg ataagattgg cttatcgtgg ggggcaacgc tgtcaagtct
     6001 gattgacgag ctggatccta aagtaatgaa ggatattatg gtgtgtccct tggctggtgg
     6061 tcctagtcat atcaatgcca agtttcatgt gaatactctg gtttatcgct tagcaaggat
     6121 ctttcatggc aatagctcct ttatcaatgc tatggtggtt cagaaggaca agcagctaac
     6181 cagagggatt ttgcagtcca agtattttga agaaaccctg acctattgga accatcttga
     6241 ccttgctctg gtcggtattg gaggagagcc aaatggtcat cagaccagtc agtggcgtga
     6301 tttgttgact gataaggact ataagcagct ggcagatgac aaagctgttg gtgaggtctg
     6361 ctgtcgcttt tttgatcagg aggggcatag tgttcatcag gaattgcaag acagaacgat
     6421 aggcatttca ctggaacagc tcgcgcgtgt gcctaagaca atagctgttg ctgttggtca
     6481 agctaaggcc aaggctattt tagcggcttt aaaggctaaa tttatcaatt acctcatcac
     6541 cgataaggct actatcatgg ctgtcttggc tttggatcag gatcagacag ctgacaccta
     6601 tctctcatag caatagctta atcagaagac gattgttttc tgattttttt gtgaccaaaa
     6661 atcttgcaaa gcatcacttt tgcacaatag tgctaaaaaa taaatacagc acacaatata
     6721 ttgacgaagg aagtaaaaat gataaaatga acttatcaaa gaaatgtaaa cgattacaaa
     6781 cgcaagctgt ttttttacga aaaaagcaag ggtaatcctt acatgagcac gtcacaaagg
     6841 agaaacaaat ggaattaatt gtaccagacc aaatcatcat ggggttaatc ctaaatgcag
     6901 gagatgcaaa gcagcatatc tatcaagccc taaagctggc taaggctaaa gactatgagg
     6961 ctagtgacaa ggagttagcc ttagctgatg atgctttatt agaggcgcat aatttgcaga
     7021 cacaattttt agctcaggag gctagcgggg caaaggcaga cattacagcc ttgtttgtcc
     7081 attctcagga tcacttgatg acaactatta cagaaatcaa ttttatcaaa gaaatcattg
     7141 agcttcgtaa ggaattagca gaaaactaaa gatcatatca aaaggaggac gttatgatta
     7201 aaattggctt attttgtgca gcaggctttt caacaggcat gcttgtgaac aacatgaagg
     7261 tggctgctga gaaaaagggc attgcttgtg agattgaagc ctactcacaa ggaaagctgg
     7321 cagactatgc accagctatt gatgttgccc tcttaggtcc acaggtggct tataccttgg
     7381 ataagtcaga ggttatctgt aaggaaaacg gcattccaat agctgttatc ccaatggctg
     7441 attatggtat gctagatggt gataaggtgc ttgacttagc gctcagcttg ataaaggaat
     7501 aggagcttgg tcatggctaa tatgaatgct caaaaaatca ttgcaccgat tatgcggttt
     7561 gttaatatgc gtggcattat cgctctaaag gacggtatgc tggcgatttt acccttgacg
     7621 gttgtcggaa gtctttttct tattgcaggt cagattccct ttcagggggt caatgacgct
     7681 atagcgagtg tccttggggc agactggaca gagccattta tgcaggttta tcagggtacc
     7741 tttgctatta tgggcttgat ttcctgcttt tcgattggct attcctacgc taaaaattcg
     7801 ggtgtggagc cactgccagc aggtgtgcta tcattgtcag ccttctttat cctgctaagg
     7861 tcctcttatg tgccaaaaaa gggtgaggct attggtgatg ccattagtaa ggcttggttt
     7921 ggtggtcaag ggattattgg tgccatcatt attggcttgg tggttggtgc gatttataca
     7981 gcctttattc gtcgtcatat cgtcatcaaa atgccagagc aggtgccgtg ggccattgcc
     8041 aagcaatttg aagcgatgat tccagccttt gcaatcttta tcctgtcaat gcttgtttat
     8101 atcattgcaa agctagtgac aggtggcggc acctttattg aaatgattta cgctgtgatt
     8161 caggtgcctc tacagggctt gactggctct ctttacggtg cgattggtat tgcctttttc
     8221 atctccttcc tatggtggtt tggtgtgcat gggcaatcag tggtcaatgg tatcgtgaca
     8281 gcgctgctct tgtcaaatct agatgctaac aaggccttgt tagcagcagg tgatttgtct
     8341 ttggctaagg gtgctcatat tgtgacgcag caatttttag attctttctt aattttatca
     8401 ggctcaggta ttacctttgg cttagtgatt gccatgattt ttgcagccaa atcaaagcag
     8461 tacaaggctc taggcaaggt agcagccttt ccggctctct ttaatgttaa tgaaccggta
     8521 gtctttggct ttccaattgt gatgaaccca gtgatgtttc tgccatttat tttggtgcca
     8581 gttgttgcgg ctctgattgt ttatggctct attgcgattg ggtttatgca gccatttgca
     8641 ggtgtaacac ttccttggtc tacaccggct attatctcag gctttatggt tggtggctgg
     8701 cagggggctc ttgttcaggc tttgattctt gtcttgtcaa ccgttattta cttcccattc
     8761 tttaaggttc aggataatat tgcttatcaa aatgaattgg cagctgaaaa agcttaacag
     8821 tatgctgata tcaatcacca tgacttaaaa acagtcttta gtcactagct atagcattcc
     8881 tagagaaggg cttagagaag gaggatttct tcacgtaacc atctcaatga ggtggttttt
     8941 ttgaaagaga ctcttagaca agtctatttt tgcacgatag tgcaacttta aatgaatagc
     9001 tgaatgctat ggatatgata ggcaaaatgt tttaaatatg gtaaaataat tacgaaagaa
     9061 agtaatttaa tttcgtaaga aacaaaggag gcctaatatg actgaagcaa agaatcccta
     9121 ttttggtaca ttaacagaaa gaatgcaccg ctatcgtgag gcagttctag ataaaaagcc
     9181 ttatattgat gctgagcgtg ctattttagc aacagaggct taccaaaaac accaaaacaa
     9241 gccatctaat ctaaaacgcg cttacatgct gcaaaatatt ttggaaaaca tgaccatcta
     9301 cattgaggac gaaagcttga ttgctggtaa tcaggcgtct tctaacaagg atgcacctat
     9361 ctttccagag tacactcttg aatttgtcct aaatgagctt gacctttttg aaaagcgtga
     9421 tggcgatgtg ttttacatca ctgaagaaac caagcagcag cttcgcgagc ttgcaccctt
     9481 ctgggaaaat aacaatttgc gggcccgctg tggtgtcttg ctgccgaaag aggttcaggt
     9541 ttatatggaa actggcttct ttggcatgga aggcaagatg aattcaggag atgcccattt
     9601 agctgtcaat taccaaaagc tattagaggt tggcttgaag ggctttgagg aacggactcg
     9661 tgctgccaag gctgcgcttg atttgactat tcctgaaagc attgataagt accattttta
     9721 tgattctgtt ctgattgtga ttgctgcggt taaggcttat gcagagcgct atgccaaatt
     9781 ggcgcgtgag ctggccaaaa cagctaatcc agagcgtcag gcagaattgc ttgaaatcgc
     9841 gcgtatctgt gacaaggtgc cttaccagcc ggcggaaacc tttgctgaag cggtccaatc
     9901 agtttggttt atccagtgta ttcttcagat tgagtcaaat gggcattctc tttcttatgg
     9961 ccgatttgat caatacatgt atccatatgc caaggctgat ttggaggctg gtcgtgaaac
    10021 agaggattct atcgttgagc gcttgattaa cctttggata aagactctga ccatcaataa
    10081 ggtacgcagt caggctcata ccttctcatc agcaggtagt ccgctgtatc aaaatgtcac
    10141 cattggtggg caaaccagag ataagcagga cgctgtaaat cctctatcct acctagtgct
    10201 tcgcagtgtg gctcaaacca aattaccaca accaaaccta accgttcgat atcacaaggg
    10261 cttggataat cgttttatga atgaatgcat tgaggttatg aagcttggct ttggtatgcc
    10321 agctatgaac aacgatgaaa tcatcattcc gtcctttatc aaaaagggtg tccttgaaga
    10381 agacgcctat gattattcag caattggctg cgttgagaca gccgttccag gtaaatgggg
    10441 ctatcgctgt actggtatga gctacattaa ctttccgaag attttgctta tcaccatgaa
    10501 tgatggtatt gacccagctt cgggtaagcg ctttgcaaca ggacatggtc acttcaagga
    10561 tatgacctct tatgacgagc taaaggcagc ttgggacgcg actctgcgtg aaatcactcg
    10621 catgagtgtc atcgtagaaa atgccattga ccttgggctt gaacgagagg tgccagacat
    10681 tctttgctct gcattgaccg atgattgtat cggccgaggc aagacgctca aagaaggtgg
    10741 agcagtctat gactacatct caggcttgca ggtggggatt gctaacctgt ctgattccct
    10801 agctgcactg aaaaaattgg tgtttgagga gggtcgccta accactgatg agctctggca
    10861 tgctctagaa acagactttg caggtgagcg tggtgaagag atccgtcaaa tgctgattaa
    10921 cgatgcacca aaatatggta atgatgatga ctatgctgat agcttagtgg ttgaagccta
    10981 tgatacctac attgatgaaa ttgctaaata ccctaatacg cgctacggac gtggtccgat
    11041 tggtggtatt cgctactcag gcacctcatc tatttcagct aatgtcggcc aaggtaaggg
    11101 aaccttagct accccagatg ggcgtcatgc aggaacaccg cttgctgagg gctgctcacc
    11161 agagcacagt atggataaaa aaggaccaac ttctgttttg aaatccgttg ccaaattgcc
    11221 aacagatgaa attgtaggtg gggtcttact caaccaaaag gttaatcctc agacactagc
    11281 aaaagaagaa gacaagatga agctgatggc tctgcttcgg accttcttta acaggctaca
    11341 tggctatcat attcaataca acgtcgtctc acgtgaaacg cttattgatg ctcaaaagaa
    11401 tcctgaaaag caccgcgact tgattgtgcg tgtggcaggc tattcagcct tctttaatgt
    11461 tttatcaaaa gccactcagg acgatatcat cgaacgtacc gaacacacac tataggagaa
    11521 caattactta tggaatacat gctagatact ctaaatctag aggctattaa aaagtggaat
    11581 cgcattttac cccttgcagg ggtaacctca aatccttcaa ttgctaaaaa agagggagat
    11641 attgattttt ttgaacgcat tagagaggtt cgtgcgatca ttggagataa ggcctctatt
    11701 catgtgcaag tcgtggcaca ggattatgaa ggtattttaa aggacgctgc ggctattcgt
    11761 cagcaatgtg gtgatagtat ttatgtaaag gttcctgtga caacagaggg actcacagcg
    11821 atcaaaaccc taaaggtaga gggctaccat atcacagcta cagccatcta tactaccttc
    11881 caaggcttac tggccatcga agcaggagca gattatctgg caccttacta caatcgcatg
    11941 gaaaacctca atattgatcc ggaggctgtg attggccagc tggcagaggc cattgatcgt
    12001 gaatgctctg atagtaaaat cttggcagcg agcttcaaaa atgtagctca ggtcaaccga
    12061 gcctttgctt tgggtgctca ggccatcact gctggtccag atgtctttga ggcaggcttt
    12121 gcgatgccat ctatccaaaa ggctgtagat gattttggca aggattggca agccattcat
    12181 catcgtcaaa ctatttaaaa gccatctaac ccatcgttat atgagcaaga gcagggacgc
    12241 ttctatcagc atagctagac tagtcttgct cactcttaga tggtgagaag cgtcaaaaat
    12301 ctgatttaga aagaggaaca tcatgaaagt atttgcaagt ccatcacgct atattcaagg
    12361 gaaaaatgcc ttatttacca atagtgacat catcaaaaag ctagggcaaa agccggtatt
    12421 gctctgtgat gatattgttt acggcattgt cggagaacgt tttgagggct atttaagtga
    12481 gcatggtcta ccacctgttc acgtagcctt taatggcgaa gcgtctgata atgagattaa
    12541 tcgtgtcgtt gccattgcta gagaaaatga taatgatgtc attatcggac ttggcggagg
    12601 caagaccatt gacagtgcca aggcaatcgc tgacatcttg gagataccag tgattatcgc
    12661 tccaaccatt gcctccactg atgctccaac atcagcccta tcagtgattt acacagatga
    12721 gggcgccttt gaaaaataca ttttctatgc taaaaatcct gagcttgtct tggttgatac
    12781 tcaggttatc tgtcaagcac caaagcgctt gctggcttca ggtattgctg atggtctagc
    12841 cacttgggta gaagcgcgtg cggttatgca aaaaaatggt gacacgatgg caggcggcaa
    12901 ccaaaccttg gcaggacttg ctattgctga ggcctgcgag cgtaccctgt ttgctgacgg
    12961 tctcaaggca atggctagct gtgagaaaaa ggtcgttact ccagctttag aaaatgtgat
    13021 tgaggctaat accttattaa gtggtcttgg ctttgaaagt gcaggacttg ctgctgctca
    13081 tgctattcac aatggcttta cagctttgac aggtgacatt catcacctca ctcatggtga
    13141 aaaggtggcc tatggcaccc taacacagct tttcctcgaa aataaatcaa gagaagaaat
    13201 tgaccgctac gttgactttt atcaggctat cggaatgccg acaaccctaa aagaaatgca
    13261 tttagacacc gccaccgaag aggatttctt aaaaataggg cgtcaagcaa ccatggcagg
    13321 agaaaccatt caccaaatgc catttaccat cacagcagag gacgttgcct cagcgcttgt
    13381 tgctgtagat gcttacgttt gcagcagaac ttaatgcaga actgctaaag ttctcttagc
    13441 cttatcagga gcctattgct ggtagctctt gaccaaagga ttgtacctac cttagcctta
    13501 attcaactgt tagaggtgtt cctcttgctg tggtaagaga ggttctttac tgctaaaggc
    13561 tcattctcag ggcaagctgg cccctccaaa tcatttaaaa agtcgtaaat ctaatcaata
    13621 atggctatca gtataggcta ctggtagtca ttattctata tctgatttat gagaacatac
    13681 cagtcagcag ctttgctgtg ccacctattt cttgtcatta cagtagctta gctttatagc
    13741 tgacagagca aatgcttcct catctattag ctcttaattc aaccgctaca gtaatagaaa
    13801 aagctaatca aagtaagggc tagttttttt tggtatcgct attaacagta tgtattagag
    13861 gctatcagcc tagccattat tgtggtataa tgacacaaca actttttaag gaggttagct
    13921 atgattcgga agattggtat tgtcagcttg tctagtggta tgcttggcga ggctaatgtc
    13981 aagcacgaat tggatttagg cttagcccgt ttaaaacagc taggcttaga ggtaacgata
    14041 ctcccaaatg ctttaaaggg catagactat tttgatcagc accctgaagc aagggcagca
    14101 gatatgattc aggcctttgc agatccgtct attgacatga ttttgtgtgc cattggtggg
    14161 gtggatacct atcgcctctt gccctatctg tttatcgaac atcagctaca agatgttgtc
    14221 aatcaaaagg tctttcttgg attttctgac accacgatca accacttgat gcttcataag
    14281 cttggtatta aaacctttta tggtcagtcc tttcttgccg atatttgtga gctggctgat
    14341 gacatgctgc cttactcgct ggcttatttt aaagagcttc ttgagacagg aactatcgct
    14401 gagatcagac ctagtgagaa gtggtatgag gagcggactg actttagtgc aaacagcctt
    14461 gggacacaga gaatagctca tcgcaatcaa ggctttgaac tattaaaagg tccgtcctta
    14521 ttcaagggag agatactagg tgggtgttta gagtcacttt ataaactatt ggattcgtca
    14581 aagtgttcag atagcgctaa gctctgtgag caataccagc tctttccaga tctgtctgac
    14641 tgggcaggca ggctcttgct tctagaaacc agtgaagaca agtcagatcc agctcaatac
    14701 cgccgaatgc ttgaaaccct caaagcaaca gggatttttt cggtgatctc tggattattg
    14761 gttggaaagc cgatagacaa cagctactat gacgactata agcagcagct gctagctgtt
    14821 gttgataatg atatccccat tctttacaat gtcaatgttg gccatgctac cccaagagcc
    14881 attgttccct ttggtgtcat ggctgtggtt gatgccaaag agcaggtcat tcgatttgtc
    14941 cctgatgagc atacagacca aaatgacgtc taacaaatca aaacagaaag tgagagagtc
    15001 tatgccaaag gttgacacga taacgcaggt ttattttatc cgccacgcag agcctaacta
    15061 tcaaaaccac aacgacgtga ctagagagct ctccgagcat ggggttaagg cgagccaaga
    15121 cctggttagg caactagcag aggtgtcgat tgacgccttt tattccagtc cctataaacg
    15181 ctctattgac accattgccc cactagcagc tagtagggca atggaaatta agctgattga
    15241 cgatttgaga gagcgtaagc tagctgatgc ttggatagaa gactttgtcg acacagccaa
    15301 aaagcagtgg gacgatttta cctttaaatt gccgacaggc gaaagcctgc aagaggtaca
    15361 agacagaaat atagcagctc ttaaccgtat tttaaaagaa gcaaaaggca agacagtagt
    15421 cattggcaca catggcacag cactgtcaac ccttatcaac tactatcaac cagactttgg
    15481 ttttgaggat ttcgaccgat ataagcatgt ctttccttgg atagtcagag ctagctttga
    15541 tggtgacaag ctgcttgggc ttaatgagtt tctagtctga caagtctagc cttgatccag
    15601 ctattatagg tgatgacagc aacaaaatca gataattaac cctttcatta aaaaaaaaaa
    15661 aaacaaaacc tcggagacaa actagccagc agctatttct catgagtaat caacatgtta
    15721 aaatcttctt tggagatatt agacaaccat aattattata tcatcaaagg agagaaagat
    15781 gacaaacaaa acaaagcgta caggattggt acgcaagtac ggtgcctgct cagcagctat
    15841 cgccttagca gctcttgcaa gcctgggagc aggtaaagca gtaaaggcag accagccagc
    15901 agcactaaaa tatccagaac ctagagacta ttttcttcat actcgtgaag gtgatgttat
    15961 ttatgatgag gatataaaaa gatattttga ggatttagaa gcctatttaa cagctagact
    16021 tggtgggatt gataaaaaag tagaagaagc tgcccaaaag ccaggtattc caggtcctac
    16081 tggccctcaa ggtcctaagg gagacaaagg agatccaggt gcccctggtg agcgcggtcc
    16141 agctggacca aagggcgata cgggcgaagc cggaccaaga ggtgagcaag gcccagccgg
    16201 acaagctgga gaacgtggac caaaaggaga tccaggtgct ccaggtccta aaggtgaaaa
    16261 gggtgatact ggtgcagttg gtcctaaagg tgaaaaaggt gataccggag caaccggacc
    16321 aaagggagac aagggcgaac gcggtgaaaa aggcgagcaa ggccaacgtg gcgaaaaagg
    16381 cgagcaaggc caacgcggtg aaaaaggcga gcaaaaacca aagggtgatc aaggaaaaga
    16441 tacaaaacca tcagctccaa aagcacctga aaaggctcct gcaccaaaag ctccaaaggc
    16501 ttcagagcag tcatctaatc ctaaagcacc agctcctaag tcagcaccaa gcaaatcagc
    16561 ggcaccaaca ggtcaaaaag cagccctacc agcaacaggg gaaatcaacc acccattctt
    16621 cacccttgca gctcttagtg tcatcgctag cgtaggcgtc ctaactctaa aaggaaaaaa
    16681 agactaagct agttattgta tctttcctgt atgacactag ctaacagcta atcacaaaca
    16741 ccagagagag gtcttttctg acctctcttt tatatacact gagcacatgc ttacctcaaa
    16801 aagacagtag tctaagtttg actactgtct caaaaatcat ttttatctaa agctttgatc
    16861 agcttgacaa atggtagaga aggacttgat ttctaaggcc tttgacctca gtttgacttt
    16921 tgttaatttt ccttacgttt tatagctgct acaccagctg tagccataac tgcaagtgca
    16981 gctgcggtga agaatgggtt cacagcctca cctgttgctg gcaattgatt agtcgttttc
    17041 ttcatctcag ctttagctgc tgctgcttta gaagctgtgt gagctggcgc tgctacttta
    17101 cctgcttgat cagctttttc aggactgagt ggtttagcct ctggcttagt ttctggtttg
    17161 gtttctggaa ctttaggtgc gtcttcttgt ggttttgaat gtggacttga ttttttaata
    17221 tctttagcat ctagggcaac gcttctttcc tcacctgttg tagcttgaga aagctttttg
    17281 ccgttgacaa aaatctcata gaaagtgcca tctagaagcc ctttagaaaa tacagctttg
    17341 ccatcagctc ctgttgttac tttctctatc acacgaccta ctctatgctt tagagtgact
    17401 tcttgtcctg ataaaggttc agcatcttca ttacgaacga taacaaccaa aggtgtttta
    17461 ctgtattctg gctcaactgt tccttttccg tcaacagtaa agctagctga atgcttgtcg
    17521 ccatcaacac ctgttcgtac agtatagcct tgaggaacgc cattcacaaa aattgataaa
    17581 cttcttccta aaggaagctt gtcaaaaaca gcttgtcctt tttcatctgt tgtcacagtc
    17641 gcaagtgttt ttctgccact tgttatatct accacttgga cgtcttttcc agataatact
    17701 ttaccctcag ggtctataac tgttgcggta aaagcaaagc taccttcaat aacatcatca
    17761 tgatggtggt gtgcatgatc actgtgatga ctactctgcc catcgtcaaa aggcttagaa
    17821 acatcaatct tatccaataa aataacatga tgatgatcgt catgtggata catcaaggcc
    17881 ttaccctctg aagtatccaa taattgaatc ttgtctaatg gcaagcctgt atttttggcg
    17941 atataagctt tttttacggc aataatatct tcagctgatt gattagtgtc tagcggtaat
    18001 ttatcagctg ctgctacagg atttgcggtt tctgatgctt ttgtaattgg tttatcagcc
    18061 atcacctcag tgctgtcaga taactgttga ttagctgtat ctgcagtatc tttatcctca
    18121 cctaacctcg gttggactac agtgtgatta tccactgctg gtgattcatc agcaaatgct
    18181 actgacgagt tagttgacat cgctaaacca gcagccatta aagcagctgg gataagtaaa
    18241 gagtatcggg taacttgatt ctttttcatt aataactcct tataactatt attcatttta
    18301 attaattaac cagttaacta tatcaatcta tcaaaaaaaa tatagtatgt caacctctta
    18361 aagtgattta atcagaacaa acgtatgaag aaaatcattt ggtgaaaaag aagcttattt
    18421 tagctgaaat agatccatta taaaagaggt gtcgtgaagt aactcaatat tcacctattt
    18481 ttgtcgcaag tattctaata ggaatagaaa aagggcagtt gcttgcaaca actacccaat
    18541 gtaaaaccgt taaagacggt gacagaaaat aactgttaac tgaactacct caaaagttaa
    18601 accaaagatc taaccgttgg atgttggttt gtagagcggt tattttttta ttgttatgtt
    18661 tacaacgact aagctcatca gtgtaaggga aagggacttc catattaaga agtatatata
    18721 catcctagat gagacgtgta atgaatgggt tgaacaaata gttgcttaat tttgggataa
    18781 gggttataat aaaaatagaa aaagggcagt tgcttgcaac aactacccaa tgcagaaccg
    18841 tttgagacgg tggctggttt tatagttaaa agataaccgt taactcgcca aagttaagga
    18901 cggttatttt ttattgtcat ctttgaagat ttgatagcac aagctgataa gcgcaatagt
    18961 aaagctacta aagcctaaaa ggatttatac cacttcaaaa gctgtcaatg ctttgactca
    19021 tcctttctgt tagattttga tgaactgccc ataggcctca cctacctttc agaaataaga
    19081 gccaccgtct taacctttct gctttatcat tatagcatat tgttattaag gttgactatt
    19141 cagactcgtc taaagaagtg taatagttgc ttaattttgg gataagggtt ataatgaaaa
    19201 tagaaaaagg tagttgctcg acacaactac ccatgcagaa ccgtttaaga cggtggcatg
    19261 ttttatgtta ttaaaaaata accgttaact cgccaaagtt aaagacggtt attttttatt
    19321 gtcatctttg aagatttgat agcacaagct gataagcgca atagtaaagc tactaaagcc
    19381 taaaaggatt tgtaccactt caaaagctgt caatgctttg gctcctcctt tctgttagat
    19441 tgtgatgaac tgcccatagg cctcacctac ctttcagaaa taagagccac cgtcttaact
    19501 tttctgcctt tttattatag cataccctat ctctgattga ctagcttaag aaggagggga
    19561 tgtgatttgg atacaaattt ttgttaactt ttttaaagtc tccaaatgat ttaaaaaaat
    19621 gatattaatg ctctaagtaa gaatattaat aatatggttt taccacttat tgtatgaggt
    19681 atcatttcta aagagttatt tttcagacag aaggcttgtt aaagcaaaca gaagcaatac
    19741 taaaggcatt agatgataat caaggccttt ttcatgtctt aaaatgagta tactagctgt
    19801 cgtg
//
LOCUS       DARYNN010000039        19007 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.039, whole genome shotgun sequence.
ACCESSION   DARYNN010000039 DARYNN010000000
VERSION     DARYNN010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19007)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19007)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19007
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.039"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            71..1321
                     /locus_tag="TVB59_001447"
     CDS             71..1321
                     /locus_tag="TVB59_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEL1010331.1"
                     /translation="MKELKCPHCHTLFTVNESDYSQILAQVRGQEFDKELAQRLESEM
                     KLQEARANNRFQEVLTKKEQAIQSLTNRLERIEQEQAYLRQQELAQKDKELLELHNQL
                     DKLELEQQSRLQSALTVVEKERDHLKNQLVLQEKESELSLASVRSDYEVQLKAVNEQV
                     EFYKNFKAQQSTKAIGESLELYAETEFNKVRSYAFPNASFTKDNQVSHRGSKGDYIYR
                     ELDNNGVEILSIMFEMKNEVDTTKTKHKNSDFFKELDKDRREKNCEYAVLVTMLEADN
                     DYYNAGIVDVSHDYDKMYVVRPQLFIHLIGLLRNAALNSLKYKQELALVREQHIDITH
                     FEEDLEHFKHAFAKNYQSASNNFKKAVDEIDKSIKRMEEVKRFLTTSENQLRLANNKL
                     DDVSVKKLTRNNPTMRDKFQAIKP"
     gene            1430..2311
                     /gene="truB"
                     /locus_tag="TVB59_001448"
     CDS             1430..2311
                     /gene="truB"
                     /locus_tag="TVB59_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002271102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEL1010332.1"
                     /translation="MINGIINLKKEAGMTSHDAVFKLRKLLQEKKIGHGGTLDPDVVG
                     VLPIAVGKATRVIEYMTEAGKTYEGEVTLGYSTTTEDASGEIVDQTVVPLSLTEAMVD
                     EAMTQFIGQMTQIPPMYSAVKVNGRKLYDYARAGEAVERPKRQVTIDQFERTSPLTFA
                     GGLCRFSFRVSCSKGTYIRTLAVDLGRMLGYASHMSWLVRTASSGLSLDQSYTLSEIA
                     ELLDKKDMSFLLPIEYGVSDLARVVVNDWELRELSFGRKIALSCEENLLAAFYQDSLI
                     AILEKQEGLYKPRKVFI"
     gene            2325..3257
                     /locus_tag="TVB59_001449"
     CDS             2325..3257
                     /locus_tag="TVB59_001449"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEL1010333.1"
                     /translation="MDIQHIKSYQEIDESADTVLVLGYFDGLHRGHKALFDKAKEISR
                     QESLKIVTLTFHESPQLAFTRFSPDFLRHITYPEKRYEKFAEYGVDKLYLLDFTTSFS
                     KLSSDDFIDHYIGRLRVRHIVVGFDYHFGCDHADSHYLAKRIKGTVYSISEVKEDQIK
                     ISSTRIRSLITAGDVAKANQLLGYELSTRGMVVHGDARGRTIGFPTANLAPIDRTYLP
                     ADGVYVTDVLVRGKRYRSMTSIGKNITFGGKELRLEANIFDFNEDIYGETLEIIWLDR
                     IREMNKFSDVSTFISQLKQDKEAAINWKKDSQGY"
     gene            3300..3704
                     /locus_tag="TVB59_001450"
     CDS             3300..3704
                     /locus_tag="TVB59_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEL1010334.1"
                     /translation="MITLFLSPSCTSCRKARAWLTKHDVDFQEHNIITSPLSREELLA
                     ILSFTENGTEDIISTRSKVFQKLDIDIDELSIMDLIDLIAKNPSLLRRPIIMDSKRMQ
                     IGFNEDEIRAFLPRDYRKQELRQATIKAEIEG"
     gene            3706..3984
                     /locus_tag="TVB59_001451"
     CDS             3706..3984
                     /locus_tag="TVB59_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEL1010335.1"
                     /translation="MSDHYHYPLDVSWSTEEITSVLHFLNQVELAYEAKVGAEELLKS
                     YAAYKEIVRSKSQEKQIDREFQQASGYSTYQAVKKAREIEKGFFSLGR"
     gene            3974..4750
                     /locus_tag="TVB59_001452"
     CDS             3974..4750
                     /locus_tag="TVB59_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEL1010336.1"
                     /translation="MEDKYAFAKTIIKEAGLLIKDRMKDSLAIEIKTQHDDLVTNVDQ
                     ETQDFLIAKIKQAYPSDHMIAEEGGICHAITDGKVWVLDPIDGTVNFIVQKANFAIMM
                     AYYENGVGKFSLIYDVMADQLFSGGGDFAVTLNDQVLASYQDKPLDRSLIGCNAGMLS
                     RNDYNLHQLIDQTLGVRVYGGAGICMTKVLRQQLMAYFSYIQPWDYAAAAIMGESLGY
                     VLLTLEGKQPDFQSRQKVMFVPKSKLATIQSLLKTNENTQ"
     gene            4767..6074
                     /locus_tag="TVB59_001453"
     CDS             4767..6074
                     /locus_tag="TVB59_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEL1010337.1"
                     /translation="MQLPNDFIEKYQQLLGSEAKAFFESFDQPAISAYRINPLKHQSV
                     CLDPPIPDTPWGYYGRVSGKSPNHVSGVVYSQEPAAQMVAQVASPAKGTRVLDLAAAP
                     GGKSTQLLAYLENTGLLVSNEISTKRSKALVENIERFGARNVIVTNESADRLAAVFPE
                     YFDTIVFDGPCSGEGMFRKDPNAVSYWHKDYPAACASLQRSILAEAIPMLKPGGQLIY
                     STCTWSPEENEEVVRWLLESYDFLELEHIPKINGMAEGIGMPQAARMYPHRFKGEGQF
                     VAKLKDTRSTISSSSYKSPRSNLTQEQLRLWQDFEKNHLNITLSGLLQVFGDRLYLLP
                     DGLPCLRSLKIARNGLELGTFKKKRFEPSYALGLALRPEEVSLSVEINEEDFVTYASG
                     NTITLPESYATDWYQLVINGNGLGFAKIVGRTLKNSFPKGLRF"
     gene            6212..7078
                     /locus_tag="TVB59_001454"
     CDS             6212..7078
                     /locus_tag="TVB59_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HEL1010338.1"
                     /translation="MKSKKKFFLLSLLALSAFFLSACSSWIDKGESITAVGSTALQPL
                     VEAAADEFGSNNLGKSVNVQGGGSGTGLSQVQSGAVQVGNSDVFAEEKDGIDAAKLVD
                     HQVAVAGLAVIANPKVKVSNLTSKQLQKIFSGEYTNWKQVGGQDLAISVINRAASSGS
                     RATFDSVIMKGVTAKQSQEQDSNGMVKSIVSQTPGAISYLSFAYVDSSVKSLRLNGFK
                     ANAKNVATNDWPIWSYEHMYTKGKPDGLTKEFLDYVLSDEVQKTIVTHMGYIAITDMK
                     VVKSYDGKVTDK"
     gene            7089..8024
                     /gene="pstC"
                     /locus_tag="TVB59_001455"
     CDS             7089..8024
                     /gene="pstC"
                     /locus_tag="TVB59_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEL1010339.1"
                     /translation="MKNQELAKQLASPSKNSRLEAFGRTITFFCLALIVFIVAMILLF
                     VAQKGLSTFFVNKVNLFDFLFGTEWQPSVKNAAGVPYLGALPMIAGSFLVTILSALVA
                     TPFAIGAAVFMTEISPKYGAKLLQPAVELLVGIPSVVYGFIGLQVVVPFIRSIFGGTG
                     FGILSGVCVLFVMILPTVTFMTTDSLRAVPRHYREASMAMGATRWQTIWRVVLNAARP
                     GIFTAVIFGMARAFGEALAIQMVVGNSAVMPASLTTPAATLTSVLTMGIGNTVMGTVQ
                     NNVLWSLALVLLLMSLAFNSLVKLITKERKRNYER"
     gene            8014..8901
                     /gene="pstA"
                     /locus_tag="TVB59_001456"
     CDS             8014..8901
                     /gene="pstA"
                     /locus_tag="TVB59_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEL1010340.1"
                     /translation="MNAKKVDKVATGSLYTIAGIIVAILASLILFILVRGLPHISWSF
                     LTGKSSSYEAGGGIGIQLYNSFFLLVVTLIISIPLSTGAGIYLAEYAKKGPVTNVIRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLLHVH
                     HTQREAGLALGLSRWETVFHVVIPEALPSIVTGIVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNPLSVTSPISIFRQSETLAVHIWKVNSEGTIPDATLVSAGSAAVLLIFILIF
                     NLSARFIGKRIHAKMTAAK"
     gene            8918..9721
                     /gene="pstB"
                     /locus_tag="TVB59_001457"
     CDS             8918..9721
                     /gene="pstB"
                     /locus_tag="TVB59_001457"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEL1010341.1"
                     /translation="MTEYNWNERHIITFPEETIALATKDLHVYYGSKEAIKGIDMQFE
                     KNKITALIGPSGCGKSTYLRSLNRMNDTIDIARVTGEILYQGIDVNRKDMNVYEIRKH
                     LGMVFQRPNPFAKSIYKNITFAHERAGVRDKRVLDEIVETSLKQAALWDQVKDDLHKS
                     AFTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKDYTIIIV
                     THNMQQAARASDYTAFFYLGDLIEYDKTRNIFQNATCQSTNDYVSGHFG"
     gene            9735..10493
                     /gene="pstB"
                     /locus_tag="TVB59_001458"
     CDS             9735..10493
                     /gene="pstB"
                     /locus_tag="TVB59_001458"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEL1010342.1"
                     /translation="MAEPILQIRDLSVYYNKKKTLKDVSLDFYPNEITALIGPSGSGK
                     STLLRSINRMNDLNPEVTITGSIVYNGHNIYSPRTDTVDLRKEIGMVFQQPNPFPMSI
                     YENVVYGLRLKGIRDKAVLDHAVESSLKGASIWSEVKDRLHDSAVGLSGGQQQRVCIA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLFSLKKDYTMVIVTRSMQQASRLSDRTG
                     FFLEGDLLEFGPTKAMFMNPKRKETEDYISGKFG"
     gene            10564..11217
                     /gene="phoU"
                     /locus_tag="TVB59_001459"
     CDS             10564..11217
                     /gene="phoU"
                     /locus_tag="TVB59_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEL1010343.1"
                     /translation="MLRTKFEEELDKLHNQFYSMGTEVLSQINKTVRAFVSHDRELAK
                     EVIEEDDTINGFETKLEKKSLEIIALQQPVSNDLRTVITVLKASSDIERMGDHAASIA
                     KATIRMKGEERIPIVEEHINLMGKAVKQMVEEALNAYINADDAKAYEIAASDEIIDNY
                     FREIQSLAVEEIRKTPDAVFAGKEYFQVLMYLERIGDYARNICEWIVYLKTGKIIEL"
     gene            11451..13988
                     /locus_tag="TVB59_001460"
     CDS             11451..13988
                     /locus_tag="TVB59_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEL1010344.1"
                     /translation="MKKVEHLIEKFIPENYNIFLDINRSTKTFTGNVAINGEALDNQV
                     SFHQKDLAINAILLDNEAVSYHVDDDNELVRVELPETGMMTLVIEFSGNITDNMTGIY
                     PSYYTKDGEKQEVISTQFESHFAREAFPCIDEPEAKATFDLSLTFDQAEGEIALSNMP
                     EVNAERRKETGLWTFETTPRMSSYLLAFALGDLHGKTTKSKNGTTVGVYATKAHPLTS
                     LDFSLDIAVRVIDFYEDYFGVRYPIPQSLNIALPDFSSGAMENWGLITYREIYLLVDG
                     NSTARSRQNVALVVAHEIAHQWFGNLVTMKWWDDLWLNESFANMMEYVAINAIEPSWR
                     IFEDFQTTGVPLALKRDATDGVQSVHVAVNHPDEINTLFDPAIVYAKGSRLMHMLRRW
                     IGDKDFAAGLRLYFEKHQYRNTVGRDLWQALSEASGKDVAAFMDAWLEQPGYPVLTAR
                     VDNDQLILSQKQFFIGEASDQKRLWPIPLNANWKGLPDVLTEESIVISGFSQLAAQNK
                     GTLRFNTENTAHYITDYQGQLFHSLVDDLKHLDNTSALQVIQERRLLADSGLISYAEL
                     VDLIAQLDDKKSYMVAAAVQQVIRGLEQFIDEGTSAEQSFNRLISSIFQEDFRQLGFE
                     KRANESDEDEMVRQIALHHLLVGGNRDVIKQAKTIFEAYANRIEAIPAAIRRSVLVSQ
                     IKYFEIADLVDAYFDAYVATKDNNLRADLSAALATTANPSTLKRIQYSLKDKDIIKPQ
                     DLAAWYSFLLDQASAQESIWRWARENWKWIKASLGGDMSFDKFIIYPANHFKTAERLA
                     EYKAFFEPQLDDMAISRNISMGINEISARVALIDSEKEAIANALSQY"
     gene            14407..15081
                     /locus_tag="TVB59_001461"
     CDS             14407..15081
                     /locus_tag="TVB59_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1010345.1"
                     /translation="MIKLLLVEDDLSLSNSIFDFLDDFADVTQVFDGDEGLYEAESGI
                     YDLILLDLMLPEKDGFQVLKALREKDIKIPVLIMTAKESIDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRVGKFNDKSLKFGNLTVDTTRKEVQVNGQAIELLGKELDLLIY
                     ILQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTDFVNHLQTLRSVGY
                     ILKANE"
     gene            15074..16384
                     /locus_tag="TVB59_001462"
     CDS             15074..16384
                     /locus_tag="TVB59_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEL1010346.1"
                     /translation="MNKLKKGLLSDNYTHFFHFFAIFTGIFVVMTIIILQIMRFSVYS
                     TVDSSLISVSQNASNYANRTMARISSFYFDAENNLIQALPELEASKSLGSSTTNMDII
                     LFSANGTILNSFDAFSNYQSFRLDKSQLNNIVTTQLMNFYGQKEKYHTLTVKVHIKNY
                     PAVAYMMAVVNVQQLDTANERYEQIIIMVMIVFWLISILASIYLAKWSRKPIMESYAK
                     QKMFVENASHELRTPLAVLQNRLESLFRKPNETILDNSEHIASSLDEVRNMRILTTNL
                     LNLARSDDGIKPQLVDVDAAFFDTVFENYQLVAEESGKQFISVNQINRPLKTDKALLK
                     QLMTILFDNAIKYTDHNGVVEVKVRTTDKHLLISVIDNGPGIKDDDKKKIFDRFYRVD
                     KARARQKGGFGLGLALAQQIVTSLKGTITVSDNKPTGAIFEVKL"
     gene            16769..17188
                     /locus_tag="TVB59_001463"
     CDS             16769..17188
                     /locus_tag="TVB59_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010347.1"
                     /translation="MIVYLKQHKNYWKLVSIAALIIILGGILTMNWLNGEELKKKKYR
                     QEQDRVVKYIGEHIELCNGQPITKIEFIEFQLETATTGTWSITTIVNEKYLIHFSEDR
                     LGEEIRTSYYSPKEFKQYSEKMRNNMTNVETIYYEEK"
     gene            17185..18378
                     /locus_tag="TVB59_001464"
     CDS             17185..18378
                     /locus_tag="TVB59_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010348.1"
                     /translation="MMIDRDYKNISEDVYKVDSGKERDPIQEGYPVANGKYRVLEAED
                     NPDNGMQAMAVVPIKDGKEDRSHIVIAYAGTNSSDIRDIDTDIQSVVFGDDQYLCTHE
                     EPDSFKVVKSQLSTAKAFSDYIRTSYPNAAISYTGHSLGGYLALITAAHAKQPATVFN
                     APSSVNNLSKEAIDFVKANKGLYHSYRINNDYIGNLGTYFGDDELGISRWVDGKAGIG
                     RHSLAAYRFNSKGQVIDRKGRPAAAQAPALATLSSKLTEYRLLKKKYVASNGISSSEE
                     FYLDQFQARAVAQALEQTTQLAQEEIIARRKEAVAEAEALHQKTRDMPFFVSELSWAE
                     LEEAYAQAGVTYDSLVGQTKRHFDDKVTQARGLATKFKTVKEQLEEGVERTAAIDQKL
                     GCDFS"
     gene            18375..18767
                     /locus_tag="TVB59_001465"
     CDS             18375..18767
                     /locus_tag="TVB59_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010349.1"
                     /translation="MTALEKIRTAIRQKEEELEEQQEHYHQERLQMAAAHDELRGNYN
                     QLQQLYASSYQAVSSYLRHYDASLITDQYTVLTRLIDDYQHRTEQCYHEQGRKMSQQE
                     EAIDHHYRSQRQAIEKDITALRRQWREG"
     gene            18787..>19007
                     /locus_tag="TVB59_001466"
     CDS             18787..>19007
                     /locus_tag="TVB59_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010350.1"
                     /translation="MIAIEMILTGQEPIRTLKKELDRRLVQSICAPLTLGRLHALQRR
                     YDSEVSRIATDTADHIQTIVNQLDSSIRG"
BASE COUNT         5704 a         3549 c         4309 g         5445 t
ORIGIN      
        1 tctggaaaaa tcattttcta ggcttttttt gctataatgg cagtgagata attgcaagaa
       61 tggagaaatc atgaaagaac taaaatgtcc tcattgccat accttattta cggtcaatga
      121 gtctgactat agtcagattt tagcacaggt acgaggtcaa gagtttgaca aggagttggc
      181 acagcgctta gaaagtgaga tgaagctgca agaagcaagg gccaataacc gcttccaaga
      241 ggtgcttact aaaaaggagc aggctattca aagcctgacc aaccgcttgg agcgtattga
      301 gcaggaacag gcctatttga ggcaacagga gctagcccaa aaggataaag agctcctaga
      361 gcttcacaat cagctagata agctagagct tgagcagcaa tcaaggctcc agtctgccct
      421 tacagttgtt gaaaaggaac gtgatcacct aaaaaatcag ctcgtgctgc aggaaaaaga
      481 aagcgaactt tctctagcct ctgtgcgcag tgattatgag gtgcagttaa aggctgtcaa
      541 tgagcaggtt gagttttaca agaattttaa agcgcagcag tcaactaaag ctattggaga
      601 gagcttagag ctgtatgccg aaaccgagtt taacaaggtt cgcagctatg cctttccaaa
      661 tgccagtttt accaaggaca atcaagtgtc tcatcgaggc tcaaagggtg attatattta
      721 ccgagagcta gacaataatg gtgttgaaat tctctcaatc atgtttgaaa tgaaaaatga
      781 ggttgacacg accaagacca agcataaaaa tagtgatttc tttaaggaat tagataagga
      841 tcgccgggaa aagaattgtg aatatgctgt tcttgttacc atgcttgaag cagacaatga
      901 ttattacaat gcaggaattg ttgatgtcag tcatgactat gacaaaatgt atgtggttcg
      961 gcctcagctc tttattcatc tcatcggatt gctgcgtaac gctgctctta atagcttaaa
     1021 atataagcaa gaactggcgc ttgtcaggga gcagcacatt gatattacac attttgagga
     1081 ggacctagag cattttaagc atgcttttgc taaaaactac cagtctgcaa gcaataactt
     1141 taaaaaagcc gttgatgaaa ttgataagtc catcaagcgt atggaggagg tcaagcgctt
     1201 tctaacaact agcgaaaatc agctgcgttt agccaataac aagctagatg atgtctctgt
     1261 caaaaaacta accagaaata atccaaccat gcgcgataag tttcaagcaa tcaagcccta
     1321 ggattatctc agtcaggctt attgatagag gctttgttgc ttgtcaaaag ccttgtgaaa
     1381 tggttataat agataggcta atgatcaaaa caataaacga aagtaacaca tgataaacgg
     1441 aataatcaat ttaaaaaaag aagcaggcat gacatcacat gacgctgttt ttaagcttag
     1501 aaagctatta caagaaaaaa agattgggca tggagggacg cttgatcctg acgtggtcgg
     1561 tgttttgcct atagcagtgg ggaaggcaac gcgagttatt gaatacatga cagaagcagg
     1621 taaaacctat gagggagagg ttactcttgg ctattcaacg acaacagagg atgctagtgg
     1681 agagattgtt gaccaaacag tagtgccctt gagtttgact gaagcgatgg ttgatgaggc
     1741 aatgacacaa tttattggtc aaatgactca gattccaccg atgtattctg cggttaaggt
     1801 taatgggcgc aagctttatg attatgcacg agctggtgaa gcagtcgagc gccctaaaag
     1861 acaggtaacg attgaccagt ttgagcggac aagtcccttg acctttgcag gtggtctttg
     1921 ccgatttagc tttagggtga gctgtagcaa ggggacttat attaggacct tggcggttga
     1981 tctaggaaga atgcttggct atgcaagtca tatgtcttgg ctggttcgga cagcttcttc
     2041 gggtttaagt ttggatcagt cctatacctt gtcagagatt gctgagctgc tggataaaaa
     2101 ggacatgagc tttttattgc ctattgaata tggtgttagt gatttagcca gagtagtcgt
     2161 taatgactgg gagctgagag agctttcctt tggtagaaaa atcgctctat catgtgagga
     2221 aaatctgtta gcggcttttt atcaggacag cttgatcgct attttagaaa agcaagaagg
     2281 gctttacaag ccaagaaagg tttttattta gagaagattg atatatggat atacaacaca
     2341 ttaaaagcta tcaggagatt gatgaatcag ctgataccgt tttagtctta ggctactttg
     2401 atggtctgca ccgaggtcac aaggctctat ttgataaggc aaaggaaata tcacgtcagg
     2461 aaagcctaaa aatagtcacc ttgaccttcc atgagtcccc tcagctggcc tttacacgct
     2521 tttctcctga ttttttacga cacattacct atccagaaaa aaggtatgaa aaatttgctg
     2581 agtatggtgt tgataagctt tatttgcttg attttaccac gtcattttca aaactatcct
     2641 ctgatgattt cattgaccac tatattgggc gtttaagggt aaggcatatc gttgtaggct
     2701 ttgattatca ctttgggtgt gatcacgcag atagtcatta cttagctaaa cggataaaag
     2761 gaaccgttta tagcatttca gaggtcaaag aagaccagat caaaatctca tcaacacgta
     2821 tcagaagtct gattacagca ggagatgtcg ctaaggctaa tcagctgctt ggctatgagc
     2881 tttcaacaag aggaatggtt gtgcatggtg atgcgcgtgg gcgaaccatt ggttttccga
     2941 ctgccaatct tgcacctatt gataggacct atctgccagc tgatggtgtt tacgtgacag
     3001 atgtgctggt tagaggaaag cgctatcggt ctatgacgag tatcggcaag aacattacct
     3061 ttggtggtaa agagctgcga ttagaggcaa atatttttga ttttaatgag gacatttatg
     3121 gagaaactct tgaaattatt tggctagata ggattcgtga gatgaataaa tttagtgatg
     3181 ttagcacctt tatcagccaa ctaaagcagg ataaagaagc tgccataaat tggaaaaaag
     3241 atagccaagg ctattaaatt tttgtataat aaggtaagca caattaacag aggaaaagta
     3301 tgattacctt atttctatca ccaagctgta ctagctgccg taaggccaga gcctggctca
     3361 ccaagcatga cgttgacttt caagagcata atattattac cagcccactt agtcgtgagg
     3421 agctgttagc gatcctatcc tttactgaaa atggaacaga ggatattatt tcaacacgat
     3481 caaaggtttt tcaaaaattg gatattgata ttgatgagct gtctatcatg gatttgattg
     3541 atttgatcgc aaagaaccct agccttcttc gtaggccaat cattatggat agtaagcgca
     3601 tgcaaattgg ctttaatgaa gatgagatta gggcattttt gccaagggat tatcgtaagc
     3661 aagagctgcg ccaagcaacc ataaaggcag aaatcgaggg ataacatgtc agatcattat
     3721 cattacccac ttgatgtaag ctggagcact gaagagataa catcagtgct tcatttttta
     3781 aatcaggtag agttagccta tgaggctaag gtaggagcag aggagctact caaaagctat
     3841 gctgcctaca aggagattgt aagaagcaaa tcacaggaaa agcagattga ccgcgaattc
     3901 caacaagcca gtggctattc aacctatcaa gctgtcaaaa aagccagaga aattgagaaa
     3961 ggattctttt cccttggaag ataaatacgc atttgctaaa acgatcatca aagaggctgg
     4021 ccttctgatt aaggatagaa tgaaagatag cttagccatt gaaatcaaga cgcagcatga
     4081 tgatttagtg accaatgtag atcaagagac gcaggatttc ttaattgcta aaatcaaaca
     4141 ggcctatcct agtgaccata tgattgctga ggagggcggt atctgtcatg ctattacaga
     4201 tggcaaggtt tgggtgctgg atcctattga tggtacggtg aattttattg tacagaaagc
     4261 caattttgcg atcatgatgg cttattatga gaatggcgtc ggaaaattta gtctcattta
     4321 tgatgtcatg gcagatcagc ttttttcagg tggaggagat tttgctgtta ctttaaatga
     4381 tcaagtccta gcatcttatc aggataagcc gcttgatcgt agcttaattg gctgcaatgc
     4441 aggtatgctt tcaaggaacg attacaacct gcaccagttg attgatcaaa ccctaggagt
     4501 gagggtttat ggcggtgcag gcatttgcat gactaaggtg ttaaggcagc agctaatggc
     4561 ttatttctct tatattcaac cttgggatta tgcagcggca gccattatgg gcgaaagcct
     4621 tggctatgtc ctgttgacct tggagggaaa gcagccagac tttcagtcta gacagaaggt
     4681 gatgtttgtt cccaagtcta aactagccac cattcaatct ctgctgaaaa caaacgagaa
     4741 tacccaataa gattaaaatg aaaagcatgc aattaccaaa cgattttatt gaaaaatacc
     4801 aacagctgct aggttcagaa gcaaaagctt tttttgagag ctttgatcag cctgccatca
     4861 gtgcctacag gataaatccc ttaaagcacc aatcggtctg ccttgatcct cctattcctg
     4921 atacaccatg gggttactac ggcagggtat caggaaagtc tcctaaccac gtgtcaggtg
     4981 tggtgtattc ccaagagcct gctgctcaaa tggttgctca ggtggcctca cctgccaagg
     5041 gaactagagt gttggatttg gcagcagcgc caggtggcaa gtcaactcag ttacttgcct
     5101 atctagagaa tacaggactt ttagtgagta atgagatttc gaccaaacgc agcaaggcct
     5161 tagttgaaaa tatagagcgc tttggtgcta gaaatgttat tgtgacaaat gagtcagctg
     5221 acagactggc tgctgttttt ccagaatatt ttgacactat tgtctttgac gggccttgct
     5281 ctggtgaggg catgtttcgc aaggatccaa atgctgttag ctattggcac aaggattacc
     5341 cagcagcatg tgctagcctg caaagatcca ttttagcaga ggcgatacct atgctaaagc
     5401 caggtggtca gctgatttat tcgacctgca cctggtcgcc tgaagaaaat gaagaggttg
     5461 ttcgctggct actagaaagt tatgattttc ttgagctgga gcatatccct aagatcaatg
     5521 gtatggcaga ggggatcggt atgccacagg cagctagaat gtaccctcat cgctttaaag
     5581 gagagggaca gtttgttgct aagttaaagg atactagatc aacgatttcc tcttcaagct
     5641 acaaatctcc aaggtctaac ctcactcaag agcagctgag gctgtggcag gattttgaaa
     5701 aaaatcattt gaacataacc ttgtctggcc tattacaggt ctttggtgat cgtttgtact
     5761 tgttaccaga tggcttaccc tgtcttcgat cgcttaaaat agcaagaaat ggtctggaat
     5821 taggcacttt taagaaaaaa cgctttgagc cttcctatgc tctgggcttg gcattaagac
     5881 ctgaagaggt cagcttatct gttgagatta acgaagagga ctttgtcaca tacgcctcag
     5941 gaaataccat taccttacca gaatcttatg ctacagattg gtatcagctg gtcattaacg
     6001 gaaatggtct gggctttgct aaaatagttg gtcgcaccct taaaaatagc ttccctaagg
     6061 gcttacgttt ttaaggaatg gcataccatt aaatttttat aaatttaaat aaaacttctt
     6121 ccaaagcatt gttagatatg ttaatataaa gaatatgctg aagcttaatt cttcgctata
     6181 aacctttatt tttatgaata ggaatagaat aatgaaatcg aaaaagaaat tctttttgtt
     6241 aagtctttta gccttgtcgg ctttcttttt gtcagcctgc tcaagctgga ttgataaggg
     6301 agaatccata acagcggtag gctcaacagc attacagccc ttagtagaag ccgcagctga
     6361 tgagtttgga agcaataacc tcggaaaatc tgttaatgtt caaggaggcg gctctggcac
     6421 tggcttatca caggtgcagt caggtgctgt tcaggtaggc aatagtgatg tctttgcaga
     6481 agaaaaggac gggattgatg ctgctaagct tgttgatcac caggttgccg tagcaggact
     6541 tgctgtcatt gccaatccta aggtcaaggt atctaatctc acaagcaagc agctacaaaa
     6601 gattttctca ggtgaatata ccaactggaa gcaggttggt ggacaggatc ttgctatttc
     6661 agtgattaat cgagcggcaa gctcaggctc acgtgctacc tttgatagtg tcatcatgaa
     6721 gggtgttact gctaagcaaa gtcaagagca ggattctaac ggtatggtta aatcaattgt
     6781 gtctcagaca ccgggggcca tttcttactt atcctttgcc tatgtggatt cgtctgtaaa
     6841 atcattacga ttgaatggct ttaaggccaa tgccaaaaat gtagcaacca atgattggcc
     6901 catctggtcc tatgagcata tgtataccaa aggcaagcca gacggcttaa ccaaggaatt
     6961 tttggattat gtgctatcag atgaggtcca aaaaaccatt gtgacacata tgggttatat
     7021 tgctatcact gatatgaagg tcgtcaaatc ctatgatgga aaagttacag ataaataatg
     7081 ggggaattat gaaaaatcag gaattagcta agcaattagc ctcaccatca aaaaattcac
     7141 gacttgaagc atttggtcgt acgattacct ttttttgcct cgccttaatt gtttttatcg
     7201 ttgcaatgat tttacttttt gtggctcaaa agggcttgtc tacctttttt gtaaacaagg
     7261 ttaatctttt tgatttccta tttggtacag agtggcagcc tagcgttaaa aatgctgccg
     7321 gtgttcctta tcttggagct cttccgatga ttgctggatc gtttttagtc acgattttat
     7381 cagccttggt ggcaacacca tttgccattg gggcagcagt atttatgact gaaatttcac
     7441 ccaagtacgg ggcaaaacta ttacagccag cagttgaatt gcttgtaggt atcccgtcag
     7501 ttgtttatgg ctttattggc ttgcaggttg ttgttccttt tattcgttct atttttggtg
     7561 gaacaggctt tggtatccta tcaggggtct gtgtcttgtt tgtcatgatt ttaccgacgg
     7621 ttacctttat gacaacagat agtctgcgcg ctgttcctcg tcattatcgt gaggcttcta
     7681 tggctatggg ggctacacgt tggcaaacca tttggcgagt ggttttaaat gcggctcgtc
     7741 ctggtatttt tactgctgtt atttttggta tggctagagc ctttggtgag gccttagcca
     7801 ttcaaatggt tgtgggaaat tcagcagtca tgccggcttc actaaccact ccagcggcta
     7861 cattgacctc tgtattgact atgggaattg gtaatacagt tatgggaact gttcaaaata
     7921 atgtgctatg gtcattagcc cttgtcttat tgctgatgag tctagctttt aattcccttg
     7981 tcaaattaat tacgaaagag agaaagagaa attatgaacg ctaaaaaggt tgataaagta
     8041 gcaactggta gcttgtatac tattgctgga attattgtag ctattttagc ttccctaatt
     8101 ctgtttattc ttgtgcgtgg cctacctcac atcagctggt cgtttttaac agggaaatca
     8161 tcgtcctatg aagctggtgg aggtattggg attcagcttt ataattcatt tttcttgctg
     8221 gtagtaacct tgattatttc cattccccta tcaacaggtg ctggcattta tttggccgaa
     8281 tacgctaaaa aaggacctgt gacaaatgtg attagaacct gtattgaaat cctatcctca
     8341 ttgccatctg ttgtggttgg attgtttggc taccttattt ttgttgtaca gtttgaatat
     8401 ggcttttcta ttatatcagg tgcccttgct ttgacggtat ttaatcttcc gcaaatgaca
     8461 agaaacgttg aggatagctt gctgcatgtg catcatactc aaagagaggc agggctagcc
     8521 cttgggcttt cacgctggga aacggttttt catgtggtta ttccagaggc cttgccaagt
     8581 attgtgacag gtattgtttt ggcttcaggt cgtatctttg gtgaagcagc tgctcttatc
     8641 tatactgcgg gtcagtctgc cccagcgctt gattggtcaa attggaaccc tttgagcgtg
     8701 acaagcccta tttcaatttt ccgtcaatct gaaaccctag ctgttcatat ttggaaggtc
     8761 aatagtgaag ggacaatccc tgatgcaaca cttgtttctg ctggtagtgc agcggtgttg
     8821 ttgattttta tccttatttt caatctatca gctcgcttta ttggcaagcg tattcatgct
     8881 aagatgacag cagcaaaata agacattgga gagattcatg acagaatata attggaacga
     8941 acgtcatatc attacatttc cagaagaaac gattgcccta gctactaagg atctgcatgt
     9001 ttattatggt agcaaggagg caatcaaggg gattgatatg caattcgaaa aaaataaaat
     9061 tacagcccta attggaccct caggctgtgg caagtcaacc tatctgcgca gcctcaatcg
     9121 catgaatgac accattgata ttgctagagt aacaggtgaa attttgtatc aaggcattga
     9181 tgtcaatcga aaggacatga atgtgtatga aatccgtaag cacctaggaa tggtctttca
     9241 aaggccaaat ccatttgcca agtctattta taaaaacatc acctttgctc atgaaagagc
     9301 aggagtgaga gataaaaggg ttttagatga gattgtcgaa acctccctca agcaggctgc
     9361 actatgggat caggtcaagg acgatcttca taaatcagcc tttacccttt caggaggtca
     9421 gcagcagcgc ttgtgtattg ctagggctat ttcggttaag ccggatatct tgttgatgga
     9481 cgaaccagct tcagcccttg atcctattgc aaccatgcag ctagaagaaa ccatgtttga
     9541 gttgaagaag gattacacca ttattatcgt tactcataac atgcagcagg ccgctagagc
     9601 aagtgattac actgctttct tctatttggg tgacttaatt gaatacgata aaacgcgtaa
     9661 cattttccaa aacgctacct gtcagtccac aaatgattac gtctcagggc actttggtta
     9721 gaaagaagga tatgatggca gaacctattt tacaaatcag agatctttct gtttactata
     9781 ataaaaagaa aaccttaaag gacgtgtcct tagattttta cccaaatgaa atcacagcac
     9841 tcattggccc ttcagggtct gggaaatcaa cacttttgcg ttccatcaat cgcatgaatg
     9901 acctgaatcc agaggtaacc attacggggt caatcgttta taatggacat aacatttaca
     9961 gtccaagaac agacactgtt gatttgcgaa aagaaattgg tatggtcttt cagcagccca
    10021 atccctttcc aatgtctatc tatgaaaacg ttgtctatgg cttgcgccta aagggcatta
    10081 gagataaggc tgttttagat cacgctgttg aatcctctct caaaggagcc tccatctgga
    10141 gtgaggtcaa ggataggctt catgattcag ctgttggact atcaggaggt caacagcagc
    10201 gtgtctgcat agcaagggtt ctggcaacca gccctaaaat cattttgtta gatgagccaa
    10261 catcggcttt agatcccatt tcagccggca aaatcgaaga gaccctgttc tcactaaaaa
    10321 aggattatac gatggttatc gttacccgct ccatgcagca ggcctcgcgc ttgtcagacc
    10381 ggacaggctt cttcttagag ggagaccttc ttgagtttgg tcctactaag gcaatgttta
    10441 tgaaccctaa gaggaaggaa acagaagatt atatttcggg taaatttggc taagggatct
    10501 tgtttgtagt ctaggtatcc gctctgttta ggataataaa tgaatcaata gaaagaaaaa
    10561 atgatgttaa gaactaaatt tgaagaagaa ttagacaagc tacacaatca gttttactct
    10621 atgggaacag aagtcttgtc tcaaatcaat aaaaccgttc gtgcctttgt cagtcatgac
    10681 cgcgaattgg ccaaagaggt gattgaggaa gacgatacca tcaatggatt tgaaacaaaa
    10741 ttagaaaaaa agtctcttga aattatcgcc ttacagcagc ctgtttcaaa cgatttgcga
    10801 acagttatta ctgttttgaa ggcctcaagt gatattgagc gtatgggaga tcacgctgcc
    10861 tctatcgcta aagcaaccat tcgcatgaaa ggagaagagc gtatcccgat tgttgaggag
    10921 catatcaact tgatggggaa ggcagtcaag cagatggttg aagaggcgct aaatgcttat
    10981 attaatgcag atgatgccaa ggcctatgaa attgctgctt cagacgaaat cattgataat
    11041 tatttccgcg aaatccaatc tctagctgtc gaagaaattc gcaagacacc agatgccgtc
    11101 tttgctggca aggaatactt ccaggttctc atgtatttag agcgtatcgg tgactatgct
    11161 cgtaatattt gtgaatggat tgtctattta aaaactggaa aaattattga attataagaa
    11221 agtatggtat aatgggggct gggtgaactt ctcagttcct cgttttatta tagcgattaa
    11281 aaggttttag aggctggagc ttcagctgag ctgactatca gctgtcaagc ttctagacaa
    11341 aatgaaagat aacaataagc tagtcgtcta agggactaga cggcaggatt gattatatta
    11401 agaatgtgac cttgtcccat cactaattta atgacatatt aaggagttgt atgaaaaaag
    11461 tagaacatct tattgaaaag tttattcctg aaaattataa tattttctta gacattaatc
    11521 gcagcacaaa aaccttcaca ggtaatgttg caatcaatgg tgaagcatta gataatcaag
    11581 tgtcatttca ccaaaaggac ttggcaatca atgccatttt acttgacaat gaagctgtta
    11641 gctatcatgt tgacgatgac aatgagcttg tgcgtgttga gctgccagag actggtatga
    11701 tgacgcttgt cattgaattt tcaggtaata ttactgacaa tatgactggt atttacccgt
    11761 cctattacac aaaagatggt gaaaaacagg aggttatttc aacgcagttt gaaagccatt
    11821 ttgcgcgtga ggcctttcca tgtattgacg agcctgaagc aaaggctacc tttgacttaa
    11881 gcttgacatt tgaccaagca gagggcgaga ttgctctatc aaatatgcct gaggtcaatg
    11941 ctgagcgccg caaggagacc ggtctttgga cctttgagac aactcctaga atgtcttctt
    12001 atctgctggc ctttgcctta ggagacttgc atggcaaaac aacaaaaagt aaaaacggga
    12061 caacagttgg tgtttatgca accaaggctc acccactgac ctcgctagat ttttcattgg
    12121 atattgctgt acgtgtcatt gatttttacg aagactactt tggggttcgc tatcctattc
    12181 cgcaatctct aaatattgct cttcctgatt tttcatctgg agcgatggaa aactggggct
    12241 tgattaccta tcgtgaaatt tacctgttgg ttgatggcaa ttcaacagcc cgcagcagac
    12301 aaaatgttgc tcttgttgtg gcacacgaga ttgcccatca atggtttggt aatcttgtaa
    12361 ccatgaaatg gtgggacgat ctttggctaa atgaaagctt tgccaatatg atggaatatg
    12421 tagccatcaa tgctattgag ccgtcatggc gtatttttga ggatttccaa acaacaggtg
    12481 tgccgctggc tcttaagcgt gatgcaacag acggtgttca atcagtccat gttgctgtta
    12541 atcacccaga tgagattaat accctgtttg atccagctat tgtctatgcc aaaggtagcc
    12601 gcttaatgca tatgcttcgt cgctggattg gcgataagga ttttgcggca ggtctgcgcc
    12661 tttactttga aaagcatcaa taccgtaata ctgtaggacg tgatttgtgg caggctcttt
    12721 cagaagcttc tggtaaagat gttgctgcgt ttatggacgc ttggctagag cagccaggct
    12781 atcctgtctt aacggccaga gttgacaatg atcagttgat tctcagccaa aagcagttct
    12841 ttattggtga ggcaagcgac caaaagagac tatggccaat tccactaaat gcgaactgga
    12901 aaggtcttcc tgacgtactg acagaggagt ccatcgttat ttcaggcttt agtcaattag
    12961 ccgcccaaaa taaaggaaca cttcgcttta atacagaaaa tacagcgcat tacattacag
    13021 attatcaggg acagctcttt catagcttag ttgatgattt gaagcatctt gacaacacct
    13081 ctgcccttca agtgattcaa gagcgccgct tgctggctga tagcggtctg atttcttatg
    13141 cagagctggt tgacttaatc gctcagctag atgacaaaaa atcctatatg gttgctgcag
    13201 ctgttcagca ggttattaga ggcttagagc agttcattga tgaaggaacc tcagcagagc
    13261 agtccttcaa tcgattgatt tcttctattt tccaagagga cttcaggcag cttggatttg
    13321 aaaagagggc aaatgaatct gatgaagatg aaatggttcg tcaaattgct ttacatcacc
    13381 tgttggttgg aggcaatcgt gatgtgatca agcaggccaa gactatcttt gaagcttatg
    13441 caaatcgtat cgaagccatt ccagcagcca ttcgccgctc ggtattggtg agtcagatca
    13501 agtattttga aatagctgac ttggttgatg cttattttga tgcttatgtt gcaaccaagg
    13561 acaacaatct tcgagctgat ttgagcgccg ccttagcaac aacagctaat ccatcaactc
    13621 ttaagcgcat tcagtacagc ttaaaggata aggatattat taagccacag gacttagcag
    13681 cttggtacag ctttttgctt gatcaggcct ctgcacaaga aagcatttgg cgttgggcta
    13741 gagaaaattg gaagtggatt aaggcttcac tgggtggtga tatgagcttt gacaagttta
    13801 ttatttaccc tgctaaccat tttaaaacag cagagcgttt agctgaatat aaggccttct
    13861 ttgagccaca gcttgatgat atggcgatta gtcgcaatat ttcgatgggg ataaatgaaa
    13921 tttcagctcg agttgccctc attgatagtg aaaaggaagc tatcgctaat gctttaagtc
    13981 agtactaatg atatcacaaa ggagctgggg accatcctca actcctttat tggtgtcaaa
    14041 gctactatct ttaagtaaca tttagatcaa agggtaattg ctgtagctta gtggcactgc
    14101 ctgtcagctt ttggcaaatg aggaggcttc aatcataagc agtggttaat cttagcgccg
    14161 taaattacta gttgatcaga gtcagagctt aggacggata ggtcatagag acaattcttt
    14221 gtctgtcagt tttataactt aagtaggtct ccagactaac tgtatgctta tgacctgtca
    14281 tgagcaatag tttagcaaag cttaagcttt ttgtgttatc gttagattag agaattcatt
    14341 tagtaaggta atccctaaag actacttgag cgaggctgtt agtctttaga gaattgaggt
    14401 atcataatga taaaactatt attagtagaa gacgatttaa gcttgtcaaa ttctatcttt
    14461 gattttttag atgactttgc tgatgtgacg caggtttttg atggtgacga aggactctat
    14521 gaggcagaaa gcggtattta tgatttgatt ctgttagatt tgatgctgcc tgaaaaggat
    14581 ggctttcaag tgttaaaagc cttacgtgaa aaagacatca aaattcccgt cttgatcatg
    14641 actgccaaag aaagcatcga tgacaaaggg catggctttg agcttggtgc tgatgactat
    14701 ttaaccaagc ccttttacct agaagaatta aaaatgcgga ttcaggcctt gcttaagcgc
    14761 gtaggaaagt ttaatgacaa gagccttaaa tttggcaacc tgactgtaga tactacccgt
    14821 aaagaggtac aggtcaatgg gcaggccata gagctattag gcaaggagct tgatttacta
    14881 atctatatcc ttcaaaatca aaatgttatt ttgccaaaat cacaaatttt tgatcgtatc
    14941 tggggctttg atagtgatac cactatctct gttgtagagg tctatgtctc taaaattcgt
    15001 aagaagctta aggggacaga ctttgttaat catcttcaaa ccttgagaag tgtaggatat
    15061 atcttaaaag ctaatgaata aactaaaaaa aggattattg tccgataatt atacgcattt
    15121 ttttcatttc tttgctattt ttacaggcat ttttgttgtc atgaccatca ttattttaca
    15181 aatcatgagg tttagtgtct attccacagt agacagcagt ctcatttcgg tcagtcaaaa
    15241 tgccagcaac tatgctaata ggaccatggc gagaatatct tccttttatt ttgatgcaga
    15301 aaataacctt attcaggctc ttcctgaact ggaagcgtca aaatcacttg gctcctccac
    15361 cactaatatg gatattattt tatttagtgc taatgggacg atattgaact cctttgacgc
    15421 tttctctaat taccaaagct ttcgtttaga caaaagccag ctcaataaca ttgtcaccac
    15481 acagctgatg aatttttatg ggcaaaagga gaaataccat accctaaccg ttaaggttca
    15541 cattaaaaac tatccagcag tggcttatat gatggcagtg gttaatgttc agcagctgga
    15601 tactgctaat gagcgctatg aacagattat tatcatggtt atgattgtct tttggttaat
    15661 ttcgattttg gccagtattt atttggctaa gtggagcaga aagccaatta tggagagcta
    15721 tgccaagcaa aaaatgtttg tagaaaatgc cagtcatgag cttaggactc ctttagcggt
    15781 gctgcaaaat cgtttggaat cgctgtttag aaagcctaac gaaaccattt tagacaatag
    15841 cgagcatatt gcgtcaagcc tagatgaggt tcgtaatatg agaatattaa caactaatct
    15901 gttaaattta gccagaagtg atgatgggat caagccgcag ctagttgatg ttgatgcagc
    15961 cttttttgat actgtttttg aaaattatca attagttgca gaagagtcag gcaagcagtt
    16021 tatctcagtt aatcagatca ataggccctt aaagacggat aaggctttgc tcaagcagct
    16081 gatgaccatt ttgtttgata atgcgatcaa atacactgat cataacggtg tggttgaggt
    16141 caaggttaga acgaccgata agcatttatt gatttctgtt attgataatg gcccagggat
    16201 caaggatgat gataagaaaa agatttttga tcgcttttac cgagtggata aggcaagggc
    16261 acgccaaaaa ggagggtttg gactcggatt ggccttagcg cagcagatcg ttacctcatt
    16321 aaaaggaacg attaccgtca gtgataataa gcctaccggc gccatctttg aagtaaaatt
    16381 atagcactga gttcttgcta gcccataatc agtatgaaaa taacagtcac tagatcaaga
    16441 agtctagtga ctttttttat tgtcttcttt ttgctgttga ccaagcagtt gacaagaaaa
    16501 ttccaataga tagtttaaag ccaataaaac cattattagg cttgcattac aggcaggtat
    16561 caaacaaaga tatagaaaaa tataccataa aaaatctcat aaaagtgtca aaatggtaaa
    16621 aaattgccaa caatatgtcg atattatacc attattatag tataatattt ataatcgtat
    16681 cataatatta aaatatctgg tgtctagctg tttttgtaaa agcaaaaaac ttgcaacacc
    16741 ttatgataaa gcataaagga atacaagcat gatagtctac ctaaagcaac acaaaaatta
    16801 ctggaaatta gtcagcatag ccgctttaat cattatttta ggaggaatac taacaatgaa
    16861 ttggcttaat ggcgaagagc taaaaaagaa aaagtacaga caagagcagg atagggtagt
    16921 gaaatacata ggagagcata tagagctatg taatggtcag cctataacaa aaattgagtt
    16981 tatagaattt cagttagaaa ctgcaaccac cggaacttgg tcaataacaa caattgttaa
    17041 tgagaaatat ctgattcatt tttcagaaga tagattaggt gaagaaatac ggacttccta
    17101 ttattctcca aaagaattta agcaatacag tgaaaagatg aggaataata tgactaatgt
    17161 tgaaacaatt tattacgagg agaaatgatg attgatagag attataaaaa tatttcagag
    17221 gatgtgtata aggttgattc tggtaaagaa agagatccga ttcaagaagg atatccggtt
    17281 gccaatggaa aataccgcgt tcttgaagcc gaagataacc ccgacaatgg tatgcaggct
    17341 atggctgttg tgccaataaa agatggcaaa gaggatagaa gtcatatcgt cattgcctat
    17401 gccgggacaa atagcagtga tatacgcgat attgacaccg atattcaatc cgttgttttt
    17461 ggagatgatc aatacctgtg tacccatgag gagcctgatt cttttaaagt ggtcaagagt
    17521 cagctaagta ctgctaaagc cttttccgac tacattagga caagctaccc taacgctgcc
    17581 atctcctaca ccggacactc tctgggaggc tatctggcac tcatcacagc tgcccatgcc
    17641 aagcagcctg ccactgtctt taatgcgcca agctctgtta ataacctctc caaggaggct
    17701 attgactttg ttaaagccaa caagggactc taccacagct accgcattaa caatgactac
    17761 attggaaatc tgggcactta ctttggagat gatgagctag ggatttcaag atgggttgac
    17821 ggtaaggcgg gaataggacg tcatagctta gccgcttatc gcttcaactc aaagggtcag
    17881 gtgattgacc gtaagggtcg tcctgccgct gctcaagcac ctgctcttgc taccctaagc
    17941 tcaaagctaa ccgaataccg cctgctaaag aaaaagtatg tagcctctaa cggtattagc
    18001 agctcagagg agttttacct tgatcagttt caggctcgag cagtcgcaca ggctttggag
    18061 cagaccactc agcttgccca agaggagatc attgctcgcc ggaaggaggc ggttgcagag
    18121 gcagaggcac ttcaccaaaa gacaagagac atgccctttt ttgtgagtga attgagctgg
    18181 gcggagctag aggaggctta tgcccaggca ggagtgacct atgacagcct tgtgggtcag
    18241 accaagaggc attttgatga caaggttact caagctagag gactggccac aaagttcaag
    18301 accgtaaagg agcagctaga ggagggggtt gagagaacag ctgctattga tcaaaagcta
    18361 ggatgcgact tttcatgaca gcattagaaa agatcagaac tgctatccgt caaaaggaag
    18421 aggagctaga ggagcagcag gagcactatc atcaagagcg gctccaaatg gcagcagccc
    18481 atgacgagtt aagaggcaac tataaccagc tacagcagct ctatgcctct agctatcagg
    18541 ccgttagcag ctacctcaga cattatgatg ctagtctgat aacagaccaa tataccgttc
    18601 taacgaggct gattgatgac taccagcacc gaacagagca gtgctatcat gagcaaggtc
    18661 gcaagatgtc gcagcaggag gaagcaattg accatcacta tcgcagccag cgacaggcga
    18721 tagaaaagga catcacagcg ctgaggcgtc agtggcgtga aggttaagga aaaggagata
    18781 agaaagatga ttgctataga gatgatctta accggacaag agccgatcag gactttaaag
    18841 aaagagctgg ataggagatt agttcagtcc atatgtgctc ccttgacctt aggtcgcctt
    18901 catgcccttc aaaggcgcta tgacagtgag gtatctcgga ttgccacaga caccgcagat
    18961 catattcaga ccattgtcaa tcagctagat agcagcatta gagggca
//
LOCUS       DARYNN010000040        18207 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.040, whole genome shotgun sequence.
ACCESSION   DARYNN010000040 DARYNN010000000
VERSION     DARYNN010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18207)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18207)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18207
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.040"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            94..330
                     /locus_tag="TVB59_001467"
     CDS             94..330
                     /locus_tag="TVB59_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEL1010351.1"
                     /translation="MEVIRTLLMFFSHLLFIGISYQLLISLVDWSKFIHYRPENMGRL
                     RLLVLFLAIASGYLVSRFMLELIQISQYLLYDFH"
     gene            394..1665
                     /gene="murA"
                     /locus_tag="TVB59_001468"
     CDS             394..1665
                     /gene="murA"
                     /locus_tag="TVB59_001468"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEL1010352.1"
                     /translation="MDKIIIEGGSTRLEGEVTIEGAKNAVLPLLAATILPSTGKTVLR
                     NVPILSDVFTMNYVVRGLNIDVDFDEAANQITVDASGDILDVAPYEYVSQMRASIVVL
                     GPILARNGHAKVSMPGGCTIGSRPIDLHLKGLEAMGAEITQQGGDITAKAERLKGAMI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAQLLNKMGAKVRGAGTETLT
                     ITGVTSLCGVEHDVVQDRIEAGTFMIAAAMTSGNVLIRDAVWEHNRPLISKLMEMGVS
                     VVEEDAGIRVQADVTKLRPVTVKTLPHPGFPTDMQAQFTALMAIVKGESTMVETVFEN
                     RFQHLEEMRRMGLQSEVLRDTAMIHGGHELQGAPVMSTDLRASAALILTGMVAKGRTT
                     VNKLNHLDRGYYQFHEKLAKLGANIQRISEE"
     gene            1669..1857
                     /locus_tag="TVB59_001469"
     CDS             1669..1857
                     /locus_tag="TVB59_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEL1010353.1"
                     /translation="MTNGWRYVINQLMLIIAIGLLGLFCLALGLMIGYSLIGDGQNPL
                     AILSPDKWAELIHKFTGK"
     gene            1889..2767
                     /locus_tag="TVB59_001470"
     CDS             1889..2767
                     /locus_tag="TVB59_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL1010354.1"
                     /translation="MIKKKKDIRLLNAFLALLLVLGTGYLAGHDDLAADNPIKQVYQR
                     ILGSDTQQAGLPKASRDWDTPSKALADSVMTATIKQQLGDVITWNGTGAYIINHNKTT
                     LNAKVASLPYANNKTKMVQGQSVPTVANALLTKSTRQYQKRNDTGNGYSSWKPAGWHQ
                     VQGLKGRYSHAVDRGHLLGYALVGGLKGFDASMANPSNIATQTAWANQAANERSTGQN
                     YYETKIRKALDSNKRVRYRVTLLYEGNNLLASGSHLEAKSSDGSLEFNVFIPNVQAGL
                     QIDYQTGQITVASSQP"
     gene            2781..2939
                     /locus_tag="TVB59_001471"
     CDS             2781..2939
                     /locus_tag="TVB59_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010355.1"
                     /translation="MAKADHVASHHGREALVLVVPQRKVLTIFGLVALVEKQIGPLVE
                     APSMPAPD"
     gene            3679..4722
                     /gene="pheS"
                     /locus_tag="TVB59_001472"
     CDS             3679..4722
                     /gene="pheS"
                     /locus_tag="TVB59_001472"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEL1010356.1"
                     /translation="MDLQAQLEELKTKTQEALKQLNGDHSKELQELRVAVLGKKGTLT
                     ELLKGLKDLSNDLRPVVGKQVNELRDFLTQAFEEQAKVVEAAKIQAKLDSESIDVTLP
                     GRQMKQGYRHVLTQISEEIEDIFLGMGFQIVDGFEVEKDYYNFERMNLPKDHPARDMQ
                     DTFYITEDILLRTHTSPVQARTLDQHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQI
                     EGLVVGKSISMGDLKGTLEMIIKKMFGKERKIRLRPSYFPFTEPSVEVDVSCFKCGGK
                     GCNVCKKTGWIEILGAGMVHPSVLEMSGVNAQEYSGFAFGLGQERIAMLRYGINDIRG
                     FYQGDSRFSKQFK"
     gene            4912..7317
                     /locus_tag="TVB59_001473"
     CDS             4912..7317
                     /locus_tag="TVB59_001473"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEL1010357.1"
                     /translation="MLVSYKWLKKLVDIDVSPAELAEKMSTTGIEVEGITSPSEGLSK
                     LVVGHIVSCDAVPETHLHLCQVNTGDDELRQIVCGAPNVKAGINVIVALPGARIADNY
                     KIKKGKIRGMESLGMICSLQELGLPDAIIPKDFSEGIQILPETAAAGDSIFPYLDLDD
                     NIIELSITPNRADALSMRGVAHEVAAIYGKSVSFPEKPLIESAKAAADSLEVAIDSDK
                     VLTYASRIVENVTVKPSPQWLQNLLMNAGIRPINNVVDVTNYVLLYFGQPMHAFDYDT
                     FADHKLLARDAREGERLVTLDGEERVLTTDDIVITVADQPVALAGIMGGKSTEITASS
                     KTVVLEAAVFNGKSIRKTSSRLSLRSESSSRFEKGINHDTLVEALDFAAAMLEELAGG
                     TVLAGRLQAGSLPTNPVEVSTSLDYVNVRLGTALSFTDIEGIFARLGFGISGTAEHFT
                     VSVPRRRWDITIPADLVEEIARIYGYDRLPTTLPEAAGTAAELTKTQALRRQLRGLAE
                     GLGLTEIISYALTTPEKALEFAMKPSQLTELMWPMSVERSVLRQSMVSGMLDTLAYNV
                     ARQQHNLAVYEIGKVFEQEGNPKETLPTELNHFAFAITGLVADKDFQTQAQAVDFYHT
                     KGILECLFDKLGLSVDYIPTKEMASMHPGRTARIQLGDQVIGFVGQVHPQAAKAYHIP
                     ETYVAELDLTAIEAALPAHHAFVEITKYPAMVRDIALLVDASTSHQAILSAITSAKVK
                     RLTEIKLFDIYAGAIIAAGKKSMAYSLTFQNPTDNLTDEEVAGYMEKITKALVEKVGA
                     EVR"
     gene            7552..8628
                     /locus_tag="TVB59_001474"
     CDS             7552..8628
                     /locus_tag="TVB59_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1010358.1"
                     /translation="MFLALNEIKQAKLRYGLIMGLLCLVAYLMFFLSGLAFGLMQENR
                     SAVDSWQADTVLLSKDADANLSLSSLKTSQLKEIKADEVTPLAQLNTVAWSTQAPTEE
                     DKEKISFFGIERESFLKPTITKGRLFKSDKEVVIDQSLAEKGGFKLGDQLRVSASNQT
                     YTIVGYTKNASFNVSPVAYLNLTAFQGLLYGQEAGAQDPNVNAFIIKGKLADYPKEEL
                     QQLTIGDFINKLPGYSAQLLTFGFMIGFLVLISAIIIGIFMYVLTIQKAPIFGIMKAQ
                     GIANRTIANAVLSQTFVLSLLGSSLGLLGTWLSSLVLPATVPFQSNWYLYALILVAMV
                     VFAVLGTLFSVFTIVRIDPLEAIG"
     gene            8638..9342
                     /locus_tag="TVB59_001475"
     CDS             8638..9342
                     /locus_tag="TVB59_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1010359.1"
                     /translation="MTVLAFKQVTKSFKDGDQTIEALKKTDFAIKAGEFVALIGPSGS
                     GKSTFLTIAGGLQTPSSGQFLVNGKDYTNLSEKERSKLRFKDIGFILQASNLIPFLTV
                     KQQLELVDKLTKHKQEAKRQQLFEDLGIAKLANKLPQDLSGGERQRVAIARALYHDPV
                     IILADEPTASLDTEKAFEVVELLAKESKEKNKAIIMVTHDNRMIDYCDKVYRMQDGQL
                     SQDNHHIASNAAMTQN"
     gene            9681..10805
                     /locus_tag="TVB59_001476"
     CDS             9681..10805
                     /locus_tag="TVB59_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK signal domain/LPXTG anchor domain surface
                     protein"
                     /protein_id="HEL1010360.1"
                     /translation="MAKKEMKFYLRKSAFGLASVSAALLVGAAAVSADSVESAGPVAV
                     AVTDSLDSEAAATKAEADLVAAKADLAAAEVAITAAKAEFDTAQADLATAEATIAELE
                     QKIPELEKKIQEAQEKLNYENRPSPKRVGSDDEDDTVARKLMSEKEALKAELQKTKEA
                     LDTAKRAYAGIEERKQVAATKLDAANKAFAGVEEKHAQAMAAFGAAFAAYKEAVKAEL
                     KAAGASDFYTKKIDSADTVDGVKTLREMILDSIAKPEVEPEAKPEPKPEPKPEPKPEP
                     KPEPKPEPKPEPKPEPKPEPKPEPKPEPKPEPKPKPQPKPAPAPKPEAKKEEKKAAPK
                     QDTNKLPSTGEATNPFFTAAALAVMAGAGVAAVSTRRKEN"
     gene            complement(10967..11560)
                     /locus_tag="TVB59_001477"
                     /pseudo
     CDS             complement(10967..11560)
                     /locus_tag="TVB59_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622734.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
     gene            11629..13602
                     /locus_tag="TVB59_001478"
     CDS             11629..13602
                     /locus_tag="TVB59_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cna B-type domain-containing protein"
                     /protein_id="HEL1010361.1"
                     /translation="MKQLTKIVSVVLLLVFTLSASLHKVRATNLSDNITSLTVASSSL
                     RDGERTTVKVAFDDKKQKIKAGDTIEVTWPTSGNVYIQGFNKTIPLNIRGVDVGTLEV
                     TLDKAVFTFNQNIETMHDVSGWGEFDITVRNVTQTTAETSGTTTVKVGNRTATITVTK
                     PEAGTGTSSFYYKTGDMQPNDTERVRWFLLINNNKEWVANTVTVEDDIQGGQTLDMSS
                     FDITVSGYRNERFVGENALTEFHTTFPNSVITATDNHISVRLDQYDASQNTVNIAYKT
                     KITDFDQKEFANNSKIWYQILYKDQVSGQESNHQVANINANGGVDGSRYTSFTVKKIW
                     NDKENQDGKRPKTITVQLYANDQKVNDKTIELSDTNSWQASFGKLDKYDSQNQKITYS
                     VKEVMVPVGYQSQVEGDSGVGFTITNTYTPEVISITGQKTWDDRENQDGKRPKEITVR
                     LLANDAATDKVATASEQTGWKYTFTNLPKYKDGKQITYTIQEDPVADYTTTIQGFDIT
                     NHHEVALTSLKVIKVWNDKDDYYHKRPKEITILLKADGKVIREHQMTPDQQGKWEYTF
                     DQLPVYQAGKKISYSIEEKQVAGYQAPVYEVDEGLKQVTVTNTLNPSYKLPDTGGQGV
                     KWYLLIGGGFIIVAILVLISLYQKHKRHNMSKP"
     gene            13626..15068
                     /locus_tag="TVB59_001479"
     CDS             13626..15068
                     /locus_tag="TVB59_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HEL1010362.1"
                     /translation="MKTIKLILTSLLVTFLTMLSGKAFADTASYTITVEGATAGHTYE
                     AYQIFKGDLFDSTLSNITWGGGVTPFEFDGSKDAAKIAEGLKEANAAAFAKEAGKHLT
                     ATIAGTGTHAITVNEAGYYLIKDKNDSQTGKHDAYTSFVLKVVKNTSFKPKSAIPTVL
                     KKVKDRNDKTGLETGWQDSADYDKNDKVPFQLTATLPSNYDAFQEYYLEFVDTLSKGL
                     SYNKDAKVYVVNGDTRQDITNSFTVSEDGSSFKINNLKAVQGVTITATSKIVVEYTAT
                     LNDQAAIGKKGNPNEVALKYSNDPNALGKGEESPKGETPKDKVIVFTYKTIINKVDQD
                     QKALKGAGFTLYKLVKGDNGEEKYQIVQEIKAGDTTSFEFVGLDAGDYKLSETTTPGG
                     YNTIADVMFSIVAQHETESDDPQLTSLTVDKATGFTADTEAGTVSATIVNKKGSILPS
                     TGSIGTTMLYVFGVMLMTISTLFIFRQKQQ"
     gene            15149..15958
                     /locus_tag="TVB59_001480"
     CDS             15149..15958
                     /locus_tag="TVB59_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HEL1010363.1"
                     /translation="MKKSVIFWSVILVAGCLIVLYPTLSNYWNAQHQSQLIADYVSST
                     QALRHKDSQLMLEAANQYNQQLKANHDPDLTLTDSEAEAYQQQLDLTNTGIMAYIDIP
                     KVHERLPIYHGTDEEILQVAIGHLAGTSLPVGGKGTHAVISGHRGLPSAKLFTNIDKL
                     RINDTFTITSLNRTMTYQVDKIATVLPDDVSLLRIEEGKDLVTLVTCTPYGVNTHRLL
                     VRGHRIKTATPTAARGSQKPSRLILWLLLISALGLSLVLIGTWRWRRRSKA"
     gene            16270..17427
                     /locus_tag="TVB59_001481"
     CDS             16270..17427
                     /locus_tag="TVB59_001481"
                     /EC_number="3.4.22.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678097.1"
                     /note="This family includes IgM or IgG-cleaving cysteine
                     proteases; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IdeS/Mac family cysteine endopeptidase"
                     /protein_id="HEL1010364.1"
                     /translation="MMKKQSFTHSRKPKFGMRKLSIGLASCMLGMMFLTTGHVSGEVV
                     EVWPNGQNPNGKIEILSQTEHSEHLQKLRDIEDFQAQKQADHVRYTKWLDGVTVDEHE
                     FRKIKEYDTEYYVTPLLSGKGYYDINKDFNQDSDKCAAAVAANMFHYWFDRNRDSINR
                     FLSQSPGENGVIKLENEKTIEVSKFLETYRSDGDYLDKSPFFDLISNSFKGPVWANKL
                     LDAYINGYGYIHKFAKNTPHSKNNNSKFNFFKKVFDGNLLTDIHQIFDYNTFSDKLSE
                     ALYTGKAIGLAYGPGDLRRSLGHIISVWGADLDDQNRVVAIYVTDSDDKKLTIGNERV
                     GLKRYKVSSDDQGRARLTTRDKDNTGGEIRSIETLDMGTQEWADYFNKTEK"
     gene            17513..>18207
                     /locus_tag="TVB59_001482"
     CDS             17513..>18207
                     /locus_tag="TVB59_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL1010365.1"
                     /translation="MLTNQTGYRHRLSKQKLPISMVSCLLGMGVLTSPTLISADDSSP
                     TIIIKSGAGMTIDPQLPKTLLSKPEEKPEETPKLPDERHYGDDVRPEETPKLPDERHY
                     GDDIKPEEMPKLPDERHYGDDIRKPKPEDTPKPPNESGQGNDLKEDLELKKQRRELTE
                     QLRALKTIEEVLEFLRKPIPGFVTDEDWNFLVSFVEKGPENKTFEVDKLKLLEIFSTS
                     QGHRVWLGYLILE"
BASE COUNT         5645 a         3666 c         4100 g         4796 t
ORIGIN      
        1 gccctgtgca atacagaact aaatcctttc aataattatt cgtccaactt tttgggggca
       61 gtacatttgt tagacttttg atataataaa gctatggaag taattagaac tcttttaatg
      121 tttttcagcc atttattatt tattggcatt agttatcagc tactcattag cctagttgat
      181 tggtcaaaat tcattcatta ccgaccagag aatatgggaa ggcttcgctt gcttgtcctt
      241 tttttggcaa ttgcctcagg ctatttagtt agtcgcttta tgctggaatt aattcaaatc
      301 agtcagtatc tgctgtatga tttccactag agtaggcagt caggaagtat gatataatat
      361 tagtacgatg accagtagga aatggagaag cttgtggata aaataatcat agaaggtggg
      421 agcacacgtt tagagggaga ggtaacgatc gaaggcgcta aaaatgccgt tcttccttta
      481 ctagcagcta ctatcctccc ctcaactgga aagactgtct tgagaaatgt gccgattctc
      541 tcagatgttt ttacgatgaa ctatgttgtg cgtggcctaa atattgacgt cgactttgat
      601 gaggctgcca accagattac agttgatgcc tcaggggaca ttttagatgt tgccccgtac
      661 gagtatgtca gccaaatgcg cgcctcaatt gtggttttag gcccgatttt agctcgtaat
      721 ggccatgcca aggtatcgat gcctggaggc tgtacgattg gcagtaggcc gatcgatttg
      781 catttaaagg gcctagaggc tatgggcgct gagatcaccc agcagggtgg tgacatcact
      841 gcaaaggctg agcgcctaaa gggggcaatg atctatatgg atttcccatc agtgggggct
      901 acgcaaaatt tgatgatggc agcgaccctt gctgatggtg tgacagtcat tgagaatgct
      961 gctcgcgagc ctgagattgt tgacctagcc cagctgctca acaaaatggg ggctaaggtt
     1021 cgtggggcag gtaccgaaac cctgaccata acgggtgtca ccagtctatg tggggttgag
     1081 catgatgttg ttcaggatcg tatcgaagca ggtaccttta tgattgctgc agcaatgacc
     1141 tccggtaatg tgctgattag agatgctgta tgggagcata atcggccctt gatttctaag
     1201 ctcatggaaa tgggagtgtc tgttgtcgaa gaggatgcag gcattagggt gcaggctgat
     1261 gtgactaaac taaggcctgt cactgttaaa actcttcctc acccaggctt tccaacagat
     1321 atgcaggctc agtttacagc ccttatggcc attgttaagg gagaatctac gatggtggaa
     1381 acagtctttg aaaatcgttt ccagcaccta gaagaaatgc gacgcatggg cttacaatct
     1441 gaggtattgc gtgatacagc tatgattcat ggtggtcacg aattacaggg agcgcctgtg
     1501 atgtcaacag acctgcgagc tagtgcagcc ctcatcttaa cgggaatggt tgccaaaggc
     1561 aggaccactg tgaataaatt gaaccattta gatcgtggct attatcagtt tcatgaaaag
     1621 cttgccaagc taggtgccaa cattcagcga attagtgagg agtagtcaat gactaatggt
     1681 tggagatatg tcataaatca gctaatgcta atcatagcta ttggactgct cggactcttt
     1741 tgtctggcgc tgggactaat gattggctat agccttatcg gtgatggcca aaatccttta
     1801 gcgattttat cgccagataa gtgggctgag ctgattcata aatttacggg aaagtaggca
     1861 tggcctgctt tttatgataa gaggaaagat gatcaaaaag aagaaagaca tcaggctgct
     1921 taatgccttt ttagcgctct tgcttgttct tggaacaggt tatttggcag gacatgatga
     1981 cctagcagct gataacccga tcaagcaggt ctaccaaagg attcttggct ctgacacgca
     2041 gcaagccggg ctaccaaagg caagccgaga ctgggacact ccctccaagg ccttggcaga
     2101 ttcggtcatg acagccacca tcaaacagca attaggtgat gtgattactt ggaatggcac
     2161 tggtgcctat atcattaacc ataataaaac gacgctaaat gcaaaggtag ctagtctccc
     2221 ctatgccaat aataaaacaa agatggtaca agggcaaagc gttcctaccg tagccaatgc
     2281 cctgctaacc aagtcaaccc gacaatatca gaagcgcaat gacactggaa atggctatag
     2341 ctcatggaag cctgctggct ggcatcaggt tcaggggtta aagggaaggt atagtcacgc
     2401 agtggataga gggcatcttc taggctatgc gcttgttggc gggctaaaag gctttgatgc
     2461 ctcaatggct aatcctagta atatcgctac tcaaaccgca tgggctaacc aagcagctaa
     2521 cgagagatca accggacaaa actattatga aacaaaaatt cgcaaagccc tagatagcaa
     2581 taagcgtgtc cgctatcgtg taactttgct ttatgaggga aataatctct tagcaagcgg
     2641 cagtcatctt gaggcaaagt catcagatgg tagcttagaa tttaacgtct ttatccctaa
     2701 tgtacaggct ggattacaga ttgattatca aacaggtcag atcactgtag cttcttccca
     2761 gccttagtga ggcacatcac atggcaaaag ctgatcacgt agctagccat catggcagag
     2821 aagcattagt ccttgtagtc cctcaaagaa aggtgctaac aatatttggt cttgtggctt
     2881 tagtagaaaa acagataggt cctttagtcg aagcaccaag catgccagct cctgattagg
     2941 acaaatgtca aggctaagcg gtggtaagtt aaagtctcac aaaagacaag actggacttt
     3001 tggctatagt cctttatgac tgatgccagc tgataatggc tcaagatgat tgaggtttct
     3061 agcaatgctt gtggctagcc tatcgtctta gttagcgctg attgatgaga tgttgaacag
     3121 ttcttgacta aaagcatccc tacccttacg cctacgtcct ggttagtgaa gaaataagca
     3181 ttgtcataaa ggcatttttt tgatacaata aaagtaattg aatagcagtc tatgagacta
     3241 gtactaatag ggaagttaat agggaatggg ggtcgtgact ggaagccttc ttaatgaaac
     3301 gattaggaat tcactcaatc aaggacgagg taattaaggt ctgacttgct cagatgaaaa
     3361 cggatggtac cgcgtgtcaa cgctccgctt tagataggag ccttgatacg ccttttttga
     3421 tgacgtgctg ttactattag ctatttaatc acaagcaagc actagccagc caaaagtaag
     3481 tgatcactat aagcatagaa agataggagc tgtagcttat ctagaaaagc aagggtgatc
     3541 agtcgtccgc ccaaaagtct ttcttagctt ttgtgatgtg actagctgac ctagctgctc
     3601 acagcttagc ctaaaaggcc tattagcaca aggactgcca gcattaatgc aatcattttc
     3661 caaacagaag ggaatatcat ggatttacaa gcacaattag aagaactgaa aaccaagaca
     3721 caagaagcgc tcaagcagct aaatggtgac cacagcaagg aattacagga gctgcgggtt
     3781 gctgtccttg ggaaaaaagg aacgcttacc gaactgctca agggactaaa ggatctctca
     3841 aatgacctgc gtcctgttgt tggcaaacag gtcaatgagc ttcgtgactt tttgacccaa
     3901 gcctttgaag agcaggctaa ggtggttgag gcagcaaaga ttcaggccaa gctagattct
     3961 gaaagcattg atgtgacttt gccaggccgt cagatgaagc agggctatcg acatgtgctc
     4021 actcaaatca gtgaagaaat tgaggacatt ttcttgggca tgggctttca aattgttgat
     4081 ggctttgagg ttgaaaagga ttattataat tttgaacgca tgaaccttcc aaaggatcat
     4141 ccggctcgtg atatgcaaga caccttctat atcacagagg atattttgct gcgcacccac
     4201 accagtcctg tacaggcacg aacactggac cagcatgatt tttcaaaggg gcctctcaag
     4261 atgatttcac ctggacgtgt tttccgtcgt gacaccgatg atgccactca ttctcatcaa
     4321 tttcaccaaa ttgaaggctt agtcgttggt aagtctattt ctatgggaga cttgaagggg
     4381 actcttgaga tgatcattaa aaagatgttt ggtaaggagc gtaagattcg cctgcgccca
     4441 tcctatttcc cttttactga gccatctgtt gaggttgatg tctcatgctt caaatgtggt
     4501 ggtaaaggct gcaatgtctg caaaaaaaca ggctggattg aaattcttgg agctggtatg
     4561 gtgcacccaa gcgttttaga aatgtcaggt gtgaatgcgc aggagtattc aggctttgcc
     4621 tttgggcttg gtcaagagcg catcgccatg ctgcgctatg gtatcaacga tattcgaggc
     4681 ttctaccaag gagatagtcg cttttctaag cagtttaagt aatagtgatc atatggtcaa
     4741 aaaccaaatc atcagtttga aaaaagaact gacgctcaat ctggagctgt tctttggatt
     4801 agaatcagaa aggaaaaaga cgggtaaaga gcaaagaagt gattggctag cttatctcaa
     4861 gcaggtgcta ggcagatctc tcatcagcgc tcactactct attgaaggct tatgttagta
     4921 tcttataaat ggttgaaaaa attagttgac attgatgtct caccggccga gctagctgaa
     4981 aaaatgtcaa caacaggtat cgaagtagaa ggcatcacca gcccctctga aggtttatca
     5041 aagctagttg ttgggcatat tgtctcatgt gacgctgttc cagaaacgca cctgcacctt
     5101 tgtcaggtca acacaggaga tgatgagctt cgtcaaattg tctgcggtgc acctaatgtc
     5161 aaagcaggga ttaatgtgat tgttgcgctg cctggagctc gtattgcaga caattacaag
     5221 attaaaaagg gtaaaatacg cggtatggag tctcttggca tgatctgctc acttcaggag
     5281 cttggcttac cagatgcgat tattccaaaa gatttttcag aaggtatcca gatcctaccg
     5341 gaaacagcag cagcaggtga tagcattttc ccttaccttg atttagatga caatatcatt
     5401 gagctttcca tcacacctaa tcgtgctgat gccttatcaa tgcgtggtgt tgcccatgag
     5461 gtggcagcta tctatggcaa gtcagtgtca tttccagaaa agccccttat cgaatccgct
     5521 aaagcagcag ctgatagtct agaggttgct attgactctg acaaggtgct gacctatgct
     5581 agtcgtattg ttgaaaatgt caccgtcaag ccaagtccgc aatggctgca aaatcttctg
     5641 atgaacgctg gcattcgtcc aatcaacaat gttgttgatg tgaccaatta tgtcttgctg
     5701 tattttggtc agccaatgca tgcctttgat tatgatacct ttgctgatca taagctttta
     5761 gcgcgtgatg cgcgtgaggg agaaaggctt gtcacccttg atggagaaga gcgtgtgcta
     5821 accacagatg acattgttat taccgtagca gaccagccag tggctctagc tggtattatg
     5881 ggaggcaaat caacagaaat caccgcctcc tcaaagacag tggtgcttga agcagcagtc
     5941 tttaatggca aatcaatccg taaaacaagc agtcggctaa gtcttcgttc agaaagctca
     6001 tcacgctttg aaaaagggat taaccatgac acgcttgtag aggccttaga ttttgcggca
     6061 gccatgctag aagagctagc cggtgggact gttttagcag ggcgcttgca ggcaggctca
     6121 ctgcctacca atccggtaga ggtttcaacc agccttgatt acgtcaatgt ccgcttggga
     6181 acagccttga gctttactga tattgagggg atttttgcaa ggcttggctt tggtattagc
     6241 ggaactgctg aacactttac cgtttcagtg ccacgacgcc ggtgggatat aacaattccg
     6301 gctgacctag tcgaagaaat tgcccgtatc tatggctatg atcgattgcc aaccacatta
     6361 ccagaagctg ctggcacagc cgcagaatta accaaaacac aggcccttcg tcgtcagctg
     6421 cgtggtcttg cagagggact gggtttaaca gaaatcattt cctatgctct aacaacacct
     6481 gaaaaggccc ttgaatttgc aatgaagcca agccagttaa cagagctgat gtggccaatg
     6541 tcagtcgagc gctctgtcct tcgtcaaagc atggtatcag gtatgcttga cacccttgcc
     6601 tacaatgtgg cacgtcaaca gcataacctt gccgtttatg agattggtaa ggtctttgag
     6661 caagagggca atcccaagga gacattacca acagagctta atcactttgc ctttgctatc
     6721 acaggcttag tagcagacaa ggattttcag acacaagcgc aagcggttga tttttaccat
     6781 actaagggaa tcctagagtg tctctttgat aagctaggac tgtctgtgga ttatatccca
     6841 acaaaggaga tggcgagcat gcacccagga cgtaccgcac gtattcagct aggagatcaa
     6901 gtgattggct ttgttggtca ggtgcaccca caggctgcta aggcttatca tatcccagag
     6961 acctatgttg cagagcttga cctgactgct atagaggcag ctctaccagc tcatcatgcc
     7021 tttgtggaaa tcaccaaata cccagctatg gtaagggata ttgccttatt ggttgatgcc
     7081 tcaaccagtc atcaagccat tctttcagcg atcacgtctg ccaaggtaaa gcgtctaaca
     7141 gagattaagc tctttgacat ttacgcagga gcaattattg cggccggtaa aaaatcaatg
     7201 gcctatagcc tgaccttcca aaatccaaca gacaatctga ctgatgagga ggttgccggc
     7261 tacatggaga aaatcaccaa ggccttggta gaaaaggttg gtgcagaggt gagataagga
     7321 cgcttctaat gactagctac ctaaaaaaag ctcatttcaa aggcttagct gcaattgttc
     7381 tgttgcggct gagctttttt tgatgcttag actgtcctta tcctatgcta gttgcagcaa
     7441 gggtttagag atgattttat ttaaattatc agtcaaaaat attttttcta atcaaattcc
     7501 tagctttatc tgatctcctc tgctatactg tgcaataagt aaggagatta tatgttttta
     7561 gccctaaatg aaataaaaca agctaagctc agatatggct tgattatggg actgctctgt
     7621 ttagtagcct atttgatgtt ctttttatcc ggtttagcct ttggattaat gcaggaaaat
     7681 cgctcggcag ttgacagctg gcaggcagat acagttcttt tgtcaaagga cgctgacgcc
     7741 aatctcagcc tatcctcttt aaagaccagt cagcttaagg agatcaaggc tgatgaggtc
     7801 actcccctag cccagctgaa tacagttgct tggtcaaccc aagctccaac agaagaagac
     7861 aaagaaaaaa tcagcttttt tggcattgag agagagtcct ttctcaagcc tacaatcaca
     7921 aaaggaaggc tatttaagtc agacaaagag gtggtgattg atcaaagcct tgctgagaaa
     7981 ggaggcttta agcttggaga tcagctgcgg gtatcggcct ctaaccagac ctataccatc
     8041 gttggctata ccaagaatgc tagctttaac gtgtcacctg ttgcttacct caacctgaca
     8101 gcctttcagg gcttactgta tggtcaagaa gcaggcgcac aagacccaaa tgttaatgcc
     8161 tttattatca aaggcaagct agctgactat cccaaggaag agcttcagca gctaacgatt
     8221 ggcgacttca tcaacaagct gccgggctat agtgcacagc tcttgacctt tggctttatg
     8281 attgggtttt tagtgttaat ctcagccatt atcattggta tttttatgta tgtgctgacc
     8341 attcaaaagg caccaatctt tggtatcatg aaggcacaag gcattgctaa tcgtaccatt
     8401 gcaaatgctg tgctatcaca aacctttgtc ctaagccttt tgggcagcag ccttggccta
     8461 ctaggcacct ggctaagctc gcttgtctta ccagcaacag ttccctttca gagcaattgg
     8521 tacctatatg cgcttatttt agttgctatg gtagtctttg cagtattagg caccctcttt
     8581 tcagtcttta cgattgttag aattgaccct ctagaggcca ttggttagga gaagaatatg
     8641 acagtattag catttaagca ggtcacaaag tcctttaagg acggtgatca gaccattgaa
     8701 gccctgaaaa agacggattt tgcgattaaa gcaggcgagt ttgtcgccct tataggtcca
     8761 tcaggctcag gcaaatcaac ctttctgacc attgcaggtg gtctacaaac accaagctca
     8821 ggacaatttt tagtcaatgg caaggattac accaacctat ctgaaaagga acgatcaaaa
     8881 ctacgcttta aggacattgg ctttatcctg caggcttcta atttgattcc atttttaacc
     8941 gtcaaacagc agctagaatt agttgacaag ttgaccaagc acaagcagga agcaaagcgt
     9001 cagcagctct ttgaggactt gggaatcgct aagctggcta ataagctgcc ccaagattta
     9061 tccggtggcg agcgtcagcg tgttgccatt gccagagccc tataccatga tcctgtgatc
     9121 attttagcag atgagccgac tgccagtctg gatactgaaa aggcctttga ggtcgttgaa
     9181 cttctagcta aagaaagcaa ggaaaaaaac aaggcaatta tcatggtaac ccatgataac
     9241 cgtatgattg actattgcga taaggtctat cgcatgcagg acggccaatt gagtcaagac
     9301 aatcatcata tagctagcaa tgccgcaatg actcaaaact aatcgaatag gaaaagctct
     9361 gctctagcga tatagcaggg ctttttagct gctctaaatt atctcaaaag ttccttttac
     9421 tgatatttaa tattttctgt atttttaatt tatagaaaaa taaagaaaca tgctgagagt
     9481 tgatcaaaac acttactata cttacgatga caagtaactt gctaaagtaa tggttgacat
     9541 ataattgtaa aaaaacagaa ataaaaaaaa aacggtttaa tattgaccta attggcaata
     9601 acgtttacaa taaaggtata attatctgcc gttgataatt aggagacatc atgtctagat
     9661 aaaaacaaaa ggggaataaa atggcaaaaa aagaaatgaa gttttacctt cgtaaatcag
     9721 cctttgggct agcttcagta tcagcagccc tcttggttgg tgcggcagct gtatcagcag
     9781 attctgttga gtcagctggg cctgtagcag ttgctgttac agatagttta gatagtgaag
     9841 ccgcagctac aaaggcagaa gctgatctag ttgctgcaaa agcagaccta gcagcagcag
     9901 aagtagcaat cacagctgca aaagctgaat ttgacaccgc tcaagcagac ctagctaccg
     9961 ctgaagctac tatcgcagag cttgagcaaa aaattcctga gttagagaaa aaaattcaag
    10021 aagctcagga aaaactaaac tatgaaaatc gaccatcacc taaacgtgtg ggcagtgatg
    10081 atgaagatga cacagtagct agaaagctta tgtcagaaaa ggaagctctt aaggctgagc
    10141 ttcaaaagac taaagaagcg ctagatacag ctaaaagagc ttatgctggc atcgaagaaa
    10201 gaaaacaagt agcagcaact aagctagatg cagctaacaa ggcttttgct ggagttgaag
    10261 aaaagcatgc tcaagcaatg gctgcatttg gagcagcatt cgcagcatac aaggaagctg
    10321 ttaaggctga attgaaggca gcaggtgcta gcgacttcta caccaagaag attgactctg
    10381 ccgacacagt tgacggtgtt aagacactca gagaaatgat cttagactca attgctaagc
    10441 cagaggttga accagaggct aagcctgaac ctaagccaga accaaaacct gagccaaaac
    10501 ctgagccaaa accagaacct aagccagaac caaaacctga gcctaagcca gagccaaaac
    10561 cagaacctaa gcctgagcct aagccagaac caaaaccaga acctaagcca aaacctcaac
    10621 ctaaaccagc tccagctcca aaacctgaag ctaagaagga agagaagaaa gcagcgccta
    10681 agcaagacac caacaaattg ccatcaacag gtgaagctac aaatccattc ttcaccgcgg
    10741 cagctcttgc agttatggca ggtgcaggcg tggctgcagt gtcaacaaga cgcaaagaaa
    10801 actaagcctt ataccccagt ggtaaagctt gagcgagaac aatttgttct cgctttttta
    10861 gtgtcttaaa agcacctaca gcaatcatag gtgcttaaca agatatgtct aacgattgct
    10921 atcagctgta gagaataaaa aggagagact aagccttgct cacaagctac ttagaccgaa
    10981 ggagctttag gatttctatg atttgctgag gggagtcctt acagccgcag ctgatccact
    11041 taatgatgat gacctcaata gaggcaatgt atagctcaaa aacatatttt tgggtaactt
    11101 caggataatc ttgtgattct gcacaattca tgaggttgga ataggaaata atatccctaa
    11161 tataatgatt aaaaatttta taaatattag gataataaag gattaagctt tgcatgacct
    11221 cctgattgtc agagaggtag tttaggattt ttaaggtaat agttgtatca agtgatgggg
    11281 attggtaaat gatagaggtg atatcatcta ggtaaacgcc gatcatttcc ctatctaagt
    11341 ccttcttaga gttgaaataa tgttaaaagg ttgttcgact gatattagaa gccttgctaa
    11401 tatctgatac agtaatactg tccttatcct tgtattgtag tagtcggcag tagcttttaa
    11461 ttattttttt acaagtttgt ttatttttat ccattgtatc attaactcct taaaattgaa
    11521 cattaatgtt aattttgtac ataatatttt ttgctaacat tatacaatga tgaacgtgat
    11581 ttgtaaaatt aaattttgca aatcaataat gtaaaaggag gattttgttt gaaacaactg
    11641 acaaagatcg ttagtgtggt cttgttgctg gtctttaccc ttagtgctag cctgcacaag
    11701 gttcgggcaa ctaatcttag tgacaacatc acatcattga cggttgcttc ttcatcactc
    11761 cgagatggag agagaacgac ggtaaaggtt gcgtttgatg acaaaaaaca gaaaatcaag
    11821 gcaggggata cgatagaggt cacctggcct acaagtggta atgtctacat tcagggcttt
    11881 aataaaacca taccgcttaa tattagaggg gtagatgttg gtaccttgga ggtcacgcta
    11941 gacaaggctg ttttcacatt caatcaaaat attgaaacaa tgcatgatgt ctctggttgg
    12001 ggagagtttg atattactgt tagaaatgtg acacaaacca ccgctgaaac atcaggaacg
    12061 accacagtaa aggtaggcaa tcgcactgct actatcactg ttactaagcc tgaggcaggc
    12121 actggtacca gctcatttta ttataagact ggtgatatgc agcccaatga tactgagcgt
    12181 gtgagatggt tcctgctgat taacaacaac aaggaatggg tggccaatac tgttacagtc
    12241 gaagacgata ttcaaggtgg tcaaaccttg gatatgagca gctttgacat caccgtatct
    12301 ggttatcgta acgagcgctt cgttggggaa aacgctctga cagagtttca tacaacattt
    12361 ccaaattctg tcattacggc aacagataat cacattagtg tgcggttaga tcaatatgat
    12421 gcctcacaaa acactgtcaa cattgcttat aagacaaaga taacggactt tgaccaaaaa
    12481 gaatttgcca acaacagtaa aatctggtac cagattttat acaaggatca ggtatcgggt
    12541 caagagtcaa accaccaagt agccaatatc aatgctaacg gcggggttga tggcagtcgc
    12601 tataccagct ttactgtcaa gaaaatttgg aatgacaagg aaaatcaaga cggtaagcgt
    12661 ccaaagacta ttactgttca gctttacgcc aatgatcaga aagttaatga taagaccatt
    12721 gaattgagtg atactaatag ctggcaagca agttttggta agctggataa gtatgacagt
    12781 cagaaccaaa aaattaccta cagtgtcaag gaagtgatgg ttcctgttgg ctaccaatcg
    12841 caggttgagg gggatagtgg agtaggattt accattacca acacctatac accagaggtc
    12901 attagcatta ccggtcaaaa aacttgggac gacagggaaa accaagacgg taaacgtcct
    12961 aaggagatta cggttcgttt attggcaaat gacgctgcaa ctgacaaggt agcaactgct
    13021 tcagagcaaa ccggctggaa gtatacattt accaatctac cgaaatacaa agatggtaaa
    13081 cagatcacct acacgatcca agaggaccct gtggcagatt acaccacaac cattcaggga
    13141 tttgatatta ccaatcatca tgaggtagcc ttgaccagcc taaaggtcat caaggtttgg
    13201 aatgataagg acgattatta ccataaacgt cccaaggaga ttaccatttt gctaaaggca
    13261 gatggcaagg tgattcgtga acatcagatg acaccggatc agcaaggaaa atgggaatac
    13321 acctttgacc agctgccggt ctatcaggca ggcaagaaaa tcagctacag cattgaggaa
    13381 aaacaggttg ctggctatca agcccctgtc tatgaggttg atgaaggctt gaagcaggtc
    13441 actgtaacca acacccttaa cccaagctac aagctgcctg acaccggagg acaaggagtg
    13501 aaatggtacc tgttaatcgg tggcggtttt atcatcgtcg caatccttgt actgatcagc
    13561 ctttatcaaa aacacaagcg ccataacatg tcaaaaccat aacatgtaat agaggagaga
    13621 gagctatgaa aacaatcaaa ttaatcttga cgagcttgct tgtcaccttc ctaacaatgc
    13681 tgtcaggaaa ggcatttgct gatacagcaa gctataccat cactgttgag ggagctacag
    13741 caggtcacac ctatgaggct tatcagattt tcaagggtga cttgtttgac agtaccctat
    13801 caaacatcac atggggaggt ggtgttacac cttttgaatt tgatggttca aaagacgctg
    13861 ctaagattgc agagggattg aaggaagcaa atgcagctgc ctttgccaag gaagcaggta
    13921 agcacttgac agcaaccatt gcaggaacag gaacacatgc aatcaccgtt aacgaggctg
    13981 gctactacct catcaaggac aaaaatgatt ctcaaacagg caagcatgac gcctacacct
    14041 catttgtcct gaaggttgtt aaaaatacca gcttcaaacc aaaatctgct atcccaacag
    14101 tccttaaaaa ggtcaaggac cgtaatgaca agacaggtct tgagacaggc tggcaagatt
    14161 cagctgacta tgacaaaaat gacaaggtgc cattccagct aaccgcaacc ctaccgtcaa
    14221 attacgatgc ctttcaagaa tactaccttg aatttgtaga taccttatca aaagggctaa
    14281 gctacaacaa agacgccaag gtctatgtgg ttaatggaga tactcgtcaa gatattacta
    14341 attcatttac agttagtgaa gatggttcat cttttaaaat caataaccta aaggctgttc
    14401 agggagtaac aataacagct accagtaaga tcgttgtcga atacactgct accctcaatg
    14461 accaagcggc catcggcaaa aaaggaaatc caaacgaagt tgctttgaaa tactcaaacg
    14521 atccaaacgc tcttggaaaa ggagaggagt ctccaaaagg ggagacacca aaagacaagg
    14581 ttatcgtttt cacctataaa actatcatca ataaggttga tcaagatcaa aaagccctaa
    14641 aaggtgcagg ctttaccctt tataagctgg tcaaaggtga taatggcgag gaaaaatatc
    14701 aaatagtcca agaaattaaa gcaggggata caactagctt tgagtttgtt ggacttgacg
    14761 ctggtgatta caagctcagc gaaacaacaa cacctggcgg ttacaacact attgcagatg
    14821 tcatgttcag cattgtagcg cagcatgaaa ccgagtcaga cgatcctcag ttgactagcc
    14881 taaccgttga caaagcaact ggcttcactg ctgatacaga agctggtacc gtatccgcaa
    14941 ctattgttaa taaaaaaggg tctatcctcc cttcgacagg aagtatcgga acaaccatgc
    15001 tctatgtgtt tggagtaatg ctaatgacaa tatcaacgct gtttatcttt cgtcagaaac
    15061 agcaataaga tcgtgtgagt aggtaaaaag aagtggatag acgtcttacc aagacctatt
    15121 cacctctttt tttgatagag gctatagaat gaagaaaagt gtcatttttt ggagtgtgat
    15181 tttggtggca ggctgtctga ttgtccttta ccccaccctt agtaactatt ggaatgcaca
    15241 gcaccaatca cagctcatcg ctgactatgt ctcaagcacg caagctttga gacataagga
    15301 tagtcagctc atgctagaag cagccaatca gtacaatcag cagctaaaag ctaaccatga
    15361 tcctgattta accttgaccg atagtgaggc agaagcctat cagcagcagc tggatctgac
    15421 aaatacaggt atcatggcct acatagatat tccaaaggtg catgagcggc tgccgattta
    15481 tcatggcacc gatgaggaga tcctacaggt ggctatcggt catcttgcag gcacctcttt
    15541 gcctgtaggt ggcaagggaa cacatgctgt catctcagga catcgagggt taccctctgc
    15601 caagctattt accaatattg ataagctgag gattaacgat acctttacca tcaccagtct
    15661 taataggact atgacctatc aggtggataa gattgctacc gttttgcctg atgatgtcag
    15721 cctcttaagg atagaggagg ggaaggatct ggtaaccttg gtcacctgta ccccctacgg
    15781 tgtcaacacg catcggctct tggtcagagg gcatcgtatc aaaacagcga caccaaccgc
    15841 tgcaagagga tctcaaaagc ctagtaggct aatcctctgg ctcttgctaa tcagtgcatt
    15901 agggctatct ctcgtactaa taggcacttg gcgctggcgt aggaggtcta aagcatgagc
    15961 aggctttcca gaagcaacta agtcaaatca tcaacccttg ataggttact gaggacctat
    16021 caggggattt tttagtgcta aattgcgact atgattaaaa acacagaaat cgtttttttt
    16081 tcttagtgac cgaaaacgct ttaaaagagc gagcatttgg agccttcaaa agtgacatct
    16141 gagcataaca tgataaaatt gacttataaa acctaataaa atgataaaag gaggagagtt
    16201 aacgacaaaa tattagatat ttatttaatt tgttgttttt gaaaacgttt tataataaga
    16261 aaggatagca tgatgaaaaa acaatcattc acacactcac gtaaacctaa attcggtatg
    16321 agaaaattat ctattggcct tgcctcatgt atgctaggaa tgatgttcct aacaacagga
    16381 catgtttctg gtgaggtagt tgaagtttgg cctaatgggc aaaatcctaa tggtaaaata
    16441 gaaattctaa gtcaaactga gcactctgag catttacaga aattacgcga tattgaagat
    16501 ttccaagctc aaaagcaagc tgatcatgtt cgttacacta aatggttaga tggggtaact
    16561 gttgatgagc atgaattcag aaaaatcaag gaatatgaca cagaatatta tgtaacacct
    16621 cttttaagtg gtaaaggtta ctatgatatc aataaagatt tcaatcaaga tagtgataaa
    16681 tgtgctgccg ctgtagcggc taatatgttc cattattggt ttgatagaaa tagagacagt
    16741 attaatcgtt tcttaagtca aagtccaggt gaaaatggtg ttattaaact tgaaaatgaa
    16801 aaaacaatag aagtatcaaa atttttagaa acttaccgta gtgatggtga ttatcttgat
    16861 aaaagtccgt tttttgacct tatcagtaac agctttaaag gtcctgtttg ggcaaataag
    16921 ctattggatg cttacattaa cggctatggt tatatccata aatttgctaa aaatactcca
    16981 cattctaaaa ataataatag taaatttaat ttctttaaaa aagtatttga tggtaatctc
    17041 ttgacagata ttcaccaaat ttttgattat aacacttttt cagataaatt aagtgaggct
    17101 ctctatactg gtaaagccat tggattggcc tacggacctg gagacttgcg tcgttcacta
    17161 ggtcatatta tttctgtctg gggagctgat cttgacgatc agaatcgcgt ggtagctatt
    17221 tatgtaactg attctgatga taaaaagtta actataggaa atgagagagt tggtttgaag
    17281 cgatataaag tatctagcga tgatcaaggt cgtgctcgtc tgacgactcg tgataaagat
    17341 aacacaggtg gtgaaattcg atctattgaa acattagata tgggtacaca agagtgggca
    17401 gattacttca acaagacaga aaaataacaa taacccctac acatatatga ttactccaga
    17461 taaagcacac agcaatagac tcagccagta aggaaaggac gataacaaaa cgatgctaac
    17521 aaaccaaacg gggtacaggc atagacttag taagcagaag ctacctatca gcatggtttc
    17581 ctgcttgcta ggaatggggg tgctaacctc tccaacatta atctcagctg atgatagttc
    17641 tcctactatc atcattaaat cgggtgcagg tatgacaatt gatcctcaat taccgaaaac
    17701 tctcctttct aaacccgaag agaaaccaga ggaaacacct aaacttccag atgagcgaca
    17761 ttatggtgat gatgtcagac cggaagaaac accaaagctt ccagacgaga gacattatgg
    17821 tgacgatata aaaccggaag agatgccaaa gctcccagat gagcgacatt atggtgatga
    17881 catcaggaag ccgaaaccgg aggatactcc aaagccacct aatgaaagcg gtcaaggtaa
    17941 tgacttaaaa gaagatttgg agcttaaaaa gcaacgtcga gagcttacag agcagcttcg
    18001 tgctttaaaa actattgagg aagttttaga gttcctgaga aaaccaattc ctggatttgt
    18061 aacagatgaa gattggaatt tcttagtatc atttgtagaa aaaggcccag aaaataaaac
    18121 ttttgaagta gataaattaa aattactaga aatcttctca acctcacaag gtcatagagt
    18181 ttggttaggt taccttattc tggaaga
//
LOCUS       DARYNN010000041        17855 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.041, whole genome shotgun sequence.
ACCESSION   DARYNN010000041 DARYNN010000000
VERSION     DARYNN010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17855)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17855)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17855
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.041"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(220..1320)
                     /locus_tag="TVB59_001483"
     CDS             complement(220..1320)
                     /locus_tag="TVB59_001483"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEL1010366.1"
                     /translation="MISSLHRPTVARVDLEAIRANIDHIHQHIPKKVRTYAVVKANAY
                     GHGAVAVSKAVEDQVDGYCVSNLDEALELRQAGIDKEILILGVILASELQLAIKHQLT
                     ITVASLEWLELAKKESVDFSQLHVHVKVDSGMGRIGVRSLAEANQLISILSDMGVQLD
                     GIFTHFATADDSDHAMFDKQLTFFKQLVEQLDKRPALVHASNSATSLWHSETIFNAIR
                     LGIVIYGLNPSGNSLSLPCPLKEALSLESRLVHVKQIQAGDSVGYGASYVAAEPEYVG
                     TLPIGYADGWTRNMQGFKVLVEGEFCDIIGRVSMDQLTIRLPKAYPIGTKVTLIGQQG
                     KQVITATDVADYRGTINYEVLCLLSDRIPREY"
     gene            complement(1317..1673)
                     /locus_tag="TVB59_001484"
     CDS             complement(1317..1673)
                     /locus_tag="TVB59_001484"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEL1010367.1"
                     /translation="MIVGHGIDLQDISAIEKVYLRNARFARKVLTDKELALFEQFSHH
                     RKMTYLAGRWAGKEAFSKAMGTGIGQLTFQDIEIINDSKGRPVITKSPFQGKAFISIS
                     HSGGYVQASVILEDLA"
     gene            complement(1789..4317)
                     /gene="secA"
                     /locus_tag="TVB59_001485"
     CDS             complement(1789..4317)
                     /gene="secA"
                     /locus_tag="TVB59_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEL1010368.1"
                     /translation="MSNILRKVIENDKGELRKLEKIAKKVESYADYMESLSDKDLQAK
                     TPEFKQRYQNGETLEQLLPEAFAVVREAARRVLGLYPYRVQIMGGVVLHNGDVPEMRT
                     GEGKTLTATMPVYLNALAGEGVHVITVNEYLSTRDATEMGEVYSWLGLSVGINLAAKS
                     PAEKREAYLCDITYSTNSEVGFDYLRDNMVVRQEDMVQRPLNFALVDEVDSVLIDEAR
                     TPLIVSGAVSSETNQLYIRADMFVKTLDSVDYIIDVPTKTIGLSDSGIDKAESYFNLS
                     NLYDIENVALTHFVDNALRANYIMLLDIDYVVSEEGEILIVDQFTGRTMEGRRFSDGL
                     HQAIEAKEGVRIQEESKTSASITYQNMFRMYKKLAGMTGTAKTEEEEFREVYNMRIIP
                     IPTNRPIARIDHTDLLYATLNSKFKAVVADVKARYEKGQPVLVGTVAVETSDLISKKL
                     VEAGIPHEVLNAKNHFKEAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDELMRRFGTDRIKAFLDRMNNDD
                     EDIVIKSRMLSRQVESAQKRVEGNNYDTRKQVLQYDDVMREQREIIYANRRDVITANR
                     DLGPEIKAMIKRTIDRAVDAHSRTNRKDAIDAIVTFARTSIVPEETIGAKELRGLKDD
                     QIKDKLYQRALEIYDKQLSKLRDQDAILEFQKVLILMIVDNKWTEHIDALDQLRNAVG
                     LRGYAQNNPVVEYQSEGFKMFQDMIGAIEFDVTRTMMKAQIHEQERERAIQYATTTAA
                     QNIQSQAIGADFDSSADFSRVERNDACPCHSGKKFKNCHGRKAF"
     gene            complement(4693..5637)
                     /gene="manA"
                     /locus_tag="TVB59_001486"
     CDS             complement(4693..5637)
                     /gene="manA"
                     /locus_tag="TVB59_001486"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEL1010369.1"
                     /translation="MSEPLFLTSCMHDKIWGGTKLREVFGYELPTETTGEYWAISAHP
                     NGVSTVSSGSYQGQRLDQLYAERPELFGNPKEKVFPLLTKILDANDWLSVQVHPDDAY
                     GLAHEGELGKTECWYIISAEEGAEIVYGHHASSKQELRAMIEAGNWEELLTRVPVKAG
                     DFFYVPSGTMHAIGKGILILETQQSSDTTYRVYDFDRRDAEGQLRELHIEKSIDVLTI
                     GKPENSTPATLELEHLVSTCLVSNPFFTVYKWEIDQAVSMKQSAPYLLVSVLAGQGSL
                     TIDQAVYELQKGMHFILPNDVTSWSFDGQLEMIVSHPN"
     gene            complement(5753..6637)
                     /locus_tag="TVB59_001487"
     CDS             complement(5753..6637)
                     /locus_tag="TVB59_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEL1010370.1"
                     /translation="MKTLLGSIEAGGTKFVCAVGDRDFAVVDKVQFPTTSPKETIERT
                     IAYFKQFEADLASIAIGSFGPIDIDPKSATYGYITTTPKPGWANVDLLGQLTAAFAIP
                     FYVTTDVNSSAYGEAISRPDVDSLVYYTIGTGIGAGAIQKGEFIGGLGHTEAGHTYVM
                     QHLDDVANAFLGVCPFHRGCLEGMAAGPSLEARAGIKGELLDQKAAVWDIQAFYIAQA
                     AVQATLLYRPQVIVFGGGVMAQEHMLVRVQEAFTRLINGYLPVADVREYLVTPAVAGN
                     GSATLGNFALAKLIAEKS"
     gene            complement(6994..10050)
                     /locus_tag="TVB59_001488"
     CDS             complement(6994..10050)
                     /locus_tag="TVB59_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEL1010371.1"
                     /translation="MEKQVLVKKTLKCVCAAALMVAILAAQHDSLIRVKAEDKVVQTS
                     PSVSAIDDLHYLSENSKKEFKEGLSKAGEVPEKLKDILSKAQQADKQAKVLAEMKVPE
                     KIAMKPLKGPLYGGYFRTWHDKTSDPAEKDKVNSMGELPKEVDLAFVFHDWTKDYSFF
                     WQELATKHVPTLNKQGTRVIRTIPWRFLAGGDHSGIAEDTQKYPNTPEGNKALAKAIV
                     DEYVYKYNLDGLDVDIERDSIPKVNGKESNENIQRSIAVFEEIGKLIGPKGADKSRLF
                     IMDSTYMADKNPLIERGAQYIDLLLVQVYGTQGEKGDWDPVARKPEKTMEERWESYSK
                     YIRPEQYMVGFSFYEENAGSGNLWYDINERKDDHNPLNSEIAGTRAERYAKWQPKTGG
                     VKGGIFSYAIDRDGVAHQPKKVSDDEKRTNKAIKDITDGIVKSDYKVSKALKKVMEND
                     KSYELIDQKDFPDKALREAVIAQVGSRRGDLERFNGTLRLDNPDIKSLEGLNKLKKLA
                     KLELIGLSQITKLDSLVLPANAKPTKDTLANVLEAYGSAKKEETKAIPQVALTISGLT
                     GLKELNLAGFDRDSLAGIDAASLTSLEKVDLSSNKLDLAAGTENRQILDTMLATVTKH
                     GGVSEKTFVFDHQKPTGLYPDTYGTKSLQLPVANDTIDLQAKLLFGTVTNQGTLINSE
                     ADYKAYQEQEIAGHRFVDSSYDYKAFAVTYKDYKIKVTDSTLGVTDHKDLSTSKEETY
                     KVEFFSPTNSTKPVHEAKVVVGAEKTMMVNLAEGATVIGGDADPTNAKKVFDGLLNND
                     TTILSTSNKASIIFELKEPGLVKYWRFFNDSKISKADCIKEAKLEAFVGHLEAGSKVK
                     DSLEKSSKWVTVSDYSGEDQEFSQPLNNIGAKYWRITVDTKGGRYNWPSLPELQIIGY
                     QLPAADLVMAMLATAEELSQQKDKFSQEQLKELEVKIAALKAALDSKMFNADAINAST
                     ADLKAYVDKLLADRTDQEKVAKAAKVEQPVATDIKENTEPENPKTD"
     gene            complement(10279..12162)
                     /locus_tag="TVB59_001489"
     CDS             complement(10279..12162)
                     /locus_tag="TVB59_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEL1010372.1"
                     /translation="MDNHQIAKEVIEALGGRENVRSVAHCATRLRVMVHDEGKINKEK
                     AEAIDKVKGAFFNSGQYQLIFGTGTVNSIYDEVVALGLPAALAGEQKEQVVKSGNAFQ
                     RAIRTFGDVFVPIIPAIVAIGLFMGVRGLLTQPAVMEFFGIHDYGDNFLMYTRILTDT
                     AFVYLPALVAWSAFRVFGGNPIIGIVLGLMLVSNELPNAWVVASGGDVKPLTFFGFVP
                     VVGYQGTVLPAFFVGLVGAKLEKWLHKRVPDALDLLATPFLTFAIMSALGLFVIGPIF
                     HSLENLVLAGTQAVLGLPFGIAGLVIGGVQQLIVVTGIHHIFNFLEAQLVANTGKDPF
                     NAYLTAATAAQAGATLAVAVKTKSAKLKGLAFPSALSALLGITEPAIFGVNLRYPKVF
                     VSGLIGGAAGGWVAGILGIAGTGFGITVLPGALLYLNGQLLQYLVTLLVGLGLAFVIA
                     YIWGFKDKSDQEAPATQVKSEPAQKASAAEELLSPVAGELIDLSSVADPVFSSGSMGQ
                     GVAIKPEGRILCSPVDGRVEAALETGHAYVIKSDKGAEILLHIGIDTVSMAGEGFETF
                     VKVGQMVKAGDALGSFDIARIQQAGLDTTTMLLVTNSADVHAVQILAQGKVTVGSPVI
                     LVK"
     gene            12439..13878
                     /locus_tag="TVB59_001490"
     CDS             12439..13878
                     /locus_tag="TVB59_001490"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HEL1010373.1"
                     /translation="MDLPRSIRYRPYQEWSKEAYQAIQQKVAQSLWRSHFHIEARTGL
                     LNDPNGFSYFAGSFQLFYQNWPFGAAHGLKQWVHTTSTDLVHFTETKTRLLPDHQNDS
                     HGAYSGSAYPIGDKLFLCYTGNVRSKDWVRHPLQIGAWMDQSGHITKCEQVLIDKPDD
                     VTEHFRDPQLFTYQDQLYAIIGAQNLQQQGIIKLYKANNNDVTSWQFVADLDFDDSGT
                     AYMIECPNLVFIEDKPVLIFCPQGLAKSELDYQNIYPNTYKVFQTFDPKRRKLLGGGP
                     IQNLDFGFEAYATQAFNSPDGRVLAVSWIGLPDIDYPTDKYAYQGALSLVKELRLKNG
                     RLHQAPVPALSKLRDKAQPFQNKKNSSNCYELALTIEAQQATELLLFADTQHKGLKLT
                     VDTCKGQLTIDRSKAGAQYAQEFGAKRSCQIPVNRATLNIYVDKSILEIFVNQGEAVL
                     TSRVFPNEGQSGIELLKGQVSGYYYEMRY"
     gene            13883..14848
                     /locus_tag="TVB59_001491"
     CDS             13883..14848
                     /locus_tag="TVB59_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1010374.1"
                     /translation="MVAKLTDVAALAGVSPTTVSRVINKKGYLSQKTIDKVNKAMREL
                     GYKPNNLARSLQGKSPQLIGLIFPNISNIFYAELIEHLEIELFKQGYKAIICNSENNP
                     IKERDYLEMLAANQVDGIISSSHNLGIDDYERVEAPIVAFDRNLAPHIPIISSDNFEG
                     GKLAAKTLQKHGCQKMIMITGNDHSDSPTGLRQLGFNYQLKKGADIIKLPNDLSSIRR
                     EMEIKSILATRRPDGIFASDDLTAILIMKVAGQLGIAIPDNLKLIGYDGTAFIEHYFP
                     QLTTIKQPIKEIASLTVEVLLKKIGNEKTSKDYVLPITLLPGGSL"
     gene            complement(15225..15731)
                     /locus_tag="TVB59_001492"
     CDS             complement(15225..15731)
                     /locus_tag="TVB59_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010375.1"
                     /translation="MKRKILLLMMLLVGVFIFSKRYELYYFFQGKEYLRPNESIELAV
                     RPKYEQIEYSSDLYLESDEKVLLKLEGRDIWSEYIYRRTDSYLSKIGYRYSITEQVIE
                     KYDSTKDNGVVIVEAGHKGATIDGDGLIVPLKGKRKYSVTEDHDYSITITNLSDQPVA
                     FRAIVADR"
     gene            complement(15728..17134)
                     /locus_tag="TVB59_001493"
                     /pseudo
     CDS             complement(15728..17134)
                     /locus_tag="TVB59_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515913.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(17125..17484)
                     /locus_tag="TVB59_001494"
                     /pseudo
     CDS             complement(17125..17484)
                     /locus_tag="TVB59_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515008.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(17496..17762)
                     /locus_tag="TVB59_001495"
     CDS             complement(17496..17762)
                     /locus_tag="TVB59_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04197 family type VII secretion effector"
                     /protein_id="HEL1010376.1"
                     /translation="MSDTITSSPVAASAAISELVGVDTSRVHQQSVAFSVTKGIAGME
                     KGRQVSNQLLQAVSDFSQAVLIQANKFPQLAAKLEKRDLEEATR"
BASE COUNT         5023 a         4424 c         3375 g         5033 t
ORIGIN      
        1 tgaagcaaaa taaaatgcaa gattttttgt attaatgcct taatactcgg ataaaggtaa
       61 gggccttttc ttattctttt tcttaacccg cagaaaaaca agacctgtct tgatctgctc
      121 tatctatgct gttagcctga ggtctcaaga cctttacagg actaatcatt tgaaagacag
      181 ccttgaggcc agtcaatagt tgagcctagg ctcaatttcc taatattctc taggaatacg
      241 atcactcagc aagcaaagca cctcataatt aatcgtacct ctataatcgg caacatcggt
      301 tgctgtgatt acttgtttac cctgctgtcc aatcaaggtc accttagtgc cgataggata
      361 ggctttaggc aaacgaatgg tcaattggtc catcgacaca cgaccaataa tgtcacaaaa
      421 ttccccttct accaatacct taaagccctg catatttcga gtccaaccgt cagcatagcc
      481 gataggtaag gtcccgacat actctggttc tgctgctaca tagctagctc catagccaac
      541 gctatcccct gcctgaattt gcttcacatg aaccaaacgt gattctaagg acaaggcttc
      601 ctttaaggga caaggtagac tcaagctatt gccgcttgga ttgagtccat agataacaat
      661 accaaggcga atggcattaa aaattgtttc actatgccaa aggcttgttg cagagttgct
      721 tgcatgcact aatgcaggcc tcttatctag ctgctccacc aactgcttga aaaaggtcag
      781 ctgcttatcg aacatggcat ggtcagagtc atctgcggtt gcaaaatgcg tgaaaatccc
      841 gtcaagctgc actcccatat cggataagat tgagatgagc tgattggcct cagcaagcga
      901 cctgacacca atgcgcccca ttcccgagtc aaccttgaca tgcacatgaa gctgactgaa
      961 atcaaccgat tcctttttgg caagctctag ccactctaag ctggccactg ttatcgtcag
     1021 ctgatgctta atggctagct gcaattcact tgctaaaatc acccctaaaa taaggatttc
     1081 cttatcaatg cctgcctgac gtaattccaa ggcttcatca aggtttgata cgcaatagcc
     1141 atcaacctga tcctcaactg ccttggacac tgcaactgcc ccatgaccat aagcattggc
     1201 cttgacaaca gcatatgtcc ttaccttttt aggaatatgc tgatgaatat ggtcaatatt
     1261 tgctcgaata gcttctaagt caactctagc tactgttggt cgatgtaagc ttgaaatcat
     1321 gctaaatcct ccaaaataac acttgcttga acatagcccc cactatgtga aatactgata
     1381 aaggccttac cctgaaaggg agattttgta atgacgggac gccctttgct gtcattgata
     1441 atttcaatat cctgaaaggt tagctggcca atccctgtcc ccattgcctt tgaaaaggcc
     1501 tccttaccag cccagcggcc ggccagatag gtcatttttc ggtgatggga aaattgctca
     1561 aacagcgcta gctccttgtc cgtcaaaacc tttctagcaa atctagcatt tctcaaataa
     1621 accttttcaa tagctgaaat atcctgtaaa tctatcccat gtccaacaat catttgcctt
     1681 tattttacca gccttcactt taatttaggg aaacaaatcc taaacaagga gaagccgaga
     1741 acaaatctca gctcctcaca ggttttcaac atggccatca cgctatcctt aaaaagcctt
     1801 acgaccatga cagtttttaa acttcttacc agagtgacaa ggacaagcat cattgcgctc
     1861 gactcttgaa aaatcagctg atgaatcaaa atcagcaccg atagcctgcg actgaatgtt
     1921 ttgtgctgca gttgttgttg catactgaat tgcacgctcg cgctcctgct catgaatctg
     1981 tgccttcatc atggtacgtg taacatcaaa ttcgatagca ccaatcatat cctgaaacat
     2041 cttgaagcct tcactttgat attcaacaac tggattattt tgcgcataac cacgcaaacc
     2101 aaccgcatta cgaagctggt ctaaggcatc aatatgctct gtccatttgt tgtcaacaat
     2161 catcaaaatc agcaccttct ggaattctaa gatagcgtcc tgatcgcgca attttgataa
     2221 ctgcttatcg taaatctcaa gggcacgctg atagagcttg tctttgatct gatcgtcctt
     2281 gaggccacgc aattccttag caccgatggt ttcctctggg acaattgatg ttctcgcaaa
     2341 agtcacgatg gcgtcaatag cgtccttacg attggtacgt gagtgggcat caactgctcg
     2401 atcaatcgta cgcttgatca ttgccttaat ttcaggacct aggtcacgat ttgctgtgat
     2461 aacatcacga cggttagcgt aaataatctc acgctgctca cgcatcacat catcatactg
     2521 caagacctgc ttacgtgtgt catagttatt accctcaaca cgtttttgag ctgactccac
     2581 ctggcgtgac agcattctgg acttgataac aatatcctcg tcatcattgt tcatacgatc
     2641 caagaaagcc ttaatacggt ctgtaccaaa gcgcctcatc agctcgtcct ctaaggagag
     2701 gtagaattgt gactcccctg gatctccctg acgacctgaa cgcccacgaa gctgattatc
     2761 aatacggcgg ctctcatgac gctctgtccc gataacacaa agcccaccga gctctcggac
     2821 accctcaccg agcttaatgt ctgtcccacg accagccata ttggtcgcaa tcgttaccgc
     2881 accacgctga ccagcattca taataatctg tgcttcttta aagtggttct tagcatttaa
     2941 gacctcatgc ggaatgcctg cttctactag ctttttagaa atcaggtcac tggtctcaac
     3001 agcaactgta ccaactagaa cgggctgccc cttttcatag cgagccttaa catctgcaac
     3061 cactgccttg aattttgaat tcaacgttgc ataaagaagg tctgtgtgat caatacgagc
     3121 aataggacgg ttggttggaa tcggaataat acgcatgttg taaacttcgc ggaattcctc
     3181 ttcctccgtt tttgctgtac cagtcatacc cgccaatttc ttatacatac ggaacatgtt
     3241 ttggtaggta atagaggcac ttgtttttga ttcctcttga atacgaacgc cctcttttgc
     3301 ctcaatagct tggtgtaagc catccgaaaa gcgtcgtccc tccattgtac gacctgtaaa
     3361 ctggtctaca atcaaaatct cgccttcctc gctaaccaca taatcaatat ccaaaagcat
     3421 gatataatta gcacgaaggg cattatccac gaagtgggtc aaggcaacat tttcaatatc
     3481 gtataggttg ctgaggttga aatagctttc tgccttatca atacctgagt cgcttaggcc
     3541 aatcgtcttg gtcggaacat caatgatgta atccactgaa tccaaggtct tgacaaacat
     3601 gtctgcacga atatagagct gattcgtttc tgagctcaca gcaccagata caatcagagg
     3661 tgttcttgcc tcgtcaatca aaacagagtc aacctcatcg accaaggcaa agttcagtgg
     3721 tcgctgaacc atgtcctctt gacgaaccac catattatca cgcaggtagt caaagcctac
     3781 ctcagagttg gttgagtagg taatatcaca tagataagcc tcacgctttt cagctggtga
     3841 tttggctgct aggttgatac cgactgaaag ccctagccag ctatacacct ctcccatctc
     3901 tgtcgcgtca cgagttgaca agtattcatt aacagtgata acgtgtaccc cttcgccagc
     3961 aagggcatta aggtaaacag gcatggtcgc tgtaagggtc ttaccttcac cggtacgcat
     4021 ctcagggaca tctccattgt gcaagacaac cccccccatg atctgaacac gataagggta
     4081 aagtcccagc acacgtctag ccgcctcgcg gacaaccgca aatgcttctg gtaataactg
     4141 ctcaagggtt tccccatttt gataacgttg tttaaattcg ggcgtttttg cttgtaggtc
     4201 tttatctgac aaggactcca tatagtcagc ataggactct acttttttcg caattttttc
     4261 taattttcgt aattcgcctt tatcattttc aatgactttg cgtagaatat tgctcattct
     4321 ctttcctttc gatcgactaa tcattttatt ctaacataaa taggcaggca gttcaagaaa
     4381 tgatcataag atatccatga cagacgcatg aagaaaatca tttattgaaa aagttgtgaa
     4441 aatagcaaaa tagccatttt agggtatttg acagagtgtt tcctgaattg ttatattctc
     4501 cctctataaa cttttcttga aaaatttctt ttctgcaact atcgctatgg ctttcctatt
     4561 tttcagaata agttttcgca ttcagaaata tcttggaaat tttttcttca tgcgtctgtc
     4621 gtgataagat atcagaaaaa gaaaggccgc ttgtccaaac agtctttctt ggtgttttcg
     4681 tgtattctgt acttaattag gatgactgac aatcatttcc agctgaccat caaagctcca
     4741 tgacgtcaca tcatttggca ggataaaatg catacccttt tgaagctcgt aaacagcttg
     4801 atcaatcgta aggcttccct gaccagctag cacactgaca agcaggtaag gggctgattg
     4861 cttcatgctg actgcttgat caatctccca tttgtaaact gtaaagaagg gattagatac
     4921 taagcaggta gagaccaagt gctcaagttc tagtgtggct ggcgtgctgt tctcaggctt
     4981 gccaatagtt aggacatcga tagatttctc aatatggagc tcacgaagct gaccttcagc
     5041 gtctcgacga tcaaaatcat aaacgcgata ggtcgtgtct gaggattgct gcgtctctaa
     5101 gatcaaaatt cccttaccaa tggcatgcat cgtgccgctt ggaacataga agaaatcacc
     5161 agccttaacc ggaactcgcg tcaacaactc ttcccagttc cccgcctcaa tcatcgcacg
     5221 aagctcttgt ttagagcttg catgatgacc ataaacaatc tcagcgcctt cttcagctga
     5281 aataatatac cagcattccg tctttcctag ctctccctca tgggccagcc cataagcatc
     5341 atctgggtgt acctgaacgc ttagccagtc attagcatct aaaatcttcg tcaacagcgg
     5401 aaagaccttt tcctttggat ttccaaatag ctctggtctt tctgcataaa gctgatctag
     5461 cctttggcct tggtagctac cactgctaac tgtggaaaca ccattagggt gagctgagat
     5521 tgcccaatac tccccagtgg tttcggttgg aagctcatac ccaaacacct ctcttagctt
     5581 tgttccgccc cagatcttat catgcatgca tgatgttaaa aataatggtt ctgacatagt
     5641 aatcctcatt ctcttttcac taacctatgg tgacattctt tgccccaatt ctaccaattt
     5701 caggcacatt ttgcaaatga ctctaggact tttatcaaat aggctcaagt atctagctct
     5761 tttcagcaat cagctttgct aaagcaaaat tcccaagagt ggccgagcca ttacctgcaa
     5821 ctgctggtgt gaccaaatat tctctaacat cagctactgg taaataacca ttaatcagtc
     5881 tggtaaaggc ctcctgaaca cgcaccagca tgtgctcctg tgccatcaca cctccaccaa
     5941 acacaataac ctgaggacga taaagcagcg ttgcctgtac agcagcctga gctatataga
     6001 aggcttgaat atcccaaaca gcggccttct gatcaagaag ctccccctta atccctgccc
     6061 ttgcttcaag gcttggccct gctgccatgc cctctaagca cccccgatga aatggacaaa
     6121 cacccaaaaa tgcattcgcc acatcgtcaa ggtgctgcat aacataggta tgtcccgcct
     6181 ctgtatgacc taacccaccg ataaactcac ctttttgaat agctccagca ccaatacctg
     6241 ttccaatcgt ataataaaca agactgtcaa catcaggtcg agagatagcc tccccatagg
     6301 cagaactatt aacatcagtc gtcacataaa aaggaatcgc aaaggctgct gtcagctgcc
     6361 ctaatagatc tacatttgcc caacctggct tgggtgttgt ggtaatgtag ccataggtag
     6421 ctgacttagg atcaatatca atcggtccaa aggagccaat agcaatacta gccaagtcgg
     6481 cctcaaattg cttaaaataa gcaatcgtac gctcaatagt ctcttttgga cttgtcgttg
     6541 gaaattgcac cttatccaca acagcaaaat ccctatcacc aacagcacag acaaactttg
     6601 tcccgcctgc ttcaatactt ccaagtaatg ttttcatctt ttctccttaa taatagtgat
     6661 aagccctgtg ctggttattc tcacaaggct caaaatccca ccagctaatc agcagctacc
     6721 ttagtagcta aacatcatcg cttgcttcct tgcctcctag aaaagaccaa aaatctggga
     6781 taggactatc tcagattttt gatatgcctt taagagataa ggcaattgat tttaggaggg
     6841 aaaccttggc agcaggagct gccaccaaga agcagcacaa acaattgctt ttaatggtgt
     6901 gttcatcgcc ttatctctaa agcttaatgt gttagcgtaa tgatcagtaa cctcaagcta
     6961 acggccaaga acgacagcct gctcaaggat aagctagtct gtctttggat tttctggctc
     7021 agtattttct tttatgtcag tagccacagg ctgctcaact ttagctgctt tagctacttt
     7081 ttcctgatca gttctatcag ctaaaagctt atcaacataa gccttcagat cagcagtact
     7141 agcgttaata gcatcggcat taaacatctt actatctaaa gcagccttta aggcagctat
     7201 tttgacttcg agctccttaa gctgctcttg agagaacttg tctttttgct gagatagctc
     7261 ctctgcagta gctagcattg ccatcacaag atccgcagcc ggtaattgat aaccaatgat
     7321 ttgaagctca ggaagtgatg gccaattgta acgtcctccc ttagtatcaa ctgttattct
     7381 ccaatatttg gcaccaatgt tgtttaacgg ctggctaaac tcttggtcct ctcctgaata
     7441 atctgaaact gttacccatt ttgatgattt ttccaagcta tcctttacct ttgagccagc
     7501 ttcaagatgg ccaacaaagg cttcaagctt ggcctcctta atacagtcag ctttactaat
     7561 tttgctgtca ttaaagaaac gccaatactt gactaagcca ggctctttaa gttcaaaaat
     7621 gatagaagct ttattgctag ttgacagaat tgttgtatca ttattgagca aaccatcaaa
     7681 cacttttttt gcatttgttg gatctgcatc accaccaatc acagttgctc cctctgctag
     7741 gttaaccatc atggtttttt ccgcaccaac gacaacctta gcctcatgca caggcttagt
     7801 gctattagta gggctaaaga attcaacctt gtaggtctcc tccttgctag tggataagtc
     7861 cttgtgatca gtgacaccta aggttgagtc agtcaccttg atcttatagt ccttgtaggt
     7921 cactgcaaag gctttgtaat catagcttga atcaacaaaa cggtgacctg ctatttcctg
     7981 ctcctgataa gccttatagt cagcttcgct attgattagc gtgccctgat tggtaactgt
     8041 tccaaataaa agcttagcct gcaaatcaat tgtatcattt gctactggta actgaaggct
     8101 cttagtgcca taagtatcag gataaagacc agtaggcttt tgatgatcaa atacaaacgt
     8161 cttttcgcta acaccgccat gcttagtcac tgttgccagc atggtatcaa gaatctgacg
     8221 attttccgta ccagctgcta agtccagctt attactagag agatccacct tttcaagaga
     8281 ggttaggcta gctgcgtcaa ttccagccaa gctatcacga tcaaagccag caagatttaa
     8341 ttccttcaag ccagttagac cagaaatggt cagagccacc tgtggaatcg ccttagtctc
     8401 ttccttctta gcgctgccgt aggcttcaag aacattggcc agcgtatcct tggtcggctt
     8461 agcatttgca ggtaggacta agctatccag ctttgtgatt tgtgatagac cgattagctc
     8521 tagcttagct agttttttaa gcttattcag gccttctaaa ctcttgatat ccggattgtc
     8581 taagcgcagg gttccattga accgctctaa atcccctctt ctgcttccaa cctgtgcaat
     8641 aactgcttct cgcaaagcct tgtctggaaa atctttctga tcaatcagct cataggattt
     8701 gtcattttcc ataaccttct tcaaggcctt agaaacctta taatctgatt tgacaatacc
     8761 atctgttata tcctttatag ccttgttagt tcttttctca tcatctgaga cttttttagg
     8821 ttgatgcgct acaccatcgc gatcaatcgc ataagagaaa atccctccct tgacaccacc
     8881 tgtcttaggc tgccattttg cataacgctc agcacgagta ccagctatct ctgaatttaa
     8941 cggattatga tcatctttcc tctcattaat atcataccag aggttaccac tgcccgcatt
     9001 ttcctcatag aaagaaaaac caaccatgta ctgctcagga cgaatgtatt tgctatacga
     9061 ttcccaacgt tcctccattg tcttttcagg ttttctagcg actggatccc aatctccctt
     9121 ctcaccttga gtgccataaa cctgcacaag cagcaaatca atatattggg caccgcgctc
     9181 aatcaatggg ttcttgtcag ccatgtaggt gctatccata atgaacaaac gtgacttgtc
     9241 agcgcccttt ggcccaataa gcttgccaat ttcttcaaaa acagcaatag agcgctgaat
     9301 attttcgtta ctctcttttc catttacttt tggaatgcta tcccgctcaa tatcaacatc
     9361 taaaccatca agattatatt tataaacgta ttcatctaca atagcctttg ccaaggcctt
     9421 atttccctct ggagtatttg ggtatttttg cgtatcttca gcaataccac tatgatcacc
     9481 gcctgcaagg aaccgccatg gaatggtacg aatcacacgt gttccctgct tgttcagcgt
     9541 tggcacatgc ttggtcgcca attcttgcca gaaaaagcta taatccttgg tccaatcatg
     9601 gaaaacaaag gctaagtcaa cctccttagg caattctccc atagaattaa ccttatcctt
     9661 ttcagccgga tctgatgttt tatcatgcca agtcctaaaa tagccaccat aaagaggccc
     9721 ctttaaaggc ttcatggcta ttttttcagg aaccttcatt tctgcaagaa cctttgcctg
     9781 cttatctgcc tgctgtgcct tggataaaat atcctttagc ttttcaggta cttctcctgc
     9841 ctttgataac ccctccttaa attctttttt actgttttcc gacaggtaat gtaggtcatc
     9901 aatagcagag actgatggac tagtttgcac aaccttatcc tctgccttga cccttatgag
     9961 tgaatcatgt tgggcagcta atatagccac cattaacgct gcagcacaaa cacatttcag
    10021 tgttttcttg actaacacct gtttttccat tgggacactc ctttattttg ataccaaaga
    10081 atggcaaatc tttgctgaac caaaaatgta agcgcattct ctgcgttcgt ctaaagtata
    10141 gtagacctca tgatcaaaag caatgcacaa agtataggta aaataaaaga aacttaaggt
    10201 cttttaattt ctgtaatttt atggtgaata ttttaatctt acatgtaaaa agagatgaaa
    10261 tcatcaactc ttttcaaatt attttacaag gatcactgga ctgccaacag tcaccttacc
    10321 ttgtgccaaa atctgaacag catgaacatc tgcgctattg gtgacaagca gcatggttgt
    10381 agtatcaagg cccgcctgct gaatccttgc aatatcaaag cttccaagag catcaccagc
    10441 cttgaccatc tgaccaacct taacaaaggt ttcaaagccc tcacctgcca ttgaaacggt
    10501 atcaatacca atatgcagta ggatttctgc tcccttatct gatttgatga cgtaagcatg
    10561 acctgtctca agggcagcct ctaccctgcc atctaccggt gagcagagaa tgcgcccttc
    10621 aggcttgatg gcaacgcctt ggcccatgct tcctgacgaa aagacaggat cagcaaccga
    10681 tgacaaatca atcaactccc ctgcaactgg actaagcagc tcctcagcag cagaggcttt
    10741 ttgcgcaggc tctgatttta cttgggtagc cggtgcttct tggtcactct tgtccttgaa
    10801 tccccaaata taggcaatca caaaagctag accaagccca accaacagtg tcacaaggta
    10861 ctgtagtagc tgaccattaa gatacagcag tgcaccaggc aaaaccgtaa tcccaaagcc
    10921 ggtaccagca atgccaagaa tccctgcaac ccagccacca gctgcgcccc cgataagtcc
    10981 tgagacaaat acctttgggt agcggagatt aaccccaaag atagccggct cagtaatccc
    11041 taaaagagct gacagagctg atggaaaggc taaacccttt aattttgcag acttggtttt
    11101 aacagcaacc gctagagttg ctcctgcttg ggcggccgta gcagctgtca aataagcgtt
    11161 aaagggatcc tttcctgtat tggcaactag ctgcgcctcc aagaaattga aaatatgatg
    11221 gatacctgtc acaacaatca gctgctgaac acccccaata acaaggccgg caatcccaaa
    11281 aggcagacct aaaactgctt gtgtccctgc aagaacaagg ttttccaagg agtgaaagat
    11341 aggcccaatc acaaagagcc ccaaggcact cataatagca aaggtcaaaa acggcgttgc
    11401 caacaaatca agcgcatcag gcacccgctt atgcagccac ttttccagct tggcaccaac
    11461 cagaccaaca aagaaggctg gcaataccgt accttgataa ccaacaactg gaacaaaacc
    11521 aaagaaagtt aagggcttaa catcacctcc tgaggctacc acccaagcat ttggcaactc
    11581 attagagacg agcatcaagc caaggacaat cccaatgata gggttgccac caaataccct
    11641 aaaggctgac caagcaacca aggccggcag gtagacaaag gccgtatctg ttaaaatccg
    11701 agtgtacatg aggaaattgt cgccatagtc atgaatacca aagaactcca taacagccgg
    11761 ctgcgtcaag agaccccgta cacccataaa cagccctatc gccacaatag caggaatgat
    11821 cggaacaaag acatcaccaa aggtacgaat agcccgctga aaggcatttc cagacttgac
    11881 cacttgctcc ttttgctcac ctgccaaagc agctggaagc cctagagcta caacctcatc
    11941 ataaatgcta ttaaccgtac ctgtcccaaa aatcagctga tattggcctg agttgaaaaa
    12001 agcaccctta accttatcaa tagcctctgc tttttcctta ttgatcttac cctcgtcatg
    12061 aaccataacc cgcagccgcg tcgcacaatg agccacactt ctgacatttt cacgaccgcc
    12121 taaggcctcg ataacctctt ttgcaatctg atgattatcc ataccgatag catctccttt
    12181 tttgtctgtt atagtctatc gaaatagctt ttcttgagcc tatccaatat tggcggacct
    12241 accctactgt ccgactcaag atggtctttc aatttactat tgtgaatccg cttcacttct
    12301 tgctatcatt ttaacacgaa tattttttat gtcaagcgtt tgacatatat tttgtttaaa
    12361 ataattaaaa aagttgattt ttagagagaa aacgtttatc atatgaataa aaatgaccaa
    12421 tacctaagga gacctgacat ggatttacca agatctattc gctaccgacc atatcaagaa
    12481 tggagcaagg aagcctatca agcaatccaa caaaaggtgg cccagtcttt atggcgcagc
    12541 catttccata tagaagctcg tacaggtctc ctcaatgacc caaatggctt ttcttatttt
    12601 gctggcagct ttcagctttt ctatcaaaat tggccctttg gagcagctca tggtctaaag
    12661 caatgggtac acaccacatc aactgacttg gtgcatttta cagaaaccaa aactcggttg
    12721 ctgccggatc atcaaaacga tagtcatggc gcttattccg gctctgctta tcctattggt
    12781 gacaaactct ttttatgcta tacaggaaat gtccgcagca aggattgggt acgccaccca
    12841 ctacaaatag gtgcctggat ggaccaatca ggccacatca caaaatgtga gcaggtgctc
    12901 attgacaagc cagatgatgt cacagagcat tttcgtgacc cccagctctt tacctaccaa
    12961 gatcagcttt atgccatcat tggtgcacag aatttgcaac aacaaggtat cattaagctc
    13021 tacaaggcta acaacaatga tgtcaccagc tggcaatttg ttgctgactt ggattttgat
    13081 gactcaggca ccgcatacat gattgaatgc cctaatttgg ttttcattga agataagcct
    13141 gtgcttatct tctgccctca ggggcttgcc aaatcagagc ttgattacca aaacatttat
    13201 cccaatacct ataaggtatt tcagaccttt gatcctaaaa gacgcaagct ccttggggga
    13261 ggtccaatcc aaaaccttga ttttggattt gaagcttatg cgacacaggc ctttaatagc
    13321 cctgatggta gggtactggc agtttcttgg attggcctgc cggacatcga ctacccaacc
    13381 gataaatatg cctaccaggg agcgcttagt ctagtcaagg aattacgact caaaaatgga
    13441 aggctacacc aagcaccagt ccctgctctc agtaagctac gagacaaagc ccagcccttt
    13501 cagaacaaaa aaaacagctc aaactgctat gagctggctt tgaccattga agcacagcaa
    13561 gcaacagagc ttttgctctt tgccgataca cagcacaagg ggctgaaact gaccgttgac
    13621 acctgcaaag gacagctaac aattgatcgc agcaaggcag gcgcccagta tgcccaggaa
    13681 tttggagcaa agcggtcttg ccaaattcct gtcaatcgtg ctacacttaa tatctacgta
    13741 gacaagtcta ttctagagat ttttgtcaac caaggcgaag cagtcctcac gagtcgtgtc
    13801 tttccaaatg aggggcagtc tggcattgag ctgctaaagg gccaggtgag tggctactat
    13861 tatgaaatga ggtactagac aagtggtcgc aaaattaaca gatgttgcag cattagctgg
    13921 tgttagccca acaacagtct cacgtgtgat taacaaaaaa ggctatctgt cccagaaaac
    13981 cattgataag gtgaacaaag ccatgcgaga gcttggctac aagccaaata acctcgcacg
    14041 aagcctgcag ggcaaatccc ctcagctcat tgggctgatc tttcctaaca ttagtaatat
    14101 tttttacgcg gaattgattg agcatttaga aatcgagctc tttaagcaag gttataaagc
    14161 catcatttgc aacagtgaaa acaacccgat caaagaacga gattatttag aaatgctagc
    14221 tgccaatcag gttgacggca ttatctcatc aagccataac ctaggtattg atgattatga
    14281 gcgtgtcgag gcacccatcg tcgcctttga tagaaacctc gctcctcata tccccatcat
    14341 atcctctgat aattttgaag gagggaaatt ggccgcaaaa accctgcaaa agcatggctg
    14401 ccaaaaaatg atcatgatta caggaaatga tcattctgac tccccaacag gtcttagaca
    14461 gctaggcttt aattaccagc tcaaaaaagg cgctgatatt ataaaactgc caaatgatct
    14521 ttccagtatt cgccgcgaaa tggaaatcaa gtctattttg gcgacaagaa ggcctgacgg
    14581 catttttgct tctgatgatt tgacagctat cctcatcatg aaggttgctg gccagcttgg
    14641 catagcaatt ccagataacc tgaagcttat cggctatgac ggtacggctt ttattgagca
    14701 ttatttccca cagctcacca ccatcaagca gccgatcaag gagattgcca gcttaaccgt
    14761 agaagtatta ctgaaaaaaa taggtaacga aaaaaccagc aaggactatg tcttaccgat
    14821 caccctgctt cccggaggca gtctctaaga gcaatagctc ttcttctgtg attagcggct
    14881 ttcccctagc ttctccctta cttggggcac taaagtaaaa accaaagcac gaggtgggaa
    14941 accctagacc accaggatac acccagatag gtccccaaaa gaaagcttga taagcctgac
    15001 cacctaacaa aacctgcaca caaggaaagc ttcctcaagc tgtcctttgt acccttttcc
    15061 taacaatgcc accaaaaaca catgtaacag caagtgacag actcccccta tagcaaacag
    15121 tgacccaaca aaccatcact agaagctata aggggagctt ttctatgcct aacaaaaatc
    15181 taaaatcaat aacagaaaaa cctaaagcag ttcatgcgca catactacct atctgctact
    15241 attgctctaa aagcaaccgg ctgatcggac aggttggtaa tggtgatact atagtcatga
    15301 tcttctgtca cactatattt tctcttcccc ttcaagggaa cgatgaggcc atctccatca
    15361 atagtagctc ccttgtgtcc agcttctaca ataactacac cattatcctt agtggaatcg
    15421 tatttttcaa taacctgttc tgttatagaa taccgatatc ctatcttact aagatagctg
    15481 tctgtccgtc tataaatata ttcagaccat atatcacgac cttctagctt cagtagcact
    15541 ttttcgtcgc tttctaggta taggtcagag gaatattcta tttgttcata ctttggtctc
    15601 accgcaagct ctatactctc atttggcctt agatattctt ttccttgaaa aaaatagtaa
    15661 agctcatagc gtttggagaa gatgaaaaca cctaccagca acatcattaa taacaggatt
    15721 tttcgcttca ttttgacttc ttccttttca tataaccatc tatacctgct tggatcattt
    15781 gagtatcacc ctcattgtct ccatagtgac ctgatgataa gttctttaac cactttggta
    15841 tatccttatc agaaaagacc tgggcaatct cagccgccgt ttttaaataa gtccctgaag
    15901 catctaaaaa gcctgtacca acataaccat agaggtagtt gccagcatag tcgcctggca
    15961 attctgattc ccactgtctt gaccagacag aatagttatg gccatgatag gtccttgact
    16021 tcaaatccaa gggctgaccc gtattgacaa ggtcataaaa ttgtttgttg tcaagtattg
    16081 cagcacttaa ttgacttcca gctacctgtg aaaggtaggg agcattgaca ttcactgata
    16141 ggatatcatc tcccatcttg ttgacaatca aacgaaaatt aatacccgac gattgtaatt
    16201 ttttccctag gtcttcctca atttcctttg catatttatt atttttaagg tctcactctc
    16261 catcataatt gcttctcgcc ttccaatagt catcaaaggc tgttttattg agaaaataga
    16321 ggtaatcctc ataggcagct acaagtcgct ctgatttttg tagtggcctt tcagagctgc
    16381 ttttgatggt tttaatggtc tgagtcagta tgttgtgata atggttttga gtgtactttg
    16441 aggcattgac agggctaatc ttttgattct tcaggctagt cacccagctc atatctaggc
    16501 cagcagtcga gtagctgccg tcgctgctca tgaagacctg actgagctgt gttgcgccct
    16561 gaatggctaa ccgcaaaata actaagctgt ccctaaagca gtctgaggtt tgagttagaa
    16621 accattcaag gctttccaat ttggtcgtaa catctcgaat ccctatttcc agctggtttt
    16681 tggcatggta tagtgtagag gtatcagacc aaagggtgcc atagtctccg gttaaaagac
    16741 tactgacctg cttcataaac gattcgtttt catcaatctg tgcttggatc acttgcactt
    16801 gccgttctct tagcctcttc agctcggtta agtgatcacg atccagggtt ccgtatctgg
    16861 caatctgagc atctgccctt tgataggtgg tcaactccac ttggatagca tcaatcgctg
    16921 cttgtagctt tttgatagag ggaatgatga tcgctgtaaa aagtccccta cctgctgtat
    16981 aggctgctcc ctgtagctct cccgaatcca gactagcaat gagatggtcg caaccacttg
    17041 ataacctgtc cgttatttca ttggctattt ggatattgtt tgtcatggct tgaatcaagg
    17101 cctttgactc tgctgcactg taggtcactc ccatcgtaaa cggctccttt caccgataag
    17161 ctcttctttg tccctctcta gtctacgacg aacccccatc gtatagattg acacgtgatc
    17221 cagatgctca tcaacatagc gatccatttg tctgatcaag tggtcattgg cctcttgctc
    17281 tgcgtacttt ccagcttagt cctcaggcat atggttcaat agggactcaa gggcaaaaga
    17341 gaggtgctga cagtctgctt gaatctccga gactgcttgt tcatgccgtc gtttcatcga
    17401 caaaagatcc tcctctagcc actccagctc attgatctgt cgggttaggg caagaaattt
    17461 ttcttcagat tcttctttga tcatgactta ttcccctatc ttgttgcttc ctctaggtct
    17521 cttttctcta atttggccgc aagctgagga aatttattag cctgaataag gactgcctga
    17581 ctaaagtcgc tgacagcctg cagcagttga ttagagacct gacgtccctt ttccatacct
    17641 gcaataccct tggtcacact aaatgcaacg gactgttggt gaaccctact ggtgtctaca
    17701 cctaccaatt cactaatagc agcagaagca gccacagggc ttgatgtaat ggtatcactc
    17761 atacaatttc tcctttataa cccttatgtc ttttattata tcacaggata atagccattg
    17821 tgcttatagc tcttacctaa ataatagcaa ctgat
//
LOCUS       DARYNN010000042        17305 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.042, whole genome shotgun sequence.
ACCESSION   DARYNN010000042 DARYNN010000000
VERSION     DARYNN010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17305)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17305)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17305
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.042"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(152..742)
                     /locus_tag="TVB59_001496"
     CDS             complement(152..742)
                     /locus_tag="TVB59_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010377.1"
                     /translation="MKKVKQLIIAMIASLLLIANTVPSIVYASEVTKIQQEEKVIEEK
                     LSQPLEISKSELDTLIQEKKALYPNLTEQEMREIAYKAMSPYTFRASVWDGQGVTLDE
                     FAWAFDVIVGGLISGYATIGKYVAKHGVAAARAVLSRAAKAAAQRLGVLTGFISGLLR
                     AAFSVINIYYNVGYALAQYVDARDYHPNNGRINAWA"
     gene            1265..3307
                     /locus_tag="TVB59_001497"
     CDS             1265..3307
                     /locus_tag="TVB59_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEL1010378.1"
                     /translation="MVDSKAVVILMTLMTYQDLSLYELSVKTKFTIREIKDRIDELNE
                     FLAQHELSELDATRSGYRISQQLKAESDHLFTLINAEQVYLSQAERINLIYLYTFCRR
                     DFVSNSHYQDFLKVSKNTALTDIKALRQKLADVDLELKYTRASGYILVGDEINKHRLA
                     LVMIATLLKSPIGLWALDYILASWHYQVSFEALEKRVSHFYQTFQMSPILDRLQVCLY
                     AVIFILCRYQRRVDRVKQRQVVVSEQLDQLTALLVAEIMQQLSLKYQLFEADEAYFQL
                     LLAGCFEGEGTVGDDFFESLTVAIVDQMQGVALLSFSQADQLKENLKRHLIPAYYRLR
                     YGLPSDNDYTLRIKDSYSELFDLVKQSLEPLAKELGSPIPDSEIAYFVLHFGGYLKQQ
                     GRDFHRQAYQAVIVCPNGVSSSLMIKEHLKLLFPDIAFRGLSRLDQLGQLDKSGYDLV
                     FSTIRLETDKPFYLVPMIMTDEQAFQLVSLVNRDFPDIGYRLEVEELLHLISSYAVIH
                     QKEKLRFALQQYLRQGVKRKDIRPVLQDLITKKTYQSTSEQLGWREAIYLAAQPLLES
                     GQIQASYPEAMIAKVEEFGTFINLGKGIAIPHARPEDGVNQVGMSMLVLEHPIYLLDD
                     PKQEIRLLICIAAIDNETHLKALSRLTTILRDNEQVKALLASKSFEDIKTIIAEEA"
     gene            3309..3596
                     /locus_tag="TVB59_001498"
     CDS             3309..3596
                     /locus_tag="TVB59_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1010379.1"
                     /translation="MALRIGTACGSGLGSSFMVQMNIESVLKDLGVTGVEVEHYDLGG
                     ADPTAADVWIVGRDLADSAEHLGDVRILNSIIDMDELTSLVKAICQEKGLV"
     gene            3609..4952
                     /locus_tag="TVB59_001499"
     CDS             3609..4952
                     /locus_tag="TVB59_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEL1010380.1"
                     /translation="MTFLLDIVSTPAILVALIAIVGLLLQKKPAPDIVKGGIKTFVGF
                     LVVSGGAGIVQGSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATALIMFTGMI
                     FNILIARFTRFKYIFLTGHHTLYMACMIAVIMSVAGLTSVSLIVFGGLALGIIMSVSP
                     ALVQRYMIQLTGNDKVALGHFSSLGYWLSGFVGGLVGDKTKSTEDIDFPKSLAFLRDS
                     TVSITLSMAIIYLIVAIFAGPTWISKELSSGTHGLVFALQLAGQFAAGVFVILAGVRL
                     ILGEIVPAFKGISEKLVPHSKPALDCPIAYPYAPNAVLIGFVSSFVGGLVSMAVMIVS
                     GTTVILPGVVPHFFCGATAGVIGNASGGVRGATVGAFLQGVLISYLPIFLMPVLGGLG
                     FEGSTFSDADFGLSGILLGTLNSIGGVTAIVIGIFVILAGLVGLSVVGKSVAKEE"
     gene            4955..5812
                     /locus_tag="TVB59_001500"
     CDS             4955..5812
                     /locus_tag="TVB59_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEL1010381.1"
                     /translation="MVLSDEPLTDVKRFAAEIRLNTLETLNHLGFGHYGGSLSIVELL
                     AVLYGEIMPMTPELFVQSDRDYLVLSKGHAGPALYSTLYLKGFFDKAFLQSLNTNGTS
                     LPSHPDRLLTPGIDMTTGSLGQGISVATGIAYAQALEQSPHYTYAIVGDGELNEGQCW
                     EAIQLAAHQQLSHFIVFVDDNKKQLDGTTEAICRPGDFVEKFTAFGFESLRVDGRDVQ
                     AIFEAIRALQASSSHKPKCIVLDTVKGQGVSQLESMAANHHLRPTAAEKEMLAAAVRK
                     LRASLEVTR"
     gene            5809..6741
                     /locus_tag="TVB59_001501"
     CDS             5809..6741
                     /locus_tag="TVB59_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEL1010382.1"
                     /translation="MTRASQEMRHVYRDFLIAANQEHPEVVVLEADLSSSMATNHLDQ
                     VFGKRYINVGIMEAEMVGLAAGLAIKGYKPYLHTFGPFASRRVFDQLFLSLAYAQLGA
                     TVIGSDAGVSAEMNGGTHMPFEDLGLLRLIPRAIVYEVSDDVQFKAVLKETLSLDGLK
                     YIRTIRKKPEAIYQGHEDFSNGYCLLRQGKDLVLACSGIMVKRCLEVADKMAEQGYSI
                     GVIDVFRVKPLADELKGLLTGSPVLTVENHNRIGGLGSAICELLAQESNTPVYRMGVD
                     ERFGQVGQMDYLLEEYQLTPAAIEQQVLRILAAD"
     gene            7293..9188
                     /locus_tag="TVB59_001502"
     CDS             7293..9188
                     /locus_tag="TVB59_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase"
                     /protein_id="HEL1010383.1"
                     /translation="MTTYQEDFYQAVNGQWAETAVIPDDKPRTGGFSDLADEIEDLML
                     TTTDAWLAGEHVPNDAILENFVKFHRLVADYDKRDQVGVAPALDLIEEYKALGSFAEF
                     ASKVADYELNGKPNQFPFSVAPDFMNAQLNVLWAEAPGLILPDTTYYAKDNDKGKELL
                     AIWRGMQEELLPKFGFSHEEVKDLLDKVITLDKQLADYVLSREEYSEYAKLYHPYDWA
                     EFTKLVPELPLDNIFTVILGEVPDKVVVPEERFWTEFAADYYSEKNWELLKAWLVLTA
                     AGAYHAYLTDEIRVLSGVYSRALSGTPQAMDKKKAAYYLAQGPFNQALGLWYAGEKFS
                     PEAKADVEHKVAKMIEVYKSRLETADWLAPATREKAITKLNVITPHIGYPEKLPETYA
                     KKVIDDKLSLVENAQNLAKISIAHSWSKWNKPVDRSEWHMPANMVNAYYDPQQNQIVF
                     PAAILQAPFYSLSQSSSANYGGIGAVIAHEISHAFDTNGASFDEHGSLKNWWTDEDYA
                     AFKERTDKIVEQFDGLDSYGAKVNGKLTVSENVADLGGVACALEAAQSEPDFSARDFF
                     INFATIWRMKAREEFMQMMASIDVHAPGQWRTNVTLTNFDEFHQEFNIKEGDPMWRAP
                     EDRVIIW"
     gene            complement(9388..10428)
                     /locus_tag="TVB59_001503"
     CDS             complement(9388..10428)
                     /locus_tag="TVB59_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEL1010384.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDMEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVVEVNAETDFVAKNAQFVELVNATAKAIAE
                     GKPANNDEALALIMPSGETLADAYVNATATIGEKISFRRFALVEKTDDQHFGAYQHNG
                     GRIGVITVVEGGDEALAKQVSMHVAAMKPTVLSYTELDPQFIKDELAQLNHAIELDNE
                     SRAMVNKPALPFLKYGSKAQLSADVIAQAEEDIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLDSVNAKAISFARFEVGEGIEKKANDFES
                     EVAATMAAALNN"
     gene            complement(10596..11366)
                     /gene="rpsB"
                     /locus_tag="TVB59_001504"
     CDS             complement(10596..11366)
                     /gene="rpsB"
                     /locus_tag="TVB59_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEL1010385.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKLADQAYEFVRDAAANDAVILFVGTKKQAAEAVADEATRAGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEEGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNADPDDIDVIIPANDDAIRAVKLITAKLA
                     DAVIEGRQGEDAEVAFEADTQAESIEEIVEVVEGSNEA"
     gene            complement(11827..13359)
                     /gene="ahpF"
                     /locus_tag="TVB59_001505"
     CDS             complement(11827..13359)
                     /gene="ahpF"
                     /locus_tag="TVB59_001505"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HEL1010386.1"
                     /translation="MALSPDIKEQLAQYLNLLESDLVLQAYLGSDDSSQKVKDFIEEI
                     AAMSDRITVEETTLTRQPSFKITQKGQDSGVIFAGLPLGHEFASFILALLQVSGRAPK
                     IEQDIIDRIRAIDRPLSFETYVSLTCHNCPDVVQALNIMAVLNKNISHTMVEGGMFQE
                     EVKAKGIMSVPTVFLNGEEFTSGRATIEQLLEQIAGPLSKEAFADKGVYDVLVIGGGP
                     AGNSAAIYAARKGLNTGLLAETFGGQVMETVGIENMIGTLYTEGPKLMAQVEEHTKSY
                     DVDIIKAQLATSIEKKDLVEVTLANGAVLKAKTAILALGAKWRSINVPGENEFKNKGV
                     TYCPHCDGPLFEDKNVAVIGGGNSGLEAALDLAGLAKHVYVLEFLPELKADKVLQDRA
                     AKTDNMTILKNVATKDIVGDDHVTGLNYIERDSNQEKHLDLEGVFVQIGLVPNTAWLK
                     DSGISLTDRGEIIVDKYGSTNIPGIFAAGDCTDSAYKQIIISMGSGATAAIGAFDYLI
                     RQ"
     gene            complement(13380..13940)
                     /gene="ahpC"
                     /locus_tag="TVB59_001506"
     CDS             complement(13380..13940)
                     /gene="ahpC"
                     /locus_tag="TVB59_001506"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002273221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HEL1010387.1"
                     /translation="MSLVGKEIAEFSAQAFHNGKFITVTNEDLKGKWAVVCFYPADFS
                     FVCPTELGDLQEQYEILKSLGVEVYSVSTDTHFVHKAWHDDSDVVGTITYPMIGDPSH
                     AISQAFDVLGEDGLAQRGTFIIDPDGVIQMMEINADGIGRDASSLIDKIRAAQYVRKH
                     PGEVCPAKWKEGAETLTPSLDLVGKI"
     gene            14288..14358
                     /locus_tag="TVB59_001507"
     tRNA            14288..14358
                     /locus_tag="TVB59_001507"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:14320..14322,aa:Cys,seq:gca)
     gene            complement(14465..15532)
                     /locus_tag="TVB59_001508"
     CDS             complement(14465..15532)
                     /locus_tag="TVB59_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEL1010388.1"
                     /translation="MAKFRKRGDKWSYRIYYTDSQGNKREKSKGGFKTKALASAAAIK
                     VEAELNKDIDDISLYDFCKEWAKIYKRPHVVDKTWETYTKNLKHIKKYFGDIKLNNVT
                     HTFYQKTINEFAKKYAQETLEKLHYQIKGAVNVAVRDGLIKTNFAEGAIVKSQKEARA
                     KEFDFLEEDEYLNLIKVTSEKYQYVSYFTLYIIAVTGLRFAEATGITWSDIDFEKGFI
                     DINKSFDYSKTQEFKETKNEQSKRQIPIDQQTIKLLRAFKENYYNENKLNRVLYGASN
                     SLCNRLVKKIVGRPVRNHSLRHTYASFLILKGVDLISISQLLGHENLNITLKVYAHQL
                     DKLKEKNNQAIKDIFGNLTDF"
     gene            complement(15659..15934)
                     /locus_tag="TVB59_001509"
     CDS             complement(15659..15934)
                     /locus_tag="TVB59_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEL1010389.1"
                     /translation="MRYKVLFTKKAKKQLKKLDRSTAKQLYQWIMTNLDGTDNPRRYG
                     KALQANRTGEWRYRLGNYRILAEIIDDEVVIEVFKIEHRSSVYKIKR"
     gene            complement(15924..16142)
                     /locus_tag="TVB59_001510"
     CDS             complement(15924..16142)
                     /locus_tag="TVB59_001510"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEL1010390.1"
                     /translation="MIAMTLNLEKDDAYIADYIKENNIDTSNLTVDQFLEIIEDAKDL
                     YELRKAKAEDDGTRFSMEDVAKELGFAL"
     gene            complement(16158..16679)
                     /locus_tag="TVB59_001511"
                     /pseudo
     CDS             complement(16158..16679)
                     /locus_tag="TVB59_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059208.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            17068..17274
                     /locus_tag="TVB59_001512"
     CDS             17068..17274
                     /locus_tag="TVB59_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1010391.1"
                     /translation="MLNIDKVRKEKGVAIVDMADFLGVRAQTVSDKLRGTYDFKFTEA
                     LALQQKFFPEYDLEYLFNKAVDTA"
BASE COUNT         4730 a         3357 c         3732 g         5486 t
ORIGIN      
        1 tcagtcttta ttttttgtta tgtaaaaagt ataggtggtt atggccgaat agaaaactag
       61 ttttggagta aatgataagg ataagcgatt gaaacaatat gctattgctg tataaactga
      121 cattacaata ataaaataac aaatatagtt cttaagccca cgcatttata cgaccgttat
      181 ttgggtgata atctcgagca tcgacatatt gtgctagggc atatccgaca ttatagtaaa
      241 tgtttattac tgagaatgca gctctaagta aaccggaaat aaatccggtt agtacaccaa
      301 gtcgttgagc tgcagctttt gcagctcggc taagtacagc tcgagcggca gctactccat
      361 gtttggcaac gtactttccg atggttgcat atccactaat taacccgcct acaataacat
      421 caaaagccca agcgaattca tctaaggtta ctccttgccc gtcccataca ctagctctaa
      481 aagtgtatgg actcatggct ttatacgcaa tttcacgcat ttcttgttct gttaaatttg
      541 gataaagagc ttttttctct tggattaatg tatctaactc actttttgaa atttctagag
      601 gttgtgataa tttttcttca attacttttt cttcctgttg aattttagtc acttcactag
      661 catatacaat ggaaggtaca gtgttagcaa tgagtaataa ggacgctatc attgcgatga
      721 tcaattgttt tacttttttc attttgaatt tcctttctga aaacgatggt gatctactaa
      781 gggttaatta gctttactcc tttctaacca agatggtagt tatttgtcat ttaataagat
      841 atcttatagt ttcattatat tattaaaata ataaaacaca agtctttttt ggtaaccgtt
      901 ttcgtggtat aataaaagat taccagttaa ctattaagtc tgtaatcttg ttttaggctt
      961 atatctagag ttatcacatg ctgatgaggt caatcagttt ttttgattat ttggaacatt
     1021 tttgacggtt attactccaa agagctttag ctttggcttg gacttaggaa atcatgggga
     1081 caattgctta gcggcagaga tgggcttgtt tgctctttat tgatagttag gaggagctgg
     1141 tagcctgttt agattggcat cttgagccca agggctgttg atgatgttgg ataagaaatt
     1201 gtgcccaatg gggactagtt tattgtaacc gttttcgata gaatgaattt agaaaggaaa
     1261 tcaaatggtt gatagcaaag cagttgtcat tttgatgacg ttgatgactt atcaagactt
     1321 atcactttac gagctgagtg ttaagacaaa attcaccatt agagagatta aggaccgtat
     1381 tgatgagctg aatgagtttt tggctcagca tgagctctca gagctagatg caacaaggtc
     1441 tggctatcgg atcagtcagc agcttaaggc tgagtcagat catttgttta cgttgattaa
     1501 tgctgagcag gtttatcttt ctcaggcaga gcggatcaat cttatctatc tgtatacctt
     1561 ttgccgcagg gattttgttt caaatagtca ttatcaggac tttttaaagg tcagcaagaa
     1621 cacagccttg acagatatta aggccttgcg gcagaagctg gcagatgttg acttggaatt
     1681 aaagtatacc agagcaagcg gctatatctt agttggtgat gagattaata agcaccggtt
     1741 ggctttagta atgattgcta ctttgcttaa atctcctatt ggcttgtggg ccttggacta
     1801 tattttggct tcttggcact atcaggtgtc gtttgaagcg cttgaaaaac gtgtgagcca
     1861 tttttatcag acctttcaga tgtctccgat ccttgatcgt ctgcaggtct gtttgtacgc
     1921 tgtcatcttt attttatgtc gttaccaaag acgggttgat agggtcaagc aaagacaggt
     1981 agtggtttct gagcagctgg atcagctaac ggcccttttg gtggcagaaa taatgcagca
     2041 attgtctctt aagtatcagc tatttgaagc tgatgaggcc tattttcaat tgctgttagc
     2101 gggctgcttt gagggtgagg gtactgttgg tgatgatttc tttgaatcac taaccgttgc
     2161 gattgttgat caaatgcagg gggttgcttt actaagcttt agtcaggcag atcagctcaa
     2221 ggagaatttg aaaaggcatt tgattccagc ctattaccgt ttgcgctatg gtttgccaag
     2281 tgataatgat tataccttgc ggattaagga tagttattct gagctttttg acttggtaaa
     2341 gcagtctctg gagcctttag ccaaggagct gggtagtcct ataccagata gtgaaattgc
     2401 ttattttgtt cttcattttg gaggctattt aaagcagcag ggaagagatt ttcatcgtca
     2461 agcctatcag gctgtgattg tctgtcctaa tggtgttagt tcttctttaa tgatcaagga
     2521 gcatttaaag cttttatttc ctgatattgc ttttcggggg ctttcaaggc ttgatcagct
     2581 tgggcaatta gataagagcg gctatgattt ggttttttca acgatacgat tagagactga
     2641 taagcccttt tatttagtcc ctatgataat gactgatgag caggcttttc agctggtcag
     2701 cttggttaat cgtgattttc cagatattgg ctatcggcta gaggttgaag agctgctcca
     2761 tcttatcagc tcatatgcgg tcattcatca aaaagaaaag ctgcgctttg ctttgcagca
     2821 atatttaaga caaggtgtga aaagaaagga tattcgacca gtgttacaag acttaattac
     2881 caagaaaacc tatcaatcaa cctcagagca attggggtgg agagaggcta tttatttggc
     2941 ggctcagccc ttgttagaga gtgggcagat tcaagcgagc tacccggagg ctatgattgc
     3001 taaggttgag gagtttggta cttttattaa tctaggtaag gggattgcta tcccacatgc
     3061 gaggccagag gatggtgtga atcaggtagg tatgtcgatg cttgttttag agcacccgat
     3121 ttatttgtta gatgatccta agcaggagat tcgtttgtta atttgtattg ctgctattga
     3181 taatgaaaca catctaaagg ccctgtctcg gctgacgacc attttaagag acaatgagca
     3241 ggtcaaggct ttacttgcgt ctaaatcatt tgaggatatt aaaactatta ttgcagagga
     3301 ggcataaaat ggcattaaga attggtacag cctgtggttc aggcttaggg tctagcttta
     3361 tggttcagat gaatatcgaa tccgtattaa aggacttggg agtaaccggt gttgaggtgg
     3421 agcattatga tcttggtggc gcggatccca cagcggcaga tgtgtggatt gttgggcgtg
     3481 atttggcaga ctcggcagag catctgggag atgtgaggat tttaaatagt atcattgata
     3541 tggacgaatt gactagtctg gtaaaggcta tttgccagga aaaggggctt gtttagaagg
     3601 aggataagat gacattttta cttgatattg ttagcacacc agctattttg gttgccttga
     3661 ttgctattgt tggtctctta cttcaaaaaa agcctgctcc tgacattgtt aagggaggca
     3721 ttaagacctt tgttgggttt ttagtggttt caggtggtgc aggtatcgtg caaggctcac
     3781 tcaacccttt tggaacgatg tttgagcatg cctttcatct gtctggtgtt gtgccaaata
     3841 atgaggctat tgttgcagtt gctttgacga cctatgggtc agcgacagct ctgattatgt
     3901 ttacaggaat gatctttaat attttgattg ctcgctttac ccgatttaag tatatcttct
     3961 tgacagggca tcacacactt tacatggcct gtatgattgc tgtgattatg tctgttgcag
     4021 gcttgacgtc agtgtccttg attgtgtttg gtgggctggc cttagggatt atcatgagtg
     4081 tttcaccggc tcttgtgcaa cggtatatga tccagctgac tggtaacgat aaggtcgctt
     4141 tggggcattt tagctctctt ggttattggt taagcggttt tgtaggaggt cttgttggag
     4201 acaaaaccaa gtcaacagag gacattgatt ttccaaagag ccttgctttt ttgcgtgata
     4261 gtacagtaag cattacctta tcaatggcaa tcatttattt gattgtagct atttttgctg
     4321 gtcctacttg gattagtaag gaattatcct ctggcacaca tggcttggtc tttgccttgc
     4381 agttggcagg acagtttgct gcaggcgtct ttgtgatttt agctggtgtt cgtttgattc
     4441 tgggtgaaat tgttccagcc ttcaagggca tttctgaaaa attagtgcca cattctaagc
     4501 cggccttgga ttgcccgatt gcctatcctt atgcccccaa tgcagtgctg attggctttg
     4561 tttctagctt tgttggtggc cttgtgagca tggctgtgat gatcgtaagt ggaacgacag
     4621 tgattttacc tggcgttgtg cctcatttct tctgtggtgc cacagctggt gttattggga
     4681 atgcttctgg aggtgtgcgc ggtgcaactg tgggagcctt tttacagggt gttcttatta
     4741 gctatcttcc gattttcttg atgcctgttt taggcggctt gggctttgag ggctcaacct
     4801 tctcagatgc cgattttggc ttatcaggta ttttactagg aacacttaac agcataggtg
     4861 gtgtgacagc tattgtgatt ggtatttttg tgatattagc tggacttgtt gggctttctg
     4921 ttgttggaaa atcagtagct aaggaggaat aagcatggtt ttgagtgatg agcctctaac
     4981 agatgtgaag cgattcgcag cagagattcg tctaaatacc ttggagactc ttaatcatct
     5041 tggctttggt cattatggcg gtagcttgtc tattgtagaa ttgctggctg tgctttatgg
     5101 agaaatcatg cccatgacac cagagctctt tgtccagtca gatagagatt atctggtgtt
     5161 atcaaaggga catgcgggtc ctgccctcta tagcactctc tacttaaagg ggttttttga
     5221 taaggccttt ttacagtctc ttaataccaa tggaacaagt ctgccctcgc acccagatcg
     5281 tctgttaacg cctggtattg acatgacgac aggctctctt ggtcagggaa ttagcgtagc
     5341 aacgggcatt gcctatgctc aagcgcttga gcagtcacca cattatacct atgcaatcgt
     5401 tggtgatggg gaattaaacg agggccaatg ctgggaggct atccagcttg cggcacacca
     5461 gcagctaagt catttcattg tctttgttga tgacaataag aagcaattag atggaacaac
     5521 cgaggcaatc tgtcgtccag gtgattttgt tgaaaagttt acggcatttg gctttgaaag
     5581 cttacgtgta gatggtaggg atgttcaggc tatttttgaa gccatcaggg ctttgcaggc
     5641 gtcatcaagt cataagccca agtgtatcgt cttagatacc gtcaagggtc agggtgttag
     5701 ccagctagag tcaatggcag ctaaccacca tctaagacca acagcagccg aaaaggagat
     5761 gcttgctgcc gctgtcagaa agctacgagc tagtttggag gtgacaagat gactcgagca
     5821 agtcaagaaa tgcgtcatgt ttaccgagat ttcctcattg cagccaacca agagcaccct
     5881 gaggtagtcg tcttagaggc agatttatca agctcaatgg ccaccaacca tttggatcag
     5941 gtgtttggca agcgctatat taatgtaggc attatggaag cagaaatggt cggtctggca
     6001 gcaggcctgg cgattaaagg ctataagcct tacctacaca cctttggtcc ctttgcctca
     6061 cgtcgtgtgt ttgatcagct gtttctttca ttagcctatg cccagctagg cgcaacggtt
     6121 attggctctg atgccggagt tagtgcggaa atgaatggcg gcacccatat gccctttgag
     6181 gatctgggac tgctgcgcct gattccaagg gctattgttt atgaggtcag tgatgacgtt
     6241 caatttaaag ctgttttaaa ggaaacccta tcactcgatg gcctaaaata cattcgaacc
     6301 attcgtaaaa agccagaggc tatttatcaa gggcatgagg acttttctaa tggctattgc
     6361 ctattgcgtc aaggaaaaga ccttgtgctg gcttgctcag ggatcatggt caaaaggtgc
     6421 ttagaggtag ccgataaaat ggcagagcag ggctactcta tcggtgtgat tgatgttttc
     6481 agggtaaagc cactggccga tgagctaaag ggtctactta caggcagtcc tgttctaacc
     6541 gttgaaaatc ataatcgtat cggtgggctt gggagtgcta tctgtgagct actggctcag
     6601 gaaagtaata ctccagttta ccgtatgggg gtggacgaac gtttcggtca ggtcggacag
     6661 atggattatc tattagagga ataccagctg acgccagcag ctattgagca gcaggttttg
     6721 aggattttag cggcagatta gctaaaaaag cctatcaggt gtaccacacc caaaaagctg
     6781 gaccttatag attaggattg agctttgtat gaaacagggt tcagtccttt tagttatgcg
     6841 ctttcagtcc ctttcactct gtaggcgtga aataatgatt gataactctt gatttcacct
     6901 tctaatttta atgtcataga aaaagttctt aagctttagg ttttatcttc acctttgggg
     6961 tgcaattctt ttgtcaggac tgatagggcc ttttgctatt actgctgagt ttttggcata
     7021 ttgtgagggc tgttttcatg aagctggaga agaatcgttt gatttcttag tgattgttca
     7081 gtttttatga ttaatcttac tgataaaagg accaaagcag ctaagcgttt actatctatg
     7141 ccatgcgata cgaagaatga gcttattttt gaacagaaag ttaatataaa acgagtattt
     7201 tgaacgattt tttggtaaaa tgtaagagat tacattatga ggagtaaaag ctagtcctaa
     7261 cataatggtt taatttaaaa aaggagcaat tcatgacaac atatcaagaa gatttttatc
     7321 aagccgtcaa tggtcaatgg gcagaaacag ctgttatccc agacgataag cctcgtacag
     7381 ggggcttttc agacctagca gatgagattg aggacttaat gctgaccaca acagatgctt
     7441 ggttggctgg tgagcatgtt cccaatgacg ctatattaga aaactttgtc aagtttcacc
     7501 gcttggttgc agattatgac aagcgtgatc aggtgggcgt agcgccagcc ttggacttaa
     7561 ttgaagaata caaggcctta ggatcttttg ccgagtttgc tagcaaggtg gctgattatg
     7621 agctaaatgg aaaaccaaat cagtttccat ttagtgtagc accagacttt atgaatgctc
     7681 agttaaatgt cctttgggca gaggcaccag gtcttatcct gccagatacc acttactatg
     7741 ccaaagacaa tgacaaaggc aaagagctgc ttgctatctg gcgtggcatg caagaggagc
     7801 tattgcctaa atttggcttt tcacatgaag aggttaagga cttgctggat aaggttatca
     7861 cgcttgataa acagctggca gattatgtcc tttctcgtga ggaatattca gagtatgcca
     7921 agctttacca cccttatgac tgggccgagt ttaccaagct agtgccagaa ttgcctttag
     7981 ataatatatt tactgtgatt ttaggtgaag taccagacaa ggttgttgtg ccagaggagc
     8041 ggttctggac agaatttgca gctgactatt attctgagaa gaattgggag ctgctaaaag
     8101 cctggctagt gcttacagca gcaggtgctt atcatgctta tttgactgac gagattcgtg
     8161 tgctatcagg agtttacagt cgtgccttgt caggaactcc acaggctatg gacaagaaaa
     8221 aagcagccta ttacttagca caaggaccat ttaatcaagc tcttgggctt tggtatgctg
     8281 gtgaaaaatt ttcaccagag gctaaggctg atgttgaaca caaggtagct aagatgattg
     8341 aggtttataa atctcgtctt gaaactgcgg attggcttgc accagcaaca cgtgagaaag
     8401 ccattacaaa gctaaatgtt atcaccccac acattggcta tccggaaaaa ttaccagaaa
     8461 cctatgctaa aaaggtcatc gatgataagc tatcacttgt tgaaaatgct cagaatttag
     8521 ccaaaatttc aattgctcat tcatggagca agtggaataa gcctgtggat cgtagtgaat
     8581 ggcacatgcc tgccaacatg gttaatgctt attatgaccc acagcaaaac caaattgtgt
     8641 tcccagcagc tattctgcag gcgccgtttt attcgttgag tcaaagctca tcagctaatt
     8701 atggtggtat cggtgctgtt attgctcatg aaatttcgca tgcctttgat accaacggtg
     8761 cttcctttga tgagcatggt agcctaaaga attggtggac agacgaggat tatgccgcct
     8821 tcaaggagcg taccgataaa attgtagagc aatttgatgg ccttgactcc tatggtgcta
     8881 aagtcaatgg taaattaaca gtgtctgaaa atgttgctga cctaggtggt gttgcctgtg
     8941 ccttagaggc agctcagtca gagccagatt tttctgccag agatttcttt atcaactttg
     9001 ccaccatctg gcgtatgaag gcgcgtgagg aattcatgca aatgatggca agtattgacg
     9061 tccacgcacc tggtcaatgg cgtactaatg tgaccttgac aaactttgat gaattccacc
     9121 aagaatttaa cattaaagaa ggtgatccaa tgtggcgtgc tccagaggat cgtgtgatta
     9181 tttggtaatc attgctcatt aaaaaaagac taagaggctt tgtacggccc tcctatcgtt
     9241 agaacgtata gtctagcttg tggaggaagg catgcttctc ttagtctttt tgtgttggat
     9301 aggctcgaaa agctcttttt ttaggcgtaa aaaaagattg aagatagctc ttaaaagctg
     9361 tcctcaatct tatgacttat gattagacta gttgttaagc gcagctgcca ttgtagcagc
     9421 aacctctgat tcaaagtcgt tagctttttt ctcaatacct tcaccgactt caaagcgagc
     9481 aaagctaatc gctttagcat tgactgagtc aaggtatgct tcaaccgttt tgctgtcgtc
     9541 catgatgtaa acctgagcaa gaagagtata ggcttggtca accttagtgt tatcaagcat
     9601 gaagcgatcc atcttacctg ggataatttt gtcccagatc ttttcaggct taccttcagc
     9661 agcaagctca gccttgatgt cttcttcagc ttgcgcaatc acgtcagctg ataattgagc
     9721 ctttgaacca tatttcaaga atggaagtgc tggcttgtta accattgcac gtgattcatt
     9781 gtcaagctca atagcgtggt tcaattgtgc caactcgtcc ttgataaatt gtgggtcaag
     9841 ctcagtgtat gataaaacag ttggcttcat agctgcgacg tgcattgata cttgcttggc
     9901 aagtgcttcg tctccgcctt caacaacagt gataacgcca atacggccgc cattgtgttg
     9961 gtaagcgcca aagtgttggt catcagtttt ttcaactagg gcaaagcgac ggaatgagat
    10021 tttttcaccg attgtagctg ttgcattgac ataagcatca gcaagtgttt caccagaagg
    10081 catgataaga gcaagtgctt cgtcgttatt agctggctta ccttctgcga tagcctttgc
    10141 agttgcgttt accaattcaa cgaattgagc gtttttggca acgaagtcag tttcagcatt
    10201 gacctcaaca acagcagcaa cgttaccatt aacataaaca cctgtcaagc cttcagcagc
    10261 aacgcggtca gcttttttag cggcctttgc catacccttt tcacgaagaa gctcaatagc
    10321 cttttccatg tcgccatctg tttcaacaag tgctttttta gcgtccataa cgccggcacc
    10381 agatttttca cgcaattctt ttacaagctt agctgtaatt tctgccattt ttatttcctc
    10441 caaaattaga atcggtcctc ttaaagctcg ctttagcaga gcctttgacc tgctgggttt
    10501 tcttacttaa aaaataacga gatagagcgg aatgctttgc cccgttagac catgttatga
    10561 atagcaagaa gctatcctag ttcaataagc ctgacttaag cttcgtttga accttcaaca
    10621 acctcaacga tttcttcgat tgactctgct tgagtatcag cttcaaatgc aacctctgcg
    10681 tcttcacctt gacggccttc gataacagca tcagccaatt tagcagtgat taatttgaca
    10741 gcgcggatag cgtcgtcgtt agctggaatg atcacatcaa tgtcatctgg gtcagcattt
    10801 gtatcaacca ttgccacaac tggaatacca agcttcttag cttctttaac agcgatttgt
    10861 tctttgtgtg ggtcaacaac gtacatcaca tctgggatac gaggcatatc ctcaatacca
    10921 cctaagaatt tttcaagacg tgcgcgttgc ttgttaagaa gtgcaacctc tttcttagga
    10981 agaacctcaa aggttccttc ttcttccatg cgtttgattt ctttcaaacg agcgatacgc
    11041 ttttggatag ttccccagtt tgtaagagtt ccacccaacc agcggtggtt gatgaagtat
    11101 tgacctgcac gagtagcttc gtcagcaact gcttcagcag cttgcttttt agtaccaaca
    11161 aacaagataa cagcgtcatt agctgctgca tcacgaacaa actcgtaagc ttgatcagct
    11221 aattttacag tttgttgcaa gtcgataacg tggataccgt tacgctctgt gaagatgtat
    11281 ttagccatct tagggttcca gcgacgagtt tggtgaccaa agtgaacacc agcctcaaga
    11341 agttgtttca ttgaaattac tgccatgagt agtttctcct ttatagaaat gtttttttcc
    11401 tctcttagac gtcggcttgc aactccacct gatggcaaca gaatcacaat cgatctaaga
    11461 tgagtatttg ttgtctgcac aactacaaca gtataccaaa aaaagctagt catagcaagc
    11521 ctaaatacac taaaacccac gtcgtacgca tgaggaaaat gcatgccatt attttctaac
    11581 catatgcatg ttttcaatgc atttttgata tgttgacgtt ttgacacgat ccatttttca
    11641 agcgcagctt agttttacta tcaatctttc tgaaaaagaa cacatgaatc atgaaaagat
    11701 atcagagaac ataagtttct tcaagcattt ggcgtacccc aaatgcttga tctatcagcc
    11761 ttgctgttta ttaggcctct aaaaagcaaa aaccagggta aacagttacc ttggtttttt
    11821 gctaacttac tgacgaatca ggtaatcaaa tgctccaata gcagcagtag cacctgaccc
    11881 catagaaata ataatttgtt tgtaggctga atctgtacag tcgcctgcgg caaagatacc
    11941 tggaatattg gttgaaccat atttatcaac aataatctcg ccacgatcgg ttaagctgat
    12001 accgctgtct ttgagccaag ctgtatttgg caccaagcca atctgtacaa agactccttc
    12061 aaggtcaaga tgcttttctt gattgctgtc acgctcgata tagttaagcc ctgtgacatg
    12121 atcgtcccca acaatatcct ttgtagcaac attttttaga atagtcatat tgtctgtttt
    12181 agcagcgcga tcctgtagca ccttgtcggc cttaagctca ggtaagaact caagaacata
    12241 gacatgctta gctaagccag ctaaatcaag tgcagcctca agtccagagt taccaccacc
    12301 gataacagca acgtttttat cttcaaagag aggaccgtca cagtgtgggc agtaggttac
    12361 tcctttattt ttaaactcat tttcgccagg aacattgata ctgcgccatt ttgcaccaag
    12421 cgctagaata gctgttttag ccttcaagac agcgccatta gcaagagtaa cctcaacaag
    12481 gtcttttttc tcaatcgaag tagccagctg ggctttgatg atgtcaacat cataggattt
    12541 agtatgctcc tcaacctggg ccataagctt tggtccctct gtatacaggg ttcctatcat
    12601 gttttcgata cctacagttt ccatgacttg accaccaaag gtctcagcca aaagacctgt
    12661 atttaagcct ttacgagcag catagatggc agcactattt cctgcaggtc ctccaccaat
    12721 gacaaggacg tcatagactc ctttatcagc aaaggcctcc ttagatagag gtcctgcgat
    12781 ttgctcaagc agctgctcaa tagtggcgcg accagaggtg aattcttctc cattcaaaaa
    12841 gacagttggc acagacatga tgccctttgc cttgacttcc tcttggaaca taccaccctc
    12901 aaccatagta tgtgaaatgt tcttattaag aacagccata atgttcaagg cttggaccac
    12961 atctgggcaa ttatgacacg ttaagctgac ataggtttca aagcttaaag gacggtcaat
    13021 agccctgatg cggtcaataa tatcctgctc aatctttggt gcacgtcctg aaacctgtaa
    13081 tagagcaagg ataaaggagg caaactcgtg acctagaggc agtccagcaa agatcactcc
    13141 gctgtcttga cctttttggg taatcttaaa gcttggttga cgtgttaggg tagtctcctc
    13201 aacagtgata cggtctgaca tggcagcaat ttcttcaatg aagtccttga ccttttgtga
    13261 gctatcgtca ctaccaagat aagcttgtag gactaagtca gattccaaaa gattaaggta
    13321 ttgagcaagc tgctctttaa tatcaggact taatgccata gcttttctcc tttgcctgct
    13381 taaattttgc cgacaaggtc aaggctaggt gttagtgttt cagccccttc tttccatttg
    13441 gctgggcata cttcacctgg gtgcttacga acgtactgag cagcacgaat cttatcaatc
    13501 aagctgcttg catcacgtcc gataccatca gcattgattt ccatcatttg gataacacca
    13561 tctggatcaa taatgaaagt accgcgttga gcaagtccat cctcaccaag aacatcaaag
    13621 gcttgtgaaa tagcatgtga tgggtcacca atcattgggt aagtgattgt tccgacaaca
    13681 tctgaatcat cgtgccatgc cttatgaaca aagtgtgtat cagtagatac agaataaacc
    13741 tcaacaccta aagattttag tatttcatat tgctcttgaa ggtcacctag ctctgttggg
    13801 caaacaaaag aaaagtctgc tgggtagaag caaacaactg cccatttccc tttaagatcc
    13861 tcattagtta cagtgataaa ttttccattg tgaaaagctt gggctgaaaa ttcagcaatt
    13921 tcctttccta ctaaagacat gtcatgtcct ccttttttac atttgatacc tgtattataa
    13981 gctaagaaat cttatctgtc cacttgtaaa ccctagattt atcaaggttt ttgatgttct
    14041 tttctaacaa tttcatatgt gaatttagtc acactgttta aaactattct aaataataga
    14101 aaactctgat aatatcaaag attcttgaaa ataagttttt gaaataattt taatattatt
    14161 aaaaatgatt ttctgattta aactctaaaa aataacataa accgaaaaaa ggagcagcct
    14221 gctaaaaaat agctgctatt tttatcttga cgaatgctat caactagggt aaaatagttc
    14281 ttgttatggc ggtatagcca agtggtaagg cacggctctg caaaagcttg atcgtcggtt
    14341 caaatccgtc taccgccttt tatatacaaa cgaatccttg attaacctcg taaaaacgtt
    14401 gttaaatcaa ggtttttatt ttttgtggca ggataaaaaa agagaaaaaa agaaataaag
    14461 tcggtcaaaa gtcggtcaaa tttccaaaaa tatcttttat ggcctgattg ttcttttctt
    14521 ttagcttatc tagctgatgg gcatatacct taagcgtaat gttcaaattc tcatgcccaa
    14581 gcaactgaga tatggatatt aggtcaacac cctttaagat taaaaaagat gcgtaagtat
    14641 gacgtagaga gtgattgcgt acaggacgac caacaatttt tttaaccaat ctattgcaga
    14701 gtgaattaga agctccgtag agcaccctat ttagcttatt ttcattataa taattttctt
    14761 taaatgctct aagcaatttt atagtttgct gatcaatggg aatttgtctt tttgattgct
    14821 cgttttttgt ttccttaaat tcttgagttt ttgagtaatc aaacgattta ttaatatcta
    14881 taaatccctt ctcaaagtct atatcgctcc aagttatccc ggtcgcttcg gcgaatcgta
    14941 gtccagtcac tgctatgatg tataaagtaa aataggaaac atactggtat ttctcactcg
    15001 ttactttgat tagatttaga tattcatctt cttcaaggaa atcaaattct tttgctctag
    15061 cttctttttg agattttaca atcgcacctt cggcaaaatt tgttttgata agcccatctc
    15121 taactgctac attaacagct ccttttattt gatagtggag tttttcgagt gtttcttggg
    15181 catatttttt ggcaaattcg ttgattgttt tttggtaaaa ggtatgcgtt acattattaa
    15241 gcttaatatc accaaaatat tttttgatgt gcttaagatt tttagtgtaa gtttcccaag
    15301 ttttatcgac aacatgcgga cgtttgtaga ttttagccca ttccttgcaa aaatcataaa
    15361 gtgatatatc atcaatatct ttatttagct cagcctcgac tttaatcgca gctgcagaag
    15421 ccaatgcttt tgtcttaaaa ccacctttgg atttttccct tttgttcccc tgactatctg
    15481 tgtagtaaat acgataagac cacttgtcgc cgcgttttct aaattttgcc attgttaatt
    15541 acctcatttt tatgttaaaa tgggtacagt aaagagacct actgcgaagc aggtttttta
    15601 ctatacagga tttgcctcac gctcagactc gccaaagttt gagagcgtgg ggcttttttt
    15661 aacgtttgat tttatagact gagcttcgat gctctatttt aaaaacttcg atgacaactt
    15721 cgtcatcaat aatctcagct aaaatacgat agtttcctaa acgataacgc cactctcctg
    15781 tacgattagc ttgtaaagct tttccgtatc tccttgggtt atctgtgcca tcaaggttag
    15841 tcattatcca ctgatagagt tgtttagcag tagatctatc taattttttg agttgttttt
    15901 tggctttttt agtaaacaat actttataac gcaaaaccta gctccttcgc tacatcttcc
    15961 atgctaaatc gtgtcccatc gtcctcagcc ttagcttttc tcaattcgta caaatcttta
    16021 gcatcttcaa tgatttccaa aaactggtca actgttagat tggaggtgtc aatgttattt
    16081 tctttgatgt aatctgcgat ataagcatcg tctttttcaa ggtttaatgt cattgcaatc
    16141 atagtatttt tctccttcta tatttctact ggtgtaaagc tgccgacgac atcatagatt
    16201 ttgatgtaag tatcttctgc tggcgggtag tcgataaaga tatcattgta ttttttattg
    16261 agagatacta atctaagccc gtcttcctct gtgtatactt ttttaaaata ggtctgtccg
    16321 ttatgcacaa ctatacatag ctgaccggca tatgctgaca tgccccgatc tacaatatag
    16381 agcatatctc cttgctcgta ctttggtagc atactatcgc cccgcactcc aattgcatag
    16441 tcgtagtgag gtggttcttc gtcagtgtag acagtatatg tgtcatattc atctgcttca
    16501 aatccacgac caaagccact tgcggctgcc gcgtaagtta cgccttgaac cgaaaataat
    16561 tcttcatgcg tagaaacaac tttattttgt tcttccaatt gctccttggc aaagtcaagg
    16621 actttttctt gtctaggttg ttctagttgg ttgtagatgg acactatttc agatgtattt
    16681 tttggggcat ctagcagaga cgaaaacacc tcgggtctga tacctaaagc tgagcaaatt
    16741 tttatggcat tctcgacgtt agcattcatt attcctcgct ctaatatcga gcgaaccgtt
    16801 gagtaaggca tgttgttttc ttctgcaaaa gattttacag agctataacg agaaagtata
    16861 agatgtttta gattttcttc attcatggct gcctctcttt ctgatttcat tataacacac
    16921 gatttttcgt ttgtctaaca aaaaaacact aagaaatacg aattttagta ttgacaaaca
    16981 cgaaaaaaag tattaaactt gtatcaagct cagatgagct taactttaaa accaaaaaca
    17041 cgaaaaatcg tgttagaaag gagttatatg ttaaatattg ataaagtgcg aaaagaaaaa
    17101 ggcgtagcaa tagtagacat ggctgatttt cttggcgtaa gagctcaaac agtaagcgat
    17161 aaattgcgcg ggacttacga ttttaaattt actgaggctt tggcgttgca acaaaaattt
    17221 ttcccggagt acgatttaga atatcttttt aacaaagcag tagacactgc ttaactttaa
    17281 aaccaaaaac acgaaaaatc gtgtt
//
LOCUS       DARYNN010000043        17118 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.043, whole genome shotgun sequence.
ACCESSION   DARYNN010000043 DARYNN010000000
VERSION     DARYNN010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17118)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17118)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17118
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.043"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(329..883)
                     /locus_tag="TVB59_001513"
     CDS             complement(329..883)
                     /locus_tag="TVB59_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010392.1"
                     /translation="MRLKKLIYSSIAALAILTYGTISANADASIPEIDQTEVITILKS
                     DGYLNIDEGTQEVTITEKYKQAVLSSIDLDRQEAIFTENSVTIRDIFSPRSFTGVNKI
                     VFTWKGYDLYLDSTNANRLSALGWGSTALSGLIPDPIVSKVLAAALGVVSASISYANA
                     AGRGVIVAFVGTFPRGVIHWVASQ"
     gene            1152..1362
                     /locus_tag="TVB59_001514"
                     /pseudo
     CDS             1152..1362
                     /locus_tag="TVB59_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679490.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1454..5089)
                     /gene="rpoC"
                     /locus_tag="TVB59_001515"
     CDS             complement(1454..5089)
                     /gene="rpoC"
                     /locus_tag="TVB59_001515"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEL1010393.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRAKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEPKSLLTEREYREKIQ
                     EYGHGSFIAKMGAEAIQDLLKRVDLVTEIAELKEELKTATGQKRIKAVRRLDVLDAFH
                     KSGNKPEWMILNILPVIPPDLRPMVQLDGGRFAASDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVIREIVAREFAGNVKAAKRMVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARLLMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEDA
                     GREGEGMVFKDKDEAVMAYRNGYVHLHSRVGIAVDSMPSKLWKDSQRHKIMVTTVGKI
                     LFNDIMPEDLPYLQEPNNANLTEGTPDKYFLKPGQNIQEVIDSLPINVPFKKKNLGNI
                     IAETFKRFRTTETSAFLDRLKDLGYYHSTLAGLTVGIADIPVIDNKAEIIEAAHHRVE
                     EINKAFRRGLMTDDDRYVAVTTTWREAKEALEKRLIETQDPKNPIVMMMDSGARGNIS
                     NFSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADS
                     GYLTRRLVDVAQDVIIREDDCGTDRGLLIRAITDGKEVTETLEERLQGRYTRKSVKHP
                     ETGEVLIGADQLITEDMARKIVDAGVEEVTIRSVFTCATRHGVCRHCYGINLATGDAV
                     EVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRIQEIFEARNPKGEAV
                     ITEVKGTVIEIEEDASTRTKKVYVQGKTGMGEYVVPFTARMKVEVGDEVNRGAALTEG
                     SIQPKHLLEVRDTLSVETYLLAEVQKVYRSQGVEIGDKHVEVMVRQMLRKVRVMDPGD
                     TDLLPGTLMDIADFTDANKEIVISGGIPATSRPVLMGITKASLETNSFLSAASFQETT
                     RVLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMVRYRNIEPQAINEVEVIEEAEATE
                     EPAIIKE"
     gene            complement(5180..8746)
                     /gene="rpoB"
                     /locus_tag="TVB59_001516"
     CDS             complement(5180..8746)
                     /gene="rpoB"
                     /locus_tag="TVB59_001516"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEL1010394.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFQDFLDSG
                     LKEVFEDVLPISNFTDTMELEFVGYEFKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELETDSKDIAYTRIDRTRKIPFTTLVRALGFSGDDEIIDIFGDSELVR
                     NTIEKDIHKNQSDSRTDEALKEIYERLRPGEPKTADSSRSLLTARFFDARRYDLAAVG
                     RYKINKKLNIKTRLLNQIIAENLIDSETGEILVEAGTEMTRSVIESIEEQLDGDLNKF
                     VYTPNDYAVVTEPVILQKFKVVSPVDPDRVVTIVGNANPDDKVRALTPADILAEMSYF
                     LNLAEGLGKVDDIDHLGNRRIRAVGELLANQFRIGLARMERNVRERMSVQDNDVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSFGHLNKYGFIQTPYRKVDRVIGRVTNEIV
                     WLTADEEDEFTVAQANSKLNPDGTFAEEIVMGRHQGNNQEFPASQVDFVDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLIDPKAPYVGTGMEYQAAHDSGAAVIAQH
                     NGKVVFSDAERVEVRREDGSLDVYHITKFRRSNSGTAYNQRTLVKIGDIVEKGDFIAD
                     GPSMEKGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKEDVYTSVHLEEFESETRDT
                     KLGPEEITREVPNVGEEALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGGDGIVRDVKIFTRANGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARNLGIHIATPVFDGATSEDLWETVREAGMDSDAKTVLYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDVNGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDN
                     EVELRDLDEGEDDDVMHVDDLEKAREKQAQETQDIAESTEDN"
     gene            complement(9008..11308)
                     /locus_tag="TVB59_001517"
     CDS             complement(9008..11308)
                     /locus_tag="TVB59_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014611927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEL1010395.1"
                     /translation="MVKWKKNQTSKNHQRLELVDFGTVFLRTLKFMSSFFYVAVFLFG
                     MLGAGMAFGYLASQIDSVKIPSKESLVKQVESLTMMSQITYSDNSLISGIDTDLLRTP
                     VANDAISDNIKKAIVSTEDDNFQRHNGIVPKAIFRATLASVLGFGESSGGSTLTQQLI
                     KQQVLGDDPTFRRKSKEIIYALALERYMSKDDILSHYLNVSPFGRNNKGQNIAGVEEA
                     ARGIFGVSAKDLTVPQAAFLAGLPQSPIVYSPYLPTGQLKSADDMAYGIKRQQNVLYN
                     MYRTGVLTEKEYRDYKAYPISNDFIKPETVTANTHDYLYYSVLAEAQKAMYSYLIKRD
                     KVPAKDLKNDETKAAYEERALTELQHGGYTVKTTINKPIHQVMQKAAAQFGGLLDDGT
                     GTVQMGNVLTDNATGAVLGFIGGRDYAQNQNNHAFNTVRSPGSSIKPIIAYGPAIDQG
                     LMGSASVLSNYPTTYSSGQKIMHVDSEGTAMMPLQEALNTSWNIPAFWTQKLLRDKGV
                     DVENYMSKMGYRIADYSIESLPLGGGIETSVAQQTNAYQMIANNGLYQKQYMVASITA
                     SDGSVVYQHEAKPVRIFSAPTATILQELLRGPISSGATTTFKSRLAGINPSLAGADWI
                     GKTGTTENYTDVWLVLATPRVTLGGWAGHDDNTSLAPLTGYNNNSNYMAYLVNAISQA
                     DPNLFGLGQRFSLDPGVIKASVLKATGLKPGTVTINGQTISIGGELTTSLWAQKGPGA
                     TTYRFAIGGTDADYQKAWGGFSGRRN"
     gene            11413..12669
                     /locus_tag="TVB59_001518"
     CDS             11413..12669
                     /locus_tag="TVB59_001518"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEL1010396.1"
                     /translation="MNIFEELKARGLVFQTTDEEALVKALTEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERILQTKETVLDWSQKIK
                     EQLSCFLDFDNGENKAELVNNYDWFSQISFIDFLRDVGKHFTINYMMSKDSVKKRIET
                     GISYTEFAYQVMQGYDFYELNAKHNVTLQIGGSDQWGNMTAGTELLRKKADKTGHVMT
                     VPLITDATGKKFGKSEGNAIWLDAKKTSPYEMYQFWLNVMDDDAVRFLKIFTFLSLDE
                     IAAIEEQFNAARHERLAQKTLAREVVTLVHGEAAYQQALNITEQLFAGAIKNLSAAEL
                     KQGLSNVPNYQVQAEDSLNIVDMLVTAGISPSKRQAHEDLQNGAIYLNGERLQDLDYS
                     LSTADRIDNQLTVIRRGKKKYAVLTY"
     gene            complement(12704..13513)
                     /locus_tag="TVB59_001519"
     CDS             complement(12704..13513)
                     /locus_tag="TVB59_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEL1010397.1"
                     /translation="MLEILSYDFMQRAVMAVVAISIFAPILGIFLILRRQSLLSDTLS
                     HVSLAGVAFGVVLGVSPTFTTIIVVVLAAILLEYLRVVYKHYMEISTAILMSLGLAIS
                     LIIMSKSTSSSSMSLEQYLFGSIITISTEQVAALFVIALIILALTILFIRPMYILTFD
                     EDTAYVDGLPVRVMSVLFNIVTGVAIALTIPAAGALLVSTIMVLPASIAMRLGKNFKS
                     VIFLGIMIGFTGMLSGIFLSYFWETPASATITMIFIAIFLVVNLLSFIRQK"
     gene            complement(13506..14225)
                     /locus_tag="TVB59_001520"
     CDS             complement(13506..14225)
                     /locus_tag="TVB59_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEL1010398.1"
                     /translation="MRYISVENLSFQYDSEPVLEGISYHLDSGEFVTLTGENGAAKST
                     LIKATLGILKPRAGQVTIAKQNIHGKKLRIAYLPQQVASFNAGFPSTVYEFVKSGRYP
                     RSGWFTRLSKHDEEHVRTSLESVGMWDSRHKRIGSLSGGQKQRVVIARMFASDPDIFV
                     LDEPTTGMDSGTTDTFYELMHHSAHRHGKAVLMITHDPEEVKAYADRNIHLIRNQRLP
                     WRCFNIHDAEADESKGGSFHA"
     gene            complement(14228..14671)
                     /locus_tag="TVB59_001521"
     CDS             complement(14228..14671)
                     /locus_tag="TVB59_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent MarR family transcriptional
                     regulator"
                     /protein_id="HEL1010399.1"
                     /translation="MTILEKKLDNLVNRILLKAENQHELLFGACQSDVKLTNTQEHIL
                     MLLSQEKLTNTDLAKRLNISQAAVTKAIKGLIKQEMLAGTKDTVDARVTYFELTDLAR
                     PIAKEHTHHHDKTLAVYHRLLAHFSAEEQVIVEKFITAFAEELEG"
     gene            complement(14741..15592)
                     /locus_tag="TVB59_001522"
     CDS             complement(14741..15592)
                     /locus_tag="TVB59_001522"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HEL1010400.1"
                     /translation="MTAIIERAPAKINLGLDIQGKRPDGYHDLSMVLVSVDLCDYITV
                     DHLEEDRILLTSNCPRLPINEHNDVYKAAYLLKERFQISTGVSIFLDKRVPVCAGMGG
                     GSSDAAAAIRALNQLWQLKLSPRQMIDIGMQIGSDVPYCLFAGCAQVTGKGEVVKPIN
                     GRLSSWVVLVKPEFGISTRTIFWDIDCETISRVPIEDLVSAIEAGDYQRLLATMGNSL
                     EDISIAKRPFIQKVKDKMLQSGADIALMTGSGPTVFALCQTEKQANRVVNSLKGFCKE
                     VYKVRTL"
     gene            complement(15807..16331)
                     /locus_tag="TVB59_001523"
     CDS             complement(15807..16331)
                     /locus_tag="TVB59_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HEL1010401.1"
                     /translation="MVEYWDIYTMNRLKTGRLMERGAAFVEGAYHLVVHACVFNDKGE
                     MLIQQRQKDKEGWPSYWDITVGGSALAGETSQEAVMRELKEELGLTLDLAGVRPHFSI
                     TFDNGFDDTFLILQAVDVRKLVLQTEEVQAVRWASRDEILAMIDAGIFIPYFKSKIDM
                     CFELVGQYGAIKWS"
     gene            complement(16825..16926)
                     /locus_tag="TVB59_001524"
                     /pseudo
     CDS             complement(16825..16926)
                     /locus_tag="TVB59_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407887.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
BASE COUNT         5084 a         4136 c         3224 g         4674 t
ORIGIN      
        1 ccataaaacg aaggaattaa ctccttcgtt ttctttcaat ttttcttgga atatttttat
       61 agacttttct tacggatata gtaagaataa ctaccagcaa taatgacata attcaataaa
      121 agacataatt aatcacaact tgattgtctt tctaacaaat ccattccctg cctggatcat
      181 tagtatacga aaaaaatgat aggtaaaact atacccaata ggcagaaaaa aactttccaa
      241 aaaatagtat tatttttaaa taatttatca acaaacacca ataatatcaa attaattgct
      301 aaacacagta tttttaaata taatgctatc attgtgaagc cacccaatgt atcacacctc
      361 ttggaaaagt tcctacaaag gcaacaatta ctcctcttcc tgcagcatta gcataagata
      421 ttgatgcaga cacaactcct aaagcggctg caagtacctt agatactata gggtctggaa
      481 taagacctga caaagcagtt gatccccagc ctagtgcaga taatctattc gcattggtac
      541 tatctaaata aagatcatag cctttccaag taaaaacaat tttatttacc ccagtaaatg
      601 atctaggact aaatatatct cttatagtaa cagaattttc agtaaaaatt gcttcttgtc
      661 tatctaaatc aatagaagat aaaactgctt gtttatattt ttctgttata gtaacttctt
      721 gagtaccttc atcaatattt aaatacccat cagattttaa aatagttatt acttcagttt
      781 gatcaatttc tggaatagag gcatcagcat tagccgaaat agtaccgtaa gttaaaattg
      841 caagcgcagc gatactagaa taaataagtt tttttagtct cataatctac tcctttttaa
      901 tctctaaaat taaaacaaac aatctttacc ggtaatagtt aattttacta ctaaaaataa
      961 actcctttct ggtaaaatga accacctaag aaacctacat gtacagaata acatatattt
     1021 tccttaaaaa taagactata ttttaaaaaa acaaatgata aaattaaatt ttggaagctt
     1081 tttttataat aaaataattt atcgattttt ccactattaa gttatttttg attaacattt
     1141 ttaaaatagt tttgtctatc tacatacaat ataaagacta tatcactaat gccattgaac
     1201 taccttattc taacgccaag tttgaagcga ctagcaaact gatcaaagac atcaagcgca
     1261 atgcatttgg attcagaaac gttgacaatt tcaagaaact tatctatgct tgctttgaac
     1321 atgacaaaag agaagacgac cttcgtctcc tctcgtgctt agttatcagt cacctactat
     1381 agttgacatg gagcccaatt aatctaatga ttttagcatg ataaaaggag ctaaggctag
     1441 ctccttttat ttcttattcc ttaataattg ctggctcttc tgtagcttca gcttcttcga
     1501 taacctcaac ctcattgata gcttgcggtt caatgttacg gtaacgaacc ataccagtac
     1561 ctgctggaat gatcttacca atgataacat tttccttaag ccccaataga tggtcttttt
     1621 tgcctcggat agcagcgtct gtcagcacgc gagtggtttc ctggaaggaa gctgctgata
     1681 ggaatgagtt agtctcaagt gaggcttttg tgattcccat aagcactgga cgagaggtcg
     1741 caggaatacc tccagagata acaatctcct tattggcatc tgtaaagtct gcaatatcca
     1801 ttaaggttcc tggcagaaga tctgtatcac ctggatccat gacacgtacc ttgcgaagca
     1861 tttgacgaac cataacctca acgtgcttgt ctccgatttc taccccttgg ctgcggtaaa
     1921 ccttttgaac ctcagcaagc aagtaggtct caactgacaa ggtatcacga acctcaagga
     1981 ggtgcttagg ctggattgac ccttctgtaa gggcagctcc acgattgacc tcatcaccaa
     2041 cctcaacctt catacgcgct gtaaatggca caacatattc acccatgcct gttttacctt
     2101 gaacgtagac cttcttagta cgagttgatg cgtcctcttc aatctcaata acagtcccct
     2161 taacctctgt gataactgct tcccctttag ggttgcgcgc ttcaaagatt tcttggatac
     2221 gaggaagacc ctgtgtgata tcggtattag aggcaacccc tcctgtgtgg aaggtacgca
     2281 tggtcagctg agtaccaggc tcaccaatag attgggcagc gatagtacca acagcctcac
     2341 caacctcaac cgcatcacct gtcgctaggt tgataccgta acagtgacga cacactccat
     2401 gacgagtagc acaggtaaat actgagcgaa tggtaacctc ttcaacacca gcatcaacaa
     2461 tcttgcgagc catgtcctca gtgattaatt ggtcagcacc aatcaatacc tcaccagttt
     2521 cagggtgctt gactgattta cgagtgtatc gaccctgcaa gcgctcctca agtgtttcag
     2581 tgacttcctt gccatctgtg atagctcgaa taagaaggcc tcggtctgta ccacaatcgt
     2641 cctcacgaat gatgacatct tgcgcaacat caactaaacg acgtgtcaga tagcctgagt
     2701 cagctgtctt aagagccgta tcagtcatac ccttacgagc accatgagtt gagaagaaca
     2761 tttccaaaac agacaagcct tcgcggaagt tagacaggat aggaagctcc ataatacggc
     2821 cattaggagc agccatcaag ccacgcatac cggcaagctg cgagaagtta gagatgttac
     2881 cacgcgctcc tgagtccatc atcataacga ttgggttctt aggatcctgt gtttcaatca
     2941 gacgcttctc aagggcttct tttgcctcgc gccatgttgt tgtgactgca acatagcgat
     3001 catcatcagt catcaagcct cgacggaagg ccttattaat ttcctcaaca cgatggtgag
     3061 cagcctcgat gatctcagcc ttgttgtcaa taaccggaat atcagcgatc ccaaccgtca
     3121 agcccgcaag ggttgaatga tagtagccaa ggtccttcaa gcggtcaaga aaggccgatg
     3181 tttctgttgt acggaaacgc ttgaaggttt ccgcaatgat gttaccaaga tttttcttct
     3241 tgaagggcac attgatcggt aagctatcaa taacctcctg aatattctga cctggcttca
     3301 agaaatattt atctggagtg ccctctgtca agttagcatt atttggctct tggaggtaag
     3361 gaaggtcctc tggcatgatg tcattaaaca agatcttacc gaccgttgtc accatgattt
     3421 tgtgtctttg actatccttc caaagcttgc ttggcatact gtcaacagca ataccaacac
     3481 gactatgaag gtgaacatag ccattacggt aagccattac cgcttcgtcc ttgtccttaa
     3541 agaccatacc ttcgccttca cgaccagcat cttccattgt taggtagtag tttcctagca
     3601 ccatatcctg agaaggtgtt acaactggct taccgtcctt agggttaaga atatgctcag
     3661 cagcaagcat caacaaacga gcctctgcct gtgcttcctc tgaaagcggc acgtgaatag
     3721 ccatttggtc tccgtcaaag tcggcattgt aggcctcaca cacaagcggg tgaagacgaa
     3781 gagccttacc atcaataagc accggctcaa aggcctgaat ccctaatctg tgaagggtag
     3841 gtgcgcggtt aagcaggact ggatgctcct tgataacctc ttctagaata tcccagatac
     3901 gctcatcgcc acgctcaacc atacgcttag ctgctttgac gttgccggca aattcgcggg
     3961 caacaatctc acgtatcaca aatggcttga aaagctcaat agccatctca cgtggtacac
     4021 cacattggta catttttagc gttggaccca cagcaataac tgaacgacct gagaagtcaa
     4081 cacgcttccc aagcaggttt tgacgaaaac gcccttgttt tcctttaagc atgtggctca
     4141 aggatttaag cggacgacta ccaggtcctg taataggacg accacgacga ccattatcaa
     4201 tcaaagcatc aaccgcctct tgcagcatac gcttttcatt ttgcacaatg ataccaggcg
     4261 cattaagctc caacaaacgt gctaaacgat tattacggtt aatgacacga cggtaaaggt
     4321 cattcaagtc tgaggctgca aagcggccac cgtccaattg caccatagga cgaagatctg
     4381 gtggaatgac cggcaagatg ttcaggatca tccattctgg cttattgcct gatttatgaa
     4441 aggcatcaag cacatctaac cgacgaacag ccttgatacg cttttggcct gttgctgttt
     4501 ttaattcttc ctttagctca gcaatttctg tgaccaaatc aacacgcttt aggaggtctt
     4561 gaatagcctc tgcccccatt ttagcaatga atgagccatg tccatattct tggatttttt
     4621 cacgatattc acgctctgtc aatagtgatt ttggctcaag cggtgtgtcc tttggatcaa
     4681 taaccacata agccgcaaaa tagattacct cctcaagagc acgaggactc atatcaagag
     4741 tcaagcccat acgagatggg attcccttaa aataccagat atgtgagaca ggtgccttca
     4801 gctcaatgtg tcccatgcgt tcacgacgaa cctttgcacg cgttacctcg accccacaac
     4861 ggtcacagac aatgccctta tagcgaatac gtttatattt gccacacgca cactcccaat
     4921 ccttggttgg tccaaaaatg acttcgtcaa aaagaccctc acgttctggt tttaatgtac
     4981 ggtagttgat tgtttcaggt tttttaactt caccatagga ccatgaacgg accttacttg
     5041 gtgaagctaa tgtgatttgc atacttttaa aacgatttac gtcaaccact agttttacct
     5101 ttctgccttt gatgacttac tagcagctag ggcaaatagc cctagtctag tcattatttc
     5161 tgttacaaat gtttatgatt tagttgtctt cagttgattc agcaatatct tgagtttcct
     5221 gagcctgctt ttcacgcgct ttttcaagat cgtcaacgtg catcacgtca tcgtcttcgc
     5281 cttcatcaag atcacgaagc tcaacttcat tatcgtcttc atcaaggaca cgcatatcaa
     5341 gaccaagtga ttgcaattct ttcacaagaa cgcggaaaga ttctggtaca ccaggctttg
     5401 gaattggctt acctttggta atcgcctcat aagctttcaa gcgaccattc acatcgtctg
     5461 acttataggt caagatttcc tgaagaacgt ttgaagcacc ataagcctca agagcccata
     5521 cctccatctc accaaaacgt tggccaccaa actgagcttt acctccaagc ggctgttggg
     5581 taaccagtga gtatggtcct acagaacgcg cgtgaagctt atcatcaacc atgtggtgaa
     5641 gcttaatcat atacatgaca ccaactgaca cacgattatc aaacggctca ccagtacggc
     5701 catcataaag aacagtctta gcatcgctat ccatacctgc ttcacgaaca gtttcccaaa
     5761 ggtcctcaga cgtagctccg tcaaagaccg gtgttgcgat atggataccc aaattacgag
     5821 cagccatacc taggtgaagc tccataacct gtccaatgtt catacgagac ggcaccccaa
     5881 gagggttcag catgatgtca acaggggttc cgtctggcag atatggcata tcctcaaccg
     5941 gtacaatacg tgagacgaca cccttgttac catgacgccc ggccatttta tctccgacct
     6001 tgattttacg cttttgagca atgtaaacac gcaccagcat attaacacct gattgaagct
     6061 catcaccatt tgcgcgtgta aagatcttca catcacgtac aatcccgtca ccaccatgag
     6121 gaacacgtaa cgaggtatca cgaacctcac gtgatttatc accaaagata gcatgcagga
     6181 gacgttcttc agcagaaagg tctttttcac ccttaggagt taccttacca acaagaatat
     6241 cgccttcctt gacctctgca ccgatacgga taatacccat ttcatcaagg tccttgaggg
     6301 cttcttcacc aacgtttggc acttcacgtg tgatttcctc aggtccaagc tttgtgtcgc
     6361 gtgtttctga ttcaaactcc tccaagtgaa cagaggtata aacgtcctcc ttcacaagac
     6421 gctcactcat gataaccgcg tcctcaaagt tgtacccttc ccaggtcatg taagcaacga
     6481 ttggattttg accaagagcc atctcacctt tttccataga agggccatca gcgataaagt
     6541 cacccttttc aacaatatca cctattttaa caagggttcg ttggttgtag gcagtaccag
     6601 agtttgaacg gcggaatttt gtgatgtggt aaacatcaag tgaaccgtcc tcacgacgca
     6661 cctctactct ttcagcatct gaaaagacaa ccttaccatt atgctgggca attaccgcag
     6721 cacctgaatc atgagctgct tgatattcca tacccgtacc aacataagga gcctttggat
     6781 caatcaatgg cacagcctga cgctgcatgt tagctcccat tagggcgcgg ttggagtcat
     6841 cgttttcaag gaaaggaata catgctgtcg caacagcgac tacctgctta ggagacacgt
     6901 caacaaagtc aacctgacta gcaggaaact cttggttatt accttggtga cgtcccatga
     6961 caatctcttc agcaaaggta ccgtctggat tgagcttaga attagcctga gccactgtaa
     7021 actcatcctc ttcatcagca gttagccaaa caatctcatt agtcactcgg ccaatcacac
     7081 gatcaacctt acggtaaggg gtttgaataa agccgtattt gttcagatgt ccaaatgaag
     7141 acaggttatt aatcaaaccg atatttggcc cttcaggtgt ttcaatcgga cacatacgac
     7201 catagtgagt gtagtgcacg tcacgcacct catagccagc acgatcacgt gtcaaaccac
     7261 caggtcctaa ggcagacaaa cgacgtttgt gcgacaactc agacaatggg ttgtgctgat
     7321 ccatgaactg tgatagctgt gaagaaccaa agaattcttt gacagccgcc gttacaggac
     7381 gaatgttaat aatctgttgt ggagtcaaca catcgttatc ctgtacagac atacgctcgc
     7441 ggacattgcg ctccatacga gcaagaccaa tacggaattg gttagcaagc aattcaccaa
     7501 ctgcacggat acgacgatta cctaagtggt caatgtcatc gacctttcca agaccttcag
     7561 caaggttaag gaaataagac atctcagcca aaatatcagc cggagtaagg gcacgaacct
     7621 tatcatctgg gttagcatta ccaacgatcg tcaccacacg atcaggatca actggtgaaa
     7681 ccaccttgaa tttttgtagg atcacaggct ctgtcaccac cgcataatcg tttggtgtgt
     7741 agacaaactt gttcaaatcc ccatcaagct gctcttcgat tgactcaatc acactacgag
     7801 tcatctctgt tccagcctca accagaatct ctccagtctc actatctatt agattttcag
     7861 caataatttg attcaaaaga cgtgtcttga tgttcagctt tttattaatc ttataacggc
     7921 caactgctgc caagtcataa cggcgagcat caaagaaacg agctgtcaaa aggctgcgtg
     7981 agctatcagc tgtctttggc tcacctggtc ttaagcgttc ataaatttcc ttaagagcct
     8041 catctgtacg tgaatcgctt tggtttttat gaatatcctt ttcaatggta ttgcgaacaa
     8101 gctcactatc accaaaaata tcaataattt cgtcatcacc agaaaaacca agtgcacgca
     8161 ctagcgttgt aaatgggatt ttacgcgtac ggtcaatacg agtataagca atatcctttg
     8221 agtcagtttc tagctctagc caagcaccac gattagggat aactgttgag ccataaccaa
     8281 ccttaccatt tttatcaacc ttgtcattga aataaacacc aggagaccga accagctgag
     8341 aaacaataat acgctctcca ccgttgatga taaaggttcc catttcagtc ataatcggaa
     8401 aatcaccaaa aaagacctct tgtgttttga tttcgccagt ttccttatta atcaggcgga
     8461 aggtcacaaa gattggtgca gaatagcttg catcatggat acgagcctct tcaagggtat
     8521 atttaggctc cttaaattcg taaccaacaa actcaagctc catcgtgtct gtaaagtttg
     8581 agattggaag cacatcttca aatacttcct tcaagcctga atctaagaaa tcttggaatg
     8641 aatcagtttg aatttcaatc aaatttggta aatcaagaac ctctttgatt cttgaaaaac
     8701 tacgacgggt acgatgtttc ccgtattgaa cgtcatgtcc tgccaagttt ttagctcctt
     8761 tttcttttta agctttgcta tcaagcaaac aattgcaaca tcaatatttg tcttaagtgg
     8821 tatttttaga atctttaaat ttttgttaca aaattgattt ttatctaaaa ataggcacaa
     8881 aaagagcagc taaatcggac cttatcagtg tgatttaact gctgttcttt ctagctggac
     8941 aatatttcag ctagattaga cgacaaatag ttatagatat tatacactat ttgtctggaa
     9001 aatacaacta atttcttcta ccactaaaac ctccccaggc tttttgatag tctgcgtctg
     9061 ttccaccaat ggcaaaccta taggtagttg ctccgggtcc cttttgagcc caaaggctgg
     9121 ttgttagctc tccaccgatg gagatggttt ggccattgat cgtcactgta cccggcttta
     9181 gaccagtggc cttcaagaca gaagccttga taacaccagg atccagtgaa aaccgctgac
     9241 caaggccaaa aagattggga tcagcctgac tgatggcatt aaccaaataa gccatataat
     9301 ttgaattatt attgtatccc gtcagtggtg caagcgaggt attgtcatca tggcctgccc
     9361 aaccacccaa agtaaccctt ggagtagcta agaccagcca gacatcggta taattttcgg
     9421 ttgttcctgt tttacctatc cagtcagcac ctgcaaggct tgggttgatc cctgctaatc
     9481 ggcttttaaa agtggttgtt gccccagatg aaatcggccc tctcaagagc tcctgtaaaa
     9541 tcgttgctgt cggagctgag aaaatacgaa ccggcttggc ctcatgctga taaacaacgg
     9601 atccatcact agctgtgata ctagccacca tatattgctt ttgataaaga ccattattag
     9661 caatcatctg ataagcattg gtctgctggg ctaccgaggt ctcaatccca ccaccaagtg
     9721 gcagactttc aatggaataa tcagcaatcc gatatcccat tttactcata tagttttcaa
     9781 catcaacgcc cttatcacgc agcagctttt gagtccaaaa ggctggaata ttccatgagg
     9841 tattaagcgc ctcctgcagg ggcatcattg ctgttccttc actatcgacg tgcatgattt
     9901 tttgaccgct ggaataggtc gtcggatagt tggataggac actagcactt cccattaatc
     9961 cctgatcaat ggcaggtcca taagcaataa tcggcttaat gctagagcct ggagagcgaa
    10021 cagtattaaa ggcatgattg ttttgatttt gagcatagtc tctcccacca ataaagccca
    10081 aaacagcacc tgtagcattg tccgttagga cattgcccat ctgcactgtc ccagtgccat
    10141 catctaacaa gccaccaaac tgagctgccg ctttttgcat cacctgatgg attggcttat
    10201 tgattgttgt tttgacagtg tagccgccat gctgcagctc agttaaggct cgctcctcat
    10261 aggcagcctt agtctcatca ttttttaaat ctttagcagg caccttatct cgcttaatca
    10321 gatagctata catggccttt tgtgcctctg ccaagacaga atagtagagg taatcatgag
    10381 tattggcagt gactgtttca ggtttgataa aatcattgct aataggatat gccttataat
    10441 cacgatattc tttttctgtc agcacacctg ttcgatacat attgtagagg acattttgct
    10501 ggcgcttaat cccataggcc atatcatcgg ctgattttaa ctgccctgtc ggcaaatacg
    10561 gcgaataaac aatcgggctt tgcggaagcc ctgccaaaaa ggccgcctgc ggaaccgtca
    10621 aatccttggc agagactcca aaaatgccac gcgcagcctc ctccacacct gcaatgtttt
    10681 gtcccttatt attacgacca aaaggcgaca cgtttaaata atgtgataaa atatcgtcct
    10741 ttgacatgta acgctctaag gccagtgcat agataatttc ctttgatttt cgcctaaagg
    10801 tcggatcatc gcccaagact tgctgcttaa tcaactgctg tgtcagcgta gagccaccac
    10861 ttgactcccc aaagcccaaa acagaggcca gagtcgcacg aaaaatcgcc tttggcacaa
    10921 tgccattatg gcgctgaaag ttgtcgtcct cagttgagac aatagccttt ttgatattgt
    10981 ctgaaatcgc atcattagca accggtgtcc taagcagatc cgtatcaatg cctgaaatca
    11041 agctattatc tgaataggta atctgtgaca tcatggtcaa tgattcaacc tgcttgacaa
    11101 gactttcctt acttggaatt tttaccgagt caatttgact ggctaaatag ccaaaggcca
    11161 taccagcacc cagcatgcca aataaaaaga cagctacata aaaaaagctc gacatgaatt
    11221 ttaatgtgcg caaaaagacc gttccaaaat caactaattc taatcgctga tgatttttgc
    11281 ttgtttgatt ctttttccat ttcaccataa cgtacctcaa tcttcattat accaaacttt
    11341 gattaagctt gcacagccac agtcattttt gatataatga ttcggaaatc ataaagaaaa
    11401 tggagaaagc ctatgaatat ttttgaagaa ctcaaagctc gtggcttggt ctttcagacg
    11461 accgatgaag aagcccttgt caaagcatta acagaagggc aagtatccta ttacactggc
    11521 tatgatccaa cagctgatag cctgcatctt ggtcatctcg ttgccatttt gacatcacgt
    11581 cgcttgcagc tagcaggaca caagccctac gctcttgtcg gtggggcaac tgggctgatt
    11641 ggtgatccgt cctttaaaga cgctgagcgt atcctacaaa ccaaggaaac cgttcttgat
    11701 tggagccaaa agattaaaga acaactctct tgctttcttg actttgacaa cggtgaaaac
    11761 aaggctgagc ttgtcaacaa ctatgactgg ttctcacaga ttagctttat tgacttcctt
    11821 cgtgatgtcg gcaagcactt cactatcaat tacatgatga gcaaggattc agtgaaaaaa
    11881 cgtatcgaaa ccggaatttc ctacaccgaa tttgcatatc aggtcatgca aggctacgat
    11941 ttttacgagc taaatgctaa gcacaatgtg acactgcaaa tcggcggctc tgaccagtgg
    12001 ggtaatatga cagcaggtac cgaattgctc cgcaaaaaag ctgacaagac tggacatgtg
    12061 atgacagtgc cattgattac agatgcaaca ggtaaaaaat tcggcaagtc agagggtaat
    12121 gcgatttggc ttgacgctaa aaaaacatct ccttacgaga tgtaccagtt ctggttaaat
    12181 gttatggacg atgatgcggt acgcttcctg aagatcttca ccttcttatc acttgatgag
    12241 attgctgcta ttgaggagca gttcaacgca gcacgccatg agcgccttgc tcaaaagaca
    12301 cttgcgcgtg aggtggtgac actggttcat ggagaggcag cctaccagca agccctcaat
    12361 attaccgaac agctttttgc aggagctatc aaaaaccttt cagcagctga gcttaagcaa
    12421 ggcttaagca atgtccctaa ctatcaggtt caagcagaag acagcctaaa tatcgtggat
    12481 atgttagtca cagcaggcat ttcaccatca aaacgtcagg cgcatgagga tttacaaaat
    12541 ggcgcgatct acctcaatgg agaacgactt caggatctgg attacagctt atctacagca
    12601 gatcgcattg acaatcagtt gaccgtcatt cgccgcggca agaaaaaata cgctgtacta
    12661 acctactaat cacagacagc taggaaaatc ttgctttgga tgattatttt tgacgtataa
    12721 aggacagcag gttaaccaca aggaagatcg caataaaaat catcgtaatg gtcgcacttg
    12781 ccggcgtttc ccaaaaatag gacaagaaaa taccagacag catgcctgta aagccaatca
    12841 taatcccaag aaaaataact gatttaaagt ttttcccaag ccgcatagca atacttgctg
    12901 gcaaaaccat aatcgttgat accaaaaggg cccctgccgc tgggatcgtt agagcaatag
    12961 caacacctgt cacaatatta aacaagacag acatgacacg caccggcaag ccatcgacgt
    13021 aggctgtgtc ctcatcgaag gtcaagatat acattggacg aataaataat atcgtcaagg
    13081 ctaaaataat caaagcaatg acaaataagg cagcaacctg ctccgtacta atagtaatga
    13141 tagagccaaa aaggtattgc tccaagctca tactagaaga gctagttgac ttactcatga
    13201 taatcaagga aatagccagc cccaaggaca ttaggatagc tgtcgaaatc tccatatagt
    13261 gcttataaac caccctaaga tattctagca agatggcagc tagcaccacc acaataatcg
    13321 ttgtgaaggt tggcgaaaca ccaagaacaa caccaaaggc cacaccagcc agagaaacgt
    13381 ggctaagcgt atcactcaac aagctttgac gacgcaaaat caaaaagata cccaaaatcg
    13441 gagcaaagat actgatcgcc acaacagcca taacagcacg ctgcataaaa tcataagata
    13501 aaatctcaag catggaatga ccctcctttg ctctcatcag cctcagcatc atgaatgttg
    13561 aagcaacgcc aaggaagccg ttgatttcta atcaaatgaa tattgcgatc agcataagcc
    13621 ttgacctcct ctgggtcatg tgtaatcatc aaaacagcct taccatgtct atgagcgctg
    13681 tggtgcatca actcataaaa agtatctgtt gttccactat ccattcctgt ggtcggctca
    13741 tcaagcacaa aaatatcggg gtcagaagca aacatacgcg caataaccac acgctgcttt
    13801 tgaccacctg atagactccc tattctctta tgccgactat cccacatgcc aacagactcc
    13861 aagcttgtcc gaacatgctc ctcatcgtgc ttacttagtc tggtaaacca accacttcta
    13921 ggatatctgc ctgatttaac aaattcataa acagtcgacg gaaagcctgc attaaagctg
    13981 gcaacctgct gtggcaagta agcaattctc agctttttcc catgaatgtt ctgtttagct
    14041 atagtcacct gcccagccct tggctttaaa atccccaagg tcgccttgat cagggttgac
    14101 ttggcagcac cattttcacc agtcaatgtg acaaattctc cactatccaa atgatagctg
    14161 attccctcta aaacaggctc actgtcatac tggaacgaga gattttccac cgatatgtat
    14221 ctcattatta cccttctaac tcctccgcaa aagcagtgat aaatttttca acaatcacct
    14281 gctcctccgc agaaaaatgt gccaacaaac gatgataaac agctagtgtt ttatcgtgat
    14341 gatgtgtatg ctccttagcg attggccttg ctagatcagt cagttcaaaa taggttactc
    14401 gagcatcaac ggtatccttt gttcctgcta gcatttcttg cttgatcaag cctttaatcg
    14461 ctttagttac tgctgcttga ctgatattta gcctttttgc caaatctgta ttggttagct
    14521 tttcctgtga caaaagcatc aaaatatgct cctgagtatt tgttaatttg acatcactct
    14581 gacaagcccc aaagagcagc tcatgctgat tttcagcctt taacaaaata cgattaacca
    14641 aattatcaag ctttttttct aaaattgtca tgatttccct ctcctcatta accagttaat
    14701 tataacatga cgccccaaaa gacgcaactt caaggctgat ctacagcgtt ctaaccttgt
    14761 agacttcctt acaaaagcct ttcaggctat tcaccacacg attggcctgc ttttctgttt
    14821 gacatagggc aaataccgtt ggaccacttc ctgtcatcag ggcaatgtct gctcctgact
    14881 gcagcatttt atccttaacc ttttgaataa acggccgttt agcaatggaa atatcctcta
    14941 aggaatttcc catcgttgca agcaagcgct gataatcacc tgcctcaatg gctgaaacca
    15001 gatcctcaat cggcactcga gatatcgtct cacaatcaat atcccaaaaa atcgttctag
    15061 tagaaatgcc aaattctggc ttcactagaa ccacccaaga ggacaagcgg ccattgattg
    15121 gcttaaccac ctcgcctttg ccagtcactt gggcgcagcc tgcaaaaaga caataaggca
    15181 catcgctacc aatctgcatg ccaatgtcaa tcatctgacg gggactaagc tttagctgcc
    15241 acagctgatt caatgctctg attgctgcag ccgcatcact tgagccacct cccataccag
    15301 cacaaacagg taccctctta tccaagaaaa tagagacacc tgttgagatt tgaaatcgct
    15361 ctttcagcaa ataagccgcc ttgtaaacgt cattgtgctc attaataggc aatctagggc
    15421 aattagaggt caataaaatc ctatcctcct ctaaatgatc cactgtaata taatcacaaa
    15481 gatctacact aactagaacc atagataggt catgatagcc atctggtcgc ttgccttgaa
    15541 tatctaagcc tagatttatt tttgcaggag ctctctcaat gattgcagtc ataatactcc
    15601 tttatttgat gtcattatag tatcaaatat acacaatctt catgaaaaat tcaaataaat
    15661 acagttagta tctaatgatg catagacagc gtgtttgtat caaaacagcc aaccatttgt
    15721 ccctactagc gtgaggcttc accagatcag cagccaaaaa acgacaacta ctagcatagc
    15781 aagcaaagct aagacagcag cagtctctat gaccacttga tcgctccata ttgccccact
    15841 aactcaaagc acatatcaat cttgctctta aagtagggaa taaaaatacc agcatcaatc
    15901 atggctaaaa tctcatcacg actagcccat cgaacagcct gtacctcctc tgtctgaaga
    15961 actagcttcc ttacatcaac agcctgcaaa atcaaaaaag tatcgtcaaa gccattatca
    16021 aaggtaattg aaaaatgagg ccttacacca gctaaatcaa gagtaagtcc tagctcctcc
    16081 ttcagttctc tcatcactgc ctcttgtgac gtctcacctg caagagcgct gccgcctacc
    16141 gttatatccc aatagctggg ccaaccctct ttatcctttt gccgctgctg aatcagcatt
    16201 tctcccttgt cattaaagac acaggcgtga accactaaat gataagcacc ctctacaaaa
    16261 gcagctccac gctccatgag tctaccagtc ttaagacgat tcatcgtata aatgtcccaa
    16321 tactcaacca tacaaacaca cctcctgata cagctattac cagatccagt atattaatca
    16381 tatcacaata agcatatcca aaacaaccag gtccagacaa aacaacaatt accaacctag
    16441 cttaattctt ttttctacaa ttccctacct taaaatgcct cgcatagaaa atggacaaaa
    16501 agatctgttt tcccgagacg tatcaaaaag ctcaccacgc taacaaactg gtagttaaga
    16561 tccccaagcg tcttactcag ttaacgatat ggtgatacac acagctgact tgcctcatca
    16621 tattagttac aaaaaacctt aaaggctcaa cccaaaagca caccaactac atcaccccat
    16681 gaaagaggaa gacaaaacat ctactgctgc aagcaaaaag agaccccatt agggcctctc
    16741 tagtgctcat atcagctttt aaactaatca atcgccttca agctaaaggc tatcatttag
    16801 taggagaaag ttgcaaaagc taatttagtt gttttttctt tttagagtta gcaggcctgc
    16861 gctggcaatg acgccgagag ctgcaagggt gaagaatggg tgatttgtct ctcctgtagc
    16921 tggtaatata cccttttgag ctgctggagc cgctgatttg cttggtgctg acttaggcgc
    16981 tggtacctta ggactagctg actgctgctc tgaagtcttt ggtacctgtg gagcaggaga
    17041 ttgctccggg gcctttggag ctgatggttt ggtatccttt ccttgctcgc ccttttcacc
    17101 gcgttggctt tgttcacc
//
LOCUS       DARYNN010000044        16704 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.044, whole genome shotgun sequence.
ACCESSION   DARYNN010000044 DARYNN010000000
VERSION     DARYNN010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16704)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16704)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16704
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.044"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            250..1962
                     /locus_tag="TVB59_001525"
     CDS             250..1962
                     /locus_tag="TVB59_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HEL1010402.1"
                     /translation="MQTLVISEKPSVAISISKVLGATKKKDGYNEGNGYRVSWCVGHL
                     IQMANPDAYDEKYAKWDMADLPIIPKDYKYEVAKATKKQFNILKKLMNDKEIDTVINA
                     CDAGREGESIFRLVYNQVNCKKKMKRLWISSMEDSAIKEGFDHLKDGKKYDNLFESAQ
                     ARAIADWLVGMNISRLYSCLYNQNYSVGRVQTPTLAMIVKRDDEIANFKKEKYYTVEL
                     SMDGFILSTDRIDDKVAAEQLINLVGDKIEITDVIQNEKITKPDLPFDLTTLQRECNK
                     YFGYSAKQTLDYAQSLYEKKLITYPRTDSRCLTEDMITSMINNILGQNDFDTGRIKVI
                     FNSSKVTDHHAIIPTVSSMSEDLLSIPESEAKVYGLIFNKLHASVGYPLIENTTKIVV
                     TFDGFKFTSSGKVIKDEGFTKYLKEYKTKKNEDIELPNVNIGDSLKIKDKEIKEKYTQ
                     PPKHFTENTLLKSMETAGNDALKKGIEVERKGIGTPATRAGIIENLIYKGFIQRDKKN
                     LVATHKGISLITIVADNFKSAETTAKWEMELSDISQGKSSKEEFLRRVEAEIRNELSR
                     YKKD"
     gene            1966..2517
                     /locus_tag="TVB59_001526"
     CDS             1966..2517
                     /locus_tag="TVB59_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014262113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEL1010403.1"
                     /translation="MFDTLIKFSKDREKLDFYATDKRAIHELLKREQFLSPIYEPACG
                     MGHIGKVLEEYGYKVKATDICYRGYGEEREVDFFTVTENILDIVTNPPYFCASEFLRH
                     ALEISGPKVKIAMLFRLAFLEGQSRYELFRKYPPKRVYVFSKRLNCAKNGEFEKYKSS
                     AIAFAWFIWEVGYKGITELRWIR"
     gene            2559..3305
                     /locus_tag="TVB59_001527"
     CDS             2559..3305
                     /locus_tag="TVB59_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1010404.1"
                     /translation="MDKNEVLQSQENQTKEVMQEIKEEYTKTADFLEEHINQQLVIAK
                     EMKEEMQNKDFDVNIKELKALKEEITGLKAEIKRLNEMENITFGSLIIRDIKSVGNTL
                     INLQEKAVGSIKHLYDNMKHQLSYNLTKAQEKFVQMKIGIVKGLVNSMQDFIKDQQKK
                     LDSCLAKLDNLSKEIQKDEEKLEKGNLNKEKTLIKKREQSIEEKESQKEKMEKKPSVL
                     KKLKENQQKIKQEEKNKDIKALKKDKGMEL"
     gene            5126..5617
                     /locus_tag="TVB59_001528"
     CDS             5126..5617
                     /locus_tag="TVB59_001528"
                     /inference="COORDINATES: protein motif:HMM:NF025561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TnpV protein"
                     /protein_id="HEL1010405.1"
                     /translation="MKKKEMKEVWKMKETVVLAKKEYILENEIYTPIVKESPFERQGG
                     TYRLEKMEDGAEVLVPNMKMPEKINASKLNRFGKERLKYLKEEKQEEYQIMLMEETLM
                     DHLIDIQEQVEDFLNIEEPRMKEAWKMTTEMQDQDFLKYTGLKKNLDMTLTKMAMEQI
                     IWV"
     gene            7831..15249
                     /locus_tag="TVB59_001529"
     CDS             7831..15249
                     /locus_tag="TVB59_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003035833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEL1010406.1"
                     /translation="MKEVNLTDLNDVFYLENQGLYEISSDRVTEEKAGYDFEVASFNE
                     QFPDYYNDIYVYNRNLKIDGANQNIAYINRENEIHFNVNLPEEEKAKVLEIRDKKEVL
                     STLIFKDVKEVGEYQFHPQSEEFILNELSISEEKLKAPEHITDKIDKKEGYEAELVLD
                     MKNKELRQHLRYNGYMLSSNVAVSYDSYKAILKNLSYLLDDNHRNIMLTGYVNEQIEK
                     DKAKEERKEPVYQEGMNVRYQGKEYIISEIQDYKTYKTIKLDDSEGYLNGFITGSEII
                     PFRNERELDLEIISTTEKLQEQSINGEDLILLDIEEYNKKGLSVIFQNKEYEITGNNF
                     NPVGMSRLQLVSNTEKLMTEISYTPQRPVANLYAKKDLLERFNLNEKNSEKSIEAKQM
                     SLTDIFEEQDTTKGKEEISSEKERVPVNIGAKVIYQGEEYTVSAFEYNNILEKNDIWL
                     NPVSKNNHQIPIVSFSDREELNEKLIVIDTNLNLGEDKSELLHHSLDVINDKGSVIAN
                     QFIVKVDNQNRELTVYSEQNPNSHREFELSFDYLNGLGQIDGDGNNLKLTKHKKETID
                     KKLKSYHSWKEDGEKRGIPGIAGSSITSPITDEMFWQMKEYEEKLKEEERYAPDDKYL
                     GGIPPINYKITKEDEILPPSERLKNNIEAIKVLKEIEERHSHATKEEQDILSRYVGWG
                     GLSDVFDEEKGGQWKDAREFLKENLSPSEYDAARESTLTAFYTPKIVIDSIYQAVLNM
                     GFESGNILEPSMGTGRFIGNLPDSMKGSKFYGVELDSISGRIASRLYPNAKIQIKGFE
                     ETTFSNNLFDVAVGNVPFGEYKIVDREYEKNNFLIHDFFFAKTLDKVRSGGVVAFISS
                     SGTMDKKSEDIRRYISERAEFLGAIRLPNNTFKGEAGTEVTSDIIFLKKRDRLVKLDE
                     EWVKLGTDERGLTYNKYFVDNPDMVLGNMEEISSRFGTSLACVADENSTLKEQLDTAI
                     KNIKGSYEKIELNNEFEVETIPADDSVKNYSYAVIDDKVYFRENSVMQKLNLNKNDEE
                     KVRAYLGIEKALRQVIAYQKEDYSDTEIKEKQGELNRIYDEFSKKYGILNSKANKKLF
                     REDANYSLLSTLEKLDKEGNFIEKSDIFTKRTIKKAVAIEHTDNLTEALILSISQKGK
                     VNFEYMEKLTEKTRGEIIEGLKGEIFLNLDGFDPSDTTPFSSAIDLGDFSRSYVTADE
                     YLSGNIRDKIEVIDSYIKNVEHEFEQNEQLENIDADVLKQGSETLKKELSSLNYQRQK
                     LLEVMPKELEASEITVRMGATWIPEKDYKSFMFHLLKTSASNRWNIDIKYTNFTGEYR
                     VEGKSIDKGNDLANFTYGTSRVSAYKLIEDTLNLRDTNVYDQVIDENGKKSSVLNQKE
                     TMLARSKQEIIKEEFKNWIFDDIDRRTRLVKEYNEKFNSIRLREYDGSNLTFDGMNPE
                     IELRPHQRDAIARGLFGGNTLLAHEVGAGKTFEMIGIAMESKRLGMSNKSMFVVPNHI
                     VEQFGREFNELYPAANILCATEKDFTPDKRKRFCSRIATGDYDAVIIGHSQFEKIPIS
                     KQRQEYELQSQIDEIIDFIEEYKRNRDQKFTVKQLEKTKKGLEAKLKKLNDDYRKDDV
                     VTFEELGIDKLFVDEVHAFKNLYVFTKMRNVAGITTTDSQKSSDMLMKCRYMDEITGN
                     KGIVFATGTPVSNSMAELYTMQRYLQYDELKKMHLQHFDSWASTFGETVTAIELNPEG
                     NGYRSKTRFAKFYNLPELMNMVKQFMDIKTADVLNLPVPNAHYETIKTKPTEEQKQIL
                     ETFSERADKVRGKQVDSSVDNMLLITNDGKKMALDQRLINPLLPDDPNSKVNTCVNNI
                     FSIWDKYRDEKSTQLVFCDMSTPSSEFNIYDDIKEKLTKMGIPKNETEFIHNAKNNKE
                     KDKIFDKVRKGEIRVLLGSTQKMGAGTNAQNKLIATHDLDVPWRPADLEQRKGRIVRQ
                     GNENDDVHIFRYITENTFDAYLFQTLETKQTYISQIMNSKTPVRVAEDIDEATLNYAE
                     IKALATGNPLIREKMDLDVEVSKLKMLESNFKSNLYKMEDKVVKVYPKEIKSLKEKIE
                     NLKKDIEKVEPYREEKLEKYDQTTLENMGENEKQVGIKADKEAISKFTSLTLNGKKYT
                     DKKQAGEFLINKIKGIKKLDDFRSEEVKIGEYRNFDLFAYYDRFSNQYKFNLKGEENH
                     YGEFGTDEIGNITRMDNVLDRMPERLEQTLGKLKDTENQLETAKLEIKKKFPQAELLK
                     EKTLRLAEVNNLLDMGQKGDLKEEKNPLLEEVKEELIHFLNKEYDEAHSIEDFDTMFP
                     DLTDIGLAYTTTPDEKHEIQTSLDLINYKMNTYVDNTLIDSFQYTYDPLNASDTKELI
                     QIKTNIGFWDFNELVYVDEEKLKASLGLEIDDDGNFYDPLSKDMDLDGVMDRYDADFR
                     DSKVQSFGDLDKKEKASVMDRLGYFKEKIKKGGLQNENIDRKIECKEEVR"
     gene            15730..16689
                     /locus_tag="TVB59_001530"
     CDS             15730..16689
                     /locus_tag="TVB59_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014262110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL1010407.1"
                     /translation="MKLEKGDIVKTALSENTTVLDVKDNQAVLFSGTQFVLATGIKEN
                     KESGKFEWDNGRYANDLKSISDIQNNNFETMKETLSFLAEYNHSDFVKGILSLETGIE
                     NEDTLDAAYDNYMNDKIMGLVDEKFYHYIDENEIEAPDLESEIQDKNSVLSDEENVKE
                     DNNTTSEKSNENKEKANTVNINGNIASDIDIKNLTSKDGRDFTVASFAVAENDKEGNV
                     KYTNCLAYNDKVSSVENLKKGDFVHVFGKEKISQGKDGKEYTSLKVYSAKLLKAKEQS
                     KTNQNAKDVKKPSALGKLKEYKEKAGEKSKEQVSVKKDKNIER"
BASE COUNT         6807 a         2004 c         3488 g         4405 t
ORIGIN      
        1 tatgcgaaag atataacttt tgaagaagta ttggacaacg gaataaaaat ggtggaaaaa
       61 ataaagaatg aaaattagca tataacggtt ttacaatgaa aagaaggcgt caaacatttt
      121 tttgtaagtt agttcccaaa caggaaaatg gattaaaaaa tagaaaatga aatatataaa
      181 actttaaaag acaattggag aaatgcaaac tctgattgtc ttttttcatg tagaaaaaag
      241 gaggaattta tgcaaacact ggtgataagt gaaaaaccga gtgttgcaat aagcatatca
      301 aaggtgcttg gagcaacaaa aaagaaagac ggatataatg agggaaatgg atatagggta
      361 agttggtgtg ttggtcattt aattcagatg gcaaatccgg atgcttatga tgaaaagtat
      421 gccaagtggg atatggctga tttaccgatt attcccaagg actataagta tgaagtagca
      481 aaggcaacca agaagcaatt caacatcctt aaaaagctga tgaatgataa agaaattgat
      541 acggttataa atgcttgcga tgcaggtcgt gagggagaga gcatttttag acttgtttat
      601 aatcaagtga attgtaaaaa gaaaatgaaa cgcctttgga tttcatctat ggaagatagt
      661 gcgattaaag agggttttga tcatctaaaa gacggaaaga aatatgacaa tctctttgaa
      721 tcggcacagg caagagccat tgcagattgg ttagtcggaa tgaatattag tagactttat
      781 tcctgcttat ataatcaaaa ttactctgtc ggtagggtgc agacgccaac tcttgccatg
      841 attgtaaaac gagatgacga gatagcaaac tttaaaaaag aaaaatatta tactgtagag
      901 ctatctatgg acggttttat actttccaca gacagaattg atgataaggt agcagcagag
      961 cagctaatca atttagttgg tgataagatt gaaattaccg atgtcattca aaatgaaaag
     1021 attacaaagc cggatttacc ttttgacctg acaacacttc aaagagagtg caataaatat
     1081 tttggatact cagctaagca gactcttgat tatgctcaaa gtctgtatga gaagaaactt
     1141 attacctatc caagaacaga cagtagatgc cttactgaag atatgattac aagtatgata
     1201 aataacatat tgggacaaaa tgactttgat acagggcgta ttaaggtcat ttttaattca
     1261 agcaaggtaa cggatcatca tgctattata ccgacagtaa gttcaatgag tgaagattta
     1321 ttgagtattc cggagagtga agcaaaagtg tatggactta tttttaataa gttacacgca
     1381 agtgtgggct atcctttaat cgagaataca acaaagattg tagtgacttt tgacggcttt
     1441 aaatttacaa gttccggaaa agtaattaag gatgaggggt ttactaagta tttaaaggaa
     1501 tataagacga aaaagaatga agatatagaa cttccaaatg taaatatagg tgatagtctt
     1561 aaaatcaagg ataaagaaat caaagaaaaa tatacgcaac ctccaaaaca ttttacggaa
     1621 aacaccttat taaaaagcat ggaaacagca ggaaatgacg ctttaaaaaa aggtattgag
     1681 gttgaaagaa agggtattgg cacacccgca actcgtgcag ggattataga aaatctaatt
     1741 tacaaaggct ttattcaaag agataagaaa aatcttgtag ctacacataa aggaattagt
     1801 cttataacaa ttgttgcaga caactttaaa tctgctgaaa caactgcaaa gtgggaaatg
     1861 gagttgtctg atatttctca agggaaatct tcaaaggaag aatttttaag aagagtagaa
     1921 gctgagataa gaaatgaatt atcccgttat aaaaaggatt agtctatgtt tgatactcta
     1981 ataaaattta gtaaagacag agaaaaattg gatttttatg ccacagataa aagggcaatt
     2041 catgaacttt taaaaagaga gcagtttcta tctcctattt atgagccggc ttgtggaatg
     2101 gggcatatcg gaaaagttct ggaagaatac ggttataagg taaaagctac agatatttgt
     2161 tataggggat atggagaaga aagagaagtt gattttttta cagtaacaga aaatatattg
     2221 gatatagtaa ccaatccacc atatttttgt gcaagtgagt ttttaaggca cgctcttgaa
     2281 atatcaggac ctaaagtaaa gatagcaatg ctatttcggt tggctttttt ggaaggtcaa
     2341 tcaagatatg aattatttag gaaatatcct ccaaagagag tatatgtatt ttccaaaagg
     2401 cttaattgtg caaaaaacgg agaatttgag aaatacaaaa gcagtgctat tgcctttgcc
     2461 tggtttatat gggaggtggg atacaaaggt attacggagt taaggtggat tagataaaag
     2521 gatggaataa aacaactgaa aaaacgaagg aggatagtat ggataagaat gaagtattac
     2581 aatcacagga aaatcagaca aaggaagtta tgcaggagat taaagaggaa tataccaaaa
     2641 cagctgactt tttagaagaa catataaatc agcagcttgt gattgctaag gaaatgaaag
     2701 aagagatgca aaataaggac tttgatgtaa atatcaaaga attgaaagca ctcaaagaag
     2761 aaatcaccgg attaaaagct gaaattaaac gattaaacga aatggaaaat ataacttttg
     2821 gttcattgat tataagagat atcaaatctg taggaaatac ccttatcaat ttacaggaaa
     2881 aagcggtagg aagtattaaa catctgtatg ataatatgaa acatcagctt tcctataacc
     2941 ttaccaaagc acaggaaaaa tttgtacaga tgaaaatagg aattgtaaaa ggattggtaa
     3001 attccatgca ggattttatc aaggatcaac aaaagaaact ggatagttgc ttagcaaaac
     3061 ttgataatct atctaaagaa attcaaaaag atgaagaaaa actggaaaaa ggcaatctga
     3121 ataaagagaa aaccctgata aaaaaaaggg aacaaagcat agaggaaaaa gaaagtcaaa
     3181 aggaaaagat ggagaaaaaa ccgtctgtgc taaaaaaatt aaaggaaaat cagcaaaaaa
     3241 tcaagcagga agaaaagaat aaagatataa aggcacttaa aaaagataag ggaatggaac
     3301 tataaaaaag aggtggtagt tatgaatgac ctcataaaaa actatgaaaa tattcctgat
     3361 gagatgaaaa aagagaagcg ttggtgccta tataaaatca ttcaaagaga cgggaagaac
     3421 acgaaacttc cactaatgcc aaataaagag ccggcaaaat caaatgataa agctacatgg
     3481 aatagctatg aggattgtat catggcatta aaacataatg ttggcgaagg gcttggcttt
     3541 ttcttaggag atggatacat tggaatagat attgataaag taagtgatga cattatggag
     3601 tacaatacga atcatcatgt aagctctatg acggctgatt ttttaagaga agtttccacc
     3661 tatgctgaga tttctccatc gaaaacagga ctacatttta ttggaaaagg agaggtgccg
     3721 ggagaaagaa aaagatataa aaatcttgaa atttatgata aggataggtt ttttacagtt
     3781 accggtaatg ttataaagga tagagatagg agcaaaatag aaagtattga cagtgagcta
     3841 aagcccttat atgaaaaata tatgccaaag acaaataaaa ttagtgctga aaataaaaga
     3901 agtccaacgg ttacttctta caatggggat caggacatat tagaaaagtt atttgacagg
     3961 ggatattttt catatgcagg agaagattta agacaaattt actatggtaa ttatgaacgc
     4021 tattttaaca gccaatcgga ggctgatttt tttatgctac aaaggctgct ttactataca
     4081 ggaaatgtag aaatggcaat atcatttatg gaaagtagcg gactgaaaag agaaaaatgg
     4141 tataaaagac gaggcaatac cgattatatc cactatattg cagataaggc gataagctct
     4201 atcaatcaat tttatgattg ggaaaaagta tatacatcaa aggaaaaaat agaagaaaaa
     4261 agatatgaaa ataagaagaa aaaggaggga gatacagtgc caagatatga atttgatgaa
     4321 gtcaaacaga ttcttgattt tgcaaaagaa gaatttaaag aaaatataga caggtatgaa
     4381 acttatctca aagtgatggg aaataactat aaatatccgt actttaacca gcttagcata
     4441 tatacggtaa atgaaaatgc aactgcttgt gcagaatatg actattggaa aagtatagga
     4501 agaaatgtaa atagaggaga aaaaggaata cctgttttag acattgaaag agagaagata
     4561 aagtatatct ttgatgcaag tcagacagta agtttaaatc acaacatttc tgaagtaaag
     4621 ttatgggaat atagcaataa taagcatgta gctgccttag atactcttat cgatgttttc
     4681 aaagaaaaaa acagtaacct tatattttct actgaagata agataaatac aatcgtttca
     4741 ctatatacaa agcaattact aaataaggta cttaattctt taagtgatga aactttaaag
     4801 gaaaataaga aagtacaaat tcttcatttt ttggaagaat ctgcaaaagt atcggtatat
     4861 gagagaatgg gagttgcatt ttccggtgat atagaaaaat tagagatgct ttcaaatgtt
     4921 tcaagtatgc aggatattga cagattactt ttctttactt caaacaatgt aaaaagaata
     4981 cttatggata taagtagaga aatttcaaaa gtggaagaaa gagaaaaaat ttcagaaatt
     5041 caaaaaaggg agcagacaaa tagtattgcg gagcgttata ctaatgttac agatgaaatt
     5101 aacggaaata ccgaaattat agaaaatgaa aaagaaagaa atgaaggagg tttggaagat
     5161 gaaagaaacc gtagtattgg cgaagaagga gtacatccta gaaaacgaga tttatacacc
     5221 gatcgtaaaa gagagtccat tcgagagaca gggagggact tacagattgg agaaaatgga
     5281 ggatggagcg gaagtattag ttccgaatat gaaaatgccg gagaaaataa acgcaagcaa
     5341 actgaaccga tttggcaagg agagactgaa atatctcaaa gaggagaaac aagaggaata
     5401 tcagattatg ctgatggaag aaactttaat ggatcatttg atagatattc aggaacaagt
     5461 ggaggatttc ctgaatatag aagagccgag gatgaaagaa gcttggaaaa tgaccacaga
     5521 aatgcaggat caggactttc tgaaatacac aggactgaag aagaacttgg atatgacact
     5581 aacaaaaatg gctatggaac agatcatttg ggtatagatg agtatcgtaa agaaaatata
     5641 cagaagatag aacaaaatca tgtagaaaat gaggaaaaag aagtcgagag gacttctttt
     5701 tcttttgctc aaaatgtagg agttcaagga agatttgaat taccaatgca gcaagaagag
     5761 attggtgctg ttttaattca tggaggaaat gaggataatt tacatttaaa ggttttagcc
     5821 gaatattcta aagaaaaaag catggaagaa ttagctgatt ttcttcaaaa aacttttcaa
     5881 ggaggaaatg gatatgaact aaatggaaat aaggtttgtg cttggtatga aatggacggg
     5941 atacatttat ccaatgatgt ttcctcaaga gaaaatccta tgcagatttt accatggaaa
     6001 gatgcagcaa tacgcatagg agaattgatt gattatggaa aatacagtac aaatgtggag
     6061 gtagcagaag ccttttcttt tgaaagagca gaactttctg aaaagctgtg gtttttaaaa
     6121 ggagatctaa gtgatgaggt aaaaaatcag tttttgccaa ttctaaatga aaaacaaaga
     6181 aacggatatc ctgaaaaaac agagtatctt acaaaaaaat tggaagataa agagtttaga
     6241 gtgaacttaa aagaggagta tatagagttt tttaaggcgt ataaggagaa ctcgaatgtt
     6301 ttaagatttc ataatcatga tttagatgat atatcaaaac gattagatga tttggaactg
     6361 ccaagaaaag aatttacctc aacacttata gaattaccag caatacaggg atttatcaca
     6421 gaagatgaaa ttgatagata tttaagcagc ggtagcaatg tatccggcgg aaaagaaaga
     6481 atatataact tttttaggga agcccatact accgaagaac gagcaaattt tttaaaagac
     6541 gagtacggaa caggaggaca gactcatgct ttatcaaggg caagaggaag tagtgagtgg
     6601 cacgatgcta aggggataaa acttgaaaaa gaaaattgta aggatattat tttgaaatgg
     6661 aatcaggttg taaaaaaaat agataacctt attgaaaatg gaaaatatat tcaagaagat
     6721 gtatatacag agcaagaaag cataaaaact gaggaagaat attttgatga agatacctat
     6781 acggaacaaa actctaaaga aaatgaacaa gattggcaaa gagaacagga aattttgctg
     6841 attcaagatg aaagagaagt atcttatgaa gaggcggagg aaatatatga aaggcaagca
     6901 gaaatagaac ataatgcctt tgcaaccggt gtagagaata acatatcgtc aactcaaagt
     6961 aacaaggatt attggattgt agaatttaat gaaggctcaa atctgataga aaaaaattat
     7021 gccggagaag ttgttacgaa aaaattgctt gatgaaatca aggtgcttga cgaaaaaatt
     7081 agagttcata ataagactgt cggtgaagat gaatacggag aaatgacaga tgaatgggta
     7141 ggttattcta aattctattt tgaccatatt gtagacggga aagtagaaga acacttcaga
     7201 atggatatcg gggatggaaa tgaggtaaac caaagagatt ttcaatatct ttatgagcag
     7261 attgaaccgg aaaaagaaaa taaagaatac gggatggata gtatagatag tgtcataaaa
     7321 gatattttag aaaaagaatc tatgactgtg gtatcaagca aagatgatta tataaagtta
     7381 tttccatatt ttagaaactt tgtatatacc gatggtctaa ggcttgatga atataatccg
     7441 tttgaagatg atgaaaatat ttcggattta attcgactga cttttttcca aaataatgat
     7501 ggagaatata gggtagtcta taacaatgcg gacagtttac tgtattcaag caatgttgac
     7561 tattttttgg agaaaataga ggctgaaaag gtaaggttag aagataatat agctgagata
     7621 ccgaatgaag ataaaattgc cgttaaggtt gggaattact atgctgttgt agaaaaagaa
     7681 agagtaaagg atatatcctt agaagaaaca ggagttcgtg tttatccgaa agaaaataac
     7741 tttgagggaa aaatttaccc attgtatcgt ggcagcacct ttgaagaaag tgcaaaaata
     7801 gataaacttt tcgatgagat tgcaataggc atgaaagagg tcaatttgac cgatttaaat
     7861 gatgtttttt atcttgaaaa tcaaggactt tatgaaattt catcggatag ggtaacggaa
     7921 gaaaaagccg gatacgattt tgaagtggca agttttaatg aacagtttcc tgattactat
     7981 aatgacattt atgtatataa cagaaattta aaaatagatg gtgctaatca aaacattgca
     8041 tatatcaata gagaaaatga aatacatttt aatgtaaatc taccggaaga agaaaaagca
     8101 aaggtgcttg aaattagaga taagaaagaa gtcttatcaa ctcttatttt taaagatgta
     8161 aaggaggtcg gcgaatatca gtttcatcca caaagcgaag aatttatctt aaatgaattg
     8221 agtatatctg aagaaaaatt aaaagcaccg gaacatataa cagataagat tgataagaaa
     8281 gaaggctatg aggctgaact tgttttggat atgaaaaaca aggagttaag gcagcattta
     8341 agatataacg gatatatgtt aagtagcaat gtggcggttt cctatgatag ttataaagca
     8401 atacttaaaa atctttctta tctgcttgat gataatcata gaaatattat gcttaccggc
     8461 tatgtcaacg aacagattga aaaggataaa gcaaaggaag aaagaaaaga acctgtatat
     8521 caagagggaa tgaatgtaag gtatcaaggc aaagaatata tcatttcaga aattcaagac
     8581 tataaaacat ataaaacaat aaagctagat gattcagaag gatatttaaa cggctttata
     8641 acgggcagtg aaattattcc ttttagaaat gaaagagaac ttgatttgga aatcatatct
     8701 acaacagaga agttacaaga acaaagtata aatggtgaag atcttattct gttagatatt
     8761 gaagaatata acaaaaaagg actttccgtt atctttcaaa ataaagagta tgaaattaca
     8821 ggaaataatt ttaatcctgt aggaatgagc aggttacaac ttgtctcgaa tacagaaaaa
     8881 ctgatgacag aaatttcata tacacctcaa agaccggtcg caaatcttta tgcaaaaaaa
     8941 gatctccttg aaaggtttaa tttaaatgag aaaaatagtg aaaaaagtat tgaagcaaag
     9001 caaatgtctt taacagatat atttgaggaa caggatacaa caaagggaaa agaagaaatt
     9061 tcaagtgaga aagaacgtgt acctgtcaat ataggggcaa aggtaatcta tcagggagaa
     9121 gaatatacag taagtgcctt tgagtataat aatattttag agaaaaatga tatatggcta
     9181 aatcctgtat caaaaaataa tcatcaaatt ccgattgtaa gtttttctga cagagaagag
     9241 ctaaatgaaa agctcattgt tatagatacc aatcttaact taggagaaga caagtcggaa
     9301 ctgttacatc atagtttaga tgtaataaat gataaaggtt ctgtgattgc caatcagttt
     9361 attgtaaaag tcgataatca aaacagggaa cttacagtat atagtgaaca aaatcctaat
     9421 agtcatagag aatttgaact ttcttttgat tatctaaacg ggcttgggca aattgacgga
     9481 gatggaaata atctaaaact tacaaagcat aaaaaagaaa ccattgataa aaaattgaaa
     9541 agttatcatt cttggaaaga agatggggaa aaaagaggaa ttccgggaat agcaggttct
     9601 tctattactt cacctattac tgatgaaatg ttttggcaga tgaaagaata tgaagaaaaa
     9661 ttaaaagagg aggaaagata cgcccctgat gataagtatt tgggaggtat tcctccaatc
     9721 aattacaaaa tcacaaaaga agatgaaatc ttgccgccgt ccgaaaggct taaaaataac
     9781 atagaagcca tcaaggtatt aaaagaaatt gaggaaagac atagtcatgc aacaaaggaa
     9841 gaacaggata ttttgagtag atatgtcggc tggggtggac tttctgatgt ctttgatgaa
     9901 gaaaagggag gacaatggaa agatgcaaga gaattcttaa aagaaaatct atcaccgtct
     9961 gagtacgatg cagcaaggga aagtaccctt acagcctttt atacaccgaa gattgtaata
    10021 gacagtatct atcaagccgt attaaatatg ggatttgaaa gtgggaatat cttggaacca
    10081 agtatgggaa ctggcagatt tataggcaat cttccagaca gcatgaaagg cagtaaattt
    10141 tatggtgtag aacttgacag tataagtggt aggatagcaa gtaggctata tcctaatgct
    10201 aaaatacaga tcaaaggttt tgaagaaacg actttttcaa ataatctgtt tgatgtagcg
    10261 gtgggaaatg taccgtttgg agaatataag atagttgatc gtgagtatga gaaaaacaat
    10321 tttcttattc acgatttttt ctttgccaaa accttggata aagtacgttc cggtggagta
    10381 gtagccttta taagttcaag tggaactatg gataaaaaga gtgaagatat cagaagatat
    10441 atttcagaaa gagcagagtt tttaggagca attagactac ctaataatac ttttaaaggc
    10501 gaggcgggta cggaagtaac aagtgatatt atttttctta aaaagagaga tcgactggta
    10561 aaacttgatg aagaatgggt aaaacttggc actgacgaaa gaggactgac atataacaaa
    10621 tactttgtag ataaccctga tatggtactt ggaaatatgg aagaaatatc aagcagattt
    10681 ggaacaagtc ttgcctgtgt tgcagatgaa aatagtactc tgaaagaaca gctggatacc
    10741 gccattaaaa acattaaagg aagttatgag aagatagaat taaataatga atttgaagtg
    10801 gaaaccattc cggctgatga cagtgtgaaa aattattctt atgcagtaat tgatgataag
    10861 gtatatttta gagaaaattc cgttatgcaa aaattgaatt taaataaaaa tgatgaggaa
    10921 aaagtaaggg catatcttgg aatagaaaaa gcattaagac aggtaattgc ttatcaaaaa
    10981 gaagattatt ccgatacgga aattaaggag aagcaagggg agttaaatcg tatttatgat
    11041 gagttttcca agaaatacgg aattttaaac agtaaggcga ataaaaaact gtttcgtgaa
    11101 gacgctaatt attctttact gtccactttg gaaaagctgg ataaagaagg aaactttata
    11161 gaaaaatccg atatctttac aaaaagaaca ataaaaaaag cagtagccat agagcatacc
    11221 gacaatctga cagaagcact tatcctatct atttctcaaa aagggaaagt caatttcgag
    11281 tatatggaaa agctcactga aaaaacaaga ggagaaatca ttgaaggatt aaagggagaa
    11341 atattcttaa atttagatgg atttgatcca agtgatacga ctcctttttc ttcagccata
    11401 gacttgggag atttttcaag atcttacgta actgctgatg aatatttatc tggaaatatc
    11461 agagataaaa tagaagtaat agattcgtat ataaagaatg tagaacatga atttgaacaa
    11521 aatgaacagc ttgaaaatat tgatgcagat gtactgaaac agggtagtga gactttaaaa
    11581 aaagaactgt ccagtttaaa ttaccaaaga caaaagctgc tagaagtaat gccaaaggag
    11641 cttgaggcaa gtgaaataac cgttagaatg ggagcaactt ggatacctga gaaagattat
    11701 aagagcttta tgttccatct tctaaaaaca tcggcatcta atagatggaa tattgatatt
    11761 aaatatacca attttacagg ggagtacaga gttgaaggta aaagtataga taaaggaaac
    11821 gaccttgcca atttcacata cggaacaagc agagtaagtg catataaact gattgaagat
    11881 acattaaacc ttagagatac caatgtatat gatcaagtca ttgatgaaaa cggaaagaaa
    11941 agttctgtac taaatcaaaa agaaacgatg cttgcaagaa gtaaacagga aattatcaaa
    12001 gaagagttta aaaattggat tttcgatgat atagacagaa gaacaaggct tgtaaaagaa
    12061 tacaatgaga aattcaattc gataaggctt agagaatatg atggaagtaa tttaactttt
    12121 gacggaatga atcctgaaat agagcttaga cctcatcaaa gagatgcgat tgctagagga
    12181 cttttcggtg gaaacaccct acttgcacat gaagttggag ctggaaagac ttttgagatg
    12241 ataggaattg ctatggagtc taaaaggctt ggaatgagta acaagtcaat gtttgtagtt
    12301 ccaaaccata ttgtagaaca gtttggtaga gagtttaatg aactgtatcc ggcagcaaat
    12361 attctttgtg caacagaaaa agactttaca ccagataaaa gaaaaagatt ttgctcaagg
    12421 attgcaaccg gtgattatga tgcggtaatt atagggcatt cgcagtttga aaagattcca
    12481 atttcaaagc agcgacagga gtatgaactt caaagtcaga ttgatgaaat tatagatttt
    12541 atcgaagaat ataaaaggaa tagagatcag aaattcaccg ttaagcagct tgaaaaaacg
    12601 aaaaaaggac tggaggcaaa actaaagaaa ttaaatgatg attatagaaa agatgatgtc
    12661 gtaacctttg aagaattggg gatagacaag ctatttgtag acgaagttca tgcttttaaa
    12721 aatttgtacg tttttacaaa aatgcgtaat gtagcaggaa ttacaaccac agattctcaa
    12781 aaatcaagtg atatgctgat gaagtgcaga tatatggatg aaattaccgg taataagggt
    12841 attgtatttg cgacaggaac ccctgtgagc aattctatgg cagagcttta taccatgcag
    12901 cgttatctcc aatatgacga acttaaaaaa atgcacttgc aacactttga ttcttgggca
    12961 tctacttttg gagaaactgt tacagcaatt gaacttaatc ctgaagggaa cggatatcga
    13021 agcaagacaa gatttgcaaa attttataac cttccggaac tgatgaatat ggtcaagcag
    13081 tttatggata taaagactgc tgatgtatta aatcttcccg ttccaaatgc tcattatgaa
    13141 acgataaaaa ccaaaccgac agaagaacaa aaacaaatcc ttgaaacttt ttctgagaga
    13201 gctgataagg ttagaggaaa acaggtggat tcctctgtcg ataatatgct tctgattact
    13261 aatgacggaa agaaaatggc acttgaccaa aggttaatta atccattact tcctgatgat
    13321 ccgaacagta aagtaaatac ctgtgtaaat aatatattca gtatttggga taaatatagg
    13381 gatgagaagt ccacacaatt agttttttgt gatatgtcaa caccatcaag tgaatttaat
    13441 atttatgatg atataaagga gaagctgaca aaaatgggga ttcctaaaaa tgaaacagag
    13501 tttattcata acgcaaagaa caacaaagaa aaagataaga ttttcgataa ggtacgaaag
    13561 ggtgaaattc gtgtgcttct cggttcaacg cagaaaatgg gagcagggac aaatgctcaa
    13621 aataaattga ttgctaccca tgatctcgat gtaccctgga ggcctgcgga tttggagcag
    13681 agaaaaggaa gaattgtaag gcaaggtaat gaaaatgatg atgttcatat ctttcgttat
    13741 attacggaaa atacctttga tgcgtatctt ttccaaacac ttgaaaccaa gcaaacttat
    13801 atatctcaaa taatgaattc aaagacacct gtaagagtag cggaggatat tgatgaagct
    13861 acattaaatt atgcggagat taaagcactt gcaacaggaa atccgcttat tcgtgaaaaa
    13921 atggaccttg atgttgaggt aagtaaactt aaaatgctgg agtccaattt taaatccaac
    13981 ctatataaaa tggaagataa ggttgtaaaa gtatatccaa aagaaattaa aagtctaaaa
    14041 gaaaaaatag aaaatttgaa aaaggatata gaaaaagtgg aaccgtatag ggaggaaaaa
    14101 ctagaaaaat atgatcagac tactttagaa aatatgggtg aaaatgaaaa acaagtgggg
    14161 ataaaagcag ataaagaagc aatatcaaaa ttcacatctt taactttaaa tgggaaaaaa
    14221 tataccgata aaaagcaagc cggagagttc ttaataaaca agataaaagg aataaaaaaa
    14281 ttagatgatt ttcgttctga ggaagtaaaa atcggagaat atagaaattt cgatttgttc
    14341 gcatattatg acaggttctc caatcagtat aaattcaatc tgaagggaga agaaaatcat
    14401 tatggggagt ttggaacgga tgaaatcgga aatatcaccc gaatggataa tgtacttgat
    14461 aggatgcctg agagattgga gcagacactt ggaaaactta aagataccga gaatcaactt
    14521 gaaacggcga agcttgaaat aaaaaagaaa tttccacagg cagagctttt aaaagaaaag
    14581 acgttaagac ttgctgaggt aaataatttg cttgatatgg gacaaaaagg agatttaaaa
    14641 gaggagaaaa atccactttt ggaagaagtg aaggaagaac tgattcattt tctaaataaa
    14701 gaatatgatg aagcacacag tatagaagat ttcgatacaa tgtttcctga cttgacagat
    14761 ataggtttgg catatacgac tacaccggat gaaaagcatg agatacagac aagtcttgat
    14821 ttaatcaatt acaagatgaa cacttatgta gacaatactt taattgacag ttttcagtat
    14881 acttacgatc cacttaatgc aagtgatacg aaggaactta tacaaatcaa aacgaacata
    14941 ggtttttggg attttaatga gctggtatat gtggatgaag aaaagttaaa agcatcactt
    15001 ggacttgaaa ttgatgacga tggtaatttc tatgatccgc tttcaaagga tatggattta
    15061 gatggagtaa tggacaggta tgatgcagac tttagagata gtaaagtaca aagttttgga
    15121 gatttggata aaaaagaaaa agcatccgta atggataggc ttggatactt caaagaaaag
    15181 ataaagaaag gaggcctaca aaatgaaaat attgatagaa agatagagtg taaggaggag
    15241 gttagatagt tggaatatca caaaaatatt agagcaacgg atagagaaat gcagaaactt
    15301 tttgaaaatg aggagtataa ctattccgta agatattttg aaaaaataga agaaaactta
    15361 tttaaaacga taattcgcac accggagaat atagagtttc caaaatccaa aaccttgtct
    15421 ataaacacga taaaaaaact cttagaaaca gatgtaaata ttaactctat gtatatcaga
    15481 gatgaattca ctaaaatgaa aaataaggta tacgaattta atcaaaaaaa atatccgggt
    15541 tatgaggata tggatataaa actaacaata tctactatta agggtatcga ggatttcgat
    15601 acccttaatg atttttatga tagtttgaaa aggaagggat atttagaagc gataaaagaa
    15661 agtattaaaa atattattga taaagaatta gaagaaaaca tacaagtaaa agtacaggag
    15721 gtaaaaaata tgaaattaga aaaaggcgat attgtaaaaa cagcattaag tgaaaacaca
    15781 acagttttgg atgtgaaaga taatcaggcg gtactgtttt caggtactca gtttgtactt
    15841 gcaacaggga ttaaagaaaa caaggaaagc ggaaaatttg aatgggataa tgggcgatat
    15901 gcaaatgatt taaaaagcat ttccgatata caaaacaata attttgaaac gatgaaagag
    15961 accttatctt ttttagcaga gtataatcat agcgattttg tcaaaggaat tctgtctctt
    16021 gaaacaggaa tagaaaatga ggatactctt gatgctgctt atgataatta tatgaatgat
    16081 aaaattatgg gtttggttga tgaaaaattt tatcattata tagatgaaaa tgagattgaa
    16141 gcacctgatt tagaaagcga aatacaggat aagaatagtg ttttatccga tgaggaaaat
    16201 gtaaaggagg acaataatac tacgagtgag aagtcaaatg aaaataagga aaaagcaaat
    16261 actgtaaata tcaatggcaa tattgcttca gatatagaca ttaaaaattt gacatcgaaa
    16321 gatggtagag attttactgt tgcaagtttt gcagttgctg aaaatgacaa ggagggaaat
    16381 gtaaaatata ccaactgttt agcctataac gataaggtaa gtagtgtaga aaatttgaaa
    16441 aaaggagatt ttgttcatgt attcggaaaa gaaaaaatca gtcagggaaa ggacggaaag
    16501 gaatatacat ctcttaaagt ttattctgca aagctgttaa aagccaaaga acagagcaaa
    16561 acaaatcaaa atgcaaagga tgtaaagaaa ccgtcagcac ttggcaagtt aaaagagtat
    16621 aaggaaaagg caggcgaaaa atcaaaggaa caggtcagtg tcaaaaaaga taaaaatata
    16681 gagagataaa attataaaaa tagt
//
LOCUS       DARYNN010000045        15947 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.045, whole genome shotgun sequence.
ACCESSION   DARYNN010000045 DARYNN010000000
VERSION     DARYNN010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15947)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15947)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15947
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.045"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            104..313
                     /locus_tag="TVB59_001531"
     CDS             104..313
                     /locus_tag="TVB59_001531"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010408.1"
                     /translation="MTQVRVYLWLSCDDGDNIESNSMTSRKPLAKEDIKKVIVACLSF
                     SEVGYRLKEKGLGIRVSFWLLKSVI"
     gene            458..934
                     /locus_tag="TVB59_001532"
     CDS             458..934
                     /locus_tag="TVB59_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEL1010409.1"
                     /translation="MTQDYISYIRSKVGHDNIILTFAGGILANAEGKVLLQLRADKKT
                     WAIPGGAMELGESSAETCRREFYEETGITVEPLRLLNVYTNFEETYPNGDKVQTVVML
                     YEVIAKADKAITDYQNDETLRLGYFSREEIAELSSISDKHRLMLAEYFAGEFQMGH"
     gene            complement(1097..2299)
                     /locus_tag="TVB59_001533"
     CDS             complement(1097..2299)
                     /locus_tag="TVB59_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEL1010410.1"
                     /translation="MKTDKQQELYAKILDTIYAQRPISRIDISKLTHITPATVGAITK
                     ELLAQGWIHEIGELTDHSVGRKKILLDASANAFYFAGVELSEKHFYLVITDNLGTIYA
                     KHNQQIDPSISSYYKADYISELIQAFLKQHKHYDVQAIGIALPGHYDHSTSSSTHINT
                     NNPIWQQVDLTAIAKSFPIPVVFSNNAHCMIIAKRLYERQAHNHNFIFFHVGRGMHCS
                     YMYKGVIYSRHNAVVGEIGHTIVNPTGELCECGKKGCLQTYASNAWLLKKAKLLHQYA
                     PNSHLRSLVDKACELKLDHLLIAYELGDVGVTTLIHTAIDYLVLSLSNLSLLIDTEQI
                     YLHGRFISHPLISSKILQALQNDIKLLSNQKKPEIIVMPFSVYNAAVGATGLCIDELY
                     LNYKNKYD"
     gene            2479..3378
                     /locus_tag="TVB59_001534"
     CDS             2479..3378
                     /locus_tag="TVB59_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HEL1010411.1"
                     /translation="MKTRLLSASSSEMLQLTSLELKQAIKASEGRTIVSENVAPRPSW
                     TGDDLTNAEVAAAFSADLILLNCVDVFDVQISGLPATDQPILELRRLVGRPIGVNLEP
                     IDLDVDMTEKRLELVEGRQATAKTFQEIEALGFDFVCLTGNPGTGVSNNQIERAIQQA
                     KHYFSGLIIAGKMHAAGSNEAVIDLETVRRFIEAGADVILVPAVGTVPGFTEGDLRAI
                     VEEVHAHDALVMSAIGTSQEGSDTTIVRDIAIRNKICGVDIHHIGDAGYSGIAPVENI
                     FALSDAIRGKRHTIVRMSRSIRR"
     gene            3402..3719
                     /locus_tag="TVB59_001535"
     CDS             3402..3719
                     /locus_tag="TVB59_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1010412.1"
                     /translation="MSKKQIMLACAAGMSTSLLVTKMEKAADNRGLEADIFALPLTEA
                     EDYALSHPVDVVLLGPQVAYQLSAFQESLAEKDIPVAVVPMVDYGMMNGDKVIALAES
                     LMK"
     gene            3729..4061
                     /locus_tag="TVB59_001536"
     CDS             3729..4061
                     /locus_tag="TVB59_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEL1010413.1"
                     /translation="MEDKQLETIMGLIMHGGSAKSLAMEAIAFAKKGELNQAQESLKQ
                     ADKALVQAHHAQTDMLTQEARGNATPVSLLLVHGQDHLMTSITFVDLARELVSIYERL
                     TSQGGNND"
     gene            4054..5370
                     /locus_tag="TVB59_001537"
     CDS             4054..5370
                     /locus_tag="TVB59_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL1010414.1"
                     /translation="MTKFEDFIQQKLVPVAGRLGSNRFLIAIRDGITYAMPLILIGSF
                     LMVIASLPIPGWEAWLGEIGVSTYLWKGVDSSFNLIALVAAFGISYSLAKQYKADGIS
                     AGIINISAFLTVTPFTVSFVNESGKALGEVAGIAPSYLSSGGLFVAIVLGLVNGYAYQ
                     WFMKKDIRIKMPEGVPPAVSKSFSAIIPGAVIIVFWLAVYAFLDHFSLPNVHDIVKSV
                     LGVPFGLLGSTLFGNFIVVLLNGFLWFCGVHGGNVLNNPIMKPIWLSNLTENMAAHKA
                     GQELPHVFTSVFMDNFVFIGGAGATIGLVLALAWLARRRKASQQAKVLSPLTLIPGFF
                     NINEPTMFGLPVVLNLLTVIPFVLAPVMNLFVAYFAFASGIVPGTYADPGWTMPPVIS
                     GFLATGSWQASVLQLVLIILDILLYLPFIINVERRWQASEQTKNEG"
     gene            5435..6782
                     /locus_tag="TVB59_001538"
                     /pseudo
     CDS             5435..6782
                     /locus_tag="TVB59_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677596.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
     gene            6955..11595
                     /locus_tag="TVB59_001539"
     CDS             6955..11595
                     /locus_tag="TVB59_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 16 glycosylhydrolase"
                     /protein_id="HEL1010415.1"
                     /translation="MLFNPIGKEQIRKYAIKKLSVGVASVCVGIGLAAGLPVAVYADD
                     VSEVSLQQPTKAAVTEISHEQEPQATDTDSEALVVSEETTVDEAVVANAVTSNAADQT
                     ADEEKSNAPIELNKVANGGFDNDYVSNKNQWQYREGGHSVLTTENGNSYAEVTSGTLD
                     EHILQKVSTTVGKTYTLEADVKVEADTPHNGLYLTAKESNHNLQGPVIKEVSLTDTDG
                     TWSHIKLSFTATTSETFVGLVKWLEASSPEALAASASIDNVSVVEENDYELIWQDEFS
                     GDRLNQENWGYELGSIRGNEQQHYTDSTENVYLDNGNLVLNVTERYGEDRYANPRGGT
                     SARQVIYDSGSVRTVGKQEFLYGRIEARAKLPKGKGAFPAFWTLGADFTLDGDIASTQ
                     GYGWPSTGELDIMELIGAPNGEHEGELAEGDQSNKTVYGTPHFYYIKGDADKDGSYSP
                     TALGGNLTLSDDFYDDYHIFGINWYPDKIEWYVDGIVYNTMYLTGDDRLEAAAAAFNK
                     PQYLQFNLATGGNWSKNAGYYLASDETAFVIDYVRYYQDAEQKAASEAYYASQPVLKG
                     VKDLTMLEGTSPDLAQAVTTDQEGYVVDFSVENEYLFTNKGGNTNAALQAAGRDDLSA
                     LSELAPGIYNIYYSAVPYNADLGSTVTPTAKIAREVAILTVLPKEGLIGKKGEPLSTV
                     ALPANWQWVTPEEILGSAEHYQIKYTTEGGRAVYTSIEASYISDQPISDQASILVDLG
                     NAILDATAEKAAVTDDEALGKLDDVMNLTQGTVTIRYRLDTADTTVRSSSPLALLSIS
                     NQASANEYASFFIEPKNNKIGLEFKGAEVPIVKVGSGFNLLTNSDWQTISYVFTGSRL
                     KIYLNGDLYGEADFAGFMKQLPWKASADTLTIGGLKRTYDGESVLHWGLKGLVDQVLI
                     DTDVYDLTDIAKAHQPTLRPVTGEKTNVWDKYDEGVFEYRIPSVVKTPSGTLIAAADA
                     RKKHYNDWGDVATVVRISHDDGKTWSNNITVLDMPTQPYFTTQYSLADWNTNMTQSAF
                     SIDSTLLTDASGKLYLLVDVFPESQGAVASKAGSGYELINGQYYLNLYDFDNNKYTVR
                     EGGIVYDQSGHQTDMYVDEGNFETAFSTRGNLYQTEAGEDILLGNIYLRSGRTKQGIT
                     REGSQTAPLFTYMTSFLWLLTSEDEGQTWSTPLDITPQIKEDWMGFLGTGAAAGIEID
                     AVNAEGEQVKRLVFPIYYTNQQNATSASLGRQSSANIFSDDGGQTWQRGESPNDGRIY
                     GHNQQTTSKDFDTSVTELTENQIIQLNNGHLLQFMRNTGKTIVIARSTDYGMTWDDNP
                     TITDLPEPYVNLSAIHMMVDGKEYVVLSNPLGEPSGEQLTIRNQRMKGILRVGEVLED
                     DSIHWVASTIFEPKRFAYSSLVQLDDERVGLLYEYSGQITYSTFNIKQMISDQFREDK
                     AEIEEVTITSAAPKQNGKVSITIQMTFNQPMFILGDRQLAVTVNGVDKLASYVSGDGT
                     DTAIFELSLESMPEGPITVLPQFDHTIVETKYGIRLTDDKAYTVSYPAAVTA"
     gene            11756..13555
                     /locus_tag="TVB59_001540"
     CDS             11756..13555
                     /locus_tag="TVB59_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEL1010416.1"
                     /translation="MERFQISDQFYLDGRSLQILSGAIHYFRIHPDDWYHSLYNLKAL
                     GFNTVETYVPWNLHEAREESYDFSGQLDVEAFLTLAQQLGLYAIVRPSPYICAEWEFG
                     GLPAWLLTKNCHIRSSDPVYLAYVRRYYEELLPRLARHEWQQGGNILMFQLENEYGSY
                     GEDKAYLTAVKGFMEEHLSAPLFTADGPWRATLRAGSLIEDDVFVTGNFGSRAQENFA
                     DMQAFFSEHGKHWPLMCMEFWDGWFNRWHEPIIKRDPEERADAVMEVLAQGSINLYMF
                     HGGTNFGFMNGCSARKQLDLPQVTSYDYDAILDEAGNPTAKFYAIQKRLTAELSEIEV
                     TPPLIKPLMSLPLIGLKDKVSLFSTLEHISSCQTACYPSNIEALGQSTGYILYRTHLL
                     KDKREDERLRLIDSRDRAQVFLDGQKVATQYQETIGDDIIINQQHALSQVDVLIENMG
                     RVNYGHKLTAPSQSKGLGRGMMADLHFVTNWEMYCLPLDDLSQLCFDGDFYEGQPGFY
                     HYQFECHEPEASYIDMTGFGKGCVFINNHPIGRFWEVGPLLTLYIPKGYFNKGLNDIV
                     IFETEGVYQDSIRLVDRPISIDYPQADDRTDQT"
     gene            13970..14791
                     /gene="mutM"
                     /locus_tag="TVB59_001541"
     CDS             13970..14791
                     /gene="mutM"
                     /locus_tag="TVB59_001541"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEL1010417.1"
                     /translation="MPELPEVETVRRGLERLVVGKQIAAVTVRVPKMVKTDLEHFVMT
                     IPGQQVQGVDRRGKYLLFDFGQLVMISHLRMEGKYLLFPDTVPEHKHFHVFLTMTDGS
                     TLVYQDVRKFGTFDLLPKAELAAFFQKRQLGPEPTKQTFQLKTFEAALLASKKTIKPH
                     LLDQTLVAGLGNIYVDEVLWAARVHPERRSASLKKAEIKRIHDETIRILQLGIEKGGS
                     TVRTYQNTLGMNGSMQHYLMVYGQTGKPCQRCGTSIVKLKVGGRGTHVCPRCQKQ"
     gene            14788..15381
                     /locus_tag="TVB59_001542"
     CDS             14788..15381
                     /locus_tag="TVB59_001542"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEL1010418.1"
                     /translation="MTKVIGITGGIASGKSTAVALIRQAGYQVIDADQVVHELQKKGG
                     KLYQVLLETFGQDILLPSGQLDRPKLAELLFAHSENMAKSSQQQNAIIREALAKQKEE
                     LSQTEAIFFMDLPLLVELGYQDWFDAIWLLYVDEETQLKRLMKRNQLTELAARQRIAS
                     QLPMSQKRAYADLVIDNTGDFQALETQISKALHDLEA"
     gene            complement(15544..15900)
                     /locus_tag="TVB59_001543"
                     /pseudo
     CDS             complement(15544..15900)
                     /locus_tag="TVB59_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677601.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
BASE COUNT         4271 a         2921 c         3992 g         4763 t
ORIGIN      
        1 ttataaaggg tattttattt aaagattttg aaggaaaaaa acacctatag gtacaatcaa
       61 tcaaaaaaac agtaggtacc tactactgat tgaggagaag gcaatgacac aagtacgtgt
      121 ttatttgtgg ttatcatgtg atgatgggga taatattgaa agtaattcaa tgaccagtcg
      181 caaaccattg gccaaagaag acattaaaaa agttatcgta gcttgtctga gtttttctga
      241 ggttggttat agattgaaag aaaagggact tggcattcga gtctctttct ggcttttaaa
      301 aagtgtgata taatcaggtt gaaaaattag ggctatatgc tttgccagcc tatcaaggac
      361 aagagacaaa gcctgcattg cttattggtt ggcaaaaaag cagcaattgc gccagctgac
      421 tggctttaat cttatgatgg caatgaaggg agttacgatg acacaggact atatttccta
      481 tattcgctca aaggtggggc atgataacat tattctgact tttgctggtg gtattttggc
      541 caatgccgaa ggtaaggtgc ttttgcagct acgtgcagat aagaaaacct gggcaattcc
      601 gggaggtgcc atggagctgg gtgagtcttc tgctgaaacc tgcaggcgtg aattttatga
      661 ggagacgggg attacagtag agcctttacg gttgttgaat gtttatacca attttgaaga
      721 gacctatcca aatggtgata aggttcagac cgttgtgatg ctttatgagg ttatagccaa
      781 ggcagataag gctatcactg attatcaaaa tgatgaaacc ttaaggctcg gttatttttc
      841 tagagaagag attgcagagc tgtcttcaat ctcagacaag catagactga tgctggcaga
      901 gtattttgct ggtgagtttc aaatggggca ttaggataga acagagagaa ccaagtgcct
      961 ctcttttttt atggttatca tttgtctcgc acctgcggag cgagatggac tgaaagtcgc
     1021 ataatgcaaa agcccacttg agaaatagct tctcaaatgg gctttaaagc tttagctgat
     1081 attggtgtgg gggttatcaa tcatatttgt ttttataatt gaggtaaagc tcatctatac
     1141 ataagcctgt agctcccaca gcggcattat agacagaaaa aggcatgaca atgatttctg
     1201 gctttttttg attgctaaga agcttaatgt cattttgcag ggcttgcaga attttggagg
     1261 atataagagg atggctgata aatctgccat ggagatagat ttgctcggta tcaatcagta
     1321 aggagaggtt agacagggat aaaacaaggt aatcaatagc tgtgtgaatg agcgtggtca
     1381 ccccgacatc accaagctca taggcaatca agagatggtc tagcttgagc tcacaggcct
     1441 tatcgacaag gcttcttaga tgagaattgg gggcatactg atgtagcagt tttgcttttt
     1501 tgagcaacca ggcattgctg gcataggtct gtaaacagcc ttttttgcca cattcacaaa
     1561 gctctccagt ggggttgaca atggtatgtc cgatttcccc aacaacagca ttgtgacggc
     1621 tataaatgac ccccttatac atataggagc agtgcatgcc tcgtccgaca tgaaagaaaa
     1681 taaaattgtg attatgtgcc tgacgctcgt ataagcgctt ggcaataatc atacagtgag
     1741 cattgttgct aaagaccact ggaataggga aggacttcgc aattgcggtt aaatcgacct
     1801 gctgccagat gggattgttg gtgttaatat gcgttgagct ggaggtggaa tgatcgtaat
     1861 gcccaggcag tgctattcct atggcttgta catcatagtg cttgtgctgc ttgaggaagg
     1921 cttgaatcag ctcagagata tagtctgctt tgtagtagga ggaaatgctt gggtcgatct
     1981 gttggttgtg cttggcatag atggtgccca ggttatctgt aatgaccaaa tagaaatgct
     2041 tttcggacaa ttcgacacca gcaaaataaa aggcgttagc cgaagcatca agtaatattt
     2101 ttttgcggcc aacggagtgg tccgtcagct ctccgatttc gtgtatccac ccctgtgcta
     2161 gcagctcttt agtgatagcc cctactgtag caggtgtgat gtgcgttagc tttgaaatat
     2221 caatgcgtga aataggccgt tgggcataaa tggtatctaa aatttttgcg taaagctctt
     2281 gttgtttatc cgtcttcata gtaacctcta ttatcgtacc tctatcatac caaaaaagaa
     2341 ttaaaaatcc tgcctgaaaa cgttgacaaa tattggtaaa tagaatatac tttatttgtt
     2401 tataaaaagt aaacaaataa gagttaaatc ttatttatct tttgttaatg tttttaaaat
     2461 aaaaataaag gagaagcgat gaaaacacga ttattgagtg ctagtagctc agaaatgcta
     2521 cagttaacat cgttagagct aaagcaagcc attaaggcaa gcgagggacg taccattgtc
     2581 tcagaaaatg tagcgccaag accctcttgg actggagatg accttacgaa cgctgaggtt
     2641 gccgcagcct ttagtgctga tttgattttg ctgaattgtg tagatgtctt tgatgttcaa
     2701 atatctggtc tacctgctac tgatcagcct attttagagc tgcgtcgtct ggtggggcgt
     2761 ccaattggtg ttaatttaga accaattgat ttggacgttg acatgactga aaagcgcttg
     2821 gagctagtag aagggcgaca ggcgacagct aagacctttc aagagattga agccttgggc
     2881 tttgactttg tttgcttgac aggaaatcca ggtactggtg ttagcaataa tcagattgaa
     2941 agagctattc aacaggccaa gcactatttt tcaggcttga ttattgctgg aaagatgcat
     3001 gctgctggct ctaatgaagc ggtgattgac ttagaaactg ttcggcggtt tatcgaggct
     3061 ggggctgatg tgattttagt tcctgctgtt gggacagttc ctggctttac agagggtgac
     3121 cttagagcta ttgttgagga ggtgcatgct cacgatgctc tagttatgtc agctattgga
     3181 acgagtcagg aagggtcaga tactacgatc gttcgagaca ttgctattcg caataaaatc
     3241 tgtggtgtcg atattcatca tatcggagat gctggctata gcgggattgc gccagtggaa
     3301 aatatctttg ctcttagtga cgctatccga ggaaaaagac ataccattgt gagaatgtcg
     3361 cgctctattc gacgttagga tttgggataa aggagaagat catgagtaaa aaacaaatta
     3421 tgttggcctg tgcagcgggt atgagtacca gtctattagt gacaaagatg gaaaaggctg
     3481 ctgacaatcg ggggcttgag gcagatattt ttgcattgcc attgactgag gcagaggatt
     3541 acgctctaag ccatcctgtt gatgtggtgt tattagggcc acaggttgct tatcaattgt
     3601 cagcatttca agaaagcttg gcagaaaagg acattccagt ggcggttgtg ccaatggttg
     3661 attacggtat gatgaatggt gataaggtta ttgccttagc tgaaagtttg atgaaatagg
     3721 tggtggtcat ggaagataag cagctagaga cgattatggg cctgatcatg catggtggta
     3781 gtgccaagtc gcttgcgatg gaggcgattg cttttgctaa aaagggagag ctcaatcaag
     3841 ctcaggaaag tctaaagcag gccgataagg cattggtgca ggcccatcat gcacaaacag
     3901 atatgctaac tcaagaggca cggggaaatg ctacaccagt aagcctacta ttagttcatg
     3961 gtcaggatca tttgatgact agtattacct ttgttgattt ggcaagggag ctagtatcta
     4021 tttatgaaag gttaacgtca caaggaggta acaatgacta aatttgaaga ttttatccag
     4081 caaaagcttg ttccagttgc tggtcgccta ggaagcaatc gctttcttat tgctattcgt
     4141 gatgggatca cctacgctat gcccttgatt ttgattgggt cctttttaat ggtgattgct
     4201 agcctgccga ttcctggttg ggaagcttgg cttggtgaga ttggtgtctc tacctatctg
     4261 tggaagggag tagattcgag ctttaatctg attgccttgg ttgcggcctt tgggatttct
     4321 tatagcttgg ctaagcagta taaggcagac gggatttctg ctgggattat taatatctct
     4381 gcctttttaa cagtgacccc atttactgtt tcatttgtca atgaatctgg taaagccttg
     4441 ggtgaggtag cgggtattgc gccttcttac ctttcatcag gcggcttgtt tgttgccatt
     4501 gttttgggat tggtaaatgg ctatgcttat caatggttta tgaaaaagga tattcggatt
     4561 aagatgcctg agggtgtgcc gcctgcagta tcaaaaagct ttagcgccat tattcctgga
     4621 gcggtgatta ttgtgttttg gcttgctgtt tatgctttct tggatcattt tagcctgcca
     4681 aatgtccatg acattgttaa gtccgtacta ggagttccat ttggcttgct gggaagtacc
     4741 ttatttggta attttatcgt tgttcttctt aatggctttt tatggttctg tggtgtgcat
     4801 ggtggaaatg tcctaaacaa tcctattatg aagccgatct ggttatctaa cttgactgaa
     4861 aatatggcag ctcataaggc tggtcaggaa ttgccgcatg tctttacgtc tgtctttatg
     4921 gataactttg tttttatcgg cggagctggt gcaaccattg gcttggtgtt ggctttagcc
     4981 tggttagcac gtcgtcgcaa ggctagtcag caggcaaagg tcttgtcacc attgaccttg
     5041 attccagggt ttttcaacat taacgagccg accatgtttg gcttaccggt tgttttaaat
     5101 ctattgacag ttattccttt tgtactagca cctgttatga atttgtttgt cgcttatttt
     5161 gcctttgctt ctggcattgt acctggcacc tatgctgatc cggggtggac catgccgcct
     5221 gttatttcag gatttttggc aacgggcagc tggcaagcct cagtcctaca gcttgtttta
     5281 attattctag atattcttct ttacttgccg tttattatta atgtggaaag aagatggcag
     5341 gcgagcgagc aaactaaaaa tgaaggctaa gctgttagag agagccttta ctgctctatc
     5401 ttagctgttt tatgattgtt ttaaggagct atgaatgaat aactatatga actttctttc
     5461 gcaaaagctg ctgccaattg ctacgaagat tggtaatcaa cgatttttag tggccttgcg
     5521 agattctttt attgcaacga tgccggttgt gatgacaggc tctattgccc tgttgatcaa
     5581 tgccttttta gtggatattc cagaccaatt tggcttgcaa ggcattacag aggccttcca
     5641 atggtgggta accatcaaca accttgtctt taagggaagc atttcgattg tgtccttgct
     5701 atttgtgtat tgcttagggg ttaatgtcgc taaactttat aagacagata cgctctcatc
     5761 aggtttggtt tctttagctg cctttgtgat tgcgattggg gattctgtta cctctagcat
     5821 tgacgcgtca ggtctcaagg gtgttgatct tgtgacggct tttaaggaca gtggtgttac
     5881 tgtcagcggc agctcactta atgtgaccat ctcaggccta ttgcctggtg cgcaaattaa
     5941 ctccaatggt tattttacag caattatgat tggcttttta gcctctatta ttttttgtaa
     6001 attaatgtta aaaaattgga caattaaatt accagatagt gtgccacctg ctgtagccaa
     6061 gcccttctta tctatcatac caggcttttg cgccttgtat agcgtagcta ttttaacatt
     6121 tgtctttgaa aagctaacgg gttctttgat gattgattgg atctataagg tcttgcaaat
     6181 cccacttttg ggcttatcac aaagctttat tgctgttgtt ttggtagctg ttttgaccca
     6241 atttttctgg ttctttggga ttcatggcgg caatgttatg gcgccaaata tggagggagt
     6301 atttggtgtt gccctcttgg ctaatttgga ggcttatcaa aagcatgagg cgattcctta
     6361 tctttggacg agtgttcttt gtatggtatg caaccttagg gctcttgatt gctattttct
     6421 ggaagtctaa aaatgaacac tatcgtgagg tggctaagct aggtgttgct cctgtattgt
     6481 ttaatatagg agagccagtg atgtatggtt taccaactgt tttaaatcct ttgttgttta
     6541 ttccgtttat tgtttgtcct gctgttatgt caagtgttgc ttatatcgca actagtctgg
     6601 gcttggttgc acccgttacg caaaatgtga cctgggtaat gccgcctgtc ttgtatggct
     6661 tcttttcaac tggttttgat tggcgtgcta ttgtgctatc gcttgtcaat ttggccttgg
     6721 caaacctgat ttaccttcca tttgttaaga tggctgataa tgagcttgaa aaggcaggtt
     6781 agtcactttg tgagaggata tatcggtttc atctggtata tcttctttta agcgctgaat
     6841 tgaaagcgtt tttataacaa ggtcgttagc ctgaccagca ctggattagg ctaaatgggc
     6901 ctttgaaaag ctattgtgtt taaaaatgat gtatatataa gtgaggaaat aaacatgtta
     6961 tttaatccta tcggaaaaga gcaaattaga aaatatgcca tcaaaaagct tagtgtcggt
     7021 gttgcttcag tgtgtgtggg tattggtctt gctgctggtc tgccagtggc tgtttatgct
     7081 gatgacgttt cagaggtaag cctgcagcag cctacgaaag cagcagtaac agagataagc
     7141 catgagcagg agcctcaagc tacagataca gatagcgagg ccttagtagt ctcagaggag
     7201 acgacagtag atgaggcagt agtagctaat gctgtgacca gcaatgctgc tgatcagaca
     7261 gcagacgaag agaagtctaa cgctccgatt gagctcaata aggtggctaa tggtggtttt
     7321 gacaatgatt atgtgtccaa taagaatcag tggcaatata gagagggagg tcattcagtc
     7381 ctcacaacag agaatggtaa tagctatgct gaggtaacaa gcggcacttt agatgagcat
     7441 atccttcaaa aggtgtctac aacggttggg aaaacctata cgctagaggc tgatgtgaag
     7501 gttgaagctg acacacctca taatggctta taccttaccg ctaaagagtc caatcacaat
     7561 cttcagggcc ctgttatcaa agaggtcagc ctcacagata cagacggtac ttggtcacat
     7621 atcaagctct cctttacagc aacgacttca gaaacctttg ttggcttagt caaatggttg
     7681 gaagcctctt ctccggaagc cttggctgcc tctgctagta ttgataacgt gagtgtcgta
     7741 gaggaaaatg attatgaatt gatttggcag gatgagtttt caggagatcg gttaaaccaa
     7801 gagaactggg gatatgaatt gggaagtatt cgcgggaatg agcagcagca ctacacagac
     7861 agcacagaga atgtctatct tgataatggc aatcttgttt taaacgtcac agagcgttat
     7921 ggggaggacc gttatgccaa tcctagagga ggaacaagcg cacgtcaggt catttatgat
     7981 tcaggaagcg tacgaacggt tggcaagcaa gaatttttat atggtcgtat cgaagctagg
     8041 gccaagcttc ccaagggtaa gggagccttt ccagcctttt ggacattggg ggctgatttt
     8101 accttagatg gtgatattgc gtcaactcaa ggctatggct ggccaagcac aggtgagctt
     8161 gacattatgg agctaatcgg tgctcctaac ggagagcatg agggtgagct tgccgaaggt
     8221 gatcaaagca acaaaacagt ttacgggacc cctcattttt actatatcaa gggtgatgca
     8281 gacaaagatg gaagctatag cccaacagca ttgggtggca atctgacatt aagtgatgac
     8341 ttttatgatg actaccatat ctttggtatt aattggtatc cggataagat tgaatggtat
     8401 gttgatggga ttgtttataa taccatgtat ttaaccggtg atgatcgctt agaggctgcc
     8461 gcagctgcct ttaataagcc tcaatacctt cagtttaacc ttgctactgg aggcaattgg
     8521 agtaaaaatg caggctacta tctagcttca gatgagacgg cctttgtgat tgattatgtg
     8581 cgttattacc aagatgctga gcaaaaagca gcctcagaag cttattatgc ctcacagcca
     8641 gttctcaagg gggtcaagga tttgaccatg ctagagggaa ccagtcctga tttagctcaa
     8701 gctgtaacca ctgatcagga aggctatgtg gttgattttt cagttgaaaa tgaatacttg
     8761 tttactaaca agggtggaaa taccaatgct gctttacagg ctgctggtcg agatgatttg
     8821 tcagccttgt ctgagctagc tcctggtatt tataacattt actatagtgc tgttccttac
     8881 aatgctgatt taggctcaac agtaacacca actgctaaga ttgcaagaga agtagctatt
     8941 ttaactgtat tacctaaaga aggtctgatt ggtaagaagg gagaaccctt atctacagta
     9001 gccctgccag ccaattggca atgggttacg ccagaggaga tcttgggaag tgcagagcat
     9061 tatcagatca aatacaccac agaaggcgga cgagctgttt atacaagcat agaagcaagc
     9121 tatatctcag atcagccaat ctcagatcaa gcatccattt tagttgattt aggcaatgct
     9181 attttggacg caacagcaga aaaagcagcc gtaacagatg acgaggctct tggtaagcta
     9241 gacgatgtga tgaacctaac ccaaggaact gtaacaatca gataccgtct agatactgct
     9301 gatacaacag tgagaagctc atcgcccttg gccttgttat cgatctcaaa tcaagcatca
     9361 gctaatgaat acgcctcttt ctttatcgag cctaaaaaca ataaaatagg tcttgaattt
     9421 aaaggagctg aggttccgat tgtaaaagtt ggctcaggct ttaatttatt aacgaactcg
     9481 gactggcaga cgatcagcta tgtctttaca gggtctaggc taaagattta cttgaatggt
     9541 gacttatatg gggaagctga ctttgctggg tttatgaagc aattaccttg gaaggcttct
     9601 gctgatacgc taacaattgg aggcttgaaa cgcacctatg atggtgagtc ggtccttcac
     9661 tgggggttaa agggactggt tgatcaggtg ctgattgata cagatgtgta tgatctgaca
     9721 gatattgcca aggctcatca gccaaccctt cgaccagtta ctggtgaaaa gacgaatgtt
     9781 tgggacaaat atgatgaagg ggtctttgaa tatcggattc cctctgttgt caaaacgcca
     9841 tcaggaacct tgatagccgc agcagatgca agaaagaagc actacaatga ctggggagat
     9901 gttgcaactg ttgtcaggat aagccatgat gatggcaaaa cctggagtaa taacattacg
     9961 gtcttagata tgccaactca gccttatttt acaacacaat atagcttggc tgattggaat
    10021 accaacatga ctcaatctgc tttttcaata gactccacct tgctaacaga cgcttctggc
    10081 aagctttatt tgctggtaga tgtctttcct gagtcacagg gtgctgttgc ttctaaagca
    10141 ggctcaggat atgaattgat taacggtcag tattatttaa atctttatga ttttgacaat
    10201 aataaataca ctgtgcgtga aggtggtatc gtctatgacc agagtggcca tcagacagat
    10261 atgtatgttg atgagggcaa ttttgagaca gcctttagca cacgcggcaa cctctatcaa
    10321 acagaggcag gagaggatat tctactaggg aatatttatc tgagaagtgg tcgcactaag
    10381 caaggcatca ctagagaagg ctcacaaaca gctcctctat ttacttacat gaccagcttt
    10441 ttatggctgc taaccagtga agacgaaggg caaacctggt ccacacctct tgatattacc
    10501 ccacaaataa aagaagactg gatgggattt ttaggtacgg gtgccgcagc tggcattgaa
    10561 atagacgcag tcaatgcaga gggtgagcag gtgaaacggt tagttttccc gatttactat
    10621 accaatcaac aaaatgcgac atcagctagt ctaggtcgtc aaagcagtgc taatattttt
    10681 agtgatgatg gcggtcaaac atggcaacga ggtgaatcac caaatgatgg cagaatttat
    10741 ggtcataacc aacaaacaac ctctaaggat tttgatacat cagtcacaga attgacagaa
    10801 aatcaaatca ttcagctaaa caatggtcac ttattacagt ttatgcgcaa taccggaaag
    10861 acaatcgtta ttgccagaag cacagactat ggtatgactt gggacgataa tcctacaatc
    10921 acagacctcc cagagcctta tgtcaatttg tcagctattc atatgatggt tgatggcaaa
    10981 gaatatgttg ttttatccaa tcctttagga gagccctcag gtgagcaact gacgattaga
    11041 aatcagcgca tgaaagggat tctgcgtgtc ggtgaggtct tagaggacga tagcattcat
    11101 tgggtcgctt caaccatttt tgagccaaag cgttttgctt actctagctt ggttcaacta
    11161 gacgacgaga gggttggttt gttatacgaa tatagtggtc agatcaccta ttcaaccttt
    11221 aatatcaagc agatgatctc agaccagttt cgtgaggata aggctgaaat tgaagaagta
    11281 acaataacgt cagcagctcc aaagcaaaat ggcaaagtaa gcataaccat tcagatgacc
    11341 tttaatcaac cgatgtttat tcttggtgat cgtcagttag cagttactgt aaatggcgta
    11401 gataagcttg ccagctatgt ttcaggagat ggcacagaca cagcgatatt tgaattgtct
    11461 ctggagagta tgcctgaagg accgataact gttttaccgc agtttgacca tactattgtt
    11521 gaaaccaaat atgggattag attgacagat gacaaggcat acactgtctc ttatcctgct
    11581 gctgtgacag catagcatga ggagtcagac tgtagatagt gtttacaatt gttaccataa
    11641 gataagttag cctgtctgct gaatggcctg ttcgctgttg ctagaatggg ccattccaag
    11701 ccgctcagca atgaggccta gtaggctaat agcaataata agtgaggaat taagcttgga
    11761 acgttttcag atttcagatc agttttattt agatggtaga tcgctgcaaa tcctgtcagg
    11821 ggctatccat tattttagaa ttcacccaga tgattggtat cattcgcttt ataatttaaa
    11881 ggcactggga tttaatacgg ttgagaccta tgtcccttgg aatttacatg aggctaggga
    11941 ggaaagctat gatttctctg gccaattaga tgtggaagcc tttttgacgc tggcgcagca
    12001 attggggctc tatgctattg tcagacctag tccttatatt tgtgcagaat gggaatttgg
    12061 tggcctacct gcttggctgc tgacaaagaa ttgtcatatc aggtcgtctg atcctgtcta
    12121 tttagcctat gtgaggcgct attatgagga gctgctgccg agactagcaa ggcatgaatg
    12181 gcagcagggc ggcaatattt tgatgtttca gcttgaaaat gaatatggct cctatggaga
    12241 ggataaggcc tatttaacag ctgttaaggg ctttatggag gagcacctca gtgcgccctt
    12301 gtttacagca gatggtcctt ggcgagccac tcttagagct ggtagtctga ttgaagatga
    12361 tgtctttgtg actggcaact ttggctcaag ggcacaggag aattttgctg acatgcaggc
    12421 cttcttttct gagcatggca agcattggcc tttaatgtgt atggaatttt gggacggctg
    12481 gttcaatcgt tggcatgagc ccatcatcaa acgcgaccct gaagagcgag ctgacgcagt
    12541 gatggaggtt ttggcgcagg gcagtattaa cctgtatatg tttcatgggg gaacaaactt
    12601 tgggtttatg aatggctgct ctgccagaaa gcaattggac cttccgcagg tgacctccta
    12661 tgattatgac gctatcctag atgaggctgg caatccgaca gctaagtttt acgcgattca
    12721 aaagcgtctg accgcggagc tttcagagat agaggttact cctcccttga ttaagccctt
    12781 gatgtcactg cctctgattg gtctgaagga caaggttagt ctgtttagca cgctggagca
    12841 catcagcagc tgtcagactg cttgctatcc tagtaacata gaggctttag ggcaatcaac
    12901 gggctatatc ctgtatcgga cacatctttt gaaggataag cgtgaggacg agcgtttacg
    12961 cttgattgat agtagagata gagcacaggt ctttttagat ggtcaaaagg ttgcaacaca
    13021 gtatcaggag acgattggtg atgatatcat cattaaccag cagcatgcct tgagtcaggt
    13081 cgatgtttta attgaaaata tgggccgggt caattatggg cacaagctga cagcacctag
    13141 tcaaagtaag ggtctaggac gtggtatgat ggctgacttg cactttgtga ccaattggga
    13201 gatgtattgt ctgccgcttg atgatttgtc tcagctttgt tttgatggcg atttttacga
    13261 ggggcagccc ggcttttatc attatcaatt tgaatgtcat gagcctgagg caagctatat
    13321 tgatatgact ggctttggga agggttgtgt ctttatcaac aatcacccta ttggtcgttt
    13381 ttgggaagtg ggtcccttat taacccttta tattccaaag ggctatttca acaagggatt
    13441 aaatgacatt gttatttttg aaacagaagg tgtttaccag gatagtatcc gtcttgttga
    13501 taggccaatt agtatagatt atccgcaagc tgatgacagg actgatcaga cctagcattg
    13561 tcagttgagg cttgcagcat tgcttggttt tctatttaca gacactaaag gccacaacgt
    13621 gcccttgggc tggcaaacaa taggctagct caggggcttt gtctttgctt gctggattgg
    13681 cgggcgagat gtgcttttct gatgctatag cggcagtgac tgcaaaggct gttcgtgaga
    13741 gttgctttct ttatggatta tgcgtaaaat aagaatgata acagttctta tcaaaggata
    13801 gtcctttgtg ctcaagctta ttgaggtttt gggtggggct ttctaatagt agcttataga
    13861 aaggaagcgt gtttgtaaca ttgagactga gtaaagagtg ctaaaactgg ctggttctgc
    13921 tggttttggt tatgtggttt ctttgttagc gcgtttggta tctttaatta tgcctgaact
    13981 ccctgaggtt gagacagtgc gacgcgggct tgagcgctta gtcgttggca agcagattgc
    14041 agcagtgaca gttagggtgc ccaagatggt caaaacagac cttgagcatt ttgtgatgac
    14101 gatccctggg cagcaggtgc aaggggtaga tcgtcgcggg aagtacctgc tctttgactt
    14161 tggccagctg gttatgatct cgcatttgcg tatggagggg aaatacctct tgtttcctga
    14221 tacggtacct gagcataagc attttcatgt ctttttgaca atgactgatg gctccacgct
    14281 ggtttaccaa gatgtgagaa agtttggaac ctttgatttg ctaccaaagg ctgagctggc
    14341 tgcttttttc cagaagcgtc agcttggtcc tgagccgacg aagcagacct ttcaattgaa
    14401 gacctttgag gctgctctgc tagcctctaa aaagaccatt aagcctcatc ttttggatca
    14461 gactttagtg gctggtcttg gaaatatcta tgtggacgag gtgctatggg cagctagagt
    14521 acaccctgag cgtcgatctg ctagcctgaa aaaggcagaa atcaaacgga ttcatgatga
    14581 aacgattcgt attttacaat taggtattga aaagggtggc tcgacggtta gaacctatca
    14641 gaatacctta ggaatgaatg gtagtatgca gcattatttg atggtctatg gccaaacagg
    14701 caagccctgt cagcgctgcg ggacctccat tgtaaagctc aaggttggag gaagagggac
    14761 acatgtctgt cctaggtgtc agaagcaatg acaaaggtaa ttggcattac aggaggtatt
    14821 gcctccggaa aatcaacggc tgtcgcactt atcagacaag caggctacca ggtgattgat
    14881 gcggatcagg tggtgcatga gctgcaaaaa aagggcggca agctttatca ggtcctacta
    14941 gagacctttg gacaggatat tttattgcca tcggggcaat tagacagacc taagctagcg
    15001 gagctgctgt ttgctcattc ggaaaatatg gcgaaatctt cccagcagca gaatgctatc
    15061 attagggaag ccttagccaa gcaaaaagag gagctatctc aaacagaggc tattttcttt
    15121 atggatttac cgcttttagt tgagctgggc tatcaggatt ggtttgacgc tatttggctg
    15181 ctctatgttg atgaggagac tcagctcaag cgcctgatga agcgtaatca attgacagag
    15241 ctagctgcta ggcagcggat tgctagccag ctgccgatgt ctcagaaaag agcttatgct
    15301 gatttagtga ttgataatac tggtgatttt caggctttag agacacagat tagtaaggct
    15361 ctgcatgatt tagaggcgta agccttgcca tgctgttgcc ctagtctagt ggttttggag
    15421 cttctatagc gtatgcaaaa agccttatcg tacccattcg tggtgcgata aggcttttgt
    15481 gctgcattag atggaccatg cacgcattat atactagtgc tgtcttgcat tagcttattc
    15541 agcttattgc tttcttttgc gttttgccag gaagcctagt ccaagaagag agagtaagcc
    15601 tgtaccaagt gcagtcatca agctgccagt gtcatttgtt tttggtagtg ctttgccact
    15661 agattggcta gtagcgtttg acggcttggt tggtttttga ggttttgtct ctggcttagg
    15721 ctctggttta ggcattggtt caggcttagg ctctggttta ggtgccggat caggcattgg
    15781 ttcaggctta ggttcaggtt taggctctgg ttcaggctta ggctctggtt taggcattgg
    15841 ttcaggatct ggcttaggct taggatctgg ttctggttca ggcttagggt caagtttagg
    15901 aattagagta gaaccaagca ggttttgata aggtttatgt taataat
//
LOCUS       DARYNN010000046        15778 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.046, whole genome shotgun sequence.
ACCESSION   DARYNN010000046 DARYNN010000000
VERSION     DARYNN010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15778)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15778)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15778
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.046"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(<1..1468)
                     /locus_tag="TVB59_001544"
     CDS             complement(<1..1468)
                     /locus_tag="TVB59_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Eco57I restriction-modification methylase
                     domain-containing protein"
                     /protein_id="HEL1010419.1"
                     /translation="MMKIIDYVIESTNKYIKQMPKEIRKKNGQFFTSKETALFMASLF
                     DLSSFSKEISILDPGAGSGILTAALIQRIIDTDKIEAIKITCYETNDDILELLNANLS
                     WISKNTSLKIEYKVIKDNYITSQTLEYNNMLGVSTKPEKYDVIIGNPPYLKVGKMANE
                     ALSMPDICYGSPNLYFLFMEMASFNLVDNGELVFIVPRSWTSGAYFKKFREKFLNEVV
                     LKHIHLFVSRDKVFDKESVLQETMIIKAKKELNKLKNITITTTNDNFDFGSKTVFEAS
                     YDMVVSGEHKYVFLITDKEEADTIKKVNEWNDTLPTLGLKMKTGLTVDFRNQEALRND
                     AEEKAVPLFYSQHIKDGKVIFPVGKENEYLLTEKKGLLQENTNYLFVKRFTAKEEKRR
                     LQCGIYLAKKFPTYKAISTQNKINFITGLQGLSDCLVYGLYVVLNSTLYDNYYRILNG
                     STQVNATEINSMPIPPLTCIEDMGKELIKLKDMSEENCD"
     gene            complement(1452..1667)
                     /locus_tag="TVB59_001545"
     CDS             complement(1452..1667)
                     /locus_tag="TVB59_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1010420.1"
                     /translation="MSKISYKKLFKKMIDLDMKNSELMEKAEVSRSTFYKMKNSENIT
                     TDVIVRICDSLNCGVNEIMELVDDENN"
     gene            complement(1817..2476)
                     /locus_tag="TVB59_001546"
     CDS             complement(1817..2476)
                     /locus_tag="TVB59_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006627214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1010421.1"
                     /translation="MDYKTMRNQIEDMANDNHKDFVKAIISVEKGINDESALDKLYDA
                     YMDNDSLNLLHEEFDYMIEDLREQGQIKDLPYVQEEKDNLINIVGNIVGKVDVAEREN
                     KNGEAFKVANFSVVSKDDEGNKVYHNCSAYGEKSDIPKDFKQGDFVKLFGQIRTSIDD
                     NGKEHSNVRILSSKLLKAKEQMKGQEEKKESVLGAIKKYQSEDKEKPKEKRDASKEAE
                     R"
     gene            complement(2520..4430)
                     /locus_tag="TVB59_001547"
                     /pseudo
     CDS             complement(2520..4430)
                     /locus_tag="TVB59_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989360.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
     gene            complement(4538..6303)
                     /locus_tag="TVB59_001548"
                     /pseudo
     CDS             complement(4538..6303)
                     /locus_tag="TVB59_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678622.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="reverse transcriptase"
     gene            complement(6813..13643)
                     /locus_tag="TVB59_001549"
                     /pseudo
     CDS             complement(6813..13643)
                     /locus_tag="TVB59_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365295.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            complement(13815..15242)
                     /locus_tag="TVB59_001550"
     CDS             complement(13815..15242)
                     /locus_tag="TVB59_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA binding domain-containing protein"
                     /protein_id="HEL1010422.1"
                     /translation="MTIDEIKKLIQAGEKIDVEFKESKNALTKDVFDTVCSFNNRNGG
                     HILLGANDKREIVGVSEDKVDKVIKEFTTAINNPQKMYPPLYLLPETFEIEGKQVIYI
                     RVPEGYQVCRHNGRIWDRSYEGDINITDHSELVYKLYARKQGSYFVNKVYPNLDIDFL
                     DASVIDKAKKMAVFRNKNHVWENMSNEELLRSANLILTDPETKREGITLAAILLFGKD
                     NSIMSVLPQHKTDAIFRVENKDRYDDRDVVITNLIDSYDRLIEFGQKHLNDLFVLDGI
                     VNVNARDRILREIVSNTLAHRDYSSGFPAKMIIDDERITVENSNLAHGMGALDLQKFE
                     PFPKNPAISKVFREIGLADELGSGMRNTYKYTQLYSGQNPLFEEGDIFRTIIPLKKIA
                     TQKVGGDNVAHDVAQGVAHDVAHDKIALAEFIKEKVRSNDRITRKAIADEAGVSVKTI
                     ERAIKEIDNLKYVGSGNSGHWELNE"
     gene            complement(15261..15440)
                     /locus_tag="TVB59_001551"
     CDS             complement(15261..15440)
                     /locus_tag="TVB59_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="HEL1010423.1"
                     /translation="MKDTFIDTAKVMSKGQVTIPKRIRELLNLENGDYVTFVVNKDRV
                     EIQNSNVFIEENIKK"
     gene            complement(15524..>15778)
                     /locus_tag="TVB59_001552"
     CDS             complement(15524..>15778)
                     /locus_tag="TVB59_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HEL1010424.1"
                     /translation="QFTRAGIIENLIFKGFVERDKKNLIATHKGISLVAIVADNFKSA
                     ETTAKWEMELSDIAQGKSSKEEFLEAIENEIKEAVSTYSK"
BASE COUNT         4237 a         3489 c         2239 g         5813 t
ORIGIN      
        1 catcacaatt ttcttcagac atatccttta atttaatcag ttcctttccc atatcctcaa
       61 tacaagttag tggtggaatt ggcatcgagt taatttcagt agcattaact tgagttgatc
      121 catttaaaat tctgtaataa ttatcataaa gcgtagagtt caatacaaca tacaaaccat
      181 aaaccaaaca atctgataat ccttgtaagc ctgtaataaa atttatctta ttctgtgtgc
      241 taattgcctt atatgttgga aattttttag ctaaataaat tccacattgt aatctacgct
      301 tttcttcctt tgccgtaaat cttttcacaa ataaataatt agtgttctcc tgcaataatc
      361 cttttttctc cgttaataga tactcatttt cttttccaac aggaaaaatc actttaccat
      421 cttttatatg ttgcgaataa aataaaggaa ctgctttttc ctctgcatca tttcttaaag
      481 cctcttgatt tctaaaatca actgtcaaac cagttttcat tttcaagcca agagttggca
      541 aggtatcatt ccattcattt acctttttaa tcgtatcagc ttcttcttta tcagttatca
      601 aaaaaacata tttgtgttct ccggaaacaa ccatatcgta agaagcttca aaaacagtct
      661 tgctgccgaa atcaaaatta tcattcgttg tagttatagt aatgtttttt aacttattta
      721 attctttctt ggctttaata atcatagttt cttgcaaaac agactcttta tcaaagactt
      781 tgtctctgct tacaaataaa tgaatgtgct tcaaaaccac ttcatttaaa aacttctcac
      841 gaaacttttt aaagtacgct ccagaagtcc atgatcttgg aacgataaac accaattcgc
      901 cattatcaac caaattgaaa cttgccatct ccataaaaag aaaatataaa ttcggtgatc
      961 cataacaaat atcaggcatg gataaagctt cattagccat ttttccaacc tttaaataag
     1021 gtggatttcc tataattaca tcgtattttt caggtttagt actcaccccc aacatattgt
     1081 tatattcaag tgtttgactt gttatatagt tatctttaat cactttgtat tcaattttta
     1141 gtgatgtatt cttacttatc cacgataaat ttgcatttaa cagctctaaa atatcatcat
     1201 tggtttcata acaagtaatt tttatggctt caatcttatc agtatcaata attctttgaa
     1261 taagagctgc cgtaagtatt cctgaacccg ctcccggatc gagtatagaa atttcttttg
     1321 aaaatgatga taaatcaaat aatgatgcca tgaaaagagc tgtttcttta cttgtgaaaa
     1381 attgcccatt tttcttgcga atttcttttg gcatctgttt aatatattta tttgtagatt
     1441 caattacata atcaattatt ttcatcatcc accaactcca taatttcatt tacaccacag
     1501 ttcaaactat cacatattct gacaatcaca tcagtagtaa tattctcact gttcttcatt
     1561 ttataaaaag tactccggct aacttctgct ttttccatta gctcagaatt tttcatatct
     1621 aaatctatca tttttttaaa tagcttttta taacttattt tcgacacgat tgtcctccca
     1681 tgcatatgat tttgttttta tcattatatc atatttattc acttttttca ctacaaactt
     1741 ccttttacac aaacacacga catttagata gacaaaaaag agtcggtgca gtcctaagac
     1801 cacaccgacc atatatttat ctctcagctt ctttgcttgc gtctctcttt tcttttggtt
     1861 tttccttatc ttcagactga tatttcttga tagctccaag aacagattct ttcttttctt
     1921 cttgtccttt catttgttcc tttgccttta agagctttga agaaagtatc cttacattgc
     1981 tatgctcctt gccattatca tcaatggaag ttctgatttg tccaaagagc tttacaaaat
     2041 ctccctgctt aaagtctttt ggaatatcac tcttttctcc ataagcggag caattatgat
     2101 aaaccttatt tccctcatca tctttagata caacagagaa atttgccacc ttaaaggctt
     2161 ctccattctt gttttctctt tcagctacat caacctttcc tacaatattt ccaacgatat
     2221 tgataagatt atctttctct tcctgaacat agggcaggtc ttttatttgc ccctgttctc
     2281 gtaaatcttc aatcatgtag tcaaattcct catgcagtaa attcagactg tcattgtcca
     2341 tataagcgtc atagagcttg tccaaagcac tttcatcatt gatacctttc tccacgctta
     2401 taatcgcttt tacaaagtcc ttgtggttat catttgccat atcttctatt tgatttctca
     2461 ttgttttgta atccatgttt tttatctcct ttcatagtaa aagggaggtt accctcccct
     2521 tatcttaaaa attcctgttc ttttgtagtt tgtttttctt ctgttttact ttcttcctga
     2581 taggctctta tctgtcctaa aatagatggc ttatcctctg atttttgtga actttcttct
     2641 ttgctatgaa aattatcctc cacatcatat gttgattcaa aatagtcgct gtccttaaag
     2701 tcattatcgt aacggtcagt aattccgtca ttatcaaggt ctttagaaag cggatcatag
     2761 aagttacctt cgtcatcaat atcaagtccc gttgctgctt tcaaatcttc tgaatccaca
     2821 taaaccagat cttcaaaaga ggatagctca atctcatttt tcatatttct tagagtttca
     2881 ttctctcctt tgttctcata gtcaaagctc tcagttttta tagatatatc atcaatatac
     2941 tgtgtccata tcttatcctc taaattaagc tcatattgaa tgctgtgtct ttcatccggc
     3001 gtgttggtat aggcaattcc tatatgcttt aagtcaggat atagagcatc aaactcatcg
     3061 tagctatgat tttcttcata ttctctgtta cagaaatcaa taattgccct tttaacatct
     3121 tctacaaggg gattatcatt tctcttttct tccacatcac ccatatcaag tagcttattt
     3181 agttcagcca agcgaagcac cttactcttt aattcatcag ctttttcaaa cggctttttt
     3241 aattcctctt tggcattttc aagctgctct ttggtgctta tgagcttttc ttcaagcctc
     3301 tttaatttct caggcatttt ctcaagagcg ttatcaagtc ttgtaatatt accgtcagca
     3361 cttgtgccaa gctctcctga atgctttgca acaccgttta agctgaaatt atgagaatta
     3421 gtaaagaagt tataacttgc ttccaagtcc atatttctgt acttaccgat taccttactt
     3481 tcattgattt taacctttga aatagcttca agcaatcttt ctcctgctaa tttcttatcg
     3541 gtaatctttg ctcctgcgat agtaatagaa gtaaactttt cctctccgtc cgctttaggc
     3601 tctacatcag atatatcttt cttgacagct tctatgagct tttcagttct tgcgatttct
     3661 tcaggatagt ttttcgccac tttatcctct aatctgtaac ggttggactt atagtttgct
     3721 tcaagcattt taagtttcgt aacctcatta tccaaatcca tcttttcttt aatcttcgga
     3781 tcacctgtgg caagggcttt aatttctgca tagttaagtg aactttcatc cacatcttct
     3841 gccactctga caggtgtttt acttgtcata atctgagaaa tgaacttctg cttattctct
     3901 attgtctgcc acaaatacgc atcaaaggtg ttctccgtaa cataacgata gatatttact
     3961 tccttgtttt cattgccctg tcttacaatt ctgcccgcac gctgctctaa atcggcagga
     4021 cgccaaggaa catccaaatc atgaagggca atcagtttgt tttgtacatt cgtgccggct
     4081 cccattttct gagtagaacc aagtaatatc ctcacatctc ctttacgcac ctttgcaaag
     4141 agttcgtcct tttgtttatc ggaattcgct tcgtggataa aggcgatttc ttcttttggt
     4201 attcccattg ctacaagttt ttctctaata tcatcataga tgttaaattc tccatcgcct
     4261 tttggtgtag acatatcaga aaatagtagc tgtgttgact tatcttcttt tgtcttatcc
     4321 catatactaa agacattttt cacacagaca ttgaccttac tgtcaggatt gtcaggtagc
     4381 agaggattaa ttaaacgctg atctaaggca agttttttac catcattagt gtagggtagg
     4441 atactagcga ggtagtcatt gcgacccctt ttccattatc cccccaccga accggacatg
     4501 atactttcgc atcatccggc tctccagtaa tttcatttca taaacgtgta tttattgaac
     4561 cattatgtat tgcatggtga caatcccgac aagtcactag catttttcga cgtcttgctg
     4621 acatgatttc tttccacttt ggaactaatt tcccattgtg tttgttcaag tctgctaatt
     4681 ttctgatatg atgtacctct atgttctcct cacttccaca tagctcacac ttatttgcga
     4741 gtaatcgctt gataagctct gttcgaccac cataaacttg atacggagca tcttctatta
     4801 cagctttctt tttatgccac cccacgttgc aactagagga ggtttatctt ctcgagacac
     4861 aactacctgt aaacacggca ccgttcggcc attcgtgcta gttgtggtag tcttatattt
     4921 agctaacatt ttattaatgg atgactcatg tttaaatgct aatgttttaa ggagtgatgt
     4981 ttccatatac caatagactt ttgagaacca tgacaaattt tgtgccaata tataatattg
     5041 aactagccct ctatattctt gttggtaagt ttgaacgata ctaaagtcat catcatgcaa
     5101 taagttatta cgatgaatag ctttaccatt tttcatgtat tggcggcatt tgctttcaat
     5161 aactgatgca ggtacaaata atgcgataac accattggca ctctgtctcc ctttgttatc
     5221 aatataatca ttgacacgtt gtgcttttat ctcatatccc agaaatttag ctgattctcc
     5281 agtcgcatgg gtaatcaaag tcttttcttg agaaagttcc aaagataact tagtatttaa
     5341 aaagtctcca atttgcttct ttatagcctt tgcctcagct tttgaacctg taaagcctag
     5401 aataaagtca tccgcatacc gaacatatct taatctccga tagctggtat cataagtatc
     5461 aactgaaggg agatttcttc tctcaacaat taactgatga gcttttttat aatctccttt
     5521 atcctgatag catttaattc ttctactcaa acgattatag gctgagtttg ctttctgctt
     5581 tttacctctt gtatattgag gtatcagctc ttcaccgacc cacttatcaa attgatgtaa
     5641 atagatatta gctaataaag gactaataac tccaccttgc ggtgttccac taatagtctt
     5701 gtgaaacttc caatcatcaa gatatcctgc ctcaagcata tttttgataa gcctaataaa
     5761 ccgaccatcc tgaatttgtc tagacaacat agtgattaat acatcgtggt caatcgtgtc
     5821 aaaataacta gagatatctc cttctatgaa ccaacgtgtc cctttccaag tctgaatttc
     5881 ttgtaaagct gtatgacacc ctctttttgg tctaaaacca tgagaatgtt cactaaattg
     5941 tggctcataa taggcttcta atatcatgcg aatcacttcc tgaagaagtt tatcactcca
     6001 tactggtatt cccaaaggac ggtgttttcc attcttttta ggaatgtact ctctcctagc
     6061 tggtctccag taataggttt cttgtcttaa ttgttcaata atcatatcta ttttttgaat
     6121 agacattcca tcaatcgttt cctctgtaac accctttgtc attgctccat tattcgggta
     6181 taactttgca taggctatca gatagagttc acgattaaat agtaacttat aaaccctttc
     6241 gagtggttta tcttgttttc cacgttcatg aatgaccgtt aaaatagttt tggctgtacg
     6301 catcccacgc acctaatcct ttctaactaa tcgaaattac ctgtcaccct tcgccatgta
     6361 caaggatttc ccttgctcgg actactacgg tgactccgtt accataaggg tcccccctct
     6421 taggcaatcc tgctattcgt taaaaatgta cgttctagta acccttaggt tcctcactca
     6481 ttcctttatt catacttatc gtatgctctt ttactgtaga aagttattcg tccaaaatca
     6541 caacaacgaa tatacagtaa catcggtctc agttactttc cgatgggcga tgctttgcac
     6601 ctagtcagaa ttgaggttca agcagtttag ccttaaccat aggttacgga acttgcggca
     6661 catcaaagcg ttgtaactca ctccttatcc gctttactaa catgctattg tcccctttgg
     6721 gtttccccgc taggttagtt agttgttcct attatttact ttcaataata tccctctgtg
     6781 agggagatac atttttacgc ttaacagcgc acaattttta gcatattatc tttgtcaggc
     6841 tctaccaccc tatttctcac atcatctgct ctttcagaaa ggctctttag aatttccttt
     6901 tgctcctcac ttggcaaggt cttaattact tcataatgtg cctcaggtgt tggaagattt
     6961 aacatatccg ctgtttgaat gtcagcgact tccttaaaca tagacattag ttcaggcaag
     7021 ttatagaact tggaaaatct tgtctttact ctgtatcctg ttccctccgg agaaagctca
     7081 aaagcagact gcgtttcccc aaaagtagaa gcccagctat caaaatgctc cagattattt
     7141 ttctttaagc tctcatactg aagataacgc tgcatagtgt aaagctcagt catggagttt
     7201 gatacaggcg ttcccgttgc aaagacaatg ccttttccgt ttgtcatttc atccatatag
     7261 cgacacttca taaacatatc ggaggactta aaggcttcac tttgaccgat tcctgcaaca
     7321 ttacgcattt ttgtataaag atagagattt ttgtagttgt gtgcttcatc aacaaagagc
     7381 ttatcaactc ctaattcctc aaaggtaatg acatcatctt tcttaaaatc gtcatttaat
     7441 ttctcaagcc ttgtttccag ttttttcttt gtcttttcaa gctgttttac tgtaaagttc
     7501 tgatttctgt catgcttgta ttcttctaca tagtttacga tttcatcaat ctgatcttgg
     7561 atatgcttct cctgatattc cttagacata ggaatttttt caaactgcgt atgcccgata
     7621 acaacggcat cgtattctcc tgtggcaatt cgaccgataa aacgcttacg gttcttcggc
     7681 tcaaaatctt tcttatctgc caccatgata tttgccgacg gatatagctg cataaactca
     7741 cgaccgattt gtcctgttaa gtgattgggt acaacaaaca aggacttact acacattcca
     7801 agtcttttac tttccattgc ggaagccacc atttcaaagg tctttccact gcccaccaca
     7861 tgagcaagca gggtgttgcc tccataaaga cttcttgcta tggcatttct ctgatgaggt
     7921 cttaaatcta ttttagtatt cattccctca aaggaaagat tacttccgtc atattctctg
     7981 tttcggatag agttaaaacg ctcattatac agttttacaa gacggtttct tctctcctga
     8041 tcattaaata tccagttctt aaattcttct tttagtagtt cctgcttttg ccctgcaagc
     8101 atggtttctt ttttatttag tacagaagtt ttagagccgt ccggatttac aatctggtca
     8161 aatacctttg tttctttcag gtttaaggca tcttcaatca gcttataggc atttaccctt
     8221 gatgtaccgt aagtcatttc agcgaggtca tttcctctat ccctactttt accttctata
     8281 ttccactcac ttgtcaggtt tgaaaactta accttaatat cccatcttgc atatcccgga
     8341 gttttcagcg tttcaaaaat aaatttttca atatctttaa tcggtatcca agtcgcacca
     8401 agacgaacac ttatctcact tgcttcaagc tcctttggta gaacttttgt aagctcagcc
     8461 ttttggtatt ccaaacgatt catctcatag ctaatcagct ctttttcttt accatcttct
     8521 gcatagccaa gatgaggtaa ctctctttcc gtctgtctga gctttgatag atagctatct
     8581 actatggcaa tcttgtccct gatattccca cttaaatatt catcctttgt tacatagccg
     8641 tatttgtagg aattactgcc attggcacag gcaaaaggca aatctccatc ttcggggtta
     8701 aaggatagag gtctataaaa gttttgttct tccctaatat ttaagtagat ttcccctcga
     8761 agctcctcaa tcaaagtcgg tctgtctttt cctgtaagac cttccatata gtcaaagtcc
     8821 acatatcctt tttcagatac cgataagaca agggcttcta aagaagtatc cacatgatct
     8881 atgactttag cctttgtaat agttcttttg gagaaaatat ctccctttgc cttaaagttt
     8941 tcttcatcaa ggatttcaat ggaggaaaca agcgggaagt tgctatcctc ttttaaagct
     9001 cttgtattgc ttaaattatt tacaaagcca tgcttattag aaaaacggtc atagacttca
     9061 tttagttttt cctgtgaagc cttgatttct tcctcactaa aaccttcttt ctgcttgtaa
     9121 atcacatttt ttaaggcagc attcagctca agataatcct tgattttttc tttgttttta
     9181 tcggttactt cctttttgat aaacagtgag ttttctctgt aatagacttc atcatcaata
     9241 atggtatagg aaaagttctt aacatcatcc gttgcaggga ttgaagtgat ttcatcatct
     9301 aaaagctcta tttcttcata cttggcatct tttgaaattc tttctcctgc aatctcgata
     9361 cgatccttta atgaagccat atttagctct gtgcctaaat aagatatcgg ttcacaagtt
     9421 agagtttttc caaatcttcc gcttacttca cgcattgagc caagtacctg ttcaggatga
     9481 tcaacaaagt atttgttata tacaagaccg ttttcatctt ccgcaaggtg tatccaatct
     9541 tcatcacgct ctaatacgct atctcttttc tttaagaaga taatatctga ggttacttct
     9601 gtgccggcag tacccttaaa ggtgtcatta ggaagtctga tagctcctaa aaactctgct
     9661 cttgctgcaa gatagcgtct tacactttca tcctttttat ccattgttcc acttgatgta
     9721 ataaaggcga taaccccgcc gtttctaacc ttatcaatgg acttggcaaa gaaatagtca
     9781 tgaataagga agttattacg attgtattcc ctgtcattta ctttgtattc tccaaaggga
     9841 acattgccga ttgcaacatc aaaaaagtta ttggaaaaag aagtttcttc aagtccttta
     9901 atctgtatat cactttcagg gtataaaagt tttccaatcc taccgcttat actgtcaagc
     9961 tctacaccat aaaactttga cttgttcatt tcatcaggaa gatttcctat aaagtttccg
    10021 atgcccattg atggctcaag gatatttccg ctcttaaatc ccatatcgga aagtgtctta
    10081 tatacgccgt caataacagt tttcggtgtg taaaagctcg ttagggtaga ttctcttgca
    10141 gcttcatatt ctgcctgaga taagttttcc tttagaaagc tcctcgcttc tttccactgt
    10201 ccgccttttt cttcatcgaa tacatcagca agtccacccc agcctacata ccttgctaaa
    10261 acttcctgag ctgtactgtc aaactctctt tgtccacttt cgatgcgact cagcatagag
    10321 atggcttcaa ggttattatt tagcctttca cttggagata acttgtcagg taatgtttct
    10381 tccgtaatct tgaagttatg agcttctgct ttctttattt cactttcttt agcaatagtt
    10441 tcaggctttt tatatgtcag attttcaaat accctctcaa gatcgctttc aagacgataa
    10501 ggaattacat ctgagcctgt tatcataccg ccaagatatt cggtattatc cttaaccgtt
    10561 accgtcttta gattatttcc catatcgtca aagcgtgtga tggtatagtc tttatccttg
    10621 tatttaattt catctccaac gataaacgca ggtctttcag ggcttacttg tcttaataaa
    10681 tcttcattat ctgtaaaggc tacaataggg atttgatggt ttccacttct tcccggatca
    10741 agccataagt catatctttc tgtgatttta ttttcagcaa tttcccttac agtatattct
    10801 tcatgattaa aatagacggt atcgccctct ttaactgcaa attcatctga aatacttttc
    10861 ttttcttcgt taagctctac ttcttccttc tccttcagat aatcaaatag tgtttcctga
    10921 acaggtgttg cagctactct ttcttccact tcttcagata tttcaagttc ttctttatct
    10981 tcaaagctaa gttctccgtt aaagactgat tgaagttcct gttcatccat ctgctttgca
    11041 agttctgtat ctttaagctc tctaaaagtc tttggaaaat cctctaaaat aagcctttga
    11101 gcatttaatt ctttcaattc ttcaagattg aaatatcccc attcaggttc aaatcctaac
    11161 acaagtccaa aggcatcacc gctttcccta tcatattccg tcatatacca agtccagtta
    11221 gaacggaaag gaataatata tgctgcatga acctctttat ccgctaaagc tacatcttcc
    11281 tgtgcgtaaa gctcaggcac tctttcaagc atttcatcag tcattaagtt ttcaggatta
    11341 tctttagaat aatattgtag ctcttttgat tcttctacct ctgacttact ttctattttc
    11401 ttttcttcat acagattttt agaaagcagc tcctctatac gctttgccac acttgaccaa
    11461 gtaagaaaaa catcattaca attattcttc tgtaatttaa gcccctttgc atcatgccat
    11521 tcatcacttc ccattgcccc cgatactgca tgacttctac cacctatgcc atattcgtct
    11581 tttaggaaat tagctttttc ctgcaaggta tgattttctt tgaaaaactt tgtaattcgc
    11641 tcttttcctc tatcgacgcc tcttcctctt gaaagacttt caaggacttc atcttctgta
    11701 atgaaggact ttaccttcgg aagctctgtt agattggtac tatattcctt tcgtgacagc
    11761 tcaagttcct gtaacctctg acaaaggcta tctaccttgt gatagtgaaa ccttaataca
    11821 tttctgtttt ctttgtatcc ttctaaaaac ctgctgtatt ctttgatcgt ttcctttagg
    11881 tagtcgggat tttttaatgc ttcagacaat ctttttgttt cttccggaaa gcctcttcca
    11941 cttgttttca atagttcaaa atatccttgt ccttcttcgc ttaaatcatg cattagatac
    12001 cataaggact ctgaaatctt atctctttca taatcaggag cctcagaaat ctctacattt
    12061 gtagcaaact caccattatc aagaagctca tttatcctct ttgcagcatc gctccagctt
    12121 aaaatttgcg tagtatcttc tcttgcagat gtcccgtagg ctaaatgaat gcctttatcc
    12181 gaataccagg aagatacttc tctttcatca atgtaaaatc cattaccgcc tctaaatata
    12241 tcttttaggt attctcctaa ttcttcatta ctttttcctt tagaaaactc agcgataaca
    12301 ggaagtctac ttccatcgtg atttcctccg ttaataagga cagtatctat atccctctga
    12361 gttaatggaa tggtaagtct catctgtcca tatgaatttt cgggtaaaga aaaagaagcc
    12421 ttttcagctt ctcttatctc tacctcagta ttatctttta aatttttaat acttccttga
    12481 ttgtcatttc cttcagagct gaaatcatcg ccccatactg cggatcgttc tcgtcctcta
    12541 tcttccaagc taccatcaat ttcggcttct ctgtcctcat aaagtctatc gcctgtttct
    12601 gaatatccat caggtgtcct gttagcttcc tctccttgta tagatccact aacatctcga
    12661 agtggctctg ctcctcgctc tctgaaaggt aatccagcct cattactgcg taggtcggat
    12721 tcggatactc ccttatgaag tccgtctgtt cctccaagct gtttagtgta ttctccctga
    12781 ttttctctat tatctcgtcc gtactctcca tttcggagaa ctcgctcatt ttcatttctt
    12841 tcctgatcat ctcgtcgaag tacatcatta tctcctttct caattttttc tttaatccta
    12901 ttatatcctg cttcttttcc tcttaaaact tctttttgaa gctcaagctc tttgcttttt
    12961 tgaatggttt catcaataat ctttccacta atatccgata cgatttcacc aagactcata
    13021 agggaaatgc tatcaagcat tgcaaagttt tcctttagaa gctcattatc cataggatag
    13081 tctacattaa atcttgaagc tactgcataa ctcactgagt ccctcacaaa cttggtaaaa
    13141 gatattctat cctcatcagc tattctaagc tcattcataa ggctgtctat cttttcatca
    13201 ccgtagagtc tacttaaaga aaagatattt tctaaggtgc tttcactttc ctcatagccc
    13261 tcgtttttta tcatttcctt taagacatcc ctatgagctt ctttatcaaa tctccaaaga
    13321 ttgacctcat tgacatccct atttcttgaa accgtctgac ttatatcaaa gatatatgcc
    13381 acttttttgt atgtgccgta gtcctctaaa atggggatac ctttttgtcc tctcataaca
    13441 gtacggttaa agcgttccct ccaatagtcg aacttggcac aggctgtcgc ttcagaattt
    13501 ctatcataaa tacttaactg acttctaaag tcatatcttt gattgtttcc gacaaccttt
    13561 aggagcttca ggtattctgc ttcactttgc aaaatatttt gttttacaag ctccaaaatg
    13621 ttatgaaaat catttattcg catttttacc tccttctttt tccaaacaaa aaaggcggtt
    13681 agattttact ctaatcacct tttgattctg tgtattgcaa cttgctgcaa cttaaatttc
    13741 ctactacaaa tcctcatttt atggtattca tagcaccctc ttatttataa aaatctttgt
    13801 tttgcaactt aattttattc attcagttcc cagtgtccgc tattaccact tcctacatac
    13861 ttcagattat ctatttcctt tatagctctt tcgatagtct ttacgctaac tccagcttca
    13921 tctgcaatag cctttcttgt aatcctatca ttgcttctca ctttttcttt aataaactct
    13981 gcgagagcta tcttatcgtg agcgacatcg tgagcgacac cctgagcgac atcgtgagcg
    14041 acattgtcgc ctccaacctt ttgtgtcgct atcttcttta gaggaataat cgttctgaat
    14101 atatctccct cctcaaatag cgggttttgt cctgaataaa gctgtgtgta tttgtaggta
    14161 tttcgcattc ctgaaccaag ttcatccgca agacctattt ctctaaaaac tttagatata
    14221 gcaggatttt taggaaatgg ctcaaacttc tgtaaatcta aagctcccat cccatgagcc
    14281 aagttgctgt tttcaactgt aatcctctca tcgtcaataa tcatctttgc aggaaaacca
    14341 cttgaataat ctctatgagc cagcgtattg gaaactattt ctctgagtat cctgtctctt
    14401 gcattgacat tgacaattcc gtccaagaca aataaatcat tcaagtgctt ttgtccaaat
    14461 tctatcagtc tgtcatagct gtcaatcaga tttgttatga caacatctct atcatcatat
    14521 ctatccttat tttcaaccct gaatatagca tcagttttgt gttgcggaag aacggacata
    14581 atagagttat cttttccaaa taacaaaata gcagctaatg tgattccttc acgctttgtt
    14641 tccggatctg tcagtatcaa attggcactt ctaagaagct cctcattact catattttcc
    14701 caaacatgat ttttatttcg gaaaacagcc attttcttag ctttatcaat gacagaagca
    14761 tcaagaaaat caatatcaag attcggatat accttattaa caaaatagct tccttgtttt
    14821 cttgcatata gcttatatac aagctctgaa tgatctgtga tattgatgtc cccttcataa
    14881 gacctatccc aaattcttcc gttatgtctg catacctgat aaccttcagg aactcttata
    14941 taaataactt gtttcccctc aatttcaaaa gtttccggca gcaaataaag tggtggatac
    15001 atcttttgcg gattgttgat tgccgtagta aattccttaa tcactttatc tactttatct
    15061 tcactaacac caacgatctc tcttttatca tttgcaccaa gtaaaatatg tccgccattt
    15121 ctattgttga aagagcatac tgtatcaaag acatctttgg ttaaagcgtt cttggattct
    15181 ttaaattcga catctatttt ttctccggct tgaattaact tcttaatttc atctatcgtc
    15241 atctgtttat ttcaccacct ttatttctta atgttttctt cgataaaaac attggaattt
    15301 tgaatttcaa ctctatcttt attaactaca aaagtaacat agtctccatt ttctaaattc
    15361 aaaagttccc taatcctctt tggaatagta acctgtcctt ttgacataac tttagcagta
    15421 tctataaatg tatctttcat gactaatccc tttcgcccta cttttcctac aaaagattat
    15481 agcactttta agatattttt tctactctga aattagtgtc atcttactta ctataagttg
    15541 aaaccgcttc ttttatctca ttttcaatcg cttctaaaaa ttcttccttt gaagatttcc
    15601 cttgagcaat atcggataat tccatttccc attttgcggt agtttctgcc gacttaaagt
    15661 tatcagctac aatcgctaca aggcttattc ctttatgtgt ggctataagg tttttcttat
    15721 ctctttctac aaatccctta aagattaagt tttcaataat ccctgccctt gtgaactg
//
LOCUS       DARYNN010000047        15359 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.047, whole genome shotgun sequence.
ACCESSION   DARYNN010000047 DARYNN010000000
VERSION     DARYNN010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15359)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15359)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15359
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.047"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            376..2016
                     /locus_tag="TVB59_001553"
     CDS             376..2016
                     /locus_tag="TVB59_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL1010425.1"
                     /translation="MKKTMKKMLAASTLCIIMSGSFISGSARVLAEEYYGWNDVTGSK
                     SPFPLYVTPKNGDKNIKVQQTVVYCFNRDGQWPENWEKRIYESPDKVPHKLPEYNKKS
                     GSDNLFQLLNPKIKIKNPMAALLAVLEDGYPTSSSSGVNQRTTQLAIWHFTDGLSNLA
                     QFHLTPEETSAYNKLIEKGTNASNQSENKLLNKTLDIYSYIDGTGDKKHNYQHLLGST
                     PIPIDNSKENKCQCTKVDLMRTGDGVKIIVYVDNNGNNRYDNGDKMLKEETIKHGQRG
                     PAGESGKPGPKGDRGETGARGPAGPQGKPGKQGPRGDKGETGERGPQGEKGEPGTPGP
                     KGEDGKDGAPGRDGQPGPKGEKGDPGKDGQDGKPGEKGEPGIPGPKGEDGKDGAPGRD
                     GQPGPKGEKGDPGKDGQDGKPGKKGDPGRDGKDGEKGERGEQGPKGERGEQGPQGERG
                     EQGPRGENHTPTPDPMPEPAPKPESKPEPKPTPQPEVKPLPETKPQKPTKPSAMASQP
                     SSKALPKTNDTSGLMTVLGTGLLSLLGLGFLAKRKRKQ"
     gene            complement(2260..2949)
                     /gene="rplA"
                     /locus_tag="TVB59_001554"
     CDS             complement(2260..2949)
                     /gene="rplA"
                     /locus_tag="TVB59_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004232886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEL1010426.1"
                     /translation="MAKKSKQMRAALEKVDSTKAYSVEEAVALAKETNFAKFDASVEV
                     AYNLNIDVRKADQQIRGAMVLPNGTGKTQRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINGGWLDFDVVIATPDMMAIVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADKAGNVQAIIGKVSFDADKLVENFKAFHEVMVKAKPATAKGTYMTNVSITTTQ
                     GVGIKVDPSSF"
     gene            complement(3055..3480)
                     /gene="rplK"
                     /locus_tag="TVB59_001555"
     CDS             complement(3055..3480)
                     /gene="rplK"
                     /locus_tag="TVB59_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEL1010427.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFDFITKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANIEAAMRMIEGTARSMGFTVTD"
     gene            3716..4513
                     /locus_tag="TVB59_001556"
     CDS             3716..4513
                     /locus_tag="TVB59_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1010428.1"
                     /translation="MHKKVTIKDVAREAGVSVATVSYVINNREDQKISPETRNKVLQM
                     INLLNYRPNQAAKSLVTQKRQLIALYYKEHSSVLKRAEQLHFITQLSAFLYTKHYHLI
                     CLNQEYIGKYDVADVILTLEVTKEEFYKIGNSNFVPLIAIDSIIDDPLFFQINSDPHL
                     LFNKASAYFAGEPFELVSLPIQNQEITQGLAQQFDNICWIHSICDIESVSKGNILVID
                     DTVNHILSKHKNKLYLPSISEAKLLKLFQAIEWASKREAINNHNILV"
     gene            4668..5018
                     /locus_tag="TVB59_001557"
     CDS             4668..5018
                     /locus_tag="TVB59_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEL1010429.1"
                     /translation="MIIYKLTALAFIILTPLFSMIMISLLRLGRRGLKFPDLALPLFV
                     FEIVIVSGKFFTHHLLPYYLIVMSLLAIVMALLLIIRIQQFSYRRFFKLFWRVGFLVT
                     LLFYLMLVGLIFIV"
     gene            complement(5347..5802)
                     /locus_tag="TVB59_001558"
     CDS             complement(5347..5802)
                     /locus_tag="TVB59_001558"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010430.1"
                     /translation="MTISDQKVNASQYRWRQYYYRMSPTERELKKEKEVLRNFIATIK
                     LSYSEANEMEAKVYGADSFSKLRAIKEELQSLKSRYFKISNKVEIVSSLIDEHFPEGH
                     SRNIMKKYRLEFLDRLMGIQYDVGLNKDRALDDLSERIIMTRKKLWYIQ"
     gene            complement(6177..8576)
                     /locus_tag="TVB59_001559"
     CDS             complement(6177..8576)
                     /locus_tag="TVB59_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEL1010431.1"
                     /translation="MARRTQRQKNPPKRRLTKAELEKQKAIKRMIASFSCALLLVFAM
                     LRLGALGVTLYNLIRFMVGDLANLLMLAVLFYLFFFKWLRQKDGLIAGFIILFLGLLV
                     EWHAYLFSLPQLAHQAIVAGTIQLITNDLLAFKVSEFVGGGMLGAMLYKPISFLFSNI
                     GSYFIGFLFILLGLFLMTPWDIYDVSHFVKTLFEKLSLAYQENKEKRFVEREKQRLLA
                     EEERLAREALEEQEYLANQAINPETGELLAEPEDLLMEMADQKESEAFFEPEILAYDS
                     HPADDEPEAFGDEEESVPEAPLTGASAIAGEAPLSDDEELSVEVDFTPKTNLLYKLPT
                     IELFAADKPKNQFKEKYLVRQNIKVLEDTFRSFGIDVKVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLADDLALALAAKDVRIEAPIPGKSLVGIEVPNSEVATVSFRELWEQSNTS
                     DDKLLEIPLGKAVNGSARSFDLTRMPHLLVAGSTGSGKSVAVNGIISSILMKARPDQV
                     KFLMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFSKVGVRNI
                     AGYNAKVEAYNKQSEQKQIPLPMIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRIAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVSFIKEQAEADYDDYFDPGEVSDSDYGSSGAPEGDP
                     LFEEAKALVLETQKASASMLQRRLSVGFNRATRLMDELEEAGVIGPAEGTKPRKVLQT
                     N"
     gene            8696..8869
                     /locus_tag="TVB59_001560"
     CDS             8696..8869
                     /locus_tag="TVB59_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010432.1"
                     /translation="MEKEFNTLTYGKLPLQIDMGHGKLIPKGVEVKAIVDMQTGQVTF
                     KVSQEDLEKLRNS"
     gene            8956..9762
                     /locus_tag="TVB59_001561"
     CDS             8956..9762
                     /locus_tag="TVB59_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEL1010433.1"
                     /translation="MKKLLSFGLIGLALLSLSGCESIDRAIKGDEYVDEKIAREESET
                     AAKAYEAKIKKALKADADQFPQLNKEVDKDEAKVIIKTNQGDITLKLFPKYAPLAVEN
                     FLTHAKEGYYDKLLFHRVINNFMIQTGDPKGDGSGGESIWKGKDSKKDAGQGFANEIS
                     PFLYNIRGALAMANAGADTNGSQFFINQSKLNQAKALSIDNYSKPIIDSYEEGGNPSL
                     DGGYTVFGQVIEGMDIVDKIAASPVGPNDKPIENITINAIDIVKDYSFKK"
     gene            complement(9918..10751)
                     /locus_tag="TVB59_001562"
     CDS             complement(9918..10751)
                     /locus_tag="TVB59_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEL1010434.1"
                     /translation="MYLKFFEGLMSYHFLQNALITAVVIGIVSGAVGCFIILRSMSLM
                     GDAISHAVLPGVALSFILGINFFVGAIVFGLLASVIITYIKENSVIKGDTAIGITFSS
                     FLALGVILIGIANSSTDLFHILFGNILAVQDSDKWITIIVSVFVLAIIVLFFKELLIT
                     SFDPVLARSMGMKVTAYHYLLMILLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKVMLVISSCLGAMTSVLGLYLGYTFNIAAGSSIVLTSAVVFLISFFVSPKQGYFKKH
                     S"
     gene            complement(10752..11477)
                     /locus_tag="TVB59_001563"
     CDS             complement(10752..11477)
                     /locus_tag="TVB59_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEL1010435.1"
                     /translation="MIDTQNLSVSYNGNVKALDNISLQIKGPAIVGIIGPNGAGKSTL
                     MKAMLNLLDYSGQVTVDQKDGRRLGHTIAYVEQRSMIDYNFPITVKECVSLGTYTRLG
                     LFRRVGKKEYDQVDQLLEQVGLAGFGNRPIKSLSGGQFQRMLVARCLIQESDYIFLDE
                     PFVGIDSVSEKIIIDLLKDLKKAGKTILIVHHDLSKVEHYFDELVVLNKELIAYGSVD
                     EVFTVETLSKAYGDHLFLGKGMF"
     gene            complement(11537..12469)
                     /locus_tag="TVB59_001564"
     CDS             complement(11537..12469)
                     /locus_tag="TVB59_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HEL1010436.1"
                     /translation="MKKKLSLALSAFLAVFMLVACSNGGNKEAKSDKLKVVVTNSIIA
                     DMTKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVEKTSNADLILYNGINLEDGGQAWFT
                     KLVKNAKKEKDKDYFAVSDGIDVIYLEGESEKGKEDPHAWLNLENGVIYSKNIAKQLI
                     AKDPKNKETYENNLKAYVEKLEKLDKEAKSKFDAIADNKKLIVTSEGCFKYFSKAYGV
                     PSAYIWEINTEEEGTPDQISSLIEKLKDVKPSALFVESSVDRRPMETVSKDSGIPIYA
                     EIFTDSVAKKGQDGDSYYAMMKWNLDKISEGLAK"
     gene            12615..13262
                     /locus_tag="TVB59_001565"
     CDS             12615..13262
                     /locus_tag="TVB59_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEL1010437.1"
                     /translation="MTPNKEDYLKCIYEIGEQNIKISNKMVAERMKVSAPAVSEMIKK
                     MIAQGWIVKDKTCGYYLTEQGQRLVANLYRKHRLMEVFLIHQLGYTAREVHQEAEVLE
                     HTVSDMFIDRLDKTLGYPTFCPHGGTIPRRQQPLIEINKTTLNTIKELGIFRLSRVHD
                     HFELIQYLEAHQLTINSEFRLIQIDDFAKTYTITYADKELIIPENIAKQLFVTAI"
     gene            complement(13318..14019)
                     /locus_tag="TVB59_001566"
     CDS             complement(13318..14019)
                     /locus_tag="TVB59_001566"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEL1010438.1"
                     /translation="MKIGIIAAMEEELRFLLEQLHDSQEHQVLSNTYYTGRLGRHELV
                     LVQSGVGKVMSAMTVAMLAEHFQADAIINTGSAGAIASGLAIGDVVVADRLVYHDVDV
                     TAFGYDYGQMAAQPLYFDSDSKLVETFKQVLDQEKTNSRIGLIATGDSFIAGQDSIDT
                     IKAHFPETLAVEMEGAAVAQAAQAAGKPFIVVRAMSDTAAHDANMTFDQFIVEAGKKS
                     AKVLIAFLEALPDKK"
     gene            complement(14043..14291)
                     /locus_tag="TVB59_001567"
     CDS             complement(14043..14291)
                     /locus_tag="TVB59_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010439.1"
                     /translation="MGKPLLTDDIIEKAQRGEQFEPDDYADFETKIMTFEDKHTDRIY
                     KSRRIENAKRSRFQSRLNLILLAVLVLIALLVYAVFNL"
     gene            complement(14291..14845)
                     /locus_tag="TVB59_001568"
     CDS             complement(14291..14845)
                     /locus_tag="TVB59_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEL1010440.1"
                     /translation="MDFEEKTIKRQEIFDGHIFKVAVDDVQLPNGLGQAKRELIFHRG
                     AVAILAVTPERKLLIVKQYRKAIEAISYEIPAGKLEVGEANSALEAAARELEEETAYS
                     GDLRLIHEFYTAIGFCNEKIKLYLATDLQRVANPRPQDADEVIELLELSYQECMDLVA
                     QGKLVDAKTIIALQYYALHFGGDV"
     gene            complement(14876..>15359)
                     /gene="glmU"
                     /locus_tag="TVB59_001569"
     CDS             complement(14876..>15359)
                     /gene="glmU"
                     /locus_tag="TVB59_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016740.1"
                     /note="forms a homotrimer; catalyzes the acetylation of
                     glucosamine-1-phosphate and uridylation of
                     N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc;
                     function in cell wall synthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEL1010441.1"
                     /translation="SRLGEGVVVSQSVIEDSVLADGVTVGPYAHIRPDSQLDESVHIG
                     NFVEVKGSHLGANTKAGHLTYLGNAEIGSEVNIGAGSITVNYDGQRKYQTVIGDHAFI
                     GSHSTLIAPVEVGENALTAAGSTIAQSVPADSVAIGRSRQVVKEGYAKRLPHHPNQAK
                     "
BASE COUNT         4726 a         3425 c         2896 g         4312 t
ORIGIN      
        1 tagaaaaagc cagaaggcta caaataagca aatcgtcaaa atcatgaaca cttcaggctt
       61 gctgaggaat attttctaat ggttattaga aataatgaac aattacctaa caaaagactc
      121 caaaataaag gtaaaagacg aacattcacc ttgctgctca gctaccaaga caaacaatcc
      181 tgatagcatc aattttcttt aggctcttag caattagttg caatatcaga taattttgaa
      241 tttaattaaa aaaaacgaaa ctacggagac caattatcag aaagctattc acagccagca
      301 aagggcatgc taaagtatta tctggaaaaa gaaaggctta ggaatgatta tttctaaact
      361 aaaaggagag agacaatgaa aaaaacaatg aagaagatgc tagcagcctc gacgctctgt
      421 atcatcatgt caggcagctt catcagcggc tcagctagag tgttagcgga ggaatattat
      481 gggtggaatg atgtcactgg gtctaagtca ccatttcctc tatacgtgac accaaaaaat
      541 ggagataaaa atataaaagt tcaacaaacg gttgtttact gttttaacag ggatgggcaa
      601 tggccagaaa attgggaaaa acggatatat gaatctcctg ataaagttcc acataaatta
      661 cccgaatata ataaaaagtc aggaagcgat aatctgtttc aattacttaa tcccaaaatt
      721 aagataaaaa atccaatggc agctttatta gcggttttgg aagatggata tcctacgtca
      781 tcttcttcag gagtaaatca aagaacaact cagctagcta tttggcattt tacagatgga
      841 ttaagcaatc ttgcccaatt tcatcttact ccggaagaaa cttcagctta taacaagttg
      901 atagaaaaag ggacaaatgc ttctaatcaa agtgaaaata aactattaaa taaaacttta
      961 gatatttatt cctatataga tgggactggt gataagaaac acaattatca acaccttctt
     1021 ggctccactc caattcctat tgataattct aaagaaaata aatgtcaatg tacaaaagtt
     1081 gacttaatgc gaactggaga tggggttaaa atcattgttt atgttgataa caacggaaat
     1141 aatagatatg acaacggcga caaaatgcta aaagaagaaa ctatcaaaca tggtcaacgc
     1201 ggacctgctg gtgaatctgg gaaaccaggg cctaaagggg atcgaggaga aactggagca
     1261 cgcgggccag ctgggcctca gggcaaacct gggaaacaag gacctagagg tgataaagga
     1321 gaaaccggag aacggggacc tcaaggggaa aaaggtgaac ctggaactcc tggtcctaaa
     1381 ggagaagacg gtaaagacgg ggctcctggg cgtgacggac aaccggggcc taagggtgaa
     1441 aaaggtgacc ctggaaaaga cggacaagat ggaaaaccag gggaaaaagg agaacctgga
     1501 attcctggtc ctaaaggaga agacggtaaa gatggggctc ctgggcgtga cggacaaccg
     1561 gggcctaagg gtgaaaaagg tgaccctgga aaagacggac aagatggaaa accagggaaa
     1621 aaaggtgacc ctggacgcga tggtaaagat ggagaaaaag gcgaacgcgg tgaacaaggg
     1681 cctaaaggag aacgcggtga gcagggacct caaggagagc gtggggagca aggacctcgt
     1741 ggggaaaatc atactcctac cccagaccca atgcctgagc cggcacctaa accagaatcc
     1801 aaacctgaac ctaagccgac acctcaacca gaggttaagc ctctgccaga gactaaacct
     1861 caaaaaccaa ccaagccgtc agcaatggct agccaaccaa gtagcaaagc actaccaaaa
     1921 acaaatgaca ctagcggctt aatgactgta cttggaacag gcttgctctc tcttcttgga
     1981 ttaggcttcc tggcaaaacg caaaagaaag caataactaa cacataatca ttagtaatcc
     2041 attcattatc catttacaag ttatcataaa aaagccttat cattccttga ctggtatgat
     2101 aaggcttttt gtttacccta tatagctcta cccttactcc aaaaatcact taaccctagg
     2161 aaaaggctga ctatcatttt tggccaaaaa aagacagaca ccaattcatg atgtctgtct
     2221 caaaaccaat cccttttagg gtcagtcctt aattacttat taaaatgaac ttggatctac
     2281 cttgataccc acaccttgtg tagttgtgat agatacgtta gtcatgtaag taccctttgc
     2341 agtagctggc ttagccttaa ccattacctc atggaaagcc ttaaagtttt caaccaactt
     2401 gtcagcgtca aatgatactt taccaatgat agcttgtacg ttacctgctt tatcagcacg
     2461 ataggtaatt ttaccaccct tagactcttc aaccgcctta gcaacgtcca ttgttactgt
     2521 accagtttta gggtttggca tcaagttacg aggtccaagg acacgtccaa gacgtccaac
     2581 aatagccatc atatctggtg ttgcaataac aacatcaaaa tcaagccagc cgccattgat
     2641 cttagcaaca aggtcatctt caccaacgaa gtctgcacca gctgcctttg cttcttcagc
     2701 ttttgctcca cgagcaaaaa caaggacacg ctgagtttta ccagttccgt ttggcaacac
     2761 catcgcacca cgaatttgtt ggtctgcctt gcgaacgtcg atgtttaagt tataagcaac
     2821 ttctacagaa gcgtcaaatt ttgcgaagtt agtttctttt gcgagtgcta cagcttcctc
     2881 tacactgtat gcctttgtgc tgtccacttt ttcaagtgct gcacgcattt gtttgctttt
     2941 tttagccatt tttatcttct ccttgtaatg tggtcatatc gatttgattt aaaaatctcc
     3001 cacgtcactc atctctatga tgaagtcttg cgggtaataa gggcaggttg ctgattaatc
     3061 agtaacggtg aatcccatag aacgagcagt accttcaatc atacgcattg cagcttcaat
     3121 gtttgcagcg tttaaatctg gcatcttagt ttcagcaatt tcttgtactt gtgcacgagt
     3181 aactgtcgca actttagttt tgttaggtgt acctgatcct ttttcaacac ctgcagcctt
     3241 ctttaaaaga acagcagctg gtggtgtctt tgtgatgaaa tcaaatgatt tgtcttcgta
     3301 aactgagata acaaccggga taatcatacc agcctgatca gctgtacgag cattaaattc
     3361 cttagtgaat cccatgatgt tgatacctgc ttgaccaaga gctggtccaa ctggtggagc
     3421 tggtgtcgct ttaccagcag ggatttgaag ttttacaagt ttttcgactt ttttagccat
     3481 ttttaaaaat cctcctgttg tggttttggc ggtaattcac gatttttacc tcccacaggt
     3541 atgctagagc ataccttacc attatacctt attagacaga taaatcaagt cattttcaca
     3601 aaaatgttac cgcaaatagc agatgtctcc tatggcacta gcagtacaag catgtgaggc
     3661 ttccaaggag ccgcttctag ttgactttta agcgtttttt tattataaca aagctatgca
     3721 taagaaagtt acgatcaaag atgtcgcacg cgaggcggga gtttctgtgg ctactgtctc
     3781 ctatgtcatc aataacagag aagatcaaaa aattagccct gaaacgcgca ataaagtgct
     3841 gcaaatgatt aatcttttaa attatcggcc aaaccaagcc gcaaaatcac tcgtgacaca
     3901 aaaaagacag ctaatcgccc tttactacaa agagcacagc tctgttttaa aaagagcaga
     3961 gcagcttcac tttatcaccc agctatctgc ctttctttac acaaagcact atcacttgat
     4021 ttgccttaat caagaataca tcggaaaata tgatgtagca gatgtcattc tcaccctaga
     4081 ggtcaccaaa gaggaatttt acaagatcgg aaatagcaac tttgttcctt tgattgctat
     4141 tgatagtatt attgatgatc ccttattttt ccagattaat agtgaccctc atctcctgtt
     4201 caataaagcc agtgcttatt ttgcagggga gccctttgaa ctggttagcc tgcctattca
     4261 aaaccaagaa atcactcaag gactcgctca acagtttgat aacatttgct ggattcactc
     4321 tatttgcgac atcgaaagcg tgtctaaggg gaatattcta gttattgatg atactgtcaa
     4381 tcatattctt agtaagcaca agaacaaact atacctgcca agtatctcag aagctaagct
     4441 tctgaagctt tttcaggcta ttgagtgggc ttccaaaaga gaagcaatca acaatcataa
     4501 tattttggtt taaccatgat aagagcttag caacaagctt gctgctaagc tctttttgtt
     4561 ggtcaagagg ccaactttat ttaggtatca gtcagtgtgc cagctctttt agccactaaa
     4621 agcaggaatt agtttacaag tctaccaatt gggtataaaa tagacttatg atcatctaca
     4681 aattaacagc cttagccttt attatcctga ctcccttatt ctctatgata atgatatccc
     4741 tattgagact gggacgaaga ggccttaaat ttcctgattt agccttacca ctttttgttt
     4801 ttgaaattgt tattgtatca ggaaaatttt tcacccatca tttactacct tattacctga
     4861 ttgttatgtc cttgttggcc attgttatgg cactcttact gattatcaga atccagcagt
     4921 tttcttaccg ccgatttttc aaactatttt ggcgagtagg ctttttagtc acactactct
     4981 tttacctgat gctagttggt cttattttta tcgtttagtg ccttaccaga catggcttca
     5041 agcctagcag tctgaatctg ccaattaact ctagcactat cactcaaaag gaagctgtct
     5101 ttgaactttc tgcttgagtg ggactttttt caaagcaatc aatccatatc aaaccagcat
     5161 tagagcatgc ggcttgatac ggattgattg ctttaagaac tgttgtaaaa tatcaaaaat
     5221 tcagttttta ataaagtcca ttagctattt ctacactaaa tatcatttaa gaaaacagag
     5281 gctaataact agagttcact ataacctaaa atcaccaata cctccgatta acttaattta
     5341 accaaactac tgtatatacc aaagtttttt acgtgtcatt ataatacgtt cagataaatc
     5401 atctaatgca cgatctttgt tgagaccaac atcatattga atacccatta atctatctag
     5461 aaactcaaga cgatatttct tcataatatt tcgtgagtgt ccttctggaa aatgctcatc
     5521 aataagcgaa cttacaatct caactttatt actaatttta aaatagcgac ttttcaaaga
     5581 ttgtaattct tctttaattg ctcttaattt agaaaaacta tctgctccat aaaccttagc
     5641 ttccatttca ttagcctcag aataacttag ttttattgtt gcaataaaat ttctaagtac
     5701 ttccttctct tttttaagct ccctttctgt cggactcatt ctatagtaat attgacgcca
     5761 acgatattga gaagcgttga ctttttgatc acttatagtc aaaatagtca atgctactac
     5821 actaaagaaa aatattcttt tcgtttgcag tttctcctat acttcataat gtactatttg
     5881 tatataaaca caacataacc aagcattagt atatcagaaa actttcttaa atatgtgata
     5941 ttagctaatc tttttttaaa actctctata tattaaggta ttatggacat attgacttag
     6001 cagattagat ctgccaatta gctctagcac tatcactcaa aatgaagctg tctttgagtt
     6061 ttctgcttga gtgggacttt ttcaaagcag catatcaaaa acccgtatca agccacatgg
     6121 ttaagcttag cttggtacgg gtttgtttta tgatgagcct ttagatgagc tcttttttaa
     6181 ttggtttgca gtacctttct tggcttagtc ccctcagctg gaccaatgac accggcctct
     6241 tctaattcgt ccattagtcg agttgctcgg ttaaagccaa ccgatagacg cctttggagc
     6301 atcgaggcgc ttgccttttg cgtttccaat acaagagcct ttgcttcctc aaaaagggga
     6361 tcaccctcag gagctccgct gctgccataa tcagagtcac taacctcacc cggatcaaaa
     6421 taatcatcat aatcagcctc tgcctgctcc ttgataaagc taacaatgcg ctcaacatca
     6481 tcatctgaaa taaaggagcc ttgcagacgc acagggtgat tctcatcaat cggcttaaag
     6541 agcatgtccc cgcgaccaag cagcttttca gcgccatttt catcaagaat ggtgcgacta
     6601 tctgttcctg atgaaaccgc aaaggcaata cgtgatggaa cattagcctt aatcaatcca
     6661 gaaataacat caacagaagg tctctgagta gctaaaatca tatggatacc tgctgcacgc
     6721 gccttttgcc caagacgaat aatagcatcc tcaacctcct tactagccac catcatcaaa
     6781 tcagctagct catcaacaat aacaacaatc atcggcaaag ggatttgctt ttgctcagat
     6841 tgcttgttgt aggcttcaac cttggcattg tagcctgcaa tatttcggac accgacctta
     6901 ctgaacagct catagcgatt ttccatctca tcaacaacct tctgaagcgc tttgcttgct
     6961 ttacgagggt tggtgaccac cgggattaac aggtgaggaa tgtcattata aacagacagc
     7021 tcaaccattt tcggatcgac cattaggaat ttgacctgat ccggtctagc cttcattaaa
     7081 atactggaga taataccgtt gactgcaaca gatttccctg atcctgttga gccagccacc
     7141 agcaaatgag gcatgcgggt caaatcaaag cttctggcac taccgttgac agccttacca
     7201 agaggaattt ccaataattt gtcatcagat gtgttggatt gctcccaaag ctcgcggaaa
     7261 gaaaccgttg caacctctga atttggtacc tctataccca caagggattt gccagggatc
     7321 ggagcttcaa tccgtacgtc cttggctgcc aaggccaagg ccaagtcatc agctaaattg
     7381 gaaatgcgat tcacacgaac accaacagcc ggcttaacct cgtatttagt tacagatggc
     7441 ccaatctctg cccgctccac cttgacgtca attccaaagc ttctgaaggt atcctctaat
     7501 accttgatat tttgacgaac aaggtacttt tccttgaatt gatttttagg cttatcagca
     7561 gcaaacagct ctatcgtcgg cagcttgtaa agcagattgg tctttggcgt gaaatcgacc
     7621 tccactgaca gctcctcatc atctgacagc ggcgcctctc ctgcgattgc tgaagcaccc
     7681 gttagagggg cttctggtac agactcctct tcatctccaa atgcctcagg ctcatcatca
     7741 gcagggtgtg agtcataggc cagaatttcc ggctcaaaaa atgcttcaga ctccttctga
     7801 tcagccatct ccatcaatag gtcttctggc tctgctaaaa gctcacctgt ctcaggatta
     7861 atcgcttgat tggccagata ttcttgctcc tccaaggcct ctcttgctag acgctcctct
     7921 tcagccagca atcgttgctt ttctcgctca acaaaccgct tttccttgtt ttcttgatag
     7981 gccagggata gcttttcaaa aagcgtctta acaaaatgac tgacgtcata aatatcccaa
     8041 ggggtcatta aaaacaagcc cagcaggata aacaaaaaac caataaaata agagccaata
     8101 ttagaaaaca agaaggaaat aggcttgtac agcatggccc caagcatacc accaccaaca
     8161 aactcgctaa ccttaaaggc tagcaggtca ttggtgatta gctggatagt cccagcaaca
     8221 atagcctgat gagctagctg aggcaatgag aaaagatagg catgccattc aaccagaagc
     8281 cctaaaaaca agatgataaa gccagcgata aggccatctt tttgcctgag ccacttgaag
     8341 aaaaagaggt aaaaaaggac cgccaacatc aagagattgg ctaagtcgcc aaccataaag
     8401 cgaataagat tatataaggt aaccccaagc gcacctaagc gaagcatggc aaaaacaagc
     8461 aataaagcgc aggagaaaga agcaatcatt ctcttaatag ccttttgctt ttcaagctct
     8521 gcctttgtta aacgtctctt agggggattt ttttgtcgtt gagttcttct agccatagcc
     8581 ttattataac attttttaat cgttatgaaa gatgacatta aaattctcaa taaatagatg
     8641 aagctgcttg attttatgct ataatgtcaa tcataagaac aaataggagt tgaagatgga
     8701 aaaagaattt aacaccttga cctatggtaa gcttcccctg caaattgata tggggcatgg
     8761 caagctaatt cccaaaggag ttgaagtcaa ggctatcgtt gatatgcaga ccgggcaagt
     8821 caccttcaag gtttctcagg aggacttaga gaagcttaga aatagttaaa aaatagactt
     8881 cgtctcaatg ccctttagct ttattttcca agtcatttta tgttaaaata aaagaaattg
     8941 ttctaaggag tacacatgaa aaaactacta tcttttggct taatcggtct tgctttgctt
     9001 agcttaagtg gctgtgagtc cattgatcgt gctattaaag gtgatgaata cgtcgatgaa
     9061 aaaatcgcta gagaggaaag cgagacagca gcaaaggctt atgaagcaaa aatcaaaaaa
     9121 gcactcaagg ctgacgctga tcagtttcca caattaaata aagaagtcga caaagacgaa
     9181 gctaaggtca ttatcaaaac taatcagggc gatatcaccc tcaagctctt ccccaagtat
     9241 gcaccgcttg ctgttgaaaa ctttttaaca cacgccaagg aaggctatta cgacaaactt
     9301 ttgttccatc gggtgattaa taactttatg attcaaaccg gtgatccaaa gggagatgga
     9361 tctggcggag aatccatttg gaagggcaag gacagcaaaa aagatgcggg acaaggcttt
     9421 gctaatgaaa tctcaccatt tttatataac attcgagggg ctcttgctat ggcaaatgcc
     9481 ggtgcagata ctaatggcag ccagttcttc atcaatcaaa gcaagctcaa ccaagccaag
     9541 gccttatcaa ttgataatta ctctaagcca atcattgact cctacgaaga agggggtaat
     9601 cctagcctag atggtggcta taccgttttt ggtcaggtta ttgagggtat ggatatcgtt
     9661 gataaaatag ctgccagccc agtcggccca aatgacaaac caatagagaa catcactatt
     9721 aatgctattg acattgttaa ggattactcc tttaaaaaat agcctctaag ctacaacaac
     9781 aataaaacga ccagctcctt atcggaaaag ccaccgattc aagagctggt cgtgattttt
     9841 tgctatcaat taaataaaga agctagccta ttgatcatat cattagcagc tatccattca
     9901 cagccagcta tggtttacta ggaatgcttt ttaaagtagc cctgcttagg cgaaacaaag
     9961 aagctaatca gaaacaccac agccgaggtc aaaacaatgc ttgagcctgc tgcaatatta
    10021 aaggtgtagc ccaaatagag ccccaacaca gaggtcatag ctcccaagca tgaggagata
    10081 accagcatta cctttaggct gttagcatac aaatacgctg tagccgctgg cgtaatcagc
    10141 atcgccacaa tcaaaatggt accaacactt tgcatagcag tcaccgaaac caaggtcaac
    10201 aaaatcatca acagataatg ataagcagtg accttcattc ccatagacct tgctagcaca
    10261 ggatcaaagg aggtaatgag taattcctta aagaagagga caataatagc caaaacaaaa
    10321 accgaaacaa tgatcgtaat ccatttgtca ctgtcttgca ctgctaggat atttccaaag
    10381 aggatatgaa aaagatccgt tgagctatta gcaatcccaa tcagaataac ccctaaggca
    10441 agaaaagagc taaaggttat ccctattgct gtgtctccct tgataacaga gttttccttg
    10501 atgtaggtaa tgataacaga ggctagcaag ccaaagacaa tagcccctac aaaaaaatta
    10561 atccctaaaa taaaggacaa ggctactcct ggcaaaacag cgtgagaaat cgcatcaccc
    10621 attaatgaca tggacctaag gataataaag cagcctactg ctcctgatac aataccaata
    10681 acaacggctg taataagggc attttgtaaa aaatgatagg acatcaggcc ctcaaaaaac
    10741 ttcaaataca tttaaaacat tccctttcct aagaatagat gatcaccata ggcctttgat
    10801 agggtttcaa cagtgaacac ctcatcaaca gatccataag cgatcagctc tttgttcaat
    10861 accactaact catcaaagta atgctctacc ttgcttaaat cgtgatgaac aattaaaatc
    10921 gttttgcctg cttttttcaa gtccttgagc aggtcaatga tgattttttc actaaccgaa
    10981 tcaatcccaa caaagggctc atcaagaaaa atatagtctg actcctgaat caagcatcta
    11041 gctactagca tacgctgaaa ctgaccacca gaaagagatt ttatcggacg attaccaaag
    11101 ccagcaagcc caacctgctc tagcagctgg tcaacctgat catattcttt ttttccgaca
    11161 cgacgaaaaa gccctagcct agtgtaggtc cctaatgaga cgcactcctt caccgtaatt
    11221 ggaaagttgt agtcaatcat gctgcgctgc tctacataag caatcgtatg ccccagcctt
    11281 cgaccgtcct tttgatcaac agttacttgg ccactataat ctaaaagatt gagcatagcc
    11341 ttcatcaagg ttgattttcc tgcaccattt ggcccgataa tcccaacgat agctggtcct
    11401 ttgatttgta gtgagatatt gtctaaggct tttacgttac cgttatagct aaccgaaaga
    11461 ttttgcgtat caatcatttt ttctccttaa tacaaacaaa gcacaacacc agaagctgct
    11521 gtgctttatt gttatattat tttgctaagc cttcagaaat tttatcaagg ttccatttca
    11581 tcatggcata gtagctgtct ccatcttggc cttttttggc tacagagtca gtaaagattt
    11641 ctgcatagat cggaatacca ctgtccttag aaacagtctc cattggacgt ctgtcaacac
    11701 ttgactcaac aaaaagcgct gatggcttaa cgtctttcaa tttttcgatc aatgatgaaa
    11761 tttgatccgg agttccttct tcttcagtgt tgatttccca gatgtaggct gatgggacac
    11821 cgtaagcttt tgagaagtat ttgaagcagc cttcacttgt gacgattagc tttttattgt
    11881 cagcaatagc atcaaatttt gattttgctt ccttatcaag cttctctagc ttctcaacgt
    11941 aagcttttag gttgttttca taggtttcct tgtttttagg gtctttagcg atcaattgct
    12001 ttgcaatatt ttttgaatag ataaccccat tttcaagatt caaccaagca tgagggtctt
    12061 ccttgccttt ttcactttca ccttctaggt aaatcacatc aataccatca gatacagcga
    12121 agtagtcctt gtccttttcc ttcttagcat tttttacaag ctttgtaaac caagcctgtc
    12181 cgccgtcttc aaggttaata ccgttataga gaataagatc ggcattgctg gtcttctcaa
    12241 cgtcttctgg caatggctca tactcatgcg gatcttgacc aatcggcaca atgctgtgca
    12301 agtcaatctt gtcacctgca atatttttag tcatgtcagc aataatggaa ttggtaacca
    12361 caaccttgag cttgtcactc ttagcttcct tgtttccacc attagagcag gcaaccagca
    12421 tgaaaacagc caaaaaagca ctcaaggcga ggctaagttt ctttttcatc agttatctcc
    12481 ttaggatcta ttatttaatt aattaagtat agttaattat gctattagca taactttttt
    12541 ttaggccttt gtcaagattt ttatgaaata atctgatata ataatcatta taaataagag
    12601 aaaggctttt agacatgacg cctaataaag aagactattt gaaatgtatt tatgaaatcg
    12661 gagagcaaaa cattaaaatt tctaacaaaa tggttgcaga gagaatgaag gtttctgcac
    12721 ccgctgtgtc agaaatgatt aagaaaatga tcgcacaagg ctggattgta aaggataaga
    12781 cctgcggcta ttatctaaca gagcaagggc agcgcttagt ggcaaatctt tatcgtaagc
    12841 accgattgat ggaggttttc ttgatccatc aactgggcta tactgctaga gaggtgcacc
    12901 aagaggctga ggtactagag catactgtgt cagatatgtt tattgatcgc ttggataaaa
    12961 cccttggcta tcctactttt tgccctcatg gagggacaat tccacgccgc cagcagccac
    13021 taatcgaaat caacaaaaca acgcttaata ctattaaaga gctgggaatt tttcgtttga
    13081 gcagggtgca tgatcacttt gagcttatcc agtacctaga agcacaccag ctgacgatca
    13141 atagtgagtt tagactgatt caaatagatg acttcgcaaa aacctatacc atcacttatg
    13201 cagataagga attgatcatt cctgaaaaca tcgccaagca gctctttgtt actgctattt
    13261 aaataaaaaa agacctgata tttgctgtca ccacaggcta tcaggttttt ttggtcatca
    13321 ttttttatca ggtaaggcct ctaaaaaggc tatcaagacc ttggctgatt tttttccagc
    13381 ctcaacaata aactgatcga aggtcatatt agcatcgtgg gccgctgtgt cactcatcgc
    13441 cctaacaaca ataaatggct tgccagcagc ttgagctgcc tgtgccactg ctgctccctc
    13501 catttccact gctaaggtct ctgggaaatg tgctttgatg gtatcaatac tgtcttggcc
    13561 ggcaataaag ctatctcctg ttgcaatcag gccaatccga ctattggtct tttcctgatc
    13621 aagcacctgc ttaaaggtct caaccagctt gctatcactg tcaaagtaaa ggggctgcgc
    13681 agccatttga ccatagtcat agccaaaggc cgtcacgtcc acatcatgat acaccaagcg
    13741 atcagcaaca acaacatcac caatagccaa gccactagct attgctccag ccgatcctgt
    13801 atttataata gcgtcagcct gaaaatgctc tgctagcatc gcaactgtca tcgctgacat
    13861 gacctttcca acaccagatt ggactaagac gagctcatgg cgaccaagac gacctgtata
    13921 gtaggtattg gaaagcacct gatgctcttg actatcgtgg agctgctcca ataaaaaccg
    13981 cagctcctct tccatagccg caataattcc aattttcata tgatatcctt atttgttttt
    14041 ttctataaat taaagaccgc ataaaccaag agagcaatca agacaagcac cgctaagaga
    14101 atcagattta accgcgattg aaagcgactg cgctttgcat tttcaattct gcgacttttg
    14161 taaatacgat cagtatgctt atcctcaaag gtcatgattt tggtttcaaa atctgcataa
    14221 tcgtcaggct caaactgttc tccgcgctga gccttttcga taatgtcatc agtcagcaag
    14281 ggcttgccca ttacacatca cctccaaaat gaagggcgta atattgcagg gcaatgatgg
    14341 ttttagcatc gacaagcttt ccttgtgcca ctagatccat acattcttga tagctcagct
    14401 caagaagctc aatcacctca tctgcgtcct gtggtctagg attggcaact ctctgcaggt
    14461 ctgtcgccaa gtacagctta attttttcat tacaaaaacc aatcgctgta taaaactcgt
    14521 gaataagacg caaatcacca gaataggcgg tttcttcctc cagctctcgt gctgctgctt
    14581 ctaatgctga gttggcctca ccgacctcta gttttccagc aggaatttca taagaaatcg
    14641 cttcgatagc cttacggtac tgcttgacaa ttaacagctt acgctctggc gttacagcca
    14701 atatagcgac tgcaccgcga tgaaaaatca attcgcgctt agcctgacct aggccgtttg
    14761 gcaattggac atcatctacc gcaactttga aaatgtgacc atcaaaaatc tcttgccttt
    14821 taatcgtttt ttcttcaaaa tccatgtctg atctccttgc tttctctcca tcattttact
    14881 ttgcttgatt tgggtgatgt ggcagcctct tggcatagcc ctccttcacc acctgacggc
    14941 tgcgccctat agccacactg tctgccggca ctgactgggc tatcgtagac cctgcggctg
    15001 ttaaagcatt ctccccaacc tctactggag ctatcaaagt cgaatgactc ccaataaaag
    15061 cgtgatcgcc aatcactgtc tggtatttcc gttgaccatc ataattaacc gtaatgcttc
    15121 ctgcaccaat attaacctct gagccaatct cggcattccc caggtaagtc aaatgccctg
    15181 ccttggtatt ggcccctaga tgagacccct taacctctac aaagttccca atatgaacgc
    15241 tctcatcgag ctgggagtct gggcgaatgt gcgcataggg ccctactgtc acaccatctg
    15301 ctaggactga atcctcaatc actgactggc tcaccactac gccctcacca agcctcgaa
//
LOCUS       DARYNN010000048        15055 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.048, whole genome shotgun sequence.
ACCESSION   DARYNN010000048 DARYNN010000000
VERSION     DARYNN010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15055)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15055)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15055
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.048"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(419..2830)
                     /locus_tag="TVB59_001570"
     CDS             complement(419..2830)
                     /locus_tag="TVB59_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEL1010442.1"
                     /translation="MKKKHIVLGSAVAILLATNAASYQFGMHKALNSSSKDNSIAYID
                     SKDGKKALPKEKTMDQISAEEGISAEQIVVKITDQGYVTSHGDHFHFYNGKVPYDAIL
                     SEELLMTDPNYQFKQSDVVNEILDGYIIKVDGKYYVYLKPGSKRKNIRTKQQIAEQVE
                     KGTKEAKEKGLAKVAHLSKAEVAAVNEARSQGRYTTDDGYIFSPTDVIGDMGDAFLVP
                     HGSHFHYIPKKDLSPSELVAAQAYWNNKQGGKPSVIGGQPLPGQGDQPRPYDIPVNPI
                     HHPAGNLPSVGDPSLSFADKTFGELLDQLHGLDKKYRHVEEDGLIFEPTQVTLANAFG
                     YVIPHGDHYHIIPREQLSALEITLADRYLAGQTQGSPIAKPKPATQDQTAKEVTHQFL
                     GHQIKAYGKGLDGKPYDTSDHYVFSKASISSVDKAGITAKHEEHFHYMGFGELEQEEL
                     DQVAQWLQEHGQADEIARALVQSDGKDMSFDAKHVSRKVTNGGKVGYMMTKDGKEYFY
                     DREHLDLTQIAFAEQELMLKDKQHYIYDIVDTGVQPKLAVEVSSLPMHAGNATYDTWT
                     SFVIPHIDHIHVVPYSWLTKDQIATIKYVMQHPNTRPDVWSNPNHDEAGGVIANVTPA
                     DQRTSMENWQIIHSAEEVQAAIKAGRYAAPDGYIFDPKDVLAEGTFVWRNDSFSIPRV
                     GGRSLRTITKDELSHDEWQKVQELLGNKTSDAAESTIKPTKDQEPSAQDTAADGIEQT
                     KSLFDDIPNYGLDRATLERQINQLAEIAGIKPEYLIFVPEGVKFYDQKGHLMLYDVTT
                     LQQIK"
     gene            complement(2845..3768)
                     /locus_tag="TVB59_001571"
     CDS             complement(2845..3768)
                     /locus_tag="TVB59_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000755138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HEL1010443.1"
                     /translation="MKRKWIHLTLLLALFSGLVACSKPKEQSKQSRGMTIVTSFYPIY
                     AMTKAVSGELNDVRMIQSGAGIHSFEPSVNDVAAIYDADLFVYHSHTLEAWADDLDPN
                     LKKSKVAVFEASKSLTLDRVTGLEDIEVTDGIDPATLYDPHTWTDPILAGEEALAIAK
                     ELSRLDPKHEAIYTENAQAFQKEAKELADEYTKKFKKTSSKTFVTQHTAFSYLAKRFG
                     LKQLGISGISPEQEPTPRQLTEIQDFVKEYKVKTIFAEDNVNPKIAKAIAKTAGAKVK
                     LLSPLEAAPKNNKSYLDNLRANLEALYQSLK"
     gene            complement(4095..5642)
                     /locus_tag="TVB59_001572"
     CDS             complement(4095..5642)
                     /locus_tag="TVB59_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL1010444.1"
                     /translation="MKKQSLKKVSLLTVTVISSLALAANANTYTTYARDNVVTATSQA
                     AEGFDFVATILDSNGRALEGKTVVLLDTTANPAKQVASAVSNSNGQAIFTQLPLNINL
                     SVSVDGETKGYTVRTSLAGSKEAASFVAKGAGTKEPLYSKNVIDITVRNQDSEPLEGQ
                     TVTLKIRQGQLVGSLVSDKNGKVTFKDRLLDGTFYHYELNGKYIGQVMTKMSVNAYLD
                     TSSSSSSGTSPQSKDTPKQEDGKSSPLEEGFHFVVTALDKEDRVVAGKEVSLTALIDG
                     AKTTIASAKTNADGQAVFTKLPLSRNISVSIDGKLQGYTVRTSESNEHKAAAFYVDGK
                     GTKPVVYSKTPAIVTVYDANGNKLAGQEVVLKNRYGAIRAIGKTDQSGKATFVNQLMD
                     GMFYEIVINGVKIPKKASTGSDVSGFLTKAQIRTDNKLSESERHSKDTKPLGKEPKDP
                     EKDKNVAKPETKSSSNRNVAPKEGKKETKALPRSGESAAPMVAFMGVLLIGLAAVIGL
                     VTKRRSS"
     gene            complement(6267..7148)
                     /locus_tag="TVB59_001573"
     CDS             complement(6267..7148)
                     /locus_tag="TVB59_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEL1010445.1"
                     /translation="MKKALLIVNPSSGGEKAKEYEALAYDKLASYFDDVDVKHTEKGG
                     DAKRFAHEAAQQRLDSVFVMGGDGTVNEGISGLAEQDYRPKFGFFPLGTVNDLARALG
                     MSLDPEEAINQISFETTSPLDIGKVNDAYFMNVVAIGTLPEAINDVAPEEKTTFGKMA
                     YFMSGFKQLIKNKSYTFQLDIDGKTKEINSTTLLIGLTNSIGGFERILPEARVDDGLL
                     HLIYLKDSNLLETVKALPSLLKGVEASDQTLGYQTFKEATIAMKEGQLSINVDGDEGE
                     ALPITVKVLPQHLQVYR"
     gene            complement(7313..8314)
                     /locus_tag="TVB59_001574"
     CDS             complement(7313..8314)
                     /locus_tag="TVB59_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1010446.1"
                     /translation="MVTLKDIAALAKVSPATVSRVLNKDQSLSVGQETKHRILTIADE
                     LGYQKHLKATNSPKSKLKIAIVQWYSQEEELNDLYYYAIRIGIEKRAYELDYDIVRYF
                     NNDILRVSDDHAGIIAIGKFSACQIKELEALSQHLVFVDSDTLELGHPCVTTDFDNAV
                     LKVLDYFMSKGIYSIGMIAGEEKTTDGREALVDQRFRTYKNYASEHGIYQPRYVYIGP
                     FSAQSGYELMTQAIEELGDDLPKAFFIANDTLAIGALRALQERGLAVPERVELISFND
                     TPLTRQVFPALSSVTVFTEDMGRMAVDVLNRNILNPERVKTMTILATELTLRDSTIG"
     gene            8455..9627
                     /locus_tag="TVB59_001575"
     CDS             8455..9627
                     /locus_tag="TVB59_001575"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEL1010447.1"
                     /translation="MDIAQLKQSFTDVFGKEPDAVFFSPGRINLIGEHTDYNGGHVFP
                     AAISLGTYGLARKREDQQLRFFSANFEEAGIIEVDLNQLTFDQADLWANYPKGVLSFL
                     QKAGHLIDTGFELYVFGNIPNGSGLSSSASLELLTGIVAQELFGLDVERLDLIKIGQQ
                     AENHFIGVNSGIMDQFAIGMGADKQALYLDTNTLAYEAVPLDLGDHVIVIMNTNKRRE
                     LADSKYNERRAECEQALEELNALLDIKALGELDAQRFDEYSYLIKDGKRLKRARHAVL
                     ENQRTLQARQALEAGALEQFGRLMNASHVSLEHDYEVTGPELDTLVHTAWEQEGVLGA
                     RMTGAGFGGCGIAIVAKDKVDSFIETVGKAYTKVIGYAPAFYLAEIAQGARLLSRK"
     gene            9631..11115
                     /gene="galT"
                     /locus_tag="TVB59_001576"
     CDS             9631..11115
                     /gene="galT"
                     /locus_tag="TVB59_001576"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEL1010448.1"
                     /translation="MASLIDTFVRKVIEHSDYTSEDAIYIRNRVLALVGENHVWQETS
                     LTALIALKEALVELAAENGKIGRLPEEKDCLGAELMNMITPIPSVVNRRFWDTYAQSP
                     QQAISDFYQLSQLNDYIKTAAIAKNISFTVPSQYGDMAITINLSKPEKDPKAIAAAKK
                     AKASSYPKCQLCMENEGYQGRINHPARANHRIIRMSLGNEAWGFQYSPYAYFNEHSII
                     FNTEHVPMTISTSTFRQLLDIVDILPDYFVGSNADLPIVGGSILTHNHYQAGRHVFPM
                     EIAKQDKRFTFKGFPDIQAATLNWPMSVIRLRSSNKDQLVQLADTIRLAWRHYSDDSV
                     DIVAYTNQEPHHTITPIARKKEGQFELDLVLRDNHTSEQFPDGVYHPHADVQHIKKEN
                     IGLIEVMGLAILPPRLKEELVEVKKYILNQANQIADYHKDWADQITLRPDLSAITVDD
                     IIQEEVGSVFVRVLEDAGVYKRDQEGQAAFMRFLKSIGIEAIEE"
     gene            11125..12135
                     /gene="galE"
                     /locus_tag="TVB59_001577"
     CDS             11125..12135
                     /gene="galE"
                     /locus_tag="TVB59_001577"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEL1010449.1"
                     /translation="MTVLVLGGAGYIGSHTVDWLISQREEKVIVVDSLVTGHRKAVHP
                     EALFYKGDLADKAFMRQVFRDNPDIDTVIHFAASSLVAESMADPLKYFDNNTAGMIKL
                     LEVMREAKVKRIVFSSTAAVYGIPKTVPILESAPKCPINPYGQSKLMMETIMTWADKA
                     YGITFVALRYFNVAGAKPDGSIGEDHEPETHLLPIILQTAQGVREQVMIFGDDYDTPD
                     GTNVRDYVHPIDLADAHILAMAYLRQGKPSQVFNLGSQTGFSNRQLLEAARRVTGQAI
                     PAKKAARRPGDPDTLIASSEKARKVLNWKPSYDDIDKIIASAWAWHTKHPKGYDDKAS
                     GS"
     gene            12212..13255
                     /locus_tag="TVB59_001578"
     CDS             12212..13255
                     /locus_tag="TVB59_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEL1010450.1"
                     /translation="MNIYQDIIEYIDQVPVTQLRLINTNGVEAHLLTLGATLQAFLVS
                     NEKQPKNIILGHDRPSDYLKNPLCAGQTIGRVAGRIKRGSFQLEQQRVCVDTNENGHC
                     LHGGFKGFHKLHWPYDTRQTVDYLEVTFKRDILEADDHFPGDLTVSITYRLDNHNRLS
                     IHFKAHSMRGTSLFNPTNHVYFNLGQTQDLTNHNLYIAASHRIETDNELIPTGQKLAV
                     DQTVYDFRSIKSLYPAIVENNGFDTAFEIDQQAIGTTKPIAVLQDSVSHDQISIYSDR
                     NALVIYTMDSIQDGLYFGRDQGKEGLAREGIAMEAQTLPDAIHHNQFGDIILKEGGTK
                     SYTICLAYEHLPD"
     gene            13556..13699
                     /locus_tag="TVB59_001579"
     CDS             13556..13699
                     /locus_tag="TVB59_001579"
                     /inference="COORDINATES: protein motif:HMM:NF013921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL1010451.1"
                     /translation="MIFDKDTNLKHKHRHQKFWYMGYYGDTAGKNLKTIAKYISNHYR
                     KIG"
     gene            14313..14474
                     /locus_tag="TVB59_001580"
     CDS             14313..14474
                     /locus_tag="TVB59_001580"
                     /inference="COORDINATES: protein motif:HMM:NF013753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL1010452.1"
                     /translation="MPYSNAKLEPTNKTIKDMKEQAFGFRNFKNFKVKIPNALNITKE
                     ETKFISSRA"
BASE COUNT         4341 a         3394 c         3011 g         4309 t
ORIGIN      
        1 aattgtacgg ctgctaacct ttttcctaac ccttttagac accaaaaaac tccccttatc
       61 gtttttagtg attgtttttc actgtccact ttaaagggga ggtctagcta ttaaaggcta
      121 ggcggttttg actggaggac tattaggtgt gaggttaatt ggtaaaaact ctttctgtgc
      181 tgccctcctt aggtcatata gactttcttg gaaccaaaac ccacatatag cctacagaga
      241 tccaatgctt taaaagctat gaggtgctaa gctgctgatc aagtcagctt ctctgactgt
      301 tgctgcaagc aaaagcctac taagcgatct taggctgtga ggcgtaagaa caggtcatca
      361 taccaatagc tttttgggga taagctgtga tttgtatgcc ttagctattt tatagtgttt
      421 atttgatttg ttgcaatgtt gtcacatcat aaagcattag gtgtcctttt tggtcataga
      481 atttgacacc ctctggcacg aaaataagat actccggttt aatgcctgct atttcagcta
      541 actgattgat ctgacgttca agagttgccc gatctaaacc ataattagga atatcgtcaa
      601 ataaagactt ggtctgctct atgccatctg cggcagtatc ttgcgctgac ggttcctggt
      661 ctttggttgg cttaatagtg ctttcagctg cgtctgaggt cttattgcct aataattctt
      721 gaaccttttg ccattcatca tgagataact catctttagt aatggttctt aaagagcgtc
      781 caccaactct aggaatgcta aaggaatcat tacgccaaac aaaggttcct tcagcaagaa
      841 cgtccttagg atcaaaaata tagccatctg gagctgcgta ccgacctgcc ttgatagctg
      901 cttggacctc ttcggcagag tgaataattt gccagttttc cattgaagta cgttgatcag
      961 ctggtgtgac attagcaatg actcctccag cttcatcatg atttgggtta gaccaaacat
     1021 caggacgagt attagggtgc tgcatgacat atttgatggt cgcaatctga tccttagtta
     1081 gccatgaata aggtacaaca tggatatgat cgatgtgagg aatgacaaaa gatgtccatg
     1141 tatcataggt tgcattacca gcatgcatcg gtaggctgga tacctctaca gctagctttg
     1201 gctgaacgcc tgtatcaaca atgtcataaa tatagtgttg cttatcctta agcatgagct
     1261 cttgctctgc aaaggcaatt tgtgttaggt ctaaatgctc acgatcatag aaatactctt
     1321 tgccatcttt tgtcatcatg taaccaacct taccgccatt ggttaccttg cgactgacat
     1381 gcttagcgtc aaaggacatg tctttaccgt ctgattgaac taatgccctt gcaatctcat
     1441 ctgcttgacc atgctcctgc agccattgtg caacctggtc aagctcctct tgctctagct
     1501 caccaaagcc catgtaatgg aaatgctcct catgcttagc tgtgatgcct gccttatcaa
     1561 cagaggaaat agatgcctta ctaaagacat aatgatcact cgtgtcataa ggcttgccat
     1621 ctaagccttt accataagcc ttaatctgat ggccaaggaa ttgatgtgta acctcttttg
     1681 cagtctggtc ttgagtagct ggctttggct tagctattgg actgccctgc gtttgacctg
     1741 ctaggtaacg atcagccaag gttatttcaa gggctgacaa ttgctcacga ggaataatat
     1801 ggtagtgatc tccatgagga ataacatagc caaaggcatt ggcaagggtc acctgagttg
     1861 gctcaaaaat gagaccatct tcctcgacgt gcctgtattt cttatccaag ccatgcaatt
     1921 gatccaacaa ttctccaaag gttttatctg caaatgatag gcttggatct cctactgacg
     1981 gcaaattccc agctgggtgg tgaatcgggt taacaggaat atcatatggt ctaggctgat
     2041 ctccttgacc tggtaaaggc tgaccgccaa taacacttgg ttttccgcct tgcttgttat
     2101 tccaataggc ctgcgctgct actagctcac ttggggataa gtccttttta ggaatatagt
     2161 ggaagtgact gccatggggc actaaaaagg catctcccat gtctccaata acatctgtcg
     2221 ggctaaagat atagccatca tcagttgtat agcgtccttg acttcttgct tcgttaacag
     2281 ctgccacctc tgccttactc aagtgggcaa ccttagccaa gcctttttcc ttagcttcct
     2341 ttgttccctt ttcaacctgc tcagcaattt gctgcttggt acgaatattt ttacgcttgc
     2401 ttcctggctt tagataaaca taatacttgc catcaacctt gataatatag ccatctagaa
     2461 tctcgttaac aacatcagac tgtttaaact gataattggg gtccgtcatt aatagctctt
     2521 cactaagaat agcatcatag ggaaccttac cattgtagaa atggaaatga tcaccatgtg
     2581 aggttacata gccttgatct gtgattttaa caacgatttg ctctgcagag atcccctctt
     2641 ctgcgctgat ttgatccatt gttttttctt tggggagggc ttttttgcca tcctttgaat
     2701 caatataggc aatgctatta tctttagatg aggaatttag agccttatgc attccaaact
     2761 gatatgaagc agcattagta gccaataaaa tggccacagc tgatcctaaa acaatatgct
     2821 tctttttcac gttttcatct ccctttattt taagctttgg taaagagctt ccaaattagc
     2881 tctcaaattg tctagatagg acttgttgtt tttgggcgct gcctctagtg gactgagcag
     2941 cttgaccttt gctcctgctg ttttagctat cgccttagca attttaggat taacattatc
     3001 ctctgcaaaa atcgttttta ccttatattc tttaacaaag tcttgaattt cagttagttg
     3061 gcgaggagta ggctcttgct ctggcgaaat accagaaata cctaactgct ttaagccaaa
     3121 gcgttttgct agataagaaa aggctgtgtg ctgtgtgaca aaggttttag atgatgtctt
     3181 tttaaacttt ttagtgtact catcagccag ctcttttgct tccttttgga atgcttgagc
     3241 attctcagtg taaatggcct catgcttagg atctaaacga ctgagctcct tagcaatagc
     3301 gagtgcttct tcacctgcta aaataggatc tgtccaggta tgaggatcat acagggtagc
     3361 agggtcaatg ccatctgtca cctcaatatc ctccaaacca gtaacacgat ctaaggttaa
     3421 agatttggaa gcttcaaaaa cagcaacctt tgatttcttc aaattaggat ccaaatcatc
     3481 agcccaggcc tctagggtgt gagagtgata aacaaataaa tcagcatcgt aaatggcagc
     3541 aacgtcattt acagatggct caaaggaatg aatacctgcc cctgactgaa tcatccgaac
     3601 atcgtttagc tcaccagata ccgcctttgt catggcgtaa ataggataaa agctagtgac
     3661 gatcgtcatg cctcttgact gcttgctttg ctccttgggc ttgctacagg caacaagacc
     3721 tgaaaaaaga gcaagcaaca gtgttaaatg tatccatttt cttttcatat aatctccttt
     3781 gctcattaac cagttatgaa ccggttaatt ttaacagctt tagatgtatt tgtcaaattt
     3841 tttaataaaa aataaaagcc attaaaacga tggcttaatc agcccctaac ctgcttaacc
     3901 tttataagaa gccatagctc tatgataaac tgtggtctgt gacgcatgac ctcactgtct
     3961 gttatcttac tgttgcatga tacgtttaaa aaagatttag ccttcttttt ttagattgta
     4021 gaacggcgct gaacaatcac ttaaccgtca aaaaaacgcc ttgatagctg caagacgttt
     4081 ttacttattt ggttttagct agagcgacgt tttgtcacaa gaccgatgac agctgcaagg
     4141 cctattaata gaactcccat gaacgctacc atcggcgctg ctgattcacc agatcttggc
     4201 aaagccttag tctctttttt accttcttta ggggctacat tacggtttga cgaggacttg
     4261 gtttctggct tagcgacatt cttatccttt tcaggatcct ttggctcctt gcctaagggc
     4321 tttgtgtctt tagaatggcg ctcagactcg ctgagtttat tatcggttct gatttgagct
     4381 ttggttaaaa agccgctgac atcactaccg gtagaggctt ttttaggtat cttgaccccg
     4441 ttgataacaa tctcataaaa cataccgtcc atgagctgat tcacaaaggt tgccttacct
     4501 gattgatcag ttttgcctat tgccctgata gctccgtatc gatttttcag cacaacctct
     4561 tgccctgcca acttatttcc attggcatca taaacagtta ctatggctgg tgtcttagag
     4621 taaacaacag gctttgttcc tttaccgtcg acataaaaag cagcagcctt atgctcatta
     4681 gactcactcg tgcgaacagt atagccctgt agcttaccat caattgagac actgatatta
     4741 cgtgatagtg gtagtttggt aaagactgct tgaccatcag catttgtctt tgctgaagca
     4801 attgtcgtct tagcaccgtc tatcagagca gtcaagctta cctccttgcc tgcaacaacc
     4861 ctatcctctt tatctagggc agtgacaaca aaatgaaagc cttcctctag cggacttgac
     4921 tttccatcct cctgcttagg agtgtccttg gactgaggtg acgtacctga tgacgagctt
     4981 gatgaggtat caaggtaagc attaacagac atttttgtca tgacctgccc tatatactta
     5041 ccattaagct cataatgata aaaggttccg tccaacaaac gatccttgaa ggttaccttt
     5101 ccatttttat ctgagacaag acttcccacc agttgaccct gacgtatttt tagggtgact
     5161 gtttgccctt ctaagggctc actatcttga tttcggaccg taatatcaat gacattttta
     5221 ctataaagag gctcctttgt ccctgctccc ttagcgacaa agcttgctgc ctctttagat
     5281 ccagcaagac tggttctcac tgtatagccc ttggtttccc cgtcaacaga aacactcaaa
     5341 ttaatgttta agggtaattg agtaaaaata gcctgaccat tgctgttaga gacagcagaa
     5401 gctacctgct tagcgggatt agctgtcgtg tctaacaaga caactgtttt tccttcaaga
     5461 gcacgaccgt tgctatcaag tatcgtggca acaaaatcaa aaccctcagc cgcttgcgac
     5521 gtcgcagtga caacgttgtc tctggcataa gtcgtatagg tattggcatt ggctgccaag
     5581 gccaagctag atataacagt aaccgttaaa agactgactt ttttcaatga ctgtttcttc
     5641 ataaaaaagc tcctttattt tgattaacta gcctagtttt aatgggaaat atccccttga
     5701 taccctttct gaggtgatag gaacagcagc aatctctctt agcctatgat gcctaagctt
     5761 taaagctaag ttttcaaagt ccacctaagg ggctacatgc cacaacaaaa agcatcagat
     5821 gaacagacat ctagaggcaa cagccgatct aagataatag ttagtagcca ttttagctac
     5881 tctcaaggct gtcgccgcag tgatgatgtg attgtctatg ctttttaata aaacttaact
     5941 agttaagatt tttgtgctgc tatcctatca aataaccccc gccaagtcaa caacaatgct
     6001 cataccacag caagcaaagc attttgatga tgactgaaca gccaaatcag ccaagcccca
     6061 ggcagcaaaa aagaggattc aaaccaaatc ctctctctac taagcctgct gctgttaacg
     6121 tatcatgcta aaggcaaatg gtatagccac gctgatatga aggtctgatt aacagctacg
     6181 acggacacgc ttgttaaggc taccattgct aatcacacta ggtcatatcc tccaccgtat
     6241 aagaatgact aacttcatta ttcagattaa cgatatacct gcaggtgctg aggaagtacc
     6301 ttgacagtga ttggtaaggc ctcaccctca tcaccgtcca cattgataga tagctgtcct
     6361 tccttcatgg caatagtggc ctccttgaag gtttgatagc caagtgtttg atctgaagcc
     6421 tcaactccct tcaataggct aggaagggcc ttcaccgttt ctaatagatt gctatccttc
     6481 agatagataa ggtgcagcaa accatcgtcc acacgtgcct ctggcaaaat ccgctcaaag
     6541 cccccgattg aattggtcaa gccaatcaag agtgttgtgc tgttgatttc ttttgttttg
     6601 ccatcaatat ctagctggaa ggtatagctt ttatttttga tcagctgctt aaagcctgac
     6661 ataaaataag ccattttccc aaaggtcgtc ttctcctcag gggcaacatc attgatcgcc
     6721 tctgggagcg tccctatggc aacaacattc ataaagtaag catcgttgac cttaccaata
     6781 tccagaggac tggttgtctc aaagcttatc tgattaatcg cttcctctgg gtctaacgac
     6841 atgcccaagg cacgtgccaa atcattgact gttcctagag gaaaaaagcc aaacttaggg
     6901 cgatagtcct gctctgcaag cccgctgatc ccttcattga ctgttccatc acctcccatg
     6961 acaaagacac tgtccagccg ctgctgggct gcctcatgag caaaccgttt ggcatctcct
     7021 cctttttcag tgtgcttaac gtcaacatca tcaaaatacg aagctagttt atcataggct
     7081 aaggcttcat attccttggc tttctcacca cctgagctag ggttaacaat caatagggct
     7141 tttttcattt atgatatcct acattttcta ttatatttca cgactattat aatcattatt
     7201 caaaacatcg tcaaataata ctcactatgt cattagtcag tcttaaagct tctaatatgg
     7261 ttgccgtcta gtgtttcatt ttactgaact ctttacccag ctagctcaat gcctaaccaa
     7321 tcgtgctgtc tcttaaggtc aactctgtcg ccaatatcgt catggtcttg acacgttctg
     7381 ggttaaggat attcctatta agcacatcaa cagccatacg tcccatatcc tctgtaaata
     7441 cagtcacact agaaagcgca ggaaagacct gtcttgttaa aggagtatcg ttaaaggaga
     7501 taagctcaac acgctcaggc accgcaagcc ctctttcttg gagagctctt agagcaccta
     7561 ttgcaagggt atcattagca ataaaaaatg ctttaggcaa atcatcacct agctcctcaa
     7621 ttgcctgtgt cataagctca tagccagatt gtgctgaaaa aggaccgata tagacatacc
     7681 tcggctgata aatcccatgc tcagaggcat aatttttata ggtgcgaaag cgctggtcca
     7741 ctaaagcttc tctaccgtca gttgtctttt cctcaccagc aatcatgcca atgctataaa
     7801 tccctttgct cataaaataa tcaagaactt tcagcactgc attgtcaaag tcagttgtga
     7861 cacaggggtg gcccaattca agcgtgtcac tatcaacaaa caccaaatgc tgggataagg
     7921 cttcaagctc cttgatttga caagcgctaa actttccaat agcaataatc ccggcatggt
     7981 catctgaaac cctcaaaatg tcattgttga aataacgaac aatatcataa tccaattcat
     8041 aagctctttt ttcaatgcca atgcggatcg cataatagta gaggtcattg agctcctctt
     8101 cttgagaata ccattgaaca atagctattt ttagctttga tttagggcta ttcgtcgctt
     8161 ttaaatgctt ttggtagccc agctcatcag caattgtgag aatgcggtgc tttgtctctt
     8221 gaccaacaga caagctttgg tccttattta aaactctaga aacagttgca ggagaaacct
     8281 ttgccagagc tgcaatatcc ttaagcgtta ccatatcaaa ccttctttct gatttcttct
     8341 agtatatcac aagcattttc aaaagcaata tttagtaaaa ttttagtaaa aatgttgacg
     8401 agcagcttag cgaagcgtaa aatcaagcta tcaacatcgt taaaggagcc gctaatggat
     8461 atcgcgcaac ttaagcaaag ctttactgac gtttttggca aggagccaga tgctgtcttt
     8521 ttctcaccgg gtcgcatcaa cctcattggt gagcacactg attacaatgg tggacatgtc
     8581 tttccagctg ctatcagtct gggaacctat gggctggccc gcaagcgtga ggatcagcag
     8641 ctgcgctttt tctcagcaaa ttttgaagag gctgggatta ttgaggttga cttaaatcag
     8701 ctgacctttg atcaggctga cctttgggct aattacccta agggagttct ctcctttttg
     8761 caaaaagctg ggcaccttat tgatacgggc tttgagcttt acgtttttgg caacattcca
     8821 aatgggtctg gtctgtcctc ctcggcatca ctggagcttt tgacaggtat tgtggcacaa
     8881 gagctgtttg ggcttgatgt ggaacggtta gatctgatta aaatcggtca gcaagctgaa
     8941 aatcacttta tcggggtgaa ttcaggtatc atggaccaat ttgccatagg catgggagct
     9001 gataagcagg ctctatacct tgataccaac accttagcct atgaggctgt tccgcttgac
     9061 cttggtgatc acgtgattgt catcatgaat accaacaagc gccgagagct agccgattca
     9121 aagtataatg aacgccgagc agagtgtgaa caagcccttg aggaattaaa tgcccttctg
     9181 gatattaaag cactggggga attagacgct cagcgctttg atgagtacag ctaccttatc
     9241 aaagatggta aacgtctcaa acgcgctcgc cacgctgttt tggaaaatca acgaacactc
     9301 caagcaagac aggcccttga agcaggagca ttggagcaat ttggtcgtct gatgaatgct
     9361 tctcatgtat ccttggagca tgattatgag gtcacaggcc ctgagctgga cacactggtc
     9421 cacaccgctt gggagcaaga aggggtccta ggggctcgca tgacaggagc aggctttgga
     9481 ggctgtggca ttgctatcgt ggctaaggat aaggtagata gctttatcga aacagttggc
     9541 aaggcctata ctaaggtcat tggctatgct ccagcctttt atctggctga gattgctcag
     9601 ggagcacgac tactttcaag gaaataagat atggcaagct taatagacac ctttgtaagg
     9661 aaggtgattg aacacagcga ctacacatca gaggacgcta tttatatccg caatcgggtt
     9721 ttagcattgg ttggtgagaa ccatgtctgg caagaaacct ccttaacagc cttaatagct
     9781 ctcaaagaag cattggttga gctagctgct gaaaatggca aaataggcag gcttcctgaa
     9841 gaaaaggact gcttaggagc tgaattaatg aacatgataa cccctattcc aagtgtggtt
     9901 aatcgtcgct tctgggatac ctatgcacaa tctcctcaac aggctatctc agatttttac
     9961 cagcttagtc agctaaatga ctacatcaaa acagcagcaa ttgccaaaaa catctccttt
    10021 acagtgcctt ctcaatatgg tgatatggct attaccatta acctatcaaa gcctgaaaag
    10081 gaccctaagg ccattgcagc cgctaagaag gctaaggcat cctcttatcc aaaatgccag
    10141 ctttgtatgg aaaacgaagg ttatcaagga cggattaacc acccagcccg agctaatcat
    10201 cgcattatcc gtatgagctt aggcaatgag gcttggggat tccagtattc accctacgct
    10261 tattttaatg agcacagtat tatttttaat actgagcatg tgccaatgac aatcagtaca
    10321 agcaccttta gacagctcct tgatattgtt gatatcctgc cagactattt tgtcggctct
    10381 aatgctgatc tgcctattgt tggcggctct attttgaccc acaaccatta tcaggccggt
    10441 cggcacgttt ttccgatgga aatcgcaaaa caagacaaac gctttacctt taaaggattt
    10501 ccagacatac aggctgccac tctcaactgg cctatgtcag ttatccgact gcgcagcagc
    10561 aacaaagatc agctagttca attagcagac acgattcgac tggcttggcg tcattattct
    10621 gacgacagtg ttgatatcgt cgcttatacc aaccaagagc ctcaccatac catcacacct
    10681 attgccagaa aaaaagaagg gcagtttgaa ttagacttgg ttctacgtga taaccatacc
    10741 tctgagcaat ttccagacgg tgtttaccac ccacatgccg atgtgcaaca cattaagaaa
    10801 gaaaacatcg gccttattga ggttatgggg ctagctattt taccaccgcg cctcaaagag
    10861 gaattggttg aggtcaaaaa atatatcctc aatcaagcca atcaaatcgc agactaccac
    10921 aaggactggg ctgatcagat cacattacga ccagatctct cagcgataac tgttgatgac
    10981 attatccaag aagaggtcgg ctctgtcttt gttcgtgtcc ttgaggacgc tggcgtctac
    11041 aaacgtgatc aagaaggtca agcagccttt atgcgttttc ttaagagcat tggcattgaa
    11101 gcaattgaag aataggagga aaaaatgact gttctagttt taggcggtgc aggctacatt
    11161 ggatcacata cagtggactg gctaatatca cagagagaag aaaaagtcat tgttgttgat
    11221 agcttggtga cagggcaccg taaagccgtt cacccagagg ctctgtttta caaaggagac
    11281 ttagcagaca aagcctttat gcgtcaagtc tttagggaca atccagacat agacactgtg
    11341 attcactttg ctgcctcttc cttggtcgca gaatcaatgg cagaccctct gaaatacttt
    11401 gacaataaca cagcaggtat gattaagctg cttgaggtca tgagagaagc caaggttaag
    11461 cgcattgtct tttcatcaac agcagccgtc tatggcattc caaaaacagt ccccatctta
    11521 gagtcagcgc ctaaatgccc aatcaatcct tatggccaaa gcaagcttat gatggaaacg
    11581 ataatgacct gggccgacaa agcctatggc atcacatttg tggcccttcg ctacttcaat
    11641 gttgccggag caaagccaga tggctccatc ggtgaagacc acgagccaga aacacattta
    11701 ttacccatta tcctacagac tgcacaggga gtgcgtgagc aggtgatgat ttttggtgat
    11761 gattatgaca caccagatgg tactaacgtt cgagattacg tccatcctat cgatttagct
    11821 gatgcacaca ttttagcgat ggcatacctg cgtcagggca aaccatcaca ggtctttaat
    11881 ctagggtctc aaacaggctt ttccaatcgt caactgcttg aagccgctcg tcgggtaaca
    11941 ggacaagcca taccagccaa aaaagctgca agacgtcccg gtgatccaga caccttaatt
    12001 gcgtcatcag aaaaagcacg caaggttctc aattggaagc caagctatga cgatattgac
    12061 aagataatcg catcagcctg ggcctggcat accaagcatc caaaaggata tgacgataaa
    12121 gcaagtggca gctagtccct caagacagct accacagcaa gtagtcagcc tcccttaatt
    12181 catacaccta tactaatagg agaaacaaac tgtgaacatt tatcaagaca tcattgaata
    12241 catcgatcaa gtgccagtca cccagctaag actgattaat actaacggtg ttgaggctca
    12301 cctattgaca ctaggagcca ctctacaggc ctttctagtg tcaaatgaaa agcagccaaa
    12361 aaatatcatt ttgggacatg accgaccaag tgactaccta aaaaatcctc tttgtgcagg
    12421 gcaaaccatt ggccgagtag caggtcgcat aaagagagga agctttcagc tagagcagca
    12481 aagggtttgt gttgacacca atgaaaatgg gcattgcctg catggaggct tcaagggctt
    12541 tcataagctt cattggcctt atgatacccg ccaaacagtt gattaccttg aagtaacctt
    12601 taaaagggat attttagaag cagatgacca tttcccaggt gacctgaccg taagcattac
    12661 ctaccgtcta gacaaccata atcgtttaag cattcacttt aaggctcata gcatgagagg
    12721 cactagccta ttcaatccaa ccaaccatgt ttattttaat ttagggcaaa cacaagactt
    12781 aaccaatcac aacctataca tcgcagcatc acataggatt gaaacagata atgagctaat
    12841 cccaacaggt caaaagctag cagttgacca gacggtctat gattttagat caataaagtc
    12901 cctctatcct gctattgtcg aaaataatgg ctttgatact gcctttgaaa ttgatcagca
    12961 ggctattgga acaaccaaac ctattgctgt cttacaagac agcgtcagcc atgaccaaat
    13021 cagcatctac tctgaccgaa acgcactcgt catttatacc atggacagta tccaagatgg
    13081 cttgtatttt ggaagagatc agggcaagga gggactggct cgtgagggga tcgctatgga
    13141 agcacaaacc ctgcctgatg ctattcacca caaccagttt ggtgacatta tcctcaaaga
    13201 aggaggcacc aaaagctaca ctatctgcct agcctatgag catctgccag attaacataa
    13261 gtacagccaa gctttaatga aataacaaga ccttgatttt tttgaattgc accccaaccg
    13321 ttagccaaaa actctaacaa gcgaggatca gttcattcat caaggtcttt tcctcttttt
    13381 atctataggc gttacaaagt agatatagga acatcatacc aaatatgtgg aatgctaaga
    13441 gcttatcatc acaaagcgaa tacatgttcc gactacatct atgcattagt aagtcttttt
    13501 cctaaacgaa gtgttgccag ctttatgaga tacttaaaag tataagagca gcctaatcat
    13561 ttttgacaaa gacaccaacc ttaagcataa acataggcat cagaaatttt ggtatatggg
    13621 ctattatgga gacacagctg gtaaaaatct aaaaacgata gccaaatata tttcaaatca
    13681 ctataggaag atagggtagc aaaccaactg acatcatttg agaccattga tccatttaca
    13741 ggccaaccaa ataagaaaaa gtaacctttt gattgaactc ccgctcggaa aagtggagcg
    13801 cgagtattca atgacctcgt tatcctcgac cgatgagagc agcttatagt cacagtataa
    13861 agaggctgga acagacaacc tcttttgatt gacaataagt gtttgatagc attgtatggg
    13921 attactttca catcattcag cacctgggtc gagctttgat gaccgccaga attgatagcc
    13981 attatgaagg gctttgagca gccatttctg ctttatcgaa ccataaaata tcattgatga
    14041 ctgctccaaa aggacagtca taaactgtct gatcagcgct tctagtcacg aacctttaag
    14101 caaaccttaa tactcaaaaa aggtaagtca gaaaatactt gatttctcag atgagctgtg
    14161 gaattaccac gacctttacc agctcttgct ctttcatttt caaaaagtgg gtaaccgagt
    14221 ttttcgggct gattgaagag ctttaagctt ggtcaatcat cacgttttaa ccgtcctcaa
    14281 aatctttttg aaatacaaac cctacatcac aaatgcctta ttccaatgct aaattggagc
    14341 ccactaacaa gactattaag gacatgaaag agcaagcctt tggatttagg aactttaaga
    14401 acttcaaagt caagattccc aatgctttaa acatcacaaa agaagagaca aaatttatct
    14461 cttctcgtgc ttagctatca gtcacccact gcagttgaca ttgagccaaa ttatagagcc
    14521 attttcgtag aaagcacaga aaaaacaccc atgaggtaaa ctcttgagtg ctttgaaacg
    14581 ttgatataat gcgatatatt aacgttttga ggcacggaga ctgcgtctcc tttgcagccg
    14641 tattcgtaag cgactaaagc cgcaacgact acgtcaattg cgtcgccagt tctttcaaaa
    14701 aagaaaatac cccatggtaa cccatgaagt attgttctgc tgtattgtag ctggttctta
    14761 acgttttgag aactgactag ctttacgagc tttcttaaga cctggttttg ggtgacaaaa
    14821 accaaatatc tgtaaaagct tatcaaatca agctttcaaa actcattttc attaaatata
    14881 agcactttta acccaatcct acaaataata gattaccatt agattaccaa aactcagttt
    14941 tcggagctta tgtagttgag aaaatctcgt atttactttg cttttatata tccactttat
    15001 actatcatcc cgtcataaca gagcatgatt aaatagttac ataaaaaaca atact
//
LOCUS       DARYNN010000049        14341 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.049, whole genome shotgun sequence.
ACCESSION   DARYNN010000049 DARYNN010000000
VERSION     DARYNN010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14341
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.049"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(81..1361)
                     /locus_tag="TVB59_001581"
     CDS             complement(81..1361)
                     /locus_tag="TVB59_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEL1010453.1"
                     /translation="MKIDKRHLLNYSILLPYLILSVIGLIMVYSTTSVSLIQAQANPF
                     RSVANQGLFWVVSLVAITFIYKLKLNFLTNTKVLTIVMLLEILLLIAARFFTTAINGA
                     HGWIVLGPLRFQPAEYLKIIMVWYLALTFSKMQEKIHQYDYQALTRRKWWPTEWGDLR
                     DWRVYSLIMIVLVAAQPDLGNASIIVLTAIIMFLVSGIGYRWFSAILVLITGLSTAFL
                     GMIAVIGVEKVAKIPVFGYVAKRFSAFFNPFRDLTDSGHQLANSYYAMSNGGWFGRGL
                     GNSIEKRGYLPEAQTDFVFSVVIEELGLIGAGLILALVFFLILRIMNVGIKAKNPFNA
                     MMALGVGGMMLMQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVGVGFVLNIDAN
                     EKKEDILKEAELSYRKSVREENSNSKIININQFQ"
     gene            complement(1569..4352)
                     /gene="ppc"
                     /locus_tag="TVB59_001582"
     CDS             complement(1569..4352)
                     /gene="ppc"
                     /locus_tag="TVB59_001582"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015055932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEL1010454.1"
                     /translation="MSVKKLESYNNQEIIAEEVAILKEILESITRRMIGDEAFARIEE
                     IIDLSEKQDYVLLEQLIAKISNKDMEFISRYFSILPLLINISEDVDLAYEINRQNNTN
                     QDYLGKLALTIASAAEKENAKELLERVTVVPVLTAHPTQVQRKTVLELTNSIHNLLRR
                     YRDVKAGVMNQNKWYSELYRYIDILMQTDIIREKKLKVKNEITNVMQYYNSSLIQAIT
                     ALTSKYKTLAKDKGILLDNPKPINMGMWIGGDRDGNPFVTAETLRLSATVQSEVILRF
                     YIDKLSALYQTFSLSSALTKTSPEVERLASLSSDQSIYRENEPYRRAFHYIQARLTQT
                     LQELIGQPASDQLASRMPATVGSLQSGVTRIVTNSSDQQAPAYKTAAAFKADLVMIEQ
                     SLIAAGDSSLVEGDLQEVLQAVDIFGFFLASIDLRQDSSVQEACVAELLKNAGIVENY
                     SALSEEQKCEVLLKELTEDPRTLSSAAVEKSELLEKELAIYTAARELKDKLGEEVIKQ
                     HIISHTESVSDMFELAIMLKEVGLVDQRQARVQIVPLFETIEDLDNARAIMTQYLSYD
                     IVKSWIATNAGYQEIMLGYSDSNKDGGYLASGWTLYKAQNELTKIGEDNGISITFFHG
                     RGGTVGRGGGPSYEAITSQPFGSIKDRIRLTEQGEIIENKYGNQDVAYYNLEMLISAS
                     INRMVTRMLTNPDEIDGFRKIMDEIVEDSNRIYRELVFDNPHFYDYFFEASPIKEVSS
                     LNIGSRPAARKTITDISGLRAIPWVFSWSQNRIMLPGWYAVGSAFKRFIDKEEGNLAK
                     LQHMYDKWPFFHSLLSNVDMVLSKSNMNIAFQYAQLAESKEVCEVFHTILDEWQLTKN
                     VILAIAQHDELLEETPSLKQSLDFRLPYFNVLNYIQIELIKRLRHEQLDEDYEKLIHT
                     TINGIATGLRNSG"
     gene            4550..6349
                     /gene="pepF"
                     /locus_tag="TVB59_001583"
     CDS             4550..6349
                     /gene="pepF"
                     /locus_tag="TVB59_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEL1010455.1"
                     /translation="MELKKRSEFPENELWDLTALYKDREDFLLAIEKALQDVGLFQRN
                     YEGKLTTAQDFTQALMEIEQIYIQMSHISTYAFMPQTTDFSDEAFAQIAQAGDDFMTK
                     ASVALSFFDTALANADLAVLDELEKNPYFSATIRMAKIQKEHLLSPDVEKALTNLREV
                     INAPYDIYTKMRAGDFEMEDFEVDGKVYKNSFVSYENFYQNHENAAIRDKAFRSFSNG
                     LRKHQNAAAAAYLAKVKSEKLLADMKGYASVFDYLLAEQEVDRSMFDRQIDLIMTEFG
                     PVAQKFLKHVARVNGLDKMTFADWKLDIDNALNPEVSIDGAYDLVMASLAPLGPAYTK
                     EVERYQTERWVDFAANANKDSGGYAADPYKVHPYVLMSWTGRMSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNTHMSTYYVEAPSTFNELMLSDYLEAQFDTPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGGTFGAEQLNAMMKDVLTEFWGDAVEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLNLKNNPNGANEWLDFLKSGGSRTPLETALLIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYTEEIGHD"
     gene            6342..6845
                     /locus_tag="TVB59_001584"
     CDS             6342..6845
                     /locus_tag="TVB59_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEL1010456.1"
                     /translation="MTSIYDFSVKRQDGTDCSLEQYQGKVLLVVNTATKCGLTPQYQA
                     LQELYDTYREQGFEILDFPCNQFLHQAPGDATEINAFCSLTYQTTFPRFAKIKVNGKE
                     TEPLFTWLKEQKSGPLGKCIEWNFAKFLIDQKGQVVERYASKTDPKMIEKALQQLLSQ
                     EPIDQSD"
     gene            7344..8537
                     /locus_tag="TVB59_001585"
     CDS             7344..8537
                     /locus_tag="TVB59_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1010457.1"
                     /translation="MRFQGLTSNFYNLIFSRSSRNIADSFYMIALSVGLLKVYNINAG
                     ELSFLTLVGLLPNMLSFAYGSLIHNLKNDKKWLIVFQMIQLIVIISIIICLSYQLPVV
                     VMYVLNLAFNLVTTVLNTIQMKIVPRTLDDDSDLIEKSVDIQYATSNVLDIVSNFVGS
                     VLLGFVSYLVLLQLSLPFFIGAIAFIFRIQLSPSKLSTTTNDEIEKPASVTESLRAFR
                     ESTFTSFIILVEAFLSGGTDLLLALLPLYLLSEGISIEYIGLVLAAHRAADLLGALVA
                     PRIKVSPRSFFFIDYILSGSSFLLCFMIPYPMVKLLLFFITFTIIGISGNVFEKMIYS
                     EYNHNKLALIYTTNATLYAVFGVLFLLIPFVYSNIRVIGIVINSLTIMIGFGLLIVHL
                     QQERK"
     gene            complement(8736..9200)
                     /locus_tag="TVB59_001586"
     CDS             complement(8736..9200)
                     /locus_tag="TVB59_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010458.1"
                     /translation="MLRLAFSGFLIGQPVMALLLIYLLYVNVAEAILAMTGYVLLLAC
                     FFGFGPWLFWQMACYSMVLVLWGYFLNPLSDRLSQHRLINQALMAGVCTFCYHILLDS
                     CFAYLYSISWWSYIWAGMLFTVTNALATMGYFLVVLLLLKRLSGKKDPKLSA"
     gene            9468..10316
                     /locus_tag="TVB59_001587"
     CDS             9468..10316
                     /locus_tag="TVB59_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEL1010459.1"
                     /translation="MRRRIKPIVVVVFFTLIATLLIIGKAHSDNLKSKELKLAKASIP
                     TNTSTSNKSTTSTSETTEFLLNPIIDVSGWQLPSDIDYDLLASNISAAIVRVYGGSQI
                     TAHNNAAFTTGIDKSFKKHITEFQKRHIPVAVYSYALGRSAKEMRAEARTFYKNASPF
                     NPTYYWIDVEEATMTDMNKGVKAFREELKRLGAENVGLYIGTYFMAEQDISTEGFDAI
                     WIPTYGGDSGYYEAAPDTSLDYDLHQYTSQGYLNGFNNPLDLNQIAVTKDTKKTFEKL
                     FGKVKP"
     regulatory      10725..10821
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            10868..11431
                     /gene="thiT"
                     /locus_tag="TVB59_001588"
     CDS             10868..11431
                     /gene="thiT"
                     /locus_tag="TVB59_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HEL1010460.1"
                     /translation="MSNKTTVTVLIEAAIFAALAMALSFIPDFAGWFSPSYGAIPLVL
                     FSLRRGLRYGLLTGLIWGLLHFILAKIYYLSLSQVIIEYILAFTSMGLAGLFSKPLTN
                     SLGTNKRSFSLLIASAAAFLAIGVRYIWHFIAGVIFWGSYAPKGTSAIWYSFTVNGTA
                     GLLTFIVTLIALLIILPTQPQFFKPSK"
     gene            11592..12071
                     /locus_tag="TVB59_001589"
     CDS             11592..12071
                     /locus_tag="TVB59_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEL1010461.1"
                     /translation="MAKKVKVKKTLVEQILDKAGIPYQALRINALQGDFPDTINPSDI
                     YKTLALTGDKTGPLIGIIPLTEHLSEKKLAGLSGNKKVSMIPQKELQKITGYVHGANN
                     PVGIRQRHNYPIYIDQSALAKQEIIVSAGELGRSIQINSQALADFVGASFADIKENK"
     gene            12068..12433
                     /locus_tag="TVB59_001590"
     CDS             12068..12433
                     /locus_tag="TVB59_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HEL1010462.1"
                     /translation="MRLIGNMIWFIFSGFWAWISWSIVGLILCLTIIGIPFGIQCFKI
                     GALGLFPFGKAIEIGQGAGSLLLNIIWIVCCGWSLAIMHLTSALLLCLTIVGIPFARQ
                     SLKLAKISLFPFGAIIYDI"
     gene            12452..13096
                     /locus_tag="TVB59_001591"
     CDS             12452..13096
                     /locus_tag="TVB59_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEL1010463.1"
                     /translation="MKLYFVRHGKTLWNLEGRFQGANGDSPLLESSKDDLRQLARELW
                     DISFDAIYSSDLKRAVDTARIIVDEANCKTDISYTKQLREWNLGTLEGTKIATVSAIY
                     PSQMSAFYHNLAKFKPSQFKAESLYESTQRLYQLIKSLEDKAYQQVLMVGHGAHLTAS
                     IRALLGFEPGMLRAQGGLDNASLTVIETLDFKHFHCLRWNDTSFLQKKTTRLTP"
     gene            complement(13527..13694)
                     /locus_tag="TVB59_001592"
                     /pseudo
     CDS             complement(13527..13694)
                     /locus_tag="TVB59_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270424.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
     gene            complement(13932..>14341)
                     /locus_tag="TVB59_001593"
     CDS             complement(13932..>14341)
                     /locus_tag="TVB59_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEL1010464.1"
                     /translation="VQRFDTVGKKKLKVDEKYYLTDHGFRQARGYSNTKDIERTLENI
                     VYIELVSRGYRVEIGKVKDLEIDFIASKDNERLYYQVSYLMETEETRKREFGVYDFVR
                     DNYPKFVLSMDKVDFSQNGIIHKNVIDFLLESK"
BASE COUNT         4306 a         3132 c         2687 g         4216 t
ORIGIN      
        1 caactttttg ggggcagtac acctggtcct ctctaaatgt ttgttataag ccacccgcta
       61 cagttgacaa ggagcttttt ttactgaaat tgattaatat taataatctt actattacta
      121 ttttcttccc ggacagactt ccggtaagat agctctgctt cttttaaaat atcctctttc
      181 ttctcattgg catcaatatt gaggacaaag ccaaccccta cagacaagac cagcaggctg
      241 tttcctccct gtgataagaa tggaaaggta acccctgttg aaggaatgag gccagaaatg
      301 ccaccaatgt taacaaatac ctgcatcagc atcatgccac caacaccaag agccatcatg
      361 gcgttaaagg gatttttggc cttaatcccg acattcatga ttctcaaaat aagaaagaaa
      421 acaagcgcaa ggatcaatcc tgccccaatc agccctaact cctcaatcac gacagaaaag
      481 acaaaatctg tctgtgcctc tgggagatag ccccgctttt caatcgaatt tccaagccct
      541 ctgccaaacc agccaccatt gctcatggcg taataagaat tagccagctg atgtcccgaa
      601 tctgtcaaat cacgaaaagg attgaaaaaa gcactaaagc gcttggcaac gtaaccaaaa
      661 actggaatct tagccacctt ttcaacacca atgacagcaa tcattcccaa aaaagcagtt
      721 gacaaaccag taattagcac taaaatggca gaaaaccaac ggtagcctat accactgacc
      781 aaaaacatga taatagctgt caacacgata atagaggcat tgcccaaatc aggctgcgca
      841 gcaaccagca caatcataat caaggaataa acacgccaat cacgcaggtc accccactct
      901 gttggccacc atttgcgacg cgtcaaggcc tgataatcat actgatgaat cttttcctgc
      961 atctttgaaa aggtgagtgc cagataccaa accatgatga tcttcagata ctctgctggc
     1021 tgaaacctca gaggcccaag gacaatccag ccatgcgcgc cattaatcgc tgtcgtaaaa
     1081 aagcgagcag caatcaacag cagtatttca agcagcataa caattgttaa aaccttggta
     1141 ttggtcaaaa aatttagctt tagcttgtaa ataaaggtaa tagcaactaa gctgacaacc
     1201 caaaagagcc cttgattggc aactgaccga aatggattgg cctgagcctg aatcaagcta
     1261 acactggttg tggaataaac catgatcagc ccaatcacag ataaaatcag ataaggtagt
     1321 aatatggagt aatttagcaa atgcctttta tcaattttca tcatttcccc tataatcttg
     1381 agataatcat tagcattata tcatctttca ttggtaaaac aaaggaaaaa tacattgcaa
     1441 gcacctagcc aagcatggct ctagacaaag cttgctgtat ccttggaatc gctcaatcta
     1501 aaaaacacag acaagccatt ataacctagt agcctgtctg tgtgagctgc tgattgatct
     1561 tcaacggctt agccggaatt acgaagtcct gtagcaatac cattaatagt tgtgtggatc
     1621 agcttttcat agtcctcatc tagctgctca tgacgaagac gcttaatcag ctcaatctga
     1681 atgtagttta acacattaaa atatgggagg cggaaatcca agctttgctt caaggacggg
     1741 gtttcctcaa gaagctcatc atgctgtgcg atagcaagaa taacgttctt agtcagctgc
     1801 cactcatcaa gaatggtatg aaagacctca cagacctcct tgctttctgc taactgcgca
     1861 tattgaaagg caatgttcat gtttgatttt gataatacca tatcaacatt agacagcaag
     1921 gaatgaaaga acggccattt gtcatacata tgctgtaatt tggctaaatt tccctcttct
     1981 ttatcaataa aacgcttaaa ggcagagcct actgcatacc agcctggaag catgatccgg
     2041 ttttgtgacc aagaaaatac ccaaggaatg gcacgcaggc ctgagatatc tgtaatggtt
     2101 ttacgagcag cagggcgaga accaatattt aagcttgata cctccttgat cggactggct
     2161 tcaaagaaat aatcatagaa atgcggattg tcaaaaacca gctctcgata aatgcgatta
     2221 ctgtcttcaa caatttcatc catgattttc ctaaagccat caatctcatc aggatttgtc
     2281 agcatacgag tcaccatgcg attgatagaa gcagaaatca gcatttccaa attgtagtaa
     2341 gccacatctt gattgccata tttattttca ataatctcac cctgttccgt caagcggatt
     2401 cggtctttaa tagagccaaa tggctgtgag gtgatcgcct cataggatgg accgccacca
     2461 cgtccaacag tcccaccacg tccatgaaag aaggtgatgc tgataccatt gtcctcccca
     2521 attttggtca gctcattttg cgccttgtaa agtgtccagc cagacgctaa atagccaccg
     2581 tctttgttgc tatctgaata cccaagcata atctcttgat agccagcatt tgtagcaatc
     2641 caagacttga caatatcata gctaaggtat tgtgtcatga tcgctctagc attatccaaa
     2701 tcctcaatcg tttcaaataa aggcacaatc tgcacacgcg cctgacgctg gtcaacgaga
     2761 ccaacctcct ttagcatgat agccagctca aacatatcag aaacactctc tgtatgtgaa
     2821 atgatgtgct gcttaatcac ctcttcacca agcttatcct tgagctcacg tgccgctgta
     2881 tagatagcaa gctccttttc taacagctct gacttttcaa cagctgccga tgagagggtg
     2941 cgagggtctt ctgtcagctc ctttaagagg acctcacatt tttgctcctc tgacaaagca
     3001 ctgtaattct caacaatacc agcatttttc aaaagctcag caacacaggc ctcctgcaca
     3061 ctagaatcct gccgcagatc aatactggct aaaaagaaac caaaaatatc aaccgcttgt
     3121 aggacctctt gcaaatcccc ctcaaccaag gaggaatccc cagctgcaat gagagattgc
     3181 tcaatcatga ccagatcagc cttaaaagct gctgctgtct tataggctgg tgcttgctgg
     3241 tcactgctat tggtcacaat tcttgtaacg cccgactgaa gcgagcctac cgtagcaggc
     3301 attctagatg ctagctggtc tgaggccggc tgaccaatta gctcctgcaa ggtttgggtt
     3361 agacgagcct gaatatagtg aaaagctctg cggtagggct cattctcacg ataaatggac
     3421 tgatcactag atagactggc cagacgctcc acctcaggac tggtctttgt caaggctgac
     3481 gacagcgaaa aggtttgata aagagctgac aatttgtcaa tgtaaaagcg caggataacc
     3541 tcactttgga ctgttgcaga cagcctcagt gtctctgctg tgacaaaagg attgccatct
     3601 cggtcccctc cgatccacat gcccatgtta atcggctttg gattgtccag caagatcccc
     3661 ttgtccttgg ccagcgtctt atacttgctt gtcagcgctg tgatcgcctg tatcagagag
     3721 ctattgtaat actgcatgac attggtaatc tcatttttga ccttgagctt tttctcacga
     3781 atgatatccg tctgcatgag aatatcaatg taacggtaca gctcactata ccatttgttt
     3841 tgattcatga cacccgcctt gacatcacga tagcgacgaa gaaggttatg aatgctattg
     3901 gtcaactcta gaactgtctt tcgctgaacc tgtgttgggt gagctgtcaa gactggaacc
     3961 accgtcaccc tttccaacag ttccttggca ttttcctttt cagcagcaga agcaatggtc
     4021 agagcaagct ttcccagata gtcttgattt gtattgtttt gacgattgat ttcataagcc
     4081 aaatcaacgt cctctgaaat attaatcaac agcggaagaa tcgaaaaata tcgtgaaata
     4141 aattccatat ctttattgct aatcttagcg atcaattgct ctagaagcac ataatcctgt
     4201 ttttcagata ggtctataat ttcctcaatc cttgcaaagg cctcatcacc aatcatgcga
     4261 cgcgtaatgc tctcaagtat ttcctttagg atagcaacct cttcagcaat aatctcctga
     4321 ttattatagc tctctaattt tttgactgac aaatgacgga cttcccttct tatgctagtt
     4381 ttcctcctat cataccactt tttgctaaaa atgtaagcct attggctagg aatgtttgtt
     4441 ttccttgaca tataagattc attggtacaa aaatgtttgt aaagctttta caggctatcg
     4501 cttctaattt ttgttatact ataggtaatt actcatgaag gagaacatta tggaattaaa
     4561 aaaacgttca gaattccctg aaaatgagct ttgggaccta actgccctct acaaagacag
     4621 ggaagatttt ctattggcca ttgaaaaagc cttacaagat gtcggcctat tccaacgcaa
     4681 ttacgaaggc aaattaacaa ctgctcagga ttttacacag gccttgatgg agattgagca
     4741 gatttatatt caaatgagtc atattagcac ctatgccttt atgccacaga ccactgattt
     4801 ttcagatgaa gcatttgctc aaattgccca ggctggtgat gattttatga ccaaggctag
     4861 cgtagccctc agcttctttg atacagccct agctaatgca gaccttgctg ttcttgatga
     4921 attggaaaaa aatccctatt tcagcgcaac tatccgcatg gcgaaaatcc aaaaagagca
     4981 tttgctaagc cctgatgttg aaaaggcact gaccaatcta cgagaagtga tcaacgctcc
     5041 ttacgacatt tacaccaaaa tgcgggctgg agattttgag atggaggatt ttgaagttga
     5101 tggtaaagtc tacaaaaata gctttgtttc ctatgaaaac ttttatcaaa accatgaaaa
     5161 tgctgccatt cgtgacaagg cctttcgttc cttctcaaac ggactgcgta agcaccaaaa
     5221 tgcagcagcc gcagcctatc ttgctaaggt caaatcagaa aagctcttag ctgatatgaa
     5281 gggctatgcg tctgtttttg attacctgct ggctgagcag gaggtggacc gcagcatgtt
     5341 tgaccgtcaa atcgacctca tcatgaccga atttggtcca gttgctcaaa aattcttaaa
     5401 gcatgtggca agggtaaatg gcttagacaa gatgactttt gcagactgga agctagatat
     5461 tgataacgcc ctcaatccag aggtctctat tgatggagct tatgacttgg tgatggcatc
     5521 attagcacca cttggtccag cctatacgaa agaagttgaa cgctaccaaa cagagcgctg
     5581 ggtggacttt gctgcaaatg ccaataagga ttctggtggc tacgctgctg acccttacaa
     5641 ggttcaccct tatgtgctga tgagctggac aggccgtatg tctgacgttt acacgctgat
     5701 ccatgagatt ggccattctg gtcagtttat cttctctgac aatcaccaaa gctacttcaa
     5761 cacacacatg tcaacctatt acgttgaagc accttcaacc ttcaatgagc tgatgctaag
     5821 tgattatttg gaggcacaat ttgacacgcc tcgtcaaaaa cgctttgcac tggcgcaccg
     5881 cttgacagat acttatttcc acaacttcat cacgcatttg ttagaggctg cctttcagcg
     5941 taaggtttat accctcatcg aagagggggg cacctttggt gcagagcagc ttaatgccat
     6001 gatgaaggac gttttaacag agttctgggg cgatgctgtt gagattgatg atgacgctgc
     6061 ccttacctgg atgaggcagg ctcattatta catggggctt tatagctata cctattctgc
     6121 agggcttgtg atttcgactg ccggctacct caatctaaag aataacccaa atggtgccaa
     6181 cgaatggctt gatttcttaa agtctggtgg cagtcgtacc ccgcttgaga cagccctact
     6241 catcggagct gacatctcaa cagacaagcc gcttcgcgat accattcaat tcttgagcga
     6301 tacggttgat cagatcattg cctatacaga ggaaattggt catgactagc atttatgact
     6361 ttagcgttaa aagacaagat ggcactgatt gttcactgga gcaataccaa ggaaaggtcc
     6421 tattagtggt caacaccgcc actaaatgcg gattaactcc tcaatatcaa gcattacaag
     6481 agctttatga cacctacagg gaacaaggct ttgaaatcct tgatttcccc tgcaatcaat
     6541 ttttacatca ggcaccgggt gatgctacag aaatcaatgc cttttgcagc ttaacttacc
     6601 agaccacctt cccacgcttt gccaaaatca aggtcaacgg caaggagaca gagccattat
     6661 tcacttggct caaagaacaa aaaagtggcc cactcggcaa gtgcatcgaa tggaacttcg
     6721 caaaattttt aattgatcaa aaggggcagg ttgttgagcg ctatgcctca aaaacagacc
     6781 ccaaaatgat tgaaaaagcc ctacagcaat tgctttccca agagccaatt gaccaatcag
     6841 actaacgaag tcctatcaaa aaacaagcca agatccttat ttcttggctt gtttttatat
     6901 ctaaagcttc ttgctttgcc gaggagccgc taaaggtcgg ctatttgctt gtctattctt
     6961 caaagaactt ttttgaaggg gaccttgtcc tcacacctaa gcttactttt ttcaatcaaa
     7021 tcattcaagc tgcttcctgt aaggactggt gcacttgagc aatgataact tatgctagcc
     7081 tttttatgtt tatcaaaaag tacctgttca catgatttaa ggacatttac ttcagtcatc
     7141 aacagtaaaa agcattgacg catgtgatta ggattgttaa aatcatctta taaaattaag
     7201 aaaaacacat gactattgaa tgatctaagc tgtgctgcca aaagccctta cccttaatcc
     7261 tatcacagtg gacagcatgc aaatgacctc aggagtttca aatgacattc aaatagattg
     7321 tactgattgg agagtttatc agcatgagat ttcaagggtt aacaagtaac ttttataacc
     7381 tcatttttag taggtcaagt cgcaatatcg cagacagttt ttacatgatt gctttgtctg
     7441 ttggtttact taaggtttac aacattaacg cgggagaact ttcttttttg acattggttg
     7501 gtttattgcc aaatatgctg tcttttgctt atggttcttt aatccataac ttaaaaaatg
     7561 ataaaaaatg gttaattgtc tttcagatga tacagctcat tgtcatcatc agtattatca
     7621 tctgcttaag ctatcagcta ccggttgttg tcatgtatgt gctcaacctt gcctttaact
     7681 tggtcacaac cgtattaaat accattcaaa tgaaaatcgt tcccagaaca ctagacgatg
     7741 attcagacct cattgaaaaa tcagtagata ttcaatatgc tacatcaaac gttctagata
     7801 ttgttagcaa ttttgtgggc tctgttcttc ttggctttgt ttcctatctc gttttactgc
     7861 aattgagcct gcctttcttt ataggagcca tagcttttat ttttaggatt cagcttagcc
     7921 cgtctaagct tagcaccacg actaatgacg agattgaaaa acctgcttct gtaacagaat
     7981 cactacgtgc atttagagag tcgaccttta cttcctttat catcttggta gaagcctttc
     8041 tcagtggagg aaccgattta ttactagcac tccttccatt gtatctactg tctgagggca
     8101 tttcaatcga atacattggc cttgttttag cagctcacag agcagcagat ttattagggg
     8161 ctctggttgc acctcgcatt aaggtatctc cacgaagctt ctttttcatt gattatatcc
     8221 tgtctggaag cagcttcttg ctttgcttta tgattcccta tccgatggta aaattacttt
     8281 tgtttttcat taccttcacg attattggca tatcgggcaa tgtatttgaa aaaatgattt
     8341 atagtgagta taaccacaac aagctcgcct tgatctacac gaccaatgca accttatacg
     8401 ctgtctttgg tgtcctattt ttactgattc cctttgttta tagcaacata agggttatag
     8461 gaatcgtgat caacagcctg acaataatga taggatttgg attactcatc gtccatttac
     8521 agcaagaaag aaaatagctt agttctaaaa ccagcaaaat ggataaagcc cttcaacaaa
     8581 ataagcttcc ttacaaaaag gaatcagaag tcactattaa ataatcaaaa actatcaatc
     8641 gatataagaa gatttaagga gcaaaaaaaa gaaattactg atcggcaaca actgcactac
     8701 taccgggttg ctgcgtcaaa gccagcatta agaccctaag ctgacagctt agggtctttt
     8761 ttgccagata gccttttaag caataaaagc actaccagga aataacccat agtggctaag
     8821 gcattagtca ctgtaaaaag cattcctgcc catatatagc tccaccaaga gatactatag
     8881 aggtaagcaa aacaactatc tagcagtata tgatagcaaa aggtacagac tcctgccatt
     8941 aaggcttgat tgatcaaccg gtgctgcgat agcctgtctg ataagggatt caagaaatac
     9001 ccccacaaaa ccaataccat tgaataacaa gccatttgcc aaaagagcca aggaccaaag
     9061 ccaaaaaagc aggctaataa gagcacatag cccgtcatcg ctaaaatagc ctctgctaca
     9121 ttaacataga gtaggtaaat caacaaaaga gccatgactg gctggccaat gagaaagccg
     9181 ctaaaggcta ggcgcagcaa gaagcaacat acagaaacga tagctagtcg actaataact
     9241 ttggtagaca taatccctct ttgagtgttt tttatctatt atgacagatt ttgcatctct
     9301 tgaccagcat caacagcttt ttgatagatg attacaagac aggtagacta aaatcaaacg
     9361 aaaatagata ggacctgatc tgccaaagct gtcctaagga gctaaaaacc taagaaaatc
     9421 gtaagaccac tttgattttt tgaagcattt aaggtacaat aagactgatg agaagaagaa
     9481 taaaacctat tgttgttgtg gtcttcttta cgctgattgc tactttgtta atcattggaa
     9541 aggctcattc tgataatctc aaaagtaaag agctaaagct tgctaaagca agcattccca
     9601 ctaacactag cacgtccaat aagtcgacta caagcacatc tgaaactact gaatttctac
     9661 taaaccccat tattgatgtt tctggctggc agctgccaag tgacattgat tatgaccttt
     9721 tagcatctaa tatttctgca gcaattgttc gtgtttatgg cggatcacaa attactgccc
     9781 ataataacgc tgcctttact accgggattg ataaatcatt caaaaagcat attactgaat
     9841 ttcaaaaacg acatatccca gttgctgtct atagctatgc tctaggtcgt agtgccaagg
     9901 aaatgcgagc tgaagcaaga accttttaca aaaacgcttc tccttttaac ccaacctatt
     9961 attggattga tgttgaagaa gctaccatga cagacatgaa taaaggggtc aaggcgttta
    10021 gagaggagct aaaacggtta ggtgcagaaa atgttggcct gtatatcggt acttatttta
    10081 tggccgagca ggacatttca acagaaggct ttgacgccat ctggattcct acctacggtg
    10141 gtgattctgg ctattatgag gcagcgccag ataccagcct agattacgac ctgcatcaat
    10201 atacctcaca aggctacctc aatggcttta acaatccatt agatttaaat caaatcgctg
    10261 tcacaaaaga cactaaaaaa acctttgaaa agctttttgg gaaagtaaag ccttaaaggc
    10321 atcgaagcaa gtcgtcaaaa cctttgaatg tcagtcattc cgaatgcctt aaaccctaag
    10381 ctcaaagccc aggtaagcca atcctaaaga aggttgctcc tattcttatt tctttaagaa
    10441 taaagaccct ttcatcaatc taagaaggct aaagattgct ggctgttaaa aaatgctata
    10501 ttgattcctt ctgacgtcaa tttgagcatt aaggacaact gtatttagaa gctgatattg
    10561 ataacaccaa tcactgcttg tttttggttt aaaggctggc tgttagctca gccttttttg
    10621 gtgtgatcag tttttgacta taccgctatg ccaactttgt ctcatgattt caaggccaaa
    10681 ttcttgacat tgctgccatc tcattttata atatagaaaa tataattatc acaaaggagt
    10741 gctttggctg agatcgcgta tgcgaaatcc taaggacctg atcttgttaa tacaagcgta
    10801 gggattgtga ccaatatcat tagcattgga aaacgattct ctttttgtgt gcaaaaggag
    10861 tttttttatg tcaaacaaga caactgttac tgttctgatt gaggctgcta tttttgctgc
    10921 tcttgctatg gctttatcat ttataccaga ttttgccggc tggtttagcc cctcttatgg
    10981 tgctattcct ctcgtcttat tttcgcttag gcgtggcctc aggtatggcc tgctaactgg
    11041 cttgatttgg gggctgctcc attttatttt agcaaagatt tactacctca gtctatctca
    11101 ggttattatt gaatatatcc ttgcctttac ctcaatgggc ttagctggcc tgttttctaa
    11161 gcccttgact aatagtctag gtaccaataa aagatccttc agccttctaa ttgctagcgc
    11221 agctgccttt ttagcgattg gggttcgtta tatctggcat tttatcgctg gtgttatttt
    11281 ctgggggagc tatgctccta agggcacctc tgctatttgg tattccttta ctgtcaatgg
    11341 cacagcaggt cttctaacct ttatcgtgac acttattgcc ctgctcatta tcctaccgac
    11401 acaaccacaa ttttttaagc ctagtaaata agacaagagt tcgaatcgga aaatcataaa
    11461 gctgaggcag gtctgtaaag gcctgctctt tctaagccta gaaaaaggat caaaaaagac
    11521 tttttttcag tctaatggta tactactact gttagactgt ttttgatatt gacacataag
    11581 gaagttaaca aatggctaaa aaggtaaaag taaagaaaac gctggtggag caaatcctag
    11641 acaaggcagg tatcccctat caagcgctta ggatcaatgc cttacaaggt gatttcccag
    11701 acacaatcaa cccatcagat atttataaaa ccctagcact gactggcgat aagacaggcc
    11761 ccttgattgg gattattcct ttgacagagc atttatctga aaagaagcta gcaggccttt
    11821 ctggaaacaa aaaggtctcc atgattcctc aaaaggagct gcaaaaaata accggctatg
    11881 ttcatggtgc aaacaatcca gttggtattc gacaaaggca caattaccct atttacatcg
    11941 accagtctgc actagccaag caagaaatta tcgtatcagc tggtgagctt ggtcgatcca
    12001 tacagatcaa tagtcaagcc ctagcagatt ttgttggggc tagctttgct gacataaagg
    12061 agaacaaatg agacttattg gaaatatgat ttggtttatt ttttcaggct tttgggcctg
    12121 gatttcttgg tctattgttg ggcttatcct atgcttaaca attatcggga ttccttttgg
    12181 gatacaatgc ttcaagatag gcgctttggg tctttttcct tttggaaaag ccatcgaaat
    12241 tggccaagga gcaggcagcc tgctgctcaa tatcatctgg attgtctgct gtggctggag
    12301 cttagcgatc atgcatttga cttctgccct tctcttgtgc ctcacgattg ttggcattcc
    12361 atttgcccgg caatctctaa aattggccaa gattagcctc tttccttttg gagccatcat
    12421 ttatgacatt taattaggaa gcaaaagact tatgaaattg tattttgtca gacatggtaa
    12481 aaccttgtgg aacctagagg gccgttttca gggagctaac ggagattcgc ccttgcttga
    12541 aagctctaag gacgatttgc gccagctagc aagagagctg tgggacattt cttttgatgc
    12601 gatctactcc agcgacctaa aaagagctgt tgatactgct cgcattattg tggacgaagc
    12661 taactgcaag actgatatta gttataccaa gcagctgaga gaatggaacc taggcaccct
    12721 ggaaggaacc aaaatagcaa ctgtatccgc catctacccc agtcagatgt cagcctttta
    12781 tcacaattta gccaaattca agcccagtca atttaaggct gaatcccttt atgaaagcac
    12841 acaaaggctt tatcagctca ttaaaagttt ggaagataag gcctatcagc aggttttaat
    12901 ggtaggacat ggcgcccatt tgacagcttc tattcgtgct cttttaggct ttgagccagg
    12961 tatgcttcgg gcacagggag gactggataa tgccagccta accgttatag aaaccttgga
    13021 tttcaaacac tttcattgtc taaggtggaa tgatacatca tttttacaaa aaaagactac
    13081 tagattaaca ccctagtagc tcttaagcac aaagctccaa gacagctaaa ctgtactcca
    13141 ttggttagag aacacatctc attttttgag ggacgcttta ttagctgtag gaagttatga
    13201 aaagctaaat acacgagagg actaaattgg acaagctcaa aagtttgaca atgtatttca
    13261 aaaaaggatt gaattctgta tcgaacagga ctcagtcctt tttatcattt atcaagccga
    13321 ccaaggcttt caaccacgac aaacgcgcaa aacagttatt tcctgatgat agtagagact
    13381 acagcagata ttttcaatga ttttcttgta gtaacatcta tacaaaacaa tacagctcat
    13441 tgaaatatag gaacattaaa attcagaaag atttcttttc ttgctaaaaa tctttcatcc
    13501 atttcaaact ggttttcatt tgtcctctcc tttttcagtt ctgctttttc tccataagct
    13561 gcacagttga tgtactcctt gcctttaccg tacttcttta caaatgtaaa atttacaact
    13621 tatacttctt ctccttctct ttcaaaactt gagtaaattg attctgctac taaatttgcg
    13681 ttaatattaa tcatttttta tccataattt ttctcctttt ttaatttaaa attcccatta
    13741 aaaaagcgac tggacttttt ccaatcgctg atacttctac tattttattt ttatttcggt
    13801 agaacttcta atccttatca tctatatcct cctttttaaa cacaaaaaag acggtagatt
    13861 ttttcttttt ccattgtctc ttataactta tatttaattt ttgaatagta tgcaaacatt
    13921 taaggaaaca actacttgct ttccaataaa aagtcaatca catttttgtg aataattcca
    13981 ttttgactaa aatccacttt atccatggat aagacaaatt taggataatt atctctaaca
    14041 aaatcataca caccaaactc tcgttttctt gtttcttctg tttccatcaa ataagaaacc
    14101 tgataatata acctttcatt atccttactt gcaataaaat caatttccaa gtcttttact
    14161 ttgccgattt caactctata tcctcttgaa acaagttcaa tataaacgat attttccaat
    14221 gttctttcaa tatcctttgt attggagtat cctcttgcct gcctaaatcc atgatctgta
    14281 agataatatt tttcatcaac ctttaacttc ttttttccta cagtatcaaa tctttgtact
    14341 t
//
LOCUS       DARYNN010000050        13956 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.050, whole genome shotgun sequence.
ACCESSION   DARYNN010000050 DARYNN010000000
VERSION     DARYNN010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13956
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.050"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            102..1115
                     /gene="pfkA"
                     /locus_tag="TVB59_001594"
     CDS             102..1115
                     /gene="pfkA"
                     /locus_tag="TVB59_001594"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEL1010465.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRKAISEGMEVYGINRGYAGM
                     VDGDIFPLGSKEVGDKISRGGTFLYSARYPEFAQLEGQLAGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAVGIPGTIDNDIAGTDYTIGFDTAVNTAVEAIDKLRDTSSSH
                     GRTFVVEVMGRNAGDIALWAGIASGADQIIVPEEEFDIHKVVSTIKDDFENRGKNHHI
                     IVLAEGVMSGEAFAQQLKEAGDESDLRVTNLGHILRGGSPTARDRVIASWMGAHAVEL
                     LKEGKGGLAVGIHNEELVESPILGSAEDGALFSLTDEGNIVVNNPHKARLDYAALNRS
                     LAQ"
     gene            1177..2679
                     /gene="pyk"
                     /locus_tag="TVB59_001595"
     CDS             1177..2679
                     /gene="pyk"
                     /locus_tag="TVB59_001595"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEL1010466.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKYGEDGYWAGQLDVEQSAKKIAE
                     LIEAGANVFRFNFSHGDHKEQGDRMATVRLAEKLARQKVGFLLDTKGPEMRTELFADD
                     AKEYSYVTGERIRVATAQGIQSTRDMIALNVAGALDIYDEVEVGHTILIDDGKLGLKV
                     IEKDIAKREFIVEVENDGIIAKQKGVNIPNTKIPFPALAERDNADIRFGLEQGLNFIA
                     ISFVRTAKDVEEVREICRETGNEHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVFQKMIITKVNAAGKAVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPVEAVRTMATIDKNAQTLLNEYGRLDSSAFPRTNKTDVIASAVK
                     DATHSMDIKLVVTITETGNTARAISKFRPDADILAVTFDEKVQRALMINWGVIPVLAE
                     RPASTDDMFEVAERVALETGLVQSGDNIVIVAGVPVGTGGTNTMRVRTVK"
     gene            2808..3365
                     /gene="lepB"
                     /locus_tag="TVB59_001596"
     CDS             2808..3365
                     /gene="lepB"
                     /locus_tag="TVB59_001596"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEL1010467.1"
                     /translation="MVKRDFIRNILLLLILIVGAVLLRIFVFSTYRVTSEASNAYLNK
                     GDLITIKKNIEPKYKDFVVYTVDKKDYVSRVVAVAGDRVTYMDDIFYLNNMVESQSYL
                     ESMKAKYLNHAPIGTLYTEDFTISTVTSGKYDSIPKGKYLLLNDNRKNHHDSRQFGLI
                     DVSQIKGLVTFRVLPLKDFGFVEVE"
     gene            3542..5353
                     /gene="glmS"
                     /locus_tag="TVB59_001597"
     CDS             3542..5353
                     /gene="glmS"
                     /locus_tag="TVB59_001597"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019804802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEL1010468.1"
                     /translation="MCGIVGVVGSRNATDILMQGLEKLEYRGYDSAGIFVSDGRTSNL
                     VKSVGRIADLRSKIGIDVVGTTGIGHTRWATHGQATEENAHPHTSQTGRFVLVHNGVI
                     ENYLQMKEQYLAGHTFKGQTDTEIAVHLIGAFVEEGCSVLEAFKKALSIIEGSYAFAL
                     IDTEDMDTIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETSEFMEIHDKELVILTKDS
                     ARVTDYAGNPIDRQSYTAELDLSDIGKGTYPFYMLKEIDEQPTVMRRLISTYADAKGQ
                     MMIDPAIIRSVQEADRIYILAAGTSYHAGFASKSMLEHLTDTPVELGVASEWGYNMPL
                     LSKKPMFILLSQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREATYTMLLHAGP
                     EIAVASTKAYTAQVAALAFLAKAVGEANGKKEAISFDLVHELSLVAQSIEATLSDKEL
                     IAEKVQTLLATTRNAFYIGRGNDYYVAMEAALKLKEISYIQCEGFAAGELKHGTISLI
                     EDGTPVIGLISSSELVAAHTRGNIQEVAARGAHVLTVVEEGLEREGDDIIINKVHPFL
                     APIAMVIPTQLIAYYASLQRGLDVDKPRNLAKAVTVE"
     gene            5537..5872
                     /locus_tag="TVB59_001598"
     CDS             5537..5872
                     /locus_tag="TVB59_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEL1010469.1"
                     /translation="MTLPNCLQCDSEYVYEDGHLLICPMCSFEWTRGEEEPEEEGLVV
                     LDSNGTRLADGDTVTIIKDLKVKGAPKDLKQGTRVKHIRLVEGDHNIDCKIDGFGAMK
                     LKSEFVKKI"
     gene            5979..6620
                     /locus_tag="TVB59_001599"
     CDS             5979..6620
                     /locus_tag="TVB59_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEL1010470.1"
                     /translation="MTYIMQVLPSLLDGALITLQVFFIVIVLSIPLGALLAFLMRVDF
                     KPLQWLLTLYIWVMRGTPLLLQLIFFYYVLPSVGVTFDRMPAAILAFTLNYAAYFAEI
                     FRGGIETIPNGQYEAAKVLKLSPVQTVRYVILPQVFKIVLPSVFNEVINLVKDSSLVY
                     VLGVGDLLLASKTAANRDATLAPMFIAGLIYLLLIGLVTILSKQVEKRFNYYQ"
     gene            6630..7259
                     /locus_tag="TVB59_001600"
     CDS             6630..7259
                     /locus_tag="TVB59_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL1010471.1"
                     /translation="MLELNNISKRFGHKQIFDGFHLTVEDGEVLSLVGPSGGGKTTLL
                     RMLAGLEPIDSGNISYNGESVPIDHLEKRSLLGFVFQDFQLFPHLTVLDNLILSPTIT
                     MAMPRPDAKQKAMELLERLGLKEHAAAYPYALSGGQKQRVALARAMMIDPQIVGYDEP
                     TSALDSELRQEVEKLILQNREMGITQIVVTHDLQFAQTISDRIIKINPK"
     gene            7276..8112
                     /locus_tag="TVB59_001601"
     CDS             7276..8112
                     /locus_tag="TVB59_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL1010472.1"
                     /translation="MTLKKTLLVALFAATATLLVACGASNKQTSSDAWDSYKQKKTIT
                     LGFDNTFVPMGYKDESGKNTGFDIELAKAVFDQYGINVKYQAINWDLKETELNNGKID
                     LIWNGYSVTKERQAKVAFTEPYMKNEQVLVTQKSSQISSFADMKNKTLGAQSGSSGYD
                     AFTSHPKVLKDLVKGNDATQYETFTQAFIDLKNKRIDGLLIDRVYANYYLQQEGELDR
                     YNIIASEFEGEDFAVGVRKADKTLQKKITQALKSLYQDGTFQKISKKWFGEDVATVQL
                     KS"
     gene            complement(8208..9446)
                     /locus_tag="TVB59_001602"
     CDS             complement(8208..9446)
                     /locus_tag="TVB59_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEL1010473.1"
                     /translation="MPNNPVENLRLAKRGPIVSIVTYLALSITKLLAGYLLNASSLIA
                     DGFNNLSDIVGNVTLLIGLHLASQPADANHRFGHWKIEDLSSLITSFIMFIVGFQVLL
                     QTIQQMISGKQSAIDPLGAIVGIASALVMLGVYAFNKALSKKVRSSALVAASKDNLSD
                     AVTSIGTSIAIIAASLKLPIIDRLAALIITFFILKTAFDIFMASAFSLSDGFDSTQLK
                     AYEKAILKIPKIIAVKSQRGRTYGSNVYLDIVLEMHPDLSVYESHAITEQVEQLLSEQ
                     FAVYDIDIHVEPAKLPKDDNCEYVYKKLYKNEKIMLSQIPDYQELIAKTFTFIDRDGQ
                     AYNAKQFLEQQRSSSNQLEAFCMQSISHNTKLVTYQLQGNQHTSIWRRHEAWHLIYHQ
                     ITPITNSIAIKKHYHIKRIS"
     gene            complement(9549..10883)
                     /locus_tag="TVB59_001603"
     CDS             complement(9549..10883)
                     /locus_tag="TVB59_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEL1010474.1"
                     /translation="MIAAAKWIDDLVWGAPLLLLLLGTGIYLTSRLSLLQVIKLPKAF
                     RLIFAKNEGQGDISSFAALATALAATVGTGNIVGVATAIKSGGPGALFWMWVAAFFGM
                     ATKYSEGVLAIKYRTKDANGQISGGPMYYILNGMGQKWRPLANLFAVSGILVALFGIG
                     TFAQVNAITSSLHHSLGISSPLISVLLAAVVAMIIFGGIQAIAKVAETVVPFMAIFYI
                     GASLTVIAVHYTKLLPMLVLIFKSAITPTAAIGGFAGSLVKDAIQKGIARGVFSNESG
                     LGSAPIAAAAAKTKEPVEQGLISMTGTFIDTIIICTLTGLAILVTGQWTSALEGAPLT
                     QSAFASIFGHMGTYALTLSLVLFAFTTILGWSYYGERCFIFLFGTTHLSYFRLIFVIM
                     VGLGGFLKLELIWILADIVNGLMALPNLIALLALSPVVIFETRAYFKRQSTK"
     regulatory      complement(11012..11098)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            11363..13654
                     /gene="pcrA"
                     /locus_tag="TVB59_001604"
     CDS             11363..13654
                     /gene="pcrA"
                     /locus_tag="TVB59_001604"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEL1010475.1"
                     /translation="MNPLLDGMNDKQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKYVNPWNILAITFTNKAAREMRERALALSPATKDTLIATFHSMCVRILRREADHI
                     GYNRNFTIVDPGEQRTLMKRIVKALNLDPKKWSERSILATISNAKNDLLDERAYELGA
                     SDLYSQTVARCYKAYQEELRRSEAMDFDDLIMMTLRLFDQNPDVLAYYQQRYQYIHVD
                     EYQDTNHAQYQLVTLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPDARVVL
                     LEENYRSTKKILQAANEVIQHNRHRRPKKLWTQNADGEQIVYYRANDERDEAVFVAST
                     ISNMCLELGKSFKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDVIA
                     YLTVVANPSDNLSFERIVNEPKRGVGPGTLDKLRQFAYGQGQSLLEAASSLEQSPLKG
                     KAAQAMLALASLLSDLRADLDQLSITALAEALLEKTGYLDMLRVQNTLESQARIENIE
                     EFLSVTKSFDDLSAQQQEHEAGIDRLGRFLNDLALIADSDDGNAETAEVTLMTLHAAK
                     GLEFPVVFLIGMEEGVFPLARAAEDQDELEEERRLAYVGITRAEECLFLTNANTRTLF
                     GKSSYNRPTRFLKEMSENLLSFQGLARPAHASFGVTFSQQGQRQFGTGMSLSEAIQSR
                     KSMAQPARAASTSTPLPFGPNAATSKQAVDWQIGDIAHHKKWGAGTVLEVKGSGKTME
                     LTISFPDVGLKKLLASVAPIEKK"
BASE COUNT         4073 a         2603 c         3261 g         4019 t
ORIGIN      
        1 gttgaaaacg gtttttcgat aaaaatagcg aattagtgaa gtaatttgca aacgaatgtg
       61 ctataataaa aacgttaaat taattaaagg agtaccaaaa aatgaaacgt attgctgttt
      121 taaccagtgg tggtgacgcc cctggtatga atgctgctat tcgtgcagtt gttcgtaaag
      181 caatttcaga aggaatggaa gtctatggta ttaaccgcgg ctatgctggt atggttgatg
      241 gtgatatctt tccactaggc tcaaaagagg ttggtgataa gatttctcgc ggcgggacct
      301 tcctttattc agctcgctac ccagagtttg ctcagcttga ggggcaattg gctggtattg
      361 agcagctaaa aaagcatggc attgaagggg tagttgtcat tggtggtgat ggttcttacc
      421 atggtgcgat gcgcttgact gagcatggct tccctgcagt aggtatccca gggacgattg
      481 ataacgatat tgctggaaca gactatacta tcggatttga cactgcggtc aatactgcgg
      541 tagaggctat tgataagctt cgcgatacct catcaagtca tggacggacc tttgttgttg
      601 aagtgatggg acgcaatgca ggtgatatcg cactttgggc aggtattgca agtggagcag
      661 atcaaatcat cgttcctgaa gaggaatttg acattcataa agtggtctca acaattaaag
      721 acgattttga aaatagagga aaaaatcacc atattatcgt tttagctgag ggtgttatga
      781 gtggcgaggc ctttgcgcag cagctaaaag aagctggaga tgaaagtgac cttcgtgtga
      841 caaaccttgg tcatatcctt cgcggtggct ctccaactgc gcgtgatcgt gtgattgcgt
      901 catggatggg agcgcacgct gttgagttgc tcaaggaagg caaaggtggc ttggctgttg
      961 gtattcataa tgaagagctt gttgaaagtc cgattcttgg aagtgcagag gacggtgcct
     1021 tgttcagcct tactgatgag ggtaacattg ttgttaataa cccgcacaag gctcgcttag
     1081 actatgctgc tttgaaccgt tcattagcac aataggataa gtaagatctg gtaatctttg
     1141 ttaatcaact aaaaaataag ggagtttcat aataaaatga ataaacgtgt aaaaattgtt
     1201 gcaacacttg gtcctgcggt tgaaattcgc ggtggtaaaa aatatggtga ggacggctat
     1261 tgggctggtc agttggacgt tgaacaatca gctaaaaaga tcgctgaatt gattgaagca
     1321 ggtgctaatg ttttccgctt taacttctca catggtgacc acaaagagca gggtgaccgt
     1381 atggctactg ttcgtcttgc tgaaaagctg gcacgtcaaa aggttggttt ccttttggat
     1441 acaaaaggac cagaaatgcg tacagaattg tttgctgacg atgccaaaga atatagctat
     1501 gtgactggtg agcgtattcg tgttgcgaca gcacaaggca ttcaatcaac tcgtgatatg
     1561 attgccttga atgtagctgg tgctcttgat atttatgatg aggttgaggt tggccacact
     1621 attcttattg acgatggaaa gcttggctta aaggttatcg agaaggacat tgcaaagcgt
     1681 gagttcatcg ttgaggttga aaatgatggc atcattgcaa agcaaaaggg tgttaatatc
     1741 cctaatacca agattccttt cccagcctta gcagaacgtg ataatgctga tattcgtttt
     1801 ggtcttgagc aaggtcttaa ctttattgct atttcatttg ttcgtactgc caaggacgtt
     1861 gaagaggttc gtgagatttg tcgtgaaaca ggcaatgagc atgttcaatt atttgctaaa
     1921 atcgaaaacc aacaaggtat tgataacctt gatgaaatca tcgaagctgc agatggtatc
     1981 atgattgctc gtggtgatat ggggattgag gtgccatttg aaatggttcc agtcttccaa
     2041 aaaatgatta tcaccaaggt aaatgcagca ggtaaagcag tcatcaccgc aactaacatg
     2101 cttgaaacaa tgactgaaaa accacgtgca actcgttcag aggtatctga cgttttcaac
     2161 gcggttattg acggtacaga tgcgacaatg ctttctggtg aatcagcaaa tggtaaatac
     2221 cctgttgaag cagttcgtac aatggctaca attgataaaa atgcacaaac tcttcttaat
     2281 gagtatggtc gtttagattc atctgccttc ccacgtacca ataaaactga cgtgattgct
     2341 tcagctgtta aagatgcaac acactcaatg gatatcaagc ttgttgtgac catcactgaa
     2401 acaggaaaca cagctcgtgc catttctaag ttccgtcctg atgctgacat cttggctgtg
     2461 acctttgatg aaaaggttca acgtgccttg atgattaact ggggtgtgat tccagtgctt
     2521 gctgaaagac cagcatcaac agatgatatg tttgaggtag cagagcgtgt agctcttgag
     2581 actggtttgg tgcaatcagg agataatatc gttattgttg caggtgtgcc agttggtaca
     2641 ggtggtacaa atacaatgcg tgttcgcact gtaaaataat agctttccat aagctttagc
     2701 tattttgctc tatcagataa tttaaggcaa acaatgatac ttaaaaattg tttgcttttt
     2761 ttattagtca tatcatgtta taatgagact atagactagg agttattatg gtaaagcgag
     2821 attttataag aaatatattg ttgttattga ttcttattgt gggagctgtc cttcttagaa
     2881 tatttgtttt ttcgacctat cgagtcacgt cagaggcttc aaatgcctat ttgaataagg
     2941 gcgatttaat caccattaag aaaaatattg agcctaaata taaggatttt gtggtttata
     3001 cggttgacaa aaaggattat gtgagccggg ttgtagcagt agcaggtgat cgtgttacct
     3061 atatggacga tattttttac ctgaacaata tggttgaatc ccaatcctac cttgagagta
     3121 tgaaggcaaa gtatctcaat catgccccta ttggtacgct ttatacggag gattttacga
     3181 tttcgacggt tacttctgga aaatacgata gcattcccaa ggggaaatac cttttgctaa
     3241 atgataacag aaaaaaccat catgatagcc gtcagtttgg cttaattgac gtgtcacaaa
     3301 ttaagggatt agtaacattt agagtgcttc ctttgaaaga ctttggattt gtagaggtag
     3361 agtagcttta aggctgctct attttgtttc tcaaaatatg actataccaa ttttcttgtt
     3421 gacaagattt ttctgaagtt atatactcta aatataacgt tttagtcggt ttatatctga
     3481 ctataccaat tatattgatc attaaagaaa gtagtaagct agcttactga ggtgttaagt
     3541 tatgtgtgga attgttggag ttgtaggtag tcgtaatgcg actgacatct tgatgcaggg
     3601 attggaaaaa ttagagtatc gtggttatga ttcagctggt atttttgtgt cagatggcag
     3661 gacgtccaat ttggtaaaat ctgttggacg cattgcagat ttacgctcta agattggcat
     3721 tgatgttgtt ggaacgaccg gtattggtca tacacgttgg gcaacgcatg gtcaagcaac
     3781 agaggaaaat gctcaccctc atacctctca gacaggtcgc tttgttcttg ttcataatgg
     3841 tgtgattgaa aattacctcc agatgaagga gcagtacctt gctggacaca cgtttaaagg
     3901 acaaacagac accgaaattg cagttcattt gattggagca tttgttgaag aaggctgttc
     3961 agtcttagag gcttttaaaa aggctttatc aatcattgaa ggctcctatg cctttgcttt
     4021 gattgataca gaggatatgg atacgatcta tgtcgctaag aataaatccc cattgctgat
     4081 tggccttggt gagggctata acatggtttg ttcagacgct atggccatga ttcgtgaaac
     4141 cagcgaattt atggaaatcc atgacaagga gctggttatc ctgacaaagg attcagcaag
     4201 ggtgacagat tatgctggca atccgattga tcgtcagtca tatacagcag agcttgatct
     4261 ttcagatatt ggcaagggga cctatccatt ttatatgcta aaggaaattg acgagcagcc
     4321 aacagtgatg cgtcgcttga tttcaaccta tgcagacgcc aagggacaga tgatgattga
     4381 tccagctatc ataaggtctg tccaagaggc tgatcgtatc tatattcttg cagctgggac
     4441 ctcttatcat gctggctttg cttctaagtc aatgctggag catttgactg atacacctgt
     4501 tgaattaggg gttgcttctg agtggggcta caatatgccg ctattgagca aaaagccaat
     4561 gtttatcctc ttgagccagt ccggtgagac agcagatagc cgtcaggttt tggtcaaggc
     4621 aaatgagatg gggattccaa gcctaacagt gacaaatgtt cctggctcaa ccctatcacg
     4681 tgaagcaacc tacactatgc tgctccatgc aggtccagaa attgcagttg catcaactaa
     4741 agcctacaca gcacaggtcg ctgcacttgc ctttctagct aaggcagttg gtgaggctaa
     4801 tggcaagaag gaagctatta gctttgattt ggttcatgaa ttgtcattgg tcgctcagtc
     4861 tattgaggcc accttatctg acaaggagct gattgctgag aaggtgcaga ccttattggc
     4921 aacaacacgc aatgcgtttt acattggtcg tggcaatgat tattatgttg ctatggaggc
     4981 tgcactaaaa ttaaaagaaa tttcatacat tcagtgtgaa gggtttgcag ctggtgagct
     5041 aaagcatggg actatttcac tgattgagga tggcacacct gttattggac ttatttcttc
     5101 aagtgagctg gttgctgcac atacacgtgg caatatccaa gaggtggctg cacgtggcgc
     5161 tcatgtgttg acagttgttg aggagggctt agagcgtgag ggagatgaca ttattattaa
     5221 taaggtgcac ccattcttag cgccgattgc tatggttatt ccgactcaat taattgctta
     5281 ctatgcttcc ttgcagcgtg gtttagatgt agataagcct cgtaatttag ccaaggctgt
     5341 tacagttgag taatagttgc ctgcttaaaa tgaggcagca gggtcctgaa gcctatttga
     5401 aacgagcttg acatgatgtt atgtcaggct cgttttttag tgcttgcctg gtcttatgat
     5461 aacgtattca tcttgtcaaa taagcatttc tgaagtaaaa tattaacgtt aagactaaga
     5521 agcttaggag agtaagatga cgttaccaaa ttgtttacaa tgcgattcag aatatgttta
     5581 tgaggacggg catttgctca tttgtccgat gtgttccttt gaatggacac gtggtgagga
     5641 ggagcctgag gaggaggggc ttgtcgtttt agatagtaat ggaactagat tagctgatgg
     5701 agacactgtt acgatcatta aggacctgaa ggtcaaggga gcgccgaagg atctcaagca
     5761 gggaactcgt gttaagcata ttcgtcttgt tgaaggtgat cacaatattg attgtaagat
     5821 tgatggcttt ggtgcaatga agctaaaatc agaattcgtc aagaagattt aataacaata
     5881 agcaaccaga tgactggttg tatttttata gaaaagtact tttcaatcca tcagaaaatt
     5941 tggtataatg gataaactat ttatatctag gagacaacat gacgtatatt atgcaggttt
     6001 tacccagctt gctggatggt gccttaatca ctttacaggt tttctttatt gtaattgtat
     6061 tatccattcc cttaggggct cttttagctt ttttgatgag ggttgacttt aagcccttgc
     6121 agtggctatt gacgctctat atttgggtca tgaggggaac acccttattg ttacagctca
     6181 tcttttttta ttatgttttg ccaagtgtgg gtgttacctt tgatcgtatg ccggcagcga
     6241 ttttggcttt taccttaaac tatgctgctt attttgccga gatttttcgt ggcgggatag
     6301 agactattcc aaatgggcaa tatgaggctg caaaggtgct gaagcttagt ccggtacaaa
     6361 ctgttcgcta tgttatcttg cctcaggtgt tcaagattgt tttaccaagt gttttcaatg
     6421 aggtgattaa cttagttaag gattcttcct tggtatatgt gttaggagta ggggatttgc
     6481 tattagcaag caagactgcg gcaaatagag atgcaacctt agcaccgatg tttattgcag
     6541 gtttgattta tttgctctta attggtttgg tcaccatttt atcgaagcag gttgaaaaaa
     6601 gatttaatta ttatcagtaa gggggtcata tgttagaact gaacaatatt tcaaagcgat
     6661 ttggtcacaa gcagatcttt gatggctttc atttgaccgt tgaagatggt gaggttttat
     6721 ctttggtagg gccatctggt ggtggcaaga ctactctgct ccgaatgctg gctggcttag
     6781 agcctattga ttcgggaaat attagctata atggcgagtc tgttcctatt gatcatttag
     6841 aaaaaagaag cctgcttggt tttgtttttc aggatttcca attgtttcca catttgacgg
     6901 tgctggataa tctcatcttg tctcctacca ttaccatggc tatgccaagg cctgatgcaa
     6961 agcaaaaggc tatggagctg ctggagcgcc taggtctcaa agagcatgca gctgcttatc
     7021 cttatgcgct atctggtggg caaaagcaaa gagttgcctt ggctagagcg atgatgattg
     7081 acccacagat tgtaggctat gatgagccga caagtgcctt agactctgaa ttacgtcagg
     7141 aggttgagaa attgattttg caaaatcgtg agatgggcat tacccagatt gttgtcaccc
     7201 atgatttgca gtttgctcag accatttctg atcgtatcat caagatcaat cctaaataga
     7261 agaagaggta gtgctatgac gttaaaaaag acccttctag tagccctatt tgctgctaca
     7321 gctacgcttt tagtagcttg tggcgctagt aataaacaga ctagctcaga tgcttgggat
     7381 tcctacaagc agaaaaagac gattacgctt ggctttgata atacttttgt gccaatgggc
     7441 tataaggacg agtcaggaaa aaataccggc tttgatattg agctagcaaa ggctgttttt
     7501 gaccaatatg gtatcaatgt taagtatcaa gccattaact gggatctcaa agaaactgag
     7561 ttgaacaatg gtaaaattga cctgatttgg aatggctatt ctgtgacaaa agagcgccaa
     7621 gctaaggtgg cctttacaga gccttatatg aaaaatgagc aagtcttagt gacgcaaaaa
     7681 tcatcgcaaa taagctcatt tgctgatatg aaaaataaga ccttaggtgc ccagtctggc
     7741 tcatctggct atgatgcctt tacgagtcat cctaaggtgc taaaggatct tgtcaaggga
     7801 aatgacgcta cccaatatga aacctttaca caagccttta tcgatttaaa aaacaagcgt
     7861 attgatggcc ttttgattga tagggtttat gccaattatt accttcagca agaaggtgag
     7921 ctagaccgct ataacattat cgcgagtgag tttgaaggtg aggattttgc agttggtgtc
     7981 cgaaaagcgg ataaaaccct acaaaaaaag attacacaag ccttaaaatc gctttatcag
     8041 gacggtacct tccaaaaaat ctctaaaaaa tggtttggtg aagatgtcgc aacagttcag
     8101 ttgaaatcat aagacgcaag caagacctaa tcagctcaga ggggttgaga ctagatacat
     8161 ttaaaagact taccttctaa aggcaagtct ttttatacgg cttattatta gctgatacgc
     8221 ttgatatgat agtgtttttt aattgctatg gagtttgtta ttggtgtgat ttgatgatat
     8281 atcaggtgcc aagcttcgtg tcgtctccag atactggtat gctgattgcc ctgtagctga
     8341 taggtgacta gcttggtgtt gtggctgatg gattgcatac aaaaggcttc aagctgattg
     8401 gaagaagaac gctgctgctc taaaaattgc ttggcattgt aagcttgtcc atcgcgatca
     8461 ataaaggtaa aggtcttggc aatgagctct tgataatctg ggatttgact tagcatgatt
     8521 ttctcgtttt tgtagagctt tttgtaaaca tattcacagt tgtcatcttt aggaagcttt
     8581 gcaggctcaa catgaatatc aatatcataa acagcaaatt gctcactcaa gagctgttcg
     8641 acctgctcgg ttatggcgtg actttcataa acagaaaggt cagggtgcat ctcaaggaca
     8701 atatctaaat agacattgct tccgtaagtg cggccgcgct gtgatttgac agcaatgatt
     8761 ttgggaattt tcaatatggc cttttcatat gctttgagct gcgtgctgtc aaagccatct
     8821 gataagctaa aggcgcttgc cataaaaata tcaaaggctg tttttagaat gaaaaaggta
     8881 atgataaggg cagccagcct atcaataata ggtagcttta aggaagcggc gataatagca
     8941 atagaggttc caatagaggt cacagcatca gaaagattat ctttagaggc tgcaaccaag
     9001 gcactggatc ttaccttttt tgataacgct ttattaaaag catatactcc aagcatcaca
     9061 agggctgaag cgatcccaac aatagcacct aatggatcga tagcagactg cttaccacta
     9121 atcatctgtt gaatagtttg caggagaacc tgaaagccaa caatgaacat gataaaggag
     9181 gttattaagc ttgaaaggtc ttcgattttc cagtggccaa agcggtgatt ggcgtctgct
     9241 ggctggctgg ccagatgaag tccgatgagc agagtgacat taccaacgat atcagacagg
     9301 ttgttgaagc catcggcaat caaggagctg gcatttaaaa gatagccagc aagaagcttt
     9361 gtgatgctaa gggccaaata ggtaacaatg ctaacaatgg gccctctttt tgctaaccga
     9421 aggttttcta ctggattgtt tggcataaaa actcctttgt aactgatgct ttcattatat
     9481 cataaaagct aagacaagct aaaagcctag agctatccta aatagggtat tccaggcttt
     9541 tcgatagctt atttggtgct ttggcgctta aaatatgccc ttgtctcaaa aatgacaaca
     9601 ggagataagg ctagtagggc gataagattt ggcagagcca tcaggccatt gacaatatct
     9661 gccagtatcc aaatcaactc cagcttaaga aagccaccaa gtcctaccat gataacaaag
     9721 atcaggcgaa aatagctgag gtgtgtcgtg ccaaataaaa agataaagca gcgctcacca
     9781 taatagctcc agccgagaat agtcgtaaaa gcaaaaagaa caagcgacag ggtcaaggca
     9841 taggtgccca tatgcccaaa gatagaagca aaggcagact gtgttaaggg tgctccctct
     9901 agtgcgctag tccactgacc agttaccaaa atggccagac cagtcagagt gcagatgatg
     9961 atcgtgtcaa taaaggttcc ggtcatagaa atcaggccct gttctactgg ctccttggtt
    10021 ttagcggcag cagcagcgat cggagcagag cctagtcctg attcgttaga aaaaacccca
    10081 cgtgcaatac ccttttgaat ggcgtcctta accaagcttc cggcaaagcc ccctatagct
    10141 gctgtagggg taatagcgga cttaaagata aggacaagca taggaagaag cttagtatag
    10201 tgaacagcaa taaccgttaa gcttgctcca atataaaaga tagccatgaa aggaacgact
    10261 gtttcagcca ccttggcaat agcttgaatg cctccaaaaa taatcatggc cacaacagca
    10321 gctagcaaga cactgattaa tggcgaagag atcccaaggc tatggtgtag ggatgaggta
    10381 atcgcattga cctgagcaaa tgtcccgatt ccaaacaaag ccactaaaat accagagaca
    10441 gcaaataagt tggctagagg cctccatttt tgccccatac catttaaaat gtagtacata
    10501 ggtccgcctg aaatctgacc attagcgtcc ttagtacggt atttaatggc taaaacgccc
    10561 tcggaatatt tggttgccat accaaagaag gcagcaaccc acatccaaaa aagtgcccca
    10621 ggtccaccag actttatagc ggttgcgaca ccaacaatat taccagtacc aactgtagca
    10681 gctagggctg ttgctagagc agcaaatgat gaaatatctc cttgcccctc attcttagca
    10741 aaaatgagcc taaaggcctt aggcaacttg atgacttgga gaaggctaag tctgctggtg
    10801 aggtaaatgc cagtaccaag cagcagtagc aacaagggtg ctccccaaac caaatcgtct
    10861 atccattttg cagcagctat catgcttaat tcctcaactc tcttaaccaa tgctgccaaa
    10921 agaaaaagcc acccctgcgg atagcctctg aagcatatga caaaacagca agcacaaaaa
    10981 atgctaagga agcatgatca tacggcttga tattttatct tctgtccttt tgcctgagag
    11041 attgagcagt cttgccttgc cccttcggcg cctaataggt ctctccagaa gcccgtccgt
    11101 caagcagtcc cgtccaacac ctgaacacct gagagtataa ctccttcggc gaaatccatt
    11161 cttctcctgc atgacatcat tcggtttatt aaattatgtc tatgataccc aaaaagccta
    11221 gtgatgtcaa caagcaattt aactgatggc taactccttg tttttatggt aacatcattg
    11281 tcctcttttt tctttttgac tgaaacatga tataatcgta aggttaataa aagtcactta
    11341 ttagacgata tgaggagaaa gcatgaatcc tttattagat ggaatgaatg ataaacaagc
    11401 agaggcagtt caaacgactg agggcccctt gttaattatg gctggtgccg gttctgggaa
    11461 aacgagggta ttaacccacc gcattgccta cttgattgat gaaaagtatg ttaatccctg
    11521 gaatattttg gcgattacct ttactaataa ggctgcgcgt gagatgcgag aaagggcatt
    11581 ggccttaagc ccagccacca aggatacctt gattgcgacc tttcactcaa tgtgtgttcg
    11641 tattttacgc cgtgaggcag atcatattgg ctacaatcgg aatttcacga ttgttgatcc
    11701 aggagaacag cggaccttaa tgaagagaat agtaaaagct ctaaatctgg atcctaagaa
    11761 atggagcgag cggtcgattt tagccaccat ttcaaatgct aaaaatgatc tcttagatga
    11821 aagagcctat gagctaggag cctctgattt gtatagccag acagttgccc gctgctacaa
    11881 ggcctatcag gaggagctca gacgaagtga ggctatggat tttgatgatt tgattatgat
    11941 gaccttacgc ctatttgatc aaaatcctga cgttctagcc tattatcagc agcgttatca
    12001 atatatacat gtcgatgaat accaagacac aaaccacgct caatatcagc tagtgactct
    12061 tttagcctca cgctttaaaa atatttgtgt tgtcggtgat gcagaccagt ccatttatgg
    12121 ctggcgtggt gctgatatgc aaaatatttt agattttgaa aaggattacc ctgatgcaag
    12181 ggtggttttg ctggaagaaa attatcgctc caccaagaaa atccttcagg cagctaacga
    12241 ggtgattcag cataatcgtc atcgtcgtcc gaaaaaattg tggactcaaa acgcagacgg
    12301 tgagcagatt gtttattata gggcaaatga tgagcgtgac gaggctgttt ttgttgcctc
    12361 aaccatcagc aatatgtgtc tagagctagg aaagagcttt aaagactttg ctgttttata
    12421 tcgtaccaat gctcagtccc gtacgattga agaagccttg ttaaaatcaa atattcccta
    12481 cacgatggtc ggaggaacca aattctacag cagaaaggaa attcgtgatg tgattgccta
    12541 tttgactgtg gttgctaatc cgtcagataa tctctccttt gaacgaattg tgaatgagcc
    12601 taaacgaggg gtagggccag gaaccctaga taagctccgc caatttgctt atgggcaagg
    12661 acagtcattg ttagaggccg cttcaagcct tgagcaatca ccgctaaaag gaaaggctgc
    12721 ccaagccatg ctggccttag cgagtctctt aagtgatttg agagctgatt tagaccagct
    12781 gagcattaca gccctggccg aggccttgct ggagaaaacc ggctatctgg atatgctgcg
    12841 cgtccaaaat accttagaaa gtcaagctag gattgaaaat attgaagaat tcctgtctgt
    12901 taccaaaagc tttgatgacc tatcagcaca gcagcaggag catgaagcag gtattgatcg
    12961 cttaggaaga tttctcaatg accttgcttt gattgctgat agtgatgatg gcaatgcaga
    13021 aaccgctgag gtaactttga tgactctgca tgcagctaag gggctagaat ttcctgttgt
    13081 ttttctcata ggtatggagg agggagtctt tcctttagcc cgagcagccg aggatcaaga
    13141 tgagctagaa gaagaaaggc gactagccta tgttggcatt accagagccg aggaatgctt
    13201 gtttttaacg aatgccaata cacgtaccct atttggtaaa agcagctata atcgcccaac
    13261 aaggttttta aaagagatgt cagagaacct tttaagcttc caaggcttgg caagacctgc
    13321 tcatgcttcc tttggtgtga cattttcgca gcagggtcaa cgacaatttg gcacaggaat
    13381 gagtctatca gaggctatcc agtccagaaa atcaatggca cagcctgcca gagcagcctc
    13441 aacatctaca ccgctgccct ttggaccgaa tgcagctact tcaaagcaag ccgttgattg
    13501 gcagattggt gatattgccc atcataaaaa atggggtgct ggaacggttt tagaggtcaa
    13561 gggatctggt aagaccatgg aattaaccat tagttttcct gatgtcggat taaaaaaact
    13621 ccttgccagc gttgctccta ttgaaaaaaa ataaaaggta cagcttatgg gcaatttgca
    13681 tagtcacttg gataagggct ttgcaattgc ggtttagttc tgcgatttaa gaaaagaagt
    13741 aagcaaggat tttatcagtt aaccacatac caagcttttg atggccttga tgccggagag
    13801 agcttggtat ttttttattt ttaaaaaaat cacaaaaaat gatttattct gagcataatc
    13861 cttgcaaatt aaaatgagaa gcgtataatg gcaatataaa ttaaataaca agtggtcact
    13921 tttgttaata gttgttttaa ggtatttgta gcgctt
//
LOCUS       DARYNN010000051        13609 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.051, whole genome shotgun sequence.
ACCESSION   DARYNN010000051 DARYNN010000000
VERSION     DARYNN010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13609)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13609)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13609
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.051"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            6..596
                     /locus_tag="TVB59_001605"
     CDS             6..596
                     /locus_tag="TVB59_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1010476.1"
                     /translation="MEGITKSYGAKLILKDFSYTFEQGKKYLIKGASGRGKSTLLHII
                     KGTAVDSGKIAFITKDNHSFESYQANIGMVSQAPFLFNGTLEENICLNQEFSKENILA
                     VLDQVHLLEELPAGLGFQIENNGTNISGGQRVRIELARFLLRQKDILLLDEVTAALDK
                     DNARRVRELIFSLPITIIEVAHHVDQAIAYDDMIEL"
     gene            606..2168
                     /locus_tag="TVB59_001606"
     CDS             606..2168
                     /locus_tag="TVB59_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1010477.1"
                     /translation="MFKYFNKYLVTLTLVACALNSLVFLIEPLITSKIFDLTFLNNHQ
                     DTLSFLGYGLTLYVVLYSVMFIANLLINHIMTIGCGRIRLRLYQNLILNYREMSHDKK
                     ISMLTQDVEYYLWNHISPSILLVSHVSNVLLLSAYLLSKNMLIGLIFIACAFVFLVVQ
                     HVIGQKAEQKGSELAVARQKLLGLLSDVVAGHSTLIQNQALFASLKQVKKQSEHYESS
                     RQAFEIFRSFFTLLAHLMLFISQFLPIFLGLALTLLGVKLRTTDLIAMFIAATRLEQP
                     LKNIVDDMFRLNGAKAIAKHFETLLEQPIPKYQSHAMTGDPFECLDGHHLAKSFAGRT
                     LFSDLSFHFEKGKKYLIKGSSGSGKSTLFKLILQEMSPDEGTLDMVLTGGQTTDNYHH
                     RIGLIAQSPYLFNDSIRYNLTLGEAFSDELLLEKLEQVGLTDEFDDILNHQIVNNGEN
                     ISGGQKTRLEIARSLIRQKDVLLADEVTAPLDVKNAKTIRQLLFSLPVTVIEIAHHID
                     DTFIYDGDIDLS"
     gene            2551..3652
                     /gene="prfB"
                     /locus_tag="TVB59_001607"
     CDS             join(2551..2622,2624..3652)
                     /gene="prfB"
                     /locus_tag="TVB59_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658142.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEL1010478.1"
                     /translation="MEVAEMRQQIVENKEKLTSFRRSLDLERLEEDIALLENKMTEPD
                     FWNDNMAAQKTSQELNELKLTYQTFHDMQELSDETELYLEMLDEDDSVKEELEASLIK
                     LSQMLASYEMTLLLSEPYDHSNAILEIHPGSGGTEAQDWADMLFRMYTRFGNAKGFKV
                     ETLDYQAGDEAGIKSVTLSIEGPNAYGFLKSEMGVHRLVRISPFDSAKRRHTSFVSVE
                     VMPELDDTIEVEIRDDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVASTVDRT
                     QYGNRDRAMKMLQAKLYQLEQEKKAEEVNALKGDKKEITWGSQIRSYVFTPYTMVKDH
                     RTNFEVAQVDKVMDGDIEGFIDAYLKWRMGED"
     gene            3703..4395
                     /gene="ftsE"
                     /locus_tag="TVB59_001608"
     CDS             3703..4395
                     /gene="ftsE"
                     /locus_tag="TVB59_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEL1010479.1"
                     /translation="MALIEMKGVSKKYRRSTTALRDINVSVNQGEFVYIVGPSGAGKS
                     TFIKLLYREEKLSSGSLKVGEFDLTKLRGREVPILRRSIGVVFQDYKLLPKKTVFENV
                     AYAMEVIGERRRHIKKRVPEVLDLVGLKHKMRSFPNQLSGGEQQRVAIARAIVNNPKL
                     LIADEPTGNLDPEISWEIMHLLERINLQGTTILMATHNSHIVNTLRHRVVAIENGRIV
                     RDEEKGDYGYDD"
     gene            4388..5317
                     /locus_tag="TVB59_001609"
     CDS             4388..5317
                     /locus_tag="TVB59_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1010480.1"
                     /translation="MIRHFFRHIWESIKNLRRNLLMTFASVSMVTVTLTLLGVFAATL
                     LNIQRVASGVENNIQINAYLQVDSTDAAKMVQSINGEQINNENYHKIYDQIAGLKGVE
                     RIIFSSKDEQLQKLQDSLGDVWGMYNEDSNPLQDIYIVETKTPKQVKSVTKAIKKIQG
                     IEDADYGGINSDKLFKFSKLIQTWGIIGTLLLLFIAIFLISNTIRMTIMSRQRDIAIM
                     RLVGAKNSYIRGPFFFEGAWVGLFGAILPSLIIYYGYEFAYKHFTPELQHNSLSMYPI
                     NPYVYYLIGMLFVIGIIIGSLGSVLSMRRYLKF"
     gene            complement(5707..6348)
                     /locus_tag="TVB59_001610"
     CDS             complement(5707..6348)
                     /locus_tag="TVB59_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEL1010481.1"
                     /translation="MTIMTLMNPVAGENTYLLVNDEAILVIDPGSKGQAILSQIHAIN
                     KPVAAILLTHTHYDHIMSLELVRESCQHPPVYVAKEEADWLYKPEMNLSGLIRHADLP
                     DIICKPAEKLFQYQTPYQLAGFHFSVVPTPGHSAGGVSFIFEQEEAVFTGDALFRESI
                     GRTDLPTGNLEQLLASIRDKLLTLPNHYQIYPGHGSATTISHEKNSNPFLRQR"
     gene            6685..9156
                     /locus_tag="TVB59_001611"
     CDS             6685..9156
                     /locus_tag="TVB59_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEL1010482.1"
                     /translation="MINEFSQKYAVIDLEATSPGPTASIIQVGIVIVEGKEIVDSYQT
                     DINPHEPLSDHIKALTGITDQQLAQAPDFSQVARTIFELIEDCVFVAHNVTFDANLLA
                     EALFLEGYDLLTPRVDTVELAQIFYPSLEKYSLSHLSEVLDLNLSDAHTAIADAQATA
                     NLFIKLLHKIESLPRECLETLLLYADSLLYETAMIVRQALAVSRPYSTSDYIKINQIL
                     LKKPDQLTKPYQLSQSFEINAALLGLEERPKQLSFAKIVEETLFQTEPAFIEAQAGIG
                     KTYGYLLPLLAQKHQTQILVSVPTKLLQDQIMANEVRAIQEQFHIDCHSIKGPANYIK
                     LDSFQESLNQLDDNRLVNRYKMQLLVWLLETRTGDLDEIKQKQRFAAYFDQIKHDGSI
                     QQTSPFYAYDFWQQSYQRAKSARLLITNHAYFLHRIQDDKAFAKGKILVFDEAQALML
                     QLEELAHQRLNIADTLQELQEQLAVPSSLLEQRLLEGIAFELNQLSSHYHQEEEKQQA
                     QASQHLLRLQEHVKELGAAASQSLKQLFKQQEMDYWVSSEQQADKRQTFLNGSSRTVL
                     QFKALLPEIFKAYFVSATLQISPSISLADLLGFDTYSYHQLAKEKSTQQLVVIDQDMP
                     LIKDLTDEAYTQTIAARLLVLHQQQQVPILVLFNAKKHMLMVSDYLEANQVQHLTQGK
                     NGTAYHIKKRFDRGEQSMLLGLAAFWEGVDFVHADRMIEVITRLPFDNPEDIATQKMQ
                     RYLQAAGKQPFNDYFLPMTILRLKQAIGRTLRRKEQKSAVLILDRRILTMSYGQTILH
                     SLEEEFLISQQNFQDSLAEIGDFLI"
     gene            complement(9330..10496)
                     /locus_tag="TVB59_001612"
     CDS             complement(9330..10496)
                     /locus_tag="TVB59_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEL1010483.1"
                     /translation="MKYNKTKYPNIFTYDTKKGKRYYVRRGYYLKGKKKEATKSNLKT
                     LQEARAALTEIEQKIENNDFAYNKNLTVDQYWNMYVDNRLKTGSWKPDTEANKEAIYK
                     THFKKYLGKTKMKDISRIEYENHINGMRKNYSKNTLRLIHSVLNAMLNHAVTNKMLDD
                     NPIDGITIGDSEIIPVNKRISLEEFKEWDSWAKKSLIQYDYTIVRMTYFGARSSEVVA
                     IKIGNLTKLENGRYRILLDESRTYHRPNGGGMKTPGSERFMEVDLETSHYIDDVVVES
                     KRIAKKYNRILSKEDYLFLTNFKNAKKELLGMPISIRRVYKLFNTVNEKSGMHVTPHM
                     MRHFFATQGQIAGVPIEHMAAALGHSTSYMTSKYTHIKEEVAGSVTDRFMSALN"
     gene            complement(10672..10938)
                     /locus_tag="TVB59_001613"
     CDS             complement(10672..10938)
                     /locus_tag="TVB59_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010484.1"
                     /translation="MSQEIYSKSEIDLKFENLETKIDSKFDLLMQKMDDGFEKQRLNT
                     EKMLSDFKLNLVTDQQKNKKEFMYWAIGIIIALAGIAFPIWFGK"
     gene            complement(11040..11465)
                     /locus_tag="TVB59_001614"
     CDS             complement(11040..11465)
                     /locus_tag="TVB59_001614"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010485.1"
                     /translation="METEKINNVNILRSNNSRLSGYATSASYPLILPIIVEFELYNIK
                     QSKTYLFQITATKINDRRQNNHIKDLLSLSSNQTTVTISAERHNTFFPYEGYGTVATK
                     LDFSFNIDSPGDYCIALTLLDSEGSLLDKHSNYYIFGEE"
     gene            complement(11531..11857)
                     /locus_tag="TVB59_001615"
     CDS             complement(11531..11857)
                     /locus_tag="TVB59_001615"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010486.1"
                     /translation="MYFDEFKEYVENNSRAHDYFFERALDYQNAKNARRTPAHRRWKE
                     QKVLKEVETMWTNVVKQLYDNIKLNGKFRKRFMHQEEIDEWVSFMNEHEILESFADSM
                     AEIEFE"
     gene            complement(11870..12157)
                     /locus_tag="TVB59_001616"
     CDS             complement(11870..12157)
                     /locus_tag="TVB59_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEL1010487.1"
                     /translation="MYKIEFDPKVKKQLKKLDKTASSKIIRWLYANVDGTSLPRLHGK
                     ALTGDLAGLWRYRIGDYRVICDIQDDKLVILAVHIAHRKQVYKLKLPNNKR"
     gene            complement(12157..12387)
                     /locus_tag="TVB59_001617"
     CDS             complement(12157..12387)
                     /locus_tag="TVB59_001617"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010488.1"
                     /translation="MTTFTLTIDEKNKYIADYFKRNNIDDSQLTFEQLLTVLEDAEDY
                     AAGMAVLMEQKDNPDYKTYTLQEVADELGITL"
     gene            complement(12401..13168)
                     /locus_tag="TVB59_001618"
     CDS             complement(12401..13168)
                     /locus_tag="TVB59_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1010489.1"
                     /translation="MSERNLRQVDILEKSKPFQKQLGVKMGRSTLSQYVSGKSVPAQR
                     QLYLLSKTLNVSEAWLMGYDVAIERIPDEKRRATTEISNQPEIVSIYNQLEQPRQEKV
                     LSFANEQLEEQNKVVSTHEELFSVQGVTYAAAASGFGRGFEADEYDTYTVYTDEEPPR
                     YDYAIGIRGDSMLPKYEQGDMLYIVDRGMSTYNGQLCIVVHNGQTYFKKVYTEEDGLR
                     LVSLNKKYNDIFIDYPPAEDTYIKIYDVVGSFTPVEM"
     gene            13376..13609
                     /locus_tag="TVB59_001619"
     CDS             13376..13609
                     /locus_tag="TVB59_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF739 family protein"
                     /protein_id="HEL1010490.1"
                     /translation="MVFDYSKLSGRIVEKFGTQYNFALALGLSERSLSLKLNNKVDWR
                     SKEIAQACQELDINENDVGEYFFKQNVHIHEQN"
BASE COUNT         3842 a         2638 c         2848 g         4281 t
ORIGIN      
        1 tggctttgga agggatcaca aagtcctatg gcgccaagct gatccttaag gatttttcct
       61 atacctttga acaggggaaa aaatatttga taaagggtgc cagtggtaga ggtaagtcga
      121 ctctgttaca cattattaag ggaactgctg ttgactcagg taaaatagcg tttatcacca
      181 aagacaatca ctcatttgaa agctatcaag ctaacattgg catggtgagt caggcacctt
      241 ttctctttaa tggcaccttg gaagagaata tctgtctgaa tcaggagttt tccaaggaga
      301 atatccttgc tgtcttggac caagttcacc tgttggagga attaccagct ggtctaggct
      361 ttcagataga aaataatggg accaacattt cgggcggcca gcgagtgcgc atagaattgg
      421 ctcgattttt gctacgtcag aaggatattt tattgcttga tgaggtcaca gcagccttgg
      481 acaaggacaa tgctcggcga gtaagggagc tgattttttc tcttcctatt accatcattg
      541 aggtggctca tcatgtggat caagctatag cttatgatga tatgatagaa ttgtaggtga
      601 ttaagatgtt taagtatttt aataaatatc tagtgacact aacgcttgtt gcatgtgcct
      661 taaacagtct tgtctttctg attgaaccct tgatcactag taagattttt gatttaacgt
      721 tcttaaataa tcatcaagac accttgtcct ttttaggcta tggtctgacc ttatacgtgg
      781 tcttatattc tgttatgttc attgctaatc ttctgatcaa ccatatcatg acgattgggt
      841 gtggtagaat caggttgcgt ctctatcaga atttaatctt aaattatcgg gagatgagtc
      901 atgacaagaa aatttctatg ctgactcaag atgtagaata ttatctatgg aatcacatca
      961 gccctagcat tcttctcgta tcacacgtga gtaatgtcct tttgctcagt gcttacctgt
     1021 tatcaaaaaa catgctaatt ggtcttattt ttattgcatg tgcttttgta tttttagtgg
     1081 ttcagcatgt gattggtcaa aaggcagagc aaaaaggtag tgagctggca gtagcgagac
     1141 aaaagctgct tggcttatta agtgatgtgg ttgcggggca ttcgacatta attcaaaatc
     1201 aagctctttt tgctagcctc aaacaggtaa aaaaacagtc agagcattat gagagctcac
     1261 gtcaagcatt tgagatattt aggtctttct ttaccctatt ggcacatctg atgctgttta
     1321 tttctcaatt cttgcccatt tttttaggct tagccttaac cttattaggt gttaagctga
     1381 gaacaactga tcttattgcc atgtttattg cagcaacgcg cttagaacag ccactcaaaa
     1441 atattgttga tgatatgttt aggcttaatg gtgcaaaagc cattgctaag cattttgaga
     1501 cacttttaga gcagcctatt ccaaaatacc agtcgcatgc tatgacaggt gatccttttg
     1561 aatgcttaga tggtcatcat ctggcgaaat catttgcagg taggacctta ttttccgatc
     1621 tctcttttca ttttgagaag ggaaagaaat acctgattaa gggatcaagt ggatctggta
     1681 aatccacact ctttaagctt atcttacagg agatgagtcc tgatgagggg acactagata
     1741 tggtattgac tggaggtcag acgactgata attatcacca tcgcataggg ctgattgcgc
     1801 agtcgcctta tctttttaac gatagcattc ggtataattt gaccttgggg gaggcgtttt
     1861 ctgatgagtt gcttttagaa aagctagaac aggttggctt gactgatgaa tttgacgata
     1921 ttttaaacca ccaaattgtt aataacggag aaaatatctc aggtggtcaa aagacacgtc
     1981 ttgaaatcgc aagaagcctc attagacaaa aagatgttct tctagcagat gaagtgacgg
     2041 ctccacttga tgtcaaaaat gctaaaacta tccgacagct actatttagt ttaccggtaa
     2101 cagttattga aattgctcat catattgatg acacctttat ctatgacggt gatattgatt
     2161 tatcgtagaa aatatcatca cattgcttag aaataataat tgatgcttat gaaattgtca
     2221 ttcacacagt gaatggcttt ttcttaggct aaattttcca tgtggagctt gatctgatag
     2281 gctatctgag aaaaaaagct aacaacagcc atgttttttg gggctatgac tgttctaata
     2341 cgagctgcct ctagctgctg gtatataaga ggtgacatga ttgtcacaat tcgtcatcat
     2401 tttgtcgtta aatttttaca tagatttctt atgctagtca tggcagagct ccttacccta
     2461 aaaagaaggg aatttagctg atgggaaata gcaattctaa agcctttatg ataaaatgaa
     2521 aaaagacact ataatagaag aggtaactgt atggaagtgg cagaaatgcg ccagcaaata
     2581 gtagaaaaca aagagaagtt gactagcttc aggaggtctc tttgacttag agcgtttgga
     2641 ggaggatata gctctcttag aaaataagat gacagagcct gatttttgga atgataatat
     2701 ggcagctcaa aaaacctctc aggaattaaa cgagctcaag ctcacctatc aaacctttca
     2761 tgatatgcag gagctatctg atgagacaga gctttattta gaaatgcttg acgaggacga
     2821 tagcgtcaag gaagagctag aagcaagcct gattaagctc agccagatgc tagcaagcta
     2881 tgaaatgacg ctgcttttgt ctgagcccta tgatcatagc aatgcaatcc tagaaattca
     2941 cccaggttca ggtggcactg aagcacaaga ctgggcagac atgctttttc gcatgtacac
     3001 tcgctttgga aatgccaagg gctttaaggt agaaactctg gactatcaag caggagacga
     3061 ggcaggaatt aagtctgtga ccctttctat tgaagggcca aatgcttatg gcttcttaaa
     3121 atcagaaatg ggagtacatc gtctggtgcg tatttctcct tttgactctg ctaagcgtcg
     3181 tcacacctcc tttgtttcag ttgaagtcat gccagagctt gatgatacca tcgaggtgga
     3241 gatacgtgat gatgacatta agatggacac cttccgctca ggtggtgctg gtgggcaaaa
     3301 tgtcaacaag gtctcaactg gggtacgctt gacccatatc ccaacaggaa tcgtagtggc
     3361 gtcaacagtt gaccgcaccc aatatggcaa ccgtgatcgc gctatgaaaa tgcttcaagc
     3421 caagctttat cagttagagc aggagaaaaa ggcagaagag gtcaatgccc tcaaggggga
     3481 taaaaaggag atcacctggg gcagtcagat caggtcctat gtctttacgc cttatacgat
     3541 ggtgaaggat catcgtacca attttgaggt ggctcaggtt gataaggtga tggacggaga
     3601 tattgagggt tttattgacg cttatctcaa atggcgcatg ggtgaggatt aaagtgatcc
     3661 ccactcagat aaacactaac agcttagaga aggaagaata agatggcatt aattgaaatg
     3721 aagggtgttt ctaagaaata ccgtcgctcg acaacagctc tgagagacat taatgtctca
     3781 gtcaatcaag gggaatttgt ctatattgtt ggtccatcag gagctggtaa atcaaccttt
     3841 atcaagcttc tttatcgcga agaaaagcta agctcaggca gcctaaaggt gggtgagttt
     3901 gacttaacca agctaagagg acgtgaggtt ccaattttac gtcgcagcat tggtgttgtt
     3961 tttcaggatt ataagttgct ccctaaaaaa acggtctttg aaaatgttgc ctatgctatg
     4021 gaggttatcg gagagagacg tcgccatatc aaaaagcgtg ttcctgaggt tctagacctt
     4081 gtcgggttaa agcataagat gcgctccttt cccaatcaat tgtcaggtgg tgagcagcag
     4141 cgtgttgcga ttgcacgcgc tattgtgaac aatcccaagc tcctcattgc agatgagcct
     4201 acaggcaatt tggatccgga aatttcttgg gaaatcatgc acctgcttga gcgtatcaat
     4261 ctacagggga caacgatatt aatggcaacg cataacagtc atatcgttaa tactcttcgc
     4321 catcgcgtgg ttgcgattga aaatgggcgt attgtccgcg atgaggagaa aggagactat
     4381 ggttacgatg attagacatt ttttccgtca tatctgggaa tctatcaaaa atttaaggcg
     4441 taatctcctc atgacctttg cgtcagtcag tatggtgacc gtcaccttaa ccctgcttgg
     4501 ggtctttgct gcaaccctgc tgaacattca acgtgtcgct tctggcgtgg aaaacaacat
     4561 tcaaatcaat gcttacttac aggttgattc gacagatgct gctaagatgg ttcagtcgat
     4621 taatggagag cagataaata acgagaatta ccataagatt tatgatcaga ttgcagggct
     4681 aaagggtgtt gagaggatta ttttctcaag caaggacgag cagctgcaaa agctacagga
     4741 tagtctgggc gatgtctggg gcatgtataa tgaggatagt aatcctctgc aagacatcta
     4801 tatcgtagag accaagaccc ctaagcaggt caaatcagtt accaaggcca tcaaaaagat
     4861 tcaagggatt gaagatgcgg actatggtgg tattaattct gataagcttt ttaagttttc
     4921 aaaactgatt caaacatggg ggattatcgg aacgctgttg ctcctgttta ttgcgatctt
     4981 tctgatttca aataccattc gcatgaccat catgtctcgt cagcgcgata ttgcgatcat
     5041 gcgtctggtt ggtgcgaaaa attcttatat tcgtggccca ttcttttttg aaggggcttg
     5101 ggttggtctg tttggtgcga tattgccatc gttgattatt tattatggct acgagtttgc
     5161 ctacaagcat ttcaccccgg aattacagca taatagcctg tctatgtacc ctatcaatcc
     5221 atatgtttat tatttaattg gcatgctttt tgtgattggt attatcattg ggtcactagg
     5281 atcagtctta tctatgagac gttaccttaa gttttaattg aaagagcttc tagcctgtgt
     5341 gcctggactg gtaccctgcg gttagggctc tttttgcttt tggggcaatg cttgctagat
     5401 aagcaaacaa tagcttaagc ccataccatt aagtattggg cttaagctat tgttatagtt
     5461 gtttaggtaa tagaagcagc cggaacttga ggtgtcctat ctaggtcttg agctatagct
     5521 tttctggcta gttggtgttt cttcacgtaa cagcgatttg tcgaacgata aggtgctctt
     5581 cttgtgatag ctggcttgta gtgatcgaca ggtgctaagt caaattagcc atcctgatgg
     5641 actggagtca tagcttttgc tgctgcgcct ggttgggcat agactgggca tctcggtagc
     5701 ttgagcttat cgctgcctca gaaagggatt gctatttttt tcatggctaa tggtggtagc
     5761 tgagccatgc cccggataaa tctgataatg gttaggaagt gttagcagct tatcacgaat
     5821 gctagcaagc agctgttcaa gatttccagt cggcaaatct gttctaccga tgctttctct
     5881 aaacagagca tcgccagtaa acaccgcctc ctcctgctca aagataaagg aaacgccacc
     5941 ggcagagtgt cctggtgttg gcactactga aaagtgaaat ccagctagct gataaggtgt
     6001 ctgatactga aagagctttt ctgctggttt gcagatgata tcaggcagat cagcgtgacg
     6061 tatcagtcct gacaggttca tttctggttt ataaagccag tccgcctcct ccttggcaac
     6121 atagacagga gggtgctggc agctctctct caccagctct aggctcataa tgtgatcata
     6181 atgcgtatgg gtcagtagga tagcagcaac aggcttgttg atggcatgga tttgtgataa
     6241 aatagcctgc cccttgcttc ctgggtcaat gactaaaata gcctcgtcat tgacaagaag
     6301 gtaagtgttt tcacccgcaa cgggattcat cagtgtcata atagtcatac ccttagttta
     6361 ccaaaatctg actcaaaaga cagctcaaaa ccacctcttt tgataaaagt gatctgttta
     6421 atggttttga tggctaagcc aagatagctc cagcttaaag gctgcttttt ttaattaata
     6481 ggagcaaaaa ggagctgcct cagcgctaac agctaatcag agtattagct ctctagtgtc
     6541 atagcaagga agtaggctgg ggcgattaaa aggcttgata actagctttt tatgatactg
     6601 actagcccta ttgagctgag ctaagactgg tattgtcaga tttaggcaaa gcctgtcaga
     6661 aaacgtgcta taatagatag tactatgatc aatgagtttt cacaaaaata tgctgtgatt
     6721 gacctggaag ccactagccc aggtccaaca gcgtctatta ttcaggttgg cattgtgatc
     6781 gttgaaggaa aagaaatcgt tgattcgtat caaactgata ttaatcctca tgagcccttg
     6841 tcagaccata tcaaagcact cacaggtatt acagaccagc agctagctca ggcaccggat
     6901 ttttcacagg tagcaaggac catttttgag ctgattgagg actgtgtttt tgttgctcat
     6961 aatgtcacct ttgacgccaa tttgttggca gaagccttat ttttggaggg ctatgatctc
     7021 ctcactccta gagtggatac tgttgagctg gctcagattt tttaccccag cctagaaaaa
     7081 tacagcctta gccacctatc agaggtgcta gacctaaacc tatctgatgc tcataccgct
     7141 attgctgatg ctcaggcgac tgctaactta tttatcaagc tgcttcacaa gatagagagc
     7201 ttgccaagag aatgcttgga gactcttttg ctgtatgctg atagtctgtt atatgagaca
     7261 gctatgattg tgagacaagc ccttgcagtc agtcggcctt attctacgag tgactacatc
     7321 aagattaatc agatcttgct aaaaaagccg gatcagctaa caaagcccta tcaattatcc
     7381 cagtcctttg agattaatgc agccctctta ggtcttgagg agcgccccaa gcagctcagc
     7441 tttgcaaaga ttgttgagga gactcttttt cagaccgagc cagcctttat cgaggctcag
     7501 gcaggcattg gtaaaaccta tggctattta ctgcctctcc ttgcacagaa acatcagacc
     7561 caaatcttgg ttagtgtgcc aaccaagctg ctacaggacc aaatcatggc taatgaggtg
     7621 agggctattc aggagcagtt tcacatcgat tgccatagta tcaaggggcc tgctaattac
     7681 atcaagctag acagctttca agagagcctc aatcagcttg atgacaaccg cttggttaat
     7741 cgctataaaa tgcaattgct ggtttggctt ttggaaacaa ggactggtga tttagatgaa
     7801 atcaagcaaa agcaacggtt tgcagcttac tttgaccaga tcaagcatga tggcagtatc
     7861 cagcagacct cgccctttta cgcttatgat ttttggcaac aaagctatca aagggctaag
     7921 tcagctcgct tgctgatcac caatcatgcc tattttttac accggattca ggacgataag
     7981 gcatttgcca agggtaagat tctagtcttt gatgaagctc aggccttaat gctgcagcta
     8041 gaggagctag ctcatcagcg actaaatata gctgatacgc tccaagagct tcaagagcag
     8101 ctagctgtgc caagcagctt gcttgagcaa cgcttgctag agggcattgc ctttgagctc
     8161 aatcagttaa gcagtcatta tcatcaggag gaggagaagc agcaagctca agcctcacag
     8221 catttgctgc ggctccaaga gcatgtcaag gagctaggtg ctgcagcctc tcagagcctc
     8281 aagcagctgt tcaagcagca ggaaatggat tattgggtga gcagtgagca gcaggctgac
     8341 aagcgccaaa cctttttaaa tggcagcagc aggacggtcc ttcagtttaa agcattgcta
     8401 ccggagattt ttaaggccta ctttgtctca gctactctac agattagccc tagcattagc
     8461 ttggctgatt tattgggctt tgacacttat tcttatcatc agctggctaa ggagaaaagc
     8521 actcagcaat tggttgtcat tgaccaagac atgcccttga ttaaggactt gactgacgag
     8581 gcttacacac agaccatagc agcaaggcta ttagtgcttc atcagcaaca gcaggtacct
     8641 atcttagtgc tctttaatgc taaaaagcac atgctcatgg tttctgacta tttagaggct
     8701 aatcaggtgc agcacttgac acaaggcaaa aacggtacag cctatcacat caaaaagcgc
     8761 tttgatcgtg gtgagcaatc aatgctgctg gggcttgcag ccttttggga gggagttgac
     8821 tttgttcatg ctgatcgcat gatagaggtc attacccgcc tgccctttga taatccagaa
     8881 gatattgcca ctcaaaaaat gcagcgctac ctacaggcag caggtaagca gccctttaat
     8941 gattattttc tgccgatgac gatcttaaga ttaaagcagg cgattggtcg aaccctgcgt
     9001 cgaaaagagc agaaatcagc agttttgatc ttagatcgtc gcattctgac catgtcctat
     9061 ggtcagacca ttttgcacag cctagaagag gaatttctga tatcacaaca aaatttccaa
     9121 gatagtctag cagaaatagg cgattttttg atataatgaa aaatagtaat ttttatttag
     9181 ttattttaat ttatttattt tgcaaatgtt tatttatagg catttgcttt tttgtttaat
     9241 tgataccaaa taataaaaat ctataaattg tcggggaata tatcggggga tttgttaatt
     9301 taagcatttg tataaatttc cccgactaac tagtttaaag cgctcataaa tctatcagta
     9361 acactaccag caacctcctc ctttatgtga gtatatttgc tagtcatgta acttgtagaa
     9421 tgacctagtg ctgcggccat atgttcaatt gggacacctg ctatctgccc ttgggtggcg
     9481 aaaaagtggc gcatcatgtg tggggtaaca tgcataccag atttttcatt gacagtatta
     9541 aaaagtttat agactcgcct aatagagatc ggcattccta aaagttcttt tttcgcattc
     9601 ttaaagttag tcaaaaatag gtaatcctct tttgataata tacgattata cttctttgca
     9661 atccttttag actcaacaac aacatcatca atataatgcg atgtttcaag atcaacttcc
     9721 ataaaccgct ctgatcctgg cgttttcatt cctccaccgt ttggacgatg gtacgtccta
     9781 gactcatcta gcaatattcg atatctacca ttttcaagct ttgttaaatt gccaattttt
     9841 atggcaacaa cttcgctact acgagctccg aagtaagtca tacggacaat agtataatca
     9901 tattgaatca atgacttctt ggcccatgaa tcccactctt tgaattcttc aagcgatatt
     9961 cttttgttaa cgggtataat ctcactatcg ccaatagtta tcccatcaat tggattgtca
    10021 tctagcattt tattggtgac tgcatgatta agcattgcgt tgagtactga atggatcaag
    10081 cgtaaagtgt tctttgaata attcttacgc ataccattaa tatgattttc atactcaatt
    10141 ctagaaatat ctttcatttt agtcttgcct aaatattttt tgaagtgagt tttgtatata
    10201 gcttctttat ttgcttcggt atcaggtttc catgatccgg tctttaggcg attatctaca
    10261 tacatattcc agtactgatc aactgtcaaa tttttgttat aagcaaaatc attgttttct
    10321 attttttgct caatttcagt aagtgcagct ctggcttcct gtagcgtttt taagttgctt
    10381 tttgtagcct ctttcttttt accttttaag taataacccc tacggacgta gtagcgttta
    10441 cctttctttg tatcgtaggt aaagatattt gggtattttg ttttgttgta tttcattctt
    10501 aaatcctttc gttttttgac ttttggacga ggtcgtttga aaggatattg gcatcaccac
    10561 ctttgtgtga tataatttta ggtacaagaa aacgaccttt ttaatggttg tttcttatac
    10621 ggtttcgcct cacgctcaga gtcgccaaac tttgagagcg tggggctttt tttatttccc
    10681 gaaccaaatc ggaaaagcaa tacctgctaa ggcaataata ataccgatag cccaatacat
    10741 aaattctttt ttatttttct gttgatcagt cactagattt agcttgaaat ctgacaacat
    10801 tttttctgta tttaatcgtt gtttttcaaa accatcatcc attttctgca tcaataaatc
    10861 gaatttgcta tcaattttcg tttcaagatt ttcaaacttc aaatctattt ctgatttgct
    10921 ataaatttct tgtgacataa tagattcctc ctgactcttt tctaagtcta ttataccatt
    10981 atttttggca tcaatgttgg aggtttcggg tttatatagt gtaagatatt cactcataat
    11041 tactcttctc caaaaatgta ataatttgag tgcttatcta ataaagatcc ctcgctatcc
    11101 aaaagtgtaa gcgcaatgca atagtcaccc ggactgtcta tgttaaacga gaaatcaagt
    11161 tttgttgcca ctgttccgta tccttcatac ggaaaaaatg tattatgtct ctctgcggag
    11221 atggtgacag tagtctgatt gctggatagt gatagtaagt ctttgatatg attattttgt
    11281 cttctatcgt ttattttagt tgctgttatt tgaaatagat aggttttgct ttgcttaata
    11341 ttatacaatt caaactcaac tataatgggc aatataaggg gataactcgc acttgttgcg
    11401 tatcccgaaa gtcttgagtt attacttcgt aaaatattta cattatttat tttttcagtt
    11461 tccatgctta tctccttaac taattaaaaa ctctaattct tctttgatca acgctccgtt
    11521 agcgacgttc ctactcaaac tctatttcag ccatgctatc tgcgaatgat tccaaaattt
    11581 catgttcgtt catgaaggaa acccactcat caatttcttc ttggtgcatg aaccgtttcc
    11641 tgaacttccc gtttaacttg atgttgtcat aaagttgctt gacaacattg gtccacatag
    11701 tctcaacttc tttgagtacc ttttgctctt tccatcgcct atgagcgggt gttcgcctag
    11761 catttttagc attttgataa tcaagtgccc tttcaaagaa ataatcatga gcacggctat
    11821 tgttttctac atactcttta aattcgtcaa aatacattac tttaaacctc tatcgtttat
    11881 tgtttggcaa tttgagtttg taaacttgct ttctatgggc tatgtgaaca gctaggataa
    11941 caagtttatc atcttgtata tcacagatga ccctataatc tcctatacgg tagcgccata
    12001 atccagctag gtcaccagtt aacgcttttc cgtgcagtct aggtagagaa gtaccgtcca
    12061 cattagcata aagccaacgg ataatttttg aagatgccgt tttatctaat ttttttagct
    12121 gctttttgac tttagggtcg aattctattt tgtacatcat agagtaatac ccaattcgtc
    12181 agctacttct tgaagtgtgt aggttttata gtcgggattg tctttttgtt ccatcaacac
    12241 tgccatacct gccgcatagt cttctgcatc ttctaggaca gtaaggagct gctcgaacgt
    12301 gagctgacta tcatcaatat tatttctctt gaagtagtca gctatgtatt tatttttttc
    12361 atcaatcgta agtgtaaatg ttgtcacaat atctcctcct ttacatttct acgggtgtaa
    12421 aactgccgac aacgtcatag attttgatat aagtatcttc tgctggtggg tagtcaataa
    12481 aaatatcgtt atatttcttg ttgagagata ctaatctaag tccgtcttct tctgtatata
    12541 ctttcttaaa ataggtttgt ccgttgtgaa caacgataca cagttgaccg ttatatgttg
    12601 acatacctct atctacaata tagagcatat ccccttgctc atattttggt agcatgctgt
    12661 ctcctcgaat tccaatagcg tagtcgtagc gaggaggttc ttcgtcagtg tagacagtat
    12721 atgtgtcata ttcatctgct tcaaatccac gaccaaagcc acttgcggct gccgcgtaag
    12781 ttacgccttg aaccgaaaat aattcttcat gcgtagaaac aactttattt tgttcttcca
    12841 attgttcgtt agcgaagctg aggacttttt cttgtctagg ttgttctagt tggttgtaga
    12901 tggacactat ttcaggttga ttagatattt ctgtcgtagc tctacgtttt tcatcaggta
    12961 tgcgctctat ggctacatca tatcccatca gccatgcctc gcttacgtta agggttttag
    13021 ataaaagata gagttgtcgt tgagctggaa cagatttgcc actaacgtat tgcgaaagag
    13081 tacttctgcc catctttacc cccaattgtt tctgaaaagg ttttgatttt tctaaaatat
    13141 caacctgcct taaatttctt tctgacatca gttgttttaa tctatttgaa gtagaactac
    13201 attgcataaa agtagattcc tttcgatgtt tataggttaa ttataaaaca tcttgaacaa
    13261 aagttcaata aaaaaattca aaaaaatgaa ctttgtgtat tgacaaagtt caaaacaaag
    13321 tgtaacataa aagcataaag ttcatgaaca tgaacaaaaa agaaaggagg ttcctatggt
    13381 ttttgattat tcaaaactca gcggaaggat cgttgagaag ttcggcacac agtacaactt
    13441 tgccttggct ttagggctat ctgagcgctc gctatcttta aaacttaata ataaagtaga
    13501 ctggagaagc aaagaaattg cgcaagcttg tcaagagtta gatatcaacg aaaacgatgt
    13561 aggagaatat ttttttaagc aaaatgttca tattcatgaa caaaactaa
//
LOCUS       DARYNN010000052        13213 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.052, whole genome shotgun sequence.
ACCESSION   DARYNN010000052 DARYNN010000000
VERSION     DARYNN010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13213)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13213)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13213
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.052"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(241..489)
                     /locus_tag="TVB59_001620"
     CDS             complement(241..489)
                     /locus_tag="TVB59_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEL1010491.1"
                     /translation="MEVKTLANIKSAIKRAELNVKANEKNSAQKSAMRTAIKAFEANP
                     SEELFRAASSSIDKAQSKGLIHKNKASRDKARLAAKLS"
     gene            complement(543..1463)
                     /locus_tag="TVB59_001621"
     CDS             complement(543..1463)
                     /locus_tag="TVB59_001621"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEL1010492.1"
                     /translation="MSNEFITFEKISRKSWKQLHQKSKPLLTQEELTSITSLNDNIDI
                     NDVVEVYLPLIHLIQVYKIAQENLSFSKSLFLKKDIQQRPFIIGISGSVAVGKSTTSR
                     LLQLLLARTHKTSTVELVTTDGFLYPNSTLIKNNMLNRKGFPESYNMELLLNFLDTVK
                     GGQTASAPVYSHEIYDIVPDQQQTFTNPDFLIIEGINVFQNQQNNRLYMSDYFDFSIY
                     IDADSHHIEQWYLERFLSLLELAKHDPANYYTRYTSLPQNEAIAFAKKVWKTINLENL
                     EKFIEPTRNRAELILHKAADHKIDEIYLKK"
     gene            1697..2326
                     /locus_tag="TVB59_001622"
     CDS             1697..2326
                     /locus_tag="TVB59_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL1010493.1"
                     /translation="MKKHRKKIGKHMTKMYYDENPDSAHDIHQLTVNLLGQSFTFLTD
                     SGVFSKRMVDFGSQVLLNTLDFQEGDRLLDLGCGYGPLGLSLAKAQGVEATLVDINHR
                     AVGLAKQNAESNQVEATIFQSNLYDGVTGTFEHIISNPPIRAGKKVVHEIIEKSIDFL
                     TKGGDLTVVIQKKQGAPSAKDKMEAVFGNVTILKREKGYYILRSIKERN"
     gene            2425..3702
                     /locus_tag="TVB59_001623"
     CDS             2425..3702
                     /locus_tag="TVB59_001623"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEL1010494.1"
                     /translation="MRAVDLIQKKRDGKELSTEEIQWLINGYANGTVPDYQMSAFAMA
                     IYFKGMSTRETRDLTMSMVETGEQIDLSAIAGIKTDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTLDKLESIKGFQIGRTQEEFIKQVQEIGLSVIGQSDKLVKA
                     DKLLYALRDVTATVDIVPLIASSVMSKKIAAGADSILLDVTVGDGAFMKTIEDAEKLS
                     RLMVDLGKEVGRQTVAVITDMSQPLGRAIGNRLEVLEAIDIMKGKGRKDITHFICELA
                     QIMLELAGAQHSLEDIHHHLVGGAALKKLEEMVVYQGGDLEDLYRPSQAAVQTEVFAS
                     EDGYITALPALEFGLFAMRLGAGRAVKTDSLDYETGIVFDKKVGDAVAKGERIAVVFS
                     QEALDEKMLTEFEKNVKIGAEHLEANEIIKIIS"
     gene            3716..4378
                     /gene="deoC"
                     /locus_tag="TVB59_001624"
     CDS             3716..4378
                     /gene="deoC"
                     /locus_tag="TVB59_001624"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEL1010495.1"
                     /translation="MNINKYIDHTLLKADSVQSQLDQLIEEAKAYDFASVCVNPCWVA
                     YAAKALKGTDVKVCTVVGFPLGATTSATKAFETKDAIENGADEIDMVINIGLLKQGDY
                     QAVEDDMRAVVEASGDKLVKVIIEACLLTDDEKVKACQLAVNAGVDFVKTSTGFSTGG
                     ATVSDVKLMRQTVGPDIGVKAAGGARSLEDALAFVEAGATRIGTSAGVTIMKGEVANG
                     GY"
     gene            4365..4754
                     /locus_tag="TVB59_001625"
     CDS             4365..4754
                     /locus_tag="TVB59_001625"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEL1010496.1"
                     /translation="MEATDLVSLAIEASKRAYVPYSHFPIGAALKTKDGTIYTGNNIE
                     NASFGLTNCGERTAIFKAVSEGHQQLLEIAIYGETDEPISPCGACRQVMAEFFEATAP
                     VTLIAKDGRTMRTTVGELLPYSFTDLS"
     gene            4845..5897
                     /locus_tag="TVB59_001626"
     CDS             4845..5897
                     /locus_tag="TVB59_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEL1010497.1"
                     /translation="MNKKFIGVGLASVALLGLVGCGNRNASKGSGDAKTDLKVAVVTD
                     TGGVDDKSFNQSAWEGLQAWGKDNGLTKGSGFDYFQSTNESEYATNIDTAVSSGYEVV
                     YGIGFALKDAISKAADDNNKVQFVIIDDVIEGKDNVASVTFADNEAAYLAGIAAAMTT
                     KTKTVGFVGGMEGTVVTRFEKGFEAGVKSVDDSIKIKVDYAGSFGDAAKGKTIAAAQY
                     AAGADVIYQVAGGTGAGVFNEARTINEKRDEADKVWVIGVDRDQNEEGKYTSKDGKSS
                     NFVLASTIKGVGKAVQLINKQAADKKFPAGKTTVYGLKDGGVEIATTNLSKDVIKAIE
                     EAKEKIKSGDVKVPEK"
     gene            6024..7556
                     /locus_tag="TVB59_001627"
     CDS             6024..7556
                     /locus_tag="TVB59_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1010498.1"
                     /translation="MAQHVIEMKEITKKFGDFVANDHINLNVRKGEIHALLGENGAGK
                     STLMNMLAGLLEPTSGNIVINGQPVVIDSPSKSARLGIGMVHQHFMLVEAFTVAENII
                     LGNEVVKNGCLDLKKASKDIKELSEKYGLAVDPTAKIADISVGAQQRVEILKTLYRGA
                     DILIFDEPTAVLTPAEIQELMEIMRNLVKEGKSIILITHKLDEIRAVADRVTVIRRGK
                     SIQTVDVAGATSQDLAEMMVGRSVSFTTAKKAAEPKGVVLSIKNLEVDENRGIPAVKG
                     LSLDVRAGEIVGIAGIDGNGQSGLIQAITGLRKTRSGSITIKGQEVVHLSSRKITELS
                     VGHVPEDRHRDGLVLDLSLAENTALQTYYKEPLSKNGILNYNTINDYARRLMKEFDVR
                     GANELVPARGFSGGNQQKAIIAREVDRNPDLLIVSQPTRGLDVGAIEYIHKRLIEERD
                     KGKAILVVSFELDEILNLSDRIAVIHDGKIQGIVLPQDTNKQELGILMAGGSIDKEES
                     HV"
     gene            7549..8613
                     /locus_tag="TVB59_001628"
     CDS             7549..8613
                     /locus_tag="TVB59_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1010499.1"
                     /translation="MSKNAQKIAVPMISILLGFLLGAIVMFIFGYDPIWGYEGLFQVA
                     FGSIKNIGEIFRAMGPLILIALGFTVASRAGFFNVGLSGQALAGWIAAGWFALVNPNM
                     PRPLLILMTVLIGMVAGGIAGAIPGILRAYLGTSEVIVTIMMNYIILYVGNAIIQRGY
                     PESVKQSIDSTIQVSDNASYQSQWLSDLTNNSRINIGIFFALIAIAVIWFLLNKTTLG
                     FEIRSVGLNPHASEYAGMSLKRTIILSMIISGALAGLGGVVEGLGTFENVFVQGSSLA
                     IGFDGMAVSLLAANSPIGIFFSSFLFGVLSIGAPGMNIAGIPPELVKVVTASIIFFVG
                     AHYLIERYIIRPKKLVKGGK"
     gene            8615..9571
                     /locus_tag="TVB59_001629"
     CDS             8615..9571
                     /locus_tag="TVB59_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002268043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1010500.1"
                     /translation="MSLVTIFALLVSSMLIYATPLIFTSIGGTFSERAGVVNVGLEGI
                     MVMGGGSGIVFNLEFAHIFGKATPWLAVLVGGVVGLIFSLIHALATINFRADHIVSGT
                     VLNLLAPSLAIFLVKVMYGKGQTDNIQQSFGKFDFPILSKIPVLGDIFFRNTSLVGYL
                     AVAFSFLAWFVLYKTRFGLRLRSVGEHPQAADTLGINVYLMKYYGVMISGFLGGIGGA
                     VYAQSISVNFAVTTILGPGFIALAAMIFGKWNPVGAMLSSLFFGLSQSLAVIGAQLPV
                     LEKIPTVYLQIAPYLLTIIILAAFFGQAVAPKADGVNYIKSK"
     gene            complement(9609..10865)
                     /locus_tag="TVB59_001630"
     CDS             complement(9609..10865)
                     /locus_tag="TVB59_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEL1010501.1"
                     /translation="MEHLNNTTQLIGIKDKHITLTKAIQHDTHIEVIATLDYNPPKCK
                     LCAGKQIKYDFQKPSKIPFIEIGGFPSLIRLKKRRFQCKSCRKVTVSETTLVKKNCQI
                     SEIVRQKIAQLLLNRKALTHIASKLAISTSTVYRKLKQYHFREDYANLPEVLSWDEFS
                     YQKGKLAFIAQDFNTKKIITILDNRRQTTIRNHFFKYSKEARNKVKVVTVDMSGSYIP
                     LIKILFPKAKIVLDRFHIVQHINRALKQIRSDIMKPFDKKSLKYRALKYYWKLIQKDS
                     RKRSLKPFYSRTFRQTLTPRECLNKIFSLVPELNSYYDLYQLLLFHLQEKNAKHFFGL
                     IHDTLPHLNQTFKTALNTFSRYQDYITNAIQLPYSNAKLEATNKLIKDIKRNAFGFRN
                     FDNFKKRIYLALNITKEKTTFVFSRA"
     gene            complement(11385..13100)
                     /locus_tag="TVB59_001631"
     CDS             complement(11385..13100)
                     /locus_tag="TVB59_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEL1010502.1"
                     /translation="MTYTENYQKWLDIPDLPAYLRDELLSMDEKTKEDAFYTNLEFGT
                     AGMRGYIGAGTNRINIFVVRQATEGLAALVESKGEAAKKAGVAIAYDSRHFSPEFAFE
                     SAQVLAAHGIKSYVFESLRPTPELSFAVRHLGAFAGIMVTASHNPAPFNGYKVYGSDG
                     GQMPPADADALTDYIRAIDNPFAIRLADLEKAKANGLIEVIGEAVDLAYLEEVKKVNI
                     NQDLINDYGRDMKIVYTPLHGTGEMLARRALAQAGFKSVQVVEVQAKPDPDFSTVKSP
                     NPESQEAFTLAEELGRQVDADVLVATDPDADRLGVEIRQADGSYRNLSGNQIGALIAK
                     YILEAHQQAGTLPNNAALAKSIVSTELVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNYTYMFGFEESFGYLIKPFVRDKDAIQAVLLVAEIAAYYRSRGLTLADGIDDIYKE
                     YGYFAEKTISVTLSGVDGAAEIKQIMDKFRKHAPAQFNHTDIVLTEDFLSQTATHKAG
                     QTQLTTPPSNVLKYTLADDSWFAVRPSGTEPKIKFYIATVGDTLALAEEKIANIESEI
                     NAFVS"
BASE COUNT         3781 a         2330 c         3061 g         4041 t
ORIGIN      
        1 gcgatcaaga cgcagaacag gggctatagc agcctgatgt gagacaggaa ggacttactg
       61 tcctaccagc tacagtcact acactgctag agcttgcggt gtgagcagca gtaagaggca
      121 aaggcgttac cccagaggga ttgatggatc accatcacta gtttggagcc attagctgtg
      181 ccaaaggttt tctaaagcca aaaagaaaaa actccgattg gagttttcat tggttatgta
      241 ttagctaagc tttgcagcaa gacgtgcttt atcgcggctt gctttatttt tatgaatcaa
      301 accttttgat tgggctttat caatgcttga agaagcagcg cggaaaagct cttcagatgg
      361 gttagcttca aatgccttga tagcagtacg catagctgat ttttgtgctg aatttttttc
      421 gtttgcttta acgttaagct cagcgcgttt aatagctgat ttaatatttg ccaatgtttt
      481 cacctccaaa ttaatctaac tacaccatta tatagaaaat ataggtgttt ggcaagcact
      541 tatcactttt tgagataaat ttcatcaatt ttatggtctg cagctttatg aagaatgagc
      601 tcagctcgat tgcgtgtagg ctcaataaac ttttccagat tttctaggtt aattgttttc
      661 cagacttttt ttgcaaaggc aatggcttca ttttgtggca atgaggtata tctagtgtaa
      721 tagttagccg gatcatgctt agccagctct aaaaggctta agaaccgttc caaataccat
      781 tgctcaatat gatggctatc tgcgtcaata taaattgaaa aatcaaaata atcactcata
      841 tacaatcgat tattctgttg attttgaaaa acattaatcc cttcgatgat gaggaagtca
      901 ggattggtaa aggtttgctg ctgatcagga acgatatcat aaatctcatg cgagtaaaca
      961 ggggctgatg cggtttgtcc tcccttgaca gtatccagaa agtttaacaa tagctccata
     1021 ttataggatt ctgggaagcc ctttcgattc agcatattgt ttttgatcag tgtgctatta
     1081 gggtacaaaa aaccatctgt tgtgaccaac tcaacagtgc tggtcttgtg tgtgcgcgcc
     1141 aaaagaagct gcaataacct gctagttgtg gacttaccga cggcaactga gccagaaatc
     1201 ccaataataa agggtctttg ctgaatatct ttttttagaa agaggctttt agaaaaagac
     1261 aggttttctt gagcgatttt atagacttga atgagatgaa tcaagggaag gtaaacctca
     1321 acaacgtcgt tgatatcaat attatcattc aaactggtga tgctagtaag ctcctcttga
     1381 gtcaataagg gcttgctttt ttgatgtaat tgcttccagg attttctgga aattttttca
     1441 aaagtaataa attcgtttga catagttact cctactaatt ggcagtgctt acattataac
     1501 atgtcaataa aaaaattgaa aaatgtttcg tctgaaattc ttaaaaaaac actgaaaaac
     1561 cctataaaaa tcgaacaatt ttagcctaac aattggctaa tataaagtta atcggtcaat
     1621 gttcggaata tatggttcga taaacgaaaa accaagaaaa acaaacgtct tgtaaaccat
     1681 ttcaaagtgt gatagaatga aaaagcatcg aaaaaagata ggaaaacaca tgacaaaaat
     1741 gtattatgat gaaaatccag atagtgctca tgatatccat caattgacgg tcaatttgtt
     1801 aggacagtcc tttacttttt tgacagattc tggtgttttc tcaaaaagaa tggttgattt
     1861 tggaagtcag gtcctgctca acacattaga ttttcaagaa ggtgatcgtc tgcttgactt
     1921 gggctgcggc tatgggccgc taggacttag cttggcaaag gctcaaggtg ttgaggcgac
     1981 tctagtagat attaatcatc gcgctgttgg cttagctaag cagaatgctg agagtaatca
     2041 ggttgaggcg accatttttc aatcaaacct ctatgacggt gtgacaggga catttgagca
     2101 catcattagt aacccaccta ttagggcagg gaaaaaagtg gttcatgaga ttattgaaaa
     2161 gagtattgat tttttaacta aaggcggtga tttgacagtc gttatccaaa agaagcaggg
     2221 agcaccaagt gctaaagaca aaatggaggc cgtttttggg aatgtgacta ttctcaaaag
     2281 agaaaagggt tactacattt taagaagtat taaggaaagg aattgagctc aagtgtaaaa
     2341 agtggtatta aaaagcatag cggtatttta gtaagagttg ccttctaata tcactatttt
     2401 ctcagagctt ttggtatctt gttgatgaga gcagttgatt taatccaaaa aaagcgtgat
     2461 ggtaaagagc tatctaccga agagatccag tggctgatta atggttatgc caatggtact
     2521 gtgccagatt atcaaatgtc ggcttttgca atggcgatct atttcaaggg aatgtctaca
     2581 cgagaaactc gcgatttgac catgagtatg gttgagacag gtgagcagat tgatttgtca
     2641 gctatagctg gtatcaagac ggacaagcac tcaacaggtg gtgttggtga taaggtgaca
     2701 ctcatcttag ctcctctagt tgctagcttt ggcgttcctg tagcgaaaat gagtggacgc
     2761 ggcttaggcc acaccggtgg aacgcttgat aagctagaat ctatcaaggg ctttcagatt
     2821 ggtcggaccc aagaggaatt tatcaagcag gtacaagaga tcggactttc agttattgga
     2881 caatcagata agcttgtgaa ggcagataag ctgctttatg ctcttcgtga tgtgacggca
     2941 accgttgata ttgttccttt gattgcaagc tctgttatga gtaagaaaat tgctgctggc
     3001 gctgatagta ttttgctaga tgttaccgtt ggtgacggtg cctttatgaa gactattgaa
     3061 gatgctgaga agctgtctag actgatggtt gaccttggta aggaggttgg gcgtcagaca
     3121 gtggctgtca ttacagatat gagtcagcct cttggtcgtg ctatcggtaa tcgcttagag
     3181 gtgctagagg caattgatat catgaaaggc aagggacgca aggatattac tcactttatt
     3241 tgtgagctag ctcagattat gctggagctt gctggtgctc aacactctct tgaggatatt
     3301 caccatcatt tggttggcgg agcagcctta aaaaaattag aagagatggt tgtttatcaa
     3361 ggaggtgatc ttgaggacct ttatcgtcca tcacaggcgg ctgttcaaac agaggttttt
     3421 gcgtcagaag atggttacat cacagcattg cctgctcttg agtttggatt gtttgcaatg
     3481 aggctgggtg ctggtagagc agtcaaaaca gatagtctgg attatgaaac agggattgtc
     3541 tttgacaaga aggttggtga cgctgtcgct aagggagagc gcattgcagt tgtcttttca
     3601 caggaagccc tagacgaaaa aatgcttaca gaatttgaaa aaaatgttaa aataggggcg
     3661 gaacacctag aggctaacga aattatcaaa atcatttcct aaggaggagt ataacatgaa
     3721 tattaacaag tatattgacc acacactact aaaagctgac agcgttcaat cgcagcttga
     3781 ccaattaatt gaggaggcta aagcctatga ctttgctagc gtttgcgtca acccttgctg
     3841 ggtagcctat gctgcaaagg ctttaaaggg aacagatgtt aaggtttgta cagttgttgg
     3901 ttttccttta ggtgcaacta cctcagcaac aaaggccttt gaaacaaagg acgctattga
     3961 aaatggtgct gatgagattg atatggttat caatattggt ctgttaaagc agggtgacta
     4021 ccaagctgtt gaagatgata tgcgtgcagt ggtagaggct agcggagaca aattagtcaa
     4081 ggtgattatc gaggcttgcc tcttgactga tgatgaaaag gttaaggctt gtcagttggc
     4141 ggtaaatgca ggtgttgact ttgtgaagac ctctactggt ttttcaactg gcggtgcaac
     4201 cgtttctgat gtcaagctaa tgcgtcaaac agttggtcca gacattggcg taaaggcagc
     4261 tggtggtgct cgttctctag aggacgcttt agcttttgtc gaagcaggag ctacacgtat
     4321 tggaacttct gcaggggtaa ctattatgaa aggtgaagtt gccaatggag gctactgatt
     4381 tagtttcgtt agccattgaa gctagtaaaa gggcttatgt gccttactca catttcccga
     4441 tcggagctgc tttaaagaca aaggacggaa caatctatac tggcaataat atcgagaatg
     4501 ccagctttgg cttgaccaat tgtggggagc gaacagctat ttttaaggct gtttctgagg
     4561 gacatcagca gcttttagaa attgccattt atggagagac tgatgagcca atctctcctt
     4621 gtggagcctg tcgtcaggtc atggcagaat tttttgaagc cactgctcca gtaacgctaa
     4681 ttgctaagga cggtcgtacc atgcgcacaa ctgttggcga gttacttcct tattcgttta
     4741 cagatttatc gtaatctggc ttaattttgt tatctagcca ttaggcttta tatttacttt
     4801 cggcaattgg tttgctagaa atatttttag gagggttcat attcatgaac aagaaattta
     4861 ttggtgttgg tttagcttct gtagctttat taggtttagt tggttgtggt aatcgtaacg
     4921 cttcaaaggg atctggtgat gctaaaacag atttgaaggt agcagtggtt actgacactg
     4981 gtggtgttga tgataagtca tttaaccaat cagcttggga aggcttgcag gcttggggta
     5041 aggacaatgg actaacaaag ggttcaggct ttgattactt ccaatctaca aacgagtctg
     5101 aatatgcaac taacattgat acagcagttt ctagtggtta tgaggttgtt tatggtatcg
     5161 gatttgcctt gaaggatgca atcagtaagg ctgctgatga caacaacaaa gtacaatttg
     5221 ttatcattga tgatgttatc gaaggcaaag acaatgttgc tagcgtaaca tttgctgata
     5281 acgaagctgc ttaccttgca ggtattgcgg cagctatgac tacaaaaaca aaaacagttg
     5341 gttttgtagg tggtatggaa ggaacagttg ttacacgctt tgaaaaaggc tttgaggcag
     5401 gcgttaagtc tgttgatgac tcaatcaaga tcaaggtgga ctacgctgga tcatttggag
     5461 atgccgctaa gggtaagaca attgcagcag cgcaatacgc agcaggtgct gatgttatct
     5521 atcaggtagc tggtggaaca ggtgcgggtg tcttcaacga agcaagaaca attaacgaaa
     5581 aacgtgacga agctgataag gtttgggtaa ttggtgttga ccgcgaccaa aacgaagaag
     5641 gtaaatatac atctaaggat ggcaaatcat ctaactttgt acttgcatct actataaaag
     5701 gtgttggtaa ggctgttcaa ttgatcaata agcaggcagc agataagaaa ttccctgcag
     5761 gtaaaacaac tgtttatggt ctgaaggacg gtggtgttga gattgccaca acaaatcttt
     5821 ctaaagacgt tatcaaagcc atcgaagaag cgaaagaaaa aattaaatct ggtgacgtaa
     5881 aagttcctga aaagtagtta ctggaaaaga gcgaccttcg tcggtcgccc tttttagagt
     5941 ggaacacctt ttgcttcagt aaaggttgtg acaaatggct ggctttactg aaacaaaaga
     6001 ttaaattgaa aggaaataat cctatggcac agcatgtcat tgaaatgaaa gagattacaa
     6061 aaaaatttgg tgattttgtt gcgaatgacc atattaattt gaatgtcaga aaaggcgaaa
     6121 ttcatgcatt gttaggagag aatggtgcag gtaaatcaac gttaatgaat atgttagctg
     6181 ggcttttaga gccaactagt ggaaacattg tcattaacgg tcagcctgtt gttattgact
     6241 ctccttccaa atctgctaga ttgggtattg gaatggtaca ccagcacttt atgctagtag
     6301 aagcttttac agttgctgag aatatcattt taggaaatga agttgtcaaa aacggttgtc
     6361 ttgatttaaa aaaggccagc aaggacatta aagagctttc tgagaaatat ggtttagctg
     6421 ttgatcctac tgccaagatt gctgatattt ctgtaggggc acagcagcgt gttgaaatct
     6481 taaagacctt atatcgtggt gcagatattc ttatttttga tgagccaaca gctgttttaa
     6541 cgcctgctga aatacaagag ctcatggaaa tcatgcgtaa ccttgttaag gaaggcaaat
     6601 ccattatttt gattactcat aagctggacg aaattagagc agttgctgat agagtcactg
     6661 ttattcgacg tgggaaaagt attcaaacag tagatgtagc aggtgcaacc tctcaggact
     6721 tggctgaaat gatggttggg cgttcagttt cctttacaac agctaaaaag gcagcagagc
     6781 caaaaggggt ggtgctgtcg atcaagaatt tagaggtcga tgaaaatcgt ggaatcccag
     6841 cagtaaaggg gctttctctt gacgttagag ctggtgaaat tgtggggatt gcagggattg
     6901 atggtaatgg tcagtcaggg ctgattcagg ccattacagg cttgagaaag actagatctg
     6961 gtagcattac aatcaaaggt caggaggttg ttcatttaag ctcccgtaaa atcacagagc
     7021 tatcagtggg gcatgtgcct gaggaccgtc atagagatgg cttagtgctg gacctttcct
     7081 tggctgaaaa tactgccctt cagacctatt ataaagagcc actaagtaag aacggtattt
     7141 taaattacaa tacaatcaat gattatgctc gtagactgat gaaggaattt gacgttcgtg
     7201 gtgccaatga attggttcca gctcgtggat tttctggcgg taaccaacaa aaggctatca
     7261 ttgcacgtga ggttgaccgt aaccctgatt tattgattgt cagtcagcca actcgcggct
     7321 tggacgttgg tgctattgag tacattcata agcgtttgat tgaagagcgt gacaaaggca
     7381 aggccatcct cgttgttagc tttgagcttg acgaaatctt gaatttatct gaccgtattg
     7441 cagttattca tgacggtaaa attcaaggca ttgtgttgcc tcaagatacc aataagcaag
     7501 aattgggaat tttgatggct ggtggttcca ttgataagga ggagagtcat gtctaaaaat
     7561 gcacaaaaga ttgctgtgcc aatgatttct atcttgttag gattcttact tggcgctatt
     7621 gtcatgttta tctttggcta tgatccaatt tggggctatg agggcctatt tcaggtagcc
     7681 tttggtagta tcaaaaatat tggtgaaatc ttcagagcga tgggaccact aatcctgatt
     7741 gcacttggtt ttaccgttgc tagccgtgcc ggcttcttta atgtcgggct gtcaggtcaa
     7801 gctttggctg gttggattgc tgcgggctgg tttgctcttg tcaatcctaa tatgcctcgt
     7861 ccgcttttaa ttctgatgac tgtcttgatt ggtatggttg ccggcggaat tgctggcgct
     7921 attccaggta ttttgcgagc ttatcttggt acgagtgaag ttattgttac cattatgatg
     7981 aattatatta ttctgtatgt cggtaacgct atcattcaaa gaggctaccc tgaaagtgtt
     8041 aagcaaagta ttgattcaac catacaggtc agtgataatg ccagctatca aagtcaatgg
     8101 ctgtcagatt taaccaataa ttctcgtatt aatatcggta tcttttttgc gcttattgca
     8161 attgcagtta tttggttctt actaaacaaa acaaccctcg gatttgaaat tcgttcagta
     8221 ggtcttaatc cacatgcttc agaatatgca ggtatgtcct taaagcgtac gattatccta
     8281 tcaatgatca tttcaggtgc tttagcaggc ttgggaggag ttgttgaagg cttgggaacc
     8341 tttgagaatg tttttgtaca gggaagctct ctagcaattg gttttgacgg tatggctgtt
     8401 agcttgcttg ctgccaattc accgattggt atcttcttct catcattcct atttggggtg
     8461 ttgagcatag gtgctcctgg tatgaatatc gcaggaattc caccagaatt ggtaaaagta
     8521 gtgactgcct caattatctt ctttgtaggt gctcactacc ttatcgaacg ctatattatc
     8581 aggcctaaaa aactagtaaa gggaggtaaa taagatgagt ttagttacta tttttgcttt
     8641 attggtttca tcaatgctta tctatgctac acctcttatt tttacaagta ttggtggtac
     8701 cttctcagaa cgagctggtg ttgtcaatgt cggccttgaa ggcattatgg tcatgggggg
     8761 gggttcaggc attgtcttta atcttgaatt tgctcatatc tttggtaaag ctactccctg
     8821 gcttgcagtt ttggtgggag gagttgttgg attgatcttt tcattgatcc atgcgcttgc
     8881 aacgattaac tttagggcag atcacattgt cagtggtaca gtgctaaatc tgctggcacc
     8941 atcgcttgcc attttcttag ttaaggtgat gtacggtaag gggcaaactg ataatatcca
     9001 gcaatcattc ggtaagtttg attttccgat tctctcaaaa attccagttc ttggagatat
     9061 attctttaga aatactagct tagttgggta tttagctgtt gccttttctt tcctagcttg
     9121 gtttgtgctt tacaaaacaa gatttgggtt gcgtttgcgc tctgtaggtg aacaccctca
     9181 agcagctgat acacttggta ttaacgttta cctcatgaaa tattatgggg ttatgatctc
     9241 tggttttctt gggggtattg gtggagctgt ctatgcacaa tccatctctg ttaacttcgc
     9301 agtgacaacc attttaggac ctggatttat tgcccttgcc gctatgattt ttggtaagtg
     9361 gaatccggta ggtgctatgc tatctagctt gttctttgga ttatcacaaa gcttagcagt
     9421 tattggggca caattaccag tattggaaaa aatcccaacg gtttaccttc aaattgcgcc
     9481 atacctattg accatcatca ttttggctgc tttctttgga caagcagtgg ctccaaaggc
     9541 agacggtgtt aattacatca aatcaaaata aaaaaagctc aatgtcaact gtagtgggtg
     9601 actgatagct aagcacgaga gaagacgaat gtcgtcttct cttttgtgat attcaaagcg
     9661 aggtagatac gttttttaaa gttgtcaaag ttccgaaatc cgaaagcatt gcgcttgata
     9721 tctttgataa gtttgttagt ggcttctaac ttagcgttag aataaggcag ttgaatggca
     9781 ttggtgatgt aatcttggta gcgactaaag gtatttagag ctgttttaaa agtctgatta
     9841 agatgtggta gtgtgtcatg aattaaacca aagaaatgct tggcattctt ttcttgcagg
     9901 tgaaaaagga gcagctggta caggtcataa taagagttta actcaggcac tagtgagaag
     9961 atcttattga gacattctct aggagttaag gtttgtctga aggtgcggga atagaaaggc
    10021 ttaagagacc gttttctgct atccttttga ataagcttcc agtagtactt aagagctcta
    10081 tatttaagag acttcttgtc aaatggtttc atgatgtcac tacgtatttg cttgagagct
    10141 ctattgatgt gctggacaat gtgaaaacga tcgagaacga ttttagcctt aggaaataga
    10201 attttaatga gaggaatata acttccagac atatcgacag tgacgacttt caccttgttt
    10261 ctagcctctt tagagtactt aaagaaatga tttcggatgg ttgtttgacg tctattatca
    10321 agaatggtaa tgattttctt agtgttaaaa tcctgagcaa tgaaggctaa tttacctttc
    10381 tgataagaga actcatccca agagagaact tctggcaaat tggcgtaatc ctctcggaaa
    10441 tgatactgct taagcttgcg atagacggta gaagtggaga tagcgagctt agaagcgata
    10501 tgggtgagag cctttctgtt gagtaaaagc tgagcgattt tctgtctcac tatctcagaa
    10561 atttggcaat ttttcttaac cagggtagtt tcagatacag tgacttttcg acaggatttg
    10621 cattgaaacc ttcttttttt caaacgaatg agactaggaa agcctccaat ttcgataaag
    10681 ggaattttag agggcttctg gaagtcgtat ttgatttgtt ttcccgcaca cagtttacat
    10741 ttaggagggt tatagtctag tgtagcgatg acttcaatat gagtatcatg ctggatagct
    10801 ttagtcaagg tgatatgttt gtctttgatt ccaatgagtt gtgtggtatt attgaggtgt
    10861 tccataagat accttctaaa tgatagttta gtcgcttttc atgataagtc ttatgggact
    10921 tttttgatac tcaaaaagcc ctataatctc cacagtagcc ttacccacta cagaaattat
    10981 agagccatct tagaacactg gacttgttcg ctttttaatg aattaaattt agtagatcct
    11041 ttaaaggcat gctatcaagc tttttatcct tgacttttgt ttagcaagtg aagtgttcac
    11101 aaaagctagc taaaacactg agctgacaat gtagagaatg gctcgttttg acaaggttag
    11161 agtgcttttt gctgtatggt ttttaatcca cgcacctgaa aaagaaagga caggacctgt
    11221 gcgagcttac ttgtggttag taggtttcaa ttcatgctcc caaaaaggaa gcaacgcaac
    11281 tctgagaaag gtcttagacc actttcccag tttgcctcac agctaatggt gtaaaacaaa
    11341 tagaccaccc tgtaacaggt ggtcatggtt agatatcagc tcatttaaga gacaaaggcg
    11401 ttgatttcag attcaatatt ggcaattttt tcttcggcaa gcgcaagggt gtcaccaaca
    11461 gttgcgatat aaaatttaat ttttggctct gttcctgatg gtcttacagc aaaccatgaa
    11521 tcatcagcta gggtatattt taagacattg cttggaggag tggttagctg ggtttgacca
    11581 gctttatgag ttgccgtctg actgaggaaa tcctctgtta acacaatatc agtgtgatta
    11641 aactgcgcag gggcatgctt gcggaattta tccataatct gtttgatttc agctgcgcca
    11701 tcaacaccag acagtgtaac agaaatggtt ttttctgcaa agtagccgta ttctttgtaa
    11761 atgtcatcaa taccatcagc aagggttagt ccacgagagc ggtagtaggc agcaatctca
    11821 gccaccaata gcaccgcttg aatagcgtcc ttatcacgta caaatggttt aatgagataa
    11881 ccaaagctct cctcaaagcc aaacatatag gtgtaattgt gcttttcttc aaattcttga
    11941 attttttcag caatgaactt gaagcctgtt aagacattaa acatggttgc cccgtagctc
    12001 tctgcaattt tagtcactaa ttcagtagag acaatggatt tggcaagagc ggcattgtta
    12061 ggtagggttc cagcctgctg atgtgcttct aaaatatact tagcaattaa agcaccaatt
    12121 tggttgcctg ataggttgcg atagctgcca tctgcctgcc gaatttcaac cccaagacgg
    12181 tcagcatctg gatcagtagc aacaagaaca tcagcatcaa cctgacgtcc aagctcctca
    12241 gcaagagtaa atgcctcttg actttcagga ttaggagatt tgacggtaga aaaatctgga
    12301 tctggcttag cctgcacctc aaccacctga acggacttaa agcctgcttg tgccaaggca
    12361 cgacgtgcta gcatttcacc tgttccatga agaggtgtat agacaatttt catgtcacga
    12421 ccatagtcat tgatgaggtc ttggttgata ttgacctttt tgacctcttc taaataagca
    12481 aggtcaacag cttcaccaat aacctcgatg agcccattag ctttggcttt ctctaaatca
    12541 gcaagcctaa tggcaaaggg gttatcaatc gcacgaatgt aatctgttag agcgtcggcg
    12601 tcagctggag gcatttgacc gccgtcagac ccataaacct tatagccgtt gaatggtgca
    12661 gggttgtgac tggcagtaac catgataccg gcaaaagcac ccaaatgtcg cacagcaaag
    12721 gaaagctcag gtgttggccg aaggctttca aaaacgtatg atttaatgcc atgagctgct
    12781 agtacctgtg cagattcaaa ggcaaattct ggagaaaaat gacgagaatc ataggcgata
    12841 gcgacaccgg ccttcttagc agcttctccc tttgactcaa ctaatgctgc caagccctca
    12901 gttgcttggc gaacaacaaa aatattgata cgattcgttc cagcgccaat atagccacgc
    12961 ataccagctg ttccaaattc aagattggtg tagaaggcat cttcctttgt tttttcgtcc
    13021 atgctaagta attcatctct taaataggct ggtagatctg gaatatcaag ccatttttga
    13081 tagttttctg tgtaagtcat agtattctcc tttatatttt taaccgcttt cattatatca
    13141 tgttgaaaag gaaaaatcac ttattttctg taatagcttc caatcatttt ttcacataag
    13201 gatcaatttc ctt
//
LOCUS       DARYNN010000053        12984 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.053, whole genome shotgun sequence.
ACCESSION   DARYNN010000053 DARYNN010000000
VERSION     DARYNN010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12984)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12984)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12984
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.053"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(22..1071)
                     /gene="citC"
                     /locus_tag="TVB59_001632"
     CDS             complement(22..1071)
                     /gene="citC"
                     /locus_tag="TVB59_001632"
                     /EC_number="6.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[citrate (pro-3S)-lyase] ligase"
                     /protein_id="HEL1010503.1"
                     /translation="MTQHLIQHIFPFDKQQKAKIDRLLQRQHIRRDPHLDYTCAIIDE
                     QGEPIATGSLYGNSLRCLAVDQAYQGEGLLNHIVSHLIEEAYSRGHHHLFIYTKIAAA
                     PLLLSLGFHVIAMVDDTLCFLENKKRGFEHYLSQLEKPQISPQKTAAIVLNANPFTLG
                     HLHLIEKACADNELVHLFMVSQDSSLIPYHIRKELIIKGTAHLANIIYHDSGPYMISQ
                     ATFPAYFQKDELAVIDSQAKLDIVIFRHIAEKLQIKSRYVGEEPTSMVTQHYNTVMLK
                     QLPCYSIDVQVIPRKTFAEGKIISASLARQAIKDDDYALLELLLPKTSLDFFRSEAAQ
                     PTITKIKAATDLKHY"
     gene            1338..2401
                     /locus_tag="TVB59_001633"
                     /pseudo
     CDS             1338..2401
                     /locus_tag="TVB59_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004347311.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
     gene            complement(2487..3371)
                     /gene="citG"
                     /locus_tag="TVB59_001634"
     CDS             complement(2487..3371)
                     /gene="citG"
                     /locus_tag="TVB59_001634"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase CitG"
                     /protein_id="HEL1010504.1"
                     /translation="MTKKVFDDISRLALKALLYEVSLSPKPGLVDQLDNGAHDDMSFL
                     TFVDSALALAPFFKIYLDIGFYHAKEDPGLIFERLRASGIEAEQAMFSATKGVNTHKG
                     VNFSLALLLGATGMYLADQPQLLDHVTAFTEEDSLAICQLVKPLTAHLLETDFGSLDL
                     KKELTYGEKLFLDYGIKGPRGEASEGYPTIAHKALPFLRKSLRSTDQETAQLQLLVYL
                     MSIVEDGNLIHRGGIKAWRQVKQDMLLLHNSSLSTADLKAALSAYNDKLIQKHLSPGG
                     TADLLVLSLYFAFLENQL"
     gene            complement(3364..4059)
                     /locus_tag="TVB59_001635"
     CDS             complement(3364..4059)
                     /locus_tag="TVB59_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1010505.1"
                     /translation="MNPIIEAVKNNLDLSRNIPLKIAFYNALKKTIILRQIPAGSRIN
                     EKEFSIALNISRTPIRYALGLLSEEHLVEHIPKKGIIVKGVSIQDACEIFEIRKALET
                     LATSTAMYLMTEEDFQVMHDLLADCETFIEDDDLNRILDNFNSFNNLIYSYSQMVRLK
                     EIVTELQTYLVYFRKISISSLERRKRALSEHWMIYRGMKNRDHEQITLITHEHLNSSL
                     EFILQEMSRRQDD"
     gene            complement(4212..5615)
                     /locus_tag="TVB59_001636"
     CDS             complement(4212..5615)
                     /locus_tag="TVB59_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003088270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CitMHS family transporter"
                     /protein_id="HEL1010506.1"
                     /translation="MLLTVLAYAMIIIFMYVVMKKKMTPFTALVMIPLIMTIAVILTG
                     SADFTSDAKFVAFVGEDGLAKNLTAIGPMIMYGINNTAKTGIMLLFAILFFSIMLDAG
                     LFDPITEKMIRFAKGDPMKVLMATAIVAAAVSLNGDGTTTTLICCSAFLPIYKKLNMR
                     IMNLGVLIILQNTIMNLLPWGGPTARAMSVLSVGPEILGYLAPGMVLSLLYVICWVAP
                     SMGRKERARLGVVDLTEEEMRKLTDITDPDTLSIRRPKNFAFNAILTIGLITWLVAGS
                     FYKAIAMAPLLLFAVGTCIALIVNYPVLKDQTKRIGDNAGDAVQVVILVFAAGIFMGL
                     FQGSGMASALAQSFATIIPKQLAGFWGLVIALISAPGTFFISNDGFYYGILPVLAEAG
                     AEYGFSNMAMALASLMGQAFHLLSPLVAFIYLLLRLTGLDMGEWQKEAAKYAIIIFII
                     FVVTIIAMGQMPLYIPQ"
     gene            5997..6341
                     /locus_tag="TVB59_001637"
     CDS             5997..6341
                     /locus_tag="TVB59_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010507.1"
                     /translation="MQFFQNMFRRSKKEAATSHQDRENKPEFPLDDWEPVPSYIAADK
                     KDYQTVSLIASAIAAGEQASSQFKVKRILQRNPEALTVSLIASSIAAGVYPESQFLVR
                     SIYSKKVNVSHK"
     gene            6359..6754
                     /locus_tag="TVB59_001638"
     CDS             6359..6754
                     /locus_tag="TVB59_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010777321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein subunit"
                     /protein_id="HEL1010508.1"
                     /translation="MLRKFKITIDGKEYLVEMEEIGAPSQAPVVPPVQPAVAPAPVAE
                     KKAAEAPQAPAAPVSAGADAMPSPMPGIILKVLVNVGDVVHENQPLLILEAMKMENEI
                     VASTAGTVTGIHVTAGQVVNPGEGLITIS"
     gene            6804..7925
                     /locus_tag="TVB59_001639"
     CDS             6804..7925
                     /locus_tag="TVB59_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium ion-translocating decarboxylase subunit
                     beta"
                     /protein_id="HEL1010509.1"
                     /translation="METLIAGVTSITIPQIIMMLIGAVLMYLGIKKEYEPTLLVPMGL
                     GTILVNFPGTGVLTQVVNGVEQEGVFDALFNFGIGTELFPLLIFIGIGAMIDFGPLLQ
                     NPFMLLFGAAAQFGIFFVVVVAVLAGFDIKEAASIGIIGAADGPTSIFVANQLAKDLL
                     GPITVAAYSYMALVPIIQPFAIKLVTTKKERRIRMTYKAENVSQLTKILFPIVITLVA
                     GFIAPISLPLVGFLMFGNLLRECGVLDRLSQTAQNELVNIISILLGLTISIKMQAELF
                     LNVQTLLIIIFGLLAFIMDSIGGVMFAKFLNLFRKEKINPMIGAAGISAFPMSSRVIQ
                     KMATDEDPQNFILMYAVGANVSGQIASVIAGGLLLAYFS"
     gene            8107..8415
                     /gene="citD"
                     /locus_tag="TVB59_001640"
     CDS             8107..8415
                     /gene="citD"
                     /locus_tag="TVB59_001640"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase acyl carrier protein"
                     /protein_id="HEL1010510.1"
                     /translation="MEIKQIAVAGSLESSDMMITISPNDGQGIVLELDSSVEKQFGNH
                     IRALIKTTLARLGVESATIEAVDKGALDCTIQARTIAAVHRAAGVEHYNWKEIDSWNA
                     "
     gene            8403..9290
                     /gene="citE"
                     /locus_tag="TVB59_001641"
     CDS             8403..9290
                     /gene="citE"
                     /locus_tag="TVB59_001641"
                     /EC_number="4.1.3.34"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate (pro-3S)-lyase subunit beta"
                     /protein_id="HEL1010511.1"
                     /translation="MERLRRTMMFVPGANAAMLRDAPLFGADSIMFDLEDSVSLKEKD
                     TSRALVHFALKTFDYSNVETVVRVNSLDSCGALDIEAVVLAGVDVIRLPKTETAQDII
                     DVEAVIERVERDNGIAVGRTRMMAAIESAEGVLKAREIAKASNRLIGIALGAEDYVTN
                     MKTRRYPDGQELFFARSMILHAARAAGIAAIDTVYSDVNNTEGFQAEVRHIKQLGFDG
                     KSVINPRQIPLVNEIYTPTEKEISHAKQVIWAIREAESKGSGVISLNGKMVDKPIVER
                     AQRVIALATAAGVLTEEDI"
     gene            9292..10824
                     /gene="citF"
                     /locus_tag="TVB59_001642"
     CDS             9292..10824
                     /gene="citF"
                     /locus_tag="TVB59_001642"
                     /EC_number="2.8.3.10"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase subunit alpha"
                     /protein_id="HEL1010512.1"
                     /translation="MVKNKLGRDIPQEYADHYGVFEGELARITSYNESSRRIKPVKPG
                     DSKLLGSIREAIEKTGLKDGMTISFHHHFREGDFVMNMVLDEIASMGIKDLAIAPSSI
                     ANVHEPLIEHIKNGVVTSITSSGLRDKVGAAISSGIMEKPVVIRSHGGRARAIASGDI
                     HIDVAFLGAPSSDEYGNVNGTIGKATCGSLGYAMIDAKYADQVVVLTDHLVDYPNTPI
                     SIPQTDVDYVVTVDAIGDPQGIAKGATRFTKNPKELLIAEYAAKVITQSPYFKNGFSF
                     QTGTGGASLAVTRFMREAMLQENIKASFALGGITNAMVELLEEGLVEKILDVQDFDYP
                     SAVSLGKNAQHYEIDANMYASPLSKGSVINQLDTCILSALEVDTNFNVNVMTGSDGVI
                     RGASGGHCDTAFAAKMSLVISPLIRGRIPTFVDEVNTVITPGTSVDVVVTEIGIAINP
                     NRPDLIEHFKDLKVPQFSIEELKEKAYSIVGTPDRIQYGDKVVALIEYRDGSLIDVVY
                     NV"
     gene            10817..11377
                     /gene="citX"
                     /locus_tag="TVB59_001643"
     CDS             10817..11377
                     /gene="citX"
                     /locus_tag="TVB59_001643"
                     /EC_number="2.7.7.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase holo-[acyl-carrier protein]
                     synthase"
                     /protein_id="HEL1010513.1"
                     /translation="MSKELIFKGKAVTLADMLRAREDRSLRQGKLLTEFSNESLLSVT
                     MNIPGPIKTSPALLEVFDSVIKAILEKLSGNQISYQLRLLPKTGYEYYLVTALDSQAL
                     KLKMIELETDLPIGRLMDLDVLVLTNQLPTPISRTALGFPPRSCYLCSKEAKACSRNR
                     SHSVADMQTALVHLLQSFFDGGNQLS"
     gene            11408..12799
                     /locus_tag="TVB59_001644"
     CDS             11408..12799
                     /locus_tag="TVB59_001644"
                     /EC_number="4.1.1.112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxaloacetate decarboxylase subunit alpha"
                     /protein_id="HEL1010514.1"
                     /translation="MTKIRITETVLRDGQQSQIATRMTTKEMIPILETLDNAGYHALE
                     MWGGATFDSCLRFLNEDPWERLRTIRKVVKKTKLQMLLRGQNLLGYRNYADDVVRSFI
                     QKSIENGIDIVRIFDALNDPRNLETAVSATKEFGGHAQVAISYTTSPVHTIDYFVALA
                     KAYQAIGADSICIKDMAGVLTPETGYQLVKRIKESIALPLEVHTHATSGISEMTYLKV
                     VEAGADIIDTAISSFAGGTSQPATESMVIALEDLGIDTGVDMTRLTKIAEYFNTIRDH
                     YRAEGILNPKVKDTEPKTLLYQVPGGMLSNLLSQLKEQGLSDKYEEVLAEVPKVRADL
                     GYPPLVTPLSQMVGTQALMNVISGERYKVVPNEIKDYVRGLYGQPPAPLGEGIKEKII
                     GDEAVITCRPADLIEPQLPLLRQEIAGYACCEEDVLSYASFPQQAKDFLGRREDPFYD
                     IPVQYVTVDIAMD"
BASE COUNT         3802 a         2590 c         2874 g         3718 t
ORIGIN      
        1 tagagagggg gtagttgttg gttaataatg cttaaggtct gttgctgctt tgatcttagt
       61 tatcgtgggc tgagcagcct cgctcctaaa aaagtcaagt gaggtcttag gaaggagtag
      121 ctctaagaga gcataatcat cgtccttgat ggcctgtctg gcaagagagg cgctgatgat
      181 tttgccttct gcaaaggttt ttctagggat aacctgcaca tcaatgctat agcaaggcag
      241 ctgcttgagc atgacagtgt tgtaatgctg tgtgaccatg ctagtaggct cttcgccaac
      301 ataacgactc ttgatttgga gtttttctgc aatgtgacgg aaaatgacaa tatccaattt
      361 agcttgacta tcaataactg ctagctcatc tttttgaaaa taagcaggaa aggttgcctg
      421 actaatcatg taaggtccac tatcgtggta tatgatattt gctaggtgtg cagttccttt
      481 gatgattaat tcctttcgga tatggtaggg gatcaggcta ctgtcttgac tgaccataaa
      541 gagatgaacg agctcgttgt cagcgcaggc cttttcaatc agatgcagat gaccaagggt
      601 aaatggatta gcatttaaaa cgattgctgc ggtcttttga ggactgatct ggggcttttc
      661 tagctgtgac aggtagtgct caaagcccct ttttttattt tctaaaaaac aaagagtatc
      721 atcaaccatt gcaatgacat gaaagccaag acttagcaat agaggggcag ctgctatttt
      781 agtgtagata aacagatgat gatgcccacg tgagtaggcc tcctcaatca gatgtgagac
      841 aatgtgatta agtaagcctt ctccttggta ggcttgatca acagctaagc agcgcaggct
      901 attgccgtac aaagagccag tagcaatagg ctcgccttgc tcgtcaataa tagcacaggt
      961 ataatctaaa tgagggtctc ttctaatgtg ctgtctttgt aacaaacgat caatttttgc
     1021 tttttgctgc ttgtcaaagg gaaaaatatg ctgtatcaag tgctgcgtca tatgctcacc
     1081 tcttattacg aaattatcct cttgccttta ttatagcacg ctatagggct tattcttaag
     1141 catcttagct ggtttatgaa aagaatgcac aaaaaagaca tcaatgacct attgtctctg
     1201 atgtcattat gatatgatta ggacttttag ataaatgatt aaggtatgga ggatttaagc
     1261 ctgcaaaagg tggcaataat aattctgact tatgctataa tagagctatt gatattaagg
     1321 gggataaagg ggctggtatg ctttcgattc taatgacttt atttgttggg acgctgggag
     1381 ggcttgttgc taagcggctg agtattcctg ccccttttat gattggcagt atggtagctg
     1441 ttgccctagc ttctatcctg acaaagcagg tagaggctat taaccccatg aagatttttg
     1501 ctcagattat tagtggtgcc tatattggcc aaagcgtcag caaatctgac ctgcttaatc
     1561 tgcccaagct agccaagtct attattagtc tcatgtcctt gttcacgctg aatatgtttc
     1621 ttcttggtgg ggtatttgtt tactgctttg atcttgatcc tgtaacagcc ttgttgagct
     1681 gtttacctgg tggcattatg gacgtttctc ttatggcagt tgatatggga gcaaaggctg
     1741 atatagttgc gacattacag tcggctcgac tggtcggtat gctcttgttt cttcctgttt
     1801 gggtgacgtt ttgggtcaat cgctttgacc caaaagcaaa agctactaaa aaaaaaagat
     1861 agtcaaaagc gctagctccc aagatacaag accttctagg aaagagcagc tatggaataa
     1921 tgtccaggtt ttaagcattg ctaccattgg aggtttgatc ggtttagggc taaagatacc
     1981 tgtaggcgct ctgattgttt ctttgctttt ttcaacagca ctgaaggtgc ttcggcaaac
     2041 aagtcaaatg ccaagtacac ttcgttatat agcgcaggtt tttgctggct ctattattgg
     2101 aacaagcttt actcaggata gtttgcttca aatgggacgt ctgattgttc ctattctttt
     2161 acttttgagt agctatctga tcatcaatct cttttttggc tatatcatgt ataaaaaagg
     2221 tatcttggat ttgcaatcgg cactctttgc ctcatcgcct gctggtgcga cagacatttc
     2281 actattggct ggtgagcttg gcggagatat gcctaaaatc gctggtattc aaatcagtcg
     2341 aaccctctat actgttgtca tcatgccctt gttggttaaa tggctcatta gtatatggta
     2401 aacagaaaag cccctcagag cataaaccag agatacctag tcattaccaa ataacatatc
     2461 aaggatcttg ttcaggcttg gagctgctat aattgatttt ctaaaaaagc aaagtagagg
     2521 cttagcacta gcagatcagc agtccctcca ggactgagat gcttttggat cagcttgtcg
     2581 ttgtaggctg acaaggcagc ctttaagtca gcagtgctca aagagctgtt gtgcaatagc
     2641 agcatgtcct gtttgacttg ccgccaagct ttgatgcctc ctcggtgaat caggttgcca
     2701 tcttccacaa tagacatgag gtaaaccagc agttgcagtt gagcggtctc ctgatcagtg
     2761 ctgcgaaggc tcttgcgcaa aaaaggcagc gccttgtgag caattgtagg atagccctcg
     2821 ctggcttctc ctctagggcc ctttataccg taatctagaa agagcttctc accataggtg
     2881 agctcttttt ttaggtctaa gctaccaaaa tcagtctcaa ggagatgagc tgttagaggc
     2941 ttgacaagct gacaaatagc cagactatcc tcctcagtaa aggctgttac atggtccaag
     3001 agctgtggtt gatcggcaag atacattccc gttgccccaa gcagaagtgc taaggaaaaa
     3061 ttgactccct tatgggtatt gactccctta gttgcgctga acatggcttg ctcagcctca
     3121 atgcctgagg cacgcaagcg ctcaaagatc agaccaggat cttccttagc atggtaaaaa
     3181 ccaatgtcta aataaatctt aaaaaagggg gctaaggcca gagcgctatc aacaaaggtt
     3241 aagaagctca tgtcatcatg agccccgtta tcaagctgat ccacaagccc aggcttagga
     3301 gataaggaca cttcgtaaag taaagccttt agagcaagcc tgctaatatc atcaaatacc
     3361 ttcttagtca tcctgacgcc tgctcatttc ctgtaggata aattctagtg agctgttgag
     3421 gtgctcatgc gtaataaggg tgatttgctc gtggtcacga tttttcatgc cacgataaat
     3481 catccaatgc tcagataaag cgcgttttcg tctttctagg gaagagatcg aaatttttct
     3541 aaagtaaaca aggtaggtct gcaattcagt gacaatttct tttaatctga ccatctgact
     3601 atagctgtaa atcagattat taaagctgtt gaaattatct agaattctgt tgagatcgtc
     3661 atcttctata aaggtttcac aatcagccaa caaatcatgc atgacctgaa aatcttcctc
     3721 tgtcatcaaa tacatagcgg tgcttgttgc cagtgtttca agcgcttttc tgatttcaaa
     3781 gatttcacaa gcatcttgaa tactaacacc cttgacaata atgccttttt taggaatatg
     3841 ctctaccaaa tgctcctctg ataacaatcc tagagcgtac ctgattggtg ttctgctaat
     3901 atttagggca atggaaaatt ctttttcgtt gatacgactg ccagcaggaa tttgtcttaa
     3961 aataatagtt ttctttaggg cgttataaaa agctattttc aaagggatat tgcgggatag
     4021 gtcaagatta ttctttactg cttcgataat aggattcata taatctcctt aatgttcata
     4081 tcatgatatt attatactga aaatcattac taatgaaaat aataattagc ctcctaaaag
     4141 gcgaaagcca tgctcgtgaa agaacatggc tttcattagc ccacactaca gtcctaataa
     4201 tagctcgtga cctattgtgg aatgtaaagc ggcatttgtc ccattgcaat aatggttaca
     4261 acaaagataa taaagataat aatcgcgtat ttagcagctt ctttttgcca ttctcccata
     4321 tcaagcccag taagacgaag aagcaggtaa ataaaggcca ccaatggact gagcaaatgg
     4381 aaggcttgtc ccatcagaga agcaagagcc atcgccatgt tgctaaagcc atattcagct
     4441 ccagcctccg ctaagactgg caaaatacca tagtagaagc catcatttga gataaagaaa
     4501 gtaccaggag ctgaaatcag ggcaataaca agtccccaga agccagccaa ttgctttgga
     4561 ataatcgttg caaagctttg agcaagagca ctagccatac cagagccttg gaaaagtccc
     4621 atgaagatac cagcagcaaa aaccagaata acaacctgaa cagcatcacc ggcattatca
     4681 ccaatacgct ttgtttggtc ctttaggaca ggatagttaa caataagggc aatacaggtt
     4741 cccactgcaa ataaaagaag tggtgccata gcaatagcct tatagaaaga gccagcaacc
     4801 agccaagtga ttaagccgat ggttaagata gcattaaagg caaagttttt aggacgacgg
     4861 atagaaagcg tatctggatc tgtaatgtct gttagcttac gcatttcctc ttcggtcaaa
     4921 tcaacaacac caagtcttgc acgctccttg cgtcccatgc ttggcgcaac ccaacaaatg
     4981 acataaagaa gagacaaaac cataccaggt gcaaggtatc caaggatttc aggtcccaca
     5041 ctaagcacag acatggcacg cgcagttgga ccaccccaag gaagcaggtt catgatagtg
     5101 ttttgcagga taatcaagac accaagattc atgatgcgca tgtttaattt cttatagatt
     5161 ggtaaaaaag cagagcagca aatcaaggtt gttgttgtac catcaccatt aagtgaaaca
     5221 gctgctgcaa caattgcagt tgccatcaag accttcatcg ggtctccctt agcaaagcga
     5281 atcatttttt cagtaatcgg gtcaaacaag ccagcatcta gcataatgga aaagaacagg
     5341 atcgcaaaaa gcagcataat acctgtctta gcagtgttat taataccgta catgatcata
     5401 ggaccaatag ctgtcagatt tttagcaagc ccatcctcac caacaaaggc aacaaatttg
     5461 gcgtctgatg taaaatcagc agagcctgtt aatataacag caattgtcat tatcaacgga
     5521 atcatgacca gagctgtaaa aggggtcatt tttttcttca tgacgacata catgaagata
     5581 ataatcatag cataagctag aactgttaat aacatattgt tatctccttt ttgattttat
     5641 gacttcagta taaatgaaag cgttcgcaaa agaaatacct ccatgtacgg aaaaacacaa
     5701 aaaaaacatt ttgaaagcag atcctgaaaa aataaatggt tacattaatg tttttcaaca
     5761 gcagttagtt gctcttatct tcagtaatcg cagtgtgttt cagcattttt taaaatcagt
     5821 catatttatt ttagttaact gtttttataa aaatggttaa ctaaaataag aaaatccttg
     5881 aaaatgtgaa agcgctctta gaaagaacac aaaaaagcca ttccaaaagg atgaggtggt
     5941 atataataag catagaagct tcccatttgt gggcaaacta agaaaggagg tagcttatgc
     6001 agttttttca aaacatgttt agacgctcta aaaaagaggc agccacaagc catcaagaca
     6061 gagaaaataa gcctgaattt ccgttagatg actgggagcc agtgcctagc tacattgctg
     6121 cagataaaaa ggattatcag acagttagtc tgattgccag tgccattgca gctggcgagc
     6181 aagctagcag tcagtttaag gtaaaacgaa tcctacagcg caatcctgag gccttaaccg
     6241 tatccttaat agcatcaagc attgcagctg gtgtttatcc agagagtcaa tttctggtta
     6301 ggtccattta tagtaagaaa gtaaacgtta gccacaaata gtaaaaggag aaaagattat
     6361 gttgcgtaag tttaaaatta ccattgacgg aaaagagtac ctagttgaaa tggaagaaat
     6421 cggtgctccc tcccaagccc cagtagtacc tcctgttcaa ccagcagtag ctccagcccc
     6481 tgtagccgaa aaaaaggcag cagaagctcc gcaagctcca gcagcacctg tatcagcagg
     6541 ggcagatgca atgccctcac ctatgcctgg tattatctta aaggttttag ttaatgttgg
     6601 tgatgtcgta catgaaaatc agcctctatt gattttagag gctatgaaaa tggaaaatga
     6661 gattgtcgcc tcaacagctg gtacagtcac agggattcat gttactgcag gtcaggtggt
     6721 caaccctggt gaaggcttaa tcaccattag ctaatcctaa gtcgtgtctt gatttaaaat
     6781 gttgtagaaa aggaagtaca tttgtggaaa cattaattgc aggagtaacc tccatcacta
     6841 ttcctcaaat cattatgatg cttatcggtg ctgtcttaat gtatctagga ataaaaaaag
     6901 aatacgaacc aaccttacta gttcccatgg gactgggtac tattttagtc aactttcccg
     6961 gcacaggagt cttaacacag gttgttaatg gtgttgagca agaaggggtc tttgatgcct
     7021 tattcaattt tggaatcggt acagagctgt ttccattact tatttttatc ggtattggtg
     7081 ccatgattga ctttggtcct ttacttcaaa atcctttcat gctattattc ggtgcggcag
     7141 ctcaatttgg gattttcttt gttgtcgttg tagccgtatt agctggcttt gatattaagg
     7201 aagcagcttc aattggtatc attggtgctg ctgacggtcc aacatcaatt tttgtagcaa
     7261 accaattggc aaaggatttg ctagggccta tcacagtggc agcttattct tacatggctt
     7321 tggttccgat cattcagccc tttgcgatca agctagttac taccaaaaaa gagcgtcgta
     7381 ttcgtatgac ctataaggct gagaatgtgt cacaattaac gaagatcctc tttcctattg
     7441 tgatcacact tgtagccggc tttattgctc caatttcgtt accattggtt ggttttttga
     7501 tgtttgggaa cctgcttcgt gaatgtggtg tcttggaccg attgtcacag accgctcaaa
     7561 acgaattggt caatatcatc agtattttac taggactaac catctctatc aaaatgcagg
     7621 ccgagctttt cttgaatgtg caaaccctgc ttattatcat ttttggtctg ttggccttta
     7681 tcatggattc gattggtggt gtgatgtttg ccaaattctt gaatttattc cgtaaggaaa
     7741 aaatcaaccc aatgatcgga gctgctggaa tttcagcctt tccaatgtca agtcgtgtga
     7801 ttcaaaaaat ggccactgat gaggatccgc agaatttcat cttgatgtat gctgtgggtg
     7861 ctaatgtatc tggtcaaatc gcctcagtta ttgcaggtgg cttgctgctt gcttacttta
     7921 gctaagaaag gacgtgctta tgacaatcaa tatagaccat ttgatccaat cctttgagct
     7981 aatggcactt ggaatggcag gagtatttgt tgtattagga attctctata ttgtagcaga
     8041 ggctctgatt aagctatttc cagtagaaaa ataatagaat atgatctaaa caaggaggtc
     8101 aatcaaatgg agatcaaaca aattgctgtt gctggttcgc ttgaatctag cgacatgatg
     8161 ataacaatat cacctaatga tggtcaggga atcgttttgg aattggattc aagcgttgaa
     8221 aaacaatttg gcaatcatat cagagcatta atcaagacaa cacttgccag gctgggcgtt
     8281 gagtcagcaa cgatcgaagc tgttgataag ggagccttgg attgtaccat tcaggcaaga
     8341 acaattgcag cagtccatcg tgctgctgga gttgagcatt acaactggaa ggagatcgac
     8401 tcatggaacg cttaagaaga acgatgatgt ttgttccggg cgctaatgcg gctatgctaa
     8461 gagatgcacc cttgtttgga gcggactcta tcatgtttga tttagaggat tcagtttcct
     8521 taaaagaaaa agacacctct cgcgcccttg ttcattttgc cctaaaaacc tttgattatt
     8581 caaatgttga gacagttgtg cgcgttaata gcctagactc ttgtggtgct ctggatattg
     8641 aggcagttgt gttagcaggt gttgatgtta ttcgcttgcc aaagacagaa actgcccagg
     8701 atattattga tgttgaggca gtcattgagc gtgttgagcg tgacaatggg attgctgttg
     8761 gtcgtacacg catgatggca gctatcgagt ctgcagaagg ggtcttaaaa gctcgtgaga
     8821 ttgcaaaggc ctcaaatcgt ctcattggta ttgccctcgg cgcagaggat tatgtgacta
     8881 atatgaaaac acgtcgctac ccagatggac aagaattatt ctttgcccgc agcatgattc
     8941 ttcacgcagc acgtgctgct gggattgcag caattgatac cgtttattca gatgtcaaca
     9001 atacagaagg cttccaagct gaggtgcgtc atatcaagca attaggcttt gatggtaaat
     9061 ctgtcatcaa ccctcgtcag attccattgg taaatgagat ttatacacca accgaaaaag
     9121 agattagtca cgccaagcaa gtgatctggg ccattcgtga ggctgaaagt aagggatcag
     9181 gtgtcatttc attaaatgga aaaatggtag ataagccaat cgtagagcgt gcacagcgtg
     9241 ttatcgcttt ggcaacagct gctggggtat taacagagga ggacatttag catggttaaa
     9301 aataaacttg gtcgtgatat tcctcaggag tatgctgatc actatggagt atttgaagga
     9361 gagctagcac gtatcactag ctacaatgaa tcaagccgcc gcattaagcc tgtaaagcca
     9421 ggtgacagta aattgcttgg ctctattcgt gaagctattg aaaagacagg cctaaaagat
     9481 ggcatgacca tttcatttca ccatcatttt cgtgaggggg acttcgtcat gaatatggtt
     9541 cttgatgaga tagccagcat gggaatcaaa gatttagcta ttgctccaag ctctattgcc
     9601 aatgtgcatg agccattaat tgagcacatt aaaaacggag tggttacaag cattacctca
     9661 tcaggtttac gtgataaggt tggggcagct atttcatcag ggattatgga aaagcctgtt
     9721 gtgattcgtt ctcatggagg acgtgctcgt gcgattgcta gtggtgatat tcatattgac
     9781 gttgcctttt taggagcacc aagctcagat gaatatggta atgtcaacgg tacgattggt
     9841 aaggctacct gcggctcact tggctatgct atgatcgatg ccaagtacgc agatcaggtg
     9901 gtggtgctga cagatcacct agttgattat cctaacaccc caattagcat tccgcaaact
     9961 gatgttgatt atgtcgtgac agttgatgct attggtgatc cacaaggaat cgctaaggga
    10021 gcaacgcggt tcaccaaaaa tcctaaggag ctcctaattg ccgaatatgc cgctaaggtt
    10081 atcacacagt cgccttactt taaaaatggc ttttccttcc aaacaggtac aggaggagct
    10141 tccttagcag tgactaggtt catgcgtgag gccatgcttc aagaaaatat caaggcaagc
    10201 tttgcccttg gaggcattac aaacgctatg gtagaattgc tcgaagaagg attagttgag
    10261 aaaatcctag atgtacagga ttttgattac ccttcagcag tttcgcttgg taaaaatgct
    10321 cagcattacg aaattgatgc taacatgtat gcctcaccac taagcaaggg atcggttatc
    10381 aatcaattag acacctgtat tttatcagcg cttgaggttg acactaattt caatgttaat
    10441 gtcatgacag gttctgacgg tgttattcgt ggggcttccg gagggcattg tgacacagcc
    10501 tttgctgcca aaatgagtct ggtgatttca ccccttatcc gcggacgcat tccaaccttt
    10561 gtagatgagg taaatacagt aattacacct ggaacaagcg ttgatgtggt tgtcacagaa
    10621 ataggtattg ctatcaatcc aaaccgtcca gatttgatag agcatttcaa ggacttgaag
    10681 gttcctcaat ttagtatcga agaattaaaa gaaaaggctt actcgattgt tggaacacct
    10741 gatcgtatcc aatacggtga taaggttgta gctcttattg agtatcgtga tggcagcctg
    10801 attgacgttg tctacaatgt ctaaggaatt gattttcaag gggaaagctg ttaccctagc
    10861 tgatatgcta agggcacgcg aggacagaag ccttcgtcaa ggaaagcttt taacagaatt
    10921 ctcaaacgaa agcctgcttt ctgtgaccat gaatattcca ggccccatta aaacgtcacc
    10981 tgctttactt gaggtatttg atagtgttat caaggcaatc ctagaaaagc tgtctggcaa
    11041 tcagatcagc tatcagcttc gtttgctgcc aaaaacgggt tatgaatatt accttgtgac
    11101 agccttagat agtcaggcat taaagctcaa aatgattgag cttgagactg atttaccgat
    11161 tggcaggcta atggatttgg acgttttagt gctgacaaat cagctgccaa cccctatcag
    11221 tcgaacagcc ttaggctttc ctcctcgcag ctgctatctt tgctcaaaag aggctaaggc
    11281 ttgtagtaga aatcgcagtc actcggtagc agacatgcag acagcccttg tacacttact
    11341 ccaatcattt tttgacggag gcaatcagct cagttagact caacggtatt cttataagga
    11401 gaatgatatg acaaaaatcc gtataacaga aacagttttg cgtgatggtc agcaaagtca
    11461 aattgctacc cgcatgacta caaaggaaat gattccgatt ttagaaacac tagataatgc
    11521 tggctatcat gccctagaaa tgtggggagg agctaccttt gattcttgcc tacgtttctt
    11581 aaatgaagac ccttgggagc gtctaagaac cattcgtaaa gtagtcaaga aaactaaatt
    11641 acaaatgctc ctgcgtgggc aaaatctttt gggctatcgt aattatgctg acgatgtcgt
    11701 ccgcagcttt atccaaaaat caattgaaaa cggtattgat attgtgcgca tttttgatgc
    11761 cctaaatgat ccacgtaatc tagagacagc tgtttcagca acaaaagaat tcggtggcca
    11821 tgcacaggtt gctatttctt acacaacaag tccagttcat actatcgatt attttgtagc
    11881 cttagcaaaa gcctatcagg ctattggtgc agattcgatt tgtatcaagg atatggctgg
    11941 tgtgttaacc ccggagaccg gttatcaatt agtgaagcgt atcaaggaaa gcattgctct
    12001 accacttgag gttcacacgc atgctaccag tggtatttct gaaatgacct atctcaaggt
    12061 cgtagaggct ggtgcagata ttattgatac tgccatatcc tcatttgccg gcgggacaag
    12121 ccagccagca acagaatcga tggttattgc tttagaggac ttggggattg ataccggagt
    12181 agacatgaca aggctgacaa aaattgccga gtattttaat actatccgag atcactacag
    12241 ggcagagggc attttaaatc ccaaggttaa agacactgag cctaagacct tgctttatca
    12301 ggttcctggc ggcatgctgt ccaatttgct aagtcagctt aaggaacagg gactctctga
    12361 caaatatgaa gaggttctgg ctgaggttcc aaaggttaga gctgatttag gctacccccc
    12421 actggtgact ccgctatcgc aaatggttgg cacacaggcc ttaatgaatg ttatttcagg
    12481 tgaacgctac aaggttgtcc caaacgaaat caaagactat gtcagaggac tttatggcca
    12541 acctcctgcg ccactaggtg aaggtattaa agagaaaatc attggtgatg aagctgttat
    12601 cacttgtcgt ccagcagatt tgattgagcc acaattgccc ttgcttcgtc aagaaattgc
    12661 aggctatgcc tgctgtgagg aggatgtgct gagctatgcc tctttccctc agcaggcaaa
    12721 ggatttccta ggacgcagag aggatccctt ttatgatatc ccagttcagt acgtcaccgt
    12781 tgatatagca atggattaat caaaagaata aaaagcaaga taactaataa aatcaatctc
    12841 ctaattatta gtcaaagcta cctaccaata aactccttaa tcagaaccac ccgtctaatg
    12901 aggtgccccc aaaaggttag tccaaaactt taggctccat gtcaactgta gtgggtagtt
    12961 gacaagctaa catctggaga ggac
//
LOCUS       DARYNN010000054        12821 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.054, whole genome shotgun sequence.
ACCESSION   DARYNN010000054 DARYNN010000000
VERSION     DARYNN010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12821)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12821)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12821
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.054"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            161..835
                     /locus_tag="TVB59_001645"
     CDS             161..835
                     /locus_tag="TVB59_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1010515.1"
                     /translation="MQNEKELQITLRNVSKKYGEHSILENISLDIYKGDFVCIFGKSG
                     GGKTTLLNIIGTLENYDSGSVTCFSNRDPIKAPKVGELLRREKIAYLFQNFALVEKMT
                     VEENMMLAAKYNQEKNKKNLIEAALNKMGISDKLKSKVYELSGGEQQRVALARNMIKP
                     FEIMLADEPTGSLDYENKKIVIDTLIRLNDEGKTIVVVSHDKDFEKVAHKNYIIEKSA
                     IREVLR"
     gene            832..1428
                     /locus_tag="TVB59_001646"
     CDS             832..1428
                     /locus_tag="TVB59_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1010516.1"
                     /translation="MKRKIALLVPVIVLCICGLFFYMNRNSDDIDVAFTVKNETKEKI
                     DTVGIAMGNKCILNRTNGEKFYFPKDLIKEKQGKAIVFVVSKDGIIAKSGEIDLKENK
                     EVSIREIKEGEISLDIAAQKTDIKISIPRLDDWKVSTDEKFIKGSYEANTDSQYTLYL
                     LGKGGNLGISGTEMKGVRVIVSWEKPKDKIDSWLVFND"
     gene            1786..2001
                     /locus_tag="TVB59_001647"
     CDS             1786..2001
                     /locus_tag="TVB59_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002838961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family protein"
                     /protein_id="HEL1010517.1"
                     /translation="MDFFVQAVNVLKILVMAIGAGLGAWGVINLLEGYGSDNPGAKSQ
                     GIKQLMSGGGIVLIGLKLIPLLANVLR"
     gene            2001..2864
                     /locus_tag="TVB59_001648"
     CDS             2001..2864
                     /locus_tag="TVB59_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010518.1"
                     /translation="MFDLFGKIEEFFKDIMIDIIKDNLSAMLVDINDKVGTVAGEVGK
                     TPSSWNSEVFTFIKSINTNVVLPIAAIILTAILCIELIQVVMRKNSMHDTDTFEFFKY
                     IIKMWIAVWLVSHAFDFSMAVFDVAQSMIGKAAGVVGTSANITPGNFDAMVEALKTKE
                     LGTLIGIALETGLVKFSLTILSILITVILYGRMIEIYIYCSVAAIPFSTMGNKEWSNI
                     GTNYIKSLFALGLQGLFILIFFGIYAVLVKTVNFTDIHTSILQVLAYGLILGVMMMKS
                     GSIAKAILNSH"
     gene            2937..3431
                     /locus_tag="TVB59_001649"
     CDS             2937..3431
                     /locus_tag="TVB59_001649"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1010519.1"
                     /translation="MNKINKKTRILIGAGSALSIGTIITVLLKKKTKKLSDLEEDDFD
                     FDFDEIEEDSCVNDKFATENDKDDTVKGEIDFLVDESKTENEKQEEFRDLSVKVMDLL
                     LKEVISMSETLNLVKRDIDRIGEVKALVEELENCKEEIISLWEHMEKLSDLREEITGK
                     KNRG"
     gene            3435..3845
                     /locus_tag="TVB59_001650"
     CDS             3435..3845
                     /locus_tag="TVB59_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009531364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HEL1010520.1"
                     /translation="MAYVKIPKDLTKVKTKVALNMTKRQLIGFSIAGLIGFPVYMLCK
                     NFLSTDISMIIMSIVVLPVLFVTLYEKDNLPFEKHLAYILRFHKSKKIRLYKARSIYH
                     TERAKKQDIGNKNKASGRRKKVEQRQKKKTGTTN"
     gene            3805..6282
                     /locus_tag="TVB59_001651"
     CDS             3805..6282
                     /locus_tag="TVB59_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HEL1010521.1"
                     /translation="MNKDKRKKQEQRIKKDELELRKNRKELSELKKTGKKKTKSKTKG
                     KSSKKNGWFPFFMKEEKKETVQDTIPYKRMLKDGICQIEKNKFNKTIRFLDINYRLME
                     EIDQEGIFSEFSSFLNFFDSSVEVEFSYINSIGENEEINKLIDIKENIDDFNEIRNEY
                     RQMLLNQSSKGNNGLSKSMYITFTIEAEDLKQAKSRLERMEMDVLNNFKQMGVKAYVL
                     DGEERLKTIHDILNPNDKLVFSFEDLKYSGLTTKEYIVPPSFNFSKPTYFKTGEVFAE
                     VNFLQLLASDIKDEMLSEFLALEENMIVTFHIRAIDQMEAIKHVKRKITDLDKMKLEE
                     NKKAIRAGYDMDILPSDLVTYGAEAKNLLSELQNHDEKMFLITILFMNTSKSKGKLDN
                     TVFTLKSIANRHNCSLKNLNYRQEQGLVASLPLGINEVEIERGLTTSAAAIFIPFTTE
                     ELFIKGESLYYGLNALSRNIIMADRKKLKNPNGLILGTPGSGKSFAAKREITNAFLIT
                     DDDIIIADPEAEYSPLVEALKGQVIRISPISKDYVNPLDINIDYADEDNPLSLKSDFI
                     LSLFELVVGEKKLSAEEISVIDRCLPILYKTYFENPVPENMPILEDLYNLLQKQEEIV
                     GKKLAVEMEIYVKGSLNVFNHRTNVDTNNRVVCYDIKELGKQLKKIGMLVVQDQVWNR
                     VTINRASKKATRYYVDEFHLLLKEPQTANYSIEIWKRFRKWGGMPTGLTQNIKDLLAS
                     PEIENIFDNTDFILMLNQAGTDRDILAKKLNISKHQLSYVTNSGEGEGLIFYGNTIVP
                     FIDQFPKNTKLYSLITTKPEEVKKAGE"
     gene            6284..7309
                     /locus_tag="TVB59_001652"
     CDS             6284..7309
                     /locus_tag="TVB59_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEL1010522.1"
                     /translation="MSVSRSKEEFIKENTNKIICSDALETLRKIPDESISCCITSPPY
                     YRLRNYHKEGQIGRESTVEEYLDRLLQVFREVRRALKKEGTCFIVIGDSYADSGGGKG
                     QYIDPKYPKARNGSNALATENISGYKSKDLMGIPWRLALLLREDGWYLRSDIIWHKEN
                     AMPEACRDRPTRSYEHIFLLTKSPKYYYDYDAMVEPMKEVSKKRYVRGRKSDNKYLKE
                     NSGAKLQKINEARKYGEYKGDNVPQFRNKRDIWTINTTSFRGNHYATFPPKLVEICMI
                     AGCPKNEIVLDPFIGSGTVGFVALRHNRKYIGIELNEEYVNLAKNRISEEVKKFNEEQ
                     KQEVQKE"
     gene            7275..9563
                     /locus_tag="TVB59_001653"
     CDS             7275..9563
                     /locus_tag="TVB59_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL1010523.1"
                     /translation="MKNKNKRYKKNREKLLNQEIQSLQSQTQDNYETGSSKNQNETLL
                     KDETYDKKQFLSEKKLSNHLDNRHINNYSDRTISSYCLSDTGNINQNRSSFQAEKHKK
                     KMQKQINKFQKGEKEVYDPLSKDMDNDGVIDRYDVDFRDSKVSYRTLTDDEKYDNNQN
                     DKGKNYNDYVKNPKSKNKRYKNYVKDTFSKERMKSENQKKYVRSNFDDEEFTRNKDTK
                     NNLFQDVNNKRKTTDKNSSRKRKGKFENKEKKISKLQQKKQRQEQKLKNKGIDGKSQS
                     AKSAVIATGMAKRYLESGKEDNAGVGTAYKVTDQVENISRKIYYHGKKKNLKRQKKIT
                     KLGKSIDKQEKKLFFQKNMEEMKKSVDYQNTSRLRQFFKRRQYKNQIQKKYKDSVKNR
                     IKKSFIEGSKRFGEFVKGRGKKIIFLSLLAVGIFFMLFQAGSMMMNMGTGMVSNTVST
                     TYLSSEDTLKEINQRFSSLEQALQEEMDSVEENHPGYDEYIIKGKEKIGHNVHELLSY
                     ITARYGIVKNISEVESELKHLFQKMYTLTYKEEIEIRYRTVTSSYTDADGNEHTESHE
                     EPYEYRKLIVTLEKREMDGIIREAFKRYPNNLAHYETLFLTQGNMGEVFGNIDLINSN
                     GGIGGGKEYEASSEVQKKIVNAAYITPSPGAGWCAMWVSQVYQNAGLGFIGGNACDMY
                     RNYTFTSDRSKLKVGMLVAVESSSSGSSLGVTYGHVGIYIGDGKVMDNIGHIRVTTLD
                     DWIATFCKHHPVGFGFPPSVQK"
     gene            9576..9863
                     /locus_tag="TVB59_001654"
     CDS             9576..9863
                     /locus_tag="TVB59_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009530021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1010524.1"
                     /translation="MNKKYRKNIEKQKDIQKKIEELQLKQEMLKEEQEEMENIEVLKE
                     YRSIDISIDDFLEMMRRYKKEEKQEKMKLQEMRNTENHNNMEENHENQMEE"
     gene            9841..11303
                     /locus_tag="TVB59_001655"
                     /pseudo
     CDS             9841..11303
                     /locus_tag="TVB59_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679624.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
     gene            11556..12149
                     /locus_tag="TVB59_001656"
     CDS             11556..12149
                     /locus_tag="TVB59_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005956659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HEL1010525.1"
                     /translation="MNYENKIEKYLKQSGGIITTAYCKENNIPTIYLSRLLKDGRLSK
                     VRKGIYITKDGDYDEYYFFQHQYKKAIFSYETALYLLGQTDKIPWSIDVTVYNGYKFN
                     EKPNGFNVHYVKKSIYDLGVTQKPTMFGNKVKVYSYERTLCDFIAHKEEMDIEVYVKL
                     IQSYSSYKERDIHSLYDIAMKMGIENKVREVMEVAYE"
     gene            12142..>12821
                     /locus_tag="TVB59_001657"
     CDS             12142..>12821
                     /locus_tag="TVB59_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HEL1010526.1"
                     /translation="MNKAKLTALCHKVSKEVGLSFNAVMLYYFLESILKKLAGSKYSE
                     RFIFKGGFLLSSVVGIDSRSTVDIDFLLRNMQLSEENIVQMLNETLKPEEFDDIFYEL
                     QNIVPIKEEDQYGGFRANILCKMENIRQIVPLDIATGDVITPHPIDYKYVSSFGEEEI
                     IIKAYPIETMLAEKIQTIYARGFLNSRSKDYYDLYIIYKLKDKDVNVEILREACRKTF
                     SYRKTEFD"
BASE COUNT         5133 a         1552 c         2639 g         3497 t
ORIGIN      
        1 tgttggactg tttataccaa gagatggttg gagtatgtct aaacttttga ttagtttaat
       61 aataggtatt tgtggaagct ttatatgttt tggcatagaa attttacaac taaagaaaag
      121 tgaaagaagc attgtactta ggttaaagga gggttgttaa atgcaaaatg aaaaggaatt
      181 gcaaataacc ttaagaaatg tctctaagaa atatggagaa cacagtattt tggaaaatat
      241 tagtttggat atttataaag gagattttgt ttgtatcttt gggaaaagtg gaggaggaaa
      301 aacaacactt ttaaatataa ttgggacatt agaaaattat gatagtggta gtgtaacctg
      361 tttttcaaat cgagatccta taaaagctcc taaagtagga gagctattac gcagagaaaa
      421 aattgcttat ttatttcaaa attttgcttt ggtggaaaaa atgacggttg aggaaaatat
      481 gatgcttgct gcaaaataca atcaagaaaa aaataagaaa aatcttatag aagctgcctt
      541 gaataaaatg ggcatttcag acaaattaaa atcgaaggtt tatgaacttt caggtggaga
      601 acagcaaagg gtagctcttg caagaaatat gataaaaccg tttgaaatta tgttggcgga
      661 tgaaccgaca ggttctcttg attatgagaa taaaaaaatt gtaatcgata cacttattag
      721 attaaatgat gaaggtaaga caatcgtagt tgtaagtcat gataaggatt ttgaaaaagt
      781 agcacataag aattatatta ttgaaaagtc agctataagg gaggtgttga gatgaaaagg
      841 aagattgctt tattagtacc ggttatagta ctgtgtattt gtggtttatt cttttacatg
      901 aacagaaata gtgatgatat tgatgttgca tttacagtaa aaaatgaaac aaaagaaaaa
      961 atagatacag tgggtattgc gatgggaaat aaatgtattt tgaatagaac aaatggagaa
     1021 aaattttatt ttccaaaaga cctaatcaaa gaaaaacaag gcaaagctat tgtttttgta
     1081 gtatctaaag atggaatcat agcaaagtca ggggaaatag atttaaaaga aaataaagaa
     1141 gtaagtataa gggaaataaa agaaggagaa atatccttgg atatagctgc tcaaaaaaca
     1201 gatataaaaa ttagtattcc taggttagat gattggaaag ttagtacaga tgaaaaattt
     1261 atcaagggct cttatgaagc aaatactgat tcgcaatata cattatattt attaggaaaa
     1321 ggcggaaatt taggcatttc cggtacggag atgaaaggag tacgtgttat tgtaagttgg
     1381 gaaaaaccaa aagataaaat agatagttgg cttgtattta atgattaaaa atacaatatt
     1441 tgtaataaaa gttgtaaaat aataatttat tgttagggga ggatttatac taatgtgtaa
     1501 atcctctttt ttatataaag cataaaataa tgaaagtgaa attaagctat aaaatattat
     1561 gaaaaaagat acttggaagt gtaaatgtaa gatgtatatt tctaaaaata atagacatta
     1621 atttaaaaga gagatgggat aaataaaatg aaaaatataa taaaatcaat aaggataaga
     1681 agtccaactt taagaaaatt gaatagcaaa agtttaacga ttggaagaga agatttccag
     1741 tcgttttttt atgaaaataa gtaaaataat gaggaggaat aaattatgga tttttttgta
     1801 caggcagtaa atgtgcttaa aattttggtt atggcaatcg gtgcaggact tggtgcatgg
     1861 ggagttatca acttacttga aggatacgga tcagataatc ccggtgccaa gtcgcaagga
     1921 atcaagcaat tgatgagcgg tggaggaatt gttttaatag ggctgaaact aattccgcta
     1981 cttgctaatg tcttgagata atgtttgatt tatttggaaa gatagaagag tttttcaagg
     2041 atattatgat tgatattatt aaagataatc tttctgcaat gcttgtggat attaatgata
     2101 aagtaggaac cgttgcagga gaagtgggaa agactccgag ttcttggaac tcggaggtct
     2161 tcaccttcat taaatcaatc aataccaatg ttgttttacc catagcagcg ataattctaa
     2221 ccgcaatact ttgcatagaa ctgattcagg tggtaatgag aaaaaattct atgcacgata
     2281 cggatacctt tgaatttttt aagtacatta ttaaaatgtg gatagctgta tggcttgtgt
     2341 ctcatgcgtt tgatttttca atggcagtct ttgatgtggc acagtccatg ataggaaagg
     2401 cagcaggtgt tgtggggaca agtgcgaata tcacaccggg aaattttgat gctatggtag
     2461 aagcccttaa aacaaaggaa cttggaacac tcattgggat tgcactggag acgggattag
     2521 ttaaattttc tttaacgatt ctatcaatct taatcactgt aatcctatat ggaagaatga
     2581 ttgagatata tatctattgc tctgttgcgg caattccatt ttctacgatg ggaaataaag
     2641 aatggtcaaa tatcggaaca aactatataa aaagtctatt tgcccttgga cttcagggac
     2701 ttttcatcct aatatttttt ggaatttacg cagtcttagt caaaaccgta aactttacgg
     2761 atatccacac aagtatttta caggtattgg catatggatt gattcttgga gtaatgatga
     2821 tgaaatccgg aagtatagca aaggcgattt taaacagtca ctaaaggact ttagttcaaa
     2881 atgagcaaaa gttgatgaaa taatcagaac aaaaaatata attattggag gtaagaatga
     2941 ataaaataaa taaaaaaaca aggattttga taggagcagg ctcagccctt tctatcggga
     3001 caattattac agtgctatta aaaaagaaaa cgaaaaaatt atccgatctt gaagaagatg
     3061 attttgactt tgattttgat gaaatagaag aagattcttg tgtcaacgat aaatttgcta
     3121 cagaaaatga taaagatgat acagtaaaag gagaaataga ttttttagta gatgaatcaa
     3181 agacggagaa cgaaaagcaa gaagagttta gagatttatc ggtaaaggta atggatcttc
     3241 ttctaaaaga agtaatttca atgagtgaaa ccttaaattt ggtaaaaaga gatattgata
     3301 gaataggtga agtaaaagca ttggttgaag aactggaaaa ctgtaaagaa gaaattatct
     3361 cactttggga gcacatggaa aagttatccg atttaagaga agaaattacc ggcaaaaaga
     3421 atagaggtta ggctatggct tatgtaaaga taccaaaaga ccttacaaaa gtaaaaacca
     3481 aggtagccct gaatatgaca aaaaggcagc ttataggttt tagcatagca gggcttatcg
     3541 gttttcctgt atatatgctg tgtaaaaatt ttcttagtac agatatttcc atgattataa
     3601 tgagtatagt agttctacct gttctttttg taacgcttta tgaaaaggac aatttacctt
     3661 ttgaaaaaca tttagcatat atcctcaggt ttcataaaag taaaaagatc aggctatata
     3721 aagcgaggag catttatcat acagagagag caaaaaagca agatatagga aataaaaata
     3781 aggcaagcgg aaggaggaaa aaagttgaac aaagacaaaa gaaaaaaaca ggaacaacga
     3841 attaaaaagg atgagttgga gcttaggaaa aatagaaagg agctatccga acttaaaaaa
     3901 acaggaaaga aaaaaacaaa gtctaaaaca aaagggaaat catcgaagaa gaatgggtgg
     3961 tttccttttt ttatgaaaga ggagaaaaaa gaaaccgtac aggataccat tccatataag
     4021 cgaatgttaa aagacgggat ttgtcaaatt gaaaagaata agtttaataa aaccattcga
     4081 tttttggaca ttaactatcg cttaatggaa gaaatagacc aagagggaat attttcggaa
     4141 ttttcttctt ttctaaattt ctttgactca tctgtggaag tggagttcag ctatatcaac
     4201 agtatcggag aaaatgaaga aatcaataaa ctgattgata ttaaggaaaa tatagatgat
     4261 tttaatgaaa ttagaaacga atatagacaa atgctcttaa atcaaagcag caaagggaat
     4321 aatggattat caaagagtat gtacattacc tttaccatag aggcggagga cttaaagcag
     4381 gcaaaaagta gattagagcg aatggaaatg gatgtattaa acaactttaa gcagatggga
     4441 gtgaaagcct atgtgttaga tggagaggaa agacttaaaa caattcatga cattttaaat
     4501 ccaaatgata aacttgtttt ttcctttgag gatttgaaat acagcggact gacgactaag
     4561 gaatacattg tacctccgtc ttttaacttt tccaagccga cgtattttaa gacaggagaa
     4621 gtctttgcgg aagtaaattt tttacagctt ttagcatcag atattaaaga tgagatgtta
     4681 tcagagtttt tggcattgga agaaaatatg attgttactt ttcatatcag agcaatcgac
     4741 cagatggaag ctattaaaca tgtaaaaaga aaaataacgg atttggataa gatgaagctt
     4801 gaggaaaaca aaaaagctat tcgtgcggga tatgatatgg atatcttgcc aagcgacctt
     4861 gtaacttatg gtgcagaggc aaagaacttg ctatcagaac tacaaaacca tgatgaaaag
     4921 atgtttctca taacaatttt atttatgaac acgagtaaaa gtaaggggaa actcgataat
     4981 acggtattta ccttaaagtc cattgcaaat agacataatt gtagtttgaa aaacctaaat
     5041 tatagacaag aacaagggct tgttgcaagc cttccacttg ggataaatga agtggagata
     5101 gaacgaggac ttaccacaag tgcagcagct atttttatac catttacaac agaagaactc
     5161 tttatcaagg gagaaagcct atattacgga ctaaatgcac taagcagaaa tattattatg
     5221 gcggacagga agaaattaaa gaacccaaat ggtctaatct taggaacacc gggttctgga
     5281 aagtcctttg cagccaaaag agagattact aatgcgtttt tgattacaga tgatgatatt
     5341 atcattgcag atccggaagc ggaatattct ccgcttgtag aggcactaaa aggacaagtt
     5401 atcagaattt ctccgatttc aaaagactat gtcaatccac tggacatcaa tattgactat
     5461 gcggatgaag ataatccttt gtctttaaaa tccgacttta ttttgtccct atttgaattg
     5521 gtggttggag aaaagaaatt aagtgcagaa gaaatttctg ttatagaccg ttgtttacca
     5581 attttatata aaacctactt tgaaaatcct gtgccggaaa atatgccaat tttagaggat
     5641 ttatataatc ttcttcaaaa acaggaagaa atagtaggaa aaaagcttgc agtagaaatg
     5701 gagatctatg taaaaggaag tcttaatgta tttaatcata gaacgaatgt agatacaaat
     5761 aacagagtgg tttgctatga catcaaagaa ctgggaaaac agcttaaaaa gataggaatg
     5821 ttagttgtgc aggatcaagt ttggaataga gttacaatta acagagcaag taaaaaagca
     5881 accagatatt atgttgatga atttcatctt ttgttgaaag aaccgcaaac agccaattat
     5941 tcgattgaaa tctggaagcg tttcagaaaa tggggtggta tgccaacagg acttactcaa
     6001 aatatcaaag accttcttgc aagcccggag attgaaaata tttttgataa tacggatttt
     6061 attttaatgc ttaatcaagc aggaacagat agggatattt tagccaagaa gctcaatatc
     6121 tccaagcatc agctttctta tgtaacaaat tcgggggaag gagaaggact tatcttttat
     6181 ggaaatacga ttgttccttt tatcgatcag tttccaaaaa atacaaaact atattcacta
     6241 atcacaacca aacctgaaga agtaaaaaag gcaggtgaat aggatgagtg tgagcagaag
     6301 taaagaggaa ttcatcaaag aaaatacaaa taaaattatt tgttcggatg cacttgaaac
     6361 tttaagaaaa attccagacg aaagtataag ctgctgcatt acatctcccc catactacag
     6421 gctcagaaac tatcataaag aaggtcagat aggaagagaa tctacagtag aagaatactt
     6481 ggatagattg ttacaggtat ttcgtgaagt aagaagagct ttaaaaaaag aaggtacttg
     6541 ctttatcgta attggagatt cttatgctga ttcaggaggt ggaaagggac aatacattga
     6601 tcctaaatat ccaaaggcaa gaaatggaag taacgcttta gctacagaaa atatctcagg
     6661 gtacaagtca aaagatttaa tgggaatacc ttggagatta gcgttacttc taagagagga
     6721 tggttggtat ctgcgttctg atattatctg gcataaggaa aatgctatgc cggaggcgtg
     6781 tagagataga cctactcgtt cctatgaaca tattttttta cttacgaaat caccaaaata
     6841 ctattatgac tatgatgcta tggtagagcc gatgaaagaa gtcagtaaaa aaagatatgt
     6901 aagaggaaga aaatcggata ataaatatct gaaagaaaat tccggagcaa agttgcaaaa
     6961 aatcaatgaa gcaagaaaat atggagaata taagggcgat aatgtcccgc agtttcgtaa
     7021 taaaagagat atttggacta tcaataccac atcttttaga ggcaatcatt atgcaacatt
     7081 tccaccgaaa cttgttgaga tttgtatgat tgcaggttgt cctaaaaatg aaattgtact
     7141 tgatcctttc attggaagtg gaacggtcgg atttgtggca cttcgtcata acagaaagta
     7201 cattggaatt gaattaaatg aggagtatgt aaatcttgca aagaatagaa tcagtgagga
     7261 ggtgaaaaaa tttaatgaag aacaaaaaca agaggtacaa aaagaataga gaaaaactct
     7321 taaatcaaga aatacagtct ttacaatctc aaactcaaga taattatgaa acaggatcct
     7381 caaaaaatca gaatgaaacc ttgctgaaag acgaaactta cgataagaaa caatttttat
     7441 ctgaaaagaa gttatccaat catttggata atagacatat aaataattat tcggatagaa
     7501 ctatatcttc ttattgcttg tcggatacgg gaaatataaa tcaaaatagg tcttcctttc
     7561 aagctgaaaa acataaaaaa aagatgcaaa agcagataaa taaatttcaa aagggagaaa
     7621 aggaagtcta cgatccttta tcaaaagata tggataatga tggtgtaata gacaggtatg
     7681 atgtggattt tagggatagc aaagtatcat atcgaactct tacagatgat gaaaagtatg
     7741 ataataacca aaatgataaa ggaaaaaatt ataatgacta tgtaaaaaat ccaaaatcta
     7801 agaataagag gtataaaaat tatgtaaaag acacattttc taaggaaaga atgaaatcag
     7861 aaaaccagaa gaaatatgtg aggagcaact ttgatgatga agagttcaca agaaataagg
     7921 atacgaaaaa taatttattt caggacgtaa ataataaaag aaaaactacc gataaaaatt
     7981 catcacgaaa aagaaaagga aaatttgaaa ataaggaaaa gaaaatatcc aagttacagc
     8041 agaaaaagca aagacaagag caaaaactga aaaataaggg aattgacggg aaaagtcaaa
     8101 gtgctaaaag tgcagtaata gcaacgggta tggcaaagag gtatttggaa agtggaaaag
     8161 aggacaatgc cggagtaggt actgcttata aggttacaga tcaggtcgaa aatatttcaa
     8221 ggaaaatata ttatcatgga aaaaagaaaa atttaaaaag gcaaaaaaag ataacaaaat
     8281 taggtaaaag cattgataaa caggagaaga aactcttttt tcaaaagaat atggaagaga
     8341 tgaaaaaaag cgtggattac caaaatacct caaggctcag acaattcttt aagagaaggc
     8401 aatataaaaa tcagattcaa aagaagtata aagatagtgt gaaaaacaga ataaaaaaat
     8461 cctttataga gggcagtaaa agatttggcg aatttgtaaa gggcagaggg aaaaagataa
     8521 tatttctatc acttttagcg gtaggaatat tttttatgtt atttcaggct gggagcatga
     8581 tgatgaatat gggaacggga atggtaagta atactgtttc aaccacctac ttatcatcag
     8641 aagacacctt aaaagaaatc aatcagaggt tttcatcttt ggaacaggct ttgcaagaag
     8701 aaatggacag tgtggaggaa aatcatccgg gctatgatga atatattatc aaaggaaaag
     8761 agaaaattgg tcataatgtt catgaactct tgtcatatat cacagcccgt tatggaattg
     8821 taaagaatat ttctgaagta gaaagtgaac taaaacatct gtttcaaaaa atgtatacgc
     8881 tgacttataa agaagagatt gaaatcagat atagaactgt tacatccagc tatacggatg
     8941 ctgatggcaa tgaacatact gaaagtcatg aagagccgta tgagtatagg aaactcattg
     9001 taaccttaga aaaaagagag atggacggaa ttattagaga agcatttaag cgttatccta
     9061 ataatttggc acactatgaa actttatttt tgacacaagg aaatatggga gaagtatttg
     9121 gaaatattga ccttataaat tcaaatggtg gaattggtgg tggtaaagag tatgaagcat
     9181 caagtgaagt gcaaaagaaa atagtgaatg ccgcttatat tacaccatct ccaggagcag
     9241 gttggtgtgc catgtgggta tcacaggtct atcaaaatgc aggacttgga tttattggag
     9301 gaaatgcttg tgatatgtat cgaaattata cttttacttc tgataggtca aagttaaagg
     9361 ttggaatgct tgttgcagtt gaaagtagca gtagtggtag cagtttaggt gttacctatg
     9421 gtcatgtagg tatttatatc ggagatggaa aagtaatgga taatatcgga cacataagag
     9481 taactaccct agatgattgg attgcaacat tttgcaaaca tcaccctgta ggttttggat
     9541 ttccaccatc agtacaaaaa taaggaggga atattttgaa taaaaaatat agaaaaaata
     9601 tagaaaagca aaaagatatt cagaaaaaaa tagaagaact ccagttaaaa caggagatgt
     9661 taaaagaaga acaggaagag atggaaaata ttgaggtttt aaaggaatac cgaagtattg
     9721 acatttctat tgacgatttt ttagaaatga tgagacgtta taaaaaagag gaaaaacaag
     9781 aaaaaatgaa gttacaggaa atgagaaata cagaaaatca taataatatg gaggaaaatc
     9841 atgaaaatca aatggaagaa taaaaaaatg gcgataacat tgtccggagt aatctttttg
     9901 atacttgctt tacttggaac aatgcttttc aatcaccaga ttgtttttgc acaaggtagt
     9961 ttaatcccga cactgattag tcccacagaa gttttagctc aaactaaagt ggaggttaag
    10021 ataaaatata tatttaagga tgagagtgta tataaggaag aaataattga agtagaaacc
    10081 gggcaagttc ttgacagtgg ggacctacca atgttagagg ataatatgaa atttattgac
    10141 gaatttttgt tctataaagt aaagggagac ggtacagatg agattatccg taaagtagaa
    10201 aaaattacag ttaaggataa agaaattcag acagaagagg aaaagccaaa acaggacgaa
    10261 agcactgaga cggaagataa aaaacagaag ataagggaac acagacagag ctttctaaag
    10321 atgatatttc caaaatggaa aaagaggcaa aagagcttca ggataaactt gataaattaa
    10381 atggtgaaat cagggataaa gacaaactaa gcgataaaca gaaagaaaaa atcaaagacc
    10441 ttgaagctga gattgaaagt ctgaaagaaa aaatgaagaa agataaggga aataaagact
    10501 tatcagaaga tatgaaaaag gaaatagata agctgacgga aaaggtgaaa gagcttgaga
    10561 aaaagccaac tgaaacaaac aaagctcctg taacatcaca gtctgttaca ccgattagtc
    10621 ctatttcagg gattaagaca agctcaggta tttcttctca aacaccacag agttccggta
    10681 aaggttcatc tgatgcagta agctccggca atactacaaa agatacaggt aaaactgaat
    10741 caaaggagaa agaaaaggaa gttcgctatc ccaataagct gacaccgaaa gctcctgcta
    10801 ataacagtag tcaggattca tcaatggacg gtgcaagtag caatgtaaat accaataagg
    10861 gtgtggcttc agctccgtca aaggcaagag gaactgttac agaaaataaa gataatgcga
    10921 ataatgatta tccaattcat catggggata gcagcgataa caaagaagca gataagtatt
    10981 cagcagatgc aagacaattt attactttcc agacaaaatc cggaaagaca tttcatttaa
    11041 tcatcaatca cgatgagcaa agtgaaaatg taatgctttt gactgaagta tctgaagatg
    11101 atcttctgaa tatggtagag aagaaggaaa acccgcaaga agaaatcaaa aaaatggaag
    11161 aaacggtacc ggaaagcgaa gtaaaaaaag aagagccgaa aaaggaagaa ggtaaaggta
    11221 gcggctcata tattttttta ggaatcatcg ttcttgcagt agttggagca ggatattact
    11281 ttaaaatcta caagaaaaag taggaagatg atgattatga tgaagatgag gaagaatatg
    11341 atgaatttga agatgagtat gaaaaagagg acgatacaga agatttggaa gaaacagtag
    11401 aagaacagca taacatagat gatatggcaa tcgactctta tgatgaagaa gatgaggaat
    11461 aaagttataa aaagagaaat gtaaaccctg atgttgcgtt tacacttaaa aaatggtata
    11521 atgcaagtgt aaacgcaaca aagggggtgg atgggatgaa ttatgaaaat aaaattgaaa
    11581 aatatttgaa gcaatcaggt ggaattatta caacagcata ctgtaaggaa aataatatac
    11641 cgacgatata tctcagtcga ctattgaaag atgggagatt gtcaaaagta agaaaaggaa
    11701 tttatataac gaaagatggg gattacgatg agtattattt ctttcaacat cagtataaaa
    11761 aggcgatatt ttcttatgaa acagcacttt acctgcttgg acaaacagat aaaattcctt
    11821 ggagtatcga tgtaaccgtt tataacggat ataaatttaa tgaaaaaccg aacggtttca
    11881 atgttcatta tgtaaaaaaa tcaatttatg acttaggggt aacccaaaaa cctacaatgt
    11941 ttggaaataa agttaaggta tattcatatg agaggacact ctgtgatttt attgctcata
    12001 aagaagaaat ggatatagag gtttatgtaa aacttattca atcatattcc tcttataaag
    12061 aaagagatat ccattccctc tatgacattg caatgaaaat gggaattgaa aataaagtaa
    12121 gagaggttat ggaggtggct tatgaataaa gctaaattaa cggctctttg ccataaagtt
    12181 agtaaagaag tcggtctttc gtttaatgct gttatgttat attatttttt agaaagtatt
    12241 ttaaaaaaat tagcaggaag caaatatagt gaacgattta tttttaaggg cggctttttg
    12301 ttatcaagtg tagttggaat tgattcaaga agtactgtag atatagactt tcttttgaga
    12361 aatatgcaac tatcagaaga aaatattgtt caaatgctga acgaaacttt aaaaccggaa
    12421 gaattcgacg atatttttta tgaattgcaa aacattgtgc caatcaaaga agaagatcaa
    12481 tatggaggat ttcgtgcaaa tatcttatgt aaaatggaaa atataagaca gattgtacca
    12541 cttgacattg caacaggaga tgttattaca cctcatccga tagattataa gtatgtgagt
    12601 tcttttggag aagaagaaat aataatcaag gcttatccga tagaaactat gcttgcagaa
    12661 aaaatacaaa ctatttatgc aagaggattt ttaaatagta gaagtaagga ttattacgat
    12721 ctttatatta tttataaatt aaaggataaa gatgtaaatg tagagatatt aagagaggct
    12781 tgcagaaaaa cttttagtta tagaaaaaca gaatttgaca t
//
LOCUS       DARYNN010000055        12312 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.055, whole genome shotgun sequence.
ACCESSION   DARYNN010000055 DARYNN010000000
VERSION     DARYNN010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12312
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.055"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(262..465)
                     /locus_tag="TVB59_001658"
     CDS             complement(262..465)
                     /locus_tag="TVB59_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin BlpN"
                     /protein_id="HEL1010527.1"
                     /translation="MTHYYQIKEEELNDICGGNPAGAAVVGGLTCAVGGIKLGSRIGP
                     WGAVIGGVGSAAVCGYLAYKASS"
     gene            complement(482..736)
                     /locus_tag="TVB59_001659"
     CDS             complement(482..736)
                     /locus_tag="TVB59_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEL1010528.1"
                     /translation="MNTTLMKQFNIIDADKLAHIEGGKNNWQANVWEGGTAAVSGWGL
                     GTAICAASGAGAPFMGACGYIGAKFGVSLWAGVTGATGGF"
     gene            complement(1478..1774)
                     /locus_tag="TVB59_001660"
     CDS             complement(1478..1774)
                     /locus_tag="TVB59_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL1010529.1"
                     /translation="MLTQEEILNKVYNLILDPTLTSEERVILVRFKDRVGESSNFDRE
                     VMMLSESLRQLAVKQIRVETMSVEMAKFYKEISTYKECDKQLGRGLISLGVIRR"
     gene            complement(1781..2029)
                     /locus_tag="TVB59_001661"
     CDS             complement(1781..2029)
                     /locus_tag="TVB59_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="garvicin Q family class II bacteriocin"
                     /protein_id="HEL1010530.1"
                     /translation="MNMTLMKQFNIIDADKLAHIEGGGKGICKFVMSGSNGYACRYSN
                     GEWGYIVTKSNFEATKDVIVNGWISSLGGGYFHPGYRG"
     gene            2289..4445
                     /locus_tag="TVB59_001662"
     CDS             2289..4445
                     /locus_tag="TVB59_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEL1010531.1"
                     /translation="MTLFYKRTFVSQIDARDCGVAALASIARYYGSDYSLAHLRELAK
                     TNKEGTTALGIVMAAKEMGFETRPIQADMTLFDMADVPYPLIVHVNKEGKLQHYYVVY
                     KSKKDYLIIGDPDPMVKVTKMSKERFASEWTGVTICLAPKPNYKPHKDQKNGLLGFFP
                     LIFKQRTLIFYIVLASVLVTVINIAGSYYLQGILDEYIPNQLKSTLGIVSIGLIITYI
                     LQQLMSFSRDYLLTVLSQRLTIDVILSYIRHIFELPMSFFATRRTGEVTSRFTDANSI
                     IDALASTILSLFLDLSILAIVGSVLLVQNSRLFLLSLISIPVYTIIICAFIKPFEQMN
                     HDVMQSNAMLSSAIIEDINGIETIKSLTSEENRYQKIDSDFVDYLDKSFKLSKYTILQ
                     ATLKQGAQLILNIIILWFGAQLVINGKISIGQLITFNTLLAYFTTPLENIINLQTKLQ
                     AAKVANNRLNEVYLVESEFKASQALYDLSLLQGDIQFEAVSYRYGFGKDTLSDITLTI
                     KQGAKVTLVGVSGSGKTTLAKMLVNFFEPYKGRITINQNDLKTIDKKNLRQYINYLPQ
                     QAYVFNGSILENLTLGAKQGISQEDILNACEIADIRHDIEQMPMGYQTELSDGAGLSG
                     GQKQRIALARALLTQAPILVLDEATSGLDILTEKKIIDRLMNMTDKTIIFVAHRLSIA
                     ERTDQIVVLNQGQIIETGSHQELMKQGGFYYHLFSE"
     gene            4456..5814
                     /locus_tag="TVB59_001663"
     CDS             4456..5814
                     /locus_tag="TVB59_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEL1010532.1"
                     /translation="MNPNMFKSAEFYQRRYHHLTTFLTIPLALLLTFLILFSCFVYKE
                     ITVTSYGEITPTQVIATVQSISNNPIIANHLTNNQPIKQGDSIIQYAKDLEESQKQVL
                     EKQLATYEKQKSSLNTLLLSLKQGQNLFQNDDQFGYVNTFNHFMSQAQDIDLGFSKIK
                     AETSQQAQLIQDSIVAINQQINSLSQQISDYEELRSAIINQSDSLSSNNPHQATLDAY
                     LSQSQANQETATNQLLFQIDQNLLNLKTSIDSLYRQRANLHQSTSYDNSLNTKLEILR
                     TQFLITASQQLTDVNHHITELKAQLEQATLQVNNLVIKASKSGIVQLNSAFEGKISIP
                     IGHDIAYIYPSLKQTKQALLTYYVSSESVSLLKKNQVVRLALDRHGNQPIVITGTIKT
                     IDELATKTKQGNLFKVTAKLTLSEKESTTIQYGQQGRVISVIAKKTFFDFYKDKLFKV
                     TE"
     gene            5914..6045
                     /locus_tag="TVB59_001664"
     CDS             5914..6045
                     /locus_tag="TVB59_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComC/BlpC family leader-containing
                     pheromone/bacteriocin"
                     /protein_id="HEL1010533.1"
                     /translation="MDKPTRQPKFQELTPSQLTQITGGGWLEGLQKVFNVSKPKLLK"
     gene            complement(6167..7501)
                     /locus_tag="TVB59_001665"
     CDS             complement(6167..7501)
                     /locus_tag="TVB59_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEL1010534.1"
                     /translation="MKLILFFLEMTTSIGLSLVLFSKISGRQLTWLEVAFSTFLRIGF
                     AVFFTIANHVADISLLNYWSLPIYMVVISWLLLRPLSKTLLIFYGLFPITLWSLWYRL
                     LGFFILPLFKLDYHLTNDGFWGIFTDIVSTLMVFLFLRWLRYDFRALRINLLSDRDKR
                     ILGVTNWSMVSYYFLIQLLAYLEYELAVDTYAYRQCMMLGYWIIFMGTVSRLDRSLRD
                     TLQERLTFQRELQLANIESYSRQIEELYREVRGFRHDYSNLIATLKFGIDNDSMSIVR
                     SVYQSVFKDSNKRFRKQKYDVGRLIHVTDTALKSLLAAKFSQALESGISVSLEVPEDI
                     SPQGMELIDFLTIVSILCDNAIEAAVEASSSKITISYFTLDNKQLFMIENTTKEEKID
                     LSFLYDFGVSTKGDNRGVGLYNAMEIINRYPNVMIKTISQNHVFGQTLELRL"
     gene            complement(7501..8250)
                     /locus_tag="TVB59_001666"
     CDS             complement(7501..8250)
                     /locus_tag="TVB59_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1010535.1"
                     /translation="MRVVILEDDMIQQRYLEKLIKELEVKHQLLFQGLDCFGRPHQLL
                     SAIKKNCGQQLFFLDIEIKNENKKGLEVARQIRQINPDAMIVFVTTHSEFMPLAFQYQ
                     VSALDYIDKELPQTEFVQRVETALLYAVRQNSETIAESAFYFTSRYAQVQVPFNDILY
                     IETSSRAHRVNLYTKKERMQFTGTLTDILKQESRFLQCHRSFLINHRNVVRVDKIERV
                     VYFRNGSSCLIARSKMNSVLTTIENLHRGDN"
     gene            complement(8877..9080)
                     /locus_tag="TVB59_001667"
     CDS             complement(8877..9080)
                     /locus_tag="TVB59_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class IIb bacteriocin, lactobin A/cerein 7B
                     family"
                     /protein_id="HEL1010536.1"
                     /translation="MKQYEDFQMLYELDLASVNGGKINWGSVAGHCAGGAIVTGAFSG
                     PLYVLGAGIGCIVGAGQAIINGL"
     gene            complement(9097..9354)
                     /locus_tag="TVB59_001668"
     CDS             complement(9097..9354)
                     /locus_tag="TVB59_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEL1010537.1"
                     /translation="MNTETINQFDVMNIEALATVEGGYSGKDCLKDMGGYMLIGAGSG
                     ALWGAPAGGIGVLPGAFVGAHVGAIGGGFACMGGMIGNRFN"
     gene            complement(9675..11042)
                     /gene="rlmD"
                     /locus_tag="TVB59_001669"
     CDS             complement(9675..11042)
                     /gene="rlmD"
                     /locus_tag="TVB59_001669"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEL1010538.1"
                     /translation="MNVKIKQKIPLKIKRMGINGEGIGFYKKTLVFVPGALKGEEVFC
                     QVTAVKRNFAEARLLVINKASKNRVKPACSIYETCGGCQIMHLAYPKQLYFKDDIIRQ
                     ALKKFKPKGYEEFEIRHTLGMAEPQHYRAKLQFQTRSFGGSVKAGLFSEGSHCLVAID
                     DCLVQDQLTQAIVNHVTQLLDRYRIPIYNERRVAGIRTVMVRRAQASDQVQLIFVSSK
                     EVRLAGLIAELTAAFPQIRTVALNINTSKTSDIYGAKTEILWGQETIQEEVLSHSFAL
                     SPRAFYQLNPTQTEVLYSQVVQALEPTAEEHIIDAYCGVGSIGLAVANKVRSVRGMDI
                     IPEAIADARKNAQALGFDNAYYETGKAEELIPSWYAEGYRADALIVDPPRTGLDDKLL
                     QTILHYQPAKMVYVSCNTSTLARDLVPLVQVYDVIYIQSVDMFPHTARTEAVVKLQKR
                     QKPQQ"
     gene            complement(11039..12007)
                     /locus_tag="TVB59_001670"
     CDS             complement(11039..12007)
                     /locus_tag="TVB59_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1010539.1"
                     /translation="MTEKDKKDRDKVVSLQHYRQADAEDDMLFGHETEFFSDDLEALL
                     NSMDNQLLSDLEHFAGDRAYDLIKYLAFDEDCQHQAWLASKPMGWVNLEERPYLSQKF
                     ELAMLYKQNGLYEKALHHLLEIHQYDEGDHLGTRYEILALYVLKSDFTMAEAFYDSKD
                     YHRGDLLMEVPLMVGALLAEREELADDILANLAETVPDFVAIVRQKAFPIDDILAAGA
                     LESYEPNSLSSIYLAFFNILPLLMTAQYYLQHYVQEFFEGAEGELTFLEELDLPLSKV
                     NLFNQYGIHTLEDFSAWTTQELLDIPGVGKQMIARLKRLGVIFSQE"
     gene            complement(12147..>12312)
                     /locus_tag="TVB59_001671"
     CDS             complement(12147..>12312)
                     /locus_tag="TVB59_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEL1010540.1"
                     /translation="FKQAVDCDYITGDTVMIVRKNGRIFDYVLPNEEIRDWEVVIEER
                     VEEVMRELDK"
BASE COUNT         4012 a         2789 c         1894 g         3617 t
ORIGIN      
        1 atatgacagg ctacaggagt atcattcttt aaatgttaac aattgctaaa atttcgatat
       61 taggtctatc aatatcataa tataaaggat aaaaagaaac attaagttgt catgagctaa
      121 aaataacaaa aaaaagctat ttatcgttga tatatcaaca atgtcattat ttttatctaa
      181 acctctcaca gatctataga taaaataaat ttgaaaggtg aaaataacta tagtaaatat
      241 atatttcaga ttcatatcat attatgatga agccttatag gctaaataac cacaaacagc
      301 tgcacttcca actcctccga taacagctcc ccaaggtcca atcctacttc ccaactttat
      361 acctccaaca gcacaggtca aaccacctac tactgctgca ccggcagggt tccctccaca
      421 aatgtcgtta agttcttctt ctttgatttg ataataatga gtcataaaaa acctctcttg
      481 attaaaatcc acctgttgct cctgttactc ctgcccacaa tgatacgcca aatttggctc
      541 caatgtaacc acatgctccc ataaatggag caccggcacc acttgcagca caaatagctg
      601 tccctaaccc ccagccacta acagcagcgg taccaccttc ccaaacatta gcttgccaat
      661 tattctttcc accttcaatg tgagcaagct tgtcagcgtc tataatatta aattgtttca
      721 ttaatgtcgt attcatcgtg aatacctcct atatttattt tttgtctgct gcaactgaca
      781 aacccagtat agcagataaa caatcgcttt cagtatttaa gtcttaaaat gtcgtcgaaa
      841 cgtcttgaat ggtaatacga aaaccgttaa caccaattca gtgaaaattc ctaataccca
      901 taacaaatat gagaaagctg tcttaattgc ttcaaaagct gagtttcctc ctttgacggc
      961 tgaaggctct atgctgtaat gacaaatagc ccaatcttaa atgactattt tatttttcca
     1021 gatagcaata catcatcaac agctgatgaa aataatacat ttgtggcctc agcttactaa
     1081 cttaagcctc tagaaataag gaaaagcaac tgatttgata gctaatagcg cagataatat
     1141 ttcttttcca agctcaataa gactcaaaaa taagttcttt gtaagaaaaa ataaatcact
     1201 aaccaaatga gataagctta ttgcccttgc aattatctca agctacttct tgtccgaaac
     1261 caccctagat agttaactac cacaaaacaa taggtatcag ctttaaactg atacccattg
     1321 ttatatcctg cgattagcca atcaactcaa tcgttactta ctttaccttc agctagccat
     1381 ctcacaaaat agcattgaca accttttcat gtcatttggc ctattgtgac tcaacaaaac
     1441 aataacgcca atacaacgat aaggtatgag cgttttatta tcgcctaata actcccaatg
     1501 atattaggcc tctacctagc tgtttatcac attctttgta agtagagatt tctttataga
     1561 atttagccat ttctacactc attgtttcaa ctcttatctg cttaacagct aattgacgca
     1621 gagattcaga tagcatcatc acttctctgt caaagttact tgactcccct actctatctt
     1681 taaatcttac cagaatgact cgctcttctg atgttaaggt tggatctaaa attaaattat
     1741 aaaccttatt tagtatctct tcttgcgtca acatacccaa ctaccctcta taccctggat
     1801 ggaaataacc acctcctaaa gaggatatcc aaccattaac aataacatct ttagttgctt
     1861 caaaattact tttagtaaca atatagcccc attcgccatt gctatatcgg caggcatacc
     1921 cattagaacc agacattaca aacttacaaa ttcctttgcc gccaccctca atgtgagcaa
     1981 gcttgtcagc gtctataata ttaaattgtt tcattaatgt catattcatc gtgaatatct
     2041 cctatattta ttttttacct gttgcaagca acaaacccag tatagcagat aaataactgc
     2101 tttcagtatt taagtcttaa aatgtcgtcg aaacgtcttg aatggtaatg tcgcaactga
     2161 ttaaaaaaga gtgttaatat cattattccc atttaagacg tttcaacgac tattcaagac
     2221 tagctcagtt tttttctgag cttttgtggc acaatagagt cgttacaaca gagaaaggaa
     2281 gccaaccaat gacactcttt tataaaagaa cctttgtatc acaaatagat gccagagatt
     2341 gtggcgtagc tgctctagcc tcaatcgcaa ggtattatgg ttcagattat tcattagctc
     2401 atttgagaga attagcaaaa accaataagg aagggacaac agccctcggt attgtcatgg
     2461 ctgctaagga aatgggattt gaaaccagac ccattcaagc ggatatgacc ctctttgaca
     2521 tggcagacgt gccctatcca ttgatcgtcc atgtcaataa agaaggaaag ctacagcact
     2581 actatgtggt ctacaaatct aaaaaagact atcttatcat tggtgatccc gatccaatgg
     2641 tcaaggtcac aaaaatgtcc aaggaacgct ttgcttcaga atggacaggt gtcaccatat
     2701 gtcttgctcc taagccaaat tataaaccac ataaagacca aaaaaatgga ctattaggct
     2761 tctttccgct tatttttaaa cagcgaaccc ttatatttta tatcgtgtta gcttctgtct
     2821 tggtaacggt cattaatatt gctggttcat actatctcca ggggatttta gacgagtata
     2881 ttccaaatca gctgaaatct accttaggga ttgtatcaat tggtctcatc attacctata
     2941 tactccagca gctaatgagc ttttctagag attatctttt aactgtcctt agccaacgtc
     3001 ttacgattga tgtgattctg tcctatatcc gccatatttt cgaattgccg atgtcctttt
     3061 ttgcaacacg tcgaacaggt gaggtaacct cgcgctttac agatgctaac tctattattg
     3121 atgcactcgc ttcaaccatt ttatccctct ttctagacct ctctatatta gctattgtcg
     3181 gaagtgttct tttggtgcaa aatagcaggc tttttctgct atctctgatt tctatcccag
     3241 tatataccat tatcatatgt gcctttataa agccgtttga acaaatgaat catgatgtga
     3301 tgcaaagcaa tgccatgcta agctctgcta ttatcgaaga tatcaacggg atcgaaacca
     3361 taaaatcact aaccagtgaa gaaaaccgtt accaaaaaat tgacagcgac tttgtggatt
     3421 accttgataa gtcttttaag cttagtaaat ataccatctt acaagccaca cttaagcaag
     3481 gagcgcagct aattctgaat atcatcattc tttggtttgg ggctcaactg gtcattaatg
     3541 gtaaaatttc aatcgggcaa ttaattacct ttaacacact tcttgcctat tttacaaccc
     3601 ctttagaaaa tatcattaat cttcaaacca agctccaagc agctaaggtt gccaataatc
     3661 gtctcaatga ggtctatctt gtagagtccg aatttaaagc ctcgcaagcc ttatacgatt
     3721 tatcgctctt acagggtgac attcagtttg aagctgtttc ctacaggtat ggctttggca
     3781 aggatacatt atcagatatt acattaacca ttaagcaggg agcaaaagta acccttgttg
     3841 gtgtcagcgg ctcaggaaaa acaaccctag ccaagatgct cgtcaatttc tttgaacctt
     3901 ataaaggacg tataaccatc aaccaaaacg atctcaagac cattgataaa aagaatcttc
     3961 gacaatacat caactacctt ccacaacaag cctatgtgtt taatggatct atcttagaaa
     4021 atctaacctt gggagccaag caaggcatca gccaggaaga cattcttaac gcctgtgaga
     4081 ttgctgacat tcgtcacgac atcgagcaaa tgccaatggg ataccaaacc gagctctctg
     4141 atggggctgg cttatctggc ggacaaaaac agagaattgc acttgctaga gcattactaa
     4201 cccaagctcc tatactagtt cttgatgaag caaccagcgg acttgacata ctgacagaaa
     4261 agaaaatcat tgaccgtctc atgaacatga cagacaaaac gattattttc gttgcccacc
     4321 ggcttagtat cgcagagcgc actgatcaga ttgttgttct taatcaaggg caaatcattg
     4381 aaacaggcag ccaccaggaa ttaatgaaac aaggtggatt ttattaccac ctatttagtg
     4441 aataaggaga caatcatgaa tcccaatatg tttaaaagtg cggaattcta ccaaagacgc
     4501 tatcatcatt tgacaacatt cttaacaatt cccttagccc tcttgttgac ttttcttatc
     4561 cttttttctt gctttgttta taaagaaata acggtaacgt cctacggaga aatcactccc
     4621 actcaagtca ttgcaacagt ccaatctatt agcaataatc ctataattgc gaaccatctc
     4681 accaataacc agccaatcaa acaaggagac tctattattc aatatgctaa agacctagaa
     4741 gagtctcaaa agcaggtact tgagaaacaa ttagctacct acgaaaagca aaaaagcagc
     4801 cttaatactc tattgttaag cttaaaacaa ggccagaacc tttttcagaa cgatgatcaa
     4861 tttggttacg tcaatacctt taatcatttc atgagccaag cccaagatat tgaccttggt
     4921 ttctcaaaaa taaaggcaga gaccagccag caggcccagc tgattcagga ctctattgtt
     4981 gctatcaatc agcaaataaa tagtctttct caacaaatat cagactatga agagcttcga
     5041 tctgcgatca ttaaccaatc cgatagtcta tcctccaata acccacatca agccaccctt
     5101 gatgcctatc tctctcaatc tcaagcaaac caagagactg ccaccaatca gcttctattt
     5161 caaatagacc aaaatctttt aaacctaaaa acctctatag atagcctcta taggcaacgt
     5221 gctaatctac atcaatctac cagctatgat aatagcctca acacaaagct agaaatactc
     5281 cgaacacagt ttttgataac agcctctcag cagttaacag atgtcaatca tcatattact
     5341 gagctcaagg cgcaattgga gcaagccact cttcaggtaa acaatctggt gatcaaagcc
     5401 tcaaaaagtg gcattgttca gctcaatagt gcttttgaag gcaaaattag tatcccaatc
     5461 ggtcacgata ttgcctacat ttatcctagc ctcaaacaaa caaaacaagc cttgctcact
     5521 tactatgtca gctctgaatc tgtttctctc cttaagaaga accaggttgt caggctagct
     5581 ctagatagac atggaaatca accgatagtc attacgggaa ccattaaaac cattgatgag
     5641 ctagcgacca aaaccaagca gggaaatctt tttaaggtta cagccaaact aacactttct
     5701 gaaaaagaaa gcactactat tcaatatggt cagcagggac gagtgataag tgttattgcc
     5761 aaaaaaacat tctttgactt ttataaggac aagctcttta aagtgacaga ataaccattt
     5821 agcgcttttc aacgaccatt taggacatag agtacaacaa agagtcaaga taagctataa
     5881 taacatagac agtatttaaa aggagctttc aatatggata aaccaactag acaaccaaag
     5941 tttcaggaac taacgccttc tcagttaact cagattactg gaggaggctg gcttgaaggt
     6001 cttcaaaaag ttttcaatgt ctctaagcca aaactactaa aatagtaaca ttctccattt
     6061 tcaaaacacc actacctaaa ggtactgaga cactatcgga atgatgtgat cctaaacatc
     6121 aaatctgata ggtgcaagac agttttcctt tactagtggt gtttttttat aacctaagct
     6181 caagtgtttg accaaataca tgattttgac ttatagtctt aatcatcaca ttgggataac
     6241 gattgataat ttccatagca ttataaagtc ccacacctct attatccccc ttggtgctta
     6301 ctccgaaatc atatagaaag gatagatcaa tcttctcttc cttagttgta ttttcaatca
     6361 taaatagttg cttattgtcc aaagtaaaat aagaaatcgt tatcttagac gaagaagctt
     6421 caacagcagc ctctatagca ttatcacata aaatagacac aatagtaaga aaatcaatca
     6481 gctccatgcc ttgcggactg atatcctctg gaacctctaa agatactgaa atcccacttt
     6541 ctaaagcctg actaaatttt gcagctaaaa gacttttcaa ggctgtgtca gtgacatgga
     6601 taagacgccc aacatcatat ttttgcttgc gaaatcgttt atttgaatcc ttaaagaccg
     6661 attgataaac tgacctaaca atagacatgc tatcattatc tataccaaac tttaacgtgg
     6721 caatcagatt gctatagtca tgacgaaatc ctcgaacctc tctgtaaagc tcctctatct
     6781 gacgactata gctctcaata tttgccagct gcagctctct ttgaaaggtc agtctttctt
     6841 gcagtgtatc tcttagcgac cggtccagtc tcgacacagt tcccataaat ataatccaat
     6901 agccaagcat catgcattga cgataggcat aagtatcaac agctagctca tactctaaat
     6961 aagcaagcaa ttggatcaaa aaataatagc taaccataga ccagttggtc acacctaaaa
     7021 ttcttttatc cctatcagat aaaagattaa ttcttaatgc tctgaaatca tatcgtagcc
     7081 accgcaaaaa gagaaaaacc atcaaagtag atactatatc tgtaaaaatt ccccaaaatc
     7141 catcatttgt taaatgataa tcaagtttaa aaagaggtaa gataaaaaaa ccaagcagtc
     7201 ggtaccaaag gctccacagg gtaataggaa atagcccata aaatatcaat aatgtttttg
     7261 ataagggtcg cagcaatagc catgatatca ctaccatata aattggaaga ctccaataat
     7321 tgagaagtga aatgtcggca acatgattag ctatagtgaa aaaaacagca aatcctattc
     7381 ttaaaaaagt actgaaagca acttcaagcc aggttaattg acgtccactg attttggaaa
     7441 agagcactaa cgataagcct atacttgtcg tcatttctaa gaaaaataaa ataagcttca
     7501 ttaattatct cctctatgta ggttctcaat tgttgttaaa acactgttca ttttactacg
     7561 agcaattaag cagctagagc catttcgaaa ataaaccact cgctcaatct tatctaccct
     7621 aacgacattc ctatgattaa tcaaaaaaga acgatgacat tgcaaaaaac gagactcttg
     7681 cttcaaaata tccgtcaaag tccccgtaaa ttgcattctc tccttttttg tatacaaatt
     7741 gacacgatgc gctcgtgacg atgtctcaat atacaggata tcattaaaag gcacctgtac
     7801 ctgagcataa cgagatgtaa aataaaaagc actttccgct atcgtttcac tattttgccg
     7861 cacagcatat aataaagcag tctctacccg ttgaacaaac tcagtttgag gcagctcttt
     7921 atcgatatag tccaaagcag atacctgata ctgaaaagcc aagggcataa attccgagtg
     7981 agtcgttaca aaaacaatca tcgcatctgg atttatctga cgaatttgcc tagcaacctc
     8041 aagccctttt ttgttctcat tttttatctc aatatctaaa aagaatagct gctgaccaca
     8101 gttcttcttg atagcactta atagctgatg aggccttcca aaacagtcaa gtccttgaaa
     8161 taatagctgg tgcttaacct caagctcttt aatgagcttt tctaaatatc tctgctgaat
     8221 catatcatct tctaaaataa ctactctcac ctaaactcag tcccctatcc aatctgcaga
     8281 agcattagca ctactaccgt ttcaacaaaa taataagcac aataacaaaa ataaatccat
     8341 taaaaacaac tgcatcaaaa ctcataaaaa taatattttg tacttatttt agcataaaat
     8401 accatttttg aatacactaa tctctaataa actaatgcta tctagtctta gctagcaata
     8461 acctagtgct tctaacaaca ataatcagct caacaatttt tagcagctac ctttttaaaa
     8521 aaactgggat aaaaagattt ctcaggtaag aaaaatagag attcaccaaa cagtgaatct
     8581 ctattttttg aactgaaact ccttttgtcc caaactcata agatgtattg actttatgag
     8641 atgaacaatt tgttacactt gatttgatca tcggggttta gaaaaaatag tgaaaagaat
     8701 cctcataatt cgtgaaaaat ataatttctc acccaaaaat ccaattcaag attgtattta
     8761 taagaagtag catgattaaa gttatagaaa ttcttatcaa cgcttcttct tttttaacaa
     8821 caccaaatat caatagtata atcggaacta aaactaatac tactaataat attgttttat
     8881 aatccattga taatggcctg tcctgcacca acaatgcatc ctattcctgc acccaataca
     8941 tacaatggac cagagaaagc acctgtaacg attgctccac ctgcacaatg ccctgcaaca
     9001 gagccccaat taattttacc gccatttaca cttgccaaat caagctcata taacatctga
     9061 aaatcttcgt actgcttcat ggtatatact cctttcttag ttaaatctat tacctatcat
     9121 tccacccatg catgcaaaac ctcccccaat tgcaccaaca tgtgcaccaa caaatgcacc
     9181 tggaagtacg ccaatccctc ctgctggggc accccacaaa gccccacttc cagctcctat
     9241 taacatatat cctcccatgt ctttaagaca gtccttacca gaatatccac cttcaacagt
     9301 tgcaagagcc tctatattca taacatcaaa ttgattaatc gtttctgtat tcattttgaa
     9361 tacctccata acatattttt tctttatgtc gcgatcacga tttaagtata gcattctagt
     9421 atcatatttt ttctaaaagt cttaaacggt cgttttttca tcgtaaacgg tcattttcaa
     9481 tcgttttcaa ccgttcaaga caaaattaac taccattcag gattttcatt ggataaatag
     9541 ctattttttg gctctttgcc aacccactaa agctattaat aaaaaaataa gacagtagtc
     9601 acatttaggc tactgtctct tttatctaaa gccttgatcg gtaagaaaag agccagtctt
     9661 ttccaactaa tcgattattg ttgtggtttt tgtcgctttt gtagcttcac tacagcctcg
     9721 gtccttgctg tgtgtggaaa catgtcaaca gattgaatat atatcacatc atagacctga
     9781 accaagggta ccagatcacg agccaaggtt gaggtattac aggagacata aaccatttta
     9841 gctggctgat agtgtaaaat cgtttgtaat agcttgtcat ctagtcctgt tcgaggtgga
     9901 tctacaatca aggcatcagc tcggtagcct tcagcgtacc agcttgggat cagttcctct
     9961 gccttgccag tctcataata agcattgtca aagcccaatg cctgcgcatt tttcctagca
    10021 tcagcaattg cctctggaat aatatccata ccacgaacag atcttacttt gtttgcaact
    10081 gccagaccaa ttgagccaac accgcaataa gcatcaataa tatgctcctc agctgtgggc
    10141 tcaagcgcct gaaccacttg actatataaa acctctgtct gtgtgggatt aagctgataa
    10201 aaggctcttg gcgacagggc aaagctatgg ctcaaaacct cctcttgaat ggtctcctga
    10261 ccccagagaa tctcagtttt ggcgccataa atatcactcg tttttgaagt attgatgttt
    10321 aaagcaacag tcctgatttg tggaaatgca gcagtcagct cagcaataag acctgccagc
    10381 ctcacctctt tactgcttac aaaaatcaac tgaacctgat cactggcctg tgccctacga
    10441 accataactg tacgaattcc agctactctg cgttcattat agataggaat cctataccga
    10501 tcaagcagct gagtcacatg attaacaatc gcctgtgtta gctgatcctg aaccagacaa
    10561 tcatcaatgg caaccaagca atggctccct tctgaaaata agcctgcctt gacggagcca
    10621 ccaaacgaac gcgtctgaaa ctgtaatttt gctcggtaat gctgcggctc tgccattcct
    10681 aaggtatgac gaatctcaaa ctcttcatac cccttaggct taaacttttt taaggcctgc
    10741 cgaatgatgt catccttaaa gtagagctgc ttaggatagg ccagatgcat gatttgacag
    10801 cctccacagg tctcataaat ggaacaggcc ggcttcaccc ggtttttaga agccttatta
    10861 atcaccaaga gccttgcctc agcaaaattg cgcttaacag cagtcacttg acaaaaaacc
    10921 tcttctccct tcaaggctcc gggaacaaag accaaggtct ttttataaaa accaattccc
    10981 tcaccattaa tccccattcg cttaatctta agcggtattt tttgctttat tttgacattc
    11041 attcctgact aaatattact cctaatcgct taagccttgc tatcatctgc ttgccaacac
    11101 ctggaatatc aagaagctct tgagttgtcc aggccgaaaa atcctccaga gtatgaatcc
    11161 catactgatt aaacaaattg accttactta aaggaagatc aagctcctct agaaatgtta
    11221 gctcgccttc agccccttca aaaaattcct gaacataatg ctgcaggtaa tattgtgcag
    11281 tcatcaatag cggtaggata ttaaaaaagg caaggtaaat acttgataag ctgtttggct
    11341 cgtagctctc cagggcacca gcagctaaaa tatcatctat cggaaaggct ttctgtctga
    11401 caattgccac aaagtctggc accgtctcag caaggttagc caaaatatca tcagctagct
    11461 cttctctttc agctaatagc gctccaacca tcaaaggaac ctccatcaac agatctcctc
    11521 tatgataatc cttactgtca taaaaagcct ctgccatcgt aaaatcagac tttaacacat
    11581 aaagagctaa gatttcatac cttgtcccta agtgatcccc ttcatcgtat tgatgaattt
    11641 ctaagaggtg atgtaaagct ttttcataaa gaccattttg cttatacagc atcgccagct
    11701 caaatttttg agacaagtaa ggtctctctt caagattcac ccatcccata ggcttagaag
    11761 caagccaggc ctgatgctga cagtcttcat caaaggccaa atacttgatt aagtcatagg
    11821 ctctatctcc tgcaaagtgc tccaagtccg acaacaactg gttatccatg ctgtttaaaa
    11881 gagcctctaa gtcatcactg aaaaactctg tctcatgtcc aaagagcata tcatcttctg
    11941 catcagcttg gcgatagtgc tgtaagctaa caaccttatc tctatctttt ttatcttttt
    12001 ctgtcataat gccctttcaa tctattgacc atttatactc ttattttacc atttttgtta
    12061 taatgagggt atagataaaa ctcctaaaat tgtggcttta caatgtcgtt ccccgacaat
    12121 tccccgactt ctggacgagg tcttttttat ttgtctaatt ctctcatcac ctcttccact
    12181 ctttcctcta tcacaacctc ccaatctctt atctcctcat tcggcaacac ataatcaaaa
    12241 atccgtccgt ttttgcgcac aatcataact gtgtctcctg tgatatagtc acagtctact
    12301 gcttgcttaa ac
//
LOCUS       DARYNN010000056        12157 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.056, whole genome shotgun sequence.
ACCESSION   DARYNN010000056 DARYNN010000000
VERSION     DARYNN010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12157
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.056"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(152..433)
                     /locus_tag="TVB59_001672"
     CDS             complement(152..433)
                     /locus_tag="TVB59_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEL1010541.1"
                     /translation="MTTQKAYMYVLECADKTLYTGYTTDLDKRLKAHNAGKGAKYTRC
                     RLPVSLLYYESFDSKQAAMRAEALFKKRNTRQQKLTYIAEQQNKKAKPD"
     gene            complement(466..1233)
                     /locus_tag="TVB59_001673"
     CDS             complement(466..1233)
                     /locus_tag="TVB59_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEL1010542.1"
                     /translation="MLHSILKDGERIDQLFSSDVQIIQNKEVFSYSIDSVLLSRFPKL
                     PSRGLIVDLCSGNGAVGLFDSTQTKASIVEIELQPRLADMGQRSIRLNQLEDQVTMIC
                     DDLTNLLQHVPRSGVDIILYNPPYFKSSQTSKKNLSEHYLLARHEITTNLAKICQIAR
                     HALKSNGRLAMVHRPDRFLEILDTLKINGLAPKRLQFVYPKLGKEANMLLIEAIKDGS
                     MEGLKILPPLIVHKDNGDYTDTIKEIYFGAKDKAFKN"
     gene            1352..2092
                     /locus_tag="TVB59_001674"
     CDS             1352..2092
                     /locus_tag="TVB59_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEL1010543.1"
                     /translation="MFYVYLRGLVVFLLWVVNGNAHYHNEDRILDKSENYILVAPHRT
                     FWDPVYMAFAARPKQFIFMAKKELFTNRLFAWWIKMCGAFPIDREKPSPDAIRYPVNM
                     LKKSNRSLVMFPSGSRHATDVKGGVAVIAKMAKVKIMPAAYQGPMTLKGLLAGERVDM
                     NFGHAIDVSDIKRMNDEEIEEVARRIQAEFDRLDQEMAPFKSNQRRSMLTYLYRIPLG
                     ILLVLILALTMLFSYLASFVWDPDKHRS"
     gene            2411..3091
                     /locus_tag="TVB59_001675"
                     /pseudo
     CDS             2411..3091
                     /locus_tag="TVB59_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184716.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
     gene            3072..5315
                     /locus_tag="TVB59_001676"
     CDS             3072..5315
                     /locus_tag="TVB59_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEL1010544.1"
                     /translation="MRFPLTKYFPIAPIQFALLVLVLHYLIYRPSWLTAGLLAGLLVL
                     LGYRFVLKQVLKTLLLLGLFGCLFAYQKGQLEANQINQPDRLSTVELIPDSIMVNGDH
                     LSFIGRHSGHHYQLAYRMTSKEEADFFKQQSQFLKLKADIRLEEAAGLRNFKGFNHQA
                     YLAYQGIFRVGKIKSLQSLKTISPRSVSDRISQWRRQAIVWCQSRFPQPMSHYMTGLL
                     FGYLDKSFGQMTELYSQLGIIHLFALSGMQVGFFLTYLRRGLVWLHIPIDKIKLLEVV
                     CSFCYSGLTGHSISVIRSLLQAQLRHIGLTGLDNLAMTFLMMFLINGHFLMSIGGVLS
                     FAYAFIIATVRFEELSGNKQRLLKALAISFGIVPLLAYYFSVFNPISVVLTALLAYLF
                     DGLILPGLAILFFFSPLAVVTAVNPFFLYLEKGIGMIGSYFSAPLVLGSPTALQLCLC
                     MACLAIVYDYRGNRGLQLVAGGLLLLTLFTVKWPMTNEVTLVDVGQGDSIFIRDKQNH
                     TMLIDVGGVPAPQEKEQWRRKYQACNAHKTLIPYLRSRGVDTIDQLVLTHTDTDHVGD
                     MEAVVKAFRVKQIYVSQGSLTNASFVKRLQGLAAKVKAISAGDHLPIMGSFLEVLYPW
                     EIGDGKNNDSLVLYGRLLDKSFLFTGDLEAEGEERLIARYPKLKADVLKAAHHGSKGS
                     SIPAFLDHIQPQLSLISAGRNNQYQHPNPETLARFEARHIPYYSTASKGAIRLTGQAH
                     WQLESCR"
     gene            5428..6489
                     /locus_tag="TVB59_001677"
     CDS             5428..6489
                     /locus_tag="TVB59_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEL1010545.1"
                     /translation="MIAIEKIDALSKESLGLITVVTGEDIGQYSHMKALLLKKIAFDP
                     ADLTYSYFDMSEALYQTAEMDLVSMPFFADQKVVIFDHLLDITTSKKSYLKEKELKAF
                     EDYLENPVETTRLVIFAPGKLDGKRRLVKILKRDALIFEASPLKAAEKRTYFQKYSHQ
                     LDLSFASGAFDQLLLKSNDDFSQIMKNMTFLKAYKKSGPITVEDIAQAIPKSLQDNVF
                     DLTRLVLQGKIDAARELVHDLRLSGEDDIKLIAIMLGQFRLFLQLATLVRSGKTEQQL
                     VTSLSDLLGRRVNPYQVKYALKDSRALSLSYLQLAVKTLIETDYHIKTGVYTKDYLFD
                     LALLKLVAHSQGNTDLSDL"
     gene            6567..7172
                     /locus_tag="TVB59_001678"
     CDS             6567..7172
                     /locus_tag="TVB59_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEL1010546.1"
                     /translation="MTITLPDLPYAYDALEPYFDTETMTLHHDKHHATYVANTNTALE
                     KYPELGENLEELLADVSSIPADIRQAVINNGGGHLNHALFWELLSPEKQEVSADVAAA
                     IDDAFGSFAAFKEQFTAAATGRFGSGWAWLVVNKAGQLEITSTANQDTPISEGKQPIL
                     ALDVWEHAYYLNYRNVRPNYIKAFFEIINWKKVSEFYQAAK"
     gene            complement(7423..8637)
                     /locus_tag="TVB59_001679"
     CDS             complement(7423..8637)
                     /locus_tag="TVB59_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3114 domain-containing protein"
                     /protein_id="HEL1010547.1"
                     /translation="MKYIHSGLMFLLFVLFVVSFAKHEQARLAFEQSHQAYKDMVISF
                     EKRHIKQQPSSLSDQFQLRKDLLHYAKKLAQDGWSYEAIEKGYLGHLKPKQASYNFEQ
                     LYQSLQIIGSPAFHRMWERQPRAQHKLEAKRDLSLLLSYVKMPEELSGQSAETKQLLK
                     QFSPSLSPTDAFWDQLASLIQLYYDHLEHIPYQTFNRKLYQLRYVLSVQQIEWVRNNY
                     GRAGKTDADALARYLATLDESDYSLNESARYHNKVASHLDTANQLQITYPDNFPQANY
                     KILIHFHSEFILSEAGHFLAALDPQQPSQNGLINGSSFNYANQNNDLHRLLDIEPIEL
                     FEPDFIETAMINLDSPFIVPDLEQQNDQQHPIFSRDGKSSKQLTKAAAKAFKKLLRHY
                     QQAHQSFPSKTP"
     gene            complement(8647..9675)
                     /gene="queA"
                     /locus_tag="TVB59_001680"
     CDS             complement(8647..9675)
                     /gene="queA"
                     /locus_tag="TVB59_001680"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEL1010548.1"
                     /translation="MNTNDFDFELPEELIAQTPLEQRDRSKLLIIDHQEHTMTDSHFD
                     HIIDQLEPGDALVMNNTRVLPARLYGEKMETHGHVELLLLKNIQGDQWEVLAKPAKRL
                     KAGAQISFGDGRLKARVIQELEHGGRIVEFSYDGIFLEILETLGEMPLPPYIHEKLAD
                     AERYQTVYAKENGSAAAPTAGLHFTQELLQKIEAKGVHLVYLTLHVGLGTFRPVSVDN
                     IDEHDMHSEFYLLSEEAAQTLRKVKAAGGRIIAVGTTSIRTLETIGSKFQGQILADSG
                     WTNIFIKPGYQFKVVDAFSTNFHLPKSTLVMLVSAFAGRDFVLEAYKHAIDEHYRFFS
                     FGDAMFVK"
     gene            9943..10647
                     /gene="nagB"
                     /locus_tag="TVB59_001681"
     CDS             9943..10647
                     /gene="nagB"
                     /locus_tag="TVB59_001681"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEL1010549.1"
                     /translation="MKIIRVQDQLEGGKVAFSLLKESLAKGATTLGLATGSTPITFYQ
                     ELVNSDLDCSALTSINLDEYVGLPVENDQSYDYFMRDQLFNAKPFKESFLPNGLADDL
                     EAEVKRYDQVIAEHPIDFQILGIGRNGHIGFNEPGTSFAEKTHVVDLQASTIEANSRF
                     FASIDDVPKQAISMGIASIMASKMIVLLAFGKEKAAAIKGMVSGPVTEALPASVLQQH
                     GNVVVIIDEAAASELD"
     gene            10819..11535
                     /locus_tag="TVB59_001682"
     CDS             10819..11535
                     /locus_tag="TVB59_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEL1010550.1"
                     /translation="MRLDKLLEVTGFGSRNQVKQLIKGRSVLIDGQPARAGCQSVDSG
                     LQVIMVNGRQIKAFAHRYYLLHKPAGVVSACSDRKHQTVIDLIRKEDRVANLYPIGRL
                     DRDTTGLVLLTDNGPLGFRMLHPKHHVNKTYLVTVNGSLAADAVPFFENGVTFLDGTR
                     CKSAALRIIKADQMESQAEVTLSEGKYHQIKKMFLSYGLKVTQLKRIGFAEIALGDLA
                     EGAYRQLTVKEKKLIKTYLT"
     gene            11627..>12157
                     /locus_tag="TVB59_001683"
     CDS             11627..>12157
                     /locus_tag="TVB59_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEL1010551.1"
                     /translation="MLTALDQDQRVISLTDGSSPSRKQAFTCPACGAAVRLKKGRIIR
                     PHFAHISLSHCQYLTENESHEHLRLKADLYRSLSRSETAEVEAYLPDLNQIADLLVNK
                     HLALEIQCSQLPIKRLEQRSRAYQANGYQVRWLLGRKLWLQKRLTGLQRQCLYFSWQL
                     GFHLWELDVEHHLIRLK"
BASE COUNT         3303 a         2348 c         2832 g         3674 t
ORIGIN      
        1 aagtccttgg aggttttgtt ttgctgcttt tttggtcttg gtctttagta gccttgggca
       61 agcggagctt tgacctagtg tgggtctgtc tcaactgttg tcagctagtc ccatagtggt
      121 gcttggccgc ggcttaggag gcgtcaggag cttagtctgg cttcgctttt ttattttgct
      181 gctctgcaat ataggtgagc ttttgctgtc tggtgtttcg ttttttaaac aaggcttcgg
      241 ctctcatcgc agcctgcttg ctatcaaagc tttcataata cagcaggctg acaggtaagc
      301 gacagcgtgt gtattttgct cctttaccag cattatgggc tttgagacgc ttgtctaaat
      361 ctgttgtata gccagtatag agggttttgt ctgcacattc taaaacgtac atgtaagcct
      421 tttgagttgt catgatgaaa aaacctcttg atgcagaaga gcctgctagt tcttaaaagc
      481 cttgtccttg gctccgaaat aaatctcctt aattgtatcg gtatagtctc cgttgtcttt
      541 atggacaata agtggtggca ggattttcaa gccttccata gaaccatcct tgatggcctc
      601 aatcaagagc atgttagcct ccttaccaag ctttgggtag acaaattgca gccgctttgg
      661 agcaagaccg tttattttta aggtatcaag aatctctaaa aagcgatcag gtcgatggac
      721 catagctaga cgaccattgg acttgagcgc atggcgtgct atctgacaga tcttagccag
      781 atttgttgtg atttcgtgtc tggctaggag ataatgctca gataggtttt tctttgaggt
      841 ctgactgctt ttaaagtaag gaggattata aagaatgatg tcaacacctg agcgaggcac
      901 atgctgaagc aggttagtca aatcatcaca aatcatcgtc acctgatcct ccaactgatt
      961 gagcctgata gagcgctgtc ccatatcggc taagcgtggc tgaagctcaa tttcaacaat
     1021 agaggccttg gtttgtgtac tgtcaaataa gcccactgcc ccatttcctg aacacaaatc
     1081 tacaatgagc ccacgtgatg gaagctttgg aaagcgagaa agcaagacac tatcaataga
     1141 gtagctaaag acctctttgt tttgaataat ctgaacgtcg cttgagaaaa gctggtcaat
     1201 ccgttcacca tcttttaata tcgaatgtag catatcatta ttatagcaaa aataatccta
     1261 tcagagtagg gggtgctgat tgagctttcc ctttaatatt aaaatatttc atggtacaat
     1321 gagtaggatt ataagtgaaa aggagactga tgtgttttac gtctatttac gtggcttagt
     1381 tgtcttttta ttgtgggttg ttaatggtaa tgcccactac cataatgagg ataggattct
     1441 tgataagtct gaaaattata ttctagttgc tccgcatagg accttttggg atcctgttta
     1501 catggcattt gccgcacgtc caaagcagtt tattttcatg gccaaaaaag agctcttcac
     1561 caatcgttta tttgcctggt ggattaagat gtgtggagcc tttccgattg atcgcgaaaa
     1621 gcctagtcca gatgccatta gatatcctgt taatatgctg aaaaaaagca atcgctcttt
     1681 ggtgatgttc ccaagtggga gccgtcatgc gacagatgtc aaggggggcg ttgctgttat
     1741 tgccaagatg gccaaggtca aaatcatgcc agcagcctat cagggtccta tgaccttaaa
     1801 gggcttatta gcaggtgagc gtgttgatat gaactttggt catgcgattg atgtttccga
     1861 cattaagcgt atgaatgatg aggagattga ggaggtagct aggcgtattc aggctgaatt
     1921 tgaccgctta gaccaagaaa tggctccctt taagtctaat caaaggcgct ctatgctgac
     1981 ctatctttac cgtattccat taggaatact tctggtgctt attttggctt taaccatgct
     2041 attttcttat ttagcaagct ttgtttggga tccagacaag caccgctctt aggtcgtgtt
     2101 atggattagc gctgaaggcg cgcaaaaatc agggctttgt tgctactcta ctgagactgg
     2161 cttgcagtta cccttctgac atgttatgtc taggatacga atgctactgg ttactcaagg
     2221 ctacaagaaa gccagcactt tccacagtaa ggggattagg taagccaagg taggttatgc
     2281 ttgtagtgta gctgtatgtt acaatttgat gaggttgaag aggtagtcca ttttggactg
     2341 ctttttttaa tatgctagaa aataggacaa ttttaaaggc ttttatcgaa taatatattg
     2401 aggtgaaaac atgttagaag aattgttctt aaagagtaaa gagatgataa agtcccctta
     2461 ttttctgtca cgttgtgtta ctggtgtgct gtctgtaggg cttttgctgg tgctgtggat
     2521 tgccttgact ggcaaggaaa aagcaagaga ggagtcagct ccatttcctg accattctca
     2581 ggttcagcag tcagaaaagc cagctcagct agaagctagt gagcaagaaa tggcggcagc
     2641 tgaggatatc gtagtggata ttaagggagc tgttcataag gagggtgtct ataagcttgc
     2701 taagggaagt cgtatcacag atctgattga gctagcaggt ggcttgacag accaagctga
     2761 taaaaatgct attaatctag ctgaaaagct atctgatgaa aaggtcgttt atgttgctaa
     2821 gctgggtgag aatatatcag tcattaaagg atcttcagct gaggctcaat cagcgtctgc
     2881 tgatcatcag aagcctgaaa aggttcattt gaacagagct agtcttgctg atttgcaaag
     2941 cattccaggc attggtgcaa agagagcata ggatattatt gatgtacgag aaagcctggg
     3001 tggctttaaa tctctagaag atctgagaaa ggtatcaggt attggtgcta aaacactgga
     3061 gaagctaaag catgagattt cccttgacta agtattttcc aattgctccg atacaatttg
     3121 cccttttagt gcttgttttg cattatttga tttatcgacc tagctggtta acggctggtt
     3181 tgttagctgg cttgttggta ttattaggct atcgctttgt cctcaagcag gtcttaaaga
     3241 cgcttctttt gctagggctt tttggctgtc tttttgctta tcaaaagggt cagctagagg
     3301 ctaatcagat caatcagcct gatcgcttat caacggttga gctgattcca gattcgataa
     3361 tggtgaatgg tgatcaccta tcctttatcg gtcggcactc ggggcatcat tatcagttgg
     3421 cttatcgcat gacctcaaaa gaagaggcag atttttttaa gcagcagagc caatttctaa
     3481 agctaaaggc tgacatcagg ctagaggaag cagcagggct tagaaatttt aagggcttta
     3541 accatcaggc ctatttagct tatcagggaa tctttagagt aggaaaaatc aaaagcttgc
     3601 agtcattgaa gactatctct cctaggtctg ttagtgatcg tattagccaa tggcgacgtc
     3661 aggccatcgt ttggtgccaa tctaggtttc cacagccgat gagtcattat atgacaggat
     3721 tgttatttgg ctatcttgat aagtcctttg ggcaaatgac agagctatac agccagctcg
     3781 gtattatcca tctgtttgct ttatctggta tgcaggtcgg cttttttctg acctacctgc
     3841 gtcgtggctt ggtctggtta catattccaa tagacaagat taagctactg gaggtggtat
     3901 gttcattttg ctattctggt ttgactggtc atagtatttc tgtgatacgt agcttgctgc
     3961 aggcccagct gcgtcatatt ggtttgacag gactagataa tctagcaatg acttttttga
     4021 tgatgttttt gattaatggt cactttctga tgtctattgg tggtgtcttg tcctttgctt
     4081 atgcttttat cattgctacg gtcagatttg aagagctttc tggcaacaaa cagaggcttt
     4141 tgaaagcctt agccatttcc tttggcattg tgcccttgct ggcctactat ttctcggttt
     4201 ttaatccgat ctcggtagta ttgacagcct tattagccta tttgtttgat ggtcttattc
     4261 taccaggtct agcgatcttg tttttcttct cgccccttgc tgttgtgact gccgtcaatc
     4321 cattcttttt atatttagaa aaggggatcg gcatgattgg aagctatttt agtgctccct
     4381 tggtgttagg aagtcctaca gccttacagc tttgcctttg tatggcttgc ttggctatag
     4441 tgtatgatta tcgagggaat cgaggcttac agttggttgc aggtggtttg ttgttgctga
     4501 cgctatttac ggtaaaatgg cccatgacta atgaggtaac gcttgtagat gttgggcaag
     4561 gagacagtat ttttattagg gataagcaaa atcataccat gctgattgat gtcggaggag
     4621 tgcctgctcc tcaggaaaag gagcaatggc ggaggaaata ccaagcctgt aatgcccaca
     4681 aaacactcat tccctatctt agaagccgag gagtagatac gattgatcaa ttggtgctaa
     4741 cccacaccga tactgatcat gtgggggata tggaggctgt tgtgaaggcc tttagagtta
     4801 agcaaatata tgttagtcag gggagtttaa ccaatgctag ctttgtcaag cgattacaag
     4861 gattagctgc caaggttaag gccattagtg ctggtgatca cttgcccatt atgggaagct
     4921 ttttagaggt gctctatcct tgggagatag gagatggtaa aaacaatgat tctttagtcc
     4981 tttatggcag gctattggat aaaagctttt tatttacagg tgatttggag gcagaaggag
     5041 aagaaaggct gattgctcgt tatcctaagc ttaaggctga tgttttaaag gcagctcatc
     5101 atggttctaa gggctcttct ataccagcat ttttagacca tatccagcct cagctaagct
     5161 tgatttcagc aggaaggaac aaccagtatc agcaccctaa ccccgaaacc ttggcacgct
     5221 ttgaagcgag acacattcct tactacagca ccgcaagcaa gggcgctatt cgcttaacag
     5281 gtcaagctca ctggcaatta gaatcctgta gataggctca ttgaaccaga gatatatgca
     5341 agggcctagg tctgggaatg aagtagagaa tgaaaaagat cagctttagc aaggtcatat
     5401 ttagtaagaa aatgctataa taaaaccatg attgcgatag aaaaaataga tgccttaagc
     5461 aaagaaagct taggcttgat tacggtcgta actggtgagg atattgggca atatagccat
     5521 atgaaggcgc tgctactaaa aaaaatagcc tttgatccgg ctgacttgac ttattcttat
     5581 tttgatatgt ctgaggcttt gtatcaaaca gctgagatgg accttgtaag catgcccttt
     5641 tttgctgacc aaaaggtggt tatttttgat catctgctgg acattaccac tagtaaaaaa
     5701 agctacctaa aggaaaaaga gctaaaggca tttgaggact atttggaaaa tcctgtagag
     5761 accacacgtt tggttatctt tgcaccagga aagcttgatg gcaagcgtcg tttggtcaag
     5821 attctcaagc gtgatgccct tatttttgaa gccagtcctt taaaggctgc tgaaaaaagg
     5881 acctattttc aaaaatacag tcaccagctg gacttgagct ttgctagtgg tgcttttgat
     5941 caattgctgt tgaagtcaaa tgatgatttt agtcaaatca tgaagaatat gaccttcttg
     6001 aaggcctata aaaaaagtgg tcctatcaca gtagaggaca ttgctcaagc gattcccaag
     6061 agcttgcagg ataatgtctt tgacttgaca agattggtgt tacaaggaaa gattgatgct
     6121 gctcgggagc tggttcatga tttgcgccta tctggcgagg acgatattaa gcttattgcc
     6181 attatgctgg ggcagtttcg tctgtttttg cagctggcaa ccttggtgcg gtctggaaaa
     6241 acagaacagc agctagtcac tagcctatca gacctgttag gcagacgtgt taatccctat
     6301 caggtgaaat atgcactcaa ggattctaga gccttgtctc tctcttattt gcagctggct
     6361 gtaaagacct taattgaaac agattatcac attaaaacag gtgtttacac aaaggattat
     6421 ctttttgacc ttgctctctt aaagctagta gcgcattctc agggaaatac tgacctctca
     6481 gacctatgag catcaatcaa attagttgaa agcctctatt ttttgagata agatagactt
     6541 atcataaagg aaaagaggaa agagacatga ccattacatt accggatctt ccgtacgcat
     6601 atgatgccct tgagccttat tttgacacag aaacaatgac gcttcatcat gataagcacc
     6661 atgccaccta tgtggctaat accaacactg ctttggaaaa atacccagag ctaggagaaa
     6721 atttagagga attattagca gatgtaagca gcattcctgc tgacattcgt caggctgtga
     6781 ttaataatgg cggtggccat ttgaaccatg cgcttttctg ggagctgctt tctccagaaa
     6841 agcaagaggt ttctgctgat gtcgcagcag ctattgatga cgcttttggt tcctttgctg
     6901 cctttaaaga gcaattcaca gcagcagcta cgggtcgttt tggctcaggt tgggcctggc
     6961 tggttgtgaa taaggctggt cagcttgaaa tcacatcaac tgctaatcag gacacaccaa
     7021 tctcagaggg caagcagcct attttagcac ttgatgtttg ggagcatgct tattacctca
     7081 attaccgcaa tgttcgtcca aattatatca aggccttctt tgaaatcatt aattggaaaa
     7141 aggtctcaga gttttaccaa gctgcaaaat aatagaagtc agttaccaat ctcagaagta
     7201 gattggtttt ttaagtgtgc taataaacta ctagtgttgg tggtaaaagc ctccaagtct
     7261 tttgaaaata ttctctaacg tgatagacaa tacgtgtaac gttcagagtg tatttgatag
     7321 cttagaagct ttataaaaag ccctgccatc tctctagcga atttacccac tagagagatg
     7381 atagagctgt tttttggtta ttggatctac ctcatacctc agctaggggg tcttgctggg
     7441 aaagctttga tgagcttgtt gataatggcg aagtaatttt ttaaaggctt tagccgctgc
     7501 tttcgttaat tgcttggagg atttgccatc tcggctaaaa atagggtgct gttgatcatt
     7561 ttgctgctct aaatctggta ctataaatgg actatcaagg tttatcattg ctgtttcaat
     7621 gaaatcaggc tcaaatagct caatgggttc aatatcaagc aatctatgca gatcattgtt
     7681 ttgattggca tagttaaagg aagacccatt gatgagacca ttttgacttg gctgttgagg
     7741 atctagggca gccaagaaat gaccagcctc tgataaaata aattctgagt gaaaatgaat
     7801 taaaatctta taattggctt gggggaaatt gtctgggtat gtgatttgga gctgattggc
     7861 tgtgtctaaa tgactagcta ccttattgtg gtatctggct gattcattaa gactataatc
     7921 agattcgtct agggtagcta ggtatctagc caaggcatca gcatctgttt ttcctgctct
     7981 cccataattg tttctaaccc attctatttg ctgcactgac aggacatagc gcagctgata
     8041 gagcttgcga ttgaaggtct gataaggaat atgctccaaa tgatcataat aaagctgaat
     8101 taatgatgct aattggtccc aaaaggcatc tgtcgggctt aaggacggac tgaattgctt
     8161 gagtaattgc tttgtttcag cgctttgccc acttaattcc tcgggcattt ttacatagct
     8221 caaaagtaag ctgaggtctc ttttagcttc aagcttatgt tgagcccttg gctgcctttc
     8281 ccacatgcga tgaaaagcag gagacccaat gatctgcagg ctctgataaa gctgctcaaa
     8341 gttatagctt gcttgcttag gcttgagatg gcctaggtag cccttttcaa tggcctcata
     8401 ggaccacccg tcctgtgcta gctttttggc ataatgcagc agatctttcc tgagctgaaa
     8461 ctgatcagat aggcttgagg gctgttgttt tatatgccgc ttttcaaagg aaataaccat
     8521 gtccttgtaa gcttggtggc tctgctcaaa ggccagcctt gcttgctcat gctttgcaaa
     8581 gctaacaaca aacagcacaa ataataaaaa catgagcccg ctgtgaatgt atttcatcat
     8641 taggctttac ttaacaaaca tggcatcacc aaagctaaag aagcggtaat gctcatcaat
     8701 ggcatgctta taggcttcaa ggacaaagtc acgacctgca aaagcagaaa ctagcatgac
     8761 aagcgttgac ttgggcagat ggaagttcgt tgaaaaagca tcaacaacct taaattggta
     8821 gcctggctta ataaaaatat tagtccaacc agaatctgct agaatttgcc cttggaattt
     8881 gctgccaatc gtttctagtg tgcgaataga agtagtacca acagcaataa tgcgtccacc
     8941 agcggcctta accttcctaa gggtttgggc ggcctcttca gatagcaggt agaattcaga
     9001 gtgcatgtca tgctcatcga tattatcgac agaaactggt ctaaaggttc ctaggccaac
     9061 atggagggtc aggtagacga ggtgtactcc tttggcttct attttttgca gaagttcctg
     9121 agtaaagtgt agtccggctg taggagcagc tgctgagcca ttttccttgg cgtaaacggt
     9181 ctggtagcgc tcagcgtctg ctagcttttc atggatatag ggcggaagag gcatttcgcc
     9241 tagagtctct aaaatctcta ggaaaatacc atcgtatgaa aactcaacga ttcgaccgcc
     9301 atgctctagc tcttgaatga cccttgcctt taggcgtcca tcaccaaagc tgatctgtgc
     9361 accggcttta agccgctttg cgggcttggc taaaacctcc cattggtctc cctgaatgtt
     9421 tttaagcagc aaaagctcaa catgcccatg tgtttccatt ttttcaccgt ataagcgggc
     9481 aggaaggacc cgagtattgt tcatgaccag tgcatctcct ggctctagtt gatcaatgat
     9541 atggtcaaag tggctatctg tcatggtgtg ctcttgatgg tcgataatca agagcttcga
     9601 gcgatccctt tgttcaagtg gtgtttgtgc aatcagctcc tctggtagct caaaatcaaa
     9661 atcgttggta ttcatcttaa ctcctttacc cttcttgtga ggctatttac aatcagccta
     9721 tttatcctta gagataaatc ctttctatta tatcacttgt ccctggctac gtcacctgtc
     9781 atggttatga gacacataga gatgattgat ggccttttac tccttattag ctagtgcttc
     9841 ttagctgacg acaggggata tgagattatg gcttgacaat aattggtata taccatataa
     9901 tagaatcaca aaaggtctat accaatcaaa aaggagaatc agatgaaaat tattcgtgta
     9961 caggatcagt tagagggtgg caaggttgct tttagcctat taaaggaaag cttggcaaaa
    10021 ggggctacaa ccttaggatt ggcaacaggc agcacaccga ttacctttta tcaggagctg
    10081 gttaatagtg atttagactg ttcagccttg accagtatca acttagacga atatgtcggg
    10141 ctgccggttg aaaatgatca gagctatgac tattttatgc gtgaccagct gtttaacgct
    10201 aagcccttta aggaaagctt tttaccaaac ggcttagctg atgacttaga ggcagaggtt
    10261 aagcgctatg atcaagttat cgcagagcac cctattgatt ttcagattct tggaattggg
    10321 cgcaatggtc atatcggctt taacgagcca ggaacctctt ttgcagaaaa gacgcatgtg
    10381 gtggatttgc aggcttcgac aattgaggct aatagtcgct tctttgctag tattgatgat
    10441 gtgccaaagc aggctatttc aatgggaatt gcttctatca tggcatcaaa aatgattgtc
    10501 ctattggcct ttggtaagga aaaggctgcc gctattaagg gcatggtatc aggtccagtt
    10561 actgaggctt tgccagcaag tgtattacag cagcacggta atgttgtggt tattattgat
    10621 gaggctgccg cttcagagct ggattagact attgctgatg gctaacagct agtctgctat
    10681 ccgttgtgct cttttgatac agtgtaggta tctggctaaa ggtttcttgc tgactttagc
    10741 aaaaaatctg atcagttatt aaaagaggct ctttggcctc ttttttagaa ttaaggtata
    10801 ttgtgataaa ctaatgctat gcgtttagat aaattattag aagtgacagg ctttggttct
    10861 agaaatcaag tgaaacaact catcaaagga aggtctgtct tgattgatgg gcaaccagct
    10921 agagctggtt gtcagagtgt tgattcaggt cttcaagtga taatggtaaa tggcaggcaa
    10981 ataaaggcat ttgctcatcg ctattacctg cttcataagc cagcaggggt tgtgtcagct
    11041 tgctctgata ggaagcacca aactgtcatt gatttgattc gtaaggagga tagagtggcc
    11101 aatctttacc ctataggccg cttagataga gatacaacag ggcttgtcct cttgacggat
    11161 aatggtccat tagggtttcg tatgcttcac ccgaagcacc atgtgaacaa gacctacctt
    11221 gtgactgtca atggctcttt ggctgctgat gcggtgcctt tctttgaaaa tggtgttacc
    11281 tttcttgatg gtactcgctg caagtctgcc gccttgcgga ttataaaggc tgatcaaatg
    11341 gagtcacaag cagaagtaac actctctgaa ggaaaatacc atcagatcaa gaaaatgttt
    11401 ttaagctatg gcttaaaggt cacacagctc aagcgaattg gttttgcaga aatagcgcta
    11461 ggggatttag ctgagggagc ttatcgtcag ctaacagtaa aagaaaaaaa gctcatcaag
    11521 acctatttaa cataaaatat tgttagattt gaagttgact gacaggttaa gtccagtgtt
    11581 tttcggatat atgctataga gagaacgata acaactggag acccctatgc taactgcctt
    11641 agaccaagat caaagagtca tctcgcttac agatggctct tccccctcac gcaagcaagc
    11701 ctttacctgt cctgcttgtg gagctgctgt acgcttgaaa aaaggaagaa ttatccgacc
    11761 ccactttgcc catattagcc taagtcattg ccaatacctg actgaaaatg aatcacatga
    11821 acatctcagg ctaaaggctg atctgtaccg tagcctatct cgctctgaga cagcagaggt
    11881 tgaggcctac ctgcctgatc taaatcaaat tgcagacctt ctggttaata agcacttagc
    11941 cttagaaatc cagtgtagtc agctaccaat caaaaggctg gagcaacgca gtagggctta
    12001 tcaggctaat ggctatcagg tgcgttggct cttaggaaga aagctttggc tgcaaaagcg
    12061 tctgacaggt ttacaaaggc aatgccttta tttttcttgg cagcttggct ttcatctttg
    12121 ggagctcgat gtggaacacc acctgatacg attgaaa
//
LOCUS       DARYNN010000057        11398 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.057, whole genome shotgun sequence.
ACCESSION   DARYNN010000057 DARYNN010000000
VERSION     DARYNN010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11398
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.057"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(72..2753)
                     /locus_tag="TVB59_001684"
     CDS             complement(72..2753)
                     /locus_tag="TVB59_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEL1010552.1"
                     /translation="MSKEQRHEAFYTQSEETVLAQLESSRKGLTSTEAQQRLAAYGRN
                     ELDEGEKRSLFMKFLDQFKDLMIIILVAAAFLSVVTEGMEGLTDAIIILAVVILNAAF
                     GVYQEGQAEAAIEALKSMSSPLARVRRDGHVIEVDSKELVPGDIVLLEAGDVVPADMR
                     LLEVNSLKIEEAALTGESVPVEKDLSREVSADAGIGDRVNMGYQNSNVTYGRGMGVVT
                     NTGMYTEVGHIAGMLANADETDTPLKQNLDNLSKILTYAILVIAAVTFAVGVFLRGQR
                     PLEGLMTSVALAVAAIPEGLPAIVTVVLSLGTQVLAKRNAIIRKLPAVETLGSTEIIA
                     SDKTGTLTMNQMTVEKVYTNGALQESSADIAFDNNTLRVMNFANDTKVDPAGKLIGDP
                     TETALVQFGLDHRFDVREALVSEPRVAELPFDSDRKLMSTIHKQADGRYFIAVKGAPD
                     QLLKRVTQIEENGDIRPITEADKQTILATNKDLAKQALRVLMMAYKYTEVIPVLETEV
                     VEAELIFSGLVGMIDPERPEAAQAVKVAKEAGIRPIMITGDHQDTAEAIAKRLGIIEE
                     DGVDHVFTGAELNELSDEAFQKVFRQYSVYARVSPEHKVRIVKAWQNEGKVVAMTGDG
                     VNDAPSLKTADIGIGMGITGTEVSKGASDMVLADDNFATIIVAVEEGRKVFSNIQKTI
                     QYLLSANMAEVFTIFLATLFGWDVLQPVHLLWINLVTDTLPAIALGVEPAEPGVMKHK
                     PRGRQSSFFDGGVKEAILYQGALQTILVLGVYGFALMFPEHTSYHDVHADALTMAYVT
                     LGLIQLVHAYNVKSVYQSIFTVGLFKNKLFNYSIPVAFVALMATVVVPGFNKFFHVTH
                     LTLTQWLVVIVGSLLMVVLVELVKAIQRSLGQDDKAI"
     gene            complement(3101..3487)
                     /locus_tag="TVB59_001685"
     CDS             complement(3101..3487)
                     /locus_tag="TVB59_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEL1010553.1"
                     /translation="MKIEINNKISYGQETELIKEIHTGDLRQKADATYLIYQNNNNER
                     VVIKFNAAELTMSRFSKPQSVMRFLANKKALIAIPTPVGIQQFLTDTSHFHLDHGQQT
                     VTLDYALLQPSTETAFAHYHLEIKWY"
     gene            3568..4869
                     /locus_tag="TVB59_001686"
     CDS             3568..4869
                     /locus_tag="TVB59_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEL1010554.1"
                     /translation="MNEKVFRDPVHNYIHVNHQLIYELINTKEFQRLRRIKQVPTTAF
                     TFHGAEHSRFSHCLGVYEIARRVTEIFEEKYADLWHKEESLVTMTAALLHDIGHGAYS
                     HTFETLFDTDHEAVTQDIITSPETEINAILTRYSPDFPDKVASVINHTYPNKQVVQLI
                     SSQIDCDRMDYLLRDSYFSAANYGQFDLMRILRVIRPVKDGIAFDLSGMHAVEDYIVS
                     RFQMYMQVYFHPASRAVELILQNLLKRAKALYPSQQDYFQKTAPGLIPFFEKSFTLAD
                     YLCLDDGVLNTYFQQWITSEDHILSDLSSRFINRKILKSVTFDQESQQDLERLRKLVE
                     SVGFDPDYYTGIHVNFDLPYDIYRPELENPRTQIEMIQKDGSRAELSQLSAIVKALTG
                     TSYGDRRFYFPKEMLELDDLFTSDKEAFISYISNGHFHFNN"
     gene            5094..5903
                     /gene="yidA"
                     /locus_tag="TVB59_001687"
     CDS             5094..5903
                     /gene="yidA"
                     /locus_tag="TVB59_001687"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEL1010555.1"
                     /translation="MSIKLVAIDIDGTLLTDDRRVTNDVFDAIQEAKAQGVHIVIATG
                     RPITGVISLLEQLQLNQKGDHVITFNGGLIQDTATGEEVVKELMTYDDYLDIEYLSRR
                     LGVHMHAITTEGIYTANRNIGKYTVREARLVDMPVFYRTPEEMADKEIVKMMMIDEPN
                     LLDEAIKQIPQAFYDTYNIVKSTPFYLELTPKTVSKGTAIGHLAKKLGIDMSQTMAIG
                     DAENDRAMLEAVANPVVMENGAPELKKLAKYITKSNNDSGVAHAIRKWVLN"
     gene            5903..7117
                     /locus_tag="TVB59_001688"
     CDS             5903..7117
                     /locus_tag="TVB59_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II:glycine glycyltransferase FemX"
                     /protein_id="HEL1010556.1"
                     /translation="MYTYKIGISAKEHDQFVLSHPQVNLLQSAHWAQVKDNWEHELIG
                     FYQDDKQVAAAACLIKRLPLGMTMIYIPRGPIMDYSDFELVNFVMTSLKAYGKSKRAL
                     MIKYDPSLFISQALIGEERKDNDFTLSIIDFLKTIGVEWTGRTKELEQTIQPRFQANI
                     YAKDFKLQSLSKKARQSIRTAQNKGVEIIIGSTELLEDFSALMKKTEERKHISLRGIS
                     YYDKLMTTYANQAYITMARLNLPKQKALIQQQLEEALSNQQAFTQHSKPGKVAENQNT
                     IKRLEKELAFLDKEIQAGKSLVPLAATLTLIYGQTSENLYAGMDNDFRQYQAALLTWY
                     HTAEEAFKRGCQWHNLGGVENQLDGGLFQFKARLNPAIEEFAGEFSIPVGPISKVAMI
                     AYNLRKKLRSNP"
     gene            7117..8352
                     /locus_tag="TVB59_001689"
     CDS             7117..8352
                     /locus_tag="TVB59_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyltransferase"
                     /protein_id="HEL1010557.1"
                     /translation="MALDIIDKETFGSFCSQMKYKSFIQSIEMAELLQKRGYQTQYLA
                     ISDQKNIKIAAILYSIPMTGGLRMEINSGPVVADTTYTTAFYKALQDYAKQQGALELV
                     IKPYDTYQTFTSDGHPNDDEKPELIKTLTELNFTHDGLLTGYHNGEGDWHYVKDLSGL
                     TSANVINSFSKKGKALLKKAKTFGIKLHKLNRDELTQFKEITAATSSRRDYTDKSLSY
                     YQDFYDSFGDSCEFMVATLNFDDYLTNLEHSQDKLKQRISKLEADLVKKPKSEKKQNQ
                     LRELSSQFDTFQVRIAEAQELIVKYGKKDIPLAGSLFVYTPQEAVYLFSGSYPEFNRF
                     YAPALLQEHVMLRAIEKKISCYNFLGIMGEFDGSDGVLRFKQNFNGYITRKMGTFRYY
                     PKPFKYKAIQAIKTMLGRS"
     gene            complement(8561..9319)
                     /locus_tag="TVB59_001690"
     CDS             complement(8561..9319)
                     /locus_tag="TVB59_001690"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEL1010558.1"
                     /translation="MSRKPIIAGNWKMNKNPQEAKAFVKAVVSKLPSNDLVDVAVAAP
                     AVDLVTTIEAAKDSVLKVAAQNCYFENSGAYTGETSPKVLADMGADYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGLTPIICCGESLETYEAGKAVAFVGAQVSAALEGLSAEQV
                     ASLVLAYEPIWAIGTGKSATQEDAQSMCKAVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NIKEYMACPDVDGALVGGASLEADSFLALLDFVN"
     gene            complement(9585..10781)
                     /gene="tuf"
                     /locus_tag="TVB59_001691"
     CDS             complement(9585..10781)
                     /gene="tuf"
                     /locus_tag="TVB59_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEL1010559.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETATRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIIMELMDTVDSYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGTVRVNDEIEIVGIRDEIKKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGI
                     VSEIEA"
BASE COUNT         3421 a         2582 c         2262 g         3133 t
ORIGIN      
        1 ttatttttta actatgaacg tcagaccttt ttgttagttt gaaagtgttc ttatcttttt
       61 gctaatgacg cttaaatcgc tttgtcatct tgaccaagtg agcgctgaat agccttgaca
      121 agctcaacaa gcacaaccat caagagactt ccaacaataa caactagcca ttgtgtaagg
      181 gtcaaatgag tcacatgaaa gaatttgtta aagccaggga caacaactgt agccatcaag
      241 gcaacaaagg ctactgggat agaatagtta aataatttat tcttaaataa tccaactgta
      301 aagatagact gataaacgga cttaacatta taagcatgca ccagctgaat gagaccaagt
      361 gttacataag ccatcgttaa agcatcggca tgcacgtcat ggtagcttgt atgctctggg
      421 aacatcaagg caaagccata aacaccaagc actaggattg tctgaagggc accctgatac
      481 agaatagctt cttttacacc accgtcaaag aagcttgatt ggcgtccacg aggcttgtgc
      541 ttcatgacac caggctcagc aggctcaaca ccaagagcga tcgctggcag cgtatctgtt
      601 accagattaa tccaaagcag gtgaaccggc tgaagcacgt cccagccaaa taaggtagca
      661 agaaagatcg taaagacctc agccatgttg gcagaaagca ggtactgaat tgttttttga
      721 atgtttgaaa agaccttacg tccttcttca acggcaacaa taatagttgc aaagttatca
      781 tcggcaagga ccatatcaga agctccctta gaaacctctg tacctgtaat ccccatacca
      841 ataccaatat cagctgtttt aagagacggc gcatcattga caccatcacc agtcatagca
      901 acaaccttac cttcattttg ccaagcctta acgatacgaa ccttatgctc tggagataca
      961 cgcgcataaa cagaatattg tctaaagacc ttttggaagg cttcgtcaga cagctcattg
     1021 agctcagcac ccgtaaagac atggtcaaca ccatcttctt cgataatgcc aagacgcttg
     1081 gcaatagctt ccgctgtatc ctggtggtca ccagtaatca tgatcggacg aataccagcc
     1141 tccttagcca ccttaacagc ctgagccgct tcagggcgct ctgggtcaat catgccaaca
     1201 agccctgaga aaatcagctc tgcttcgacc acctctgttt caagtactgg aatcacttct
     1261 gtgtatttgt aagccatcat caagacacga agggcttgct tagccaagtc cttattagta
     1321 gccagaatcg tttgcttatc agcctctgta atcggacgaa tatctccatt ttcttcaatt
     1381 tgagtgacac gttttaacag ctggtcagga gcacccttaa cagcgatgaa gtatctgcca
     1441 tcagcttgct tgtgaatggt tgacatcagc ttacggtcag aatcaaatgg taattctgcc
     1501 acacgaggtt ctgaaacaag agcctcacgc acatcaaagc gatgatctaa gccaaattgc
     1561 accaaggcag tctctgtagg atcaccaatc agcttacctg ctggatcaac cttagtatca
     1621 ttggcaaaat tcatcacacg aagggtattg ttgtcaaagg caatatcagc tgatgactct
     1681 tgaagtgccc cgttagtata aaccttttca actgtcatct ggttcatggt caaggtacca
     1741 gttttatctg aggcgataat ttcagttgaa ccaagggttt cgaccgcagg caatttacgg
     1801 ataatagcgt tacgctttgc tagcacctgt gttccaagag aaagcacaac cgtaacaata
     1861 gctggaagcc cctctggaat ggcagcaacc gcaagcgcca ctgatgtcat caagccttca
     1921 agtgggcgct gaccacgtaa aaagacacca actgcaaagg tcacagctgc aatcacaaga
     1981 atagcatagg ttaaaatctt agatagattg tcaaggtttt gctttagcgg tgtgtctgtc
     2041 tcatcagcat tagccagcat gccagcgata tggcctacct cagtgtacat accggtgttt
     2101 gtgacaaccc ccataccgcg tccataggta acgtttgagt tttggtagcc catgttaaca
     2161 cgatcaccaa taccagcatc agcagaaacc tctcttgaca ggtccttttc aactggaact
     2221 gactcaccag taagagcagc ttcctcaatt tttaaggaat tgacctctaa caaacgcata
     2281 tcagctggca ccacatctcc tgcctctagc aggacaatgt cgccagggac aagctcttta
     2341 gagtcaacct caatcacatg accatcacga cgcacacgtg ctaagggact agacatggat
     2401 tttaaggcct caatcgctgc ctctgcctgc ccttcctgat aaaccccgaa ggctgcattt
     2461 aagataacaa cagctaaaat aatgatggca tctgtcaagc cctccatccc ttctgttacc
     2521 acagaaagaa aggccgctgc aaccaaaata ataatcatca aatccttaaa ctgatcaagg
     2581 aatttcatga acaggctgcg cttttcaccc tcgtcaagct cattacgccc ataagctgct
     2641 aggcgctgct gtgcctctgt actcgttagc cccttacgac tagactctaa ttgagctaat
     2701 actgtttctt cactttgcgt atagaacgct tcatgtcttt gttctttcga caaattggtc
     2761 cctccttggt ctttttatgc tttattcaac taaaaagacc tgtttatttt tcttaaacaa
     2821 gtctcgctgt ttcagattgt accggaaatc gaaattccgt attgacgaca caatcacggc
     2881 taaccgtctg ctactccctt gatatagtca ctattataat aaaatgatga ccaaaaaaca
     2941 agaaaaaaac aaggaaatat tttttaaaag ccccaaatca tctgatgatt ttcagagcaa
     3001 aggtaactga tgaccaagct tagactatca ttaccgagat acagacagca gacacaggct
     3061 gtcatcttag gagactaaca aaggacttcc tctgctgaga tcaataccac ttgatctcca
     3121 aatgataatg agcaaaggcc gtctcagtgc tgggctgtaa taaagcataa tctagggtca
     3181 ctgtctgctg gccatgatcc aagtgaaaat ggctcgtatc tgtcaaaaat tgctggatcc
     3241 ctacaggcgt cggaatagcg atcaaggctt ttttgttagc aagaaacctc atcacagact
     3301 gaggctttga aaagcgactc atcgttagct cagcagcatt gaacttaatc actacccttt
     3361 cgttgttatt attttgataa attagatagg tagcatctgc cttttgtctc aaatccccag
     3421 tatgaatctc cttgattagc tctgtttcct gaccatagct gatcttgtta ttaatttcaa
     3481 tcttcatgat atcttctttc tcttgagttt tgctcgtcta ttctaccaat ttctgaccat
     3541 tttcgcaatt tctgctataa tagaagcatg aatgaaaaag tatttcgtga ccctgttcac
     3601 aactatatcc acgttaatca tcagctcatt tacgagctaa tcaataccaa ggaatttcaa
     3661 cgactaaggc gaattaagca ggtgccaaca acagccttta cctttcatgg tgccgagcat
     3721 agccgctttt cacactgtct tggtgtctat gagattgctc gccgtgtcac agagattttt
     3781 gaagaaaagt atgcagacct ttggcataag gaggagagtc ttgtaaccat gactgctgcg
     3841 ctcctgcatg atattggcca tggtgcttac tcgcacacct ttgagaccct atttgatact
     3901 gatcacgaag ctgttactca agatatcatt accagtccag aaacggaaat taatgcgatt
     3961 ttgacgcgct actctcctga ttttcctgac aaggtagcta gtgttatcaa ccacacttac
     4021 cccaataaac aggtagtgca gctgatctct agtcaaatcg actgcgatcg catggattat
     4081 ctgctgcgcg actcttactt ttctgcggct aattatgggc aatttgacct aatgcgcatt
     4141 cttagggtta ttcgacctgt gaaagatggc atagcttttg atctcagcgg tatgcatgcc
     4201 gtagaggatt acattgtcag ccgctttcaa atgtatatgc aggtttattt tcaccctgcc
     4261 agtcgagccg tcgagctgat cctacaaaac ttgctgaagc gtgctaaggc tctctatcct
     4321 agccagcagg actatttcca aaagacagcc cctggtctca ttccattttt tgaaaaaagt
     4381 ttcacgcttg ctgattatct ttgcttagat gatggtgtgc tcaataccta tttccagcaa
     4441 tggattacta gtgaggacca tatcctgtca gacctgtcta gtcggtttat caatcgaaaa
     4501 attttaaaat ctgtcacctt tgaccaagaa tcacaacagg atttagagcg cttgcgaaag
     4561 cttgttgagt cagttggttt tgatcctgat tattatacag gtatccatgt caattttgac
     4621 cttccttatg atatttaccg tcctgagctg gaaaatccaa gaacccaaat tgaaatgatt
     4681 caaaaagatg gcagcagggc tgagctatcc cagctctctg cgattgtcaa agctctcaca
     4741 ggcacaagct atggtgatag acgcttttat ttcccaaagg aaatgttaga gcttgatgac
     4801 ctctttacat cagataagga agcctttatc agctatatct ctaacggaca ctttcatttt
     4861 aacaactaag gaccagccaa ggtccttttg gctttttcat cacgctctag atttaaaatg
     4921 gtatattacc cgataaggac agctagagct ctgacaagca caagccacca aacacagcag
     4981 agcctttaat attgccaaaa tctcttttgt tttcatgaca aaagaaccta tttttagtaa
     5041 gatagaaggt ggcaaatcat tgattacaaa tcagaacaac caaggagaat tccatgtcta
     5101 tcaaacttgt tgccattgat attgatggca ccttactcac tgacgatcga cgcgttacta
     5161 atgacgtttt tgatgccata caggaggcca aggcccaagg agtgcatatc gtcattgcta
     5221 cgggacgtcc cattactggg gtcatctcat tattagagca attgcaatta aatcaaaagg
     5281 gagatcatgt catcaccttc aatggtggac tgattcagga cactgcaacc ggtgaagagg
     5341 tggttaaaga gctgatgacc tacgatgatt acctcgacat agaatattta agccgcaggc
     5401 taggcgttca catgcatgcc atcacaacag agggcatcta tactgctaac cgaaatatcg
     5461 gcaaatacac tgtacgagaa gcaaggcttg tggacatgcc tgttttttat cgaacacctg
     5521 aggagatggc tgacaaagag atcgtcaaaa tgatgatgat tgatgagcca aaccttttag
     5581 atgaggccat caaacagatt cctcaagcct tctatgacac ctacaatatt gtcaaatcaa
     5641 caccttttta tctcgaatta acaccaaaaa ctgtcagcaa gggcactgct attggtcacc
     5701 ttgccaaaaa gcttggcatt gacatgtccc aaacgatggc aatcggcgat gctgaaaacg
     5761 atcgagccat gcttgaagcg gttgctaacc ctgttgtcat ggaaaatggg gctcccgagc
     5821 tgaaaaagct ggccaaatac atcaccaaat caaacaatga cagcggcgta gcgcatgcta
     5881 ttcggaagtg ggtattaaac taatgtatac atataaaatc ggaatttcag ctaaagagca
     5941 cgatcagttt gtcctatcac atcctcaggt caatctgctg caaagcgctc attgggctca
     6001 ggtaaaggat aactgggagc atgagctcat tggtttttac caggatgaca agcaagtcgc
     6061 tgctgctgct tgccttatca agagactccc cctaggcatg accatgattt acattcctcg
     6121 agggccgatt atggattatt ctgactttga gttggttaac ttcgtcatga ctagcctaaa
     6181 ggcttatggt aaatccaagc gagctctcat gattaaatac gatccttcct tgtttatcag
     6241 tcaggcctta ataggtgaag aaagaaagga caatgacttc accctctcca ttattgattt
     6301 tttaaagacc atcggtgttg aatggactgg caggaccaag gagcttgagc aaacgattca
     6361 gccccgcttt caggccaaca tttacgccaa ggactttaag ctccaaagct tatcaaaaaa
     6421 agccagacag tctatccgaa ctgctcaaaa taagggagtc gagattatta ttggctcaac
     6481 agagctactt gaagacttct cagcactgat gaaaaagact gaggagcgaa aacacatttc
     6541 tttgcgtggc atttcctatt atgacaaatt aatgaccact tacgctaatc aggcttacat
     6601 taccatggct agattgaacc ttcccaagca aaaagcgctc atacagcagc aattagagga
     6661 agccttgagc aatcagcagg cctttaccca gcacagtaag ccaggtaagg tcgcagaaaa
     6721 ccaaaatacc attaaaaggc ttgaaaagga attggctttt ctagataagg aaatacaagc
     6781 aggtaaaagc cttgtacctc tagcagctac cctgacactg atctatggac agacctctga
     6841 aaacctatac gcaggtatgg ataatgactt tcgccaatat caggcagccc tcttaacctg
     6901 gtatcatacc gcagaagagg cctttaagcg cggttgtcaa tggcacaatt tagggggcgt
     6961 tgaaaaccaa ttagatggtg ggctgtttca gtttaaagca agactaaacc cagctatcga
     7021 agaatttgca ggagaattca gcattccagt tggacctatc tcaaaggtgg ccatgatagc
     7081 ctacaatttg agaaaaaaac taaggagtaa cccttaatgg ctttagatat cattgacaaa
     7141 gaaacgtttg gctcattttg cagtcaaatg aagtataaat ccttcattca atctatagaa
     7201 atggcagagc tgctgcaaaa gcgtggttat cagacacaat accttgcaat cagtgaccag
     7261 aaaaacatta agattgcagc cattctctac agtataccaa tgaccggcgg cttacgcatg
     7321 gaaatcaact caggtccagt agtggctgat acgacctaca caacagcctt ttacaaagcc
     7381 ttacaggact atgccaagca gcagggagca cttgagctag tcatcaagcc ctacgatacc
     7441 tatcagacct ttaccagcga tggtcaccca aacgatgatg aaaagccaga gctgatcaag
     7501 accttgacag agctcaattt tacacatgat ggcctgctaa caggctacca taatggtgaa
     7561 ggagattggc attatgttaa agatttaagc ggattgacct ctgctaatgt catcaattcc
     7621 ttcagtaaaa agggcaaggc cctgctaaaa aaagccaaaa cctttggcat taagctacat
     7681 aagctcaatc gtgatgagct aacacaattc aaggaaatta ctgctgctac atctagtcga
     7741 agagattata ccgacaagtc tttatcttat tatcaggatt tctatgatag ctttggggat
     7801 agctgtgaat ttatggttgc aaccctcaat tttgatgact acctgaccaa tctagagcac
     7861 agtcaagaca agctaaagca gcgcattagc aaattagagg cagacctagt taaaaaacca
     7921 aaatcagaaa aaaaacaaaa tcaactacgg gaactctcca gccaatttga tacctttcaa
     7981 gttcggatag ctgaagcaca ggagttaatt gtcaagtatg gcaaaaagga cattcctcta
     8041 gctggtagtc tctttgttta caccccgcag gaggctgtct atctcttttc tggctcctat
     8101 ccagaattta acaggttcta cgcgccagcc ctattacagg aacatgtcat gctaagagcg
     8161 attgaaaaga aaatcagctg ctataatttt cttggtatca tgggcgaatt tgatggctct
     8221 gatggtgttt tacgctttaa gcaaaacttt aacggctata tcacacgaaa gatgggaacc
     8281 tttaggtatt atccaaagcc cttcaagtac aaagccatac aggccatcaa gacaatgctt
     8341 ggtcgcagct aagtcaagct agtggctaag cagcccttta agccttccaa tggctattga
     8401 ccacaataat aaatccttga ttgtcttact cagaacccct ttagtaaact ttccaaccta
     8461 aaaataaggt ataggtgatc ccatgctcaa gaaggctatc aagcaaacca aaagctcaag
     8521 gaattaaccc ttgagctttt tagctatatt ataattgtca ttagttgaca aaatcaagca
     8581 aggcaaggaa gctatctgct tctagtgatg caccaccgac aagagctccg tcaacatccg
     8641 gacaagccat gtactcctta atgttttcag gcttcacaga accaccatac tgtacacgaa
     8701 ccttgtctgc cacctcttga ccaaagtcag cagcaaccac atcgcgaaca gccttacaca
     8761 tgctttgagc atcttcttga gtggcagatt taccagtacc gatagcccag attggctcat
     8821 atgccaatac caatgaagca acctgctcag cagatagccc ctctagagcc gcagacacct
     8881 gtgcaccaac aaaggctact gccttgccag cctcataggt ctcaagagac tcaccgcagc
     8941 agataattgg tgttaagcca ttagcaaaga tggcttttgc ttttttatta atatcttcgt
     9001 ctgtttcgtg gaagtaatca cgacgctcag agtgaccaat caccacataa tcagctccca
     9061 tgtcagcaag aaccttagga gaggtttcgc ctgtataagc gcctgaattt tcaaaataac
     9121 agttttgcgc agcaacctta aggacagagt ccttagcagc ctcaattgta gtgaccaagt
     9181 caacagctgg tgctgctact gcaacgtcaa caagatcgtt tgaaggtaat ttgcttacta
     9241 ctgccttaac aaaggctttt gcctcttgag gatttttgtt cattttccag ttaccggcaa
     9301 taattggttt acgtgacatt tcacatacct cttctttttt tatttacatc tactattcta
     9361 gcacaatttc tatgctaata aaagaaaatg gctgactttt aggaatattt tcacaaagaa
     9421 aagagtattt tctgaaacca ttttcaaacg ataaggctta tcgattagct aagcagaccc
     9481 gctaagtcct catctttata aacagagcaa aaagagccct taaaacaagg gctctcacaa
     9541 ttaagctgtc tgactttaat cgttatctgg gaacttaatc aaaattaagc ttcgatttct
     9601 gaaacgatac ctgaaccaac agtacgtcca ccttcacgaa ttgagaatgt agtaccttgt
     9661 tctacggcga ttgggtggat caactcaacg tcaatagtca cgttatcacc aggcataacc
     9721 atttctgtac ctgctggaag ctcgattgaa cctgttacgt cagtagtacg gaagtagaat
     9781 tgtggacgat agttgttgaa gaatggtgtg tgacgtccac cttcttcttt agtaaggata
     9841 tatacttcac ctttaaattt agtgtgtggg ttgatagaac ctggcttagc aataacttga
     9901 ccacgttcga tttcatcacg ttgtacacca cgaagaagaa caccaacgtt gtcccctgca
     9961 agaccttcgt caagctgttt acggaacatt tcgacaccag taacaactgc ttttttgatc
    10021 tcgtctctga taccaacgat ttcgatttcg tcgttaacac gaacagtacc gcggtcgata
    10081 cgtcctgaag caacagtacc acgtccagtg attgagaata cgtcctcgac tggaagaagc
    10141 aatggcttgt ctgtgtcacg ttctggttct ggaatgtatg aatcaacagt atccatcaat
    10201 tccatgatga tatcttcgta tttgctgtcg ccttcaagag ccttaagcgc tgaaccttgg
    10261 ataactggaa ggtcatcacc tgggaaatca tattctgaaa gaaggtcacg aatttccatt
    10321 tcaacaagct caagcaattc ttcatcgtca acaaggtcaa ccttgttcat gaacacgata
    10381 aggtgcttaa caccaacctg acgtgaaaga aggatgtgct cacgagtttg tggcattggt
    10441 ccgtcagttg aagcaactac aaggatagct ccgtccattt gagcggcacc agtgatcatg
    10501 tttttaacgt agtccgcgtg tcctggtgcg tcgatgtgcg catagtgacg tgtagcagtt
    10561 tcgtactcaa cgtgtgcagt gttgatagtg attccgcgtt cgcgttcttc tggagcagca
    10621 tcgattgaag cgtagtcttt tggttggtta actgagcttg gtagacgacg tgcaagaaca
    10681 gttgtgattg cagctgttaa agtagtttta ccatggtcaa cgtgtccaat tgtaccaatg
    10741 ttaacgtggg gtttactacg atcgtatttt tcttttgcca ttttaggaaa agcctccaat
    10801 aaaatatatt ttatagatag acggtaggca atacagtcta actttacctt actattgtag
    10861 caaattataa ggaaattgca agcagtaagt gaggaacttt aacggattta tcgttatccc
    10921 tgatttcaac aaccctagca tacaaaaaag gaaagagttt tcgtcttctc ccaggcaatc
    10981 cgctctttac cgttttttgc ttttcaaggc tctaggcatt tgcatacttt tggaggagag
    11041 ttgaattgtt aagagataat gcattcggag atctataaat cataggcagg acataccgat
    11101 ccaaaactaa gatagtggag acttgatggt ccatgacaga cgcgcgaaac agctatttcc
    11161 gaatgataat atagatgaga gtagacactt tcaacgttct tcctatagta aaagctatgc
    11221 aaaatcctac atattcttga aatagctgaa cattgaaata caggaagctt tattttattg
    11281 ctaaaaatct ttcatgtgtc tatcgtggtc gatgatcgca gagttagctt gttaatattt
    11341 tctatctttt ttattatatt ttgttaattt tataatctat ttaactattt taaaaatt
//
LOCUS       DARYNN010000058        11281 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.058, whole genome shotgun sequence.
ACCESSION   DARYNN010000058 DARYNN010000000
VERSION     DARYNN010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11281)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11281)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11281
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.058"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            160..747
                     /locus_tag="TVB59_001692"
     CDS             160..747
                     /locus_tag="TVB59_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010560.1"
                     /translation="MIDKIKNILFDVRLSANKIENEIIFYNGFPEDSVSLSFAGNKCI
                     IEEIHRDNRIRLMETTSEYHAILYCVAILDQIFNTSKNIKITREIKEYIQEGNIIAAE
                     QLLSEKLDPTLFSLGSVEKDKLTLVKENNAYSLIFNDVQILTDLSSLRAYIVLFNYTK
                     KLERAKELYARALHDLPDCKLEFNQFVEYYLIGRN"
     gene            1183..1602
                     /locus_tag="TVB59_001693"
     CDS             1183..1602
                     /locus_tag="TVB59_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622467.1"
                     /note="This protein contains a domain related to
                     Tuberculosis Necrotizing Toxin, which is the C-terminal
                     effector domain of outer membrane channel protein CpnT,
                     and which has a lethal NAD+-glycohydrolase activity;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycohydrolase toxin TNT-related protein"
                     /protein_id="HEL1010561.1"
                     /translation="MVDNLGNPITEQVTLKAGQIIDRYGSSSGRFTSPIENGVTLPFN
                     KRGLPYPEGYQDYYKYELVMDLTKKNIVNAYYQSEEIIRKQISVEMKKWNLSFDDLAN
                     IQKGEITKVFGQGGGIQIKFPTGVGIYKKMGLLKEIN"
     gene            1603..1926
                     /locus_tag="TVB59_001694"
     CDS             1603..1926
                     /locus_tag="TVB59_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009568641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010562.1"
                     /translation="MDNTNILNWKKDIEEAIKNRGFESLHYVLFDEEKRLPWAFHLYQ
                     KNGKFYVEGRDERSYIIGHSREYRKFDDAKHELLKKLELVIESNRLKKQLGEPTEYPS
                     PLWNE"
     gene            2185..2814
                     /locus_tag="TVB59_001695"
     CDS             2185..2814
                     /locus_tag="TVB59_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010563.1"
                     /translation="MTTLAGMSPEDSQRYIQWHKYAKAGLSPSDRVRILEISEKAPKI
                     EYLPGKTSDSILAISKGDRPNVEKVYSPDYIGFHRKQFDNGATRFQKFKPNVDYQDGL
                     VGDDLGNSFWLSTKDADIIQEIGKGNNRLYETLLGFDEGYLEDGPLYRLDVSPEVVSQ
                     KGVSIPSGNEKGANSWWRPGGRTYPGNIPEGVMQGISTKKGDHTWHAVN"
     gene            2796..3218
                     /locus_tag="TVB59_001696"
     CDS             2796..3218
                     /locus_tag="TVB59_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010564.1"
                     /translation="MARSQLEWEDVSQYEEVKGYGQRVWKHQGKYYFVAEEGGIAVQR
                     VVYELPYDLFELLESGERSLGDVHSKLQDGNWPPTEEEKKQSHRKFVIDTPTALIADP
                     TSVSLFSEEELSKLVPIAEQQWIDWKGKLPDDYVSPLK"
     gene            3477..3881
                     /locus_tag="TVB59_001697"
     CDS             3477..3881
                     /locus_tag="TVB59_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010565.1"
                     /translation="MSKNYTEADVAKLTELTTHNAKTKTALLGYYEANSVTSYEQIAH
                     QNKLTYFDAGSDGWNAMSRVDSKLAQRVNREFLIKQIEKRKTFILTSNPYTAQSIADV
                     SGIGKSYAKEIQILAENGYNIEKFERFWRAYK"
     gene            3878..4306
                     /locus_tag="TVB59_001698"
     CDS             3878..4306
                     /locus_tag="TVB59_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010566.1"
                     /translation="MSEEQYLPVKESLGYRNLKIALMNVFSIDLDKFTIIEGEFENFG
                     FHLNYNNKEIIIWITSTGKNRQFEYGEGGQLMISLPNPKYPDRSFLDRVTLESLLTDT
                     EKIEAVDYAFGRYEHRLEIALAILKDYLDSDEAKVLLKNE"
     gene            4299..4712
                     /locus_tag="TVB59_001699"
     CDS             4299..4712
                     /locus_tag="TVB59_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010567.1"
                     /translation="MSEQYLSIKESLGYKNVKQALWTIFSANLDEISIHEGEDENFNF
                     VFTYKNCEMMMGIYDTGKNIQFQAGEGGLFSVSLPNPKYPEQSFQKIVSLSYLISDKN
                     VSENIRWCLGLDLKSVEYVMRVLKDYLDQKCEEEQ"
     gene            4975..5367
                     /locus_tag="TVB59_001700"
     CDS             4975..5367
                     /locus_tag="TVB59_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623140.1"
                     /note="This protein contains a domain related to
                     Tuberculosis Necrotizing Toxin, which is the C-terminal
                     effector domain of outer membrane channel protein CpnT,
                     and which has a lethal NAD+-glycohydrolase activity;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycohydrolase toxin TNT-related protein"
                     /protein_id="HEL1010568.1"
                     /translation="MTPAFLKTGDLLDRYGESGGTFTSPIVDRKVIPFNKRGLPYPED
                     YQNYHQYKVLKDINMENVEKGYHNLSDSRKKELNLLMNRFDFSLVDIATPQKGMIDLV
                     FGSGGGIQIKLGTSVSWYEKLGLIKEIK"
     gene            5368..5691
                     /locus_tag="TVB59_001701"
     CDS             5368..5691
                     /locus_tag="TVB59_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010569.1"
                     /translation="MKNLDHQKAELLEAVHQLGYDSLRYSIFSKERPGEWETVIEYDN
                     SQGLYVVYATMDRASYNKKLTFETFQEAKEKFLEKLRLDIQINRYYVEEGMPVNYDSP
                     LWSKN"
     gene            6004..6474
                     /locus_tag="TVB59_001702"
     CDS             6004..6474
                     /locus_tag="TVB59_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEL1010570.1"
                     /translation="MAYSKEIIAYLVRSGVAKELARDISQDVLLKMLESDLALPPEKI
                     RAWMYRVAVRKYIDRYRRDKAYLDILQRDFFHQERVVEFDHPNYEPLYTAVNELPEKY
                     RWVLSFYYFQDLSVKEMASLLHWSVSSVKVNLMRGRRCLKEKLKKAGYTYDDFN"
     gene            6458..7551
                     /locus_tag="TVB59_001703"
                     /pseudo
     CDS             6458..7551
                     /locus_tag="TVB59_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623137.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="anti sigma factor C-terminal domain-containing
                     protein"
     gene            complement(7845..10991)
                     /locus_tag="TVB59_001704"
     CDS             complement(7845..10991)
                     /locus_tag="TVB59_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010571.1"
                     /translation="MKLKKIIALACVGILTLHQLSPAIVYATTDTSDGIAATVNAGDT
                     AAPSAEAKLSQLMTDTQALFTDNSCSKLASGVTQEKIDTLKQKATDSTEPEKEQILGL
                     LDKAASLLQQFTLQGLGNGVFAQLYFYADGSYTASLVTKRGQPHSYFSTNYATITILN
                     NKKETVYSKEYAGNVSQVAQTEELELKEGYYLIINKQEPNRFYTNHNDALKQNNTNPY
                     TYVVRDGQLERIDDSNRTLRFLGLGNAEYATLRVDYNASTLTLKTKQTKPHVYFSGSY
                     EKLEVLDTENQVIYTKDFIGTQVLEAKTETIPFKVGYKIRLTGSEHHTRVKFYDDYAV
                     EAPLTLSKNQATLKLLDHSLELMRSKTGSELESEVLTLFTDESTSKLASGVTQEKIDA
                     LRKKATDSTEPEKEQILSLLDKAASLLQQFTLQGLGNGIFAQLYFYADGSYTASLVTK
                     KGQPHSYIANNYATLTILNEKKETVYAKEYVGNVSQTAKTESLTLKEGYYLVITKQEP
                     NRFYTNHNDALKQNNTNPYTYVVRNGQLERIDDSNRTLRFLGLGNAEYATLKVDYNAS
                     TLTLKTKKAKPHVYFSGTYEKLEVLDLKDKVVYTQDFIGNQALTAKTETIPFKVGYKI
                     RLTGSEHHTRVKAYDEENKAVSLSLPKNKAEIRITKGGLASVFALEAKATNTLVQAVE
                     KRLTKEKIEDFKKQDDKHKAFIDWLLKDNEAMQLYLGAGYAHSAAQGGMSSYQFKNTY
                     NLTNELEALELWFKIWDKYETSHQGIQLKMAIAVALEFNKPVGAWYNESRKIDPLERF
                     ATFAEAEQGNILFEDFYSLTVEQIRNVVNAKITDEDMKWLRQYVETNKPAMINRNDIT
                     KGYSLISYVMTNPETGVSVQSSGFYGPNPTIKEVIKYGGVCGAMSKLSSVLAQAYGVP
                     AFPIGQPGHCAYIYLNADHTYQLGYDVSGWTGCGNYNTTLPYVQIHNVYSLNIDAYNA
                     SEYERYKAEAATDKETKLNHLDAALKAEPLNYKAWNDKLALVASDQTAYQSTLNDMKS
                     ALKDYPVIINNLEKDTKQ"
BASE COUNT         3571 a         1887 c         2424 g         3399 t
ORIGIN      
        1 tcagaggata ctatgtttat ttgagtatat gctggtgagg tttcagatca atttgtgaag
       61 tataaaccta atggagttga taaatatagt attcaagagc taatggatat ggttttttag
      121 atgacataac tgatttggtg aagaaaggag aaattagaat tgattgataa aataaaaaac
      181 attctttttg atgttaggct gagcgcaaat aaaatagaaa atgaaataat attttataat
      241 ggctttcctg aagatagtgt atctttatca tttgcgggta ataaatgtat cattgaagaa
      301 attcatagag ataatagaat caggttaatg gaaacaactt cagaatatca tgctatttta
      361 tattgtgttg caattttgga ccagatcttt aatactagta aaaatatcaa gattacaaga
      421 gaaatcaaag agtatataca ggaaggaaat attatagcag ctgagcagtt gctctcagaa
      481 aaattggatc ctactctttt ttcattaggg tctgtggaaa aagataaatt aacccttgta
      541 aaagaaaata atgcctatag tttaatattt aatgatgtgc aaattctaac tgatttaagt
      601 tcattacgtg cttacattgt tttatttaat tacactaaaa aacttgagag agcaaaagaa
      661 ttatatgcta gagcactaca tgacttgcct gattgtaagt tagaatttaa tcagtttgta
      721 gaatattatt tgataggaag gaattaataa aagaactatt gaaataccat atggcatttt
      781 gagttcagat gcccagtcat ggcaggaggc agcgaacaag atgctcagcg agctacatta
      841 gtaggcaata tcctaggagg attcgccgcc tcaagcgtcg ccagacggtt cagcttgaat
      901 gagccaatag cagctagggt gacgaaaccg acctacagcc gccggcagct tttgaagaac
      961 cttgagaaca gcaggctggc aagagaaagc tcgaggtttg atgattatct tcgaagagaa
     1021 taccggttaa agggaaggta ttttgcagaa agaaccacta tttcaaatgg aaagataggt
     1081 tatctttcat ctgactattt tgaaggcaag caaattccgg ttcgctctag agcttttgtt
     1141 gacgaagcag gccatattaa atggccaaat gccgatggct ttatggtgga taatttaggt
     1201 aatcctataa cggagcaggt cactctcaaa gcaggtcaaa tcattgatcg atatggatca
     1261 agtagtggtc gatttaccag tccgatagaa aatggggtga cattaccatt taataaacgt
     1321 ggattaccct acccagaagg atatcaagac tattataagt acgaattagt aatggatttg
     1381 acgaagaaaa atattgttaa tgcgtattat caatctgaag agattataag aaaacaaata
     1441 tctgtagaaa tgaaaaaatg gaatctttcc tttgatgatt tagctaatat tcagaagggt
     1501 gagattacca aagtatttgg gcaaggtgga ggaattcaga ttaaatttcc gacaggtgtt
     1561 ggtatttaca agaaaatggg tttattaaag gagattaact agatggataa tacaaatata
     1621 ttgaattgga aaaaagatat tgaagaagca attaaaaatc gaggttttga gagtttacat
     1681 tatgttttat ttgatgaaga aaagcgactt ccttgggcat ttcatcttta tcaaaaaaat
     1741 ggaaaattct atgttgaagg aagagatgag cgatcatata tcattggtca tagcagggaa
     1801 tatcgtaaat ttgatgatgc caagcatgaa ttgcttaaaa aattagaatt agttatagaa
     1861 tctaatcggt taaaaaagca gttaggtgaa cctacagaat atccctcacc actatggaat
     1921 gaatgagttt catgtattgt atgccatggc accaagcttt taggaggcag cgagcaagac
     1981 gcccaaagag caacattagt tgggaatatc ctaggaggac ttgccgcctc aagcgccgct
     2041 agaaggttca gcttgaatga gccaatagca actagggtga cgaaaccgac ccacaaccgc
     2101 cagcagcttt tgaagaacct tgagaacagc agactggcaa gagaaagctc aaggtttaag
     2161 aattatgtag caagagaaaa attcatgaca acccttgcag gcatgagtcc tgaggatagt
     2221 cagcgctata ttcaatggca caaatacgca aaggctggac ttagtccgtc agatcgagta
     2281 aggattctag aaatatctga gaaggcaccg aagatagagt atcttccggg aaaaacatca
     2341 gatagtatat tggcaatatc caagggtgat cgtccaaatg tggagaaagt ctacagtcca
     2401 gattatattg gatttcatag aaaacaattt gataacggtg caactagatt tcagaaattt
     2461 aagcccaatg tagattacca agacggttta gttggtgacg atttaggcaa tagtttttgg
     2521 ttaagtacca aggacgcgga tattatccag gagataggaa agggaaataa ccgtctttat
     2581 gagacactct taggctttga tgaagggtat ttagaagatg gtcccctcta tcgcttagat
     2641 gtttcaccag aagttgtttc acaaaaaggt gtttcaatac caagtggtaa tgaaaaaggg
     2701 gcaaatagct ggtggcgtcc tggaggtcgt acttatccgg ggaatatacc agagggagtt
     2761 atgcaaggta tcagtacaaa gaaaggagat cacacatggc acgcagtcaa ttagagtggg
     2821 aagatgttag tcaatatgag gaggtaaagg gctatggtca aagggtgtgg aagcatcaag
     2881 ggaaatatta ctttgttgcc gaagaaggtg gcattgctgt tcaacgagta gtatatgagt
     2941 taccgtatga cttatttgaa ttgttggaaa gtggagaacg tagtcttgga gatgttcatt
     3001 caaagctaca agatggtaat tggccaccaa cagaagagga aaagaagcaa agtcatagaa
     3061 aatttgttat tgacacacca actgcgctga ttgcagaccc tactagtgtg tctctgttct
     3121 cagaagaaga attatcaaaa ttagtgccaa tcgctgaaca acagtggata gattggaagg
     3181 gaaagctgcc agatgattat gtcagtcctt tgaaataatg tttaagatag cggagccgag
     3241 attagctctg ctattttaaa gcatgttctt aataattagc ctgcgacagc ttatcaggga
     3301 gtagctcgtc accttgaagc caatgccaag cgtctccaag cgccgccaga aggttcagct
     3361 tgaatgagcc gatagcagct aaagtgacga aatcagcgaa aataaccctt tctgaaaagg
     3421 tactagacac aaaggttcgg tttgatgagt ctcgcattgt ggcttacgca gaaagtatga
     3481 gtaagaacta tacagaagct gacgtggcca aattaaccga gctgaccacc cacaatgcaa
     3541 aaaccaaaac agctttgctg ggatattacg aagcaaacag cgttacttcg tatgaacaaa
     3601 ttgcacatca aaataagtta acttactttg atgccggaag tgatggttgg aatgcgatgt
     3661 cgagagtgga ttctaagcta gctcaaaggg ttaatcgtga atttttgata aaacaaattg
     3721 agaaaagaaa aacatttata ttaacgtcta atccatatac tgctcaatca atcgcagatg
     3781 ttagtggtat cgggaagtct tatgctaaag aaattcagat tttagcagaa aatggatata
     3841 atattgaaaa atttgaaagg ttttggaggg catataaatg agtgaagaac agtatttacc
     3901 agtaaaggaa agcttaggat atcgtaactt aaaaatagct ttaatgaatg ttttttcaat
     3961 agatttggat aagtttacaa ttattgaagg agaatttgaa aattttggtt ttcatttaaa
     4021 ttataacaat aaagaaatca taatctggat tacatcaact ggtaagaata gacaatttga
     4081 atatggagaa ggaggacaat tgatgatttc acttcctaat ccaaagtatc ctgatagatc
     4141 ctttcttgat agggtaacct tagaaagtct tttaacagac accgaaaaaa tagaagcagt
     4201 tgactatgct tttggaagat acgagcatcg tctcgaaata gcgttggcca ttctaaaaga
     4261 ttatttagat tcagacgaag caaaggtttt attgaaaaat gagtgagcaa tatttatcaa
     4321 taaaagaaag cttaggttat aagaacgtta aacaggcttt atggactatt ttttcagcca
     4381 accttgatga aatttctata catgaaggag aagatgagaa ttttaacttt gtctttacat
     4441 ataaaaattg tgaaatgatg atgggaattt atgatactgg taagaatatt caattccaag
     4501 ctggagaagg tggtttattc agtgtaagtt tacctaatcc taaatatccg gagcagtcat
     4561 ttcaaaaaat tgtatcactt tcttatttaa tttctgataa aaatgtaagt gaaaatataa
     4621 gatggtgctt aggactggat ctgaaatctg ttgaatatgt tatgcgtgtt ttgaaggatt
     4681 atctggatca aaaatgtgaa gaggaacaat aattctaatc acttctggag ggcatataga
     4741 tgagtgaaga acagtattta ccaatacctt cgaagagaat accagttaaa gggaaggtat
     4801 tttgcagaaa gaatcaccat gccagatgga aaatatgctt atctgtccaa tgacattgat
     4861 aaagctaccg gaacaccaat tcctgtccga tatagaaatt accttaaggc tgatggttct
     4921 attaattggc caaactataa tggctttagt cttgatgtaa agggaaggcc tatcatgact
     4981 ccagctttcc taaaaacagg tgatttactt gatagatatg gagaatctgg aggaacattc
     5041 acaagtccaa tcgttgaccg taaggttata ccatttaaca agcgaggctt accataccca
     5101 gaggactatc aaaattatca tcaatataag gttcttaagg atattaatat ggaaaatgtt
     5161 gaaaagggtt accataattt atctgatagt agaaaaaaag agttaaatct attaatgaat
     5221 agatttgatt tttcactggt agacatagca actccacaaa aaggaatgat tgatcttgtc
     5281 tttggctctg gtggaggtat ccaaataaag ttaggaactt ctgtaagttg gtatgaaaaa
     5341 ttgggtttaa ttaaggagat aaagtagatg aaaaatttag atcatcaaaa ggcagaacta
     5401 ttagaagcag tccatcaatt aggttatgat agtctaaggt attccatttt ttctaaagag
     5461 agaccaggag aatgggaaac tgtcattgaa tatgataata gtcaaggctt atatgttgtg
     5521 tatgcaacta tggatagagc tagttataat aagaaattaa catttgaaac atttcaagag
     5581 gctaaagaaa aatttcttga aaaacttcgg ttagatatcc aaatcaacag gtactatgtg
     5641 gaagagggca tgcctgtaaa ttacgattct cctttgtggt caaaaaatta atacaagtaa
     5701 aggagaatat acatggcatg tagtcaatta gagtgggaag ataaatgaaa taatggtcct
     5761 aggaaatgtc ccgactggaa actatcttat gaactctttt atggaaaagt gttgcactta
     5821 atttgaattt tgtcatataa aaaagcccta taatctccat ggtggactta cccactacag
     5881 aaatgataga gctaaaaatc tccatttggg gatttttttg taaccaaatg aagcagtcgt
     5941 tcgttatata ggtgaagaag ggaggggaga attatcaggc tagatgctta tgaaagagag
     6001 ctagtggctt attctaagga aattattgcc tacctagtga gatcaggtgt tgctaaggag
     6061 ctagcgcgtg atattagtca agacgttttg ttaaaaatgc ttgagagtga ccttgctctg
     6121 cctcctgaaa aaatacgtgc ctggatgtat cgggttgctg ttagaaaata cattgaccga
     6181 tataggcggg ataaggctta cttggatatt ctccaaaggg atttttttca tcaagaaagg
     6241 gttgttgaat ttgaccaccc caattatgag ccgctttata cagcagtcaa tgaattgcca
     6301 gaaaaatacc gctgggtctt gtcgttttat tactttcagg acctatcagt caaggaaatg
     6361 gcgtctctgc tccattggtc agttagcagc gtcaaggtca acttgatgcg gggaagacga
     6421 tgccttaaag aaaaactaaa gaaagcaggt tatacctatg acgatttcaa ctgattttga
     6481 agccattgct aagcgccata aaaggaggct gacccttaaa tatgtagtgc tgagtgctgg
     6541 cttagcctta gtagctcttg tactgggcta tatgggatta aatcgattga caagcatgaa
     6601 cggtcagtat ttaatggctt attacaacaa tcgtatacaa attgcttatc ccaatattga
     6661 tgttaatagc ttcttttaca atgccaattc gcagtttact ggtgagcttc attctgagcg
     6721 gaccaaggat attgctggga tttcggtacc gtttgagccc tatagagctc cttattcctt
     6781 gcctttaccc agagagagat ggactatacc aatgaatacc ttgtttcagg tgatgatgga
     6841 cggtcaacct acacaagagg tacacattat aaaatgcctc gcttcttcaa cactaaggcc
     6901 aagatcacag aaagcaacta tgacaagcca acgcaggacc tagactttat tgctgacatg
     6961 tcaggacagg cgattgaggt agccattacc tttgataagc cttatttatt atcggacata
     7021 gtcaagctgg ttccagacca gctaaagctg aattggatct ggattggcac agaaagcagc
     7081 tatgacacct cagggctttt ccctgctaat ttatatggct ttaagccaaa ctggaaggct
     7141 aatatgacgt acaaggagca aaagcagtta gataaaaaaa taaacgatat cctaaaaaag
     7201 gacagcgagg ctgatttgtc taagcttaat gctgcttacg ataagccagt cagtccaacg
     7261 gtggctctgc aaaattccta tgataccttc aggcactatc tacaagaggc agctgacaat
     7321 cattggatta atagtaccta tggcggcgct aatggatctc atttaagtga gcaggaggat
     7381 gtggccttat ttctaaaaaa caatcgcaat gtcaaaacag ctaagtttgc tggcattatt
     7441 ttaaccggca aggctgagca gtttgcctcc ttaaaaacag ctgattggat ttatgcctca
     7501 aatattggtc agtctgttgc cattcagccc tatcatcagc taaccaagta aataaaaagc
     7561 ttgtgctgct aatcaagcgc atcaggcaaa ggataaaaag cctaaaagag attagattaa
     7621 gtaaatcgat gcttaaaaaa gctccagctt aggtcaaaag acgtcaaaag gctcttggag
     7681 gtcagtgttt gatcactgct tctggggctt tttgctttgc tgcaatcaaa aaagcttgaa
     7741 gcagctctct caattgagca tgtccttcaa gctgagactc ttatatttta tagtatttgt
     7801 aagtatagtt ttagctagcc ttcttttaag cccaagggct tagcttactg tttagtatct
     7861 ttttctaaat tattgataat aactggataa tccttcaatg cagacttcat gtcatttaga
     7921 gtgctttgat atgctgtttg gtctgaggct accaatgcta gcttgtcatt ccatgcttta
     7981 tagtttaatg gctctgcctt tagagcagca tctaaatgat taagcttagt ctccttgtca
     8041 gtagctgctt cagccttata tcgttcatat tctgaggcat tataagcgtc tatattaaga
     8101 gagtagacgt tatgaatttg gacataagga agtgttgtgt tgtagttacc acagcctgtc
     8161 cagcctgaga catcatagcc gagctgatag gtatggtcag catttaagta gatataagca
     8221 cagtgacctg gttgtccaat aggaaaggct ggtacaccat aagcctgtgc tagcacacta
     8281 cttaatttag acatagcacc gcagacacca ccatatttga tgacttcctt gatggttgga
     8341 tttggtccgt aaaagccaga gctttggacg ctcacacctg tttctgggtt ggtcatgaca
     8401 tagctgatca gtgaatagcc cttagtaata tcattacggt taatcatagc aggcttattg
     8461 gtttcaacgt attgtcttaa ccatttcatg tcctcatcag taattttagc attgacgaca
     8521 tttcggattt gctcaacagt taagctgtaa aaatcttcaa ataggatatt gccctgctca
     8581 gcctctgcaa aggttgcaaa tctttcaagt ggatcaatct tgcggctttc attgtaccaa
     8641 gcacctacag gcttgttaaa ttccaaggca accgcaatgg ccattttgag ctgaatacct
     8701 tgatgtgagg tttcgtattt atcccaaatc ttaaaccaca attccaatgc ttctagctca
     8761 ttggtgaggt tataggtgtt tttgaattgg tatgatgaca tgccaccctg tgctgcagaa
     8821 tgggcatagc ctgcaccaag atataattgc attgcttcat tatctttgag caaccaatca
     8881 ataaaggctt tatgcttgtc gtcttgcttc ttgaagtcct cgattttttc cttggttagt
     8941 cttttttcaa cggcttgtac gagtgtatta gtagctttag cctctagtgc aaatacagaa
     9001 gccaaaccac ccttggtgat tcgaatctct gccttatttt tagggaggct aagagaaaca
     9061 gccttgtttt cttcatcata ggctttgact ctagtatggt gctcactacc agttaggcgg
     9121 atcttgtagc ccaccttgaa gggaatagtc tctgttttgg ctgttagagc ttggtttcca
     9181 ataaagtctt gtgtgtagac aaccttgtct tttaggtcta agacctcaag cttttcgtaa
     9241 gtcccactga agtaaacatg tggcttagcc tttttggttt tgagagttaa ggtagaggca
     9301 ttgtagtcaa cctttaaggt tgcgtattct gcattgccta agccaaggaa gcgcagcgtt
     9361 ctattactat catcaatacg ctcaagctgc ccgtttctca ccacataagt gtaagggttg
     9421 gtattgtttt gctttagagc gtcattgtgg ttagtgtaga agcggttagg ctcctgctta
     9481 gtgatgacta ggtaatagcc ttccttgaga gtaaggcttt ctgttttagc tgtttgggaa
     9541 acattaccca cgtattcctt agcataaacg gtttcttttt tctcattgag aatggttagg
     9601 gtagcgtaat tgttagcgat gtaagagtga ggctgtcctt ttttagtgac taagcttgca
     9661 gtgtaactgc cgtcagcata gaagtagagc tgagcaaata taccatttcc tagcccttgt
     9721 agagtaaatt gctgtagcag gctagctgcc ttatcaagta aacttaggat ttgctctttt
     9781 tcaggctctg ttgagtcagt cgcctttttc ctaagagcat ctattttttc ttgtgtgaca
     9841 ccacttgcta gcttacttgt agactcatct gtaaatagag tcagtacctc agactcaagc
     9901 tctgagcctg ttttagacct cattagctct agtgagtggt caagaagctt taaggttgct
     9961 tgatttttag agagtgttaa tggcgcttct accgcataat catcgtagaa tttcactctg
    10021 gtatggtgct cactacctgt caagcggatc ttgtagccta ctttaaaagg aatagtctct
    10081 gttttagctt cgaggacttg agttccaata aagtcctttg tgtagattac ttgattttct
    10141 gtatccagca cctcaagctt ttcataagat ccactgaagt aaacatgtgg cttggtctgc
    10201 ttggttttga gggttagggt agaggcattg taatcaaccc ttaaggttgc atactctgca
    10261 ttgcctaagc caaggaagcg cagcgttcta ttactatcat caatacgctc aagctgccca
    10321 tctctcacca cataagtata agggttggta ttgttttgct ttagagcgtc attatggtta
    10381 gtgtagaagc ggttaggctc ctgtttattg atgatgaggt aatagccttc ttttagctca
    10441 agctcttctg tttgtgctac ctgagaaaca ttgccggcgt attcttttga atagacggtt
    10501 tccttcttgt tattaagaat ggttatcgta gcgtaattag tagagaaata agagtgaggc
    10561 tggccccttt tagtgaccaa acttgcagtg tagctgccat cagcatagaa gtaaagttga
    10621 gcaaagacac cattgcctaa cccttgtagg gtaaactgct gtaataggct agctgcctta
    10681 tctagtagac ctaggatttg ctctttttca ggctctgttg agtcagtcgc cttttgcttt
    10741 aaggtatcta ttttttcttg tgtgacacca cttgccagct tactgcagga gttatctgta
    10801 aataaggctt gggtatcagt catcagttgt gatagcttag cctcggcaga aggagcagct
    10861 gtatcacctg cattaactgt agcggctatt ccatcagaag tatcagtagt tgcataaaca
    10921 attgctggag agagctgatg taatgttaat attccaacac atgctagtgc tattattttc
    10981 tttagtttca tcgttataaa gtccttttac aataaaataa agtgattcaa aactctggga
    11041 aaagaatagc tagccttaaa actatactcg caaatactat aaaatagaaa gactatttac
    11101 cctccttagc tcttgatgct gtggtgatga tattgttacg gtgctaaaaa tcctatccct
    11161 cctttttgac tattttgtct ctcttattcc ataatattaa aaaatcagaa tatgtcaata
    11221 tatattttct ttaatcctag aaatgataaa taggtttgga aaattcttaa tcattgatag
    11281 c
//
LOCUS       DARYNN010000059        11060 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.059, whole genome shotgun sequence.
ACCESSION   DARYNN010000059 DARYNN010000000
VERSION     DARYNN010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11060)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11060)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11060
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.059"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            67..260
                     /gene="ssrS"
                     /locus_tag="TVB59_001705"
     ncRNA           67..260
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="TVB59_001705"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            262..334
                     /locus_tag="TVB59_001706"
     tRNA            262..334
                     /locus_tag="TVB59_001706"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:295..297,aa:Lys,seq:ctt)
     gene            560..1054
                     /locus_tag="TVB59_001707"
                     /pseudo
     CDS             560..1054
                     /locus_tag="TVB59_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623587.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(1418..2128)
                     /gene="speh"
                     /locus_tag="TVB59_001708"
     CDS             complement(1418..2128)
                     /gene="speh"
                     /locus_tag="TVB59_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeH"
                     /protein_id="HEL1010572.1"
                     /translation="MRYNCRYSHIDKKIYSMIICLSFLLYSNVVQANSYNTTNRHNLE
                     SLYKHDSNLIEADSIKNSPDIVTSHMLKYSVKDKNLSVFFEKDWISQEFKDKEVDIYA
                     LSAQEACECPGKRYEAFGGITLTNSEKKEIKVPINVWDKSKQHPPMFITVNKPKVTAQ
                     EVDIKVRKLLIKKYDIYNNREQKYSKGTVTLDLNSGKDIVFDLYYFGNGDFNSMLKIY
                     SNNERIDSTQFHVDVSIS"
     gene            complement(2154..2831)
                     /gene="spei"
                     /locus_tag="TVB59_001709"
     CDS             complement(2154..2831)
                     /gene="spei"
                     /locus_tag="TVB59_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_047373492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeI"
                     /protein_id="HEL1010573.1"
                     /translation="MSSVGVINLRNLYSTYDPTEVKGKINEGPPFSGSLFYKNIPYGN
                     SSIELKVELNSVEKAKFFSGKRVDIFTLEYSPPCNSNIKKNSYGGITLSDGNRIDKKN
                     IPVNIFIDGVQQKYSYTDISTVSTDKKEVTIQELDVKSRYYLQKHFNIYGYGDVKDFG
                     RSSRFQSGFEEGNIIFHLNSGERISYNLFDTGHGDRESMLKKYSDNKTAYSDQLHIDI
                     YLVKFNK"
     gene            complement(3105..4439)
                     /locus_tag="TVB59_001710"
     CDS             complement(3105..4439)
                     /locus_tag="TVB59_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysin"
                     /protein_id="HEL1010574.1"
                     /translation="MATYQEYKSRSNGNAYDIDGSLGAQCWDGYADYCKYLGLPYANC
                     TNTGYARDIWEQRHKNGILNYFDEVETMQAGDVAIFMVVAGVTPYSHVAIFDSDAGSG
                     YGWFLGQNQGGANGAYNLVKIPYSTTYPTAFRPKVFKNAVTVIGNIGLNKGDYFIDVS
                     AYQQADLTATCQQAGTTKTIIKVSESLAWLSDRHQQQANTSDPIGYYHFGRFGGDSNL
                     AQREADLFLSNLPTKKVSYLVIDYEDSASADKEANTNAVIAFMDKIANAGYKPVYYSY
                     KPFTLNNIDYQQIIAKYPNSIWIAGYPDYEVRTEPLWEFFPSMDGVRWWQFTSVGVAG
                     GLDKNIVLLADDSSKVDIPKIDKPQSQLTFNQKLDTNTKLDNSNVPYYEATLSTDYYV
                     ESKPNASSADKEFIKAGTRVRVYEKVNGWSRINASQSDQWVEDKYLSNATQV"
     gene            complement(4556..4783)
                     /locus_tag="TVB59_001711"
     CDS             complement(4556..4783)
                     /locus_tag="TVB59_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEL1010575.1"
                     /translation="MINLKLRLQNKVTLMAILGAIFLLAQQLGIKLPSNIADIANTAV
                     TLLVLLGVVTDPTTKGLSDSEQALTYHEPKQ"
     gene            complement(4780..5052)
                     /locus_tag="TVB59_001712"
     CDS             complement(4780..5052)
                     /locus_tag="TVB59_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010576.1"
                     /translation="MATELIFGLGGFILAIVTTYNIFNAKSIKHATDITLLQSEVEHL
                     KIVTRQNARRLEEHDEQNKTLITMTEQIKNLNREVRELKDIMRGEA"
     gene            complement(5064..5675)
                     /locus_tag="TVB59_001713"
     CDS             complement(5064..5675)
                     /locus_tag="TVB59_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1366 domain-containing protein"
                     /protein_id="HEL1010577.1"
                     /translation="MRNWKVTGKYPQFDSTGAVASTHIIITAEDGSVISQPIKQGLTS
                     TNDTEIIKATLEEFKKSEYVEIAMGEAVQKVDDLEKISQETAKTAKTAQTAAGLAKVS
                     AERTQRMINLQTIHVLTSGGKVEPDIYKGMLELIEPAKQGEYQAYDVFTVVDESHEDQ
                     AGEGNLVFVHVNEPFTYDKQTLKELEEEDKVTVIKYADLVKQD"
     gene            complement(5672..6109)
                     /locus_tag="TVB59_001714"
     CDS             complement(5672..6109)
                     /locus_tag="TVB59_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1617 family protein"
                     /protein_id="HEL1010578.1"
                     /translation="MDLTLKNKDLNTLYSVLDKIKVTNMRANRGRAKLLAKVVDKFKE
                     YAKDEGDLIDLYAQKDKDGKFVIDEHKNIKLADPAKLDEFNGLLNELADEEIVIKGGE
                     YSKRFIDFLNFLEECEDEFTSSEIILIDNILEQFEESKKGEKP"
     gene            complement(6121..8007)
                     /locus_tag="TVB59_001715"
     CDS             complement(6121..8007)
                     /locus_tag="TVB59_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gp58-like family protein"
                     /protein_id="HEL1010579.1"
                     /translation="MSRDPTLILDESNLVIGKDGRVHYTFTAEDDNPKVRLASKCLGT
                     AHFNQLMIERGDQATSYVAPVVVEGTGNPTGLFKDLKEISLELTDTANSQLWSKIKLT
                     NRGMLQEYYDGKIKTEIVNSARGVATRISEDTDKKLALINDTIDGIRREYRDADRKLS
                     ASYQAGIEGLKATMANDKIGLQAEIKASAQGLSQKYDDELRKLSAKITTTSSGTTEAY
                     ESKLAGLRAEFTRSNQGTRTELESQISGLRAVQQSTASQISQEIRDREGAVSRVQQSL
                     ESYQRRMQDAEENYSSLTHTVRGLQSDVGSPTGKIQSRLTQLAGQIEQRVTRDGVMSI
                     ISGAGDSIKLAIQKAGGINAKMSGNEIISAINLNSYGVTIAGKHIALDGNTTVNGTFT
                     TKIAEAIKIRADQIIAGTIDAARIRVINLNASSIVGLDANFIKAKIGYAITDLLEGKV
                     IKARNGAMLIDLNTAKMDFNSDATINFNSKNNALVRKDGTHTAFVHFSNATPKGYTGS
                     ALYASIGITSSGDGVNSASSGRFAGLRSFRYATGYNHTAAVDQTELYGDNVLIADDFS
                     INRGFKFRPDKMQKMLDMNDLYAAVVALGRCWGHLANVGWNTAHSNFTSAVTNELNNH
                     INKI"
     gene            complement(8022..9140)
                     /locus_tag="TVB59_001716"
     CDS             complement(8022..9140)
                     /locus_tag="TVB59_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_192934711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronoglucosaminidase"
                     /protein_id="HEL1010580.1"
                     /translation="MSKEVASARIQHRGMTKQEWESSSDILMEREIGIDMTTGYPKVG
                     DGKNKFKDLKDLRGPMGPQGPSGERGLTGPIGPRGPAGKPGTTDYNQLQNKPNLDAFA
                     QKKETNSKITKLESSKADKSAVYSKAESKIELDKKLSLTGGIVTGQLQFKPNKSGIKP
                     SSSVGGAINIDMSKSEGAGVVVYSNNDTSDGPLMSLRTGKETFNKSALFVDYKGTTNA
                     VNIVMRQPTTPNFSSALNITSDNENGSAMQLRGSEKALGTLKITHENPNVEAKYDENA
                     TALSIDIVKKQKGGKGTAAQGIYINSTSGTTGKLLRIRNLSDDKFYVKSDGGFYAKET
                     SQIDGNLKLKDPTANDHAATKAYVDKAISELKKLILKK"
     gene            complement(9140..>11060)
                     /locus_tag="TVB59_001717"
     CDS             complement(9140..>11060)
                     /locus_tag="TVB59_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1010581.1"
                     /translation="NAVNGERSVSGEIYTNSDVLNNIDRGWRLRFEDEYYVVIYAKPV
                     DVGQKTQVSFDAIHQFFWDFSKSSIYEGLGDGSHTIDTYLETVFKGSGYRYKLEVGVN
                     AFRKQSFNYKSRLDLFNEIIKATGLEFSVSGKVVRLLKNIGTDLSTVVRKNFNMNDLT
                     IEKNIDSFITYQKGFGAWTDPEDHSKGRLEAEYESPLAKEYGRLEGAPLTDERFTVAD
                     NLKEALKSNVENSYKISVKIDMEDLTRAGYRCERPVAGDYIMAINETLGFQERIRIVS
                     FTSYYDATGALVKHEVTCNDIGSVKKQSVGSLSINSRINQIDADIASAIEVATQALVS
                     ADGKNTVYGGTEMPKDEPKGTLKKGDILFLKVGDTTRMYFWNGAEWEEPEVVNDPERW
                     REDLEKQISEAIEKAKKAQEEINQRTDKELEEFRAALKNLALPEEAIKKITEAIKVDD
                     IPSIKQSFDDLKNRVSETSEESRLTAEILGNNGKTRYNKNLLVGEPNRVKKIDEDFIE
                     VEANDGGFKRGETYTISFSQTCEPLKKVAITLIQANNKGVKLVLTPTKAKMEPETFTL
                     IKDTEVINVYPLSYSVTLSGDWYKSKQVDLNASEVRNMALGMSYRDVVDGNNADLILD
                     WAENPDIIFDGNGGI"
BASE COUNT         3066 a         2344 c         1899 g         3751 t
ORIGIN      
        1 atacgatctt tttttcattt tagggcttga aaaattttca aaaagtggta tcataagagc
       61 atagagttat tgctgtggca tacgaattca catctaagtg ttgaccgact atttttttgt
      121 attttaggga aacaaagtct atctctagta tgcaagccgt ttcacgtgga agcaatctga
      181 agagaagtat gttgcccacc tgcttatatc gtgcgggttc aatacaaaac gtgaatcacc
      241 ggtgccaata cagctttcct tacctcctta gctcagttgg tagagcagta gactcttaat
      301 ctatgggtca caggttcgag ccctgtaggg ggtatagtgt aaaaacgaca aaaagccttt
      361 attgcagggc ttttttgctt gcctaaagag ggtttgtccc accatttgtc cccgaaacaa
      421 ttttttatga tatgatgtta aataaagaat ttattacttt ttaaaaagag agctaacaca
      481 tgacaataat ataattaaca caaggtgata caatcggagt attttcacct ccatcacctg
      541 cgacggaatt tggagaaaaa tggctttttt taattattcg caggctttaa cagttggaca
      601 aatagatatt aaaaatgctc gcttaaaagc tggaaaaaca caaaaagaac tcgctaaatt
      661 aataggagtt actaagcaaa caattattaa tgacgaaaag gggactactg aaccttcatg
      721 ggataggctt caagagattg ctacagcctt aaatgttgat attgatacct tatttcccta
      781 caatatgtta ggagaaaaaa gagactttaa gtggatggag cacctagaga gactcgaaaa
      841 taattggctt tatagccgta tggccgagga agaagtatta cttcaaaaaa ttctagattt
      901 tgcaatattt caaaataaat tagataaaaa cactctaaca actaaagaac ttaatcttga
      961 agacaacaac actatgtcca aagaagataa aatttcactc atcatattga aatatgaaaa
     1021 agaaattcaa gaaaaaactc aaaaacttct tgagtttatt cccgaaaaaa cacaaggaac
     1081 aataatggtt acaaagtcga taataaaagc atttgttagt attaaaccgg tattgtatcg
     1141 acacaagaaa cgacaaaagt tctaaactta tgccccaatt ttgccccaat ggttctttct
     1201 tgattctttg gtgaactaaa attattcaga ctcagaaagt tctgccataa catcggatat
     1261 ccgctcgatt gtcacaacct cccaatctct tatctcctca tatattttat attaaaatat
     1321 caataaatat tagcataatt ttaaaacact aaaaatatat cttggtaatt tttactttat
     1381 ttatctattt ttaataaaca gcttcttaaa aatataatta gctgattgac acatctacat
     1441 gaaattgagt tgagtctatt ctctcgttat tggaatatat ttttagcatg ctattaaagt
     1501 ctccattgcc aaaataatac aaatcaaaaa caatatcttt acctgaattt aaatctaagg
     1561 taacagttcc tttagagtat ttttgttccc ggttattata gatatcgtat ttcttaatca
     1621 ataactttct aacttttata tccacttcct gagcggttac tttcggttta ttgactgtaa
     1681 taaacatagg cggatgttgt ttacttttat cccacacgtt tataggaact ttaatttctt
     1741 ttttttctga attagttaat gtaattccac caaacgcttc ataccttttt cctggacatt
     1801 cacaagcctc ttgtgcagat agagcataaa tatctacttc tttatctttg aattcctgtg
     1861 atatccaatc tttctcaaaa aaaactgaca aatttttatc cttgacacta tatttcaaca
     1921 tatggcttgt tacaatatct ggagaatttt ttatactatc ggcttcaatt aagttagaat
     1981 catgcttata aagcgattct agattatgtc tattggttgt attataagaa tttgcttgaa
     2041 caacattgga atataaaaga aatgacaaac atataatcat gctgtagatt ttcttatcaa
     2101 tatgtgagta gcgacaatta tatctcattt tttctcctta agaagtgaga gttttattta
     2161 ttaaatttaa ctaagtatat atcaatatga agttgatcag aataagcggt cttattatca
     2221 ctgtattttt ttagcatact ctctctgtca ccatgtcctg tatcaaaaag attataagaa
     2281 attctctctc cactattcaa atgaaaaata atatttcctt cctcaaagcc agattgaaat
     2341 ctagaggagc ggccaaaatc tttaacatca ccgtatccgt atatattaaa atgtttttga
     2401 agataatatc ttgatttcac atcaagttcc tgaatagtaa cctctttctt atcagtactc
     2461 actgtactta tatctgtata gctatatttt tgttgaacgc cgtctatgaa aatattaaca
     2521 ggtatatttt ttttatcaat tctattaccg tcgcttaaag taatacctcc atatgaattc
     2581 ttttttatat tagagttaca gggaggagaa tactccaaag taaatatatc caccctttta
     2641 ccagaaaaaa atttagcttt ttctacgcta ttaagttcta cttttaattc aatcgaacta
     2701 ttgccataag gaatattttt gtagaacaaa ctacctgaaa atggcggacc ttcatttatt
     2761 tttcctttta cttctgttgg atcatatgta gagtataaat tccttaaatt aataactccc
     2821 acactactca tctcatacgc gtaacacgtt ggaattatag ctgatataaa tacccacaat
     2881 agaaaagatg aagttaaaaa ctttttaaaa ttaacattta caatttttct cacttataag
     2941 tgtaccctat tcttctttaa taataagaaa tcacaaaata ttttagcaca aaaaagaaaa
     3001 aaatcaacga aaatgcttaa ataacaatta aaatctttat aacaaaaaca gcccccgcaa
     3061 aagcgagggc atttgtctta tctaaaggag ctttacctcc tattttatac ttgtgttgca
     3121 ttagataaat acttatcttc gacccactgg tcagactgag aagcgttaat acgtgaccat
     3181 ccattcactt tttcatagac tcttacacga gttcctgcct tgataaattc tttatcagcg
     3241 ctacttgcgt ttggcttaga ctctacataa tagtctgtgc taagggttgc ttcgtagtaa
     3301 ggtacattcg agttgtctaa tttagtgtta gtatctagct tttgattaaa agtaagctgg
     3361 ctttgtggtt tgtcaatctt aggtatatcc actttgctac tatcatctgc taataataca
     3421 atatttttat ctaaaccacc tgctactcct acacttgtga actgccacca gcgcacacca
     3481 tccattgaag ggaagaactc ccaaagtggc tctgttcgta cttcgtagtc tggataacca
     3541 gctatccaaa tgctgtttgg gtacttagcg ataatttgct gataatcaat attattaagc
     3601 gtaaatggtt tatagctgta ataaacaggc ttatatccag cgtttgcaat tttatccata
     3661 aacgcaataa ctgcattagt gttagcttct ttgtcggcac ttgcagagtc ttcataatca
     3721 atgactaagt aagagacttt tttggttggt aaattggaca gaaataaatc tgcttctcgt
     3781 tgcgctaagt tgctatctcc tccaaatcgt ccaaagtgat aataaccaat agggtcacta
     3841 gtattagctt gttgctgatg cctatcagac agccaagcga gtgactcgga tactttgata
     3901 atcgttttag tagtgccagc ttgctgacaa gtagcggtta agtctgcttg ttgataagct
     3961 gatacatcaa taaaataatc gcctttattt agtcctatat tacctataac agtaactgca
     4021 tttttaaaaa cttttggtct aaatgcagta ggataagtcg ttgaatatgg tatttttact
     4081 aaattatatg ctccgtttgc tccaccctgg ttttgaccta aaaaccatcc gtatccacta
     4141 cctgcatcac tatcaaaaat agccacatgg ctatacggtg taacacctgc aactaccata
     4201 aaaattgcga catctccagc ttgcatagtc tctacttcgt caaagtagtt taaaatacca
     4261 tttttgtgac gttgttccca tatatccctt gcatatcctg tatttgtaca gtttgcgtat
     4321 ggcagtccta gatacttaca gtagtctgcg tagccatccc aacattgcgc accaagcgat
     4381 ccatcaatat cgtaagcatt gccatttgaa cgacttttat attcctgata tgtagccatt
     4441 tatccctcct tatctaaaaa tgggcttaaa atcaaagcaa caacagataa tggcacatac
     4501 agtattgcta ttgctataac taatgctaat cgtgtgattg cccgcatgtc ccctcctatt
     4561 gttttggttc gtggtaagtc aaagcttgct cactgtctga caggcctttc gtggttggat
     4621 ctgtgacaac accgagcaat accaaaagcg ttacagctgt gtttgcaata tccgcgatgt
     4681 ttgatggtag tttaatacct aattgctgtg ccagtaaaaa gatagctcct aaaatagcca
     4741 tcaaggttac tttgttttgt agtcgtaatt ttaaattgat catgcttcac ctctcataat
     4801 atctttaagt tctcttacct cacgattgag gtttttaatt tgctctgtca ttgtgatgag
     4861 cgttttgttt tgctcatcat gctcctcaag acgccgagca ttttggcgtg taacaatttt
     4921 taaatgctct acttcagact gcaacaaagt aatatctgtc gcatgcttga tggattttgc
     4981 attaaaaata ttgtaagtcg tgacgatagc taaaataaag ccaccaagac caaatatcaa
     5041 ctctgttgcc atagcttacc tcgctaatcc tgcttaacta agtccgcata cttaatgact
     5101 gtgactttat cctcttcctc tagctcttta agcgtctgtt tgtcataagt aaacggctcg
     5161 ttaacgtgta caaagacaag attaccttct cccgcttgat cttcgtgcga ctcatctaca
     5221 acagtaaaca cgtcataagc ctgatactcg ccttgtttag caggttcaat aagctctaac
     5281 atacctttgt agatatcggg ttcaactttc ccaccacttg tcaatacgtg gatggtttgc
     5341 aagttaatca tccgctgtgt acgctctgcg gacaccttag ctaatcctgc ggctgtttgg
     5401 gctgttttag cggtcttagc ggtttcctgt gagatttttt caaggtcgtc tactttttgc
     5461 acggcttcgc ccatagcgat ttcgacgtat tcagattttt taaattcttc caaagtagct
     5521 ttgataatct ctgtgtcatt agttgaagtt aagccctgct tgattggttg agagatgact
     5581 gagccatcct cagcagtgat aataatatgt gtgcttgcga ctgctcctgt gctgtcaaat
     5641 tgtgggtatt ttcctgtcac tttccaattt ctcatggttt ttctcctttt ttactttctt
     5701 caaattgttc caaaatgttg tcgataagaa tgatttcaga tgatgtaaat tcatcttcac
     5761 actcttctaa aaagtttaaa aagtcaataa atcgcttgga gtactcaccc cctttaatca
     5821 caatttcttc atcagctagc tcgttgagta ggccgttgaa ctcgtcgagt ttagcggggt
     5881 ctgctagctt gatgtttttg tgctcatcaa tgacaaactt gccatctttg tctttttgag
     5941 catacagatc aataaggtca ccctcatcct tggcgtactc tttgaattta tcgactactt
     6001 ttgcgagtag cttagcacgt ccgcggtttg ctcgcatgtt cgtgactttg attttgtcta
     6061 gtacactata tagtgtgttt aaatctttgt ttttaagcgt taaatccatt gtttctccta
     6121 ttaaattttg ttgatatgat tatttaactc gttagtgacc gcacttgtaa aattgctatg
     6181 agcagtattc cagccgacgt tagccaagtg cccccaacag cggcctaagg ctactacagc
     6241 cgcatacaag tcgttcatgt caagcatttt ttgcatcttg tctggtctaa atttaaatcc
     6301 tcgattgatg ctaaagtcat ctgcaatcaa gacattatca ccgtatagct cggtttggtc
     6361 gactgcagca gtatgattat atcccgtagc gtacctaaat gaccttagcc ctgcaaaacg
     6421 accggaagaa gccgagttaa caccgtcacc agatgaggtt atcccgatcg atgcatacaa
     6481 cgctgaccct gtataacctt tgggcgtcgc attactaaaa tgtacaaagg cagtatgtgt
     6541 gccatcttta cgtactaagg cattgttttt gctattaaaa ttaattgtgg catcgctatt
     6601 aaagtccatc ttagctgtat ttaagtcgat aagcatcgct ccattacgag ccttaatgac
     6661 cttaccctcg agcaaatcag tgatagcata gccaatttta gctttgataa agttagcgtc
     6721 taaaccaacg atactacttg cgttaaggtt aatcactcta atcctagcag cgtcaatcgt
     6781 gcctgcaata atctgatcag ccctaatctt gatagcctct gctatctttg tggtaaaggt
     6841 gccgttgaca gtcgtattgc catcgagagc gatgtgttta cctgcgattg ttactccgta
     6901 ggagttgagg ttaattgctg agataatctc attaccagac attttggcat taatgccgcc
     6961 agccttttgg atagctaatt taatgctgtc tccagcgcca ctaataatac tcatgacacc
     7021 atctctagta acccgctgct caatttgtcc tgctagttga gtaaggcgcg attggatttt
     7081 accagtcgga gatccaacgt cgctctgtag ccctctaacc gtatgggtca agctactata
     7141 gttttcttct gcgtcctgca tccgcctttg gtaactctcc aaactctgct gcacacgact
     7201 gacagcacct tcacggtctc taatctcttg agagatttgg ctagctgttg actgctgtac
     7261 cgctcttagc ccgctaattt gtgactcgag ctctgtcctc gtgccttgat ttgagcgagt
     7321 aaactcagca cgtaagcccg caagcttact ctcgtaggcc tctgtagtgc cgcttgaggt
     7381 tgttgtgatc ttagccgata gcttgcgcaa ctcatcatca tacttttgcg atagcccttg
     7441 tgctgaggct ttaatctcag cttgtaaacc gattttatca ttggccattg tggcttttag
     7501 cccctcgatg cctgcctgat agcttgcgga tagcttccta tcagcatctc gatactcacg
     7561 cctgatacca tcaatggtgt cattgatgag cgctagcttt ttatcagtat cctcgctgat
     7621 acgtgtagcg acacctctgg cggagttgac tatctcggtc ttgatcttac cgtcgtagta
     7681 ttcctgcaac ataccacggt tagtcagctt gatttttgac caaagctggg aattagcagt
     7741 atctgtcagc tctaggctaa tctctttgag gtctttaaat agtccagtcg gattacctgt
     7801 accctcaact actactggcg caacatagct agtagcttgg tctcctcgct caatcatgag
     7861 ctgattaaaa tgcgctgtgc ctagacactt gctagctagt ctgacttttg ggttgtcgtc
     7921 ctctgcggta aatgtgtaat gcacacgtcc atccttacca ataacgaggt ttgactcgtc
     7981 taaaataagt gttgggtctc tgctcattta tcctccttaa tctatttttt tagtatgagt
     8041 ttttttaact cagaaattgc tttatctaca taagctttgg ttgccgcatg atcattcgct
     8101 gtggggtcct tgagtttcag gttgccatca atctgcgaag tttccttggc ataaaaacca
     8161 ccgtcagact tgacgtagaa cttatcatca ctaaggtttc taatcctaag caacttccct
     8221 gtcgtgcctg atgttgagtt aatgtagatt ccttgagcag cagtaccttt tccgcctttc
     8281 tgttttttaa cgatatcaat agataacgct gtagcgtttt catcgtattt tgcctcaacg
     8341 tttgggtttt cgtgtgtgat tttgagcgtt cctagcgctt tttctgaccc tcgtagctgc
     8401 attgcactac cattttcatt gtcgctagta atattaagcg ccgatgaaaa attgggggtg
     8461 gttggctgac gcatcacaat attaacggca tttgttgttc ccttataatc gacaaaaagc
     8521 gctgatttat tgaaggtctc tttacccgtc cgcaagctca ttaacggccc atcactggta
     8581 tcattgttag aatagacaac aacaccagca ccttccgatt tagacatatc aatgttaatc
     8641 gctcctccta cggaagatga gggtttaata ccacttttat taggtttaaa ctgtagttgt
     8701 cctgtcacta tgccgcctgt caaactcaat tttttgtcta gctctatttt tgactctgct
     8761 tttgagtaaa cagcgctttt atctgctttg cttgattcta atttggtgat tttactatta
     8821 gtttcttttt tttgtgcaaa cgcatctaga tttggtttat tttggagttg attataatct
     8881 gtcgttccag gcttgccagc agggccccga ggaccaattg ggccagttag gcctctttct
     8941 cctgaaggac cttgaggtcc catagggccg cgcaagtctt ttaagtcctt gaacttattt
     9001 ttgccatcac caacttttgg gtaacccgta gtcatatcaa ttccaatttc tcgctccatt
     9061 aagatatcgg agcttgattc ccactcttgt ttggtcatgc ctctatgctg tatccttgct
     9121 gatgcaactt cttttgacat taaatacctc cgtttccgtc aaaaataata tctgggtttt
     9181 ccgcccagtc caaaattaaa tcagcattat taccatcaac cacatctcta taactcatcc
     9241 ccagagccat atttcgcacc tccgacgcat ttaaatctac ttgcttagat ttgtaccagt
     9301 caccacttaa agtgactgag tagctcaaag gatagacgtt gatgacctct gtgtccttaa
     9361 ttagagtaaa agtctcaggc tccatttttg ccttagtagg tgtcagtacc agtttaactc
     9421 ccttattatt agcttggatc agcgtgatag ccactttttt gagcggctca catgtctgac
     9481 taaagctgat tgtgtaagtc tcgccacgct tgaaaccacc atcattagct tctacctcga
     9541 taaaatcctc atcaattttt ttaacacgat taggctcacc gaccagcaaa tttttgttgt
     9601 agcgtgtctt accgttgttc cctaaaattt cggcagttaa acgagattct tcgcttgtct
     9661 cactcactct atttttgagg tcatcaaagc tttgtttaat agacgggatg tcatcaactt
     9721 ttatagcctc tgtgattttt ttaatcgctt cctctggtaa cgctaggttt ttgagggcgg
     9781 ctctaaattc ttcaagctct ttatcggtgc gttggttgat ttcttcctgt gcttttttgg
     9841 ctttttcgat cgcctcagag atttgttttt cgaggtcttc acgccatcgt tctgggtcgt
     9901 tcacaacctc aggttcttcc cactcagcac cattccagaa atacattcta gtagtatcgc
     9961 caacttttag gaataatatg tctccttttt ttaaggttcc ttttggttca tctttgggca
    10021 tttctgtgcc accgtaaaca gtatttttcc cgtcagcaga tactagtgct tgtgttgcta
    10081 cttcaattgc agaagcaata tctgcatcta tctgattgat tctactgttt atagacagac
    10141 ttcctacgct ttgttttttc acagatccga tatcattaca agtgacttca tgttttacta
    10201 aagctccagt tgcgtcgtag tagcttgtaa aagaaactat ccgtatacgc tcttgaaaac
    10261 ctaaagtctc atttatcgcc ataatgtagt caccagcaac cggcctctca catctatacc
    10321 cagctctcgt taaatcttcc atatcaattt ttactgatat cttataagaa ttttcaacat
    10381 tactttttaa agcttctttt agattatctg ccaccgtgaa gcgctcatcc gtcagaggcg
    10441 ccccttcaag tcgaccgtac tccttggcaa gaggactttc gtattccgcc tcaagtctcc
    10501 ccttagagtg gtcctctggg tcggtccatg caccaaagcc tttctgatag gtaataaagc
    10561 tatcaatatt cttttcaatg gtaaggtcat tcatgttgaa attttttcgt accactgttg
    10621 acagatcagt acctatgttt tttaatagcc gaacaacttt cccgctgact gaaaattcaa
    10681 gtccggtcgc tttaataatc tcattgaata aatctaacct ggacttataa ttaaaagatt
    10741 gttttctaaa tgcgttcaca cctacttcta gcttatagcg gtacccacta cctttaaata
    10801 ctgtctctag ataggtatca atggtatgag acccatctcc gagaccctca tagatactac
    10861 tcttgctgaa gtcccaaaaa aattggtgta tggcatcaaa cgaaacttgc gttttttgac
    10921 caacatcaac aggctttgcg taaataacaa cgtaatactc atcttcaaat ctaagtcgcc
    10981 accctctatc gatattattg aggacatcac tgtttgtata aatttccccg ctcactgagc
    11041 gctcaccatt aacagcatta
//
LOCUS       DARYNN010000060        10977 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.060, whole genome shotgun sequence.
ACCESSION   DARYNN010000060 DARYNN010000000
VERSION     DARYNN010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10977)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10977)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10977
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.060"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(32..1213)
                     /locus_tag="TVB59_001718"
     CDS             complement(32..1213)
                     /locus_tag="TVB59_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEL1010582.1"
                     /translation="MTKRLLLFVLVCLCFLGISQVHAEDVMEITRKAGYTVSEVNRPK
                     ASIVVDAKTSEILWQDNIDMPRDPASMSKMFTLYILFEELAKGKVTLDTTITATETDQ
                     AISKIYEISNNNIVAGVAYPIRDLIIMTVVPSSNAATVMIANYLSNNDASAFIDRINK
                     TAKELGMTNTHFSNASGAIAQAFQGYYLPEKYDLTASNITTARDFATLIYYFLTNYPS
                     ILDFTNQTVVRTMVGTPYEEEFHSYNHSLPDGKFGIEGVDGMKTGSSPSAAFNAVVTA
                     KRGNTRLITVVLGVGDWSDQNGEFYRHPFINALTEKAFKDSKTLTKAKRSKLKRLAAK
                     PASTAAAAKKQLPQATTDQSFLEKIEQFVDDHRPLVLICLAIFILIVLLLALMAFMMG
                     R"
     gene            complement(1297..2532)
                     /locus_tag="TVB59_001719"
     CDS             complement(1297..2532)
                     /locus_tag="TVB59_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEL1010583.1"
                     /translation="MKKLIVTLAALMCLITNTSFAENFSVNSRQAIAVEMTTGKILYA
                     KEAQQKAPIASLTKLLTVYLVLKEIKAGRLQWDSQVTLSEYALQLATDPDISNPAFEQ
                     RPYTIKELVESSLIISANSSAVALAEHIAGSEPTFVDMMKKQLEAWGIRDYLLVNASG
                     LNNSMLKGHLYPGSQPDDENQMTARDLALIAQQLIQDFPELLTISSQPQLKWGEKALP
                     SSNLLLAGREMGRAGVDGLKTGTTSQAGQTMIATAVQDNMRVISVILHADQSDTDERA
                     RFVETNRLLDYCFNSYALEKLVAQNQVLPERLIVKQAAKQRLRVKASQTLTVVRPKDQ
                     TELSYSLRIKDKALKAPIRQNKKVGTLIYQDPKLIDSGYLAAPPAVAIVSAKSIPEKG
                     KLSKLFDFFQKVIGILINP"
     gene            complement(2854..4092)
                     /locus_tag="TVB59_001720"
     CDS             complement(2854..4092)
                     /locus_tag="TVB59_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEL1010584.1"
                     /translation="MKKVLIALTILAISCLAYPAQADHYDISAKHAIAVELDSGKILY
                     EKDADKTVSVASLSKVLTAYLVYKEVQAGKLKWDSSVTISNYPYKLTTNYTISNVPLD
                     ARKYTVKELLKALIVTNANSPAIALAEKIGGTEAKFVDKMIAQLKDWGITGAKVVNAS
                     GLPNHILGEHIYPGSSLDDDNQFSAADLALVTSHLLKEFPEVLKLSSQVQAEFNHQQI
                     FSYNYMLKGMPNYRDGVDGLFVSYSEKGGSSFLATSVENNMRIITVVLNADHAQDNDT
                     AVFTATNQLLQYVLTHFKKVVVLEKGKPDQLKALPVLDSPQKKIQLVPKKKLTMIKAL
                     DDKSKTTFQVSDTKNPLVAPIQKGQTLAKATLNDHSLIGKGYLGQAPSVELVAQKKVP
                     KSFFLKVWWNHFVRYVNQYL"
     gene            4400..6376
                     /locus_tag="TVB59_001721"
     CDS             4400..6376
                     /locus_tag="TVB59_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003102586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL1010585.1"
                     /translation="MKKSKWLATLGVAALSVSILAACGNSSSKSSESKIYSYVYSSDP
                     STLDYISTSKATTNDITTNAVDGLLENDQYGNLIPSLAKDWKVSKDGLTYTYTLRDGI
                     KWYTSDGEEYADVTAEDFVAGVKHAADVNSDALYIIQDSIKGLSDYLNGKTKDFSTVG
                     VKALDKKTVQYTLNQPESFWNSKLTYSVLAPVNADFLKSKGKDFGKATDPSSILYNGP
                     FLITALTSKSSIELVKNENYWDAKNVHLDGVQLTFYDGQDQESLFRNFDDGAYSAARL
                     FPTTPSYKTVKKKYGDSITYGQQNATLYYAAFNLNRTSYNHTKKTSDSQKSDTQKAIL
                     NKDFRQAMTFAFDRIAYQAQSAGEDAANKSLRSTLVPPTFVKIGDKNFGDVVEEHLVT
                     YGSQWENVNLDDAQDGLYNPEKAKASFEKAKAALQAEGVQFPIHLDYPMDQTATVLLQ
                     QARSMKQSIEKTLGTDNVVIDIIELQKDVYENISYLAETPAQNDWDISTASGWGPDYV
                     DPSSYLDIFNPTLANSQTKSIGLEPGKDLAIASAAGLDEFTKLVTEAGKITDDLNARY
                     TLYAKAQAALTDSAIYIPTISLGGTPRVTKVVPFSGAFAWAGTKNDFYYKYVKLQDKP
                     VTAKQYDKALAEWKKEKKKSNEKYNNSLEKHIEK"
     gene            6440..7939
                     /locus_tag="TVB59_001722"
     CDS             6440..7939
                     /locus_tag="TVB59_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004184189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1010586.1"
                     /translation="MKKYIFERILRSLVSILLVTALTYTIVFTLVPKSLIFKQDPNYN
                     KMVTTPDKKTNYLNTVFENMGYISYYSSKELQNKASKLDPSVTTAPTKANEKIYQKYI
                     ASVGNGWKLGRFTESKGFYAVREIPIYERVWNFFSHLVVIDHPWKIKDPKNPNLERYV
                     RPEIDPAVGPALVGSGTKHKYLIYFNKQFPFIHQNIVTFDLGVSYPTYANIPVVQVIT
                     QGQGRTLQKEVTFPTGKTKLSSIDIYSRTYKTPSSLDSKDIANFGKGDAYTNTQNNYA
                     EPSMIANSFKIGIVGVLLSYLFGLPIGMLMAYYKNGWFDRFSTAATTFMLALPSIALI
                     YIVRFVGSYLGLPDTFPLLGAGDVRSYVLPALILGILGTPSTVVWFRRYIVDLQGSDF
                     VRFARAKGLSEFEISKNHLFKQAMVPIVNGIPQAIVGTIAGATLTETVFAFPGMGKML
                     IDSIKAANNSMVVGLVFIFAVLSILALLVGDILMTILDPRIKLSGKGGK"
     gene            7939..8865
                     /locus_tag="TVB59_001723"
     CDS             7939..8865
                     /locus_tag="TVB59_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1010587.1"
                     /translation="MAAIDKNKFTFVELDSYASEVIDAPAYSYWKSVFRQFFSRKSTI
                     LMLVILIAIILMSFIYPMFANYDFGNVSNINDFSKRYIAPNAEYWFGTDQNGQSLFDG
                     VWYGARNSILISVIATIINMIIGVIVGGIWGVSKAVDKVMIEVYNIISNLPQMLIIIV
                     LTYSIGAGFWNLIFAFCVTGWIGIAYSIRVQILRYRDLEYNLASQTLGTPTHKIVIKN
                     LLPQLVSVIVSMVSLLLPSYISSEAFLSFFGLGLPITEPSLGRLISNYSNNLTTNAYL
                     FWIPLTTLILVSLPLYIVGQNLADASDPRTHR"
     gene            8874..9944
                     /locus_tag="TVB59_001724"
     CDS             8874..9944
                     /locus_tag="TVB59_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1010588.1"
                     /translation="MTEKQEIILSAKNIVVEFDVRDRVLTAIRDVSLDLYKGEVLAVV
                     GESGSGKSVLTKTFTGMLEANGRVASGTITYAGQELTELKNHKDWEAIRGSKIATIFQ
                     DPMTSLDPIQTIGSQITEVIVKHQKKSRSEAKALAIDYMTRVGIPEPEKRFGEYPFQY
                     SGGMRQRIVIAIALACKPDILICDEPTTALDVTIQAQIIDLLKTLQKEYHFTIIFITH
                     DLGVVASIADKVAVMYAGEIIEYGKVEEIFYDPRHPYTWSLLSSLPQLADEKGVLFSI
                     PGAPPSLYKPIVGDAFAPRSQYAMAIDFEETVPRFTISDTHWAKTWLLHPDAPKVQKP
                     AVIQDLHQKILKKMSRQEEGNV"
     gene            9937..10860
                     /locus_tag="TVB59_001725"
     CDS             9937..10860
                     /locus_tag="TVB59_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1010589.1"
                     /translation="MSEKLVEVKDLEISFGEGKKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNETSSGEIRYDGKIINGKKSKSEANELIRKIQMIFQDPAASLNE
                     RATVDYIISEGLYNFNLFKTEDERKEKIKQMMSEVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMDPEFVIADEPISALDVSVRAQVLNLLKKIQSEKGLTYLFIAHDLSVVRFIS
                     DRIAVIHKGVIVEVAETEELFVNPVHPYTKSLLSAVPIPDPILERQKKLVVYHPEQHD
                     YSVDKPSMVEIKPNHFVWANQVEAERYRKEL"
BASE COUNT         3249 a         2138 c         2281 g         3309 t
ORIGIN      
        1 taccaagaag tctttttaat cagcaatgag cttaacgtcc catcataaag gccatcagag
       61 caagtagtaa aacaataagg ataaaaatgg ctaagcaaat caagacaagg ggacgatgat
      121 catcgacaaa ttgttctatt ttttcaagaa atgattgatc agttgtggct tgtggcaact
      181 gctttttggc agctgctgct gtgctggctg gtttagcagc aagcctttta agcttgcttc
      241 gttttgcttt ggtgagtgtt ttactatctt taaaggcttt ttcagtcaaa gcattaatga
      301 atgggtgacg gtaaaattct ccattttggt cagaccaatc accaactcct aggacaactg
      361 taatcagtct ggtatttcct cgttttgctg ttacgaccgc attgaaagca gcacttgggc
      421 tggatcctgt tttcatacca tcaacaccct ctattccaaa cttaccatca ggcagagagt
      481 ggttgtagga atggaactct tcctcataag gggttccaac catggtgcgg acgacagttt
      541 gattggtaaa atcaagaata ctaggataat tggtcaaaaa ataataaatt aaggttgcaa
      601 aatcacgtgc tgttgtgata ttagaagctg ttaaatcata tttttctggg agatagtagc
      661 cttgaaaggc ttgtgcgatt gctccgctag catttgaaaa atgcgtatta gtcatgccga
      721 gctctttggc tgttttgttg atccgatcaa taaaggctga cgcatcgttg ttggataggt
      781 agttggcaat catcactgtt gcagcatttg atgacggaac cactgtcata atgattaaat
      841 cacgaatagg gtacgcaact cctgcaacaa tattattatt gctgatttcg taaattttac
      901 taatcgcctg atcagtctct gttgctgtaa tggtggtatc aagtgttacc tttcctttgg
      961 ccaattcctc aaagaggata taaagcgtaa acatctttga catactagca gggtctctag
     1021 gcatgtcaat gttatcctgc cataagatct ctgaggtctt tgcgtcaaca acaatggagg
     1081 cttttggcct attaacctca ctaacggtat agccagcctt gcgggtaatt tccatgacat
     1141 cttcggcgtg aacctgagaa atgcctagaa agcacaggca caccaaaacg aatagtagca
     1201 atcttttagt caattcaaag ctccttaatg taaaaaaata atgtaagctt attatatcat
     1261 ttcaataata caaatgaaat atattttttg aaaatattaa gggttaatga gaatgccaat
     1321 gactttttga aaaaagtcaa ataatttgct aagtttccct ttttcaggaa tgcttttagc
     1381 tgagacaata gcaacagctg gcggtgctgc tagatagcca ctgtcaatga gcttaggatc
     1441 ctgatagata agggtaccga cctttttatt ttgacgaatt ggggccttga gtgctttgtc
     1501 tttgattcgt agcgagtaag acagctctgt ctggtcctta ggccgaacaa ccgttaaggt
     1561 ttgactagcc ttgaccctta gcctttgctt tgctgcttgt ttaacaatca gtctttcagg
     1621 caaaacttgg ttttgagcaa caagcttttc caaggcatag ctattaaagc aataatcaag
     1681 caggcgattg gtctcaacaa agcgagctcg ctcatcagtg tcagattgat cagcatggag
     1741 aatgacagaa ataactcgca tattatcctg cacagctgtt gcaatcattg tttgtccggc
     1801 ttggctggta gtgcctgttt taaggccatc aaccccagct ctgcccatct cgcgaccggc
     1861 taatagtaga ttagaactag gcaaggcctt ttcaccccat ttcaattggg gctgtgagga
     1921 gatggtgaga agctcaggaa agtcttgaat caactgctgt gcaatcagtg ccagatctct
     1981 agctgtcatc tgattttcat catctggctg tgagcctgga tatagatgcc cctttagcat
     2041 actgttgttt agccctgaag cattgacaag aagatagtct ctaatccccc aagcctccag
     2101 ctgttttttc atcatgtcta caaatgtagg ctctgagcca gcgatatgct ctgctagagc
     2161 tacagcagag ctattagcac taataatcag gctagattca acaagctctt tgatagtgta
     2221 aggtctttgc tcaaatgctg ggttgctgat atcaggatca gtggctaatt gcagagcata
     2281 ttcagatagg gttacctgac tatcccactg gagccgtcct gccttaattt ccttcaggac
     2341 taggtagacg gttagtagct ttgttagaga agcaatgggc gccttttgct gggcctcttt
     2401 ggcatatagg atttttccag ttgtcatttc aaccgcaatg gcttgacgac tattaacaga
     2461 gaagttctca gcaaaggaag tatttgtgat cagacacatg agcgcagcaa gtgtcacaat
     2521 aagttttttc ataccatcat tgtagcaagg aaatagtgat cggtcaaaag gtcattgagt
     2581 acctttaaag aaggctaagt caagactctg agtgagatga cgtccccaaa aatcaagcct
     2641 caaaaaaacc gtctgacatc aacagactaa agctgtcaat tcatacggtt ttgctgtttg
     2701 cagagctttt gtaggcctta gagcttgcta ggagctcttt tagctacctt cttggagagc
     2761 ttgacacaat ggtcaatttt tgcgagataa gcctaatgaa gccctgagtg aggccttggc
     2821 actaatgagg acataaggca taaaagctag tcattagaga tattggttaa cataacgaac
     2881 aaaatgattc caccagacct ttaaaaagaa gctttttggc accttttttt gagccaccag
     2941 ctcaacgctt ggcgcttgac ctagatagcc ttttccgatt aagctatgat cattaagtgt
     3001 ggcctttgcg agtgtttgtc ctttttggat aggcgctact aagggatttt tggtatcgct
     3061 tacttgaaaa gtcgttttgg acttgtcgtc aagcgctttt atcatagtga gcttcttttt
     3121 tggcactagc tggatcttct tttgaggact atctaaaaca ggaagcgctt taagctgatc
     3181 tggtttaccc ttttcaagga caacaacctt tttaaaatgc gtcaaaacat actgcagcaa
     3241 ttggtttgtc gctgtaaaga cggccgtatc gttgtcctgg gcatggtcag cattgaggac
     3301 aactgtaata atacgcatat tgttttcgac actagtggct aaaaaagaag agcctccctt
     3361 ttcagaatag ctaacaaaaa gcccatcaac accatcacga tagttaggca ttccctttag
     3421 catatagttg tatgaaaaaa tctgttgatg attaaactca gcttgaacct gacttgatag
     3481 ctttaaaacc tcaggaaatt cctttaaaag atggctagtg acaagagcaa gatcggctgc
     3541 actaaattga ttatcatcat caagactaga tcccggatag atatgctctc ctagtatgtg
     3601 gttaggcagg ccactagcat tgacgacctt ggcacctgta atgccccagt ctttcaattg
     3661 agcgatcatt ttatcaacaa acttagcctc tgttcccccg attttttctg ccagggcaat
     3721 agcagggcta ttagcattgg tgacaataag agcctttaac agctctttaa cagtatattt
     3781 tctagcatct aagggcacat tgcttatggt gtagttggtg gttagtttgt aagggtagtt
     3841 agagatcgtt acggagctat cccattttaa ctttcctgct tgcacctctt tgtacaccaa
     3901 ataagctgtt aaaaccttgc ttagagaagc cacagaaaca gtcttgtcgg cgtccttttc
     3961 gtatagaatc ttaccgctat caagctcaac agcaatcgca tgcttggcgc taatatcata
     4021 atgatcagcc tgtgctggat aggccagaca agatatggct aatatggtca aagctattaa
     4081 aacctttttc atttgaataa tccttctagt cgttttttta attataccat aatttttcaa
     4141 gaagcttgac taaacctctc agagaagaga gatcattatg agaaaatgct agctgttatg
     4201 atagcgataa cgaactgtat aaaaatagca aataatgtat cttaaacgtc atcagatcgt
     4261 caacagaaaa aatcttgcaa aatattcaga taattttgcg atcgctattt ccatcagcta
     4321 aaatttgtgg tataatagct ccaattaacc aatttcattt atgctgataa atgaaaaata
     4381 acgtttaggg gtgacttcta tgaagaaaag taaatggttg gcaacgctgg gtgtcgcagc
     4441 gctgtcggtg tccatcctgg cagcctgtgg aaacagctca agtaaaagca gtgaatcaaa
     4501 gatttatagc tatgtctatt ctagtgatcc aagtacttta gactatatca gtacaagtaa
     4561 agcaacaaca aatgacataa caacaaatgc tgttgatggg cttttggaaa atgaccaata
     4621 tgggaattta atcccctctc ttgctaagga ttggaaggtc tcaaaggacg gcttgaccta
     4681 tacctacacg cttcgtgatg ggattaagtg gtacacatct gatggagaag agtatgcaga
     4741 tgtgacagct gaggattttg tagctggagt aaagcacgca gcagatgtta actctgatgc
     4801 cctatatatc attcaggact ctattaaagg cttaagcgat tacttgaacg gtaagaccaa
     4861 ggacttttca accgtaggtg tcaaagcgct tgacaaaaaa acagttcagt acacccttaa
     4921 tcaaccagaa agcttctgga attcaaagct aacctatagt gtcctagctc cggtaaatgc
     4981 tgacttctta aaatcaaagg gcaaggattt tggtaaggca acagatccat catctatcct
     5041 gtataatggt ccatttctta tcacagcttt gacaagcaaa tcctctatcg agcttgtcaa
     5101 aaacgaaaat tattgggacg ctaagaatgt tcaccttgat ggtgttcaat tgacctttta
     5161 cgatggacag gatcaggagt cattgtttag aaactttgat gacggtgctt actcagcagc
     5221 gagattattc ccaacaacac cttcttataa aactgttaag aaaaaatatg gagacagtat
     5281 cacttacgga caacaaaatg ctactctcta ctatgcggcg tttaacctaa atcgtacgtc
     5341 ttacaaccac actaagaaga cctcagatag ccaaaaatca gatacccaaa aggctatctt
     5401 aaacaaggat ttccgtcagg ctatgacatt tgcctttgat agaattgctt atcaggcgca
     5461 atcagcaggt gaagatgcag ctaacaaatc gcttcgtagc acacttgtgc caccgacatt
     5521 tgtgaaaatt ggcgacaaaa actttggtga tgttgttgag gagcacttgg tgacctatgg
     5581 tagccagtgg gaaaatgtaa atctagatga tgcacaggat ggcttgtaca atcctgaaaa
     5641 ggcaaaagca tcatttgaaa aagcaaaagc agccctacaa gctgagggtg tacagttccc
     5701 aatccatctt gattacccaa tggatcaaac tgcaacggtg ctcttacagc aggctcgctc
     5761 tatgaagcag tcaattgaga aaacattagg aactgacaat gttgtgattg atattattga
     5821 gcttcagaaa gatgtttatg aaaatattag ttatctcgcc gaaactcctg ctcaaaatga
     5881 ctgggatatt tcaacggctt ctggctgggg acctgattat gtcgacccat cgtcatatct
     5941 tgatattttc aacccaacgc ttgcaaactc acaaacaaaa tcaattggac ttgagccagg
     6001 taaggatttg gccattgcta gtgcagctgg cttagacgaa tttacaaagc tagtgacaga
     6061 ggcaggcaag attactgatg atctcaacgc ccgctacacg ctctatgcta aggctcaagc
     6121 ggcattgaca gactctgcta tttacatccc gactatttca cttggtggaa caccacgtgt
     6181 aactaaagtg gtaccgtttt caggcgcctt tgcttgggct ggtactaaaa atgactttta
     6241 ttacaaatac gtcaagctac aagataagcc tgtaactgct aaacaatatg acaaagcatt
     6301 agccgagtgg aaaaaagaaa agaaaaaatc taacgaaaaa tataataatt ccctcgagaa
     6361 gcatattgaa aaataaattg atgttcatta agaactttct cttagaggag gaagttcttt
     6421 tgaactgctg gggactagaa tgaaaaaata catatttgaa cgcatattga ggtcgcttgt
     6481 ttcaatcctg ctggtaaccg cactaaccta tactattgtc tttaccttag tgccaaaaag
     6541 cttgattttt aagcaagacc ctaattacaa taaaatggtg acaacacctg ataagaaaac
     6601 caattatcta aatactgttt ttgaaaatat gggctatatt tcctattaca gcagtaaaga
     6661 actgcagaat aaggcttcaa agcttgatcc ttctgtaaca actgcaccaa ccaaggccaa
     6721 tgaaaaaata tatcaaaaat atattgcttc tgtcggtaat ggttggaagc ttgggcgctt
     6781 tacagaaagt aagggatttt atgccgttag agagattcca atctatgagc gcgtgtggaa
     6841 tttctttagc catttggttg tgattgatca cccatggaaa atcaaggatc caaaaaatcc
     6901 aaatctagag cgttatgtgc gaccagaaat tgaccctgct gttggtccag ccttagttgg
     6961 ctctggtact aagcacaaat acttgattta cttcaacaag caatttccat ttatccatca
     7021 aaatatcgta acctttgatt tgggagtgtc ctatccaacc tatgccaata ttccagttgt
     7081 tcaggttatc actcaaggac aaggaagaac acttcaaaaa gaggtcacct tcccaacagg
     7141 caaaacaaag ctgtcttcaa tcgatattta ctctcgaacc tataaaacac caagctcttt
     7201 agatagcaag gatattgcca attttggtaa gggtgatgct tataccaata cacaaaataa
     7261 ctatgcagag ccatctatga ttgcaaattc ctttaagatt ggtattgtcg gtgtcttgtt
     7321 gtcctatctt tttggtttgc caattggtat gctgatggct tattataaga atggctggtt
     7381 tgaccgcttt tcaacggctg ccacaacctt tatgttagcc ctgccaagca ttgcgcttat
     7441 ctatattgtt cgatttgtcg gttcttattt gggcttgcca gatacctttc cgctgctagg
     7501 agcaggagat gttaggtctt atgtgctgcc tgctcttata ttaggaattc ttggtacacc
     7561 aagtacagta gtttggttcc gacgctatat tgtggacttg caaggcagtg attttgttcg
     7621 ctttgcacga gcaaaggggc tttcagaatt tgagatttca aaaaatcatc tctttaagca
     7681 ggctatggtg cctattgtta acggtattcc acaagccatt gtcggaacaa ttgccggtgc
     7741 aaccttgaca gaaaccgtct ttgctttccc aggaatgggt aaaatgctga ttgattccat
     7801 aaaagctgct aataactcta tggttgttgg tcttgtcttt atttttgctg ttttatcaat
     7861 attagccttg ctagtaggtg atattcttat gacaatttta gatccacgta ttaaattatc
     7921 aggtaaagga ggtaagtaat ggcagcaatt gacaaaaata aattcacctt tgttgaatta
     7981 gatagctatg catcagaagt cattgatgcc cctgcttact cttattggaa atctgtattt
     8041 agacaatttt tctcacgtaa atcaactatt ttgatgctgg ttattttgat tgctattatt
     8101 ttgatgagct tcatctaccc tatgtttgcc aactatgact ttggtaacgt gagcaatatt
     8161 aatgattttt caaaacgtta tatagcacct aatgcagagt attggtttgg tacggatcaa
     8221 aatggtcaat cgctctttga tggcgtttgg tatggtgcta gaaattcaat cttaatttca
     8281 gttattgcaa ccatcatcaa tatgattatc ggagtcattg tcggtggtat ttggggtgtt
     8341 tccaaagcag ttgataaggt aatgattgag gtgtataata tcatctctaa cctgccgcaa
     8401 atgctcatta tcattgtgtt gacttattct atcggagcag gcttttggaa cttgattttt
     8461 gctttttgtg tgacaggctg gattgggatt gcttattcga ttcgtgtaca aattttgcgt
     8521 tatcgtgatt tagaatacaa tttagcaagt cagaccttag gaacacccac ccataaaatt
     8581 gtcattaaaa atcttttacc tcaattggtt tcggtgatcg tttcgatggt ttccttgcta
     8641 ttgccgtcct atatttcatc agaggccttc ttatccttct ttggcttggg attaccaatc
     8701 acagaaccaa gcttgggtcg attgatttca aattattcaa acaatttaac aacaaatgcc
     8761 tatttattct ggattccatt gacaactctt attcttgttt ccctaccttt atacattgta
     8821 ggacaaaact tagcagatgc tagtgatcca aggacgcata gataggagaa gtcatgactg
     8881 aaaaacaaga aattatatta agtgctaaaa atattgttgt agagtttgat gtgcgtgatc
     8941 gtgtactgac cgctattcgt gatgtttctc ttgatttgta taagggagag gtattggctg
     9001 ttgttggtga gtcaggctct ggcaagtctg ttttaactaa gacatttaca ggaatgctgg
     9061 aggcaaatgg acgtgttgct tcagggacga taacctatgc aggtcaagaa ctaacagagc
     9121 ttaaaaatca taaggactgg gaagctattc gcggctctaa aattgccact atctttcagg
     9181 acccaatgac tagtctagat ccgattcaaa cgattggcag ccagattact gaggttattg
     9241 ttaagcatca gaaaaaatct agatcagagg ctaaggcttt agcaatcgac tatatgacaa
     9301 gggtcggtat tcctgagcca gaaaagcgtt ttggagagta tcctttccaa tattctggcg
     9361 gtatgagaca gcgtattgtt attgccattg ccctagcttg taagccagat attctgatct
     9421 gtgatgagcc gacaacagct cttgacgtta ccatccaggc tcagattatt gacctattaa
     9481 agacgcttca aaaagagtat cacttcacca ttatctttat cacgcatgac ctaggagtgg
     9541 ttgcaagtat tgctgataag gttgctgtta tgtacgcagg ggagattatt gaatacggaa
     9601 aggttgagga aatcttctat gatcctcgtc acccctacac atggagctta ttatctagcc
     9661 taccgcaatt ggcagatgaa aagggcgttc tgttttcaat tccaggggca cctccgtccc
     9721 tatacaagcc aattgttggt gatgcctttg cgccacgctc tcagtatgct atggccattg
     9781 attttgaaga aacagttcct cgttttacga tcagtgacac gcactgggca aaaacctggc
     9841 tcctacaccc agatgctcct aaggttcaaa aaccagctgt tattcaggat ttacaccaaa
     9901 aaatattgaa aaaaatgtca cgccaggagg aaggaaatgt ctgaaaaatt agttgaagta
     9961 aaagacctgg agatttcctt tggagaggga aagaaaaagt ttgttgccgt taaaaatgcc
    10021 aatttcttta tcaataaagg agaaaccttt tctcttgttg gagaatcagg cagtggaaag
    10081 acaacaatcg gtcgtgccat cattggttta aatgagacaa gttcaggcga aatccgctat
    10141 gatggtaaga ttattaatgg taaaaaatca aaatctgaag ctaatgaact gattagaaaa
    10201 atccaaatga tttttcagga tccagcagcc agcctgaatg agcgtgcaac ggttgattat
    10261 atcatctcag aaggccttta taattttaac ctattcaaga cagaagatga acgtaaagaa
    10321 aaaattaaac agatgatgtc agaggtgggc ttgcttgcag agcacctgac acgctaccct
    10381 catgagtttt caggtgggca gcgtcagcgt ataggcattg caagagcgct tgtaatggat
    10441 ccggagtttg ttattgctga tgagccgatt tcagctcttg atgtatctgt tcgtgcccaa
    10501 gtcttgaatc tgttgaagaa aatacagtct gaaaaaggct tgacctattt attcattgct
    10561 catgatttat cggttgtgcg ttttatttca gatcgtattg ctgttattca caaaggagta
    10621 attgttgaag tcgccgaaac agaagagctt tttgttaacc ctgttcaccc ttataccaaa
    10681 tctctgctgt cagcagtacc aattccagat cccattttag agcgtcaaaa gaaattggtg
    10741 gtttatcatc cagagcagca tgactattct gttgacaagc catcaatggt ggaaatcaaa
    10801 ccaaatcact tcgtctgggc taaccaggtg gaagcggagc gttaccgcaa agagctttaa
    10861 gattagttat catcacataa cagaatttag cctcagctag attctgtttt tgccttcctt
    10921 gggtagtctt ttttgttctg acaaggatag aaatatccag cattttccat ctattta
//
LOCUS       DARYNN010000061        10970 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.061, whole genome shotgun sequence.
ACCESSION   DARYNN010000061 DARYNN010000000
VERSION     DARYNN010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10970)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10970)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10970
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.061"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            559..2109
                     /locus_tag="TVB59_001726"
     CDS             559..2109
                     /locus_tag="TVB59_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007893974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEL1010590.1"
                     /translation="MSILEVKQLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGHLQPDAGKIEWSKYVTAGYLDQHTVLEPGQTVRDVLRTAFDELFKTEERIN
                     AIYMSMAEETADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMETEVT
                     SLSGGQRTKILLAKLLLEKPDILLLDEPTNYLDAEHIEWLKRYLQHYDNAFVLISHDI
                     PFLNDVINIVYHVDNRNLVRYSGNYDQFKEVYEMKKAQLEAAYERQQKEIAELQDFVN
                     RNKARVATRNMAMSRQKKLDKMEIIELQAEKPKPSFEFKEARTPSRFIFQTRELVIGY
                     DRPLTKDPLNLTFERHQKVAIIGANGIGKSTLLKSLLGIIQPLSGEVETGDFVELGYF
                     EQETAGVKRQTPLEAVWDAFPALNQAEVRAALARCGLTSKHIESQIQGLSGGEQAKVR
                     FCLLMNREHNVLILDEPTNHLDVDAKEELKRALQVYKGSILMVCHEPEFYEGWVTDIW
                     DFNQLTSL"
     gene            2532..2807
                     /locus_tag="TVB59_001727"
     CDS             2532..2807
                     /locus_tag="TVB59_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010591.1"
                     /translation="MKKSYGIGLGLLLGSAAIAVTYLSLSSAKKKELLKEGSETIEEL
                     NHYIQEKGGQLIETASDKVEASKVAANACGHSAAKAIKGTLEEAIKI"
     gene            complement(3160..4064)
                     /locus_tag="TVB59_001728"
                     /pseudo
     CDS             complement(3160..4064)
                     /locus_tag="TVB59_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515585.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            complement(4174..4824)
                     /locus_tag="TVB59_001729"
     CDS             complement(4174..4824)
                     /locus_tag="TVB59_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEL1010592.1"
                     /translation="MNQTFKQSLPLSVNEEVANSVTHAIGAAAMLILLPITAIYSYQT
                     YDLKAAVGASIFIISLFLMFLSSTIYHSMSYGTTHKYILRIIDHSMIYIAIAGSYTPV
                     ALSLVEGLLGYVIIILQWGITLFGILYKIFAKTINEKFSLALYIIMGWLVVFILPVII
                     QKASLPFGILMLLGGLSYTVGAGFYAKKKPYYHMIWHLFILLASALQVIAIIFYML"
     gene            complement(4808..5263)
                     /locus_tag="TVB59_001730"
     CDS             complement(4808..5263)
                     /locus_tag="TVB59_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEL1010593.1"
                     /translation="MEYDKLPSWKDLPDLELYLDQVLLYVNQVTQLSQATDHKLLTAS
                     MINNYVKHGYIDKPIKKKYQKKQVARLIAISILKNVFPIQDISQVLTSLQAASSSEVL
                     YDTFVNYWNNGLTQSTPEIISYACQTVKDYQHTMKLSREMEDTKHEPNL"
     gene            5524..6279
                     /locus_tag="TVB59_001731"
     CDS             5524..6279
                     /locus_tag="TVB59_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002962809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEL1010594.1"
                     /translation="MSQKEVGHQFLARLGKKRLRPGGVEATNWLVQQGEFSSDCKVLE
                     VACNRCTTSIELAQTYQCHITAVDLDTKVLAEARKAIEAAQMQDYIHLTQANALKLPF
                     ADNSFDIVINEAMLTMLNDAAKEKALKEYWRVLKPGGRLLTHDVSYEADETKAIIEQL
                     RDTINVNVSPLQLDAWRQLLVKSGFTAVNYSYGNMTLMSPLGMIKDEGVVAAIRIMLR
                     GMKKENRKQFLKMRHFFNKTGRKLCYIAAVSQK"
     gene            6307..6645
                     /locus_tag="TVB59_001732"
     CDS             6307..6645
                     /locus_tag="TVB59_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEL1010595.1"
                     /translation="MSLIRKIPTSTVIDLKAEVPIEEDQILSRTLVQRKDLGITLFSL
                     DKGQEIGRHSSPGDAMVNVLSGVVDITIGEACYEVAAGETIIMPANIPHSLFAKEAFQ
                     MLLVVVKPEA"
     gene            6647..6952
                     /locus_tag="TVB59_001733"
     CDS             6647..6952
                     /locus_tag="TVB59_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEL1010596.1"
                     /translation="MLADLLELVRYHDDQIASRSLHQSLGFKQSVVLYAMYQGETISN
                     ESSPEGKLLLVLEGRLLVSLTDQAHDMKAGGLISISAHQFYHLEAATNCKYLQIEMV"
     gene            7703..8440
                     /locus_tag="TVB59_001734"
     CDS             7703..8440
                     /locus_tag="TVB59_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1010597.1"
                     /translation="MNIFILEDDLGQQFRLEMKIQEILDKHHWTCDRFEVYGKPYQLL
                     ANVTERGRHQLFFLDIQIRNDEKKGLAVAREIRKRDPYALIVFVTTHSELMPVSFRYQ
                     VSALDFIDKELSMKHFSDRIERAIIYAYEEQENVTSEGLFIFATAKAQVQVPFSSLLF
                     IETSSTPHKLILHSQNERIEFYGFLSEVLKQDSRLVQCHRSYVINPYNVSFLDRDKRL
                     LYFKNGQSCMVSRLKMKALEASIKALH"
     gene            8813..9013
                     /locus_tag="TVB59_001735"
     CDS             8813..9013
                     /locus_tag="TVB59_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComC/BlpC family leader-containing
                     pheromone/bacteriocin"
                     /protein_id="HEL1010598.1"
                     /translation="MNTKTIEQFSTMTADMLAGVEGGWGYRWRCTDGYTSAWHLLRDT
                     AQENADNHMILYPGTVCRVYNA"
     gene            9080..9934
                     /locus_tag="TVB59_001736"
     CDS             9080..9934
                     /locus_tag="TVB59_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000926579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1010599.1"
                     /translation="MLLILDNISKSYGSKKVLSRISAQFTPGLYGLLGANGTGKTTLL
                     NIISQFTVPDSGEISLNHQQQPKNFYQNIGFLPQQFNYYQQFSGLEFLLYMAALKNVK
                     RKKALVEADRLLKLVGLYDVRKKKIASYSGGMKQRLGIAQALINDPLLLILDEPTVGL
                     DPKERVKFRNIISDLSEQKIIILSTHIVSDVEAVAKEVILLKHGQFIEKGSVDQLVQT
                     MIGKVWEIPVATESAPAFLTDYAVVNEKIVKNNRILRVVSDESPCYQANPVSPTLEDL
                     YIYHFRKE"
     gene            9940..>10970
                     /locus_tag="TVB59_001737"
     CDS             9940..>10970
                     /locus_tag="TVB59_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1010600.1"
                     /translation="MASLIPFEFKKLLRRQSVFGAIVVVLLAVGGLFYQHFFNGQISG
                     SSADQVHGRAAVAINQQIAEKHTGYLSDDLISRILNDYAKNQSDLKKKGVYSVVSHYA
                     ISHLVPKSTDKLIAINSTDKSLTFDNVHLKSREELGSALPLKELKLGNFAPWNQLFDV
                     TNSTYLLVVMLCLYITAPLFSGESSKKMNSILLTTVFGRGKLTLAKLAVSIAVSTLVF
                     AIASGLVFAVFATYFGFSGWDTSLQLNLYWIDPVINIMAFPEKMTLGIAFVYLLVFQY
                     IGLIFMTGIHALVSSLTKSPLTTFGISALIVYAPVFLMGIFPEGLMNKLLTFVSVQTF
                     GTQELLLKLA"
BASE COUNT         3386 a         1872 c         2356 g         3356 t
ORIGIN      
        1 agaaatcatt ttcctttata atgaatgata aggttagctg atacaggaga gtgttttttg
       61 tccttaagtt cgatctgaaa accttgaaac agacgaggcc gaaacaaaag gctgcctcaa
      121 aatagaacaa atgaacaggc ctagttttct gaaattccga aagctagacc tgttcgcttt
      181 ttaatgaatt agactgggca ataaagcatg tcggtcaaga cttgctaaag tgtagctctt
      241 gttgtcatag actctctatg tctttgttgt gagcggcttt ccacaacaaa cgagcgaaac
      301 agttctttcc gaatgatagt ataaattaaa gcaggcactt tcaaggcttt ccctatagta
      361 aaatttataa aataataaga catatttgaa atagctgaac attaaaatgc aaaaaacctt
      421 ctgttcttgc taaaaatctt tcatgcgtat gacgtaggct ttttcagcct tcattgacaa
      481 aaggctgcat ttttgccata attgagagag tgtaagccgt tttaacggct tttttgatga
      541 caataaagga aagtaatcat gagcatatta gaagttaagc agttaagtca tggatttggt
      601 gatcgtgcca tttttgaaga tgtttccttt cgtcttttaa agggcgagca tattggatta
      661 gtaggagcaa atggagaagg caagtccacc tttatgagta ttgttactgg tcacttgcag
      721 cctgatgctg gtaagattga atggtcaaag tatgttacag caggctattt ggatcagcat
      781 accgttttag aacctggtca aactgtgcgt gatgttctta ggacagcctt tgatgagcta
      841 ttcaaaacag aggagcgtat caatgccatt tacatgtcta tggcagagga gacagctgat
      901 gtcgacgcct taatggagga ggtcggagag ctacaggacc gtcttgaaag cagggacttt
      961 tataccctag atgctaagat tgatgaggtt gcgcgtgcct taggagttat ggattttggg
     1021 atggaaacag aagtgacctc cttatctgga gggcaaagaa ccaagattct gctggccaag
     1081 ctgttactgg agaagccaga tattttgctg ctggacgagc cgaccaatta tcttgatgct
     1141 gagcatattg agtggttaaa gcgctattta cagcattatg acaatgcctt tgtgctcatt
     1201 tcacatgata ttcctttttt aaatgatgtc attaatattg tttatcatgt tgataatcgg
     1261 aatttggtta ggtattctgg aaattacgat cagtttaagg aagtctatga gatgaaaaaa
     1321 gctcagctag aggcagccta tgagcgtcag caaaaagaga ttgcagagct acaggatttt
     1381 gtcaatcgta ataaggccag agtagctact cgcaatatgg ctatgtcccg tcaaaagaag
     1441 cttgataaaa tggaaatcat tgagcttcag gcagaaaaac caaagccaag ctttgagttt
     1501 aaggaagcaa gaacaccaag ccgctttatt ttccaaacaa gggagcttgt catcggctat
     1561 gacagacccc taacaaaaga tcccttgaac ttaacatttg agcgtcatca aaaagttgca
     1621 attatcggtg ctaatggtat tggtaagtca accctcctaa agagcctgct tggcattatt
     1681 cagccactgt caggagaggt ggaaacagga gatttcgtgg agcttggtta ttttgagcaa
     1741 gaaactgcag gtgttaagcg tcaaacgcca ctagaagcag tatgggacgc ttttcctgct
     1801 ttaaatcaag cagaggttcg ggcagcctta gctcgttgcg gtctaacctc taagcatatt
     1861 gaaagccaga ttcaggggct ctcgggtggt gagcaagcca aggttcgttt ttgtctctta
     1921 atgaatcgtg agcacaatgt tttaatccta gatgagccaa ccaatcattt agatgtagat
     1981 gctaaggagg agttaaaacg cgccttgcaa gtctataaag gctctatttt gatggtttgc
     2041 catgagccgg agttttatga gggctgggta actgatattt gggatttcaa tcaattaacg
     2101 tcattgtagc agatgtccaa ggtctttatc ttgggcattt ttgctgccta aagcaaaagc
     2161 attgacgata attgtgtatt ttagtaaaat gacaatataa taaataaaaa gcgttgtcac
     2221 tttagatttg atgatagctg agcttatggc ctagcggtaa gtattatcgt aatcaagcta
     2281 gtgcttagct gtatctagac tagtctgaca cgctgatagt tcttagctta cgctgcctaa
     2341 tcaggcagtc tctggcactg cgcaataaaa gacgattgta tggtgcaaac aagaaaaagg
     2401 aaatagcaca tggtgaaaaa acgacgaaaa atcaagtata tggatctttt acaattggtg
     2461 cttttagtag taccagctgt aaaattagct aaaaagatga ttaaggaagg tcatagaaag
     2521 tagggttgat gatgaaaaaa agctatggaa tcggcttagg attacttctt ggttcagcag
     2581 caattgctgt gacatattta agcttatcct cagccaaaaa gaaagagctc ttaaaggaag
     2641 gctctgaaac tattgaggag ttgaaccatt atatccaaga aaagggtgga caacttattg
     2701 agacagcctc tgataaggta gaagcctcta aggttgctgc taatgcctgt ggtcattcag
     2761 cagctaaagc tattaaagga accttagaag aagcaataaa gatataagag tgtcaagcta
     2821 aatcgcctga taatccttta taatatgcga ctgggcttat tgctatagct ggcatcagtc
     2881 aatagagctg cacttacaat gagacacaga gatagctaag gttctctagg attcaaagaa
     2941 aatccccttt ctcgctgttt gtcctgagaa tagaagatcg gactagtcag atagcttctt
     3001 tgttaaagcc gatattatga aagagctagc tgttaagaca agaaaagagt actgcaagcc
     3061 agcaagaaga agccacagct aacgttatag ctatagctta gttttctaaa actcagcttg
     3121 gagatgaatc tatatcaaaa agtgccctag ggcacttttt tactggctaa caataatgga
     3181 aatcgctttt ggaataacct tcaattcaac agggagatca tcagccttat cgccatcaat
     3241 gcgagttcta ggaatggctg attgacgctg atattgtggc aatagcttta gagaatcagc
     3301 ttgaaaatgg ctaatctcct ttaccttgga aaaatccccc cgtctaaagt ctctaatatg
     3361 gcgcaagcat ttcagaaatg atagctggct catcgtgtaa acttgacaca agccatcgtc
     3421 agcttgtgca cctggtgaaa acgatggaag acctgctata gtattggttg tggtaatcaa
     3481 taagaatttg gttttcaagt gaagaacatg atgatggcta attaagctaa ttgcatatgt
     3541 gcggtttcgt tttagtatct taatactatc ctttaaaaag gccaagggcc aaattttcgt
     3601 ttttcttctg tagtcacatt agccgcaata tcagcaagca gacccaaggt taggctagaa
     3661 atcatatagc ccttgtttac cttgcaaata tctacttttt taatcgtgcc agataaaatc
     3721 gtctcaagtg cctcagttag ctggagtgga atgtttaagg cctttgcaaa gttattgaca
     3781 gtgcccgacg gtacgagtcc aataacagaa tgagcaccac cttcataaac acctccaata
     3841 attttattaa gtgtcccatc tccgcctaga ggaatgacta gatcaatatg atcctgtgag
     3901 gattttttgg ctaattgaaa ggcttgatca gcatttttgg gggtaataat ctgaaccttg
     3961 tcttcagaaa aaccattttg aatcagataa tgcttgacct tttcagccag gtcattttct
     4021 ggttttcctg aattaggatt gtaaaaaata tgtaccgttt tcatattgct ttgatccctt
     4081 caactattta ctgcccttta ttatagcatg aatcaagcca ggtgtctggg ggtaagcaag
     4141 cgctcgcgtt taaaaagtag caacagctac tttttacagc atatagaaaa taatggcaat
     4201 aacctgtaaa gcagaggcta aaaggataaa aaggtgccag atcatgtgat aatagggctt
     4261 ctttttagca taaaagcctg cgccgacagt ataggataag ccacctagta gcatcaagat
     4321 tccaaatggc agactggcct tttggataat caccggcagg ataaaaacga ccaaccagcc
     4381 cataataatg taaagcgcaa gactgaactt ttcattaatc gttttagcaa aaattttata
     4441 caaaatccca aaaagtgtga ttccccactg gagtatgata atcacatagc ccaacaagcc
     4501 ctcaaccaag gataaggcaa caggtgtata gctaccagca atagcaatat aaatcatgct
     4561 atgatcaatg atacgtaaaa tgtatttgtg agttgttcca taggacatgg aatggtaaat
     4621 cgttgatgat aaaaacatga gaaataagct gatgataaaa atagatgctc caacggcagc
     4681 cttgagatca taagtctggt aagagtaaat agcagtgatg ggtagcagta tcagcatagc
     4741 agctgctcca atagcgtgtg tcacactatt tgcgacctct tcattaactg atagtgggag
     4801 actttgttta aaggtttggt tcatgcttgg tatcctccat ttctcttgaa agcttcattg
     4861 tgtgctgata gtccttgacg gtttgacaag catagctaat aatttcaggc gttgattggg
     4921 taaggccatt attccaatag ttgacaaagg tatcgtacaa gacctctgag ctggaggctg
     4981 cttgtaggct cgtcaagacc tgactaatat cttgaatagg aaatacattt ttcaaaatgc
     5041 taatagcaat taagcgggca acctgctttt tttgatattt tttcttaata ggtttatcaa
     5101 tatagccatg tttgacatag ttattgatca ttgaagcagt cagtagctta tggtctgtgg
     5161 cttgactcaa ttgtgtgacc tgattgacat agagtaacac ttgatctaag tataactcca
     5221 aatcaggtaa atccttccag ctgggcagct tatcatattc cattactaaa acctctttat
     5281 ctagttttga taactagatt atatattatt taaaaaataa tagcaagtca aaaggtcgta
     5341 tagcacaaga aatatgagcc aattctatga tttatcataa aaacaatcat cagaaatgct
     5401 taagcttcat tgaggatatg ctttaagtgt gatatagttg tagtaatcat ttattgatca
     5461 atttgttaac agttagttta ttctaagtga tgatatatag cagagcaaat aggagggcat
     5521 gtgatgtctc aaaaagaagt tggtcaccag tttttagctc gactgggaaa gaaacgacta
     5581 cggcctggcg gtgttgaggc gacgaattgg ctggttcagc aaggagagtt ttcgagtgat
     5641 tgcaaggtct tggaagtggc ctgcaaccgt tgcacgacct ccattgagct ggcgcagact
     5701 tatcagtgtc atattacagc agtagatttg gataccaagg tactggcgga ggcaagaaag
     5761 gctattgagg cagcacaaat gcaagactat attcacctta cccaagctaa tgccttgaag
     5821 ctgccttttg cagataatag ctttgatatc gttattaacg aagctatgct aaccatgttg
     5881 aatgatgctg caaaggaaaa agcacttaag gaatattggc gtgttttaaa gccgggtggt
     5941 cgcctactaa cgcatgatgt ttcctatgaa gctgatgaaa caaaggctat tatagagcaa
     6001 ctaagagata cgattaatgt gaacgtatcg ccattgcagt tagatgcctg gagacaattg
     6061 ctggtaaaga gtggcttcac agcagtcaat tactcctatg gtaatatgac gctcatgtcc
     6121 ccgcttggca tgattaaaga tgaaggggtt gtcgctgcga ttcgtattat gctgcgcggc
     6181 atgaaaaaag aaaatcgaaa gcagttttta aagatgcgtc atttcttcaa caaaactgga
     6241 agaaagctgt gttatattgc cgctgtaagt caaaaataac tagaataatg gtaaaggaga
     6301 agtgacatgt cattgattcg taaaattcca acaagcacag tcattgattt aaaggcagaa
     6361 gtgccaattg aagaggatca aatattaagt cgaacactag ttcaaagaaa agatttgggc
     6421 ataaccctgt tttcattaga taaaggacaa gaaatcggtc gtcattcatc accgggagat
     6481 gcaatggtta acgtgttaag tggagtagtt gacattacta ttggagaagc ctgttatgag
     6541 gtagctgctg gcgagacgat catcatgcct gctaatattc ctcatagctt atttgctaag
     6601 gaagccttcc agatgctttt agttgttgta aagccggagg cttagcatgt tggctgattt
     6661 attagaatta gtaaggtatc atgatgacca aatagctagt cgttcgcttc atcaaagcct
     6721 aggctttaag caatctgttg ttttatatgc catgtatcag ggagagacga ttagtaacga
     6781 atcaagccct gaaggtaagc tcctgcttgt cttagaagga aggttgctgg ttagtcttac
     6841 ggatcaggct catgacatga aagcaggcgg attgatcagt atctctgctc atcagtttta
     6901 tcatttagag gctgcaacaa attgtaaata cctgcaaatt gaaatggtct aaaagtatag
     6961 agtgactctc ttgaatcttg ccccctaggc tggtgtttta gctgccttag ggggcttttt
     7021 gtgtttagtg tcataaggtt tagctgaaga tctagcttac ttcaaatcac tcaaagtgat
     7081 taataataat aacaattacc tgttttgatg ataaaaagat tgtttttatg ataaaataaa
     7141 tgacagaata tcccggatac ctaatgtatt tgttaccaat aattctagaa acttattgct
     7201 tggagaaggt atagctacaa gcagctaatc atcagatagc ctcagtaacc tgactagcca
     7261 ttgttagttt tccttattta ccatttaaga cataatcagt accatttaag attttaactc
     7321 cctgctccct agctttgtgt tagaatgtct gtgcaaggag atcagtgtgt ggattgatag
     7381 ctgatgactt gtcaaacaaa agtgatagtc gttaagagct ctctctcaaa gaggtatgac
     7441 ttgcggctcg tgctagtata ttatctgtgg taaaaaaatt gtttgaggcg cgtgattcgc
     7501 taaggcctat tgaaaacgct gcaatgacaa gttggttaga agtcattgac aacctttagt
     7561 taataagctt aacggtcatg gttttaatgg tgatgctaaa aagatactgt tcatgaagga
     7621 gagcgttcta gctatcactt gttcaaaaag ctgctttagt ctcctaaaaa aacgataagc
     7681 taaagcaata aggaggttct aaatgaatat ttttattctc gaagatgatc taggccaaca
     7741 gtttaggctt gagatgaaga ttcaagagat attggataag catcactgga cttgtgatcg
     7801 ttttgaagtt tatggaaagc cctaccagct tctggcaaat gttacagaga gaggcaggca
     7861 tcagcttttc tttctcgata ttcaaattcg aaatgatgag aaaaagggct tagctgttgc
     7921 tcgtgagatc agaaagcgtg acccttatgc cctcattgtt tttgtcacca cacattctga
     7981 gcttatgcca gtttcttttc gttatcaggt gtctgctcta gattttatcg ataaggaatt
     8041 gtcaatgaaa catttctcag ataggattga aagagccatt atatatgctt atgaagagca
     8101 agaaaatgta acctcagagg gcttatttat ttttgcaacg gctaaggctc aggtgcaggt
     8161 tcctttttca agcctattgt tcattgagac ctctagtact cctcacaagt tgattttgca
     8221 ttctcaaaac gagcgaatag aattttatgg ctttctttca gaggttctta agcaagattc
     8281 cagactagtc caatgtcatc gttcttatgt tatcaatcct tacaatgttt cgtttcttga
     8341 tcgtgataag cgtttactct atttcaagaa tgggcagtct tgcatggttt caagactaaa
     8401 aatgaaagca cttgaggcgt ctattaaggc tttgcattga cagtaaaaga atgccatgtg
     8461 gaagccatca tttgtttttt aatcaacctc gttgatacca tttaccttaa gggatattta
     8521 ttataaatat atttagtcaa aactaagaaa aaggggtaac agttggtttc taatgatgct
     8581 cagagatatg atgtacatgc aaaaatcaat tatatcataa gaaaagagag aaaaagatat
     8641 agctcgtgaa aggtatccat atgatcttaa ctggtaattt cagaagaaaa attgaccatt
     8701 cacgacaaaa taagaaccat tcaagatttt tgagtgtcgt tgctttaaaa agcgctacac
     8761 taagtttgtc gagactgtag ctagataaaa tcattataag gaggtattcg atatgaatac
     8821 aaaaacaatt gaacaattta gtacaatgac tgctgatatg cttgcaggcg ttgaaggtgg
     8881 ttggggttat aggtggagat gcactgatgg ttatacaagt gcatggcatc tattaagaga
     8941 tacagcacaa gaaaatgctg ataaccacat gattctttat cctggtaccg tttgtcgagt
     9001 atataatgct taatggttaa tcatctgggg agcagcgaag tggtgctgtt ccctgggttt
     9061 ttacttagga ggaatgacaa tgttgttaat actagataat atttctaaat cttatggaag
     9121 taaaaaggtg ttgagtcgta tttctgcaca atttacacca ggcttgtatg ggttattggg
     9181 agcaaatggg accggtaaaa cgactttatt aaacatcatt agtcagttta cagttcctga
     9241 tagtggagaa attagtttaa atcatcaaca acaaccaaaa aacttttacc agaatattgg
     9301 ctttttacct caacagttta attattatca gcagttttcc ggtttagaat tccttcttta
     9361 tatggctgct ttgaagaatg ttaaacgtaa aaaggcttta gtagaagctg atcggttatt
     9421 aaagctggta ggtctttatg atgttagaaa aaagaaaatt gcttcttatt ctggcggtat
     9481 gaagcagcga ttgggtattg ctcaggcact tatcaacgat cctttactgt taattttaga
     9541 tgaaccaaca gtcggacttg atccaaagga acgtgtaaaa tttagaaata ttatcagtga
     9601 tttatcagag caaaaaatta ttatcctatc aacacatatt gtatctgatg tagaagcggt
     9661 tgcaaaggag gtaatccttc taaagcatgg tcagtttata gaaaaaggaa gtgttgatca
     9721 gttagttcaa acaatgatcg gcaaggtatg ggagattcct gttgctacag agagtgcacc
     9781 agcatttttg actgactatg ccgttgtcaa tgaaaaaatt gtaaaaaata atcgtatctt
     9841 acgtgttgtg agcgatgaga gtccttgtta tcaggcaaat cctgtgtcac caacattaga
     9901 ggatctctac atttatcatt ttagaaagga gtgaattcta tggcatctct catacccttt
     9961 gagtttaaaa aattattaag acgacagtcg gtatttggtg cgattgtagt ggtcttattg
    10021 gctgtaggtg gtctttttta ccagcatttt tttaacggtc agatcagtgg ctcttctgca
    10081 gatcaggttc atggacgtgc agctgtagca attaaccaac aaattgctga gaagcataca
    10141 ggttatttat ctgacgatct gattagtcgt atcctcaatg attatgctaa aaatcaatca
    10201 gacctaaaaa agaagggtgt atatagtgtg gtatcacatt atgctatctc tcatttagtg
    10261 cctaagtcta ctgataagct tatcgctatt aatagcactg ataagtctct gacatttgac
    10321 aatgttcatc tcaaatcacg tgaagagttg gggtccgctc tgcctttgaa agagttgaag
    10381 ttaggtaatt ttgctccttg gaatcagttg tttgatgtaa ccaatagtac ttatcttctt
    10441 gttgttatgc tttgtcttta tataacggct cctttatttt caggggaatc atctaaaaag
    10501 atgaactcta tcttattgac gactgttttt ggacgtggta aattgactct tgctaaatta
    10561 gcagttagca tagctgtcag tactttggta tttgcaattg ctagtggtct ggtctttgct
    10621 gtctttgcga cctattttgg ttttagcggc tgggacacta gcttacaact caatttgtat
    10681 tggattgatc cagtgataaa cattatggct ttcccggaaa agatgacctt aggcattgcg
    10741 tttgtctatt tattggtgtt tcagtatatt ggcctgatat ttatgacagg cattcatgca
    10801 ctagtttcat ctctaactaa gtctcctcta accacttttg gtatatctgc tcttattgta
    10861 tatgcaccgg tctttctaat gggaattttt ccagaaggtt tgatgaacaa actgttaaca
    10921 tttgtatccg tacaaacctt tggtacacaa gaattattat taaaattggc
//
LOCUS       DARYNN010000062        10709 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.062, whole genome shotgun sequence.
ACCESSION   DARYNN010000062 DARYNN010000000
VERSION     DARYNN010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10709)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10709)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10709
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.062"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(<1..424)
                     /locus_tag="TVB59_001738"
     CDS             complement(<1..424)
                     /locus_tag="TVB59_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010601.1"
                     /translation="MVKLSKRSKIAMSFLIVFCGIFFVAQKRFGSSDQSFTVRPDADF
                     YIVGYHNIEGYQLTNEQPQKISDAKLEVVKGQINQVVKRAELSNRYLVFSEEGPPLGA
                     IGRLIALDFQKGNVTYHPTADYAFTSSGVSPDYYFTSTA"
     gene            1025..1843
                     /gene="proB"
                     /locus_tag="TVB59_001739"
     CDS             1025..1843
                     /gene="proB"
                     /locus_tag="TVB59_001739"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEL1010602.1"
                     /translation="MMKRQFEDVKRIVIKIGTSSLVLANGKINLEKIDHLAFVISSLM
                     NKGKEVILVSSGAMGFGLDLLKMAKRPSQLAKQQAVSSVGQVAMMSLYSQIFAHYQTT
                     VSQILLTRDVVVFPESLANVTNAFESLISLGIVPIVNENDAVSVDEMDHSTKFGDNDR
                     LSAIVARITRADLLIMLSDIDGLFDKNPTIYEDARLRSHVTEITEDIIASAGGAGSRF
                     GTGGMLSKIQSAQMMFEHQGQMILMNGANPRDILRVLEGEKLGTWFKQIERGDA"
     gene            1843..3090
                     /locus_tag="TVB59_001740"
     CDS             1843..3090
                     /locus_tag="TVB59_001740"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEL1010603.1"
                     /translation="MTIEQLGQRAKAASRALVSLTTKDKNQFLAFLAEELVAQTDMIL
                     TENAKDLAKAAEHGISEILCDRLRLTADRIHAMAQGVRQVADLADPIGEVIKGYTNLD
                     GLKITQKRVPLGVIAMIFESRPNVSVDAFSLAFKTNNAIILRGGKDALYSNMALVRLI
                     RNALEASAITPDAVLLVEDTSHAVAEELMQATDYIDVLIPRGGARLIQTVKEKAKVPV
                     IETGVGNVHIYVDEAADLEMAVKVVINAKTQRPSVCNAAESLIIHEKVGATFIPMLEA
                     AISKVQQVEWRADEQAKALFSKAVLATEEDYAAEFLDYIMSVHLVSSLDEAISWINQY
                     TSHHSEAIITANINAAERFQDLVDSAAVYVNASTRFTDGFVFGLGAEIGISTQKMHAR
                     GPMGLEALTSSKYLINGNGQIRS"
     gene            3110..3526
                     /locus_tag="TVB59_001741"
     CDS             3110..3526
                     /locus_tag="TVB59_001741"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010604.1"
                     /translation="MTRDLKKQETIRDLKTLAFKLESVIEALKELKRWGFFDLFDNGI
                     LTSWVKRQKISAINESLGDVRNLVCRYQKELKVSELRLPSSLSHTRQDKIFDIWLDNS
                     VTDFRVLKETKQVLESAELLYEAVQQALSHLDVKDS"
     gene            3629..4579
                     /gene="rsmH"
                     /locus_tag="TVB59_001742"
     CDS             3629..4579
                     /gene="rsmH"
                     /locus_tag="TVB59_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEL1010605.1"
                     /translation="MTNEFHHVTVLLHEAVDMLDIKPDGIYVDATLGGSGHSAYLLSL
                     LGDKGHLYCFDQDQKAIDHAQEQLKPYIDKGQVTFIKDNFRHLKARLLEHGVTEIDGI
                     LYDLGVSSPQLDERERGFSYKQDAPLDMRMDSQAALTAYEVVNTYDFNDLVRIFFKYG
                     EDKFSKQIARKIEQARAIKPISTTTELAALIKSAKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADASIQRAIELLALDGRISVITFHSLEDRLTKHLFKEASTADAPKGLPFIPD
                     ELKPKLELVSRKPILPSQKELMANNRAHSAKLRVARKVRK"
     gene            4583..4906
                     /gene="ftsL"
                     /locus_tag="TVB59_001743"
     CDS             4583..4906
                     /gene="ftsL"
                     /locus_tag="TVB59_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEL1010606.1"
                     /translation="MVNEKRTQAVSKALQKRIRTFSRVEKAFYATLILTAVTMAVSII
                     YLQSRKLQLQQHITQLNRQISDKRTELNNAKQEVNELSRRDRIVDIAGKAGLSNRNDN
                     IKKVE"
     gene            4910..7165
                     /locus_tag="TVB59_001744"
     CDS             4910..7165
                     /locus_tag="TVB59_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEL1010607.1"
                     /translation="MTKWQRYFLDYVVRDRKTPVQNRLRVGQNMMLLTIFIFFIFMIN
                     FMIIIGTDQKFGVKLSDGAKKVYQETVSVQAKRGTIYDRNGTAIAVDSTTYSIYAILD
                     KSFVSATGEKLFVQPSQYDKVAQILKEQLGMEEKDVIKQLKQKGLFQVSFGPSGSGIS
                     YSTMTTIQKAMEAAKIKGIAFSASPSRMYPNGTFASELIGLASLEENKEDGTKSLVGK
                     MGMEAAFDSILSGEDGIITYQKDRNGNTLLGTGKTVKKPVDGKDVYTTLSEPIQTFLE
                     TQMDVFQSKAQGELASATLVNAKTGEILATTQRPTYNADTLEGLNSKSYSWQNILHQG
                     QFEPGSTMKVMTLAAAIDEKVFNPDETFSNANGLTIADATIQDWAINEGISTGQYMTY
                     AQGFSFSSNVGMTKLEQKMGNDKWMNYLTKFRFGFRTRFGLENEDPGIFPSDNIVTQA
                     MSAFGQGISVTQIQMLRAFTAISNDGVMLEPQFVSRIYDPNTDTYRVSDKEIVGKPVS
                     QKAASETRKYMINVGTDPQFGTLHLKSSGPVVKVGQLPVAVKSGTAQIATKDGTGYLD
                     GGLTNYIYSVVAMVPADEPDFLMYVTLKHPEHWAMVFWQDIINPVLEEAYLMKDTLDK
                     PVAVDTSHEATYQLPDIVGQDTGKSADELRRNLVHPIVLGNGSKIKKVSKKAGTNLAA
                     NQQLLILSNHFDEMPDMYGWTKANVATFAKWTGIDIKYKGSSSGRVVKQSVDVGKALK
                     KVKKITITLGD"
     gene            7167..8174
                     /locus_tag="TVB59_001745"
     CDS             7167..8174
                     /locus_tag="TVB59_001745"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEL1010608.1"
                     /translation="MFLTILAGLIAFAVTALAMPHFIRLYQLKKIGGQQMHEDVKQHL
                     AKAGTPTMGGTVFLLVATSLSFVFALVYFRDGQSLGLISGILLIVLIYGIIGFLDDFL
                     KIFKQVNEGLTAKQKFTFQIVGGLVFYVIHVMPSGIDAINVFGYHWHLGFLYLCFVLF
                     WVVGFSNAVNLTDGIDGLASVSVVISLLAYGVIAYAQGQFDVLLLIGIMVGALLAFFL
                     FNHKPAKIFMGDVGSLALGAMLAAISIALRQEWTLLVIGIVYVLETSSVMLQVTYFKY
                     TKKKYGEGRRIFRMTPFHHHLELGGLSGKAAKWSEWKVDAFLWALGLVASLIVLAILY
                     L"
     gene            8257..9600
                     /locus_tag="TVB59_001746"
     CDS             8257..9600
                     /locus_tag="TVB59_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL1010609.1"
                     /translation="MSFHDYHFKHYIQEALDELGFVEPTEVQQRLIPIVSTGRDLVGE
                     SKTGSGKTHTFLLPIFEKLKEEKEEVQAVITAPSRELATQIFEASRQIAKHSKQEIRI
                     ANYVGGTDKQRQLDKLKLSQPQLVIGTPGRIYDLVKSGDLAIHKASTFVVDEADMTMD
                     MGFLSTVDKIASALPKTIQILVFSATIPQKLQPFLRKYLTNPVIEQIKTETVIADTID
                     NWLLSTKGRDKNEQILATLKAIQPYLAMLFVNTKERADDLHAFLAANGMKAAKLHGGI
                     PPRERKRIMNQVKNLAFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITFYQPSDDSDIKELEKLGITFIPKVLKNGEFQDTYDRDRRQNREKAYQK
                     LDTEMIGLVKKKKKKIKPGYKKKIQWAVDEKRRKQRRAEKRAKGRAERQSRKQSF"
     gene            complement(10241..10696)
                     /locus_tag="TVB59_001747"
     CDS             complement(10241..10696)
                     /locus_tag="TVB59_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010610.1"
                     /translation="MKKAIVSVTLLTVAVLSLSTRFIYSTDYSDLNHKEMARLIQSRK
                     QPVIKYHDNVTINKMITYLAQAKREGILTETFLMNYIFAGEGEYLTKNSRIIADPDGG
                     YWSILEGYEGDGGVKTGIDGVSELNIFSPESTSIGELQEAVLAWYEANK"
BASE COUNT         3027 a         2033 c         2568 g         3081 t
ORIGIN      
        1 ttgctgtaga agtgaaataa taatctggtg atactccgga ggaagtaaag gcataatcag
       61 ctgttgggtg atacgtcacg ttgccttttt gaaaatcaag agcgataagt cttcctattg
      121 cccccaaagg tggcccctcc tcggaaaaga ccagataacg atttgaaagc tctgctcgtt
      181 taaccacttg attgatctga cctttgacca cttcgagctt agcgtcagaa attttttgcg
      241 gctgctcatt tgtcaattga taaccttcaa tattgtggta accgactata tagaaatctg
      301 cgtctggcct tacggtaaat gattggtctg atgaaccgaa tcgtttttga gcgacgaaaa
      361 atataccaca aaagacaatt aaaaatgaca tagctatctt gcttcttttt gatagtttaa
      421 ccatagtgat ttattcctat aactaattaa ttgctttaga tgactgacag gctctgtcgt
      481 cctaagcccc caaactaatt gagaacaatt gagtcttggg attccaaaaa tttaaatgat
      541 acggttttcc tacttgattt ccagcctatt gatttgcgtt ccagtcttgt tgaacactgg
      601 tagcctttgc gccaatgtgc cagacagtat gcctgtgact tgttcttgct acttctgaaa
      661 cgtgttcttt ctgtcaggta ttgcgcttta cagcaaggtc tggcccttag gtagtaaata
      721 tagctgtttg cgctttcatt ttatcgtatt gtgcgttttt gtcaatagct ttagtgttgg
      781 tatatggtca ttaaaaatga caggacaatg caggaggatc agacttaaac ttacaatagg
      841 ataaagcgta gcgtggtatg tggtgtcaca aaggaaatcc tgcttggagt ggctatcagg
      901 tggattttta tatcttaggt gaatgggtag ccagtgatcc ttttttttat caagctgata
      961 ggctgattga ttttggcttc aatctaacag tcctctgggc tgttttttat gctataatcc
     1021 taatatgatg aaacgacaat ttgaagatgt aaagcgtatt gtaattaaaa ttggaaccag
     1081 ctcgctggtg cttgctaatg ggaagattaa cttagaaaag atcgaccatt tagcctttgt
     1141 gatttcaagc ttaatgaata agggaaaaga ggttattttg gtttcctctg gcgccatggg
     1201 ctttgggctt gacctgttga aaatggccaa aagaccaagt cagcttgcca agcagcaggc
     1261 tgtttcaagt gtggggcagg ttgctatgat gagcctttat tcgcaaattt ttgcccacta
     1321 tcagacgaca gtgtctcaga ttttgctgac acgtgatgtg gttgtttttc cagaaagtct
     1381 ggcaaatgtc accaatgcct ttgaaagcct gattagttta gggattgtcc ccattgtcaa
     1441 cgaaaatgat gctgttagtg ttgatgagat ggatcattca acaaaatttg gagacaatga
     1501 ccgcttatca gctatcgtag ctcgtattac aagggctgat ttgctgatta tgctatcaga
     1561 cattgatggt ttgtttgata agaatccaac catctatgag gacgcgcgct tgaggagtca
     1621 tgtgacagag attacagagg atattatagc ctcagcaggc ggtgcaggca gcagatttgg
     1681 aactggtggt atgctaagta agatccaatc agcccagatg atgtttgagc atcaggggca
     1741 aatgattttg atgaatggtg ccaaccctag agacatttta agggtcttgg agggagaaaa
     1801 gctaggcact tggtttaaac agatagaaag aggtgacgcg tgatgacaat agaacagcta
     1861 ggacaaaggg ctaaggcagc tagtagggcc ttggtatcct tgacaacgaa ggataaaaat
     1921 caatttcttg cctttttggc tgaggaatta gtggcccaga cggatatgat tttgacagaa
     1981 aatgccaagg atctggctaa ggcggctgag catgggattt cagagattct gtgcgatcgc
     2041 ttacgcctga cagcagatcg tatccatgcg atggctcagg gcgtcagaca ggtggcagac
     2101 ttggctgatc ccattggcga agtgattaag ggctatacaa atctggacgg cctgaaaata
     2161 acccaaaagc gtgtgccttt aggtgttatt gcgatgattt ttgaaagccg ccctaatgtt
     2221 tctgttgacg cctttagctt ggcctttaag accaataatg ccattattct tagaggtggc
     2281 aaagatgctc tctactctaa tatggccttg gtcaggctta tcagaaatgc cttagaggca
     2341 tcagctatta cgccagatgc tgttttgctg gttgaggata cctctcatgc tgtagctgag
     2401 gaattgatgc aggcaacgga ttatattgat gtcttgattc ctcgtggggg tgccagatta
     2461 attcaaacgg tcaaggaaaa ggctaaggtg ccagtcattg agacgggggt tggcaatgtt
     2521 cacatttatg ttgatgaagc agccgatcta gagatggctg ttaaggttgt gattaatgct
     2581 aagacgcaaa gaccaagcgt ctgcaatgct gcagaaagcc tgattattca tgagaaggta
     2641 ggagcgacct ttattcccat gcttgaagca gccatcagca aggttcagca ggtggaatgg
     2701 cgagcagatg agcaggcaaa agccttgttt agcaaggctg tattagccac agaggaagat
     2761 tatgcggctg aatttttgga ttatatcatg tctgttcatc tggtttcctc tcttgatgaa
     2821 gctatttctt ggattaatca gtataccagt catcattcag aagccatcat cacagctaat
     2881 atcaatgctg cagagcgttt tcaggatctg gttgactcgg cagctgttta tgtgaatgcc
     2941 tcgacacgct ttacagatgg ctttgtcttt ggtctaggag cagaaattgg catttccaca
     3001 caaaaaatgc atgctcgtgg cccgatggga cttgaggcct tgaccagcag taaatacctg
     3061 atcaatggaa atggccagat tcggagctag ctgctaagga ggtaggctta tgacaaggga
     3121 tctaaagaag caagaaacca tacgagacct aaagacatta gcttttaagc ttgagtctgt
     3181 cattgaggca ttgaaagagc ttaagaggtg gggatttttt gatttgttcg acaatgggat
     3241 actaacaagc tgggtaaaaa ggcaaaaaat cagtgctatt aatgagagcc taggggacgt
     3301 gagaaatctg gtctgtaggt atcaaaagga gctgaaggtt agtgagttgc gcttgccttc
     3361 tagcttatct catacaagac aggataagat ctttgatatt tggctagata attcggtgac
     3421 agattttcgg gtgttaaagg agaccaagca ggtgctcgaa tcggctgagc tgctgtatga
     3481 ggctgtgcag caagctctta gtcatcttga tgtcaaggat agctaagcca aaaaaagtaa
     3541 gataaagagg gactttctta ggccttgaaa gcccttttct cttacttttt gatttataaa
     3601 ccctttgaag tatggtacaa ttagagctat gacaaacgaa tttcatcatg taactgtact
     3661 tcttcatgaa gctgttgata tgctggatat taagccagat ggtatttatg tagatgcgac
     3721 ccttggtggc tctgggcact cagcttattt gctgtctctg cttggtgata aggggcactt
     3781 gtattgcttt gatcaggacc aaaaggctat tgatcacgcg caggagcagc tcaagcccta
     3841 tattgacaag ggacaggtga cctttattaa ggacaatttt agacacctta aggcacgctt
     3901 gctggagcat ggggttacag agattgatgg gattttgtat gatttagggg tttctagtcc
     3961 gcagttagat gagagagagc gtggcttttc ttacaagcag gacgctccct tggacatgcg
     4021 aatggatagc caggcggctt tgacagccta tgaggttgtc aatacctatg atttcaatga
     4081 cttagttcgg atctttttta aatatggtga ggataagttc tcaaagcaga ttgctcgtaa
     4141 gattgagcag gcgagagcca ttaagccaat cagcaccacc acagagctgg cagcattgat
     4201 caaatcagct aagccagcca aggagctcaa gaaaaaagga cacccagcca agcaaatctt
     4261 tcaggctatt cgtattgagg tcaatgatga gcttggtgct gctgatgcgt ctatccagcg
     4321 ggcgatagag ctgctagccc ttgatggccg tatctcagtg attacctttc attctttgga
     4381 ggatcgtctg acaaagcact tgtttaaaga agcaagcaca gctgatgctc caaagggact
     4441 tccctttata cctgatgagc tcaagcctaa gcttgaattg gtttcgcgta agccgatttt
     4501 accaagtcaa aaggagctaa tggctaacaa tagggcacat tcagccaagc tacgagtcgc
     4561 aagaaaagtt cggaaataga ttatggttaa tgaaaaaaga actcaggcag tttcaaaagc
     4621 cttgcaaaaa agaattagaa ctttctcgag ggttgagaag gctttttatg ctacgcttat
     4681 cctgacagca gtaacgatgg ctgtaagcat tatttacctg caaagccgta aattgcagct
     4741 ccagcagcat atcactcagc tcaataggca gatctcagat aaaaggacag agcttaacaa
     4801 tgccaagcaa gaggttaatg agctgtcgcg acgtgaccgc attgttgata ttgctggcaa
     4861 agcagggctt agtaaccgaa atgataacat taagaaggtc gagtaagcta tgacaaaatg
     4921 gcaaagatat tttttagatt atgtggttcg tgatcgaaag acacctgttc agaaccgctt
     4981 gagggtgggg caaaacatga tgctcttaac catctttatt ttcttcatct ttatgattaa
     5041 ttttatgatc attatcggga cggatcagaa attcggtgtt aagctatcag atggagccaa
     5101 aaaggtttat caagagacgg tttctgttca ggccaagcga ggcacgattt atgatcgcaa
     5161 tggcacagct atcgctgtgg actcgacgac ctatagcatt tatgccattc ttgataagtc
     5221 ctttgtgtca gcgactggcg agaagctttt tgttcaaccg tctcagtatg acaaggttgc
     5281 tcaaatcctc aaggagcagc tgggtatgga ggaaaaggac gttattaagc agcttaagca
     5341 aaaaggtctt tttcaggttt cctttggtcc gtctggctca ggtatttctt atagcacgat
     5401 gacaacgatc caaaaggcta tggaggcagc taaaatcaag gggatcgcat tttcagcaag
     5461 tcctagccgt atgtatccaa atgggacctt tgcttcagag ctgattggtc ttgcttcact
     5521 tgaggaaaac aaggaggacg gtaccaagag cctagttgga aagatgggca tggaggcggc
     5581 ctttgatagc atcttatctg gggaagatgg aatcatcact tatcaaaagg atagaaacgg
     5641 taataccctg cttggaacag gaaagacagt gaaaaagcca gttgatggta aggacgttta
     5701 taccaccctg tcagagccta ttcaaacctt tctagaaacg caaatggacg tctttcagtc
     5761 gaaggcgcaa ggagagcttg ctagtgctac tctagtaaat gctaagactg gtgaaatctt
     5821 agcgactact caaagaccaa cctataatgc agacaccttg gaggggctaa acagcaaaag
     5881 ctatagctgg caaaatattc tccatcaggg gcagtttgag cccggctcaa ccatgaaggt
     5941 tatgactctg gcagctgcta ttgatgagaa ggtctttaat cctgatgaga cctttagcaa
     6001 tgcgaatggc ttaaccattg ctgatgctac cattcaggat tgggcgatta acgaagggat
     6061 ttctacaggg cagtacatga cctatgctca aggcttttcg ttttcaagta acgttggcat
     6121 gaccaagcta gagcaaaaaa tgggaaatga caaatggatg aactacctaa ctaaattccg
     6181 ttttggattc cggacacgct ttggcttgga aaatgaagac ccaggtattt tcccttctga
     6241 taatattgtt acccaagcaa tgagcgcttt tggtcagggg atttcggtga cgcaaattca
     6301 aatgcttaga gcctttacag ccatctctaa tgacggtgtg atgctagagc ctcaatttgt
     6361 tagtcgcatt tatgacccaa atacagatac ttaccgggtg tcagacaagg agattgtcgg
     6421 aaagccggtg tcccaaaagg ctgccagtga aacacgaaaa tacatgatta acgttgggac
     6481 tgacccacaa tttggaaccc ttcatttgaa atcatcaggt ccagtggtta aggttggtca
     6541 attaccagtt gctgtcaagt cagggactgc gcagattgcg actaaggacg gtacaggtta
     6601 tttagatggt ggcttgacaa actatattta ttcggtggtt gctatggtgc cagctgatga
     6661 gcctgatttt ctgatgtatg tcacactgaa gcacccagag cattgggcaa tggtgttttg
     6721 gcaggatatt atcaaccctg ttttagagga agcctatttg atgaaggata ctttagacaa
     6781 gccggttgct gtagatacca gtcacgaggc tacttatcag ttgcctgata ttgttggcca
     6841 agatacagga aaatcagctg atgagctacg cagaaatctg gttcacccta ttgtccttgg
     6901 caatggcagc aagattaaaa aggtatctaa aaaggcaggg accaatctag ctgctaacca
     6961 acagcttctg attttatcaa atcattttga tgagatgcct gatatgtacg gctggactaa
     7021 ggctaatgtg gctacctttg ctaaatggac tggcattgat atcaagtaca agggatcaag
     7081 ctcgggacgt gtcgttaaac agagcgttga tgtcggaaaa gcgctcaaaa aagtcaaaaa
     7141 aattaccata actttaggag attaacatgt ttttaaccat tctagcaggt ctgatagcct
     7201 ttgctgtgac tgcccttgcc atgcctcact ttataaggct ttaccagttg aaaaaaattg
     7261 gggggcagca gatgcatgag gacgttaagc agcatttggc taaggctgga acacctacaa
     7321 tgggaggaac agtttttctt cttgttgcta caagcttatc ctttgtgttt gctttagtct
     7381 attttcgaga tggacaaagc ctaggcttga tttcggggat cttgttgatt gtattgattt
     7441 acgggatcat aggcttttta gatgatttct taaagatctt caagcaggtt aatgaaggcc
     7501 ttactgccaa gcaaaaattc acgtttcaga ttgttggagg cctggtcttt tatgtgatac
     7561 acgtcatgcc aagtggtatt gatgcgatta atgtctttgg ttatcattgg catttgggct
     7621 ttttatacct atgctttgtt cttttttggg tggttggctt ttcaaatgcg gtcaacctga
     7681 cagacggtat tgatggtctg gcctcggtat ctgttgtgat tagcctgctg gcctatggtg
     7741 ttatcgctta tgctcaggga caatttgatg ttttgctctt gataggtatc atggttggtg
     7801 ccttgctggc ctttttcttg tttaaccata agccggccaa aatttttatg ggtgatgttg
     7861 gaagcttagc cttaggagca atgctagcag cgatttctat tgcgcttcgt caggaatgga
     7921 ccttgctggt tattgggatt gtctatgttc ttgagacaag ctcagtcatg cttcaggtta
     7981 cttactttaa atacaccaag aaaaaatatg gtgaaggccg tcggattttt aggatgactc
     8041 cttttcatca tcatctggaa ttaggcggct tgtccggtaa agcagccaag tggtctgaat
     8101 ggaaggttga tgccttccta tgggctcttg gtcttgtagc cagtctcatt gttttagcga
     8161 ttctttattt gtaagcggct ggggcagtgc ttgaggcacc gccttttgct catctcaagc
     8221 actaatagta ttatcagaaa gaaaacgagg taaataatgt catttcacga ttatcacttt
     8281 aagcattata ttcaagaggc cctagatgag cttggctttg tagagccaac agaggttcag
     8341 cagcgtctta tcccgattgt cagtacagga cgagacttag tgggtgagtc aaagacaggc
     8401 tcaggaaaga cgcatacctt tttgctgcct atttttgaaa agctcaagga ggaaaaagaa
     8461 gaggttcaag ctgtgattac agcacctagc cgggaactag caacacagat ttttgaggcc
     8521 agcaggcaaa ttgctaagca ttctaagcag gagattcgta ttgctaatta cgttggaggg
     8581 acagacaagc agcgtcagct tgacaagtta aagcttagtc agccccagct tgtcattgga
     8641 acgccaggtc gtatctatga tctagtcaag tcaggagatt tagccattca taaggcctct
     8701 acctttgttg ttgatgaggc tgatatgaca atggatatgg gctttttaag cactgtggat
     8761 aagattgctt cagcactgcc aaagactatc caaatacttg tattttcagc aaccattcca
     8821 caaaagctac agcccttttt aaggaagtat ttgaccaatc ctgtcattga acagatcaag
     8881 acagaaaccg ttattgcaga tacgattgac aactggctgt tatcaaccaa gggacgcgat
     8941 aaaaatgagc aaattttggc gactctaaag gctatccagc cttatctggc catgcttttt
     9001 gtcaatacca aggagagagc tgatgactta catgcctttt tagcagctaa tggtatgaag
     9061 gcagccaagc ttcatggagg tattcctcct agagagcgca agcgtatcat gaatcaagtc
     9121 aaaaacctgg catttgaata cattgtggca acggatttgg cggcgcgtgg tattgatatt
     9181 gagggggtta gtcatgtgat taacgacgcc attcctcaag acctatcctt ttttgtgcat
     9241 cgtgtggggc ggacaggtag aaacggcctg ccagggacag ccattacctt ttatcagcca
     9301 agtgatgatt ctgatatcaa ggagctggaa aagctaggca ttacctttat accaaaggtt
     9361 ttaaaaaatg gtgagtttca ggatacttac gatcgtgatc gtcgccagaa tcgtgaaaaa
     9421 gcttatcaga aattagacac tgaaatgatt ggcctggtta agaaaaaaaa gaaaaaaatt
     9481 aaaccgggct ataaaaagaa aattcaatgg gcagttgatg aaaagcggcg caagcagcga
     9541 cgagcagaaa aacgtgccaa gggacgagca gagcgtcagt ccagaaagca aagcttttaa
     9601 gacaggtgct tggtaaagat catccgttca agaaaaatta gatcaaaaag tttttagcga
     9661 tcattctaag ctgatatgaa cagaatcctt gacagagctg agtcaaggaa ctgtgattag
     9721 gtcccaaagc tgtttaggga ttgtttttaa aggcttcaac tctgttcagt gtcccatgtc
     9781 aaatggtcct gtcgttgcgt gcaaggattt caatctacgc tcccgcaaaa ggtgtgataa
     9841 aagtattgtt acatttgaaa ttgtcgaacc tacttcaatt gttacagcaa ctatctttga
     9901 agcgtggcaa ctaaaaccag ctattaacaa ctaaagccgc acctttggct gtcagaatag
     9961 tgattgaaat taacgggttg atacgctttg acacaccagc cttaaattac ttcctctgtg
    10021 ggagtgtaga ttaaggtgta ttaatgtttg aggaggagct tgctcctctt ttttgcttgt
    10081 tcagctcaat gtctctctga aggctatggt tttggttaga tggtaagcac taaaaaacct
    10141 tataagcatt gagcatgggt ctgaccattt caatgcctat aaggcctatg attagctaat
    10201 attagctatt atatgaagca gtcggttaac taagctgcgg ttacttatta gcctcatacc
    10261 aggctagcac cgcttcttga agctctccga tgctggtaga ttctggacta aagatattga
    10321 gctctgagac gccgtcaata ccagtcttaa caccgccatc tccctcataa ccttctagga
    10381 tactccaata ccctccgtca ggatcggcaa taatccttga atttttagtc aggtactcac
    10441 cctctccagc gaaaatataa ttcatgagga aggtctctgt cagaatgcct tctcttttag
    10501 cctgagctag gtaagtaatc attttattaa tggttacatt gtcatgatac ttaattactg
    10561 gttgttttct tgactggata agacgtgcca tctccttatg atttaaatca gaataatcag
    10621 tggagtagat aaatcttgtt gataagctta aaacagctac tgttaacaaa gtaaccgata
    10681 ctattgcctt tttcatagaa aacctcctt
//
LOCUS       DARYNN010000063        10564 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.063, whole genome shotgun sequence.
ACCESSION   DARYNN010000063 DARYNN010000000
VERSION     DARYNN010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10564)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10564)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10564
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.063"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(3..1337)
                     /gene="trmFO"
                     /locus_tag="TVB59_001748"
     CDS             complement(3..1337)
                     /gene="trmFO"
                     /locus_tag="TVB59_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEL1010611.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAKRGIPVKLYEMRGVKATPQHK
                     TTHFAELVCSNSFRGDSLTNAVGLLKEELRRLDSIIMRAGEAHRVPAGGAMAVDREGY
                     AKAVTAELENHPLIEIIREEVIDIPSDAITVIATGPLTSDSLAEKIHALNGGAGFYFY
                     DAAAPIVDKSTINMDRVYLKSRYDKGEAAYLNCPMTKEEFMAFHEALTTAEEAPLNAF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYKGPRDGDFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLEHAEFVRYGVMHRNSYMDSPKLLTQG
                     FQSRANHRLFFAGQMTGVEGYVESAASGLVAGINAARLFKEEEPLVFPNTTAIGSLPY
                     YITHADSKHFQPMNVNFGIIKELDGPRIRDKKERYEAIAKRALADLAAYLTV"
     gene            complement(1719..2432)
                     /locus_tag="TVB59_001749"
     CDS             complement(1719..2432)
                     /locus_tag="TVB59_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3307 domain-containing protein"
                     /protein_id="HEL1010612.1"
                     /translation="MQGLSDYLYQHPILVLLVICHFLSDYHLQSQVIADKKEEQLAYL
                     GLHLLGVAAPLFLVVMCIPKLWLTAILIFSSHAVIDYFKPKWARIIKLDRSWVFVLDQ
                     LLHLFIILALVARVNQAEIPDWLHARQLLLVLFMVLITKPVNIIFKLCFNKFQPASDK
                     PMDTIVGAGAAIGNLERIVMGVCMVLGQFASIGLVLTAKSIARYNKISESPAFAEYYL
                     IGSLFSVLSVFIAAWMCFF"
     gene            complement(2453..3100)
                     /locus_tag="TVB59_001750"
     CDS             complement(2453..3100)
                     /locus_tag="TVB59_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1010613.1"
                     /translation="MLYIAVIGDLVHSKQIQSRSLVQESLKACLDQLNHDFSSYIVSN
                     LSVTLGDEFQGLLTNDAPVFQLIDLINQAMTGYPVRFGIGQGTILTDINPDISIGADG
                     PAYWRAREAIHYIHQKNDYGNTQVAIRTDKEHKDLVLNSLLAAGEAIKASWRASQLEV
                     FHALLDLGIYEEQFDQQLIGDTLDLQSSALSKRLKSSSVKVYLRSRHAALTYLQE"
     gene            complement(3215..5347)
                     /gene="topA"
                     /locus_tag="TVB59_001751"
     CDS             complement(3215..5347)
                     /gene="topA"
                     /locus_tag="TVB59_001751"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEL1010614.1"
                     /translation="MVTKTATKSKQETKRSATKKKSAAAKKNLVIVESPAKAKTIEKY
                     LGRQYKVVASVGHIRDLKKSSMSIDFDNHYEPQYINIRGKGPLINALKKEAKNAKKVY
                     LASDPDREGEAISWHLSHILGLDPDDNNRVVFNEITKDAVKEAFEGPRKIDMDLVDSQ
                     QARRVLDRIVGYSISPILWKKVKKGLSAGRVQSVALKLIIDREHEIKAFVPEEYWSID
                     GLFKKGTKKFQASFYGLNGKKMKLNTNDDVKLVLSRLSSDDFMVSKVEKKERRRHAPL
                     PYTTSSLQQDAANKINFRTRKTMMVAQQLYEGISLGPNGTQGLITYMRTDSTRISPVA
                     QNDAAGFIVERFGSQYSKHGNRVKNATGAQDAHEAIRPSNVNHTPEAIAKFLDKDQLK
                     LYTLIWNRFVASQMTAAVFDTVKVNLEQNSVLFVANGSQMKFDGYMAVYNDSDKSKML
                     PEMTEGEVVKKVTLTPEQHFTQPPARYSEASLIKTLEENGVGRPSTYAPTLDVIQRRY
                     YVKLAAKRFEPTELGEIVNQLIVEFFPDIVDVKFTADMEDKLDQIEIGKEAWQNVIDQ
                     FYKPFVKELTKAETEIEKIQIKDEPAGFDCELCGHPMVVKLGRFGKFYACSNFPECHH
                     TKAITKEIGVSCPACQQGQVIERKTKRNRIFYGCDRYPECDFTSWDLPVGRSCPKSGD
                     YLVEKKIRGGKQVVCSNEVCDYKEEIVK"
     gene            complement(5448..6293)
                     /gene="dprA"
                     /locus_tag="TVB59_001752"
     CDS             complement(5448..6293)
                     /gene="dprA"
                     /locus_tag="TVB59_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEL1010615.1"
                     /translation="MNNFELYKLKKAGLTNLNILNLIDYQQRNNKSLSLRDMAVVSCC
                     KNPVLFIETYKQLNVALLKKEFNQFPSLSILDKQYPLALREIYNPPVLLFYQGDLSLL
                     EKPKLAVVGSRESSEIGTRSVYKIIKELKNHFVIVSGLARGIDTSAHLACLKAGGQTI
                     AVIGTGLDRYYPKENHQLQEFLSQRHLVLSEYGAGEAALSYHFPERNRIIAGLSRGVL
                     VVEAKQRSGSLITCQLAMEEGRDIFVVPDNILNGTSAGCLKLIKDGASCVTHGRDILS
                     EYHYS"
     gene            complement(6539..7321)
                     /locus_tag="TVB59_001753"
     CDS             complement(6539..7321)
                     /locus_tag="TVB59_001753"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEL1010616.1"
                     /translation="MTAMTIKDIKARLEAVSSLSDPFFEELKADKRLGVQKAVSSRKR
                     ALEAILKEEARLEAMLTYEQALYQKGFQAIAGIDEVGRGPLAGPVVAACVILPKGCTI
                     KGLNDSKKIPKAKHEAIYQAIQKKALGIGLGIIDNHTIDRVNIYEATKLAMTAAINQL
                     EGSVSKPDYLLIDAMTLEVSIPQQAIIKGDASSMSIAAASIVAKVTRDRLMLDYDKAF
                     PGYGFAKNAGYGTKEHLQGLHQYGVTPIHRQSFEPIKSMILR"
     gene            complement(7302..8156)
                     /gene="ylqF"
                     /locus_tag="TVB59_001754"
     CDS             complement(7302..8156)
                     /gene="ylqF"
                     /locus_tag="TVB59_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEL1010617.1"
                     /translation="MATIQWFPGHMSKARRQVQENIKHVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLMLLNKADLADNTHTKKWQQYYEKQGIKTLAINAKEQATVKRVTEAAK
                     ELMADKLRRLRERGIQKETLRTMIIGIPNAGKSTLMNRLAGKKIATVGNKPGVTKGQQ
                     WLKSNKELEILDTPGILWPKFEDELVGLKLALTGAIKDQLLPMDEVTIFGLNYFKKYY
                     PNRLLKRFKAIDLEADAPEIIMSLTRQLGFKEDYDRFYSLFIKDIRDGRLGQYTLDQV
                     GDDDSNDY"
     gene            complement(8749..9381)
                     /locus_tag="TVB59_001755"
                     /pseudo
     CDS             complement(8749..9381)
                     /locus_tag="TVB59_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(9383..10150)
                     /locus_tag="TVB59_001756"
     CDS             complement(9383..10150)
                     /locus_tag="TVB59_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HEL1010618.1"
                     /translation="MEQKLNHLAVGEFVLLLPEHLRSEEEHYKSVFEDDLTSRMSSQD
                     GRQQMIATVAYLESGQDRFVYNTTPISYQQFLKDPIIIVVTPQSTGPQSVMFWFDAVQ
                     NYVLFNQLSDAQELIQRQDIENWVSEMQSGYQNYITLLNNIQRERWIMLAGAVLGIAT
                     SILLFNTMNRLYFEEFRRAIVIKRIAGLRFLEIHRNYLLAQLGVFLLGFVASVFLQVE
                     IVIAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            complement(10432..10564)
                     /locus_tag="TVB59_001757"
                     /pseudo
     CDS             complement(10432..10564)
                     /locus_tag="TVB59_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795769.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
BASE COUNT         3119 a         2382 c         1936 g         3127 t
ORIGIN      
        1 gattataccg ttaaataagc tgccagatca gctaaggcac gtttagcgat agcttcatag
       61 cgttcctttt tatctctgat acgaggtccg tcaagctctt taataatacc aaaattgaca
      121 ttcattggtt gaaaatgctt gctgtccgcg tgtgtaatat aataaggcag gctgccaatt
      181 gctgttgtat ttggaaaaac aagtggctct tcttccttga atagccgagc agcattaatg
      241 ccagccacaa gtccagaagc tgctgactcg acatagccct ccacaccggt catctgacct
      301 gcaaagaaaa gcctgtgatt agcgcgtgat tggaagcctt gtgtcagaag ctttggtgaa
      361 tccatatagg aattacggtg catcacaccg taacgcacaa actcagcatg ctcaaggcct
      421 ggaatcattt ggaaaacccg cttttgctct ccccatttta aatgtgtctg aaagcccacg
      481 atattataaa ggctgcctgc agcattatcc tgacgcagct gcacaacagc atagggcgtc
      541 ttgaaatcac cgtcacgtgg tcccttgtaa tcatctggat attccaagcc aaccggcttc
      601 attggaccat aaagcatagt cttaatccca cgctttgcca taacctcaat tggcatacag
      661 ccttcaaaat acttttcctt ttcaaaagca tttaaaggag cttcctctgc tgttgtcaaa
      721 gcctcgtgaa aggccataaa ctcttccttg gtcattggac agttcagata agcagcttct
      781 cccttatcat atcgcgattt taaataaacc ctatccatgt taatggttga cttatcgaca
      841 attggagctg ctgcgtcgta aaaataaaag ccagcaccac catttaaggc atgtattttt
      901 tcagcaaggc tgtcactggt caaggggcca gttgcaatta ctgtaatagc atcgctagga
      961 atgtcaataa cctcctcacg aatgatttca atcagagggt gattttcaag ctcagctgta
     1021 acagccttgg catagccttc gcgatctaca gccattgctc ctccggcagg gacacgatgg
     1081 gcttcgccag cacgcataat aatcgaatcc agacgacgca gctcttcctt taaaagccct
     1141 actgcgttgg ttaagctgtc accacgaaaa gagttggagc aaaccaattc tgcaaaatgg
     1201 gtggttttgt gttgcggtgt tgccttgaca ccacgcatct catatagctt aacaggaata
     1261 ccacgcttag caatttgata agctgcctct gatccagcta gaccagcacc aataacatta
     1321 atataagatt gagacaatag accaatacct ctttggggac ttatccatca ctgattgccc
     1381 cgcaactctt tctttcaagt aattaccctg cctattataa cagaaataag agcaaagcaa
     1441 aagaaggagc tgaacagcct cagtctttta tataaaggag ataagcccgt acctgcacgc
     1501 tctccacaaa gctagctgct tcaagcattt tagctttcgc ccaataccag ctatccacat
     1561 atcttgttca ctgcagtagt tactggaagg ctttttaagg cttatttttc aaaatctagc
     1621 caaaaatatt tcaccggacc tcatcatctt gctggtagca gctaaacaag ccttttccag
     1681 taaaaaaaaa gcaagcgaaa gcctgccctt gttcttgttt agaaaaaaca catccatgct
     1741 gcgataaaga cacttaagac actaaacagc gatccaatca aataatattc agcaaaggct
     1801 gggctttcag agattttatt gtagcgagca atagacttag cggtaagcac cagtccgatt
     1861 gaagcaaatt gtcccaacac catacaaacg cccataacaa tacgctctaa attaccaata
     1921 gccgcacccg cccctacaat ggtatccatt ggtttatcac tagctggctg gaatttattg
     1981 aagcagagct taaagataat attgacaggc ttggtgatca aaaccataaa aagcactaac
     2041 aataactgcc gagcatgtaa ccaatcaggg atctcagcct gattaacacg agcgactaaa
     2101 gccagaataa tgaaaagatg caagagctgg tccaacacaa agacccacga ccgatcaagc
     2161 ttaatgatac gagcccattt tggcttaaaa taatcaataa ccgcatggct actaaaaata
     2221 aggatcgctg ttagccaaag cttaggtata cacatcacca ctagaaacaa tggagcagct
     2281 acccctaata agtgcagccc cagataagca agctgctcct ccttcttatc agcaataacc
     2341 tgactctgaa ggtgataatc tgataaaaaa tgacaaatca ctagcagcac taaaatagga
     2401 tgctgataaa ggtaatcaga taagccctgc ataggtggct cctttcctct ttttattctt
     2461 gtaggtaggt caaagctgca tggcgacttc taagataaac ctttacactg ctgcttttta
     2521 agcgctttga caaggcactt gattggaggt ccaatgtatc gccaatgagc tgttggtcaa
     2581 attgttcttc atagatccct aagtctaaaa gcgcatgaaa cacctctaat tgactagcac
     2641 gccagctagc ttttatcgcc tcaccagctg ctaaaaggct attgagcacc agatccttgt
     2701 gctccttatc agtccgtata gctacctggg tattgccata atcatttttt tgatgaatgt
     2761 aatgaatagc ctctctggca cgccaatagg ctggaccgtc agcaccaata ctaatatcag
     2821 ggttaatatc agtcaaaata gtcccctgtc caataccaaa cctaacaggg tagcctgtca
     2881 tggcttgatt aattaaatca atgagttgaa aaacaggcgc atcattagtc aacaagcctt
     2941 gaaattcatc acccagagtc acagataagt tagagacgat ataggaagaa aaatcatggt
     3001 tgagctgatc cagacaggcc tttaaggact cttgcaccaa agaacgcgac tgaatttgct
     3061 tagaatggac caaatcccca ataacagcga tatatagcat gattttccct ccttttatga
     3121 cttccattat aacagacaaa aaccaaaaag tccattataa tggaaaatca tctatatttc
     3181 cgttataatg gacctctgct aaaatagttc aaacctactt tacaatctct tctttatagt
     3241 cacagacttc attgctacac acaacctgct tacctccacg aatttttttc tcaacaaggt
     3301 aatcgcctga cttcggacaa gaccgtccta ccggcaaatc ccacgaggta aagtcacact
     3361 cagggtagcg gtcgcagcca tagaaaatac ggttacgctt tgttttgcgc tcaatgactt
     3421 ggccttgctg acaagctgga caagaaactc caatttcctt tgtgatggcc tttgtatgat
     3481 ggcactcagg aaagttacta caagcataaa acttgccaaa tctacccagc ttaacaacca
     3541 tcgggtggcc gcacagctca caatcaaaac cagccggctc gtccttgatt tgaatttttt
     3601 cgatctccgt ttcagccttg gttaactcct taacaaatgg cttgtagaat tggtcaatca
     3661 cattctgcca ggcttctttg ccgatctcta tctgatcaag cttatcttcc atatcagctg
     3721 taaatttgac atcaacaata tcagggaaga attccacaat caattgatta acaatttcgc
     3781 ctaattccgt cggctcaaag cgtttagcag ccagcttaac ataataacga cgctgaatca
     3841 catcgagtgt tggagcatag gttgatggcc ttccaacacc gttttcttcc agtgttttaa
     3901 tcaggcttgc ttctgaataa cgagctggcg gttgagtaaa gtgctgttca ggtgttaagg
     3961 taaccttttt aaccacttct ccttctgtca tttcaggaag catcttgctt ttatcagaat
     4021 cattgtaaac agccatataa ccgtcaaatt tcatctgact gccattggca acaaaaagga
     4081 cactattttg ctctaggtta accttaacag tatcaaacac agcagctgtc atctgactag
     4141 cgacaaagcg gttccaaatc aaggtataga gctttagctg atccttatct aaaaatttag
     4201 caatagcctc tggcgtatgg ttcacattag atggtcgaat agcctcatga gcgtcttgag
     4261 caccagtagc atttttaact cgattgccat gcttagagta ctgactaccg aaacgttcaa
     4321 caataaagcc tgcggcatca ttttgagcaa ctgggctgat acgagtagag tccgtacgca
     4381 tgtaagtaat taacccttgt gttccattag gaccaagact aatcccctca taaagctgct
     4441 gagcaaccat cattgtttta cgagtccgaa agttaatctt attggctgcg tcctgctgca
     4501 atgaggaggt tgtataaggt aaaggagcat gacgcctgcg ttcttttttc tcaaccttac
     4561 taaccataaa atcatcgcta cttaatcgag acaaaacaag cttaacatca tcattggtat
     4621 tgagcttcat ctttttgcca ttgaggccgt aaaagcttgc ttggaatttt tttgtccctt
     4681 ttttaaagag accatcaatt gaccaatatt cttcaggaac aaaggcctta atctcatgct
     4741 ctctgtcaat gattagcttt agagcaaccg attgcacgcg ccctgctgaa agcccctttt
     4801 taaccttttt ccagagaatt ggcgaaatgg aataaccaac aatacgatcc agtacacgac
     4861 gtgcctgctg tgagtcaacc aaatccatat caatttttct tgggccttca aaagcttctt
     4921 tgacggcatc ctttgtgatt tcattgaaaa cgacacgatt gttatcatca ggatcaagtc
     4981 ccaaaatatg tgataaatgc catgaaatgg cctctccctc acgatccggg tcacttgcta
     5041 gataaacctt tttagcattc tttgcttctt tttttaaggc attaatcagc ggacccttac
     5101 cacgaatatt aatatactgt ggctcataat gattgtcaaa atcaatagac attgatgatt
     5161 ttttcaaatc acgaatatga ccaaccgagg caacgacctt atactgacgt cccaaatatt
     5221 tttcgatggt tttagcctta gcaggtgatt caacaatgac tagatttttt ttagcagctg
     5281 ctgatttttt ctttgtagca gatcttttcg tctcttgttt tgacttagtt gctgtttttg
     5341 ttaccaattg acacacttcc tataacagtt atggttaaag cttctagcat aatatcccat
     5401 tttttaagaa ctgtcaacaa aaaattttct ataaatagga agaaaagtta agaatagtgg
     5461 tattctgaaa gaatgtctct gccatgagtg acacagctgg caccatcttt gatcagcttc
     5521 aaacagcccg ccgatgtccc attaagaata ttgtcaggta cgacaaaaat atcacgtccc
     5581 tcttccatag ctagctgaca ggtaatcaaa gagccagagc gctgcttagc ctcaacaaca
     5641 aggacacctc gactaagacc tgcgataata cggtttcttt cagggaaatg ataagacaag
     5701 gcggcctctc cagccccata ttcactgagc acgagatgac gctgagataa aaactcctgt
     5761 agctggtgat tttcctttgg atagtagcga tctaggccag tcccgataac agctatggtt
     5821 tgcccacctg ctttcaagca agcgagatga gcactggtat caatacctct agcaagcccg
     5881 ctgacaatga caaagtgatt cttaagctct ttgatgattt tgtaaacaga ccgcgtccca
     5941 atttcactgg attctctaga gccaacgact gccagcttag gcttttctaa caggcttaaa
     6001 tcaccttgat aaaagagtaa aacaggagga ttatagattt ccctcagggc caatgggtat
     6061 tgcttatcta ggatagataa gctcggaaac tggttgaatt ccttttttaa caaggcgaca
     6121 tttaattgct tgtaggtctc aataaataaa actggatttt tgcagcaaga aaccactgcc
     6181 atatctctaa gggatagaga cttgttatta cgctgctggt agtcaatcag gttaagaata
     6241 tttaaattag ttagcccagc cttttttaat ttataaagtt caaaattatt catcactgta
     6301 cctctctaat gatttattcg taaaaaaatt aaaaaagctc tgactaaaca aagctttttg
     6361 caaactcttg aggagctgta caggattcca gcaaaaaaat cgaggcctcc tagcctttgt
     6421 atgagcattg tagggcagct catcacatag cattccattg aaaaatacca gaattgtaga
     6481 tccacctagt ggctatcgtt tttgctttcg gcagctacct tttctcaaaa tgagattttt
     6541 agcgtaagat cattgatttt atcggctcaa agctttgccg atgaattggt gtgacaccat
     6601 actggtgcaa tccctgcagg tgctccttgg tcccatagcc ggcattttta gcaaagccat
     6661 agcctggaaa ggccttatcg taatcaagca tcaatcgatc tctggtaacc ttagccacaa
     6721 tagaggctgc agcgattgac atagagctcg catcgccttt tataatagcc tgttgaggaa
     6781 tagaaacctc tagtgtcatg gcatcaatga gcaggtaatc aggcttactc acagagccct
     6841 ccagctgatt aatggcagct gtcattgcta attttgttgc ttcatagata ttaacccggt
     6901 caatggtatg gttgtcaata attccaagac cgattcccaa cgctttcttt tgaatggctt
     6961 ggtaaattgc ttcatgctta gctttaggaa tttttttaga atcatttagc cccttaatgg
     7021 tgcagccctt tggcagtata acacaggctg ctacaactgg tccagccaga ggacctcgac
     7081 caacctcatc tataccagca atcgcttgaa agcctttttg gtaaagcgcc tgttcatacg
     7141 tcaacatcgc ctcaagccgg gcttcctctt ttaagatagc ctctaaagcc ctttttctgc
     7201 tagatacagc cttttgaacg ccaagccgct tatccgcctt tagctcttca aaaaatggat
     7261 cagaaagact agaaacagct tctagacgag ctttaatgtc tttaatagtc attgctgtca
     7321 tcatcaccaa cctgatctaa ggtgtactga ccaagtcttc catcacgaat atccttgatg
     7381 aataagctgt aaaaacgatc atagtcttcc ttaaagccaa gctgacgtgt caaggacatg
     7441 atgatttctg gagcgtcagc ctctagatca atagccttaa aacgctttaa taggcgatta
     7501 ggataatact tcttaaaata attcaatcca aaaatcgtga cctcgtccat tggcaacagc
     7561 tgatccttaa tagcccctgt cagggctaat tttaacccaa ccaattcgtc ttcaaacttt
     7621 ggccataaga tacccggagt atccaatatc tctagttctt tattggattt tagccattgc
     7681 tgtcccttgg tcactcctgg cttattgcct actgtggcaa ttttttttcc cgccaagcga
     7741 ttcatcaggg ttgatttgcc agcatttgga atgccaataa tcatggttcg tagcgtttct
     7801 ttttgaatgc ctcgttctct taagcgacgt agtttatctg ccatcaattc cttagcagcc
     7861 tcggtgaccc ttttgaccgt agcctgttcc ttagcattga tagctaatgt cttaatccct
     7921 tgcttctcat aatattgttg ccatttctta gtatgcgtgt tatctgctag atcagcctta
     7981 ttaagaagca ttagcttggg cttatctcca acaattttgg tcagcatagg attttgactt
     8041 gataaaggta gcctagcgtc tactaaaatc gtcacaaaat caacatgctt aatattttcc
     8101 tgtacctgtc tccttgcctt ggacatgtgt ccaggaaacc attgaatcgt agccatgtgt
     8161 gtaaaatcct ttcgtatcaa gggtttttag cccctcgtct tttaaaaatc atgcgagtca
     8221 ccaaaaaatc accaaatatt aagcattatc tccagaccaa gcgatataat tgcaacttgt
     8281 tttggttatt tttaatgcca acaatatcaa atgatttcta atggtatctg gcttatagct
     8341 attctctgct gaatagattg cctcttcaat tttaccctgt aatctcgctc agcctgtctc
     8401 ctgaccttgc ttttacatat gaaactgtaa tattttccat tttaccagtt atatgataaa
     8461 gaaaatcaaa atagtcgtag tagaataaat tactttaaac tattatagca cgatttccct
     8521 tattttactg ctaaattatc ctttgtaaaa gaagatatta atcgttataa agaccaaaaa
     8581 agagaagacc aaaatgatcc cctctagtct tcttttcggc atattttacc gttatttggc
     8641 caactttcca ctaatgtgag taaaattgta ttctaagcaa gctttaccta ttaacttagg
     8701 agaaaacata atctctatag ctaaaaatac caaaaaaatt atgaatcatt atcgcaaact
     8761 atccatagtg atcacttcat cagccatttc ccatattgct ggattatgag ttgctacgat
     8821 gattaatctg ttagcgtcac gaagagacag tacaatctcc ataatcaact tggacgtggt
     8881 tggatctatt gaagccgttg gttcatctgc caaaataaat ggcggatttt ttaagatgat
     8941 ctttgctaag gcaactcgtt gtgactaacc cccagatagc tcaaaaatgc gtttatctag
     9001 gttcagatag gataaaccta cacgttctaa ggcctgtttc tgtctcatcg tttgctcaga
     9061 tttattcaat ttttgaccaa tgagaccaag tttgaggttt tcttcaatcg tttgattttc
     9121 aatcaaacca aaattttgga ataggtaacc caattcatga cggaaaaaat cactagattt
     9181 atagctggct aagtctttgt ctcggtaaaa aatagtccca tgataaggtt ctaatttccc
     9241 catcatgttc atcaaggttg ttttcccgct accgcttgaa ccaatcaaag catagacttt
     9301 tccaacctca aatgtcattg aaagattaga aaatagctct cgttctccaa aagatttact
     9361 cacttgttta agttcaatca tgttaacctc ctttcaaaac aagcatggac atcttgtttt
     9421 ctttctgcat ttgaacatgt aattgtaaaa gagataggcc agtgaagagc aacaatacta
     9481 agaaagcaat cactatctct acttgaagga atacactcgc aacaaatccg agtaaaaaga
     9541 cacccaattg agccaggagg taattccgat ggatttctaa aaatcttagt ccagcaatac
     9601 gtttgatgac aatggcacgt ctaaattctt caaagtagag cctattcatg gtgttaaaca
     9661 acaagattga ggttgctatc ccaagcacag ctcccgcaag cattatccaa cgttccctct
     9721 ggatattatt caacaatgtg atgtagttct ggtatcctga ttgcatttct gagacccaat
     9781 tttcaatgtc ctgtctctgg ataagctcct gggcatcgga caactgatta aagaggacat
     9841 aattctgtac cgcgtcaaac caaaacatga cggactgagg tccagttgac tggggtgtta
     9901 cgacaatgat aatcggatct ttcagaaact gttgatagga aataggtgtc gtattataca
     9961 caaaacggtc ttggcctgat tccaaataag ccaccgtcgc aatcatttgc tgtcgaccat
    10021 cttgactaga catgcgacta gttaagtcgt cttcaaaaac agatttgtaa tgttcttcct
    10081 ctgaacggag atgctcaggc aagagcaaga caaattcccc tactgcgagg tgattcagtt
    10141 tttgttcaat agccgtatct acagggatgt tttgacgctc caagtattgc ggtgtgacaa
    10201 taaggacatt gccatttggg ctgtaatctt gccattctgt agaagttgtc aagtttttgg
    10261 aaaagtctta gcctttgtta tcaatacttg agtagcacct atgtttttca gattagcttg
    10321 ctcttgtaac tgttctgagc tattaaatgc tgtcatttca acggtgatat tttcagttga
    10381 ttctgcctgc ttgttatctt cttttgttgg agattctgga cgtttctcaa aataaaaata
    10441 attataaagc tgttgagccg ttactcctcc accagcccag ccagcaacag gttgaccatt
    10501 cttcagatat agtattgttg gtgttcctgg gattccaact gttttaaata aaaactcctg
    10561 agct
//
LOCUS       DARYNN010000064         9980 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.064, whole genome shotgun sequence.
ACCESSION   DARYNN010000064 DARYNN010000000
VERSION     DARYNN010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9980)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9980)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9980
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.064"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(484..2061)
                     /gene="cls"
                     /locus_tag="TVB59_001758"
     CDS             complement(484..2061)
                     /gene="cls"
                     /locus_tag="TVB59_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEL1010619.1"
                     /translation="MTIKKNKKVRYLLHKGKKGLLRGIFSRTTIIAALIVLQIFFLCQ
                     SYAWMEQYRVLIAIIERIFSISIVLYLVNSDMDAISRVTWLILIMIAPLLGSLFLIYT
                     KLDWGYRDLKQRINHLVDLSSPYLRDDDAILQALKGHTSTTYHLVQYLERSRGNFPIY
                     RKTQATYFPIGEAFFEGLKTQLLLAKSYIFLEFFIIAEGQMWGEILGILEKKVQEGVE
                     VRVLFDGMLELSTLSADYAARLERIGIKAKSFLPISPFISTYYNYRDHRKIVVIDGEV
                     AFTGGINLADEYINEVKRFGHWKDAGLMLKGEAVDSFLIMFLQMWSITEKRLIVEPYL
                     SQHTEEVASDGYVIPYADSPLDTDKIGRNVYIDILNHAKEYVYIMTPYLILDSETEHA
                     LRFAAERGVDIRIIMPGKPDKAVPYALAKTYYKGLITSGVKIYEYSPGFVHSKVFISD
                     DSKAVVGTINLDYRSLYHHFECATYLYRSSVIADIVQDFKETQASSKLVTESQLRQRP
                     WYQKLVGLLVKTIAPLL"
     gene            complement(2277..5617)
                     /locus_tag="TVB59_001759"
                     /pseudo
     CDS             complement(2277..5617)
                     /locus_tag="TVB59_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677995.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
     gene            complement(5931..7601)
                     /locus_tag="TVB59_001760"
     CDS             complement(5931..7601)
                     /locus_tag="TVB59_001760"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018375545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEL1010620.1"
                     /translation="MKSDIEIAQSVPLKPITEIVKKVGIDADDLELYGNYKAKLSFEK
                     IKSVEDNKPGKLILVTAINPTPAGEGKSTMSIGLADALTKIGKKTMLALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTAHNALSALIDNHLQQGNELGIDPRR
                     IIWKRVLDLNDRSLRQVIVGLGSPVNGVPREDGFDITVASEVMAILCLATDLKDLKAR
                     LANIVIAYRYDKSPVYVRDLKVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATSTALRLADYTVTEAGFGADLGAEKFLNIKTPNLPKAPDAVVIVATLRAL
                     KMHGGVAKADLTFENTAAVRSGFANLKRHVENIRKFNIPIVVAINEFVTDTKAEIQVL
                     KELCAEIAVPVELASVWAKGADGGIALANAVVKAITEESAAYKRLYADKDSLEEKLKA
                     IVTEIYGGRAVQFGPKAKNQLKQFAQFGWDQLPVCMAKTQYSFSDDPSLLGAPDQFDI
                     TIRELVPKTGAGFIVALTGDVMTMPGLPKIPAAMKMDVTEDGTAVGLF"
     gene            7799..8491
                     /locus_tag="TVB59_001761"
     CDS             7799..8491
                     /locus_tag="TVB59_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEL1010621.1"
                     /translation="MAMKLLITSGGTTEAIDAVRGITNHSTGQLGKIVAETFLAKGFD
                     VTLVTTKTSVKPAQQPHLTIREVTNVDQLMAILKEEVPKHDLLIHSMAVSDYSPVYMT
                     DFDTVAAADHLQTFLTASNKEAKISSAADYQVLFLKKTPKVISYIKEWNPNIRLVGFK
                     LLVNAPAEELISVARDSLHKNKADYIVANDLADIKANQHKAFLVNDKTVCSASTKEEL
                     AQLIYERIIAND"
     gene            8484..9029
                     /gene="coaC"
                     /locus_tag="TVB59_001762"
     CDS             8484..9029
                     /gene="coaC"
                     /locus_tag="TVB59_001762"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEL1010622.1"
                     /translation="MTKRITLAVSGSISAYKAADLTSQLTKKGYEVTVLMTQAATAFI
                     TPLTLQVLSKNPVHLDVMAEHDVKIVNHIELAKATDLFVLAPASANTIAHLAYGFADN
                     MVTSVALALPEATPKLIAPAMNTNMYLNPITQGNIKRLADLGFREIPPKTALLACGDR
                     GPGALADIDDMVTAISQQLAR"
     gene            9086..9658
                     /locus_tag="TVB59_001763"
     CDS             9086..9658
                     /locus_tag="TVB59_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEL1010623.1"
                     /translation="MNHNKSSEISRIAIFFAVMLVIHFISSWFFYIWPVPIKPTLVHI
                     PVIVASIMYGPRTGAILGGLMGIVSVITNTLVLLPTSHLFSPFVTNGNLASLMIAMLP
                     RILIGITPYYCYKLIKNELGLVLAGLVGSLTNTIFVLSGIFIFFPTASGDNVKTFLTT
                     IVSGNAITEMIVSAIVTITLIPALSKLKKS"
BASE COUNT         2913 a         2223 c         1869 g         2975 t
ORIGIN      
        1 tgacagagtg tttcctgaat ttttatattt ttcctctata aacttttctt gaaaaatttc
       61 ttttctgcaa ctatcgctat ggctttccta tttttcagaa caagttttcg catttcagaa
      121 atatcttgga aattttttct tcatgcgttt gtcgtagcta gaagcttatg gtatgacagt
      181 caatagataa gtttttcaca tcagtgctat tgttccatga taacataccc ccttagaaaa
      241 ggcagttatg ctatggatac gatgagactc acacctaaca cagtgagatg actaaacatc
      301 acaacaaaaa aagctgagag aaactctcag ctctcagggg cattcgtatc acgaatgtga
      361 taaaaaggtt cacacaaatt atcaaagtcg gctcctgcct taatgacctc cccagcacaa
      421 ctgtgattta aaaatcacaa tcgactcatc gcataggcct attatagcaa acatatcatc
      481 tctttacaag aggggggcta ttgttttaac caataaacca acgagctttt gataccaagg
      541 cctttgcctt agctgacttt ctgtgactag cttagagctt gcctgggttt ctttgaaatc
      601 ctgaacaatg tctgcaataa cagaggaacg gtaaaggtag gtggcgcatt caaaatgatg
      661 atagaggctg cgataatcca gattaatggt tccaacgact gccttagaat catctgaaat
      721 aaagacctta gaatgcacaa atcccggact atattcgtag attttaactc ctgaggtgat
      781 caagccttta tagtaggttt tagcaagggc ataaggaaca gccttgtcag gcttacctgg
      841 cataataatc cgaatatcca cccctcgctc tgctgcaaat ctgagggcat gctctgtttc
      901 gctatccaaa atcaggtatg gagtcatgat ataaacatat tccttagcgt gattcaagat
      961 atcaatatag acatttctgc caattttgtc agtatcaagt ggtgagtctg cataaggaat
     1021 gacatagcca tctgaggcga cctcctctgt atgctgggac agataaggct ccacgatcag
     1081 ccttttttcg gtaattgacc acatttgtaa aaacatgatc aaaaagctat caacagcctc
     1141 accctttagc ataagacctg cgtccttcca atgcccaaag cgtttgacct cattaatgta
     1201 ctcatcagct aggttaatac cgcctgtaaa ggccacctct ccatcaatca ccacaatttt
     1261 acgatgatcc cgataattgt agtaggttga aataaaaggc gagatcggca aaaaagactt
     1321 tgctttgata ccaatgcgtt caagtctggc agcataatcc gctgataagg tcgacagctc
     1381 tagcatgcca tcaaaaagaa cgcgaacctc tactccctct tgcaccttct tttctaaaat
     1441 tcctaaaatt tctccccaca tctgcccctc tgcaatgata aaaaattcta gaaaaatata
     1501 ggacttagcc aataaaagct gagtttttaa accttcaaaa aaggcttctc cgatgggaaa
     1561 gtaggtggct tgagtcttgc gataaatggg aaaattccca cgactacgct ctaaatactg
     1621 aacgaggtga taggtcgttg aggtatgccc cttcaacgcc tgtaaaatag cgtcatcatc
     1681 tctcaagtaa ggagaggaca aatcaactaa atggttaatt cgctgcttta ggtcacgata
     1741 accccagtct aatttagtgt aaataagaaa taaagagcct agtaaagggg ctatcataat
     1801 gagaatcagc caggtcaccc ttgaaatagc gtccatatcg ctattcacca agtacaagac
     1861 aattgaaatc gaaaaaatac gctcaataat agcaattaaa acacgatact gctccatcca
     1921 agcataggat tggcataaaa agaagatttg cagaacgatc aaagcagcaa taatggttgt
     1981 tctgctgaaa atccccctca gcaagccttt tttcccttta tggagcaggt atcttacttt
     2041 tttattcttt ttgatagtca accctccagc tttatttttt cttattatat cataaaactg
     2101 gaggtcatga tttaagtcgc tgctaaaagt ttcagcaatt ggtgcaagca ttaaaaaaag
     2161 acctcaatac ttcttttaca acttgtaatc ctcacaaaac ctactgcttt aacaaccaaa
     2221 aaaagattga aggagacatg cttccccttc aatccaagtc tcatcaggtg atgagattaa
     2281 ttatctgatt tctttttaaa taagcctaga gataggctag ctagtagcat acctaagcct
     2341 gctaataacg atgagcccta tgcctgctct gaggttttag gaagctcatg gctatgtgct
     2401 ggagccattg gtttgctgct atctggtgtc atggctagtg actgctgatc tgctttgcta
     2461 ttatcagaag actgatcttg atcagtagaa ccattgccct taggctgctg ctctggcatt
     2521 ggtgtctcag gctgtttgtc gtctttaatc tctggttcct tttggtttaa aaggtctgta
     2581 agagcaatcg cgttaaagtt gccaaattca tcttcaacaa ttaatgtcaa ggcagcaata
     2641 ttaacctcta cctcctcacc tgacagctct gacatcaccg ttgctggaat gctaaatgag
     2701 ccgtcctcag ccattgggaa gtagttcacc acaatatctg cttcctctcc ttctccaatc
     2761 tcgacaatat ggccaacctg aatacggtag gctgagaatt tagcagtgtc gatcttaagt
     2821 gttctggtag attcgtcata ggaagctgat tttggtagct ctggtaggct tgttttcact
     2881 tgaaccttaa agtcttgctt ttgagcctca gcaccatctg ctacaggagt ataccaaacg
     2941 cgataggtat agctaccatc tgctacaggc tgatcattgg cgtcttttcc actccatttt
     3001 gtatgctcaa agcgatacgg taacacaaca ccctcttgat agtatttctg ggctgaagaa
     3061 acaccacttt cccaaacgat ttgtccattg tgatcaagaa cctgagcttt aatatcctta
     3121 acgcttctta ggaatacccc ttggaagaga ataaaatcct tattaccatc atcatttgga
     3181 gaaatcaaga aggttctatc tgcctctttt gctattaaat ccttttgatc agctgactcc
     3241 tgtgttccta aaataatata tctttctgcc tcagggccta actcattgac cgttccattt
     3301 tttgtatcct gtgccaagaa atatgggctg acctgaccaa tcaaagcagt tagcttgctg
     3361 aatttctctg gtaatatgta tttacctgtt tcaggatctt gctcaagctt ttgataaaag
     3421 gcaccctgct caagcgtctc ataaatagga gtatctaagg ctggcaagtt agcaaaatca
     3481 cccctaaagc cactaaatgg aatactcatc aattcttcct tagtgtctaa attgtctgtg
     3541 aaacggacaa agccttcaag gaagtagcca tttggcattg cttttaacaa ttcagcagcg
     3601 taagccttag cgtcaacaga aacttgaata tgctgctggt cctcggtgat attaatttcc
     3661 tgccactctg aatcctttaa tgcttttggc tgcaaggtga agtgaccatc tttagtttga
     3721 tcagtgatta ggttgacttg gaaataaagc tttttaggcc cttgattttt cgatagggca
     3781 ttaacattta gattaatgac aaattcatct gcaatgttcc ccagattgat tttagggttt
     3841 tgcttctgat cagtaaggta atagctggct gctagtgcct tttgaccatc tacctcacca
     3901 gcaccctgct ggcgtggaga aatataagcc ttgttttctg tgctataaag tgttcttgct
     3961 gagctcatca acacagctct aacaagctga gaaagctcct tatcagaaag ctctgggaat
     4021 ttctctttgt aagctttatg tagcatggcc acaagccctg acaccatagg tgttgacatg
     4081 cttgtaccag tcttgtaatc atattggtta ccatgaactg cagagtagac attgacacca
     4141 ggtgctgaaa tatctggctt gatacgacct tctgctgtca caccccagct ggattggctg
     4201 ataacgcggc caccagcatt gctaagcatt ttctcatagg ccttattaaa tctaaagctt
     4261 tgaccttcct taagagcttg agcgtccttg tagctcataa agccaacagg aatgtgagct
     4321 tcctttggaa tagaggcctt ttcaatcgta aagcttcctt caagcgcatt gttattgtag
     4381 ataatcacac cgctagcacc agctttaaca gcattttcaa tcttttgata aaagctaagt
     4441 gagccgccac gttcaatcaa agcaaccttg cctttaatat caagaccagt aaagtgagag
     4501 gcttcaccga atttggcatc agccacaaag taatcctgat cagcatcaaa tgagtcgccc
     4561 tctgacataa agatcgctag tttttgacta ccgtctgcgg tcttagcatt aacagactgg
     4621 ctaatagcgt aaacaggatt ggaagccgca acactgataa cctcttcaaa aatagctgga
     4681 ctattaaggg taccaaaatc aggatttgct gctagaggct ctcgagttcc cataccaact
     4741 gcactctcat taccagctcc agcaaccaac aaaacaccct tttcttgagc ataggctata
     4801 gcctttttaa cgtcctcatg aaccgttgat aaggaatccg ctgtttttcc aaagctcatg
     4861 ctaatcactg tagctcctag attaaccgcg tctgtgatcg ccttagcata ggattttgca
     4921 aattgatccc tttctggggc accagtcacc ttcatcagca taagagaagc atttggtgca
     4981 atcccctcaa cacgaaggcc atttcctgct ggtgttttcc cattacctgc tgctatagcg
     5041 gcagtatggt taccatgacc attatcagcg gtcaagccgc caatatcatc tgattgcttg
     5101 gtgtaatcgt aggcaaaaat aattttttcg ttgtaccact taccgtatgt gattttctga
     5161 tcctgctttt tagcaagaaa tgcctcttta gcaggaatag tatcgctatt ttttaagtcc
     5221 gaatcaagct taaaggcgtc atgctcagga tcaaaggaaa catcaataac agcaataacc
     5281 gctccgcttc ccttttgtgt ttactcttgt agggctttag cgttgaccga gtcattcagt
     5341 gataaattgg tcggtgctgt gctctctggg ccttctgcaa aggctgatat ttctttttct
     5401 gttttagctt ctgtttctga agtcgcctgg ctgcttgaga attgtcatcc gtagcagtag
     5461 cttcaacagc tgcaactgga ttcacttgtg atacagaagc gtctaagtcc tgctgctcct
     5521 cagcaaatac agtctgacta tgaagcaata aaatacttgt tgtagccaat gttaactggc
     5581 ataataaact tttctttgag tgatattttt tagtcactaa taaaacctcc atttgtacct
     5641 gactataata atataacaat atctctttat taacaataga tttgtgaaaa attaatttta
     5701 tcatttaata ttaaaagtca gattattaaa aaatatccct accaaagcag aattaaagca
     5761 ttaatgattg tcaatatgac acctatactg gtaaaaaaag attgtgaata acgattaaaa
     5821 tagtaaaata tgagctattg ttatcagctt atccttagac attaaaaaag attgaagaaa
     5881 ccccctttct gaagctttct tcaatcctga ttctggctat aacaaataaa tcaaaacaat
     5941 cctactgctg taccgtcttc ggtgacgtcc atcttcatag ctgcaggaat ctttggcaag
     6001 cctggcattg tcatcacatc tccagttaag gcgacgataa agccggcacc ggtcttaggc
     6061 actaattcac gaatggtaat gtcaaactga tctggcgcgc ctaggagcga tggatcgtct
     6121 gaaaagctat actgggtttt ggccatgcaa acaggcaatt gatcccaacc aaactgggca
     6181 aattgcttga gctgattttt agctttaggt ccgaattgca cagccctacc accataaatt
     6241 tcagtcacaa ttgccttaag tttctcctct aagctatcct tgtctgcata tagacgctta
     6301 taggctgcgc tttcctctgt aatagccttg acaacagcgt tggcaagagc aataccgcca
     6361 tcagccccct tggcccacac gcttgccaat tcaaccggaa cagctatttc tgcacacaat
     6421 tcttttaaga cttgaatttc tgctttagta tctgtcacaa attcgttgat agctacaaca
     6481 atcggaatat tgaattttcg aatattctca acatgacgct ttaaattagc aaagccagac
     6541 cggaccgcag ctgtattttc aaaggttaaa tccgccttag caacaccgcc atgcatcttc
     6601 aaggcacgaa gtgttgcgac aataacaact gcatcaggag ccttaggtag attcggtgtt
     6661 ttgatgttaa ggaatttttc tgctccaaga tccgctccaa agcctgcctc tgtaacagta
     6721 taatctgcca accgcaaagc tgttgatgtc gccagaacag aattacagcc atgagcaata
     6781 ttggcaaagg gtccaccatg cacaaaggct ggtgtaccat agattgtttg aacaaggtta
     6841 ggcttgatgg cgtccttcaa aatcaaggct aatgcccctt ctacctttaa atcacgcaca
     6901 tatacaggtg atttatcgta acgataggca atcacaatat tagctaaacg agccttcaag
     6961 tccttaagat cagtcgccaa gcaaaggata gccatcactt cagaggctac tgtaatatca
     7021 aaaccgtctt ctcttgggac accattgaca ggactcccca agccaacaat gacctgccta
     7081 agagaacggt cattcaaatc aaggacacgc ttccagatga tacgacgcgg gtcaatacca
     7141 agctcattgc cctgctgaag gtgattatca ataagggctg ataaagcatt atgagctgtg
     7201 gtaatagcat gcatgtcccc ggtaaaatga aggttaatat cttccatcgg aagaacctga
     7261 gcgtagccgc cacctgcagc accacctttg atccccataa ccggtcctaa agagggctca
     7321 cgcaaggcca gcatggtttt tttaccgatt ttagtcaagg catctgccaa accaatagac
     7381 atggttgatt tgccttcacc tgctggcgtt ggattaatag cagtcactaa aatgagctta
     7441 ccaggcttat tgtcctctac tgatttgatt ttttcaaagg ataatttggc tttgtagtta
     7501 ccgtaaagct ccaaatcatc agcatcaatc cccacctttt taacgatttc tgtaatcggc
     7561 tttaagggga cactttgagc aatttcgata tctgatttca tgaaaactcc ttgactctta
     7621 cttgatagtg ttattatatc acacttcatc tcaaacgtac attgatttgt tctatataca
     7681 aaaatgttcg tttttataat ggttctgaaa ggaaaaaagc ttagtagcgt cagcattgtc
     7741 agtaaaaata attttaatta gtgattttat ttactattct tgctttttct gataaaatat
     7801 ggctatgaaa ttattaatca catcaggcgg aacgaccgaa gcaatagacg ccgttagagg
     7861 gattaccaat cattccactg gccagctagg aaagatagta gctgagacct ttctagcaaa
     7921 gggatttgac gttactctag tgacaacaaa aacttcagta aaaccagcac agcagcctca
     7981 tttgaccatt cgtgaggtga ccaatgttga tcagctgatg gctatcttaa aagaggaggt
     8041 tcctaagcac gaccttctca ttcacagcat ggctgtttca gattatagcc cagtgtacat
     8101 gacagacttt gatacagttg cagctgctga tcatttacag acctttttaa cagcaagcaa
     8161 taaggaagcc aaaatctcat cggcagctga ttatcaggtg ctctttctta aaaaaacacc
     8221 taaagtcata tcctatatta aggaatggaa tcctaatata aggctagtcg gctttaagct
     8281 attggtcaat gctccagctg aggagctaat ttcagtggca cgagatagcc tgcataaaaa
     8341 caaagcagac tatatagtag ccaatgacct agcagatatt aaggccaatc agcacaaggc
     8401 ttttcttgtc aatgacaaaa cagtctgctc tgccagcacc aaagaggagc ttgcacaatt
     8461 aatctatgaa aggataatag ccaatgacta agcgaataac acttgcggtc tcaggtagta
     8521 tttctgccta taaggcagct gatctcacca gccaattaac caaaaaaggc tatgaggtta
     8581 ctgtgttgat gacgcaagca gctactgcct ttatcactcc gttgacccta caggtcttat
     8641 cgaaaaatcc tgtccatcta gatgtcatgg cagagcacga tgtcaaaatt gtcaatcata
     8701 ttgagctagc taaagcaaca gatctatttg tccttgctcc tgcaagtgcc aataccattg
     8761 ctcatttagc ctacggcttt gctgataata tggttaccag tgtcgcccta gccctgcctg
     8821 aggcaacacc caaactcatc gctcctgcta tgaatactaa catgtacctt aacccaatta
     8881 ctcagggaaa catcaaacgc ttagctgatc ttggctttcg agaaatacca cctaagacag
     8941 cactccttgc ctgcggcgac agaggacctg gggccttagc agatattgat gatatggtta
     9001 cagcaattag tcagcagcta gcaagatagc tggtcaccga ttagcaattg ctgtattata
     9061 atataaaaat ttaatggaga atgcaatgaa tcataacaaa tcttctgaaa tctctcgtat
     9121 tgccatcttt tttgcagtca tgctggttat tcacttcatt agtagctggt ttttttatat
     9181 ctggcctgtc ccaattaaac caacactcgt ccatattcca gttattgttg cttctatcat
     9241 gtatggtccg cgcactggag ctatcttagg aggcttgatg gggattgtca gtgtgatcac
     9301 aaataccttg gttttacttc caacaagcca tcttttctca ccatttgtca caaatggtaa
     9361 tctggcttcc ttgatgatcg ctatgctgcc tcgtatcctg attgggatca ctccttatta
     9421 ctgttataag cttatcaaaa acgagcttgg gcttgtccta gctggtcttg ttggctcgct
     9481 gacaaacacc atttttgttc tctcaggaat atttatcttt ttcccaacag cctctggtga
     9541 caatgtcaaa acgtttctaa ctaccattgt atctggcaat gctattactg aaatgattgt
     9601 ttcagctatc gttaccatta ctcttatccc agctttatcc aagctcaaaa aatcataata
     9661 ttgctcaagc tatgaagcat gctgtctgat aaggatagca tgctttaatg atatgtgaca
     9721 agcaaggaaa ttgatcctta tgtgaaaaaa tgattggaag ctattacaga aaataagtga
     9781 tttttccttt tcaacatgat ataatcccga ctttatcact taaaaacaag taaagaccag
     9841 ctaacccctt gtgtcccaag ggattttgct ggtctttaaa tttattttag tgttgtatat
     9901 ggatttttag cgtaatgttt gagctcttca aacttaacga ttcccttcgc ccattcaatt
     9961 cctagcagtc tgtttaactc
//
LOCUS       DARYNN010000065         9235 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.065, whole genome shotgun sequence.
ACCESSION   DARYNN010000065 DARYNN010000000
VERSION     DARYNN010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9235)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9235)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9235
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.065"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(380..2554)
                     /gene="nrdE"
                     /locus_tag="TVB59_001764"
     CDS             complement(380..2554)
                     /gene="nrdE"
                     /locus_tag="TVB59_001764"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEL1010624.1"
                     /translation="MSQKESYLSLNALTRFKRADGTYHFDSDKEAVQRYLEEHVYPQS
                     LSFDSLEEKWRYLVAHDYYDQEILKAYSAECITEAFTYAYQQKFSFLSLMGAMKFYQS
                     YALKTLDGSQYLEHFEDRAVMNALFLANGDPDLVRDLIDQILSGRFQPATPTFLNAGK
                     KRRGEYISCYLLRIEDNMESISRAIGTSLQLSKRGGGVALCLTNLREVGSPIKGIENQ
                     ATGIVPVMKLLEDSFSYANQLGQRQGAGAVYLNVHHPEILTFLDTKRENADEKIRIKS
                     LALGVVIPDITFQLARENKDMALFSPYDIKRVYGKDMSDIAITEEYDRLVANPAIKKT
                     YISARKLFQLIAELHFESGYPYLLFDDTVNKRNPHPQKGRIVMSNLCSEIAQVSTAST
                     FEEDLTFKQIGEDICCNLGSINIAEAMKHAVGFEQLIATSVRALDHVSRASDVSCAPS
                     VEKGNAANHAVGLGAMNLHGFLATNHIFYDSAEAVDFTDLFFHTMAYYAFKASSQLAK
                     EKGAFAGFEQSTYADGSYFARYLTKEAKPKTAKVAALLERYGLRVPSVADWQELVATI
                     QETGLANAHLMAVAPTGSISYLSSCTPSLQPVVAPVEVRKEGHLGRIYVPAYQISDDN
                     YAYYERGAYEVGPEPIINIVAAAQKHVDQAISLTLFMTDQATTRDLNRAYIHAFKLKC
                     ASIYYVRVRQDVLEGSEQYEEDTIVALTDTNASGEACQSCML"
     gene            complement(2601..3008)
                     /gene="nrdI"
                     /locus_tag="TVB59_001765"
     CDS             complement(2601..3008)
                     /gene="nrdI"
                     /locus_tag="TVB59_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEL1010625.1"
                     /translation="MAARVMLVYFSSRSNNTHRFVQKLDVRALRIPVTGEPLLVDEDY
                     ILIVPTYAAGGSDSKGAVPKQVIHFLNKANNRRHCKGVISSGNTNFGDTFAIAGPIIA
                     QKLQVPLLHQFELLGTQRDVIKVQAILAGDEAL"
     gene            complement(3010..4023)
                     /gene="nrdF"
                     /locus_tag="TVB59_001766"
     CDS             complement(3010..4023)
                     /gene="nrdF"
                     /locus_tag="TVB59_001766"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEL1010626.1"
                     /translation="MTQYYYDRSQSPIDYALSQTKKSLRSVNWNQLNDDKDLEVWNRV
                     TQNFWLPEKVPVSNDLNSWRSLGEDWQRLITRTYTGLTLLDTVQATVGDVAQIQHSLT
                     DHEQVIYTNFAFMVAIHARSYGTIFSTLCSSQQIEEAHDWVVSTESLQERARVLIPYY
                     TGDDPLKSKVAAAMMPGFLLYGGFYLPFYLSARGKMPNTSDIIRLILRDKVIHNYYSG
                     YKYQQKVAALSPEKQAEMKAFVFDLLYQLIDLEKAYLRELYDGFDLADDAIRFSVYNA
                     GKFLQNLGYDSPFTEEETRISPEVFAQLSARADENHDFFSGNGSSYVMGVTEETIDDD
                     WEF"
     gene            complement(4704..6707)
                     /gene="metG"
                     /locus_tag="TVB59_001767"
     CDS             complement(4704..6707)
                     /gene="metG"
                     /locus_tag="TVB59_001767"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003006062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEL1010627.1"
                     /translation="MTKKKPFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRMLGYD
                     VFYLTGLDEHGQKIQDKAQEAGLSPQAYVDGMAEEVKALWKLLDISYDKFIRTTGDYH
                     EEVVAAVFERLLAQDDIYLGTYSGWYSVSDEEFFTESQLAEVYRDEAGKVIGGVAPSG
                     HEVEWVSEESYFLRLSKYADRLVAFFKAQPDFIQPDGRMNEMLKNFIEPGLEDLAVSR
                     TTFTWGVPVPSNPKHVVYVWIDALLNYATALGYGQKDHANFDKFWSGRVFHMVGKDIL
                     RFHSIYWPILLMMLDLPMPERLIAHGWFVMKDGKMSKSKGNVIYPEMLVERFGLDPLR
                     YYLMRSLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVAMINKYFDGRVPAYVRNV
                     TAFDADLEQVVADHISEYHKQMEAVDYPRALEAVWTIISRTNKYIDETAPWVLAKAAD
                     SKEQLASVMAHLAASLRVVAHLIQPFMMTTSAAIMEQLGLGAKYHLEELDLADLPTGV
                     TVVAKGEPIFPRLDMEAEIDYIKEQMTMSIAKPQEADWDPEKVALKSEKDTITFEAFD
                     AVEIRVAEVKEVSRVEGSEKLLRFRLDAGDGSDRQILSGIAAYYPNEQELVGKKVQIV
                     ANLKPRKMMKKYISQGMLLSAEHDGKLTVLTVDPAVPNGTIIG"
     gene            complement(6925..7623)
                     /locus_tag="TVB59_001768"
     CDS             complement(6925..7623)
                     /locus_tag="TVB59_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEL1010628.1"
                     /translation="MSKRKRKTYQVYEGLRCAMMLCFISGYVNAFTYMTQGRRFAGVQ
                     TGNLLSFAIRLSERQFDQALQFLLPIIVFMIGQAFTYFMHCWANKHGLHWYLLSSFIL
                     TLIALVTAILTPLLSSFFTVSALAFFASIQVDTFKTLRGASYANVMMTGNIKNAAYLL
                     TKGLYENNKELVHIGRNTLIIILSFALGVVCSTLLSLSYGEYALSPMLIPLCYVNYLL
                     AQEFYHHQVSLKND"
     gene            complement(8009..9030)
                     /locus_tag="TVB59_001769"
                     /pseudo
     CDS             complement(8009..9030)
                     /locus_tag="TVB59_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515161.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
BASE COUNT         2720 a         2171 c         1798 g         2546 t
ORIGIN      
        1 aatattttag aaatactata ggttattttg aatcttctga ttgttttgac agttacaaga
       61 aatcccagtg attaacacgg agacaagccc cagtaattat cgattgaaga gggagctttt
      121 ttcttgattc tccttaagca aatcagcaag cattggctta tccaagccaa atgtccttac
      181 aacaagcacc ggtagcccac ttcatttgac aaggggcttg tcagcaagca ttgatcacaa
      241 atcaggctga gctgcattaa gctcaagaga gcttgccatc agcctgttgg atcaagcgat
      301 actataagcc tattaacaaa ctggctagac agagcatgaa ggctgattgg tgctgcctat
      361 ttttaaggct aaaaaagatc taaagcatgc aggattggca tgcctcgcct gaagcattgg
      421 tatcggtaag cgctacaatc gtatcttcct catactgctc acttccttcc agaacgtcct
      481 gtctgacgcg aacataataa atggacgcac actttaactt aaaggcgtgt atataggcac
      541 ggttgagatc acgtgttgtt gcttggtctg tcataaatag ggttaaggaa attgcctgat
      601 caacgtgctt ttgagccgct gctacgatat taataatagg ctcaggccca acctcatagg
      661 caccacgctc gtaataagca tagttatcat cgcttatctg ataagcaggc acataaatcc
      721 ttcctaagtg cccctccttt cgcacctcaa ctggtgcaac aacaggctgt aagctcggcg
      781 tacatgagga caagtagctg atcgagccgg ttggtgcaac tgccatcaag tgagcattgg
      841 caaggcctgt ctcttgaatc gtcgcaacta attcctgcca atcagccaca ctaggcactc
      901 gaagcccgta gcgctcaagc aaggccgcaa ccttagctgt cttaggctta gcctcttttg
      961 tcaaatagcg ggcaaagtag ctgccatctg cataggttga ctgctcaaag ccagcaaatg
     1021 ctcccttttc cttagctaat tgactagaag ccttaaaggc ataataggcc attgtgtgga
     1081 aaaagagatc agtaaaatct actgcttcag ctgaatcata aaagatgtga ttggtcgcca
     1141 aaaagccatg taaattcatc gcgccaagac caacagcatg attagcagca ttcccctttt
     1201 caacagaagg agcgcagctg acgtctgagg cccttgacac atggtccaag gccctaacac
     1261 tagttgcaat caattgctca aagccaaccg catgcttcat ggcttcagca atattaatag
     1321 agccaaggtt acagcaaatg tcctcgccga tttgcttaaa ggtcaaatcc tcttcaaagg
     1381 tgcttgctgt gctgacctga gcgatttcag agcaaaggtt tgacatgaca atccgcccct
     1441 tttgtgggtg tggattgcgc ttattaaccg tatcatcaaa caagagataa gggtagccag
     1501 attcaaaatg aagctctgca ataagctgaa agagcttacg ggcactgata taggtctttt
     1561 taatggctgg gttggccact aggcggtcat actcctcggt aatggcaata tctgacatgt
     1621 ccttgccata aactcgctta atgtcatagg gagaaaatag cgccatgtcc ttattttccc
     1681 gcgccagctg aaaggtaata tcaggaatga caacgcctaa cgccagtgac ttgatacgga
     1741 ttttttcgtc tgcattttct ctcttcgtat ctaaaaaggt cagaatctct gggtgatgca
     1801 cattgaggta aaccgcacct gctccctgtc tttgccctag ctgattggca taggaaaagg
     1861 aatcctccag tagcttcatc actggcacaa tgcctgtcgc ttgattttca atgcctttta
     1921 tgggagagcc aacctctctt agattggtta aacacaaagc aacgccgccg cctcgttttg
     1981 agagctgcaa gctcgtacca atcgcacgcg aaatagattc catgttgtct tcgattcgca
     2041 gcaaataaca ggaaatatat tcgcctcgac gctttttacc tgcatttaaa aaggtagggg
     2101 tcgccggttg aaagcgcccg ctaagtatct gatcaatcaa atcccgcacc aaatcaggat
     2161 caccattagc caaaaacaag gcattcataa cagcacgatc ctcaaaatgc tctaggtatt
     2221 gtgacccatc tagggtttta agcgcatagg actggtaaaa tttcatggct cccattaagc
     2281 tcaaaaatga gaacttttgc tggtaagcgt aggtaaaggc ttcagtgata cattcagccg
     2341 aataagcctt taaaatctct tgatcataat aatcatgcgc caccaaataa cgccatttct
     2401 cctccaaact atcaaaggat aggctttgtg ggtagacatg ctcctctaaa tagcgctgaa
     2461 cagcttcctt atcactgtca aagtgatagg taccatctgc tcgtttaaag cgtgtaaggg
     2521 catttaatga gaggtaggac tctttttgtg acattctttt ttcctttcgt tacaatgtgt
     2581 gatcgttttt ctatcattag ttataaggct tcatcacctg ctaaaatagc ctgcaccttg
     2641 atgacatctc tttgtgtccc cagcaattca aattggtgca aaagcggcac ctgcaatttt
     2701 tgtgcaatga ttggtcctgc aatggcaaag gtatcaccaa agttagtatt gccagaggaa
     2761 ataaccccct tacagtgcct tcgattgtta gccttgttta gaaaatgaat cacctgcttg
     2821 ggaacagctc ccttgctgtc tgagccacca gcagcatagg tagggacaat caaaatataa
     2881 tcctcatcaa ctaatagagg ctcaccagtg actggaattc ttagagctct tacatctagc
     2941 ttttgcacaa agcggtgagt gttgttagat cgcgatgaaa aataaacaag cattaccctt
     3001 gcagccatct taaaactccc aatcatcatc aatggtttcc tcagtaactc ccatcacgta
     3061 agaagagcca tttcctgaga aaaagtcatg gttctcatct gctcgcgctg atagctgagc
     3121 aaatacctca ggggaaatac gtgtttcctc ctcagtaaag ggagaatcat accctagatt
     3181 ttgcaaaaat tttccagcat tatagacgct aaagcgaatc gcatcgtcag caagatcaaa
     3241 gccgtcatac aattccctca ggtaagcctt ctccaaatca atcagctgat aaagcagatc
     3301 aaacacaaag gccttcatct cagcctgctt ttcaggactt agggctgcca ccttttgttg
     3361 atacttgtag ccactgtaat aattgtgaat gaccttatct ctcaggatta agcgaataat
     3421 atctgaggta ttgggcattt tgcctctagc tgacaggtaa aaaggcaggt aaaagccacc
     3481 atatagcaaa aatcctggca tcatagctgc tgcgacctta gacttcagag ggtcatcacc
     3541 agtataatac ggaatcaaca cacgcgctcg ctcctgtaag ctctctgttg acaccaccca
     3601 atcgtgggcc tcctcgatct gctgactgct gcacagggtc gaaaagattg tcccatagga
     3661 cctagcgtga atagcaacca taaaggcaaa attagtataa atcacctgct catgatcggt
     3721 caaagaatgt tgaatttgtg ccacatctcc aactgttgct tgaaccgtat ctagcaaggt
     3781 caagccggta taggttcttg tgatgagcct ttgccaatcc tcccccaaag aacgccaaga
     3841 attaaggtca ttagaaacag gaaccttctc aggcagccaa aaattttgcg tcacacggtt
     3901 ccagacctcc aggtccttgt cgtcattaag ctgattccaa ttgacagagc gcaaactttt
     3961 tttggtttga gacaaggcat agtcaatggg tgactgtgat cggtcgtaat aatattgggt
     4021 catgttttct ccttcaagct tgatagtcgc aatatcaatc cttcagctgc caagccttct
     4081 acagctttag gactagggaa gactgctaag tgccacattt agacaacaca aaaagacttg
     4141 ctctaaaggg caatcctaca ggctaatgat aatttcttgc tgatgatccc taaccagtca
     4201 gcaactgctt tgtaagcaag gctaagcccg cttttttccc cggctgaatt aagtatactt
     4261 aattcttatg tttgttataa taacacaata tatagtgctt tgcaatcttt ttgatacaat
     4321 atatagatta atttatgaaa aagaaatcat aaaaggagct agcagcacct taacgaaagc
     4381 cctgtctgta tgctcaccaa tccctcatct gccaacttgc ttttcaaata agatcaatac
     4441 atatcaattc acacccccat gaagggagcg actagagcgt gagataaaga aacaaaaatg
     4501 atgtattttc aatactcaga gctttcactg ctgttattgc ctattaggct gctagactag
     4561 tgcttctttc ttgttcaaag tttacaaagc tcccacaaga agtctaggtc tcttgtcttt
     4621 ttaagacact aaaaatcccg tatgctcctg ctaatcaatc tattagcaag acccatacgg
     4681 gatattgtca tctaaaagcc caatcagcca ataatcgtac catttggcac tgccggatca
     4741 accgtcagca ctgtcagctt gccatcatgt tctgctgaca aaagcatgcc ctgactgata
     4801 tattttttca tcatttttcg cggcttgagg ttggcaacaa tttgcacctt cttgccaacg
     4861 agctcttgtt catttgggta ataggctgca atacctgata agatttgacg atcagagcca
     4921 tcacctgcat ctaatctaaa gcgcagcagt ttttcagagc cttcaactcg tgacacctct
     4981 ttgacctctg ccacacgaat ctcaactgca tcaaaagcct caaaagtaat cgtgtccttt
     5041 tcagacttaa gggctacctt ttcaggatcc cagtctgctt cttgtggctt agctatgctc
     5101 attgtcattt gctctttgat atagtcaatc tctgcttcca tatcaagacg agggaagatt
     5161 ggctctcctt tggcaacaac cgtcacacct gtcggaagat ctgctaaatc aagctcttcc
     5221 agatgatatt tggcaccgag acctagctgc tccataatag cagctgaggt tgtcatcata
     5281 aatggctgaa tcaaatgagc caccacgcgc agacttgcag ctaaatgtgc catcacactg
     5341 gctagctgct ccttactatc agctgctttg gcaagcaccc aaggagcagt ttcatcaatg
     5401 tatttgttcg tgcgtgaaat aatcgtccat acggcctcca aggcacgtgg gtaatcaaca
     5461 gcctccattt gcttgtggta ttcggaaata tgatcagcca caacctgctc cagatccgca
     5521 tcaaaagctg taacgtttct gacataagca ggaaccctgc cgtcaaagta tttattaatc
     5581 atggcaactg tacgattcaa aaggttacca aggtcattag ccagctcata attgatacga
     5641 ccaacataat cctctggggt aaaggtacca tcagagccaa ccggcaagga acgcatgagg
     5701 taataacgca gaggatcaag accaaagcgc tcaaccagca tttcaggata gatcacattc
     5761 ccctttgatt tagacatttt accgtccttc atgacaaacc agccatgagc aatcaaacgc
     5821 tctggcattg gtaaatcaag catcatcaac aaaattggcc aataaatgct gtggaaacgc
     5881 aaaatatcct taccaaccat atggaaaacc ctaccactcc agaacttatc gaagttagca
     5941 tgatccttct gaccgtagcc tagtgctgtt gcatagttta agagagcatc gatccagaca
     6001 taaacaacgt gtttaggatt tgacggcaca gggacccccc aggtaaaggt tgttcggcta
     6061 accgctagat cctccagacc tggctcgatg aagtttttaa gcatttcatt catacgaccg
     6121 tccggctgaa taaaatcagg ctgagcctta aagaaggcaa ccaatctatc cgcatacttg
     6181 ctcaggcgca aaaaataaga ttcttcagag acccattcga cctcatgccc tgatggtgcc
     6241 acaccaccaa tgaccttgcc agcttcatcg cgataaacct cagctaactg actttctgta
     6301 aaaaattcct catctgaaac agaataccag cctgaatagg tccctaaata aatatcatcc
     6361 tgcgccagca acctctcaaa tacagcagca accacctcct catgatagtc gccagtggtg
     6421 cggataaact tatcataaga gatatcaagg agcttccata gtgccttgac ttcctcagcc
     6481 atgccatcaa cataagcttg aggggataag ccggcttctt gtgccttatc ctgaatcttt
     6541 tgaccatgct catcaagacc agtcaaataa aaaacgtcat aacccaacat acgcttatag
     6601 cgagcaagaa catcacaggc aatcgtagta taggcagagc caatatgaag cttccctgac
     6661 gggtagtaaa tcggtgttgt aatataaaat ggttttttct tagtcatctt acgtcctttc
     6721 aaggctaatg aaacctttgt aatcagggac tagggcaata cccattccca agctgagtcc
     6781 tgtcagctat caactgacat tataccataa ttttagcata aaaaaatgat cactcagcct
     6841 attaactgat acctccccca taatagacaa tgacaaacaa gcagtcatca aaaattatag
     6901 gaggaggata tcaattagta gacttcaatc atttttcaat gatacctgat gatggtaaaa
     6961 ttcctgtgcc aagaggtagt tcacgtagca caatgggatc agcatgggag ataaggcata
     7021 ctcaccatag gatagtgata aaagagtaga acagaccact ccaagggcaa aggagaggat
     7081 aataatcaag gtattgcgac caatatggac tagctctttg ttgttctcat atagtccctt
     7141 tgtcaatagg taggcagcat ttttaatatt accagtcatc atcacattgg catagctcgc
     7201 accgcgcaag gttttaaagg tatctacctg aatcgaagca aaaaaagcta gagctgaaac
     7261 cgtaaaaaat gacgacaata agggtgtgag gattgctgtc acaagagcaa tcagggtcaa
     7321 gataaagcta gacaaaaggt accaatgcag accatgctta ttggcccagc agtgcataaa
     7381 gtaggtaaag gcctgcccaa tcataaaaac aatgataggc aataaaaatt gcagggcttg
     7441 gtcaaactgg cgctcagaca gacgaatcgc aaaggataag agattgcctg tctgaacccc
     7501 tgcaaagcgc ctgccttgcg tcatgtaggt aaaggcattg acataaccac tgataaagca
     7561 aagcatcatg gcgcacctta agccctcata tacctgatac gtttttcgtt tcctctttga
     7621 catacttgcc ttccttaatg tgattccaaa agaaaaatac tgacaaacag tatttgatgt
     7681 gattattagg aggataagct aagctcaatt gcccttgatc acagatagtc accaaagcaa
     7741 gttctgcagc tagactcggt aagtccccca aatacagctt tagtatagca taggcagtct
     7801 cttttatcaa gatgctttgc aggatcaact agcaccataa gactaaccat tagccaaaaa
     7861 gtactcaccc tctatgagga ccagcaggta aacctgataa aaaaactaaa aagccaccat
     7921 ttctgatgac ttcttagtcg gcctcttcaa caacttgtag cttacacaag ctatagcgct
     7981 aaggacagcc tttcattgga gcacaacatt agtcttcctt gcgttttgtt gacacaacaa
     8041 ccacacctgc acttgccatc actgcaagag ctgccgctgt gaagaatgga tgtgtcgctt
     8101 cacctgttga tggaagcttc ttagcttctt gcttaggtgc tggtttcttc tcttccttct
     8161 tagcttcagg ttttggttct ggcttaggct caggttttgg ttctggttta ggctcaggtt
     8221 taacctcttc atacacataa accacacgaa gatcgccttc tagggttgta ccagtttcgc
     8281 taggtgagcc ctcttgaagc ttcttgaact tgtagacctt accatctttt tcaatcttat
     8341 caagacgaag tgaggtagta tcgtacgctt cacccggcaa gccttgtgat accgcaacag
     8401 tttcacctaa aacattacct tctgtatcca cataagatac aagaacatta gcattaaacg
     8461 gaacaaattc ccaatcacca attaaagtaa tatctccatc acctggtgct gtatagccct
     8521 ctgtaagttt agtttcacca tcatttgtgt aacgtgacca accagtaaat ctccactcac
     8581 cagttgcagt tctgacattt tagcaacatc aagaagctcc tgtggtaaag tcataccttg
     8641 cttgctaccg aaaatgtaga taactgtact cttctcttta cgaagagctt cattagctgc
     8701 ttcttcttcg gcacgttttg atctttctgc ttctgcctta accgctatag tttgttcagc
     8761 ctcagctaag attttgttaa tatcgtcaac ttgaattaaa tttgaatcgt taattttcga
     8821 ttcaaaacct gcgattgttg aagccaattc cggatgctgt tgtttaagag tagttagacg
     8881 agctgtagcc tcagctttag ttgcatactt ctgccctctc attgttacct gtgccgatac
     8941 agaagctgta ccaactaaca aggtgcagaa tactgaagct agtccgaaag ccgacttacg
     9001 aagatagtac ttcatttctt tttttgccat ttttattccc ctttaaatat aatggacata
     9061 atgtctccta attatcaatg acagataatt acacttttat tataaaaggt attttctgtt
     9121 tagtcaagag aaaactgttt cttttacatt tctgttattt tacagttata tgtcacatct
     9181 gatttggttt aatttttctg aaaaaccagt agataaggca ttttaagcat ttttt
//
LOCUS       DARYNN010000066         9170 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.066, whole genome shotgun sequence.
ACCESSION   DARYNN010000066 DARYNN010000000
VERSION     DARYNN010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9170)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9170)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9170
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.066"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            101..1027
                     /locus_tag="TVB59_001770"
     CDS             101..1027
                     /locus_tag="TVB59_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEL1010629.1"
                     /translation="MEKIIITATAESIDQVKSLLAAGVDRIYVGEADYGLRLPHAFSY
                     DDLRQIAALVHKAGKELTVACNALMHQGMMDRIKPFLDLMKEIAVDYLVVGDAGVFYV
                     NKRDGYDFKLIYDTSVFVTSSRQVNFWGQHGAVESVLAREIPSEELFALADNLDYPAE
                     ILVYGASVIHHSKRPLLENYYHFTKIDDEVSRERGLFLAEPGDPDSHYSIYEDNHGTH
                     IFINNDIDMMTKLGELYEHGLTHWKLDGVYCPGENFVAITKLFIKAKALLESGQFTTE
                     LAQQLDAEVQGLHPVGRGLDTGFYDFDPKTVK"
     gene            1135..2421
                     /locus_tag="TVB59_001771"
     CDS             1135..2421
                     /locus_tag="TVB59_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEL1010630.1"
                     /translation="MSNVKKRPEVLSPAGTLEKLKVAIDYGADAVFVGGQAYGLRSRA
                     GNFSMEELQEGIDYAHKYGAKVYVAANMVTHEGNELGAGEWFRQLRDMGLDAVIVSDP
                     ALIVICSTEAPGLEIHLSTQASSTNYETFEFWKELGLTRVVLAREVNMAELAEIRKRT
                     EVEIEAFVHGAMCISYSGRCVLSNHMSHRDANRGGCSQSCRWKYDLYDMPFGSERRSL
                     KGEIPEEYSMSSVDMCMLEHIPDLIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     MESPEAFYAIKDDLIDELWKVAQRELATGFYYHIPTENEQLFGARRKIPQYKFVGEVV
                     SFDDDSMTATIRQRNVIVEGDRVEFYGPGFRHFETVIKDLHDADGNKIDRAPNPMELL
                     TISLPQAVKPGDMIRACKEGLVNLYQKDGTSKTIRA"
     gene            complement(2517..2842)
                     /locus_tag="TVB59_001772"
                     /pseudo
     CDS             complement(2517..2842)
                     /locus_tag="TVB59_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677676.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2977..3189
                     /locus_tag="TVB59_001773"
     CDS             2977..3189
                     /locus_tag="TVB59_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEL1010631.1"
                     /translation="MSEFTFKIEEHLLTLSESDKGWTKELNRVSFNGAEPKWDIRTWS
                     PDHTKMGKGITLTNEEFKTILDAFRR"
     gene            complement(4085..4225)
                     /locus_tag="TVB59_001774"
     CDS             complement(4085..4225)
                     /locus_tag="TVB59_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010632.1"
                     /translation="MKKEYISYLSAAIFILYALLSLKWIFFVLGVILLIIGLADRFRS
                     KP"
     gene            complement(4588..6081)
                     /gene="lysS"
                     /locus_tag="TVB59_001775"
     CDS             complement(4588..6081)
                     /gene="lysS"
                     /locus_tag="TVB59_001775"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEL1010633.1"
                     /translation="MSNQHIEELNDQQIVRREKMAALAEQGIDPFGKRFDRTTNSGEL
                     KEKYSDKTKEDLQELQATAIIAGRLMTKRGKGKVGFAHLQDRQGQIQIYVRKDSVGDD
                     NYDIFKKADLGDFIGVEGDIMCTDMGELSIKATKLTHLSKSLRPLPEKFHGLTDIETI
                     YRKRHLDLISNRSSFERFITRSKMISEIRRYLDGLGFLEVETPVLHNEAGGAAARPFI
                     THHNAQDIDMVLRIAPELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYE
                     AYADYLDMMTLTEGIIQHAAKAVKGEGPIDYQGTEIKLHEPFRRVHMVDAIKEVTGID
                     FWPEMTFEEATALANEKHVPVEKHFTSVGHIINAFFEAFVEDTLIQPTFVYGHPVEVS
                     PLAKKNPEDSRFTDRFELFIMTKEYANAFTELNDPIDQLSRFKAQAAAKELGDDEATG
                     IDYDFVEALEYGMPPTGGLGIGIDRLCMLLTNTTTIRDVLLFPTMKP"
     gene            6424..7901
                     /locus_tag="TVB59_001776"
                     /pseudo
     CDS             6424..7901
                     /locus_tag="TVB59_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677680.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
     gene            8213..9118
                     /locus_tag="TVB59_001777"
     CDS             8213..9118
                     /locus_tag="TVB59_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEL1010634.1"
                     /translation="MISAIVFDVDDTIYDQQAPYRIAMEKCFPDFDMSLINRAYIRFR
                     HYSDVGFPRVMSGEWTTEYFRFWRCRETLLEFGYRDIDQATGVHFQEVYEHELQHITM
                     LDEMRMTLDFLKSKNVPMGIITNGPTEHQLRKVRKLGLYDYVDPKRVIVSQATGFQKP
                     EKEIFNLAAEQFDMNPATTLYVGDSYDNDVMGAKNGGWHAMWFNHRGRSLKPGTRPIY
                     DVAIDNFEQLFGAVKVLFDLPDNKVIFDINDKKNPVLQLGLNNGLMMAAERLLESNMS
                     IDKVVILLRLNKQQERVLRMKYANR"
BASE COUNT         2533 a         1730 c         2097 g         2810 t
ORIGIN      
        1 ttttttttga aggcttctcg ttataggcct tggtataggc gttaagattt tgaatgaatc
       61 atttttgaaa gcctaagaaa tttggtataa tatcccttgt atggaaaaaa taattattac
      121 agccacagca gaaagcattg accaagtcaa atcgctttta gctgcaggtg ttgatcgtat
      181 ttatgtaggc gaagctgatt atggcttgcg tcttcctcat gctttttctt atgatgactt
      241 gaggcagatt gcagcgcttg ttcacaaggc gggcaaggag ctaacagttg cttgtaacgc
      301 tctgatgcat cagggcatga tggatcgtat aaagcccttt ttggacctta tgaaggagat
      361 tgctgtcgat taccttgttg ttggtgatgc cggtgttttt tatgtgaata aacgagatgg
      421 ctacgacttt aagctgattt atgatacttc ggtttttgtt acctcaagcc gtcaggttaa
      481 tttttggggg cagcatggcg ctgttgaaag tgttttagct agagagattc cctcggagga
      541 attatttgcc ttggctgaca atcttgacta cccagcagaa atattggttt acggggcctc
      601 tgttattcat cattctaaga gaccgctcct tgaaaattat tatcatttta ccaaaattga
      661 tgacgaggtc agtcgagagc gtgggctttt cttagcagag ccaggcgatc ctgatagtca
      721 ttattctatc tatgaggaca atcatggaac tcatattttt attaacaatg acattgatat
      781 gatgactaag ctaggcgagc tatatgagca tggcctgaca cattggaagc tagatggtgt
      841 ttactgtcct ggtgagaatt ttgtggccat taccaagctg tttataaaag caaaggcttt
      901 gctggagtct gggcaattta ccacagagct agctcagcag cttgatgcag aagtgcaagg
      961 gcttcaccct gtagggcgtg gtctggatac aggcttttat gattttgatc ctaaaacagt
     1021 caaataagct ataacttgac ttgtcctgat taaggttact atttcaaggc atgacaagtt
     1081 aatcattcaa agatgttaca tcttacctat cttgaaaata gaaagaataa caacatgtca
     1141 aatgtaaaaa aacgtcctga ggtgctgtcg cccgcaggaa cacttgaaaa attaaaggtt
     1201 gccattgatt atggcgctga tgcggttttt gttggtggac aggcctacgg gctaagaagt
     1261 cgcgcaggaa acttctctat ggaggaatta caagagggga ttgactatgc tcacaagtat
     1321 ggggctaagg tctatgttgc tgccaatatg gttacccatg agggcaacga gcttggggct
     1381 ggtgagtggt tccgtcaatt gcgtgatatg gggcttgatg cggtcatcgt ttcagacccg
     1441 gcccttattg tgatctgctc aacagaagca ccaggacttg agattcatct atcaactcaa
     1501 gcatcatcaa cgaactatga aacctttgaa ttttggaagg aattaggcct aacgcgtgtc
     1561 gtgctagcac gtgaggtcaa tatggcagaa ttggctgaga ttcgaaagcg cacagaggtt
     1621 gagattgagg cctttgtaca tggtgccatg tgtatttcct attcagggcg ctgtgttctc
     1681 tctaatcaca tgagtcaccg agatgccaat cgcggaggct gctcacaatc ctgccgctgg
     1741 aagtatgatt tgtatgatat gccttttggc tcagagcgtc gttccttaaa aggagagatt
     1801 ccagaggaat actccatgtc ctcggttgac atgtgcatgc tggagcatat ccctgatttg
     1861 attgaaaatg gagttgatag cttgaaaatc gaagggcgca tgaagtctat ccattatgtg
     1921 tcaacagtga ccaattgcta taaagcagct gttgatgctt atatggaaag tccagaggca
     1981 ttttatgcta ttaaggacga ccttattgat gagctttgga aagtggctca gcgtgagcta
     2041 gcaactggct tttactacca tattccaact gagaatgaac agcttttcgg tgcgcggcgt
     2101 aagattccgc aatacaaatt tgttggggag gtggtttcct ttgatgatga cagcatgaca
     2161 gccactattc gccaacgtaa cgtcattgtt gaaggagaca gggttgagtt ttacggaccg
     2221 ggcttccgtc attttgaaac agtgatcaag gatttacatg acgctgacgg caataaaatt
     2281 gaccgtgcgc caaacccaat ggagctctta accatctcct tgccacaggc tgtcaagcca
     2341 ggagatatga ttagggcctg taaagaagga cttgttaacc tctatcaaaa ggacggaacc
     2401 agtaagacca taagagccta gcaccactag actaagcaat aggatttgac caattacttt
     2461 tgacacagag aagtgataag gttaggtctc ctttactcct gattagggta ctgagtctat
     2521 ggcttttctt tggtgctggt gcgtgtatga ggtactaagc tagccttatc aatatctgct
     2581 aaaaaaataa tgcagtcagg ttttgattgg tattttttaa gaccaattga ccggttagct
     2641 gatcgtattt tttaatgtgc ccagtgaagc ttttggcttg atagatcaca tgaattggaa
     2701 tctccttgac ctgtgcctct ttgatggtgg taatgatctg gttggccttg aggttaacgg
     2761 gagaagcctt ggcttttttg ggaggctgat tgtcaataaa gccgatcaag gctgattgca
     2821 gctgcttcat cattgatttc atagctattg tcctcaaaca ttgatagaat agtttgatag
     2881 tattttacct taaactatga tttttaaaaa gaatttactg ttttgcattc aatttttaat
     2941 attattttcg aatagataga tgaggaggaa aatataatgt cagaatttac atttaagatt
     3001 gaggagcatt tgctaaccct gtcagaaagc gataaggggt ggacaaaaga gctaaaccgc
     3061 gttagcttca atggagcaga gccaaaatgg gatatccgca cctggagccc tgatcacaca
     3121 aagatgggta agggcattac tctgaccaat gaagaattta agacaattct tgatgccttt
     3181 cgtcgttaag ccttagctta gtcatcaata acttcaatgt gagaagaacc ttttctaacg
     3241 aacagtatca accatcagtt actttgttct tgtaggaagg ttcttttgtt atctcttcaa
     3301 gtgagttttt aagagcaagg taaaagacta tcgtctagaa cccccttagc attcatagct
     3361 gctaccgcaa cgataaaagt taaaaaacaa actaactggg gatctggtat ctagaaagtt
     3421 aatctagtcc tcttagagct tttagtaact gttagtcact atttattggt gagaggaata
     3481 tatcacaatg ctccaatcga gccttggttt gggtgtttta agtccggatg ctatgagcta
     3541 aagtcatacc agacttgtga agagcctatc actgatagta atcgctatct ctacttttac
     3601 aatgatagtc atctttaaaa gcacatgaaa ggccctgccc ctcctttaag gaggaacaag
     3661 gcttctgttt aatcattatg agattagtat tcgcttaata ggaagtcact caagctcagc
     3721 gtctattttg agactgatgc ttctgtccta gccttaggct gctcatattc tgctctaaaa
     3781 tcatacggat tgtcctgatt tgctttagaa tagcatactt gttgagtcta ggtcccaagg
     3841 atcttgaatg actgacgttg aaggtgttta gctcctgtta tcttggtata agaaggtatg
     3901 accttttggt aattggattg tctattgtat ggttccaaga tgatgattgg catgcttggt
     3961 tgttgactgc aagctgatag ccttgtggga ggctttgctt tcataaggct taagggctat
     4021 ttttacttta atgtaaggct ccttggctgg cagctatcga gacttggaga tgatagaggg
     4081 ctagctaagg ctttgacctg aaacgatcgg ctagaccaat aatcaagagg atcaccccta
     4141 aaacaaagaa aatccatttc aagctgagta aggcataaag gataaaaata gcagctgaga
     4201 ggtaactaat gtattctttt ttcataagat gctccctatc tttttatact attgtagcat
     4261 aaaaatcagt ttaaatgctg atgaaatcaa tggctatttt ggctttcatt ggcctagtaa
     4321 aaaccgttta gcctagcagc atgtcatcat tgcaaacaaa aaagattgaa gaatcaagtc
     4381 taagagatga ttcttcaatc ctagtataca gacaagctaa ggacatcact tcaaaagtga
     4441 ggcttttaga gaagctaaag gcaactaatg actattagct aggcctagct atggaagtga
     4501 ttggtcatag tgatcattcg atctggataa gaggcttagg atcagctaga gaaagctgct
     4561 ttttaaacac tggtagctag tcgcttttta tggcttcatt gttgggaata acaaaacatc
     4621 gcgaatagtg gttgtatttg tcagcagcat gcagaggcgg tcaataccga ttccaagccc
     4681 gcctgttggt ggcataccgt attcaagagc ctcaacgaag tcgtagtcaa taccggttgc
     4741 ttcatcgtct ccaagctcct tggctgctgc ctgtgcctta aagcgtgaca gctgatcaat
     4801 tggatcattt agctcggtaa aggcattagc atattccttt gtcatgataa agagctcaaa
     4861 gcggtctgtg aagcgactgt cctcagggtt tttcttagca agcggtgaaa cctctacagg
     4921 gtgcccatag acaaaggttg gctgaattag ggtgtcctcg acaaatgcct caaagaaggc
     4981 attgatgata tgaccaacag aggtaaaatg cttttcaact ggcacatgct tttcgttagc
     5041 aagagctgtt gcttcctcaa aagtcatctc aggccagaag tcaataccag ttacctcctt
     5101 gatggcatca accatatgca cgcgtctgaa tggttcatga agcttgattt cagtcccctg
     5161 ataatcaatt ggtccctctc ccttgactgc tttagcagcg tgctgaatga ttccttcagt
     5221 tagagtcatc atatctaaat agtctgcata ggcttcatag acctcaatag aggtaaattc
     5281 tgggttatgt gtagcgtcca tcccttcatt acgaaagatc cgtccaattt catagacacg
     5341 ctccatgcca ccgacgatga ggcgcttgag atgcagctct ggtgcaatgc gaagcaccat
     5401 atcgatatct tgtgcattgt ggtgagtgat aaagggacga gcagcagcac caccagcttc
     5461 attatgaagg acaggtgtct ccacttctaa aaagccaagg ccatcgaggt aacgacgaat
     5521 ttcagaaatc atttttgaac gtgtgatgaa ccgttcaaag ctgctgcggt ttgaaatcaa
     5581 atccagatga cgcttgcgat aaatggtttc gatatcagtt aagccatgaa atttctctgg
     5641 tagcggacgt agagatttgg atagatgggt cagttttgtg gccttgatag acaactcacc
     5701 catatcagta cacataatgt cgccttcgac cccgataaaa tcaccaaggt cagctttttt
     5761 gaaaatgtca tagttgtcat caccaactga atccttacga acatagattt ggatttgccc
     5821 ttggcgatcc tgaagatgag caaagccgac ctttccttta ccacgcttgg tcatcagacg
     5881 accagcaata atcgcagtgg cttgaagctc ttgtaaatcc tctttggttt tgtctgagta
     5941 tttttccttt aattcaccag aattagttgt tcggtcgaag cgtttgccaa atggatcaat
     6001 gccttgctca gctaaggctg ccattttttc acgacggaca atttgttgat catttaattc
     6061 ttcgatgtgt tgatttgaca tgttttcctc caatactttt ccttcctatt gtaacataaa
     6121 agattataga atacacctat atttcgtggg aattctatca tcgaagcctc agatgatagg
     6181 cctttgactt gtatagataa attggttttg tctgagttgg tttttctgta taaataagct
     6241 attatttgtg agatcttact tgaattgaag gcttttgcta gttccaatag attatttttg
     6301 atgatatttg acaaaaaaac ttaaattgtg aaaaaatatt aatcgaaaaa atcaaaaaac
     6361 tctcaacgct aaggctagtc tttgtgcagt tgagggtttt tatcaggaaa ggatcataaa
     6421 gaaatggaaa cttatgatat acacgggaag ccttatcatc gaacgctgat gattatattg
     6481 ctgttggtgg gaacctttgc aggggtttta aaccaaacaa gcttggggac agctatacca
     6541 acattgatgg aaaattttaa ggtacctttg tcaacaactc agcaggcaac cacttggttt
     6601 ttgcttgcta atggcattat gatccctgtt tcggcctttt tagcaacgcg attttccact
     6661 aaaagactct acatgacagc ttatgctatt cttgtgagtg gcttgttact agcagctctg
     6721 gctccgactg ctcattgggg agttttttaa cagcacgtat cgttcaggct tgtgcagtgg
     6781 gcattaccat gcctttgatg caggtggtga tgatcaacgt ttttcctgca gagcagcgtg
     6841 gtgcagcaat gggaatcaat ggcttggtgg ttgggctagc tccggctgtt ggaccaacct
     6901 tgtcaggctg gattttgaaa aaggattttt cagtattagg catttattta ggctggcggg
     6961 ccatttttat cttgccttta gtgattttgc tgttggtttt aagcctgtcg cccttcatgc
     7021 tccgagatgt tatccctcag caggctgtta agcttgattc aacatctcta ggcttatcta
     7081 tcttagggct gggtgctttt ctctggggct ttacaaatgt tgcagcttat ggctggctag
     7141 atatggtgta cgtgatttta cctattttag tcggtattgg tggaatttac ctcttttcca
     7201 agcgtcagct acaattagag aagccctttt tagatattag agtctttcgc aacaagcaat
     7261 ttaccttgac aacaatagca attgccctaa cgatgatggc tatgatcggt gttgagatga
     7321 tgctgccgct gtatctgcaa aatgtcagag gcttatctcc attaaattcc ggaatggttt
     7381 tgttgccggg tgctttgatt atggggctga tcagtccagt ttctggccga atttatgaca
     7441 agatcggtgc tcgttatctg gcgctattag gctttaccat tttagctgcg gcgactctac
     7501 catttgtatt tctaaatgaa aatacctcac gctttttgat tactgttttg tatgccatta
     7561 gaatgtttgg catatcaatg attttaatgc ctttaactgc aagtgctatg aatgccttgc
     7621 catcgcatga atcggcgcat ggaacggcag ctaataatac tgtacgccag atctcctctt
     7681 ctattgttgt ggcggtgtta tcgagtgtga cacaaaacat tatcagcagc aaacagccgc
     7741 ctaaaatgct cctatccata caccctgagc aatacgctaa gaagcttcta gaagccaatt
     7801 taaatggctt tcatgcctct tttttccttg gctttatgtt tgcagtggta ggctttattg
     7861 ttgtgctttt cctacataag ggaaaggtta tcgagaaata gctcctgatt agtgtggtta
     7921 aaacaaatag gctaaaggcc tcacgccaaa cgcatgaaaa aacagctgtt tttgatagct
     7981 tttctgatta atgcactctt tttcaagaaa acttatggca caatgaagct aaatgtgagc
     8041 agttgatgat gtcaaaataa tggaaaatct attgaaaaat gtttgagtct agaaaattgt
     8101 tacctgcatt ttctttgtgt ctctagcatg ctaaaagcat gggctggttt gaaaagtcga
     8161 tgacaaaata gtataatgat aagcatatca acctagaaaa gaaaagagac tcatgatttc
     8221 tgcaattgtt tttgatgtag atgatacgat ttatgaccag caggcgcctt accgtatcgc
     8281 aatggaaaag tgctttccag attttgatat gtcattgatc aatcgagcct atattcgttt
     8341 tcgccattat tctgacgttg gatttccaag agtgatgtca ggtgagtgga cgacagaata
     8401 ttttcgattt tggcggtgtc gggagaccct gcttgagttt ggctatcgtg acattgatca
     8461 ggcgacagga gtgcattttc aagaggtcta tgagcatgag ctgcagcata ttaccatgct
     8521 tgatgagatg cgcatgacac ttgatttctt gaagtcaaaa aacgttccga tggggattat
     8581 cacaaatgga cctactgagc accagctaag gaaggtgcgt aagctagggc tatacgatta
     8641 tgttgatcct aagcgcgtga ttgtcagtca ggcgacaggc tttcaaaagc cagaaaaaga
     8701 gatattcaac ctagcagcag agcagtttga catgaaccct gcaacaaccc tctatgtcgg
     8761 cgactcttat gacaatgatg ttatgggagc taaaaatggt ggctggcatg ccatgtggtt
     8821 taaccacaga gggagaagtc taaagcctgg gacaaggcct atctatgatg tggccattga
     8881 taactttgag cagctgtttg gtgctgttaa ggtcttgttt gatctgccag acaacaaggt
     8941 tatttttgat atcaacgaca agaaaaaccc ggtgctgcaa ttaggactta acaatggttt
     9001 gatgatggca gcagagcgct tgctagaaag taacatgagt attgataagg ttgttatcct
     9061 gttacgcttg aataagcagc aagaaagagt gctgcgcatg aagtacgcta atagatagca
     9121 gttattgatt gaaaagcatg ctatgtttaa ttggcactcc aaaggctaga
//
LOCUS       DARYNN010000067         9020 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.067, whole genome shotgun sequence.
ACCESSION   DARYNN010000067 DARYNN010000000
VERSION     DARYNN010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9020)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9020)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9020
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.067"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            29..274
                     /locus_tag="TVB59_001778"
     CDS             29..274
                     /locus_tag="TVB59_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEL1010635.1"
                     /translation="MGIIWTLIVGALIGAIAGALTKKGGSMGWIANIAAGLIGSYVGQ
                     ALFGSWGLTLAGMALFPSIIGAVIVVIITSFVLNKSN"
     gene            322..903
                     /gene="amaP"
                     /locus_tag="TVB59_001779"
     CDS             322..903
                     /gene="amaP"
                     /locus_tag="TVB59_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEL1010636.1"
                     /translation="MSKFLKISYSLIGLVLLTVFGGVIAITGDYIRLPIGYQWLHWDM
                     NWLPKFLNPALYYYYFWAAIALFLITVLILLVIIFYPRTYTEIQLAKDKGTLLLKGSA
                     IEGYVAAAIKAAGLMSSPRVTAKLYKRKFKVNVSGQLASRVAVTEQLNGIKEGIETGL
                     TEFFGINRPVHFKVYVKDIADAKQKHSSKRRVE"
     gene            913..1101
                     /locus_tag="TVB59_001780"
     CDS             913..1101
                     /locus_tag="TVB59_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEL1010637.1"
                     /translation="MAFYERFKYPIIGGLIGLIAAVLLMTFGLFKTLLAIIFIILGVY
                     GGLYAKKTGIIDQLIKRN"
     gene            1114..1653
                     /locus_tag="TVB59_001781"
     CDS             1114..1653
                     /locus_tag="TVB59_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEL1010638.1"
                     /translation="MTETYIKNTTHKEPTSAVRGELTYDDKVIEKIVGLALENIDGLL
                     GVNGGFLANLKDKLVNSDSVRDGVNVEVGKKEVAVDLDIVAEYQKHVPTIFDAIKSVV
                     ENEVKRMTDLEVIEVNVKVVDIKTKEQFEADKVSLQDKVTEVARSTSEFTSKQVDNVK
                     ASVGAGVEKVQEQTEPRVK"
     gene            1691..1888
                     /locus_tag="TVB59_001782"
     CDS             1691..1888
                     /locus_tag="TVB59_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEL1010639.1"
                     /translation="MSEEKVNAKLEQAGGKIKEAFGKVTGDKSLETEGKVDQAASKIK
                     EVAADAKDAVKGFVKGLKQDK"
     gene            1898..2386
                     /locus_tag="TVB59_001783"
     CDS             1898..2386
                     /locus_tag="TVB59_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEL1010640.1"
                     /translation="MKAKDIKSTLTYDDKVIEKIVGHALEKVSGLLAVNGGFFSNIKN
                     NLVNSDSVRDGVSVEVGSKEVAVDLDIVVEYGKDIPAIVESIKAIVFQNVDSMTHLRV
                     VEVNVNVVDIRTKEEHEAASVTVQDRLTDAASATSQFVAEQADKVKETVSKTTDNNET
                     VE"
     gene            2542..3183
                     /locus_tag="TVB59_001784"
     CDS             2542..3183
                     /locus_tag="TVB59_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1010641.1"
                     /translation="MTSNKREITNSKYQKIAISVAERIANGEYEVGEKLKSRTTIAST
                     FKVSPETARKGLNILADLKILTLKHGSGAIVLSKEKAIDFLNQYESTHSIAVIKENIR
                     HNIREQEKAMEHLTVLVNEFLMQSQSISKQYPLAPYEIICSQDSEHFGQSIGDLNIWH
                     QTGATIVAIEHDGQFIVSPGPYAVIEKGDHIYFVGNEDVISRMKTFFNVRKGL"
     gene            complement(3300..3848)
                     /locus_tag="TVB59_001785"
     CDS             complement(3300..3848)
                     /locus_tag="TVB59_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEL1010642.1"
                     /translation="MTTRHTPTKAYLKQALVSLLTEKSFETITVSDLTKKAGVNRGTF
                     YLHYRDKHDMMTHLINDTLDDLYQLLNDPHIFTDTRLVLKEALAYIIDNLPFIAAMAN
                     SSYLNFSQILKDFIYQFLTTIDGFQEIITKHYQIPYHYALEVYLASIESLISYWISHD
                     CQETTDDMTAIILKTVGFEKVI"
     gene            3971..4672
                     /locus_tag="TVB59_001786"
     CDS             3971..4672
                     /locus_tag="TVB59_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1010643.1"
                     /translation="MSYIEMRSSSKTYQIGETTVKANDEVSFEIERGELVIILGASGA
                     GKSTVLNILGGMDSNDQGQVIIDGKDISTYSKKALTSYRRYEVGFVFQFYNLVPNLTA
                     KENVELAADIVADALDPTTVLNEVGLGGRLEHFPAQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDYQTGKQILRLLQDMAHDKGRTVIVVTHNTALAPIADRVIYMHDGRVTK
                     TVLNKQPLDIDRITY"
     gene            4684..7323
                     /locus_tag="TVB59_001787"
     CDS             4684..7323
                     /locus_tag="TVB59_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEL1010644.1"
                     /translation="MKQKTLWKDSFRAIKASKGRFLSLLFLMALGSFALVGLKVAGPN
                     MEKTASHYLEEHQVMDLSILASHGFSDRDKQELASLKNARLEYASFVDGAFDHQRKAI
                     RLYSMPQSLSQASLVKGDYPSKASDILLSEALSSRYRLGQIITISLKTKGLLKHRSYR
                     VVGFAHSPEIWSKTNLGVSSAGDGNLYAYAYLHPSAFQQGHNLLRIRYDDLRGLNAFS
                     TQYNERLLQHQAELDQILQDNGQERYEEMLNDLNRSLKDSKVKLEEQRTVLKASEDQL
                     ALLSGHALEQAQTQLKQGQEELAKKEASLLELAEKQRAAMIKPTYTSYSRSTLPGGEG
                     YQTYATSTQSISHVGNIFPVVLYLVAALVTFTTMARYVDEERTNSGLLKAIGYSDWDI
                     TKKFLLYGALAALLGTGLGVLGGTYFLSRLISAILTDALTIGSTQLYFYWSYSVVAVL
                     LALLSAVLTAYMVVRRELFLRPSQLLLPKPPSSGARIWLEHVSFIWRRLSFTYKVTFR
                     NIFRYKQRMLMTVIGVAGSVALLFSGLGIQSSLANSLSYQFGKLTAYDMLVVEAPTAE
                     AHDRQELAQYLKADQIASKKEIYYANLSLKIKDLDNKQTVSLISSDQSTLSPYFSLIG
                     AADRKKLDLPSTGVLISKKLADYYQAHAGDQLELEASNGKRYQLRVSQVIDMTVGHYL
                     FMSKSYYQQVFRDMEASPSYLVTTAKASPSAVKDVASQLLAMPAVQAVSQHSSIVATV
                     TGIVASLDQVMTLLVLLSVLLALVILYHLTNINIAERVRELSTIRVLGFYDKEVTLYI
                     YRETMLLSAVGILIGLWGGSYLHAYIMKVIANDSMSFGRTVDAYVYLVPVGAIVLLLI
                     VLGYMVSYRLRKIDMLEALKSVD"
     gene            7399..7995
                     /locus_tag="TVB59_001788"
     CDS             7399..7995
                     /locus_tag="TVB59_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEL1010645.1"
                     /translation="MEAMIAAYLADHREKIPLGQVVDCFKGKAVSRKAEAGEFGLINL
                     SDMGQLGIDYHQVRAFHMDRRQLLRYILEDGDVLIASKGTVQKVCVFHKQEREMVASS
                     NITVLRPQRVLRGYYIKFFLESAIGQALLKAADHGKDVINLSTKALLDIPVPVIPLVK
                     QDYLINQYLRGLHDYQRKVNRAEQEWQFIQNEIQKGLG"
     gene            8005..8967
                     /locus_tag="TVB59_001789"
     CDS             8005..8967
                     /locus_tag="TVB59_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEL1010646.1"
                     /translation="MSLIERTIKMLLATMAAIFLASQLQLSYAISAGIIALLGVLDTR
                     KSSLIVARKRLLSFFLAFAVAVSLFALFGFGLLSIGLYLALTIPLLYQLKIEAGLVPI
                     TVLVTHLMSEQRIDLSILFNELLLFLIGTGLALLVNGYMGSQEHRLRLYHQKIEDSLK
                     AILYRFESFLLEGQGQNEGQMIKELELSLDEALKLVYRERHNTLFYHTNYQVHYFEMR
                     RHQNRLLAQMALNVTQLTSQSRESLLLSHLFHETARQLSEKNSALTLIDDIEQLLEVF
                     RQRELPQTREEFERRAILFQLLQDLERFILLKVEFYRDYKEEQA"
BASE COUNT         2598 a         1565 c         2121 g         2736 t
ORIGIN      
        1 tagttttatt gaattgagga gatttattat gggaattatt tggacattaa ttgtgggtgc
       61 acttatcggt gctattgccg gtgcgcttac taaaaaaggc ggatcaatgg gctggattgc
      121 caatatcgct gcaggactta ttggatcata cgttggtcaa gctttgtttg gcagctgggg
      181 tctaacatta gctggcatgg cacttttccc atcaatcatt ggtgctgtta tcgttgttat
      241 cattacttct tttgtactaa ataaatcaaa ctaagggcat ttctatcatt atagagatgg
      301 ttgagtagga aagaggtttt tatgtcgaaa tttttaaaaa ttagctatag tctcattggc
      361 ttagtcctat tgacggtctt tggtggcgtg atagccataa ctggagatta tattaggcta
      421 cctattggct atcaatggct tcactgggat atgaattggc ttcctaaatt cctaaatccg
      481 gccttatatt actattactt ttgggcagct atcgctttat ttctaataac agtgctgatc
      541 cttcttgtga ttatctttta tccacgcacc tatactgaga ttcagctggc taaggataaa
      601 ggaaccctgc ttttgaaagg gtctgctatt gaaggctatg tagcagctgc tattaaagca
      661 gcagggctta tgtcaagccc aagagttacc gctaagctgt acaagcgtaa atttaaggtt
      721 aatgtcagtg gacaattagc ttctcgcgta gctgtcactg agcagctaaa tggcattaaa
      781 gaaggaattg agactggttt aacagaattc tttggtatta atcgacctgt ccatttcaag
      841 gtttatgtca aggatattgc tgatgctaag caaaagcata gctctaagag acgtgtagaa
      901 taggagatta tcatggcatt ttatgaacgg tttaaatacc ctattattgg tggtctgata
      961 gggctgatag ctgctgtatt actgatgacc tttgggttat ttaaaacact gctggcaatt
     1021 attttcatta ttttaggagt atatggcggc ctgtatgcca aaaagacagg tattatcgat
     1081 caattgatca aacgtaacta aaggagattt atcatgactg aaacttacat taaaaacaca
     1141 actcataaag aaccaacttc agctgttcgt ggcgaattga cctatgatga caaggtcatt
     1201 gaaaagatcg ttggcttggc tcttgaaaac attgatggcc tactaggtgt taatggtggc
     1261 tttttggcca atctaaaaga caagcttgtt aatagtgatt ctgttcgtga tggggttaat
     1321 gttgaggttg gtaaaaaaga ggttgctgtt gatttagaca ttgtagcaga ataccaaaag
     1381 catgttccaa ccatttttga tgcgattaaa tctgtcgtag aaaatgaagt caagagaatg
     1441 acagatttag aggtgattga ggttaatgtt aaggttgttg acattaaaac caaggagcaa
     1501 tttgaagctg ataaggtcag cctacaggat aaggtgactg aggtagctcg ctcaacctct
     1561 gaatttacaa gcaagcaggt agacaatgtt aaggcatctg taggtgcagg tgtagaaaag
     1621 gttcaagagc aaactgagcc acgcgttaag taagctaggc tgtcaaacga tagaaataga
     1681 ggaaatcata atgtcagaag aaaaggtaaa tgcaaaattg gagcaagcag gcggtaaaat
     1741 caaagaagcc tttggaaagg tgactggtga taaatcctta gaaaccgaag gtaaggttga
     1801 tcaagcagcc agcaaaatca aagaagtagc tgctgatgct aaggacgctg tcaagggctt
     1861 tgttaagggc cttaagcaag ataaataagg agttgtaatg aaagcaaagg acataaaaag
     1921 tacgttgacc tacgatgata aggtcattga aaaaatcgtt ggacatgctt tagagaaggt
     1981 cagtggctta ttagcagtca atggtggctt tttctcaaat atcaaaaata acctagtgaa
     2041 tagtgactct gttcgtgatg gggtgtctgt tgaggttggc agcaaggaag tggctgttga
     2101 cttagatatt gttgttgaat atggtaagga tattccagca attgttgagt ctatcaaggc
     2161 tattgttttt caaaatgtcg atagcatgac acatttgagg gtcgttgaag taaatgtgaa
     2221 cgttgttgat attagaacca aagaagagca tgaggctgct agcgtcactg ttcaagacag
     2281 gctaacagac gcggcctcag caacctctca atttgtagct gagcaagcag acaaggtaaa
     2341 agaaactgtc tctaaaacca cagataataa cgagacagta gaataaaaca caacaactaa
     2401 aactcctgtt aatgacatat tgtgggctgg tgtgatgacc agctcttttt atcagtgctt
     2461 gaacaatgtt atgctattgt attctctgtg aaaatgtgat ttaatgggaa tggtatcatt
     2521 tgttaaaaag gagtaattat catgactagt aataagagag agattactaa ttccaagtat
     2581 caaaagattg ccatttcagt tgctgaaagg attgccaatg gcgaatatga agtgggagaa
     2641 aagctaaagt ctaggacaac cattgcttcg acctttaaag tttcgcctga aactgctaga
     2701 aagggtctga atattttagc tgatctgaag attttgacct taaagcatgg gagtggcgcc
     2761 attgtcttgt ctaaggaaaa ggctattgat tttctgaacc aatacgaatc cacccattct
     2821 atcgctgtca tcaaagaaaa tattcgccat aatattcgtg agcaggaaaa ggcaatggag
     2881 catttaacag tgcttgttaa tgagtttctg atgcaaagcc aatcaatcag caagcaatac
     2941 ccgctggcac cttacgaaat tatttgtagt caggattcag agcattttgg ccaatccatt
     3001 ggtgatttga acatttggca tcaaacggga gcgacgattg tagctattga gcatgatggc
     3061 caattcattg tttctcccgg tccttacgct gttatcgaaa aaggtgatca tatttacttt
     3121 gtcggtaatg aggacgtgat ttctagaatg aaaacctttt ttaatgttag aaagggtctg
     3181 taatcacaaa aaaacacaga gctgctttaa ggtgatggtg atatcacgat gaagtgtctc
     3241 tgtgtttttg tgttatcagg ctaaggcttc taagtagctt atagctctga ttgaagcccc
     3301 tagattactt tttcaaagcc aacagttttc aggataatag ctgtcatgtc atcggttgtt
     3361 tcttgacagt catgactaat ccagtagcta atcagacttt caatactggc tagataaacc
     3421 tcaagcgcgt agtgataagg gatctgatag tgcttggtga tgatttcttg aaagccatca
     3481 atagtggtca aaaattgata aataaaatcc ttgagtattt gtgaaaaatt caaataactg
     3541 gagttagcca tagcagcaat aaagggaaga ttatcaatga tataagcgag ggcttccttt
     3601 agaacgagtc tagtatctgt aaaaatatga gggtcattta ggagctggta taaatcgtct
     3661 aaggtgtcat ttatgagatg agtcatcata tcatgtttat ccctgtaatg cagataaaag
     3721 gtgcctctat tgacaccagc ttttttggtt aagtcagaaa cggtaatggt ctcaaagctc
     3781 ttttctgtca aaagactgac aagtgcctgc ttcaaatagg ccttggttgg tgtgtgtctt
     3841 gttgtcatcg actcatctcc ttaagtcaac aaatgctgct tatctgttct tgttaaagtc
     3901 ttgaggacat tatataataa ggctagtata aaatcaacaa ggtgttgata taaaggaggt
     3961 gacatgatca gtgtcctata ttgaaatgag gtcctcttca aagacctacc agattggaga
     4021 aacaactgtt aaggctaatg atgaggtatc ctttgagatt gaaagagggg agcttgtgat
     4081 cattttagga gcctctggtg caggcaagtc cacagtgctt aatattttag gcggcatgga
     4141 tagcaatgac caaggtcagg tcataataga cggcaaggac atctcgacct atagtaaaaa
     4201 ggcattgacc agctaccgtc gttacgaggt tggctttgtt tttcaatttt acaatctggt
     4261 gccaaatctg acagcaaagg aaaatgttga gctggcggct gatattgtgg cagatgcact
     4321 tgatccgact actgtcttaa atgaggtggg gctaggagga cgtttggagc atttcccagc
     4381 acagctatca ggaggtgagc agcaaagggt gtctattgct cgtgccttgg ctaaaaatcc
     4441 taagttgttg ctttgtgatg agccaacagg ggctttagat tatcaaaccg gcaagcaaat
     4501 tttaagattg cttcaagata tggcgcacga caagggcagg acagttattg tggtgacgca
     4561 taatactgct ctagcgccta ttgctgatcg ggtcatttat atgcatgacg gtcgtgtgac
     4621 caagacagtg cttaataagc agccgcttga tattgatagg ataacgtatt gagaggtgcc
     4681 tagatgaaac aaaaaacctt atggaaggat agttttcgag caataaaagc tagtaagggg
     4741 cgttttttgt ccttgctatt tttaatggct ctaggctcct ttgccttggt tggcttaaag
     4801 gtggctggtc ccaatatgga aaaaactgct agtcactatc tagaggagca tcaggttatg
     4861 gaccttagta tcctagcctc gcatggcttt tctgatagag ataagcaaga attagcctct
     4921 cttaaaaatg caagactaga gtatgcgagc tttgttgatg gtgcttttga tcaccagagg
     4981 aaggctatta ggctttattc tatgccacaa agcctatctc aggccagctt ggtcaaggga
     5041 gattacccta gcaaggctag cgacattttg ctatctgaag ctttatcaag ccgctatcgg
     5101 cttgggcaaa taatcacgat aagcctaaaa acaaagggat tgctaaagca tagatcctat
     5161 cgtgttgtcg gctttgctca ttctccagaa atatggtcca aaacaaactt aggtgtttcc
     5221 tcagcagggg atggtaatct ctatgcctat gcctaccttc accctagtgc ctttcagcaa
     5281 gggcacaatc tcttacgcat tcggtatgat gatttaagag ggttgaatgc cttttcaact
     5341 caatacaatg aacgattgct acaacaccaa gcagagcttg atcagatctt gcaggacaat
     5401 ggtcaagagc gttatgaaga aatgctcaat gaccttaatc gcagcttgaa agatagtaaa
     5461 gttaagctcg aagagcaaag gactgttctt aaggcaagtg aagaccagct ggctttgcta
     5521 agtggtcatg ccttagagca agcgcagact cagctaaagc aagggcagga agagttagct
     5581 aaaaaagaag caagcttgct agagttagct gaaaagcaaa gggcagcgat gatcaagcca
     5641 acctatacta gctatagtcg ctcaacgctg ccaggtggtg agggttatca aacctatgcc
     5701 acctcaacac agtccatatc gcatgttgga aatatctttc ctgttgtttt gtatttggtt
     5761 gcggccttag ttacttttac aacaatggct cgctatgttg acgaagaacg aacgaactca
     5821 ggcttactaa aggcaatagg ctattctgat tgggatatta ccaaaaaatt tctgctatat
     5881 ggtgccttag ctgccttgtt gggcactgga ttaggagttt taggagggac ttatttttta
     5941 tctcggctca tctcagctat cctaacagat gcattgacta tcggctctac tcagctttat
     6001 ttttattgga gctatagtgt ggttgcagtg cttttagcct tgttatctgc tgttttgaca
     6061 gcttatatgg tggtgagacg tgagcttttt ctcagaccct cacaactgtt gctgcctaag
     6121 cctcctagta gcggggcaag gatttggctg gagcatgtct cctttatctg gcggcgttta
     6181 tcctttacct ataaggttac ttttcgaaat atctttcgat ataagcaaag aatgctgatg
     6241 acagtaattg gagtagcagg ttctgttgcg ctcttatttt ccggcttggg cattcaatcc
     6301 tcacttgcta atagcctaag ctatcaattt ggcaagctga cagcctatga catgctcgtg
     6361 gtagaagctc caacagcaga agctcatgat aggcaggagc tggcacaata tttgaaggca
     6421 gatcagattg ctagtaagaa agagatttat tacgctaact tatcactaaa gataaaagac
     6481 ttagacaaca agcaaacagt gtcgttgatt tctagcgatc agagcactct atctccctat
     6541 tttagcttga ttggtgctgc tgaccgaaaa aagctagacc ttccaagtac tggagtgctt
     6601 atctcaaaaa agcttgctga ctattatcag gctcatgcag gagatcagct tgagcttgaa
     6661 gctagtaacg gtaaacgcta tcagttaaga gtgagtcagg ttattgacat gactgttggt
     6721 cattacttgt tcatgtctaa atcttattat cagcaggtat ttcgggatat ggaggcttca
     6781 ccatcctatt tggtaacaac agcaaaggct agtccatctg ctgtaaagga cgtagctagt
     6841 cagctcttag caatgcctgc ggttcaggct gtgtcacaac acagtagtat tgttgctact
     6901 gtgacaggga ttgtggcgtc tttggatcag gttatgacgc ttttagtact tctatcagtt
     6961 ctactagcct tggtcatttt gtatcatttg accaatatca atattgctga gagggttagg
     7021 gaattatcaa cgataagagt cttgggcttt tatgacaagg aggttacctt atacatttac
     7081 cgggaaacca tgcttttgtc tgctgttggt attttgatcg gtctctgggg tggcagctat
     7141 ttgcacgcct atatcatgaa ggtgattgct aatgattcta tgagctttgg taggacagtt
     7201 gatgcttatg tttacctagt acctgttggg gctattgtgc ttttgttgat tgtgcttggc
     7261 tatatggtta gctaccggct aagaaagatt gatatgctag aggctctaaa gtctgttgat
     7321 tagggtaaaa tagtacttga aaatcgctta ataatatgct agtattaaaa tactataatt
     7381 taatagaagg atacttttat ggaagcgatg atagctgcct atttggctga tcatagagaa
     7441 aagataccac ttggtcaggt tgttgattgc tttaagggga aggctgtttc tcgtaaggct
     7501 gaggctggtg aatttggttt gattaatctg tctgatatgg gacagctagg aattgactat
     7561 catcaggtta gagcctttca tatggataga cgacaactat tgcgctatat cttagaggat
     7621 ggagatgtct tgattgcctc aaaggggact gttcagaagg tttgtgtttt tcataagcaa
     7681 gaaagggaaa tggtagcgtc ctctaatatc acagtgctgc gtcctcagag ggttttgcga
     7741 ggctattata ttaagttctt tttggagtct gctattggtc aagccttgtt aaaggcggcg
     7801 gatcatggaa aggacgtgat taacctatcg accaaggctt tacttgatat ccctgtacca
     7861 gtgattcctt tggttaagca ggattatttg attaatcaat atttgcgagg cctgcatgac
     7921 tatcaacgga aagtaaacag agctgagcag gagtggcagt ttattcaaaa tgaaattcaa
     7981 aaaggcttgg gctagaggta aaatgtgagc ttaattgaac gaacaataaa aatgctatta
     8041 gcaacgatgg ctgcaatctt tcttgcctct cagctacagc tgtcttatgc catatcagcg
     8101 ggaattattg ccctgttagg tgtgctagac actagaaaat ctagcttaat tgttgctaga
     8161 aagcgtctgc tgtctttttt cttagccttt gctgtggcgg ttagtctatt tgccttattt
     8221 ggctttggtc tgctttccat tggcttgtat ctagcgctaa ccattccttt gctttatcag
     8281 ctgaaaatag aggcaggtct tgttcctatc actgtcttgg tgactcacct gatgtctgag
     8341 cagcgtattg atttgtcaat tctttttaat gagctgttgc tgtttttgat tgggacgggt
     8401 cttgcccttc ttgttaacgg gtatatgggg tctcaggagc atcgcctacg cttgtaccac
     8461 caaaagatag aagatagctt aaaggctatc ttgtaccgtt ttgaatcctt tttgttagaa
     8521 ggccaaggac aaaacgaggg acagatgatt aaggaattag agcttagctt agatgaggcg
     8581 ctaaagctgg tttatcgcga aaggcacaat accctctttt atcataccaa ttatcaggtg
     8641 cattattttg agatgagacg tcatcaaaat agattgttgg cgcaaatggc cttaaatgtc
     8701 actcagctaa catctcaaag cagagaaagt ctcctgctct cccatctttt tcatgagaca
     8761 gctcgtcagc tgagtgagaa gaattctgct ttgacattga ttgatgatat tgagcaattg
     8821 cttgaggtct ttaggcaaag agagctgcct cagactagag aggaatttga aagacgggcg
     8881 attctgtttc agctgttgca ggatttggag cgctttattc tactgaaggt agaattttat
     8941 cgtgattaca aggaagagca ggcatagtag ctgcttgctg ctgtgattaa gagtctggaa
     9001 aaatcatttt ctaggctttt
//
LOCUS       DARYNN010000068         8928 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.068, whole genome shotgun sequence.
ACCESSION   DARYNN010000068 DARYNN010000000
VERSION     DARYNN010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8928)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8928)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8928
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.068"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(36..3146)
                     /locus_tag="TVB59_001790"
     CDS             complement(36..3146)
                     /locus_tag="TVB59_001790"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEL1010647.1"
                     /translation="MFAQLDTKTVYSFMDSLIDLDHYFKQAKRLGYQAIGIMDQDNLY
                     GAYHFIKGCQRHGLQPILGLEVAITVKEQALTLKLVAKNDTGYQQLLKLSTEKMSGDL
                     DLDTLVQYLEGIAVIVPFSQSLRDLGLPFDYFIGIDEASDLSKIDSTERLIPLRTVRY
                     FDNAETETLQMLHAIRDNISLADTALVAKDQFLAPCQEMTAIFQEKCPEALVNLVNLT
                     ASIAYHFDTDLKLPRFNRDKPAKEELRELTESGLREKQLWKEPYQFRLAEELAIISDM
                     GFDDYFLIVWDLLRFGRSRGYYMGMGRGSAAGSLVAYSLRITGIDPVKNNLLFERFLN
                     KERYSMPDIDIDLPDIYRSEFLHYVRDRYGSEHSAQIVTFSTFGPKQAVRDVFKRFGV
                     PEYELTSLTKKIGFKDTLSTVYEKNIAFRQTINSRLEFQKAFEIAKRIEGNPRQTSIH
                     AAGIVMSDDHLTNHIPLKKGEDMMVTQYDASAVEANGLLKMDFLGLRNLTLVQKMQEK
                     VVNDYGLSIDIEAINLEDPETIALFARGDTKGIFQFEQHGAISLLKRIKPTSFEEIVA
                     TTSLNRPGASDYTQNFIKRRQGQENIDLIDPVIAPILEPTYGIMLYQEQVMQIAQVYA
                     GFTLGKADLLRRAMSKKNLVEMQRMQEDFLTGARALGRSEETARLLFARMEKFAGYGF
                     NRSHAFAYAALAFQLAYFKAHYPEVFFDVMMNYSSSDYITDALDFGFEAAQVTINTIP
                     FNDKIERHKIYMGLKNIKGLPREFSYWIIENRPFTSVESFLCSIPEKYQKTSFLEPLI
                     KIGLFDGFEKNRQKIINNLEGLLTFVNELGSLFADSSFSWVETEDYSAAEKYYFEQDL
                     LGVGMSKHPLLAVAEKSTVAVTPITKLVKDTEATLLVQIDAIRVIRTKSSGQQMAFLS
                     VTDTKQKLDVTLFPEQYAVYKQDLKEGHIYYINGRVKERDNRLQLVCHQLRLAQSQRY
                     WLLVENHQHDAAISDILTAFSGETPVIIHYQEGKETLELNHIRVDVSKDLEEAISPYV
                     LKTVFR"
     gene            3388..3759
                     /locus_tag="TVB59_001791"
     CDS             3388..3759
                     /locus_tag="TVB59_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1010648.1"
                     /translation="MSWKFDEKSPIYAQIAQHIMLQIVSQEIKSGDQLPTVREYAEIA
                     GVNPNTMQRALTELDREGIVYSQRTAGRFVTDNQELIARKRRELAINELKSFISNMIK
                     IGFERSEIIPVLSTFLEEGSN"
     gene            3759..4457
                     /locus_tag="TVB59_001792"
     CDS             3759..4457
                     /locus_tag="TVB59_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1010649.1"
                     /translation="MAQLLQLHHVSKSYKKQLAIDDLTITIPSGKIIGLLGPNGSGKT
                     TLIKLINGLLQPDKGDIVIDGFRPSVETKKIISYLPDTTYLNESMKIKDMLDFFGDFY
                     ADFDRDKATSLLKDLDLDAEERFKNLSKGNKEKAQLILVMSRKAKLYILDEPIGGVDP
                     AARDYILKTIINNYSEQASVIISTHLISDIEPVLDEAIFLKNGKLCLSGNADDLRVQH
                     QQSIDSLFREIYKV"
     gene            4467..5261
                     /locus_tag="TVB59_001793"
     CDS             4467..5261
                     /locus_tag="TVB59_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1010650.1"
                     /translation="MFGKLLKYEFRSIGKWYFALNAGVIAIAIVLSFTINTLTNNPDE
                     VGLTTSLANKMVPLTLSLTFGSLIAGSFLSTLLIIINRFNKNVFGREGYLTLTLPVTA
                     HQIILSKLLASFVCSIFNGINLLIGIFILIAPTVDFTYLLKVLKTIMKPENLVENASI
                     LIYMLLSTITSILLIYLAISIGQLFSNRRGLMAFCAYFILVIIIIVVMTYLNDAFFTV
                     NPNSSDSLLYFGDHTAISILNIEQLVEGIILYVATHFIIKNKLNIQ"
     gene            complement(5308..5919)
                     /locus_tag="TVB59_001794"
     CDS             complement(5308..5919)
                     /locus_tag="TVB59_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEL1010651.1"
                     /translation="MRNNELKPYVIWQKVIKLLGSLALVGSFLLAFWFYRLGILNDSN
                     ALKDLVHSHKVFGPLVFVGVQIVQIVFPIIPGGMTTIAGFLIFGPLLGFLYNYVGIFI
                     GSVILFLLVKTYGRRFILLFIEEQTFYKYERKLEMPYYERLFILCMLSPISPADIMVM
                     ITGLTEMSLKRFVTIILITKPLSIIGYSYLFIFGKDLILWFFH"
     gene            6010..6358
                     /gene="ssrA"
                     /locus_tag="TVB59_001795"
     tmRNA           6010..6358
                     /gene="ssrA"
                     /locus_tag="TVB59_001795"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            6841..7197
                     /locus_tag="TVB59_001796"
     CDS             6841..7197
                     /locus_tag="TVB59_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010652.1"
                     /translation="MEDTYMTQACKKFMVSTMAALALAGVCLTASTHISKADDYVYGD
                     VEYLLTPKQEGYDDLVSFLESLGLNHFDATLYSDSMADQDYKKLLADFKGKTRSEVIS
                     AVLSELAKFYNDYSPF"
     gene            7721..8770
                     /locus_tag="TVB59_001797"
     CDS             7721..8770
                     /locus_tag="TVB59_001797"
                     /EC_number="3.4.22.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515503.1"
                     /note="This family includes IgM or IgG-cleaving cysteine
                     proteases; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IdeS/Mac family cysteine endopeptidase"
                     /protein_id="HEL1010653.1"
                     /translation="MKTIAYPNKPHSLSAGLLTAIAIFSLASSNITYADDYQRNATEA
                     YAKEVPHQITSVWTKGVTPLTPEQFRYNNEDVIHAPYLAHQGWYDITKAFDGKDNLLC
                     GAATAGNMLHWWFDQNKTEIEAYLSKHPEKQKIIFNNQELFDLKAAIDTKDSQTNSQL
                     FNYFRDKAFPNLSARQLGVMPDLVLDMFINGYYLNVFKTQSTDVNRPYQDKDKRGGIF
                     DAVFTRGDQTTLLTARHDLKNKGLNDISTIIKQELTEGRALALSHTYANVSISHVINL
                     WGADFNAEGNLEAIYVTDSDANASIGMKKYFVGINAHRHVAISAKKIEGENIGAQVLG
                     LFTLSSGKDIWQKLS"
BASE COUNT         2806 a         1894 c         1569 g         2659 t
ORIGIN      
        1 attcgtttgc aaattacttc actaattcgc tatttttatc gaaaaaccgt tttcaacacg
       61 taggggctaa tagcctcctc caaatcctta ctaacatcaa ccctaatatg gtttaactct
      121 aaggtttctt tgccttcttg ataatggata ataacaggag tctcccctga aaaggctgtt
      181 aatatgtcag aaatagcagc atcatgctga tggttttcaa ccaatagcca atacctttga
      241 ctctgagcta atcgaagctg gtgacagact agctgcaagc ggttatctct ttcttttacc
      301 ctgccattga tatagtaaat atgcccctct tttaggtctt gcttatagac agcatattgc
      361 tcaggaaaaa gggtaacatc taatttctgt ttggtatcag taacactcaa aaaggccatc
      421 tgctgtccgc ttgattttgt ccgaataacc ctgatcgcat ctatttgaac cagcaaagta
      481 gcttctgtat ccttcactaa ctttgtgatt ggtgtgactg ctactgtgct tttttcagcg
      541 acagctagca aggggtgctt gctcatgcca acaccaagca aatcctgctc aaagtaatat
      601 ttctcagcag ctgaataatc ctcagtctct acccagctaa aggaggaatc cgcaaaaagt
      661 gatcccaatt cattgacaaa ggttagcagt ccttctaagt tgttaatgat tttttggcga
      721 tttttttcaa acccatcaaa caggcctatt ttgataaggg gctctaagaa gctggttttc
      781 tggtattttt caggaatgct gcacaaaaag ctttcaacac tggtaaaggg cctattttca
      841 atgatccaat acgaaaattc tctaggaaga cccttgatgt tttttaagcc catataaatc
      901 ttatgacgct caatcttatc attgaaggga atggtgttta tcgtcacctg cgcggcctca
      961 aagccaaaat ctaacgcatc tgtgatgtaa tcactgctag aataattcat catgacatca
     1021 aaaaatacct caggatagtg cgctttaaaa taggctagct gaaaggctag ggcagcataa
     1081 gcaaaggcat ggctgcggtt aaagccgtag cctgcaaatt tttccatacg tgcaaacaat
     1141 agtctggctg tctcctcaga gcgacccaag gctctagcac cagtcagaaa atcctcctgc
     1201 attctttgca tctcaacgag gtttttctta gacatagcac gccgtagcaa atcggccttt
     1261 ccaagtgtaa agcctgcata aacttgagca atctgcataa cctgctcctg ataaagcatg
     1321 ataccatagg ttggctctaa tatcggagca atcaccggat ctattagatc aatgttttcc
     1381 tgtccctgcc ggcgcttaat aaaattctgc gtgtaatcac ttgctcccgg tctatttaag
     1441 ctggttgtcg caacaatttc ctcaaagcta gtcggcttga tccgttttaa caggctaatc
     1501 gcaccatgct gttcaaattg aaaaatgccc ttggtatcac ccctagcaaa caaggctatc
     1561 gtttcaggat cctctaggtt aatagcttca atgtcaattg aaagaccgta atcgttgacc
     1621 accttttcct gcattttctg tacaagcgtc aaatttctca gaccaagaaa atccattttc
     1681 agcaagccat tagcttcaac agcactggca tcatactgag tcaccatcat atcctccccc
     1741 ttttttaagg gaatatggtt ggtcagatgg tcatcactca tcacgatacc agcagcgtga
     1801 atagaggtct gtcttggatt gccttcaatg cgcttagcta tctcaaatgc cttttgaaac
     1861 tctaagcggc tattaatggt ctgtctgaag gctatatttt tctcataaac agtgctcagg
     1921 gtatccttga acccaatttt tttagttagg cttgttagct cgtattctgg gacaccaaag
     1981 cgtttgaaca catcacgaac agcctgctta ggaccaaaag tcgaaaaggt aacaatctga
     2041 gctgagtgct cactaccata ccggtctcga acataatgaa gaaactctga gcggtaaata
     2101 tcaggcaaat caatatcaat atcaggcatg ctgtagcgtt ctttattcaa aaagcgttca
     2161 aacaataaat tgtttttgac aggatcaatc ccagtaatgc gcaacgaata agccactaga
     2221 ctgcctgctg ctgaaccacg ccccatgccc atataatagc ctctactcct tccaaagcgc
     2281 agcaaatccc agacaatgag aaaataatca tcaaacccca tatctgaaat aatagccagc
     2341 tcctctgcca gacgaaattg gtaaggctcc ttccataatt gcttttctct tagaccagac
     2401 tcggtcaatt ctcttagctc ttcttttgct ggcttatcgc ggttaaatct cggaagcttt
     2461 aaatcagtat caaaatgata agcaatcgaa gctgttagat ttacgagatt caccaaagcc
     2521 tcagggcact tttcctggaa aatagccgtc atctcctgac aaggcgctaa aaactgatcc
     2581 ttggctacta gagccgtatc tgctaagcta atattatcac gaatggcatg cagcatttgc
     2641 agagtctcag tctcagcatt atcaaaataa cgtaccgttc taagcggaat cagtctttct
     2701 gtagagtcta tctttgacaa gtcgcttgcc tcatcaatgc caatgaagta atcaaaagga
     2761 agccctaaat cacgcaagct ctgactaaaa ggaacgataa ctgctatccc ttctaaatac
     2821 tgcaccaatg tgtctaggtc taggtctcca gacatttttt cagtcgaaag ctttaagagc
     2881 tgctgatagc ctgtatcatt tttcgcaaca agcttcagcg taagagcctg ctctttaact
     2941 gtaatagcca cctcaagacc taaaatcggc tgaagcccat gcctttgaca gcccttaata
     3001 aaatgatatg ccccatatag attatcctga tccataatcc ctatggcttg atagcctaat
     3061 cgtttggctt gtttaaaata atggtctaaa tcaatcaaac tatccataaa ggaataaact
     3121 gtttttgtat ctaactgagc aaacatggac atctccttta gcgttcttac taccattata
     3181 ctatgaaaaa gactttactg cccagatttt aagcttttaa tagcagtgat ctgtctttac
     3241 tgcaccacta tcagcaggaa tcccactagc attgcaagcc agtatgtaac tagagatgac
     3301 acacaaggct tgacaagtca atcgtttttt tgtatcattt aattagtaca aatattaatc
     3361 gcagatttta gaaagaaagg agacagtatg tcttggaaat ttgatgagaa atctcctatt
     3421 tacgcacaga tagcacagca tatcatgctg caaattgtca gccaagagat caaaagtgga
     3481 gatcagctgc cgactgtccg agaatatgct gaaattgccg gcgttaatcc caacaccatg
     3541 caaagagcac ttaccgaatt agatcgtgaa ggcatagttt actcgcaacg aactgccggc
     3601 cggtttgtaa cagataacca agagcttatc gcgcgcaaaa gacgagagct ggccatcaac
     3661 gagctcaagt cctttattag caatatgatc aaaataggtt ttgaacgttc agaaatcatt
     3721 cctgttttaa gtaccttttt agaggaggga tcaaactaat ggcacaacta ttacagctgc
     3781 accacgtctc aaaatcttac aaaaaacaat tagctattga tgatttaacc ataacaatcc
     3841 cttctggaaa aattatcggc ttactaggac caaatggtag cggcaaaact acactaatta
     3901 agctaatcaa cggactttta cagccagaca agggagacat tgttattgac ggctttagac
     3961 catctgtaga aactaaaaaa atcatttctt acttaccaga tacgacctat cttaatgaaa
     4021 gtatgaaaat caaggatatg ctagactttt ttggtgattt ctatgccgat tttgacagag
     4081 ataaagcgac cagtctcctg aaggatttag acttagatgc tgaagagcgc tttaaaaacc
     4141 tatcaaaggg aaataaggaa aaggcacagc ttatcctcgt gatgagccgc aaagcaaagc
     4201 tctatatcct tgatgagcct atcggagggg ttgacccggc agcaagagat tatattctta
     4261 aaaccattat taataattac tctgagcaag cctctgttat catttctact cacctcatct
     4321 cagacattga gcctgtactt gatgaagcta ttttcttaaa aaatggtaag ctctgccttt
     4381 ctggaaacgc tgatgattta cgagttcagc atcagcaatc gattgattca ttatttagag
     4441 agatctacaa ggtttaggag gtaggcatgt ttggaaaatt attaaaatac gaatttagat
     4501 caattggcaa gtggtatttt gcgcttaatg ccggtgtcat tgctatcgcg atagtccttt
     4561 cttttaccat caatacgctt acaaacaatc ctgacgaggt tggtttaaca acaagtctgg
     4621 caaacaaaat ggttcctctc acactctcat taacgtttgg ttctctgatt gccggatcat
     4681 tcttatcaac gctattaatc atcattaatc gctttaacaa aaatgtcttt gggcgcgagg
     4741 gatacttaac actgacacta ccagtaacag cacatcagat tatcttgtcc aagctgttag
     4801 cgtcctttgt ttgcagtatt tttaatggca ttaacctatt aatcggtatc tttattttaa
     4861 tagcgccaac agttgacttt acctatctac taaaggtgct aaagacaatt atgaagccag
     4921 aaaacttagt cgaaaatgct tctatcctca tctacatgct tttgtcaacc ataacaagta
     4981 tactattgat ttatctagca atctcaattg gtcagctatt ttcaaatcgt cgtggtttga
     5041 tggcattttg tgcctatttc attttagtta ttatcattat tgtcgtcatg acttatttaa
     5101 atgatgcgtt tttcaccgtc aacccaaata gctcagactc gctactctat ttcggtgatc
     5161 atacagccat atctatttta aacatagagc aactagttga aggcattatc ctttacgttg
     5221 ctactcactt catcatcaaa aacaagctta atatccaatg ataacaaaaa gtctagccac
     5281 tgcttatcag gcaatgccta gactttttta atggaaaaac cataggatca aatcctttcc
     5341 aaagataaaa agatagctgt agccaataat tgatagtggc ttcgtgatta aaataatggt
     5401 cacaaaacgc ttcaacgaca tctctgtcag cccagtaatc atgaccataa tatctgctgg
     5461 tgaaatcgga gaaagcatac agagaataaa caatctctca taatatggca tctctaattt
     5521 tctctcatac ttgtaaaagg tctgttcctc tataaacagt aaaataaagc gcctaccata
     5581 ggtcttcaca agtaaaaaca gaatcacact accaatgaag ataccaacat agttataaag
     5641 aaaacccagc aaagggccaa aaatcaaaaa gcctgcaata gttgtcatac cacctggaat
     5701 aataggaaaa acaatctgaa caatttgcac accgacaaaa acaagggggc caaaaacctt
     5761 gtgactatga acaagatcct tgagtgcatt gctgtcattt aaaatgccaa gcctgtaaaa
     5821 ccaaaaggct agcaaaaaag atccgactaa agccagactt cctaatagct taatcacttt
     5881 ttgccatatc acataaggct tcaactcatt atttctcata gcttcatcat accataagcg
     5941 ctattttttt gccattttaa aaaaattttg ctatactagc atccgtaagt atctcatacg
     6001 cctttttatg gggttgttac ggattcgaca ggcattatga ggcctatttt gcaactcatc
     6061 ggcagatgta aaaatgccag ttaaatataa ctgcaaaaaa taacacaact tacgctttag
     6121 ctgcctaaaa accagccggc gtgacttcta taggattgct tgtgtcttat tagaggtctc
     6181 aaaacagcaa gctacgttta ggtgattgtc tagtcaccta aaaagagaac cctagactcg
     6241 caggctgatg gcttgagtta tgtgtccttg gtctgttaaa gtaagacata acctatggtt
     6301 gtagacaaat aggttagcag gtgtttggac gtgggttcga ctcccaccag ctccatcaat
     6361 acttaccgta agttaccata acttactaaa accttgttaa atcaaggttt tttctttttg
     6421 tcctgttcgt gggttaccgt aagtttctat gaaagtgata gcaaaaaaaa ggccaaaaaa
     6481 tcctttaaga acagcttgaa ttttctcttt agctaatctt atatttattt ttttataata
     6541 cttcttctac ttgcttcatt gacagcacat tatcaaattt tttcggataa ttgccctgta
     6601 ttgcctgtta tatagacatc atttactgct gctttataga tatcatctgt tatgatattg
     6661 tgcttcttta caaaatttca ataatttaat tattccaaaa gctacattta tttaattttt
     6721 taaaaacact ttattaattt aattacaaaa acatttgact tttgacagat tttgagttaa
     6781 actaacattg tgataaggaa aatatcacaa aaataacgac ggacaaagga accgttggaa
     6841 atggaggaca cttatatgac acaagcttgt aagaaattta tggtttctac aatggctgcc
     6901 ctagctttgg caggagtctg cctaacagct tcaacccaca tcagcaaagc tgatgactat
     6961 gtttatggtg acgtggaata tcttttgacg cctaagcaag aaggatacga tgatttggtg
     7021 tcattcttgg agagtctagg ccttaaccat tttgatgcca ctctttattc ggactctatg
     7081 gctgatcaag attacaaaaa gctactagct gactttaagg gtaaaactcg tagtgaagtt
     7141 atttctgcag ttctatctga attagctaaa ttttataacg actattcccc tttttaatga
     7201 aataacccaa taagttatca tagatcaaaa ctgctcagac aaccttccga gcggttttaa
     7261 cttgatagag ctatgcttct ctttgtcaat ctgcttagta accagaccat ctcctaaatc
     7321 gtccgcctag ctaatcaagt aataactgca ccattgtcct tactatccta gctaatgccc
     7381 tgatttgctg actaagcttg gctaagattg tgcaagaatc ccaataacat caaagcctac
     7441 actagctctt attagtggtc tcaataataa cagctcatgt ctaaggcatg acaccaacaa
     7501 taccaaacgg tatcatcatt ggtaaaatag gtaacgctaa cataaaccaa gctgaaatat
     7561 ccattataga gatccagtct gccagcatct ctactatctc atcactattt actaataaat
     7621 aaagcttatc aaaagcattg tctcaacaaa atattgtgat aatatataaa tgtcattaac
     7681 attatttaat gataatatca ccataacaag aaagggttat atgaaaacaa tagcttatcc
     7741 aaataaacct cactccttat cagctggtct cttaactgct atagctattt ttagcctggc
     7801 gagttcaaac attacttatg ctgacgatta ccaaaggaat gctacggaag cttatgccaa
     7861 agaagtacca catcagatca cttctgtatg gaccaaaggt gttacaccac taacacccga
     7921 gcagtttcga tataataacg aagatgtgat ccatgcgcca tatcttgctc atcaaggctg
     7981 gtacgatatc accaaggcct tcgatgggaa ggataatctc ttgtgtggcg cagcaacggc
     8041 aggtaatatg ctgcattggt ggtttgatca aaataaaaca gagattgaag cctatttaag
     8101 taaacaccct gaaaagcaaa aaatcatttt taacaaccaa gagctatttg atttgaaagc
     8161 tgctatcgat accaaggaca gtcaaaccaa tagtcagctt tttaattatt ttagagataa
     8221 agcctttcca aatctatcag cacgtcaact cggggttatg cctgatcttg ttctagacat
     8281 gtttatcaat ggttactact taaatgtgtt taaaacacag tctactgatg tcaatcgacc
     8341 ttatcaggac aaggacaaac gaggtggtat tttcgatgct gttttcacca gaggagatca
     8401 gacaacgctc ttgacagctc gtcatgattt aaaaaataaa ggactaaatg acatcagcac
     8461 cattatcaag caagaactga ctgaaggaag agcccttgct ttatcacata cctacgccaa
     8521 tgttagcatt agccatgtga ttaacttgtg gggagctgat tttaatgctg aaggaaacct
     8581 tgaggccatc tatgtcacag actcagatgc taatgcgtct attggtatga aaaaatattt
     8641 tgtcggcatt aatgctcata gacatgtcgc catttctgcc aagaaaatag aaggagaaaa
     8701 cattggcgct caagtattag gcttatttac gctttccagt ggcaaggaca tatggcagaa
     8761 actgagctaa ccagtcatca ttaggaacag accaagtgct tattggtctg ttttttcgtc
     8821 taacaatagc cctattagct cactgtcatt ggttaaagct tgtcatgaac tctttaagct
     8881 cttgttttgt taaacattaa tgtgcctgtt gttcttttct aagataag
//
LOCUS       DARYNN010000069         8693 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.069, whole genome shotgun sequence.
ACCESSION   DARYNN010000069 DARYNN010000000
VERSION     DARYNN010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8693)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8693)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8693
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.069"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(7..369)
                     /locus_tag="TVB59_001798"
     CDS             complement(7..369)
                     /locus_tag="TVB59_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComG"
                     /protein_id="HEL1010654.1"
                     /translation="MHFKRRVKAGVLLYALLMASVFLLLLQAYLSHISQLHQEYQAQM
                     DYAKAQLIAEMVYQEQPSGDGQIAFNCGQVSYKSHKQRFIIEIKLPHQQLYQFSYPEV
                     QQASQTSKKQSELKQSLP"
     gene            complement(347..781)
                     /locus_tag="TVB59_001799"
     CDS             complement(347..781)
                     /locus_tag="TVB59_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HEL1010655.1"
                     /translation="MKDSRLKAFTLIECLIALLVISGSLLVYQALTKSLMANERYLAA
                     NDQNNWLLFSQQLRAELSGTTLQGVRNNRLYVEKDKKALSFGQVKGHDFRKAASNGQG
                     YQPMLFGLSSSQITAVGQQVTIKLKWQSGLERTFIYAFQEKG"
     gene            complement(768..1058)
                     /locus_tag="TVB59_001800"
     CDS             complement(768..1058)
                     /locus_tag="TVB59_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComG"
                     /protein_id="HEL1010656.1"
                     /translation="MVIIKKQVKAYIALEGLIATGLILVIVTLILSALRYSQQELSAC
                     RQKQELLNTAVMAMQTKQRALSLNGCHIKLLSHQKGIAIVEKDQTIIRIERQ"
     gene            complement(1015..1440)
                     /locus_tag="TVB59_001801"
     CDS             complement(1015..1440)
                     /locus_tag="TVB59_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEL1010657.1"
                     /translation="MKLRSSIKAFTLLEGLLTLFLISFMLLYLSLPVSDSYARVEEHL
                     FFMRFEQAYRHLQKLSILRQKEHVLVLKPHYIKAEEAILPLPKQVKLKSTQTLTIDKL
                     GGNHSLARVVFENRDRQITYQFYLGSGNYQKTSQSLHRS"
     gene            complement(1418..1741)
                     /locus_tag="TVB59_001802"
     CDS             complement(1418..1741)
                     /locus_tag="TVB59_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HEL1010658.1"
                     /translation="MKMRLSILKDQGVQAFTLLEMLLVLLIISVLMLLFVPNLSKQKD
                     KVTDTGNAAVVKLVENQAELYELSHGEKPSLKQLQEDGSISDKQQKAYQDYYAKHKDE
                     AKKLN"
     gene            complement(1742..2728)
                     /locus_tag="TVB59_001803"
     CDS             complement(1742..2728)
                     /locus_tag="TVB59_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEL1010659.1"
                     /translation="MKKLSSKQQEKLIQLLYNLLSNGFNLTEVIAFLRKSQLLLPVYV
                     TSMEASLLKGNGLADMLAALGYSDAVMTQINLADKHGNIKLTLEKIQDYLSQFRQIKR
                     KTIEAVTYPIILLGFLVVIMLGLRHYLIPQLESQNTLTDLLLHLPHYFLGFCLLVLLL
                     IGSFYLYAKSCSRLKLFSQLSYYPIIGSLLRQYLTAYYAREWGNLIGQGLELITILEM
                     MSNEKSQLMRELAKDIKQSLLAGQSFHQRVAAYPFFKKELSLMIEYGDIKSKLGQELD
                     IYSQESWETFFSQLNRATQWIQPIIFLVVAVVIVMIYAAILLPIYQQMGDVF"
     gene            complement(2709..3647)
                     /gene="tadA"
                     /locus_tag="TVB59_001804"
     CDS             complement(2709..3647)
                     /gene="tadA"
                     /locus_tag="TVB59_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HEL1010660.1"
                     /translation="MIQELAKRLIRQAEELQAQDIYILPRGTGYELLMRVGDDRRLID
                     VCESDRMANLISHFKFVAGMNVGEKRRCQLGACDYDLDDTKVSLRLSAVGDYQGQESL
                     VIRLLYHHQRQLRYWFDGLERVTSAIGARGLYLFSGPVGSGKTTLMYQLVSDYCKELQ
                     VISIEDPVEIKNDQLLQLQVNDSIGMTYDNLIKLSLRHRPDVLIIGEIRDTQTARAVI
                     RASLTGAMVFSTVHAKSISGVYARLLELGISRAELDNSLAMVAYQRFISGGALIDCAQ
                     KEFEHHQANRWNQQIDQLLAEGHLNTRQARLEKIIQ"
     gene            complement(3829..4476)
                     /locus_tag="TVB59_001805"
     CDS             complement(3829..4476)
                     /locus_tag="TVB59_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1010661.1"
                     /translation="MIRLEKVSKCFGDRVLFSDLSMTFESGKVYALIGSSGSGKTTLM
                     NMLAALEDYQGEIFFRGKNLKTYRSSDFFRHELGYLFQHFGLLESQTIADNLKLGLIG
                     QKISKEEGRQRELEALRAVGLDYLSLEKPVFELSGGEYQRVALAKVMLKDPPFILADE
                     PTASIDPEASKAIMAILLSLRHKNRTIIIATHSPSIWEMADEVISVDQLSSLTRL"
     gene            complement(4478..6481)
                     /locus_tag="TVB59_001806"
     CDS             complement(4478..6481)
                     /locus_tag="TVB59_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEL1010662.1"
                     /translation="MKRLFIILSNILVSLFLVWVFTIWSDTFVSHYYPSVVVLDASPK
                     ASYNQVEAGLTRLADETDSLIAMQHQEPGPEGTPIVTYTLFGKGKLPGGLAEKVIEEP
                     SRLSVENNYFILKGGLTVERLRDTLAGLGMTKMTALKPSFLGTLVLIFSSGSQALGIV
                     IFCLTFGALTLIGHIRTLRAVGIRLISGERRWQIFLYPIRSDVCYCCLGLLLGLSLAA
                     IMSQLMSFSPLVLYLIGIGLVCYNLLLIAIALFFAGLFVIGIKRVHLMQVIKGQIPVR
                     GIISLILIAQLLAVLVVSFGASRTLLYVQAERQQKQGQAAWLQEDRLVTLLIGRDGLD
                     IGNTKEAIAKQKTWFHVMDQAVSEHGAILSRHYLVERDLQSGLSMLTASSSWNDYSPQ
                     GNVLLVTPQYVKHQKVEVAPDISEKINQLSLGEFVLLLPEHLKTQAAQYQSVFESAVT
                     GLASGEGHQPMTATVSYTKTGQERFLYNTTPISYQQFLRDPIIVVLTPKSTGEQAYAF
                     WEVALQNYFLFDQLADTQTLIKQNGIENWVGELKTGYRIYETLLNNLRREIWLMIAGA
                     ILGIATSMLMFNTMNLLYFEEFRRDIFIKRVSGLRFFELHRRYLLSQLLVFFVGLVIS
                     ALLTQNPLMCLLVFFLFLGNAILLLYRQMRIENKMSLLILKGA"
     gene            complement(7018..7383)
                     /locus_tag="TVB59_001807"
     CDS             complement(7018..7383)
                     /locus_tag="TVB59_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEL1010663.1"
                     /translation="MYQVIEMYGDWEPWWFIDGWQDDIVQEKSFDSWPAALAYFEEEW
                     QRMKKSYPSYHSQKSLLATFWREDERRWCEDCDEELQQYHSLLLLKDRDIVPKHHYQS
                     YFEQRNDCPQASLSCKLSI"
     gene            complement(7444..8490)
                     /locus_tag="TVB59_001808"
     CDS             complement(7444..8490)
                     /locus_tag="TVB59_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001868451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEL1010664.1"
                     /translation="MTKESQKVTDSLNTSVVSLLQYCFAIMVIVIHSGRLFQYEPLHF
                     FLKSFLGRMAVPYFLICTAFFLRGRLREANREKQYFKQILKTYLLWSLIYLPYAYAFF
                     ESLRLPKHYLPLGLCLALSYFGMCYHLWYIPALWLGWVLVQLSLKTFGKKVTLIIVAG
                     LYLLGSMETYSHFLSSTPFEPLLTGYMHIFQTSRNGIFYTPAYLCAGCLLYDHFSSSL
                     FSQRYMRKAAVCLILLALESLLIYHHQGLDKNFFLLSALFTTFLFNASVRISLLSKYS
                     LAKLKKLSYYYFFLHPMFIECSLFLLRPYQLAPATKGKLVFLMTLLATHLCSEALMLL
                     VRSQAHAKAYLKRQ"
BASE COUNT         2705 a         1992 c         1623 g         2373 t
ORIGIN      
        1 ccttagttat gggagtgatt gcttaagctc agactgcttt ttagaagtct gagaggcctg
       61 ctgaacttca ggatagctaa attgatatag ctgctgatgt ggtaatttga tctcaattat
      121 aaaacgctgc ttatgcgact tatagctaac ctgaccacaa ttaaaggcaa tctgaccatc
      181 gccagaaggc tgctcctgat aaaccatttc tgctattagc tgagcctttg cgtagtccat
      241 ctgagcctga tattcctgat gtagctggct aatatgacta agataagcct gtaacagtaa
      301 taaaaagacc gatgccatca gcaaagcata caaaagcact cctgccttaa cccttctctt
      361 gaaatgcata aataaaggtc ctttctaagc cgctttgcca tttcagcttg atggtcacct
      421 gctgacctac tgctgttatt tggctacttg acaagccaaa cagcatgggc tgatagcctt
      481 gaccattgct agctgctttt ctaaaatcat ggcccttgac ctgtccaaag gacaaagcct
      541 tcttgtcctt ttcaacatat agcctattat tgcggacacc ctgtagggta gtacctgaaa
      601 gctctgctcg caattgctgg gaaaacaaaa gccagttgtt ctgatcattt gctgctagat
      661 acctctcatt tgccataagg ctcttggtta aggcctgata aactaataaa gagcctgaga
      721 tgacaagcaa ggcaataagg cactctatca aggtgaaagc ctttagccta ctgtctttca
      781 atcctaataa tcgtttggtc tttttcaaca atagcgatac ccttctgatg tgataatagc
      841 ttaatatgac aaccattaag gcttaatgcc ctttgttttg tctgcatagc catcacagct
      901 gtattcaaca gctcttgctt ttggcgacag gccgacagct cctgttggct ataacgcagg
      961 gctgacagta tcagtgttac aataacaaga ataagtcctg tcgctatcaa gccttcaaga
     1021 gcgatgtagg ctttgacttg ttttttgata attaccactc cctaaataaa attgataagt
     1081 aatctgccga tctctatttt caaagacaac tcttgccagc gaatggttgc cgcccagttt
     1141 atcaatggtt aaggtctggg tagattttag cttgacctgc tttggtagag gcaaaatagc
     1201 ttcttcggcc ttaatataat gtggctttaa gaccagcaca tgctcttttt gacgtaatat
     1261 cgatagcttc tgtaggtgcc tataagcctg ttcaaagcgc atgaaaaaga gatgctcctc
     1321 aaccctagca tagctatctg ataccggtag tgacaagtac agcagcataa agctaatcag
     1381 aaaaagtgtc agtaaaccct ctaagagggt aaaagcttta attgagcttc ttagcttcat
     1441 ctttatgctt tgcataataa tcctgataag ccttttgctg cttgtcactg atacttccat
     1501 cctcttgcag ctgcttcagg cttggctttt ccccatgtga taattcataa agctctgcct
     1561 gattttcaac cagctttacc accgcagcat tgcctgtgtc tgtcacctta tccttttgtt
     1621 tacttaaatt tggaacaaat aacagcatca aaacactaat gattaacaaa accagaagca
     1681 tttccagtaa agtgaaggcc tgaacacctt gatcttttaa gattgataat ctcattttca
     1741 tttaaaaaac atctcccatc tgttgataaa ttggtaataa aatagcagca taaatcatca
     1801 caataaccac agcaaccact aaaaaaataa tcggctggat ccattgtgtt gcccgattaa
     1861 gctgactaaa aaaggtctcc cagctttctt gggaatagat atctaattcc tgaccaagct
     1921 ttgatttgat gtcaccatat tcaatcatta ggcttagctc ctttttaaaa aagggataag
     1981 ctgcaaccct ttgatgaaag gattggccag ctagtagact ctgcttgata tccttggcaa
     2041 gctctcgcat gagctgtgac ttttcgtttg acatcatctc taaaatggtg attaattcta
     2101 agccttgtcc gatgaggttg ccccattctc tagcatagta ggctgtcaaa tattgccgca
     2161 ataaggaccc aatgatagga taatagctca gctgactaaa tagttttagc cgactacagg
     2221 acttggcata taggtaaaaa gagccaatta gcaacagcac aagcaaacaa aaacctaaga
     2281 aataatgagg caaatgaagc aacaagtcag tcaaggtatt ttgactctct agctgaggga
     2341 ttaggtaatg acgcaagcct agcatgataa ccactagaaa acccaaaagt ataatcggat
     2401 aagtgactgc ctcgatggtc tttcgcttga tttggcgaaa ttgactcaga tagtcctgaa
     2461 ttttttccaa ggttagcttg atattgccat gcttatctgc cagattaatt tgtgtcataa
     2521 cagcatcaga gtaacctaag gctgctagca tgtcagcaag gccgttgccc tttaataggc
     2581 ttgcttccat acttgtaaca tagactggca gtagcagctg gctttttctc aaaaaagcaa
     2641 tgacctctgt caaattaaag ccgttagaca ataggttata gagcaattgg ataagctttt
     2701 cctgctgctt actggataat tttttcaagc cttgcctgcc tggtattgag atgtccctcc
     2761 gcaagaagct gatcaatctg ctgattccac cggttggctt gatgatgttc aaattccttt
     2821 tgtgcacaat caattaaagc acctccacta ataaatcgct ggtaagcaac cattgctaga
     2881 ctattatcca attctgccct agaaatgcct aattctagca gtctagcgta aacgcctgaa
     2941 atactctttg catggacggt tgaaaagacc attgctcctg ttaggctagc cctaataacc
     3001 gctctagcag tctgtgtatc tctaatttct ccgataatca acacatctgg acgatgacgc
     3061 aaggaaagct taatcagatt atcgtatgtc atgccaatgc tatcgttaac ctgtaattgc
     3121 aggagctggt cattttttat ttccacagga tcctcaatac tgatcacctg aagctccttg
     3181 caatagtcag agactagctg atacatcagg gttgtcttac ctgatcccac cggtccagaa
     3241 aagaggtaaa ggcctctagc tccaatagct gatgtgactc gctctaaacc atcaaaccaa
     3301 tacctgagct ggcgttgatg atgatacaag agacgaataa ccaagctctc ctgtccctga
     3361 taatcaccca cagctgataa tcgtagagac accttagtgt catcaaggtc gtagtcacaa
     3421 gcaccgagct gacagcgtct tttttcgccc acattcattc ctgcaacgaa cttaaagtga
     3481 ctaataagat tagccatccg atcactttca caaacatcta ttagcctcct atcatcacct
     3541 accctcatca aaagctcata gcctgtcccc cttggtagta tataaatatc ctgagcctgc
     3601 aattcttcag cctgcctgat aagccgcttg gctaattctt gaatcattct tacctcctca
     3661 ctaagactat tcgaaaaata aaaaaaatag cctcaagaaa aaggccattt tttgataaat
     3721 gtttaacatc aagtaaggaa ttcagcacgc tacaaacagc gcagaatcct tttgcgatgc
     3781 tatgatgaca aggtcaagcc ttaatcactt agctagtcca ggctttattt agagcctggt
     3841 gaggctgcta agctgatcaa cagagatgac ctcatctgcc atttcccaaa tgcttgggct
     3901 gtgggttgcg atgataattg tccgattttt atgccgaagt gacagcaaaa tagccataat
     3961 tgccttagaa gcctctggat caatagaagc cgtaggctca tcagctaaaa taaagggagg
     4021 atcttttagc atcaccttag ctagggcaac acgctggtat tcaccaccag acaattcaaa
     4081 aacaggcttt tctaagctca gataatccaa gccaactgcc cttagggctt ctaattccct
     4141 ttgccggcct tcctccttgc ttattttttg accaattagc cctagcttca aattatcagc
     4201 aatcgtctga ctctccaaca gcccaaaatg ctgaaatagg tagcccaatt cgtgacggaa
     4261 aaaatcgctg gatctgtatg ttttcaagtt ttttccacga aagaaaatct caccctgata
     4321 atcctcaaga gctgccagca tattcatcaa ggttgtctta ccactaccgc ttgacccaat
     4381 cagggcataa acctttccag actcaaaggt cattgacaaa tcagaaaata agacacgatc
     4441 accaaagcat ttactaacct tttctaatcg aatcatacta agctcctttc aaaatcagca
     4501 gcgacatctt attttctatt ctcatttgcc gatatagtag caatatggca ttccctagaa
     4561 ataggaagaa aaccagcagg cacataagag gattctgtgt taacagggca ctaatcacca
     4621 atccaacaaa gaaaacaagc agctgcgaca gcaaataacg acgatgcagc tcaaaaaatc
     4681 taagaccaga gacgcgctta atgaaaatat cccgtctaaa ttcttcaaag tagagaaggt
     4741 tcattgtgtt aaacatcaac atagaggtcg ctatccctaa tatagctcct gcaatcatca
     4801 accaaatctc cctacgaaga ttgttcaaca atgtctcata aatgcgatag ccagttttta
     4861 gctctcctac ccagttctca ataccgtttt gcttgatgag cgtttgagta tctgccaact
     4921 gatcgaaaag gaaataattt tgtaaagcaa cctcccaaaa ggcataggct tgttcgccag
     4981 ttgacttagg cgtcaaaaca acaataatgg gatcccttaa aaactgctga taggatatcg
     5041 gtgttgtgtt ataaagaaag cgttcctggc ctgtctttgt ataagaaaca gtagcagtca
     5101 tcggctgatg accctcacct gaagcaagcc cagttacagc tgattcaaag accgattggt
     5161 actgtgcagc ctgtgttttc aaatgctctg gtaaaagaag gacaaattct ccaagggaca
     5221 gctgattgat tttttcacta atatcaggtg ccacctcaac tttttggtgc ttcacatatt
     5281 gaggcgttac aagcagcaca ttcccttgtg gactgtaatc attccaacta gaagaggctg
     5341 ttagcataga gaggcctgat tgcaggtcgc gctcgactag gtaatgacga gacaggatcg
     5401 ctccatgctc tgaaacagcc tgatccataa catgaaacca agtcttttgt ttggcaatag
     5461 cttccttcgt atttccaata tctaagccat cacgtcctat taaaagagta accagcctat
     5521 cctcttgtag ccaagcagcc tgcccctgct tctgctgtct ttcagcctgg acataaagaa
     5581 gggtccggct agcgccaaag gaaacaacca gcactgccaa caattgggca attaaaatca
     5641 agctaatgat acctctgaca ggtatctgac ctttaatcac ctgcatcaaa tgcactcttt
     5701 taatcccaat tacaaataaa ccagcaaaga aaagggcaat agctatcagc aaaagattat
     5761 agcaaacaag acctatccca atcaggtaaa gaacaagcgg tgaaaaagac ataagctgac
     5821 tcataatagc cgccaggcta aggccaagta gtaggcctag acagcaatag cacacatcag
     5881 acctgattgg ataaagaaag atctgccagc gacgttcacc tgaaatcaag cggataccca
     5941 ctgctcgcag cgtgcgaata tggccaatca aggtcaaagc cccaaaggtt agacagaata
     6001 tcacaatccc taaagcctga gaaccactgc taaaaatcaa aacgagagtc cctaaaaatg
     6061 aaggcttcag cgctgtcatt ttggtcatac cgagcccagc taatgtgtct cttagtcgct
     6121 ctacagtcaa gccgccttta agaataaagt aattattctc cacactaagc cttgatggtt
     6181 cctcaataac cttttcagct agtccaccag gtagctttcc cttgccaaat aaggtatagg
     6241 tcacaatagg tgtaccttct ggccctggct cctggtgctg cattgcaatt aagctgtctg
     6301 tttcatctgc tagacgggtt aagcctgctt caacctgatt atagcttgcc ttaggcgaag
     6361 catctaaaac aacaacagac ggataataat gagaaacaaa ggtatctgac cagatcgtaa
     6421 atacccaaac caaaaagagg ctaactagta tattagacaa tatgataaac agtctcttca
     6481 taacccactc cttaccttaa aagggacgga gtctctccgc ccctaataaa cacacactga
     6541 cctgcctatt tccctgcatc aaaggtcacg tgctctccaa aattagtatt gataaaagca
     6601 taggagtagt aaccagcacc agaccatgca cgcctctgat tatcacgtcc tgagctctcc
     6661 acaaaggacc ggtgagaaga ggtcagaagg tcacctattg aaaacgcctt caatcataaa
     6721 ggacatggcg attaccacaa taccactcaa atcattaact atttaacaaa aatataccat
     6781 attctgttaa cgtttacaat gttatattta atccattttt ataaaaaaat aacattatat
     6841 catgcctcaa atgattttat cataatgagg ctcgctatgt tgttttctct atcccaatca
     6901 ggcactgcta gattagacat ctttccagac aacaaaaata gcctaaggtc agctctctaa
     6961 ttagctgatc ttaggctatt tgagtgataa tagatttgac tgatagctgt aagcctctca
     7021 gatgcttaat ttacagctaa gggaggcttg tgggcagtca tttctttgct caaaatatga
     7081 ctgataatga tgctttggca caatgtctct atcctttagc aataaaagag agtgatactg
     7141 ctgcagctcc tcatcgcaat cctcacacca tcttcgctca tcttccctcc aaaaggtagc
     7201 caataagctt ttttgactgt ggtagctggg atagctcttt ttcatgcgct gccattcttc
     7261 ctcaaaataa gccagtgcag caggccagct gtcaaacgat ttctcctgaa caatatcgtc
     7321 ttgccaacca tctataaacc accaaggctc ccagtctcca tacatttcaa tcacttgata
     7381 catgttctca tttcctctat tgcctattat agccgaagaa agatattttt aaaaaacatc
     7441 tgctcactgc cttttaagat aggccttggc atgagcttga gaacgtacca gcagcataag
     7501 ggcctctgag caaagatgag tagctagcag ggtcatgaga aagaccagtt tcccttttgt
     7561 ggccggggca agctggtagg gccttagcag aaatagcgaa cattcgataa acattgggtg
     7621 caagaaaaaa taataatagc ttagcttttt taatttagct aaagaatatt tagacagaag
     7681 gctgatacgg acactggcat tgaataaaaa ggtagtaaac agcgcagaaa gcaagaagaa
     7741 atttttatcc agaccctgat gatggtaaat aagcaggctt tccaaggcca ataagatcag
     7801 gcaaacagcc gcctttctca tatacctctg agaaaaaagc gacgatgaaa agtgatcata
     7861 gagcaagcag cccgcacaaa gataagcagg ggtgtaaaaa ataccattgc gacttgtttg
     7921 aaaaatgtgc atgtagcctg tcagcaaagg ctcaaaaggc gtcgagctta aaaaatgaga
     7981 ataggtttcc atactcccta gtaaatacaa gcccgccact atgatgagcg ttaccttctt
     8041 accaaaggtc ttcagagaaa gctgaacaag cacccacccc agccataaag caggaatata
     8101 ccacagatga tagcacatcc caaaataact aagggctaaa cacaagccaa ggggaagata
     8161 atgcttaggc agacgaagcg actcaaaaaa ggcataagca taagggaggt aaatcagaga
     8221 ccaaagcaaa taggttttta gtatttgctt gaagtactgc ttttcccgat tcgcctctct
     8281 aaggcggcct cttagaaaaa aggcggtaca aatgagaaaa taaggcaccg ccattcttcc
     8341 taaaaagctt ttcaaaaaga aatgcagcgg ctcatactga aacagcctac cgctatgaat
     8401 aacaataacc attatggcaa aacagtattg taacaggctt accacagagg tattgaggct
     8461 gtcagtgact ttctggctct cttttgtcat caattcaatc actttctttt aagagattaa
     8521 tatacgtata acttttagta tttatcgcat ttgtctctca ttttgattaa tattgttttt
     8581 atcatagcgt aatataacca attaatctaa tgattttagc ataacaaaag gagctaaggc
     8641 tagctcctga acatcacaaa agagcagacg aacttcatct cctctcgtgc tta
//
LOCUS       DARYNN010000070         8589 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.070, whole genome shotgun sequence.
ACCESSION   DARYNN010000070 DARYNN010000000
VERSION     DARYNN010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8589)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8589)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8589
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.070"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            44..286
                     /locus_tag="TVB59_001809"
     CDS             44..286
                     /locus_tag="TVB59_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010665.1"
                     /translation="MISCTLLASLLLTGCHSLSLQLAEAVQEKPIQAVTVEDLTRHGI
                     AESLKAYLQTMGLTNEEAMKQYEEVLSDEIIQYFSS"
     gene            complement(408..1622)
                     /gene="thiI"
                     /locus_tag="TVB59_001810"
     CDS             complement(408..1622)
                     /gene="thiI"
                     /locus_tag="TVB59_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEL1010666.1"
                     /translation="MKYSEIMVRHGELSTKGKNRMRFINRLKANIQDVLSAYSEVTVR
                     STRDRTHVLLNGADDRSVIEALKPVFGIQGLSPVYKVEKSVPVLIAAVQEIMSSLYRE
                     GLTFKISSKRSDHQFELDSRDLNHTLGAAVFEALPHIKAQMKNPDVTLKVEIRDEAAY
                     LSHEDIKGAGGLPVGASGKGMLMLSGGIDSPVAGYLSLKRGVEIEAVHFASPPYTSPG
                     ALRKAKDLTQRLTRFGGNIQFIEVPFTEIQEEIKHKAPEAYLMTLTRRFMLRITDAIR
                     EKRKALVIINGESLGQVASQTLESMQAINAVTSTPIIRPVVAMDKLEIIDIAQQIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKLANVERYESRFDVDGLVERAVAGIRVTEITPEIE
                     TDSLSTLIEELL"
     gene            complement(1624..2766)
                     /locus_tag="TVB59_001811"
     CDS             complement(1624..2766)
                     /locus_tag="TVB59_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEL1010667.1"
                     /translation="MIYFDNAATTKPYEEALKTYQEVASKIYGNPSSLHQLGANASRI
                     LEASRRQIAALLDVEAKEIFFTSGGTESDNWAIKGIAFEKSHFGKHIIVSAIEHPAVR
                     ESAKWLESQGFELSYAPVTDKGVVDVKKLAALIRKDTILVSIMAVNNEIGSIQPIAAI
                     SELLADKPTITFHVDAVQAIGKLPVEAYLTARVDLASFSGHKFHAVRGVGFLYKKSGK
                     RITPLLVGGGQEDELRSTTENVAAIASMAKALRIITERQDRSQARIAAMKKVIYQALQ
                     AYEDTILFSEIDDFAPHILTFGIKGVRGEVIVHAFEKHEIYISTTSACSSKVGKSAGT
                     LVSMGIPAALAQTAVRISLDDDNDMGQVEQFLTIFKQIYEKTQKVR"
     gene            3006..3446
                     /locus_tag="TVB59_001812"
     CDS             3006..3446
                     /locus_tag="TVB59_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010668.1"
                     /translation="MSSHYSRQQKPKKSASIPTKHIKTGFTALQKTIALVGSVLSIVV
                     ATITINRALQPSNEQPKSDSSPSSTSTIVKIIEKESSHSNKEETDKTETNSDSSGTQA
                     THTTPSSADPATKDTEKQQNTETEAPAANQPTANEPAPNSTSNP"
     gene            complement(3516..4868)
                     /gene="gorA"
                     /locus_tag="TVB59_001813"
     CDS             complement(3516..4868)
                     /gene="gorA"
                     /locus_tag="TVB59_001813"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEL1010669.1"
                     /translation="MAIQYDYIVIGGGSAGIASANRAAMYGAKVLLAEGKAIGGTCVN
                     LGCVPKKVMWYGAQVAETIHTYAKDYGFTVLEDRFDFKTLKSNRQAYIDRIHASYEKG
                     FEHNGVDRIYDYARFIDQHTVDIAGKTYTAPHILIATGGQPIFPDIEGAELGISSDGF
                     FALDDIPKRTAVVGAGYIAVEIAGVLNALGSQTDLLVRYDRPLRTFDQDIIQVLVDEM
                     KVSGPRLHTNADVTKVTKANDGSLQVHLSDGRRLEVDQVIWAIGRKPNVTGFGLEHTG
                     VELDKKGYIAVDAYENTSVDGIYAVGDVNGKLALTPVAVAAGRRLAERLFHNKPNEKL
                     DYNKVATVVFSHPPIGSIGLTEEAAIQAYGQAAVRVYQSQFTSMYTAITSHRQPCLMK
                     LIVAGEEETIVGLHGIGYGVDEMIQGFAVAIKMGATKADFDNTVAIHPTGAEEFVTMR
                     "
     gene            complement(5062..5403)
                     /locus_tag="TVB59_001814"
     CDS             complement(5062..5403)
                     /locus_tag="TVB59_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEL1010670.1"
                     /translation="MSQDIYDYANKLERAVRALPEYRKALEAREEIKADEAASQLFDE
                     FVAVQEKLQGLMQTGQLPTETEQADIQALSQKIEANDLLKGYFNAQQALSVYVNDIER
                     IVFAPLKDLAK"
     gene            complement(5464..6630)
                     /gene="aroC"
                     /locus_tag="TVB59_001815"
     CDS             complement(5464..6630)
                     /gene="aroC"
                     /locus_tag="TVB59_001815"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEL1010671.1"
                     /translation="MRYLTAGESHGQALTAIIEGIPAGLALSAELINKELKRRQGGYG
                     RGARMRIESDRVHISSGVRHGKTTGAPITLTIQNKDHQKWLDIMAVEAVEEQIKFKRK
                     ITRPRPGHADLVGGIKYRFDDLRNALERSSARETAMRVAVGAIAKAILTELGIETANH
                     VLVFGGIEVAVPEAMSFADIKKVAESSDLSIVNPKQEATIKAHIDQVKKEGDTLGGII
                     ETLIHGLPAGLGSYVQWDRKLDAKIAQAVLSINAFKGVEFGMGFDMGYQKGSQVMDDI
                     IWHETSGYSRRTNRLGGFEAGMTTGQPIVVKGVMKPIPTLYKPLMSVDTETHEPYKAT
                     VERSDPTALPAAGVVMENVVATVITKEILEQFPSDNMTDLKQAFFAYRDYVHHF"
     gene            complement(6743..7423)
                     /locus_tag="TVB59_001816"
     CDS             complement(6743..7423)
                     /locus_tag="TVB59_001816"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEL1010672.1"
                     /translation="MKIVAPVMPRNVEEAQSIDVSKYQDVNLIEWRADFLPKEDIVSV
                     APAIFEKFAGREIIFTLRTSQEGGHITLSDQEYVDLIKEINAIYNPDYIDFEYFSHKA
                     VFHEMLDFPNLVLSYHNFDETPENLMEAFSEMTKLAPRVVKIAVMPQSEQDVLDLMNY
                     TRGFKTLNPEQEFATMSMGKLGRLSRLAGDVVGSSWTFVSLDQASAPGQVSLADMKRI
                     LHVLESED"
     gene            complement(7420..8583)
                     /locus_tag="TVB59_001817"
     CDS             complement(7420..8583)
                     /locus_tag="TVB59_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEL1010673.1"
                     /translation="MNKVCINPLVERKIAAGIQLLDEKDFDGTIWDYQLVQLVNSSHQ
                     LIGTAYLSKQHKGVGWYLGRSVKKLSVSYFVTLFKTAKKKREHFAASEWTNAYRLFNQ
                     DGDDFGGLTIDLYKDFALFSWYNVFVYQEKELIIQAFREVFPEVRGAYEKIRFKGPDK
                     ETAHLYGAFAPDTFTILENGVAYQVFLNDGLMTGIFLDQHEVRRGLVDGLALGKTVLN
                     LFSYTAAFSVAAAMGGAVETTSVDLAKRSRELSKAHFVQNQLDLSSHQLVVMDVFDYF
                     KYAKRKQLSFDLIIIDPPSFARNKKQTFSVSKDYHQLIAEALDLLAPKGTIIASTNAA
                     NMTVNQFKKQIIKGLGGRPLAQMTLEQLPSDFTINKADERSNYLKVFTIRVRE"
BASE COUNT         2513 a         2050 c         1610 g         2416 t
ORIGIN      
        1 atataatttt catgaaagga gggaaatata tgaaaaatct atattgataa gttgtacact
       61 attagccagt ctcttattaa ctggctgtca ctcattgtct ttgcagctag ctgaggctgt
      121 tcaggaaaag cctattcaag cggttacggt agaggatttg accagacatg gcattgccga
      181 atccttgaaa gcctacctac agacgatggg cttaaccaat gaagaggcta tgaaacaata
      241 cgaggaggtc ctttctgatg agattatcca gtattttagc agctaaataa gagaatttga
      301 gcaaaatcag ctaaaaacaa aagccagagc ctttaataac taataggtct ggcttttttt
      361 gactgtttag atagactgct tatgttgtag ggctaggtgc gcacctccta caacaattcc
      421 tcaataagcg ttgataagct gtcagtttcg atttcaggag tgatctcagt tactctgatc
      481 cctgccactg ctcgctcgac caatccgtcg acatcaaagc gagactcata tcgttcaaca
      541 tttgctagct tgggattggt tttgggacga tcaggagcaa aaatagtaca gcagtcttca
      601 aagggctgaa tggaaatatc aaaggtgtca atttgctgag cgatatcaat gatttctagc
      661 ttatccattg ccacaactgg tctgataatc ggagttgaag tgactgcatt aatagcctgc
      721 atgctctcta aggtctggct tgcaacctgt cctaagcttt caccgttaat aatcactaaa
      781 gcctttcgct tctcacgaat agcatctgtg atccgcagca tgaagcgtct agtaagtgtc
      841 atcaaatagg cttcgggtgc cttatgcttg atctcctctt gaatctcggt aaatggaacc
      901 tcgataaact gtatattacc tccaaaacgt gttaagcgct gcgttagatc cttggctttt
      961 cttagcgcac caggactggt atagggtggg cttgcaaaat gcactgcctc aatctcaaca
     1021 cctcgtttca gggatagata gcccgcaacc ggtgaatcaa taccacctga tagcatcagc
     1081 attccctttc ctgaagctcc aaccggcagc cctccagctc cctttatatc ttcgtgagac
     1141 agataagcag cctcatcacg aatttcgacc tttagggtaa catcaggatt tttcatctgt
     1201 gccttgatat gcggcaaagc ctcaaagacg gctgctccta aggtgtggtt gaggtcgcgg
     1261 ctatctagct caaactgatg gtcactacgc ttgctggata ttttaaaggt tagcccttcg
     1321 cgatacaagg agctcataat ctcctgaact gctgctatca gtacagggac acttttttca
     1381 actttataga caggagataa gccctgaata ccaaacaccg gctttaaggc ttcaatcaca
     1441 gacctatcat ctgcaccatt aagtaaaaca tgggtcctgt ctcgagttga tctgactgtc
     1501 acctcagaat aggcagaaag aacatcttga atattagctt ttagccgatt aataaaccgc
     1561 atacggtttt ttcccttggt cgataactcc ccatgacgaa ccattatttc tgaatatttc
     1621 atattatcta accttttgtg ttttttcata aatctgttta aaaatcgtta aaaattgctc
     1681 aacctgtccc atatcattat catcatctag gctgatacgg actgctgttt gagccaatgc
     1741 tgctggaatt cccattgaga ctaaggttcc tgccgacttt ccaacctttg atgagcaggc
     1801 actcgttgtt gatatataaa tctcatgctt ttcaaatgcg tgcacaataa cctctccacg
     1861 aacgcccttt ataccaaagg tcagaatatg aggagcaaaa tcatctatct cagaaaagag
     1921 aatggtatcc tcataggcct gcaaggcttg ataaataacc tttttcatgg ctgctatcct
     1981 tgcttgagat ctatcctgtc tttctgtgat gatccttaaa gccttggcca tacttgcaat
     2041 agctgccacg ttttcagttg tcgaacgtag ctcatcttct tgaccgccac cgaccaataa
     2101 gggagtgatt cgctttcctg attttttata aagaaagcca acaccacgaa cagcatgaaa
     2161 tttatgacca gaaaaagaag ctaagtcaac acgcgcggtt aagtaagcct caacaggaag
     2221 cttcccaata gcctgaacag catcgacatg aaaggtaatg gtgggcttat cagccaaaag
     2281 ctctgatatg gctgcaatcg gctgaattga cccaatctca ttgttaaccg ccataatgga
     2341 aactaatatg gtatcttttc ggattaaggc agctagcttt ttgacatcaa caactccctt
     2401 atctgtgaca ggagcataag acagctcaaa gccttgactt tctagccatt tggcgctttc
     2461 tctgacagct gggtgctcaa tggctgagac aatgatgtgc ttaccaaagt gagatttttc
     2521 aaaggcaatc cccttgatag cccaattgtc gctttccgtt ccgccagagg taaagaaaat
     2581 ctctttggcc tctacatcaa gtaaggccgc tatttgcctg cgcgaagcct ccaatatacg
     2641 actggcattg gctcctagct gatggagact agagggattg ccgtaaatct tactggccac
     2701 ttcctgatac gttttaagtg cctcttcgta aggcttggta gtggctgcat tatcaaaata
     2761 aatcatgtgt caccttcatt tttattcaat actttattgt atcacaaatt tgatgaaatg
     2821 aaaaaataga tctttttgca ggataggaca actctatcct agacaataag gtaaaccgtt
     2881 gacttgattt ttgttctaga ttatactggt agatgataga gctaagtctg aaatgcctgt
     2941 tagccattaa agacctaaag catttgactt tagctagcct atgactcgtt aaaggagata
     3001 ttctcatgtc atcacattat tcacgtcaac aaaagcctaa aaaatcagca agtattccca
     3061 caaagcatat taaaactggc tttaccgccc ttcaaaaaac cattgcctta gttggtagtg
     3121 ttctgagtat tgttgtagcg acaatcacta ttaatcgagc tctacaacca tcaaatgagc
     3181 aacccaaaag cgattcctct ccgtcatcaa catcaacgat tgtgaaaatt attgaaaagg
     3241 agtcgtcaca ctcaaataag gaagagactg acaagacaga aactaattct gattctagcg
     3301 gtactcaggc gacacatact actcctagct cagctgatcc tgctactaag gatacagaaa
     3361 aacaacagaa taccgaaacg gaagcaccgg ctgctaatca acccacagct aatgagccag
     3421 ctcctaacag tacaagcaat ccataacaca aaacacgata acaggcaatt cagataagct
     3481 ctgaattgtc tgctatcgtg ttttatcatg tgctgttatc tcatggtaac aaactcttca
     3541 gcacctgtag ggtgaatggc aacagtattg tcaaaatcag ccttagtagc ccccatttta
     3601 atggcaacag caaagccttg aatcatctca tcaacaccat aaccaatacc atgcagacca
     3661 acgatggtct cttcttctcc tgcaacgatc aatttcatta ggcagggctg gcgatgacta
     3721 gtaatagctg tatacatgga cgtaaattgt gattgataga cacgaacagc cgcttgccca
     3781 taggcttgaa tagctgcctc ttctgttaag ccgatcgagc caattggcgg atggctaaag
     3841 acaactgtcg caaccttgtt ataatcaagc ttttcattgg gcttattatg aaacaagcgc
     3901 tctgccaagc gacgacctgc tgcgacagcg actggggtca aagcaagctt tccattaaca
     3961 tcaccaacag catagatgcc atcaacagat gtgttttcat aagcgtcaac agcaatatag
     4021 cccttcttat ccagctcaac tcctgtatgc tccaagccaa agcctgtcac atttggcttg
     4081 cggccaattg cccaaatcac ttggtccact tcaagcctac gaccatcgga caaatgcact
     4141 tgaagagagc catcattagc cttggtaacc ttagtaacat cggcattggt atgcagcctt
     4201 ggtccagata ccttcatctc atcgaccaga acctggataa tatcctgatc aaaggtcctc
     4261 agtggcctgt catagcgaac cagcaaatcc gtctgagaac ctagggcatt gagcactcct
     4321 gcaatctcaa cagcaatata gccagcaccg acaactgctg ttcgttttgg aatatcatct
     4381 aaagcaaaga aaccatctga gctaatcccc agctcagctc cttcaatgtc aggaaaaata
     4441 ggctgaccac cagtagcgat taaaatatgg ggggctgtat aggtcttacc tgcaatgtca
     4501 accgtatgct gatcaataaa tcgtgcataa tcataaatac gatcaacccc gttatgctca
     4561 aagcccttct cataagaggc atgaatacga tcaatatagg cctgacgatt gctttttaag
     4621 gttttaaaat caaacctatc ctctaacacc gtaaacccgt aatccttcgc ataggtatga
     4681 atcgtttctg ctacctgtgc gccataccac atgacctttt taggcacgca gcccaaatta
     4741 acacaggtcc ctccaatagc cttgccctca gctaatagga ccttagcacc gtacattgct
     4801 gcacgattcg ccgaggcaat cccagcgctc ccaccaccaa tcacaatata atcatactga
     4861 attgccatta atttaccacc tttactctta atgcttgcct caatagattt gttattaagc
     4921 tatcattatt gctttatttt aatctactgt catttgacta taacataaaa taacttgtgt
     4981 ctcaaatccc tgctacgaca aaaaaagatt gtgataagca tcaacaatcc tttcttctct
     5041 taatcctaag ccagcttagc tctacttggc caaatccttc aatggtgcaa atacaatccg
     5101 ttcaatatca ttaacataga cggaaagagc ctgctgagcg ttaaaatacc cttttaatag
     5161 gtcattggcc tcaatttttt ggctgagagc ctgaatatct gcctgctctg tctctgttgg
     5221 cagctgaccg gtctgcatga gtccttgcaa tttttcttgc acagcaacaa actcatcaaa
     5281 tagctgactg gcagcctcat ctgccttaat ctcttctctg gcttccaagg ccttgcgata
     5341 ctctgggagc gcacgaacag ctcgctcaag cttattggca taatcataaa tatcttggga
     5401 catctggatc tccttttatc atttattatc cttatcatat cacaatatca agccatttgt
     5461 cgcttaaaaa tgatgaacat agtcacgata ggcaaaaaaa gcctgcttta aatcggtcat
     5521 attgtctgat ggaaattgtt ccaaaatctc ttttgtgatg acagttgcta caacattttc
     5581 catcacgaca ccggcagccg gcagagccgt aggatcagaa cgctcaacag tagccttgta
     5641 aggctcgtgc gtctcagtat ccacagacat taggggcttg tagagggtgg gaatcggctt
     5701 catcacccct ttgacaacaa taggctgacc agtagtcata cctgcctcaa agccacctag
     5761 tcggtttgtt cgacgactgt agccgcttgt ctcatgccaa atgatgtcgt ccatgacctg
     5821 cgagcctttt tggtagccca tgtcaaagcc cataccaaat tcgacccctt taaaggcgtt
     5881 gatagacagg acagcctgcg cgattttggc gtctaattta cgatcccact gaacatatga
     5941 acctaagcct gctggtaagc catgaatgag tgtttcaata ataccaccaa gcgtatctcc
     6001 ttcttttttg acttgatcaa tatgggcctt gatagtcgcc tcttgcttgg gattgacaat
     6061 agataaatca gaagactctg ctactttttt gatatctgca aaggacatcg cctcaggcac
     6121 agctacctcg ataccaccaa aaactaggac atgattagca gtttcgatcc caagctcagt
     6181 aaggattgcc ttagcaattg caccaacggc cacacgcatc gctgtttctc tggcagagga
     6241 gcgctcaagc gcatttctta aatcatcaaa acgatatttg atccccccaa ccaagtcagc
     6301 atgaccaggg cgtggacgag tgattttacg cttgaacttg atttgctctt caacagcctc
     6361 aacagccata atgtctagcc atttttgatg gtccttgttt tgaatggtta aagtaattgg
     6421 tgctcctgtt gttttgccat gacgaacacc tgaagagata tgcacacgat ctgattcaat
     6481 gcgcatgcgt gcgccacgac catatccccc ctgccgacgc ttcagttcct tgttaataag
     6541 ctcagctgat aatgctaagc ctgcaggaat tccctctata atggccgtca aagcttgtcc
     6601 atgtgactca cctgctgtta aatacctcat tattcctcca tttatcaatc atagacataa
     6661 aaagcaaacc tgccctcctc tagacaacta aaagacatta ttctaagcta tccaagagaa
     6721 taatgtctgt taccgtatct tatcaatcct cagattccaa aacatgaaga atccttttca
     6781 tatcagccaa ggaaacctgc cctggtgcac tggcttgatc taaggacaca aaagtccacg
     6841 aggaccctac aacatcacct gccaagcgtg atagtctgcc tagctttccc attgacatgg
     6901 ttgcaaattc ctgctctggg ttaagtgttt taaagcctct ggtataattc atcaaatcca
     6961 aaacgtcctg ctcgctctgt ggcatgacag caatcttgac aacgcgagga gctagcttag
     7021 tcatctccga aaaagcctcc atcagatttt caggcgtctc atcaaaattg tgataagaca
     7081 agacaagatt cggaaagtca agcatttcat gaaagacagc cttgtgacta aagtattcaa
     7141 agtcaatata gtcaggatta taaatcgcat tgatctcctt gatcaaatca acgtattcct
     7201 gatcagaaag tgtaatatgc cctccttctt gacttgtacg aagggtaaaa ataatctctc
     7261 tacctgcaaa tttttcaaaa atagctggcg ctacagaaac aatatcctcc ttaggaagaa
     7321 agtctgctcg ccactcgatt aaattaacat cttgatattt agaaacgtcg atagattgag
     7381 cctcttcaac atttcttggc atgactggtg ctacaatttt cattctcgta cccttatagt
     7441 aaataccttt aaataattac ttctttcatc tgctttattg atagtaaaat cacttggaag
     7501 ctgctcaagt gtcatctgag ctaatggcct gcctcccaat cctttgataa tttgcttttt
     7561 aaactggtta acagtcatat tggcagcatt tgttgaagcg ataattgttc ccttgggggc
     7621 caataggtct agagcctcag cgattaattg atggtaatcc ttactcactg aaaacgtctg
     7681 ctttttgttt ctggcaaagc ttggtggatc aataataata agatcaaaag aaagttgctt
     7741 tcgcttagca tacttaaaat agtcaaaaac gtccataacc acaagctgat gactggatag
     7801 gtccaactga ttttgaacaa aatgagcctt tgataactct ctggagcgct ttgccaaatc
     7861 aacagaggtt gtctcaactg caccgcccat tgctgcagct acagaaaaag ctgctgtata
     7921 tgagaacagg tttaaaacag tctttccaag cgccaagccg tccaccagac ctcgtctaac
     7981 ctcatgctga tcaagaaaaa tccctgtcat caagccatca tttaaaaata cctgataggc
     8041 tacgccattt tctaaaatgg taaaggtatc aggagcaaac gcgccataca aatgagccgt
     8101 ctccttatct ggtcccttaa agcgaatctt ttcataagct cccctgacct caggaaaaac
     8161 ctctcgaaaa gcctgaataa taagctcctt ttcttgataa acaaagacat tataccaaga
     8221 aaataaagca aagtccttat agaggtctat ggttagtcct ccaaaatcat caccgtcttg
     8281 gttaaaaaga cggtaagcat ttgtccattc agacgcggca aaatgctctc ttttcttctt
     8341 agctgtctta aataaggtca caaaataaga aaccgacaat ttcttaacag accttcctag
     8401 ataccagcct actcccttat gttgctttga aaggtaagct gtgccgatga gctgatgaga
     8461 tgaattcaca agctgcacta actggtagtc ccaaatggtg ccatcaaaat ccttttcatc
     8521 tagtaattgt atccctgctg ctatcttgcg ttcaacaagg ggattaatac agaccttatt
     8581 catagtttc
//
LOCUS       DARYNN010000071         8348 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.071, whole genome shotgun sequence.
ACCESSION   DARYNN010000071 DARYNN010000000
VERSION     DARYNN010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8348)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8348)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8348
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.071"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(84..1860)
                     /locus_tag="TVB59_001818"
                     /pseudo
     CDS             complement(84..1860)
                     /locus_tag="TVB59_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738789.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(1860..3605)
                     /locus_tag="TVB59_001819"
     CDS             complement(1860..3605)
                     /locus_tag="TVB59_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1010674.1"
                     /translation="MALIWSYLKTRPKWICFDIVGGLLFVLVNLGLPTILARMIDQGV
                     MQQDQRALYFWALMMFIIVLLGVIGRVILSYASGKLTTNMIKDLRNDMYSCLQDYSHS
                     EYEKIGIASLVTRITNDAFVLMQFAEMSLRLGVVTPLMMIFSVVMIFLTSPSLAWIVA
                     VAMPFLVIVVLYVAIKTRPLSEKQQESLDRINQLVRENLTGLRVIRAFAREDFQEERF
                     NKRNDHYSGISKRLFTLTGLTEPLFVQIIIAMIVGIVWFALDPLARGQFKIGDLVAFI
                     EYSFHALFSFLMFANLFTMYPKTAVSSKRIKEVLDMPISIPKNEDGITAFTTRGYLEF
                     DNVTFAYPGETESPVLHNISFKTRPGETIAFIGSTGSGKSSLVNLIPRFYDVTLGRIL
                     VDGIDVRDYQLKALRSKIGFIPQKALLFTGTIEENLKYGKSDASHSELEQATEVSQAK
                     DFITSREKGYQTHLAEAGSNLSGGQKQRLSIARAVVKQPDIYIFDDSFSALDYKTDAE
                     LRRRLKEVTQDATVLIVAQRVGTIMDADQIIVLDQGEIVGRGTHEELLTSNAIYREIA
                     NSQLNKEDMTKEEGD"
     gene            complement(3710..5577)
                     /locus_tag="TVB59_001820"
                     /pseudo
     CDS             complement(3710..5577)
                     /locus_tag="TVB59_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854406.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
     gene            complement(5570..6781)
                     /locus_tag="TVB59_001821"
     CDS             complement(5570..6781)
                     /locus_tag="TVB59_001821"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEL1010675.1"
                     /translation="MTLMTMPSEFQKALPIVKKIKQAGFEAYFVGGSVRDSLLNRPIH
                     DVDIAASCYPEETKAIFLRTIDVGIEHGTVLVLENGSEYEITTFRTEDVYVDYRRPSQ
                     VSFVRSLEEDLKRRDFTVNALALDEDGQVIDIFNGLEDLKHKLLRAVGRPQERFEEDA
                     LRIMRGFRFAASLDFDIEAETFEAMKSHAPLLEKISIERSFIELDKLLMAPKWRKGIL
                     AMVACQAFNYLPGLVGKEEALQKYLKTLAADYVFQDNHQAWAYLLVMLELDQPKAFLK
                     AWKTSNDFQRRVTMMASLYQIRQERQLEKWDIYSFGKDLALLVDDLRQAQGLVSEAKR
                     VESLYQELTIHDKHDIVVNGSYLIRELGMKPGPQLGMLLNQIEQAIVEGRLVNQREHI
                     EAFVRRELLNE"
     gene            complement(6881..7729)
                     /locus_tag="TVB59_001822"
     CDS             complement(6881..7729)
                     /locus_tag="TVB59_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL1010676.1"
                     /translation="MKLAIITDNTAHLPEQLAEHADIFVLDIPVIIDGQSYVEGQNLT
                     IEAFYQSMRESQELPKTSQPSLSELDDLLGRLSTEHYTHVIGLFLASGISGFWQNIQF
                     LIEEHPELTIAFPDSKITSAPLGSMVRNALEWSQQGLSFAEIMDKLEEQIAGTTAFIM
                     VDDLNHLVKGGRLSNGSALLGNLLSIKPILRFDSEGKIVVYEKVRTEKKAMKRLVDIL
                     KELTASGQYEVSIIHARAQDKADILKQLLLDNGYTCPVEEVHFGAVIAAHLGEGAVAF
                     GITPLV"
     gene            complement(7729..8109)
                     /locus_tag="TVB59_001823"
     CDS             complement(7729..8109)
                     /locus_tag="TVB59_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEL1010677.1"
                     /translation="MQLVREKEFVNQYHYDARNLEWEKENGTPETNFEVTFQLINKDV
                     ENKETAIVSVLQFVIVKEEFVISGVISQMVRILGRLVDKPSEFTQEEVESLAAPLLDM
                     VKRLTYEVTEIALDRPGINLEFKS"
BASE COUNT         2487 a         2000 c         1512 g         2349 t
ORIGIN      
        1 tgaattttga tgtcaagctt ttactatgat ctaaagcaaa ttaaaagagc cttggaacga
       61 ttcattccaa gaccctaagc tttttaagac tgactggtct taaattggct atgataaagc
      121 tcataataga agcccttagc agctaatagg ctgtcatgat tcccctgctc gataatctga
      181 ccatctttta gaactaaaat cttatccgcc tcttgaatgg ttgataagcg gtgagcaata
      241 acaaagctag tcctgccaac cattaatcgc ttcatcgcct tttgaatcaa aagctctaaa
      301 cgtgtatcaa cagacgaggt ggcctcatct aggattagca gctttggatc tgctaagaga
      361 gctcgagcaa tggtcagcag ctgcttttgc cccagggaaa tattgctaga ttcctgattc
      421 atcaccatat gatagccacc tggcaatgtc ctaatgaaat gatcaacatt ggcagcctta
      481 gcagcctcaa ttatttgttc atcagtcgcc tctaaatgac caaagcgcaa gttttcctga
      541 atgctgccct caaagagcca agcgtcctgc agcaccatac caaactgacg cctataggct
      601 tgacgtgaca actgacgaat gtcctgacca tcaactgtga tagagccctc attcacatca
      661 taaaaccgca ttaataaatt aatcagggtg gtcttgccgg ctcctgtcgg accaacgata
      721 gctaccatct caccaggctt aacctctaaa ttgaaatttc taatcagagg attgtctgct
      781 gtatagctaa aatcaacctg attaaaggac acctgacctg ttaaatcatg ttctaaatgc
      841 tcttgggcaa tagtcaattc atctgcctca tcaagcactg caaagatacg ttctaaggat
      901 gacttggcac tttgcagtgg accagccagc tgtgttatgg tctgaatagg ctgactgatt
      961 tgccaaatgt actgaacaaa ggcttgcatg tttgttcccg attgtcaggc ggcctgctat
     1021 cacctgtaag ccagcgatta aggcaacaat catgtaaaca gaatctgaaa taaaatgcag
     1081 aactggcatc atgatcccag aaataaagct ggccttaaag cctacttctt gtaatcgctc
     1141 agtgatctgg tgaaattcct cctttgaggc ttcttcacga ccatacagtt ttaaaatatt
     1201 aaagccggtc aaattttcct gcacaaagcc attcatttct cccaaaatat tagcctgcgc
     1261 tttaaaataa ggctgtgatt tttttaaaac aaatcgagaa gcagcatata tcaacgggat
     1321 agcgataatc acaacagagg ctaggggggc attaatatac aagaccatgc caaccaccaa
     1381 aataagggta aaaaaggcgt taacaatctg taaaaaggac tgctgtaagg cattagagac
     1441 tgtctcaaca tcagaggtaa accggcctag catatcgccg aactgatgct tatcaaaata
     1501 agacacaggg atacgattaa ttttttgact gaggtctcga cgaagatcac aaatgcttga
     1561 ttgcacagcc cttgtcataa aatagtttga accataagag cctaactcgt aaacaagggc
     1621 cctaatgata tagagagcta aaagaaaggc gatataggtt ttattaatgc ctgcaccaga
     1681 gactcccttt gctatgtcta ataggtttgc agatagctct gttatcacca agccaagaac
     1741 aaagggctct aagacactca tcacagcact gactattttt aaaataatgg cagttattag
     1801 tgagagccta taggcactaa ggtaggtcca aattcttcta aacacatgct tttcagtcat
     1861 taatccccct cctcttttgt catgtcttcc ttgtttagct gagaattggc aatttcacga
     1921 tagatggcat tgcttgtaag caattcctca tgtgtacctc ggccaacaat ttctccctga
     1981 tccaagacaa tgatttgatc agcatccata atcgtgccca ccctttgagc cacaattaag
     2041 accgttgcat cttgtgtcac ctctttcagc cgtctgcgta attcagcatc tgtcttgtaa
     2101 tctagggcag aaaaggaatc gtcaaagata tagatgtctg gctgcttgac cactgctctg
     2161 gcaatagaca ggcgctgctt ttgccctcct gatagattac tgccggcctc agctagatgg
     2221 gtttgatagc ccttttcacg actggtaata aagtccttcg cttgggaaac ctctgttgcc
     2281 tgctcaagct cactgtggct ggcatctgac ttaccatatt ttaggttttc ctcaatggtt
     2341 cctgtaaata gcagggcttt ttgaggaata aagccgattt tagaacgcag cgcttttaat
     2401 tgataatccc tgacatcaat gccatcaacc aagattctcc ctaaggtcac gtcataaaat
     2461 cgtgggatca gattaaccaa agatgatttt cctgaacctg tcgagccgat aaaagcaatg
     2521 gtctctccag gcctagtctt aaatgagatg ttatgtaaaa ctggactttc cgtttcaccc
     2581 ggataggcaa aggtcacgtt atcaaattct agataaccac gtgttgtgaa cgctgttata
     2641 ccatcttcat ttttaggaat cgaaatcggc atatccagca cttccttgat acgcttgctt
     2701 gacactgctg ttttagggta catggtaaag aggttggcaa acattaaaaa tgaaaaaaga
     2761 gcatgaaagc tatattcgat aaaggccacc aaatcaccaa tcttaaactg cccccttgcc
     2821 aagggatcca aggcaaacca gacgatcccc acaatcatag caatgataat ttgcacaaat
     2881 aagggctctg ttaagcctgt caaggtaaat agtcgctttg agattccaga atagtgatca
     2941 ttgcgcttat tgaagcgctc ttcttgaaag tcttctcttg caaaggctcg aataactctc
     3001 agacctgtca ggttttcacg caccaattgg ttaatacgat caaggctctc ctgctgcttt
     3061 tctgataagg gtcttgtctt tatcgcaaca taaagcacca caataactaa aaaaggcatg
     3121 gcaacagcca caatccaagc caatgatgga ctggttaaaa agatcatcac cactgaaaag
     3181 atcatcatca aaggagttac gacacccagc ctcaaggaca tttcagcaaa ttgcatcaaa
     3241 acaaaggcat catttgttat ccgagtaacc agggaggcta tgccaatttt ttcatattcc
     3301 gaatgcgaat aatcctgcaa gcagctatac atgtcattac gtaaatcctt gatcatgttg
     3361 gtggttagct tacccgaagc ataggataaa atcacccgtc caatgacacc taaaagtacg
     3421 ataataaaca tcatcagagc ccaaaaataa agagcccttt gatcctgctg cataacgcct
     3481 tgatcaatca tacgagccaa tattgttggt agccccagat tgaccagaac aaataacaag
     3541 ccacccacaa tatcgaaaca aatccattta ggtcttgttt ttaaatagga ccaaattaaa
     3601 gccattcatt tcctcccaaa taatagtgat atgaaaagaa gcgcaagcta gcacttcttt
     3661 ttgtctataa ctagtttaac acaaaaatat gaaattgaca cataattaat tattcttcta
     3721 attcgcttag gtaatcaaag cgctcatagg cttcaagcag ctcaagattc cgctgatcca
     3781 gctccttttg atattgtgcc aattggtcgt aatcacttgc cgctctgagc atttgctcct
     3841 caatagtagc tatttgttgc tcgatagcag ctagcttttc ttcaatagct gcccattcct
     3901 ttttctcaag ataggacatt ctctttttag aggtgacctg atggtcagtg ccagcttttt
     3961 gctcactgac agcaggctct atgacctctg cttcaaaagc cttttcatct aaatagtcgc
     4021 tatagttacc atagtattct ctgatagctc catgctcaaa agccaatact tttgttgcaa
     4081 ccttatccaa gaaataccga tcatgactca ctgtaatgac cggaccagca aattgagcta
     4141 aaaaatgctc caacactgtc aaggttgcaa tatccaaatc attggtcggc tcatccagca
     4201 gcaggacgtt gggcttttcg atcaagagct ttagcaaata cagtcttttt tctccccgcc
     4261 tgatagctta gcgattaagg agccatgact agaacgcgga aaaagaaatt gctccaaaag
     4321 ctcactgatg ctagtggtgc caacactggt cttgacctca tctgccacct cctgcaaata
     4381 gctaatcacg cgcttgctgc cgtccatatc cttgatttgc tgtgaaaaat aaccaatacg
     4441 gatcgtctcg ccaatctcta gctgaccagc tgttggtttt aagtcaccag tcatcaagct
     4501 aagcagggtg gtctttccag caccgttagc tccaacaatg ccgatacggt ccttattttg
     4561 aatgatcagg ttaaaatgct caataatggc ctgatcacca taagcaaagg aaacctcctt
     4621 gaaattaatg accttcttgc caatacgact ggcttcaaag gccatatcta attgatctat
     4681 aggcctttcc tgatgaaggt ccttttttaa ctgttcaaag cggttaattc tggcctgctg
     4741 cttggtcgca cgcgcctgtg gctgtgtcct catccaagcc agctcctgtt tatagagctg
     4801 ctttttctta tgcaaatgag ctgcttcgcg ctcgtcttgc tcagccttca gacgcacata
     4861 atcctggtaa ttgccctgat attcagtcac atgagcctta tccaattcaa agatacgtgt
     4921 ggctatacta tccaaaaaat agcgatcatg tgtaataaat agaacagtcc ttttagaggt
     4981 ccttaagtaa tgacttaacc aagcgatggt atcaatatcc aaatgattgg tcggctcatc
     5041 tagcagcaac aaatcactgg ctccaagcaa gacctgagcc agctgtaccc gacgtctcat
     5101 accaccggac aggtcaccca ctctctgatc cagattgaca ataccaagct ttgataagac
     5161 cgtcttaacc tcactttcga tcgaccaaac atctaatcga tccatctcag tcatcacctc
     5221 tgctagcttt tcctgattgc tatctgaata gtcagccatc aacagctcat attggcgaat
     5281 cagctgcatt tcctttaatt ctagggacag aacagtatct aaaacagact gatcatcatc
     5341 aaagtccggc tcctgtgtta aataagatat acgatagtca tttgcctttg aaaaaggtga
     5401 gcggtcacca tcaaagccca ctttttcaga aataacatca agcaaggttg tttttcctgt
     5461 cccattgaca ccaataatgc caatgcgatc accagcatga ataataaagg aaatatcctg
     5521 aaaaacggtc ttatctccaa cagacttcgt cagatgttca acgataaaat cactcattta
     5581 gtagttccct tctaacaaaa gcctcaatgt gttctctttg attgacgaga cgcccctcta
     5641 caatggcctg ctcaatctga tttaaaagca ttcccagctg tggtcctggc ttcattccaa
     5701 gctcacgaat cagataagag ccattgacca caatatcatg cttatcatgg atcgtcagct
     5761 cctgatacaa gctctcaaca cgcttggcct cactgaccaa gccctgtgcc tgtcgtaaat
     5821 cgtcaacgag taaagccaag tccttgccaa acgagtaaat atcccatttt tctagctgtc
     5881 tttcttggcg aatctgataa agagaggcca tcatcgtaac cctacgctga aaatcattag
     5941 aggttttcca agcctttaaa aaggctttag gctgatcaag ctccagcata accagcaaat
     6001 aggcccaagc ctgatgattg tcctgaaaca cataatccgc tgctaaggtt ttcaggtact
     6061 tttgcagggc ttcttccttg cccactaagc ctggcaaata gttaaaggcc tgacatgcca
     6121 ccatagctaa gataccttta cgccattttg gggccattaa aagcttatca agctcaataa
     6181 aagagcgctc aatagaaatc ttctccagca agggagcatg gcttttcatt gcttcaaagg
     6241 tctcagcctc aatatcaaaa tctaagctgg cagcaaaccg aaagcctcgc ataatccgca
     6301 gggcatcctc ctcaaagcgc tcctgaggcc ttccaacagc tcttagaagc ttatgcttta
     6361 ggtcctctaa gccattaaag atatcaataa cctgtccgtc ctcatctaag gcaagagcat
     6421 tgacagtaaa atcccttcgt tttaaatcct cttccaagga ccgaacaaag gatacctgac
     6481 tagggcgcct ataatccaca taaacgtcct cagttcgaaa cgttgtgatc tcatattcac
     6541 tgccattttc taaaacaagc actgtgccat gctcaatccc aacatcaatt gttcttaaga
     6601 aaatagcctt tgtctcctct ggatagcagc tagcagctat atcaacatca tgaataggcc
     6661 tgtttaataa gctatccctc acacttccac caacaaaata ggcctcaaag ccagcctgct
     6721 tgattttttt cactattggt aaagccttct gaaattcaga aggcattgtc attaatgtta
     6781 tcatgtttta atctaccacc taaaagctcc tagagccttg tcatatgctt cccgttaaag
     6841 gctgtcatat caagctcaga ttggtcatgg gcaagcctct ttagacaaga ggcgttatgc
     6901 caaaggcaac agctccttct ccaagatggg ctgcaatcac tgcaccaaaa tgaacctcct
     6961 caacagggca ggtatagcca ttatccaaca agagctgctt taagatatca gccttatcct
     7021 gcgctctagc atggataatt gatacctcgt actgaccact agctgtcaat tcctttaaga
     7081 tatcaaccaa gcgcttcatg gccttttttt ccgttctaac cttttcatag acgacaatct
     7141 ttccttcact atcaaagcga agaattggct tgatgctgag caaatttccc agcaaagcag
     7201 aaccgtttga taagcgtcct cccttgacca aatgattcaa atcatcaacc atgataaagg
     7261 ctgtggttcc agcgatttgc tcttctagct tatccataat ctctgcaaag ctcaagcctt
     7321 gctgagacca ctctaaagca tttctaacca tgctgcctaa tggtgctgag gtgattttac
     7381 tatctggaaa agcaatggtc aactcagggt gctcctcgat gagaaattga atattttgcc
     7441 aaaatcctga aataccacta gccaagaaca agccaatcac atgagtatag tgctcagttg
     7501 acagacgccc tagtaaatca tctaattcag agaggctggg ctgactggtt tttggcagct
     7561 cttgagattc tctcatgctt tggtaaaagg cttcaatggt caggttttgt ccttcgacat
     7621 agctttgacc atctatgatt acaggtatgt ctaatacaaa aatatcggca tgctccgcta
     7681 actgctctgg aaggtgagct gtattatcag ttattattgc taacttcatt aacttttaaa
     7741 ctccaaatta ataccaggac gatccaaggc aatttctgtc acttcgtagg tcaagcgctt
     7801 caccatgtct aataatggag cagccaagga ttcgacctcc tcttgtgtaa attcactagg
     7861 cttatccacc aagcgtccta aaatacgaac catctgtgaa atcacaccac taatcacaaa
     7921 ctcttccttg acaatgacaa attgtaaaac agaaacaata gccgtctctt tattttccac
     7981 atctttatta atcaactgaa aggttacttc aaagtttgtt tccggtgttc cattttcttt
     8041 ttcccattct aaatttctgg cgtcataatg gtactgattg acaaattctt tttcacgtac
     8101 taattgcatg atttcgttct ccttaatggc gatatgaccc attatagcat agatttgacg
     8161 aatattaaag tagacttaaa ccagtatttt ggataatttt tttccagacc ttgtcacttc
     8221 aataaatata aacctgcctt ctatcaacca atcaatctcc tacaacaaaa aaacacccca
     8281 aggtgtactg cccccaaaaa gttgaacgaa taattattga aaggatttag ttctgtattg
     8341 aacagggc
//
LOCUS       DARYNN010000072         8143 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.072, whole genome shotgun sequence.
ACCESSION   DARYNN010000072 DARYNN010000000
VERSION     DARYNN010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8143)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8143)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8143
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.072"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            <1..452
                     /locus_tag="TVB59_001824"
     CDS             <1..452
                     /locus_tag="TVB59_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEL1010678.1"
                     /translation="TFTPDTQDMKFSGVQSGESMKYKLMASDNYREKQERLFKKGLMR
                     RLRLAANIWAIKGNEATTYSLVNDTSIVFTPNLPQNDNEIVTAAQNLYGIVSDQTIFE
                     ILNTVTGVDAEAELERLKEEADKKQSLPEPRLVGDASGQEEPTAEKP"
     gene            412..1857
                     /locus_tag="TVB59_001825"
     CDS             412..1857
                     /locus_tag="TVB59_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HEL1010679.1"
                     /translation="MLVVKKNQQQKSLNYWQKRQEDILSYLDRADLDVFSELQKLYNE
                     QAFELQKELFDFYTKYSEENKMTYQDVVKKLRHEDLSDYVANANKYRKQAEKDPELLK
                     RLNEQYVSARATRMDALNLELVYRAGILKGVLDSAFENHLKKAASYAYKKAMGGRSGT
                     INGPVLEELVRTPFDGYNYSEQLWGNTDNLVKNLQKKLKQGFVRGEHPRAIARDLAKQ
                     FNVANHRAETLIRTDGTMVINNATARRYLDAGLKYYRDLVRLDDRTTEICRKIAKENK
                     RKLLSELKPGINAAPYHFSCRTTLIPDEDELSIEVEPIDDKSTKYFKDVTSDWIDGNG
                     HKPQLSLLNEYVKNGTPYKVDGHNVVLDHSNYEYRVANWLSKKTGLQVDMVPRVNSPE
                     HINTPDYLVDGVPFDLKEITGSGKNVIDGNLRKAKKQATNIIFDITKTPLSFEEIMGQ
                     LEQIYMIDRRGLDISIIKNKDEVLAVLEKEG"
     gene            1888..2076
                     /locus_tag="TVB59_001826"
     CDS             1888..2076
                     /locus_tag="TVB59_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010680.1"
                     /translation="MGVRPSSFFISIIHHPIKTIKEENMFIWQMVLVALGVLVLILIV
                     GIAAIAVKSIIAELKKVG"
     gene            2079..2345
                     /locus_tag="TVB59_001827"
     CDS             2079..2345
                     /locus_tag="TVB59_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010681.1"
                     /translation="MNKRIKKKRKLETAVVMLVAENAMQAEAIKNQNKEIMELKSIVQ
                     RNALATNEEFASVKAATLDNQAAITNIAIDVNYIKKNYKRKWGK"
     gene            2501..3070
                     /locus_tag="TVB59_001828"
     CDS             2501..3070
                     /locus_tag="TVB59_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEL1010682.1"
                     /translation="MAEENVTTETTEQVDTQKEAVEHPKQEHERTFTRADISKMMAAE
                     RTKWESEQSEAIEKARTEGERLAKLSKDERAKEEEQKRLDAIAEREKAVAEREMRIET
                     HSLLVEKGLPLDFIDIVLATTAEEVKTNIDNLQTIFDKAVEKRVNDRLTQKPPRTGNG
                     SVGMTKADIMAIEDDDERMRLIAENRNLF"
     gene            3083..3970
                     /locus_tag="TVB59_001829"
     CDS             3083..3970
                     /locus_tag="TVB59_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HEL1010683.1"
                     /translation="MAEKNLNTMADLGDIKSIDFVNKFSKNINDLLKLLGVTRRETLT
                     NDLKIQTYKWEVTLDQTDPGEGETIPLSKVTRTKDKDYTVKWFKKRRATTAEAIARHG
                     AARAITEADKRIMRELQNGIKDAFFTFLKTKPTKVKGVGLQKALSASWAKLATFNEFE
                     GSPLVSFVSPLDVANYLGDTKVGADASNVFGMTLLKNFLGMQNVIVMPSVPEGKIYST
                     AVENLVFASLNVKGGDLGGLFADFTDETGLIAAARNRQLSNLTYESVFFGANVLFAEI
                     PEGVVEATIEAAAVPGIGG"
     gene            3982..4338
                     /locus_tag="TVB59_001830"
     CDS             3982..4338
                     /locus_tag="TVB59_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HEL1010684.1"
                     /translation="MGDKQLIDDIKLFIGISKGDGAQDELITLAISESKERVLAKLNE
                     YSETEITKIPDRLRFIVRDVAIKRFNRINSEGTVEDSEEGKTFKWDSYLKEYESTLRS
                     AAIGKVYSGKGVARFI"
     gene            4349..4627
                     /locus_tag="TVB59_001831"
     CDS             4349..4627
                     /locus_tag="TVB59_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010685.1"
                     /translation="MIYKDRVILVYVDEQDDFLDKRTVEKPSGKIPCMENTFTKSEQM
                     GLFGKYDLNAFKLHLQGHYDGFSKIIYKGKPRLIKGLAHHKNSTVIYV"
     gene            4624..4968
                     /locus_tag="TVB59_001832"
     CDS             4624..4968
                     /locus_tag="TVB59_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEL1010686.1"
                     /translation="MSLIYRMRGLDRFLRSVERKQKSVRIAVDKELSKSAARIERQAK
                     ILAPVDTGWLRAQIYNEQQQLLHYRVVSPALYSVYIELGTRKMEAQPFLDPALRKEWP
                     VLMANLKKMFKR"
     gene            4972..5331
                     /locus_tag="TVB59_001833"
     CDS             4972..5331
                     /locus_tag="TVB59_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010687.1"
                     /translation="MDYSPETLYLKKVKNRLGVLDIPIYFKLPKSDVLEPFIVVGTNI
                     SDLSKTAQTGAVIDDFSLNIDAFLPGDSRLDAEEIKARMLRLLGRNNQIKAQILVDNS
                     IGREVYRVAINITETLF"
     gene            5343..5942
                     /locus_tag="TVB59_001834"
     CDS             5343..5942
                     /locus_tag="TVB59_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail protein, TP901-1 family"
                     /protein_id="HEL1010688.1"
                     /translation="MANTKEGTTIEITTGKPIVGKKIFYFIQSVDAKKGSKALLPAYR
                     TDGTTTMGGEYIDEQTQQGRVIEKATDEHSIDLTTYFVPTDPSVAVIEEAKKTGKSIK
                     IWEVIADESVKEQIQIPESSGPKKDVYPAKFGYAKIDEIERGTGISDLVEMSYTANIV
                     GALQDGKFPLTKEEIEMLENVYGYQNPGDTTGDYDNITK"
     gene            5996..6451
                     /locus_tag="TVB59_001835"
     CDS             5996..6451
                     /locus_tag="TVB59_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010689.1"
                     /translation="MEFTAAKRNIDIKFDFKTMFKINNKLGTINPETGERNADGVGAL
                     FFNILERNESAIVDLVRLSAGSGKKALTEDEILDAIAEAVDEEGTTEGLFAEIEKEMV
                     DSGFFRAKILKYIENMEKSARYLKAKDDTDATQIQIIEDMIGRMSNAVS"
     gene            6526..6759
                     /locus_tag="TVB59_001836"
     CDS             6526..6759
                     /locus_tag="TVB59_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010690.1"
                     /translation="MEGLEYKQVAERENLSELSLKLRYTLNAKKVDVGKLKYDKHRLT
                     IKRSYQKASRSQADSDSSIVERIQMLNNHFQNR"
     gene            6774..>8143
                     /locus_tag="TVB59_001837"
     CDS             6774..>8143
                     /locus_tag="TVB59_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HEL1010691.1"
                     /translation="MPGTFDGSIFADVGANTKDYEQAMARIVSTTQNAFRKAQDTAVN
                     SSNKMVQIIGQIMAQLANNGESLGKRLGSAYATGLKLSIGEIQRIAASIGEKIPEPIK
                     NGFNKAFSIIQNSVQKLSSAIPHPIKSAFTSATSAVVSFSSKITSAVSAAFNSVSSKA
                     STVADKISSSFGGRITSAVTNLATKLSTGLSNGFSRMSSSAATSLNGISQKFANTSSA
                     GERLKSTVMSIVQAFSLMAVAQKAMHALTGAIGGAVSRVDTMNRFPKTMALFGYSAEQ
                     SKASIDKLSKGIEGLPTPLDSAVKSAQQLAITTGSLDKGTSLALAFNNAMIGYGATTE
                     GAEQALRQFNQSLGSGKIQAEEFNSVSEAAPGLMSKMAEAFGFGKNGVQDLKSALSDG
                     KITAQEFADKMIELNDAQGGFAEMAQSSAGGIRTAWKNVHTAVVKGVAGMISAFDEAA
                     KANGMKT"
BASE COUNT         2732 a         1402 c         1821 g         2188 t
ORIGIN      
        1 ttacttttac gccagataca caagatatga aattttcagg agttcaatct ggtgaatcaa
       61 tgaagtataa gcttatggct tctgacaact atcgcgagaa gcaagagagg ttgttcaaaa
      121 aaggcttaat gcggcgctta cgcttagcag ctaatatctg ggccatcaaa gggaatgaag
      181 caactacata tagccttgta aatgatacga gtatagtttt cacacctaat cttcctcaaa
      241 acgataatga aattgttaca gctgcacaaa atctttatgg cattgttagc gatcagacta
      301 tctttgaaat cttaaacact gtcacaggag tagacgctga agcagagctt gaacgtttga
      361 aagaagaagc tgataaaaag caatctttac cggagcctag attggtaggt gatgctagtg
      421 gtcaagaaga accaacagca gaaaagcctt aattactggc aaaagcgtca agaagatatt
      481 ctaagttatt tagacagagc tgatttagat gtcttttcag aactgcagaa gttatataat
      541 gaacaggctt ttgagttaca aaaggaattg tttgattttt atactaagta ttctgaagag
      601 aacaaaatga cttatcagga tgtcgttaaa aagctacgtc atgaagattt atcagattac
      661 gtagctaatg ctaacaagta tcgcaaacaa gctgagaaag accctgagct gctaaaacga
      721 cttaatgagc agtatgtatc agcaagagct acaaggatgg atgcattaaa tcttgaactt
      781 gtttatcgcg cagggatact aaaaggtgta cttgattcag catttgaaaa tcatttaaaa
      841 aaagctgcct catatgctta taaaaaagca atgggtggac ggtcagggac aatcaatggt
      901 ccagttttag aagaactggt tagaaccccg tttgatggtt ataactactc agaacagttg
      961 tggggcaata ctgacaatct tgtcaagaat ctccaaaaga aattaaaaca aggttttgtt
     1021 cgtggcgagc atcctagagc gatagccaga gatttagcta agcaatttaa tgttgctaat
     1081 cacagggctg aaacactaat cagaactgat ggaactatgg tgattaataa tgctaccgct
     1141 aggcgctact tggatgcagg acttaagtat tatcgtgatt tagttaggct tgatgacagg
     1201 acaactgaga tatgtcgtaa aatcgctaaa gaaaacaaaa gaaagctatt atctgagcta
     1261 aagcctggaa ttaatgcagc accttatcat ttcagctgca gaacaaccct tattcctgat
     1321 gaagatgagc taagcattga agtagaacca attgatgata aaagcactaa gtattttaag
     1381 gatgtcacct cagattggat agatggaaat gggcataaac cacaactgtc actactaaat
     1441 gagtatgtaa aaaatggcac tccttacaaa gtagatggcc ataatgttgt tcttgatcac
     1501 tcgaattatg aatatagagt tgctaattgg ttatctaaaa agacaggatt gcaagttgac
     1561 atggtgccaa gagttaattc ccctgaacat atcaatactc ctgattattt agttgatgga
     1621 gttccttttg atctaaaaga aatcacaggt tcgggtaaaa acgtcattga tggcaatcta
     1681 cgaaaagcaa aaaagcaggc aactaatatc atttttgata taacaaaaac ccctttatca
     1741 tttgaagaga taatggggca gttagaacaa atttatatga tagatcgtag gggtcttgat
     1801 atatcaatta tcaaaaataa agatgaggta ttagctgtat tagaaaaaga aggatgatga
     1861 cccaccgcct ccacagtaaa ctgcttcgtg ggcgttagac catcatcctt ctttatctca
     1921 attatacatc accctattaa aactatcaag gaggaaaata tgtttatttg gcaaatggta
     1981 ttagtggcac taggtgtatt ggtgctcata ttgattgttg gcattgcagc aatagcggtt
     2041 aagtcaatta ttgcagaatt gaaaaaggta ggataaacat gaataagcgc attaagaaaa
     2101 aacgtaagtt ggaaacagcg gttgtgatgc ttgttgcaga gaatgccatg caagcagaag
     2161 caattaaaaa tcaaaacaaa gaaatcatgg agttgaaatc aattgttcag cggaacgctc
     2221 tggcaacaaa cgaagagttt gcgtctgtta aagctgctac tttagataat caagcagcta
     2281 ttacaaacat tgcaattgat gttaactaca ttaagaaaaa ttataagcgt aagtggggaa
     2341 aataaatttt aaacgaattc gaccccttta gaaatcaaag tcgtagcaat acggctttta
     2401 ttgtgtccaa actttgttga tgacactaaa agctacactg tttcgtcgca ggacgtaaag
     2461 ctagactatc ggttggtggc gtaaccacta ggagaaagtt atggcagaag agaatgtaac
     2521 aacagaaaca actgagcaag tcgacactca aaaagaagct gttgaacatc ctaagcagga
     2581 acatgagcga acttttactc gcgcagacat ctcaaaaatg atggctgccg aacgcactaa
     2641 atgggaatct gaacaatcag aagctattga aaaagctcgt acagagggtg aacgtttggc
     2701 caagttgtca aaagatgagc gcgctaaaga ggaggaacaa aaacgtctag atgctatcgc
     2761 agagcgtgaa aaagcagtag cagagcgcga gatgcgcatt gagacgcatt ccctgcttgt
     2821 ggagaaagga ttgccattgg attttattga tattgtttta gccactactg cagaagaggt
     2881 taagaccaat attgataatt tacaaactat ttttgataaa gctgttgaaa aacgtgttaa
     2941 cgatcgttta acccagaagc caccacgaac tggaaatggc tcggtcggca tgaccaaggc
     3001 tgacatcatg gcaatagagg atgatgacga acgtatgcgt ttaattgctg agaatcgtaa
     3061 cttattttaa gagaggaata ttatggctga aaaaaattta aacactatgg cggacttagg
     3121 agatattaaa tcaattgatt ttgttaacaa gttttccaaa aatattaatg atttactaaa
     3181 attgctaggg gtcactcgtc gtgaaacatt aactaacgat ctaaaaattc agacctataa
     3241 gtgggaagtg actttagatc aaactgatcc tggagaaggg gaaaccatcc ctctgtctaa
     3301 ggttactcga actaaagata aagactatac agtgaagtgg ttcaagaaac gtcgtgcaac
     3361 tacagctgag gcaattgctc gccatggcgc agctcgtgct attactgaag cagataagcg
     3421 cattatgcgt gagcttcaga atggaattaa ggatgcattc tttacattcc tcaaaacaaa
     3481 accaacaaaa gttaaaggcg ttggccttca aaaagcgctg tctgcatcat gggctaagct
     3541 agctactttt aatgagtttg agggttcccc gcttgtttct tttgtctctc ctttagacgt
     3601 agccaactat cttggagata ctaaagtagg tgcggatgcc tctaatgttt ttggaatgac
     3661 attgcttaag aactttttgg gtatgcaaaa tgtgattgtt atgccatctg tgccagaggg
     3721 taaaatctac tcaacggctg tagagaatct agtttttgcg tctttaaatg ttaaaggcgg
     3781 agacttgggc ggcttgtttg ctgattttac tgatgagaca ggtttaattg ctgcagctcg
     3841 taatcgtcag ctttctaatc ttacctatga atctgttttc tttggggcga atgtgctgtt
     3901 tgctgaaatt cctgaagggg ttgtagaggc aacaatcgaa gctgctgctg tacccggcat
     3961 tggtggttaa aggctattta tatgggcgat aaacaactta ttgacgatat caaactcttt
     4021 ataggtattt ccaaggggga tggtgcgcaa gatgagctca tcacccttgc tatatctgaa
     4081 agtaaagagc gtgtgctagc taaacttaat gaatactcag agactgaaat taccaaaatt
     4141 cctgatagat tgaggtttat tgtccgtgat gttgccatta aacggtttaa taggattaat
     4201 tcagaaggaa ccgttgagga tagcgaagaa ggaaagactt ttaagtggga cagttacctt
     4261 aaagagtatg aatcaacact cagaagcgct gctattggga aggtatattc aggcaaaggg
     4321 gtagcaagat ttatttagga gatacacaat gatctataaa gatagagtaa tcttagtgta
     4381 tgtcgatgag caggacgatt ttctagataa aagaactgtt gaaaaaccta gcgggaaaat
     4441 cccctgcatg gaaaatactt tcacaaaatc tgaacagatg gggctatttg gtaaatatga
     4501 tttgaatgct tttaagttgc acttgcaagg ccattacgac ggctttagca agattatcta
     4561 caagggaaaa ccgaggttga taaagggact agcacaccat aaaaatagca cggttattta
     4621 tgtatgagtc ttatttatcg gatgagaggc ttagataggt ttttacgcag cgttgagcgc
     4681 aagcagaagt cagtacgaat cgctgtagat aaagagctta gcaaatcagc tgctagaatt
     4741 gagagacagg ctaaaatact agccccggtt gatactggat ggctgagagc tcaaatctac
     4801 aacgagcaac aacaactctt acactataga gtggtttctc ctgctttata ttctgtttat
     4861 attgaattag gtactcgtaa aatggaagct caaccgtttt tagaccctgc tctgagaaaa
     4921 gaatggcctg tgctaatggc taatctcaaa aaaatgttta agaggtgatg catggattac
     4981 tcaccagaaa cactatattt aaaaaaggta aaaaatagat tgggagtttt ggacatacca
     5041 atctatttta aattgcctaa atcagacgtt ttagagcctt ttattgttgt gggtacaaat
     5101 atatcagact tgtcaaaaac agctcaaact ggagcagtta ttgacgattt tagcctgaat
     5161 atcgatgctt tcttacctgg cgatagtcgt ttggatgcag aagagataaa agctcgcatg
     5221 cttagactgc ttgggcggaa taaccaaata aaggctcaga ttttggtaga taattcaata
     5281 ggacgagaag tctatagagt tgctatcaac attacagaaa cactatttta aaggagacct
     5341 aaatggcaaa cactaaagaa ggaacaacta ttgaaattac aacaggtaaa ccgattgtag
     5401 ggaaaaagat tttttatttc atccaatcag ttgacgctaa aaaagggagt aaggctttgc
     5461 tgccagccta tcgtaccgat ggtactacaa ccatgggcgg tgaatacatt gatgagcaaa
     5521 cccaacaagg ccgcgttatt gagaaggcta cggatgaaca ctctattgat ttgacaacgt
     5581 actttgtacc gacagatcca tctgttgctg tcatcgagga agctaagaaa acgggtaaat
     5641 ctatcaaaat ttgggaagtt attgccgacg aaagcgtcaa agaacaaatc caaattcctg
     5701 aatcgagtgg tcccaagaaa gatgtttacc ctgctaagtt tgggtacgcc aagattgacg
     5761 aaatcgaacg tggtactggt atttcagact tagtagaaat gtcctacacc gctaacattg
     5821 taggggcctt acaagatggt aaattccctc tcacgaaaga agaaattgaa atgctagaaa
     5881 atgtatacgg ctatcaaaat ccgggtgata ctactggcga ctacgataat atcactaagt
     5941 agtacacagg ggcggcgact gctgccccat tttgatttaa aaaggagata aaataatgga
     6001 atttacagca gcgaaacgaa atatcgatat taaatttgat tttaaaacta tgtttaagat
     6061 caataataaa ctaggaacaa ttaacccaga aacaggagag cgcaatgcag atggtgttgg
     6121 tgctttgttt ttcaatatct tagagcgtaa tgaaagcgcc attgttgacc ttgtgcgttt
     6181 atctgcggga agcggaaaaa aagcgctaac tgaagatgaa attctagatg caattgcaga
     6241 agctgttgat gaagaaggaa caacagaagg gttgtttgct gaaatagaga aagaaatggt
     6301 tgattctggt tttttcagag cgaagatttt gaaatatatc gaaaacatgg agaaatcagc
     6361 tcgctatctc aaagcgaagg acgatacgga cgcaactcaa atccaaatta tcgaagacat
     6421 gattggaaga atgagcaacg cagtatctta gtaaattgcg cacggttagg gctcacagac
     6481 attgatacta tctataaatg tactaagtgg gagctagagg ctattatgga ggggcttgag
     6541 tataagcagg ttgctgagcg cgagaacctc tctgaattgt ctctaaaact tagatataca
     6601 ttaaatgcta aaaaggttga tgtaggtaag ctcaaatatg ataagcatag gctaactatc
     6661 aaaagatcgt atcaaaaagc tagccgtagc caagccgata gtgatagcag tattgttgag
     6721 agaatacaaa tgcttaataa tcattttcaa aatagataga taaggaggag tagatgccag
     6781 gaacatttga tggttctatt ttcgctgatg ttggtgccaa cacaaaggac tatgagcagg
     6841 ccatggctcg tattgttagt acgactcaga atgctttcag aaaagcccaa gatacagcgg
     6901 ttaacagtag taataaaatg gttcaaatca ttggacaaat catggcccaa ttagcgaaca
     6961 acggcgaatc gctcggaaag agacttggtt ccgcctacgc tactggttta aaactgagca
     7021 ttggtgaaat tcaacgtata gcagcttcca ttggcgaaaa aattcccgaa cccataaaga
     7081 atggtttcaa taaagctttt tcaattatcc aaaatagcgt acagaagtta tctagcgcca
     7141 tccctcaccc cataaaatcc gcattcacaa gtgcaacaag tgcagtagtt agcttttcgt
     7201 ctaagatcac aagtgccgtc tcagcagctt tcaactctgt tagttctaaa gcgagtactg
     7261 ttgcagataa aatcagtagt agttttgggg gtagaatcac ttcagcggtt actaatttag
     7321 cgactaagtt aagtacaggt cttagcaatg gttttagcag aatgtctagt tctgcggcta
     7381 cttccttgaa tggaatcagc cagaaattcg ccaacacctc ttctgctgga gagagactca
     7441 aaagtacagt gatgagcatc gtgcaggcct ttagtttaat ggctgttgct caaaaagcta
     7501 tgcacgctct tactggggca ataggcgggg cggttagtcg ggttgatacc atgaaccgct
     7561 ttccgaaaac gatggcacta tttgggtatt ctgctgaaca atctaaggca tcaattgata
     7621 agttgtcaaa aggaattgaa ggtctgccaa ctcccctaga tagcgctgtg aaaagtgctc
     7681 agcagctcgc cataaccaca ggaagtttag ataaaggaac tagtttagcc ctcgccttca
     7741 ataatgcaat gatcggttac ggtgcaacaa ctgaaggggc tgagcaagca ctcaggcagt
     7801 ttaaccagtc gttggggtct ggaaaaattc aagctgaaga gtttaactct gtatcagaag
     7861 ctgcgccggg tttaatgtct aaaatggcgg aagccttcgg ttttggtaaa aatggcgtac
     7921 aagatttaaa atcagcctta tctgatggca aaatcactgc acaagagttc gcagataaaa
     7981 tgattgagct taacgatgcc caaggcggat ttgcagagat ggcccaatca tcggctggtg
     8041 gaatccgaac tgcgtggaag aacgtacata ccgccgttgt aaaaggcgta gcaggtatga
     8101 tttcagcctt tgatgaagcg gctaaagcta atggtatgaa gac
//
LOCUS       DARYNN010000073         8115 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.073, whole genome shotgun sequence.
ACCESSION   DARYNN010000073 DARYNN010000000
VERSION     DARYNN010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8115)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8115)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8115
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.073"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(2..2005)
                     /locus_tag="TVB59_001838"
     CDS             complement(2..2005)
                     /locus_tag="TVB59_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter Kup"
                     /protein_id="HEL1010692.1"
                     /translation="MSNAHHDAFDKATKAGFIIALGIVYGDIGTSPLYTMQSLVDNQG
                     GLSQVSEAFILGSVSLIIWTLTLVTTIKYVLIALKADNHHEGGIFSLFTLVRRMSRWL
                     IIPAMLGGATLLSDGALTPAVTVTSAIEGLKAVPELSSIYQNQTNVILTTLLILMVLF
                     GLQRFGTGVIGKLFGPVMLVWFSVLGISGLLNSLQHLEILKAINPYYALHLLVSPENH
                     RGIFILGSIFLATTGAEALYSDLGHVGRGNIYASWPFVKVCIILSYCGQAAWILAHKD
                     SGIALNPFFASVPEGLRVYLVILATLAAIIASQALISGSFTLVSEAMRLKIFPLFKIT
                     YPGANLGQLYIPVINWSLFAVTSCTVLYFRTSAHMEAAYGLAITITMLMTTILLAYYL
                     IKEGVKPLLASLLMAFFAFIEFIFFLASAVKFMHGGYVVVVLALAIVFVMVIWHAGTM
                     IVAKYVKSLSLNDYKHQIKLLRDDLRFDLYQTNVVYLTNRMKKDLIDRSILYSILDKR
                     PKRAQVYWFVNVRVTDEPYTATYKVDMLETDYIVCVELYLGFRMPQTVPRYLRTIVQD
                     LMESGRLPKQAQDYTITPGREVGDFRFVIIEERVSHARQLSTLERFVMQTKASIKHVT
                     ASPMRWFGLQYSEATVEVVPLLLSDVLKLPIKEIKACTKDEKA"
     gene            complement(2132..3748)
                     /locus_tag="TVB59_001839"
     CDS             complement(2132..3748)
                     /locus_tag="TVB59_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL1010693.1"
                     /translation="MKFTAFNLSEDIQSAVVTAGFEKASPIQELTIPLALEGRDVIGQ
                     AQTGTGKTAAFGLPTLNKIRTADNTIQALVIAPTRELAVQSQEELFRFGRDKGVKVRS
                     VYGGSSIEKQIKALKSGAHVVVGTPGRLLDLIKRKALRLDHVETLILDEADECLNMGF
                     LEDIEAIISRVPDDRQTLLFSATMPAPIKEIGVKFMKDPEHVQVKNKELTNVNVDQYY
                     VRVKEQEKFDTMTRLMDVQQPELSIVFGRTKRRVDEITRGLKLRGFRAEGIHGDLDQN
                     KRLRVIRDFKNDQLDILVATDVAARGLDISGVTHVYNYDITQDPESYVHRIGRTGRAG
                     KSGESITFVSPNEMGYLTMIEHLTKKRMKPLKPATAEEAFQAKKKVALKKIERDFADD
                     AIRSNFEKFKGDAMKLAAEFTPEELALYILSLTVQDPDTLPEVEIAREKPLPFKYVGG
                     GHGNKNGKTGRGNRSRSGRDNRRGGYRHEKRNVYDGDRRPRRDKRDSHDSSGSYDFKR
                     KQKRSNKDLHKKGKAVEAKTSGFIIRHKGN"
     gene            complement(4164..5708)
                     /locus_tag="TVB59_001840"
     CDS             complement(4164..5708)
                     /locus_tag="TVB59_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEL1010694.1"
                     /translation="MSITEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKSGQFAKSDWMDFEKQRGISVTSSVMQFDYAGKRINILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRNIPVFTFINKLDRDGREPLELLEELEEVLG
                     IASYPMNWPIGMGRAFEGLYDLHNKRLELYKGEQRFADLEEGARIFASNPFYEQVLED
                     IELLEEAGNDFSEQAILDGQLTPVFFGSALTNFGVQTFLDTFLAFAPEPHGHKTTTDQ
                     MIDPLNQDFSGFVFKIQANMDPKHRDRIAFVRIVSGEFQKGMAVKLSRTGKSVKLSNV
                     TQFMAESRENVQNAVAGDIIGVYDTGTYQVGDTLSVSKNLFEFEPLPTFTPEIFMKVA
                     PKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VIMTPMGKKTVRWISEEDLDQRMSSSRNILARDRFDQPVFLFENDFALRWFADKYPDV
                     KLEAKM"
     gene            complement(5877..6572)
                     /locus_tag="TVB59_001841"
     CDS             complement(5877..6572)
                     /locus_tag="TVB59_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEL1010695.1"
                     /translation="MNFFAIEPIGLPHVSLLFYLLSVMIAPFLVFMTLQLYQLKSYRY
                     IFLGLQLVQLVGLYSWYALRGFPLTEALPLYHCRMAMLAIFFLPDRSSLKQLFMVLGI
                     GGTFLALLSPDLYPYQLWHVANISFYLGHYALLVNGLVYLLRFYNPSQLKPVLVCRYL
                     ATINFVLVLINLATKGNYGFVMDIPIIHTHHLLMNFVIVTMGLTGLIKLIELIYVRFS
                     EANQLELKLSKER"
     gene            complement(6656..8041)
                     /locus_tag="TVB59_001842"
     CDS             complement(6656..8041)
                     /locus_tag="TVB59_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEL1010696.1"
                     /translation="MKLTLHEVARVVDAQNSLSDLDDVPLNQIEFDSRNITKGDLFLP
                     LQGERDGHDFIDLAFENGAVATFSERAISGRPYILVENCLAAFQKLAQYYIDKLRVDV
                     IAVTGSNGKTSTKDMIEAVLAKAYKTYKTQGNYNNDIGLPYTVLHMPEDTEKIVLEMG
                     QDHMGDIQLLSRIARPHIALLTLIGEAHLAYFGSREKIAEGKMQIVDGMDSNGILIAP
                     GDPILDPYLPDSQMVIRFGDHQELVVEDIKECKDSLTFRTNVLPRPVTLPLTGKYNAT
                     NAMIAAYVGKLLAVPDEDIIEALETVKLTRHRTEWVKAANGADLLADVYNANPTAMRL
                     ILETFAAIPANPNGKKIAVLADMKELGADSVALHSQLITSLDPKRIDQLVFYGDDIQA
                     LAKLASQDYPSGRVSFFKKNNREDQYEDMCQYLLTILEPNDQMLLKGSHSMLLANVVD
                     RLTAPHAGKSS"
BASE COUNT         2468 a         1932 c         1519 g         2196 t
ORIGIN      
        1 cctaggcctt ttcatctttt gtacacgctt tgatttcctt gattggaagc tttaagacat
       61 ctgataagag taaaggaaca acctcaactg ttgcctcaga atattgcagg ccaaaccaac
      121 gcatagggct tgctgtcaca tgcttgatac tagcctttgt ctgcatgaca aaacgttcca
      181 gagtactcag ctgccttgca tgcgacacgc gctcctcaat gatcacaaac ctaaagtcac
      241 caacctctcg acctggtgta atcgtgtaat cctgagcttg cttaggcaga cgaccactct
      301 ccatcaaatc ctgaacaatc gttctaaggt aacgtggaac agtctgtggc attctaaagc
      361 caaggtagag ctctacacaa acgatatagt ctgtttctaa catatccacc ttgtaggtcg
      421 ccgtataagg ctcatctgtc acacgaacat taacaaacca ataaacctgt gcgcgcttag
      481 gacgcttatc taaaatagaa tacaggattg agcgatcaat cagatctttt ttcatgcgat
      541 tggtcaagta aacaacattg gtctgataca aatcaaagcg aagatcatct ctgaggagct
      601 tgatttgatg cttgtaatca tttaggctca aggacttaac atatttagca acaatcatgg
      661 ttccagcatg ccaaatcacc ataacaaaga caatggcaag agctaaaaca acaacaacat
      721 agcccccatg cataaactta actgcagacg ctaaaaagaa aataaactca ataaaggcaa
      781 aaaaagccat gagcagacta gccaggagcg gctttacccc ctccttaata aggtaatagg
      841 ctaagagaat cgttgtcatc agcatggtaa tcgtgatggc aaggccatag gcagcctcca
      901 tatgcgctga tgttctaaaa tacagcaccg tacaagacgt taccgcaaac aagctccagt
      961 taatgacagg gatgtatagt tggcctaggt tggcacctgg ataggtaatc ttaaacaacg
     1021 gaaaaatctt caagcgcata gcctcagaaa ccaaggtaaa ggaacctgag attaaagcct
     1081 gcgaagcaat aatggctgct agagttgcta gaataacaag ataaacccgt aatccctctg
     1141 gaacactagc aaagaaggga ttaagcgcaa tgcctgagtc cttatgcgct aaaatccaag
     1201 ctgcctgacc acaataggat aagatgatac aaaccttaac aaagggccag ctagcataaa
     1261 tatttcctcg accgacatga cctaaatcag aataaagagc ttcagcacca gttgtcgcta
     1321 aaaaaataga gcctaaaatg aaaatacccc gatgattttc cggactaacc aataagtgca
     1381 gcgcataata gggattgata gcctttagga tttccaaatg ctgtaagcta ttcaagagac
     1441 cactgatccc caaaacgcta aaccaaacca gcatgactgg cccaaataat ttaccaataa
     1501 cacccgttcc aaagcgctgc aggccaaaca agaccatcaa tatcagcaag gtcgttagga
     1561 tcacattggt ctgattctgg taaatactgc tgagctcagg aacagccttt aagccttcaa
     1621 tggctgatgt gaccgtaaca gctggtgtca aggcaccatc tgataagagc gttgctcccc
     1681 caagcatagc tggaatgatt aaccaccttg acatccttct aactaaggta aagagtgaaa
     1741 aaatccctcc ctcatgatga ttatcagcct ttaaagcaat caaaacatac ttgattgtcg
     1801 ttaccaaggt tagagtccaa ataatcaagg atactgagcc taaaataaaa gcttcagaca
     1861 cctgtgaaag gccgccttga ttgtcaacca acgactgcat ggtatacagt ggacttgtgc
     1921 caatatcacc atagacaatt cctagtgcaa taataaaacc tgcctttgtt gctttatcaa
     1981 aggcatcatg atgggcatta gacatcccaa tgttcctcct aagacttaat catgccaaat
     2041 ggactgagac cattatagca aaatctataa caaaatcaat attttcagaa aattaaaaag
     2101 agagctgaca atcatcagct ctcttgaaac tttagttccc tttatgacgg ataataaatc
     2161 cagacgtctt agcttcgaca gccttgccct tcttgtgcag gtccttgtta gagcgttttt
     2221 gctttcgctt aaagtcatag ctaccactgc tatcatgact gtcacgttta tcacgccttg
     2281 gacggcggtc accatcataa acatttcttt tctcatgacg atagccacct cgacggttat
     2341 cacgaccgct acgactacga ttgccacgac ctgtcttgcc atttttattg ccatgaccac
     2401 caccaacata cttaaacggt aatggctttt cacgcgctat ctcaacctct ggtaaggtat
     2461 ctggatcttg gacggtcaag ctaaggatat agagcgctag ctcctctggg gtaaactctg
     2521 ctgccaattt catcgcatcg cccttaaatt tctcaaagtt tgagcgaata gcatcatctg
     2581 caaaatcacg ctcaattttt ttgagggcaa cctttttctt agcctgaaag gcttcctctg
     2641 ccgtagctgg cttgagtggc ttcatgcgct tcttagtcag gtgctcaatc atggtcagat
     2701 agcccatctc atttggtgag acaaaggtaa tggattcccc tgacttacct gcacgaccgg
     2761 tccggccaat acggtgcaca tagctttctg gatcctgtgt aatatcgtaa ttgtacacat
     2821 gagtaacgcc tgaaatatca agcccacgcg cagcaacatc ggttgccact aaaatatcaa
     2881 gttgatcatt tttaaagtcg cgtatgacac gaaggcgctt attttggtca aggtcaccat
     2941 gtatcccttc tgcgcgaaaa ccacgcaatt ttaagccgcg cgtgatttca tcaacacgac
     3001 gctttgtgcg accaaataca attgatagct ctggctgctg aacgtccatc agacgtgtca
     3061 tggtatcaaa tttttcttgc tccttaacac gcacatagta ttgatcaaca ttcacatttg
     3121 ttaattcctt gtttttaacc tgaacatgct caggatcctt cataaacttg acaccaattt
     3181 ccttgattgg agctggcatt gttgctgaaa ataacagggt ttgacgatcg tcagggacac
     3241 gactaataat cgcttcaatg tcctctaaaa atcccatatt caagcattca tcagcttcat
     3301 ctaaaatgag tgtctcaaca tggtctagcc tcaaggcctt acgcttaatc aaatctaaca
     3361 gacgtcctgg cgttccaaca acgacatgcg ccccagactt tagggcctta atttgcttct
     3421 caatgcttga gccaccatat actgagcgaa ccttgacgcc tttatcacga ccaaaacgga
     3481 acagctcttc ctgactttgg acagccagct cacgcgtcgg agcaatcacc aatgcctgaa
     3541 tggtgttatc ggctgtacga atcttattca gagttggtag accaaaggct gctgtttttc
     3601 ctgttcctgt ctgagcctgt ccgataacat ctcgtccctc caaggctaac ggaatggtca
     3661 gctcctgaat aggagaggct ttttcaaagc ctgctgtaac aacagctgac tgaatatctt
     3721 ctgataagtt aaatgctgta aatttcaatt gtttctcttt tctaaaaagg cagtgcgaag
     3781 ctgccttata aaccttttaa tattgtcgtt cgattaacaa cctatttagt gtaacataat
     3841 taatattaaa aagataggaa ataagccatg aaagtgtttt tatctcaaaa tgattaacac
     3901 tatcaggcag ctaaattgat aaaagcgtca ctccttattg ctgattggct aacagcctca
     3961 aaaaggcctc gtcggacttg cttacctatg ctttttatct actctgctaa aaagactcgg
     4021 cacagagacg agccttcgcg attccatcac caatcttcaa agacagcaat taggattcct
     4081 gaaagctcct tatgccaata gcctgccttt tcttagcagc agaagtgcaa aaacggacta
     4141 ggttccccta atccgcttag ctgctacatt tttgcttcta gcttaacatc tgggtattta
     4201 tctgcaaacc aacgaagcgc aaagtcattt tcaaagagaa aaacaggctg atcaaagcga
     4261 tcccttgcca aaatgtttcg gcttgaggac atgcgttggt ccaaatcctc ctctgagatc
     4321 caacgaacag tctttttgcc cattggtgtc atgatgacct ctgcattgta ctcaccctcc
     4381 atacggtgct tgaaaacctc aaactgcagc tgaccaactg cgcccagcat gtattcacct
     4441 gtctgataat tcttataaag ctgaacagcc ccctcctgta caagctgctc aatacctttg
     4501 tggaaagatt tttgcttcat gacattctta ggtgcaacct tcataaaaat ctctggggta
     4561 aaggtcggca atggctcaaa ttcaaacagg tttttactaa cgctcaaggt atctccaacc
     4621 tgataagtcc ctgtatcgta gaccccaata atatcaccgg caactgcatt ttggacattt
     4681 tcacgagact cagccataaa ctgagtaaca tttgatagct taacgctttt acctgtacga
     4741 gacagcttta cagccattcc cttttgaaac tctccagaga caatacgcac aaaggcaatg
     4801 cggtcacgat gcttagggtc catgttagcc tgaatcttaa agacaaagcc tgaaaaatcc
     4861 tgattgaggg gatcaatcat ctggtccgtt gtcgtcttat gcccatgagg ctctggtgca
     4921 aaggctaaaa aggtatctaa aaaggtttgt accccaaaat ttgttaaggc agagccaaag
     4981 aataccggag tcagctgacc atctaaaata gcctgctctg aaaagtcatt acctgcctcc
     5041 tccaagagct caatatcttc aagcacctgc tcataaaaag ggttgctggc aaaaatcctt
     5101 gccccctcct ctaaatcagc aaacctctgc tcccccttat aaagctccaa gcgtttgttg
     5161 tgcaaatcat acagaccttc aaaggctcgt cccataccaa ttggccagtt catggggtaa
     5221 gaagcaatcc caagaacctc ttctagctcc tccaacaact ccaaaggctc acgtccatca
     5281 cgatctaatt tattaataaa cgtaaaaaca ggtatgttac gatgcttaac aacctcaaag
     5341 agctttttcg tctgtgcttc gatcccttta gccgaatcaa caaccatcac agcagcatca
     5401 actgccatta aggtacgata agtatcctct gaaaagtcct cgtgaccagg tgtatctaaa
     5461 atattgatac gcttaccagc ataatcaaac tgcatgactg atgatgtgac tgaaatccca
     5521 cgttgctttt caaaatccat ccaatctgac ttagcaaatt gaccagattt ttttccttta
     5581 acggtcccag cctcacgaat ctcaccacca aaataaagta actgttctgt aatagttgtt
     5641 ttaccagcat ctgggtgact gataatcgca aaggttcgac gctttttaat ttcttctgta
     5701 attgacattc ttttttcctt atttgttcac attgcagagc aagactctga ttaatagctt
     5761 caagtcacac gtcacagtta tgtctacatg atctcactcc taaatactga tatgataaaa
     5821 agagctgcta gagcagctcc tttattatag ctgattcgaa gcgctttttc aacgccctat
     5881 ctttctttag agagcttcag ctctaactga ttggcctcac taaatctcac atagataagt
     5941 tcaatcagct taattaaacc agtcaacccc attgtcacaa tgacaaaatt cataagcagg
     6001 tgatgcgtat gaataatcgg aatatccatc acaaagccgt aatttccctt tgttgccaaa
     6061 ttgatcaata ctaaaacaaa attaatggtt gccaagtaac ggcaaacaag gactggcttt
     6121 agctgacttg gattgtaaaa ccgcagcagg taaaccaagc cattgaccaa aagagcataa
     6181 tgccccaggt aaaaagaaat attagccaca tgccatagct gataagggta taaatcaggt
     6241 gataacaggg ccaaaaaggt cccaccaatc cctaaaacca taaaaagctg ctttaagcta
     6301 ctgcgatccg gtaagaaaaa gatagctagc atggccattc ggcaatggta aagcggcaaa
     6361 gcctctgtca acggaaagcc tcgcaaggca taccagctat acaaaccaac caattggacc
     6421 aactgaagcc ctaagaagat atagcgatac gactttagct gatagagctg cagggtcata
     6481 aaaaccaaaa acggcgctat catcaccgac aatagataaa atagcaagga cacatgcggt
     6541 agcccaatag gttcaattgc aaaaaaattc ataaacatcc ctttctacat tttttcatta
     6601 taccttaatc ttaatgagag gacaagatgt ttcatgtgtt ttttctgaaa aagtgttagg
     6661 aggacttccc agcatgagga gctgtcaggc gatcaaccac atttgctagc agcatggagt
     6721 ggctgccctt tagcagcatc tggtcattag gctcaagaat agtcaacagg tactggcaca
     6781 tgtcctcgta ttgatcctct cgattattct ttttaaagaa gctaactctg ccacttggat
     6841 aatcttgact agctagcttg gccaaggctt gaatatcatc accgtaaaag accaattgat
     6901 caatacgctt gggatctaag ctggtaatca gctgagaatg caaagcaact gagtcagcac
     6961 ctaattcctt catatcagct aaaacagcta tttttttgcc attagggttg gccggaatgg
     7021 cagcaaaggt ttccaaaatt aaccgcatag cagttggatt ggcattgtac acatctgcca
     7081 aaaggtcggc gccattagcc gccttgaccc actcggttcg gtggcgtgtc agcttgacgg
     7141 tttctaaagc ttctataata tcctcatcag gcacagccaa gagtttacca acataagctg
     7201 ctatcatagc attggttgca ttgtattttc cagttaaggg aagagtgacc ggtcttggta
     7261 agacattagt cctaaaggtc aaggagtcct tgcactcttt gatatcctca accaccagct
     7321 cttgatgatc gccaaagcga atgaccatct gactatccgg caaatatgga tcaaggatag
     7381 gatcaccagg agcaattaaa atcccgttag agtccatccc atcaacgatt tgcattttcc
     7441 cttcggcaat cttctcgcga gagccaaagt aggctaagtg agcctcacca ataagggtta
     7501 gcaatgcaat atgaggtctg gcaattctag agagcagctg aatgtctccc atatgatcct
     7561 gccccatctc taaaacaatc ttctcagtat cctctggcat gtgaagcacc gtataaggca
     7621 agccaatgtc attattataa ttgccctggg ttttgtaggt cttataagct tttgccagga
     7681 ccgcttcaat catatccttg gttgatgttt taccgtttga gcctgttaca gcaatgacat
     7741 cgacacgtag cttatcaata taatactggg ctaatttttg aaaggcagcc aagcaattct
     7801 caactagtat atagggtctg ccactgattg ctctttctga aaaggtagct acggccccat
     7861 tttcaaaggc taagtcaata aaatcatggc catctcgctc accctgtagc ggtaaaaaaa
     7921 gatcaccttt tgtgatgttt ctactgtcaa attcaatctg attcagagga acgtcgtcta
     7981 aatcagaaag actattttga gcatcaacaa ctcttgccac ttcatgtaat gttaatttca
     8041 tcttattttt cctcttaaaa cactggtttt taaagctttg cttatattat agcataacat
     8101 attaggaata ttctt
//
LOCUS       DARYNN010000074         7716 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.074, whole genome shotgun sequence.
ACCESSION   DARYNN010000074 DARYNN010000000
VERSION     DARYNN010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7716)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7716)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7716
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.074"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            <1..405
                     /locus_tag="TVB59_001843"
     CDS             <1..405
                     /locus_tag="TVB59_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEL1010697.1"
                     /translation="GRGFYKKYMNAYGQVARLHSQQWYTDVVHLPVEFPMSADGHRPV
                     SERYRTLSDKEIREGFLSIGKTPELVSGSQVERLRKIINLYDLPVVVPIDEAVTQAEE
                     QIRTNREAVSKRIIEQYKEPSLKEKIKFISEF"
     gene            414..1085
                     /locus_tag="TVB59_001844"
     CDS             414..1085
                     /locus_tag="TVB59_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1010698.1"
                     /translation="MISFKNISKTYQVGDQEVKVLDDVSFTIEKGRFTVILGPSGSGK
                     STLLNLLGGMDRASKGTFIFEGKDITALNDKALSDYRKEVVGFVFQFYNLIPSLTALE
                     NISIAAQLTGNTAQSEVLLDKVGLSHRKNNFPSQLSGGEMQRVSIARALAKKPKLLLC
                     DEPTGALDSKTGQHIMQLLQEASKDEDVAVVLVTHNTEFKAFGDTIIYLKDGKISSID
                     HKQSV"
     gene            1102..3375
                     /locus_tag="TVB59_001845"
     CDS             1102..3375
                     /locus_tag="TVB59_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1010699.1"
                     /translation="MKYLNLKLRRDLKHHWQQFFSVFLMSLLSVLIFVGLQGAWHGLE
                     KSLDNYISTSHLPTVWVQATNLTKQDIEKIEALNQVSKVRPKIRVTAAIDSDSDLEHY
                     LTLDSLQSTSDQVTRVVAGEAFSTKETDKVWLNKEYADANHLSLGDKISLTLSGQSIS
                     VTLAGLVQSADRIYFTGSLEYIAPNYDNYAYGYISKKSLAKLLQTQLPDNMVDIYASS
                     DDLRDDIENILGNKLVSYYNQTTLTDVSEAVDRVGQIRNLSYLFSFIFILLAILSMFT
                     TIRRLIESQTKEIAIIKALGYSNIQVSGHYISFGLLVGTLGALSGLLVSPAMSWFVLE
                     TQKRMFSLPKWEIAYSLSSLVVALLVVMICVTSAYFASRKAIKGLPAVFLRGKNRDVK
                     HILLEKIKPLWRSISDEAKWAIRDALTHRIRILMGIIGVAGSMMLLIAGIGMPISMNH
                     LVDKAYNKDFSYSKRLTVSDYESANKAYKGQWVQINQAHFSKDDGYNRLLIIISKGSL
                     VNATTEDGDKIKEGGLYVTNSFAKLANIKVGDKLSVTPYQDKHQYTFSVKGILTSETN
                     QGAYIMADTFKKAGGAFHPHTLLVDKQVSASTIAQDQNVLTVIDKSSQESNAYDLVNS
                     LMSVFLMIIGFALLLVIVVLYNLGSLNFVERTRDYATLQVLGFSKRNLQNITMLENLM
                     TTSVGWLLGIPMGIWFLEQYVATFSTIRLEYTAYVTWQVLLAASVLVWLTSLMTTLFI
                     SRKIRTIDMVDALKGVD"
     gene            3849..5870
                     /locus_tag="TVB59_001846"
     CDS             3849..5870
                     /locus_tag="TVB59_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL1010700.1"
                     /translation="MITKKQRKLKRHTTIRRLCHQALAATLITGSLMGTGLLGNKVVY
                     GDMKSDAKKVLATLQKGNHKQELKKVLRTIGDDSLLLLWLLVSGDSNLDESNKSFDYL
                     SIWNTGSRVGKVISPTEYFKQESKNTENRQAVYSEFKQRVEERSKKAKEATEALNQKA
                     QLEATVKNINEELEKTREGFKVVSENSNKLEKQLMAEKIKTRTAEETAKQAKTDKEKA
                     EAEAKKAKEEAKTAEGKVKQAETEKRNAEAKARTAEEEAKQATADKEKAETEAKKAKE
                     EAKTAKEAAHQEQEKAKQLEQANQQANQRANLAEKSKKDLETQKEKLEQEIKEATEAK
                     NKAEQKLKDLQDSASQGSELSKQLLKEKEELTTKLQELQKQAEEKTTEIEKLKQELEA
                     NKQNSGQLGQQEQKLQEQLNKVQKELKQKEMELKQAQEQLKQEQKPHEGGGDSDASKA
                     RITELEKQVQTLTKEKADLSSTLESTKAQLSETQARLSEAQKQLTAAQEKLTTLEAEK
                     TALQHQVETISKQLSETRDLSEKEKAALQEQINKLKAEIEQKTKEIEALKQGMQSHQG
                     QEKPKDPKTPETPKDPKTPEKNDQPQAPEKRSVPWTALTPAKPIDTTKAPKSSAPSPQ
                     TGAATPKKQLPATGDTATPSFFTAAAMAVLASVGVLNLSPRRKKNQNNR"
     gene            6287..7129
                     /locus_tag="TVB59_001847"
     CDS             6287..7129
                     /locus_tag="TVB59_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEL1010701.1"
                     /translation="MVSVLSRVIKGIIIALGFILPGVSGGVLAAILGIYERIIAFLAH
                     IREHFVENVLFFLPVGVGGILGIALFSYPVDYLLKHYQVPVLWGFAGAIIGTVPSLIK
                     TSTKTSQRDQVDWLWLVLTFVLSGLGLYFLNDLVGTIPASFTAFVLAGALIALGILVP
                     GLSPSNLLLILGLYSPMLIGFKSLDLVGTFLPIAIGGLLTMLAFSKIMDFALKHYHSR
                     VYHFIIGIVLSSTLLILIPNSSNKEAISYAGAGLGTWLMALLLFGLGVWLGLWMSQLE
                     EKYK"
     gene            complement(7232..>7716)
                     /locus_tag="TVB59_001848"
     CDS             complement(7232..>7716)
                     /locus_tag="TVB59_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HEL1010702.1"
                     /translation="FKPGEVSFPSGRVEEGETYQQAAIRETVEELNIEPEQVHVWGEI
                     DYLVQPTRSIHCFVAELAIDDWRRLRVNEEVDSLFTVPLEELMAQAPVAYPLQMQSII
                     SSDFPLDRIPNGEQYRLRYMQDQVLLYEHLEKPIWGITAQLTNRFIEIVTEARQHDDI
                     "
BASE COUNT         2552 a         1595 c         1541 g         2028 t
ORIGIN      
        1 ggaagaggct tttataaaaa atacatgaat gcctatgggc aggtggcaag gctgcattct
       61 cagcaatggt acaccgatgt cgttcatctt cctgttgaat ttcctatgtc agccgatggg
      121 cataggccag tctctgagag gtaccggaca ctatcagaca aagaaatcag agaaggcttt
      181 ctctccattg gaaaaacacc ggagcttgtc agtggcagtc aggtcgagag attgcgaaaa
      241 atcattaacc tatatgacct gccggttgtc gttccaattg acgaggcagt cactcaagca
      301 gaggagcaaa tcagaaccaa cagagaagct gtctccaagc ggattattga gcagtataaa
      361 gagccttcat taaaagaaaa aataaaattt atatcagaat tttaggagtg tagatgattt
      421 catttaagaa tattagcaag acataccaag tcggagacca agaggttaaa gtattagacg
      481 atgtttcctt tacgattgaa aagggaaggt ttactgttat tttaggcccc tctggttcag
      541 gaaagagcac gctcttaaat ttacttggag gaatggaccg ggcaagcaag ggaaccttta
      601 tctttgaggg taaggacatt acagccttaa atgataaagc attatctgat tatcgcaaag
      661 aggttgtagg ctttgtcttt cagttttaca atcttattcc aagcctaaca gccttagaaa
      721 atatcagtat cgccgcacag ctaaccggaa acacagcaca atcagaggta ttgttggata
      781 aggtggggtt atctcatcgg aaaaacaatt tccctagcca gctgtcaggc ggagaaatgc
      841 agcgcgtatc catagccaga gctctggcaa agaagccaaa attattgcta tgtgatgagc
      901 ctaccggtgc ccttgattcc aaaacagggc agcacattat gcagctactt caggaagcgt
      961 caaaggacga ggacgtagcg gttgtcttgg tgacacataa cactgaattt aaagcttttg
     1021 gcgataccat tatttaccta aaggacggaa agataagctc gattgatcat aaacaatcag
     1081 tttagaggat tggagctaaa catgaaatat cttaatttaa agctaaggcg agatttaaag
     1141 catcattggc agcaattctt ttcagtgttc ttgatgtcct tattaagtgt tttaatcttt
     1201 gttggtctac agggtgcttg gcatgggctg gaaaaaagct tagacaacta tatatctacc
     1261 tctcatttgc caaccgtttg ggtacaggct actaatctaa caaaacagga cattgaaaaa
     1321 atagaggcct taaatcaagt cagcaaggtt agacctaaga ttagggtcac tgctgctatt
     1381 gattctgaca gcgacctaga gcattactta acgctagatt cattacagtc tacctcagat
     1441 caggtgacac gtgttgtagc tggcgaggcc ttttcaacca aagaaaccga taaagtatgg
     1501 ttgaacaagg aatatgctga cgctaaccac ctatccctcg gtgataagat cagcttaaca
     1561 ctatcaggtc aatcaattag tgtgactctt gcgggtcttg tccagtcagc agacaggatc
     1621 tactttacag gcagcttaga gtatatagct cctaattatg ataactatgc ctacggctac
     1681 atctcaaaaa agagcttagc taagctcctt cagacgcagc tgcctgataa tatggttgac
     1741 atttacgcct cgtctgacga tcttcgagac gacatagaga acattttagg caataagctt
     1801 gtttcttatt acaatcaaac aaccctaact gacgtctctg aggcagttga tagagtagga
     1861 cagattagga atctctctta tttgttctcc tttatcttca tcttactagc tattctatcc
     1921 atgtttacca cgatcagacg tctcatcgaa agtcaaacaa aggaaattgc tatcatcaag
     1981 gccttaggct attctaacat acaggtcagt ggccactaca tttcctttgg cttgttggtt
     2041 ggaacattag gtgctctttc tggtcttctg gtatctcctg ctatgtcctg gtttgtccta
     2101 gagacccaaa agagaatgtt ctcacttcct aagtgggaaa ttgcttactc tctgtcttcc
     2161 ctagtagttg cattactggt ggttatgatt tgtgtgacat ctgcttactt tgcttctcga
     2221 aaagccatta aagggctgcc agcagtattc ttacgaggaa aaaacaggga cgtcaagcat
     2281 attttgctcg aaaaaatcaa gcccttatgg cgtagtattt ctgacgaagc taagtgggct
     2341 atacgtgatg ctttgacaca ccgcatcaga attttaatgg ggattatagg ggtagctggt
     2401 agtatgatgc ttttaattgc cggtattggc atgcctatct ctatgaatca ccttgttgat
     2461 aaggcctata acaaggactt tagctactcc aaacgcttga cggtttctga ctacgaatcg
     2521 gccaataagg cctataaagg ccaatgggtg caaatcaatc aagcccactt ctcaaaagat
     2581 gacggctaca atcgtctctt gattattatc agcaagggaa gccttgttaa cgccaccaca
     2641 gaagatggtg acaagataaa agagggtggt ctctatgtta ccaacagctt tgccaagcta
     2701 gccaatatca aggttggaga caagctatct gtcacaccct accaggataa gcatcagtat
     2761 acctttagtg ttaagggaat tctgaccagc gaaactaatc aaggtgccta tatcatggct
     2821 gataccttca aaaaagcagg cggagctttt cacccacaca cattgttagt agataagcaa
     2881 gtttctgctt ctacaatcgc tcaggatcag aatgttttaa ccgtcattga taagtccagc
     2941 caagaaagca atgcctatga ccttgtcaat agtctaatga gtgtcttttt gatgatcatt
     3001 ggctttgcct tgctgctagt catcgttgtg ctgtataatt taggctcttt aaattttgta
     3061 gagcgcacaa gagactacgc aacccttcag gttctaggat tttcaaaaag aaatctccaa
     3121 aacataacaa tgctcgaaaa tctcatgaca acctctgtgg gctggctctt gggaattcct
     3181 atggggattt ggtttttaga gcagtatgtc gccaccttct ctacgatacg tcttgaatat
     3241 acggcttatg tcacttggca ggttctgcta gcggcaagtg tccttgtctg gctaacatca
     3301 ttaatgacca ctcttttcat cagtagaaag attagaacaa ttgacatggt tgatgcctta
     3361 aagggagtcg actaacctca ctttatcaca tacctgactc tctctctttt atggttaagc
     3421 atcatcactg cactggttct gatatgatga ctgataaagc tgtaattgtg ctgtaacaag
     3481 cactgtcatt acatagcaac acccttaaaa acaagcatca gatttggtgc ttgtttttga
     3541 atttattgct aatgctaaac gcaacgatta tcacaaatca tgcagtacac gcttataaca
     3601 gcttaagcat gcccattatt caaaaaacgt tgatcaaaat gacttccctg aagtttagat
     3661 cattcctcaa tttattgata caaatgtgat aaagtcatac gatcttcttg tttattaaaa
     3721 aaaaaaaaaa cgaaactacg gagagaaaga tgagctttgt cgtttctcac ttccaaccgc
     3781 catgttaaaa tcttctctga gaaagaatgt tataaaaaat aatcattcta tcaccaaagg
     3841 agagaaaaat gataactaaa aaacagagaa aactaaaaag acacacaaca atcagacgcc
     3901 tgtgtcatca agccctagca gctaccctca tcacaggaag cctgatggga acaggactac
     3961 ttggaaataa agtcgtgtat ggggatatga aaagcgatgc caaaaaggta ttagcaacat
     4021 tgcaaaaagg taatcataaa caagagttaa aaaaagttct tagaactatt ggtgatgata
     4081 gtttgctatt attatggtta cttgtatcgg gtgattccaa tttagatgaa agtaataaaa
     4141 gttttgatta tttatcaatt tggaatactg gatctagagt tggtaaagtg atatctccta
     4201 ctgaatactt taaacaagaa tcaaaaaaca ctgaaaatag gcaagctgtt tatagtgaat
     4261 ttaaacaacg cgtagaagaa cgatctaaaa aagccaagga agccactgaa gcactaaacc
     4321 aaaaagctca attggaggct acagttaaaa atataaacga agaacttgaa aaaactagag
     4381 aaggttttaa agttgtgagt gaaaactcaa acaaattaga aaaacaatta atggctgaga
     4441 aaataaaaac acgtacagct gaagaaactg ccaaacaagc taaaaccgat aaagaaaaag
     4501 cagaggctga agctaaaaaa gcgaaagagg aagctaagac tgcggaagga aaagttaaac
     4561 aagcagaaac tgagaaaagg aatgcggaag ctaaggctag aaccgctgaa gaagaagcta
     4621 aacaagctac ggctgataaa gaaaaggcag agactgaagc taaaaaagcg aaagaagaag
     4681 ctaagaccgc taaagaagct gctcatcaag aacaagaaaa agctaaacaa ttagaacaag
     4741 ctaatcaaca ggctaaccaa agagctaatc tggcagaaaa atctaaaaaa gatttagaaa
     4801 ctcaaaaaga aaaacttgaa caagagatta aagaagctac agaagctaaa aacaaagccg
     4861 agcaaaaatt aaaagaccta caagattcag ctagtcaagg cagtgaattg tctaaacagc
     4921 tgttaaaaga aaaagaagaa ttaacaacaa aacttcaaga gcttcaaaaa caagctgagg
     4981 aaaaaacaac tgaaattgaa aagctaaaac aagagcttga agctaataaa caaaacagtg
     5041 gtcagctagg tcaacaggaa caaaagcttc aagagcaatt gaataaggtt caaaaagagc
     5101 tgaaacaaaa ggaaatggag ttaaaacaag ctcaagaaca gctgaaacaa gaacaaaaac
     5161 ctcacgaagg tggcggagat tctgacgctt ccaaagcaag aatcactgag ctagaaaaac
     5221 aagttcaaac actaaccaag gaaaaggcag atctgtcatc aacccttgag tcaacaaaag
     5281 ctcaattgtc agagactcaa gcaagactat cagaagctca aaaacaattg actgctgctc
     5341 aagaaaagtt aacaacactt gaagccgaga aaacagcgct tcaacatcaa gttgagacca
     5401 tttcaaaaca gctatcagaa acacgtgacc ttagcgaaaa ggaaaaagca gcactccaag
     5461 agcaaatcaa taagctaaag gctgagattg agcaaaagac caaggaaatt gaagccttaa
     5521 agcaaggcat gcaatcacat caaggtcaag aaaaaccaaa ggatccaaaa actccggaaa
     5581 caccaaagga tccaaagact cctgagaaaa acgatcagcc acaagcgcct gaaaaacgta
     5641 gtgtcccttg gactgctctt acaccagcta agccaattga cactaccaaa gctcctaaga
     5701 gctcagcacc aagcccacag actggggcag caacacctaa aaaacaatta ccagcaactg
     5761 gtgatacagc gacacctagc ttctttaccg ctgctgctat ggcagtattg gctagcgtcg
     5821 gtgtcctaaa tctctcacct agacgcaaaa agaatcaaaa caaccgttaa tgtagagact
     5881 ctcatatctg gattgaataa cagcaaaccc gacatgagca aaaacaaatg tctaaccaaa
     5941 aatcactgac attagtactt taaccaaagc ctttgagtca agctaaacag gctgtcctgc
     6001 ctattggctt gactcgtttt gtgattgtga aacacaccaa ggtcaaacct accttgtcct
     6061 ccattttaaa cctactcttt tctcccatac ccactttagc ttacgcaaga aggtgcctaa
     6121 tcatcacttt tggtagcttc gatgctctat ataaatggat caacaaagat aaatcataca
     6181 aaactgcgag ttgttcctat agtcacgata gctcttacag atatgaaaag taaatacagc
     6241 tattaaaaat atggtacaat aggggtacga tttttaggag gcatgtatgg tttcagttct
     6301 ttcacgagtg attaagggaa taattattgc gcttggcttt attttaccgg gagtatctgg
     6361 aggagtatta gccgctatcc ttgggatcta tgagcgtatc attgcctttt tagctcatat
     6421 acgtgagcat tttgttgaga atgttctctt tttcctgcct gttggggttg gtggtatttt
     6481 agggattgcc ctcttttctt accctgttga ctatctgctc aagcactatc aggtaccagt
     6541 cttatggggc ttcgctgggg ccatcatagg aaccgtacct agcctgataa agacttcgac
     6601 aaaaacatct cagcgtgacc aagttgattg gctctggcta gtattaacct ttgtcctatc
     6661 aggactggga ctttatttct taaatgatct cgttgggaca atacctgcaa gctttaccgc
     6721 ctttgtccta gctggtgcct tgattgcttt aggtattttg gtacctggtc ttagcccgtc
     6781 taatctttta ttaattttag gactttactc acccatgctg attggcttta aatcacttga
     6841 tttggtagga acctttttac ccattgctat tggtggctta ttaaccatgc tagctttttc
     6901 caagattatg gattttgctc tcaagcacta ccattcacgc gtttaccact ttattatcgg
     6961 tatcgtccta tccagcaccc tgcttatttt aattccaaat agcagtaata aggaagctat
     7021 ctcttacgcc ggtgcaggtc ttggcacctg gctaatggct ctgctattat ttggccttgg
     7081 tgtctggctt ggtctatgga tgagccagct tgaggagaaa tacaaataac actcgataca
     7141 ccagcaagta cctctaacag cagcattaag atcaaaaaaa cgaatgacta gctctcagcc
     7201 ttatcaccag ctgtgactag cattcgtttt tttatatgtc atcatgctgt cttgcctctg
     7261 tcacgatttc tataaaacgg ttcgtcaatt gagcagttat accccagata ggcttttcta
     7321 aatgctcata gagtaatacc tgatcttgca tgtacctcaa cctgtactgc tctccattag
     7381 ggatacgatc caacggaaag tctgacgaga ttatcgattg catttgtaaa ggataagcaa
     7441 caggagcttg cgccatgagc tcctccaaag gcaccgtaaa caagctatca acctcttcat
     7501 tgaccctaag ccttctccaa tcatcaatag ccagttccgc aacaaagcaa tgaatgctac
     7561 gagtcggctg aactaaatag tcaatctccc cccaaacatg aacctgctca ggctctatat
     7621 tgagctcctc taccgtctca cgaatagccg cctgctgata agtctcaccc tcctccacgc
     7681 gcccactagg aaaagaaacc tcccctggct tgaatg
//
LOCUS       DARYNN010000075         7672 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.075, whole genome shotgun sequence.
ACCESSION   DARYNN010000075 DARYNN010000000
VERSION     DARYNN010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7672
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.075"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(171..461)
                     /locus_tag="TVB59_001849"
     CDS             complement(171..461)
                     /locus_tag="TVB59_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010703.1"
                     /translation="MLIPITEYYIEEEYAYALRLMRQMLERQRIATVARLANSQGEAI
                     KKTFKDQIKATASQTKESLQIMEGQLDTAIKGAVRDQLEQVVKKKLPKYNKL"
     gene            complement(442..834)
                     /locus_tag="TVB59_001850"
     CDS             complement(442..834)
                     /locus_tag="TVB59_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010704.1"
                     /translation="MADRIVEEVAIYRKLREMDDAEQDFLRQKKGYQKREDSLSERRH
                     VLDDLINSEYQKMSVFLKRLDLSANAASDFFKELDRLKDQSNAEFHLQRAALEEERAQ
                     STKTFRQEQDQRETELLDMRRAYANTNN"
     gene            complement(816..2105)
                     /locus_tag="TVB59_001851"
     CDS             complement(816..2105)
                     /locus_tag="TVB59_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010705.1"
                     /translation="MMISDSSYKKLSEQVYNVEPSKAKSNDAPIVLKGNRLIDDKTGK
                     QYRVLLVQDNNNDAHKINDNGMQAMAVAPIVQGDVDTSQVVIAYAGTNAADSRDLDTD
                     WQLLIRGNQDDLVSGNLDGGNFVIAENQLRSAQKFYQQVKRKYPHSALTTTGHSLGAY
                     LALIVAAEHKIPATTFNGPDPVRGMSAEAITWVKANSNMYNNFRINFDGIGNFGAYFG
                     TDDLAISRNVDAMLLSANPLYYHDLGAYRFNQKGQIVDRDGKLIGTQYLVSRAYLTVL
                     ASKKRMSSYNQLKKHWQSTGKGISSSEELFLDAAQGMILGSSMAKVAREGADEALDHK
                     TVADAKLMEVWSAIDFNAFHELPYYEVQALFASYGITYDRFVRDFQDYTQSKVSKLSA
                     LATDFENLNRDIQTVIDSKLETDQQLAGEFRAWQTEL"
     gene            complement(2107..2538)
                     /locus_tag="TVB59_001852"
     CDS             complement(2107..2538)
                     /locus_tag="TVB59_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010706.1"
                     /translation="MKKSTKAFIALMILIGGLLMVFSLNGKRTEEQQKKDLETSIAKL
                     LVHDYEDVKEVKFTGWGRSRETGSWGTIVVINGENEIGFSFDGLSGLADISGRSYHPD
                     TFKLVEKNSLEEMGPVKYRIKDIEKVSLEGVSITYSREKRS"
     gene            complement(2759..3193)
                     /locus_tag="TVB59_001853"
     CDS             complement(2759..3193)
                     /locus_tag="TVB59_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010707.1"
                     /translation="MKKSTKAFIALMILIGGLLMVFSLNGKITEEQQKKDLETSIAKL
                     LVHDYEGVKTIKFQGWGHSRETGSWGTTVIINESNQMSFSFSSIKTLEDIGSTRYNPN
                     TFKLVEKPETDSKPRIMDRMNEINATSLAGVTVIYSNNNQED"
     gene            3532..3618
                     /locus_tag="TVB59_001854"
     CDS             3532..3618
                     /locus_tag="TVB59_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014868551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL1010708.1"
                     /translation="MQLMLGFGSFLLSLIGLVVIIVKMSNKK"
     gene            complement(3966..6407)
                     /locus_tag="TVB59_001855"
     CDS             complement(3966..6407)
                     /locus_tag="TVB59_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEL1010709.1"
                     /translation="MMIYSLKMQDIFNQAQFQAERFDSPYLETWHILLAMVAVDHSLA
                     AMVLSEFERKIRAEEYEAAAILAMGKSPKEVTSVQFKPQSKALSEILAFAHAICQVIN
                     EHEVGSEHVLFAILLNPDIMASRLLELAGYRLKDSGKGEPRFADLRKAIELNAGYSKE
                     TIKAIHELRKPKKSKSVGTFSEMMKPQSTAGELSDFTRDLTEMARQGLLEPVIGREKE
                     VSRMVQVLCRKTKNNPVLVGDAGVGKTALAYGLAQRIANGAIPYELQDMRVLELDMMS
                     VVAGTRFRGDFEERMNQLIDDIEADGKIILFVDELHTIMGSGSGIDSTLDAANILKPA
                     LSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPSVEDAYQILLGLKPSYEQY
                     HNVTISDTAVHTAVKLARRYLTSKQLPDSAIDLLDEASAMVQSMVKKTQPDFITPLDQ
                     ALLDGDMSKVSALLVKEDKQPKLKPTAVTEDDMLHTLSKLSGIPLEKLTQADSKKYLN
                     LEKELHKRVVGQEMAVSAIARAIRRNQSGIRTGRRPIGSFMFLGPTGVGKTELAKALA
                     ELLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYAVLLFD
                     EVEKAHPDIFNILLQVLDDGMLTDSRGCKVDFSNTIIIMTSNLGATALRDDKTVGFGA
                     KAIGHDHQAMEKRILEELKKAYRPEFINRIDEKVVFHSLTQENMRDVVKIMVKPLIAA
                     LAEKHISLKFQPSALKYLSEAGYDVEMGARPLRRTLQTEVEDRLAELMLSGELSSGQS
                     LKIGVSRGKLAFDIA"
     gene            complement(6407..6868)
                     /locus_tag="TVB59_001856"
     CDS             complement(6407..6868)
                     /locus_tag="TVB59_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEL1010710.1"
                     /translation="MPTKNTSDSIEEYIKELLAQSGIAEIKRSMLADSFQVVPSQINY
                     VIKTRFTESRGYEVESKRGGGGYIRIAKVHFSDKHHLIGTLIASIDDCLSEQAFTDSI
                     QLLFDEQLLTEREGNIILAVASNDVLGHQAPEIRARMLYRLLQRIDRKGSN"
     gene            complement(7038..7241)
                     /locus_tag="TVB59_001857"
     CDS             complement(7038..7241)
                     /locus_tag="TVB59_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HEL1010711.1"
                     /translation="MAQGTVKWFNAEKGFGFISTENGQDVFAHFSAIQSDGFRSLDEG
                     QRVTFDVEDGQRGPQAVNITKLS"
BASE COUNT         2173 a         1801 c         1348 g         2350 t
ORIGIN      
        1 tcagtacact ggtcctctct cgtctttagc tatcggtcac tctgtataca attatcccct
       61 tttaaaaata acaggacaaa agctctggag gctgatcgcc ttttttgatc atacttgctt
      121 ggtaggtatt gattgaaccc ctacggtctc ttataaatga caccatttga ctatagcttg
      181 ttgtattttg gcagcttctt ctttacgacc tgctccagct gatctctgac cgctcctttt
      241 atggccgtat ctagctgccc ttccatgatc tgaaggcttt ccttagtttg gctggcagtc
      301 gctttgatct ggtctttaaa cgtttttttg atcgcttcac cttggctgtt cgcaagccta
      361 gccactgtgg caatcctttg acgctccagc atttgacgca ttagcctcag ggcataggcg
      421 tattcttctt cgatataata ctcagttatt ggtattagca taagctctcc tcatatctaa
      481 taactctgtc tctctttgat cctgctcttg acgaaaagtc ttggttgact gtgctcgctc
      541 ctcttcaaga gctgcccgct ggaggtgaaa ctctgcgttg gattgatcct ttaagcgatc
      601 tagttccttg aaaaaatctg acgcagcatt ggcagatagg tctaaacgct tcaaaaaaac
      661 actcatcttc tggtactcag agttgatcaa atcatctaag acatgtcttc tttcggataa
      721 gctgtcttca cgcttctgat agcctttttt ctggcgcaga aagtcctgct cggcatcatc
      781 catctcccgc agcttacgat agatagccac ttcctctaca attctgtctg ccatgctcta
      841 aactctcctg ctaactgttg atccgtttca agcttgctat caataactgt ctgaatatct
      901 ctattcaggt tttcaaagtc tgtggccaag gctgacagct tgctgacctt ggattgagta
      961 tagtcctgaa agtctcggac gaagcggtca taagtgatcc cataagaagc aaacaaggct
     1021 tgcacctcat aatagggcag ctcatgaaaa gcgttaaaat caatcgccga ccacacttcc
     1081 ataagctttg cgtcggcaac cgttttatga tccagtgcct catcagcccc ctctcgagca
     1141 accttagcca tggacgagcc taggatcatt ccctgtgccg catctaaaaa gagctcctca
     1201 gaactactga tccccttacc ggtagactgc cagtgttttt tgagctgatt gtagcttgac
     1261 atacgctttt ttgaggcaag gacagttaaa taggcccgac tcacaaggta ttgtgttcca
     1321 atgagcttac cgtctctatc tacaatctga cccttttgat taaaacgata agctcctaaa
     1381 tcgtgataat acaaggggtt ggctgataag agcatagcat cgacattccg agaaatagcc
     1441 aaatcatcag ttccaaaata ggcaccaaaa ttgccaatgc catcaaaatt aatgcggaaa
     1501 ttattgtaca tattgctatt agccttaacc catgtgatag cttcagctga catgccgcga
     1561 acagggtctg gaccattaaa ggttgttgct gggatcttat gttctgcggc gactattagt
     1621 gctagataag ctccgagaga gtgacctgtg gttgttaagg cagaatgagg gtactttctt
     1681 ttgacttgtt gataaaactt ttgagcagat cgtaattggt tttcggcaat aacaaaattg
     1741 ccgccatcaa gattgccgct gactaaatca tcttgattgc cccgaatgag cagctgccaa
     1801 tccgtatcaa gatctctgga atccgcagca tttgtccctg cataggcaat cacaacctgg
     1861 gaggtatcga catcaccttg aacaataggg gctacagcca ttgcttgcat accgttgtca
     1921 ttgattttat gggcatcgtt gttattatcc tgaactaaga ggactcggta ttgcttaccc
     1981 gtcttatcat cgataagacg atttcccttt aaaacaatag gggcatcatt tgacttagct
     2041 ttactaggtt cgacattata gacctgttct gacaacttct tataactact atcggatatc
     2101 atcatattaa ctccttttct cacgagaata cgtaattgac actccctcta aagaaacttt
     2161 ttcaatgtct ttaattctat atttcacagg ccccatttct tccagactat ttttctcaac
     2221 taacttaaaa gtatctggat gataagagcg cccactaata tccgctaatc ctgacaaacc
     2281 atcaaacgaa aagcctattt cattttctcc atttataact actatcgttc cccacgaacc
     2341 tgtttcccga gaacgtcccc agcctgtaaa cttaacttct ttgacatctt catagtcatg
     2401 aaccagcagt ttagcaatac tagtttctaa atcctttttt tgttgttcct ctgttctttt
     2461 gccattcaaa ctaaaaacca taagcagccc tcctattaga atcattaaag caataaaagc
     2521 tttggtcgac tttttcatga aagttctcct ttcaatttct aataatagta tacaataaaa
     2581 atgagtaaaa aataaagcta aacagttttt ctataatgtt atctgttata agttaaattc
     2641 tcctgctaat aatctttcca ttaaaacaat agggacatca ttaaatttag ctttccttag
     2701 ttcgatatta taggtctgtc ttgctaactc attatagcta ctatcggata tcgccatatt
     2761 aatcctcctg attgttattt gaatagataa cagtaacacc tgcaagagag gtcgcattaa
     2821 tctcgttcat cctatccata attcttggtt tagaatcagt ttcaggtttt tctaccaatt
     2881 taaaagtatt gggattatat cttgtgcttc ctatatcttc taaagttttt atactagaaa
     2941 aagaaaaact catttgatta ctctcattaa taatcaccgt cgttccccac gaacccgttt
     3001 cacgagaatg tccccatcct tgaaatttaa tggttttaac cccttcatag tcatgaacaa
     3061 gcagcttagc aatgctggtt tccaaatcct ttttttgttg ttcttctgtg attttaccat
     3121 tcaaactaaa taccataagc aaccctccta tgagaatcat taaagcaata aaagctttgg
     3181 tcgacttttt catgaaagtt ctcctttcaa tttctaataa tagtatacaa taaatcagaa
     3241 gtcatagaat aaccatattc aatttttatg tcgtattcga taaaaaatat accatctcaa
     3301 caaacaatcg cttaaaaacg attttagggt atatttcttc cctgcaagca aaggacacaa
     3361 aaaagccatc tgaattttca acatcagaca gctatttcgt atgactatgg tataatggtt
     3421 tctgcagaaa agttaaggcg gtggctctaa tttctgaaag gtggtggtgc ttatgactgt
     3481 aagtgctaaa atccaaagag aaaggagcga atattgtccg tttacgaggc aatgcaactc
     3541 atgcttgggt tcggtagttt tctactttca ctcattggct tagttgttat tatcgtaaaa
     3601 atgagcaata aaaaataacc gtctaacttt agcgagtaac ggttattttt taactaaaaa
     3661 caagctaccg tcttaaacgg ttctgcattg ggtagttgtt ttgagcaact gtcctttttc
     3721 tattttcatt atatctcagc taagaaaaat agtcaaatga gatactattt tggcagctaa
     3781 attggtagct aaatcttcaa aatacctatt tttcgctaaa ttcgattaaa attaaatcct
     3841 atctgtctgc tacgctttaa actctcactc tagtacttca tcaccatacg acaaaaagag
     3901 cctgagaaac tttttgtctc agactctctc aaagctctta gcttaatatc aagcaaagtc
     3961 atgcattaag cgatatcaaa agctagtttt ccacgtgata caccaatctt gaggctttga
     4021 ccgcttgata actctcctga cagcattaat tctgctaacc tgtcctcaac ctctgtttgc
     4081 aaggtgcgac gaagtgggcg agcgcccatt tcaacatcgt aaccagcttc agacaagtac
     4141 ttgagagctg atggctggaa cttaaggcta atatgctttt ctgccaaggc tgcaatcagc
     4201 ggcttaacca taattttcac cacatcacgc atgttttcct gtgttaggct atggaagacc
     4261 accttttcat caattctgtt gataaattca ggccgataag cctttttcaa ttcctctaaa
     4321 atacgctttt ccattgcttg atggtcatga ccgatcgctt tagcgccaaa tccaaccgtc
     4381 ttatcatctc ttagagcagt tgctcctagg ttgctcgtca tgataataat cgtgtttgaa
     4441 aaatcaacct tacatccacg actatctgtt aacataccat catcaaggac ctgcagcagg
     4501 atattaaaga tgtctgggtg agccttttca acctcatcaa aaagaagaac ggcataaggc
     4561 ttatttctaa ccttttcggt tagctctcct ccctcatcat agccaacata gccaggagga
     4621 gccccattaa gacgggaggc tgcaaatttt tccatgtact cagacatatc aaaacgaata
     4681 agggctgact catcatcaaa gagtaattcg gccaaggcct ttgctagctc tgtttttccg
     4741 acaccagttg gaccaagaaa cataaaggag ccaatcggac gcctgcctgt gcgaatgcct
     4801 gactggttac gacgaatggc tcgtgcaata gcagaaacag ccatttcctg accaacaaca
     4861 cgcttatgca attccttttc cagattcagg tattttttac tatccgcctg agttagtttt
     4921 tctaggggaa tacctgatag cttgcttaag gtgtgtaaca tatcatcttc agtaactgct
     4981 gttggtttta gctttggttg cttatcctct ttgactaaaa gggctgacac cttgctcata
     5041 tcaccatcaa gcagggcttg atcaagcggt gttataaagt caggctgcgt ctttttaacc
     5101 atactttgca ccatcgcact ggcttcatca agcagatcaa tcgctgagtc tggaagctgc
     5161 ttacttgtca aatagcgccg agccagcttc acagcagtat ggacagctgt atcagagatt
     5221 gttacattat ggtactgttc ataggaaggc ttcaagccaa gcaaaatctg ataagcgtcc
     5281 tcaacactag gctcctcaat caatatcttg gcaaagcgac gagaaagggc tgcgtccttt
     5341 tcaatgtgct tttgatattc ctcttgagtt gtagcgccaa ccatatgcag ggtaccgcga
     5401 gaaagggctg gctttagaat attagcggca tcaagtgtgc tgtcaatacc acttcctgat
     5461 cccataatgg tatgtagctc atcgacaaac aaaatgatct taccatctgc ttcaatatcg
     5521 tcaatgagtt gattcatgcg ctcttcaaaa tccccacgaa aacgggtacc tgcaaccaca
     5581 ctcatcatgt caagctccaa gacacgcatg tcttgtaatt cataaggaat ggctccatta
     5641 gcaattcgct gcgctaagcc ataagctaga gcagtttttc cgacacccgc atcaccaaca
     5701 agaacaggat tatttttcgt cttacgacaa agcacctgaa ccatacgtga cacctctttt
     5761 tctcgtccga tgactggctc taataagccc tgtcttgcca tctctgtcag gtctcttgta
     5821 aagtctgata gctcaccagc tgtactctgt ggcttcatca tttcagaaaa ggtgcctact
     5881 gatttactct ttttaggctt acgcaactca tgaatcgcct taatagtttc cttgctatag
     5941 ccggcattta gctcaatagc cttacgtaaa tccgcaaacc taggctctcc cttgccagaa
     6001 tccttgagcc tgtagcctgc caattctaac agacgactgg ccataatatc cggattgagc
     6061 aaaatagcaa agagtacatg ctctgagcca acctcatgct cattgataac ctgacagata
     6121 gcatgagcaa atgctagtat ttctgataag gccttggatt gtggcttgaa ttggacagaa
     6181 gtcacctctt tgggactttt tcccatggct aaaatagcag cagcctcata ctcttcagcc
     6241 ctaatctttc gttcaaattc gcttaacacc atggccgcta aggaatggtc aacagctacc
     6301 atagctaata aaatatgcca ggtctcaagg taaggactat caaagcgctc tgcttgaaat
     6361 tgagcctgat taaaaatgtc ttgcatcttt aatgaataaa tcatcactaa ttgcttccct
     6421 ttctatcaat tcgttgcaat aggcgataaa gcatacgagc acgaatttct ggtgcttgat
     6481 gtcccaaaac atcattagaa gctacagcta agataatgtt tccttcgcgc tctgttaaca
     6541 gttgctcatc aaaaagcagc tgaatcgaat ctgtaaaggc ctgctcgctt aaacaatcat
     6601 caatagaagc gatcaacgta ccaatcaggt ggtgcttatc cgaaaaatga accttagcaa
     6661 tacgaatgta gccaccacca ccacgcttac tttctacctc atagcctctg ctttctgtaa
     6721 aacgggtctt gatcacataa ttaatctggc ttggtactac ttgaaaggaa tccgccagca
     6781 tggagcgctt gatctctgcg attcctgatt gggctaacaa ttctttgata tattcttcga
     6841 tactatcgga agtatttttt gttggcatgc cgtcactcct ttgctaaaac gattcatttg
     6901 ctgctttaag cctttatttg actaaaactg actaacatta tatcaaatag cagtcactaa
     6961 aagcaaatgg aaatcactag aatgtaaaag gacaggtgct atcaacaaca cccatcccct
     7021 attatctgct cactagatta agacaattta gtgatattta ctgcctgagg accgcgctgt
     7081 ccgtcttcaa catcaaacgt caccctttgt ccctcgtcta acgatctaaa gccgtcagac
     7141 tggattgctg aaaaatgtgc aaaaacatct tgaccatttt cagttgaaat aaagccaaag
     7201 cccttttcag cattaaacca cttgactgta ccttgtgcca tagtcatcca cttcctttct
     7261 ataacgcatt tgtaaacata gagagaaata aagatgccaa aacacaacta ctaattcaaa
     7321 aactaattta ctcgctcagt gtaacacgaa tggcagccac tgtcaacaca tacccctcac
     7381 aatgacagct tttctactcc acctgctaaa atgtaaaaaa gcaaagtcat gctgaccttg
     7441 ctttaacaat ctaaggcggt agacggattt tagatgcatt gatatcagtg ctttagagta
     7501 actttgaccg acttttgacc gaccgccaat ctaactccct cagcacattt tctacttttt
     7561 cctcggtcac cacttcccaa ggctgcactt tctcccctgg caacacataa tcaaatatct
     7621 gtccgttttt acgcacaatc gctactgtgt ctcctgttat atatccgtca tc
//
LOCUS       DARYNN010000076         7560 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.076, whole genome shotgun sequence.
ACCESSION   DARYNN010000076 DARYNN010000000
VERSION     DARYNN010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7560)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7560)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7560
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.076"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            63..779
                     /locus_tag="TVB59_001858"
     CDS             63..779
                     /locus_tag="TVB59_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1010712.1"
                     /translation="MLKIALCDDNKAFATAVEDLLYQYNQLVPVELDIYEDPCQLIQS
                     LSNDYHIFLLDIEMDNMSGIALAEHIRKDNLSAIIIFLTSHKEYMENIFHVQTFDYLI
                     KPLNEPYFFECLNRALRVLELDKKFFTFSSCHSYYSLSLNDIIYFEKEGRKVLIHTKD
                     KTYSTFLSTKALLKELPEQFIQTHHSYVFNVNYFYKFENNDITLAIDNTRFFIIPISR
                     KFKKGIQENIFSKLRRVNGY"
     gene            769..2061
                     /locus_tag="TVB59_001859"
     CDS             769..2061
                     /locus_tag="TVB59_001859"
                     /inference="COORDINATES: protein motif:HMM:NF025854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEL1010713.1"
                     /translation="MAINAIFHLYTSVVNIVIVNYFFRQKNGQLATFKNIGYLSFLVF
                     IECCTHFFVSGSYASLITLTCSLVTSLIISSSYRYSMKQCIFWSVTLQSIGILLEASL
                     GIILISLKYQISSISGTFLFINLLTISSIIIIFVLKQLFLKTTDNWLDEQTQTNWILK
                     LSIIPMISLSLLLLQLLRLKEEPLFDLFTILLTLGFIIITITSLYLYTYISDQHLQMQ
                     DINLDRVRFQSELKHLENVKENQLSIRALKHDLHNQNIVLLGLLEQKQYTKAQQLLNH
                     NLNLLDGTDTFFTNDTILNYLLNQKAVVAKKNGIVLDIHCLIPTNISLKTEVISVIIG
                     NLLDNSIAATIRNQNKAEKQIQLKVRLFKNQLHIDIENFFDPKELASRSQRKKDGLGI
                     KNVQKIVQQYYGLYQQTIDNNIYKVSIIFSNIVLVSQQ"
     gene            complement(2266..3546)
                     /locus_tag="TVB59_001860"
     CDS             complement(2266..3546)
                     /locus_tag="TVB59_001860"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEL1010714.1"
                     /translation="MKLQKPKGTQDILPVAAAKWQYVEGVARETFKQYHYGEIRTPMF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PVKLYYIGSMFRYERPQAGRLREFHQIGVECFGSANPATDVETIAMAYHLFERLGIKE
                     VTLHLNSLGNAASRAAYRQALIDYLSPMRETLSKDSQRRLDENPLRVLDSKEKEDKIA
                     VANAPSILDYLDEESQAHFDAVRSMLEVLAIPYVIDTNMVRGLDYYNHTIFEFITEVD
                     QSELTICAGGRYDGLVEYFGGPATPGFGFGLGLERLLLILDKQGVELPVEEGLDVYIA
                     VLGAYANVAALALTQAIRRQGFTVERDYLGRKIKAQFKSADAFKAKVVITLGESEIKT
                     GQAVLKHNQTRQEMTVSFDQIQTNFASIFAECIQ"
     gene            complement(3606..4436)
                     /locus_tag="TVB59_001861"
     CDS             complement(3606..4436)
                     /locus_tag="TVB59_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010715.1"
                     /translation="MFGKLLSLLGFVVALTGCGVSQAEKERVVTEYSPIIIKKFQTLG
                     YQGKITVDDYTKMIETGSERLYFTYSEEVDGKVISLKDSISIATYKSPEEDLADAEVD
                     MGIREEAMWQQPAVKAQAAQIKQLFSELETEDLKLISVTGQSVQTISDSDGELIREDV
                     VRGRNELSQDASNNREAGLSIGGYYHIDVSKYLKNHVLEIRIDFDWRMSEEEQDDLSG
                     PRLDFSDRIKSLDFTCLWDGYYKVGFDRVSRSNRSGDIQDMIVLDIRGGKLVRSFSVL
                     "
     gene            4706..4888
                     /gene="rpmF"
                     /locus_tag="TVB59_001862"
     CDS             4706..4888
                     /gene="rpmF"
                     /locus_tag="TVB59_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEL1010716.1"
                     /translation="MAVPARHTSKAKKNKRRTHYKLTAPSVKFDETTGDYSRSHRVSL
                     KGYYKGHKIAKANAAE"
     gene            4904..5053
                     /gene="rpmG"
                     /locus_tag="TVB59_001863"
     CDS             4904..5053
                     /gene="rpmG"
                     /locus_tag="TVB59_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEL1010717.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(5158..5907)
                     /locus_tag="TVB59_001864"
     CDS             complement(5158..5907)
                     /locus_tag="TVB59_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4065 domain-containing protein"
                     /protein_id="HEL1010718.1"
                     /translation="MYQHFILVASSYARGERVGFHLATEGQLDHVAIEEKMQRLSHIN
                     RDDVGVHSFVTDSADWQSVIELDSFFEDIMVCQDFDEFEQVLQSDSKISAIDVAKFFL
                     AMRPLSHLQLQKLVYLAYKTYLLAYGESLFDEKIVAFQYGPVVEEVYHSFKKYGSEVI
                     DIDDHTEYILKDIHLPQALGRMLLVEDAKKIVPVLLDVVKQYGDLTGGELVKLTHSEK
                     GPWQTVFRPQLNCEITDEVILAQGRYERLSS"
     gene            complement(5912..6556)
                     /locus_tag="TVB59_001865"
     CDS             complement(5912..6556)
                     /locus_tag="TVB59_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010719.1"
                     /translation="MPIAAYQYESVVEIISEINRLHYSFSSGLGALLCFNLKKSVSSV
                     VVNNRIDREFQELIVSYKARLNRNISQVSSIRHQFIGIRWRIKQAESISEKLLYYMSE
                     NHEFGRIPLNKCLNDFLGFRILVNNLEVVFAALQNDNRVTNIAKLYLRTDGDYKGIHL
                     YFKNGNNRFFPWELQIWDPEQSRLNELSHKEHKQKRQYISLPQHYFDANLEKEE"
     gene            6961..>7560
                     /locus_tag="TVB59_001866"
     CDS             6961..>7560
                     /locus_tag="TVB59_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL1010720.1"
                     /translation="MKRQSNIRRLCHQALAATLITGSLIGTGLLGNKVVYGDMSADVK
                     KIEQVLQSDSGKLKTVLGQISDPNTLFALFAIISADVNIDPESFSFILNGPITPLLSY
                     FNNPNKNDNRKAVVNEIKKRVSALEQAQKLETKAKIEKQIAESELEKTRNAFKVTIEN
                     LHKLEGLLDTEKQKTRKVEEDYQQAKTDKEKAEADKRNAE"
BASE COUNT         2537 a         1553 c         1195 g         2275 t
ORIGIN      
        1 agcgcttttc atgtcatttt tggtatacta aataccacag tctataggat tatgggggta
       61 ccatgcttaa aattgctctt tgtgatgaca ataaagcttt tgcaacagct gtagaagatc
      121 tattatacca atataatcaa ttagttccag tggagttaga catttacgag gatccttgtc
      181 aattaataca gtcactgtct aatgattacc atatttttct tcttgacatt gaaatggata
      241 acatgtctgg aatagcatta gccgagcata ttaggaaaga taatctctct gctattatta
      301 tctttttaac aagccacaaa gaatacatgg aaaacatttt tcacgtgcaa acctttgatt
      361 acctgattaa gcctttaaat gaaccctatt tttttgagtg cctaaataga gctctaaggg
      421 ttttagagct tgacaaaaaa ttttttacct tttcatcttg ccactcctac tatagcttaa
      481 gcttaaacga tattatctat tttgaaaagg aaggacgaaa agtactcatt cataccaagg
      541 acaagaccta ctctaccttt ttatcaacca aagcattact aaaagagctt cctgaacaat
      601 ttatccaaac ccatcattct tatgtgttta acgtcaatta cttctataaa tttgaaaaca
      661 atgacataac attagctatt gataacacgc gcttttttat cattcctatc agtcggaaat
      721 ttaagaaggg tattcaggag aacatctttt ccaagctaag gagagtaaat ggctattaac
      781 gctatttttc atctttatac atcagttgtt aatattgtga ttgttaatta tttttttcgt
      841 cagaaaaatg gtcagctagc tacctttaaa aacataggtt atctctcttt tttagtattc
      901 atagaatgct gcactcattt ttttgtatca ggaagctatg cctcactgat aaccctgact
      961 tgttctttgg taacatcact gataatatct agtagctatc gttactccat gaaacagtgt
     1021 atcttttggt ctgttacact tcaaagcata ggtatcctgc tagaagcaag cttagggatc
     1081 attttaatat ctcttaaata tcaaatctct tctatcagtg ggacattttt atttataaac
     1141 ctgcttacca tatccagtat tatcattata tttgtgttaa agcagctctt tttaaagact
     1201 acagacaatt ggcttgatga gcaaacacaa accaactgga tactaaagct atctattatt
     1261 ccaatgataa gtctttctct gctactgcta cagctccttc gattaaaaga agaaccttta
     1321 tttgacttgt ttacaatact gctaacactt ggatttatca ttatcacaat cacttcgctg
     1381 tatctgtata cttacatttc agatcagcat ttacaaatgc aagacattaa cttagatagg
     1441 gtacgattcc agtcagaact gaagcattta gaaaatgtaa aggaaaatca attaagcatt
     1501 agggctctta agcatgatct acataatcaa aacattgtcc tattaggact tctggagcaa
     1561 aagcagtaca ctaaagccca acaattactg aatcataacc ttaacctgct agatgggaca
     1621 gatactttct ttaccaatga tactatttta aattatttac ttaatcaaaa agcagtcgta
     1681 gccaaaaaga atggcattgt gttagatatt cactgcctta tccctacaaa cataagccta
     1741 aagactgaag ttatttcagt cattatagga aatctacttg ataatagcat tgccgcaact
     1801 attcgcaatc aaaataaagc tgaaaaacaa atacaattaa aggtgagact ctttaaaaat
     1861 caactccaca ttgatatcga aaactttttt gatccaaaag agcttgcctc cagaagtcaa
     1921 cggaaaaaag acggattggg aattaaaaat gttcaaaaaa ttgttcaaca gtattatgga
     1981 ctataccagc aaaccataga caataacatc tataaagtca gcattatctt ctctaacatt
     2041 gttttagttt ctcaacaata gcattaaccc atcaccagct ataagcatag ctgctgccat
     2101 tccaaacaag agtgctttca aactgactac taaaaatagg aaaaatagtc cttagtatag
     2161 gtataacatc acaaaatcac acaatatcat tgctattaaa gcaacgacgt tgtgtgattt
     2221 tttagtatct taatgactca taccactttt ttcagttttt ttgctttact ggatacattc
     2281 tgcaaaaatg ctggcaaaat ttgtttggat ttgatcaaag ctaactgtca tctcttgacg
     2341 agtttgatta tgcttaagga cagcttgacc tgttttgatt tcactttcac ctagggtgat
     2401 gactaccttt gccttgaaag catcagctga cttgaattgt gctttgattt tacgtccgag
     2461 gtaatcgcgt tctacggtga acccctgacg gcgaatggcc tgtgtcaagg ctagcgccgc
     2521 cacattggcg taagccccta aaacagctat gtaaacgtcc aagccttctt cgactggcag
     2581 ttcaacgcct tgcttatcaa ggataagcaa aagacgttcc aaaccaagtc caaaaccaaa
     2641 gccaggggtt gctggtccac caaaatactc cacaagacca tcatagcgac caccagcaca
     2701 aatcgtcagc tcagactgat ccacctctgt aatgaattca aaaatcgtgt ggttgtaata
     2761 atcaagccca cgcaccatat tggtatcaat aacataagga atagcaagta cttcaagcat
     2821 gctgcgcaca gcatcaaagt gagcctgact ctcctcgtca agataatcaa gaatagatgg
     2881 ggcatttgct actgcaatct tatcctcttt ttccttggaa tcaagcacgc gcagagggtt
     2941 ttcatctaaa cggcgctgac tatccttgga caaggtctca cgcattggag ataggtaatc
     3001 aatcaaggcc tgacgatagg ctgcgcgact agctgcattt ccaaggctat tcaaatgcaa
     3061 ggtcacctct ttaataccaa gcctttcaaa gaggtgataa gccatggcga tcgtctcaac
     3121 atcagtggca ggattggcag agccaaagca ctctacacca atctggtgaa attcacgcaa
     3181 acggccggcc tgcggacgct cataacgaaa cattgaccca atataataca gcttgacagg
     3241 cttttgaacc tctggcgcaa agagcttgtt ttccacatac gaacgaacaa ctggggctgt
     3301 tccttctgga cgaagtgtga tatgacggtc gcccttatca tagaagtcat acatttcctt
     3361 ggtcacaata tcagtggtat cacctactga tcggctaatg acctcataat gctcaaacat
     3421 aggtgttcgg atttcaccat aatggtattg cttaaaggtt tcacgtgcaa caccttcaac
     3481 atattgccac ttagcagcag ccacaggcaa aatgtcctgt gttccttttg gtttttgaag
     3541 cttcatttta tttcctcttt tactagtatt tatatatttt accatagaat agcttcatta
     3601 atctgttaaa gtacagaaaa gctacgaacc aatttaccgc ctcgaatatc taaaacaatc
     3661 atatcttgaa tatctccact tcgattagat ctactcaccc tgtcaaaccc cactttatag
     3721 tagccatccc acaagcaggt aaagtctaga ctttttattc tatcagaaaa atccaacctg
     3781 gggccagaca aatcgtcttg ttcctcttct gacattcgcc aatcaaaatc tatacgaatt
     3841 tccaacacgt gatttttcaa atactttgaa acatcaatat gataatagcc acctattgat
     3901 agcccagctt ctctattatt agatgcatct tgagataatt cattcctgcc tcgtacaaca
     3961 tcttccctaa tcagctctcc atctgaatca gaaatcgtct ggacactttg tcctgttacg
     4021 gatataagct tcaaatcctc agtctccaac tcgctaaata gttgtttgat ctgagcagct
     4081 tgcgctttga cagctggttg ctgccacata gcttcttccc taattcccat gtcaacttct
     4141 gcatcagcca aatcttcctc aggtgattta taggtagcaa tcgaaatact atccttcaga
     4201 ctaataacct taccgtctac ttcttcgctg taggtaaaat aaagtctctc actacctgtc
     4261 tcaatcatct tagtatagtc gtctacagtg attttccctt ggtatcctaa ggtttgaaat
     4321 tttttaataa taatggggct atactctgtt acaacacgtt ctttttctgc ctgtgaaaca
     4381 ccacaaccag tcaaagcaac gacaaagcct aacagactta ataattttcc aaacatctta
     4441 atctcctaaa ataaccacct ttgtctcatt ttaccatttt ttaggatttt tggagaatag
     4501 cagagctttt taataaaatt tttgtcaagt aactttactt tacatagaag atatgatatg
     4561 atactaaagt tggcgaaagc cataacatca aatagataac aatgggtcaa agatttgaga
     4621 cagataggtt agcataagat catgcacacc agtttgtcac caatctttta atagaccctt
     4681 gatcatttaa cggaggatag aaaaaatggc agttcctgca cgtcacacgt caaaagctaa
     4741 aaagaacaaa cgtcgtacac actacaaatt gactgcacca tcagtaaaat ttgacgaaac
     4801 aactggagat tactcacgtt cacatcgtgt ctcacttaag ggatactaca aaggacataa
     4861 aatcgctaaa gctaacgcag ctgaataata gaagggagat accatgcgcg taaatatcac
     4921 acttgaacac aaagaatctg gtgaacgctt gtaccttact tcaaaaaaca aacgtaacac
     4981 tccagaccgc cttcaattga aaaaatactc accaaaacta cgtaaacatg ttgtgtttac
     5041 agaggtaaaa taagacgata tacagaaagc ccttgaaatc aacgtttcaa aggctttttt
     5101 gttttggttt tgatgagaca actgagtatt ctcagctaat acaataagca aaggtactta
     5161 tgatgataat ctttcatatc tgccttgggc taaaataacc tcatcagtga tctcacaatt
     5221 taactgtgga cgaaaaaccg tctgccaagg tcccttttca gagtgcgtca gcttaaccaa
     5281 ttctcctcct gttaaatctc catactgttt aacaacatct aataatacag gcacaatctt
     5341 ctttgcgtct tcgaccaata gcattctacc taaggcttgc ggaagatgta tgtcttttaa
     5401 aatatattct gtatgatcat cgatatctat cacctcagaa ccatattttt taaagctgtg
     5461 atacacctct tctactacag gaccatattg aaaagcaact attttttcat caaataagga
     5521 ttcaccatag gcaagaagat atgttttata agcaagataa actaactttt gcaattgtaa
     5581 gtgtgagagt ggacgcattg ctaagaaaaa tttagcaaca tcaatagcac taattttaga
     5641 gtcggattgt aaaacctgtt caaattcatc gaagtcttga caaaccataa tatcctcaaa
     5701 aaaggaatct aactcaatga cactttgcca atcagcacta tctgtaacaa aagaatgcac
     5761 accaacatca tctctattga tatgactcag ccgctgcatt ttttcttcaa tggcaacatg
     5821 atccaattga ccttctgtcg ctaagtgaaa gccaactctc tcacctcttg catatgaact
     5881 agcaactaaa ataaaatgct gatacatgcg gttattcctc cttttctaaa ttagcatcaa
     5941 aataatgttg gggtagtgat atatattgtc gtttttgctt atgctcttta tgtgacagct
     6001 catttaagcg tgattgctct ggatcccaaa tctgtaattc ccatggaaaa aaccgattat
     6061 ttccattttt aaaatataga tggatacctt tatagtcgcc atctgttctt aaatacaatt
     6121 tagcaatatt agtcactcga ttatcatttt gcaaagcagc aaaaacaact tctaagttat
     6181 tgaccaagat cctaaatcca agaaaatcat tcaaacattt atttaaggga atccttccaa
     6241 actcatgatt ctcgctcatg tagtataaaa gcttctcact aatagattct gcttgcttta
     6301 ttctccatct aatgcctata aactgatgtc gtatgcttga gacttgacta atattcctat
     6361 ttagccttgc tttataagaa acgatgagct cttggaactc cctatcaata cgattgttaa
     6421 cgactaccga actgacactc tttttcaaat taaagcatag aagagctcct aaacccgaag
     6481 aaaatgaata gtgtaatcga ttgatttcac taataatctc aacaacactt tcatattgat
     6541 aagctgcaat aggcaatcag aaacctccaa aaatagcaaa aaacacaagt atcacatctg
     6601 tcacctgtgc atacctctat cctactagct atagtctatc tttttaaaga atacttgtca
     6661 acatttctac acctgaaagc attttgaagc aacaatgtca gctaagccca gcgtagcctt
     6721 gccaatctta tggtttccca aacaccgata taaagctgtc atcttcatca agaatttcct
     6781 gatcagcctt gaacaagatc aattatatca tgataaaatc agacgtttaa tgattgaatt
     6841 aaaaaaaacg aaactacgga ggcgaattgc ccaaaacgta ttcacagcct gcaagcgtca
     6901 tgttaagatt ttttggaaga attttagaaa aaacattcga cgatatgtga ggactaaatc
     6961 atgaaaagac aatcaaacat cagacgcttg tgtcatcaag ccctagcagc tactctcatc
     7021 acaggaagcc tgataggaac aggactactt ggaaataaag ttgtgtatgg agatatgagt
     7081 gcggacgtaa aaaaaattga gcaagtttta caatcagata gtggtaagtt aaaaacagta
     7141 ttaggacaaa ttagtgatcc caatacattg tttgctttat ttgctattat atcagccgat
     7201 gtaaatatag atccagaaag ttttagtttt atattaaatg gcccaatcac accattatta
     7261 tcatatttca acaatccaaa caaaaatgat aatagaaagg cagttgttaa tgaaataaaa
     7321 aaaagagtct cagctttgga gcaagctcaa aaattagaaa ctaaagctaa aatagagaaa
     7381 cagattgcag aaagtgaatt agaaaaaact aggaatgctt tcaaagtaac aattgaaaat
     7441 ttacataaac tagagggatt attagacact gaaaaacaaa aaactcgaaa agttgaggaa
     7501 gattaccaac aagctaaaac cgataaagaa aaagcagagg ctgataaaag gaatgcggaa
//
LOCUS       DARYNN010000077         7522 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.077, whole genome shotgun sequence.
ACCESSION   DARYNN010000077 DARYNN010000000
VERSION     DARYNN010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7522)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7522)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7522
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.077"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(<1..375)
                     /locus_tag="TVB59_001867"
     CDS             complement(<1..375)
                     /locus_tag="TVB59_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEL1010721.1"
                     /translation="MTRQIKEVTLEPLIQAEVYSQQPYLTKADIEAAILLALKQIRLN
                     MDYFGTDFPRPATKDNCYPIMDNTEWTNGFWTGCLWLAYEYTGNDTIKSLAQANDLSF
                     LERVTKDIELDHHDLGFLYSPSC"
     gene            complement(375..809)
                     /locus_tag="TVB59_001868"
     CDS             complement(375..809)
                     /locus_tag="TVB59_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEL1010722.1"
                     /translation="MISIIVIGHGHFASGIVSSLELIAGKQEGITAIDFTAEMTAADV
                     HERLSVVLQSKTQALMLCDLLGGTPFKVAATLMEELSESTLDVLSGLNLAMLIEAVFA
                     RQEQLDLEQIVAKLLTTAKEGISNWKSLSGEADEADLDEGGI"
     gene            1118..1912
                     /locus_tag="TVB59_001869"
     CDS             1118..1912
                     /locus_tag="TVB59_001869"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEL1010723.1"
                     /translation="MEHFFSLEGKIALITGASYGIGFEIAKAYAMAGAKIVFNDIKQD
                     LVDQGLAAYREFGIKAHGYVCDVTDEVGIQEMVAQIEKEVGIIDILVNNAGIIKRTPM
                     LEMTAKDFRQVVDIDLNAPFIVSKAVLPSMIKKGHGKIINICSMMSELGRETVSAYAA
                     AKGGLKMLTKNIASEFGEANIQCNGIGPGYIATPQTAPLRERQADGSRHPFDQFIIAK
                     TPAARWGTPADLAGPAIFLASEASNFVNGHILYVDGGILAYIGKQP"
     gene            1947..2588
                     /locus_tag="TVB59_001870"
     CDS             1947..2588
                     /locus_tag="TVB59_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEL1010724.1"
                     /translation="MKIALINENSQAAKNSIIYETLVSVTNKHGYEVFNYGMYGKEGE
                     SQLTYVQNGLLASILLTSKAADFVVTGCGTGVGAMLALNSFPGVTCGFASEPTEAYLF
                     AQINGGNALSIPFAKGFGWGAELNLTLMFERLFAEPMGGGYPKERAIPEQRNARILSE
                     LKAVTYRSLLEVLKEIDQDFLKETISGEHFQHYFFANAEPSDLVDYLREVLQQ"
     gene            2621..3622
                     /locus_tag="TVB59_001871"
     CDS             2621..3622
                     /locus_tag="TVB59_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEL1010725.1"
                     /translation="MTKVLLVGEPLIRISPSHFQTLGHACQAQLYYGGSEVNIARTLS
                     GFRAESSLLTALPDNQVGRSVEAFLKQSGVATEHVQWCGDRVGIYYLENGFGCRPSQV
                     AYDRSASSFSLLGPKDLDYGKLFEEVTHFHFSGITLALGKVSQDLVEQLAIEAMKRQV
                     CVSFDLNFRSSMISVREAKTLFSHFAQYADLIFGMEPLMCNQADHAMFDRAKAGQGAV
                     KERLAALYEAYHLKAIFHTERHIDDQGINHYLAYAYDGQLHRSIELSTPVLQRVGSGD
                     AFVAGCLYQLMRGQAIAAALDFAAATASLKCTVADDQLFVPVSQVDRVMKGNREVRR"
     gene            3624..4253
                     /locus_tag="TVB59_001872"
     CDS             3624..4253
                     /locus_tag="TVB59_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEL1010726.1"
                     /translation="MRKSEIMLRLKANKLALVVRGASKKEAMACSLAGIEGGIKTIEV
                     AYTNPFASQVIAGLREAVGNDPEILIGAGTVLDDVTARLAILAGAQFIVSPSFSRQTS
                     RLCHRYAIAYIPGCMTIEEVVTALESGAEMVKVFPGATVGMSFIKAIKSPLPQVDVMV
                     TGGVTVTNVSDWFAAGAQVLGVGGEFNQLAAQGQFQAITARAADYMSSC"
     gene            4293..4946
                     /locus_tag="TVB59_001873"
     CDS             4293..4946
                     /locus_tag="TVB59_001873"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010727.1"
                     /translation="MKQRKKLSSSVCSSIILACLFRAPTVLAEEKTAAKAISKELQRV
                     KKAPLKTEEASQESSPDTQDASSVATESSLGEQLILTGDNLLKNPQFDQTSPAQEHQS
                     TSLWSKESANDWKDYKDASKSQGCPKIAVSDNKLTMTSDGNQRFRGCVHQTVAINPDK
                     QYLLTFDIETKDKTGQAFARIIEEIKQGSGAAKEQRLWLRWQQELRKNTKKSFISLS"
     gene            4892..7480
                     /gene="hylB"
                     /locus_tag="TVB59_001874"
     CDS             4892..7480
                     /gene="hylB"
                     /locus_tag="TVB59_001874"
                     /EC_number="4.2.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_192884538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronate lyase"
                     /protein_id="HEL1010728.1"
                     /translation="MATGTEKKHQEKLYIPKLKVNQIKLELFYEAGHGQVVFDNLSLR
                     EAGDKPSDDIKIASHYLEEQIVLPLNKHYLMEMADYHYQIAAESSNIVRVENGLLIPL
                     AQGKTLLEVLDQEGQRVATVPVEILAAEAPQTTSLITKWCEVILGAENFDRSSPAMVA
                     LNQKLDDSVTKNLADLTKDQKSTYLWSDLADLHQSSHMTATCRRLEEMAKQVSSLASR
                     YYQDKELIRLIKDKLAWLTLNYYHPQKDIEGKANWWDFEIGTPRAIVNTLAFIYPYVT
                     QEEIKRYTKGISHFVPNPRQFRLTLVNPFKAIGGNLVDMGRVKIIEALLKHDKKALQD
                     SIAALDTLFAFQPKGSRGEGFYEDGSYIDHTNVAYTGAYGNVLIDGLSQLVPLLQLLA
                     TSLDQQKLEVMTHWIEQAFLPLMVHGELMDMSRGRSISRENASSRQAALEALRGMLRL
                     AEALPEQAKIRIKGKIKAVLAFHNQETILESLSSYYDMKLFKELLEDTTIQASPVKSY
                     LSLFNQMDKLAYYNAEKDFAFALSMHSNKTLNFEAMNDENTRGWYTGDGMFYLYNSDL
                     GHYSDHFWPTVNPLKMAGTTEAEVRREDVTVAYLKKLTNDYKEKAKEKAGMSTLPSSF
                     VGAIKAGDKTALAVMDFQNWDRTVSAKKSWTILDDQIVFLGTAITSQTHQAVTTTIDQ
                     RKENPDNSYTLFINGQETALTEEILYRDDVTSLLLLSKDGQANIGYLFAKPTALALSR
                     KVQSGCWSEINTNSNNKDLISQSFITISQTHSQASDSYAYTLLPNISKADFDKVCSEA
                     RIEVLRNDSKLQLIHDKKQGLLAVVKYNQAKEVVNGQLSLEKSGLYLYQKVGNDFKQL
                     SFKALS"
BASE COUNT         2178 a         1476 c         1802 g         2066 t
ORIGIN      
        1 gcaagagggt gaataaagaa atcctaaatc atgatggtca agctcaatgt ctttggtgac
       61 gcgttctaag aaggacaggt catttgcctg tgctagtgac ttgatagtgt cattaccagt
      121 gtattcgtag gccagccata ggcagccggt ccaaaagcca ttggtccact cggtattatc
      181 cataattggg tagcaattgt ccttagtggc tggcctaggg aaatcagtac caaaataatc
      241 catgtttaat cggatttgct taagggctaa taaaatagct gcctcaatat cagcttttgt
      301 tagatatggc tgctggctat agacctctgc ttgtatgaga ggctcaaggg taacctcttt
      361 gatctgtcta gtcattaaat ccctccttca tcaaggtctg cttcatcagc ctcaccagag
      421 agggatttcc aattactgat cccttccttg gctgtggtta atagcttagc gacaatttgt
      481 tctagatcaa gctgctcttg cctagcaaag actgcttcta ttagcatggc tagattgagt
      541 ccagacagga catcaagtgt gctctcagaa agctcctcca tcaaggtagc tgctacctta
      601 aatggggtgc cgcctaataa gtcacaaagc ataagtgcct gagtctttga ctgtaagact
      661 actgataggc gctcatgcac atcagcagcg gtcatctcag cagtaaaatc aatagcagtt
      721 atgccctctt gcttgcctgc aattaactct aaagacgaga caataccact ggcaaaatgc
      781 ccatgaccaa taacaataat agaaatcatg aataagctcc tttttagttt accggtttac
      841 tcagaaaaat tatagcgctt tcaaaaatgt ttgtcaacac ttttttgtta ttttatcaaa
      901 ataagcgatc aatatggcct aatttttggg atccttatag gaagtaaagc gagtaagagc
      961 aagaaaaata tagctaagaa gccttcctcg ataatgacaa taagaaaaac tttagctctt
     1021 ttttgtgttt ttactaaaat gattgacaaa atggattagt cttgctatag ttttgataaa
     1081 caggtttact taaatattga gattgagagg taaaacaatg gaacatttct tttctttaga
     1141 gggcaaaatt gccttgataa cgggagcctc gtatgggatt ggctttgaga ttgctaaggc
     1201 ctatgccatg gctggagcaa agatcgtctt taatgacatc aagcaggatt tagtggatca
     1261 aggattagca gcttatcgag agtttggcat taaagctcat ggctatgttt gtgatgtcac
     1321 tgatgaagta gggattcaag agatggtggc tcagattgaa aaagaggttg gtattattga
     1381 tattcttgtg aataatgcag gtatcattaa acggacaccg atgcttgaga tgacggctaa
     1441 ggattttcgt caggtggtag atatagacct gaatgcgcca tttattgttt caaaggcagt
     1501 tctgccatca atgattaaaa aagggcatgg gaaaatcatc aatatctgtt cgatgatgag
     1561 tgagcttggt cgtgaaacgg ttagtgctta tgcggcagct aagggtggtc ttaagatgtt
     1621 aaccaaaaac atcgcttcag aatttggaga agccaatatc cagtgcaatg gcattgggcc
     1681 tggctatatt gcaacgcctc agacagcacc tttaagagag cgtcaggctg atggcagccg
     1741 tcaccccttt gatcagttta ttattgctaa gactccggca gcgcgttggg gaacaccagc
     1801 agatctggct ggtccagcta tatttttggc tagtgaggcg agtaactttg tcaatgggca
     1861 tatcctttat gttgatggag gcattttagc ttacattggc aaacaaccgt aaagaaacaa
     1921 aaaagcatca aaggagatta cagaagatga aaattgcatt aattaatgaa aacagtcaag
     1981 cagctaaaaa cagtattatt tacgagacct tagtctctgt tactaataag catggctatg
     2041 aggtctttaa ctatggtatg tatggcaagg agggcgaaag tcagctgacc tatgtgcaaa
     2101 acgggctact agcttctatt ttattgacaa gtaaggcagc tgattttgtt gtaacgggct
     2161 gtgggactgg tgtgggtgct atgctggcct taaatagctt tccaggtgtg acctgtggct
     2221 ttgctagtga gccaacagaa gcctaccttt ttgctcagat taatggtggc aatgccttgt
     2281 ctattccatt tgcaaagggc tttggttggg gggcagagct taacctgacc ctgatgtttg
     2341 agcgcttatt tgctgagccg atggggggcg gctatcccaa agagcgggcc atcccagagc
     2401 aacgtaacgc tagaattttg agcgaattga aggctgtgac ttatcgttct ttgttggagg
     2461 tgttaaagga gattgatcaa gatttcttga aggaaaccat ttctggagag cacttccagc
     2521 attatttctt tgctaatgcc gagccatcag accttgtcga ctacctaaga gaagtccttc
     2581 agcaataagt cttatctgca gctatagaaa ggatacccct atgaccaagg tattattggt
     2641 gggagagccg ctgattcgca tcagtcccag tcattttcag acgttaggac atgcctgtca
     2701 agcacagctg tattatggtg gctcagaggt taatattgca agaacgctta gtggctttag
     2761 agcagagagt agcctgctga ctgcccttcc tgataatcag gttggacgaa gcgttgaggc
     2821 ctttttgaag caaagcggtg ttgccacaga gcatgtgcaa tggtgtggtg atcgggttgg
     2881 tatttattat ttggaaaatg gctttggctg ccgtcctagt caggtcgctt atgatcgctc
     2941 tgcctctagc tttagtttat tgggcccaaa agatctggat tatggtaaac tatttgagga
     3001 agttactcat tttcatttta gtggcattac cttggcttta ggaaaagtca gtcaggacct
     3061 tgttgagcag ctggctattg aggcaatgaa gcggcaggtc tgtgtttcct ttgatttgaa
     3121 ttttcgcagc tcgatgattt cagtcaggga ggcaaagaca ttgttctctc attttgcaca
     3181 gtatgcagac ctgatctttg gtatggagcc cttaatgtgt aatcaagctg atcatgccat
     3241 gtttgataga gctaaggcag gtcaaggtgc tgtcaaggag cgcttggctg ccttatatga
     3301 ggcatatcac ttaaaagcca tttttcacac ggaacgtcac atcgatgacc aaggaatcaa
     3361 tcattaccta gcctatgcct atgatgggca gttacatcgc tccattgagc tatcaacgcc
     3421 tgttttgcaa cgagttggca gtggtgatgc ctttgttgca ggctgcttat atcaattgat
     3481 gagaggacag gctattgctg ctgcgcttga ttttgctgct gcgacagcta gtcttaagtg
     3541 tacagttgct gatgatcagc tctttgttcc tgttagtcag gttgataggg tgatgaaggg
     3601 aaaccgagag gtaagaaggt aatatgagaa aatcagaaat catgttaagg ctaaaagcca
     3661 ataaattagc cttagtcgtt cggggagctt ctaaaaaaga agcaatggct tgcagcctag
     3721 caggtattga aggtgggatc aaaaccattg aggtggccta tactaatccc tttgccagtc
     3781 aggttattgc aggcctgcgt gaagcagttg gcaatgatcc agagatcctg atcggggctg
     3841 ggacggttct tgatgatgtc acagcaaggc tagctatttt agcgggtgct caatttattg
     3901 tgtctcctag ctttagcagg cagacaagcc gcctatgtca tcgatatgct attgcttata
     3961 ttccgggctg tatgactatt gaggaggtcg tgactgcctt ggaatcaggt gcagagatgg
     4021 tcaaggtctt tccaggtgcc acagttggca tgtcctttat taaggcaatc aaatctcctt
     4081 tgccgcaggt tgatgtcatg gtaacaggtg gcgtaactgt cacaaatgtg tcagactggt
     4141 ttgccgcagg tgctcaggtg ctgggagttg gaggagaatt taatcaattg gcagctcagg
     4201 gtcaatttca ggcaatcaca gcaagggctg cagattacat gagtagctgt taaagtcggt
     4261 cataaaacat taaaaaagca aggaggtatc agatgaagca aagaaaaaaa ctatcatctt
     4321 ctgtttgctc tagtatcata ctagcttgtt tatttcgggc accaacagtc ttagcagaag
     4381 aaaaaacagc agcaaaagcc atttccaagg agcttcagag ggtaaagaaa gcaccactaa
     4441 aaactgagga ggcttctcaa gaaagctccc cagacactca agacgcgtcg tcagtagcta
     4501 cggaatccag tcttggggag cagctcattc tcacaggtga taacctgctt aaaaatcctc
     4561 aatttgatca gaccagtcct gctcaagagc atcaaagtac aagcctttgg agcaaggagt
     4621 ctgcaaatga ttggaaggat tataaggacg ctagtaagag tcagggctgt cctaaaattg
     4681 ctgtctctga taacaagctg acaatgacta gcgatggcaa tcagagattt agaggctgtg
     4741 tgcaccaaac cgttgccatc aatccagaca agcagtattt gctgaccttt gacattgaga
     4801 caaaggataa aacaggtcag gcttttgcgc gtatcattga agaaataaag caaggttctg
     4861 gtgctgcaaa agagcaacgc ttgtggcttc gatggcaaca ggaactgaga aaaaacacca
     4921 agaaaagctt tatatcccta agctaaaggt taatcaaatc aagctagagc tcttttatga
     4981 ggccggtcat ggacaggtgg tctttgataa cctttctttg agagaggctg gtgataagcc
     5041 aagtgatgac atcaagattg cttcacatta cttagaggag caaatcgtcc tgcctttaaa
     5101 taagcactac ctcatggaaa tggctgacta tcattatcag attgcagcgg agtccagcaa
     5161 cattgtgcgc gtggaaaatg gtcttttaat tcctttggcg caggggaaaa cgcttttaga
     5221 ggtgttggat caagaggggc aaagagtagc aacggtacca gttgagattt tagcagcaga
     5281 agcccctcaa acaacctcct tgatcacaaa gtggtgtgag gtgattttgg gagcagaaaa
     5341 ctttgaccga tcaagtccag ccatggtggc attaaaccaa aaactggacg acagcgtgac
     5401 caagaatcta gctgatctga ccaaggatca gaaaagcaca tacctttgga gtgatttggc
     5461 ggatcttcat caatcgtctc atatgacagc tacctgtagg cgtttagagg aaatggccaa
     5521 gcaggtgagt agcctagcct ctaggtatta tcaggataag gagctgataa gactgatcaa
     5581 ggataaatta gcctggctga cacttaatta ctatcatccg caaaaggata ttgaaggcaa
     5641 ggctaattgg tgggattttg aaattggtac cccaagagct attgtcaata ccctagcctt
     5701 catttaccct tatgtcactc aagaggagat caagcgctat actaaaggaa tttctcactt
     5761 tgttcctaat cctagacaat ttcgcttaac ccttgtgaat ccttttaagg ccattggggg
     5821 taaccttgtt gatatgggac gagtgaagat tattgaagct ctgttaaagc atgataagaa
     5881 agcgcttcaa gacagtatag cagccctaga taccttattt gcttttcagc caaagggatc
     5941 aaggggtgag ggcttttatg aagatggctc ttatattgac cataccaatg tcgcctacac
     6001 tggagcctat ggcaatgtcc ttattgatgg cttgtctcag ctggtaccat tacttcagct
     6061 attagctact agcctagacc agcaaaagct agaggtcatg actcattgga ttgagcaagc
     6121 cttcttgccc ttgatggttc atggggagct catggatatg agtcgtgggc gctccatcag
     6181 tcgtgaaaat gcctcctcaa ggcaggcagc cttagaagca ctaagaggaa tgctaagact
     6241 ggctgaggca ttgccagagc aagctaaaat caggatcaag ggtaagatca aggctgtttt
     6301 ggccttccat aatcaggaga ctattttaga gagcctatca agctactatg acatgaagct
     6361 attcaaagag ctcttggagg ataccacaat ccaagccagt ccagttaaga gctacctatc
     6421 tctttttaac cagatggata aattggccta ctacaatgcg gaaaaggatt ttgcctttgc
     6481 tttatccatg cattccaaca aaactctgaa ttttgaagcc atgaacgatg aaaatacacg
     6541 tggttggtat acaggagatg gcatgtttta cctttataac agtgatttgg gtcattactc
     6601 agaccacttt tggccgactg ttaatccttt aaagatggct ggaacaacgg aagcagaggt
     6661 caggcgagag gacgtgacag tagcctattt aaaaaagcta accaatgatt ataaagaaaa
     6721 ggccaaagaa aaagcaggca tgtctaccct gccatcgtcc tttgttggag cgatcaaggc
     6781 gggagacaaa acagctttag ctgttatgga ttttcaaaat tgggatagga cagtgagtgc
     6841 caagaagtct tggacgatct tagatgacca aattgttttt cttggcaccg ccatcactag
     6901 tcagacacat caggcagtga ctactaccat tgatcaacgc aaagaaaacc cagacaacag
     6961 ctacactctt tttatcaatg ggcaggagac agcgctaaca gaggagatcc tgtatcgaga
     7021 tgatgtgacc agtcttttac tactttctaa agacggtcaa gctaatattg gttacctttt
     7081 tgccaagcca accgcattag cgctatcgcg aaaggtgcag tcaggctgtt ggtctgagat
     7141 taatacaaat agtaacaata aagacctcat ctcccaaagc tttatcacaa tcagtcaaac
     7201 tcattctcag gctagtgata gctatgccta caccctactt ccaaatatca gcaaagcaga
     7261 ctttgacaag gtgtgcagcg aagcacgtat tgaggtgctt cgaaatgaca gtaagcttca
     7321 gctgatccat gataagaaac aaggcctgtt ggcggtggtc aaatacaatc aggctaagga
     7381 ggtggttaat ggtcaattga gtcttgaaaa atcaggctta tacctctatc aaaaggtggg
     7441 aaatgacttt aagcagctat cttttaaggc cttatcatag ccattcaagc acattagtaa
     7501 taagttaaaa tcccccctga gc
//
LOCUS       DARYNN010000078         7495 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.078, whole genome shotgun sequence.
ACCESSION   DARYNN010000078 DARYNN010000000
VERSION     DARYNN010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7495)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7495)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7495
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.078"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            436..975
                     /locus_tag="TVB59_001875"
     CDS             436..975
                     /locus_tag="TVB59_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010729.1"
                     /translation="MRQLIAAMVEKNQDLPRNILVAEMSLEKAVQPDDYRVKDYRNLR
                     QIRLTTSGLVLEVRLLKGLPARWLKKDTSAKPSKAVNSRALAEHSHVLSVNQAALQQF
                     LAETGDQNPLHQTAPYILPGALLMEEVSSWLTLDYRRLSLRFYAPAVVNAPIHLVMRE
                     KAISLYQAGELVAKGELHV"
     gene            972..2087
                     /locus_tag="TVB59_001876"
     CDS             972..2087
                     /locus_tag="TVB59_001876"
                     /EC_number="2.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acyltransferase"
                     /protein_id="HEL1010730.1"
                     /translation="MIDVYIQRGLRTPIGLAGKQFARVRPELLGAQLINALVKADKLA
                     IDEVICGNAVGTGGNIGRLMTLYSDLGETVPAITVDMQCASAGAALTMGYAKIKAGLA
                     TSLLAGGIESSSLQPQRIYAAADSRSGAYQVAQFSPDTSSQLAMIAGAERVAQAYQMT
                     PSQLNQWTLTSHQRAHIARQKHWLADIILAMPGMSDQGIRPRLSEKVLSKVPPILDKA
                     GLISAANTCLTHDAAAFLVLSNQRSAYQILDLVEVAGNPKTSPQMVVEASQVLLARNG
                     LAMTDMDAIEWNEAFAVIDLLFEHYFVEALDRYNIFGGALAYGHPFGASAAIIILHLM
                     QALALKQGKYGLAAIPAAGGQAFALLLEYHKDYSHAI"
     gene            2077..3339
                     /locus_tag="TVB59_001877"
     CDS             2077..3339
                     /locus_tag="TVB59_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HEL1010731.1"
                     /translation="MLSRLLAWASQAPQRPAILTDQKTLTYQDLVEQILAYQPQESIS
                     YPTLIVKRDCFQQLIAFCYHLQHGNYPLICHPNLPEQEQRRLSSCDPPSDKAAFAVLS
                     SGSTGRPKVFWRSWASWSNFFEQQNQLFYFSEQTRLFSHGSLSFTGNLNLALAQLWAG
                     GCLVFSDQRSFKGWSSVWRRQKVTHLYLLPSLLQRLLPYFSADSYFAPYLLTSSQHLS
                     PELIRSYYQRFPRLELLMFYGASELSFISWCQGFEAMAIAGFVGRPFPQVKLELREGH
                     IFVQTPYAIEGIEQPYSVDDVGEMTAAGLILKGRTKDWVNQQGVKCHLPSLVQLVHQS
                     GVVQEAAAIKGGSSAADEHVILCLVLKKQGSLTAVKAYLEAHLSPAQRPKRYILLKEL
                     PLNDSGKLDSRRLSQLAHKSTKAAHNTK"
     gene            3385..4404
                     /locus_tag="TVB59_001878"
     CDS             3385..4404
                     /locus_tag="TVB59_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3114 domain-containing protein"
                     /protein_id="HEL1010732.1"
                     /translation="MVKKGGQLMKQDMLARYQALKPYVRAGLSSTSQQLLAAASAIDA
                     RLGSPTFLAIWQCEKQCRSPKELLGLVLDLVGMPIELSGRLEDTQALLSRFYPDLPPD
                     HCFWVELAQMVSLAFPDKELAQQSALAKGLHQLRYLISSQQAQYIRSHFRSEDMTDAQ
                     ALAIFLKDKKGPAFWRSQPDYTLMESARLHNKLKLVNGLASFPDHEISHNIKILLHFH
                     TEFILDSQGCFLNEIDGEVVTNKGIINGASFNYGTAGKRHWELDVAPISRHDPTFRKK
                     CLVGHQAPKWLKRSWLQLSPLDFDYSYFNAKGFFSLNSKSCFALVKRQARAFRWQIWR
                     SRFFK"
     gene            4603..5313
                     /locus_tag="TVB59_001879"
     CDS             4603..5313
                     /locus_tag="TVB59_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019321978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1010733.1"
                     /translation="MKKILIVDDEKPISDIIKFNLTKEGYDTVTAFDGKEAVAVFEEE
                     KPDLIILDLMLPELDGLEVAKEIRKTSHIPIIMLSAKDSEFDKVIGLEIGADDYVTKP
                     FSNRELLARVKAHLRRTETIETAVAEENASSGSQELTIGNLQILPDAFIAKKHGQEVE
                     LTHREFELLHHLANHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSR
                     PEYILTRRGVGYYMKAYD"
     gene            5306..6658
                     /gene="vicK"
                     /locus_tag="TVB59_001880"
     CDS             5306..6658
                     /gene="vicK"
                     /locus_tag="TVB59_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEL1010734.1"
                     /translation="MTKDIIGNLSAFELAILLLLVFVAFYFIHLAIRDYRNARIIRLM
                     SHKIRDLINGRYTDTINEKADIELMELSEQLNDLSDVFRLTHENLAQEKNRLASILAY
                     MTDGVLATNRSGKIIMINETAQKQLNLNREQALEKNITDLLDSDSPYTYRELVSKTPI
                     VTLNRRNDTGEFVSLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALKEDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNHVT
                     QLSVEMTNFTAFMTSILNRFDLVKNQHTSTGKSYEIVRDYPITSIWLEIDNDKMTQVI
                     ENILNNAIKYSPDGGKIIVNMKTTDTQLIISISDEGLGIPKKDLPLIFDRFYRVDKAR
                     SRAQGGAGLGLAIAKEIIKQRRGFIWAKSDYGKGSTFTIVLPYEKDAAIYDEWEDDID
                     "
     gene            6662..7471
                     /locus_tag="TVB59_001881"
     CDS             6662..7471
                     /locus_tag="TVB59_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEL1010735.1"
                     /translation="MSEVGFKYSILASGSTGNCFYLETPKKRLLIDAGLTGKKITSLL
                     AEIDRRPEDLDAILITHEHSDHIKGVGIMARKYNLDVYANEKTWQMIDERHMIGNLDV
                     AQKHVFERGKTMTFGDIDIESFGVSHDAVDPQFYRIMKDNKSFVMLTDTGYVSDRLAG
                     IIENADGYLIESNHDVEILRAGSYPWSLKQRILSDLGHLSNEDGAGAMIRSLGNKTKK
                     IYLGHLSQENNIKELAHMTMVNQLAMADLGVGTDFTVHDTSPDTACPLTDI"
BASE COUNT         2020 a         1599 c         1798 g         2078 t
ORIGIN      
        1 cctcggcacg atagtcctga acccttgttt cagcctactt cttcactgtc ctaagatcgc
       61 ttttaggatg gccttgccaa gtctaggcct tagttggagt accgtaacat tcgcagcagc
      121 ctttatcagc taatgtctta gaatgataat aggtcatgcg acttatctag cgcgtgaatg
      181 accttgaagc ttgccttgtg tgctttcttc tgtctatttc aagtagagct gaatgactat
      241 cagttacctg taggcagagg ctgtagcagc cttgatttat taaatgatat tgaacatgat
      301 gtgatcagac aaaaaaggtt aggctaaagg ctcgcctttt tttgctaact aagccttgtt
      361 tttgctgttt tttcttttct tgtgttcagg tattcagtat aataaagtta acttgttcgc
      421 aaaaggatgg ttacaatgag acagctaatc gcagctatgg ttgagaaaaa tcaggattta
      481 ccaagaaaca tccttgtggc tgagatgagc ttggaaaaag ctgtgcagcc agatgattat
      541 cgcgtaaagg attatcgaaa tctgcggcag atcagattga ctacatcagg gcttgtgcta
      601 gaggttcgat tactaaaagg gctaccagcc aggtggctga aaaaggacac aagtgctaag
      661 ccttctaaag cagttaatag ccgagcatta gctgagcata gccatgtact gagcgttaat
      721 caggcggcct tacagcaatt tctagcagaa acaggagatc aaaatcctct tcatcaaaca
      781 gctccctata tcttaccggg agccctcttg atggaagagg ttagcagctg gcttacttta
      841 gattaccgta ggctaagcct gcgtttttat gccccagcgg ttgtgaatgc tcctattcac
      901 ctagtgatga gagaaaaagc tatcagcctc tatcaggcag gagaattagt cgcaaaagga
      961 gagcttcacg tatgattgat gtctacattc aaagagggct tagaacgcct attggtctag
     1021 ctggcaagca atttgctagg gtgcgtccag aactgcttgg tgctcagctg attaatgcct
     1081 tagtcaaagc agataagctg gctattgatg aggtgatctg cggtaatgct gttgggacag
     1141 gcggtaatat tggccggctg atgactctgt attctgactt gggagagacc gtacctgcca
     1201 taaccgttga catgcaatgt gcctcggctg gtgcagctct tactatgggc tatgctaaaa
     1261 tcaaggcagg tcttgccact agcttgttag caggagggat cgaaagcagc tctttgcagc
     1321 ctcagcgtat ctatgctgct gctgatagcc gatcaggtgc ttatcaggta gctcagtttt
     1381 caccagatac cagtagccag ctggctatga tagcaggagc agagcgggtg gctcaggcct
     1441 accaaatgac cccctcacag ctcaaccagt ggacccttac tagccaccag cgagcacaca
     1501 tagctaggca gaagcattgg ttagctgata ttatattagc aatgccagga atgtctgatc
     1561 aaggcattcg ccctcgcctg tcagaaaagg tcttgagcaa ggtgccgccg atacttgata
     1621 aggctggcct catcagtgct gctaatacct gcttgaccca tgacgcagca gcatttttag
     1681 tgctaagcaa tcaaagatca gcctatcaaa tccttgatct tgttgaggtt gctggcaatc
     1741 ctaaaaccag tcctcaaatg gtggttgagg ccagtcaggt cttattagct agaaacggcc
     1801 tagccatgac ggatatggat gcgatcgagt ggaatgaagc ttttgcagtg attgatctgc
     1861 tttttgagca ttattttgtg gaggcccttg atcgctacaa tatttttgga ggcgctcttg
     1921 cctacggtca tccctttggc gcgtcagcag ccattatcat tttgcatcta atgcaggctt
     1981 tggccttaaa gcaaggaaag tatggtttag cagccattcc agcagctggt ggtcaagcct
     2041 ttgccctgtt attggaatat cataaggact actcacatgc tatctagact gctagcttgg
     2101 gcaagccaag caccacaaag acctgctatc ctaacagacc aaaaaaccct aacctatcag
     2161 gatcttgtag agcagatctt ggcttatcag cctcaggagt ctatctccta tccgaccctg
     2221 attgtcaaaa gggattgctt ccagcagctg attgcttttt gctatcattt gcaacatgga
     2281 aactacccac ttatctgtca cccaaatcta ccagaacaag agcaaaggcg tctgtctagc
     2341 tgcgatcctc catcagacaa ggcggctttt gcggtgctta gctctggctc tactggccgt
     2401 cccaaggttt tttggcgctc ctgggcttct tggtctaatt tttttgagca gcaaaaccag
     2461 ctgttttatt tctcggagca aacaaggcta tttagccatg gaagcttgag ctttacaggc
     2521 aatttgaact tagctctggc gcagctctgg gccggaggct gtctggtctt tagtgatcag
     2581 cggtccttta agggctggtc ctctgtttgg cgcaggcaaa aggttactca tttatatctc
     2641 ttaccgagtc tgctacagcg gctactgcct tacttttctg ctgatagcta ttttgccccg
     2701 tatttattaa cctcatctca gcacttgtca ccagagctga ttcgcagcta ttaccaacgc
     2761 tttccgcggc ttgagttgtt gatgttttac ggtgccagtg agctttcctt tatcagctgg
     2821 tgtcagggct ttgaggctat ggcaatagct ggctttgtag ggcgtccctt tcctcaggta
     2881 aagctggagc tccgagaggg gcacattttt gttcagactc cctatgccat tgagggcatt
     2941 gagcagccct atagtgtcga tgatgtgggg gaaatgacag cagcaggctt gattctaaag
     3001 gggcgaacca aggactgggt gaatcagcaa ggtgtcaaat gccatcttcc tagccttgtt
     3061 cagctagtcc accagtcagg agttgttcaa gaagcagcag cgataaaggg tggcagcagt
     3121 gcagctgatg agcatgtgat cctgtgcttg gtgttgaaaa agcagggaag ccttaccgct
     3181 gttaaggcct atcttgaggc gcacctaagc ccagctcaga ggcctaaacg gtatatactc
     3241 ttaaaggagc taccacttaa tgacagtgga aagcttgata gcagaaggct tagccagctc
     3301 gcccacaaat caactaaagc tgctcataac accaaataag gaaaagtcac ctgagcccaa
     3361 agcatcagct caatatggta taatatggtc aaaaaaggag gtcagttgat gaagcaggat
     3421 atgttagcac gttatcaggc actcaagcct tacgtaagag caggtctttc ctcgacctct
     3481 cagcagctat tggcagctgc ctcagctatt gatgctcgct taggctcacc gaccttttta
     3541 gccatttggc agtgtgaaaa acagtgtcga tctcccaagg aattactagg gcttgttcta
     3601 gatcttgtcg gcatgccaat agagttatcc ggaaggctag aggatacgca ggctctgctg
     3661 agtcgctttt atcctgactt gccaccggat cattgctttt gggtggagct agcccagatg
     3721 gttagtcttg cttttccgga taaggagcta gcgcagcaga gcgcgttagc taagggtctt
     3781 catcagcttc gctatctcat ttcgagccag caggcacaat atattcgcag ccattttaga
     3841 tcagaggaca tgactgacgc tcaggcactg gctatctttc tcaaggataa aaaaggccca
     3901 gctttttggc gcagccagcc tgactacacg cttatggaat cggctcgtct gcataacaag
     3961 ctaaagcttg tcaatggatt agcaagcttt cctgatcatg agatttccca taatattaaa
     4021 attctgttgc atttccatac cgaatttatc ctcgatagtc aggggtgttt tcttaatgaa
     4081 atagatggtg aagtggtgac caacaaggga atcattaacg gagcctcctt caattatggc
     4141 acagcaggca agaggcattg ggagctagat gttgctccta tcagccgaca tgacccgacc
     4201 tttaggaaaa aatgcttagt aggccaccaa gctcctaagt ggctgaagcg ctcttggctt
     4261 cagttatcgc cactagattt tgactattct tattttaatg ctaagggctt ttttagcctc
     4321 aatagcaaaa gctgctttgc cttggttaag cgacaggcac gtgcctttag atggcagatc
     4381 tggcgtagca gattttttaa gtaatggatc agtagctggc ttgcttgatg aggtatttag
     4441 agagcgtttt tgtggctagt atagtggtca ttgtcaattt ctcctaaatt ttgatataat
     4501 caaaaggaca taataaaatg atcggtctcg tctctaaatc cttatggaat agggattagg
     4561 cagcgtagca attaatgaag agaaatgttc tgaggtataa gcatgaagaa aatactgatt
     4621 gttgatgatg aaaagccgat ttctgatatc attaaattta atctgacaaa ggaaggctat
     4681 gatacggtca cagcatttga tggcaaagag gccgttgcag tctttgaaga ggaaaagcca
     4741 gatttgatta ttttggattt gatgcttcct gaattagatg gccttgaggt agccaaggaa
     4801 atccgcaaga ccagccatat tcctatcatc atgctatctg ctaaggatag cgaatttgat
     4861 aaggtgattg gacttgaaat aggggccgat gattatgtga ctaagccctt ttcaaatcgt
     4921 gagctgctgg cgcgtgtcaa ggcacatttg cgtcggacag agactattga gacagcagta
     4981 gccgaagaaa atgcctcctc aggctctcag gagctaacca tcggcaatct acagatttta
     5041 ccagatgcct ttatcgctaa aaagcatggt caagaggttg agctgaccca tcgtgagttt
     5101 gaattgctgc atcatctggc aaaccatatc ggacaggtca tgacacgtga gcatttgctt
     5161 gagaccgtat ggggctacga ttattttggc gatgttcgaa ccgttgacgt tactatccgt
     5221 cgcctgcgcg aaaaaataga ggatacaccg agtcgtccag agtatatttt gacaagacgt
     5281 ggtgttgggt actacatgaa ggcttatgac taaggacatc attggaaacc tttctgcatt
     5341 tgagctagcc atactcttat tgcttgtttt tgttgctttt tatttcattc atttagccat
     5401 tcgtgattat cgcaatgctc ggatcattcg tctgatgagc cataagataa gagatttgat
     5461 caatggtcgc tatactgata cgatcaatga aaaggctgat attgaattga tggagctgtc
     5521 tgagcagctc aacgacctat cagatgtttt tcgtctgacc catgaaaacc ttgcccaaga
     5581 gaaaaatcgt cttgctagta ttttggctta tatgacagat ggggtccttg cgaccaatcg
     5641 ttccggcaag attatcatga ttaatgagac tgctcaaaag cagctcaatt taaatcgtga
     5701 gcaggcgctg gaaaaaaaca ttacagattt attagacagt gactcacctt acacctaccg
     5761 agagctggtc tcaaaaacac cgattgtgac cttaaatcgt cgtaatgaca caggagagtt
     5821 tgtttcgctg cggctgcgtt ttgcgcttaa taggcgagag agcggcttta tttcaggtct
     5881 agttgttgtg cttcatgaca cgactgagca ggaaaaggag gagcgtgagc gcagactctt
     5941 tgtctcaaat gttagccatg agcttcgcac acctttgacc tctgtcaagt catacctaga
     6001 ggctctagat gagggcgcgc taaaggagga catagcccca agctttataa aggtctcact
     6061 agacgaaacc aatcgcatga tgcgcatgat ttcagatttg ctcaatctat caagaattga
     6121 taatcatgtg acacagctgt ctgttgaaat gaccaacttt acagccttta tgacctctat
     6181 cttaaaccgc tttgatttgg tgaaaaatca gcacaccagt acaggaaaat cctatgaaat
     6241 tgtcagagat taccctatca cctctatttg gctagaaatt gataacgata aaatgacgca
     6301 ggtcattgaa aatattttaa acaatgccat caaatattca cctgatggtg ggaaaattat
     6361 cgtaaacatg aaaacaacag atacccagct aatcatttcg atttctgatg agggattggg
     6421 cataccaaag aaggacctgc ctttgatttt tgaccgtttt taccgagtgg ataaggctag
     6481 aagtcgggcg cagggggggg ccggcttagg gctggctatt gctaaagaaa ttattaagca
     6541 gcgccgcggc tttatctggg ctaagagtga ctatggcaag gggtcaacct ttaccattgt
     6601 gttaccttac gaaaaggatg ctgctatcta tgatgaatgg gaggatgata ttgattaatt
     6661 gatgagtgag gttggcttta aatatagtat tttagcatca ggatcgacag gtaactgctt
     6721 ttacttggaa acgcccaaga agcgactgtt gattgatgca ggactgactg gaaagaaaat
     6781 caccagtctt cttgctgaga ttgacagaag gcctgaggat ttggatgcta tcttgattac
     6841 ccacgagcat tccgaccata tcaagggtgt tggaatcatg gctcgaaaat ataacctaga
     6901 tgtctatgcc aatgaaaaga cttggcagat gattgatgag cgtcatatga ttggcaacct
     6961 agacgtcgca caaaagcatg tctttgaaag aggtaagacc atgacctttg gagacattga
     7021 cattgagagc tttggtgtta gtcatgacgc tgtagaccca cagttttacc gcattatgaa
     7081 ggataacaag tcctttgtca tgctgacgga tacaggatat gtgagcgacc gcttggctgg
     7141 gatcattgaa aatgctgacg gctacttgat tgagtcaaat cacgatgtgg agatattgcg
     7201 agccggctct tatccttgga gcctcaagca gcgaatctta tctgacctag ggcatttatc
     7261 caatgaagat ggtgctggcg ctatgattcg aagcttgggc aataaaacaa agaaaatcta
     7321 cctcggtcac ctaagccagg agaacaatat caaagaatta gcacacatga caatggtcaa
     7381 tcagctagca atggcagatt taggtgttgg aacagatttt actgttcatg acacctcacc
     7441 agataccgcc tgtcccttga cagacatcta gccttatgac ttcacccctg cttgt
//
LOCUS       DARYNN010000079         7338 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.079, whole genome shotgun sequence.
ACCESSION   DARYNN010000079 DARYNN010000000
VERSION     DARYNN010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7338)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7338)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7338
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.079"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            <1..351
                     /locus_tag="TVB59_001882"
     CDS             <1..351
                     /locus_tag="TVB59_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1010736.1"
                     /translation="RGEQGPKGDRGEQGPKGDRGEQGPKGERGEQGPKGDRGEQGPKK
                     EPEKDTKPSVPKAPDNMAAPKAPEKKNPKAPAPKSAPKASLPSTGDTSQSFVAAALGF
                     IASAGLLVFKRKKN"
     gene            877..1767
                     /gene="rapZ"
                     /locus_tag="TVB59_001883"
     CDS             877..1767
                     /gene="rapZ"
                     /locus_tag="TVB59_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEL1010737.1"
                     /translation="MSDKQINLVIVTGMSGAGKTVAIQSFEDLGYFTVDNMPPALVPK
                     FLELLERTNETQKVALVVDMRSRRFFKEINSILDHIELNANLKLRILFLDATDSELVS
                     RYKETRRSHPLAADGRVLDGIRRERELLVPLKSMSQHVVNTTDLTPRQLRKVISDQFS
                     SESDQASFRIEVMSFGFKYGLPLDADLVFDVRFLPNPYYQVALREQTGLDQAVFDYVM
                     THQESEAFYNHLLGLIVPILPAYQKEGKSVLTIAIGCTGGQHRSVAFAHRLAQDLTAD
                     WPLHESHRDINRRKETVNRS"
     gene            1764..2741
                     /locus_tag="TVB59_001884"
     CDS             1764..2741
                     /locus_tag="TVB59_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEL1010738.1"
                     /translation="MRNPKITVIGGGTGIPVILKSLRKEAVDITAVVTVADDGGSSGK
                     LRNAMQLTPPGDLRNVLLAMSDMPKFYERVFQYRFNEADGALAGHPLGNLIIAGISEM
                     QGSTYNAIQILTKFFHITGKIFPSSEQPLTLHAVFKDGHEVSGESSIASYQGMIDHVY
                     VTNTYNDDLPKASRKVVEAILQSDMIVLGPGSLFTSILPNLVIPEIKEALRVTKAEVV
                     YICNIMTQYGETEQFSDADHVAVLNQHLGRDLIDTVLVNVEQVPKSYMNSNQFDEYLV
                     QVEHDFAGLCKTAKRIISSNFLRLENGGAFHDGHLVVEELMNLVRITKL"
     gene            2738..3649
                     /gene="whiA"
                     /locus_tag="TVB59_001885"
     CDS             2738..3649
                     /gene="whiA"
                     /locus_tag="TVB59_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEL1010739.1"
                     /translation="MSFTTTVKEELIHLSASDQTELSAIIKLAGSLGLANQSLNLSIT
                     TENAKIARYIYALIEDTYHIIPEIRYHQKTNLKKNRVYTVYLDKQVDKLLADLKLADS
                     FFGIETGIEQQVMSDDDAGRAYLKGAFLAAGTVRDPESGKYQLEIYSVYLDHAQDLAQ
                     LMHKFMLDAKVIERKNGAVTYLQKAEDIMDFLIIIGAMSCKEEFEAVKLLREARNDIN
                     RANNAETANIAKTITASMRTINNIIKIMDTIGLDSLPVELQQIAQMRVANPDYSLQQI
                     ADSLDFAITKSGVNHRLRKINKLAEDL"
     gene            4009..5406
                     /locus_tag="TVB59_001886"
     CDS             4009..5406
                     /locus_tag="TVB59_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C69 family dipeptidase"
                     /protein_id="HEL1010740.1"
                     /translation="MSCTTILVGKKATYDGSTIVARTEDSQNGEFTPKKMTVVRPKDQ
                     PRHYQSVLSSFSMELPDQPMAYTSVPDALGKDGIWGEAGVNTLNVAMSATETITSNAR
                     VLGADPLVSSGIGEEDMLTLVLPYIRSAREGVLRLGAILEAYGTYEANGVAFSDEHEI
                     WWLETIGGHHWIARRVPDDAYVTNPNQFGLDHFEFNNPEEYLCSKDLKDFIAKYHLDL
                     TYSNEHFNPRYAFGSQRDKDRHYNTPRAWIMQQYFNPEFLQDPRSFELPWCQRPDRKV
                     TIEDVKYVLSNHYQDTPYDPYGPEGTPTSRKSFRPIGINRTSQTAILHIRPNKPKEIA
                     AIQWMAYGSMPFNTIVPLFTQVKTIPDYFANTVENVSTDNFYWTNRLIAALADPHFKH
                     HEADLEDYLEKTMAKGHAMLHAVEAALVKGQPVDLEEANQGMSDDIQADTQALLNKIL
                     FDASNLMTNRFSLSD"
     gene            5646..7196
                     /locus_tag="TVB59_001887"
     CDS             5646..7196
                     /locus_tag="TVB59_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HEL1010741.1"
                     /translation="MKKKYLLMMSVLGVFFAGQISQAKQVLADSKVKIVTTFYPVYEF
                     TKGVVGGEGNVSMLMKAGTEPHDFEPSTKDIKKIQDADAFVYMDDNMETWVPDMKKSL
                     TSKKVTVIKGTGDMLLVAGSGHSHEHDHDDADKKHDHDHDEEGHSHAFDPHVWLSPYR
                     SITVVETIRDGLSKAYPDKADHFKSNAAAYIEKLKELDKEYSDAFSAAKQKSFVTQHA
                     AFGYMALDYGLNQISINGVTPDTEPSAKRIAELSKYVKKYDINYIYFEENASSKVAKT
                     LAKEAGVKSAVLSPLEGLTEKDMKAGKDYFTVMRENLKTLRLTTDVEGKEILPEEDTT
                     KTVYNGYFKDKQVKDRKLSDWSGNWQSVYPFLQDGTLDQVWDYKAKKSKGKMTAAEYK
                     DYYTTGYQTDVSHIKINGKKNTMTFVRNGENKTFTYKYVGKKILTYPKGNRGVRFMFE
                     AKEPDAGEFKYVQFSDHAIAPGKAEHFHLYWGGDSQEKLHKELEHWPTYYDADLSGRA
                     VAQEINAH"
BASE COUNT         2163 a         1489 c         1683 g         2003 t
ORIGIN      
        1 cgtggcgagc aaggaccaaa aggtgatcgt ggcgaacaag gaccaaaggg tgatcgtggc
       61 gagcaaggac caaaaggtga acgcggtgag caaggaccaa aaggcgatcg tggcgagcaa
      121 ggtccaaaga aggagccaga aaaagacacc aagccatcag tgccaaaggc accagataat
      181 atggctgcac caaaggctcc ggagaagaag aaccctaaag caccggctcc taagtcagct
      241 ccaaaggcat cattgccatc aacaggagac actagccaat catttgttgc agcagccctt
      301 ggctttatcg ctagcgcggg cttgctagtc ttcaaaagaa agaaaaacta agctagctaa
      361 agactgtaaa caagcctcaa ctgttacagc aagcctcttt gacatcttgc agataagagg
      421 atttcttagc gaatgaagtg tgtctaaagt cagatactct gctggactag cagtagctga
      481 tctccctgaa aatcagttat gctaaagcat tgagccttag ttgcaaggct taggtgtgac
      541 cttccaaagg aagctgcttt tgcctgtatc actttaggaa gatatctaaa agagacactt
      601 ttttcacgct gaagctaagc tagcttttcc tatgacaaat atcctataac aataaactcc
      661 aaacaaaaga gaggtcaaat ggtacctctc ttttacttag ctttaggatt gatagattct
      721 aaaggcttcc ttgtttcttg atcaagaagt ccttactgat agagtctgtc ttagccgggc
      781 ttatatggta taatacctaa tggagataag aaaagtcctt aacaaataga gtttcatcta
      841 ttgttacagg agcaaccaag tgaaaggaga tgctacatgt cagataaaca aatcaatttg
      901 gttattgtta caggaatgag tggcgccggc aaaacagttg ccattcaatc atttgaggat
      961 ttggggtatt ttactgttga taacatgcca ccagctttag tgcctaaatt tttagagctg
     1021 cttgagagga ccaatgaaac ccaaaaggtt gctctggtag tggatatgcg cagcagacgc
     1081 tttttcaagg agattaactc tatcttagat catattgagc taaatgccaa cctcaagcta
     1141 cggatcctct ttcttgatgc gactgatagt gagctagtgt cacgctataa ggaaactaga
     1201 agaagtcacc ctctggctgc tgatggtcgg gtgcttgatg ggattcgacg agaaagagag
     1261 ctgttagtcc cgcttaagag catgagtcag catgtggtca ataccaccga tctaacccca
     1321 agacagctgc gtaaggtgat ttcggatcag ttttcaagcg agtcagacca agcctcattt
     1381 agaattgagg tgatgagctt tggctttaaa tatggcctcc ccttagatgc ggaccttgtc
     1441 tttgatgtgc gctttttgcc taatccttat tatcaggtgg cgctaagaga gcagacaggg
     1501 cttgatcagg ctgtttttga ttatgtgatg actcatcaag agtcagaggc cttttataat
     1561 catttgttag gcttgattgt tcctattttg cctgcttatc aaaaggaagg caaatcagtg
     1621 ctaaccattg ctattggctg tacaggtggt cagcatagaa gtgtcgcctt tgcccatcgc
     1681 ttggcccaag acttgacagc agactggccg ctgcatgaga gtcatcggga catcaatcgt
     1741 cgtaaggaaa cggtaaatcg ctcatgagaa atcctaaaat aacggtgata ggaggaggaa
     1801 caggtattcc tgttatccta aaaagccttc gcaaggaggc ggttgacatt actgcggtgg
     1861 tcactgttgc tgatgatggt gggtcatctg gtaagctgcg caatgccatg cagcttaccc
     1921 cgccaggtga tttgcgcaac gtcttgttgg ccatgagtga catgcctaag ttttatgagc
     1981 gtgtgtttca gtatcgtttt aatgaggcag atggtgctct agctggtcat cctctaggca
     2041 atttaattat cgcaggtatt tctgagatgc agggatccac ctataacgct attcagattt
     2101 tgacgaaatt tttccatatc accggcaaga tttttccctc aagcgagcag cccttgacac
     2161 tgcatgctgt ctttaaggac ggtcatgagg tgtcaggaga aagctctatt gccagctacc
     2221 aaggcatgat tgaccatgtc tatgtgacca atacctacaa tgatgacctg ccaaaggcca
     2281 gtcgtaaggt ggttgaggcc attctccaaa gtgatatgat tgtgcttggt cctggttcct
     2341 tgtttacctc tattttgccc aatcttgtaa ttccagagat caaagaagcc ctgagagtaa
     2401 ccaaggcaga ggtggtttat atttgtaaca ttatgaccca gtacggtgag acagagcaat
     2461 tttccgatgc ggatcatgtt gcggttttaa atcagcatct gggcagggac ttaattgaca
     2521 ctgttttggt taatgttgag caggtgccaa aaagctatat gaattccaac caatttgacg
     2581 aatatctggt ccaagtagag catgactttg caggtctgtg taagaccgca aagcgtatca
     2641 tctcgtctaa ttttctgcgt ttggagaatg gcggagcctt tcatgacggg cacttggttg
     2701 tagaagaatt aatgaaccta gttaggataa ccaagctatg agttttacga caactgttaa
     2761 agaagaattg attcatttat ctgcttctga tcaaacagaa ttatcagcaa tcatcaagct
     2821 ggctggtagc ctaggcttgg ctaatcagag cttgaatttg tctatcacaa ctgaaaacgc
     2881 taagattgct cgctacatct atgcgcttat cgaagacacc tatcatatca ttccagaaat
     2941 caggtaccat caaaagacca acttgaaaaa aaatcgtgtc tatacggttt atttggataa
     3001 gcaggtggat aagctcttag cagatttaaa gctggcagat tctttttttg gcattgagac
     3061 aggtattgag cagcaggtca tgtcagatga tgatgctggt cgggcctatc tcaagggtgc
     3121 ttttttagcg gcagggactg taagggatcc agaatccggc aagtatcagc tagagatcta
     3181 ctctgtctat ctagaccatg ctcaggattt ggcccagctc atgcacaaat tcatgctaga
     3241 tgccaaggtt atcgagagaa aaaatggtgc agtaacctat ttgcaaaagg ctgaggacat
     3301 catggatttt ctcattatta ttggtgccat gtcgtgtaag gaggagtttg aggctgttaa
     3361 gcttttgcgt gaggcgagaa atgacatcaa tcgggccaat aatgcagaga ctgctaatat
     3421 tgctaaaacc atcaccgcca gcatgagaac cattaataat attatcaaaa tcatggatac
     3481 gattggctta gacagcctgc cagttgagct gcagcagatt gcccagatga gagtagccaa
     3541 cccagactat tctcttcaac aaatcgcaga ttcgcttgac tttgccatca ctaagagtgg
     3601 ggtcaaccat cgcctgcgaa aaatcaataa gctggcagag gatttataaa gacagcttag
     3661 cctttttcag gctgataaaa aagggggtaa ggtgatacga acaagccgcc ttttaaggca
     3721 tgccttgttg agctttctct aggctgttga tggagtgatc tcaaggcgct tttgttactg
     3781 tcattccaac aggctatctg attttgggat gacttcttac taataagctt ttctaatggc
     3841 tggctgacaa cgattagcga tatagttaag gcttatcgtg attcaacaag aggctttagt
     3901 ctcttttttg cttgtcagaa ttattttttt aggcttttct tacaaatgag aggacaatgt
     3961 gacaatctgt ggtatgatat tagtaatgaa tacaaaggag aacaaatcat gtcatgcaca
     4021 actattcttg tcggtaaaaa agcgacctat gatggatcaa caatcgttgc tcgtacagag
     4081 gattcacaaa atggggaatt tacccctaaa aaaatgacag ttgttagacc aaaagaccaa
     4141 cctagacact atcaatctgt cttgtctagc tttagcatgg agctgccgga tcagccgatg
     4201 gcttatacct cggtgcctga tgccctagga aaggacggta tctggggaga agcaggtgtc
     4261 aataccctca atgttgctat gtcagcaact gagaccatta cttcaaatgc tcgcgttctt
     4321 ggagcagatc ctcttgtttc ctctggtatt ggagaagagg acatgctgac cttggtgctt
     4381 ccttatattc ggtctgcaag agagggtgtt cttcgtttgg gagctatcct agaagcatac
     4441 ggtacctatg aggctaacgg tgttgccttt tctgatgagc atgagatttg gtggctggaa
     4501 acaataggtg gtcatcattg gattgcaagg cgcgttcctg atgatgctta tgtcactaat
     4561 cccaaccagt ttggccttga tcactttgaa tttaacaatc cagaggaata cctgtgttcc
     4621 aaggatttaa aggactttat tgccaaatat catctagatt tgacctatag caacgagcat
     4681 tttaaccctc gctacgcctt tggtagccaa agagataagg atcgccatta caatacacca
     4741 cgcgcttgga ttatgcagca atactttaat ccggagtttc tgcaggatcc gcgcagcttt
     4801 gaacttcctt ggtgccaaag acctgatcgc aaggtgacca ttgaagacgt taagtacgtg
     4861 cttagcaatc attatcagga caccccttat gatccttacg gcccagaggg aacgccgact
     4921 agtcgaaaat cctttaggcc gattggtatt aaccgtacga gtcaaactgc tattttacat
     4981 atccgtccca acaagcctaa ggaaattgct gccattcagt ggatggccta tggttcgatg
     5041 ccctttaata caatcgttcc gctattcacc caggtcaaga ccattccaga ttattttgca
     5101 aacactgttg aaaatgtttc cacagacaat ttctattgga ccaatcgctt gattgcagcc
     5161 ctggctgatc ctcacttcaa gcaccatgaa gcagatttgg aggactatct cgaaaaaaca
     5221 atggccaagg gtcatgccat gctgcatgct gttgaagcag cgctagtaaa aggtcagccg
     5281 gttgacctag aagaggccaa ccaaggcatg agtgatgaca ttcaggcaga tacacaggct
     5341 ctgctcaata agatcctctt tgatgctagc aatctcatga ccaaccgctt tagcctaagc
     5401 gactaagtaa tctcaatagt caaacgagct catatcatta tagatatggg ctcttagctt
     5461 gaaaaggata gtagagcggt cttatagtca gactaattaa tggtaacgat gagtccagtt
     5521 aaggtaaaaa aagagcactt agctaatgca aaaaaagtaa aaaacttgca aaagaatgat
     5581 attgtgttat acttaaccag taaatattaa gagctatttg cgatatgata tatagaggag
     5641 gaatcatgaa aaagaagtat cttttaatga tgagtgtgct cggtgtcttt tttgcgggac
     5701 agatcagtca agcaaaacag gtcctagcag atagtaaggt caaaattgtt accaccttct
     5761 atcctgttta tgaatttacc aaaggcgttg tcggaggtga gggaaatgtg tctatgctga
     5821 tgaaagcagg aacagagcct catgattttg agccgtcaac aaaggacatc aaaaagatcc
     5881 aagatgccga tgcctttgtt tatatggacg ataatatgga aacttgggtc cctgatatga
     5941 agaaatcact gacttctaag aaggttacgg tgattaaggg aacaggagat atgctattgg
     6001 tagctggctc tggtcacagc cacgagcatg accatgacga tgccgataaa aagcatgatc
     6061 atgaccacga cgaggaagga cacagccatg cttttgaccc gcacgtatgg ttgtcacctt
     6121 atcgcagcat caccgttgtc gaaacaattc gtgatggtct atctaaggcc tatcctgaca
     6181 aggctgacca cttcaaatct aatgccgctg cttatattga aaagctcaag gaattagata
     6241 aggagtatag tgacgctttt tcagctgcca agcaaaagag ctttgtgact cagcacgcag
     6301 cctttggtta tatggcgctt gattatggct tgaaccaaat ctcaatcaat ggtgtcacac
     6361 cagatacgga gccttcagct aagcgcattg cagagctatc aaaatacgtc aaaaaatatg
     6421 acattaacta catttatttt gaagaaaatg cttcaagcaa ggttgccaaa accctagcca
     6481 aggaggctgg tgtcaaatca gctgtcctta gtccgcttga aggcctaact gaaaaggaca
     6541 tgaaggccgg caaggattac tttaccgtta tgcgtgaaaa cctcaaaacc ctacgcttaa
     6601 caactgatgt agaaggaaaa gaaattcttc cagaagagga taccactaaa actgtttata
     6661 atggctactt taaggataag caggtcaaag accgcaaatt gtctgattgg tctggtaact
     6721 ggcagtctgt ttacccattc cttcaagacg gtacattaga tcaggtatgg gactataagg
     6781 ctaaaaaatc taaaggaaaa atgaccgcag ctgaatacaa ggattattac accactggct
     6841 atcagacaga tgtcagtcat atcaagatta atggtaagaa aaataccatg acctttgttc
     6901 gtaatggtga aaataaaacc tttacttata agtacgtcgg taaaaagatt ttgacctatc
     6961 caaagggcaa tcgtggcgtg cgcttcatgt ttgaagctaa ggagccagac gctggtgaat
     7021 ttaaatatgt tcagttcagt gaccatgcta tcgcaccagg taaggcggag catttccacc
     7081 tatactgggg tggtgacagc caagaaaagc ttcacaaaga gctagagcat tggccaactt
     7141 actatgatgc ggacctatca ggtcgtgccg ttgcccaaga aatcaatgct cattaaccac
     7201 tcaaaagact aggcagttca atcggcctag ttttttcttg tcttagttgc tgtataggac
     7261 ctaaatgctg atagctggtc ttaagattta tttttaattt ttctaactat atttaggttg
     7321 tatttgtttg ttaatacc
//
LOCUS       DARYNN010000080         6885 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.080, whole genome shotgun sequence.
ACCESSION   DARYNN010000080 DARYNN010000000
VERSION     DARYNN010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6885)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6885)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6885
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.080"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(25..486)
                     /locus_tag="TVB59_001888"
     CDS             complement(25..486)
                     /locus_tag="TVB59_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComE"
                     /protein_id="HEL1010742.1"
                     /translation="MTDRLSWQDYFMANAELISKRSTCDRAFVGAVLVKDNRIIATGY
                     NGGVSATDNCNEAGHYMEEGHCIRTVHAEMNALIQCAKEGISTAGTEIYVTHFPCINC
                     TKALLQAGICKITYKSHYRPHPFAIELMDKKGVAYVQHDVPQIILGGAVEP"
     gene            complement(530..1606)
                     /locus_tag="TVB59_001889"
     CDS             complement(530..1606)
                     /locus_tag="TVB59_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEL1010743.1"
                     /translation="MSSFLAQRLSNCQALLEKKGLEAILITNLTNIYYLTGFSGTSAT
                     VFISPKRRVFITDSRYTLIAKASIEGFDIIESRTPLAEIAAILQADKLSSLAFEDQVS
                     FSFSQSLQAAFSEVTLLPQSGFIEALRLIKDASEIDIIAKACSISDKAFCDVLDFIKP
                     GQTSELEVANFLDFRMRQYGASGISFDTIAASGYRSAMPHGRATDKIIQQGETLTLDF
                     GCYYQHYVSDMTRTIHIGQVTDQEREIYELVLAANQALIAKAGAGMTYREFDAIPRQL
                     ITEAGYGSHFTHGIGHGIGLDIHEDPFFAKTDQRLLAGMVVTDEPGIYLDGKYGVRIE
                     DDLVITETGCQVLTKAPKELIVLT"
     gene            complement(1897..4719)
                     /gene="uvrA"
                     /locus_tag="TVB59_001890"
     CDS             complement(1897..4719)
                     /gene="uvrA"
                     /locus_tag="TVB59_001890"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEL1010744.1"
                     /translation="MQDKLIIRGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGNMEKPDVDSIDGLSPAISIDQKTTSKNPRSTVGTV
                     TEINDYLRLLYARVGTPYCINGHGAITASSVEQIVEQVLELPERTRMQILAPLVRRKK
                     GQHKTVFEKIQKDGYVRVRVDGEIFDVSEVPALSKSKMHNIEVVIDRLVNKDGIRSRL
                     FDSIEAALRLGDGYLMIDTMDGNELLFSEYYSCPVCGFTVPELEPRLFSFNAPFGSCP
                     TCDGLGIKLEVDLDLVVPDPSKTLREGALAPWNPISSNYYPTMLEQAMQSFGVDMDKP
                     FEQLSEQEKELILYGSGDQEFHFHYVNDFGGERSIDIPFEGVVTNINRRYHETNSDYT
                     RNVMRGYMNELTCASCHGYRLNDQALCVRVGGEYGLTIGQVSELSIADHLQLLDRLEL
                     SDNESTIAKPIIKEIHDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYVLDEPSIGLHQRDNDRLIDSLKKMRDLGNTLIVVEHDEDTMMQADWLIDVGPGA
                     GDFGGQIVASGTPQQVARHKRSITGQYLSGRKSIPVPLERRAGNGRYIDIKGAAQNNL
                     QNLDVRFPLEKFIAVTGVSGSGKSTLVNSILKKAVAQRLNRNSEKPGKHRSITGIDHL
                     ERLIDIDQSPIGRTPRSNPATYTGVFDDIRELFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVPCDVCHGRRYNSETLEVHYKGKNIAEILDMTVDDALV
                     FFSAIPKIARKIQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSLYIL
                     DEPTTGLHTDDIARLLKVLERFVDDGNTVLVIEHNLDVIKSADHIIDLGPEGGVGGGQ
                     LVATGTPEEVAAVEESYTGQYLKLKL"
     gene            4915..5859
                     /locus_tag="TVB59_001891"
     CDS             4915..5859
                     /locus_tag="TVB59_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEL1010745.1"
                     /translation="MKQMFLSSAIEFKEIETFEPGAWIKLVNPSQEESIAIADQFNID
                     ISDLRAPLDVEETSRIAVEDDYTLIIVDVPVYEERNNKSYYVTMPLGIIVTESAVITT
                     CLHDMTLFDQFHKRKVKNFYTFMKTRFVFQILYRNAELFLTALRTIDRQSERLEAQLE
                     AATRNEELIDMMELEKSIVYLKASLKFNERIVKKLSSSTSSLKKYIEDEDLLEDTLIE
                     TQQAIEMAGIYENVLNAMTETTASIINNNQNTIMKTLALMTMALDIPTVIFSAYGMNF
                     QDNWLPLNGLSHAFWYIVLLATLLSSFVVIYFIRKKWF"
     gene            6118..6768
                     /locus_tag="TVB59_001892"
     CDS             6118..6768
                     /locus_tag="TVB59_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013643410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 family protein"
                     /protein_id="HEL1010746.1"
                     /translation="MDLQQLTKKNQEFIHIATNQLIKDGKTDDDIKALLEEVIPTILE
                     NQKKGITARSLYGAPTAWAASFSKEANQKEATPKNTNPWLMWLDTSLLFIGIVGLLNS
                     IMTFFNTNTTVTGLVSLLALGFGGGASMYATYYFVYRHMGKDKSLRPSWFKVIGALTL
                     AMLAWITLYSATAFLPKALNPQLPPVALLITGALAIGLRYLLQRKYNIQNTMAPQR"
BASE COUNT         1998 a         1792 c         1334 g         1761 t
ORIGIN      
        1 ttatgaccat tatcagcctt cggcctaagg ctcaacagcg ccacccaaga taatctgagg
       61 cacatcatgc tgaacataag caaccccttt tttatccatt agctcaatgg caaaagggtg
      121 gggacgataa tgggatttat aggtgatctt gcaaataccg gcctgaagga gggccttagt
      181 gcaattgata caaggaaagt gcgtgacata aatctctgtt ccagcagttg aaatgccctc
      241 cttagcacat tgaatcaaag cattcatctc tgcatgaaca gttctgatac aatgcccttc
      301 ttccatataa tgaccggctt cattacagtt atcagtcgcc gacacgccac cgttatagcc
      361 tgtcgcaata atgcgattgt ccttgaccaa gactgcaccg acaaatgctc gatcgcaggt
      421 tgatcgctta gatatcagct ctgcatttgc cataaaataa tcttgccatg atagcctatc
      481 tgtcatgctt tgtctcctaa tcccttctaa ctcacagcag ctaacaagcc tacgttaaaa
      541 caatcaattc ctttggtgcc ttggttaaga cctgacagcc tgtttctgtg atgacaagat
      601 cgtcctcaat acgcacaccg tatttgccgt ctaaatagat acccggttca tctgtcacca
      661 ccataccagc tagaagcctt tgatctgtct tagcaaaaaa tggatcctca tgaatatcaa
      721 gtccgatccc atgaccaatg ccatgtgtaa agtgactgcc atatcctgcc tcagtaatga
      781 gctgacgagg aatagcatca aactcacgat aggtcatgcc tgcaccagcc tttgcaatca
      841 aagcctgatt agctgcaaga accagctcat aaatctcacg ctcctggtct gtcacctgtc
      901 cgatatgaat agtccttgtc atatcactca cataatgctg ataataacag ccaaagtcaa
      961 gcgtcaaagt ctctccctgc tgaatgattt tatctgtagc acgaccatga ggcatggcag
     1021 aacgatagcc tgaggctgca atggtgtcaa aggaaatgcc tgaggcaccg tattgacgca
     1081 tgcgaaaatc caagaaatta gccacttcaa gctcacttgt ctgccccggc ttaataaagt
     1141 ccaagacatc acagaaggcc ttgtctgaaa tcgagcaggc tttagcaata atgtcaatct
     1201 cagaagcgtc cttaatcaga cgaagcgctt caataaagcc tgattgcggc agcaaagtca
     1261 cctctgaaaa ggctgcctga aggctttgag aaaaggaaaa ggacacctga tcctcaaagg
     1321 ctagactgct aagcttgtcc gcctgtagga ttgcagcaat ttcagccagc ggtgtgcggc
     1381 tctcaatgat atcaaagccc tcaatactag ccttagcaat taaggtataa cgcgaatctg
     1441 taataaaaac acgccgcttt ggactgataa agaccgtagc tgaggtccct gaaaagcctg
     1501 tcaggtaata aatattagtc agattagtaa ttaaaatagc ctccaagcct tttttttcca
     1561 gtaatgcttg gcaattgctt aagcgctgtg ctaaaaatga tgacatggta atctccttta
     1621 tcgacaaaac taccttaagt ttaccatgat ttcaacgctt ttaaaagcaa gacccattaa
     1681 agacagccaa caaaaaaagc atttctgaca gtggaccaaa aggctaatca gcttagccgc
     1741 cactaccaaa aatacccttt aaatatcacc cacgcccccc gcgaagagag ctactggcta
     1801 tctattattt aaattaaaat cacccctcat ttcaatccat gccctatcat cgttcatacg
     1861 aagatcactc tgtcaattga tgtcaggcct gcaactttac aatttcagct tcaggtactg
     1921 ccctgtgtag ctttcctcaa cagcggcaac ctcttcagga gtcccagttg caaccagttg
     1981 acctccacca acaccgcctt ctggaccaag gtcaataata tggtctgccg acttgatgac
     2041 atctaaattg tgctcaatca ctaaaacagt attaccatca tcaacaaagc gctctaaaac
     2101 cttcagtaat cgcgcaatgt catctgtatg cagccccgtc gttggctcat ctaaaatata
     2161 caagctttta ccagttgaac gcttgtgcaa ttcactagcc agcttcatgc gctgggcctc
     2221 gccacctgat agggttgtcg ctggctgccc tagagtaaca tagccaagcc caacgtcctt
     2281 aatggtctga attttacgag caatctttgg aatagctgag aaaaatacca gagcatcatc
     2341 taccgtcata tccaagattt cagcaatgtt tttgccctta taatggacct ccaacgtctc
     2401 tgaattatag cgtctgccat gacaaacatc acatggaacg taaacatctg gtaaaaaatg
     2461 catctcaatc ttgataatcc catctccaga gcaggcttca cagcggcctc ccttcacatt
     2521 aaaggagaag cgcccttttt tgtagccacg aatcttggct tcattagtct gggcaaagag
     2581 ctctcgaata tcatcaaaaa caccggtata ggtggcagga ttagagcgcg gtgtccgccc
     2641 aattgggctt tgatcaatat caatcaaccg ttccaaatgg tcaatgccag tgatagacct
     2701 atgcttgcct ggcttttcag agttacggtt tagcctttga gccactgctt ttttgagaat
     2761 gctattaacc agcgttgatt ttcctgagcc agagacccca gtcactgcaa taaatttctc
     2821 cagaggaaac ctcacatcaa gattctgcag attgttttgg gctgctccct tgatatcaat
     2881 atagcgacca ttgccagcac gtcgctccaa aggaacgggt attgatttgc gtccagacag
     2941 gtattgacca gtgatagacc ttttatgccg agcaacctgc tgaggcgttc cagaggcaac
     3001 aatctgcccg ccaaagtccc cagcaccagg tcccacatca atcagccaat ctgcctgcat
     3061 catggtatcc tcatcgtgct caaccacaat caaggtattt cccaagtcac gcattttttt
     3121 caagctatca atcaagcgat cgttatctcg ctggtgcaga ccaatagaag gctcgtccaa
     3181 aacgtaaagg acacctgaca gattagagcc aatttgcgtt gccaaacgga tacgctgact
     3241 ctctccacca gacaaggtgc ctgccgagcg agacaaggtc agataattca gaccgacatt
     3301 attcaaaaag gtcagccgat catgaatttc cttgataatt ggctttgcaa tggtgctttc
     3361 attgtctgac agctcaagcc gatctagcag ctgcagatgg tctgcaatag atagctctga
     3421 cacctgaccg atcgtcaagc catactcacc accaacacgc acacacaggg cttgatcatt
     3481 gaggcgatag ccatgacagc tcgcacaggt caattcgttc atatagcctc gcatgacatt
     3541 gcgggtatag tcactgttag tctcatggta gcgacggtta atatttgtca caaccccttc
     3601 aaagggaata tcaatgctgc gctcgccacc aaaatcattg acatagtgaa aatggaactc
     3661 ctgatcacct gagccataca ggatcagctc cttttcctgc tcgctcaatt gctcaaaagg
     3721 cttgtccata tcaacaccaa agctctgcat tgcctgctca agcatggttg ggtaataatt
     3781 tgacgagata ggattccaag gagcaagagc cccctctctc aaggtcttgc tgggatcagg
     3841 aacaactaga tccaaatcca cctccagctt gatccctaag ccatcacagg tagggcaaga
     3901 gccaaagggc gcgttaaatg aaaaaagacg aggctctagc tctggcactg taaaaccaca
     3961 taccggacag gaataatact ctgaaaacag caactcattg ccgtccatcg tatcaatcat
     4021 cagatagcca tctcccaagc gaagcgcagc ctctatcgaa tcaaaaagac gactgcggat
     4081 cccgtcctta ttgaccaagc gatcaatgac gacctctata ttgtgcattt tgcttttgga
     4141 taatgctggt acctctgaca catcaaaaat ctctccatca acacgcacgc gcacataacc
     4201 gtccttttga attttctcaa acactgtctt gtgctgaccc tttttacgac ggacaagagg
     4261 cgccaaaatc tgcatacgcg tccgctcagg caactctagc acctgctcaa caatctgctc
     4321 caccgaggaa gccgtaatag ccccatgccc attgatacaa tagggagtcc ccacacgcgc
     4381 ataaagaagc ctgaggtaat cattgatttc tgtcaccgta ccaacggttg atctaggatt
     4441 cttgctggtt gttttttggt caatagaaat agcaggacta agcccgtcta tagaatccac
     4501 atcaggcttt tccatgttgc ctaaaaattg cctagcatag gctgacaggc tctccacata
     4561 gcgacgttgt ccctcagcat agatggtatc aaaggcaagg ctagattttc cagatcctga
     4621 taagccggtc accacaacga gcttatcacg tggaatctcc acatcaatat tttttaaatt
     4681 gtgggcacgc gccccacgaa taatcaattt atcttgcatg ctcttgtgcc cccaggcacc
     4741 ctcctcatcg agatttattc cattataaca aaaatttcta ataatcagtt gccccaaaca
     4801 ccatgaattt gtagtataat agacaggtat tgagtgtttt tcaaaaaggc ttcgtctacc
     4861 tgatgacaag aagctcactt caatactgac taatcacaaa aaggagggct tgtcatgaaa
     4921 caaatgtttc tttcatcggc aattgaattc aaagaaatcg aaacattcga gccaggtgct
     4981 tggatcaaat tggtcaaccc ctcccaggaa gagtctatcg ccattgccga tcaatttaac
     5041 attgatattt ctgacctgcg tgcccctttg gacgttgaag aaacctcacg tattgctgtt
     5101 gaggacgact acaccttgat tatcgtcgac gttccggtct atgaggagcg caacaacaaa
     5161 agctactatg tgaccatgcc tttgggaatt atcgtcactg aaagcgcggt aatcaccacc
     5221 tgcctgcatg acatgacact ttttgatcag tttcataagc gtaaggttaa aaacttttac
     5281 acctttatga agacacgttt tgtctttcaa attctctacc gcaatgccga gcttttccta
     5341 accgcactaa gaacaattga ccgacaaagc gaacgcttgg aggctcagct tgaggcagca
     5401 acccgaaacg aagaattaat cgacatgatg gagcttgaaa aatccatcgt ctacctaaag
     5461 gcctccctaa agttcaacga gcgcattgtc aaaaaattat ccagctcaac cagctcactc
     5521 aaaaaatata ttgaggacga ggacctgctt gaggatacac tgattgagac ccaacaggct
     5581 attgagatgg ctggcattta tgaaaatgtc ttaaatgcca tgaccgaaac aaccgcctca
     5641 atcattaaca acaatcagaa caccatcatg aaaacattgg ctctgatgac gatggctcta
     5701 gatattccga cagtgatctt ctcagcctac ggcatgaact ttcaggataa ttggctgccg
     5761 ctcaatggcc ttagccatgc cttctggtat attgtcctgc tggcaaccct gctcagcagc
     5821 tttgttgtta tttattttat tagaaaaaaa tggttttaat aaccccattt ccaactgaaa
     5881 aagctactcc tgagctctac ctgtagacag ctcatcagct aaagcaggca ctactactgc
     5941 taaagcaaac aatcgtccca gcaagtaacg gtagctacta ctgcttgatc gtatgatcaa
     6001 gcgcaacata tcagctgcca tactagctgg caaagcaagc cagcaaggcg cccttgaggc
     6061 attatcccag gctagccctg cttacaatca tcacatcata taggagaatc ccctgtcatg
     6121 gacttacaac agcttaccaa aaaaaatcaa gaatttattc atatcgccac caatcagctc
     6181 atcaaagatg gcaaaactga tgacgacatc aaggcacttc ttgaggaggt cattccgacc
     6241 atcttagaga accagaaaaa aggcatcact gcaagaagcc tatacggggc tccaactgcc
     6301 tgggcagctt cctttagtaa agaagcaaat caaaaagaag ccacacccaa aaacaccaat
     6361 ccatggctga tgtggcttga tacctcgctt ctatttatcg gtattgttgg ccttttaaac
     6421 agtatcatga ccttctttaa taccaacact accgttaccg ggcttgtgtc cttgcttgct
     6481 cttggctttg gagggggtgc ttccatgtac gccacctact attttgttta tcgccatatg
     6541 ggcaaggaca agagccttcg tccaagctgg tttaaggtta ttggtgctct gacacttgca
     6601 atgctggcct ggataaccct ctattctgct acagcctttt taccaaaggc gctcaaccca
     6661 caattacctc ctgtagcact tctcattacc ggtgccttag ctatcggact gcgttacctc
     6721 ttgcagcgca aatacaatat ccaaaacact atggcaccgc agcgctagca gcagctccac
     6781 tgcctgagga agcacttccc tattctctct tgagggcagt tagccttttc ataccatatt
     6841 gctggcaaca ccagacactg atctacaatc gacactcctc aatcc
//
LOCUS       DARYNN010000081         6399 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.081, whole genome shotgun sequence.
ACCESSION   DARYNN010000081 DARYNN010000000
VERSION     DARYNN010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6399)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6399)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6399
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.081"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(200..580)
                     /locus_tag="TVB59_001893"
     CDS             complement(200..580)
                     /locus_tag="TVB59_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HEL1010747.1"
                     /translation="MIKVFETRVTAIGSEAADMISAANMLILFDQGAPADLADFCYTI
                     DNKQVSGSISAGGQLVIDQMAYDITAVGAVVEKNLAQLGHITISFDGSTASSLPGTLH
                     VKGKGLPQVRQGSLVQIFAWLRCS"
     gene            complement(614..1606)
                     /locus_tag="TVB59_001894"
     CDS             complement(614..1606)
                     /locus_tag="TVB59_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002284531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HEL1010748.1"
                     /translation="MTYHSITVVKGSGGYGGPLTITPTEAKHKFIYITGGGKKPDIVD
                     KIAALTGMEAVNGFVTSIPDDEIALAIVDCGGTLRCGIYPKKGIPTINIVATGKSGPL
                     AQYITEDIYVSAVGLEQITASDAQAHVASAKESSVPKASSYDTSKKITEQRAESSFVA
                     RIGMGAGKVVAIFNQAAREAIQTLINTILPFMAFVSLLIGFIQGSGVGNWLAKLMVPL
                     AGNIWGLIIIGFICSLPFLSPLLGPGAVISQIIGTLIGVEIGKGTIPPQMALPALFAI
                     NTQNGCDFIPVALGLSEANAETVEVGVPSVLYSRFLNGVPRVVVAWIASIGLYQ"
     gene            complement(1622..2167)
                     /gene="srlA"
                     /locus_tag="TVB59_001895"
     CDS             complement(1622..2167)
                     /gene="srlA"
                     /locus_tag="TVB59_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677306.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HEL1010749.1"
                     /translation="MEMITRFAEGFMKLFQLGGETFVSWMTGIVPVVLMLLVAMNALI
                     GILGDQRVNQLAKISAKNPISRYMVLPFISAFMLGNPMAISMGRFMPEYYKPSYVAAQ
                     MQFCHTSNGVFPHINPGELFVWLGIASGIKTLGLSQMDLAIRYLLVGLIMNFVGGWVT
                     DFTTAYVAKQQGVTLSKMIEL"
     gene            complement(2303..2764)
                     /locus_tag="TVB59_001896"
     CDS             complement(2303..2764)
                     /locus_tag="TVB59_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HEL1010750.1"
                     /translation="MSFMVIFGLFVIVAYLFQLLLGLRQLKHFNAVYASLRRQGRVAI
                     GRRAGKIRAGTIVMFALDQSGKVLDARQMQGVTVAARFKPMPAYIGQDIHYFDRYNPL
                     IRRENKLLRLAIEDAREVFLRVEAGVYEDAPKYASAFDWTLQAKQLLARFK"
     gene            complement(2764..4536)
                     /locus_tag="TVB59_001897"
     CDS             complement(2764..4536)
                     /locus_tag="TVB59_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEL1010751.1"
                     /translation="MSNAASSIGQLNDILDGDATITQQGAFLQLQVYDYARLETILAG
                     SLRKASDFNSASKRVAYLLKRLLQSSSALVIDDLADEIGVSRSTINKDLKAAKALART
                     YSVMIQGKPNHGIQAVGTELNLRLLYVHEVYKYFEPQGLCGDSLFFLDELYQTYQLPR
                     KIQELLTKSFAITIERMRQGRYLTDPIPYYSNEVDSSAFMEELVYHIELAYQLSLSQY
                     ERQFISFPLNIQYIEDLAYQEKPLQQSIVRLYSKMIEHIKTSLLVTIDQDKLFVALHT
                     HLKLLVNRLIFHVQANDIFHGEIRYKYPLAFDMAIVAAQVLAEEFDCAIELSECSYLA
                     LYFEMMMKDAEHVTEPTVKKIAVVCTTGRGTANMICRRLSKVLGPDLLISQFSEEQFN
                     PDDNDHYFAIFTTVPLKFGQLKSPVLQITNLFDDQWLQNEWRRVHHYHQKNLATITLH
                     FARLSKGKAYTDYLTEMAELLEEKQLVDRQFGQRLLEREALQSTLFGNRIAFPHTIND
                     KETKTVLLLGLLDEPYREHDCLVEFIFLVAISKRVEAQMEADLLKIYDDIFKIASDDK
                     LQAELRSLKSQAEFIAFTKEKGVF"
     gene            complement(4830..6179)
                     /locus_tag="TVB59_001898"
     CDS             complement(4830..6179)
                     /locus_tag="TVB59_001898"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEL1010752.1"
                     /translation="MSHITFDYSKVLEQFAGQHEIDFLQGQVTEADQALRQGTGPGSD
                     FLGWLELPENYDKEEFARILKAAEKIKADSDVLVVIGIGGSYLGAKAAIDFLNSHFAN
                     LQTAKERKAPQILYAGNSISSSYLADLVDYVQDKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDKVKGAVKVEADANHWETFVVPDNVGGRFSVLTAVGLL
                     PIAASGADITALMEGANAARKDLSSDKISENIAYQYAVVRNILYRKGYVTEILANYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGYRNLFETVIRVDK
                     PRQNVIIPEMAEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGGVPNMFITLPEQDEF
                     TLGYTIYFFELAIALSGYLNGVNPFDQPGVEAYKKNMFALLGKPGFEELGAALNARL"
BASE COUNT         1856 a         1543 c         1289 g         1711 t
ORIGIN      
        1 gtacaagttg tctttaagct gaaaagaggc tatcaacagc ctcttttttt gatgatatag
       61 ataagcccaa tgcttcctta gaagagctct tctgtgagat gaccttatca cctgacatta
      121 gctgcttggc tcatgcctac agctaaagga aatgccctgc aaggatagca gcacttagcc
      181 tgctggtcta cggcgtgtct cagctgcacc taagccaagc aaagatttgt actaggctgc
      241 cctgcctgac ctgtggcagc cctttgccct tgacatgcag agtaccggga agagagctgg
      301 ctgtggagcc atcaaaagaa atggttatat gccctagctg agcaagattt ttttcaacaa
      361 cagcacctac tgctgtgatg tcatatgcca tttgatcaat gactagctga ccaccagcag
      421 agatagaccc agacacttgc ttgttgtcaa tcgtatagca aaagtctgcc aagtctgccg
      481 gtgctccctg atcaaaaaga ataagcatat tggcagcact aatcatgtct gccgcctccg
      541 atccaatagc ggtaactctt gtttcaaata cttttatcat acattctctc tcttcctatc
      601 atacgatagc tccttactga tacaaaccaa tacttgcaat ccaagcaaca acaacccgag
      661 gaacaccatt taaaaagcgt gaataaagca cagatggcac cccaacctct actgtctcag
      721 cattagcctc tgataaacca agcgctactg gaatgaaatc acagccattt tgcgtattaa
      781 tagcaaaaag tgcaggaaga gccatttgtg gtggaatagt gccttttcca atctcaacac
      841 caatgagcgt tccgatgatt tgactaataa ccgcaccagg tcctaacagc ggtgataaaa
      901 atggcaacga acagataaag ccaatgataa tcaagcccca aatattacca gccagcggta
      961 ccatgagctt ggctagccaa ttaccaacac cagagccttg gataaaacca attaaaagag
     1021 agacaaatgc catgaatggc aaaatcgtat tgattaaggt ctggatagcc tcacgcgccg
     1081 cttggttgaa gatagcaact accttacctg ctcccatacc aatgcgggca acaaagctgc
     1141 tttctgcgcg ctgctcagta atctttttgc tagtatcata gctgctagcc tttggaactg
     1201 atgactcctt agcactagca acatgagcct gagcgtcact ggctgtgatt tgctcaagac
     1261 ctacagcaga cacgtaaatg tcctcggtaa tgtactgtgc caagggaccg cttttacctg
     1321 tcgccacgat attaatggtt ggaatgcctt ttttagggta aataccgcag cgtagggtgc
     1381 cgccacaatc cacaatagct agggctatct catcatcagg gattgaggtc acaaagccat
     1441 tgaccgcctc catacctgtt agggcagcaa ttttatcgac aatgtcaggc ttttttccac
     1501 cgccagtaat atagataaat ttgtgcttag cttctgttgg tgtaatggtt agcggcccac
     1561 catagccacc gctcccctta acaactgtaa tactgtgata agtcatcatg ctacctctct
     1621 tctataattc aatcatctta cttaatgtca caccctgctg cttggccacg taggctgtcg
     1681 taaagtcagt tacccagcca ccaacaaagt tcatgattaa cccaaccaag aggtaacgaa
     1741 tcgccaagtc catttggctc aagcctagcg tcttgatacc tgaggcaata cctaaccaga
     1801 caaacaattc tcccggatta atgtgtggaa agacaccgtt tgacgtatga caaaattgca
     1861 tttgagcggc aacatagctt ggcttgtaat actcgggcat aaagcgtccc atgctgattg
     1921 ccatcggatt acccagcata aaagctgaaa taaaaggcaa taccatgtag cgactgatag
     1981 ggtttttagc agagattttt gccaattgat tgaccctttg atctcctaaa ataccaatta
     2041 aggcattcat tgcaaccagc agcatcaaga ccaccggcac aatgccagtc atccagctga
     2101 caaaggtttc accaccaagc tggaagagct tcataaagcc ttccgcaaat cttgttatca
     2161 tttccataaa taaactcctc atatgatgta cttacaagca agacaataca aatgtactgc
     2221 ctgcttgata atagctgctt gagctggact caaaacagct tttatgttga caaggcaagc
     2281 aatcaatcct gcttttggca ccttacttga agcgtgccag cagctgcttg gcctgtaggg
     2341 tccaatcaaa ggctgaggca tattttggtg cgtcctcata gacccctgcc tcaaccctca
     2401 agaagacctc tcttgcgtcc tcaatagcca agcgcagcaa tttattttct cgtctaatca
     2461 agggattgta gcgatcaaaa taatgaatat cctgaccgat ataagctggc attggcttaa
     2521 acctggctgc cactgtcaca ccctgcattt gcctagcatc taatacctta cctgactgat
     2581 ccaaggcaaa catgacaatg gttccggccc tgattttccc ggctctacgg ccaatagcaa
     2641 cgcgcccctg tcgtctaaga ctggcataaa cagcattgaa gtgcttaagc tgtctcagac
     2701 ctagcaataa ttgaaaaagg taagcaacta tgacaaatag tccaaaaata accataaaac
     2761 tcattaaaaa actccttttt ccttggtaaa tgcaataaac tcagcttgac tttttaggct
     2821 ccttagctcc gcctgaagct tatcatcgct tgctattttg aaaatatcat cataaatttt
     2881 caagagatca gcctccatct gcgcttcaac cctcttggaa atagccacta gaaaaataaa
     2941 ctccaccaga cagtcatgct cacgataagg ctcgtctaat agacccagca gcaggacagt
     3001 ctttgtttcc ttgtcattaa tcgtatgtgg aaaggcaatg cgattgccaa ataaggttga
     3061 ttgcagggcc tcacgctcta gcaggcgttg accaaactgc ctgtcaacca gctgcttttc
     3121 ctcaagcagc tccgccattt cagtcaggta gtcagtgtag gccttcccct ttgacagacg
     3181 agcaaagtgt agggtgatgg tcgccaggtt tttctggtga taatgatgta ccctgcgcca
     3241 ttcattttgc agccactggt catcaaacag atttgtgatt tggagaacag gagattttag
     3301 ctgaccaaac ttcagcggca cagtggtgaa tatggcaaaa tagtgatcat tgtcatcagg
     3361 attgaattgc tcctcagaga attgtgagat caacaaatca ggacctagca ccttgctcaa
     3421 gcgacgacaa atcatattgg cagtgccacg acctgtcgtg cagacaacgg caattttttt
     3481 cactgttggc tctgtcacat gctcagcgtc tttcatcatc atttcgaaat aaagggccaa
     3541 atagctacac tcagacaatt ctatggcgca gtcaaactcc tctgctaaga cctgagctgc
     3601 gacaatggcc atatcaaagg ccaaggggta tttgtatcta atttctccat gaaaaatatc
     3661 attggcctga acatgaaaaa tcaaacgatt caccaagagc ttcaaatgcg tatgcaaagc
     3721 aacaaaaagc ttgtcttggt caatagtcac caagagactg gtcttgatgt gctcaatcat
     3781 ttttgaataa agcctgacaa tgctctgttg cagaggcttt tcttgatagg ctagatcctc
     3841 gatgtattgg atattcaagg gaaagctaat aaactggcgc tcgtattgac tcagtgacag
     3901 ctgataggct agctcaatgt gatagaccag ctcctccata aaggcactgg aatcaacctc
     3961 attgctatag taaggaatag gatctgtcag atacctgccc tgacgcattc gctcaatggt
     4021 tatcgcaaag ctcttggtca aaagctcttg gattttgcga ggaagctggt aggtctgata
     4081 cagctcatct agaaaaaaca agctatcacc acacaagccc tgcggctcaa agtatttgta
     4141 aacctcatga acataaagca gccgaaggtt caactcagtg ccaacagcct gtatgccatg
     4201 attgggcttg ccctgaatca tgaccgaata ggtcctagca agagccttgg ctgcctttag
     4261 gtctttattg atcgtgctgc gactgacgcc aatctcatca gccaaatcat caatgactaa
     4321 agctgaggag ctttgcagta gcctttttag aagataagct acccgcttgc tagcggaatt
     4381 aaagtcacta gccttacgta aactaccagc taatatcgtc tctaatctag cataatcata
     4441 gacctgcagc tgcaaaaagg cgccttgttg ggtgatggtc gcatctccat ctaaaatgtc
     4501 attgagctga ccaatgctac ttgcagcgtt tgacatcgtc ttttcacaaa gtcacagctt
     4561 agaaagctag cagaggagac aaaagcaaga ccttatcagc taacagcagc atattaaacg
     4621 aacagctagt gatactgatc ctactaagca tagagctcca aaagcctggc ttaaatagta
     4681 ttcaaaatag aacaagagct ctcaagaaca ataacctagc gcactacttg ccttgataag
     4741 cctaaccgac cttgaaaaga agcaaaaaaa agagcctctc acgagactct ttgttatgtt
     4801 ttagcagact agtctagcta gctctgtcat tacaagcgtg cgttgagcgc tgctcctagc
     4861 tcttcaaagc ctggcttacc aagaagggca aacatgtttt tcttgtaagc ctcaacacct
     4921 ggctgatcaa atggatttac cccattgagg tagcctgaaa gggcaatagc aagctcaaag
     4981 aagtagatcg tatagcctag tgtaaattcg tcttgctctg gaagcgtgat aaacatattt
     5041 ggcacaccac cgtctgtatg ggcaagaagg acaccatctg ttgctttttt gttgacaaag
     5101 tcaacgtctt tgccttgtag gtagccaagg ccatcaagat cctcagccat ttctgggata
     5161 atcacatttt gacgtggctt atccacacga atcactgtct caaagaggtt acggtagcct
     5221 tcttggataa attgaccaag agaatgcagg tctgtcgaga aattagctga agttgggtaa
     5281 ataccctttt ggtcctttcc ttcagactca ccagccagtt gcttccacca ttcgctaaaa
     5341 tactgcaatg atggctcata gtttgccaaa atttcagtta catagccttt gcgatagagg
     5401 atattgcgaa ctacagcata ttggtaagcg atgttttctg agattttatc tgatgacagg
     5461 tccttacgag ctgcatttgc cccctccatc agcgcggtaa tatcagcacc cgatgctgca
     5521 attggcaaca agcccacagc tgtcagcact gaaaaacgac caccaacatt atctggcaca
     5581 acaaaggttt cccaatgatt tgcatcagcc tcaaccttaa cagcaccctt gaccttatca
     5641 gtcgttgcat agatacgctt gttggcctct tcttgaccgt actttttaac aagtaattct
     5701 ttaaagacac gaaaggcgat tgcaggctct gttgttgtac cagacttaga aatcacgtta
     5761 acagagaaat ctttatcttg aacatagtcc acaagatcag caagatagct tgatgagatg
     5821 gagttcccag cataaagaat ttgtggtgct ttgcgctctt ttgctgtttg taggttggca
     5881 aaatggctgt tcaaaaagtc aatcgcagcc ttagcaccaa ggtaagagcc accaatacca
     5941 atcacaacaa gaacgtcact gtcagcctta atcttctcag ctgctttaag gatacgagca
     6001 aattcttctt tgtcatagtt ttcaggtaac tcaagccagc ccaagaaatc tgatccaggt
     6061 ccagtgccct gacgtagtgc ctgatcagcc tctgttacct gaccttgtaa aaagtcaatt
     6121 tcatgctgtc cggcaaattg ctcaagaacc tttgaataat caaatgtaat atgtgacatt
     6181 attttactcc cttaactttt aaagtttcat tagtatcata accttttcta ttcaatattt
     6241 caatgttttt tatttttggg gagggtggcc tgactttaac gacatgagga tcatttctgt
     6301 ctaaaagcag ctttgtgatg agcctagcgc ttccctatct gcttctacta tagcttactg
     6361 gggctgatcc gggtgatgtg gtagcctctt ggcatagcc
//
LOCUS       DARYNN010000082         5930 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.082, whole genome shotgun sequence.
ACCESSION   DARYNN010000082 DARYNN010000000
VERSION     DARYNN010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5930)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5930)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5930
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.082"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            333..2054
                     /locus_tag="TVB59_001899"
     CDS             333..2054
                     /locus_tag="TVB59_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1010753.1"
                     /translation="MLTLIVQHIKQKKWIYILIAMTLVIYDASLVIPTRVIQDLVDLM
                     SRHQLSSGALVRHVIILLATAVVSYGVAYLWHLHLFQEAVHFKFDIQQRAFRKLVFMR
                     TPFYEKFRSGDMITRFSTDVEALMDLIGYGLMIILYAGGMIAFIIPTMFLISWKMTLI
                     GIVPILLMMVMIYGVTKKQEHLVEEAREAISSLSDEVLETVEGIRVMRAYSKKDYLAL
                     HFAQKTQNLADKWNQVAKYRALYFPLYSVMIAISTVIILMVGLQLIASSEVTLGQVIA
                     LQLYLVSLVEPFGMLSDFILVYQTGKTSFGKINELIETSDDMEPDGQLELESFDQIAF
                     IDYSFTYANSSRPSLEKINLTLKKGQTLGIVGKTGSGKTTLVRQFLRQYPLGQGQLMI
                     NHRSVLDYKRQSLERQIGYVPQEHILFSKTVAQNIAMGKKAATTEEILEAIETAAFTR
                     DVQGMAKGLDTEIGERGLSISGGQKQRISIARAFLSQPDLLILDDSLSAVDARTETDI
                     IRHIQDERKGKTTLIVSHRLSAIQHADWVIVLDQGQIVEEGQPQQLLAQKGWYYEQYQ
                     RQQAQEV"
     gene            2056..3219
                     /locus_tag="TVB59_001900"
                     /pseudo
     CDS             2056..3219
                     /locus_tag="TVB59_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677880.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            3371..4147
                     /locus_tag="TVB59_001901"
     CDS             3371..4147
                     /locus_tag="TVB59_001901"
                     /inference="COORDINATES: protein motif:HMM:NF022077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HEL1010754.1"
                     /translation="MAEVITIANRKGGVGKTTTTLNLAYSLKELGKKVLVIDLDPQAN
                     LTRCFDMGNTENIKTIGHLLMVELEEEESYLVEGYTKSYDEIDIIPSSIFLSAVETQM
                     RAETGSERILSEIIRRVKENYDYILIDTSPSLSVLTINALCASDSVLIVADTQLFAVV
                     GINELLKTVQKIKKRVNPKLKVQGILLTMCENRTNLSKTLMEQVEEMFQKKIKVFQTK
                     IPKTVKVGEAIYSGQSIKKYAKGSSVDIAYDNLAKEICYE"
     gene            4140..5105
                     /locus_tag="TVB59_001902"
     CDS             4140..5105
                     /locus_tag="TVB59_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003033515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB N-terminal domain-containing protein"
                     /protein_id="HEL1010755.1"
                     /translation="MSKKLLKREITDAVDFLLDDGNALEQGNIQNIELDLLENYHNHP
                     FTLYTGKRLDDMVESIKENGVLNPIIVLKKDNNYEILSGHNRVNAARITKIKSIPCIV
                     KENLTDKEAYTYVIETNLIQRSFSDLLPTEKALVLKMRYEKIASQGKRNDLQKEINNL
                     DQGIIEKESKEEDKIDSRKTLGKEYNLSGASIARYLRLNELSKSWKKDVDEDKIGLTM
                     AVDLSYLSKEIQEYLYQKCEELELSLKPSDAKALHLMNRQEDLNQEMVITYLLNLKKT
                     KVKKYQNIKLSQSVYKKFFHDERKEDVEEIIEKALEIYFKEYIGQ"
     gene            5201..5857
                     /locus_tag="TVB59_001903"
                     /pseudo
     CDS             5201..5857
                     /locus_tag="TVB59_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037566.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Bro-N domain-containing protein"
     gene            5851..5925
                     /locus_tag="TVB59_001904"
                     /pseudo
     CDS             5851..5925
                     /locus_tag="TVB59_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         2005 a          939 c         1298 g         1688 t
ORIGIN      
        1 cactgaaaac gtttaaaatg caaacattgg aagcgttttt tgtaaaaaaa tagaagaact
       61 atccaaaaaa ggctttacaa gcccagtatt ctatgataag atgttaggca gattaaaaga
      121 aaggagaaat taataatgat ccgtttcatt caactattta accattatta cgatagtctc
      181 ctttctaacc aaaacagtta gtttctttta gtttcactaa atagaaatag tagagcccgc
      241 ggtaggaagg atatcttatt gcgggctttt tgtgtgcaaa aatcctattt taagacagct
      301 tgaaataggt tagttcagaa atggaggata tgatgctgac cttaattgtt caacatatta
      361 agcaaaagaa atggatttat atccttattg caatgacttt agtgatatat gatgcctcac
      421 ttgtgatacc aacaagggtt attcaagact tggttgattt gatgtcaagg catcagctaa
      481 gctcaggggc attggtgagg catgttatca ttcttttggc tacggcagta gtgtcttatg
      541 gggttgctta tttgtggcat cttcatttat ttcaggaggc agttcatttt aagtttgata
      601 ttcagcagcg tgcctttcga aagcttgttt ttatgagaac gcctttttat gagaaatttc
      661 gctcaggtga catgatcacg cgtttttcaa cagatgtcga agcacttatg gaccttatcg
      721 gctatggctt gatgattatc ctatatgctg gtggtatgat tgcttttatt attccgacca
      781 tgtttttgat ttcttggaaa atgaccttga taggaatagt accgattttg cttatgatgg
      841 tgatgatcta tggtgtgacg aaaaagcaag agcatttggt tgaagaggcg cgtgaggcga
      901 tttcaagcct tagtgatgag gtactagaaa ccgttgaggg cattagagtg atgcgtgctt
      961 acagtaaaaa agattatttg gcacttcatt ttgctcaaaa gactcagaat ttggcagata
     1021 aatggaatca ggtggccaag tatcgtgcct tgtactttcc tctttacagc gtcatgattg
     1081 ccattagtac agtaatcatt ttaatggtag gcctacagct catagcaagc tcagaggtaa
     1141 cacttggtca agtcattgcg ctgcagcttt atctggtgtc tttggtggag ccctttggca
     1201 tgctgtcaga ctttattttg gtttatcaga caggaaagac ctcttttggt aagattaatg
     1261 aactcatcga aacaagtgat gatatggagc ctgatggcca gcttgagtta gagagctttg
     1321 atcagattgc ttttatagac tatagcttta cctatgccaa tagttctagg cctagcttag
     1381 aaaagatcaa tttaaccctg aaaaagggac aaaccttagg gattgttggt aaaacaggct
     1441 ctggtaaaac aacccttgtc aggcagtttt tgagacaata ccctcttggg caggggcagc
     1501 tgatgattaa tcatcgtagt gtcttggatt ataagcgtca atcacttgag cgtcaaattg
     1561 gctatgtgcc acaggagcat atcctgtttt caaaaacggt tgctcaaaac attgcgatgg
     1621 ggaaaaaggc agctacaact gaggaaatct tggaggcgat tgaaactgcg gcctttacgc
     1681 gtgatgttca aggaatggca aagggcttgg atactgagat tggagagcgt ggtctgtcta
     1741 tttcaggagg tcaaaagcag cgtatttcga ttgccagagc ctttttgtcc cagccagatt
     1801 tgctgatttt agatgattcc ctgtcggcag ttgatgctag aacagagact gatattattc
     1861 gacacattca agacgaaaga aagggaaaga caacacttat tgttagccat cgcttgtctg
     1921 cgattcagca tgccgattgg gttattgttc tggatcaggg gcagatagta gaggaaggtc
     1981 agccccaaca acttttagct cagaagggct ggtattatga acagtaccag cgtcagcagg
     2041 ctcaggaggt ttaagatgac cctatttata aaattaataa aagaaattaa agctgtgacc
     2101 ttggcttttt ccctggcaat aggctttttg ctagtggcaa cagctggagg tcagatggct
     2161 cccttattgt tgcaacaaac gattgatcat tacttgactc cgatagctag aggaaaagag
     2221 gtaccgattg aaggctttca gcgcttgctc ctgctgtatt tgctgttaat tgtgataaca
     2281 gcagttttgc gttatatctc ttatcgaatg ctggtttatt cctctaatag gatcgttgct
     2341 aatcttcgta atcgagcctt tgatgtcatg cagaggctgc cgatagctta ttttgatcat
     2401 cagcctgcag gaaagattgc aactaggatt gttaatgata ctgaaaccct gaagaatcaa
     2461 ttttatgata accttttgtc tcaaattatt gtcagtcttt cacaaattat ttttatttat
     2521 gtggtgatga tttaccttga tgtgaagtca ggcttgctgt tgctgcttat tatgccactc
     2581 ttttatggca tgcaatggct gtataaaagc ttgactgacc agccaatgaa ggatttttat
     2641 caggctagga gcgctgtcaa cacacaagtc aacgaaacca tgaatggtgt ttctattatt
     2701 cagctttatc atcaagagga tacgatctta gaggaatttg aagagcagat ccaccagatg
     2761 aaaacagctg atgataggat tatttttgca gagtcagttg cttcatggac cctgacggaa
     2821 ttggtaaagt atggcatgat tgccgctatt ttggctgtta ttggttacca gttcttgcag
     2881 gggagatcag gcatcacagt tggtaagctc tttatttacg tcaattattt gctgcgcttg
     2941 tttgatttat taagtatgct ggttaggcag ctacctaata ttcagcgctc aacagcgaca
     3001 ggaacgcgcc taatgaagct gcttgaggcg cagacagagc cggataaagc acgagcaatt
     3061 gagctaacag atggtactgt ggattttacc aaggtgtatt ttgcttacga aaatggcaag
     3121 acagttttat ctgatattac cattcatgct gataaagggg agacggttgc cctagtaggg
     3181 catactggct ctggggacaa tgctataatg atgatagtac aataaatcca agtaaaatca
     3241 atggttaaag gcttccgcaa aacttttaaa cttgatgatg gattgaggct atcatctttt
     3301 tttatatcta aaattatata aaagtatagc ataaaatgaa atctctgtat agagaagaag
     3361 gagggacttt atggcagaag tgataaccat agccaatcga aaaggcggag ttggaaaaac
     3421 aactacaact ctaaaccttg cctattcact aaaagaactg gggaaaaaag tattagtcat
     3481 tgaccttgat ccacaagcta atcttacaag atgttttgat atgggaaata cagaaaatat
     3541 aaaaaccata gggcatttgt taatggtaga actggaggaa gaagaaagct atttggtaga
     3601 gggctatacc aaatcttatg atgagataga tattatcccc tcaagcattt tcttatccgc
     3661 cgttgaaaca caaatgagag cagaaacagg aagtgaacgt atattatcgg aaattattag
     3721 gagggtaaaa gagaattatg actatattct catagataca tcaccatcac ttagtgtttt
     3781 gactataaat gctctttgtg cctcagacag tgtccttata gtagcggata cacagctgtt
     3841 cgcagttgtt ggaatcaatg aacttttaaa aactgttcaa aaaataaaaa agagagtgaa
     3901 tccgaaactg aaagtgcagg ggattttact aaccatgtgt gagaatagaa ccaatctgtc
     3961 caaaacactg atggagcaag tagaagaaat gttccaaaag aaaatcaagg tctttcaaac
     4021 caaaattccg aaaacagtta aagttgggga agccatctat agcgggcaaa gcataaaaaa
     4081 atatgcaaaa ggcagtagtg tagacattgc ctatgacaat ctggcaaagg agatctgcta
     4141 tgagtaaaaa acttctaaag agagaaatca ccgatgccgt agattttttg cttgatgatg
     4201 gaaatgcctt ggaacaagga aatatacaga atatagaact tgatttgctt gaaaattatc
     4261 ataatcatcc gtttacttta tatacaggta agagattaga cgatatggta gagagcatta
     4321 aggaaaacgg agttcttaat ccaattatcg tcttgaaaaa agataacaac tatgaaatac
     4381 tttccggaca caatagagta aatgcagcaa gaattacaaa aataaaaagt attccttgta
     4441 ttgttaaaga aaatctaacg gataaagaag cctataccta tgtaattgaa acaaacctta
     4501 tacagcgttc tttctccgat ttactgccga cggaaaaagc ccttgttctt aaaatgagat
     4561 atgaaaaaat agcaagtcag ggcaagagaa atgatttgca aaaggagata aacaatttag
     4621 atcagggaat tatagaaaag gaaagtaaag aggaagataa aatagacagc agaaaaacac
     4681 ttggaaaaga atataatctt tcaggggcat ctattgcaag gtacctaaga ttaaatgaat
     4741 tatctaagtc ttggaaaaaa gatgtggatg aagataaaat aggtttgacg atggcagtag
     4801 atttatccta tctttccaaa gaaatacagg aatatctgta tcagaagtgc gaagaattgg
     4861 aactaagttt aaaaccaagc gatgccaaag cactccatct gatgaacaga caagaagatc
     4921 tgaatcaaga gatggttata acatacttgc tgaacttgaa aaaaacgaag gtaaaaaagt
     4981 atcagaatat caaactatct cagagtgtct ataaaaagtt ttttcatgat gaaaggaaag
     5041 aagatgtaga agaaattata gaaaaagcat tggaaattta ctttaaggaa tatattggtc
     5101 agtgaaaaga caaaattata aatttaaggt ataatataag gtattaaaaa gggaaaagac
     5161 ctgtttaaca ggataagata taaaagaggc aggtgtcaga atggacgaaa taaaattgta
     5221 tgaaaataaa gagatacgct ccatttggga cgaagaaaaa gaagagtggt atttttcagt
     5281 agtcgatgta gttggagttt tgacagaaca agaaaacgta agaggtgcta gtacctattg
     5341 ggctgtacta aaaaagagat taaaagaaga aggaaatgaa ctgcttacaa tttgtaagca
     5401 gttgaaaatg aaagcaacag atggaaaaat gcgtttaact gatgtagcag atatgcaagg
     5461 aatattccgt attatccagt ccatcccatc ccctaaagca gaacctttta agttatggct
     5521 tgctgaggtt ggaaaagaac gaattgatga aattatcgat cctgaactta cgattgacag
     5581 agccttagaa acttatctaa agaagggata tacacgtgag tggataaatc aaagacttca
     5641 agccattcag gtaagaaaag aactgactga tgcttgggat gaccatggga tacaaaaagg
     5701 caaagaatac gcaattctta ctgatgaaat caccaaagca tggtccggaa tgacaacaag
     5761 aggttataaa aatctgaagg gtttgaaaaa ggaaaatcta agggataata tgaccactct
     5821 tgaaatagtt cttaatatgc ttgcagaagc cacaacaaca aacgcattaa agcaaagcta
     5881 aaaggactta gccctgtgca atacagaact aaatcctttc actaatatgt
//
LOCUS       DARYNN010000083         5751 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.084, whole genome shotgun sequence.
ACCESSION   DARYNN010000083 DARYNN010000000
VERSION     DARYNN010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5751)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5751)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5751
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.084"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            48..323
                     /locus_tag="TVB59_001905"
     CDS             48..323
                     /locus_tag="TVB59_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VRR-NUC domain-containing protein"
                     /protein_id="HEL1010756.1"
                     /translation="MRTEKDIENYLKKKTKGLCLKFTSPGTIGVPDRIVVMNTGTFFV
                     EVKAPGKKPRPSQVAMHKKIKEAGQHVWVVDSYESVDMALKEMENWV"
     gene            320..1642
                     /locus_tag="TVB59_001906"
     CDS             320..1642
                     /locus_tag="TVB59_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEL1010757.1"
                     /translation="MRLHEYQEYAKTWIVEHPYCGLLLDMGLGKTLTTLSAIDEIQNI
                     FSEDHKILIVAPKKVAEETWPTEIEKWHFDFTYSKVLGSEGKRIEALETEADIYLINR
                     ENVTWLVEYYKTKWPFTFVVIDELSSFKSSKSKRFRALRKVRPKVQRLVGLTGTPAPN
                     SLIDLWPQIYLMDRGDRLETSQTRFKDKYFVPDKRNGPIVYSWTLRDGAEAEIYNKIE
                     DICVSMKAKDYLKLPPRTNNVVSVKLSNMKAYKQLEADLVLEFKDKEISAANSAVLVN
                     KLLQMANGAIYDADKTTVAIHDDKLDALEDIVEESQGQPILVFYQYQHDLERLKKRFP
                     QAEELTSVDKWNSGRIPILLCHPQSAGHGLNLQKGGHIIVWFGLTWSLEYYQQANARL
                     DRQGQTEPVIVHHIVAENTVDEKVLRILQGKEKNQNALLEAVKAQLGV"
     gene            1643..1810
                     /locus_tag="TVB59_001907"
     CDS             1643..1810
                     /locus_tag="TVB59_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010758.1"
                     /translation="MKKEYVVRIYTGREKNFEAKPQFEEKTFTRKADMLRFWDSCEAA
                     VKEKYTREWKK"
     gene            1807..1980
                     /locus_tag="TVB59_001908"
     CDS             1807..1980
                     /locus_tag="TVB59_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010759.1"
                     /translation="MTKQELIEEIEDEINDIDLLIDDYQYEIDELERDIDELDTQKDI
                     LKRKLDNLLESVE"
     gene            1980..2249
                     /locus_tag="TVB59_001909"
     CDS             1980..2249
                     /locus_tag="TVB59_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010760.1"
                     /translation="MTEQQMIDCLLYELAKKDKAIKNKSIIIAVLTAVLCLVSVLSIA
                     LQNHYEPQITGLQSQLRRTQYQLKRASEDRARQTKRIAELTGNGG"
     gene            2452..2868
                     /locus_tag="TVB59_001910"
     CDS             2452..2868
                     /locus_tag="TVB59_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF722 domain-containing protein"
                     /protein_id="HEL1010761.1"
                     /translation="MSRLSNAQLKAFDEWLFDYRFIDNKIALRKLELQTDMNTEVDKN
                     IGGGRANFVSKVTEDVVARWDSDRELKGLSNFKEAVIATLNLLDEELTDIFNLRWGVG
                     SSNTWEEIAYTRHLSRKSIYRKRERILEIFSKKIGM"
     gene            2958..3410
                     /locus_tag="TVB59_001911"
     CDS             2958..3410
                     /locus_tag="TVB59_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEL1010762.1"
                     /translation="MLGGDGKLSKLTLKQKRFADEYIISANATAAAIKAGYSKKTARS
                     IGQENLTKPDIKAYIDERLEKLESEKIATQEEVLQYLTSIMRGDQQEKTLISVGEFGQ
                     KIVDIDVGAKDRIKAAELLGKRYRLFTDKVEMDVSSDVTINVGEWDDD"
     gene            3400..4677
                     /locus_tag="TVB59_001912"
     CDS             3400..4677
                     /locus_tag="TVB59_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEL1010763.1"
                     /translation="MTTKQRPKINIVIKHPSKVFNKHIYDKLYNYSNFTEVHYGGASS
                     GKSHGVFQKIILKALNPKFKHPRKILVLRKVGATVRDSVFADIMSNLSYFGILDKCKI
                     NMSAFRITLPNGSEFIFKGMDNPEKIKSIKGISDVVMEEASEFTLDDYTQLTLRLRDK
                     KHLEKQIYLMFNPVSKVNWVYKAFFVKTPKNTVVYQTTYKDNRFLDDVTRENIEELAD
                     RNEAYYKIYALGQFATLDKLIFPKYDKQILNKDKLSHLSSFFGLDYGFINDPSAFLHV
                     KIDDANKKLYVIEEYVRKNLTNDKIANAIKDLGYAKEEIRGDSAEKKSNQELRNLGIP
                     RMIDVTKGPGTVMQGIQYLLQYDWVVDERCVKTIEELENYTWKKDKKTNEYINEPVDS
                     YNHCIDAIRYAVQDRIYQSADRSKRMKNAKYYF"
     gene            4693..>5751
                     /locus_tag="TVB59_001913"
     CDS             4693..>5751
                     /locus_tag="TVB59_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEL1010764.1"
                     /translation="MEEKQFLAGTRFNENANKQFIMLQEDFEAIDYESKLWIDQLKNY
                     ISRFKAEQLERLKELKRYYLGDNNIKYRPAKTDKYAADNRIASDFAKYITVFEQGYML
                     GVPVEYKNENKDLQAAIDLMSVRNNEDYHNVKIKTDLSIYGRAYELLTVEEIDDKKTE
                     VKLYQLPAEQTFVIYDDTYQRNSLMAVHFYDIDYGSGKRKQIIKVYTSDTIYTYEDYN
                     LETKGTCLKEHEEHFFKGVPVNEYANNEERTGAYESVLDNIDAYDLSQSELANFQQDS
                     VNALLVIAGNAYTGADENDYLDDGRLNPNGRLAISIGFKKAQVLILDDNPNPNGVKPQ
                     AYFLKKEYDTAGSEAYKNR"
BASE COUNT         2019 a          932 c         1262 g         1538 t
ORIGIN      
        1 gttgaaaaaa aacgtaaccc tgacctttat tgaccaaagg aggaaagatg aggactgaaa
       61 aagatattga aaattatttg aaaaagaaaa caaaagggct gtgtttaaaa tttaccagtc
      121 cagggacgat aggagtacct gacagaattg ttgtcatgaa tacgggaacc ttttttgtag
      181 aggtcaaagc gccaggcaaa aaaccaagac ccagccaagt tgccatgcac aaaaaaataa
      241 aagaggctgg gcagcacgtt tgggttgttg actcctacga atcagtggac atggccttaa
      301 aagaaatgga gaactgggtg tgagactgca cgagtaccaa gaatacgcta agacatggat
      361 agtagagcac ccttattgcg gccttttact tgacatgggc cttggtaaaa cgctgacaac
      421 actatcggcg atagatgaga ttcaaaatat tttttccgag gatcataaga ttttaatcgt
      481 agcccctaaa aaagtggcgg aagaaacgtg gcctacggag attgagaaat ggcattttga
      541 tttcacctac tctaaagttt tggggagcga gggaaaacga attgaggcgt tagaaacaga
      601 agctgatatc tatttgatta atcgtgagaa tgttacttgg cttgttgaat actacaagac
      661 taaatggccg tttacctttg ttgttattga tgagctgtca agctttaagt ctagtaagtc
      721 aaaacggttt agggctttgc gaaaagttag accgaaagtc caacgccttg taggactaac
      781 aggaacccca gcgcctaaca gtttgattga tttgtggccg cagatttatc tgatggacag
      841 aggcgacagg cttgagacta gccagactcg atttaaagac aagtattttg ttcctgataa
      901 gcgtaatggt ccaatcgtgt atagctggac acttagggat ggtgcagaag cagaaatcta
      961 taacaagatt gaggatatct gtgtcagcat gaaagctaaa gactatctca agttaccgcc
     1021 gcgaaccaac aacgttgtat cagttaagtt atctaatatg aaagcttaca aacagcttga
     1081 agctgatttg gtgttggagt ttaaggataa ggaaatatct gcggctaact ctgcggtttt
     1141 ggtcaataaa ttactccaaa tggccaatgg cgctatctat gatgctgata aaacgacagt
     1201 tgctatacac gatgacaaac ttgacgcgct tgaggacata gtagaagaaa gccaaggcca
     1261 gccaatctta gttttttatc agtatcaaca tgatcttgaa agacttaaga aacgattccc
     1321 tcaggctgaa gagttgacgt cagttgacaa gtggaattct ggaagaatac caattcttct
     1381 gtgtcaccct caatcagctg ggcatgggct taatctacaa aaaggcgggc atattattgt
     1441 ttggtttggg ctaacgtgga gtcttgaata ttatcagcaa gctaatgcca gattagatag
     1501 acaagggcag acagaacccg ttattgtgca ccacattgtt gcagaaaata cagttgatga
     1561 aaaagtactt aggattttac aaggcaaaga aaaaaatcag aacgccttac ttgaagcagt
     1621 taaggcgcag ttaggggtct agatgaaaaa agaatatgtc gttagaatct acacgggtag
     1681 agaaaagaat tttgaggcaa aacctcagtt tgaagagaaa acctttacgc gaaaagcaga
     1741 catgttgagg ttttgggatt cttgcgaagc agcagttaaa gaaaaatata ctagggagtg
     1801 gaaaaaatga caaaacaaga actaattgaa gaaatagaag atgaaatcaa tgacatagat
     1861 cttttgattg acgattacca atacgaaatt gacgaattag aacgagatat agacgaatta
     1921 gatactcaaa aagatatttt gaagcgtaaa ttagataacc tgttagaaag cgtggaatga
     1981 tgactgaaca acagatgatt gattgcctgc tttatgagtt agcaaaaaaa gacaaagcaa
     2041 tcaaaaataa aagcatcatt atcgctgtac taacagctgt gctgtgtctc gtgtctgttt
     2101 taagcatcgc actgcaaaac cactacgaac cacaaattac aggtttacag tcacaattac
     2161 gcaggacgca gtatcagctt aagcgagcta gcgaggatag agctagacag acaaaacgga
     2221 ttgcagaatt gactggaaat gggggatgat tatgttgcta attgacgaag taaaaaaatg
     2281 tgaatcatct tatgagatat ttagtaaacc agttgtacta agtagagatt tatatatttt
     2341 ttggaggata ggagatgagg atggacaata acacagcagc tgttttgaca ctgctaatac
     2401 tatttttacc ttttattatt ggaagtttta gagattaagc gaggtaacga gatgagtaga
     2461 ttatctaatg cacagctaaa ggcttttgat gaatggctgt ttgattatcg ctttattgat
     2521 aacaagattg cacttcgaaa acttgagcta caaactgaca tgaatacaga agtagataaa
     2581 aatatcggtg gaggaagagc aaattttgtt tcaaaagtta ctgaggatgt ggttgcaagg
     2641 tgggattcag atagggaact aaagggtcta tccaatttca aagaagcagt tattgcaacg
     2701 ctaaatcttt tggatgaaga actaactgat atttttaatc ttaggtgggg cgtcggttca
     2761 agtaacactt gggaagaaat tgcctataca agacatctgt cgcgtaagtc tatttaccgc
     2821 aaaagagagc ggattctaga aatattttcc aaaaaaatag gaatgtgaca caaaaatgta
     2881 tggaattgtc atctttttga tgataaattg gtagtatgag tttgaaggta aggcagatag
     2941 tgtcttgcct ttttgctatg cttggaggtg atggaaaatt gagtaaatta accctaaaac
     3001 agaagcgttt tgcagatgag tacatcatct cagctaacgc gacagcagcg gctattaaag
     3061 cagggtatag taaaaagaca gcaaggtcaa taggtcaaga aaacttgacc aaacctgaca
     3121 ttaaagctta tatagacgag cggcttgaaa aacttgaatc tgaaaagatt gctacgcaag
     3181 aagaagtcct acaatatctc acttcaatta tgcgaggaga ccaacaagaa aagacgctca
     3241 ttagcgttgg agagtttggc cagaagatag ttgacatcga tgttggtgcc aaggatagaa
     3301 tcaaggcagc tgagctacta ggcaaacggt acaggttatt tactgacaag gttgaaatgg
     3361 atgtcagctc agatgtaacc attaacgtag gtgagtggga tgacgactaa acagcgccct
     3421 aaaattaata tcgtgatcaa gcatcctagc aaagttttta acaaacatat ctacgacaaa
     3481 ctttacaact atagcaactt cacggaagtt cattatggtg gggcgtctag cggaaagtct
     3541 cacggtgttt ttcaaaagat aattttaaaa gcacttaacc ccaaattcaa acatcccaga
     3601 aagatattag ttctcagaaa agtcggtgca accgttagag actctgtatt tgctgatatc
     3661 atgtctaatt tgtcgtattt cggcatcttg gataaatgta agataaatat gtcggctttt
     3721 agaataacgc tcccgaatgg ctcggaattc atttttaagg gtatggataa ccctgagaag
     3781 attaagtcaa ttaaggggat atctgatgtc gtcatggaag aagctagtga atttacgctt
     3841 gatgattata cgcagttgac tttgcgttta agagataaga aacatctaga gaagcaaata
     3901 tacttgatgt ttaaccctgt gtcaaaagta aactgggttt ataaagcctt cttcgttaag
     3961 acacctaaga atacagttgt ctatcaaaca acttataaag acaaccgctt cttagatgat
     4021 gtcacgagag aaaatattga ggaactagcc gataggaatg aagcttacta caaaatatat
     4081 gctcttggcc agtttgctac acttgataaa ctaatttttc ccaaatatga caagcaaata
     4141 ttaaacaaag acaagttatc acacttgtct tctttttttg gtttggacta tgggtttatc
     4201 aatgaccctt cggcattttt gcatgttaaa atcgatgacg caaacaagaa gttatacgtc
     4261 atagaggaat atgtcagaaa gaatttgacc aatgacaaaa tagcaaatgc tataaaggac
     4321 ctcggctatg ccaaagaaga aatcagagga gattcggctg aaaagaaatc taaccaagag
     4381 ctgaggaatt taggtattcc tagaatgatt gatgttacca aagggcctgg aaccgttatg
     4441 caaggaattc agtacctgct tcagtatgat tgggttgttg atgaaaggtg tgtcaagact
     4501 attgaagaac tcgaaaatta cacttggaag aaagacaaga aaactaatga gtatatcaac
     4561 gaaccagttg acagttataa ccactgcatt gacgccataa gatatgccgt acaagacaga
     4621 atataccagt cggcggatag aagtaagcgc atgaaaaatg ctaaatatta tttttaggaa
     4681 tgaggtgaga ctttggaaga aaaacaattt ttagcaggaa ctcgttttaa tgagaatgct
     4741 aataagcaat ttattatgct gcaagaagac tttgaagcaa ttgactatga atcaaaactt
     4801 tggatagatc aacttaagaa ttacatttca aggtttaaag cagaacaatt agagcgtttg
     4861 aaagagttaa agcgatacta tcttggggat aataacatca agtatagacc tgctaaaaca
     4921 gataaatacg cagcggataa tcgtattgca agtgattttg ctaaatatat tacggtattt
     4981 gagcaaggtt atatgcttgg tgttcccgtt gagtacaaaa atgaaaataa agacctccag
     5041 gcggctattg accttatgtc ggtcagaaac aatgaggact accacaacgt caaaataaaa
     5101 acagatttat caatttatgg aagagcctac gagctgttaa ctgttgagga aatagatgac
     5161 aaaaaaaccg aagtaaaact ctaccagctc ccagccgagc aaacttttgt tatctatgat
     5221 gatacatacc agcgaaattc gttgatggcc gttcattttt acgacataga ttatggctca
     5281 ggtaaacgca aacagattat caaagtatat acttccgaca caatttacac ctacgaagac
     5341 tataatctcg aaacaaaagg tacgtgctta aaagagcatg aagaacattt ttttaaaggt
     5401 gtaccagtca atgaatatgc taataatgag gagcgtacag gggcttatga gtctgtactt
     5461 gataatattg atgcctatga tttatctcag tccgagcttg ctaattttca acaagattca
     5521 gtcaatgcgt tgcttgtaat agctggtaat gcttacacag gggctgatga gaatgactac
     5581 ttagatgacg gacgattaaa tcctaatggt cgcttagcga tctcaattgg gtttaaaaaa
     5641 gcccaagtgt taattttaga cgataatcct aatccaaatg gcgttaaacc acaagcgtac
     5701 tttctcaaaa aagagtatga taccgccggt agcgaagcct acaaaaatag a
//
LOCUS       DARYNN010000084         5468 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.085, whole genome shotgun sequence.
ACCESSION   DARYNN010000084 DARYNN010000000
VERSION     DARYNN010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5468
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.085"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            227..1780
                     /locus_tag="TVB59_001914"
     rRNA            227..1780
                     /locus_tag="TVB59_001914"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            2002..2074
                     /locus_tag="TVB59_001915"
     tRNA            2002..2074
                     /locus_tag="TVB59_001915"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2035..2037,aa:Ala,seq:tgc)
     gene            2382..5281
                     /locus_tag="TVB59_001916"
     rRNA            2382..5281
                     /locus_tag="TVB59_001916"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            5366..>5468
                     /gene="rrf"
                     /locus_tag="TVB59_001917"
     rRNA            5366..>5468
                     /gene="rrf"
                     /locus_tag="TVB59_001917"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1577 a         1102 c         1576 g         1213 t
ORIGIN      
        1 tcgtatacta gtgaagctgt cggcgagcac tagctcaagt taatgaaaaa aaggtaaaaa
       61 aagtagttga caaaggcagt ctaagctgat agaatgtaat agttgtctcg tgagacaaag
      121 acctttgaga actgaataag acgacctaaa cgtgcgggtt acggaagtaa cctgtcaata
      181 aagaaacaag tcagtaatga cgtcgagtta agagctcaaa cactgaatta acgagagttt
      241 gatcctggct caggacgaac gctggcggcg tgcctaatac atgcaagtgg aacgcacaga
      301 tgatacgtag cttgctacaa ttatctgtga gtcgcgaacg ggtgagtaac gcgtaggtaa
      361 cctagcttat agcgggggat aactattgga aacgatagct aataccgcat aaaagtggtt
      421 gacccatgtt aaccatttaa aaggagcaac agctccacta tgagatggac ctgcgttgta
      481 ttagctagtt ggtagggtaa aggcctacca aggcgacgat acatagccga cctgagaggg
      541 tgaacggcca cactgggact gagacacggc ccagactcct acgggaggca gcagtaggga
      601 atcttcggca atggggggaa ccctgaccga gcaacgccgc gtgagtgaag aaggttttcg
      661 gatcgtaaag ctctgttgtt agagaagaac agtgatggga gtggaaagtc catcatgtga
      721 cggtaactaa ccagaaaggg acggctaact acgtgccagc agccgcggta atacgtaggt
      781 cccgagcgtt gtccggattt attgggcgta aagcgagcgc aggcggtttg ataagtctga
      841 agttaaaggc agtggcttaa ccattgtatg ctttggaaac tgttaaactt gagtgcagaa
      901 ggggagagtg gaattccatg tgtagcggtg aaatgcgtag atatatggag gaacaccggt
      961 ggcgaaagcg gctctctggt ctgtaactga cgctgaggct cgaaagcgtg gggagcaaac
     1021 aggattagat accctggtag tccacgccgt aaacgctgag tgctaggtgt taggcccttt
     1081 ccggggctta gtgccggagc taacgcatta agcactccgc ctggggagta cgaccgcaag
     1141 gttgaaactc aaaggaattg acgggggccc gcacaagcgg tggagcatgt ggtttaattc
     1201 gaagcaacgc gaagaacctt accaggtctt gacatcccga tgctattctt agagataaga
     1261 agttacttcg gtacattgga gacaggtggt gcatggttgt cgtcagctcg tgtcgtgaga
     1321 tgttgggtta agtcccgcaa cgagcgcaac ccttattgtt agttgccatc attaagttgg
     1381 gcactctagc gagactgccg gtaataaacc ggaggaaggt ggggatgacg tcaaatcatc
     1441 atgcccctta tgacctgggc tacacacgtg ctacaatggt tggtacaacg agtcgcaagc
     1501 cggtgacggc aagctaatct ctgaaagcca atctcagttc ggattgtagg ctgcaactcg
     1561 cctacatgaa gtcggaatcg ctagtaatcg cggatcagca cgccgcggtg aatacgttcc
     1621 cgggccttgt acacaccgcc cgtcacacca cgagagtttg taacacccga agtcggtgag
     1681 gtaaccgtta aggagccagc cgcctaaggt gggatagatg attggggtga agtcgtaaca
     1741 aggtagccgt atcggaaggt gcggctggat cacctccttt ctaaggaaaa aggaagcacg
     1801 tttagcgtct tatttagttt tgagaggtct tgaaataagt catgagaacg ttaagaaacc
     1861 cgtatgacaa tagggaactg acgcagagtc gtaggactca aggaagtgat tctttttcac
     1921 tagggtttta gttcgaatac agtttggctt catacagacc attgataaga gtatacatat
     1981 acaagtacat ttatagtgta cggggcctta gctcagctgg gagagcgcct gctttgcacg
     2041 caggaggtca gcggttcgat cccgctaggc tccattatct aggatacaaa gagaagtttg
     2101 ggttacctaa ttttctgtat tctaagatat ataagatata gttcaagtaa ttgaacacga
     2161 cctcattttt taggaaaaaa gataaatctc ctcgtgtgta aagcacacat cgtcgatttc
     2221 ctatttttct acaaaaatgc ccaacaagtt gggacggtct tagtatctta atcttgtcca
     2281 ttgaaaattg aataactata tcatattccg caatcaaaaa agattgtaag aaagtaacaa
     2341 gaaataaacc gaaacgctgt gataacgagt ttaaaaaata aggttaagtt aataagggcg
     2401 cacggtggat gccttggcac tagaagccga agaaggacgt gacaaacgac gaaatgcttt
     2461 ggggagctgt aagtaagcaa agatccagag atgtccgaat gggggaaccc actagctaat
     2521 ggctagtatc cataactgtt aaggttatga gaaggaagac gcagtgaact gaaacatcta
     2581 agtagctgca ggaagagaaa gcaaacgcga ttgcctgagt agcggcgagc gaaaaggcag
     2641 gagggcaaac cgaagagttt actcttcggg gttgtaggac tgcgctgtgg gacgacaaga
     2701 ttatagaaga aggccttggg aagggtcgcc aaagagagta atagcctcgt attcgaaata
     2761 gtctttaacc ctagcagtat cctgagtacg gcgagacacg aggaatctcg tcggaatctg
     2821 ggaggaccat ctcctaaccc taaatactca ctagtgaccg atagtgaacc agtaccgtga
     2881 gggaaaggtg aaaagcaccc cgggagggga gtgaaagaga acctgaaacc gtgtgcctac
     2941 aagaagttcg agcccgttaa tgggtgagag cgtgcctttt gtagaatgaa ccggcgagtt
     3001 acgtttatgt gcgaggttaa gttgaagaga cggagccgaa gggaaaccga gtcttaatag
     3061 ggcgtaagta cgtggacgta gacccgaaac catgtgacct acccatgagc aggttgaagg
     3121 tgcggtaaga cgcactggag gaccgaacca gggcacgttg aaaagtgctt ggatgacttg
     3181 tgggtagcgg agaaattcca aacgaacttg gagatagctg gttctctccg aaatagcttt
     3241 agggctagcg tcgatatgaa gtctcttgga ggtagagcac tgtttgggtg aggggtccat
     3301 cccggattac caatctcaga taaactccga atgccaatga gatatgatcg gcagtcagac
     3361 tgcgagtgct aagatccgta gtcgaaaggg aaacagccca gaccaccagc taaggtcccc
     3421 aaataactgt taagtggaaa aggatgtggg gttgcacaga caactaggat gttagcttag
     3481 aagcagctat tcattcaaag agtgcgtaat agctcactag tcgagtgacc ctgcgccgaa
     3541 aatgtaccgg ggctaaaaca gtttaccgaa gctgtggatt accgttaagg taatggtagg
     3601 agagcgttct atgtgtgatg aaggtatact gtgaagagtg ctggaacgca tagaagtgag
     3661 aatgccggta tgagtagcga aagacaggtg agaatcctgt ccaccgtaag actaaggatt
     3721 ccaggggaag gctcgtccgc cctgggttag tcgggaccta aggagagacc gaagggtgta
     3781 tccgatggac aacaggttga tattcctgta ctagagtata tagtgatgga gggacgcagt
     3841 aggctaacta aaccggacga ctggaagagt ccggctaagc agtgaggtgt gatgtgagtc
     3901 aaatgcttac atctataaca ttgagctgtg aaggggagcg aagttaagta gcgaagttag
     3961 agacgtcaca ctgccaagaa aagcttctag cgatacgtat actctacccg taccgcaaac
     4021 cgacacaggt agtcgaggcg agtagcctca ggtgatcgag agaactctcg ttaaggaact
     4081 cggcaaaatg gccccgtaac ttcgggagaa ggggcgctga ctgaaggtca gccgcagtga
     4141 ataggcccaa gcaactgttt atcaaaaaca cagctctctg ctaaatcgta agatgatgta
     4201 tagggggtga cgcctgcccg gtgctggaag gttaagagga gtgcttagcg caagcgaagg
     4261 tatgaattga agccccagta aacggcggcc gtaactataa cggtcctaag gtagcgaaat
     4321 tccttgtcgg gtaagttccg acccgcacga aaggcgtaat gatttgggca ctgtctcaac
     4381 gagagactcg gtgaaatttt agtacctgtg aagatgcagg ttacccgcga caggacggaa
     4441 agaccccatg gagctttact gcagtttgat attgagtatc tgtaccacat gtacaggata
     4501 ggtaggagcc atagaagtcg ggacgccagt ttcgatggag gcgatgttgg gatactaccc
     4561 ttgtgttatg gctactctaa cccggatagg tgatccctat cggagacagt gtctgacggg
     4621 cagtttgact ggggcggtcg cctcctaaaa tgtaacggag gcgcccaaag gttccctcag
     4681 attggttgga aatcaatcgc agagtgtaaa ggtataaggg agcttgactg cgagagcaac
     4741 acctcgagca gggacgaaag tcgggcttag tgatccggtg gtaccgtatg gaagggccat
     4801 cgctcaacgg ataaaagcta ccctggggat aacaggctta tctcccccaa gagttcacat
     4861 cgacggggag gtttggcacc tcgatgtcgg ctcgtcgcat cctggggctg tagtcggtcc
     4921 caagggttgg gctgttcgcc cattaaagcg gcacgcgagc tgggttcaga acgtcgtgag
     4981 acagttcggt ccctatccgt cgcgggcgta ggaaatttga gaggatctgc tcctagtacg
     5041 agaggaccag agtggactta ccgctggtgt accagttgtc tcgccagagg catagctggg
     5101 tagctatgta gggaagggat aagcgctgaa agcatctaag tgcgaagccc tcctcaagat
     5161 gagatttccc ataacgttaa gttagtaaga gccctgagag atgatcaggt agataggtta
     5221 ggagtggacg tgtggtgaca catggagcgg actaatacta atagctcgag gacttatcca
     5281 aaagatgaaa ccagtcgcta ttgacagctt aaggaattct tgttagacta tagttattca
     5341 attttgagtg gagaagactc gtaagttaag tgacgatagc ctaggagata cacctgtacc
     5401 catgccgaac acagtagtta agccctagaa cgcctgaagt agttgggggt tgccccctgt
     5461 gagatacg
//
LOCUS       DARYNN010000085         5342 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.086, whole genome shotgun sequence.
ACCESSION   DARYNN010000085 DARYNN010000000
VERSION     DARYNN010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5342)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5342)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5342
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.086"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            <1..892
                     /locus_tag="TVB59_001918"
     CDS             <1..892
                     /locus_tag="TVB59_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL1010765.1"
                     /translation="SVVGETDYKKACHAIKAAGYATASDYAELLIQLIEENNLQKWDK
                     EALKTNKEVTMTTANEIVQYCVDLANSGMGVDKDGCFGTQCADLPCFIVKNWFGIDLW
                     GNAIDLLNSAAAQGLEVIYNAPGVNPKASDLFVMEVAGSPYGHTGAVIEDSDGYTIKT
                     VEQNIDGNWDSLQVGGPARFNTRDFTGVVGWIRLPVDHTNQTVDTAPQTSDTIVETSK
                     TGTFTLDAAEINVRRWPNLTSEVVDSYKQGQTVSFDSEGYANGYYWISYVGGSGKRNY
                     MAIGPTDKDGNIISLWGKLN"
     gene            1056..1238
                     /locus_tag="TVB59_001919"
     CDS             1056..1238
                     /locus_tag="TVB59_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEL1010766.1"
                     /translation="MLIYDEFKQAVDNGYITGDTVAIVRKNGQIFDYVLPHEEVRNGE
                     VVTDEKVEEVMRELDK"
     gene            1436..1825
                     /locus_tag="TVB59_001920"
     CDS             1436..1825
                     /locus_tag="TVB59_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEL1010767.1"
                     /translation="MFYLAVHDQFDKKSRLAEIAKSRAGVISIDHIDCYHGTQSYLSL
                     FGKNKAGNTIIVTIEEQSEQLLLSRPSNGISAKEAQEIAYHAGARTIEAVTFGIENHK
                     RIWEVAAQNGYYLIDFKTAKVIKKEVL"
     gene            1822..3033
                     /locus_tag="TVB59_001921"
     CDS             1822..3033
                     /locus_tag="TVB59_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEL1010768.1"
                     /translation="MTKLSRRVLAMEESVTLAAGARAKALKAQGRDILSLTLGEPDFI
                     TPQHIQEKAIEAITTGKASFYTVASGLPELKDAIADYMARSYGYIPTRQEIVVGTGAK
                     YVLYAFFMAVLNPGDQVLIPTPYWVSYADQIKMVDGVPVFVQGLEENQFKVTVEQLEA
                     ARTDQTKVVLINSPSNPTGMIYSRQELEAIGNWAVQHDILILADDIYGALVYNGNQFT
                     PISALSEAIRRQTITVNGVAKSYAMTGWRLGFAVGDTDIIAAMGKIIGQTTSNVTTAS
                     QYAAIEAFGGDQTSVEEMRQAFEERLNTIYPLLNQVPGFEAIKPQGAFYFFPNVKKAM
                     EMKGFTDVTAFTDAILEEVGLAVVSGAGFGAPENIRLSYATDLATLKEAIRRLNQFMT
                     TDSSHDNKENE"
     gene            3046..4392
                     /gene="asnS"
                     /locus_tag="TVB59_001922"
     CDS             3046..4392
                     /gene="asnS"
                     /locus_tag="TVB59_001922"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEL1010769.1"
                     /translation="MTKKYVSIIDVKDHVGQEVTVGAWVANKSGKGKIAFLQLRDGSA
                     FFQAVAFKPNLIQAFGEEAGAAKFDTIRHLSQETSVLVKGIVKEDARSKFGYELDITD
                     LEVIGDSKDYPITPKEHGTDFLMDHRHLWLRSRRQAAIMQIRNAIIYASYEFFDQNGF
                     IKFDSPILSGNAAENTTELFETDYFGNPAFLSQSGQLYLEAGMMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYPFLSHEESLDLQEAYVKAMIQGVLDRAPQALELLERDTE
                     LLKRYIAEPFKRVSYDDAISLLQEHSTDDDADYEPIQHGDDFGSPHETWISNYFGVPT
                     FVINYPASFKAFYMKPVPGNEERVLCADLLAPEGYGEIIGGSVREDNYDKLLAKIKAE
                     GLNPEDYDFYLDLRKYGSVPHAGFGLGLERMVTFVAGTKHIREAIPFPRMLHRLKP"
     gene            4693..>5342
                     /locus_tag="TVB59_001923"
     CDS             4693..>5342
                     /locus_tag="TVB59_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HEL1010770.1"
                     /translation="MMNRKKHTKLIRHYSICSAVAVLAAVSLGTGQDVQASEPNPYPD
                     VRRFLDEKYDGDVDKLSKQLQGYFGSLREYIEFELKNGKQGPAGPQGPKGDKGDPGEP
                     GPQGPVGPAGPKGDRGLDGRRGPAGQQGEAGPVGPQGPQGEQGPKGDRGEQGPKGERG
                     EQGPKGERGEQGPKGDRGEQGPKGERGEQGPKGERGEQGPKGDRGEQGPKGERGEQG"
BASE COUNT         1563 a         1091 c         1358 g         1330 t
ORIGIN      
        1 atcagttgtc ggggagactg actataaaaa ggcttgtcat gcaataaaag cagccggtta
       61 tgccactgca agtgattatg cggagctgct tatccagttg attgaggaaa acaacttgca
      121 aaaatgggat aaggaagcct taaaaactaa taaggaggta acgatgacaa ccgcaaatga
      181 gattgtacaa tactgtgttg accttgccaa ctcaggtatg ggagttgata aagatggctg
      241 ttttgggacg cagtgtgcgg acttgccatg ttttatcgtc aaaaactggt tcgggattga
      301 cttatggggg aatgcgattg acctgttaaa cagtgcagca gcgcaaggtc tagaggttat
      361 ctataacgca cctggagtta atccaaaagc tagtgactta tttgtcatgg aggtagctgg
      421 cagtccttat ggacacacag gagctgttat tgaggacagt gatggctata ccattaaaac
      481 tgttgagcaa aacattgacg gcaactggga cagtttacaa gtaggtggcc ctgctcgctt
      541 taatactcgt gactttactg gcgttgtcgg ctggattagg ttacctgttg accatactaa
      601 ccagacagta gatacagcac cgcaaacgtc tgacaccatc gtggagacgt caaaaacggg
      661 tacttttaca cttgacgccg cagagatcaa cgtccgccgc tggccgaatt taaccagtga
      721 ggtagtagat agttataagc aaggccaaac cgttagcttt gatagtgagg gttacgccaa
      781 tggctactac tggattagct atgtcggagg ctcaggtaag cgtaattata tggcaattgg
      841 tcctactgac aaagacggga atattatcag tctttggggt aaattaaatt aggaggtaaa
      901 gatccgagat aagacaaaac cgctctctta atcgagggcg gttttttgtg tttcacacac
      961 atgtattcac acattggcat atccgttata acggacttgt taaaattagt ccattaaact
     1021 agacttttta cgaataataa ggtaggaggt aatttatgct aatatacgac gagtttaagc
     1081 aggcagttga taacggatat atcacaggag acacagtagc gattgtgcgc aaaaacggac
     1141 agatttttga ttatgtgttg ccgcatgagg aagtaaggaa cggggaggtt gtgacagacg
     1201 aaaaagtgga agaggtgatg agagaattag acaaataaaa aagacctcgt ccagaagtcg
     1261 gggaattgtc ggggacaacg tttgtaaatg tttctattcc aacataaaac attttttgat
     1321 ataataggaa ggatcatatg caaaggagct gaaattggac aagcacaaaa ggctcaaaac
     1381 agttttatat caatgtgcca gcttggtcgt actgctttgt cttggagtga tgagcatgtt
     1441 ttatcttgct gttcatgatc aatttgacaa gaaatcaagg ttagccgaga tagcaaaatc
     1501 aagagctggt gtcatctcaa ttgatcatat tgattgctat catggcactc agagctacct
     1561 cagtcttttt ggaaaaaaca aggcaggcaa taccatcatc gtcacaatag aggagcaatc
     1621 agagcagctc ttgcttagtc gccctagcaa tggcattagt gctaaggaag cacaggaaat
     1681 tgcctaccat gccggagcaa ggactattga agcagtgaca tttgggattg aaaaccacaa
     1741 gaggatttgg gaggtggctg ctcaaaacgg ctactatctg attgatttca aaaccgcaaa
     1801 agtgatcaaa aaggaggttt tatgaccaag ctatcaaggc gcgtgttagc aatggaagaa
     1861 agcgtcaccc tagcagcagg tgctagagca aaggcactaa aggctcaggg acgcgatatt
     1921 ttaagcctaa ctctgggaga gccagatttt ataacaccgc agcatatcca agaaaaggcc
     1981 attgaggcca tcaccactgg taaggcaagc ttttacactg ttgcttcggg gttgccagag
     2041 ctcaaggacg ccattgctga ttacatggca cgatcctatg gttatattcc taccagacag
     2101 gagattgtag tggggacagg cgccaaatac gttttgtatg cctttttcat ggctgtttta
     2161 aatcctggtg atcaggtgtt gattccgact ccttattggg tttcttatgc tgatcagatt
     2221 aaaatggtag acggggtacc ggtctttgta cagggcttgg aggaaaatca atttaaggtc
     2281 acagtagagc agctagaggc tgccagaact gatcaaacaa aggttgtttt gatcaattct
     2341 ccgtccaatc caactggcat gatttacagc cgacaggagc ttgaagccat tggcaattgg
     2401 gctgttcagc atgatattct gatcctggca gatgatatct atggtgcatt ggtctacaat
     2461 ggcaatcaat ttactccaat atcagcctta tcagaggcta ttcgtagaca gaccattact
     2521 gtaaatggcg ttgccaagag ctatgcgatg acaggctggc gtttgggctt tgcggtcgga
     2581 gacactgata ttatcgctgc tatgggtaag attatcgggc aaaccacctc taatgtgaca
     2641 acagcgtccc aatatgcagc gattgaggcc tttggcggtg accaaacgtc agttgaggag
     2701 atgagacagg cctttgaaga gcgcctcaat accatttatc ccctgctcaa tcaagttcct
     2761 ggctttgagg ctattaagcc ccaaggagcc ttttatttct ttcccaatgt caaaaaagct
     2821 atggagatga agggctttac cgatgtgaca gcctttactg atgcgatcct agaagaggta
     2881 ggactggctg ttgtcagcgg agctggcttt ggtgctccag aaaatatcag gctaagctat
     2941 gccactgatt tggcaaccct aaaagaagct atcagacgac tcaatcagtt catgacaact
     3001 gacagcagcc atgacaacaa agagaatgaa tagaaaagag acattatgac caaaaaatac
     3061 gtttccatta tcgatgttaa agaccatgta ggacaagaag tgacagttgg tgcttgggtc
     3121 gccaacaagt caggcaaagg gaaaatagcc tttttgcaat tgcgtgatgg ctcagccttt
     3181 ttccaggcag ttgcctttaa gccaaacctg atccaagcct ttggtgagga agcaggagca
     3241 gctaagtttg acacgattag gcatctcagc caagaaacct ctgtcttagt aaagggcatt
     3301 gtcaaagagg acgctagatc aaaatttggc tatgagctag acattacgga cctagaggtt
     3361 attggggatt ccaaggatta tccaattact ccaaaggagc atgggacaga ctttctcatg
     3421 gatcaccgtc acctttggct gcgctctcgc aggcaggcag caatcatgca aatccgtaat
     3481 gccatcatct atgcttccta tgagtttttt gatcaaaatg gctttatcaa gtttgatagc
     3541 ccgattttat caggcaatgc tgctgagaac acaacagagc tatttgagac agattatttt
     3601 ggcaatccag cctttctcag ccaatcaggt cagctatacc ttgaagctgg tatgatggcg
     3661 cttggtcgcg tctttgactt tggtccggta tttcgtgccg aaaaatcaaa aacgcgccgc
     3721 catctgacag agttttggat gatggacgca gaatacccct tcttatccca tgaggaatcc
     3781 ttagacctac aggaagccta tgttaaggcg atgattcagg gtgtgcttga tcgtgctcca
     3841 caggcattgg agcttctaga gcgtgacaca gagctgctga aaagatacat tgcagagccc
     3901 ttcaagcgtg tctcctacga cgatgcgatc agcctgcttc aggagcacag cacagatgac
     3961 gatgccgact atgagccaat tcagcatggc gatgactttg gctcaccgca tgaaacctgg
     4021 atttccaatt attttggggt cccaaccttt gtcatcaact acccagctag ctttaaggcc
     4081 ttttacatga agccggttcc cggcaatgaa gagcgcgtgc tatgtgcgga cctgctagca
     4141 ccagagggct acggtgagat tatcggaggc tcggttcgtg aggataacta tgacaaattg
     4201 ttggcgaaaa tcaaggctga aggcctaaat cctgaggatt atgactttta ccttgacctt
     4261 cgcaaatatg gctcagtgcc gcatgctggt tttggacttg gactagagcg catggtgacc
     4321 tttgttgcag gtaccaagca cattcgtgag gctattccat ttccacgcat gcttcatcgc
     4381 ttaaaaccat aatgaaccct atcagcgtcc gccattgggc gcttttttgc tgcgctgagc
     4441 agtacttaga gctcaagcct cccagttaga cttggcagag ctgtggctct ttgcttgagc
     4501 tattgtaggc aaaggtatca ctggatctga aaacaacaaa atcagacaag tgatatcaaa
     4561 attaaaaaaa aaaaaaaacg aaacctagga ggatcggtga gcttattagt ttggcactaa
     4621 tcatcattat gctataattg tcttcacaaa taatttagaa atagctcata tttctatcat
     4681 taaaggagag agatgatgaa tcgtaaaaag cataccaaac tcattcgtca ctacagtatc
     4741 tgctcagcag tggctgtcct agcagcagtt agcttgggaa caggtcagga cgtacaggct
     4801 tcggaaccca atccatatcc agatgtgagg cgtttccttg atgagaagta cgatggagat
     4861 gtggataaat tatctaaaca acttcaaggt tattttggta gtttaagaga gtatatagag
     4921 tttgaactta aaaatggcaa acaaggtcct gctggccctc aaggcccaaa gggtgataaa
     4981 ggagaccccg gagagccagg tcctcaaggt ccagtgggcc ccgctggtcc aaagggtgat
     5041 cgtggtttag acggacgacg tggcccagca ggtcagcaag gggaagccgg cccagttggt
     5101 cctcagggtc ctcaaggcga gcaagggcca aaaggcgacc gtggcgaaca aggaccaaag
     5161 ggtgaacgcg gtgagcaagg accaaagggt gaacgcggtg agcaagggcc aaaaggcgac
     5221 cgtggcgaac aaggaccaaa gggtgaacgc ggtgagcaag gaccaaaggg tgaacgcggt
     5281 gagcaagggc caaaaggcga tcgtggcgag caaggaccaa agggtgaacg cggtgagcaa
     5341 gg
//
LOCUS       DARYNN010000086         5325 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.087, whole genome shotgun sequence.
ACCESSION   DARYNN010000086 DARYNN010000000
VERSION     DARYNN010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5325)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5325)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5325
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.087"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(150..389)
                     /locus_tag="TVB59_001924"
     CDS             complement(150..389)
                     /locus_tag="TVB59_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEL1010771.1"
                     /translation="MAQQRRGGFKRRKKVDFIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPYVNED"
     gene            complement(548..1036)
                     /locus_tag="TVB59_001925"
     CDS             complement(548..1036)
                     /locus_tag="TVB59_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL1010772.1"
                     /translation="MINNVVLVGRMTKDAELRYTPSQVAVATFTLAVNRAFKSQNGER
                     EADFINCVIWRQQAENLANWAKKGALIGITGRIQTRNYENQQGQRVYVTEVVADNFQM
                     LESRATREANSSGSYGGGFNSSPATNSYSAPAQQTPNFGRDGSPFGGSNPMDISDDDL
                     PF"
     gene            complement(1055..1345)
                     /locus_tag="TVB59_001926"
     CDS             complement(1055..1345)
                     /locus_tag="TVB59_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEL1010773.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATIVESKDWE
                     KRRLAYEINDFREGLYHIVNLEATDAVALNEFDRLSKINGDILRHMIVKLDA"
     gene            2721..3869
                     /gene="mutY"
                     /locus_tag="TVB59_001927"
     CDS             2721..3869
                     /gene="mutY"
                     /locus_tag="TVB59_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEL1010774.1"
                     /translation="MIDLNDYGITMWDQDTIASFRRTLLAWYDQEKRDLPWRRTKDPY
                     HIWVSEIMLQQTQVVTVIPYYERFLDWFPTVEALACADEERLLKAWEGLGYYSRVRNM
                     QKAAQQIMTDFGGIFPSSHADITKLKGIGPYTAGAISSIAFDLPEPAVDGNVMRVMAR
                     LFEINYDIGDPKNRKIFQAVMEVLIDPERPGDFNQALMDLGTDIEAAKNPRPDESPVR
                     FFCAAYRHGTYDKYPIKEPKKKPRPIQVQAFVIRDSKGRLLLEKNTQGRLLGGFWAFP
                     LIETKLVSQQLTLFEDSPIVLETMSQTTLFEERYGLMPIWSQATFPQVKHTFSHQKWT
                     IELCEGFTDSMPLAPDRELVWVAIEDMAAYPMATPQKKMLEAYLKKQS"
     gene            4640..>5325
                     /locus_tag="TVB59_001928"
     CDS             4640..>5325
                     /locus_tag="TVB59_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface-anchored protein"
                     /protein_id="HEL1010775.1"
                     /translation="MNKKSARRRRKNLITKLAMTSALTLGVGAATTLAGQTEVRADNI
                     LRLDMTDKEAVEKFANELKNEVHKNYRGSNTWQKLTLILNGYQNLREQIETELKNSEQ
                     KVKELNDKVNSETQGKQELQNQLEKEKEELETLKKELEAEKAKGTGETEKLQKEIEAK
                     NAMISDLQKQLEETKQRVQEFEAEVGKLMAEKADLQTKLNEQEQLNAKLQKEIEDLKA
                     QIEKLKHCQDT"
BASE COUNT         1622 a         1165 c         1062 g         1476 t
ORIGIN      
        1 cttagatgag gagtttttct ttagccctat gcttcatcaa acaccaccag ataccacact
       61 ctcaatcaga tcacaggcta aggcttgacg acgctgctca gctgacttca gaccacataa
      121 aaaacagccc ttaaggactg tttcagatat tagtcttcgt ttacgtaagg cataagtgcc
      181 ataacacgag cacgtttgat agctgttgtt actttacgtt ggtttttagc tgatgttcct
      241 gttacacgac gaggaaggat tttcccacgt tctgaaacga aacggctaag aagctcagta
      301 tctttgtaat caacatattc aattttgtta gctgcgataa agtcaacttt tttacggcgc
      361 ttgaatccgc cacgacgttg ttgagccatg tgttatctcc tttatattat tcacatgata
      421 aatttgctgc ctaataagca aaccgacgcc agaaagaggc ctcaatcttt tgtgcttgaa
      481 agcaactcct ctgtctccca agctaccagc aaatctatgc aattcatgtc agtccacttt
      541 ccattgctta gaatggaaga tcgtcatctg aaatatccat tggatttgag ccgccaaatg
      601 gacttccatc tctgccaaag ttaggtgttt gctgagcagg cgctgaatag ctattggttg
      661 ccggtgagct attaaaacca ccaccatatg agccagacga gttcgcctca cgtgtagcac
      721 gactttccag catttggaaa ttatctgcaa caacctcggt tacatacaca cgctgcccct
      781 gttggttttc gtagttacga gtctgaatac gtcccgtaat cccaatcaag gcaccctttt
      841 tagcccagtt agctaaattt tcagcttgct gacgccagat cacacagtta atgaaatccg
      901 cttcgcgctc accattttgg ctcttaaagg cgcgattaac agcaagtgta aacgtagcaa
      961 ctgccacctg acttggagtg tatcgaagct ctgcgtcctt ggtcatacga ccaactagta
     1021 ctacattatt aatcataaac tacctacttt gcaattaagc gtcaagctta acgatcatgt
     1081 gacgaagaat gtcaccgttg atttttgaca gacggtcaaa ctcattaaga gctacagcgt
     1141 cagtcgcttc aaggtttacg atatggtaaa ggccttcgcg gaaatcattg atttcgtatg
     1201 caagacgacg cttttcccaa tcttttgatt caacaatagt tgcaccattg tcagtcaaga
     1261 tagagtcaaa acgtgctacc aaagcgtttt tagcttcttc ttcaatgttt ggacgaatga
     1321 tataaagaat ttcgtattta gccattgata gtttcctcct tttggtctaa tgactcgcta
     1381 cccttgtaac gagtaagtga ggtatgctca cagattaaca gtatacaata aacaaaggta
     1441 aaaagcaagc aaaatgttga cctttctgtt gaataaaaga ccttcttaga tcccttcgta
     1501 gctccataaa aagcaaagcc acttctatag aaatgacctt tagtcacctg acttgcaggt
     1561 cttagtggca aggtcaaatc cagacaccag caaaaaggac acccaaccgg gtgtccttat
     1621 catgtcttga gtgctattct cccttctatc tgccatttaa taaggagtca cctgtcaatt
     1681 gttcctctaa agaggaacac atacttatct gtctaatcag tcgtctcctt tctgtttaac
     1741 aaaatgaacg gttattaaaa gaatatgact gttcttgagt ttcgtttgtt agcactgtgc
     1801 tattttggct tacattggac tcactccttc agctattttt tgctgtcgtg ctcaatgtct
     1861 ccgtttttat atcttgcgat gtacataaga ccctcctatt agaaaagctc actagctatc
     1921 tgatgatagc tacctttcaa ataagctcaa tcctttaccc tgagtgccaa taacaatatc
     1981 aaggacgact agtgacacag caactagtct ccatttttat agcgtccttt attgaatctt
     2041 agcatagcat acgtcctttc aataacggga atttcaagct tatactgttt agagcgctcc
     2101 tttggccaaa gctggtaatc tcgataagcc ttcacatgtg atcacatatt aaattgtaaa
     2161 attggttttg cctaccgttt gttggagctc ttaatctcca tttttgtacc gcgcgacatg
     2221 tcttgttatc atcagatatc ctcctataac tccagtgtca tcggtcgtcc ttatctacat
     2281 ctttattata atgtaagcgg ttactaaagt caagcttttt gctccttttt tgataacata
     2341 tcagcaacta aaaccccacg ataggacaca agccttcagc aaagactgag aaccttttta
     2401 tacttgtcat ttacgttcaa gtgcctttgt caatacctca gagtcattaa ccttttcgcg
     2461 gtcagctaat ctaaccaacc actctgaaac ggtaacagtt ttacgaacag ctttattatt
     2521 tttgataaat ggtgttgaat cagcttgtag gaactggtaa attcagacca caatcaatat
     2581 aagcagcaag aacattttct aacatgtcat gagcagttgt cacagcctct ttataaggta
     2641 taaatcacaa agcatgcttt aacaaatcct atcggacgca gggttcaacc aattcagaca
     2701 atctgtgtta caataggatt atgatagatt taaatgatta tggcattacc atgtgggatc
     2761 aagataccat tgcctccttt cgtcgtacgc tgctagcttg gtacgatcag gaaaagcgag
     2821 acctgccttg gcgtcgcaca aaggaccctt atcatatctg ggtctcagag atcatgctcc
     2881 agcaaacgca ggtcgttacc gttattcctt attacgagcg atttttggat tggtttccaa
     2941 cggtagaggc cctcgcctgc gctgacgaag agcgcttact caaggcttgg gagggactgg
     3001 gctactactc tcgtgtacgc aatatgcaaa aggctgcgca gcaaatcatg actgactttg
     3061 gcgggatttt cccaagctca cacgctgata ttactaagtt aaagggcatt ggcccttata
     3121 cagctggcgc tatctcaagc attgcctttg atctgcctga gcctgcggtt gatggcaatg
     3181 tcatgcgagt catggccaga ctgtttgaga ttaattacga tattggagac cctaagaacc
     3241 gcaagatttt tcaggctgtt atggaggtgc ttatcgatcc ggagcgaccc ggagatttca
     3301 atcaagcctt gatggatctg gggactgata ttgaagcggc taaaaatccc agacctgacg
     3361 agtctcctgt gcgctttttc tgtgcagcct accgacatgg tacctatgac aaatacccca
     3421 tcaaggagcc aaagaaaaag ccccggccta ttcaggtgca ggcctttgtg attcgtgaca
     3481 gcaaggggcg gcttttgctc gaaaaaaata cccaagggcg cttgctaggt ggcttttggg
     3541 cctttcctct gatagagacc aagcttgtca gtcaacaact gaccctcttt gaggacagtc
     3601 ctatcgtgct tgagaccatg tctcagacaa ccctttttga ggagcgttac gggcttatgc
     3661 ctatctggtc tcaagctacc tttcctcagg tcaagcatac ctttagccac caaaaatgga
     3721 ccattgagct ttgcgagggc ttcacagaca gcatgcccct agcccctgac agagaacttg
     3781 tctgggtcgc aatagaggat atggctgctt acccaatggc aaccccacaa aagaaaatgc
     3841 tagaagccta cctaaaaaaa caaagctaag cggctcatag ctgtcagata aggtccttaa
     3901 ggcagagctt tagggacttt tttgcttgcc caaggagctt acttgtagcc tacttggtct
     3961 gatcagacaa gaaaaactcg atttcttgta acaaagtcag acgattaccc ttttcattaa
     4021 aaaaacgaaa ctacggagac aaattgggac actgctatgt cttgtcgtca gctgtcgtgc
     4081 tacactggcc ttagaaacta agcacagcca aaagctgtga aaactataac tatattatgg
     4141 aggagaaaac acaatgaagc tgacaaatgc cctatgccta gtagccgcta ctgcagccct
     4201 agccctagca ccaatcaaca caagcactgg acaaactaat accgttttgg caagtcaaaa
     4261 aagtacagga cattgtactc atactagaag tggatggttt aaatgccctg atggaggatc
     4321 atattacgac gaaagttacg atacacattc atcatggtta atttggcttt atggtgcttt
     4381 ttactctgca tgggaaatta taactagttg gttcaaataa attagtaaag caggtcaggt
     4441 tattatcggc ctgcttttct taatcagcct tgctaatgcc tgctgaattg ccagaaatca
     4501 gacaattagc cttttcatta aaaccaaaaa ccgaacgaat ctaggagaga aagtagcgga
     4561 caactatttc tctatcttga tgactgtgtt aaaatatctt cagtcaaaat taatatgtct
     4621 atcattaaag gagagagaaa tgaacaaaaa atcagcaaga cgcaggcgta agaatcttat
     4681 tacgaagctt gcgatgacaa gtgccttaac cctgggtgta ggcgcagcga ctaccctagc
     4741 aggacaaaca gaagtacggg ctgataatat cttacgctta gatatgacag ataaagaagc
     4801 agttgaaaaa ttcgctaacg agcttaaaaa tgaagtccat aaaaactatc gtggtagtaa
     4861 tacttggcaa aagcttaccc ttatacttaa tggttatcaa aaccttagag aacaaataga
     4921 gaccgagcta aaaaatagtg aacaaaaagt aaaagagctt aatgataagg ttaatagtga
     4981 aactcaagga aaacaagagt tacagaatca gcttgagaaa gaaaaagaag agttagaaac
     5041 actaaaaaaa gagcttgaag ctgagaaggc taaaggaact ggagaaacag agaagcttca
     5101 aaaggaaatt gaagcaaaaa atgcaatgat ttctgaccta caaaaacagc ttgaggaaac
     5161 taagcaaagg gttcaagagt ttgaagctga agtaggtaaa ttaatggccg aaaaggcaga
     5221 cctacaaaca aaattaaatg aacaagagca gcttaacgct aagcttcaaa aagaaattga
     5281 agacttaaag gctcagattg aaaagcttaa gcactgtcaa gatac
//
LOCUS       DARYNN010000087         4953 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.088, whole genome shotgun sequence.
ACCESSION   DARYNN010000087 DARYNN010000000
VERSION     DARYNN010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4953)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4953)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4953
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.088"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            <1..693
                     /locus_tag="TVB59_001929"
     CDS             <1..693
                     /locus_tag="TVB59_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010776.1"
                     /translation="TDDSFIAVFDPKLKEIDKHIFEDSVIASDFSVDGDDIYLLGTDV
                     KIKDNYPTYLYTLSIKNGQLAMKNKELLYEQPESTYFFHDSIVKEKQLYTALSGYRNN
                     VTKERTVLGQVFHYDMQSGQKHFFDLTEIAPVNIFDLGHDTLAIEHEKNEAGKIGFSL
                     FHLNDKTSTFIDLSQFGLSIESDYLKDVKQIDENTLLILAGHTLIGYHINDHQAIFNK
                     QVSDDAFHIWVK"
     gene            complement(1204..2832)
                     /locus_tag="TVB59_001930"
     CDS             complement(1204..2832)
                     /locus_tag="TVB59_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1010777.1"
                     /translation="MNWSTIWELVKINILYSNPQSLTALKKKQEKAPKENFKAYKSMI
                     RQQALMIALFLVIYIFMFMGVDFSQYPGLLSLYIAIFFVMATVNAFTAMYAVFYESND
                     VKLYVHLPIRSEELFIAKLISSLGMGSIFLMPLLSLFVIAYWQIIGNALAIVLAFILF
                     VVLFVSSIVFALYLNAWIGRIILRSSKRRLISAVLMFASTFGALGLIVFLNMTNNQRM
                     MADQAFSDRPLIPYFRGSYDVVVAPFSSQALLNFWLPLLLVMLMLYGLVRRIMPAYYR
                     ETLYVGGKAKNAAVARKAAASDRQQSLQRLLTKHHLATLQNATLLTQTYLMPLIYVMI
                     FITPSVTSGAQFSSYITDEYFGIALLVGVLLGSICTVPTSFVGVGISLEKDNFTFIKT
                     LPISLKGFLLNKFRLLIGLQILAPLVVYALIGLFVLGFHPVIVLSFSLGFVLMGIIQG
                     QLMFRRDYRMLDLKWQDVTQLFTRGNSQWFMLGLMFGDLIVGGFLIVLAIMCATISQQ
                     PLLVSIAVSLILLSCLLFAQLWIQRSFWKNLNKM"
     gene            complement(2837..3568)
                     /locus_tag="TVB59_001931"
     CDS             complement(2837..3568)
                     /locus_tag="TVB59_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1010778.1"
                     /translation="MIEFRHVSKLYGDKEALSDVSLTIKDGEIFGLIGHNGAGKTTTI
                     SILTSIIEASYREVLVNGQLLSEHRNTIKRQIGYVPDSPDIFLNLTAYEYWQFLAKIY
                     GVSEADTKARIEELTQLFELTQEMHNTIDNFSHGMRQKVIVIGALISNPSIWILDEPL
                     TGLDPQASFDLKEMMKEHAASGNTVLFSTHVLSVAEQLCDRIGILKKGKLIFVGTVEQ
                     LKADYPDKDLETIYLELAGRQAQEA"
     gene            complement(3605..3862)
                     /locus_tag="TVB59_001932"
     CDS             complement(3605..3862)
                     /locus_tag="TVB59_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL1010779.1"
                     /translation="MEKEQQRLYDVIKQAYDYPENRANSHLARLLLSASNQLIKNSNP
                     LTIAEQLNQALDDYLQANDLLLPKSLCGFKQSLDAYLLEKG"
     gene            4234..>4953
                     /locus_tag="TVB59_001933"
     CDS             4234..>4953
                     /locus_tag="TVB59_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL1010780.1"
                     /translation="MINKRKKKLIYRYGVCSAAVILAALASLGTCKEAKALSGPPGYP
                     LTRDFSRNFLEENTAKYLDQLREHLQHRFSELESLTRKLEKEGGTRGPAGPPGPAGPK
                     GERGEPGPVGPMGPRGEQGPKGLDGARGPEGQQGKPGPVGPQGPAGPAGQKGETGPQG
                     PRGDKGDTGETGKQGPAGERGPAGPQGPRGDKGENGAPGEQGPIGPKGETGPKGDKGE
                     RGEKGDQGQRGEKGDQGQRGEK"
BASE COUNT         1602 a         1090 c         1000 g         1261 t
ORIGIN      
        1 accgacgata gttttattgc tgtttttgat cctaagctca aagaaattga taagcatatc
       61 tttgaggatt ctgtcattgc tagcgatttt tcagttgatg gagatgacat ttacctctta
      121 ggaacagatg tgaaaatcaa ggataactac ccaacctact tatatacgct atctatcaaa
      181 aatgggcaat tagctatgaa aaacaaagag ctgctctatg aacagcctga atccacttac
      241 tttttccatg atagcattgt caaagaaaag cagctctata ccgccttaag cggctatcga
      301 aacaatgtta ccaaggagag aaccgtttta gggcaggttt tccattatga tatgcagtca
      361 ggtcaaaaac attttttcga tctcactgag attgctccag tcaacatttt tgatttgggt
      421 cacgatacac tggcaataga gcatgagaaa aatgaagctg gaaaaattgg gtttagcctg
      481 tttcacctca atgataaaac gtctactttt attgacttat ctcaatttgg tttatccatt
      541 gaaagtgact acttaaaaga tgtcaaacaa attgacgaga acaccctatt aatattagct
      601 ggtcatacat taatcggata ccatatcaat gaccatcaag ctatctttaa caaacaagtg
      661 agtgatgatg cctttcatat atgggtaaaa tagctactca gttactgaaa acaacaaaag
      721 gtcaaagcac aagtccttga ctttttagtt aaaatagtta ggctagcttt ttctaagaag
      781 ctagcctaaa ttagtagtat ttggaactgc cattaagatg tgataaagcc agcatgcttg
      841 tgatgggtta tcagaatgtc acttcaatcc aaacgtcata aaagctcttt ttgaaaatgg
      901 tttagcacat gactgttgat ctaaagctag cagctgcaac agttgagtta gcttttttcg
      961 tgaggctccc aaagctatgt gtcgagcaac atcactaaca gctttaggag cttgatcttg
     1021 atgccccaca agctagcacc gtagggcact gctagcttgc taaagctttt tgctttcttt
     1081 tttcaatagc tgctctagct tttaacatat agttactgca attactctca ctatttgagc
     1141 tagaaccaaa acttcgtcac atcttacctt ggccaatctg gagaattaat accccagagc
     1201 tatttacatc ttattcagat ttttccaaaa gcttctttga atccagagct gggcaaagag
     1261 caaacagcta agaagaataa ggctcacagc aatgctcaca agaagaggct gctgactaat
     1321 ggtagcacac ataatcgcta aaacaatcaa aaagccacca acaattaagt cgccaaacat
     1381 cagcccaagc ataaaccatt ggctatttcc tctggtgaaa agctgggtga cgtcctgcca
     1441 tttcagatcc agcatgcggt aatcacgcct aaacatcaat tgcccttgta tgattcccat
     1501 caagacaaag cctaatgaaa aggataggac aataacgggg tgaaagccta atacaaacaa
     1561 tccaataaga gcataaacca ccaagggagc aaggatttgc agccctatca gcaagcgaaa
     1621 tttgttaagc aaaaagccct ttaagctaat gggtagggtc ttaataaagg tgaaattgtc
     1681 cttttcaaga gagatcccaa caccaacaaa gctggtcggc acagtacata tacttcccaa
     1741 gagcaccccc accaaaagcg caataccaaa gtactcatcg gtaatgtagc ttgaaaattg
     1801 tgcaccactt gtcacactag gagtgataaa gatcatcaca taaatcaaag gcatcagata
     1861 agtctgtgtc aatagtgtcg cattttgcag cgttgcaaga tggtgctttg tcaacaatcg
     1921 ctgtagactt tgctgacgat cagatgcagc cgccttgcgc gccactgctg catttttagc
     1981 ttttccacca acatagaggg tctctctgta ataagccggc atgatccgtc taacaagacc
     2041 atacagcatc agcatgacca aaagcaaggg aagccaaaaa ttaagcagag cctgactgga
     2101 aaacggtgcc acaacaacat catagctgcc cctaaaataa ggaatcaaag ggcgatctga
     2161 aaaggcttga tcagccatca ttcgctgatt gttagtcata ttgagaaata caatcaagcc
     2221 tagagcacca aaggtagaag caaacatcaa aaccgctgaa atcagcctgc gcttactact
     2281 cctcagaata atcctgccaa tccaagcatt gagatacaga gcaaaaacaa tcgagctgac
     2341 aaatagcacc acaaacagga taaacgctag cacaatcgcc aaagcatttc caatgatctg
     2401 ccagtaggca atcacgaaaa ggcttagcag cggcattaaa aatatggatc ccatacctaa
     2461 tgaggaaatc agcttagcaa tgaaaagctc ctcagatctt atcggcagat gaacatagag
     2521 cttaacgtca ttactctcat aaaagaccgc atacattgcc gtaaaggcat taacagttgc
     2581 cataacaaag aaaatagcaa tataaagtga caacagtccc ggatattggc taaaatcaac
     2641 acccataaac ataaagatgt aaatgactaa aaacagagca atcatcaagg cttgctgtct
     2701 gatcatactc ttgtaggcct tgaagttctc tttgggagcc ttttcttgct ttttctttaa
     2761 agctgtcagg gactgaggat tggaataaag gatattaatc ttgactaatt cccaaatagt
     2821 tgaccaattc ataccactat gcctcctgtg cttgacgtcc tgccaattca aggtaaatag
     2881 tctccagatc cttatcagga taatcagcct ttagctgctc aactgtccca acaaaaatca
     2941 atttcccctt tttcaaaatc ccaatccggt cacacagctg ctcagcaacc gacaagacat
     3001 gcgttgaaaa aagaaccgta ttaccagaag cagcatgctc tttcatcatt tcctttagat
     3061 caaatgaagc ctgaggatcc agtccagtca agggctcatc aaggatccag atactagggt
     3121 tggagatcaa agcaccaatc acaatgacct tttgacgcat accatgtgaa aagttatcaa
     3181 tcgtgttgtg catctcctgc gtcagctcaa ataactgcgt cagctcctca atccgagctt
     3241 tggtatccgc ctcactgacg ccataaatct tagcaagaaa ctgccaatat tcataggctg
     3301 tcaggtttaa gaaaatatcc ggtgaatcag gcacatagcc gatttgcctt ttaatggtgt
     3361 tacgatgctc actcagcagc tgaccattga ccaagacctc tctatagctt gcttcgataa
     3421 tagaggtcag gatactgatt gttgtcgtct tgccagcccc attgtgacca atgagaccaa
     3481 agatttcacc gtccttaatc gtgaggctta catcactcaa ggcctccttg tcaccgtata
     3541 gctttgaaac atgtctaaat tctatcataa ctctctccta tcctaaacca gacgctcgtg
     3601 ctggtcagcc tttttctaat aaataagcgt caagcgactg cttaaagcca cacaaggact
     3661 taggcaacaa caaatcattg gcctgtaagt aatcatcaag cgcttgattt agctgctctg
     3721 caatcgtcag cggattactg tttttgatta attggttaga agctgacagc aataatctgg
     3781 ctaaatggct attagcacga ttttctgggt aatcgtaggc ctgtttgatg acatcgtata
     3841 agcgctgctg ttccttttcc atagggcctc cctctaattt tgtacgttta cgctaataca
     3901 actagttaac acttcaatca taatctttat taggcttttt gtcaatatcc tatcgccata
     3961 tttgtctctt ttcacaaaag cagatatacc aacgatgatg gcgcttactt ttgttccttt
     4021 tttagggcaa tacgggcagt cagttgtgct tcttattttt agccataggt aacaaaatca
     4081 gacgataatc gttttcatta aaaaaaaaaa aaaacgaaac tacggagaca aactaatcag
     4141 cagctatttc ttacatttag ctagcgtgtt aagatagcta ttggaaaaga tttttaggaa
     4201 tacttcatat ttctatcatc aaaggagaga gaaatgataa ataaaagaaa gaaaaaactt
     4261 atctacaggt atggtgtctg ctcggcagca gttatcctag cagcgcttgc tagcctagga
     4321 acatgtaaag aagcaaaagc attatctggt ccgccaggat acccacttac tcgtgatttc
     4381 tcccgtaact tcctagaaga aaatactgca aaatatttag atcaattaag agaacatcta
     4441 cagcacagat ttagtgaact tgagagctta acaagaaaat tagagaaaga aggcggtacc
     4501 cgaggtccag cagggcctcc ggggccagcc ggacctaaag gggaacgtgg cgaaccaggg
     4561 cctgttggac ctatgggacc tagaggtgaa caaggtccta aaggcttaga cggagcacgt
     4621 gggcccgagg gacagcaagg aaaacctgga cctgtcggac ctcaagggcc ggcaggtcca
     4681 gcggggcaaa aaggggaaac cggacctcag ggacctcgtg gagataaggg cgatactgga
     4741 gaaactggaa agcaaggacc agcaggagaa cgtgggccag ctggacctca gggaccgcgc
     4801 ggagacaagg gtgaaaacgg tgcacccggt gagcaaggcc ctattggtcc aaaaggtgag
     4861 actggaccta aaggtgacaa gggagaacgc ggcgaaaagg gcgaccaagg tcaacgtggt
     4921 gaaaagggcg accaaggtca acgtggtgaa aag
//
LOCUS       DARYNN010000088         4951 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.089, whole genome shotgun sequence.
ACCESSION   DARYNN010000088 DARYNN010000000
VERSION     DARYNN010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4951)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4951)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4951
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.089"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            <1..2766
                     /locus_tag="TVB59_001934"
     CDS             <1..2766
                     /locus_tag="TVB59_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1010781.1"
                     /translation="LKPAITSVFDTINSLIPNAVAAFARLKQSINIDFSPLGASVKEV
                     FALINTVLGDFAHTGELSGQTFDKLKAKIASLAPKVIALWAVMNPASAIATIMPLLSL
                     FGKVGLALGSLGTSVGAFGGIISSGIASASGVVGAFAATLSGLPGVFATAAGRGLSVL
                     GTMTSAMSSLVSLALAAIGPAAILGLVVAGFGLINSQFGAQIDQLLNTAVTKGPGIIQ
                     GLVKGITSKIPALIASGTQLIAKFANAITVLLPVIIQAGVQLITSLVKGIGQNATSLI
                     SSAIKIIDSFVGSIMSALPQLISVGMELLLNVVNGIVQNIPLIIQQGQQIIDSFGNSL
                     RANLPSIISNGIAILVNLVQGITQMLPTVLQTATQVITSFVSGIVQFLPQLLQGGIQI
                     IISLVQGIIQNLPQIVQSAVQIIQSLVSGLTQALPQIIAAGIQLVVQLAVALIKGLPQ
                     IISAGIQLITGLGKAMLEAIPNALSGAWEGIKSGFSSMWDQITGKSSTSTAKVSADAT
                     AMALNVGTQTTAMANQANTDTTSMLNSISQNTELANINATSNATQMANNVNAQTGTMS
                     LQGLNDSMSLASGISANMSVANINATTQAQEMASGVNGATSSMNLDAINHTLSLASGV
                     GANMGTASTSATSQAQAMSSGVSNSLASMQSNSTKAASGLSNSVTSEMSSAATSATSS
                     ANRLSSAVESGFNKAKTSATTSMNGIANAVKTGFSSINSTAKQSMANLVSAVASGMSR
                     ATAVSNNACQKILSIFRALAGQMSSAGAYAGQGFANGLASSAGTIYAIANSIAANVAA
                     TIRRALDIHSPSRVTKTLGAFTGEGFALGMAEWIGEINSLGKAYATAVTDQNWGVNST
                     VSTSAKVNNSGINTSLDNLSEEVRQSQLSEPIFEVHNEIVGDKIYTAVKEKESREQSK
                     DSYFVFA"
     gene            2778..3620
                     /locus_tag="TVB59_001935"
     CDS             2778..3620
                     /locus_tag="TVB59_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1010782.1"
                     /translation="MDLLIEKESQATRLSDFGIYNIAIEDSAPLLSVSHRAVKGRSGY
                     IYDGATFTTKTLKVKGRVTVSDVEGVLDKQDELNALLVVDEPFYVTKMYPENSDLFNF
                     ELPGESTGDLQLIGSPHKPWKYRFKVILDDTITYEFIGKTSQGLKYNLSFTLRTAELP
                     FGETKPKDITLSGGSFAYGGTAKASQLEWPFIIELTPSGGQTNFYIEIDGRRFEFKQN
                     SQLQNSDKLLLTGIATTLNGNYVNAKTNYEYFIFNPNPNKRITYKTDFLGTIRILNFV
                     ELYK"
     gene            3630..>4951
                     /locus_tag="TVB59_001936"
     CDS             3630..>4951
                     /locus_tag="TVB59_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1010783.1"
                     /translation="MITFLDHRDIEYGAISVIRHTNAVNGERSVSGEIYTNSDVLNNI
                     DRGWRLRFEDEYYVVIYAKPVDVGQKTQVSFDAIHQFFWDFSKSSIYEGLGDGSHTID
                     TYLETVFKGSGYRYKLEVGVNAFRKQSFNYKSRLDLFNEIIKATGLEFSVSGKVVRLL
                     KNIGTDLSTVVRKNFNMNDLTIEKNIDSFITYQKGFGAWTDPEDHSKGRLEAEYESPL
                     AKEYGRLEGAPLTDERFTVADNLKEALKSNVENSYKISVKIDMEDLTRAGYRCERPVA
                     GDYIMAINETLGFQERIRIVSFTSYYDATGALVKHEVTCNDIGSVKKQSVGSLSINSR
                     INQIDADIASAIEVATQALVSADGKNTVYGGTEMPKDEPKGTLKKGDILFLKVGDTTR
                     MYFWNGAEWEEPEVVNDPEQWREDLEKQISEAIEKAKKAQEEINQRTD"
BASE COUNT         1511 a          920 c         1123 g         1397 t
ORIGIN      
        1 ctgaagcccg caataaccag cgtttttgat acgattaatt ctcttattcc aaatgcagtt
       61 gcagcattcg ctaggctaaa acagtctatc aatattgact ttagcccatt aggcgccagc
      121 gttaaagagg tgtttgctct tattaatact gttcttggag attttgcaca tactggtgaa
      181 ttatcaggac agacttttga taagttaaaa gcaaaaattg cttctttagc ccctaaagtc
      241 attgcccttt gggcagtgat gaaccctgct agcgctatag caacgataat gcctttgctt
      301 tctctattcg gaaaagttgg tctagcttta ggaagtttag ggacttctgt cggggcgttt
      361 ggtggcataa tttctagtgg gatagctagt gccagcggcg ttgttggtgc ctttgcggca
      421 actctaagcg gattacctgg cgtttttgct accgcagcag ggcgtgggct atctgtgctt
      481 ggaactatga caagcgcaat gtctagtctt gtgagtttag cactggcggc cataggaccg
      541 gccgctattc taggtcttgt ggtggcagga tttggtttga ttaatagtca gtttggcgca
      601 caaatcgacc agctacttaa caccgcagtt acaaaaggtc ccggtattat tcaaggcctt
      661 gtaaaaggga ttacttctaa aataccagct ttaatagcta gtggtactca attgattgct
      721 aaatttgcaa atgctatcac agtgttatta ccagttataa ttcaagccgg cgttcagcta
      781 attaccagcc tcgtcaaagg tattggacaa aacgcaacaa gtttaattag ttcagcaata
      841 aaaatcattg atagttttgt tggctcaatt atgagtgcct tgccgcaact tatttctgtt
      901 ggaatggagc tattattaaa tgttgtcaac ggcatagttc aaaatatacc tcttattatc
      961 cagcaaggcc aacaaatcat tgatagtttt gggaacagct tacgggctaa ccttcctagt
     1021 attattagca acggtatagc tattttggtg aatcttgtac agggaattac tcaaatgttg
     1081 ccaactgttc tgcagacagc tactcaagtt attacgagtt ttgtatctgg aattgtacag
     1141 tttttaccgc agttacttca aggtggcatt caaatcatta ttagccttgt gcaggggatt
     1201 attcaaaatc taccccagat tgtacaatct gctgtacaga ttatacagtc tttagtttct
     1261 ggactgacgc aagctctgcc tcagattatc gcagcgggca ttcagcttgt tgtacaacta
     1321 gccgtagcct tgataaaggg acttccacag attatttctg cgggtattca attaattacg
     1381 ggactcggta aagccatgtt agaggctatc ccaaatgctc tttcaggagc ttgggaaggt
     1441 attaagagcg gattcagttc gatgtgggat caaatcacag gtaagagttc cacaagtaca
     1501 gctaaagtct ctgcggacgc cacggccatg gccttgaatg ttggtactca aacaacagct
     1561 atggctaatc aagccaatac agatacgaca tctatgctta atagcattag tcaaaataca
     1621 gagcttgcta atataaacgc tacatcaaat gctacacaga tggctaataa tgttaatgct
     1681 cagacaggaa cgatgagtct tcaggggttg aatgattcaa tgtctcttgc gagtggcatt
     1741 agcgctaata tgtctgtggc taatattaac gctactactc aggctcaaga aatggcttca
     1801 ggggttaatg gtgcgacttc ttcaatgaat ctagacgcca ttaatcatac gctcagctta
     1861 gctagtggtg ttggtgcaaa catgggaacc gctagcacaa gtgcaacttc tcaggcgcaa
     1921 gctatgagct caggagtgag taacagtctg gcatcaatgc agtcaaactc aactaaagca
     1981 gcctctggtc tgtctaatag cgtgacaagt gaaatgtctt ctgcagcaac ctctgcaacc
     2041 tcaagcgcca ataggttgtc ctcggcggtc gagtctggct tcaataaggc gaagacttca
     2101 gcaacaacct caatgaatgg gatagccaat gcggttaaaa caggatttag tagcattaac
     2161 agtactgcaa agcaatctat ggcaaacctt gtaagtgcag tggcttctgg gatgtctcgt
     2221 gcaaccgcgg tgtctaataa tgcttgtcag aagatcctct caatattcag ggctttggca
     2281 gggcagatgt cttctgcagg agcttatgca ggtcaaggtt ttgctaatgg tctagctagt
     2341 agcgcaggca caatctacgc aatagctaac agcattgccg ctaacgtagc agcaacaatt
     2401 agacgcgctc tggatattca ctcgccatct cgtgtcacta aaacactagg agcatttact
     2461 ggagaggggt ttgccctcgg tatggcagag tggataggtg agatcaatag tctaggtaaa
     2521 gcatacgcaa cagcagttac tgatcaaaac tggggggtaa atagtactgt ttcaacatct
     2581 gctaaagtta ataatagtgg aatcaatacc tctcttgata atcttagcga agaggttagg
     2641 cagtctcaat tgtcagagcc tatctttgaa gtgcataatg agattgttgg agataaaatt
     2701 tacacggctg ttaaagaaaa agaatcaaga gagcaatcta aagattctta ttttgttttt
     2761 gcctagaagg gagtattttg gatttattaa tagaaaaaga gagtcaggca actagattgt
     2821 ctgactttgg tatttataat attgctattg aagatagtgc tcctctacta tctgtatcac
     2881 accgagcagt caaaggaagg agtggttaca tctacgatgg ggctactttt acgactaaaa
     2941 cgcttaaggt caaaggaaga gtgacggtaa gcgatgtaga aggagttttg gacaaacagg
     3001 acgaactaaa cgctctgctt gttgttgacg aacctttcta cgtgactaag atgtaccctg
     3061 aaaactcaga tctatttaac tttgagcttc caggggaaag cacaggagac ctgcaactta
     3121 ttggctctcc tcataaacct tggaaatata gatttaaagt catcttagac gacactatca
     3181 cttatgaatt tataggaaaa accagtcaag gactaaaata taatctttcc ttcacactaa
     3241 gaactgctga attacctttc ggtgagacaa aaccaaagga cataactcta tcagggggca
     3301 gttttgccta tggaggaacc gctaaagcaa gtcagttaga gtggcctttt attatagagc
     3361 ttactccctc tggaggtcag actaattttt atattgaaat tgatggcagg cgctttgagt
     3421 ttaagcagaa tagccagcta caaaatagtg ataaattact tttgacaggc atagctacca
     3481 cactaaacgg aaattatgtc aatgctaaaa cgaactatga gtattttatc ttcaatccta
     3541 atcctaacaa gagaattact tacaaaacgg attttcttgg cacgattagg attttaaatt
     3601 ttgtagagtt gtataaatag gagggtctaa tgattacttt tttggatcat cgtgacattg
     3661 agtatggggc cattagtgtc attaggcata ctaatgctgt taatggtgag cgctcagtga
     3721 gcggggaaat ttatacaaac agtgatgtcc tcaataatat cgatagaggg tggcgactta
     3781 gatttgaaga tgagtattac gttgttattt acgcaaagcc tgttgatgtt ggtcaaaaaa
     3841 cgcaagtttc gtttgatgcc atacaccaat ttttttggga cttcagcaag agtagtatct
     3901 atgagggtct cggagatggg tctcatacca ttgataccta tctagagaca gtatttaaag
     3961 gtagtgggta ccgctataag ctagaagtag gtgtgaacgc atttagaaaa caatctttta
     4021 attataagtc taggttagat ttattcaatg agattattaa agcgaccgga cttgagtttt
     4081 cagtcagcgg gaaagttgtt cggctattaa aaaacatagg tactgatctg tcaacagtgg
     4141 tacgaaaaaa tttcaacatg aatgatctta ccattgaaaa aaatattgat agctttatta
     4201 cctatcagaa aggctttggt gcatggaccg acccagagga ccactctaag gggagacttg
     4261 aggcggaata cgaaagccct cttgccaagg agtacggtcg acttgaaggg gcgcctctga
     4321 cggatgagcg cttcacggtg gcagataatc taaaagaagc tttaaaaagt aatgttgaaa
     4381 attcttataa gatatcagta aaaattgata tggaagattt aacgagagct ggttatagat
     4441 gtgagaggcc ggttgctggt gactacatta tggcgataaa tgagacttta ggttttcaag
     4501 agcgtatacg gatagtttct tttacaagct actacgacgc aactggagct ttagtaaaac
     4561 atgaagtcac ttgtaatgat atcggatctg tgaaaaaaca aagcgtagga agtctgtcta
     4621 taaacagtag aatcaatcag atagatgcag atattgcttc tgcaattgaa gtagcaacac
     4681 aagcactagt gtctgctgac gggaaaaata ctgtttacgg tggcacagaa atgcccaaag
     4741 atgaaccaaa aggaacctta aaaaaaggag acatactatt cctaaaagtt ggcgatacta
     4801 ctagaatgta tttctggaat ggtgctgagt gggaagaacc cgaggttgtg aacgacccag
     4861 aacaatggcg tgaagacctc gaaaaacaaa tctctgaggc aatcgaaaaa gccaaaaaag
     4921 cgcaagaaga aatcaaccag cgcaccgaca a
//
LOCUS       DARYNN010000089         4833 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.090, whole genome shotgun sequence.
ACCESSION   DARYNN010000089 DARYNN010000000
VERSION     DARYNN010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4833)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4833)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4833
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.090"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            <1..822
                     /locus_tag="TVB59_001937"
     CDS             <1..822
                     /locus_tag="TVB59_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEL1010784.1"
                     /translation="AEWKLLKTPEARQAALKAADKLIERYQEKGGFIQAWGQLGKAED
                     YRLIIDCLLNIQLLFFASQETGDDRYRQMAINHFYASANNVIRDDASAYHTFYFDPET
                     GDPIKGVTRQGYSDDSAWARGQAWGIYGIPLTYRFLKDPQLIALFKGMTHYFLNRLPK
                     DQVSYWDLIFEDGSGQSKDSSATAIAVCGIHEMLKHLPENDPDKKAYQAAMHCMLRSL
                     IDSYANKDIKPGAPLLRHGVYSWHSGKGVDEGNIWGDYYYLEALLRFYKDWTPYW"
     gene            868..1356
                     /locus_tag="TVB59_001938"
     CDS             868..1356
                     /locus_tag="TVB59_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEL1010785.1"
                     /translation="MTPPNIIMTRVDERLIHGQGQLWIKFLNCNTVIVANDAVAEDKI
                     QQSLMKPVVPSSIAMRFFSIQKVIDVIHKASPAQTIFIVVKDLEDIKRLVEGGVPIKE
                     VNLGNIHKTDDKIAITQFISLGDKDKAIIRTLTHDHHIVFNTKTTPAGNGASEVNILD
                     YI"
     gene            1371..2150
                     /locus_tag="TVB59_001939"
     CDS             1371..2150
                     /locus_tag="TVB59_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEL1010786.1"
                     /translation="MDINLLQALLIGLWTAFCFSGMLLGIYTNRCIILSFGVGIILGD
                     LPTALSMGAISELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVTPEAALALST
                     PIAVAIQFLQTFTYTAFAGAPETAKKQLQKGNIKGFTFAANGTIWAFAVIGLGLGLLG
                     ALSMDTLLHLVDYIPPVLLNGLTVAGKMLPAIGFAMILSVMAKKELIPFVLIGYVCAA
                     YLQIPTIGIAIIGIIFALNEYYNKPKHATTAEQGGQQDDWI"
     gene            2137..2958
                     /locus_tag="TVB59_001940"
     CDS             2137..2958
                     /locus_tag="TVB59_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEL1010787.1"
                     /translation="MTGSNKLTKRDYLKTALRAFFLQNGFNYSNYQGIGYANVVYPAL
                     KKHFGNDKTGLYKALENNCAFYNTNPHFLPFITSLHLVMLENNRPEEETRNIKMALMG
                     PLAGIGDTLTQFCLAPLFSTIAASLASDGLILGPILFFLAMNIILTAIKIGSGLYGYK
                     VGTSFIDKLSEQMAIVSRMANIVGVTVIAGLAATSVKISVPITFAAGKVDAANAAQKF
                     VTIQGMLDKIAPALLPALFTLLMYYLIKTKKWTTYKLVILTVIIGIVGSWLGVLA"
     gene            3358..4359
                     /locus_tag="TVB59_001941"
     CDS             3358..4359
                     /locus_tag="TVB59_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1010788.1"
                     /translation="MQRKVTINDIADLAKTSKTTVSFYLNGRFDKMSQETKSRIKEAI
                     EATNYKPSIAARSLNAKATKLIGVVIGDITNSFSNQIVKGIESKAQEFGYQIIIGNSN
                     YDPSREDELIEKMLNLGVDGFIIQPTSNFRKYSRIIEVKKKRMVFFDSQLYEHRTNWV
                     KTNNYDAVYDTIQQCITKGYQSFIMVTGNPNLLSTRIERASGFIDVLEANQLQYRQMI
                     IDENQTSSQEIAQFLQGAFDKERHNLVFVPNCWALPKVFTAMKALKVSLPETGLVGFD
                     NIEWTRLSSPSITTIIQPAYEEGEQATSILIDDIEGHSKEAKQQIFDCQVNWQESTF"
BASE COUNT         1410 a         1043 c          971 g         1409 t
ORIGIN      
        1 gctgagtgga agcttttaaa aacacctgaa gccagacagg cagccttaaa ggcagcagat
       61 aaattgattg agcgctatca ggaaaaaggc ggctttattc aagcctgggg acaactcggg
      121 aaagcagaag attaccgctt aattattgat tgtcttttaa atatccagct actctttttt
      181 gccagtcaag aaacaggaga tgacaggtat cgtcaaatgg ctatcaatca cttttatgcc
      241 tcagccaaca atgtgattcg tgatgacgcc tctgcttatc ataccttcta ctttgaccct
      301 gaaacaggtg atccaatcaa aggagttaca cgccaaggct acagtgatga ctccgcctgg
      361 gccagaggac aagcttgggg aatctatgga attcccttga cctatcgctt cttgaaggat
      421 ccacagctaa ttgccttatt taaaggaatg acgcactatt tcctcaatcg cttgcccaag
      481 gatcaggtat cctattggga tttgatcttt gaagatggca gtggtcagtc taaggacagc
      541 tccgcaactg ctattgctgt ttgtggtatt cacgagatgt taaaacattt accagagaat
      601 gatcctgaca agaaagctta tcaagctgcc atgcactgta tgctcagatc attaattgat
      661 agctatgcca acaaggacat caagcctggt gctccacttt tacgtcatgg cgtttactct
      721 tggcactctg gcaagggcgt tgatgaggga aatatctggg gagattacta ctatttagaa
      781 gccctgctgc gcttttacaa ggactggacc ccttattggt aggctgatag catttagcct
      841 acaaagacta ttgttaaagg agatattatg acaccaccaa acattatcat gaccagagtt
      901 gatgagcgtt tgattcatgg tcaaggccag ctatggatca aatttttaaa ttgcaacact
      961 gtcattgtgg ctaatgatgc cgttgctgaa gacaaaatcc aacagtctct gatgaaacct
     1021 gtcgttccat caagcattgc catgcgcttt ttttccattc aaaaggtgat tgacgtgatt
     1081 cacaaagcaa gccctgctca gacaatcttt attgttgtta aggatttaga agacatcaag
     1141 cgcttggttg aaggaggggt gcccattaaa gaggtcaatc ttggaaacat tcataaaaca
     1201 gacgataaaa tcgccattac ccaattcatt tcgctaggcg acaaggacaa ggctattatt
     1261 cggacattga ctcacgatca tcatattgtc tttaacacta aaacaactcc agctggcaat
     1321 ggtgcctctg aggttaatat tttagattat atttaagaaa ggaaattgat atggatatca
     1381 atttgttaca agcactttta atcggtcttt ggacagcctt ttgtttcagc ggaatgttac
     1441 ttggtatcta caccaatcgc tgtatcattc tgtcttttgg tgtcggcatt atcttggggg
     1501 acttgccaac agcacttagc atgggagcta tatctgaatt agcttatatg ggatttggtg
     1561 tcggtgctgg tggtactgtg ccacccaacc caatcggacc tggtatcttt ggtaccttga
     1621 tggctattac cagtgctggt aaagttactc cggaagctgc cttagctctt tcgacaccaa
     1681 ttgccgttgc tattcaattt cttcaaacct ttacctatac agcttttgct ggtgctcctg
     1741 aaacagctaa aaaacagctt caaaaaggga atattaaagg ctttacattt gccgccaatg
     1801 gtaccatctg ggcttttgct gtgattggct taggacttgg tttattaggc gccttgtcaa
     1861 tggatacttt acttcatttg gttgattata tcccacctgt cctcctaaat ggattaaccg
     1921 ttgctggtaa aatgcttcct gctatcggtt ttgctatgat tctatctgtt atggctaaaa
     1981 aagagctgat tccttttgtc ttaattggtt atgtctgtgc agcttacctg caaattccaa
     2041 ccatcggtat tgccatcata ggcattatct tcgccctaaa tgaatactac aacaaaccaa
     2101 agcatgcaac aacagctgaa caaggaggtc aacaagatga ctggatctaa taagctcaca
     2161 aagcgtgatt atctgaaaac tgctcttaga gcctttttcc tgcaaaatgg ctttaactat
     2221 agcaattatc aaggaatagg ctatgccaat gtcgtttacc cagccctaaa aaagcatttt
     2281 ggcaatgaca aaacaggcct ttacaaagca ctagagaaca attgtgcatt ttacaataca
     2341 aaccctcatt tcctaccttt tatcaccagc ctacacctgg tcatgctaga aaataatcgg
     2401 cctgaagaag aaacccgcaa tatcaagatg gcactcatgg gacctctagc aggcatcggg
     2461 gataccctta cgcaattttg tttagcacca ctcttttcga ccattgctgc ttccttagca
     2521 agtgacggcc tgattttggg gccaattctc tttttcctag ccatgaatat tattctaaca
     2581 gctattaaaa ttggctctgg actctatggc tacaaggtgg ggacaagctt tattgataaa
     2641 ttaagcgaac aaatggcaat tgtatctcgc atggcaaata ttgtcggagt tacagtgatt
     2701 gctggtctag ctgctacttc tgttaagata tctgttccca tcacatttgc agcaggcaag
     2761 gtcgacgctg caaatgcagc ccaaaaattt gtgaccattc agggaatgct ggataagatt
     2821 gcaccagctc ttctgccagc cctcttcact ctcttgatgt attacctcat taaaacgaaa
     2881 aaatggacaa cctataaatt agttattcta acagttatta ttggtattgt tggcagctgg
     2941 ttaggggtgt tagcctagca gtcttagaga ttctgttaat cagtattgga gggtctccat
     3001 tagcgatgag caggtctctt ttctattggg caaagctaag cattgacacc atcaactctc
     3061 gtagcctcag tcaggtcttt tgccctgtag agcctttaag cacaagcctt tactgctagc
     3121 tgtgatgaag gcgtcctcct tctactggct tctggcacaa ttaatccttt atatctctac
     3181 aagcacatga tttagcggct gattgcgcgc caatcttaca gaaggtcgca acttaagaaa
     3241 gagtaggatc atttttgacc tcttcaaagg tcatattctt ggactgaaat attaaaacaa
     3301 ttaccattcc atatgttata ataaaactac taatgatgac aaaaaggggt ctatgcaatg
     3361 cagcgcaaag taaccatcaa tgatattgct gacttagcta aaacttcaaa aacaactgtt
     3421 tctttctacc tcaacggtcg atttgataaa atgtctcagg agacaaaaag ccggatcaag
     3481 gaggctattg aagccaccaa ctacaagcct agcattgcag ctcgcagtct caatgccaag
     3541 gctaccaaat tgatcggtgt ggttatcggt gacatcacca atagcttttc caaccagatt
     3601 gtcaaaggta ttgaaagcaa ggcgcaagaa tttggttatc agattatcat cggcaacagc
     3661 aactatgatc cttcacgtga ggacgaattg attgaaaaaa tgcttaacct aggtgtagat
     3721 ggttttatca ttcaaccaac ctctaacttt agaaagtatt cacgcatcat cgaagtgaaa
     3781 aaaaagcgca tggttttctt tgacagtcag ctctatgagc atcgtacaaa ctgggtcaag
     3841 accaacaatt atgacgctgt ttatgacacc attcagcaat gcatcaccaa aggctatcaa
     3901 agctttatca tggttactgg caatcctaat ttgctgagca cacgcatcga gcgtgcctct
     3961 ggttttattg atgttttaga ggctaaccag ctccagtatc gtcaaatgat catcgatgaa
     4021 aaccaaacca gctctcaaga aattgctcag tttctacaag gcgcatttga taaggaacgt
     4081 cacaatctgg tatttgtccc aaactgctgg gctctgccta aggtttttac tgccatgaag
     4141 gcactaaagg tatcattgcc cgaaactggt ctagttggct ttgataacat cgaatggact
     4201 cgcttgtcat caccaagtat taccactatt atccagcctg cttacgaaga aggggagcaa
     4261 gcaaccagca ttttgattga tgatatcgaa gggcatagca aggaagccaa gcaacaaatt
     4321 tttgattgtc aggttaattg gcaagaatca accttctaac aggatttttt cgccttctag
     4381 accttaaaaa atcagccatt ctaataacga tgacaaagta acacgaggct taacgcttgt
     4441 ttgctagcat cagaaaaaac acataaatca gcctgaacta cccggttgat gaaacaataa
     4501 accattaagc aacggtctta ttcctcatac caagaggagc aaggccgttt tgacgttttt
     4561 gacaatggtc gttattgtaa acgtaacggt agtgtattac tgacaggctc ttcaaaaaag
     4621 ctgtcgtcct taggtcatac gaggccttct tttacaagcg actgctactt cttcactact
     4681 agtgtgatct tttagccaat ttctgagaac atcatcagta aaatctcgca cctgccaata
     4741 atggcaagca agcttttttg accagcaagt taatcatgta tcacttgtga cttcaactct
     4801 taactgtttg tcctttcaag tctactataa gag
//
LOCUS       DARYNN010000090         4618 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.091, whole genome shotgun sequence.
ACCESSION   DARYNN010000090 DARYNN010000000
VERSION     DARYNN010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4618)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4618)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4618
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.091"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(64..624)
                     /locus_tag="TVB59_001942"
     CDS             complement(64..624)
                     /locus_tag="TVB59_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEL1010789.1"
                     /translation="MTSKRLTDQIELSLFAALIFISVELLRIPVGAQFIHLGNALVVV
                     AVLLYGARRAALVAAIGLGLFDMINGYAAVVWITVLEALVVCYLLHVIYEKLLKSVDK
                     PMIIVAIGLLAAAAKLVMNLVKYSLIAYFGAQLPLSVALWAALGKIGGSLGTALVTVI
                     AVPLLYPVFKQLRQAVKKQEASNRLG"
     gene            complement(602..1471)
                     /locus_tag="TVB59_001943"
     CDS             complement(602..1471)
                     /locus_tag="TVB59_001943"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine kinase"
                     /protein_id="HEL1010790.1"
                     /translation="MLKRVIVANDIVGVGKVALSASIPIMAACQIEQAILPTCLLSSH
                     TAIAKTPYIQSTSEGLKPFLTTWSQAGLAFDGFFSGYLYRPDDALIILDYIKKQQLPF
                     VLDPIMADKGSMYAQLTSQHLSAMRLLAQAAQLILPNVTEACLLADVPYFGETYSRED
                     LERLLSKLATLGPREIVLTGISFDDQHIGFAYYQKATETVSYHFGKRYPYHFYGTGDL
                     VSAIVSAGYFHRLAIDELLDMVISFLDKSLAATVALNRELSLGIAYEVELGSLGAAFR
                     GLLEEKDDIKTID"
     gene            1563..2834
                     /locus_tag="TVB59_001944"
     CDS             1563..2834
                     /locus_tag="TVB59_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEL1010791.1"
                     /translation="MTSKYQQIIADLELAMQSNQFKKGEKLPSIRQLSQQYHCSKDTV
                     QRALLALQYKRLIYAIPKSGYYVLGKIEEKQHSFELSLEDYNQLAYEDFRLCLNEALD
                     GKDSDLFNYYHKAEGLEELREALLPYLADNGIYANKNQLLITSGTQQALYILAQMRFP
                     NGRHHILLETPTYHRMEQLATSLGLPYQTIERDVNGINLHQLESIFKTGQIAFFYTIS
                     RFSNPLGLSYSKKEKESIVRLAEQYQVYIVEDDYLGDFASHSELPLHYYDTQHRVIYL
                     KSFSMSVFPALRIGALLLPDDLKEGFLLQKSMIDLDTNLIMQKALALYLANGMFQKNL
                     KQMRQFFNNRAHNLLDFLQKHLPNLAYQLTPQALIIQLDKAFNRKKLLKPHHTQIIST
                     RKARYMLLTISPDMPSKLLDLFSVTHEKTQE"
     gene            complement(2870..3208)
                     /locus_tag="TVB59_001945"
     CDS             complement(2870..3208)
                     /locus_tag="TVB59_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010792.1"
                     /translation="MQIIKRDGQLADFDPDKIYQALIKAARTVYVIDDSWRQHLAQVT
                     KKVVIDLEEVQAERPTINMIQSLVENRLIDAGYMTIAEHYIAYRLQRDLERNGYGDSI
                     SVHLRFEQIK"
     gene            complement(3308..4396)
                     /locus_tag="TVB59_001946"
     CDS             complement(3308..4396)
                     /locus_tag="TVB59_001946"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEL1010793.1"
                     /translation="MGYTVAVVGATGAVGQQMIKMLEESSLPISAIKLLASARSAGKI
                     LSFKGEDFVVEELTKAAFQGIDLALFSAGGNVSAKYAPYAVAAGAVVVDNTSYFRQHP
                     AVPLVVPEVNAHALDTHQGLVACPNCSTIQMMIALEPIRQRWGLERIIVSTYQAVSGA
                     GQSAIRETLAQYDQVINQGLSPKEVEASVLPSAGDKRHYPIAFNALPQIDRFTENDYT
                     YEEMKMTNETKKIMEDDTIKVSATCVRIPVLSAHSESIYIETKAVATIEAVKEAIAQF
                     PGAVLEDDTGVQRYPQAVNAVGSRETFVGRLRKDLDVEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPAQDNLFDPSVSFD"
BASE COUNT         1450 a         1081 c          843 g         1244 t
ORIGIN      
        1 tcaaatcatt agttattaat aggcttagat aacaaaaatg atgatactgc tagcaaggtt
       61 agctcaacca agcctattac tcgcttcttg cttttttact gcctgcctta attgcttaaa
      121 aacagggtat aagagaggca cagcaataac ggtcacaagg gcagtaccaa gactgccacc
      181 aattttgcca agtgctgccc acaaagcaac agacaggggt aactgggcgc caaaataagc
      241 aatcaagcta tatttcacaa gattcatgac taattttgct gctgctgcta ataagccaat
      301 tgctacaata atcatcggtt tatcaactga tttcagaagt ttctcataaa tcacatgaag
      361 caggtaacaa accactaagg cttcaagcac tgttatccag accacagccg catagccatt
      421 aatcatatca aacagtccta gaccaatggc tgccaccaaa gctgcccttc tagcaccata
      481 caataaaaca gccaccacca ctaaggcatt ccctaggtga ataaattggg ctccaactgg
      541 aatacgcagc agctcaaccg atataaaaat aagagcagca aataggctaa gctcgatctg
      601 atcagtcaat cgttttgatg tcatcttttt cctccaataa tcctctaaac gcggctccca
      661 agctgcccaa ttctacttcg taggcaattc caagtgaaag ctctcgattt agcgcaacag
      721 tagccgctaa tgacttgtct aagaagctaa taaccatatc caacaactca tcaatagcaa
      781 gcctgtgaaa atacccagcg ctaacaatag cagagacaag atcacctgtc ccatagaaat
      841 gataagggta ccgttttcca aaatgatagc taaccgtctc tgttgccttt tgataataag
      901 caaagccgat gtgctgatca tcaaaggata taccagtaag gacaatctct ctaggtccta
      961 gtgtagctag cttagacaat agcctctcca aatcctctct gctataggtc tccccaaaat
     1021 aaggaacatc agctaacaaa caagcttccg tcacatttgg caatatcagc tgtgcagctt
     1081 gagcgagcaa tctcattgcc gataagtgct gcgaggttaa ctgcgcatac atgcttccct
     1141 tgtcagccat aataggatct agcacaaagg gaagctgttg ctttttgatg taatcaagaa
     1201 taatcaaagc atcatcagga cggtacaaat aaccggaaaa aaagccatca aaggcaagac
     1261 ccgcttgaga ccaagtcgtc aaaaatggct ttagtccctc tgacgtgctc tgaatataag
     1321 gcgtcttagc aattgcagtg tggcttgata acaaacaggt tggaagaatg gcctgttcaa
     1381 tctggcaagc cgccataatg ggaatactag cagacagagc aaccttgcca actccgacaa
     1441 tatcatttgc aacaataaca cgttttaaca accaataagc tccttcattt ctttttttac
     1501 tattgtaaga aaatccttga tgagatacaa taaggataga tttcatctgt atggggacac
     1561 ttatgacaag taaatatcaa caaatcattg cagacctaga gttggccatg caatcaaacc
     1621 aattcaaaaa gggagagaaa ctcccttcta ttagacaatt aagtcaacag tatcactgca
     1681 gcaaggatac agtgcaaaga gcacttttag ccttacaata caagcgcctc atttatgcta
     1741 ttccaaaaag tggctattat gtgcttggta aaattgagga aaagcagcat tcctttgagc
     1801 taagccttga ggattataat cagttggcct atgaggactt tcggctctgt ctaaatgaag
     1861 ccctagacgg taaagattct gatttattta actactatca taaggctgag ggacttgagg
     1921 agctgcgaga ggctttgctg ccttatttgg ctgataatgg gatttacgct aacaaaaatc
     1981 agctgctaat tacctcgggt acacaacagg ccctttacat tttagctcaa atgagatttc
     2041 ccaatggccg ccatcacatt ctccttgaga caccgaccta tcaccgaatg gagcagctag
     2101 cgacttcctt aggcttaccc tatcaaacca ttgaacgtga tgtcaacggt atcaatcttc
     2161 atcagcttga aagcatcttt aaaaccggac aaatcgcttt tttctatact atttctcgat
     2221 tttcaaaccc tcttggcctc tcctacagca aaaaagaaaa ggaaagcatt gttcggctgg
     2281 cagagcaata ccaggtttac atcgtagagg acgattatct aggggacttt gcatcgcata
     2341 gtgagcttcc gctacactac tacgacactc aacaccgggt catttatctg aaatcatttt
     2401 caatgagcgt ctttcctgcc ctgcgcattg gagccttgct tttacctgat gatctcaagg
     2461 aaggcttttt gttacaaaag tcaatgattg accttgatac caacctgatc atgcaaaagg
     2521 cactagcatt atatttagca aatggtatgt ttcaaaaaaa cctaaagcaa atgaggcaat
     2581 ttttcaacaa tagagcgcat aacttactag attttctaca aaaacacctt cctaacctag
     2641 cttatcagct cactcctcaa gcactgatta ttcaattaga taaagcattc aatcgcaaaa
     2701 agcttcttaa accacaccac acccaaatca tctcaacaag aaaagcaagg tatatgcttc
     2761 taacaatcag tcctgatatg ccatctaagc tgctcgactt gttttcagtg acacatgaaa
     2821 agacccaaga atagctcatt gggtctcagt gtcacaaaaa tgtcaatagc tatttgattt
     2881 gctcgaatcg taaatgaaca ctaatgctat cgccgtaacc gtttctctcc aaatctcttt
     2941 ggagccggta agcaatataa tgctctgcaa tagtcatgta gcctgcgtca atcagacgat
     3001 tttcaacaag tgattgaatc atattaatcg tcggacgctc cgcctgcacc tcttctagat
     3061 caataacaac ctttttagtt acctgagcta gatgctgtct ccagctgtca tcaatcacat
     3121 aaactgttct tgctgccttg atcaaagcct gataaatctt atccggatca aagtctgcca
     3181 gctgaccgtc acgcttaata atttgcataa gagcgcctct tttcatttag tttcattgct
     3241 tacattcatt atgcaaatgt tttcatcatt tgtcaagcta ttaggctcct atgcctctta
     3301 gggattatca gtcaaaagaa acactaggat caaataaatt gtcctgtgct ggtcggacaa
     3361 gcccacgctc gtgcaaggtc tctgcaatct gaacagaatt ccaggctgcg cccttgagca
     3421 gattgtcaga taccacccac atgtgaatgc ccttttcaac atctaaatcc ttacgaagcc
     3481 ttcctacaaa ggtctcacga ctgccaacag cattaacggc ctgtgggtat cgttgcactc
     3541 cggtatcgtc ctctaaaaca gcacccggaa attgtgcaat cgcctcctta acagcttcga
     3601 tagtagctac tgccttggtt tcaatgtaga tagattctga atgggctgat aaaacgggta
     3661 tacgaacaca ggtcgcagac accttaatcg tatcgtcctc catgattttt ttcgtttcat
     3721 ttgtcatttt catctcttca taggtgtagt cattttcagt gaaacgatca atctgtggta
     3781 aagcattaaa agcaattgga taatgtctct tgtcaccagc tgacggtaaa acacttgcct
     3841 ccacctcctt aggagacaag ccctggttaa taacctggtc atactgagct agggtctcac
     3901 gaatcgctga ttgaccagca cctgaaacag cctgataggt ggaaacaata atacgctcaa
     3961 gaccccacct ttgacgaata ggctccagcg ctatcatcat ttgaatcgta gagcaattag
     4021 ggcaagcaac aaggccttga tgtgtatcaa gagcgtgagc atttacctca ggaacaacaa
     4081 gtggaacagc tgggtgctga cgaaaataag aggtattgtc aaccacaaca gcacctgccg
     4141 caacagcata aggggcatat tttgcagaaa cattgcctcc tgctgaaaaa agggctagat
     4201 caatgccttg gaaggctgct tttgttagct cctcaacaac aaaatcctct cccttaaatg
     4261 agaggatttt tcctgctgaa cgtgcagacg ctaataattt aatagctgaa ataggcagac
     4321 ttgactcctc cagcatctta atcatttgct gaccgacagc gcctgtcgct ccaaccactg
     4381 ctactgtata ccccatagat cgacctcact ttaactgatg atattgcaaa aaatgatatt
     4441 ggacctatta tagcctattt catcacaaaa gaaaagcaag ctagaagcca gaacaaacgc
     4501 atgaagaaaa tcatttattg aaaaagttgt gaaaatagca aaatatccat tttagagtat
     4561 tttgacagag tgtttcctga atttttatat ttttcctcta taaacttttc ttgaaaaa
//
LOCUS       DARYNN010000091         4437 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.092, whole genome shotgun sequence.
ACCESSION   DARYNN010000091 DARYNN010000000
VERSION     DARYNN010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4437
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.092"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            1..1167
                     /locus_tag="TVB59_001947"
     CDS             1..1167
                     /locus_tag="TVB59_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEL1010794.1"
                     /translation="MKYNKTKYPNIFTYDTKKGKRYYVRRGYYLKGKKKEATKSNLKT
                     LQEARAALTEIEQKIENNDFAYNKNLTVDQYWEIYVDNRLKAGVWSPDTYVERTNIFK
                     NHIGPKFGNKKMNAINRIEYENYINNLLNTNSRSTVKHIYDVFSIMLNHAVKNKMLDD
                     NIIKFIDIGDSEIKPINKRRSMQEFKAWDKIARKMLDDYDYAMVRITYLGLRRSEVAG
                     IKLGNITFNDKDCAVVKIDESRTRGRKDGGGLKTAYSERYVYLDFETSQLLKKAIDTS
                     IKIAVCNDRILNKADFLFLGDDEKVKPSFVGKPIGSHYIYCLFKKINKNCDVNFTPHM
                     MRHFFATQGQIAGVPIEHMAAALGHSNNYMTSQYTHIKDEVSENVTAAFMGSIK"
     gene            1316..2092
                     /gene="recX"
                     /locus_tag="TVB59_001948"
     CDS             1316..2092
                     /gene="recX"
                     /locus_tag="TVB59_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEL1010795.1"
                     /translation="MKISQIEKKKHLYLIKLDNGDSLTVTEDTIVTFMLSKHMVIDSQ
                     QWEDIKSFAQFSYGKSKALGFIAFQQRSQKQVQDYLLKHQISPDLIPSIIDSLKQGKW
                     IDDQQYVDTYIRQNSLTGDKGPLLLKQKLMLKGIASQLIEPVLAQTDFSSIAQKAAEK
                     IYQKYQHKLPSKALTDKIIQGLLNKGFSYDLAKGIVSQLSLEQDSQHIEDLLDQEFDK
                     LLRKYSRRYDGYQLKQKLYQALYRKGYDSDDITTKLNDYF"
     gene            2325..2858
                     /locus_tag="TVB59_001949"
     CDS             2325..2858
                     /locus_tag="TVB59_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002949762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEL1010796.1"
                     /translation="MKLPKEGDFITIQSYKHDGRLHRTWRDTMVLKTTENALIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGVSYYCNLASPYLMDAEALKYI
                     DYDLDVKVFADGEKRLLDVDEYEMHKQEMHYSPNLDFILKENVKLLVDWINKEKGPFS
                     KAYVSIWYKRYLELKNR"
     gene            3108..3419
                     /locus_tag="TVB59_001950"
     CDS             3108..3419
                     /locus_tag="TVB59_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEL1010797.1"
                     /translation="MAFQATKGRYASFGVAVSLPPELIDTFWEIIDHYLKGVFPLNTV
                     LTFRLIKNKKNLSYEYIDQQAGLRIVFDYNTPFNAFYPKTLYIVNQQGIETILLPHEM
                     Y"
BASE COUNT         1572 a          875 c          763 g         1227 t
ORIGIN      
        1 atgaaataca acaaaacaaa atacccaaat atctttacct acgatacaaa gaaaggtaaa
       61 cgctactacg tccgtagggg ttattactta aaaggtaaaa agaaagaggc tacaaaaagc
      121 aacttaaaaa cgctacagga agccagagct gcacttactg aaattgagca aaaaatagaa
      181 aacaatgatt ttgcttataa caaaaatttg acagttgatc agtactggga aatatacgtt
      241 gataatagat taaaagctgg agtgtggtct cctgacacat acgttgagcg cactaatatc
      301 tttaaaaatc acatcggccc aaagtttggc aataaaaaaa tgaatgctat aaaccgtata
      361 gaatacgaaa actacattaa caatctgctc aataccaact caagaagtac agtaaagcac
      421 atatatgatg tttttagtat tatgttaaat catgctgtca aaaataaaat gctagacgat
      481 aatatcatca aatttattga cattggcgat agcgaaataa aacctatcaa caaacgtaga
      541 tcaatgcaag agtttaaagc ttgggataaa attgccagaa aaatgcttga tgattatgac
      601 tacgcaatgg ttaggataac atatcttgga ttgcgtagaa gcgaggtagc tggcataaaa
      661 ttagggaata taacttttaa tgataaagat tgtgcagtcg taaagataga cgaatcaagg
      721 accagaggta gaaaagatgg cggaggccta aagacagctt attcggaacg atatgtgtat
      781 ttagatttcg agacatcaca actgctaaaa aaagccattg atacatctat caaaatagcc
      841 gtgtgcaacg atcgcatctt aaacaaggct gatttcctat ttttaggaga cgacgaaaaa
      901 gtaaagccat cttttgtagg aaaaccaatc ggtagccact acatctactg cttatttaaa
      961 aaaatcaata aaaattgcga cgttaatttt actccgcaca tgatgaggca ttttttcgct
     1021 acacagggcc aaatagccgg tgtcccaatt gagcatatgg cagcggcttt aggtcattca
     1081 aataattaca tgactagcca atacacccac ataaaagacg aggtaagtga aaatgtcaca
     1141 gcagctttta tgggcagtat aaaataaaaa ttccccgaca tagtccccga caaaatatta
     1201 ctttttatga tttttgttac tttttatgac taaacgaaaa aaactaaaat gctgtaatat
     1261 caacgtttta aaacaatttg cttgtatata aattttaaaa cattataatg agggtatgaa
     1321 aatcagtcaa attgaaaaga aaaagcattt atacctcatt aagctagaca atggtgatag
     1381 cctaacggtc acagaagata cgattgtcac atttatgcta agtaagcaca tggtcataga
     1441 cagccaacaa tgggaggaca tcaaaagctt cgcacaattc tcatatggta aaagcaaggc
     1501 cttaggtttt attgccttcc aacaaaggag ccaaaagcaa gtccaagatt acctgctaaa
     1561 gcatcagatt agtcctgatc tcattccaag cattattgat agcctaaaac aaggcaaatg
     1621 gattgatgat cagcaatacg ttgacaccta tatacgccaa aatagcctta ctggagacaa
     1681 gggaccatta cttctcaagc aaaagctaat gctcaaggga atagcctcac aactcattga
     1741 gcctgtccta gcacagactg atttttcctc tatagcacaa aaggctgctg aaaaaatcta
     1801 ccagaaatat caacacaaat tgccaagtaa ggccttgacc gataaaatca tacaaggact
     1861 tcttaacaag ggcttttcct atgaccttgc caaaggcatt gtcagtcaac taagccttga
     1921 gcaggatagt cagcacatcg aagacctgct tgatcaggaa ttcgacaagc tattacgaaa
     1981 atacagtcgt cgctatgatg gctatcagtt gaagcaaaag ctttaccaag ccctttaccg
     2041 caagggctat gacagtgatg atattaccac taagctaaat gactatttct aattctacca
     2101 aggctgctgc accgatttga cgcaaaagct tttagtcagc aacaaagtag tcctattatg
     2161 atcctgtagc tttgataatg gtttagctag ctcctcaact gaacatcaga tttctaaaaa
     2221 cttctttaag catttgtcag atcatattgt ccaaaacagt gatttatttt ctcaattatg
     2281 gtaaactata gaggataagt ttaattgtag aaagttggta aggcatgaaa ttacctaaag
     2341 aaggcgactt tattacaatt caaagttata agcatgatgg tagattgcac cgaacctggc
     2401 gcgatactat ggtactaaaa acaactgaaa atgctctgat tggagttaat gatcacacac
     2461 ttgttactga aagcgacggc aggcgatggg tgacacgaga gcctgcgatt gtttattttc
     2521 ataaaaaata ctggttcaat attatagcaa tgattcgaga taatggtgtt tcctattatt
     2581 gcaaccttgc aagtccatac ctgatggacg cagaagcgct caagtatatt gactatgatc
     2641 ttgatgtcaa agtctttgca gatggtgaaa agagattgct tgatgtagac gaatatgaaa
     2701 tgcacaagca agaaatgcat tattcaccta atctggattt tattttaaaa gagaatgtca
     2761 agctattagt cgactggatc aataaagaaa aaggaccatt ttcaaaagcc tatgtcagta
     2821 tttggtacaa acgttatctt gaactgaaga atcgttagtc gttgtctagc actccaccga
     2881 gggtgcttta tttaatcgct agtatagtat cacagctgta aactggactg gcacttgcaa
     2941 tctatcagca tttgttgtca aattcatatc attaaccact atagcttggc acaagcacag
     3001 acagcctata acaccaagta gcaatcagta tttatcatca gctgcctagc tagatcaggc
     3061 attcaaatga cctcattata acaccataac aatagaaagg attgacaatg gcatttcaag
     3121 caacaaaagg acgatacgca agctttggcg ttgcagtcag ccttccacct gagctgattg
     3181 ataccttctg ggaaatcatt gaccattacc taaaaggggt gtttcccctc aatactgttc
     3241 tcaccttcag gctaattaaa aataaaaaaa acctttctta tgagtacatt gatcaacaag
     3301 ctgggcttcg gattgttttt gactataaca caccatttaa cgccttttac cccaaaacgc
     3361 tctatatcgt aaaccagcaa ggaattgaaa cgattttatt gcctcacgag atgtattgat
     3421 aagacctcgg acatcagcta taaagtcctt accattcagt tgtagctcat cacatctgct
     3481 acaagcacca acatgagata atcttgtgtc tttatcctag ctctgaatgc tgtatagata
     3541 ttcagtcagc cagatacata gcaataaact aagctcatgc cggtagaaat agtcctaaca
     3601 tgagcttgac agttttttca ttctgtaaat cattgctaag caaacacatc acctaagccc
     3661 tatttcctat tctgggaaat ggaaatcttg atagaacatc ccaatagtcc catcatattg
     3721 agctatatct atagggtctg acattttgat atgttatcat ctcattttac gacaatcact
     3781 ataggcttta tgacaattgg catcattgtc ataacgatta aattctatat gaccaaatgg
     3841 ctagtaggaa gctaattgct ttgtgttagc ctcacatagg atcttcacat accccgtaat
     3901 cttaaaagta gttttaactg cacaaaactt atagaaccta aaaatcaaca aacacacttt
     3961 aaagtacaaa aactttgccc tccctcaaaa agctctataa tctctgtagt cggtaagccc
     4021 actgtggaaa ttatagtttt tttaattgta caaaaacaag cccatatgac ttatcatgaa
     4081 atgcaatcaa accatcatta gaaagactca taggaacacc ttaagcatta ctcagcattt
     4141 aaaaaacaat atccaaccgt tgactgttct aaaagctcac ccccacatcg ttatcaatcc
     4201 taagcttgat tattcagttc tcttatgccc tcactacaaa ggaaacatga gcaaacaaga
     4261 cttccaaaaa gcctctaaaa tccctatctt cgattgccaa agctttccaa cactgcttca
     4321 actcaaaaaa cactgctttc agtggaaagc cagttctaaa gtgagccttg ctcaaactcc
     4381 ttttggtttt aacatcacaa aaaagagcac caatctggtc ctctttagac gttagtt
//
LOCUS       DARYNN010000092         4294 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.093, whole genome shotgun sequence.
ACCESSION   DARYNN010000092 DARYNN010000000
VERSION     DARYNN010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4294
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.093"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            <1..1202
                     /locus_tag="TVB59_001951"
     CDS             <1..1202
                     /locus_tag="TVB59_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HEL1010798.1"
                     /translation="LGFSYVDMVRDMKSELNTNLEIYILGESEEYKNFSSLIENDCFY
                     KYPDVDYRSIGLLLLSGGTTGIPKLIPRRHCDYIYVAKKTTDRCNVNQESVYLASLPI
                     AHNFPLGCPGIMGTFAKGGKVVLCNVTSPDEILPLIEEEKVTITGFVPAIANICMDYL
                     EYEEYDLSSLEVIQVGGSVLEPWLAEKIEKVFDVKLQQIFGIAEGLILTTNEEDNDKI
                     RWQTQGKPISEHDEILIVDEQGKIVGIEEYGELIVRGPYTIYGYYNLPEVNETCITQD
                     CYFKTGDKARKLKDGNYQIVGRIKEIINRAGEKITPLELEEILLTHENINSVQVVGLP
                     DRLQGESIAVFILNGDKELTLEEVRKFLISNNVADFKLPDTVKYIDAWPLTALGKIDR
                     NKLKETF"
     gene            1217..>4294
                     /locus_tag="TVB59_001952"
     CDS             1217..>4294
                     /locus_tag="TVB59_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid adenylation domain-containing
                     protein"
                     /protein_id="HEL1010799.1"
                     /translation="MELNNIKERAKELVKDWLKSIFVEKVVSENENLIEKGLSSIQVM
                     QLSGKLKKTGIKISFAKLMEEPNLSKWYELIDKSRVKSDKNIESSIIQSDESKFDLTD
                     VQYSYLIGREDDQILGGVGCHAYLEIDGENIDEDKLKEAWNKLQYRHPMLRTKFTKDG
                     KQEILYKPYSEEIEVFDLSDLDEETLHLKLVEIREQKSHRKLNVNQGQVAGVALAKFS
                     DEKSRIFFDVDLLVSDVMSMSIMIKELAELYSGVELDNLNEYTFKDYMQNGIGESIND
                     ADKEFWEQKINSFEIERPNLPLRKQPEQIKETKFTRRKRIIKKSEWETIKDIAASYRS
                     TPSMVLLTAYALVLERWCNQDKFFINIPLFNRDLENENLKEMVADFTNILLVEHEAVD
                     DSNFLDNLKRINKTFLENVSHSEYNGVQVQRDISKKQGTSVYIAPVVFACNIDYPLET
                     EFSRKNLGKVSYMISQTPGVWLDFQTYIVDGDLILCWDSVDELFPTGMLEDMMDSLYE
                     LIISLTQKEEWEKKVDVLPEKQKSIRMQDVEGILPLQYPSETLYDGFLRNVKLNPDRV
                     AIIDSETKEEITYHKLYEISLKVADCLGKNGVKKGDYVGITLPRGSRQLYAIFGILFT
                     GAAYVSIGIAQPNDRRTKIYDQIGIKCIISDEKTVIDCKLNKNEVKIIDLDVAMANVA
                     KLKQPVEISPYDSAYIIMTSGTTGVPKGVEIMHTSAVNTCIDLNEKYNVNAEDTILMV
                     SAIDFDLSVYDIFGILHAGGTVITTSEDNYRNPDEWLNLVDEYKVTIWDSVPILFDMI
                     VTMAEGKNRNLPFRIVMLSGDWIAINLPERFYNISENINSIVVAMGGATEASIWSNHL
                     NVPRKIPKDWISIPYGRPLKNQVYRVVDEFGRICPNYVKGELLIGGVGVAKCYHGDEE
                     LTNKKYFEQDGMRWYRTGDNGRTWNDGIIEFLGRKDTQVKVKGHRIELGEIENALIVF
                     ENIKKAIALIVKDGNVNKLVGFAEIFDCKESNQMLLNSDFEKETEEYKKQKDEY"
BASE COUNT         1597 a          481 c          916 g         1300 t
ORIGIN      
        1 atttaggttt ttcatatgtg gatatggttc gggatatgaa atctgaatta aatacgaact
       61 tggagattta tattcttgga gaaagtgaag aatataaaaa tttttcgtca cttattgaga
      121 atgattgttt ctataaatat ccggatgtcg attacaggag cataggatta ttgttattat
      181 ctggcggtac aacaggaata ccgaaactga ttccaagaag acattgcgat tatatctatg
      241 ttgcaaagaa aacgacggac cggtgtaacg taaatcagga aagtgtatat cttgcttctt
      301 tgccaatagc tcataatttt cctttggggt gtccagggat aatgggtact tttgcaaaag
      361 gcggaaaggt ggttttgtgc aatgtgacaa gccctgatga aattttacct ttaattgagg
      421 aagaaaaggt tacgataaca ggatttgttc ctgcaattgc caatatttgt atggattatt
      481 tagagtatga agagtatgat ctttcctctt tggaggttat acaagtcgga ggttcagttt
      541 tggaaccttg gttggcagaa aaaattgaaa aagtttttga tgttaaacta caacagattt
      601 tcggaatcgc tgaaggattg atcttgacaa caaatgaaga agataacgat aaaataagat
      661 ggcaaacaca aggcaaacca atcagtgaac atgatgaaat actgattgtg gatgaacaag
      721 gaaaaattgt agggattgaa gaatatggag aacttatcgt tagaggtcct tataccattt
      781 atggttatta taatcttcct gaagtaaatg aaacatgtat aacacaagat tgttatttta
      841 agactggtga taaagcacga aaactaaaag atggtaatta tcaaattgtc ggaaggatca
      901 aagaaatcat caatagagca ggtgaaaaga taacaccact tgaattagaa gaaattttgc
      961 ttactcatga aaatatcaac tcggtacaag ttgtagggct gccagatcgt ctgcaaggag
     1021 aatccattgc tgtatttatt ttaaatggag ataaggagct tacactggaa gaagttagaa
     1081 aattcttgat ttctaataat gtggcggatt ttaaattgcc ggatactgtt aaatatattg
     1141 atgcgtggcc attaacagct ttagggaaaa tagatagaaa taaattaaaa gaaacttttt
     1201 aaaggaggat tttggaatgg aacttaacaa tataaaagaa agagctaaag aattagtaaa
     1261 ggattggttg aaaagtatat ttgtagagaa agtagtttca gaaaatgaaa atttaattga
     1321 aaaaggttta agttccattc aagtcatgca actgtctgga aaattaaaga aaacggggat
     1381 aaaaatttcg tttgcaaaac ttatggaaga accgaatttg tccaagtggt atgaacttat
     1441 tgataaatcc agagtgaaaa gtgataagaa tatagagtca tcaattatcc aaagtgatga
     1501 aagtaagttt gatttaacag atgtccagta ctcctattta atcggaagag aagatgatca
     1561 gattttaggt ggcgtgggtt gccatgcata tcttgaaata gatggagaaa atattgatga
     1621 ggataagtta aaagaggctt ggaataagct tcaatacaga catcccatgc ttagaacaaa
     1681 atttacgaaa gacgggaagc aggaaatatt atacaaaccg tacagtgaag aaatagaagt
     1741 ttttgattta tctgatcttg atgaagaaac gctgcatcta aaattagtag aaattagaga
     1801 acaaaaatct cataggaaat taaatgtaaa tcaaggtcag gttgcaggag tagcactagc
     1861 aaaattttca gatgagaagt caaggatatt ttttgacgta gatttgcttg tatccgatgt
     1921 aatgagcatg agtattatga ttaaagaatt agctgaactt tattcaggag tagaacttga
     1981 taatttgaat gagtatacgt ttaaggatta tatgcaaaac ggaattggcg aatcaatcaa
     2041 tgatgcagat aaggagtttt gggaacaaaa aataaattcc tttgaaatag aaagaccgaa
     2101 cttaccatta aggaaacagc cggaacaaat taaagaaacg aagtttacaa gaagaaagag
     2161 aattattaaa aaaagtgaat gggaaaccat aaaagatata gcagcatcgt atcgaagtac
     2221 accatctatg gttcttctaa ctgcctatgc tcttgttctt gaaagatggt gtaatcagga
     2281 taaatttttt atcaatatac cgctatttaa tagagattta gaaaatgaaa atctaaaaga
     2341 aatggttgct gattttacaa atattttatt ggtagagcat gaggctgtag atgattcaaa
     2401 ttttttagat aatttaaaga gaataaataa gacattcttg gaaaatgtat ctcacagtga
     2461 gtataacgga gtgcaggttc aaagagatat atcaaaaaaa caaggtacaa gtgtgtatat
     2521 agcacctgtg gtttttgcgt gtaatataga ttatccattg gaaactgaat tttcaagaaa
     2581 aaatttaggg aaagtatctt atatgatttc tcaaacacca ggagtttggc ttgattttca
     2641 aacatatatt gtagatggag atttaattct ttgctgggat agcgtggatg aactttttcc
     2701 aacaggaatg ttagaagaca tgatggattc tttatatgaa ttgatcatat ctttaacaca
     2761 gaaggaagaa tgggaaaaga aagtagatgt tttacctgaa aagcaaaagt ctattagaat
     2821 gcaggatgtt gagggaattt taccacttca atatcctagc gaaacgttat atgacggatt
     2881 tctcagaaat gtaaaactca atccagatag agttgcgatt atagattctg aaacgaagga
     2941 agagataaca tatcataaac tttatgaaat ctctttaaaa gttgcggatt gtttaggtaa
     3001 aaatggtgtt aaaaagggag attatgtagg aataacactt ccaagaggta gcagacaact
     3061 ttatgctatt tttgggattt tatttaccgg tgcagcatat gtatcaattg gtattgctca
     3121 gccaaatgat agaagaacta aaatttatga tcaaatcgga ataaagtgca ttataagtga
     3181 tgaaaagaca gtgatagatt gtaaattaaa taaaaatgaa gttaaaatta ttgatttgga
     3241 tgtagctatg gcaaatgtgg ctaaattaaa gcaacctgtt gaaattagcc cttatgatag
     3301 tgcgtatatt attatgacgt ctggaacaac aggtgttcct aagggtgttg agattatgca
     3361 tacaagtgcc gttaatactt gcattgattt aaatgaaaaa tacaatgtaa atgctgaaga
     3421 tacaatactg atggtgtcgg caatagactt tgatttgtcg gtttatgata tttttggaat
     3481 acttcatgct ggaggaacgg ttattacaac aagtgaagat aattatagaa atcctgatga
     3541 atggttaaat ttagtcgatg aatataaggt tacaatatgg gattctgtgc cgattttgtt
     3601 tgatatgatt gttactatgg ctgaaggtaa aaatagaaac ttacctttta gaattgtgat
     3661 gctttcaggg gattggattg ctataaattt accagaaaga ttctataata ttagtgaaaa
     3721 tataaattct attgttgtcg ctatgggtgg agccacagaa gcatctattt ggtcaaacca
     3781 tttgaatgta ccaagaaaaa taccgaaaga ttggatttcc attccatatg gtagaccttt
     3841 gaaaaatcaa gtgtatagag ttgtggatga atttggtagg atctgcccta attatgttaa
     3901 aggtgaactt cttatcggtg gagttggtgt tgctaaatgt tatcatggtg acgaagaatt
     3961 aacgaataaa aagtacttcg aacaagatgg gatgaggtgg tatagaactg gagataatgg
     4021 tagaacatgg aatgatggga ttattgagtt tcttggaaga aaagatactc aggtaaaagt
     4081 taaaggacat agaatagaac ttggagaaat agagaatgct ttaattgtat ttgaaaatat
     4141 aaaaaaagcg atcgctttaa ttgttaaaga tggaaatgtt aataaacttg taggatttgc
     4201 ggaaatattt gattgcaaag aaagtaatca aatgttattg aattcagatt ttgaaaagga
     4261 gactgaagaa tataaaaaac agaaggatga atat
//
LOCUS       DARYNN010000093         4186 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.094, whole genome shotgun sequence.
ACCESSION   DARYNN010000093 DARYNN010000000
VERSION     DARYNN010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4186)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4186)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4186
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.094"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            14..1363
                     /gene="gdhA"
                     /locus_tag="TVB59_001953"
     CDS             14..1363
                     /gene="gdhA"
                     /locus_tag="TVB59_001953"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEL1010800.1"
                     /translation="MVSAKDYVASVFDKVKRDNPHETEFLQAVKEVFDSLIPVFEKYP
                     NYIEENLLERLVEPERVISFRVPWVDDQGRVQVNRGYRVQFSSAIGPYKGGLRFHPSV
                     NQSIVKFLGFEQIFKNALTGQPIGGGKGGSNFDPKGKSDLEIMRFTQSFMTELQRHIG
                     PDLDVPAGDIGVGAREIGYLFGQYKRLNGFKNGVLTGKGLAYGGSLARTEATGYGVVY
                     FAQQMLAAKGQDLAGKTAIVSGSGNVAIYATEKLQALGVKVLAVSDSSGYVYDDKGID
                     LETLKQIKEVKRERIKTYLESHPAAVFTPAGEGSIWTIKADLAFPCATQNELQEADAK
                     ALIEHGVKAVVEGANMPSTLEAIEQFQQAGVLFGPAKAANAGGVAVSALEMAQNSGRT
                     AWTFEEVDHRLYDIMKAIYQKAAAAAKECGQEGNLVVGANIAGFLKVAQAMSAQGIV"
     gene            1495..1905
                     /locus_tag="TVB59_001954"
     CDS             1495..1905
                     /locus_tag="TVB59_001954"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEL1010801.1"
                     /translation="MIKKIVKDTFFLQQKAQPATKKDLWIGQDLQDTLAYYRDSCLGL
                     AANMIGENKRVIIISMGFVDLVMFNPVLIAKREAFEAEESCLSLIGQRKTKRYQEIKV
                     DYLDAHWHKKSLRLTGLPAQICQHELDHLEGILI"
     gene            complement(2096..4102)
                     /locus_tag="TVB59_001955"
     CDS             complement(2096..4102)
                     /locus_tag="TVB59_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase C-terminal domain-containing
                     protein"
                     /protein_id="HEL1010802.1"
                     /translation="MKKHFVLKSSVLGVFAGVSMLVTGVQADQVDVQFLGVNDFHGAL
                     DTTGSAYMPEGKVSNAGTAAQLAAYLDDAEADFKQTSPDGTSIRVQPGDMVGASPANS
                     GLLQDEPTVKVFNQMGFEYGTLGNHEFDEGLAEFNRIMTGTAPAEDSAINDITKQYEH
                     EASNQTLVIANVVDKETNTIPFGWKPYAVKEVPVNDKSVKVGFIGVVTTEIPNLVLKQ
                     NYEQYDYLDSAETIVKYAKELQEQQVNAIVVLAHIPATSDNGVVHDEMAAVMEKVNQL
                     YPEHSVDIVFAGHNHQYTNGTIGTTRVVQAVSQGKAYADVRGTLDTDLNDFVATPEAK
                     VIAVAPGIKTGNADIQAIVDQANDIVKTVTELKIGTAATSSTISKTENEDKESPVGNL
                     ITTAQLTIGRKTFPHVDFAMTNNGGIRADLVVKEDQTITWGAAQAVQPFGNILQVVQM
                     TGQQIYDVLNQQYDEDQKYFLQMSGLKYTYTANEANDPSTPFKVVKAYKDNGEEIDPA
                     AQYTLIINDFLYGGGDGFSVFKDAKLLGAINPDTEVFIEYIKDLEAAGKTVSAGINGV
                     KTYVTASLEGSTQSDHTGKHEIINRVFKNREGKVLATELVSDLFTPAQNANPATSIKP
                     LAAKKQANAALPATGTSQHSAAAMTILGLLTLTGTSLFKKKEGQ"
BASE COUNT         1135 a          831 c         1012 g         1208 t
ORIGIN      
        1 gagaggatat ataatggtat cagcaaaaga ctatgtagcc agtgtttttg ataaggtcaa
       61 aagggataat ccgcatgaga ctgaatttct tcaggcggtc aaggaggtat ttgattcctt
      121 gattcctgtt tttgaaaaat accctaatta tattgaggaa aatctattag agcgcttggt
      181 tgagcctgag cgtgtgattt cctttagggt gccttgggtt gatgaccagg gcagggtcca
      241 agttaatcgt ggctaccgcg tgcaattttc atcagctatc ggtccatata agggagggct
      301 tcgctttcac ccttctgtta accagtctat agttaaattt cttggctttg agcagatttt
      361 caaaaatgct ctgactggtc agcctattgg aggaggaaaa ggaggatcaa attttgatcc
      421 taaaggcaaa tcagacctag aaatcatgcg cttcacacaa agctttatga cagagctgca
      481 aaggcatatt ggacctgacc ttgatgttcc tgctggtgat attggtgtag gggctcgcga
      541 aattggctat ttatttgggc aatataagcg tcttaatggc tttaagaatg gtgtgttgac
      601 aggaaaaggc ttagcttatg gtggctcttt ggctcgcaca gaggccacag gctatggtgt
      661 ggtttatttt gctcagcaaa tgctggcggc taaggggcag gacttggctg gtaaaacagc
      721 tattgtatct ggatcaggaa atgttgccat ttacgcaacg gaaaaattgc aggccttagg
      781 tgttaaggta ttagcagtgt cggattcctc tggttacgtt tatgatgata agggcattga
      841 tcttgagacc ctaaagcaaa tcaaggaagt gaagcgtgag cgtatcaaga cctatctaga
      901 gagtcacccg gctgctgtgt ttacaccggc tggtgaggga tccatctgga ctattaaggc
      961 agaccttgcc tttccatgtg cgactcaaaa tgagctacaa gaggcagatg ctaaagcctt
     1021 gattgagcat ggggttaaag ctgttgtcga aggggctaac atgccctcaa ccttagaggc
     1081 tattgagcaa tttcagcagg ctggggttct ttttggacct gctaaagcag caaatgctgg
     1141 cggtgtagca gtttctgcgc tggaaatggc acaaaatagc ggacgtaccg catggacctt
     1201 tgaagaggtg gatcatcgat tgtatgacat catgaaggct atttatcaaa aagcagccgc
     1261 tgccgccaag gaatgtggtc aagaaggcaa cctagtggtg ggagctaata ttgcaggctt
     1321 tctcaaagtt gctcaggcca tgtcagcaca gggaatcgtt taagagctgt ggctggtata
     1381 tgctgaatat atcagtaggg ttagcacatt aatcttagct caatgacgtt aagatatacg
     1441 atcggtcatc tagacaatgc atgccgatta gagcaatgaa tcaaggagaa gctgatgatc
     1501 aaaaaaatcg tgaaggacac ctttttcttg cagcaaaaag cacagccagc aacgaaaaag
     1561 gacctttgga ttggtcaaga cctgcaggat accttagctt attatcgtga tagctgcctg
     1621 gggctggctg ctaatatgat aggggaaaac aagagggtta ttattattag catgggcttt
     1681 gtggatttgg tgatgtttaa tcctgtatta attgctaagc gtgaagcgtt tgaggcagag
     1741 gaatcctgcc tatcactaat cggccaacgt aagacaaagc gttatcagga gatcaaggtt
     1801 gattaccttg atgcacattg gcacaagaaa tccctgagat tgacaggcct gcctgcacaa
     1861 atctgccagc atgagctgga tcatctggag ggcatattga tttaaatcat gaccacccgt
     1921 tagtgaactg caccccaaaa gttagacaga aaatctaacg aatgagggca gtccatagat
     1981 gggtggttta tttgtcttgc tcaacaggtg cgaaacaaat aaacgtcaca taaatcagaa
     2041 aaccggctgt atgcttaaga tacagtcggt tattgctgtt atggctagga cgattttatt
     2101 ggccttcctt tttcttgaaa aggctagtac cagttaaggt tagtagtcct aggattgtca
     2161 tggcagcagc agaatgctgg cttgttcctg ttgctggtaa ggcagcatta gcttgctttt
     2221 tagctgctag aggcttgatg cttgtggcag gattagcatt ttgagcaggc gtaaataggt
     2281 cagagacaag ctcagtagca agcaccttgc cctcacgatt cttaaagacg cggttgatga
     2341 tctcgtgctt gccggtatga tcactttgag tagagccttc aagactggca gtgacatagg
     2401 ttttcacacc gttaatacca gcacttacag tctttccagc tgcttcaagg tccttgatgt
     2461 attcgataaa gacctcagta tcaggattaa tggctcctag tagcttagcg tccttaaaga
     2521 cggagaagcc atcaccaccg ccatatagga agtcgttgat gattagggtg tattgagctg
     2581 ctggatcaat ttcttcacca ttatctttat aagcctttac taccttaaac ggtgttgaag
     2641 gatcgttagc ctcattagct gtataagtgt atttgagtcc agacatttga aggaagtatt
     2701 tttggtcttc atcgtattgt tggttcaaga catcatagat ttgttggcca gtcatttgaa
     2761 cgacctgaag aatattgcca aatggttgaa cagcctgtgc agctccccag gtaatggttt
     2821 gatcctcttt gaccaccaag tcagcgcgaa taccgccatt atttgtcatg gcaaaatcaa
     2881 catgagggaa ggtttttcta ccaatggtta attgggcagt tgttatcaaa ttgccaacag
     2941 gagattcctt gtcttcgttt tctgttttag aaatcgttga agaggtagct gctgtaccga
     3001 tctttagctc ggtaacggtt ttgacaatgt cattggcttg atcaacaatg gcttgaatgt
     3061 cggcattgcc tgtttttatg ccaggagcaa cggcaatgac ctttgcttca ggagtggcta
     3121 caaaatcatt gaggtcagtg tctagtgttc cacgaacatc tgcataggct ttcccctgtg
     3181 aaacagcctg aacgacacgt gttgtgccaa tggtaccgtt ggtgtattgg tggttgtgac
     3241 cagcaaagac aatatccaca ctatgctcag gataaagctg gttaaccttt tccataactg
     3301 ctgccatctc atcatgaact accccgttat cacttgttgc tgggatatga gctaggacaa
     3361 caatcgcatt gacctgctgc tcttggagct ctttagcata tttaacgatg gtttctgcag
     3421 agtctaggta atcatattgt tcataatttt gttttaggac aaggtttgga atttctgttg
     3481 tcacaacacc gataaagccc accttgactg acttatcatt aactgggact tctttgacag
     3541 cataaggctt ccagccaaaa ggaatcgtgt tggtctcctt gtcaacgaca tttgcaatga
     3601 caagggtttg atttgaagct tcatgctcgt attgcttagt aatgtcgttg atagctgagt
     3661 cttcagcagg tgcagtgcct gtcatgatac ggttgaattc agctaagccc tcatcgaatt
     3721 cgtgattccc aagggttccg tattcaaagc ccatctggtt gaatacctta accgttggct
     3781 cgtcctgtaa tagtccagaa ttagcaggac tagctccgac catatctcct ggttgaacac
     3841 gaatgcttgt cccatctggg cttgtttgct taaagtcagc ctctgcatcg tccagataag
     3901 cagctaattg tgctgcggta ccagcgttag atacctttcc ttctggcatg taggcagagc
     3961 cggttgtgtc taaggcacca tgaaagtcat tgacaccaag aaattgcacg tctacctgat
     4021 cggcctgcac gccggttact agcatagaaa ctccggcaaa gacaccaaga acactacttt
     4081 ttaaaacaaa atgctttttc ataaacgctc ctaaaagttt aaagtattgt cacaagttaa
     4141 gtgtactatt atttaaatga gaattcaaca aaaattaata aaaaag
//
LOCUS       DARYNN010000094         4069 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.095, whole genome shotgun sequence.
ACCESSION   DARYNN010000094 DARYNN010000000
VERSION     DARYNN010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4069)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4069)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4069
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.095"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            295..2097
                     /locus_tag="TVB59_001956"
     CDS             295..2097
                     /locus_tag="TVB59_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HEL1010803.1"
                     /translation="MEVRGAMGNRQMKLKKYFLRFLLLLFAAIYIYFSSFAYQHSYLG
                     ISADYVNHSWVVSNIHNGGEASSSGLAVGDKILEIDHKSSQDNPLLNKLLIVEQATSM
                     TVLHQGIQRQIVFQKTHGSKKIFLMFSLLSIILFALSYGYSRRHEISRTSQRYYIFTF
                     LTSLLLVSIIPSSMGNVVARLILVIYITLFPFFIDMFWRAGTLQQESVKFSKFSKLII
                     TYSAATLCLLLYSKWFSVPLVITIYLVRGIFYVSFTFLVALFLITLVKDIKNNAFPRL
                     NIVLLVILCLLPLFIGYVFPLPYDIPFMYTIPLLLLPILAIINNLIINRLTTFRFHLP
                     VPILYVFIAMLGTVMIICLYLISDFMPKWLMISYSFLLTLCSIPIVKDLIFLNIRTGY
                     QLSNKSIFLAVEAEREDISIYLHDTIIQDIIYYKKRLENMDAVSKKAASDILDDVIFE
                     LRELCSNIYPLMIQELGLKNAILDIISKFQKKESVIINDNIQVEQLDFGQPINNFILR
                     SIRELINNSILHGNAKEIDIHIYNAEQYVVIKIVDGGHFKTARQTEAPHFGLTVIAEK
                     LALLGGQLLVDKHPTTIVMLIPRKQVNYDKNSNH"
     gene            2075..2674
                     /locus_tag="TVB59_001957"
     CDS             2075..2674
                     /locus_tag="TVB59_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1010804.1"
                     /translation="MIKIAIIDDHELVLQGLYDRLKKETHFEVVGAFTSYQDLLFCLK
                     YKSVDVLIIDLMLKDIHGFDLIAQIQQKCQTVPKMILISGFYEPLLHKRALDLGIKAF
                     LPKECSYDELISTVYNVAKGNQVIPDDLLQREESHLLTESEIEILKLISDEYSNEKIS
                     KKLYISRRTVDTHVSNICAKLNVTSRVGAVREAIRLKLI"
     gene            2782..3708
                     /locus_tag="TVB59_001958"
     CDS             2782..3708
                     /locus_tag="TVB59_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="avirulence protein"
                     /protein_id="HEL1010805.1"
                     /translation="MVDVDTLLGDHKTRYFGDGHKRTSYSINHDQNNQAYGTITQSGV
                     WSNKSDKVIQPHLSTLDGIVLASLAAERYLKEQYEACEDFYLSQFSVKSGRKPIEDLN
                     RVPIVVQKSSFNGDKASFSVSVLDMTVNLVFKRIDTYTAKDNKPAAEAKDYLSNHLKD
                     IHHHIYDVNFLDALDIADKCSIFCKANKAIRHVSNYKGISSQLSSSYSLLELLIIFSQ
                     MAEMLAYYADDIDRRYSETLWMKNVSAELVEPIPDGELALLGKITKNKLLDMKGKDWK
                     LFEMSGTDTQNRVRISSKIAHQLPSSEMLNNA"
     gene            3701..>4069
                     /locus_tag="TVB59_001959"
     CDS             3701..>4069
                     /locus_tag="TVB59_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEL1010806.1"
                     /translation="MLNKEIRLVISGTYSTGKTTTATALSIATGIPLINALSAREILT
                     DLYPGRRFQDMNATELMALGLKRFEERVREEAILYLQHTNFISDGSVLNEWIYGTVRM
                     KVGLNPGSGFIHRAAKAILGL"
BASE COUNT         1256 a          754 c          786 g         1273 t
ORIGIN      
        1 gcctgtgccc taaccctctc acctagacgc aaaaagaatc aaaacaaccg ttaataggaa
       61 atcatgaaag ccttctatga cagtcattgt tcataggagg ttttttacac caaatagacc
      121 ttctattggc ttttcatttg attcttaatg gatttttact gctaatttct gactcaccat
      181 cgttgcattc gtctcattat ttacaaattt atttggctaa tattgaaaat atgttatgat
      241 taatgtatta ttttggtatt atttttaaaa aatattattt tagaatggta aaaaatggag
      301 gtgagaggag caatgggtaa ccgtcaaatg aagctgaaaa aatacttcct caggttttta
      361 ttgttattat ttgctgcaat ctacatttat ttttcctctt ttgcctatca gcattcctac
      421 cttgggataa gtgctgatta tgttaatcat agctgggttg tcagcaatat ccataatggc
      481 ggggaggcta gctcctcagg actagctgtt ggggataaga ttttagagat agaccataaa
      541 agcagccagg acaatccttt gttaaataag ctgttaattg ttgagcaagc aacctcaatg
      601 actgttttgc accaaggcat acaaagacag attgtatttc aaaaaacaca tgggtctaaa
      661 aagatatttt taatgtttag cctgttatcc attatcttat ttgccttatc ctatggctat
      721 tctagaaggc atgagatcag tcggaccagt cagaggtatt acatctttac ctttttaaca
      781 tcgttattac tggtttcgat tattccatca agcatgggaa atgttgttgc ccgcttgatt
      841 ttagtgattt acatcacttt gtttcccttt tttattgata tgttttggag agcaggtaca
      901 ttgcaacagg aatctgttaa attttcaaaa ttttcaaaac tgatcatcac ctattctgct
      961 gcaaccctct gcttattgct atattctaag tggttttcgg tcccactcgt cattaccatt
     1021 tatttggttc gaggaatttt ctatgttagc tttacctttt tagtggcttt atttttaatc
     1081 accttggtta aagatatcaa aaacaatgct tttccaagac tcaatattgt cctgttggtt
     1141 atcctgtgct tgctgccatt gtttatcggc tatgtgtttc ctttgcctta cgatatccct
     1201 tttatgtaca cgatacccct attgctgctg ccgattttgg cgatcattaa taacctaatc
     1261 attaacaggc tcacgacctt tcgctttcat ttgccagttc caatcctcta tgtgttcatt
     1321 gctatgctag gcactgtgat gatcatttgc ttgtatctca tatcagactt tatgcctaag
     1381 tggttaatga ttagttatag ctttttacta accctgtgct caataccaat cgtaaaagac
     1441 ctgatttttt taaatatcag aacaggctac cagctgagca acaagtctat tttcctagca
     1501 gttgaggctg aaagagagga tatttcgatc tacctgcatg atacgatcat acaagacatt
     1561 atttattaca aaaaaaggct ggaaaatatg gacgccgtct caaaaaaggc tgcttcagat
     1621 attcttgatg atgtaatctt tgaattaaga gagctgtgct caaatattta tcccttgatg
     1681 attcaagagc taggcttaaa gaatgctatt ttagacatta tctctaaatt tcaaaaaaaa
     1741 gaatcggtga ttatcaacga caatatccaa gtggaacagc ttgattttgg gcagcccatt
     1801 aataatttta tcctcagatc aatacgagag ctgattaata atagcattct tcatggtaat
     1861 gctaaggaaa tagatataca catctacaat gctgagcaat acgttgtgat caagattgtt
     1921 gatggcggac attttaagac tgctcgtcag acagaagcgc ctcactttgg cttaactgtt
     1981 atcgctgaaa agttagcatt gctgggtggt caattgcttg ttgacaaaca ccctacgact
     2041 attgtcatgc tcattcctag aaagcaggtg aattatgata aaaatagcaa tcattgacga
     2101 ccacgaattg gtcttacaag gcctatatga tcggttaaaa aaggaaacac attttgaggt
     2161 tgtcggcgct tttaccagct accaagattt gttattttgc ttgaaatata agtctgttga
     2221 cgttttgatt attgatctca tgctaaagga tattcatggc tttgacttaa ttgcacaaat
     2281 ccagcagaaa tgtcagaccg tgccaaaaat gattttaatt tcaggatttt atgagccctt
     2341 gctgcacaaa agagccttgg atctaggcat aaaggccttt cttccaaagg aatgctccta
     2401 cgacgaatta attagcactg tctacaatgt tgcaaaggga aatcaagtga ttccagatga
     2461 cttgctgcag agggaagaaa gtcatctgct aaccgagtca gaaattgaga tattgaaatt
     2521 aatctcagat gaatactcga acgaaaaaat ctccaaaaag ctctatatca gcagaaggac
     2581 tgttgatacc catgtttcaa atatatgtgc taagctcaat gtaacaagcc gagttggagc
     2641 ggtgcgggag gctatcaggc tgaagctgat ctaacaagtc aaccaaaaaa ggcagacaga
     2701 tattcgtaaa ttacggatgt ctgttttttg atagtgtttt atcataagcc ttggttataa
     2761 ataagaaaag gagagaaact aatggttgat gtcgatacat tacttggtga ccacaaaaca
     2821 aggtattttg gtgatggtca caaaagaaca agctacagta taaatcatga ccaaaataac
     2881 caagcttacg gaacaattac ccaatcgggt gtgtggtcaa ataaatctga taaggtgatt
     2941 cagccacacc taagcacctt agatggcatt gttctagcca gtctagcagc tgaaagatat
     3001 ctaaaagagc aatatgaagc atgtgaagat ttttatttat ctcagttttc ggtcaaatca
     3061 ggcaggaagc ctattgaaga tttaaacagg gttccaattg ttgtccaaaa aagctctttc
     3121 aatggggata aggcaagctt ttcggtgtca gtgctggata tgactgttaa tctagtattt
     3181 aaacgcattg acacctatac agcaaaagac aacaaaccag ctgcagaggc aaaggattac
     3241 ttgtcaaatc atctaaagga cattcaccat catatctacg atgttaactt tttagacgca
     3301 ttagatatag cagataagtg ctctattttt tgtaaggcta ataaggcaat ccgccacgtc
     3361 agcaattata agggcatatc ctctcagcta tcaagcagct attccttatt agagctcttg
     3421 attattttct cacagatggc tgaaatgttg gcatattatg ctgatgatat tgatagaaga
     3481 tacagtgaaa ccttgtggat gaaaaatgta tcagccgagc tcgttgaacc gatacctgat
     3541 ggtgagctgg cccttttagg taaaattacc aaaaacaaat tacttgatat gaagggcaag
     3601 gactggaagc tgtttgaaat gtcaggtact gacacacaaa atcgagtgag aatttcaagt
     3661 aaaatagccc atcaattacc tagttcggag atgcttaaca atgcttaata aagaaattag
     3721 acttgtcata tcaggcacct attctactgg taagacaaca acagcaacgg ctctgtctat
     3781 tgcgacaggc atacctttga ttaatgcact ttcagccaga gagatcctga ccgacctgta
     3841 tccaggcaga cgctttcagg acatgaatgc cactgagcta atggctctag gattaaaaag
     3901 atttgaggag cgggtgcgcg aggaagccat tttatacctc cagcatacca actttatctc
     3961 agatggctcc gtgctaaatg aatggatcta tggaacagta cgaatgaagg taggcttaaa
     4021 tccgggctct ggcttcattc atcgagctgc aaaggccatc cttggactt
//
LOCUS       DARYNN010000095         3858 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.096, whole genome shotgun sequence.
ACCESSION   DARYNN010000095 DARYNN010000000
VERSION     DARYNN010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3858)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3858)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3858
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.096"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            <1..420
                     /locus_tag="TVB59_001960"
     CDS             <1..420
                     /locus_tag="TVB59_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1010807.1"
                     /translation="GRNIAEINSESLYKKIAFVQKNDFLVEGNVSDNIKLDGSLNLTD
                     KLKDSLGFDETFLNKKLFRVQSLISEGEKQRIDLARFLNRRYSIYIFDEPTGNLDPAR
                     SKAILDYILSIKNAIIIVITHNQDIKTLEQFDEVICL"
     gene            583..1705
                     /locus_tag="TVB59_001961"
                     /pseudo
     CDS             583..1705
                     /locus_tag="TVB59_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000371017.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
     gene            1698..2873
                     /locus_tag="TVB59_001962"
     CDS             1698..2873
                     /locus_tag="TVB59_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEL1010808.1"
                     /translation="MNKKIIFKGDQDSKFAYFSLMFSAGTAIENTEELGFSHLIEHLL
                     LRSGGEQSLNELFDNNGAFIGGETSRDYINLMGYCKAENFKNIFEAIVSRVFNLNLTE
                     EELLREKRVVLVELTQYENGSKTEKLVSDNRLIFKNSKWSEDIIGVRENIESVDLKKL
                     YKFYTENIQNGEFQIAISGPNHLKEEIAIIENKLPVGRTPVKSNFPIFSSGVTERKKN
                     QQVSEISMYIDISKMTTSSHDVAILTILNAMLTGVKGSVLGGKLRTKNQWVYNIISFP
                     IFYNGLTILKILTRTPEIHKHQVVQVLKEDLVNREDLKNTKLFDKAKKRVINEVLMSY
                     EVKKVEFLKTLCREKLFNIPSWESVTGEIEKVSLNELNQFAKDALMQNKQFHIIINC"
     gene            complement(2857..3720)
                     /locus_tag="TVB59_001963"
     CDS             complement(2857..3720)
                     /locus_tag="TVB59_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000600261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1010809.1"
                     /translation="MILGETYRKMREEKGISISSLAGYEISKSQISRFELGETEISIF
                     KLLYLLEKLGITFEEFLLACNNYEPSEFNTLIKAVQNSAYNNKVETLISMIEQENKLF
                     EETNSHYHKLNSIFIQSIISGLDNNHQLTNQDISYLSNYLFSLENWGYYETLILGNCC
                     RSLPPKLLFKYTKEALKKGKLYNSIPRNKQSLIQLLLNSLLLMIENDFYEEAIFLNQA
                     SKNLLSNSTYFFELTILLYLEGYLELKFNIHTEKSNSKIEEALKIFNSLNKTIYQNYQ
                     EHFNKYISNLL"
BASE COUNT         1431 a          425 c          683 g         1319 t
ORIGIN      
        1 ggaagaaata ttgctgaaat taactcagaa agtttgtata agaagattgc gtttgttcaa
       61 aaaaatgatt ttcttgtgga aggtaatgtt tcagacaata ttaaattaga tgggagtttg
      121 aatctaacag acaagctcaa agatagttta ggatttgatg aaacattttt aaacaaaaaa
      181 ttatttagag ttcagtcttt aatctcagaa ggagaaaaac aaagaattga tttagcaaga
      241 tttttaaacc gtagatattc tatttatatt tttgatgaac caactggtaa tcttgatcca
      301 gctagatcta aagccatatt ggattatatt ttatcaataa agaatgcaat catcattgtg
      361 attactcaca accaagatat aaaaacgtta gaacaattcg atgaagtcat ttgtttgtaa
      421 atgaaagggg gtgatgaaca tgattatgga agattttgaa gttttagaac tagagtttgt
      481 cgaagttcga aatgaacaaa ccacaaattg gtattttgtt taatcacaaa ggcatgcaat
      541 gagaatttgc atgcctttgt aaaatataga aaggacaata aaatgaataa tttttttcca
      601 aaatggaatc aggataggat tgtatattca tggcaaaatg ataaattaag gataggagct
      661 gatgataatg atgttctaga aatcaaagga aactcaattt tttggtcaga ttttatttct
      721 tgttgtgacg ggaataatag tatcaaagac attcaaaaac tattgaatat aaaatataat
      781 atttcagaag aaataattac agagtattta gataaattct caaatcgaaa tttattggaa
      841 atattggata atccaataaa tcaattacag gattataaat caattgagtc gttagaaaca
      901 tattatgcta gtgaaggaat tggtgggatt aaactattaa aaatgttagg gaatctaaag
      961 atttctattc tgggatgtgg tggtggtgga tctcatattg cattacaatt agctcaatta
     1021 ggagtgggaa gaattcattt ggtggattac gatattgttg aagaaaacaa tatcaacaga
     1081 caatccatgt tcacatttaa cgatgtcgga aattacaaag ttgattgtgt agccaaaaat
     1141 attcagcaaa gaaattctaa atgtttggtt accaaaagca cttctaaaat gattaatgta
     1201 cctgatgtaa aaaaaagaaa tatctgaaag cgattgggta ttctgttgca tggatgaacc
     1261 tccttatata gcacagagga ttgtaaatag agcatgttat ttattaaaaa ttccaagtat
     1321 atactgtttt agccaacgta gtgcggggaa acttttgttt tgtaatccta atattgaaga
     1381 ttctggctgt attgattgtt tgttatctga acaagataat gaaaactttc aaaagctggt
     1441 gacaacgttc actacctata ataggaaatt ggtaactgca aatatcttac caaatatttt
     1501 attattgaca tcgtgggtgg ttaaacgatg gttagattgt gtaacagata aaaatagtaa
     1561 tgtatggaat atgttgttga gatttgattt ttataaatat atggaagaaa aatttcaata
     1621 tttttcgaaa caagatagtt gtccaacatg tgctaagggt cttagtacaa gtaaattatg
     1681 ggagatttta aaaatagatg aataaaaaaa ttatttttaa aggtgatcaa gatagtaaat
     1741 ttgcttattt ttcattgatg ttttctgcag gtactgccat tgaaaataca gaagaacttg
     1801 gtttttcaca tttgatagag catttattat tacgatcagg cggagaacaa tcattaaatg
     1861 aactatttga taataatggt gcatttattg gaggtgaaac ttctagagat tatattaatt
     1921 tgatgggtta ctgtaaggct gaaaatttca aaaatatatt tgaagcaata gtaagtaggg
     1981 tatttaattt aaatcttact gaagaagaac tgctaagaga aaaaagggta gttttagttg
     2041 aactaacaca gtacgagaat gggagcaaaa cagaaaaatt agtttcggat aaccgcctaa
     2101 tttttaaaaa tagtaagtgg tcagaagata ttattggtgt tagggagaat attgaatctg
     2161 ttgatttgaa aaagctttat aagttttaca ctgagaatat ccaaaacgga gaatttcaaa
     2221 ttgctatttc aggaccgaat cacttaaaag aagaaatagc gattattgaa aataaattac
     2281 cagttggaag aactcctgtt aaatctaatt ttcctatttt ttctagtggt gtaacagaac
     2341 gaaagaaaaa tcaacaggtt tctgaaattt caatgtatat tgatatttca aaaatgacaa
     2401 catcatctca tgatgtagcg atattaacaa ttttaaatgc gatgttaaca ggagttaagg
     2461 gttcagtgtt aggaggtaaa ttaaggacga aaaaccaatg ggtatataat ataatttcat
     2521 tcccaatctt ttacaatggg ctcactatcc taaagatact gactagaacg cctgaaattc
     2581 ataagcatca agtagtacaa gttctaaaag aagacttagt aaatagagaa gacttaaaaa
     2641 atacgaaatt atttgataaa gctaaaaaaa gagttatcaa tgaagttctt atgagctatg
     2701 aagtgaagaa agtcgagttt ttaaagacac tttgcaggga gaaattattt aatataccta
     2761 gttgggagag tgttactggg gaaattgaga aagtttctct caatgaactt aatcaatttg
     2821 ctaaagatgc tctcatgcaa aacaagcaat ttcatatcat aataaattgc taatatattt
     2881 gttaaagtgt tcttgataat tttgataaat tgttttattt aaagaattga agatttttaa
     2941 ggcttcttct atcttagagt ttgatttttc tgtgtgaata ttaaatttca actctaggta
     3001 tccttctagg tataacaata tagttaactc aaaaaaataa gttgagttag ataacaggtt
     3061 tttactagct tgatttaaaa atattgcttc ttcataaaaa tcattttcaa tcattaatag
     3121 aagactatta aggagtagtt gaattagcga ctgtttatta cgaggaattg aattgtataa
     3181 ttttcctttt tttagagctt ccttagtata cttgaataat agtttaggag gtaaagaacg
     3241 acagcaattt ccaagaataa gggtttcata gtatccccaa ttttctaagg aaaataaata
     3301 atttgaaaga taagagatat cttgattagt taattggtga ttgttatcaa gtccagaaat
     3361 gatactttgg ataaaaattg aatttaattt atgataatga gagtttgtct cttcaaacaa
     3421 tttattttct tgttctatca tacttattag tgtttcgact ttattattgt atgcagaatt
     3481 ttgaacagct tttattagtg tattaaattc agatggttca taattgttac aggcgagcaa
     3541 gaattcttca aaggttattc cgagtttttc tagtaaatat aataacttga aaatagaaat
     3601 ttccgtctct cctaattcaa atcttgaaat ttgagatttt gaaatttcat atcctgctaa
     3661 tgaagaaata gaaattcctt tttcttcccg catttttcta taggtttcac ctaagatcat
     3721 agattatctc cgtttgtagt taaaaagtgg aaagcgtgac aaatgatgag aaaaagttac
     3781 aagttactta aattgattct tgatattatc attattatag gtttatgtca ataatttttg
     3841 tagattgcat gaagtata
//
LOCUS       DARYNN010000096         3757 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.097, whole genome shotgun sequence.
ACCESSION   DARYNN010000096 DARYNN010000000
VERSION     DARYNN010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3757)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3757)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3757
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.097"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(40..588)
                     /gene="raiA"
                     /locus_tag="TVB59_001964"
     CDS             complement(40..588)
                     /gene="raiA"
                     /locus_tag="TVB59_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEL1010810.1"
                     /translation="MIKFSIRGENIEVTEAIRDYVESKLTKIEKYFVEEQEIDARVNL
                     KVYREKTAKVEVTIPLGSVTLRAEDVSQDMYGSIDLVVDKIERQIRKNKTKIAKKHRE
                     KMSTSQVFTSEFEAEKAEETPEIKVVRTKNVTLKPMDVEEARLQMELLGHDFFIYTDA
                     EDGATNVLYRREDGDLGLIEAK"
     gene            complement(664..1245)
                     /locus_tag="TVB59_001965"
     CDS             complement(664..1245)
                     /locus_tag="TVB59_001965"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEL1010811.1"
                     /translation="MCDACQRHFCRITQPTCSNCYQYRHEGACQDCIAWKRQGYQVDH
                     QSLYQYNTAMKDYFSRYKFQGDYVLRSLFAQELAKHIKKYYKAYTLVPVPVSKQRYDE
                     RGFNQVTAILEYANLAYLDLFERIDDTRQSSKTKKERLQLNNRYRLKKGAALPPKILL
                     IDDIYTTGSTIMSLRQELVRHGCQDIKSLSIAR"
     gene            complement(1473..1658)
                     /locus_tag="TVB59_001966"
     CDS             complement(1473..1658)
                     /locus_tag="TVB59_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEL1010812.1"
                     /translation="MLTYEEFKQAIDHGYITGDVVMIVRKNGQIFDYVLPGEEVQPWE
                     VVTVEAVADILNELQII"
     gene            complement(1780..2568)
                     /gene="spel"
                     /locus_tag="TVB59_001967"
     CDS             complement(1780..2568)
                     /gene="spel"
                     /locus_tag="TVB59_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeL"
                     /protein_id="HEL1010813.1"
                     /translation="MRIFLRQNCRLVNMSTTFFIVVLSLVVFSVRMVSAEGTINIKDI
                     YSPRWDVDKTLSPTTLREIYNRDTIKKENKPVTGKRGTQVIIDAQHKTKVWEFDDYNF
                     IISSNLYPSVEGKFNVGDNVDVFGLALSAEVFSKDQIHSINGGLVKVNERKGAGKTIY
                     MNVFIDGHKKDETSKYKITFEKSPVTFQEVDVRLRKSFMLNDEIKLYQYGSKVLSGNW
                     EFHGSGENEEGADLFKYPDYRYNNLIDIDKKSHIDVYLFTNKEN"
     gene            complement(2835..3626)
                     /gene="spek"
                     /locus_tag="TVB59_001968"
     CDS             complement(2835..3626)
                     /gene="spek"
                     /locus_tag="TVB59_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeK"
                     /protein_id="HEL1010814.1"
                     /translation="MRRKNEKNTLALLFLVCVSLTLCTTESVFSDTYNTNDVRNPRNI
                     YAPRYDKDEILDNRRLKEIYNKEIIEKNNISINAKQGTQLIFNTDENTTVWNDNTFKK
                     VISSNLSPSQERMFNVGDHVNIFAIVKSYHVVCKEQFNYIDGGIIKTSDVKPEEKAIY
                     INIFGEKELRTLTAKDKITFKNNIVTLQEIDVRLRKSLMGDSKIKLYEYDSLYKKGFW
                     DIHYKDGGIRHTNLFTYPDYTDNETIDMSKVSHFDVYLNEEFSKN"
BASE COUNT         1137 a          745 c          541 g         1334 t
ORIGIN      
        1 gcaaaaaaac aagaggtgag atgcctcttg tttttcaaat tattttgctt cgataagtcc
       61 taagtcacca tcctcacgac gataaagaac atttgttgct ccgtcctcag catctgtata
      121 gatgaagaaa tcatgcccta gaagttccat ctgcaagcga gcttcctcaa cgtccattgg
      181 ctttagagtc acatttttcg tgcggaccac tttgatttct ggagtttctt cagctttttc
      241 tgcttcaaat tcactagtaa acacttgact agttgacatt ttttcacgat gctttttggc
      301 aatttttgtt ttattttttc taatttgacg ttcgatttta tcaacgacta aatcaataga
      361 accatacata tcctgtgaaa cgtcttctgc acgaagtgtc actgaaccaa gcggaatagt
      421 gacttcaacc tttgcagtct tttcacgata aacctttaaa ttaacacgcg catctatttc
      481 ttgctcttca acaaaatatt tttcaatctt agtaagcttt gattctacat aatcgcgaat
      541 agcctctgtc acttcgatgt tttctccacg aatactgaat ttaatcataa gagtacctct
      601 ttcttgcgtt taaaacgctt tctttagttc tactatagcc gttttcatga aaatttgcaa
      661 gttttatcgt gcaattgaga gacttttgat gtcctgacag ccatgcctga caagctcctg
      721 ccttagactc attatggtgc taccggttgt atagatatcg tcaattaata agattttcgg
      781 tggaagagct gctccctttt tgagtcgata gcggttattt agctgcaggc gttctttttt
      841 cgttttgctt gattgtctag tatcgtcgat tcgctcaaat aggtcaagat aggctaggtt
      901 ggcatattct aaaatagctg ttacttgatt aaagcccctt tcatcatacc tttgcttgct
      961 aacaggcaca ggaaccaaag tataggcttt ataatacttt ttaatgtgct tagctagctc
     1021 ctgcgcaaaa agactgcgta aaacataatc tccttgaaat ttgtaacggc tgaaataatc
     1081 cttcattgcg gtgttgtatt ggtaaaggct ctgatgatca acctgatagc cttgcctttt
     1141 ccaggcaata caatcctggc aggcgccctc atgacgatac tggtagcaat tagagcaggt
     1201 tggctgagta atcctacaaa aatgacgctg acaggcatca cacataagat ccttattagg
     1261 acttaacaac agaattgctg tgatagacaa gctatcttta ctatttattg tggcagagta
     1321 gacagttcat tttgataccc tttttgattc atgtccttta tctcccgcac tgccttgagc
     1381 atagcctggc taataccatc atgaaaaaat agcacctgtc cttcaggtct ttccaaagag
     1441 cgcccaacgc gacctgaaat ttgaattagc ggtcaaataa tttgtaattc gtttaaaata
     1501 tcagcaactg cctcgactgt caccacttcc caaggctgca cttcctcccc tggcaacaca
     1561 taatcaaata tctgtccgtt tttacgcacg atcatgacca cgtctcctgt gatatatcca
     1621 tgatcaatag cttgcttaaa ttcctcgtat gttagcataa attacctcct tatcttatta
     1681 ttcgtaaaaa tctggtattg gtatattgga cacatttata tgtaccgaac aaaaaaacgc
     1741 cctcaattaa gagggtattc cttggtttct tgatactaac taattttctt tgtttgtgaa
     1801 tagatagaca tcaatatgac tctttttgtc tatatctatc aaattattat atctataatc
     1861 tgggtattta aataagtcag caccttcctc gttctcgcct gagccgtgaa attcccagtt
     1921 tccagataga actttggaac catactgata aagttttatt tcatcgttca gcataaatga
     1981 ttttctcaat ctaacatcaa cctcctggaa ggtaacggga gatttttcaa aagttatttt
     2041 atatttcgag gtctcatctt tcttatgccc atcaataaaa acgttcatgt aaatcgtttt
     2101 tccagctcct tttctctcat taactttaac gagaccacca ttgattgaat gtatttgatc
     2161 ttttgaaaat acttcagccg ataatgcaag accaaaaaca tcgacattat ctccaacatt
     2221 aaatttacct tctacagatg ggtataggtt acttgatatt ataaaattat aatcatcaaa
     2281 ttcccatact ttagttttat gctgagcatc tataataact tgcgtccctc tttttccagt
     2341 aacgggttta ttctcttttt ttatagtatc tctattataa atttctctta aggtagtagg
     2401 ggataatgtt ttatctacat cccaccttgg agagtatata tccttaatat taatagtccc
     2461 ctccgcagaa accatcctaa cagaaaatac caccaatgac aatactacta taaaaaaagt
     2521 agttgacata ttaaccaaac gacaattctg acgtaaaaaa attctcattt atcttattat
     2581 tctccttaat aaatcaatat agctgtgaaa ctatgttttt tgaacttgaa cctcaaaatg
     2641 cttaaatcgg aagtacttga gcagacttct taaaagataa taaactgatt ctataacgca
     2701 cagaaattaa tctgagcggt tttatcatat tcctcggttg accgatagtg atgcctagaa
     2761 gtctactaaa accgtctaat tcatcaaaat ctatttaaat agactaaaaa ttaaattaaa
     2821 atagcattcg accgttaatt tttagaaaat tcttcgttta agtaaacatc aaagtgacta
     2881 actttactca tatcaatcgt ttcattatct gtatagtcgg ggtaagtaaa taaattggtg
     2941 tgtctaatgc caccgtcttt ataatgaata tcccaaaacc cttttttata caaagaatcg
     3001 tactcataca attttatttt gctgtctccc atcaaacttt tcctaagtct aacatcaatc
     3061 tcctgaagag ttacaatatt atttttaaag gtaatcttat ctttagctgt taatgttcgt
     3121 aattcttttt caccaaaaat attaatataa attgcttttt cttctggttt tacatcactt
     3181 gtttttatta ttcccccatc aatataattg aattgttcct tgcatacaac atgatatgac
     3241 tttactatag caaaaatatt cacatgatca ccaacattaa acattctttc ctgtgaagga
     3301 gaaagattac tagatatgac tttcttaaaa gtgttatcat tccaaactgt agtattttca
     3361 tccgtattaa aaatcaattg cgttccttgt ttggcattta tcgatatatt atttttttca
     3421 ataatttctt tattatatat ttcttttaat cttctattat ctaaaatttc gtctttatca
     3481 tatctaggag catatatgtt ccttggattt ctaacatcat ttgtattgta cgtatctgaa
     3541 aagacactct cagtagtgca tagggtaagc gatacacaca caaggaatag caaagccaag
     3601 gtattttttt cattttttct cctaatattt tttaaattta atcaatttac ttagcaagta
     3661 tactatattt aaataataat tcaactataa tttaaaaaaa acaaaaaacc gccctcaatc
     3721 aagagagcgg ttttgtctta tctcggatct ttacctc
//
LOCUS       DARYNN010000097         3669 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.098, whole genome shotgun sequence.
ACCESSION   DARYNN010000097 DARYNN010000000
VERSION     DARYNN010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3669)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3669)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3669
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.098"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(50..892)
                     /locus_tag="TVB59_001969"
     CDS             complement(50..892)
                     /locus_tag="TVB59_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1010815.1"
                     /translation="MDLLIEKESQATRLSDFGIYNIAIEDSAPLLSVSHRAVKGRSGY
                     IYDGATFTTKTLKVKGRVTVSNVERLLDKQDELNALLVVDEPFYVTKMYPENSDLFNF
                     ELPGESTGDLQLIGSPHKPWKYRFKVILDDTIAYEFIGKTSQGLKYNLSFALRTAELP
                     FGETKPKDITLSGGSFAYAGTAKASQLEWPFIIELTPSGGQTNFYIEIDGRRFEFKQN
                     SQLQNSDKLLLTGIATTLNGNYVNAKTNYEYFIFNPNPNKRITYKTDFLGTIRILNFV
                     ELYK"
     gene            complement(904..>3669)
                     /locus_tag="TVB59_001970"
     CDS             complement(904..>3669)
                     /locus_tag="TVB59_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1010816.1"
                     /translation="LKPAITSVFDTINSLIPNAVAAFARLKQSINIDFSPLGASVKEV
                     FALINIVFGDFAHTGELSEQAFDNLKAKITSLAPKVIALWAVMNPASAISTIMPLLSL
                     FGKVGLALGSLGTSVGAFGGIISSGIASASGVVGAFAATLSGLPGVFATAAGRGLSVL
                     GTMTSAMSSLVSLALAAIGPAAILGLVVAGLGLINSQFGAQIEQLLNTAVTKGPGIIQ
                     GLVKGITSKIPVLIASGTQLIAKFANAIAVLLPVIIQAGVQLITSLVQGIGQNATNLI
                     SSAIKIIGSFVSSIASALPQLISVGMELLLNVVNGIVQNIPLIIQQAQQIIDSFGNSL
                     QANLPSIISNGIAILVNLVQGITQMLPTVLQIATQVITSFVSGIVQFLPQLLQGGIQI
                     IISLVQGIIQNLPQIAQSAVQIIQSLASGLTQALPQIIAAGIQLVAQLAVALIKGLPQ
                     IISAGIQLIMGLGKAMLGAIPNALSGVWEGIKSGFSSMWDQITGKSSTSTAKVSADAT
                     VMAMNVGMQTTAMANQANTDTTSMLNSISQNTELANINATSNATQMANNVNAQTGTMS
                     LQGLNDSMSLASGISTNMSVANINATTQAREMASGVNGATSSMNLDAINHTLSLASGV
                     GANMGAASTGATSQAQAMSSGVSNSLASMQSNSTKAASGLSNSVTSEMSSAATSATSS
                     VNRLSSAVESGFNKAKTSATTSMNGIANAVKTGFSSINSTAKQSMANLVSSVTSGMSR
                     ATAVSNNACQKILSIFRALAGQMSSAGAYAGQGFANGLASSAGTIYAIANSIAANVAA
                     TIRRALDIHSPSRVTKTLGAFTGEGFALGMAEWIGEINSLGKAYATAVTDQNWGVNST
                     VSTSAKVNNSGINTSLDNLSEEVRQSQLSEPIFEVHNEIVGDKIYTAVKEKESREQSK
                     DSYFVFD"
BASE COUNT         1068 a          828 c          706 g         1067 t
ORIGIN      
        1 ccccatactc aatgtcacga tgatccaaaa aagtaatcat tagacctccc tatttataca
       61 actctacaaa atttaaaatc ctaatcgtgc caagaaaatc cgttttgtaa gtaattctct
      121 tgttaggatt aggattgaag ataaaatact catagttcgt tttagcattg acataatttc
      181 cgtttagtgt ggtagctatg cctgtcaaaa gtaatttatc actattttgt agctggctat
      241 tctgcttaaa ctcaaagcgc ctgccatcaa tttcaatata aaaattagtc tgacctccag
      301 aaggagtaag ctctataata aaaggccact ctagctgact tgctttagcg gttcctgcat
      361 aggcaaaact gccccctgat agagttatgt cctttggctt tgtctcaccg aaaggtaatt
      421 cagcagttct tagcgcgaag gaaagattat attttagtcc ttgactggtt tttcctataa
      481 attcataagc gatagtgtcg tctaagatga ctttaaatct atatttccaa ggtttatgag
      541 gagagccaat aagttgcagg tctcctgtgc tttcccctgg aagctcaaag ttaaatagat
      601 ctgagttttc agggtacatc ttagtcacgt agaaaggttc gtcaacaaca agcagagcgt
      661 ttagttcgtc ctgtttgtcc aaaagtcttt ccacgttgct taccgtcact cttcctttga
      721 ccttaagcgt tttagtcgta aaagtagccc catcgtagat gtaaccactc cttcctttga
      781 ctgctcggtg tgatacagat agtaaaggag cgctatcttc aatagcaata ttataaatac
      841 caaagtcaga caacctagtt gcctgactct ctttttctat taataaatcc aaaatactcc
      901 cttctagtca aaaacaaaat aagaatcttt agattgctct cttgattctt tttctttaac
      961 agccgtgtaa attttatctc caacaatctc attatgcact tcaaagatag gctctgacaa
     1021 ttgagactgc ctaacctctt cgctaagatt atcaagagag gtattgattc cactattatt
     1081 aactttagca gatgttgaaa cagtactatt taccccccag ttttgatcag taactgctgt
     1141 tgcgtatgct ttacctaggc tattgatctc acctatccac tctgccatac cgagggcaaa
     1201 cccctctcca gtaaatgcac ctagtgtttt agtgacacga gatggtgagt gaatatctaa
     1261 agcgcgtcta attgttgctg ctacattagc ggcaatgctg ttagctattg cgtagattgt
     1321 gcctgcgcta ctagctagac cattagcaaa accttgacct gcataagctc ctgcagaaga
     1381 catctgccct gccaaagccc tgaatattga gaggatcttc tgacaagcat tattagacac
     1441 cgcggttgca cgagacatcc cagaagtcac tgaacttaca aggtttgcca tagattgctt
     1501 tgcagtactg ttaatgctac taaatcctgt tttaaccgca ttggctatcc cattcattga
     1561 ggttgttgct gaagtcttcg ccttattgaa gccagactcg accgccgagg acaacctatt
     1621 aacgcttgag gttgcagagg ttgctgcaga agacatttcg cttgtcacac tattagacag
     1681 accagaggct gctttagttg agtttgactg cattgatgcc aggctgttac tcacccctga
     1741 gctcatagct tgcgcctgag aagttgcacc tgtgctagca gctcccatgt tcgcaccaac
     1801 accactagct aagctgagcg tatgattaat ggcgtctaga ttcattgaag aagtcgcacc
     1861 attaacccct gaagccattt ctcgagcctg agtagtagcg tttatattag cgacagacat
     1921 attagtgcta atgccactcg caagagacat cgaatcattc aacccctgaa gactcatcgt
     1981 tcctgtctga gcattaacgt tattagccat ctgtgtggca tttgatgtag cgtttatatt
     2041 agcaagctct gtattttgac taatgctatt aagcatagat gtcgtatctg tattagcttg
     2101 attagccata gctgtcgttt gcatcccaac attcatggcc atgaccgtgg cgtccgcaga
     2161 gactttagct gtacttgtgg aactcttacc tgtgatttgg tcccacatcg aactgaatcc
     2221 gctcttaata ccttcccaaa ctcctgaaag agcgtttggg atagccccta acatggcttt
     2281 accgagcccc ataattaatt gaatacccgc agaaataatc tgtggaagcc cctttatcaa
     2341 ggctacggct agttgcgcaa caagctgaat gcctgctgcg ataatctgag gtagagcttg
     2401 cgtcagtcca gaagctaaag actgtataat ctgtacagca gattgtgcaa tctggggtag
     2461 attttgaata atcccctgca caaggctaat aatgatttga atgccacctt gaagtaactg
     2521 cggtaaaaac tgtacaattc cagatacaaa actcgtaatg acttgagtag ctatctgcag
     2581 aacagttggc aacatttgag taattccctg tacaagattc accaaaatag ctataccgtt
     2641 gctaataata ctaggaaggt tagcctgtaa actattccca aaactatcaa taatttgctg
     2701 ggcttgctgg ataataagag gtatattttg aactatgccg ttgacaacat ttaataatag
     2761 ctccattcca acagaaataa gctgcggcaa tgcactcgca attgaactaa caaaactacc
     2821 aatgattttt attgctgaac taattaaatt cgttgcattt tgtccaatac cttggacgag
     2881 actcgtaatt agctgaacgc cagcttgaat tataactggt aataacactg cgatagcatt
     2941 tgcaaattta gcaatcaatt gagtgccact agctatcaaa actggtattt tagaagtaat
     3001 tccttttaca aggccttgaa taatgccagg accttttgta actgcggtgt taagtagctg
     3061 ctcgatttgt gcgccaaact gactattaat caaaccaagt cctgccacca caagacctag
     3121 aatagcggcc ggtcctatgg ccgccagtgc taaactcaca agactggaca ttgcgcttgt
     3181 catagttcca agcacagata gcccacgccc tgctgcggta gcaaaaacgc caggtaatcc
     3241 gcttagagtt gccgcaaagg caccaacaac gccgctggca ctagctatcc cactagaaat
     3301 tatgccgcca aacgccccga cagaagtccc taagcttcct aaagctagac caacttttcc
     3361 gaatagagaa agcaaaggca ttatcgttga tatagcgcta gcggggttca tcactgccca
     3421 aagggcaatg actttaggag ctaaagaagt gatttttgct tttagattat caaaagcctg
     3481 ctctgataat tcaccagtat gtgcaaaatc tccaaaaaca atattaataa gagcaaacac
     3541 ctctttaacg ctggcgccta atgggctaaa gtcaatattg atagactgtt ttagcctagc
     3601 gaatgctgca actgcatttg gaataagaga attaatcgta tcaaaaacac tggttattgc
     3661 tggcttcag
//
LOCUS       DARYNN010000098         3419 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.099, whole genome shotgun sequence.
ACCESSION   DARYNN010000098 DARYNN010000000
VERSION     DARYNN010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3419)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3419)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3419
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.099"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            1..1588
                     /locus_tag="TVB59_001971"
                     /pseudo
     CDS             1..1588
                     /locus_tag="TVB59_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893534.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="Dam family site-specific
                     DNA-(adenine-N6)-methyltransferase"
     gene            complement(1609..3222)
                     /locus_tag="TVB59_001972"
                     /pseudo
     CDS             complement(1609..3222)
                     /locus_tag="TVB59_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677638.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
BASE COUNT         1195 a          664 c          456 g         1104 t
ORIGIN      
        1 aaaatactga aaaaattgat aatatcagac agatcataga agattggaac aacaatcaat
       61 tactcacaga gtacgaatat ttttaccttt taaatgcttt gatagaagct attccttatg
      121 ttagtaatat tactggaacc tatggcgctt ttctcaagca ttgggacaac cgagcgttgc
      181 attccttaac attagcagaa gagactattt ttgataatta tcgtcctaac aaagcgttta
      241 atgaaaatgc taatgaatta gtcaaaaaaa taaaagcaga tattgtttac attgataccc
      301 cctacaatgc tcgacaatac gcatcaaatt atcatttact cgaaaacatc gcccgacatc
      361 aaaagccaat tttaaaaggg attactaaaa tttttgattg gaaaactctt aaaagtgatt
      421 attcaacaaa aacaaaggct ttaaaagcaa tggaagattt aattgctaat attaatgcta
      481 gtcatatcat tctaagttac aataccgagg gtattatatc cgaagaagat ttaacacttt
      541 tacttcaacg atattcgttc aataatcaaa ttgatgtgaa acggattcct taccgaaaat
      601 atcaatctaa gaaaaaatct cagaacaaag acttatacga acttcttttt tatattcaaa
      661 gaaagccgat aaataatcgc ttcaaatcac aaactaaaaa aaaggcagcc atcatcagtc
      721 aaaaaaagta tataaaaagc ccattaaatt atatcggtgg aaaatatcga ctgctaaatc
      781 aaatcattcc aatttttccc cgacatatca atacatttgt tgatatgttt agtggggggc
      841 aaacgttggt atcaatgttc ctgctaaaaa acacatcttt aatgatatga actatcgcat
      901 taatgacatg tttcgatatt ttcaatcaca tgacccactt gagatacttg aacaaattga
      961 gcatcgaatt tcagaatatc aactcagcaa gaccaatgaa caaggctttt taacattccg
     1021 aaaacattat aatactcatc caaatccact agacttatac gtactatcgt cttatagcta
     1081 taactatcaa tttcgcttta ataactcaat ggaattcaat aacccattcg gcagaaatag
     1141 aagtcatttt agtgaaaata tgaaatccaa tctactcaat tttgtagctc gactacaccg
     1201 tttagatgcc actttctctg atcaattttt ctcagatttt gatatttcta cattatcaat
     1261 agatgatttt gtttatcttg atccccccta cctcataacg actggcagct ataatgatgg
     1321 aaatcgtggc ttcacaaact ggggcgaaaa acaagaaatt gaaatgtatc aattaataag
     1381 agaccttaac aagaaacaaa ttaaggttgc acttagtaat gttcttgttc ataaaggaaa
     1441 gcacaatgat ttacttgagc aatttgttca agatgaaagt ctatatctca ccactttaaa
     1501 ttacaattat aaaaatgctt catacaacac aagaaaagaa gatagcattg aagtattgat
     1561 taccaattat aaaccaaatc caaaataata aaagcatagt tgaattagct atgcttttac
     1621 aaattcaatt tctttatttt gaaaataaga tggtaaatcg gaaatatgca gttgtccttt
     1681 aagaaccaaa tctgctccca aaagcaattg ctctacattg agggctgctc ccttaatttg
     1741 tgtttcatta gaggtataat caagctgctc ttgaaatttt ccaatgaatt tacttgacac
     1801 ccacataaaa taaaactctt cttgtggaat cgtatctgga aaagcttccc accactttat
     1861 cggattacga ttttcatctc gtcgcttatt atcctcaata taccgaatca tttcatcagc
     1921 ctgattgata gatttagaat aaccttttcc ataagccttt gtatctacaa tcacaccaaa
     1981 acgatcttga tagagtaaac catctggctt tctgccacca cctaaaagct tagaatgcaa
     2041 tctatataca tttctaaata attccattgt aacaatttca aaatctcgat ttcgcttacc
     2101 atcgtaagca atatcaagca attcaatata tttcattggt aaattagtct cttttaaaaa
     2161 ttttgcctta cgcttttctg cctgctcatc ctttaattct tgtgtaattt ctagttcagg
     2221 aatagaaaaa tcgttgatct tatccttcaa agaaactcta ttgctagaaa tatctatcct
     2281 caaaccaaaa taattcaatc cttgaatatc tgataagata atctccagtt catcgtaaaa
     2341 acccttagcc cttagtttat ctaatagaat agccaaagaa ttagtttctt ggagaaactt
     2401 gacgatataa gctctccgag tacgaacata ctcgcgatta ttgccatgag ttgcaaaaaa
     2461 ttcccacatc acaaattttt caagcttgct atgcttagaa tccccctgag cttgtcgtaa
     2521 agcatgaaga ccacgaccat taattttata accttgaaat ccatcttttt caccattagt
     2581 aaaggtacgc ttaatcgttt gtgaatcaac caaaccaaca ttttttagcc aattacaaat
     2641 accgcgtgca tatttatcac ttgttccttc tatatcagct ttaataagtt ttttctctga
     2701 tttagtggca gatcctaacc aatcaaacat aatatcttca ttataggaag taaagccttt
     2761 ttcaccacga aaaccaagct gctcacctaa ataatattta gtacaataag taccgctatc
     2821 agccaataaa gataagattt gtgtagctgg cgggtatgac aacagtgcct ttcttaaaat
     2881 agcagtttct tcttccgaat taattattgc cctagaaaaa tgcaacccct tcgaagtaat
     2941 tgaaaacata tccgtttctc tatctaccga cacaaaattc aggctaacag cccatcttaa
     3001 aaaaccatct gatgtccaat tatccgtcca agttttacct gtattttttg cctgttgagg
     3061 tacgatgctg atttgaatca aagaatctgc cattgcatct gaacgctttc ggggagattt
     3121 gttattctta tcctttgatg ttccaactaa ttctaaatat gaaaatgatt gaatcccatt
     3181 aatcagtttg tttctgagtg attctcgtgg tacttcaaag aaatctgtac ccaaccataa
     3241 gttcttattt tcataagagc tccttaatct tatacttatt atctttatta tagcatataa
     3301 ttaatccttc cagttagcat tatcacaaag caacaacatt tcttatttaa tggggctact
     3361 atgtagctat tttaatacat gtttttacct cacgaaaaca cccccacttg tcaagtctg
//
LOCUS       DARYNN010000099         3227 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.100, whole genome shotgun sequence.
ACCESSION   DARYNN010000099 DARYNN010000000
VERSION     DARYNN010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3227)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3227)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3227
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.100"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            <1..1678
                     /locus_tag="TVB59_001973"
     CDS             <1..1678
                     /locus_tag="TVB59_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="HEL1010817.1"
                     /translation="AQVIKDRIAEQRFADKISVIEETITEEEFDLTDVQHAYYVGRNK
                     DMILGGVSTHCYFEIESSDIDVNKLEKAWNYLIKIHPMLRAIITENGKQKILQEVEYY
                     KIMTSADSELIIRDIMSQQVLNLDKWPIFDIRISKREDKADIIHISFDNIILDGWSMF
                     FILEQWSNIYKYGKYEEAINEISFREYVNYINKLKSTPKYFTDKEYWINRIEGFLKAP
                     IISDYYPKTTSKQIKFSRREAYIEPLRWKSLKNIASKNNLTTTSLLIGAYAEAIREVS
                     LNENFTINVTRFNRPQINGKTNSTLGDFTNLLLLEINNSKHEKILDRFREIQGQLIED
                     LSHELFSGIEMQKELRKIEKDNLVLMPIVFTSGIGINSWDDDERLGKIVYGLSQTPQV
                     FLDNQVFVYNDGLKIYWDSIDEILGEDKVDLMFKKFVIFLTEIADGSFNKESTIAKKR
                     EYTDYIFSNEDIEKQEKEAIKNDVVEINYIEQDMKNIWESILDISIENYDCKFFEAGG
                     DSLRAIQLSNKIQEMFSVNVDLLEIFKNPSIREISLLVSKEKENIIEGSL"
     gene            1675..>3227
                     /locus_tag="TVB59_001974"
     CDS             1675..>3227
                     /locus_tag="TVB59_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEL1010818.1"
                     /translation="MMKKVIICGTRFGQFYIEALKNIQDIEIVGILANGSERSIKCAE
                     YYRLKLFVEIDSLPKDIDFACVAVGSSVFGGNGIYIAKELLKRGVNVIFEQPIHSREI
                     AELYNMSILTNEKFSIGNLYNNLPAVKSFLLNVSIANKIDQPSYIMIDLNTQLSYPVS
                     GIIKKILKDTTEIKENYKYIGEESCCDILSINIGKTEVIIKAFNEMGRKNLDTDMRML
                     FSMTVGYASGRLTLSSPLGPVLWEQSPNVPKIDLIPRFLDGNDNEGCSKPWLSILYEG
                     DTYYKSYVYRNIWVEAIMDDLKEFVFEDKSKKQSNSMKIQHQLETSILWQKIMNSLGY
                     PKQKSLCRNKYIDPDKFKRNEVSCYSIRESVDELNTVCRDTMFYHLSKHIPRQGISML
                     SLVEALMFKDKYKKIIVRWINYLVDFKYLEKNRGYIFSKKEKIDEIDLLKKWDVLESK
                     WNKDAMPINVFQYFRNNARELSALLKEDINANEILFVEGSDVVAKDLYSKTAIARYLN
                     ELIVKKIKE"
BASE COUNT         1286 a          292 c          606 g         1043 t
ORIGIN      
        1 agcccaagtg attaaagata gaattgctga gcagcgtttt gcggataaaa ttagcgtgat
       61 agaggaaact attacagagg aagagtttga tttgacggat gttcaacatg cttattatgt
      121 tggaagaaac aaggatatga ttttaggagg agtttctact cattgttatt ttgaaataga
      181 atcaagtgat atagatgtaa ataagttgga gaaagcgtgg aattatttaa taaaaattca
      241 tccgatgtta cgagcaatta taactgaaaa tggtaagcag aagatactgc aagaggtaga
      301 atattataaa ataatgacta gtgcagattc agaactcatt atccgtgaca ttatgtcaca
      361 acaggtgctt aatctggata aatggcctat atttgacata agaattagca agcgtgagga
      421 taaagcggat ataattcata ttagttttga taatataata ttggatggat ggagtatgtt
      481 tttcattctg gaacaatggt ctaatatata caaatatggg aaatatgaag aagctattaa
      541 tgaaatttct ttcagagaat atgtgaatta tattaataaa ttgaaaagca ctccaaaata
      601 ttttactgat aaggaatatt ggataaatcg tatagaagga tttttaaagg ctccaataat
      661 aagtgattat tatccaaaaa ctacatctaa acaaattaaa ttttctagaa gggaagcata
      721 tattgaacca ttgcgatgga aatccttaaa aaatattgct agtaaaaata atttaacaac
      781 aacatcttta ttaataggtg cttacgctga ggcaataaga gaagttagtt tgaatgagaa
      841 ttttactata aatgttacaa gattcaatag accacaaata aatggaaaaa caaatagtac
      901 attaggtgac tttactaatt tacttttact tgaaataaat aattctaagc atgaaaaaat
      961 attagacagg tttagagaaa ttcaaggtca attaatagaa gatttaagtc atgagttatt
     1021 ttctggaata gaaatgcaaa aggagttaag aaaaatagaa aaagacaatc tagtattaat
     1081 gcctatagta tttacaagtg gtataggaat aaattcatgg gatgatgatg aaagattagg
     1141 aaaaatagta tatggattaa gtcaaactcc tcaagtattt ttagataatc aggtgtttgt
     1201 atataatgat ggtttgaaaa tttattggga tagtattgat gagattttgg gtgaagataa
     1261 agtagatttg atgttcaaaa aatttgtgat atttttaact gaaatagctg atggctcttt
     1321 taataaagaa agtaccattg ctaagaaacg agaatatacg gattatattt tctcaaatga
     1381 agatattgag aaacaagaaa aagaggcgat taaaaatgat gttgttgaaa taaactatat
     1441 agagcaagat atgaaaaata tttgggaaag catacttgat atttcgattg agaattatga
     1501 ttgtaaattt tttgaagcgg gtggagattc tttgagagcg attcaactta gtaataagat
     1561 tcaagaaatg ttttcagtaa atgtagattt attggaaata ttcaagaacc cttctattag
     1621 agaaataagt ctattagtta gtaaagaaaa agaaaatatt atagaaggga gtttatgatg
     1681 aaaaaagtta ttatatgtgg aacaagattt ggacaatttt atattgaagc attaaaaaat
     1741 atacaagata ttgaaattgt tggtatttta gcaaatggta gtgaacgttc tattaaatgt
     1801 gcggaatatt atagattaaa gttatttgta gagatagact ctttacctaa agatattgat
     1861 tttgcttgtg tagcggttgg ttcttctgta tttggaggta atggaatata tatagctaaa
     1921 gaattattaa agagaggagt aaatgtaata tttgaacaac caattcattc aagagagata
     1981 gcagaattat ataatatgag tattttgact aatgaaaaat tcagcattgg gaatttatat
     2041 aataatttgc cagcagttaa atcttttcta ttaaatgtca gcatcgcaaa taaaattgat
     2101 caaccatctt atattatgat tgatttaaat actcaactct cttatcctgt atctgggatt
     2161 ataaaaaaaa tattgaaaga tactacagaa ataaaagaaa attataaata cataggggaa
     2221 gagtcttgtt gtgacatttt atctataaat attggtaaaa cagaggttat tataaaggca
     2281 tttaatgaaa tgggtaggaa aaatttagat acggatatgc gtatgctttt ttctatgact
     2341 gtgggatatg cgtctggtag gctaacttta tcaagtcctc ttggaccagt tttatgggaa
     2401 caatcaccta atgtacctaa aatagatctt ataccaagat ttttagacgg caatgataat
     2461 gaaggatgta gtaaaccttg gttatcaatt ctttatgagg gagatacata ttataaatca
     2521 tatgtatata gaaatatttg ggttgaagca ataatggacg atttgaaaga gttcgttttt
     2581 gaggacaaaa gtaaaaaaca aagtaatagt atgaaaattc aacaccaatt ggaaacttct
     2641 atattatggc aaaaaattat gaatagttta gggtatccta aacaaaaatc attatgtagg
     2701 aataaatata ttgatcctga taaatttaag agaaatgaag tgtcatgtta cagcataaga
     2761 gaatctgtag atgagttgaa tacagtttgt agagatacaa tgttttatca tttgagtaaa
     2821 catataccta gacaagggat atcaatgtta tcattagtgg aagctttgat gtttaaagat
     2881 aaatacaaaa aaattatagt gcgttggata aattatttgg tagattttaa atacttagaa
     2941 aaaaatagag gatatatttt ttctaaaaag gaaaagatag atgaaataga cttgcttaaa
     3001 aaatgggatg tgttagaaag taaatggaat aaagatgcta tgcctataaa tgtatttcaa
     3061 tattttagaa ataatgcgag agagttaagt gctctattaa aggaagatat caatgcaaat
     3121 gaaattttat ttgtagaagg tagtgatgtg gttgccaaag atttgtattc aaaaacagca
     3181 atagcaagat atttgaatga attaatagtt aaaaaaatta aagaatt
//
LOCUS       DARYNN010000100         3098 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.101, whole genome shotgun sequence.
ACCESSION   DARYNN010000100 DARYNN010000000
VERSION     DARYNN010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3098)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3098)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3098
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.101"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(<1..1398)
                     /locus_tag="TVB59_001975"
     CDS             complement(<1..1398)
                     /locus_tag="TVB59_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1010819.1"
                     /translation="MFYLKLAWNNLRKSLSVTAPFLLASTVLYMLNCIVLIIMMSPVS
                     ESMRHGFMLLGLAIFVLIIFATIMEIYSYNFLLKQRSREFGLYNILGMNKKQVGLVST
                     IELVFMYLGTVVVGSILSAIFSHVFYLIFANLVGAVHLELQINPVAFIYTTLIFAAIF
                     GLLEVVGLIKIRKTSPLMLFRHKEQGEKEPKGNLLLAALSIILLSIGYYISLSSTKLT
                     ALDTLYRFFIAVIIVIIGTYLFYISFMTWHLKRRRQNKAYFYQPEHFVSTSQMIFRMK
                     QNAVGLANITLLAVMAFVAIATTTALYANSEAMSNQLFPKNTHINFDNSEIDNQKEVF
                     NRLIVEKTNKPASDFLVYYSSMVSFEVSQKETIVVTKESLLNPSPVTTGYVYLVTQDD
                     FRALGNQLPELKDNQTAFFKQRGDSQLRQLDILGKSYTNVKNLTSLRSISDDKGIISD
                     GDTVIGHIETKKEYLR"
     gene            complement(1401..2153)
                     /locus_tag="TVB59_001976"
     CDS             complement(1401..2153)
                     /locus_tag="TVB59_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1010820.1"
                     /translation="MLLEINHLEKVFRTRFSKEETRALQDVDFKVDKGEFIAIMGESG
                     SGKTTLLNILATLEKPTKGSVLLNGTDITKIKEGDLANFRLQNLGFVFQDFNLLDTLS
                     IRDNIFLPLVLNRKPFKEMERRLNIIAPKLRIETLLDKRPFEISGGQKQRVAIARSLI
                     TNPQLLLADEPTAALDYRNSEDILNLFEAINLDGQTLLMVTHSANAASHAKRVLFIKD
                     GRIFHQIYRGNKTNLEFSKDISIAMAGLLGGE"
     gene            2484..2963
                     /locus_tag="TVB59_001977"
     CDS             2484..2963
                     /locus_tag="TVB59_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PASTA domain-containing protein"
                     /protein_id="HEL1010821.1"
                     /translation="MAKKIKKTLGTVGKLFSIIPDTTEIIGKTIDNTRPIIEKHMEQK
                     HEKEMQLTLLDDVINLPVDKAQKHLEQLGFVVALLPVKPSKKWIHASLNEVVSMSPKP
                     GKHKLGSLVKLYYVTVDVLEKSQAILDQETLKAVERNQKIADTIEAVKQIKLPFKKR"
BASE COUNT          996 a          570 c          578 g          954 t
ORIGIN      
        1 tcggaggtat tcctttttag tttcgatatg acctataaca gtatcaccat cactaatgat
       61 tcccttatca tcactaatac tcctaagaga tgttaaattt ttgacattgg tatatgattt
      121 gcccaaaata tccagctgtc gtaattgact atcccctctt tgcttaaaga aggcagtctg
      181 attgtccttt aattcaggca attgattgcc caaggcgcgg aaatcatctt gagtgactaa
      241 gtagacatag cctgtagtga ctggactagg atttagcaag gattctttgg ttactacaat
      301 ggtttctttt tgggatactt caaaagaaac catgctacta taatagacta gaaaatccga
      361 ggcaggctta ttggtctttt caacaataag tctgttaaaa acctcttttt gattgtcaat
      421 ctctgaatta tcaaaattaa tatgagtatt tttaggaaaa agctggttag acattgcctc
      481 gctattagca taaagcgcag ttgttgttgc tattgcaaca aaggccataa cagctaagag
      541 ggtaatattt gccaagccta cagcattttg cttcattcta aaaatcatct gagaggtgct
      601 gacaaaatgc tctggctggt aaaaataagc cttgttttga cgacgacgct ttaagtgcca
      661 agtcataaag gaaatgtaaa agagataggt cccgataata acgataataa ctgctataaa
      721 aaaccgatat aaagtgtcta atgctgtcag ctttgtcgat gataaggaga tgtaatagcc
      781 aatactaagc aatatgatgg ataaggctgc tagtaataaa ttaccctttg gctctttttc
      841 accctgttct ttatgacgaa agagcattaa gggagaggtc tttctgattt taatcaagcc
      901 aacaacctct aataaaccaa agatagcagc aaagattaaa gtggtgtaaa taaaagcaac
      961 gggattgatt tgtaattcta aatggactgc tccgaccaga ttagcgaaaa tcaaataaaa
     1021 gacgtgtgaa aaaatagctg ataggatact tcctacgact actgtcccta agtacataaa
     1081 aacaagctcg atcgttgaga ctaaaccaac ctgcttttta ttcattccca aaatattgta
     1141 cagaccaaat tctcgacttc tttgctttag taaaaaatta tagctataaa tctccataat
     1201 agtggcaaag atgattaaaa caaagattgc tagtcctaat agcataaacc catgtctcat
     1261 cgattctgat acggggctca tcatgataat caagacaata caattgagca tatataaaac
     1321 agtgcttgcc agtaaaaaag gagctgtgac ggataaggac tttcgtagat tattccaagc
     1381 tagtttgaga taaaacatct ttattcacct cctaaaagac cggccatggc aatcgagatg
     1441 tctttgctaa attctaaatt cgttttattt ccacgataga tttggtggaa aatacggccg
     1501 tccttgataa acagtactcg cttagcatgg ctagcagcat tggcagagtg tgttaccatc
     1561 aagagtgtct gaccgtctag gttaatggcc tcaaaaagat tgagaatatc ctctgaattg
     1621 cggtaatcaa gtgctgctgt tggttcgtca gctaataata attgcggatt ggtgattaag
     1681 cttcttgcaa tagcaaccct ttgcttttga ccaccagaaa tttcaaatgg acgtttatct
     1741 aaaagcgttt caatgcgcag cttaggggca atgatgttga gccgtctttc catttcttta
     1801 aatggcttac ggtttaaaac aaggggtaaa aagatattat ctctgatcga tagggtgtct
     1861 aggaggttaa aatcctgaaa aacaaagcct aggttttgaa gtcggaaatt agctaggtca
     1921 ccctccttaa tttttgtaat gtcagtgcca ttcaataaaa cagatccctt ggttggtttt
     1981 tccagagttg ccagaatatt taatagggtt gttttccctg agcctgactc tcccatgatg
     2041 gcaataaact cacccttgtc aaccttaaaa tcaacatctt gtaaggctct agtttcttcc
     2101 tttgaaaagc gtgtccgaaa aaccttctct aaatgattaa tttctaataa catatgaaac
     2161 tcctttgtgt ctattatact cttttagctt taaatatagc cactatcgtg acgtatttag
     2221 ctagtgatgc atttagtgcc ttttgtcagc cttaaccact ccttctttca tgaagcagcc
     2281 cagctctcaa caagaatcgt cttagctgac tgaacctatt gctctaaact cttttttctt
     2341 tacagcttat agtttaccct aattaatagt ctggttagct tacaagattt gatgggtgac
     2401 ttacagattt gtaagtttta taacatcatt tttcttatca ttttgatata atgaaaggag
     2461 aattctattt aggagaagcg tcaatggcta agaaaatcaa aaaaacgcta gggactgtcg
     2521 gaaagctgtt ttccattatc cctgatacca ctgaaattat aggaaaaacg atagataaca
     2581 cccgtcccat tatcgaaaag catatggaac aaaagcatga aaaggaaatg cagctaacgc
     2641 ttttagatga tgtgattaat ttacctgttg ataaagcgca aaagcatctg gaacagctag
     2701 gttttgttgt cgcactattg ccggtcaagc ctagtaaaaa atggatacat gctagcttaa
     2761 atgaggttgt ttccatgtca cctaagcctg gaaagcataa gctgggaagc ttagtaaagc
     2821 tttattatgt tactgtagat gtccttgaga aaagtcaggc tattttagat caagagaccc
     2881 taaaggctgt cgaacgaaat caaaaaatcg ctgataccat cgaagctgtt aagcaaatca
     2941 agcttccttt taaaaagaga taaggctata ctgtaaaaaa taagctgata ccgttaggat
     3001 cagtttattt tttatgttgt gactttaagt ctatctcgct tagcaggtgc caaacaaata
     3061 aaccacccgt tatgtaccga ccttcaatgg ttaaagtt
//
LOCUS       DARYNN010000101         3068 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.102, whole genome shotgun sequence.
ACCESSION   DARYNN010000101 DARYNN010000000
VERSION     DARYNN010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3068)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3068)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3068
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.102"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(1..291)
                     /locus_tag="TVB59_001978"
                     /pseudo
     CDS             complement(1..291)
                     /locus_tag="TVB59_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893534.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
     gene            1348..2862
                     /locus_tag="TVB59_001979"
     CDS             1348..2862
                     /locus_tag="TVB59_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1010822.1"
                     /translation="MLDYYLERDIVERKLILAVLLTEKEITLDSLCSQTSITPRKAKE
                     YLNQINALFDKDLSITVLKSGITCEFDPNNKEKYFHSIYASSDTLKMLKFLLTDNYRT
                     KCLTTFIRRQFISKSKAYHLVNKLKGYLQSIHLDIDDYRVIGDEYRIRYLIAMLHKEY
                     GFAVYEMTPKDMEIIHAFIFLTPTRLKPTVFLDKKFYLFDILLMLSWKRQNYDVSLPQ
                     LTLFDRLKELSIFEQISCYAKQEIETRTQVVFNSGDLDYLYLVYLTVDSSFLMHYWND
                     KQLRLVYNILEEDPLYKELVNRLEMLFGRQLHLRDQMYFLLPFFRRCLFQLHDLISFQ
                     DYYSKRYQGSQLLLEKVEEQIKDWLMVSYQSETLSPGHLHFMCLHLEQMLELSLPPVE
                     VIIVENKRALGDVLSYFVISSIPSYKVNITRINMLTDSLENYEQAPDFVITSDNILPF
                     LEEQQVFPDKSVLIGMSMDYIKEQGKTVVKSILNFHRKHYEQLLEQLLIGDRVE"
BASE COUNT          899 a          462 c          574 g         1133 t
ORIGIN      
        1 ccaattttac cattaagcct ttgtagataa tcaattggat ctaaaattcc tactgctttt
       61 agtttattaa aggataggta agaattattt tctataatag cctttgcttt aacatagtta
      121 aagtataaaa tatcattaga ataaacagta taatattgtt taaagaagtt tgaaaccaca
      181 ttagtgcctg caaataaatc taaaaaaaac ttcttcatca ccagttttat gtttgtctag
      241 catggtctta atttctgtca acaataattt tttagaacca atatatctca ttctacatcc
      301 ttaatcatcc tttagttgtt tcattatagc atattcatgt tgaagttcca atattttatt
      361 tgaaaaatta tcttttgctg tatttcttta ttgtagtttt taagcttagt ttatatgttg
      421 ttgattaaag ggaagaagaa cttaggttat ctaaattgag gaattcgtct gtaggtaaca
      481 atgtattatg tggccgagag atttatttta tatattaatg agatataaga cccctatccc
      541 gtccagcgtg acagacttgc tatggaaaag cttattttga ggctgtctga ggcttgctta
      601 tgtgtgacaa gcatttaggc tagaacgctc acctttttta ctgcaagcaa agctttagaa
      661 gctattgcaa gatactttta ggcttgttac taagcgggtc atctctatca tctcctagag
      721 agtagtggag gctatgacag tttagcatat atggtttctc taatgatttg acgatgtaaa
      781 accataacta ctgttattgt agggattatg tataatatgt ataaaaagag aagggcttgt
      841 ttctcagcgt tatcatttta cctataatgt cgctgccagt ttgcaaggct gctgagatta
      901 gtagcttttt ggctattttt ctcatctttt gtcttatttt tattaaaaat aatgaattta
      961 taaagataat ttttcaaaga atagtcttta agttgacagt agtatcatgt ggcgattttt
     1021 gtcttggttt ttgcatttat ttcggttttt ttatctttaa ttaagttact aatattctga
     1081 ttatgttagt aaaatgacat tctcataaaa tgtctaaaaa aggctaattt gtcaaggtat
     1141 tatcataagg cttgatttta taagctattg actgtatact cttataggtt attttataaa
     1201 atattttcag tcttttttat ttatcatttt cagatgatcc ttgaaaggaa gcagtcgtta
     1261 ttttttgtgt atttttttta gttgactttt aaatcctatc aactaaaatg tatatggtca
     1321 tacaaactaa taaggagaga gattattttg ttagattact atttagaaag agatattgtt
     1381 gagcgaaaac taatattggc tgtcttattg acagaaaaag agattacact tgattcattg
     1441 tgctcgcaga cgtcaataac ccctcgaaag gctaaggaat accttaatca gattaatgca
     1501 ctatttgaca aagacctgtc tattactgta ttgaagtcag gcattacctg tgagtttgat
     1561 cctaataaca aggagaagta ttttcacagt atttatgcat catctgatac gcttaaaatg
     1621 ttgaagtttc tgttgacgga taattacagg acaaagtgtc tgacaacttt catcagaaga
     1681 cagtttattt ccaaatcaaa ggcctatcat cttgtcaata agctaaaggg ctacctgcaa
     1741 tccattcatt tggatatcga tgattaccgg gttatagggg atgagtaccg gattcgctac
     1801 ttaattgcca tgcttcataa ggagtatggg tttgctgttt atgagatgac acctaaggat
     1861 atggaaatta ttcatgcctt tattttttta acccctacgc ggttaaagcc cactgttttc
     1921 ttggacaaga aattttatct ttttgatatt ttactcatgc tgtcttggaa gaggcagaat
     1981 tatgatgtat ccttaccaca gcttacttta tttgatcgtt taaaagaatt atctattttt
     2041 gagcaaatca gttgctatgc taagcaagaa attgagacac gtactcaggt tgtgtttaat
     2101 tctggtgact tagattatct ttacttggtt tatcttacag ttgatagttc ttttcttatg
     2161 cattattgga atgacaagca attacgtctt gtctacaata tcttagaaga agatccgctg
     2221 tataaggagc ttgttaatcg cttggaaatg ttgtttggtc gtcagcttca tttaagggat
     2281 cagatgtatt ttttgcttcc ctttttcaga agatgtctct ttcaattgca tgatttgatt
     2341 agctttcagg attactattc aaagaggtat caaggcagtc agctgctgct agaaaaggtt
     2401 gaggagcaaa tcaaggactg gctgatggtt agctaccagt cagaaacgct ctcaccaggg
     2461 cacctgcatt ttatgtgcct tcatttggag cagatgcttg agctgtcctt gccgcctgta
     2521 gaggtcatca tcgttgaaaa caagagagca ttaggtgatg tcttgtctta ctttgttatc
     2581 tcaagtattc cttcttataa ggttaatatt actcgtatca acatgctaac agatagtctg
     2641 gaaaattatg agcaggctcc tgattttgtg attacgagtg ataatatttt gccttttctt
     2701 gaggagcagc aggtatttcc agataagagc gtcttaattg gtatgagcat ggattacatt
     2761 aaggagcagg gaaaaacagt ggtaaaatca attctgaact ttcatcgtaa gcattacgag
     2821 cagcttttag agcagctctt gattggagat agggtagagt aagttttttt gctaagcaag
     2881 tggtataagg ctgctaggtt tttctttgga ccattttttg tgaggatttg ctttagcgat
     2941 acctgttttg attggcttac tgctgatcgt gataacacct atgctaaata gcagcaatca
     3001 atagctcgtg cctatttggt acaatatttc tgaaaaatcc acttgtgata agcctttcaa
     3061 gtggattt
//
LOCUS       DARYNN010000102         3068 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.103, whole genome shotgun sequence.
ACCESSION   DARYNN010000102 DARYNN010000000
VERSION     DARYNN010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3068)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3068)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3068
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.103"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            18..98
                     /locus_tag="TVB59_001980"
     tRNA            18..98
                     /locus_tag="TVB59_001980"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:52..54,aa:Tyr,seq:gta)
     gene            105..175
                     /locus_tag="TVB59_001981"
     tRNA            105..175
                     /locus_tag="TVB59_001981"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:137..139,aa:Trp,seq:cca)
     gene            187..259
                     /locus_tag="TVB59_001982"
     tRNA            187..259
                     /locus_tag="TVB59_001982"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:220..222,aa:His,seq:gtg)
     gene            268..339
                     /locus_tag="TVB59_001983"
     tRNA            268..339
                     /locus_tag="TVB59_001983"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:300..302,aa:Gln,seq:ttg)
     gene            358..441
                     /locus_tag="TVB59_001984"
     tRNA            358..441
                     /locus_tag="TVB59_001984"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:392..394,aa:Leu,seq:caa)
     gene            complement(785..1915)
                     /locus_tag="TVB59_001985"
     CDS             complement(785..1915)
                     /locus_tag="TVB59_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009855141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1010823.1"
                     /translation="MILRKYNDFCRLFLGRLISNCGDSIYTLVLSWYVLETTNSTWYV
                     GLLNFLIFIPNTFSFIFGKKIDSYPKKNLLVILEWAQLLAVLGIILGMSLREIHASLS
                     LTIIFSCVFLASMVGLNTYTVQDALVPKLIPTKDLAKAEMYMSVAYNGTDYVFTAISG
                     FLLSVISYIPLLFINIVTFLGSILFFRRIAFKEIIEQTNERTDFLSGLRFIWHNKVVL
                     AITLGGAIANFLFASLNVYQLLIAREVGNSAFYGLLVSVSAIGTLVGTTFVANLVLQK
                     LSVGKAFWLATTLLGTGIGLTALVPNRFGLLLLWFLSCLFLGITHVTQKPILRTEIPD
                     EHLGEVFSAFYTVTIPTLALGSLILISLLYFSNKMLRQYDIC"
     gene            2480..>3068
                     /locus_tag="TVB59_001986"
     CDS             2480..>3068
                     /locus_tag="TVB59_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL1010824.1"
                     /translation="MTTKEKQTKLMRRYGIFSVVVALTALAGLGAANEVKATAKKSLN
                     ELPNPVEIIQYNSTRTTDREARKYLNQLYEFLKPYLGSLEEEAQKGGPQGPVGPAGPR
                     GERGEPGPKGDRGPEGQRGEQGPAGPIGPQGPRGDKGETGEIGPRGEQGPTGPTGKPG
                     ERGPKGDRGERGEKGEQGQRGEKGEQGQRGEKGEQG"
BASE COUNT          986 a          571 c          673 g          838 t
ORIGIN      
        1 gtaatttaat atgttttgga aagatagcga agaggctaaa cgcggcggac tgtaaatccg
       61 ctccttcggg ttcgggggtt cgaatccctc tctttccatc ctgaacgggc atagtttaaa
      121 ggtagaacta aggtctccaa aaccttcagt gtgggttcga ttcctactgc ccgtgttcag
      181 aatatggcgg gtgtggtgaa gtggttaaca catcagattg tggctctgac attcgtgggt
      241 tcgattccca tcactcgcct attttattgg ggtatagcca agcggtaagg caagggactt
      301 tgactccctc atgcgttggt tcgaatccag ctaccccagt ttagttttat acttaaagcc
      361 ggcgtggcgg aattggcaga cgcgctggac tcaaaatcca gtgtccgcaa ggacgtgccg
      421 gttcgacccc ggccgccggt atagtttaaa aatattgaaa aaacaaggtt tgtaaacctt
      481 gtttttttgt tttatgactt gatgtcagag gatcagattg gtcctctcta gatgttaaag
      541 gtaatgagaa tcttggcttc aaagctccta aatccaaagc attgcgcttg atgtctttga
      601 tcacctgtta gtggcgtgca gcttagcgtt tgaatttgga ataaggttgc tccaaggcat
      661 gtgtgatgtg agctttggat actaggactt ttagccaatt ctttgtgggt gagctttttc
      721 tttacgtttg gttttgatta atgtcgcaat atcagttatc atgtgttctc tggttaatga
      781 cgctttagca aatatcgtat tgtcttagca tcttgtttga gaaataaagc agactaatta
      841 agataagcga acccaaggca agtgttggga tggttacggt ataaaaagca ctgaaaactt
      901 caccaagatg ctcatcagga atctcagttc gtaaaatagg tttttgggta acatgcgtta
      961 ttccgagaaa tagacaggaa agaaaccaaa gaagcaacaa accaaaacgg ttggggacta
     1021 atgctgtaag gccaataccg gtgcccaaaa gggtagttgc tagccaaaaa gcttttccta
     1081 cacttaactt ttgcaagaca aggttagcaa caaaggttgt tcctaccagg gttccgatag
     1141 cacttacaga tactaagagg ccataaaaag ctgaattccc tacctctctt gctattaata
     1201 actgatagac atttaagctg gcaaaaagga aattagcgat agcacctccc aatgtgatgg
     1261 ctaacaccac tttattgtgc cagataaagc gcaagccact taaaaagtct gttcgttcat
     1321 ttgtttgttc aattatttct ttaaatgcta ttcttctaaa aaataggatt gaacctaaga
     1381 aggtaacgat attaatgaaa agcaaaggaa tgtagctgat cacagaaagc aaaaagccac
     1441 tgatggcagt aaaaacataa tctgttccat tataagccac tgacatatac atttctgctt
     1501 tagctagatc tttagtagga atgagtttag gtacaagagc atcttgaaca gtataggtat
     1561 tcaacccaac catagaagcc agaaaaacac aactaaaaat aatggttaag ctaagacttg
     1621 cgtgtatctc tcttaaggac attcctaaaa taatacctaa gacagccaat aattgggccc
     1681 actccagaat cactagcagg ttcttcttag ggtacgaatc aatctttttt ccaaagataa
     1741 aggagaaggt gtttggaata aaaatgagaa agttcaataa tccaacatac caagtactat
     1801 tagtggtttc tagtacatac caggacagca ctagggtata aatcgagtca ccgcaattgc
     1861 taatcagtcg ccccagaaat aaccggcaaa aatcattata tttccttaat atcatattgt
     1921 atcctttgat aaagagttta aacatctttt atattatagt atcagatgat aaaaaatcac
     1981 tgaatgatag ctgtgtttga tgtttgcaac attttaaaat atctttgcaa aaatcatacc
     2041 tagacacata caatcccaca taagttttaa aagcattcaa ttgcctttta agatctttat
     2101 gagtcatgtt tgtaaagata tcctcttgca acagatctct taatctctaa ttgtatccaa
     2161 taagaagcag ctttgtcaat acggaagccg aatagtcttt ttgcctttcc ttgtcagctg
     2221 ggcaatcatg agggctttgt gctttgatct tttgcatcta taaaagggtg aatctattga
     2281 tgaggtgtta tcggtagtgg ggcctactga tgtcaataac tgacgtcaga taattacctc
     2341 tttaattaga aaaaaaaaaa aacgaaacta cggagagaac ctaataactg gctatttctt
     2401 gctataagcc agcgtgttaa aatcttcttt gggagaaaat ttagaaaaaa ataatatttc
     2461 tatcactaag gagagaaaga tgacaactaa agaaaaacaa acaaaactaa tgcgcaggta
     2521 tggcattttc tcggtagtcg ttgccctaac agctctagca ggtctaggag cagctaatga
     2581 agttaaggca actgctaaaa aatctttaaa tgagttacct aatccagtag aaattattca
     2641 atataattca acaagaacta ctgatagaga agctagaaag tatcttaatc aattatatga
     2701 gtttttgaaa ccttatttag gaagtttaga agaagaagct caaaaaggag ggccacaagg
     2761 acctgtggga cctgctggtc ctagaggtga acgcggagaa ccaggaccta aaggagaccg
     2821 aggtcctgag ggccaaagag gtgagcaagg cccagcgggg cctattggac cccaagggcc
     2881 tcgtggtgac aagggtgaaa ctggagaaat tggacctagg ggagaacaag gtccgaccgg
     2941 tcctactggt aagccaggag agcgtggccc taagggtgac agaggcgaac gcggcgaaaa
     3001 aggcgagcaa ggccagcgtg gcgaaaaagg cgagcaaggc caacgtggcg aaaaaggtga
     3061 acaaggcc
//
LOCUS       DARYNN010000103         2928 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.104, whole genome shotgun sequence.
ACCESSION   DARYNN010000103 DARYNN010000000
VERSION     DARYNN010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2928)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2928)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2928
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.104"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            10..1431
                     /locus_tag="TVB59_001987"
     CDS             10..1431
                     /locus_tag="TVB59_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HEL1010825.1"
                     /translation="MFIIKGEVSRKDLIREIEKAIKSDELGAFIGAGLSIPAGFCSWK
                     ELLREPAEEIGLDVEKESDLVNLAQYYSNSKKRTSIDDLIKGQFSQLVKPTENHKLLS
                     QLPISTFWTTNYDKLIEKALENNMKKPYVKTKDEQLRGTNHNFDAIVYKLHGDVETPE
                     DAVITRSDYEEFGYNKRKLFREVLEGDLLTKTFLFLGFSFEDPNFNYVIGRLRVLLDE
                     KNTRKHYCIMKRVQDADEDYEYKKARQELQIEDLNRYGIFTYLVNKYDEITEILSTLV
                     DRFRRKTIFISGSAYSYSAYSQKTGENFIHKLSFELSKNGYHIVNGYGKGVGEFVLNG
                     VADYCLTHKSKINDFLTLMPFPQNSSLGIDLDKLYKENREQMIESCGIAIFLFGNKEA
                     EDIASGVMDEYELSKKHGLVCLPIEYTGGASKEIYDQTTQEISDKNTISAIEQANKQC
                     DGDIDMSVKNIVQAVKILNKEEF"
     gene            1432..1929
                     /locus_tag="TVB59_001988"
     CDS             1432..1929
                     /locus_tag="TVB59_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001129326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIR domain-containing protein"
                     /protein_id="HEL1010826.1"
                     /translation="MAKRQVFFSFHYDNDNWRAGQVRNMGKVDSSSTFSDNDWEEVKE
                     KTESKIKEWIDEQLNKRSCLVVLIGEKTANRKWINYEIRKAYELNKGIVGIYIHKLEN
                     SLGEQDDKGNNPFDYLTLEGEKLSKYVKCFDSNYSSSKYVYSDIKDNIEGLIEYGINH
                     KPSTW"
     gene            complement(1953..2351)
                     /locus_tag="TVB59_001989"
                     /pseudo
     CDS             complement(1953..2351)
                     /locus_tag="TVB59_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820672.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2431..>2928
                     /locus_tag="TVB59_001990"
     CDS             2431..>2928
                     /locus_tag="TVB59_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEL1010827.1"
                     /translation="MEYIERPKYLNHIEKFVDKPIIKILTGMRRVGKSTILMMIKDEI
                     LKHVPDEQKIYINFESLEFMSINEASFLASYISEKSKNLSGKLYYFFDEIQLVNNWEK
                     VVNGLRVDQDCDIYITGSNSNLISGELATLLAGRYIEFEIQPFTFGEFLKIFSDSNLT
                     KEALFD"
BASE COUNT         1095 a          332 c          555 g          946 t
ORIGIN      
        1 agggaggagg tgtttattat taaaggtgaa gtatccagaa aagatttgat tagagaaatt
       61 gaaaaagcta ttaaaagtga tgaattagga gcatttattg gagcaggatt atcaattcct
      121 gccggatttt gtagttggaa agaacttcta agagaacctg cagaagaaat tggattagat
      181 gttgaaaaag aaagtgattt ggttaacttg gctcagtatt attctaattc aaaaaagaga
      241 acatcaatag atgacttgat caaaggtcaa ttttctcaat tagtaaagcc tactgaaaat
      301 cataaattat tgtcgcagct gcccatttca actttttgga caacaaatta tgataagtta
      361 atagaaaaag ctttagaaaa taatatgaaa aagccttatg taaaaacaaa ggatgaacaa
      421 ttaagaggta caaatcataa ttttgatgcg atagtatata agctgcatgg tgatgtagaa
      481 actcccgaag atgcagtaat aacaagaagt gattatgaag agtttggata taacaaaaga
      541 aaattattta gagaggtttt agaaggagat ttgcttacta aaacatttct atttttggga
      601 tttagttttg aagatccaaa ttttaactat gtaattggaa ggttaagggt cttactcgat
      661 gaaaaaaata caagaaaaca ttattgtatt atgaaaagag tccaagatgc tgatgaggat
      721 tatgaataca aaaaagcaag acaggagcta caaattgaag acctaaatag atatggtatt
      781 tttacatatt tagtaaataa atatgatgaa atcaccgaaa tattgagcac tcttgtcgat
      841 agatttagaa ggaaaacaat atttatatct ggtagtgcgt actcctattc ggcttattct
      901 cagaaaactg gcgaaaattt tattcataaa ctatcttttg aactatcaaa aaatggttat
      961 catattgtga atggatatgg taaaggagtc ggtgaatttg tattaaatgg agttgcagat
     1021 tattgtttga ctcacaagtc caaaataaat gattttttaa cacttatgcc ttttcctcaa
     1081 aatagttcat taggtattga tttagataag ctatataaag aaaatagaga gcagatgatt
     1141 gaaagttgtg gtatagctat atttcttttt ggtaataagg aggcagaaga tattgcaagc
     1201 ggagttatgg acgaatatga gttatcaaaa aagcatggat tagtatgttt gcctattgaa
     1261 tatactggcg gtgcatctaa agaaatatat gatcaaacaa ctcaagaaat ttcagataaa
     1321 aatacaataa gtgcaattga acaggcaaat aaacaatgcg atggcgatat tgatatgtct
     1381 gttaaaaaca tagttcaagc agttaaaata ttaaataagg aggaatttta aatggcaaaa
     1441 agacaggtat tttttagctt tcattacgac aatgataatt ggagggcagg acaggttcgc
     1501 aatatgggga aagtagacag tagttctacc ttttctgata atgactggga ggaagtaaaa
     1561 gaaaaaactg aaagtaaaat taaagaatgg attgatgaac agttaaataa gcgttcatgt
     1621 ttggttgttt tgattggaga aaaaacagcg aacagaaaat ggataaatta tgaaataaga
     1681 aaagcatatg agttaaataa aggtattgtg ggaatttata ttcacaagtt ggagaattca
     1741 ctgggagagc aagatgataa gggtaataat ccttttgatt atttaacatt agaaggtgaa
     1801 aaactttcaa agtatgttaa atgttttgac tccaactatt catcaagtaa atatgtttat
     1861 agcgatatta aagataatat tgaaggttta attgagtatg gaataaacca taaaccatca
     1921 acttggtaat aaatgatgat ggagagaaaa aattatctct ccatctcctt acccatgtaa
     1981 attccataat tttttcgtat cttgtaaagt tcgtccataa tagattttga ggaagaatac
     2041 tcttgcataa gggtattctt tttttcttgc aatttatcaa gtctatctaa aataccctta
     2101 gaatttggca acttggaata tgatttttta agctctgaaa gggcattttc atataaggta
     2161 atctgagctt tgtactcttc aaaaaatgcc ttgtcagatg gacttgcctt atattctttg
     2221 tagtattgcc tgtatttttt aacagtgtga acttgctcca tagtggcaga aagctcctgc
     2281 atttccttat caatagcctt gatcttatcc tgtaaatttt gcctttcatc ggctgctttt
     2341 atgatatatt tcgattatat tcgaaaacaa tattggaaaa tatattttta tcgtgtataa
     2401 tataatcaaa gctaaagaga ggtgaatgat atggaatata ttgaacgacc caagtattta
     2461 aaccatatag aaaaatttgt tgataaacct attattaaaa tcttaactgg gatgcgaaga
     2521 gttggaaaat ctaccattct gatgatgatt aaagatgaaa ttttgaaaca tgtgccggat
     2581 gagcaaaaga tatatatcaa ttttgaatct ttggagttta tgagtataaa tgaagcgagc
     2641 tttttggcaa gttatataag tgaaaagtca aaaaatctaa gtggtaaatt atattatttc
     2701 tttgatgaaa tacagttggt aaataactgg gaaaaagtag ttaatgggtt aagagtagat
     2761 caagattgtg atatatacat taccggttca aattcaaatt tgatttccgg tgaacttgcc
     2821 acacttcttg caggaagata tatagaattt gaaatacagc catttacttt tggggaattt
     2881 ttaaagattt ttagtgattc aaatctaact aaagaagcac tttttgat
//
LOCUS       DARYNN010000104         2581 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.105, whole genome shotgun sequence.
ACCESSION   DARYNN010000104 DARYNN010000000
VERSION     DARYNN010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2581)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2581)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2581
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.105"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            <1..116
                     /locus_tag="TVB59_001991"
     CDS             <1..116
                     /locus_tag="TVB59_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018373723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HEL1010828.1"
                     /translation="RTVAKYIREQEKNDIALDKLSVKEYEDPFSDGSFKTR"
     gene            403..868
                     /gene="tnpA"
                     /locus_tag="TVB59_001992"
                     /pseudo
     CDS             403..868
                     /gene="tnpA"
                     /locus_tag="TVB59_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775157.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(1050..1205)
                     /locus_tag="TVB59_001993"
     CDS             complement(1050..1205)
                     /locus_tag="TVB59_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComC/BlpC family leader-containing
                     pheromone/bacteriocin"
                     /protein_id="HEL1010829.1"
                     /translation="MEKQNSLTQFQELNSSELNQITGGDWWSEILNFNRSQKYKHTSV
                     GSNNIIV"
     gene            complement(1299..2498)
                     /locus_tag="TVB59_001994"
                     /pseudo
     CDS             complement(1299..2498)
                     /locus_tag="TVB59_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842898.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
BASE COUNT          811 a          393 c          511 g          866 t
ORIGIN      
        1 aaaggacggt agcgaaatat attcgcgagc aggagaaaaa tgacattgca cttgataagt
       61 tgagtgttaa agaatatgaa gatccatttt cagatggcag ttttaaaaca agataaaagc
      121 ccgtttttac gggcattagt caagtaatca tagcactaac ctgaacgaag ttcagcgaac
      181 gtctttagac gtcgctggag agaaacggct tatagccggt gtacaagcca cccgttttta
      241 cgcgtggtta tgacttagtg actttagtcc gtttcgctcc gtaggtgcga aacaaaaatc
      301 ccccgctatg cgggtacgca tcgaacgtta tactacaaaa aaactccaaa cgcgctacaa
      361 tataggtgtt caagccaatt gtaaagcgaa aggagtaaaa atatggcaca aaagccccac
      421 agtttatcgc acacaaagta gcattgtaaa tatcacattg tgttcacccc taagtataga
      481 cgaaaagtaa tctataatca atatcgaggc agtttgggag aaatttttca aagattatgt
      541 agctataaag gtgtagaaat atatagaagg acatctgatg ccagatcacg tacacgtgtt
      601 agtaagcatt ccacccagaa taagtgtttc aagttttata ggatatttaa aaggtaagag
      661 tacgcttatg atgttcgaca agcacgccaa tctgaaatac aaatttggta atcgacactt
      721 ttgggcagaa ggctattata ttagtacggt tggattaaat gaagctacaa taaaaaaata
      781 tattcaagaa caagaaaaac atgacatagc actagataaa ctgagtgtaa aagaatatga
      841 ggatcccttt agagataagg gtaagtgata caaatacttc tttgagaggc aagtgacgag
      901 tcaatagcaa tgtggtttga acaaagtgaa agccagcgtc tttaggcgct ggctagttat
      961 atgggtttat agtccctatt caaaccacct gttggacggg tggttatgat ttctactaaa
     1021 aaaactatta ttacaatact aagtatatgt tagacaataa tattattaga acccacggag
     1081 gtatgtttat atttttgaga gcgattaaaa tttaatatct ctgaccacca atctccacct
     1141 gttatttgat tgagttcgga tgaatttagt tcttgaaatt gagtgagtga attttgtttt
     1201 tccatttgtg gacctccttc ttttttctaa tattataatt taagatcaat atattatttc
     1261 tctaaatcct aaatggtcat cgaaacgtcc ggaatggttt aatcatgatt tgacaacagt
     1321 ttattcttat aaaagtcgaa gtaggatttt ttagcgataa cacttgtaac acgaccctgt
     1381 gcaccatatt ttatcaagta gctatccttg gaagggagtt tggcaagagt tgtaatcttg
     1441 aaaagattac cttgttctgt ttttgttgct gttttatcaa tagtagaaat ttttccatta
     1501 acagtgatgg actgttttct cactttttga agatttagac gaacagtttg acctttttta
     1561 aggagagaaa cataatcaga agttacaaag tatgtaatca gagcttttct agtttgagta
     1621 atattaggat agattttggc aatatcacta ccatttggga taagactttt cccctcgtat
     1681 tcattattta gatgaataat cctggtttct ggtgctaaaa caacattagt gtctaactat
     1741 acacttgctt gttctagctg agctttaagt tcagtgattt gactgtcgat ggttgacagc
     1801 tgttgtgaag cattctgtag aaattgagtc ctcaagactt caactttggt ttctgaactg
     1861 ttatcgtatg ttgcactact accagtacct gctctttgaa tgctaagccc agagagggat
     1921 gattctaaac ctgaaatagt ctggttaatc tgagagataa actggttaga cgtggaagtt
     1981 tattcttctt gtgattgaga cagataatta ttgagaatat cttgatgagg attaccagtt
     2041 ggtaagattg tgttatgatt tgagatagct tgacgaagat cttcatattc tgaaatctgc
     2101 tggtttatag tattgatttg agtatcaatt gcagcaaggg tgttatttgc aagtgtggat
     2161 tgattggata cttctgtatt tattttagcg ataccaagtt taatctcttg agactgattt
     2221 ataaagttgt tgaaggtgtc agcaagacca aattcatcat tttgtggtaa gaggttcgtt
     2281 ccttgtttga gactttcttt caatgtctct aaaccaactt tttgtttatt caacgtattt
     2341 aattgtgatt ctagagaatt cttttgagaa ctctcaatgg tttctttata tttgattaaa
     2401 cgttttcctt ttttaacgag ttggttttct ttaagattat ttttaacgat agcattgttg
     2461 ctagttgact gtattgatgc aatgactttt gtaggcataa tttcacctcg tgacgatacc
     2521 gttacttctt tttgaccaag aaaagaaaat gaaagtaaaa atatgacgaa taatgttaat
     2581 g
//
LOCUS       DARYNN010000105         2475 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.106, whole genome shotgun sequence.
ACCESSION   DARYNN010000105 DARYNN010000000
VERSION     DARYNN010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2475)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2475)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2475
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.106"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            51..1004
                     /locus_tag="TVB59_001995"
     CDS             51..1004
                     /locus_tag="TVB59_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL1010830.1"
                     /translation="MNFEKIEQAYELILENSQLIENDLKTHIYDAIVEQNSFYLGAQG
                     ASPQVAKNIETLKALQLTKEEWRQAYQFVLIKAGKTEPLQANHQFTPDAIGFIMLYIL
                     ETLSSQESLDVLEIGSGTGNLAQTILNHSHKSIDYLGIELDDLLIDLSASIAEIMGSS
                     AQFIQEDAIRPQLLKESDLIISDLPVGFYPNDDIASRYQVASSDEHTYAHHLLMEQAL
                     KYLKKDGFAIFLAPVNLLSSPQSHLLKQWLKGYAQVVALITLPEAVFGNPANAKSIIV
                     LCKQSNRFAETFVYPIRDLKSVDNVRDFMENFKNWKRDNVI"
     gene            1064..2263
                     /locus_tag="TVB59_001996"
     CDS             1064..2263
                     /locus_tag="TVB59_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEL1010831.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEEKVLAQGIIERIGLTDSISTV
                     KYDGKKEEHILDIPDHTEAVKRLLNDLIHFGIIGTYDEITGVGHRIVAGGEYFKESVV
                     VDDKVVEQVEELAALAPLHNPGAAAGIRAFRKILPDITSVCVFDTSFHTTMQKHTYLY
                     PIPQKYYTDYKVRKYGAHGTSHKYVAEEAAKMLGRPLDELKLITAHVGNGVSITANYH
                     GQSVDTSMGFTPLAGPMMGTRSGDIDPAIIPYLIAQDPELKDAADVVNMLNKQSGLGG
                     VSGISSDMRDIEAGLQANNPDAVLAYNIFIDRIKKFIGQYFAVLNGADALVFTAGMGE
                     NAPLMRQDVVNGLSWFGMEIDPEKNVFGYRGDISTAASKVKVLVISTDEELCIARDVE
                     RLKQTIS"
BASE COUNT          730 a          440 c          557 g          748 t
ORIGIN      
        1 tggctagtgg tattcttttc atttcagcct tattttgata tgatagacgt atgaattttg
       61 aaaagattga acaagcctat gagcttatat tagaaaatag ccagctgatt gaaaatgatt
      121 taaaaacgca tatctatgat gctattgttg agcagaattc tttttatctg ggagcccaag
      181 gagcaagccc tcaggttgct aaaaatattg agacgttgaa ggccttgcag ttaaccaagg
      241 aggagtggcg ccaggcttat cagtttgttt tgatcaaggc tgggaaaaca gagccattac
      301 aggccaacca ccaatttacc ccagacgcga tcggctttat catgctttat attttggaga
      361 ccttgagctc acaagagtca cttgatgtgc ttgagattgg cagtggaaca ggtaatttag
      421 ctcaaactat tttaaaccac tcacataaga gcattgatta tttaggcatt gagcttgatg
      481 atttactaat tgatctatca gctagtatcg ctgaaatcat ggggtcatca gcccagttta
      541 ttcaagagga tgctatcaga cctcagctgt taaaagaaag tgatctcatc attagcgatt
      601 tgccagttgg tttttatcct aacgacgata ttgctagcag gtatcaggtg gctagctcag
      661 atgagcatac ctatgcccat catttactga tggagcaagc cttaaagtac ctgaaaaaag
      721 atggctttgc tattttctta gcaccggtaa atcttttgag cagcccacaa agtcacctct
      781 taaaacaatg gctgaagggc tatgctcagg ttgtggcctt gattactttg cctgaggctg
      841 tgtttggaaa tccagctaat gcaaaatcga ttattgttct ttgtaagcaa tcgaatcgct
      901 ttgcagaaac ctttgtttac cccattaggg atttgaaatc tgttgataat gttcgtgatt
      961 ttatggaaaa cttcaaaaat tggaaacggg ataatgttat ttaagagaat tttttgatat
     1021 aatagaaaag cattgcagaa aacgatttca agagaggtaa aacatgtcaa agacaattgc
     1081 aattaatgca ggaagctcca gcttaaaatg gcagctatat caaatgccag aggaaaaggt
     1141 attagcacag ggaattatcg aacgtatcgg tctgacagac tcaatctcta ctgttaaata
     1201 cgatggcaaa aaagaagagc atattcttga tattccagat catacagagg ctgttaagcg
     1261 cttgttgaat gatttgattc attttggcat tattggtacg tatgacgaga tcacaggtgt
     1321 tgggcaccgt attgttgcag gtggtgaata cttcaaggaa tctgtggttg ttgatgataa
     1381 ggttgttgag caggttgagg agttagcagc cttggcaccc ttgcacaatc cgggggcagc
     1441 agcaggtatt cgtgcctttc gtaagatttt gccggacatt acgagtgttt gtgtgtttga
     1501 tacttcgttt cataccacaa tgcaaaagca tacctacctt tatccaattc ctcaaaaata
     1561 ttatacagat tataaggttc gcaagtacgg ggcgcatggg actagccata aatatgttgc
     1621 tgaggaagca gcaaaaatgc tgggtcgccc tctagacgaa ttaaagctca ttacagccca
     1681 tgttggtaat ggtgtgtcta tcacagccaa ttatcatggt cagtcagtgg atacctctat
     1741 gggctttaca ccgcttgctg gtccgatgat ggggacacgc tctggtgata ttgatcctgc
     1801 tattattcct tatttgattg ctcaggatcc tgagctaaag gacgcagcag atgtggtcaa
     1861 tatgcttaac aagcaatctg gattaggtgg tgtgtctggt atttccagtg atatgcgtga
     1921 tattgaggct ggcttgcagg ctaacaatcc agatgccgtc ttagcttaca atatctttat
     1981 cgatcgtatc aagaaattta tcggacaata ctttgcggta ttaaatggtg cagatgcctt
     2041 ggtctttacc gcaggtatgg gtgagaatgc tcccttgatg cgccaagatg tcgtcaatgg
     2101 cttgtcatgg tttggtatgg aaattgatcc agagaaaaat gtgtttggtt atcgtggtga
     2161 tatttcaaca gcagcttcaa aggtgaaggt gcttgtcatc tcaactgatg aagagctgtg
     2221 tattgcgcgt gacgttgaac gcttgaaaca gactatatca taatctgata atatactctt
     2281 agctcagctg atcagtttta aagagtccaa aaaatacttt taattggtac cgacctccaa
     2341 aagttagact taaaggttta acgattggag gtcggtatta ttatatagcc aaatattctc
     2401 aagacaaaga cagccaaaaa atgagacggt cgtaaccgtc tcaaaaaagt ttaatttaat
     2461 taaaaacatt cattt
//
LOCUS       DARYNN010000106         2337 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.107, whole genome shotgun sequence.
ACCESSION   DARYNN010000106 DARYNN010000000
VERSION     DARYNN010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2337)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2337)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2337
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.107"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            <1..446
                     /locus_tag="TVB59_001997"
     CDS             <1..446
                     /locus_tag="TVB59_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="SPASM domain-containing protein"
                     /protein_id="HEL1010832.1"
                     /translation="IHNRLLVSDEKYAAHYNKLIEKFSCLGVQFLTSPFCHPWSLAIK
                     HGIEYHSPLYCPAQKTEFEIDMYGDVYPCPFLHDKIHLMGNLISDDFETIWYSGVEQL
                     NRRAWSSNDSCKNCKLFNDCGGGCYAMAFVSQLEYDKRCILHANQ"
     gene            433..693
                     /locus_tag="TVB59_001998"
     CDS             433..693
                     /locus_tag="TVB59_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEL1010833.1"
                     /translation="MQISKNWFIRFEPNFQTTQNTILFNKVSGELFEVTEVYYDCINS
                     LRIGVDFQALLMEKYAVNAGDVIDVEDTILKNLISLGVILNE"
     gene            686..1585
                     /locus_tag="TVB59_001999"
     CDS             686..1585
                     /locus_tag="TVB59_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002900052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1010834.1"
                     /translation="MSDITIRHVKKSFHHQVVLDVPSFDVKRGEIVAIVGANGAGKST
                     LIKMISGLMLQDTGSVLVYHHKNTSAAIHRDVKFVLESGRGYYEYLTANQNIDYFLHL
                     NNLSRSQVKEELAELCQKLAFNPYTDRLVSELSQGTRQKLSLIIALLCQPKVLCLDEP
                     TNGLDVVAKKQFATLLLELSQKKQTIILMTTHDIFFVKELSARICVMSKGKIKKQGSF
                     SEIFGENNTWMKYRIGIPKFEKAIFDQLFPFLAYQVEDERLVVEVTDSQTKHHIFEHF
                     EIIFFEEVEKSIEELLYEVITDD"
     gene            1575..2315
                     /locus_tag="TVB59_002000"
     CDS             1575..2315
                     /locus_tag="TVB59_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002909393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1010835.1"
                     /translation="MMIKEIQRELKRQLQEMMQFKFNLFFANFGILIMVSSYLHYFED
                     TQSQFLLLCLLFTWYFTSHSLTHPIFFIEDDLYDRTLISVIQSSKSVFHVLMLKIIVQ
                     LLVDLVKAIPIVIMLSLLNNIDFPESSLRVMGSFVACFLTVISTYGLGFCLSSLCFVF
                     NRTSSVTALISYFMLYFTGILTPLDGSLGLIGKMFPYYALRNAIMSPSYQSVCWIVAY
                     GMIYWSVGTLLFSRALTMAKKRGSLFHV"
BASE COUNT          719 a          338 c          467 g          813 t
ORIGIN      
        1 ctattcataa tagattatta gtatctgatg aaaaatatgc tgcacattat aataaattga
       61 tagagaaatt tagttgttta ggtgttcaat ttttaacatc acctttttgt cacccatggt
      121 ctcttgcaat aaagcatgga attgaatatc attccccact ttactgtcca gctcaaaaaa
      181 cggaatttga gattgatatg tatggagatg tctatccttg tccattctta cacgataaaa
      241 ttcacttaat gggaaattta atttctgatg attttgaaac tatttggtac tctggagtag
      301 aacagttaaa tagaagggct tggtcaagta atgatagttg taaaaattgt aaattattta
      361 atgattgcgg tggagggtgc tatgccatgg catttgtttc acagctagaa tatgataaga
      421 ggtgtatatt acatgcaaat cagtaaaaat tggtttatta gatttgaacc taattttcaa
      481 acgacacaaa atacgatatt atttaataaa gtaagcggag agctgtttga ggtaacagaa
      541 gtttactatg attgtatcaa ttctctgaga attggtgtcg attttcaagc tcttctgatg
      601 gaaaagtatg ctgtcaacgc aggggacgtg attgacgtag aagatacgat tttaaaaaat
      661 ctaatatcgc taggagtaat tcttaatgag tgacatcact atacgccatg tcaagaaaag
      721 ctttcatcat caggtagtct tagatgtgcc tagttttgat gtaaagcgtg gagaaattgt
      781 tgctatcgtt ggtgcaaatg gtgcaggtaa atcaactttg atcaaaatga tctctggttt
      841 aatgctgcaa gacacaggat ctgttttggt ttatcatcat aaaaatactt cagcagctat
      901 tcatcgtgat gtgaaatttg tcttagaaag tggtaggggc tattacgagt atctgactgc
      961 aaatcaaaat attgattact ttttacattt gaataacctg tcacgtagcc aagtcaaaga
     1021 agaattggca gagttgtgcc aaaaattggc ttttaatccc tatactgatc ggttggtttc
     1081 tgaattatcc caaggcacaa gacaaaaatt gtctttgatt attgctcttc tttgtcagcc
     1141 caaggttctg tgcttagatg agccaacaaa tggtctagat gtggttgcaa aaaagcaatt
     1201 tgcaaccttg ttgcttgagc ttagtcaaaa aaagcaaacg attatcctga tgacgactca
     1261 tgatatcttt tttgtaaaag agctatcagc aagaatttgt gtcatgagta aagggaagat
     1321 caaaaaacag gggagttttt cagaaatttt cggagaaaac aatacgtgga tgaaatatag
     1381 aatcggtatc cctaagtttg agaaggctat ttttgatcag ttatttcctt tcttagctta
     1441 tcaggtagaa gatgagagat tagtcgtcga agtgacagat agtcagacaa aacatcatat
     1501 ctttgagcat tttgagatta tattttttga agaagttgaa aaaagcatcg aagagctatt
     1561 atatgaggtt attactgatg attaaagaaa tacaaaggga gttgaaaaga caattgcagg
     1621 agatgatgca attcaaattc aatttatttt ttgcaaactt tggtattttg atcatggtgt
     1681 catcttatct tcactatttt gaagatacgc agagtcagtt cttgttatta tgtctattat
     1741 tcacttggta ttttacgagt catagcctca cacatccaat cttttttatt gaagatgacc
     1801 tttatgatag aacgttgatc agtgttattc aaagcagcaa gagtgttttt catgtcctca
     1861 tgcttaaaat tattgttcaa ctattggtgg atttagttaa ggcaatacct attgttatta
     1921 tgttatcact ccttaataat attgactttc cagaaagtag cttgagggtg atgggaagct
     1981 ttgttgcctg ttttttgaca gtcattagta catacggtct tggcttttgc ttatccagtc
     2041 tctgttttgt gtttaatcgt acctccagtg ttactgcgtt aatttcttat ttcatgctat
     2101 actttaccgg catactaacg ccattagatg gctcacttgg tcttattgga aaaatgttcc
     2161 cttattatgc tttgagaaat gctattatgt ctccttcata tcagagcgta tgttggattg
     2221 tggcttacgg tatgatatat tggtcggtcg gtacgttatt gttttctagg gcattgacaa
     2281 tggctaaaaa aagagggagt ctttttcatg tttagtgaaa tgaaacgata tatgact
//
LOCUS       DARYNN010000107         2216 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.108, whole genome shotgun sequence.
ACCESSION   DARYNN010000107 DARYNN010000000
VERSION     DARYNN010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2216)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2216)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2216
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.108"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(97..1722)
                     /gene="groL"
                     /locus_tag="TVB59_002001"
     CDS             complement(97..1722)
                     /gene="groL"
                     /locus_tag="TVB59_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880885.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEL1010836.1"
                     /translation="MAKDIKFSADARESMVRGVDILADTVKVTLGPKGRNVVLEKAFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPIGIRRGIEAATTTAVEALKAVAQPVSGKEAIAQVASVSSRSEKVGDYI
                     SEAMERVGNDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDNEKMVADLENPFI
                     LITDKKISNIQDILPLLEEVLKTSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAVLTGGTVITEDLGLELKDATMAALGQAAKVTVDKDNTVIVEGA
                     GSSEAISNRVSLIKSQLETTTSEFDREKLQERLAKLAGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALINVMDKVAALELDGDAATGRNIVLRALEEPVRQ
                     IAYNAGYEGSVIIDKLKNSAAGIGFNAATGEWVDMIATGIIDPVKVTRSALQNAASVA
                     GLILTTEAVVATKPEPAAPAMPQGMDPGMMGGF"
     gene            complement(1790..2077)
                     /gene="groES"
                     /locus_tag="TVB59_002002"
     CDS             complement(1790..2077)
                     /gene="groES"
                     /locus_tag="TVB59_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEL1010837.1"
                     /translation="MLKPLGDRVVLKFEAEKEQTVGGFVLAASHKEATKVGTVVAVSE
                     TGIRTITGDIVPPSVAVGDKVLVEYGSGLEVKDGDQELVICREADILAVLA"
BASE COUNT          626 a          557 c          389 g          644 t
ORIGIN      
        1 agggataatc atatcacctt aacgtcaggg gagtctttat aagttatttt tatatcctat
       61 gacagacaca ctagtctatc ctaacaggcc ttcttgttag aagccaccca tcatgcctgg
      121 atccattcct tgcggcattg ctggtgcagc aggctctggc ttagtggcaa caacagcttc
      181 ggtggtcagg ataagacctg caacagaggc tgcattttga agtgctgaac gtgttacctt
      241 gactggatca atgatacctg tagcaatcat atcaacccat tcaccagttg ctgcattaaa
      301 accaatacca gcagcactat ttttcagctt atcaataatc actgaacctt catagccagc
      361 gttgtaagca atttgacgca caggctcttc aagcgcacga agcacgatat tgcgaccagt
      421 tgctgcatca ccatcaagct caagggctgc aaccttatcc atgacattga taagagcagt
      481 accaccacct gcaacgatgc cttcttcaac cgcagcgcgt gttgcattta gcgcatcctc
      541 aatacgaagc ttcatttctt ttagctcggt ttcagtagct gcacccacct tgataactgc
      601 aacaccacct gctaattttg ctaagcgctc ttgtaatttt tcacgatcaa attcagatgt
      661 ggttgtttct aattgtgatt tgatcaggct aacgcggttt gaaatagctt ctgagctgcc
      721 tgcaccttct acaatcactg tattatcctt gtcaacagtt actttagccg cttgtccgag
      781 ggcagccatt gtagcatcct tcaattcaag accaagatcc tcagtgatga ctgtaccacc
      841 agttaagaca gcaatgtctt caagcatcgc tttacgacga tctccaaagc caggcgcttt
      901 aaccgctaca acattgaagg taccacgaat tttattaagc actagggtcg gaagggcttc
      961 gccatcaaca tcatcagcaa tgatcaacaa tggacggcta gtcttaagca cctcctcaag
     1021 caatggaaga atgtcttgga tattagaaat tttcttatca gtaatcagga taaatgggtt
     1081 ttcaagatca gcaaccattt tttcattgtc agtgaccatg tattgtgaca aatagccgcg
     1141 gtcaaactgc attccctcaa caacctcaag ctctgtttcc ataccacgtg attcctcaat
     1201 agtaatcaca ccatcatttc ccacgcgctc catagcttca gaaatatagt caccaacctt
     1261 ttcagaacgt gatgacaccg aagctacttg agcaatagct tcttttccag atactggttg
     1321 agcaacagcc tttaaggcct cgacagctgt cgttgtcgct gcttcaatcc cacgacgaat
     1381 accaattggg ttagcacctg ctgttacatt tttaagccct tcacgcacaa tcgcttgggt
     1441 caaaacagta gctgttgttg tcccgtcacc agcaatatca tttgtttttg aagctacctc
     1501 tgatacaagc ttagccccca tattttcaaa atgatcttct aattcaatct ctttggcaat
     1561 cgttacacca tcatttgtga tcaaaggaga accaaaggcc ttttcaagga ctacattacg
     1621 ccctttaggg ccaagggtta ccttaacggt atccgccaaa atatcaacac cacgtaccat
     1681 gctttcacga gcatctgctg aaaattttat atcttttgcc atgttatttc ctctattcct
     1741 atttgaatgt atatctgtta atcctacctg aaatgatagg gattcacaat taagctaaaa
     1801 ctgcaagaat gtcagcttca cgacagatga caagctcttg atcgccatct ttaacctcta
     1861 agcctgatcc atattcaacc aaaaccttgt cacctacagc cacacttggt ggaacaatgt
     1921 ctccagtaat agtacgaata cctgtctcac taacagctac aactgtccct actttagtgg
     1981 cttctttgtg actagcagca agaacaaagc caccgacggt ctgctctttt tctgcttcaa
     2041 attttaggac cacacgatct cctaacggtt ttaacatgaa tagtacctcc aataatgact
     2101 agattatcta ttttgttagc actcttgttt tatgagtgct aactttcttc tctattttat
     2161 cacttggtca aaaatagtca agaaaaaaag tctaggaaaa aagaaaagac ccagct
//
LOCUS       DARYNN010000108         2131 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.109, whole genome shotgun sequence.
ACCESSION   DARYNN010000108 DARYNN010000000
VERSION     DARYNN010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2131)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2131)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2131
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.109"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            130..498
                     /locus_tag="TVB59_002003"
     CDS             130..498
                     /locus_tag="TVB59_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HEL1010838.1"
                     /translation="MANRTRNNGIYLMLSDDELEILNKKYELSGCKSLRQFIMKCILE
                     KDIFVLDMKVFKEMSTNIGRITGSINQIAKRVNSTAVIYKDDINDLKKLLEKQGKDIY
                     FLRKKLYELGNFGTSGTEEI"
     gene            498..1871
                     /locus_tag="TVB59_002004"
     CDS             498..1871
                     /locus_tag="TVB59_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014262108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEL1010839.1"
                     /translation="MAVTKIHPIEKTLYLALDYIMNEDKTDEKILISSFGCNPKTAHL
                     EFEHTKKECNSKAKILARHLIQAFAPGETTPEQAHQIGLDLCERVLRGKYEYVLTTHI
                     DKGHLHNHILFNNVSFETGKAYQSNKRSYHQIRTVSDDLCRENGLSVIDENYKKFKNR
                     YSTNGKTYMEYTEFKKGNSWKNKLQLTIDKAVLKSKTYEEFLKTMEDFGYEIKIGKYL
                     SFRHKDKRDKGRFTRAKASTLGEDYTKERIKERIEDSNKQNIYVNQEYHYEKRSYKKP
                     DTIVDMKNNEKVKSSKGYEVWAGKHNMKTMASALNEMRKSGINSYEELDLKLKKVASD
                     RQQLLDHIKQIEKEMKSIYSVIENKNTISENQLTYDMYIKDKENKAFYEEYKSQIIAY
                     ETAMKSLKNSKLQTLSIKNLSDKYMLLEQEKTTLMGEYSSQNSMLRKLQQAKKNTDLY
                     LDNSLEK"
BASE COUNT          873 a          310 c          350 g          598 t
ORIGIN      
        1 ttatctctta acaggagatt tcttgacaaa gaaatataaa aatgaaacct gtatatcaag
       61 tttgtacttg attttacagg ttttttcttt tgtaaacttt taatacatct atgaattgga
      121 ggttatacta tggcaaacag aacaagaaat aatggaatat accttatgct ttctgatgat
      181 gaacttgaaa ttttgaataa aaaatatgaa ctgtccggtt gtaaaagttt aagacagttt
      241 attatgaagt gcatccttga aaaagatatt tttgtactgg atatgaaagt gtttaaggag
      301 atgtctacaa atatcggaag gattacaggt agcatcaatc agattgcaaa aagggtaaat
      361 tcaactgctg taatttacaa agatgacatc aatgatttga aaaagctctt ggaaaaacaa
      421 ggaaaagaca tctactttct tcgtaaaaag ctatatgaat tagggaattt tggaacaagt
      481 ggtacggagg aaatctaatg gcagttacaa aaattcatcc gatagaaaaa acactttatc
      541 tagcattaga ctatattatg aatgaagata aaaccgatga aaaaatcctt atctcctctt
      601 ttggctgcaa tcccaaaaca gcccatcttg aatttgaaca tacaaaaaaa gaatgtaatt
      661 ccaaagcaaa aatcttggca aggcatctaa ttcaagcctt cgctccagga gaaactacac
      721 ctgagcaggc acaccaaatc ggactggatc tatgtgagag agtcttgagg ggaaagtatg
      781 aatatgtcct tacaacacat atcgacaagg ggcatctaca caatcatatt ctgtttaaca
      841 atgtcagctt tgaaacagga aaggcatatc aaagtaataa gagaagttat catcaaatcc
      901 gaacggtcag tgatgattta tgtagagaaa atggcttgtc agttattgat gaaaactaca
      961 aaaaatttaa aaacagatac tctacaaatg gtaaaaccta tatggaatat accgaattta
     1021 agaaaggaaa ctcttggaag aataaactac aacttactat tgataaagct gttttaaaat
     1081 ccaaaactta cgaggaattt ctaaagacaa tggaggattt cggttatgaa atcaaaatag
     1141 gaaaatacct ttccttccga cataaagata aaagagataa gggaagattt accagagcga
     1201 aagcatctac tttaggggaa gattatacaa aagagagaat caaggaacga atcgaagatt
     1261 caaataagca aaatatttat gttaatcagg aatatcatta tgaaaaacgc tcctacaaga
     1321 aaccggatac tattgtagat atgaaaaaca atgaaaaggt aaaatcatct aagggatatg
     1381 aagtatgggc aggtaaacat aatatgaaaa ctatggcatc tgccttaaat gaaatgagaa
     1441 aatcaggtat taactcctac gaggaattag atttaaaatt aaagaaagtg gcatcagata
     1501 gacaacaatt attggatcat ataaagcaaa tagaaaaaga aatgaagtcc atttattctg
     1561 taatagaaaa taaaaatacg atttctgaaa atcaactaac ctatgatatg tatataaaag
     1621 ataaggaaaa caaagccttt tatgaagaat ataaatcaca gatcatcgcc tatgaaacag
     1681 ctatgaaaag tcttaaaaat tcaaagcttc aaacattgag cattaaaaat ttatctgata
     1741 aatatatgct tttagaacaa gaaaaaacta cacttatggg agaatattcc tctcaaaact
     1801 ctatgcttcg caagctgcaa caagcaaaga aaaatacaga tttatacctt gataacagcc
     1861 ttgaaaaata aaaaaaagaa ggagattatc cctacccata tttcaggtaa gaataatctc
     1921 cttacttgct ctcaaattga taaaagtata ttttctacaa tatttcacaa taatattttc
     1981 ttatttgtcg tgtgtttcta caagatagtc ctctcttctt ttccacacaa ccaaagaaat
     2041 aatagcgatt ataatataat tgaccacttg attcataaag ctgttgttta aaagtggcag
     2101 aaaataggat ttttcagttg taataaatcc a
//
LOCUS       DARYNN010000109         2069 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.110, whole genome shotgun sequence.
ACCESSION   DARYNN010000109 DARYNN010000000
VERSION     DARYNN010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2069)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2069)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2069
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.110"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            64..465
                     /locus_tag="TVB59_002005"
     CDS             64..465
                     /locus_tag="TVB59_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003033322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEL1010840.1"
                     /translation="MAVKRKYIYVKGQKIYVPDEVYRAYKKGLNHETHLKRLDRKHGV
                     FRFGDFNTSIVDIADNTVDVEKIIETKMLIEDLYYALDSLNDEERKLIEALYFDDKTL
                     TEVAKQRDTNPMKISRLRNKILEKLRKFLDK"
     gene            921..1088
                     /locus_tag="TVB59_002006"
     CDS             921..1088
                     /locus_tag="TVB59_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000332792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEL1010841.1"
                     /translation="MCEEHNIDIKMEIDKKDKQTINQIDGWNIEVKFNENGLSLENLV
                     EEYIKEKFSVY"
     gene            1187..>2069
                     /locus_tag="TVB59_002007"
     CDS             1187..>2069
                     /locus_tag="TVB59_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019115678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEL1010842.1"
                     /translation="MFKDSVNKENIAVMYLRLSKEDGEKTESNSISNQREMINSYAKK
                     NQFIIIKEYVDDGYSGATFDRPNFKEMINDAYDKKFDTIIVKDLSRFGRDYIEAGKYI
                     QRIFPENGIRFISVNDNYDSKSADMNDTHLILPIKNFINDSYCRDISNKVKSSQKIKR
                     EKGDFISAFAPYGYKKSDENKNKLVVDEQAAPNIKNIFDMKLLGYSSKAIADELNHLG
                     VLTPRKYKESQGFKCNGFQNIKGGNWSAKSVNRIIENEVYIGNTLQGKSVTLNYKNKK
                     QIEREKEDWIRVENTHDA"
BASE COUNT          847 a          225 c          400 g          597 t
ORIGIN      
        1 aggtcctcct tttttattca aaaaataagt ttgaaatttt tgataaaaag gagggcttta
       61 caaatggcag ttaaaagaaa atatatctat gtaaaaggtc aaaagattta tgtacctgac
      121 gaagtgtata gagcatataa aaaagggctt aatcatgaaa ctcatttaaa gagattggat
      181 agaaagcatg gcgtatttcg ttttggagac tttaacacaa gtattgtaga tattgcagat
      241 aatactgttg atgttgaaaa aatcattgaa acaaaaatgc tgatagaaga tctgtattat
      301 gcattagaca gtttaaatga tgaagagaga aaactaattg aagcactata ttttgatgat
      361 aaaactctca cagaagttgc aaaacaaaga gacacaaatc caatgaaaat cagtagatta
      421 agaaataaga ttttagaaaa gctgagaaaa tttttggata agtaaattaa gtagagggca
      481 gggaaacatc tctgtcctct atttttgaaa atttttcaaa aatagtgtta aaagttgtcc
      541 tgaaagtaag gtttatatat agagggactt ttattacctc gttatatata gatttgatct
      601 ttgacaactg aatagaccaa gacaagactt taaccagtag tggagcaatt tataaactta
      661 cgccaagata aacctgctaa gttaaattga tttaaatgaa tacctacatt tgtagaggat
      721 ataaggtttg gagcgataaa taagtctgta taaaaagagg gtggcaactc ttgtgcgatg
      781 atactaatgg ggataatgat acttctacag ttgaagccgg ctcatcttga aaagaggcgg
      841 aggtgaaatt cctatgtagc agccaatgca cttgtcaatg tcataaaact taaaaatatt
      901 gaagataagg agaagatatt atgtgtgaag aacataatat agatattaag atggaaatag
      961 ataaaaaaga taaacagaca ataaatcaaa ttgatggttg gaatatcgaa gttaaattta
     1021 atgaaaatgg attgagctta gaaaatttag tagaggaata catcaaagaa aaattttctg
     1081 tctattaggg gctgacaaaa aatataagga gcgttataat atttttgtgg aagcctaacc
     1141 ttggttcgat ttattgtatg taaattgaat ttaaggaggc ttttttatgt ttaaagacag
     1201 tgtaaataaa gaaaatattg cagttatgta tttgaggctt tcaaaagaag atggagaaaa
     1261 aacagaaagt aattctatat ccaaccaaag agagatgata aattcttacg caaagaaaaa
     1321 tcaatttata attatcaaag agtatgttga tgacggatat tcaggagcaa cttttgatcg
     1381 tcctaatttt aaagaaatga taaatgatgc ttatgataag aaatttgata cgattattgt
     1441 aaaagaccta tcaagatttg gaagagatta tatagaagca gggaaatata tacaaagaat
     1501 atttccggaa aacgggataa gatttatatc tgtaaatgac aactatgata gtaaaagtgc
     1561 ggatatgaat gatacacatc taatactccc tataaaaaac tttatcaacg acagctattg
     1621 ccgagatatt tccaataaag taaagagttc tcagaagata aaaagagaaa aaggggattt
     1681 tatcagtgct tttgcacctt atggatataa aaaatctgat gagaataaaa ataagttggt
     1741 ggttgatgaa caagctgctc ctaacatcaa aaatatattt gatatgaagc tcttgggata
     1801 ttcctcaaag gcaatcgcag atgaattaaa tcacttaggt gttttgactc cgaggaaata
     1861 taaagaaagt caaggcttta agtgtaatgg atttcaaaat ataaaaggtg gtaattggtc
     1921 agcaaagtca gtaaacagaa ttatagaaaa tgaagtatat attgggaaca ccttgcaagg
     1981 caaaagtgtt accttaaact ataaaaataa aaaacagata gaaagagaga aagaagattg
     2041 gataagagta gaaaatactc atgatgcaa
//
LOCUS       DARYNN010000110         1965 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.111, whole genome shotgun sequence.
ACCESSION   DARYNN010000110 DARYNN010000000
VERSION     DARYNN010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1965)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1965)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1965
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.111"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(<1..921)
                     /locus_tag="TVB59_002008"
     CDS             complement(<1..921)
                     /locus_tag="TVB59_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1010843.1"
                     /translation="MFKTTVRILNWSRKYSTRIKKGFILSFLNSVFIAMPIMLSIYVF
                     NLVLGNYYGSTTYGNKEIAIVTTIMIGLVLGRYITAYFKSVNQDSIGYEMSADERVQI
                     GDILKRVPLGFFQENNPGELTTAVTTDLSFFENYSMKMIDIVINGYIMALVMIISISF
                     LSWELGVVAVSGVVLSYFCLLLLRKHSEKNSVFYLNAQSKLVESTMELIIGLPIVKAF
                     NKGDISLKNFNAAILSSKKVNLRIEKEYTPFNCLHLFSLKLASMCIVIIAGMMAINNK
                     IDISIMIAIFIFSFIMFSSVENINSATHVLE"
     gene            complement(926..>1965)
                     /locus_tag="TVB59_002009"
     CDS             complement(926..>1965)
                     /locus_tag="TVB59_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1010844.1"
                     /translation="KSTWSIMNFASSILPSTFLGTLPVGMILYLNGTLTPAEFCICLM
                     LSLGIVIPLTQFTNYVNLLKSIEYAVKDINEILCIPNLISIDNNEHICTTNIKFNNVF
                     FSYDNENSVLENINIEIPQNSFTAIVGPSGSGKSTIIKLISRYWDVCGGEITIGGKNV
                     KDISLNQLNDLIGYVSQNNFLFNESIMENIRMGNPDASDEEVIEVSKICACHDFIMEL
                     EEGYNSNVGSLGSKLSGGQRQRISIARMMLKNAPIILLDEATAFIDPDNEEKIQGAIN
                     VLTKNKTLIVVAHRLSTIKNADKIVVLKNKTIFDTGTHDELLEKCDLYKNMWLSHIGA
                     KSKSIVSNIGG"
BASE COUNT          697 a          338 c          222 g          708 t
ORIGIN      
        1 ttccaaaaca tgagttgcag aatttatatt ttccactgat gaaaacataa tgaaagaaaa
       61 tataaatatt gcaatcataa tagagatatc tattttatta tttatagcca tcattccagc
      121 tattattaca atacacattg atgctaattt taatgaaaat aaatgtaagc aattaaaagg
      181 tgtatactct ttttctattc tcaaattcac ttttttacta cttaaaatag cagcattaaa
      241 atttttaaga cttatatcac ccttgttaaa agctttaaca ataggaagtc ctattataag
      301 ttccattgta gattcaacta atttactttg tgcattaaga taaaaaacag aatttttctc
      361 agaatgttta cgaagtaaca ataaacaaaa atacgaaagt actactccag aaactgctac
      421 aacacccaat tcccaagata aaaaagaaat actgattatc ataacaagtg ccattatata
      481 accgttaata actatgtcta tcattttcat cgaataattt tcaaaaaaag acaaatctgt
      541 ggttacggca gtagtcaatt ctcccggatt attttcttga aaaaatccca atggtactct
      601 ttttaatata tcaccaattt gtactcgttc atcagctgac atctcataac caatactatc
      661 ctgatttaca gacttaaaat aagcagttat atatctccct aaaaccaatc caatcattat
      721 agtagtcact atggctattt ctttatttcc atatgttgta ctcccataat agtttccaag
      781 aacgagatta aaaacatata ttgatagcat tattggcatt gcaataaaaa cagaatttaa
      841 gaaagataat ataaaccctt tttttattct cgtactatat tttctagacc aatttaatat
      901 tctgacagtc gttttaaaca ttgcactaac ctcctatatt agatacgatt gatttcgatt
      961 tggctcctat atgcgataac cacatatttt tatataaatc acatttttca agaagttcat
     1021 cgtgtgtacc tgtatcaaat atagttttat tttttaaaac cacaatttta tctgcgtttt
     1081 ttatagttga taatctatgt gctacaacta ttaaagtctt attttttgtc aaaacattaa
     1141 tagcaccttg tattttttct tcattatctg gatctataaa tgctgtagct tcatcaagca
     1201 atataatagg agcatttttc aacatcattc tcgctataga aatcctttgc ctttgtccac
     1261 ctgaaagctt acttccaaga cttcccacat tggaattata tccttcttca agttccataa
     1321 taaaatcatg gcaagcgcaa atctttgata cctctataac ttcttcgtca cttgcatcag
     1381 gatttcccat ccgtatattt tccataatac tttcattaaa tagaaagtta ttctgcgata
     1441 cataaccaat taaatcatta agttgattta atgatatatc tttaacattt tttccaccta
     1501 ttgtaatttc cccaccacaa acatcccaat atcttgaaat aagttttatt attgtggatt
     1561 ttcctgaacc tgatggtcca actattgcag taaaagaatt ttgaggtatt tctatattta
     1621 tattctctag gacactattt tcattatcat aagagaaaaa aacattatta aactttatat
     1681 ttgttgtaca aatatgttca ttattatcga tagaaataag attaggaata catagaatct
     1741 catttatatc ttttacagcg tactctatac tttttaacag attgacataa tttgtaaatt
     1801 gagtgagagg aattactatt ccaagagaaa gcattagaca tatgcaaaat tcagcaggtg
     1861 tcagtgttcc gtttaaatat agaatcatac ccacaggtaa tgttcccaaa aatgttgatg
     1921 gcaaaataga acttgcaaaa ttcataatac tccaagttga tttaa
//
LOCUS       DARYNN010000111         1942 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.112, whole genome shotgun sequence.
ACCESSION   DARYNN010000111 DARYNN010000000
VERSION     DARYNN010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1942)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1942)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1942
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.112"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(<1..443)
                     /locus_tag="TVB59_002010"
     CDS             complement(<1..443)
                     /locus_tag="TVB59_002010"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010845.1"
                     /translation="MSVQVALKKALKPTWKRKLRQSWSIQRSTHLFSWYMVKHMDLTS
                     FRYVETNDYVLPEYGFKIHISGTFQNYKAIFSVVFPYLKCHHISFKYLKDEKMILENV
                     SDMEDPSESGKFITIYPRDREHCKQLLSDLYELIPVETEGVYILS"
     gene            complement(859..1725)
                     /locus_tag="TVB59_002011"
     CDS             complement(859..1725)
                     /locus_tag="TVB59_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
                     /protein_id="HEL1010846.1"
                     /translation="MQYMGEMFKLLRTSRHISLKEATGDDFSHSMLSRFENGESDITI
                     SKLLVGLSNIRTELNEFIYLANGFKPSPYAVLKQEIWEAISKKDLSSLHQLYTKELEQ
                     YHLYKKDIYFLNALMIKSQMLFLDENIKMTPDEQSFLYDYLFSVEIWGIYELQLFSDI
                     SPLLSLDVYLRYTREMLGRVDFFEELWQHRNLVHSILLNGLFKATQEKRLGIAAYFDK
                     MINNHFFEENDTYLRIVYMIADGQHLYCKGEKELGLKQINDAIHILKALNCDESAAYY
                     SDSLEKWLKEVE"
BASE COUNT          610 a          376 c          269 g          687 t
ORIGIN      
        1 tcactaagta tatagactcc ttctgtctca acaggtatca attcatacaa gtcacttaat
       61 aattgtttac agtgttctct atctctggga taaattgtga tgaatttccc agattccgaa
      121 ggatcttcca tatcggatac attttctaaa atcatttttt cgtcttttaa atatttaaaa
      181 gaaatatgat gacattttaa atacggaaat actacagaaa aaattgcttt atagttttga
      241 aatgttcctg aaatatgaat tttaaatcca tattcaggta aaacataatc attcgtctct
      301 acatatctaa agcttgtcag atccatatgc ttcaccatgt accagctgaa taaatgggta
      361 cttctctgga tgctccatga ttgtcttaac tttcttttcc acgtaggctt caaagctttt
      421 ttcaaagcta cttgaacact cacgagaatc ttctttatag atacattttt aagtaatcat
      481 tggttttctc atagcaatac atctcctcag tcttattagt ataaaactaa aaacgctcac
      541 attaacaggt ctttttgagc gtttttagta ggactagtta ctaaattatg gtttgtagat
      601 tggacatttc caagtcacaa caaagccttt cactggcgca aagcatctac tagcctcgta
      661 tgcaaattga gtcatgtttg tgatctcctt tcattcttga tgagtctagt gtatcatcaa
      721 aaaccgtacc aaagctaaac tgttcatatg ttcaaatcat ggttttgaca ttaatcaaaa
      781 aacagtagct caaaaagcca ctgtttgcta ctagctaagc atctaaacca ttttgcttat
      841 caatgcttta agttgcattt attcaacttc ctttaaccat ttctctaaac tatctgaata
      901 ataggctgca ctttcatcac aatttaatgc ctttaagatg tgtatggcgt catttatttg
      961 ctttaagcct agttcctttt cccctttaca atataggtgc tgaccatcag caatcatata
     1021 aacaattctt aagtaggtgt cattttcttc aaaaaaatga ttgttaatca ttttatcaaa
     1081 atatgcagct atacctagcc ttttttcctg agtagcttta aacagcccat ttaataaaat
     1141 gctgtgcact aaatttcgat gctgccaaag ctcctcaaaa aagtctactc ttcctagcat
     1201 ttctcgagta taccgcaaat acacatccaa ggataataag ggagaaatat ctgaaaataa
     1261 ttgtaattcg tatattcccc aaatctccac tgaaaacaaa taatcatata aaaagctttg
     1321 ctcatctgga gtcattttga tattctcgtc taaaaagagc atttggcttt taatcatcaa
     1381 agcatttaaa aaatagatat cctttttgta taaatgatac tgctccagct cttttgtata
     1441 caattgatgt aagctggaca ggtctttttt tgatatggcc tcccagatct cttgctttag
     1501 gacagcatat ggggaaggct taaagccatt tgctagatag ataaattcat tgagctctgt
     1561 ccgaatattg ctaagtccaa ccaatagctt tgagattgtt atatcggatt caccattttc
     1621 aaatctgctt aacatcgagt gagaaaagtc atctcccgtc gcttccttta acgatatgtg
     1681 tcgcgatgtc cgcagtaatt taaacatttc tcccatatat tgcatatcaa tacctcttca
     1741 atctttcatt ttagtatagt atataacctt aaaaatgtaa atccagtctt gattgcataa
     1801 acctttaatt caacgtttga tgctactaaa tatcctattt ttctgaagta gatcctcatc
     1861 tttatgctat aagcacttgc tgcgttttag aaaatgggct aaatcagcta tactcctttt
     1921 taataacaaa aaagccttat tt
//
LOCUS       DARYNN010000112         1912 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.113, whole genome shotgun sequence.
ACCESSION   DARYNN010000112 DARYNN010000000
VERSION     DARYNN010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1912)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1912)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1912
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.113"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(<1..358)
                     /locus_tag="TVB59_002012"
     CDS             complement(<1..358)
                     /locus_tag="TVB59_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HEL1010847.1"
                     /translation="MNIELKENLEKNYDDNVWEHVTLGEFVANCAETYKDKTAIVDGE
                     LNLSYDELDKLSNKYANGLLKAGFKKGDKIVLQLPNCYEFIVISFAMFKTGIIPIMSL
                     PAHRKNELKGIIEKSEA"
     gene            complement(367..1050)
                     /locus_tag="TVB59_002013"
     CDS             complement(367..1050)
                     /locus_tag="TVB59_002013"
                     /inference="COORDINATES: protein motif:HMM:NF013786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase superfamily
                     protein"
                     /protein_id="HEL1010848.1"
                     /translation="MKIYRIEISDKKELRSLIDISRLLIFFDMVLVTSNTSEFMIKDL
                     KNFLKEEEIEKLDAYKSEVAKINFAVSRSLLNKVFEMILGVPIENIVSFRDKHNKPYI
                     ENKSGVKFNISHTDGFVVIGFSKKELGIDIEKVNDGFAFEDILENCFTSREIKNIGSN
                     IPMFYRYWTAKEAYLKYEGYGLIRNPKEIEVIYIDNQRIKIEDKVKRSNKDLIAFSIS
                     SKYFGAICI"
     gene            complement(1037..1786)
                     /locus_tag="TVB59_002014"
     CDS             complement(1037..1786)
                     /locus_tag="TVB59_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HEL1010849.1"
                     /translation="MGMWFEYVNKEMENTKASLFVFPFAGGGVSSFRRWGNQFKDINL
                     FVAQYPGRENRFSEKAISNIEELVKGLFEDLKMTFDFNSPYYFFGHSMGTKIAYELAL
                     KIKENGLPNPNGIIISAGRAPCYKEPNPIYHLDDEGFIEGLRRYDGTPNEILDNKDLI
                     GIFLPTLRADFIIDEDYQDTKGEKLNSKILGLMGDIDEEMELEELLKWQDYTTKEFSY
                     RYINGKHMFVNTSPESVIKAIEEFVYSNENI"
BASE COUNT          600 a          385 c          190 g          737 t
ORIGIN      
        1 ccgcctcaga cttttctata atacccttta attcattctt tcgatgtgca ggcaaactca
       61 taatcggaat aattcctgtt ttaaacattg caaaagatat cactataaat tcataacaat
      121 ttggaagctg taatacaatc ttatctcctt ttttaaaacc tgctttaagt agtccattag
      181 catacttatt cgaaagttta tcaagctcat cataagataa gtttaattct ccatctacaa
      241 tcgctgtttt atctttatac gtttccgcac agttcgcaac aaactctccc aaggtcacat
      301 gttcccaaac attgtcatca taattttttt ctaaattttc tttcaattct atattcatac
      361 ttcctcctat atgcaaattg ctccaaaata tttcgatgaa atgctgaatg ctatcaaatc
      421 tttattactc ctttttacct tatcttcaat ttttattctc tgattgtcga tataaataac
      481 ttctatttct ttcggatttc ttataagacc atatccttca tattttaggt aggcttcttt
      541 tgctgtccaa tatctataaa acattggtat attactgcct atattcttaa tctctctgga
      601 tgtaaagcaa ttttcaagta tatcttcaaa cgcaaagcca tcattcactt tttcaatgtc
      661 tattccaagc tctttctttg aaaaaccaat tactacaaat ccatccgtat gtgaaatatt
      721 aaatttcact ccacttttat tttcaatata tggtttatta tgcttatctc taaaagaaac
      781 tatattttca attggaacac ctaatatcat ttcaaagact ttgtttaaaa gacttcttga
      841 aactgcaaaa tttattttcg caacttccga cttatatgca tcaagttttt caatttcttc
      901 ttctttcaaa aaatttttca aatcttttat cataaattca cttgtgttag atgtaactaa
      961 caccatatca aaaaaaatta gtaacctact tatatcaatt aaacttcgta gttctttttt
     1021 atctgaaatt tctattctat atattttcat tggaataaac aaattcttca attgctttta
     1081 tcacactttc aggagatgta tttacaaaca tatgcttgcc attaatatat ctgtaagaga
     1141 attctttcgt cgtataatct tgccatttta aaagttcttc aagttccatt tcttcatcaa
     1201 tatcacccat cagacctaaa atcttgctat tcaatttttc cccttttgta tcctggtagt
     1261 cctcatcgat aataaaatcg gctcttagtg ttggtaaaaa aatcccaatc aaatctttat
     1321 tgtctaatat ctcatttgga gtaccatcat atcttcttaa cccttcaata aatccttcat
     1381 catctaaatg ataaatcgga ttcggttcct tatagcaagg ggctcgccca gctgatatga
     1441 taattccatt cggatttggt aacccatttt ctttaatttt cagagccaat tcataagcaa
     1501 tcttagttcc catactatgc ccgaaaaaat aataaggtga gttaaaatca aaagtcattt
     1561 ttaagtcttc aaacaatcct tttacaagtt cttctatgtt gctaattgct ttttcagaaa
     1621 acctgttttc tctccctgga tactgtgcaa cgaagagatt tatatcttta aattgattac
     1681 cccatcttct gaatgatgat actccaccac ctgcaaatgg aaacacaaat aaactagctt
     1741 tcgtgttttc catttcttta ttaacgtatt cgaaccacat tcccatcaaa acaccttcca
     1801 tctgattatt aatatactac tagaactatt attgttagat acatctaaca ataatagttt
     1861 aatccttcta acataaaaag tcaatacatt tacactgttt tatagttata tt
//
LOCUS       DARYNN010000113         1698 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.114, whole genome shotgun sequence.
ACCESSION   DARYNN010000113 DARYNN010000000
VERSION     DARYNN010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1698)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1698)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1698
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.114"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(182..724)
                     /locus_tag="TVB59_002015"
     CDS             complement(182..724)
                     /locus_tag="TVB59_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PH domain-containing protein"
                     /protein_id="HEL1010850.1"
                     /translation="MNLDTVLQQMKECGAYDTWGTKKEVKALPEILSDDEIIQYATSG
                     FVNGNTVLVVLTQKRILFIDKGMLYGIRSTEIPLDMVNSVSYSKGLILGAIAVMNGAT
                     KIEISNIAKDTCPVLTEKIKDCVEQYKYNLYQHQSPQKTATVGSEDAVAEIRKFKKLY
                     DEGILTEEEFIAKKKIILGI"
     gene            complement(750..1535)
                     /locus_tag="TVB59_002016"
     CDS             complement(750..1535)
                     /locus_tag="TVB59_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1010851.1"
                     /translation="MNDKELALYIGSKIKELRKNKGLTQKELAILVNMGDTTIANYEK
                     GFRTPKKNTLFKLANALSVTIDELFPPINKKNKENIVHLKQQSNTTEINNKVALLDKE
                     LKEPRHSYWVKYGENLLSEQNTVGHSKNTVEEPQAAYYTYNYYDHAASAGTGQYLSDV
                     QVETIELPVDYDADFVIPVYGDSMEPEYHSGDYVFVKLSVELTDGDIGVFEYYGDAYI
                     KQLLINDEGAFLHSLNSKYEDIPVDRDSDFRIIGEVVGSYSEK"
BASE COUNT          493 a          316 c          274 g          615 t
ORIGIN      
        1 gacttttgga cgaggtcgtt tgaaaggata ttggcatcac cacctttgtg tgatataatt
       61 ttaggtacaa gaaaacgacc tttttaatgg ttgtttctta tacggtttcg cctcacgctc
      121 agactcgcca aagtttgaga gcgtggggct ttttttattt tttaacggtt aactttacac
      181 cttaaattcc taaaattatt tttttcttag ctataaactc ttcctctgta agaatgcctt
      241 catcataaag ttttttaaac ttacggattt cagcaacggc atcttccgag cctacagttg
      301 ctgttttctg aggcgattga tgttggtaca gattatattt gtattgttct acacaatctt
      361 ttattttttc ggtaagtaca gggcaagtgt ccttggcaat attagatatt tcaatttttg
      421 tggctccgtt cataacagct attgcgccaa gaattaaacc tttagagtat gagacgctat
      481 taaccatatc aagaggaatt tctgtcgatc taattccata taacattccc ttatcgataa
      541 ataaaattcg tttttgggtc aatacaacaa ggacagtatt gccgtttaca aacccagatg
      601 ttgcgtattg gataatttcg tcatctgaca aaatttctgg caaagccttt acttctttct
      661 ttgtccccca agtgtcgtaa gccccacatt ccttcatttg ttgcaaaaca gtatctaaat
      721 tcataataaa actccttata aaaatattct tatttttcag aataactccc cacaacttca
      781 ccaataattc taaagtcgct atctctatct acgggtatat cttcatactt gctatttaaa
      841 ctgtgcagaa atgccccctc gtcatttata agtagctgtt tgatataagc gtcaccataa
      901 tactcaaaaa cgcctatatc gccatctgtt agctctacgg atagcttaac aaagacatag
      961 tccccagagt gatattcggg ttccatggaa tctccataaa caggaataac aaaatcagcg
     1021 tcataatcaa ctggtaattc aattgtttct acttgcacat cacttaaata ttgaccagta
     1081 ccagcagaag cagcgtggtc gtagtagttg taggtgtagt aggcggcttg tggttcttct
     1141 actgtattct tactgtgtcc tactgtgttt tgttcagata aaagattttc accgtatttt
     1201 acccaataac tatgacgagg ttctttgagc tctttgtcta ataaagcgac tttgttatta
     1261 atttctgtgg tgttagattg ctgtttaaga tgtacgatat tttctttatt ttttttattt
     1321 ataggaggga agagttcatc tatagtaaca gatagggcat tcgcaagttt aaacaaagta
     1381 ttttttttag gcgttctaaa ccccttttca tagttagcaa ttgtagtatc ccccatatta
     1441 accaagattg ctaactcttt ttgagttagc cctttatttt ttctcagttc cttgatttta
     1501 gagccgatat ataaagctag ctctttatca ttcatttgaa ttcttctttc tttttattta
     1561 ataatagtat aacacataaa ttcacgtttt gaaaagtttt tttgtttttt cgaaaaaaaa
     1621 cagttgacac ttcacgaaaa gtgaagtaca atataatcaa gcttaaggaa ttaagcaaaa
     1681 taaaaactcc caagaggg
//
LOCUS       DARYNN010000114         1608 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.115, whole genome shotgun sequence.
ACCESSION   DARYNN010000114 DARYNN010000000
VERSION     DARYNN010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1608)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1608)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1608
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.115"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            91..648
                     /gene="efp"
                     /locus_tag="TVB59_002017"
     CDS             91..648
                     /gene="efp"
                     /locus_tag="TVB59_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEL1010852.1"
                     /translation="MIEASKLRAGMTFEAEGKLIRVLEASHHKPGKGNTIMRMKLRDV
                     RTGSTFDTTYRPDEKFEQAIIETVPAQYLYKMDETAYFMNTETYDQYEIPVANVEQEL
                     LYILENSDVKIQFYGTEVIGVQVPTTVELTVTETQPSIKGATVTGSGKPATLETGLVV
                     NVPDFIEVGQKLIINTAEGTYVSRA"
     gene            691..1080
                     /locus_tag="TVB59_002018"
     CDS             691..1080
                     /locus_tag="TVB59_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEL1010853.1"
                     /translation="MTTENIGEIVISPRVLEVITGIATMQVEGVHSLHNKNMADTFNK
                     ASLGKGVYLQTEENGTVNADIYVYLQYGVKVPAVSMAIQRAVKSAVYDMAEVTISYVN
                     IHVEGIVPEKTPKPEMKSLFDEDFLDD"
     gene            1073..1525
                     /gene="nusB"
                     /locus_tag="TVB59_002019"
     CDS             1073..1525
                     /gene="nusB"
                     /locus_tag="TVB59_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEL1010854.1"
                     /translation="MTKHFQHSRRDLRERAFQALFAMEMGGDFLPASQFAYDYDKEAA
                     DDKQPSELPVFLLNLVNGVMDHKAELDEVIKKNLKTSWSIERLTVVDKTMLRLGLFEM
                     TLFEETPDRVALNEIIEIAKKYSDDTSAKFINGLLSQFVSDESAAVTE"
BASE COUNT          483 a          289 c          375 g          461 t
ORIGIN      
        1 aagggctgat aatggtcata aaacatttga gcctacagct cttttgtggt aaaataagac
       61 gataactatt ttagtaagag gtaataacaa atgattgaag caagcaagct tagagcaggt
      121 atgacgtttg aagcagaagg aaagctaatt cgcgtacttg aagcaagcca tcataagcca
      181 ggtaagggaa acactatcat gcgtatgaaa ttgcgtgatg ttcgtactgg ctctacattc
      241 gacacaacct atcgtccaga cgaaaagttt gaacaggcta ttatcgaaac agtgccggct
      301 caataccttt acaagatgga cgagactgct tactttatga atactgaaac ctatgaccag
      361 tatgagattc cagtagccaa tgttgagcaa gagctattat atatccttga aaactctgat
      421 gtgaaaatcc agttttatgg aacagaggtg atcggagttc aggtaccgac tactgttgag
      481 ttgactgtta cagagaccca gccatcaatc aagggagcaa ctgttacagg ctctggtaag
      541 cctgcaaccc ttgaaacagg actcgtggta aacgttccag actttattga ggtaggacaa
      601 aagctaatca tcaatactgc tgaggggact tacgtttctc gcgcttaatt cgctttccgg
      661 aattagtcta agagaaagaa aggaaatgct atgacaactg aaaatatcgg tgaaattgtt
      721 atttcgccac gagttcttga ggttattacg ggaattgcta cgatgcaggt cgagggtgtt
      781 cactcgcttc acaataaaaa catggcagat acctttaata aagctagtct tggtaagggc
      841 gtctatcttc agacggaaga aaatggaaca gtcaatgcag acatctatgt ttacctgcaa
      901 tatggtgtaa aggttcctgc ggtgtcaatg gctattcaaa gggctgttaa gtcagctgtt
      961 tatgacatgg ctgaggttac catttcttat gttaatatcc atgttgaggg gattgttcct
     1021 gaaaagacac caaagccaga aatgaaatca ttgtttgatg aggatttttt ggatgactaa
     1081 gcattttcaa cattcgagaa gagatttgcg tgagcgtgct tttcaagctt tatttgctat
     1141 ggagatgggc ggagattttc tgcctgcctc acagtttgcc tatgactatg acaaggaagc
     1201 agctgatgac aagcagcctt ctgagcttcc tgtttttctg ttaaatcttg tcaatggcgt
     1261 tatggatcat aaggctgagc ttgatgaggt tatcaagaaa aaccttaaaa cgagctggtc
     1321 cattgagcgc ttgacagtgg tagacaagac gatgttgcgt cttgggctct ttgagatgac
     1381 cctgtttgag gagacacctg atcgtgtagc cttaaatgaa atcattgaaa ttgctaaaaa
     1441 atattctgat gatacctcag ctaagtttat taatggctta ctcagtcagt ttgtttctga
     1501 tgagtcagct gcagtgacag aataacaagc tggtgaaagc ttcttaagtt actaaagccc
     1561 tatagggctt tttgaatgct caaaaacgtc tcatctggtt ggctatgt
//
LOCUS       DARYNN010000115         1518 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.116, whole genome shotgun sequence.
ACCESSION   DARYNN010000115 DARYNN010000000
VERSION     DARYNN010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1518)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1518)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1518
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.116"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            <1..201
                     /locus_tag="TVB59_002020"
     CDS             <1..201
                     /locus_tag="TVB59_002020"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010855.1"
                     /translation="ISPYIGNVEVILNDKYMCDYGISDENVLKQWKDICFGIFTSHKV
                     KKELIKEFLLKTTMTEENNNEQ"
     gene            191..778
                     /locus_tag="TVB59_002021"
     CDS             191..778
                     /locus_tag="TVB59_002021"
                     /inference="COORDINATES: protein motif:HMM:TIGR02185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEL1010856.1"
                     /translation="MSNKLKGKDLITIGIYTAIYFVINFAFMLAGMIPVMWIMMPSLI
                     ALFTGVPYMMICNKVQKAGAILIMGTVTVLIYYATGQFTTVILATFAVGCILAEIIRA
                     ITRYTSFIGNTLSFALFSIGMIGSPLPIWLFKESFFAHISEVGMSQDYINALEKFTSP
                     AILIGVIILTFICSLVGALIAKRMMNKHFKKAGII"
     gene            780..1451
                     /locus_tag="TVB59_002022"
     CDS             780..1451
                     /locus_tag="TVB59_002022"
                     /inference="COORDINATES: protein motif:HMM:NF014420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEL1010857.1"
                     /translation="MREYRLKIDPRAGISLLFILNFTIFNVSTVYALFVLLIWNCVYA
                     MCNGYCRIAIKFIFTYWLLYLIEFLVLPKLPSLIAISFAILLTYILKMLPVALFGYVF
                     VKTTSLYELITALRKIHFPESIITGLSITLRYFPALREDFHKTYDAMKLKNMSVLEKI
                     SGLIITTMTRATLNIEELSQAASVRGIDNPVKKFSAAEINFKTSDAVVFIVSSVVYIF
                     ICVRY"
BASE COUNT          529 a          168 c          267 g          554 t
ORIGIN      
        1 atatctccat atattggaaa tgtagaggtt attttaaatg ataaatatat gtgtgattac
       61 ggaatttctg atgaaaatgt attaaaacaa tggaaagata tatgctttgg catttttaca
      121 agtcataaag taaaaaaaga attaattaaa gaatttttat taaaaactac gatgacagag
      181 gagaataata atgagcaata agttaaaagg aaaagattta ataacaatag gcatttatac
      241 agcaatttat tttgtaataa attttgcatt tatgctagct ggaatgatac cagttatgtg
      301 gattatgatg ccttcactga tagctttatt tacaggggtg ccatacatga tgatttgcaa
      361 caaagttcaa aaagctggtg ctattttaat catgggaaca gttacagttt tgatatatta
      421 tgcaacagga caatttacaa cagttattct tgcaactttt gcagtaggtt gtatattagc
      481 tgaaattatt agagcaatta ctagatatac aagttttata gggaatactt tatcatttgc
      541 actattttca attggaatga taggatcgcc tcttcctatt tggttgttta aagaatcatt
      601 ttttgctcat atatcagagg ttggtatgtc gcaggattac ataaatgcct tggaaaagtt
      661 tacttcgcca gcgattttga taggagttat tattttgact tttatttgtt cgttagttgg
      721 ggctttgatt gcgaaaagaa tgatgaataa acattttaaa aaagcgggaa ttatataaaa
      781 tgcgtgaata tagattaaaa atagatccga gagcagggat ttccctgctt tttatcttaa
      841 actttacgat atttaatgta tccacagttt atgcattatt tgtgctatta atttggaact
      901 gtgtttatgc aatgtgtaat ggatattgta ggatagcaat caaattcatt tttacttatt
      961 ggttgcttta tttgatagaa tttttggttt taccgaaact accaagttta attgctattt
     1021 cctttgctat tctattaact tatattttaa agatgttacc agtagcattg tttggatatg
     1081 tttttgttaa aactacaagt ttgtatgagt taattacggc acttagaaaa attcattttc
     1141 cagaaagtat aataacggga ttatcaataa ctcttagata ttttccggca ttaagagaag
     1201 attttcataa aacatatgat gctatgaaac taaaaaatat gtctgtttta gaaaaaataa
     1261 gtggactgat aattactaca atgacaagag ccacattaaa tatagaagaa ttatctcagg
     1321 cagcaagtgt aagaggcata gataatcctg taaaaaaatt ttctgcggct gaaataaatt
     1381 ttaagacaag tgatgcggta gtgtttatag tgtcttctgt tgtctatatt tttatatgtg
     1441 ttaggtattg actggaggat agatatggtt gaattaaaaa atatttcata ttcatattca
     1501 aaagaaaatc aaatatta
//
LOCUS       DARYNN010000116         1503 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.117, whole genome shotgun sequence.
ACCESSION   DARYNN010000116 DARYNN010000000
VERSION     DARYNN010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1503)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1503)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1503
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.117"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            71..1468
                     /locus_tag="TVB59_002023"
     CDS             71..1468
                     /locus_tag="TVB59_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISNCY family transposase"
                     /protein_id="HEL1010858.1"
                     /translation="MIESKKYLVIKAVCEGKKQKNRACVELGLSKRQVNRLILAYREK
                     GKSAFVHGNRSKRPTHAMSLETKRRIIEKYQSYGDLRPNVVHFCELLAEEENIAYSDT
                     TVRKLLYQAGFLSPKTQRATKRRLKQEAKQKKREAEKRGSKLPTASNFFEEPDKAHPS
                     RARKKFKGELIQMEASQFPWFGQQETHLHVAIDDASGDIVGAYFDTQETLNGYYHVLE
                     QILEVHGIPFQFLTDKRTVFTYASSQSKKIEEDTFTQFGYACHQLGIAIETSSIPQAK
                     GRVERLNQTLQSRLPIDLQRNQITSISQANRYLKRWIKRFNKQFGGLASESVFEKAPK
                     PAQRNLLLARISERVIDSGHHIRYQNNFYLPVEGDKKIYFTRKTKALVIEAFDGDIYL
                     NIADNIYATRKLPKHEKHSKEFEMVPKTKKERRKYIPPQSHPWKLASFKQYLHKIGKS
                     YEEFKRERNTSQPQL"
BASE COUNT          530 a          300 c          299 g          374 t
ORIGIN      
        1 gtcttagcta ggtcgaatgt gaaaatgtcc cgtctgttaa actagaaaga tgaggaaaat
       61 agaactaact atgatagagt caaagaaata cctagtcatc aaagctgttt gtgagggtaa
      121 aaaacagaaa aacagggctt gtgtagaatt agggttaagc aagaggcagg tgaaccgatt
      181 gatactagcc tatcgagaga aaggaaagtc agctttcgtt catggtaata gatcaaaaag
      241 accaactcat gccatgtctt tagaaacaaa gagaaggatt atcgagaaat atcaaagtta
      301 cggtgattta agaccaaatg ttgttcattt ctgcgaacta ctagcggaag aagaaaacat
      361 cgcctattca gatacaactg ttagaaaact actctaccaa gcagggtttc tatctccaaa
      421 gactcaacga gcaacgaaaa gacgattgaa acaagaagcc aaacaaaaga aaagggaggc
      481 agaaaaaaga ggatccaaac tcccaactgc ttccaacttc tttgaagaac ctgacaaagc
      541 tcatcccagc cgagcaagaa agaaattcaa aggggaactc attcaaatgg aggccagtca
      601 attcccttgg tttggacaac aggaaacaca tcttcatgtc gctattgacg atgcctccgg
      661 tgatattgtc ggggcttact ttgatactca ggagacgcta aacgggtatt atcatgtctt
      721 agaacagatt ctagaggtac atggtatccc tttccagttc cttactgata aaaggactgt
      781 attcacttat gcttccagtc agtctaaaaa gatcgaggaa gataccttta cacagtttgg
      841 atatgcttgc catcagcttg gtattgccat tgaaacgtct tctatccctc aagctaaagg
      901 gcgtgtagaa cgtcttaatc agacccttca atcgcgtcta ccaattgatt tacagaggaa
      961 tcaaattacc agcatctctc aagcgaatcg ttatcttaag agatggatta aacgatttaa
     1021 caagcagttt ggtggactgg ccagtgagtc tgtttttgag aaagcaccta aaccggccca
     1081 gcgaaaccta ctgttagcga gaatctctga aagagtaatt gatagtgggc atcatattcg
     1141 atatcaaaac aacttctact tgcccgtcga aggggataaa aaaatctatt ttacgcgtaa
     1201 gacaaaggca cttgtgattg aggcattcga tggagacatc taccttaata tcgcagacaa
     1261 tatttatgcc actagaaagt taccaaaaca cgagaagcac tccaaagaat tcgaaatggt
     1321 gcctaaaact aaaaaagaaa gacgcaagta tattccacca caatcccatc cgtggaaact
     1381 tgcatctttc aaacaatacc ttcataaaat cggaaaatct tatgaagaat tcaagcgtga
     1441 gaggaatacc tctcaaccac aattataaca gatttttctc ttatctaacc gattttttca
     1501 aga
//
LOCUS       DARYNN010000117         1408 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.118, whole genome shotgun sequence.
ACCESSION   DARYNN010000117 DARYNN010000000
VERSION     DARYNN010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1408)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1408)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1408
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.118"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            <1..782
                     /locus_tag="TVB59_002024"
     CDS             <1..782
                     /locus_tag="TVB59_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1010859.1"
                     /translation="DFLDDNGKDMELSSHNIVFDKVRFAYDKIPIIKDVSFEIKENTV
                     TAIIGPSGSGKTTICNLISRFYDVSGGSIKIGNVNIKNLTLSSLLSNISTVFQKVYLF
                     NDTIENNIKFGNPNVSKEEIINAAKKSHCHEFIMNLPNGYETIVGEGGDFLSGGEKQR
                     ISIARAMLKDAPIIILDEATSSIDPENEYLIQRAISNLSKGKTVIIIAHRIVTIEEAD
                     QIIVLKEGEIAQIGKHTELMSQDGLYRDYMRIRGKTEDWKI"
     gene            802..>1408
                     /locus_tag="TVB59_002025"
     CDS             802..>1408
                     /locus_tag="TVB59_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase NADP-binding
                     domain-containing protein"
                     /protein_id="HEL1010860.1"
                     /translation="MYNIGVLGCNGNIGSLFMEKVSKWEDNYIYAVSRSHMNFIKKDN
                     IEYIFFDAENIEKLDKFCSKCDVIVNCTGIDKTNIMNICLKNDVNYVDPSFVDTDIMS
                     KKLMETNDNCIICSAGCNPGLTEVLAKYISIKFNPKICEIIFSGNGSMSKSAINELLD
                     LSGEYRSNFRSFIKFKSIEKLEYWDLKRKLNDSYGDVICMPV"
BASE COUNT          549 a          133 c          274 g          452 t
ORIGIN      
        1 ctgatttttt ggatgacaat ggaaaagaca tggaattgag tagtcataat attgtttttg
       61 acaaagtaag atttgcatat gataaaatcc caattataaa ggatgtttca tttgagataa
      121 aggaaaatac ggtaacagct attataggac catcagggtc aggtaaaaca acaatttgta
      181 atctcatttc tcgtttttat gatgtaagtg gtgggagtat aaaaattgga aatgtaaata
      241 taaaaaattt gactttatca agtttacttt caaatataag tacagtattt caaaaggtgt
      301 atttgtttaa tgatacaatc gaaaacaata taaaatttgg taatccgaat gtaagtaagg
      361 aagaaataat aaatgcagcg aagaagtcac attgtcatga atttataatg aatttgccaa
      421 atggatatga aactattgtt ggtgaaggtg gtgatttttt atctggtgga gaaaaacaaa
      481 gaatatctat agcaagggca atgctaaaag atgctccaat tattattttg gatgaagcaa
      541 catcaagcat agatcctgaa aacgaatatt taattcaaag agcaatatcg aatttgagta
      601 aaggtaagac tgtaattatt attgctcata gaattgtaac aattgaagaa gcagatcaga
      661 taattgtttt gaaagaagga gagattgctc aaataggaaa gcatacagaa ctgatgagcc
      721 aagatggtct gtatagagat tatatgagaa tcaggggtaa aacagaggac tggaaaatat
      781 aatatagata ggaggaggtt tatgtataat ataggagttt taggttgcaa tggtaatata
      841 ggttcgcttt ttatggaaaa agtgtctaaa tgggaagata attatattta tgctgtatcg
      901 agaagtcata tgaattttat taagaaagat aacatagaat acatattttt tgatgcagag
      961 aacatagaaa aattagacaa attctgttct aaatgcgatg tgattgtaaa ttgtactgga
     1021 atagataaaa ctaatattat gaatatatgt ttaaaaaatg atgttaatta cgtagatcca
     1081 tcttttgttg acacagatat tatgtctaaa aaacttatgg aaacaaatga taactgtata
     1141 atttgttcgg caggttgcaa tccgggctta acagaagttt tagctaaata tattagcatc
     1201 aaatttaatc ctaaaatatg tgaaatcata ttttctggaa atggaagtat gtcgaaatct
     1261 gctataaacg aattattgga tttatctgga gaatacagaa gtaattttcg ttcttttatc
     1321 aaatttaaga gtatagaaaa attggaatac tgggatttga aaagaaaatt aaatgattca
     1381 tatggagacg ttatttgtat gccagtta
//
LOCUS       DARYNN010000118         1335 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.119, whole genome shotgun sequence.
ACCESSION   DARYNN010000118 DARYNN010000000
VERSION     DARYNN010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1335)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1335)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1335
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.119"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            <1..724
                     /locus_tag="TVB59_002026"
     CDS             <1..724
                     /locus_tag="TVB59_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1010861.1"
                     /translation="IKRTFSGDEFFRLENKERISMGLRTLEVPKLKNMLTYDEICDNT
                     LKIKNLSCCYGEKIVFKNLNLSIRSGEILGIIGNNGVGKTTLLRCIAGLHKETKGEIT
                     LNGDVISGKKRQRLSAMVMQDVNYQLFADSLVEECCLGNNCDNIQIDKVLGELKLIES
                     KKSHPMILSGGQKQRLVVANAILSDKKILIFDEPTSGLDYEGMLAVSNELKKLSEKNY
                     YIFVVSHDIEFINEICDRVYEF"
     gene            747..>1335
                     /locus_tag="TVB59_002027"
     CDS             747..>1335
                     /locus_tag="TVB59_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1010862.1"
                     /translation="MSNKNWINTILDFASDCKGKLILSVVMASIGVFFSIIPYWSVYK
                     LMAVFIEQKATGEDVLYYGAIGIIAYFIRYICHGVSTILSHISAYTILRNIRENLGEK
                     LLSISMGNASKKTIGEYKSIIVDKVETIEMPLAHIIPECVAALLLSLGIAIFMVFISW
                     EMALAMFITVPFALMAYKKLMGNFNQLYEAQMKSNK"
BASE COUNT          500 a          137 c          262 g          436 t
ORIGIN      
        1 aattaaaaga actttttcag gggatgagtt ttttagatta gaaaataaag aaagaatatc
       61 tatgggtctt agaactttag aggtaccgaa gttaaaaaat atgcttactt atgatgaaat
      121 atgtgataat acgttaaaaa ttaagaattt gtcttgttgt tatggagaaa aaatagtttt
      181 taaaaattta aatctaagca taagatctgg agaaatatta ggaattatag gaaataacgg
      241 tgttggaaag actacacttc ttcgatgtat tgcaggatta cataaagaaa caaaaggaga
      301 aattacatta aatggtgatg ttataagtgg caaaaaaaga caaaggctat ctgcaatggt
      361 tatgcaagat gtgaattatc agttatttgc agatagctta gtagaagaat gttgcttagg
      421 aaataactgt gataatatac aaattgataa ggttttgggt gaactaaaat taattgagtc
      481 aaaaaaatca catcctatga tactttccgg tggacaaaaa caaaggttag tagttgcaaa
      541 tgcgatttta tctgataaga aaatattaat ttttgatgaa ccgacatcag gattggatta
      601 tgaaggtatg cttgcagtgt ctaatgaact aaagaagttg agtgaaaaaa attactatat
      661 ttttgtggtt tcacacgata tagaatttat aaatgaaata tgtgatagag tttatgaatt
      721 ttagataaag gaggtggaga agttacatga gcaacaaaaa ctggataaat actatattag
      781 attttgcttc agattgtaaa ggaaagttga ttttatcagt agttatggct agtataggag
      841 tgttctttag cattatacct tattggtcag tatataaact tatggcagtc tttatagaac
      901 aaaaagcaac tggagaagat gtattgtatt atggagcgat tggtattatt gcatatttta
      961 tcagatatat ttgccatgga gtatcaacaa tattatctca tatatccgct tacacaatct
     1021 taagaaatat aagagaaaat ttaggtgaaa aattgctcag tatttctatg ggaaatgcgt
     1081 caaaaaagac aataggagaa tataagtcaa ttattgtaga caaagttgaa acaattgaga
     1141 tgcctctagc acatatcata ccagagtgtg ttgctgcatt gcttttatca ctaggtattg
     1201 caatatttat ggtcttcata agttgggaga tggctcttgc gatgtttatt acagtgcctt
     1261 ttgctttgat ggcatataaa aaactaatgg gtaattttaa tcagctttat gaagctcaaa
     1321 tgaaatctaa caagt
//
LOCUS       DARYNN010000119         1310 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.120, whole genome shotgun sequence.
ACCESSION   DARYNN010000119 DARYNN010000000
VERSION     DARYNN010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1310)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1310)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1310
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.120"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(146..538)
                     /locus_tag="TVB59_002028"
                     /pseudo
     CDS             complement(146..538)
                     /locus_tag="TVB59_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
     gene            complement(535..1062)
                     /locus_tag="TVB59_002029"
     CDS             complement(535..1062)
                     /locus_tag="TVB59_002029"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEL1010863.1"
                     /translation="MIKKDYRQLVLQRLAMMTPEDKLEKDLALLAAVVASSSYQEAQT
                     LVTYLPLPHEYQSHLLIERALQDGKTILVPKTRSRGEMVFVAYDPCDLIQTAFGLMEP
                     RCTIAVAKSEIDAIHVPGLVFHPAGYRIGYGGGYYDRYLRDYQGATFSTIYACQWEDF
                     VVEAHDIAVKEVYCQ"
BASE COUNT          421 a          330 c          251 g          308 t
ORIGIN      
        1 ggtaaagcac tagaaagcac tcaacagcag acaaaatagg agttggggca accgtcctag
       61 aagcattaaa aagcaacagc agcaaaaccg ttgctttttg tttaaatcaa agatacacct
      121 gtcctagcac ttataagctt gaaggaaaaa gaccaaaaag agaggtggaa gcacctgctg
      181 ctacggtatc tggtgtcagc cacatgataa aagcattccc cataatccct gaacacacat
      241 acagcagcaa aaactgtctt gacccccaaa tggtctcagc catccgcccg acaaaataaa
      301 gggttaaggt attaatgaaa aaatgctcaa agccaatatg aaccactata ggtgtcacca
      361 agcgccaaag ctgatcaggc attgctctga caacaagacc attcatgcca ccaaatataa
      421 caacagcata agggtgcgta gcaaactggc catagaccag ctgcattatc aaaaaaacta
      481 aaccagtcaa gcccaagaaa aagagtgtta tcgggtattt tttgatcatc agtctcattg
      541 gcaatacacc tccttcacag caatatcatg tgcctctacc acaaaatcct cccactgaca
      601 ggcataaatc gtgctaaagg tagccccctg ataatccctc aaataacgat catagtagcc
      661 accaccatag cctatacgat agcctgcagg gtgaaaaaca agccctggca catgaatggc
      721 atcaatctcc gacttagcaa cagctatggt acacctaggc tccataagac caaaagccgt
      781 ctgtatcaag tcacaaggat cataagccac aaacaccatc tctccacgag aacgagtctt
      841 gggcacaagg atagtcttgc cgtcctgcaa ggctcgctca atcagtagat ggctttgata
      901 ctcgtgtggc aagggcagat aggtcacaag agtctgcgcc tcttgatagc tgctactagc
      961 aactactgct gccaatagag ctaagtcctt ttccagctta tcctctgggg tcatcatggc
     1021 taggcgctga agcactagtt ggcgataatc ttttttaatc atgcccatat cataacacaa
     1081 agcgctgcta ctattcaaga atcggccaca atcaaggttc tttccttagt tgtcctacca
     1141 gacagggcag cagctcaatc agtgaatgtc cttcttactt cttgaggtga gcttgtggtc
     1201 tcatgagatc aaaaaattat ttttctaggt taagaaaagt ttaagcttta tgctatacac
     1261 ccgactttat cacttgtttt agtccacacc ttactcaacc ccttggtaga
//
LOCUS       DARYNN010000120         1284 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.121, whole genome shotgun sequence.
ACCESSION   DARYNN010000120 DARYNN010000000
VERSION     DARYNN010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1284)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1284)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1284
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.121"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            83..1284
                     /locus_tag="TVB59_002030"
                     /pseudo
     CDS             83..1284
                     /locus_tag="TVB59_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISSeq1 family transposase"
BASE COUNT          392 a          309 c          240 g          343 t
ORIGIN      
        1 gttatagggc tttatgagta tcaaaaaagt cccatatgac ctataatgaa aagcgactaa
       61 actatcattt agaaagactc atatggaaca atcacatgtt atcacacaac tactgggaat
      121 taaagaccct catatcacat tctccaaaga aatacacgac atgaaaactc ataaggaatt
      181 gaaagctgtc cttgactacg atgccccacc ttgccctaac tgccaaagtc agatgggcaa
      241 gtacgacttc caacgggaat ccaaggtccc ttttctcgat tgcgcaggct acaagacttt
      301 gattcgcctc aaaaagcgcc gtttcaaatg tcagttttgc ggaaaaatta ctgtcgctga
      361 gacttctcta gtccctaaaa accatcaaat accaaccatc gtcaaacaga aggtggccca
      421 gcttctcatc gagaaagtct ccatgaccgc tatcgctgat agactatcca tctccacctc
      481 aaccgtcatg cgaaagctca acgagttcac gttcaagtct catttgactt atttacccga
      541 acatatgtcc tgggatgaat atgcctttaa gaagggcaag atgagcttta ttgctcagga
      601 ctttgacacc aacaacatca tcgctatttt ggatggacgg acgaaagctg tcattcgcaa
      661 ccacttcctg agatatcctc ggcaggtcag aaacgacgtt aaactcatca ccatggatat
      721 gtttaccccc tattacaacc tggctaagat gcttttccca aacgcttaga ttgtccttga
      781 tcgtttccac attgtgcaac atttgggacg tgccatgaac cgtatccgta ctcaaatcat
      841 gaactctttt gatcgaaaat cccacgaata caaggctttg aaacgttact ggaagctgat
      901 tcaacaagat agtagcaaac ttagtgacaa gcgtttttac cgcccgactt ttcgcatgca
      961 tttgacaaac aaggaggtgg tcgagcgtct tttgagctac tctgacgagc ttagaaagca
     1021 ttatgacctt tatcagcttc tgctttttca cttccaggaa aagcaagctg accacttttt
     1081 cggcctgatt gaggagcaga tagacagtag caatcctctc tttcagaccg ttttcaagac
     1141 ctttttgaaa gacagagaca agattgagaa cgcactggat ttgccttatt ctaacgctaa
     1201 actggaggct accaataatc tcatcaaagt catcaagcgc aatgcttttg gatttcggaa
     1261 ctttgaaaac tttaaaagac ggat
//
LOCUS       DARYNN010000121         1237 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.122, whole genome shotgun sequence.
ACCESSION   DARYNN010000121 DARYNN010000000
VERSION     DARYNN010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1237)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1237)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1237
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.122"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            <1..318
                     /locus_tag="TVB59_002031"
     CDS             <1..318
                     /locus_tag="TVB59_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010864.1"
                     /translation="ARAAAERTQKMINLQTIHVLTSGGKIEPDIYKGMLELIEPAKKG
                     QYQEHDVFTVLDDKHEDLAGEGKLVFVYVNEAFEYDKQTLKDLESEDKVTVIKYADLV
                     KGK"
     gene            331..621
                     /locus_tag="TVB59_002032"
     CDS             331..621
                     /locus_tag="TVB59_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010865.1"
                     /translation="MIDFVQIGTFCGAALSIFGVWGFIVNPFKKALEANELAMAQLKD
                     SIKELAYELKNLDRDGEITKKIIDRHEERLGRVEDDIIVNKEQIKTLFKKGD"
     gene            624..803
                     /locus_tag="TVB59_002033"
     CDS             624..803
                     /locus_tag="TVB59_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010866.1"
                     /translation="MDKWFKKVAIKTIKTMAQTAVGVIGSSALITDVNWQVVASTVIM
                     SGIVCVLMNVSDIKE"
     gene            915..>1237
                     /locus_tag="TVB59_002034"
     CDS             915..>1237
                     /locus_tag="TVB59_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEL1010867.1"
                     /translation="MTFLDDIKSAVIAEWHNHKILPSLTAAQAILESGWGKYAPHNAL
                     FGIKADSSWSGKSFDTKTQEEYQPGVVTDLVDRFRAYDSWDESILDHGQFLVDNPRYK
                     SVIGET"
BASE COUNT          379 a          226 c          302 g          330 t
ORIGIN      
        1 gccagggcag ctgcagagcg cacacaaaag atgattaact tgcaaactat ccacgttttg
       61 acaagtggtg gcaagattga gcctgatatc tataaaggca tgcttgagct tattgagcca
      121 gctaaaaaag gtcagtatca agagcatgat gtctttactg tgctagatga caagcatgag
      181 gacttggccg gcgagggtaa acttgtcttt gtctatgtta acgaggcctt tgagtacgac
      241 aagcaaaccc tcaaagatct ggaatcagag gataaagtca cagttatcaa gtacgctgat
      301 ttggttaaag gcaaatagtg aggtgattag atgatagatt ttgtgcaaat aggcactttt
      361 tgtggcgctg ctctgtctat ctttggtgtt tggggattta tcgtcaatcc ttttaaaaaa
      421 gcgctggagg ctaacgagct agccatggcc caactcaaag actcgatcaa ggagctagcc
      481 tacgagctaa aaaatcttga tcgtgatgga gagataacca aaaagattat cgatcggcat
      541 gaggagcgtt taggacgtgt agaggacgac attattgtca ataaagagca aatcaaaaca
      601 ttatttaaaa aaggagacta aaaatggata aatggtttaa aaaagtagca atcaaaacaa
      661 ttaagacaat ggcccaaacc gctgtagggg ttattggatc aagcgcattg attactgacg
      721 tcaactggca ggtggtggcc tcaacagtta ttatgtcagg tattgtctgc gtcttgatga
      781 atgtgtctga catcaaggaa tagcattatg cgagcaatca cacgattagc aatagtccta
      841 gcaatcgcaa tactatattt accgctatct gtgattgctc ttatctttta tccgttttta
      901 ggtgaggagg acagatgacc tttttagacg acataaaaag cgcagttatc gcagagtggc
      961 acaatcataa gattttgcca tctctgacgg ctgctcaagc tattttagag agcggttggg
     1021 gcaagtatgc cccacataac gcattgtttg gtatcaaggc agatagctca tggtctggta
     1081 aatcttttga taccaagaca caagaggagt atcagccagg tgtcgtgacg gatctcgtgg
     1141 accgctttag agcctatgac agttgggacg agtcaatcct tgatcatggc cagtttttag
     1201 tggataatcc acgatacaaa tcagttatcg gggagac
//
LOCUS       DARYNN010000122         1188 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.123, whole genome shotgun sequence.
ACCESSION   DARYNN010000122 DARYNN010000000
VERSION     DARYNN010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1188)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1188)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1188
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.123"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(<1..>1188)
                     /locus_tag="TVB59_002035"
     CDS             complement(<1..>1188)
                     /locus_tag="TVB59_002035"
                     /inference="COORDINATES: protein motif:HMM:NF012873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010868.1"
                     /translation="YSLDIDELPLTEIQSAYLLGRRNHFELGGVASHVYMEVILPLLD
                     IDRAEKVWNDIILKHDALHSIFTSNNTQKVLKEFAYYKIECNEGADIKEKIALTRDKL
                     KGKSYNADIWPLFDISVSQLDDNSLLHLSFDFLILDWASIWILLKEFEECYFDGKTIM
                     DNSYDLKEIRTSQLKLKHSSKYLSDKDFWERRIPFLPDAPLLPIKNKIVKNGFERIQL
                     RIDENTWSKIKSNISEIGVTQTSFLVTILALVLNRWSSNSEFTINLTTMNRPKEYIKS
                     DVVNDFTSTELLEFRMESLQPFYVLLKHIQQQMIEDLQHETFTGVEVTREVRKNVERR
                     DAIFPFVFTSALGIKASEYKYISLQKEGLSETPQVLMDCQVMEVNHELIINFDLRADA
                     FSK"
BASE COUNT          384 a          217 c          137 g          450 t
ORIGIN      
        1 cttttgaaaa agcatctgct cttaagtcaa aattaattat tagttcatga tttacctcca
       61 ttacttgaca atccattaat acttgaggag tttcactcaa accttctttt tgtaaactaa
      121 tatatttata ttctgaagct tttattccta atgcacttgt gaaaacaaat ggaaatatag
      181 catctctcct ttctacattt ttcctaactt cacgagtaac ttccactcct gtaaatgttt
      241 catgttgcaa atcttcaatc atttgctgtt gtatgtgttt taataaaaca tagaatggtt
      301 gcagagattc cattctaaac tctaaaagtt ctgtagatgt aaaatcatta acaacatcgc
      361 tctttatata ctcctttggt ctattcatag ttgttaaatt aatggtaaat tcagaattag
      421 aactccatct attaagaaca agagctaata ttgtcaccaa gaaagatgtt tgcgtgacac
      481 caatctcact tatattagat tttatcttcg accaagtatt ttcatctatt ctaagttgta
      541 ttctttcaaa accatttttg actattttat ttttaattgg taatagtgga gcgtcaggca
      601 aaaaaggaat tcttctttcc cagaaatctt tatccgataa atacttagaa ctatgtttca
      661 gtttaagttg actcgttctt atttctttaa gatcataaga attatccata atcgtctttc
      721 cgtcaaaata acactcttca aattccttta ataaaatcca aatgcttgcc caatctaaaa
      781 tcaaaaaatc aaatgataaa tgcaataaac tattgtcatc taactgactt acacttatat
      841 cgaatagtgg ccatatatct gcattataac ttttcccctt aagtttatcc cttgttaatg
      901 caattttttc ttttatatct gcaccctcat tgcattcgat tttatagtaa gcaaattcct
      961 tcagtacttt ctgagtattg tttgatgtaa atattgaatg taatgcatcg tgctttagta
     1021 ttatatcatt ccaaaccttt tcagctcgat ctatatccaa tagaggtaat attacttcca
     1081 tataaacatg actggcaaca ccaccaagtt caaaatgatt tcttctacct aataaatatg
     1141 cactttgaat ttctgttaaa ggtaattcat caatatctag tgaatatc
//
LOCUS       DARYNN010000123         1112 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.124, whole genome shotgun sequence.
ACCESSION   DARYNN010000123 DARYNN010000000
VERSION     DARYNN010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1112)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1112)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1112
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.124"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            <1..211
                     /locus_tag="TVB59_002036"
     CDS             <1..211
                     /locus_tag="TVB59_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL1010869.1"
                     /translation="DVSPNLNVNWNMVTSKFYRGDLSRRISNNGSGLGLTIVNDIVKH
                     LGGNFEIGEENKRVCAKVILPYRLN"
     gene            489..872
                     /locus_tag="TVB59_002037"
     CDS             489..872
                     /locus_tag="TVB59_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEL1010870.1"
                     /translation="MKKALSLVLLTGLMLASSVPAFAAEETNLPYVEGLGYEVEVFEE
                     DYTQPKLFSYDSGWKSFLGGKWRHGVGSRYVWSKYDHNNKTHKTTVQGAGGQFSYSGW
                     TSAGSRAEASWEKALSGNRAWADVK"
BASE COUNT          404 a          116 c          241 g          351 t
ORIGIN      
        1 cgatgtttct ccaaatttaa atgtgaattg gaatatggtt acttcaaagt tttatagggg
       61 agatttatca agacgaataa gcaataatgg atcgggactt ggacttacaa ttgtaaatga
      121 cattgtaaaa cacttgggtg gaaattttga aattggagag gagaataaaa gagtttgtgc
      181 taaagtaata cttccatata gattaaatta aatcgcaaag aaaacgcaag aattattcaa
      241 agataccgtt aagtataaag caaagagcta ttctataatg tgagtaagga tagctctttt
      301 atatttgaaa ggaattatta atttgaataa gcatctgtga ttataaatat ataaaatgga
      361 ggtggagttt tatgaattac aataatcctc ataggtatag gaacggagat tgagtagagt
      421 tttgggaaac tttattcgga agaaaaattt tacaaaaaat ttaagtattt gagagaggag
      481 aatttatcat gaaaaaagca ttgtcattag tattattaac aggtttgatg ttagcatcat
      541 ctgtaccagc atttgcagca gaagaaacaa acttgccata tgttgaaggt cttggttatg
      601 aggtggaagt atttgaagaa gattatactc agccaaagtt gttcagttat gatagcggat
      661 ggaaaagttt tttaggtgga aaatggagac atggtgtagg tagtcgatat gtttggtcta
      721 aatacgatca caataataaa acacataaaa ctacagtaca aggtgctggt ggtcaattct
      781 cttattcggg ttggacaagc gctggaagta gagcagaagc ttcttgggaa aaagctttaa
      841 gtggtaatag ggcttgggct gatgttaaat aacaataaat aaaaaatagt tgaacgagtt
      901 tgagcggtgc cacgttgtta ttttagcatt gtggcattac tcatactcgc tatttttata
      961 aagttggaga tgatacagaa tgaaaaaaac agtgggtata ttggcaattt tactaattat
     1021 agtgattggt ataggaaagt ttttctattc agacggcatg tttttaaata tattcataaa
     1081 agagtttaat actactgtaa acattgtaac aa
//
LOCUS       DARYNN010000124         1077 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.125, whole genome shotgun sequence.
ACCESSION   DARYNN010000124 DARYNN010000000
VERSION     DARYNN010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1077)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1077)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1077
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.125"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            41..>1077
                     /locus_tag="TVB59_002038"
     CDS             41..>1077
                     /locus_tag="TVB59_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1634-like element ISSeq4 family transposase"
                     /protein_id="HEL1010871.1"
                     /translation="MAFIKTTTNKEGRTHVYLVEGYRKDGKVKQRILKKFGLLDELEL
                     EEPGILERLKREAKEDTLNNPKVLQVSYDLLAPMNQPDQSYGWMVLDNLFESLGLTAF
                     LKGIKTKSEYDLVQVLKLLVFQRILRPDSKLATYASQADLFGHWDISLNAIYRSLNKL
                     NTLKDDLQHHLHKVVSQMIKREASLVFYDVTNYYFETDIPDNELVSENGEILQEGLRR
                     RGPSKEHRPKPIVQLGLFRDTNGIPISYKLFRGNQTDPVTYLPAVEEVKKQFGIERLI
                     VVADKAMNSMANVSEMLKQEDGWLFSQKHRGRRGAPKDIQEHILDSSDWQFNPELTFA
                     KKSYIRERKLG"
BASE COUNT          337 a          209 c          228 g          303 t
ORIGIN      
        1 tttttcttgt tgtgtatggt tatatatgtt ataataaact atggctttta ttaaaacaac
       61 aacgaataaa gaaggtagga cgcatgtcta ccttgtagaa gggtatcgta aagatggtaa
      121 ggtcaaacag cgtatcctta aaaaatttgg tctcttagat gagcttgaat tggaagaacc
      181 agggattctt gagcgtctta agcgcgaagc taaagaagat actttaaata accctaaggt
      241 actccaggtt tcctatgacc tccttgcccc catgaaccaa ccggatcaat cttatggttg
      301 gatggttttg gataatctct tcgaatctct ggggctcaca gcctttttaa agggtatcaa
      361 aacgaagtct gagtatgact tagtgcaagt gctaaagcta ttagtttttc agagaattct
      421 ccgaccagat agtaaacttg ccacctatgc ctctcaagca gacttatttg gccattggga
      481 catcagctta aatgccattt atcgctcctt gaacaaattg aacaccttga aagatgatct
      541 tcaacatcat cttcacaagg tagtgagtca gatgatcaaa cgtgaagcca gtctcgtttt
      601 ctacgatgtc accaattatt attttgagac agatattcca gataacgagt tggtttcaga
      661 aaatggagag atactacaag aagggcttcg aagacgtggt ccgagtaagg aacaccgtcc
      721 aaaacccatt gtgcaattag gactctttag ggataccaac ggtattccga ttagctataa
      781 actgtttcga ggtaatcaaa ccgatcctgt tacctatctt ccagcggttg aggaagtcaa
      841 aaaacaattt ggaattgagc ggttaattgt agtcgccgat aaggcgatga atagtatggc
      901 taatgtttca gaaatgctca agcaagaaga tggctggctc ttctcacaga aacatcgcgg
      961 acgccgagga gctccaaaag atattcaaga acacatcctt gattcatcgg attggcaatt
     1021 taacccagaa cttaccttcg ctaagaaatc ttatatccgt gaacggaagt tagggaa
//
LOCUS       DARYNN010000125         1068 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.126, whole genome shotgun sequence.
ACCESSION   DARYNN010000125 DARYNN010000000
VERSION     DARYNN010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1068)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1068)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1068
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.126"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(<1..307)
                     /locus_tag="TVB59_002039"
     CDS             complement(<1..307)
                     /locus_tag="TVB59_002039"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010872.1"
                     /translation="MSNFWGAVQSDSDDIKYRIDSYNRYGIDGLAGKLYTNYIVGKIS
                     NDELNYGLQKIFAKLISTKMGRMVPIENNNGSPYVDSGNAGLITVLILLDPEKYKDII
                     "
     gene            364..1068
                     /locus_tag="TVB59_002040"
                     /pseudo
     CDS             364..1068
                     /locus_tag="TVB59_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560651.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
BASE COUNT          372 a          192 c          184 g          320 t
ORIGIN      
        1 tgataatatc tttatatttt tctggatcaa gtaatattaa aacagtaatt aaaccagcat
       61 ttcctgaatc tacgtaagga gatccattgt tattttcaat tggaaccatt ctacccattt
      121 tagtagaaat taatttagca aatatttttt gtaaaccata attaagttca tcatttgaaa
      181 tttttccaac aatatagtta gtataaagtt tacctgctaa accatcaatt ccatatctat
      241 tatatgaatc aatccgatat tttatatcat ctgaatcaga ctgaactgcc ccccaaaagt
      301 tagacataaa atctaacaat tggggggcta tttttatgtc taacttttgg ggggcagttc
      361 actattgacc ttatgtcggt cagaaacaat gaggactacc acaacgtcaa aataaaaaca
      421 gatttatcaa tttatggaag agcctacgag ctgttaactg ttgagaaaat agatgacaaa
      481 aaaaccgaag taaaactcta ccagctcccg gccgagcaaa cttttgttat ctatgatgat
      541 acataccagc gaaattcgtt gatggccgtt catttctacg acatagatta cggctcaggt
      601 aaacgtaaac agattatcaa agcatatact tccgacacaa tttataccta cgaagactat
      661 aaccttgaaa caaaaggtat gcgattaaaa gattatgaag gacatttttt tagaggtgta
      721 ccagtcaacg aatacgctaa taacgaggag cgaacggggg cttatgagtc tgtacttgat
      781 aatattgacg cctatgattt atctcaatca gagcttgcta actttcaaca agattcagtc
      841 aatgcgttgc ttgtaatagc tggtaatgct tacacaggag ctgatgagaa tgactactta
      901 gatgatggcc gattaaatcc taatggtcgt ttagcgatct caattgggtt taaaaaagcc
      961 caagtgttaa ttttagacga taatcctaat ccaaatggcg ttaaaccgca agcgtacttt
     1021 ctcaaaaaag agtatgatac cgccggtagc gaagcctaca aaaataga
//
LOCUS       DARYNN010000126         1035 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.127, whole genome shotgun sequence.
ACCESSION   DARYNN010000126 DARYNN010000000
VERSION     DARYNN010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1035
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.127"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            <1..>1035
                     /locus_tag="TVB59_002041"
     CDS             <1..>1035
                     /locus_tag="TVB59_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010873.1"
                     /translation="KGINVIALLKGYRRSYHRSSFFIKTGSIVMVLYLAIVSILGLTD
                     YLSMRQYIPTWESSKYYANMACAWSWSYEKDDDKFHEIVIPKLNNLWNSLDDSGAILF
                     NAPNVRKEGMNDDEEYLNQQPFQGNYAYVNKNYLHIANLLDKDTNKIEQYKIHENEWI
                     VFVPEDVKITELDKEKIHEDHIFQNIKKQGTIIETYVRLKDNQSVFSFDSGKRIDEAN
                     LKNYVLVAVNGKELLPDHGIKLSSLVNGQLHPYVKEPSRAYESLKDIIEETESEPFIL
                     YISSVYDDIVSRIDEYKMEASIYVIGLVLSIVILATLLKIDKETYFYNHGQRIDVSRL
                     LGYGFFDIHH"
BASE COUNT          394 a          117 c          193 g          331 t
ORIGIN      
        1 aaaaggaatt aatgttattg ccttattgaa aggttataga agaagttatc atagaagttc
       61 tttttttata aaaacagggt cgattgttat ggttctttat ctagcaattg taagtatttt
      121 aggactcact gattacttga gtatgagaca atacattcca acttgggaaa gctcaaagta
      181 ttatgcaaat atggcttgtg catggtcttg gagttatgaa aaagatgatg ataagttcca
      241 tgaaattgtt attccaaagc tgaataactt atggaatagt ttggacgata gtggagcaat
      301 attatttaat gccccaaacg ttagaaaaga gggaatgaat gatgatgagg agtatctaaa
      361 tcaacaacct tttcaaggta attatgccta tgtaaataaa aattatttac atattgctaa
      421 tctcttagat aaagatacga ataaaataga acaatataaa atacatgaaa atgagtggat
      481 tgtttttgtt ccagaagatg ttaaaattac tgaacttgac aaagaaaaaa ttcacgaaga
      541 tcatattttt caaaatataa aaaaacaagg tacaattata gaaacatatg taaggctgaa
      601 agataatcaa agtgtatttt cttttgatag tggcaaaaga attgatgaag caaacttgaa
      661 aaattatgtt ttggtagcag taaatgggaa agaattactc ccagatcacg gaatcaaact
      721 atcatcttta gtaaatgggc agctacatcc atatgttaaa gagcctagta gggcatacga
      781 gagtttgaag gacataattg aagaaacaga atctgagccg tttatactct atatcagctc
      841 agtttacgat gatatagttt caagaataga cgaatataag atggaggcaa gtatatatgt
      901 tattggtctc gtcttatcta ttgttatttt agcaacgtta ttaaaaatag ataaagaaac
      961 atatttttat aatcatggac aacgaataga tgtttctagg ttgttgggat atggattttt
     1021 tgatatacat cataa
//
LOCUS       DARYNN010000127         1028 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.128, whole genome shotgun sequence.
ACCESSION   DARYNN010000127 DARYNN010000000
VERSION     DARYNN010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1028)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1028)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1028
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.128"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            135..1028
                     /locus_tag="TVB59_002042"
                     /pseudo
     CDS             135..1028
                     /locus_tag="TVB59_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISSeq3 family transposase"
BASE COUNT          349 a          189 c          220 g          270 t
ORIGIN      
        1 ctaacaattg gggggctatt tttatgacat tgagttatga agacaaggtt caaatctatg
       61 agctacggca cattggaaag tccattaaat gcttatcaga aaagtttagt attgcagaat
      121 ctgacctcaa atacatgatt cgcctgattg acaggtatgg gttagccatt gtccaaaaag
      181 gtaagaatag ttattattct ccagaactga agcaagagat aatagataaa gttctgattg
      241 atggtcaatc tcaaaaacag acgtccttag actatgcttt accaaattct agtatgcttt
      301 caaggtggat agcgcaatac aagaaaaacg gctatactat tcttgagaaa agaagaggga
      361 ggccaccaaa gatgggacgt caaccaaaga agactttaga acaaatgaca gagttggagc
      421 gactccaaaa agaattagac taccttagag cggagaatgc tgtgctaaaa aagctgagag
      481 aataccggtt gagggacgaa gcaaagctca aagagcaaca gaaatcatcc aagaattaat
      541 cggtcaattt tctctagcaa ctttgcttga aatccttgat ttatcgcggt caacctatta
      601 ttatcaagtc aagcaactag ctcaagaaga taaggacatg gacttaaagg agctcattca
      661 aggcatctat gatgaacatc atggcaatta tggctatcgt cgcattcatc tggaactaag
      721 aaatcgtggt tttatcgtca atcacaaaaa agtacaacgt ttgatgactg tcatgggctt
      781 aaaagctcgt atccgtcgta agcgcaagta ttcttcttac aaaggtgagg ttggcaaaaa
      841 ggctgataat ctgattaaac gtcagtttga aggttctaag ccctacgaga agtgctatac
      901 cgatgtgacg gaatttacct tacctgaggg gaaactctat ctatcgcctg ttcttgacgg
      961 ctataacagt gagattattg atttcaccct gtctcgatcg cctgacttga agcaagtaca
     1021 aaccatgc
//
LOCUS       DARYNN010000128          996 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.129, whole genome shotgun sequence.
ACCESSION   DARYNN010000128 DARYNN010000000
VERSION     DARYNN010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 996)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 996)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..996
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.129"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            <1..317
                     /locus_tag="TVB59_002043"
     CDS             <1..317
                     /locus_tag="TVB59_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003033282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="HEL1010874.1"
                     /translation="RGDVLLRKFKAESNKINGQIKTIKNELKVVDDKKRSIKRRKDEL
                     KKFIEALFYCLEDYKSIEVDKELVDTLINRIEISKYKQVTIYFKFSFDKDIEKQLEVE
                     HE"
     gene            310..>996
                     /locus_tag="TVB59_002044"
     CDS             310..>996
                     /locus_tag="TVB59_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEL1010875.1"
                     /translation="MNRIAIYLRLSEEDYKKTDESVSIVNQRDYVRNYIENENSLKDC
                     EIEEYIDDGFSATNTNRPSFLRLIDNIKAGRINTIIVKDMSRFSRDYILLGDYLSNIL
                     PFLKIRFIAINDNYDSINEDGNGIDTDIQFKTLYYDLFSKELSEKVKSSFKQLKSQGK
                     NTNWAAPFGYIKDPKDKHHIILDEKTAFIVKEAFDLLLEGYSCNQVANIFNEKDYITC
                     SERKEELKISE"
BASE COUNT          422 a          103 c          189 g          282 t
ORIGIN      
        1 ttagaggaga tgttctttta aggaaattta aagcagaaag taataaaata aatggacaga
       61 taaaaacgat aaaaaatgaa ttaaaggtag tagacgataa aaagaggagc ataaagagaa
      121 gaaaagatga actcaaaaaa ttcatagaag ccctatttta ctgcttagag gattacaaga
      181 gtatagaggt ggataaagaa ctggttgata ccttaattaa ccgtatagaa atctcaaaat
      241 acaagcaagt aactatatac tttaaattta gttttgataa agatatagaa aagcagttgg
      301 aggtagagca tgaatagaat agccatttat ttaagacttt cagaagaaga ttataaaaaa
      361 acggatgaaa gtgtaagtat agtaaatcag agagactatg taagaaatta cattgaaaat
      421 gagaactctc tgaaggattg tgagatagaa gaatatatag atgatggttt ttctgctaca
      481 aatacaaaca gaccttcgtt tttaagactt attgataata taaaagctgg gagaataaat
      541 acgataattg taaaggatat gtcgagattt tcaagagatt atatattgct tggagactat
      601 ctgagtaata tattgccctt tttgaaaata cggtttattg ctatcaatga taactatgat
      661 tcgataaacg aagatggaaa cgggatagat acagatatac agtttaagac cttgtattat
      721 gatttattca gtaaggaatt atcggaaaaa gtaaaaagtt cttttaaaca actcaaatca
      781 cagggcaaga atacaaattg ggcagcacct tttggatata taaaagatcc aaaagataaa
      841 catcatatta tacttgatga aaagacagct tttatagtga aagaagcttt tgacttgctg
      901 ttagagggat attcttgcaa tcaggtagca aatatattca atgaaaaaga ttatataacc
      961 tgttctgaaa gaaaagaaga actaaaaatt tcagag
//
LOCUS       DARYNN010000129          985 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.130, whole genome shotgun sequence.
ACCESSION   DARYNN010000129 DARYNN010000000
VERSION     DARYNN010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 985)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 985)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..985
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.130"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            104..985
                     /locus_tag="TVB59_002045"
                     /pseudo
     CDS             104..985
                     /locus_tag="TVB59_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          349 a          166 c          216 g          254 t
ORIGIN      
        1 aagttacgat gataaattaa gaatatatga actaagaaaa aatgggatgt cttgttcccg
       61 cattggtcaa cagtatgata ttcaggtttc taatctcaaa tacatggtaa agcttatgga
      121 cagatatgga gttgagattg ttagaaaggg taaaaataag tattatcctc cagaattaaa
      181 acaagaaata attgataaag ttcttcttga aggtcagtct caactgtctg tctctcttga
      241 gtatgctctc ccaaatgctg gtatgcttcc caattggata gcgcaataca agaaaaacgg
      301 gtatactatt cttgagaaac aaagagggag accaacgaag atgggccgta aaccaaagaa
      361 aacttgggaa gaaatgacag agctagagcg ccttcaggaa gagctagaat accttagaac
      421 ggagaatgct tatctaaaaa agttgaggga gcttcgttta caggacgaag ccagagaatg
      481 agaaaggcag aaacaattag agagatggtc caagaaggat tccgattaaa cctcctactt
      541 gagatcgcta agatggctcg ttcaacctat tattatcaag tcaagcaatt ggataagtca
      601 gataaagatg aagcaatcaa ctctgaaatc aaagcgattt atgaggagca taagggaaac
      661 tatggttacc gtcgcattca tttagaactc aagaatcgtg ggtttatcgt caatcacaag
      721 aaagtgcaac gcttgatgaa agagatgaga ttagctgctc gaattcgtcg taaacgcagg
      781 tattcctctt acaaaggcga gactggtaag aaggctgata atctgattca acgccagttt
      841 gaagctgcta agccatatga aaaatgttat accgatgtga cagagtttgc tttaccaaac
      901 aacgatgaaa aactttattt agcgcctgtt cttgatggct acaacagtga gattattgat
      961 ttcacactat ctaggtctcc agact
//
LOCUS       DARYNN010000130          958 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.131, whole genome shotgun sequence.
ACCESSION   DARYNN010000130 DARYNN010000000
VERSION     DARYNN010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 958)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 958)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..958
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.131"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            <1..>958
                     /locus_tag="TVB59_002046"
     CDS             <1..>958
                     /locus_tag="TVB59_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hyaluronidase"
                     /protein_id="HEL1010876.1"
                     /translation="QDNQKVRLASNCLGTTRFNQVMIERGDKATDYVAPVVVEGSGES
                     TGVFKSLEEMLSGLQSINLELTDTKNSNLWSKIKLTTNGMLREYHRDHIKTEIVESAD
                     GIAKRIADDTGQKLALINETIKGIKREYQDADRQLSASYQAGIDGLKTQLANDKIGLQ
                     AEIKLSAQGLSQKYDDELRKLYAKITTTSSGTTEAYENKLEGLRAEFTRSNQGMRTEL
                     ESQISGLRSVQQSTAKQISQEIRDRTGAVSRVQQDLASYQRRLQDAEKNYSSLTQTVK
                     GLQSTVSDPSGKIQSRFTQLQNQIDQRVTRDDVMSIINLSGD"
BASE COUNT          308 a          207 c          236 g          207 t
ORIGIN      
        1 gtcaagacaa tcaaaaagtc agattagcca gcaactgtct aggaacaact cgctttaatc
       61 aggttatgat tgagagaggc gacaaagcga ctgactatgt tgcgcctgtt gtcgttgagg
      121 gcagcggtga gtcgacaggt gtgtttaaaa gtcttgagga gatgcttagt ggtctacagt
      181 ctattaattt agagctgaca gataccaaaa actccaatct ttggtcaaaa atcaagctca
      241 cgacaaacgg tatgttacgc gagtatcatc gtgatcatat taaaacagag attgttgaga
      301 gcgcagatgg tattgccaag cggattgccg atgacactgg ccaaaagctg gcactaatca
      361 atgagaccat caaaggtatc aagcgtgagt accaagacgc agatagacag ctatccgcga
      421 gctaccaagc gggcattgat ggcctaaaaa ctcaactggc caatgacaaa atcggtctac
      481 aagctgagat taagctgtca gctcaaggct tgtcgcaaaa gtacgacgat gagctgcgca
      541 agctgtatgc taagattacc accacctcat caggcacgac cgaagcgtac gaaaacaagc
      601 ttgagggctt gcgtgctgag tttacccgta gcaaccaagg catgcgcact gagttagagt
      661 cgcagattag cgggttaagg tctgtgcagc agtcaactgc aaaacaaatc tcgcaggaga
      721 ttagagacag gacaggtgct gttagtcgtg tgcaacagga cttagccagc tatcaaagac
      781 gcttgcagga cgccgaaaaa aattacagca gtttaaccca gacggttaaa ggtctacaat
      841 caactgttag cgatccgtca ggtaaaatcc agtcgaggtt tacacaacta caaaatcaaa
      901 tcgaccaacg tgtgacaaga gatgacgtta tgtcaatcat caacctatcc ggagatag
//
LOCUS       DARYNN010000131          908 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.132, whole genome shotgun sequence.
ACCESSION   DARYNN010000131 DARYNN010000000
VERSION     DARYNN010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 908)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 908)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..908
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.132"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(7..492)
                     /locus_tag="TVB59_002047"
     CDS             complement(7..492)
                     /locus_tag="TVB59_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComX"
                     /protein_id="HEL1010877.1"
                     /translation="MTDDLVRLFDKIKPIIMKLRQHYYIQLWELDDWLQEGRLILYRL
                     LVTYPELIEDEEKLYRYFKTKFSSYLKDVLRQQESQKRRFHKMAYEEIGSVGHAIPAG
                     GLGVDDYVAYQLIVKEVEERLTEGELSQFRALIRGERFEGRRALLRKIGPYFQDFTGE
                     K"
     gene            complement(581..654)
                     /locus_tag="TVB59_002048"
     tRNA            complement(581..654)
                     /locus_tag="TVB59_002048"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(618..620),aa:Arg,seq:acg)
BASE COUNT          274 a          261 c          137 g          236 t
ORIGIN      
        1 ccccttttat ttctcaccag taaagtcctg aaagtaaggt cctatcttgc gaagcaaggc
       61 ccgtctcccc tcaaaccgct ctcccctgat caaagcccga aactgcgaca gctcaccctc
      121 tgtcaatcgc tcctcaacct ccttcacaat caactgataa gccacataat catctactcc
      181 caaaccacct gctggtatcg catggcctac cgacccaatc tcctcataag ccatcttatg
      241 aaaccgacgc ttctgactct cctgctgccg caacacgtcc ttcaaataag aggaaaactt
      301 ggtcttaaaa taacgatata gcttctcctc atcctctatc aattctggat aagtgaccaa
      361 taaccgatac aagatcaacc gcccctcctg taaccaatca tctagctccc acagctgaat
      421 ataataatgc tgtcttagct tcataataat aggcttgatc ttatcaaaca acctcactaa
      481 atcatcagtc attatacttt ctccttttca tgcttagtag ccttattata aggagacaaa
      541 caaaaaaaca acaggacaga aatgtcctgt tgccttgcta tgcaccctag aggagtcgaa
      601 cctctaaccg cctgattcgt agtcaggtac tctatccagt tgagctaagg gtgcttttct
      661 taactattac tatcctacca tactatcccc taaaaagcaa ggctctatac catctggaat
      721 aggtaagtcc actgtggaaa tcatagagct ttttgagtac acaaaaaaga gagcaccaaa
      781 ctgatcctct ctaaatgtcc gttgttagtc aacccactat agttgacata gagccaaact
      841 ccgccagtag gactcgaacc tacgacatca tgattaacag tcatgcgcta ctaccaactg
      901 agctatgg
//
LOCUS       DARYNN010000132          890 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.133, whole genome shotgun sequence.
ACCESSION   DARYNN010000132 DARYNN010000000
VERSION     DARYNN010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 890)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 890)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..890
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.133"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            <1..>890
                     /locus_tag="TVB59_002049"
     CDS             <1..>890
                     /locus_tag="TVB59_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004819958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEL1010878.1"
                     /translation="EEAKNILNELKVPPKQQSDLCGYVILAMADIKKNDEWANATNKW
                     IRIHDVIAFIREFYEVSYAENSRETFRKQAMHHFRNAAFIEDNGKATNSPNYRYRLTD
                     EMLLLVKTFQSSLWEEQKNNFLKSHQNLIDLYSSKKAVRKMPVKINGDDFTFSPGKHN
                     QLQKFIIEEFAPRFAENSECLYVGDTIQKDLVKNEEKLKELGFEITLHDKMPDVVLYS
                     EDKNWIYFVESVTSVGAMEPKRIKEIEEMTENVSAGKIYVTAFLDFKTFKKFSESLAW
                     ETEVWIADMPDHMIHLNGDK"
BASE COUNT          331 a          113 c          183 g          263 t
ORIGIN      
        1 gaagaagcaa agaatatttt gaatgagttg aaagttccac caaaacagca gtcggatcta
       61 tgtggatatg ttattttggc aatggcagat attaaaaaga atgatgaatg ggctaatgca
      121 actaataaat ggataagaat tcatgatgtt attgccttta ttagagagtt ttatgaggtt
      181 tcatatgcag agaatagtag agaaacattc cgtaaacagg caatgcatca ttttaggaat
      241 gcagcattta ttgaagataa tgggaaagca acaaatagcc ctaattacag gtatcgatta
      301 actgatgaaa tgttgttatt agtaaaaaca tttcaatcaa gtctgtggga agaacagaag
      361 aataatttct taaaatctca tcagaactta attgatctat atagctctaa aaaggcggta
      421 agaaaaatgc ctgttaaaat aaacggagat gattttacat tttctcccgg caaacacaat
      481 caattacaga aatttattat tgaagaattt gctccacgat tcgctgagaa ctctgaatgt
      541 ttgtatgttg gtgacacaat tcaaaaggat ttggtgaaga atgaggagaa actaaaagaa
      601 ctcggctttg agataacact ccatgataaa atgccggatg ttgttttata ttcagaagat
      661 aagaactgga tctactttgt tgagtctgta acttctgtgg gtgcaatgga gccaaagcga
      721 ataaaagaaa ttgaagaaat gacggaaaat gtttcagctg ggaaaatata tgtaacagca
      781 tttttagact ttaaaacatt taaaaaattc tcagagtctt tagcttggga aacggaagta
      841 tggattgcgg atatgcctga ccatatgatt catttaaatg gtgataaatt
//
LOCUS       DARYNN010000133          871 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.134, whole genome shotgun sequence.
ACCESSION   DARYNN010000133 DARYNN010000000
VERSION     DARYNN010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 871)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 871)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..871
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.134"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            23..313
                     /locus_tag="TVB59_002050"
     CDS             23..313
                     /locus_tag="TVB59_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010879.1"
                     /translation="MIDFVQIGAFCGAALSILGVWGFIVNPFKKAMEANELAMAQLKD
                     SIKELAYELKNLDRDREITKKIIDRHEERLGRVEDDIIVNKEQIKTLFKKGD"
     gene            316..495
                     /locus_tag="TVB59_002051"
     CDS             316..495
                     /locus_tag="TVB59_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010880.1"
                     /translation="MDKWFKKVAIKTIKTMAQTAVGVIGSSALITDVNWQVVTSTVIM
                     SGIVCVLMNVSDIKE"
     gene            607..>871
                     /locus_tag="TVB59_002052"
     CDS             607..>871
                     /locus_tag="TVB59_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEL1010881.1"
                     /translation="MTFLDKIKQGCLDGWTKYKILPSLTAAQAILESGWGKYAPYNAL
                     FGIKADSSWTGKSFNTKTQEEYQPGVVTDIVDRFRAYDSWEESI"
BASE COUNT          276 a          148 c          209 g          238 t
ORIGIN      
        1 aaacaagatt agaggtggtt agatgataga ttttgtacaa attggtgctt tttgtggcgc
       61 tgctttgtct atcttgggtg tttggggatt tatcgtcaat ccctttaaaa aagccatgga
      121 agctaacgag ctagccatgg cccaactcaa agactcgatc aaggagttag cctacgagct
      181 aaaaaatctt gatcgcgata gggagataac caaaaagatt atcgatcggc atgaggagcg
      241 tttaggacgt gtagaggacg acattattgt caataaagag caaatcaaaa cattatttaa
      301 aaaaggagac taaaaatgga taaatggttt aaaaaagtag caatcaaaac aattaagaca
      361 atggcccaaa ccgctgtagg ggttattgga tcaagcgcat tgattactga cgtcaactgg
      421 caggtggtga cctcaacagt tattatgtca ggtattgtct gcgtcttgat gaatgtgtct
      481 gacatcaagg aatagcatta tgcgagcaat cacacgatta gcaatagtca tagcaatcac
      541 aatactgtat ttaccgctat ctgtgattgc tctgattgtt tatccgtttt tagataagga
      601 ggacagatga cctttttaga taagattaag caaggctgct tagatggctg gaccaagtac
      661 aaaatcttgc catctttaac agcagcacag gcaatccttg agagcggttg gggtaagtat
      721 gccccatata acgctctatt tggtatcaag gcagatagct cttggacggg taagtcattt
      781 aacacaaaaa ctcaggagga gtatcagccg ggtgttgtaa cggatattgt agatcgtttt
      841 agggcctatg atagctggga ggaatccatc g
//
LOCUS       DARYNN010000134          840 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.135, whole genome shotgun sequence.
ACCESSION   DARYNN010000134 DARYNN010000000
VERSION     DARYNN010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 840)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 840)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..840
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.135"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(101..616)
                     /locus_tag="TVB59_002053"
     CDS             complement(101..616)
                     /locus_tag="TVB59_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010882.1"
                     /translation="MKSKKLVFGQIDLNMCRDFDLVQALDYDFKEKKLYNKGRGFAIV
                     LVSIQNLTFAIPLRSNIPKKYQLKYKLRDSKKYGCVEGLDIGKALVVEDPKYILNRTF
                     KLREQVDYFKIVDNDILIVNKLIKAIIDYNQAVANSDQHKLTDPKRFKFSTFPNYTDR
                     LKSITDADYLR"
BASE COUNT          259 a          149 c          136 g          296 t
ORIGIN      
        1 tgtgtgaaac acaaaaaacc gcccagaaat aatctgagcg gttgattttt attttggcta
       61 attcttacta tggtaattgg ttcatgattg tgcgagggtg tcaacgaaga taatcggcat
      121 cggtaatgct ttttaatctg tcggtatagt ttgggaatgt agagaatttg aaacgtttag
      181 gatctgttaa tttatgttga tcactattag ctacagcttg attataatct atgatagcct
      241 ttatcaactt gttaacaata agtatatcat tatcaacaat cttaaaataa tcaacctgct
      301 ctcgtaattt gaacgttctg tttaaaatat attttggatc ttcaaccact agagctttgc
      361 caatatcaag cccctctacg catccgtatt ttttagagtc tcttaattta tattttagtt
      421 gatatttttt aggaatatta cttctcaaag ggattgcaaa agttagattt tggatactta
      481 ccaacacaat ggcaaaacct cggcctttgt tatatagctt cttctcttta aaatcatagt
      541 ctaaagcttg taccaaatcg aaatctcgac acatgtttaa atcaatctga ccgaatacta
      601 attttttact cttcattatt tgccttctaa aaataaaaaa tcctaccaac tgggtattgg
      661 taggacgcat tgccaacggg atacttctgt taacgagcgc gtccctccgc cccctcattg
      721 ccaaaatggc gagagtttaa cgacatggaa aggtcggaac atagagataa tgcttttact
      781 atttatgttc atttacatta ttacataata tgttgcattc gtcaaatata gaatctttaa
//
LOCUS       DARYNN010000135          796 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.136, whole genome shotgun sequence.
ACCESSION   DARYNN010000135 DARYNN010000000
VERSION     DARYNN010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 796)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 796)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..796
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.136"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(<1..>796)
                     /gene="galU"
                     /locus_tag="TVB59_002054"
     CDS             complement(<1..>796)
                     /gene="galU"
                     /locus_tag="TVB59_002054"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEL1010883.1"
                     /translation="LPATKALAKEMLPIVDKPTIQFIVEEALKAGIEEILVVTGKAKR
                     SIEDHFDSNFELEYNLQAKGKTELLKLVDETTAINLHFIRQSHPRGLGDAVLQAKAFV
                     GNEPFVVMLGDDLMDITNPSAKPLTKQLIEDYDCTHASTIAVMRVPHEEVSNYGVIAP
                     QGKAVKGLYSVETFVEKPSPDEAPSDLAIIGRYLLTPEIFAILENQAPGAGNEVQLTD
                     AIDKLNKTQRVFAREFKGERYDVGDKFGFMKTSLDYALKHPQVKDDL"
BASE COUNT          188 a          210 c          198 g          200 t
ORIGIN      
        1 aggtcgtcct tgacctgagg gtgcttgaga gcatagtcaa gtgaggtctt cataaagcca
       61 aacttgtccc caacatcata ccgctctccc ttaaactccc tggcaaaaac ccgctgagtc
      121 ttgttgagct tgtcaatcgc atcggtcagc tgaacctcat tgccagcccc aggcgcctga
      181 ttctccaata tggcaaaaat ctcaggcgtc aacaaataac gtccaataat cgctaagtca
      241 ctaggtgcct catcaggact tggcttctca acaaaggtct ccacactata caagccctta
      301 acagccttcc cttgcggtgc aatcacgcca taattggaaa cctcctcatg cggaaccctc
      361 atcacagcaa tcgttgaggc gtgtgtacag tcataatcct cgataagctg cttggtcaag
      421 ggcttggcac taggattggt aatatccatg aggtcgtctc ctagcatgac cacaaagggc
      481 tcattgccca caaaggcctt ggcttggagg acagcgtccc ctagtcctct agggtggctc
      541 tgacgaatga agtgcaggtt gatggcagtg gtctcatcaa cgagcttgag cagctcggtt
      601 ttgcccttgg cttggagatt gtattcgagc tcgaagttgg agtcaaagtg gtcttcgata
      661 gagcgtttgg ccttgccggt gacgacaaga atctcctcga taccggcctt tagggcttcc
      721 tcgacgatga attgaatggt tggcttatcg acgattggga gcatttcctt ggccagtgcc
      781 ttagtggcag gcagga
//
LOCUS       DARYNN010000136          776 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.137, whole genome shotgun sequence.
ACCESSION   DARYNN010000136 DARYNN010000000
VERSION     DARYNN010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 776)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 776)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..776
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.137"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(<1..265)
                     /locus_tag="TVB59_002055"
     CDS             complement(<1..265)
                     /locus_tag="TVB59_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEL1010884.1"
                     /translation="MTFLDDIKQGCLDGWTKYKILPSLTAAQAILESGWGKYAPHNAL
                     FGIKADSSWTGKSFNTKTQEEYQPGVVTDIVDRFRAYDSWDESI"
     gene            complement(382..753)
                     /locus_tag="TVB59_002056"
     CDS             complement(382..753)
                     /locus_tag="TVB59_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HEL1010885.1"
                     /translation="MFIFLRQLIQTQDGKILFTLGAIAVAMMIDFLTGTVAAKINPNI
                     DFRSKEGINGILRKICSIALMIFFIPLSILLPNDTGVAFLYVMYVGYLLFELKSILEN
                     LNKMGIDVALFKQFIDMFSKK"
BASE COUNT          239 a          177 c          134 g          226 t
ORIGIN      
        1 ggatcgactc gtcccagcta tcataggccc taaaacgatc tacaatatcc gttacaacac
       61 ccggctgata ctcctcctga gtttttgtat taaatgactt acccgtccaa gagctatctg
      121 ccttgatacc aaatagagcg ttatgtgggg cgtacttgcc ccaaccactc tcaaggattg
      181 cctgtgctgc ggtcaacgat ggcaagattt tatactttgt ccagccatct aagcagcctt
      241 gcttaatgtc atctaaaaag gtcatctgtc ctccttatct aaaaacggat aaacaatcag
      301 agcaatcaca gacagcggca catatagcac tgcgattgct aggactattg ctaatcgtgt
      361 gattgctcgc atgagatcct cctatttttt actaaacata tcaataaatt gcttaaacag
      421 tgcgacatca atccccattt tgtttagatt ttctaagatt gattttagct caaagagcag
      481 atagccaacg tacatgacat acaaaaaggc tactcctgta tcatttggca gtaaaatcga
      541 caaagggata aaaaagatca tcagggcaat tgagcaaatt ttgcgcaaaa taccattaat
      601 cccctctttg ctcctaaaat caatgttggg gttaattttt gctgcaacgg tacccgttaa
      661 aaaatcaatc atcattgcga ctgcaattgc tcctaaagta aataggattt taccatcttg
      721 ggtctggatt aattgtctca aaaaaataaa catggatcac ctcactattt gccttt
//
LOCUS       DARYNN010000137          672 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.138, whole genome shotgun sequence.
ACCESSION   DARYNN010000137 DARYNN010000000
VERSION     DARYNN010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..672
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.138"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(<1..>672)
                     /locus_tag="TVB59_002057"
     CDS             complement(<1..>672)
                     /locus_tag="TVB59_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEL1010886.1"
                     /translation="AGKGTRMKSGLPKVLHKVSGLSMLEHVLNSVSALAPQKQLTVIG
                     HQAEQVRAVLGDQSLTVVQEEQLGTGHAVMMAEEELSGLEGQTLVIAGDTPLIRGESL
                     KALLDYHIREKNVATILTANAKDPFGYGRIIRNVAGEVVNIVEQKDANEAEQEVKEIN
                     TGTYIFDNKRLFEALKHLTTDNAQGEYYLTDVISIFKAGQERVGAYLLKDFDESLGVN
                     DRLALA"
BASE COUNT          140 a          183 c          152 g          197 t
ORIGIN      
        1 gctagggcta ggcgatcatt aacccctagg ctctcatcaa aatccttcag caggtaagcg
       61 ccaacccttt cttggccagc cttgaaaata ctgatcacat cggttaggta gtactcccct
      121 tgggcattat cagtcgtgag atgctttaga gcctcaaaga ggcgcttatt gtcaaagata
      181 taagtccctg tgttgatctc cttgacctct tgctctgcct cattagcgtc cttttgctca
      241 acgatattga ccacctctcc tgctacattg cgaatgattc gtccatagcc aaagggatcc
      301 ttggcattgg ctgtgagaat ggttgccaca ttcttttctc tgatatgata gtctagcaga
      361 gccttgagac tttctcctct gatcaagggg gtgtcacctg caatcactag ggtttgtccc
      421 tctaagccag atagctcctc ttctgccatc atgactgcat ggcctgttcc tagctgctcc
      481 tcttgcacca ctgtcagtga ttgatcacct aggacggcac gtacctgctc tgcctgatga
      541 ccgatcactg tgagttgctt ttgaggagct agggctgaga cgctattgag gacatgctcc
      601 agcatgctta agcctgatac cttgtgcagc accttgggaa gccctgattt catgcgggtt
      661 ccctttccag ct
//
LOCUS       DARYNN010000138          650 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.139, whole genome shotgun sequence.
ACCESSION   DARYNN010000138 DARYNN010000000
VERSION     DARYNN010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 650)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 650)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..650
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.139"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            5..613
                     /locus_tag="TVB59_002058"
     CDS             5..613
                     /locus_tag="TVB59_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010887.1"
                     /translation="MNMISVKKNLCRLGVLSSSLLLLTAATTPSVIAFADIQTSAIKN
                     NTDDADGMYFVQSYEMSVEDKELLVRNVKANHPTVSEDFIREVIERQLVGDYTLPEEE
                     TLFRSAWQGVTVDQLGAALDVAIGMALTGGAGSIAAGVLRVGKREAVGRVKSILIKYG
                     LGKMIAEIPVDYMLNLLSPGYHIARYIDSIDTVPNNNRINLW"
BASE COUNT          217 a           81 c          137 g          215 t
ORIGIN      
        1 gtgaatcaat atgatttctg taaagaaaaa tttatgtcgc ttaggtgttt tgtctagtag
       61 tttattactt ttaacagctg caacgactcc atctgtcatt gcttttgcgg atattcaaac
      121 aagtgccata aaaaataata cagatgacgc agatggtatg tattttgttc aaagttatga
      181 aatgtctgta gaagataaag aattgcttgt tcgaaatgtt aaagcaaatc atcctacagt
      241 ttctgaagat tttatcagag aagttattga aagacaatta gtaggtgatt atacattacc
      301 tgaagaagag actcttttcc gctcagcatg gcaaggggtt acagtagatc aattgggagc
      361 agctctagat gtggctattg gtatggcatt aacaggtgga gctggatcaa ttgctgctgg
      421 tgttttgaga gtcggaaaaa gagaagctgt tggtcgggta aaatcaattc taattaaata
      481 tgggctaggt aaaatgatag ctgaaattcc agtcgattac atgttaaatt tattatcgcc
      541 aggatatcat atagctagat atattgatag tattgataca gttcctaata ataatagaat
      601 taacctttgg taagttagga aatttagtac tgtgaaaaaa atttatattt
//
LOCUS       DARYNN010000139          619 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.141, whole genome shotgun sequence.
ACCESSION   DARYNN010000139 DARYNN010000000
VERSION     DARYNN010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 619)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 619)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..619
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.141"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            186..>619
                     /locus_tag="TVB59_002059"
     CDS             186..>619
                     /locus_tag="TVB59_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HEL1010888.1"
                     /translation="MRYTLNKNKRARNYGLCSAAIALAAVASLGTAGSAKAEEAKTLD
                     QLPNPEEQILYNYWDTNDQKAREYLGDLYGFLKSYLGELEKKAKEPGPAGPKGEKGEK
                     GEKGETGPMGPQGLKGEDGKDGAPGEKGEKGDPGIQGPKGEKG"
BASE COUNT          245 a          110 c          149 g          115 t
ORIGIN      
        1 caatgtcaat aacatcaatc aaaaatcaga cgattaggat tttgattaaa aaaaaaaaaa
       61 aacgaaacca aagattgaaa ttgatagata gctattccca ctctaatagt ggacatgtta
      121 gaatttcctt tgggaaagga agttacagga aactaagact gtttctacca caaaaggaga
      181 gaaagatgag atacacatta aacaaaaaca agcgtgctcg taactacggg ctatgctcag
      241 cagctatcgc tctagcagca gtagccagcc taggaacagc tggcagcgct aaagctgagg
      301 aagcaaaaac attagaccaa ctacctaatc cagaagagca aattctatat aattattggg
      361 acacaaatga tcagaaagca agagaatatc ttggagacct atacggtttc ctaaaatctt
      421 atttaggaga gttggaaaaa aaagctaaag agcctggacc tgctggacct aaaggtgaaa
      481 aaggcgaaaa aggcgaaaaa ggcgagaccg gtccgatggg gcctcaaggc ctaaagggtg
      541 aggacggaaa agacggcgca cctggagaaa aaggagaaaa aggtgatccg ggtatccaag
      601 gccctaaggg ggaaaaggg
//
LOCUS       DARYNN010000140          618 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.142, whole genome shotgun sequence.
ACCESSION   DARYNN010000140 DARYNN010000000
VERSION     DARYNN010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 618)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 618)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..618
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.142"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            <1..219
                     /locus_tag="TVB59_002060"
     CDS             <1..219
                     /locus_tag="TVB59_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL1010889.1"
                     /translation="MSRKGNSPDNGMMESFFGILKSEMFYGFEKSYHSLDELEQAITE
                     YIFYYNNKRIKTKLKGLSPVQYRTKSFH"
     gene            221..>618
                     /locus_tag="TVB59_002061"
     CDS             221..>618
                     /locus_tag="TVB59_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HEL1010890.1"
                     /translation="MSCPTFGGQYKVSQTLGSDFDLPYYIYSKIKRNKTEKVISPLKI
                     GLKITNACYFRCPYCFVSKEEDYLLFDHLKIIIDKLPQLPFEVYLTGGEATLHPEFPK
                     IVDYLVDLGILVKLHTTGVITEKSRNYIIS"
BASE COUNT          213 a          103 c          102 g          200 t
ORIGIN      
        1 atgtctcgca agggtaacag ccctgataat gggatgatgg aatccttctt tggcatttta
       61 aagtcagaga tgttctatgg ctttgagaaa tcctaccact cactggatga gctcgaacaa
      121 gcaatcactg aatacatctt ttactacaac aataaacgaa tcaaaactaa actaaaagga
      181 cttagccctg tgcaatacag aactaaatcc tttcactaat atgtcgtgtc caacttttgg
      241 gggtcagtac aaagtatcac aaactctggg gagtgatttt gatttacctt attatatata
      301 ttccaaaata aaaagaaata agacggaaaa agttatatct cctcttaaaa ttggtttgaa
      361 aattaccaat gcatgctatt ttagatgtcc gtactgtttt gtatcaaaag aagaagatta
      421 cctcttgttt gatcatttga aaataataat agataaacta cctcaacttc cgtttgaagt
      481 ttatctaact ggtggtgaag ctactttaca tcctgagttt cctaaaattg tggattatct
      541 tgttgatcta ggaattcttg taaaacttca tacaactggg gtaattactg aaaaaagtag
      601 aaattatatt atttctaa
//
LOCUS       DARYNN010000141          570 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.143, whole genome shotgun sequence.
ACCESSION   DARYNN010000141 DARYNN010000000
VERSION     DARYNN010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 570)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 570)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..570
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.143"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(<1..>570)
                     /locus_tag="TVB59_002062"
     CDS             complement(<1..>570)
                     /locus_tag="TVB59_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HEL1010891.1"
                     /translation="FKGFEDINDRDLRVGTFYYPKNEERKHLILLVCGYEESYLDFKS
                     EIFFWLKNGYTVFCYDVRGTGRSQGRKVGGFTQFLKDCLLSIEYIEKNETFKKVSLVG
                     HSMGGFAVATSLQFKTNIIDNSVIISGFDYPSEFVRKSVTNISFIFTWPIEISIKLIE
                     FLKFGNLSFLGSVSSINIFNKPVLIIQSSD"
BASE COUNT          202 a          112 c           58 g          198 t
ORIGIN      
        1 atcactagat tgaattatta gtacaggttt attaaatata ttaatgctac taactgatcc
       61 caaaaaagac aggttcccaa atttcaaaaa ttctataagt tttatggata tttctattgg
      121 ccatgtaaaa ataaacgaaa tatttgttac actttttctt acaaattcag atggataatc
      181 aaatcctgaa atgattacac tgttatctat tatattggtt ttgaattgta acgaagtcgc
      241 tactgcaaaa cctcccatac tatgccccac taaagatacc tttttaaaag tttcattttt
      301 ttcaatgtat tcaatggaca ataagcaatc cttcaaaaac tgagtaaaac ctccaacttt
      361 tcttccctga cttcttccag ttcctctaac atcatagcaa aacacagtat atccattttt
      421 cagccaaaaa aatatctcgg atttaaagtc taaataggat tcttcatatc cacaaactag
      481 taatatcaaa tgtttccttt cttcattctt gggataataa aatgtcccta ctctcaaatc
      541 acgatcatta atatcttcaa atcccttaaa
//
LOCUS       DARYNN010000142          569 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.144, whole genome shotgun sequence.
ACCESSION   DARYNN010000142 DARYNN010000000
VERSION     DARYNN010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..569
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.144"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            <1..318
                     /locus_tag="TVB59_002063"
     CDS             <1..318
                     /locus_tag="TVB59_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1617 family protein"
                     /protein_id="HEL1010892.1"
                     /translation="EAKLREYAKDEVDIIDQYAAKNDKGKWLVDDKGNAKLADVTKAA
                     ELNELLDELANEPIVIKGHEYSKRFIDFLEYLAEAEDEFTGAEIILIDNILEQYEANK
                     KGE"
     gene            322..>569
                     /locus_tag="TVB59_002064"
     CDS             322..>569
                     /locus_tag="TVB59_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1366 domain-containing protein"
                     /protein_id="HEL1010893.1"
                     /translation="MRNWKVTGKYPQFDSTGAVASTHVIITAEDGSVISQPIKQDLTS
                     TNDTEIIKATLEEFKKSEYVEIAMGEAVQKVDDLEKLS"
BASE COUNT          203 a          112 c          134 g          120 t
ORIGIN      
        1 gaggctaagc taagagagta cgctaaggac gaggttgata ttattgatca gtacgctgct
       61 aaaaacgaca aaggcaagtg gttggtcgat gacaaaggca acgctaaatt agctgatgtc
      121 acaaaagcag ctgagctaaa cgagctttta gacgagttag ccaacgagcc tatcgtcatc
      181 aaaggccatg agtactctaa gcgatttatc gactttttgg agtatttggc cgaggccgaa
      241 gatgagttta caggggccga aatcatctta atcgacaaca ttttagagca gtacgaagca
      301 aataaaaaag gagagtaaat tatgcgcaat tggaaagtca caggaaaata cccacaattt
      361 gacagcacag gagcagtcgc aagcactcac gttattatta cagcagagga tggctcagtc
      421 atctctcaac caatcaagca ggacttaacc tcaactaatg acacagagat catcaaagct
      481 accttggaag aatttaaaaa atccgaatac gtggaaatcg ccatgggcga agcggtgcaa
      541 aaagtggacg acttggaaaa actatcgca
//
LOCUS       DARYNN010000143          550 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.145, whole genome shotgun sequence.
ACCESSION   DARYNN010000143 DARYNN010000000
VERSION     DARYNN010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 550)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 550)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..550
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.145"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(326..>550)
                     /locus_tag="TVB59_002065"
     CDS             complement(326..>550)
                     /locus_tag="TVB59_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1010894.1"
                     /translation="IQGQGEHGHKGHHGKDAKPSAPKADSKSTAKAMAPAAQKGTLPA
                     TGETNHPFFTLAALGVIASAGMLTLKGKKN"
BASE COUNT          139 a           95 c          126 g          190 t
ORIGIN      
        1 tatttgatga tctagaaata gtatcataac tatcttgtta aagaggttga agaaattagc
       61 gcatagaaaa aacgtatcag ttacgattat agtctagttt gtctttatga aatatagata
      121 acactgtaca atccttttct tttattgtac gactttatac aaagaaaagc ccttggaaat
      181 tattttctaa ggactttttt caatttgaga ggctggtgat agcctctttt tgaacttagg
      241 tcatcttctt agggcaatgc tgcctgaaga gatgagaaaa gctgttacta gctcattgcc
      301 taaggggaaa ggtgcaatgg ctggtttagt ttttcttgcc ttttaatgtt agcatgccgg
      361 cgctagcgat aacaccaagg gctgcaaggg tgaagaatgg gtgatttgtc tcccctgtag
      421 ctggtagtgt gcccttttga gctgctggcg ccatagcttt tgctgttgat ttagaatctg
      481 ctttaggtgc tgatggctta gcatcttttc catggtgacc cttatgtcca tgctcgcctt
      541 ggccttggat
//
LOCUS       DARYNN010000144          550 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.146, whole genome shotgun sequence.
ACCESSION   DARYNN010000144 DARYNN010000000
VERSION     DARYNN010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 550)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 550)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..550
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.146"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            <1..375
                     /locus_tag="TVB59_002066"
     CDS             <1..375
                     /locus_tag="TVB59_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1010895.1"
                     /translation="FRRGETYTISFSQTCELLKKVAITLTQANNKGVKLVLTPTKAKM
                     EAQTFNLSKDKEVISVYPLSYRAALTGDWYKSKQVDLNAAEVQNLALEMAYRDVVDSN
                     NASLVLDWSENPDVIFDGNGGS"
     gene            375..>550
                     /locus_tag="TVB59_002067"
     CDS             375..>550
                     /locus_tag="TVB59_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HEL1010896.1"
                     /translation="MSETISAIVVHKSMTKNEWESSDIILPQGQLVYESDTGHSKFGD
                     GKNRYADLIYQGGPP"
BASE COUNT          175 a           95 c          136 g          144 t
ORIGIN      
        1 tttagacgcg gcgagacata cacgattagc tttagccaga cctgtgagtt gctcaaaaaa
       61 gtggctatca cgctgacgca agctaataat aagggagtta aactggtact gacacctacc
      121 aaagctaaga tggaggcgca gacctttaat ctaagtaaag ataaggaggt catcagcgtc
      181 tatcctttga gctacagagc cgctttaact ggtgactggt ataaatctaa gcaagttgac
      241 ttaaatgcgg cagaggtcca aaatttggct ctggagatgg cttatagaga cgtagttgat
      301 agcaataatg ctagtttagt tttggattgg tcagaaaatc cagatgttat ttttgatgga
      361 aatggaggta gttaatgtca gagactatat cagctatagt tgtgcataaa agcatgacaa
      421 aaaacgagtg ggagtctagt gacatcattt tgccacaagg ccagctcgtc tatgagtctg
      481 acacaggcca tagtaaattt ggcgacggta aaaatagata tgcagatttg atctatcaag
      541 gtgggccacc
//
LOCUS       DARYNN010000145          547 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.147, whole genome shotgun sequence.
ACCESSION   DARYNN010000145 DARYNN010000000
VERSION     DARYNN010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 547)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 547)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..547
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.147"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            87..>547
                     /locus_tag="TVB59_002068"
     CDS             87..>547
                     /locus_tag="TVB59_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002948623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEL1010897.1"
                     /translation="MKIVIIGYSGSGKSTLANVLGQHYNCAVLHLDKIHFASNWQERT
                     VSQMVSDISTFMSQKHWIIEGNYSSCLYEERMREADHIIYFNFNRFNCFYRAFKRYLK
                     YRGQTRPDMAENCNEKFDVEFMKWILLDGRSKNNLNNYKAVIKQYPHKTIV"
BASE COUNT          200 a           73 c           94 g          180 t
ORIGIN      
        1 gcttgtctaa agaggatttg tccccaaaat atattcttta tgctataata taagtcaaag
       61 tacagcattg acaaaggaga caaagattga aaattgtaat aattggctat agtggttctg
      121 gaaagtcgac tttagcaaat gttttaggtc aacactacaa ttgtgctgta cttcatttag
      181 acaaaattca ttttgcatca aactggcaag agcgaacagt tagtcaaatg gtctctgata
      241 tatcaacatt tatgtcacaa aaacattgga ttattgaagg taattattca agctgtcttt
      301 atgaagagcg tatgagagag gctgatcaca ttatatattt taactttaat agatttaatt
      361 gtttttaccg agcttttaag cgatatttaa aatatagggg acaaacacgt cctgatatgg
      421 ctgaaaactg taatgaaaaa tttgatgttg aatttatgaa atggattctg ttagacggac
      481 gctcaaaaaa taatttaaat aactataaag cagttattaa acaatatcct cataaaacaa
      541 tcgtttt
//
LOCUS       DARYNN010000146          437 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.149, whole genome shotgun sequence.
ACCESSION   DARYNN010000146 DARYNN010000000
VERSION     DARYNN010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.149"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(68..139)
                     /locus_tag="TVB59_002069"
     tRNA            complement(68..139)
                     /locus_tag="TVB59_002069"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(104..106),aa:Arg,seq:ccg)
BASE COUNT          144 a           82 c           64 g          147 t
ORIGIN      
        1 attggtagat tttctgtcta acttttgggg tgcgggtcat ttaataggct tttttatatc
       61 gtttctatcc accttgaggg aatcgaaccc ccatctcaag aaccggaatc ttgcgtgata
      121 tccattacac taaaggtggc acctttaacc ataccactac agtatagcat aaaagtggat
      181 attttaaaat ccttttttct aaaaagatca caccatacac atgacgaaaa tgcatgtcat
      241 tattttctag tcatatgcat tttatcacta tatttttaat attttgacat catcagtggt
      301 tcaaatacag tttagttata ccataaatgt tcttgaaaaa acacattgat tacgaaaatg
      361 ctaccagaaa atgtcagttt ctccatgcat tggtatgcta aaaaaatact ataaaaagct
      421 gagcaattac ccagctt
//
LOCUS       DARYNN010000147          418 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.150, whole genome shotgun sequence.
ACCESSION   DARYNN010000147 DARYNN010000000
VERSION     DARYNN010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 418)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.150"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            <1..>418
                     /locus_tag="TVB59_002070"
     CDS             <1..>418
                     /locus_tag="TVB59_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_115223326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hyaluronoglucosaminidase"
                     /protein_id="HEL1010898.1"
                     /translation="KLASSKADKSAVYLKAESKIELDKKLSLTGGVMTGQLRLKPNSG
                     IKHSSSVGGAINIDMSKSTGAAMVMYTNKDTTDGPLMILRSDKDTFDQSAQFVDYSGK
                     TNAVNIVMRQPSAPNFSSALNITSANEGGSAMQIRG"
BASE COUNT          142 a           77 c           91 g          108 t
ORIGIN      
        1 ccaaattagc atcaagcaaa gcagataaaa gcgctgttta cttaaaagca gagtcaaaaa
       61 tagagctaga caaaaaattg agtttgacag gtggcgttat gacaggccaa ctacggctta
      121 aacctaatag tggtattaag cactcatctt ccgtaggagg agcgattaac attgatatgt
      181 ctaaatcaac aggtgctgct atggtgatgt atacaaataa agatactact gatggaccat
      241 tgatgatttt acgctctgac aaagatacgt ttgatcagtc agctcaattt gtggattaca
      301 gcggtaagac taatgctgta aatattgtaa tgcgccagcc aagcgcacct aatttttcct
      361 cggcacttaa tataaccagt gccaacgaag gcggtagtgc gatgcaaatt agaggcat
//
LOCUS       DARYNN010000148          414 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.151, whole genome shotgun sequence.
ACCESSION   DARYNN010000148 DARYNN010000000
VERSION     DARYNN010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 414)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 414)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..414
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.151"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            <1..333
                     /locus_tag="TVB59_002071"
     CDS             <1..333
                     /locus_tag="TVB59_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronoglucosaminidase"
                     /protein_id="HEL1010899.1"
                     /translation="THENPNVEASYDENAAALSIDIVKKANGVGTAAQGIYINSTSGT
                     TGKMLRIRNLNDDKFYVKPDGGFYAKETSQIDGNLKLKDPIANDHAATKAYVDGEIKK
                     IKALLTAK"
BASE COUNT          152 a           82 c           91 g           89 t
ORIGIN      
        1 acgcacgaaa acccaaacgt tgaggcaagt tacgatgaaa acgctgcagc gttatctatt
       61 gatattgtca aaaaggcaaa cggtgtagga acagccgctc agggaatcta cattaactca
      121 acctcaggca caactggtaa aatgctcaga atcagaaacc ttaatgatga taagttctac
      181 gtcaagcctg acggtggttt ttatgccaag gaaacttcgc agattgatgg caacctgaaa
      241 ctcaaggatc ccatagcgaa tgatcatgcg gcaaccaaag cttatgttga tggtgaaatc
      301 aaaaaaataa aagcactctt aacggctaag taaatgtaaa aaggaggaga tatgagcaga
      361 gacccaacat taacattaga cgagtcaaat ttaacgatcg gctcagatgg acgt
//
LOCUS       DARYNN010000149          407 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.152, whole genome shotgun sequence.
ACCESSION   DARYNN010000149 DARYNN010000000
VERSION     DARYNN010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 407)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 407)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..407
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.152"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            complement(<1..>407)
                     /locus_tag="TVB59_002072"
     CDS             complement(<1..>407)
                     /locus_tag="TVB59_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronidase"
                     /protein_id="HEL1010900.1"
                     /translation="AGGIDAKMSAKEIISAINLNGYGVRISGERIALDGNTTVNGAFG
                     AKLGEFIKLKADQIIGGTIDAAKIRVINLNASSIVGLDANFIRAKIEHTITSLLEGKV
                     IRARNGAMMIDLNSAKMDFNSNATINFNNKDNAL"
BASE COUNT          113 a          103 c           72 g          119 t
ORIGIN      
        1 agcgcattgt ccttgttgtt aaagttaatg gtagcattgc tattaaaatc cattttagcc
       61 gagtttaaat caatcatcat cgctccgttg cgagctctga taactttacc ctcaagcaaa
      121 cttgtaatcg tatgttcaat tttagccctg ataaagttag catctaagcc gacaatgctg
      181 ctagcgttaa gattgatcac tctaatctta gcagcgtcaa tcgtaccacc aatgatttga
      241 tcagctttga gcttaataaa ctcaccgagc ttagccccaa atgccccatt gacggtcgta
      301 ttaccgtcca gagcaatacg ctcgccagag atccgcacgc catagccatt aagatttatc
      361 gctgagataa tctctttagc gctcatctta gcgtcaatac caccggc
//
LOCUS       DARYNN010000150          407 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.denovo.153, whole genome shotgun sequence.
ACCESSION   DARYNN010000150 DARYNN010000000
VERSION     DARYNN010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 407)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 407)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..407
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.denovo.153"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            <1..>407
                     /locus_tag="TVB59_002073"
     CDS             <1..>407
                     /locus_tag="TVB59_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronidase"
                     /protein_id="HEL1010901.1"
                     /translation="AGGIDAKMSGSEIISAINLNTYGAVIAGKHIALDGNTTVNGTFT
                     TKIAEAIKIKADQIIAGTLDASKARIINLNASSIVGLDANFIRAKIEHTITSLLEGKV
                     IRARNGAMMIDLSNSKIDFNSNATINFNNKDNA"
BASE COUNT          127 a           86 c           87 g          107 t
ORIGIN      
        1 gctggtggga ttgatgctaa aatgtctggc agcgagatta tctcagcgat taatctcaat
       61 acgtatggcg cagtcattgc aggtaaacac atcgctcttg atggcaatac aacggtcaat
      121 ggcactttta ccactaagat agccgaggct atcaaaatca aggctgatca gattatcgca
      181 ggtactttag atgcctcaaa ggctcgtatc attaatctaa acgctagcag cattgtcggc
      241 ttagatgcta attttatcag ggccaaaatc gagcatacga tcacaagttt gctcgagggc
      301 aaagttatca gagctcgcaa cggagcgatg atgattgact tgtcaaactc taagattgac
      361 tttaacagca acgctaccat taactttaat aacaaagaca acgcttt
//
LOCUS       DARYNN010000151         5912 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35849016-rid18537803.guided.083, whole genome shotgun sequence.
ACCESSION   DARYNN010000151 DARYNN010000000
VERSION     DARYNN010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35849016
            Sequence Read Archive: SRR25004119
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5912)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5912)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787464.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787464.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 21:43:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,078
            CDSs (total)                      :: 2,035
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 36 of 88
            Pseudo Genes (internal stop)      :: 26 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5912
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35849016-rid18537803.guided.083"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: SD"
                     /collection_date="2021-09-30"
                     /collected_by="South Dakota State University Animal
                     Disease Research and Diagnostics Laboratory, Brookings,
                     SD"
     gene            354..2075
                     /locus_tag="TVB59_002074"
     CDS             354..2075
                     /locus_tag="TVB59_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1010902.1"
                     /translation="MLTLIVQHIKQKKWIYILIAMTLVIYDASLVIPTRVIQDLVDLM
                     SRHQLSSGALVRHVIILLATAVVSYGVAYLWHLHLFQEAVHFKFDIQQRAFRKLVFMR
                     TPFYEKFRSGDMITRFSTDVEALMDLIGYGLMIILYAGGMIAFIIPTMFLISWKMTLI
                     GIVPILLMMVMIYGVTKKQEHLVEEAREAISSLSDEVLETVEGIRVMRAYSKKDYLAL
                     HFAQKTQNLADKWNQVAKYRALYFPLYSVMIAISTVIILMVGLQLIASSEVTLGQVIA
                     LQLYLVSLVEPFGMLSDFILVYQTGKTSFGKINELIETSDDMEPDGQLELESFDQIAF
                     IDYSFTYANSSRPSLEKINLTLKKGQTLGIVGKTGSGKTTLVRQFLRQYPLGQGQLMI
                     NHRSVLDYKRQSLERQIGYVPQEHILFSKTVAQNIAMGKKAATTEEILEAIETAAFTR
                     DVQGMAKGLDTEIGERGLSISGGQKQRISIARAFLSQPDLLILDDSLSAVDARTETDI
                     IRHIQDERKGKTTLIVSHRLSAIQHADWVIVLDQGQIVEEGQPQQLLAQKGWYYEQYQ
                     RQQAQEV"
     gene            2077..3240
                     /locus_tag="TVB59_002075"
                     /pseudo
     CDS             2077..3240
                     /locus_tag="TVB59_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677880.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            3392..4168
                     /locus_tag="TVB59_002076"
     CDS             3392..4168
                     /locus_tag="TVB59_002076"
                     /inference="COORDINATES: protein motif:HMM:NF022077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HEL1010903.1"
                     /translation="MAEVITIANRKGGVGKTTTTLNLAYSLKELGKKVLVIDLDPQAN
                     LTRCFDMGNTENIKTIGHLLMVELEEEESYLVEGYTKSYDEIDIIPSSIFLSAVETQM
                     RAETGSERILSEIIRRVKENYDYILIDTSPSLSVLTINALCASDSVLIVADTQLFAVV
                     GINELLKTVQKIKKRVNPKLKVQGILLTMCENRTNLSKTLMEQVEEMFQKKIKVFQTK
                     IPKTVKVGEAIYSGQSIKKYAKGSSVDIAYDNLAKEICYE"
     gene            4161..5126
                     /locus_tag="TVB59_002077"
     CDS             4161..5126
                     /locus_tag="TVB59_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003033515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB N-terminal domain-containing protein"
                     /protein_id="HEL1010904.1"
                     /translation="MSKKLLKREITDAVDFLLDDGNALEQGNIQNIELDLLENYHNHP
                     FTLYTGKRLDDMVESIKENGVLNPIIVLKKDNNYEILSGHNRVNAARITKIKSIPCIV
                     KENLTDKEAYTYVIETNLIQRSFSDLLPTEKALVLKMRYEKIASQGKRNDLQKEINNL
                     DQGIIEKESKEEDKIDSRKTLGKEYNLSGASIARYLRLNELSKSWKKDVDEDKIGLTM
                     AVDLSYLSKEIQEYLYQKCEELELSLKPSDAKALHLMNRQEDLNQEMVITYLLNLKKT
                     KVKKYQNIKLSQSVYKKFFHDERKEDVEEIIEKALEIYFKEYIGQ"
     gene            5222..5881
                     /locus_tag="TVB59_002078"
                     /pseudo
     CDS             5222..5881
                     /locus_tag="TVB59_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037566.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Bro-N domain-containing protein"
BASE COUNT         1998 a          933 c         1298 g         1683 t
ORIGIN      
        1 tcaacgatag cgtttgctaa tcactgaaaa cgtttaaaat gcaaacattg gaagcgtttt
       61 ttgtaaaaaa atagaagaac tatccaaaaa aggctttaca agcccagtat tctatgataa
      121 gatgttaggc agattaaaag aaaggagaaa ttaataatga tccgtttcat tcaactattt
      181 aaccattatt acgatagtct cctttctaac caaaacagtt agtttctttt agtttcacta
      241 aatagaaata gtagagcccg cggtaggaag gatatcttat tgcgggcttt ttgtgtgcaa
      301 aaatcctatt ttaagacagc ttgaaatagg ttagttcaga aatggaggat atgatgctga
      361 ccttaattgt tcaacatatt aagcaaaaga aatggattta tatccttatt gcaatgactt
      421 tagtgatata tgatgcctca cttgtgatac caacaagggt tattcaagac ttggttgatt
      481 tgatgtcaag gcatcagcta agctcagggg cattggtgag gcatgttatc attcttttgg
      541 ctacggcagt agtgtcttat ggggttgctt atttgtggca tcttcattta tttcaggagg
      601 cagttcattt taagtttgat attcagcagc gtgcctttcg aaagcttgtt tttatgagaa
      661 cgccttttta tgagaaattt cgctcaggtg acatgatcac gcgtttttca acagatgtcg
      721 aagcacttat ggaccttatc ggctatggct tgatgattat cctatatgct ggtggtatga
      781 ttgcttttat tattccgacc atgtttttga tttcttggaa aatgaccttg ataggaatag
      841 taccgatttt gcttatgatg gtgatgatct atggtgtgac gaaaaagcaa gagcatttgg
      901 ttgaagaggc gcgtgaggcg atttcaagcc ttagtgatga ggtactagaa accgttgagg
      961 gcattagagt gatgcgtgct tacagtaaaa aagattattt ggcacttcat tttgctcaaa
     1021 agactcagaa tttggcagat aaatggaatc aggtggccaa gtatcgtgcc ttgtactttc
     1081 ctctttacag cgtcatgatt gccattagta cagtaatcat tttaatggta ggcctacagc
     1141 tcatagcaag ctcagaggta acacttggtc aagtcattgc gctgcagctt tatctggtgt
     1201 ctttggtgga gccctttggc atgctgtcag actttatttt ggtttatcag acaggaaaga
     1261 cctcttttgg taagattaat gaactcatcg aaacaagtga tgatatggag cctgatggcc
     1321 agcttgagtt agagagcttt gatcagattg cttttataga ctatagcttt acctatgcca
     1381 atagttctag gcctagctta gaaaagatca atttaaccct gaaaaaggga caaaccttag
     1441 ggattgttgg taaaacaggc tctggtaaaa caacccttgt caggcagttt ttgagacaat
     1501 accctcttgg gcaggggcag ctgatgatta atcatcgtag tgtcttggat tataagcgtc
     1561 aatcacttga gcgtcaaatt ggctatgtgc cacaggagca tatcctgttt tcaaaaacgg
     1621 ttgctcaaaa cattgcgatg gggaaaaagg cagctacaac tgaggaaatc ttggaggcga
     1681 ttgaaactgc ggcctttacg cgtgatgttc aaggaatggc aaagggcttg gatactgaga
     1741 ttggagagcg tggtctgtct atttcaggag gtcaaaagca gcgtatttcg attgccagag
     1801 cctttttgtc ccagccagat ttgctgattt tagatgattc cctgtcggca gttgatgcta
     1861 gaacagagac tgatattatt cgacacattc aagacgaaag aaagggaaag acaacactta
     1921 ttgttagcca tcgcttgtct gcgattcagc atgccgattg ggttattgtt ctggatcagg
     1981 ggcagatagt agaggaaggt cagccccaac aacttttagc tcagaagggc tggtattatg
     2041 aacagtacca gcgtcagcag gctcaggagg tttaagatga ccctatttat aaaattaata
     2101 aaagaaatta aagctgtgac cttggctttt tccctggcaa taggcttttt gctagtggca
     2161 acagctggag gtcagatggc tcccttattg ttgcaacaaa cgattgatca ttacttgact
     2221 ccgatagcta gaggaaaaga ggtaccgatt gaaggctttc agcgcttgct cctgctgtat
     2281 ttgctgttaa ttgtgataac agcagttttg cgttatatct cttatcgaat gctggtttat
     2341 tcctctaata ggatcgttgc taatcttcgt aatcgagcct ttgatgtcat gcagaggctg
     2401 ccgatagctt attttgatca tcagcctgca ggaaagattg caactaggat tgttaatgat
     2461 actgaaaccc tgaagaatca attttatgat aaccttttgt ctcaaattat tgtcagtctt
     2521 tcacaaatta tttttattta tgtggtgatg atttaccttg atgtgaagtc aggcttgctg
     2581 ttgctgctta ttatgccact cttttatggc atgcaatggc tgtataaaag cttgactgac
     2641 cagccaatga aggattttta tcaggctagg agcgctgtca acacacaagt caacgaaacc
     2701 atgaatggtg tttctattat tcagctttat catcaagagg atacgatctt agaggaattt
     2761 gaagagcaga tccaccagat gaaaacagct gatgatagga ttatttttgc agagtcagtt
     2821 gcttcatgga ccctgacgga attggtaaag tatggcatga ttgccgctat tttggctgtt
     2881 attggttacc agttcttgca ggggagatca ggcatcacag ttggtaagct ctttatttac
     2941 gtcaattatt tgctgcgctt gtttgattta ttaagtatgc tggttaggca gctacctaat
     3001 attcagcgct caacagcgac aggaacgcgc ctaatgaagc tgcttgaggc gcagacagag
     3061 ccggataaag cacgagcaat tgagctaaca gatggtactg tggattttac caaggtgtat
     3121 tttgcttacg aaaatggcaa gacagtttta tctgatatta ccattcatgc tgataaaggg
     3181 gagacggttg ccctagtagg gcatactggc tctggggaca atgctataat gatgatagta
     3241 caataaatcc aagtaaaatc aatggttaaa ggcttccgca aaacttttaa acttgatgat
     3301 ggattgaggc tatcatcttt ttttatatct aaaattatat aaaagtatag cataaaatga
     3361 aatctctgta tagagaagaa ggagggactt tatggcagaa gtgataacca tagccaatcg
     3421 aaaaggcgga gttggaaaaa caactacaac tctaaacctt gcctattcac taaaagaact
     3481 ggggaaaaaa gtattagtca ttgaccttga tccacaagct aatcttacaa gatgttttga
     3541 tatgggaaat acagaaaata taaaaaccat agggcatttg ttaatggtag aactggagga
     3601 agaagaaagc tatttggtag agggctatac caaatcttat gatgagatag atattatccc
     3661 ctcaagcatt ttcttatccg ccgttgaaac acaaatgaga gcagaaacag gaagtgaacg
     3721 tatattatcg gaaattatta ggagggtaaa agagaattat gactatattc tcatagatac
     3781 atcaccatca cttagtgttt tgactataaa tgctctttgt gcctcagaca gtgtccttat
     3841 agtagcggat acacagctgt tcgcagttgt tggaatcaat gaacttttaa aaactgttca
     3901 aaaaataaaa aagagagtga atccgaaact gaaagtgcag gggattttac taaccatgtg
     3961 tgagaataga accaatctgt ccaaaacact gatggagcaa gtagaagaaa tgttccaaaa
     4021 gaaaatcaag gtctttcaaa ccaaaattcc gaaaacagtt aaagttgggg aagccatcta
     4081 tagcgggcaa agcataaaaa aatatgcaaa aggcagtagt gtagacattg cctatgacaa
     4141 tctggcaaag gagatctgct atgagtaaaa aacttctaaa gagagaaatc accgatgccg
     4201 tagatttttt gcttgatgat ggaaatgcct tggaacaagg aaatatacag aatatagaac
     4261 ttgatttgct tgaaaattat cataatcatc cgtttacttt atatacaggt aagagattag
     4321 acgatatggt agagagcatt aaggaaaacg gagttcttaa tccaattatc gtcttgaaaa
     4381 aagataacaa ctatgaaata ctttccggac acaatagagt aaatgcagca agaattacaa
     4441 aaataaaaag tattccttgt attgttaaag aaaatctaac ggataaagaa gcctatacct
     4501 atgtaattga aacaaacctt atacagcgtt ctttctccga tttactgccg acggaaaaag
     4561 cccttgttct taaaatgaga tatgaaaaaa tagcaagtca gggcaagaga aatgatttgc
     4621 aaaaggagat aaacaattta gatcagggaa ttatagaaaa ggaaagtaaa gaggaagata
     4681 aaatagacag cagaaaaaca cttggaaaag aatataatct ttcaggggca tctattgcaa
     4741 ggtacctaag attaaatgaa ttatctaagt cttggaaaaa agatgtggat gaagataaaa
     4801 taggtttgac gatggcagta gatttatcct atctttccaa agaaatacag gaatatctgt
     4861 atcagaagtg cgaagaattg gaactaagtt taaaaccaag cgatgccaaa gcactccatc
     4921 tgatgaacag acaagaagat ctgaatcaag agatggttat aacatacttg ctgaacttga
     4981 aaaaaacgaa ggtaaaaaag tatcagaata tcaaactatc tcagagtgtc tataaaaagt
     5041 tttttcatga tgaaaggaaa gaagatgtag aagaaattat agaaaaagca ttggaaattt
     5101 actttaagga atatattggt cagtgaaaag acaaaattat aaatttaagg tataatataa
     5161 ggtattaaaa agggaaaaga cctgtttaac aggataagat ataaaagagg caggtgtcag
     5221 aatggacgaa ataaaattgt atgaaaataa agagatacgc tccatttggg acgaagaaaa
     5281 agaagagtgg tatttttcag tagtcgatgt agttggagtt ttgacagaac aagaaaacgt
     5341 aagaggtgct agtacctatt gggctgtact aaaaaagaga ttaaaagaag aaggaaatga
     5401 actgcttaca atttgtaagc agttgaaaat gaaagcaaca gatggaaaaa tgcgtttaac
     5461 tgatgtagca gatatgcaag gaatattccg tattatccag tccatcccat cccctaaagc
     5521 agaacctttt aagttatggc ttgctgaggt tggaaaagaa cgaattgatg aaattatcga
     5581 tcctgaactt acgattgaca gagccttaga aacttatcta aagaagggat atacacgtga
     5641 gtggataaat caaagacttc aagccattca ggtaagaaaa gaactgactg atgcttggga
     5701 tgaccatggg atacaaaaag gcaaagaata cgcaattctt actgatgaaa tcaccaaagc
     5761 atggtccgga atgacaacaa gaggttataa aaatctgaag ggtttgaaaa aggaaaatct
     5821 aagggataat atgaccactc ttgaaatagt tcttaatatg cttgcagaag ccacaacaac
     5881 aaacgcatta aagcaaagct aaaaggactt ag
//
